Guide to the Human Genome
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Search of human proteins with 150170658

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|150170658 hypothetical protein LOC137392 [Homo sapiens]
         (289 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|150170658 hypothetical protein LOC137392 [Homo sapiens]            563   e-161
gi|38348294 hypothetical protein LOC339145 [Homo sapiens]             241   7e-64
gi|23111038 sorting nexin 2 [Homo sapiens]                             44   2e-04
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    44   2e-04
gi|8923904 bridging integrator 3 [Homo sapiens]                        39   0.004
gi|64085252 hypothetical protein LOC145508 [Homo sapiens]              39   0.007
gi|196115290 glial fibrillary acidic protein isoform 2 [Homo sap...    37   0.020
gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]    37   0.020
gi|58530840 desmoplakin isoform I [Homo sapiens]                       37   0.020
gi|156104874 envoplakin [Homo sapiens]                                 35   0.059
gi|22748643 chromatin modifying protein 4C [Homo sapiens]              35   0.077
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    35   0.077
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      35   0.10 
gi|42794779 myosin 18A isoform b [Homo sapiens]                        35   0.10 
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s...    34   0.17 
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s...    34   0.17 
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s...    34   0.17 
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s...    34   0.17 
gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]      34   0.17 
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora...    33   0.22 
gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]               33   0.22 
gi|170650670 Leber congenital amaurosis 5 [Homo sapiens]               33   0.22 
gi|40807469 TRAF interacting protein [Homo sapiens]                    33   0.29 
gi|33946313 ninein isoform 4 [Homo sapiens]                            33   0.29 
gi|33946321 ninein isoform 5 [Homo sapiens]                            33   0.29 
gi|148536871 ninein isoform 1 [Homo sapiens]                           33   0.29 
gi|148536869 ninein isoform 2 [Homo sapiens]                           33   0.29 
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          33   0.29 
gi|56961680 coiled-coil domain containing 147 [Homo sapiens]           33   0.29 
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    33   0.38 

>gi|150170658 hypothetical protein LOC137392 [Homo sapiens]
          Length = 289

 Score =  563 bits (1452), Expect = e-161
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 1   MMRRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAA 60
           MMRRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAA
Sbjct: 1   MMRRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAA 60

Query: 61  TETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTAR 120
           TETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTAR
Sbjct: 61  TETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTAR 120

Query: 121 NREAKQLTQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKMKDI 180
           NREAKQLTQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKMKDI
Sbjct: 121 NREAKQLTQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKMKDI 180

Query: 181 KTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDEDEDLEVFRNSLYAPDYSSRLDIVRAN 240
           KTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDEDEDLEVFRNSLYAPDYSSRLDIVRAN
Sbjct: 181 KTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDEDEDLEVFRNSLYAPDYSSRLDIVRAN 240

Query: 241 SKSPLQRSLSAKCVSGTGQVSTCRLRKDQQAEDDEDDELDVTEEENFLK 289
           SKSPLQRSLSAKCVSGTGQVSTCRLRKDQQAEDDEDDELDVTEEENFLK
Sbjct: 241 SKSPLQRSLSAKCVSGTGQVSTCRLRKDQQAEDDEDDELDVTEEENFLK 289


>gi|38348294 hypothetical protein LOC339145 [Homo sapiens]
          Length = 304

 Score =  241 bits (614), Expect = 7e-64
 Identities = 125/265 (47%), Positives = 181/265 (68%), Gaps = 6/265 (2%)

Query: 8   NRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAATETPHLK 67
           +R++Q + ++  V+N EK+FG+ C + AAY RKTARLRDKAD LV ++  +A +E P L+
Sbjct: 6   SRDSQVRVMENTVANTEKYFGQFCSLLAAYTRKTARLRDKADQLVKQLIDFANSENPELR 65

Query: 68  LGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTARNREAKQL 127
             +  FA++ AK+QDYRQA+VERLE KVV PLK YG  +K  R ++K     +N E KQL
Sbjct: 66  ATMRGFAEDLAKVQDYRQAQVERLETKVVNPLKLYGAQIKQTRAEIKKFKHVQNHEIKQL 125

Query: 128 TQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKMKDIKTIFSEF 187
            +LE+ RQ++PSD+ +ISQAET +QRAA+D+SRT+  LEET++ F+RQK+KD++  F +F
Sbjct: 126 EKLEKLRQKSPSDQQMISQAETRVQRAAVDSSRTTLQLEETVDGFQRQKLKDLQKFFCDF 185

Query: 188 ITIEMLFHGKALEVYTAAYQNIQNIDEDEDLEVFRNSLYA--PDYSSRLDIVRANSKSPL 245
           +TIEM+FH KA+EVY++A+Q ++  D + DL  FR  +      Y +RL    AN+ SP 
Sbjct: 186 VTIEMVFHAKAVEVYSSAFQTLEKYDLERDLLDFRAKMQGVYGHYDTRL---LANT-SPP 241

