Guide to the Human Genome
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Search of human proteins with 149944433

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149944433 hampin [Homo sapiens]
         (351 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149944433 hampin [Homo sapiens]                                    721   0.0  
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        50   3e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     45   7e-05
gi|32698714 hypothetical protein LOC284058 [Homo sapiens]              44   3e-04
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H...    40   0.003
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         39   0.005
gi|40217794 hypothetical protein LOC151050 [Homo sapiens]              39   0.005
gi|18034775 PHD finger protein 20 [Homo sapiens]                       39   0.007
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...    39   0.007
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    39   0.009
gi|149944516 tet oncogene family member 3 [Homo sapiens]               38   0.012
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         38   0.012
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         38   0.012
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              38   0.016
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    37   0.027
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s...    36   0.045
gi|29826341 calmodulin binding transcription activator 2 [Homo s...    36   0.045
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   36   0.059
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   36   0.059
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   36   0.059
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    36   0.059
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    36   0.059
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              36   0.059
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         36   0.059
gi|41281808 harmonin isoform b3 [Homo sapiens]                         35   0.077
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    35   0.077
gi|110349719 titin isoform N2-A [Homo sapiens]                         35   0.10 
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    35   0.10 
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         35   0.10 
gi|7706589 GNAS complex locus NESP55 [Homo sapiens]                    35   0.13 

>gi|149944433 hampin [Homo sapiens]
          Length = 351

 Score =  721 bits (1861), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MERRMQLVKKDNEKERHKLFQGYETEEREETELSEKIKLECQPELSETSQTLPPKPFSCG 60
           MERRMQLVKKDNEKERHKLFQGYETEEREETELSEKIKLECQPELSETSQTLPPKPFSCG
Sbjct: 1   MERRMQLVKKDNEKERHKLFQGYETEEREETELSEKIKLECQPELSETSQTLPPKPFSCG 60

Query: 61  RSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRS 120
           RSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRS
Sbjct: 61  RSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRS 120

Query: 121 QETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSP 180
           QETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSP
Sbjct: 121 QETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSP 180

Query: 181 LPLRESSPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDLLENLDDSVF 240
           LPLRESSPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDLLENLDDSVF
Sbjct: 181 LPLRESSPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDLLENLDDSVF 240

Query: 241 SKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKGIQESEPEVTSFFPEPDDVES 300
           SKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKGIQESEPEVTSFFPEPDDVES
Sbjct: 241 SKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKGIQESEPEVTSFFPEPDDVES 300

Query: 301 LMITPFLPVVAFGRPLPKLTPQNFELPWLDERSRCRLEIQKKQTPHRTCRK 351
           LMITPFLPVVAFGRPLPKLTPQNFELPWLDERSRCRLEIQKKQTPHRTCRK
Sbjct: 301 LMITPFLPVVAFGRPLPKLTPQNFELPWLDERSRCRLEIQKKQTPHRTCRK 351


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 46/168 (27%), Positives = 68/168 (40%), Gaps = 22/168 (13%)

Query: 36  KIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKK---LAPEFSKVK 92
           K K    P  S +S + PPK  S   S + H   SP    +  TP ++    +P+ ++  
Sbjct: 805 KAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQS 864

Query: 93  TKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKA 152
               + S  +  P   L      R   S  +P + +SS  TPPR S P +  S  PK KA
Sbjct: 865 VTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSS--TPPRQS-PSRSSSPQPKVKA 921

Query: 153 FSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESS---PKKEETVARC 197
             S  +             R H    SP P R +S   P++  +V+ C
Sbjct: 922 IISPRQ-------------RSHSGSSSPSPSRVTSRTTPRRSRSVSPC 956



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 42/166 (25%), Positives = 60/166 (36%), Gaps = 10/166 (6%)

Query: 40   ECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKT-----PVKKLAPEFSKV--K 92
            +  PE    +    P+    G S KG +  SP GS+  ++     P  + A   S+   +
Sbjct: 1619 DSSPEPKAPAPRALPRRSRSGSSSKG-RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE 1677

Query: 93   TKTPKHSPIKEEPCGSLSETVCKREL--RSQETPEKPRSSVDTPPRLSTPQKGPSTHPKE 150
             KT   +P +     S  E   K  L  RS+     P +   TPPR        S  P E
Sbjct: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAE 1737

Query: 151  KAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVAR 196
            K+ SS          T+    R   P P P  L+ S  +      R
Sbjct: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTR 1783



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 29/111 (26%), Positives = 43/111 (38%), Gaps = 8/111 (7%)