Query: 246 QRSLSAKCVSGTGQVSTCRLRKDQQ 270
              L +    GT QV   R  +D +
Sbjct: 242 PSVLQSLASQGTLQVQLSRANEDPE 266


>gi|23111038 sorting nexin 2 [Homo sapiens]
          Length = 519

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 41/190 (21%), Positives = 88/190 (46%), Gaps = 9/190 (4%)

Query: 3   RRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKAD--LLVNEINAYAA 60
           ++  EN + Q ++L  +V  +  H  EL    AA+ +  A L +  D   L   ++  A 
Sbjct: 310 QQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAE 369

Query: 61  TETPHLKLGLMNFADEFAKLQDYRQ--AEVERLEAKVVEPLKTYGTIVKMKRDDLKATLT 118
            E    K+  ++    FA    + +  ++  RL A  V+ +  +      K +D + TL 
Sbjct: 370 VEE---KIDQLHQEQAFADFYMFSELLSDYIRLIA-AVKGVFDHRMKCWQKWEDAQITLL 425

Query: 119 ARNREAKQLTQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKMK 178
            + REA+    +     +    ++ I + E ++Q+   D  + S+ + + +  FE++++K
Sbjct: 426 -KKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVK 484

Query: 179 DIKTIFSEFI 188
           D KT+  +++
Sbjct: 485 DFKTVIIKYL 494


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 42/190 (22%), Positives = 87/190 (45%), Gaps = 17/190 (8%)

Query: 2    MRRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRK---TARLRDKADLLVNEINAY 58
            +R+T E  N   ++L+T+ SNVE++   +  +  +  ++   T  +R   ++ + E    
Sbjct: 941  LRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKE---- 996

Query: 59   AATETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLT 118
            +A     L+  LM    E  +LQD ++  +E +E ++ E  KT  ++    ++ L+   T
Sbjct: 997  SAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRAST 1056

Query: 119  A------RNREAKQLTQLERTRQRNPSDRHVISQAETELQRAAMD----ASRTSRHLEET 168
            A        R+ ++  ++    Q       ++  A+ E  +AA +     +   +HLEET
Sbjct: 1057 ALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEET 1116

Query: 169  INNFERQKMK 178
                E Q ++
Sbjct: 1117 TQKAESQLLE 1126



 Score = 35.0 bits (79), Expect = 0.077
 Identities = 61/327 (18%), Positives = 125/327 (38%), Gaps = 53/327 (16%)

Query: 1    MMRRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAA 60
            M+R   E      +Q+Q  V  +E     L +  A    K+  L+ +  LL  ++  + A
Sbjct: 1278 MLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKA 1337

Query: 61   TETPHLKLGLMNFADEFAKLQDYRQA----------EVERLEAKV-------------VE 97
                 +        +E+ KL   ++           E+ RL+A++             ++
Sbjct: 1338 RNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQ 1397

Query: 98   PLKTYGTIVKMKRDDLKATLTAR----NREAKQLTQLERTRQRNPSDRHVISQAETELQR 153
             LK     V+ +++ ++  L A+      + K +TQ+++  +R  +    +   + ++  
Sbjct: 1398 SLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVME 1457

Query: 154  AAMDASRTSRHLEETINNFERQKMKDI--------KTIFSEFITIEMLFHGKALEVYTAA 205
             +  A  +  H E+ ++  E Q++K+         K++ S+   ++     K  E     
Sbjct: 1458 TS--AQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQ 1515

Query: 206  YQNIQNIDE----DEDL-------EVFRNSLYAPDYSSRLDIVRANSKSPLQRSLSAKCV 254
             Q +Q   E     +DL       E  R  +   +  +R  IV A SK      +  +  
Sbjct: 1516 EQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLT 1575

Query: 255  SGTGQVSTCRLRKDQQAEDDEDDELDV 281
                +     L++   A D + DELDV
Sbjct: 1576 KENEE-----LKQRNGALDQQKDELDV 1597


>gi|8923904 bridging integrator 3 [Homo sapiens]
          Length = 253

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 37/204 (18%), Positives = 84/204 (41%), Gaps = 10/204 (4%)

Query: 2   MRRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAAT 61
           + R  E    + +QL+     ++K   +      A  +   ++    DLL N +      
Sbjct: 20  VERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKI--SLDLLSNPL-----C 72

Query: 62  ETPHLKLGLMNFADEFAKLQD-YRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTAR 120
           E     L ++   D   K  D + Q +V +++  V+EPLK +G++       +K    A 
Sbjct: 73  EQDQDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQAL 132

Query: 121 NREAKQLTQLERTRQRNPSDRHV--ISQAETELQRAAMDASRTSRHLEETINNFERQKMK 178
               +   ++E+  ++  +   +  + QA  EL+    D    +R L E +  F   ++ 
Sbjct: 133 QDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLD 192

Query: 179 DIKTIFSEFITIEMLFHGKALEVY 202
             +  F   I  +++++ +  +++
Sbjct: 193 YFQPSFESLIRAQVVYYSEMHKIF 216


>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
          Length = 1094

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 41/185 (22%), Positives = 79/185 (42%), Gaps = 21/185 (11%)