Query: 53  PPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSET 112
           PPKP+S  R     +  +P    ++K   +    E S  + +  K S  K+      SE+
Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKH----RSES 222

Query: 113 VCKRELRSQETPEKPRSSVDTP---PRLSTP-QKGPSTHPKEKAFSSEIED 159
             K+      TP+  R S D      R +TP  K    H    A S+   D
Sbjct: 223 ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSD 273



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 2/100 (2%)

Query: 53   PPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSET 112
            PP+  S  RS     +     S  +++     +P  S+V ++T         PC ++   
Sbjct: 904  PPRQ-SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESR 962

Query: 113  VCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKA 152
            +  R   S  +    +   +TPPR S      S +PK KA
Sbjct: 963  LLPRYSHSGSSSPDTKVKPETPPRQS-HSGSISPYPKVKA 1001



 Score = 28.5 bits (62), Expect = 9.4
 Identities = 57/253 (22%), Positives = 92/253 (36%), Gaps = 14/253 (5%)

Query: 46   SETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPI-KEE 104
            SE   +  PK        +     SP  + +  TP ++ +   S V  KT   +P+ +  
Sbjct: 1478 SECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS 1537

Query: 105  PCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTP--QKGPSTHPKEKAFSSEIEDLPY 162
              GS  E   K     QE  E   SS D+  +  TP  Q+  S    E    S +     
Sbjct: 1538 RSGSSQELDVKPSASPQERSESD-SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRS 1596

Query: 163  LSTTEMYLCRWHQPPPSPLPLRESSPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVEP 222
             S +   +    +  P      +SSP+ +    R L   S +G +S    PS       P
Sbjct: 1597 RSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPS-------P 1649

Query: 223  LRDPNPSDLLENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQRL--QLRMYKKKG 280
                +     E+   S  ++R ++   + K + R   +R R  R    L  + R+ ++  
Sbjct: 1650 EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR-RSSRSSPELTRKARLSRRSR 1708

Query: 281  IQESEPEVTSFFP 293
               S PE  S  P
Sbjct: 1709 SASSSPETRSRTP 1721



 Score = 28.5 bits (62), Expect = 9.4
 Identities = 26/101 (25%), Positives = 39/101 (38%), Gaps = 3/101 (2%)

Query: 99   SPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPP---RLSTPQKGPSTHPKEKAFSS 155
            SP+      S +  V +R  RS+    + RS   TPP   R S  +  P T  + ++ +S
Sbjct: 1916 SPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTS 1975

Query: 156  EIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVAR 196
             I      S T     R  +   SP+  R S  +      R
Sbjct: 1976 PITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRR 2016


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 69/325 (21%), Positives = 120/325 (36%), Gaps = 55/325 (16%)

Query: 10  KDNEKERHKLFQGYETEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRK 69
           K  EKE  K     ++ E+ ++   E+ K   + +  E  +   P         K   ++
Sbjct: 531 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE 590

Query: 70  SPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEE-------PCGSLSETVCKRELRSQE 122
                 E K+P K  +P   + K+     SP+KEE            +++  K E +S E
Sbjct: 591 EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE 650

Query: 123 -----------TPEKPRSSV----DTPPRLSTPQKGPSTHP-------KEKAFSSEIEDL 160
                      +PEK +S V     +P +  +P K  +  P       KE+A S E    
Sbjct: 651 KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS 710

Query: 161 PYLSTTEMYLCRWHQPPPSPLPLRE--------SSPKKEETVARCLMPSSVAGETSVLAV 212
           P     +        P  +  P++E         SP KEE  +     S    +T  +  
Sbjct: 711 PVKEEAK-------SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 763

Query: 213 PSWRDHSVEPLRDPN---PSDLLENLDDSVFSKRHAKLELDEKRR-------KRWDIQR- 261
           P  +  + E  R P    P      + + V S   AK  L E  +       K+ +++  
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823

Query: 262 IREQRILQRLQLRMYKKKGIQESEP 286
           ++E+   Q ++++   KK  +E  P
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAP 848



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 56/257 (21%), Positives = 93/257 (36%), Gaps = 42/257 (16%)

Query: 9   KKDNEKERHKLFQGYETEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKR 68
           K++      K  +  ++  +EE +  EK K   + +     + +P K           + 
Sbjct: 771 KEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK----------EEV 820

Query: 69  KSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPR 128
           KSP    E+   VK   P     + K P  +P  EE   S  E   K+E    +  EK  
Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEEEKAPA-TPKTEEKKDSKKEEAPKKEAPKPKVEEKKE 879

Query: 129 SSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSP 188
            +V+ P              K +A   E ED   + T E       +  P+ + ++E + 
Sbjct: 880 PAVEKP-----------KESKVEAKKEEAEDKKKVPTPE-------KEAPAKVEVKEDAK 921