Query: 2   MRRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAAT 61
           + R LEN   Q  Q+   +  ++ HF + C+            R  ADL ++E+  +A  
Sbjct: 405 LTRELENGEKQQLQMLDRLKEIQNHF-DTCE----------AERKHADLQISELTRHAED 453

Query: 62  ETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTARN 121
            T   +  L       A L++  +   E L+ K  E ++ +    K+K   L+  L  ++
Sbjct: 454 ATKQAERYLSELQQSEA-LKEEAEKRREDLKLKAQESIRQW----KLKHKKLERALEKQS 508

Query: 122 REAKQLT----QLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKM 177
               +LT    Q+ + +    +  +   Q    L++   D   T R L+E   + + +K+
Sbjct: 509 ETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKELNDV-LTKRALQEEELHSKEEKL 567

Query: 178 KDIKT 182
           +DIK+
Sbjct: 568 RDIKS 572


>gi|196115290 glial fibrillary acidic protein isoform 2 [Homo
           sapiens]
          Length = 431

 Score = 37.0 bits (84), Expect = 0.020
 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 18/155 (11%)

Query: 29  ELCQIFAAYVRKTARLRDKADLLVNEINAYAATETPHLKLGLMNFADEFAKLQDYRQAEV 88
           EL   FA+Y+ K   L  +   L  E+N   A E                KL D  QAE+
Sbjct: 75  ELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEP--------------TKLADVYQAEL 120

Query: 89  ERLEAKVVEPLKTYGTIVKMKRDDLKATLTARNREAKQLTQLERTRQRNPSDRHVISQAE 148
             L  + ++ L      ++++RD+L   L    ++ +  T L    + N +      Q  
Sbjct: 121 RELRLR-LDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLA---AYRQEA 176

Query: 149 TELQRAAMDASRTSRHLEETINNFERQKMKDIKTI 183
            E   A +D  R    LEE I    +   ++++ +
Sbjct: 177 DEATLARLDLERKIESLEEEIRFLRKIHEEEVREL 211


>gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]
          Length = 432

 Score = 37.0 bits (84), Expect = 0.020
 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 18/155 (11%)

Query: 29  ELCQIFAAYVRKTARLRDKADLLVNEINAYAATETPHLKLGLMNFADEFAKLQDYRQAEV 88
           EL   FA+Y+ K   L  +   L  E+N   A E                KL D  QAE+
Sbjct: 75  ELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEP--------------TKLADVYQAEL 120

Query: 89  ERLEAKVVEPLKTYGTIVKMKRDDLKATLTARNREAKQLTQLERTRQRNPSDRHVISQAE 148
             L  + ++ L      ++++RD+L   L    ++ +  T L    + N +      Q  
Sbjct: 121 RELRLR-LDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLA---AYRQEA 176

Query: 149 TELQRAAMDASRTSRHLEETINNFERQKMKDIKTI 183
            E   A +D  R    LEE I    +   ++++ +
Sbjct: 177 DEATLARLDLERKIESLEEEIRFLRKIHEEEVREL 211


>gi|58530840 desmoplakin isoform I [Homo sapiens]
          Length = 2871

 Score = 37.0 bits (84), Expect = 0.020
 Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 5/96 (5%)

Query: 84   RQAEVERLEAKVVEPLKTYGTI-VKMKRDDLKATLTARNREAKQLTQLERTRQRNPSDRH 142
            R+ ++E +E + V  ++T  ++  K   DD   T+  +N+E ++L QL     +  +DR 
Sbjct: 1443 RKQQLE-VELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLI---DKETNDRK 1498

Query: 143  VISQAETELQRAAMDASRTSRHLEETINNFERQKMK 178
             +      LQR   D  + +    ETIN  + Q+ +
Sbjct: 1499 CLEDENARLQRVQYDLQKANSSATETINKLKVQEQE 1534


>gi|156104874 envoplakin [Homo sapiens]
          Length = 2033

 Score = 35.4 bits (80), Expect = 0.059
 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 12/106 (11%)

Query: 85   QAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTAR-----NRE--AKQLTQLERTRQRN 137
            Q +++ L+    +    Y  ++++++D +     AR     NRE  A+Q  + E  R R 
Sbjct: 1503 QVQIDVLQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAREEEARRLRE 1562

Query: 138  PSDR-----HVISQAETELQRAAMDASRTSRHLEETINNFERQKMK 178
              DR        S+ E+ELQRA   A +    L++ +   ERQK +
Sbjct: 1563 RIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQ 1608


>gi|22748643 chromatin modifying protein 4C [Homo sapiens]
          Length = 233

 Score = 35.0 bits (79), Expect = 0.077
 Identities = 58/227 (25%), Positives = 95/227 (41%), Gaps = 28/227 (12%)

Query: 59  AATETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLT 118
           AA       + L    +   K Q+Y +  ++R  A      K +GT  + KR  L+A L 
Sbjct: 18  AAPSPQEALVRLRETEEMLGKKQEYLENRIQREIALA----KKHGT--QNKRAALQA-LK 70