Query: 189 KKEETV--------ARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDLLE---NLDD 237
            KE+T         A+   PS  A +    A P  +D   E  + P      E     DD
Sbjct: 922 PKEKTEVAKKEPDDAKAKEPSKPAEKKE--AAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979

Query: 238 SVFSKRHAKLELDEKRR 254
              SK  +K + ++  +
Sbjct: 980 KTLSKEPSKPKAEKAEK 996



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 43/208 (20%), Positives = 85/208 (40%), Gaps = 14/208 (6%)

Query: 26  EEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLA 85
           E+  ++ + E+ K   + +  E  +   P         K   ++      E K+P K+ A
Sbjct: 513 EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEA 572

Query: 86  PEFSKVKTKTPKHSPIKEE---PCGSLSETVCKRELRSQ-ETPEKPRSSV----DTPPRL 137
              ++VK+     SP KEE   P  + S    K  ++ + ++P + +S V     +P  +
Sbjct: 573 KSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEV 632

Query: 138 STPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVARC 197
            +P+K  S   KE+A S E    P     E    +  +   SP+     SP+K ++  + 
Sbjct: 633 KSPEKAKSP-TKEEAKSPEKAKSP-----EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA 686

Query: 198 LMPSSVAGETSVLAVPSWRDHSVEPLRD 225
              S    ++ V       + +  P+++
Sbjct: 687 EAKSPEKAKSPVKEEAKSPEKAKSPVKE 714



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 51/206 (24%), Positives = 80/206 (38%), Gaps = 26/206 (12%)

Query: 2   ERRMQLVKKDNEKER--HKLFQGYETEEREETELSEKIKLECQPELSETSQTLPP----- 54
           E+   +V++  E+ +   ++ +  E E +EE    E+   E + E  E     PP     
Sbjct: 451 EKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAA 510

Query: 55  KPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEE-------PCG 107
            P    +S    + KSP    E K+P K+ A   ++VK+     SP KEE          
Sbjct: 511 SPEKEAKSPVKEEAKSP---AEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP 567

Query: 108 SLSETVCKRELRSQETPEKP-RSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTT 166
              E     E++S E  + P +    +P    +P+K  S   KE+A S      P     
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP-VKEEAKSPAEAKSPVKEEA 626

Query: 167 EMYLCRWHQPPPSPLPLRESSPKKEE 192
           +        P     P +  SP KEE
Sbjct: 627 K-------SPAEVKSPEKAKSPTKEE 645



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 36/155 (23%), Positives = 65/155 (41%), Gaps = 10/155 (6%)

Query: 9    KKDNEKER--HKLFQGYETEEREE--TELSEKIKLECQPELSETSQTLPPKPFSCGRSGK 64
            KKD++KE    K     + EE++E   E  ++ K+E + E +E  + +P          +
Sbjct: 856  KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVE 915

Query: 65   GHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETP 124
              +   P    + KT V K  P+    K K P     K+E      +T  ++  + +E P
Sbjct: 916  VKEDAKP----KEKTEVAKKEPD--DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP 969

Query: 125  EKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIED 159
            +    + +    LS     P     EK+ S++ +D
Sbjct: 970  KTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKD 1004


>gi|32698714 hypothetical protein LOC284058 [Homo sapiens]
          Length = 1105

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 40/171 (23%), Positives = 63/171 (36%), Gaps = 38/171 (22%)

Query: 123 TPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPL- 181
           T  K    ++ PP +  P           +  SE+       ++  YL   H PP SPL 
Sbjct: 764 TAPKAERLLNPPPPVHDPNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLV 823

Query: 182 --------------------------PLRESSPKKEETVARCLMPSSVAGETSV------ 209
                                     P+R    +    +   ++P SVA  T V      
Sbjct: 824 RQLSTSSDSPAPASSSSQVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYK 883

Query: 210 -LAVPSWRDHSVEPLR--DPNPSDLLENLDDSVFSKRHAKLELDEKRRKRW 257
            +  PSWR+  ++ L+      ++ +E+L D+ F+  HAK E  E  R RW
Sbjct: 884 EILTPSWREVDLQSLKGSPDEENEEIEDLSDAAFAALHAKCE--EMERARW 932


>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
            sapiens]
          Length = 1447

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 40/173 (23%), Positives = 69/173 (39%), Gaps = 17/173 (9%)