Query: 119 ARNREAKQLTQLERTRQRNPSDRHVI--SQAETELQRAAMDASRTSRHLEETINNFERQK 176
            + R  KQLTQ++ T       R  +  S   TE+ R    A++  + + E   N +  K
Sbjct: 71  RKKRFEKQLTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKSVHE---NMDLNK 127

Query: 177 MKDIKTIFSEFITIEMLFHGKALEVYTAAYQNI---QNIDEDEDLEVFRNSLYAPDYSSR 233
           + D+    +E   I       A E+  A  Q +    + DEDE L      L   + + +
Sbjct: 128 IDDLMQEITEQQDI-------AQEISEAFSQRVGFGDDFDEDE-LMAELEELEQEELNKK 179

Query: 234 LDIVRANSKSPLQRSLSAKCVSGTGQVSTCRLRK---DQQAEDDEDD 277
           +  +R  +      SL A+     G  ST R  +    Q+AE+++DD
Sbjct: 180 MTNIRLPNVP--SSSLPAQPNRKPGMSSTARRSRAASSQRAEEEDDD 224


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 35.0 bits (79), Expect = 0.077
 Identities = 38/195 (19%), Positives = 84/195 (43%), Gaps = 18/195 (9%)

Query: 7    ENRNA--QTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAATETP 64
            EN+ A  +T QL   +  ++K   +      ++V+  + L++  D +V +   Y   E  
Sbjct: 2430 ENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGD---YQQLEER 2486

Query: 65   HLKLGL------MNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLT 118
            HL + L         A E  KL++  +     ++    E  K    +++  R+DL   +T
Sbjct: 2487 HLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQY-REDLNQVIT 2545

Query: 119  ARNREAKQLTQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKMK 178
             ++ + KQL +++  + +   +++       +L+    ++   +  L  + N  + +K  
Sbjct: 2546 IKDSQQKQLLEVQLQQNKELENKY------AKLEEKLKESEEANEDLRRSFNALQEEKQD 2599

Query: 179  DIKTIFSEFITIEML 193
              K I S  ++I  L
Sbjct: 2600 LSKEIESLKVSISQL 2614



 Score = 33.1 bits (74), Expect = 0.29
 Identities = 37/161 (22%), Positives = 71/161 (44%), Gaps = 21/161 (13%)

Query: 59  AATETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLT 118
           A  E   LKL L     E A  +   Q E++++E + + P+K     +K+  +D      
Sbjct: 569 AQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIK-----MKVFLEDTGQDFP 623

Query: 119 ARNREAKQLTQLERTR-----QRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFE 173
               E   L  +E+ +     Q   S+   ++ A  EL+    D  ++   + + I    
Sbjct: 624 LMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPD-IGQCH 682

Query: 174 RQKMKDIKTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDE 214
           + +++ +K   S+ + +E+ FH KA E+Y       +N+DE
Sbjct: 683 QDELERLK---SQILELELNFH-KAQEIYE------KNLDE 713



 Score = 31.6 bits (70), Expect = 0.85
 Identities = 46/192 (23%), Positives = 86/192 (44%), Gaps = 28/192 (14%)

Query: 10   NAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYA-----ATETP 64
            N + K++Q    N++    +L    AA+ +  + L+D  D +++E   +      A ++ 
Sbjct: 2167 NKKDKEVQQLQENLDSTVTQL----AAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSK 2222

Query: 65   HLKLGLMNFADEFAKLQDY-RQAEVERLEAKV-VEPLKTYGTIVKMK-------RDDLKA 115
              ++ L    D  + L+D  RQ  +   E K+ +  L+    I + K       +  +  
Sbjct: 2223 EEEIRLKE--DNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2280

Query: 116  TLTARNREAKQLTQLERTRQRNPSDRHVISQAETELQR---AAMDASRTSRHLEETINNF 172
            TL   N+E   L+QLE TR    S ++ +++ E+EL+       D S +    +E   N 
Sbjct: 2281 TLQGENKEL--LSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNL 2338

Query: 173  E---RQKMKDIK 181
            E   RQ+  DI+
Sbjct: 2339 EGIIRQQEADIQ 2350


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 14/140 (10%)

Query: 155 AMDASRTSRHLEETINNFERQKMKDIKTIFSEFITIEMLFHGKALEVYTAAYQNI----- 209
           A +  +++ HL E   + E ++   I++ +S  +   MLF         A  Q +     
Sbjct: 135 ARNIVQSTEHLHEDNGDVEVRRSCRIRSRYSG-VNQSMLFDKLITNTAEAVLQKMDDMKK 193

Query: 210 ---QNIDEDEDLEVFRNSLYAPDYSSRLDIVRANSKSPLQRSLSAKCVSGTGQVSTCRLR 266
              Q + E EDL VF  +       S L++     +  +QR+      +  G V +    
Sbjct: 194 MRRQRMRELEDLGVFNET-----EESNLNMYTRGKQKDIQRTDEETTDNQEGSVESSEEG 248

Query: 267 KDQQAEDDEDDELDVTEEEN 286
           +DQ+ EDD +DE D  ++++
Sbjct: 249 EDQEHEDDGEDEDDEDDDDD 268


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 55/217 (25%), Positives = 87/217 (40%), Gaps = 39/217 (17%)