Query: 1    MERRMQLVKKDNEK-ERHKLFQGYETEEREETELSEKIKLECQPELSETSQTLPPKPFSC 59
            M+   +LV++   K  +    +G+   E +E +  E+ +L+     +E  Q  PPK    
Sbjct: 1231 MDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKR 1290

Query: 60   GRS----GKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCK 115
            GR     G G  ++ P   T +K   KK  P   + + +  + S   E+   S    V +
Sbjct: 1291 GRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSR 1350

Query: 116  RELR------------SQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSE 156
            R  +            +Q TP+K R      P  S P+K       ++A + E
Sbjct: 1351 RAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKE 1403


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 39/136 (28%), Positives = 50/136 (36%), Gaps = 23/136 (16%)

Query: 13   EKERHKLFQGYETEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPF 72
            + ERH         ER  T LS   K E  P +S +S+T    P S     + H   S  
Sbjct: 1814 KSERHAPGSPSPKTERHST-LSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSS 1872

Query: 73   GSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVD 132
              TE+ +PV           TKT +HSP+        S T  +R       P  P    D
Sbjct: 1873 SKTEKHSPVSP--------STKTERHSPV--------SSTKTER-----HPPVSPSGKTD 1911

Query: 133  TPPRLSTPQKGPSTHP 148
              P +S P      HP
Sbjct: 1912 KRPPVS-PSGRTEKHP 1926


>gi|40217794 hypothetical protein LOC151050 [Homo sapiens]
          Length = 987

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 6/70 (8%)

Query: 210 LAVPSWRDHSVEPLRDPN-PSDLLENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRIL 268
           +  PSWR   ++PL + N   + +E+L D VFS RH K E  E+ + RW +    EQ   
Sbjct: 795 ILTPSWRMVVLQPLDEYNLGKEEIEDLSDEVFSLRHKKYE--EREQARWSLW---EQSKW 849

Query: 269 QRLQLRMYKK 278
            R   R Y K
Sbjct: 850 HRRNSRAYSK 859


>gi|18034775 PHD finger protein 20 [Homo sapiens]
          Length = 1012

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 4/62 (6%)

Query: 10  KDNEKERHKLFQGY---ETEEREETELSEKIKLECQPELSETSQ-TLPPKPFSCGRSGKG 65
           KD EK + K F+ +   + +++++ +   K +  C  E+S+TSQ   PPK F+  R G  
Sbjct: 523 KDKEKNKEKKFKEFVRVKPKKKKKKKKKTKPECPCSEEISDTSQEPSPPKAFAVTRCGSS 582

Query: 66  HK 67
           HK
Sbjct: 583 HK 584


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 40/154 (25%), Positives = 65/154 (42%), Gaps = 23/154 (14%)

Query: 26  EEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLA 85
           ++ EE E  EK K +   E++E  +T+ PK     +  K    +    S + K   KK  
Sbjct: 25  KQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKK--KAEPSEVDMNSPKSKKAKKKEE 82

Query: 86  PEFSKVKTKT----PKHSPIKEEPCGSLSETVCKRELRSQETPEKPR------------S 129
           P  + +  KT     K  PI+++   S ++ V K E  S+E  + P+             
Sbjct: 83  PSQNDISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSEEEIDAPKPKKMKKEKEMNGE 142

Query: 130 SVDTPPRLST--PQKGPSTHPKEKA---FSSEIE 158
           + +  P+L    P   P  +P E A    +SEIE
Sbjct: 143 TREKSPKLKNGFPHPEPDCNPSEAASEESNSEIE 176


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 50/195 (25%), Positives = 87/195 (44%), Gaps = 28/195 (14%)

Query: 120 SQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFS---SEIEDLPYLSTTEMYLCRWHQP 176
           S ETP   +    T  +   P++ P +  +++++    SE+++  +L   E+      QP
Sbjct: 421 SPETPSAGQQEAKTD-QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEEL------QP 473

Query: 177 PPSPLPLRESSPKKEETVARCLMPS-SVAGETSVLAVPSWRDHSV--------EPLR-DP 226
           P S  P   SSP     V R L           +L  P+    SV         PLR DP
Sbjct: 474 PRSKTP---SSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDP 530

Query: 227 NPSDL--LENL--DDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKGIQ 282
              +   LENL   +     R  K+E ++KRR+  +++  RE+R+ + LQ R   ++  +
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVE-EDKRRRLEEVKLKREERLRKVLQARERVEQMKE 589

Query: 283 ESEPEVTSFFPEPDD 297
           E + ++   F + D+
Sbjct: 590 EKKKQIEQKFAQIDE 604


>gi|149944516 tet oncogene family member 3 [Homo sapiens]
          Length = 1660