Query: 82   DYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTARNREAKQLTQLERTRQRNPSDR 141
            ++ + +V+RLE+ +   LK     +  +RD     + A NRE +Q  +L+R  +    + 
Sbjct: 1832 EFERTQVKRLES-LASRLKENMEKLTEERDQ---RIAAENREKEQNKRLQRQLRDTKEEM 1887

Query: 142  HVISQAETELQRAAMDASRTSRHLEETINNFE---RQKMKDIKTIFSEFITIEMLFHGKA 198
                    EL R   +ASR    LE  + + E   +    D+K  F            K 
Sbjct: 1888 -------GELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAF------------KR 1928

Query: 199  LEVYTAAYQNIQNIDEDEDLEVFRNSLYAPDYSSRLDIVRANSKSPLQRSLS-AKCVSGT 257
            +    AA ++    DE+EDL    NS    D  S L+      KS L ++   +K  S  
Sbjct: 1929 IGDLQAAIEDEMESDENEDL---INSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDD 1985

Query: 258  GQVSTC-------RLRKDQQAEDDEDDELDVTEEENF 287
            G + +         L  D+   DDE D LD T    +
Sbjct: 1986 GSLKSSSPTSYWKSLAPDR--SDDEHDPLDNTSRPRY 2020


>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
           sapiens]
          Length = 457

 Score = 33.9 bits (76), Expect = 0.17
 Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 16/158 (10%)

Query: 71  MNFADEFAKLQDYRQAEVERLEAKVVEPLKT---YGTIVKMKRDDLKATLTARNREAKQL 127
           +N  +   K Q+ R+ E++     V E ++     G     K ++   +  +  RE  +L
Sbjct: 285 VNIFEYGLKQQEKRKTELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELEL 344

Query: 128 TQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKM-------KDI 180
             +E+      +D   +  A   L+   ++       LEETIN FER  +       +++
Sbjct: 345 PNIEKMILECSADISELFDALMTLEMQLVE------QLEETINMFERNIVDMVGLFIENV 398

Query: 181 KTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDEDEDL 218
           +++ ++   +E   H K LE+  +  + I   D DEDL
Sbjct: 399 QSLMAQCRDLENHHHEKLLEISISTLEKIVEGDLDEDL 436


>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
           sapiens]
          Length = 457

 Score = 33.9 bits (76), Expect = 0.17
 Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 16/158 (10%)

Query: 71  MNFADEFAKLQDYRQAEVERLEAKVVEPLKT---YGTIVKMKRDDLKATLTARNREAKQL 127
           +N  +   K Q+ R+ E++     V E ++     G     K ++   +  +  RE  +L
Sbjct: 285 VNIFEYGLKQQEKRKTELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELEL 344

Query: 128 TQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKM-------KDI 180
             +E+      +D   +  A   L+   ++       LEETIN FER  +       +++
Sbjct: 345 PNIEKMILECSADISELFDALMTLEMQLVE------QLEETINMFERNIVDMVGLFIENV 398

Query: 181 KTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDEDEDL 218
           +++ ++   +E   H K LE+  +  + I   D DEDL
Sbjct: 399 QSLMAQCRDLENHHHEKLLEISISTLEKIVEGDLDEDL 436


>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
           sapiens]
          Length = 523

 Score = 33.9 bits (76), Expect = 0.17
 Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 16/158 (10%)

Query: 71  MNFADEFAKLQDYRQAEVERLEAKVVEPLKT---YGTIVKMKRDDLKATLTARNREAKQL 127
           +N  +   K Q+ R+ E++     V E ++     G     K ++   +  +  RE  +L
Sbjct: 285 VNIFEYGLKQQEKRKTELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELEL 344

Query: 128 TQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKM-------KDI 180
             +E+      +D   +  A   L+   ++       LEETIN FER  +       +++
Sbjct: 345 PNIEKMILECSADISELFDALMTLEMQLVE------QLEETINMFERNIVDMVGLFIENV 398

Query: 181 KTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDEDEDL 218
           +++ ++   +E   H K LE+  +  + I   D DEDL
Sbjct: 399 QSLMAQCRDLENHHHEKLLEISISTLEKIVEGDLDEDL 436


>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
           sapiens]
          Length = 523

 Score = 33.9 bits (76), Expect = 0.17
 Identities = 36/158 (22%), Positives = 69/158 (43%), Gaps = 16/158 (10%)

Query: 71  MNFADEFAKLQDYRQAEVERLEAKVVEPLKT---YGTIVKMKRDDLKATLTARNREAKQL 127
           +N  +   K Q+ R+ E++     V E ++     G     K ++   +  +  RE  +L
Sbjct: 285 VNIFEYGLKQQEKRKTELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELEL 344

Query: 128 TQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKM-------KDI 180
             +E+      +D   +  A   L+   ++       LEETIN FER  +       +++
Sbjct: 345 PNIEKMILECSADISELFDALMTLEMQLVE------QLEETINMFERNIVDMVGLFIENV 398

Query: 181 KTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDEDEDL 218
           +++ ++   +E   H K LE+  +  + I   D DEDL
Sbjct: 399 QSLMAQCRDLENHHHEKLLEISISTLEKIVEGDLDEDL 436


>gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]
          Length = 757

 Score = 33.9 bits (76), Expect = 0.17
 Identities = 28/125 (22%), Positives = 57/125 (45%), Gaps = 12/125 (9%)

Query: 43  RLRDKADLLVNEINAYAATETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTY 102
           +LR+KA  +   +  +  TE  ++KL    F ++   + +Y       L    V PL+  
Sbjct: 144 QLREKAGDVRRNLRDFELTEEQYIKLKA--FPEDQLSIPEYVSVRFYEL----VNPLRKE 197

Query: 103 GTIVKMKRDDLKATLTARNREAKQLTQLERTRQRNPSDRHVISQAETELQRAAMDASRTS 162
              +++K++ L   L+    + KQLT+          DR   S+ +   QR A++ + T 
Sbjct: 198 ICELQVKKNILAEELSTNKNQLKQLTETYE------EDRKNYSEVQIRCQRLALELADTK 251

Query: 163 RHLEE 167
           + +++
Sbjct: 252 QLIQQ 256


>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 2 [Homo
            sapiens]
          Length = 1651

 Score = 33.5 bits (75), Expect = 0.22
 Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 7/66 (10%)

Query: 104  TIVKMKRDDLKATLTARNREAKQLTQLERTRQRNPSDRHVISQAETELQRAAMDASRTSR 163
            T++ M+R  L+A   AR+ E ++  QLE  R+R   DR     A  E +R   +  RT R
Sbjct: 1590 TMLIMQR--LEAERRARDEERRRQQQLEEMRKREAEDR-----ARQEEERRRQEEERTKR 1642

Query: 164  HLEETI 169
              EE +
Sbjct: 1643 DAEEKV 1648


>gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]
          Length = 697

 Score = 33.5 bits (75), Expect = 0.22
 Identities = 57/285 (20%), Positives = 108/285 (37%), Gaps = 40/285 (14%)

Query: 3   RRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVR---KTARLRDKADLLVNEINAYA 59
           +R L  R  +  +LQ  VS ++    EL +   +  R   +  +  +K +   NEI+   
Sbjct: 102 KRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLI 161

Query: 60  ATETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTA 119
                 +        +   K Q+  +A  +R++    E  +T  ++ K+K       L  
Sbjct: 162 FRHNNEITA----LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPE 217

Query: 120 RNREAKQLTQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKMKD 179
           R+  AK+L                   AE +L          S++LE + N+F+RQ + +
Sbjct: 218 RDDLAKKLVS-----------------AELKLDDTERRIKELSKNLELSTNSFQRQLLAE 260

Query: 180 IKTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDEDEDLEVFRNSLYAPDYSSRLDIVRA 239
            K  +      ++L      +     Y  ++  + + D++          YS+RL     
Sbjct: 261 RKRAYEAHDENKVL-----QKEVQRLYHKLKEKERELDIKNI--------YSNRLPKSSP 307

Query: 240 NSKSPLQRSLSAKCVSGTGQVSTCRLRKDQQAEDDEDDELDVTEE 284
           N +  L    +A C S    + T   +  Q  ED + +E  +T E
Sbjct: 308 NKEKELALRKNAACQSDFADLCT---KGVQTMEDFKPEEYPLTPE 349


>gi|170650670 Leber congenital amaurosis 5 [Homo sapiens]
          Length = 697

 Score = 33.5 bits (75), Expect = 0.22
 Identities = 57/285 (20%), Positives = 108/285 (37%), Gaps = 40/285 (14%)

Query: 3   RRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVR---KTARLRDKADLLVNEINAYA 59
           +R L  R  +  +LQ  VS ++    EL +   +  R   +  +  +K +   NEI+   
Sbjct: 102 KRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLI 161

Query: 60  ATETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTA 119
                 +        +   K Q+  +A  +R++    E  +T  ++ K+K       L  
Sbjct: 162 FRHNNEITA----LKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPE 217

Query: 120 RNREAKQLTQLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFERQKMKD 179
           R+  AK+L                   AE +L          S++LE + N+F+RQ + +
Sbjct: 218 RDDLAKKLVS-----------------AELKLDDTERRIKELSKNLELSTNSFQRQLLAE 260

Query: 180 IKTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDEDEDLEVFRNSLYAPDYSSRLDIVRA 239
            K  +      ++L      +     Y  ++  + + D++          YS+RL     
Sbjct: 261 RKRAYEAHDENKVL-----QKEVQRLYHKLKEKERELDIKNI--------YSNRLPKSSP 307

Query: 240 NSKSPLQRSLSAKCVSGTGQVSTCRLRKDQQAEDDEDDELDVTEE 284
           N +  L    +A C S    + T   +  Q  ED + +E  +T E
Sbjct: 308 NKEKELALRKNAACQSDFADLCT---KGVQTMEDFKPEEYPLTPE 349