 Score = 38.1 bits (87), Expect = 0.012
 Identities = 28/115 (24%), Positives = 42/115 (36%), Gaps = 25/115 (21%)

Query: 103 EEPCGSLSETVCKRELRSQETPEKPRSSVDTPP-------------RLSTPQKGPSTHPK 149
           E+  GS S+ +     R +  P KP+  V+ P                 TP   P TH K
Sbjct: 329 EQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPAPSPVLQREAPTPSSEPDTHQK 388

Query: 150 EKA------------FSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEE 192
            +             F  ++ D  + + +E     W  PP SP+P     P KE+
Sbjct: 389 AQTALQQHLHHKRSLFLEQVHDTSFPAPSEPSAPGWWPPPSSPVPRLPDRPPKEK 443


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 38.1 bits (87), Expect = 0.012
 Identities = 62/314 (19%), Positives = 125/314 (39%), Gaps = 32/314 (10%)

Query: 2    ERRMQLVKKDNEKERHKLFQGYETEEREETELSEKIKL-ECQPELSETSQTLPPKPFSCG 60
            E+R Q+ +KD EK   K F+  +  + E     +K+ L EC  ++ E  +        C 
Sbjct: 800  EKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCH 859

Query: 61   RSGKGHKRKSPFGST-ERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELR 119
            + G+  K  +    T +R+   +K+  +  K K +  +H  + E     L E   K+   
Sbjct: 860  KEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERH--LAESKEKHLMEKKNKQSDN 917

Query: 120  SQETPEKPRSSVDTPPRLSTPQKG---------PSTHPKEKAFSSEIEDLPYLSTTEMYL 170
            S+ +  +   + +    L   +K           S H +E+  SS ++         + L
Sbjct: 918  SEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSL 977

Query: 171  CRWHQPPPSPLPLRESSPKKEETVAR---------------CLMPSSVAGETSVLAVPSW 215
                +  P   P  +   KK++ + R                L   S A +    + P+ 
Sbjct: 978  KEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPAS 1037

Query: 216  RDHSVEPLRDPNPSDLLENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQR--LQL 273
            +D   +  R  N  DL++   + + S +  ++E   K+ K   I++  ++R+  R  L+L
Sbjct: 1038 KDTRPKEKRLVN-DDLMQTSFERMLSLKDLEIEQWHKKHKE-KIKQKEKERLRNRNCLEL 1095

Query: 274  RMYKKKGIQESEPE 287
            ++  K+  + +  E
Sbjct: 1096 KIKDKEKTKHTPTE 1109


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 38.1 bits (87), Expect = 0.012
 Identities = 62/314 (19%), Positives = 125/314 (39%), Gaps = 32/314 (10%)

Query: 2    ERRMQLVKKDNEKERHKLFQGYETEEREETELSEKIKL-ECQPELSETSQTLPPKPFSCG 60
            E+R Q+ +KD EK   K F+  +  + E     +K+ L EC  ++ E  +        C 
Sbjct: 823  EKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCH 882

Query: 61   RSGKGHKRKSPFGST-ERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELR 119
            + G+  K  +    T +R+   +K+  +  K K +  +H  + E     L E   K+   
Sbjct: 883  KEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERH--LAESKEKHLMEKKNKQSDN 940

Query: 120  SQETPEKPRSSVDTPPRLSTPQKG---------PSTHPKEKAFSSEIEDLPYLSTTEMYL 170
            S+ +  +   + +    L   +K           S H +E+  SS ++         + L
Sbjct: 941  SEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSL 1000

Query: 171  CRWHQPPPSPLPLRESSPKKEETVAR---------------CLMPSSVAGETSVLAVPSW 215
                +  P   P  +   KK++ + R                L   S A +    + P+ 
Sbjct: 1001 KEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPAS 1060

Query: 216  RDHSVEPLRDPNPSDLLENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQR--LQL 273
            +D   +  R  N  DL++   + + S +  ++E   K+ K   I++  ++R+  R  L+L
Sbjct: 1061 KDTRPKEKRLVN-DDLMQTSFERMLSLKDLEIEQWHKKHKE-KIKQKEKERLRNRNCLEL 1118

Query: 274  RMYKKKGIQESEPE 287
            ++  K+  + +  E
Sbjct: 1119 KIKDKEKTKHTPTE 1132


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 37.7 bits (86), Expect = 0.016
 Identities = 34/148 (22%), Positives = 58/148 (39%), Gaps = 24/148 (16%)

Query: 9   KKDNEKERHKLFQGYETEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKR 68
           KK+ EK R KL  G E+  ++     ++ K  C+   S +S                   
Sbjct: 70  KKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSD----------------- 112