>gi|40807469 TRAF interacting protein [Homo sapiens]
          Length = 469

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 43/186 (23%), Positives = 70/186 (37%), Gaps = 30/186 (16%)

Query: 2   MRRTLENRNAQTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAAT 61
           +R TLE RNA    LQ A+   E     LC      ++   + +D+            A 
Sbjct: 107 LRDTLEERNATVVSLQQALGKAEM----LCSTLKKQMKYLEQQQDETK---------QAQ 153

Query: 62  ETPHLKLGLMNFADEFAKLQDYRQAEVERL------EAKVVEPLKTYGTIVKMKRDDLKA 115
           E        M   ++   L   ++ EVE +          VE L  Y   +K + ++LK 
Sbjct: 154 EEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKE 213

Query: 116 TLTARNREAKQLTQ-LERTRQRNPSDRHVISQAETELQRAAMDASRTSRH---------- 164
              A    A +L + L  +R +  +    + QA+ EL+ A  D     +           
Sbjct: 214 ARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSADKEIMSLKKKLTM 273

Query: 165 LEETIN 170
           L+ET+N
Sbjct: 274 LQETLN 279


>gi|33946313 ninein isoform 4 [Homo sapiens]
          Length = 2096

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 39/173 (22%), Positives = 71/173 (41%), Gaps = 23/173 (13%)

Query: 12   QTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAATETPHLKLGLM 71
            + ++LQT V N +    EL        +  + L  K    +N       TE    KL L 
Sbjct: 1861 ENERLQTMVQNTK---AELTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQE--KLSLK 1915

Query: 72   NFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTARNREAKQLTQLE 131
               D+F K Q     +V ++ + + + L+T    + ++ + LK      + +  ++  L 
Sbjct: 1916 RECDQFQKEQSPANRKVSQMNS-LEQELET----IHLENEGLKKKQVKLDEQLMEMQHLR 1970

Query: 132  RTRQRNPS----DRHVISQAET---------ELQRAAMDASRTSRHLEETINN 171
             T   +PS    D  ++ Q            +LQR  + A R ++HL+E + N
Sbjct: 1971 STATPSPSPHAWDLQLLQQQACPMVPREQFLQLQRQLLQAERINQHLQEELEN 2023


>gi|33946321 ninein isoform 5 [Homo sapiens]
          Length = 2090

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 39/173 (22%), Positives = 71/173 (41%), Gaps = 23/173 (13%)

Query: 12   QTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAATETPHLKLGLM 71
            + ++LQT V N +    EL        +  + L  K    +N       TE    KL L 
Sbjct: 1855 ENERLQTMVQNTK---AELTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQE--KLSLK 1909

Query: 72   NFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTARNREAKQLTQLE 131
               D+F K Q     +V ++ + + + L+T    + ++ + LK      + +  ++  L 
Sbjct: 1910 RECDQFQKEQSPANRKVSQMNS-LEQELET----IHLENEGLKKKQVKLDEQLMEMQHLR 1964

Query: 132  RTRQRNPS----DRHVISQAET---------ELQRAAMDASRTSRHLEETINN 171
             T   +PS    D  ++ Q            +LQR  + A R ++HL+E + N
Sbjct: 1965 STATPSPSPHAWDLQLLQQQACPMVPREQFLQLQRQLLQAERINQHLQEELEN 2017


>gi|148536871 ninein isoform 1 [Homo sapiens]
          Length = 2046

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 39/173 (22%), Positives = 71/173 (41%), Gaps = 23/173 (13%)

Query: 12   QTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAATETPHLKLGLM 71
            + ++LQT V N +    EL        +  + L  K    +N       TE    KL L 
Sbjct: 1855 ENERLQTMVQNTK---AELTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQE--KLSLK 1909

Query: 72   NFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTARNREAKQLTQLE 131
               D+F K Q     +V ++ + + + L+T    + ++ + LK      + +  ++  L 
Sbjct: 1910 RECDQFQKEQSPANRKVSQMNS-LEQELET----IHLENEGLKKKQVKLDEQLMEMQHLR 1964

Query: 132  RTRQRNPS----DRHVISQAET---------ELQRAAMDASRTSRHLEETINN 171
             T   +PS    D  ++ Q            +LQR  + A R ++HL+E + N
Sbjct: 1965 STATPSPSPHAWDLQLLQQQACPMVPREQFLQLQRQLLQAERINQHLQEELEN 2017


>gi|148536869 ninein isoform 2 [Homo sapiens]
          Length = 2133

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 39/173 (22%), Positives = 71/173 (41%), Gaps = 23/173 (13%)

Query: 12   QTKQLQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAATETPHLKLGLM 71
            + ++LQT V N +    EL        +  + L  K    +N       TE    KL L 
Sbjct: 1855 ENERLQTMVQNTK---AELTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQE--KLSLK 1909

Query: 72   NFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTARNREAKQLTQLE 131
               D+F K Q     +V ++ + + + L+T    + ++ + LK      + +  ++  L 
Sbjct: 1910 RECDQFQKEQSPANRKVSQMNS-LEQELET----IHLENEGLKKKQVKLDEQLMEMQHLR 1964