Query: 69  KSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPR 128
            S   S++ +   KK      K K ++ K S        S S+   K++ +S++  EK +
Sbjct: 113 -SSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEK 171

Query: 129 SSVDTPPRLSTPQKGPSTHPKEKAFSSE 156
                    S  +K   ++P +K  SSE
Sbjct: 172 DV------RSLSKKRKKSYPDDKPLSSE 193


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 37.0 bits (84), Expect = 0.027
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 32/199 (16%)

Query: 120 SQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFS---SEIEDLPYLSTTEMYLCRWHQP 176
           S ETP   +    T  +   P++ P +  +++++    SE+++  +L   E+      QP
Sbjct: 421 SPETPSAGQQEAKTD-QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEEL------QP 473

Query: 177 PPSPLPLRESSPKKEETVARCLMPS-SVAGETSVLAVPSWRDHSV--------EPLR-DP 226
           P S  P   SSP     V R L           +L  P+    SV         PLR DP
Sbjct: 474 PRSKTP---SSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDP 530

Query: 227 NPSDL------LENL--DDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKK 278
             S +      LENL   +     R  K+E ++KRR+  +++  RE+R+ + LQ R   +
Sbjct: 531 KCSFVEKERQRLENLRRKEEAEQLRRQKVE-EDKRRRLEEVKLKREERLRKVLQARERVE 589

Query: 279 KGIQESEPEVTSFFPEPDD 297
           +  +E + ++   F + D+
Sbjct: 590 QMKEEKKKQIEQKFAQIDE 608


>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
           sapiens]
          Length = 691

 Score = 36.2 bits (82), Expect = 0.045
 Identities = 30/114 (26%), Positives = 45/114 (39%), Gaps = 20/114 (17%)

Query: 121 QETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSP 180
           Q  P+ P  S   P + + PQ+ P    +  A +S+++  P     + +    +Q  PSP
Sbjct: 206 QPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSP 265

Query: 181 LPLRESSPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDLLEN 234
                S P+K         PS   G      +PS       PL  PNP  L+ N
Sbjct: 266 TQQSSSPPQK---------PSQSPGH----GLPS-------PLTPPNPLQLVNN 299


>gi|29826341 calmodulin binding transcription activator 2 [Homo
           sapiens]
          Length = 1202

 Score = 36.2 bits (82), Expect = 0.045
 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 6/72 (8%)

Query: 114 CKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRW 173
           C  EL+ QE       SV+ P  LS P   P T     +  SE+ D  +  T+       
Sbjct: 808 CLEELQRQEP------SVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPD 861

Query: 174 HQPPPSPLPLRE 185
             PPP+PLP  E
Sbjct: 862 GSPPPAPLPASE 873


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 35.8 bits (81), Expect = 0.059
 Identities = 41/174 (23%), Positives = 65/174 (37%), Gaps = 19/174 (10%)

Query: 69  KSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPR 128
           K P  +T +K   K+LAP  +K  T T    P    P G+           +  TP++P 
Sbjct: 584 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-----------APTTPKEPA 632

Query: 129 SSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLP--YLSTTEMYLCRWHQPPPSPLPLRES 186
            +    P  +TP+    T  KE A ++  +  P     TT           P+P   +E+
Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 692

Query: 187 SP--KKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDLLENLDDS 238
           +P   KE        P+    ET     P        P     P+ + ++ D+S
Sbjct: 693 APTTPKEPAPTTPKKPAPTTPETP----PPTTSEVSTPTTTKEPTTIHKSPDES 742



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 34/144 (23%), Positives = 54/144 (37%), Gaps = 11/144 (7%)

Query: 47  ETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPC 106
           E + T P +P            K P  +T +  P     P  +   TK P  +  KE   
Sbjct: 223 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--APTTTKEPAPTTPKEPAP 280

Query: 107 GSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTT 166
            +  E        +  TP++P  +    P  +TP++   T PKE   ++  E  P   TT
Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP---TT 337

Query: 167 EMYLCRWHQPPPSPLPLRESSPKK 190
           +         P +P     ++PKK
Sbjct: 338 K------EPAPTTPKEPAPTAPKK 355



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 39/173 (22%), Positives = 59/173 (34%), Gaps = 10/173 (5%)

Query: 25  TEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKL 84
           T  +E T  + K   E  P   E + T P +P                  T  K P    
Sbjct: 320 TTPKEPTPTTPK---EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376

Query: 85  APEFSKVKTKTPKHSPIKEEPCGSL--SETVCKRELRSQETP-----EKPRSSVDTPPRL 137
             E S    K P  +  K  P  +   + T  K    + + P     ++P  +    P  
Sbjct: 377 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 436

Query: 138 STPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKK 190
           +TP+K   T PKE A ++  E  P  +            P +P     ++PKK
Sbjct: 437 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 489



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 18/169 (10%)

Query: 30  ETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHK-----RKSPFGSTERKTPVKKL 84
           +T  ++  K+   P+++ T++ + P+P     S    +      K     T+  T   K 
Sbjct: 103 DTSTTQHNKVSTSPKIT-TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQ 161

Query: 85  APEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTP---PRLSTPQ 141
                K KT + K +        S+ +T  K    + +   KP    +T    P L+TP+
Sbjct: 162 TSTDGKEKTTSAKETQ-------SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 214

Query: 142 KGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKK 190
           +   T PKE A ++  E  P  +T +       +P P+      ++PK+
Sbjct: 215 EPTPTTPKEPASTTPKEPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKE 261



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 38/172 (22%), Positives = 62/172 (36%), Gaps = 17/172 (9%)

Query: 25  TEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKL 84
           T  +E    + K      P+    + T  P P +   +    K  +P       T  KK 
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP-------TTPKKP 309

Query: 85  APEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGP 144
           AP   K    T    P    P     E     +  +  TP++P  +    P  +TP++  
Sbjct: 310 APTTPKEPAPTTPKEPTPTTP----KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365

Query: 145 STHPKEKAFSSEIEDLPYL------STTEMYLCRWHQPPPSPLPLRESSPKK 190
            T PKE A ++  E  P        +TT+       +P P+      ++PK+
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 10/144 (6%)

Query: 69  KSPFGSTERKTPV---KKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPE 125
           K P  +T ++T     KKL P   +    T    P    P   L+ T    E  +  TPE
Sbjct: 472 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-EELAPTT--PEEPTPTTPE 528

Query: 126 KPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRE 185
           +P  +       +TP++   T PKE A ++  E  P   TT            +P  L+E
Sbjct: 529 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP---TTPKETAPTTPKGTAPTTLKE 585

Query: 186 SSPKKEETVA-RCLMPSSVAGETS 208
            +P   +  A + L P++    TS
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTS 609



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 6/96 (6%)

Query: 69  KSPFGSTERK---TPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPE 125
           K P  +T ++   T  K+ AP   K  T T   +P K  P           E  +  TPE
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPT---TPEKLAPTTPEKPAPTTPEELAPTTPE 520

Query: 126 KPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLP 161
           +P  +    P  +TP+      PKE A ++  E  P
Sbjct: 521 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 556



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 45/214 (21%), Positives = 69/214 (32%), Gaps = 25/214 (11%)

Query: 32  ELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKV 91
           E S  +  E   E  ET+ T           GK     +    +  KT  K LAP    +
Sbjct: 139 ETSLTVNKETTVETKETTTTNK----QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 194

Query: 92  KTKTPKHSPIKE----------------EPCGSLSETVCKRELRSQETPEKPRSSVDTPP 135
              TPK     +                EP  +  +      ++S  T  K  +   T  
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254

Query: 136 RLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVA 195
             +TP++   T  KE A ++  E  P  +T E         P +P     ++PKK     
Sbjct: 255 APTTPKEPAPTTTKEPAPTTPKEPAP-TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 313

Query: 196 RCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPS 229
               P   A  T     P+         ++P P+
Sbjct: 314 ----PKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 343


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 35.8 bits (81), Expect = 0.059
 Identities = 41/174 (23%), Positives = 65/174 (37%), Gaps = 19/174 (10%)

Query: 69  KSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPR 128
           K P  +T +K   K+LAP  +K  T T    P    P G+           +  TP++P 
Sbjct: 625 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-----------APTTPKEPA 673

Query: 129 SSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLP--YLSTTEMYLCRWHQPPPSPLPLRES 186
            +    P  +TP+    T  KE A ++  +  P     TT           P+P   +E+
Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 733

Query: 187 SP--KKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDLLENLDDS 238
           +P   KE        P+    ET     P        P     P+ + ++ D+S
Sbjct: 734 APTTPKEPAPTTPKKPAPTTPETP----PPTTSEVSTPTTTKEPTTIHKSPDES 783



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 34/144 (23%), Positives = 54/144 (37%), Gaps = 11/144 (7%)

Query: 47  ETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPC 106
           E + T P +P            K P  +T +  P     P  +   TK P  +  KE   
Sbjct: 264 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--APTTTKEPAPTTPKEPAP 321

Query: 107 GSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTT 166
            +  E        +  TP++P  +    P  +TP++   T PKE   ++  E  P   TT
Sbjct: 322 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP---TT 378