Query: 132  RTRQRNPS----DRHVISQAET---------ELQRAAMDASRTSRHLEETINN 171
             T   +PS    D  ++ Q            +LQR  + A R ++HL+E + N
Sbjct: 1965 STATPSPSPHAWDLQLLQQQACPMVPREQFLQLQRQLLQAERINQHLQEELEN 2017


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 44/253 (17%), Positives = 110/253 (43%), Gaps = 27/253 (10%)

Query: 43  RLRDKADLLVNEI----NAYAATETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEP 98
           RL+ +     NE+     +++ T+   LK  L     ++   QD  Q E+ +++ ++   
Sbjct: 340 RLQRELKCAQNEVLRFQTSHSVTQNEELKSRLCTLQKKYDTSQD-EQNELLKMQLQLQTE 398

Query: 99  LKTYGTIVKMKRDDLKATLTARNREAKQLTQLERTRQRNPS---DRHVISQAETELQRAA 155
           L+            +K+TL     E + L +L++   ++ +   ++  + + + +LQ   
Sbjct: 399 LRQLKV--------MKSTLVENQSEKELLCRLQKLHLQHQNVTCEKEKLLERQQQLQEEL 450

Query: 156 MDASRTSRHLEETINNFERQKMKDIKTIFSEFITIEMLFHGKALEVYTAAYQNIQNIDED 215
                  +HL +T+ +F+    KD +T  ++   ++ L+     E+    +   Q +++D
Sbjct: 451 QCHEAELQHLRDTVASFKESNEKDTET-HAQLQEMKQLYQASKDELERQKHMYDQ-LEQD 508

Query: 216 -----EDLEVFRNSLYAPD----YSSRLDIVRANSKSPLQRSLSAKCVSGTGQVSTCRLR 266
                 +L+  + S   P+     +++ D + +      ++  +++   G  Q+  C L 
Sbjct: 509 LLLCQLELKELKASHPIPEDKGKCANKCDTLLSRLTELQEKYKASQKEMGQLQMEQCELL 568

Query: 267 KDQQAEDDEDDEL 279
           +DQ+   +E  +L
Sbjct: 569 EDQRRMQEEQGQL 581


>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
          Length = 872

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 41/199 (20%), Positives = 81/199 (40%), Gaps = 16/199 (8%)

Query: 106 VKMKRDDLKATLTARNREAKQLTQLERTRQRNPSD-RHVISQAETELQRAAMDASRTSRH 164
           V  +RD L + +        Q T+ ++  +R+  +  H ISQ + E+Q+   +ASR  R 
Sbjct: 158 VTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRK 217

Query: 165 LEETINNFERQKMKDIKTIFSEFITIEMLFHGKALEVYTAAY----QNIQNIDEDEDLEV 220
            +E +    +Q   D+ +  +E   ++        E+         Q I N    ++LE 
Sbjct: 218 -KEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQ 276

Query: 221 F--RNSLYAPDYSSRLDIVRANSKSPLQRSLSAKCVS--------GTGQVSTCRLRKDQQ 270
           F  RN+    +      +    S+   Q++L  K             G+++  R +  ++
Sbjct: 277 FQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKK 336

Query: 271 AEDDEDDELDVTEEENFLK 289
               ED + +V + +  LK
Sbjct: 337 LHHTEDQKAEVEQHKETLK 355


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 32.7 bits (73), Expect = 0.38
 Identities = 46/188 (24%), Positives = 77/188 (40%), Gaps = 34/188 (18%)

Query: 3    RRTLENRNAQTKQ-LQTAVSNVEKHFGELCQIFAAYVRKTARLRDKADLLVNEINAYAAT 61
            +R LE R AQ ++ L+   SN+E        +     RKT        L V+ +NA  A 
Sbjct: 1731 KRRLEARIAQLEEELEEEQSNME--------LLNDRFRKTT-------LQVDTLNAELAA 1775

Query: 62   ETPHLKLGLMNFADEFAKLQDYRQAEVERLEAKVVEPLKTYGTIVKMKRDDLKATLTARN 121
            E               A+  D  + ++ER   ++   L+     VK K    KAT++A  
Sbjct: 1776 ER------------SAAQKSDNARQQLERQNKELKAKLQELEGAVKSK---FKATISALE 1820

Query: 122  REAKQLT-QLERTRQRNPSDRHVISQAETELQRAAMDASRTSRHLEETINNFER--QKMK 178
             +  QL  QLE+  +   +   ++ + E +L+   M      RH ++     E+   +MK
Sbjct: 1821 AKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMK 1880

Query: 179  DIKTIFSE 186
             +K    E
Sbjct: 1881 QLKRQLEE 1888


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.128    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,861,980
Number of Sequences: 37866
Number of extensions: 338721
Number of successful extensions: 2433
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 129
Number of HSP's that attempted gapping in prelim test: 2271
Number of HSP's gapped (non-prelim): 282
length of query: 289
length of database: 18,247,518
effective HSP length: 101
effective length of query: 188
effective length of database: 14,423,052
effective search space: 2711533776
effective search space used: 2711533776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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