Query: 167 EMYLCRWHQPPPSPLPLRESSPKK 190
           +         P +P     ++PKK
Sbjct: 379 K------EPAPTTPKEPAPTAPKK 396



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 39/173 (22%), Positives = 59/173 (34%), Gaps = 10/173 (5%)

Query: 25  TEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKL 84
           T  +E T  + K   E  P   E + T P +P                  T  K P    
Sbjct: 361 TTPKEPTPTTPK---EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417

Query: 85  APEFSKVKTKTPKHSPIKEEPCGSL--SETVCKRELRSQETP-----EKPRSSVDTPPRL 137
             E S    K P  +  K  P  +   + T  K    + + P     ++P  +    P  
Sbjct: 418 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 477

Query: 138 STPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKK 190
           +TP+K   T PKE A ++  E  P  +            P +P     ++PKK
Sbjct: 478 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 530



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 18/169 (10%)

Query: 30  ETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHK-----RKSPFGSTERKTPVKKL 84
           +T  ++  K+   P+++ T++ + P+P     S    +      K     T+  T   K 
Sbjct: 144 DTSTTQHNKVSTSPKIT-TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQ 202

Query: 85  APEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTP---PRLSTPQ 141
                K KT + K +        S+ +T  K    + +   KP    +T    P L+TP+
Sbjct: 203 TSTDGKEKTTSAKETQ-------SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 255

Query: 142 KGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKK 190
           +   T PKE A ++  E  P  +T +       +P P+      ++PK+
Sbjct: 256 EPTPTTPKEPASTTPKEPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKE 302



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 38/172 (22%), Positives = 62/172 (36%), Gaps = 17/172 (9%)

Query: 25  TEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKL 84
           T  +E    + K      P+    + T  P P +   +    K  +P       T  KK 
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP-------TTPKKP 350

Query: 85  APEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGP 144
           AP   K    T    P    P     E     +  +  TP++P  +    P  +TP++  
Sbjct: 351 APTTPKEPAPTTPKEPTPTTP----KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406

Query: 145 STHPKEKAFSSEIEDLPYL------STTEMYLCRWHQPPPSPLPLRESSPKK 190
            T PKE A ++  E  P        +TT+       +P P+      ++PK+
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 10/144 (6%)

Query: 69  KSPFGSTERKTPV---KKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPE 125
           K P  +T ++T     KKL P   +    T    P    P   L+ T    E  +  TPE
Sbjct: 513 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-EELAPTT--PEEPTPTTPE 569

Query: 126 KPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRE 185
           +P  +       +TP++   T PKE A ++  E  P   TT            +P  L+E
Sbjct: 570 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP---TTPKETAPTTPKGTAPTTLKE 626

Query: 186 SSPKKEETVA-RCLMPSSVAGETS 208
            +P   +  A + L P++    TS
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTS 650



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 6/96 (6%)

Query: 69  KSPFGSTERK---TPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPE 125
           K P  +T ++   T  K+ AP   K  T T   +P K  P           E  +  TPE
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPT---TPEKLAPTTPEKPAPTTPEELAPTTPE 561

Query: 126 KPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLP 161
           +P  +    P  +TP+      PKE A ++  E  P
Sbjct: 562 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 597



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 45/214 (21%), Positives = 69/214 (32%), Gaps = 25/214 (11%)

Query: 32  ELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKV 91
           E S  +  E   E  ET+ T           GK     +    +  KT  K LAP    +
Sbjct: 180 ETSLTVNKETTVETKETTTTNK----QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 235

Query: 92  KTKTPKHSPIKE----------------EPCGSLSETVCKRELRSQETPEKPRSSVDTPP 135
              TPK     +                EP  +  +      ++S  T  K  +   T  
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295

Query: 136 RLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVA 195
             +TP++   T  KE A ++  E  P  +T E         P +P     ++PKK     
Sbjct: 296 APTTPKEPAPTTTKEPAPTTPKEPAP-TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 354

Query: 196 RCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPS 229
               P   A  T     P+         ++P P+
Sbjct: 355 ----PKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 384


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 35.8 bits (81), Expect = 0.059
 Identities = 41/174 (23%), Positives = 65/174 (37%), Gaps = 19/174 (10%)

Query: 69  KSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPR 128
           K P  +T +K   K+LAP  +K  T T    P    P G+           +  TP++P 
Sbjct: 677 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-----------APTTPKEPA 725

Query: 129 SSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLP--YLSTTEMYLCRWHQPPPSPLPLRES 186
            +    P  +TP+    T  KE A ++  +  P     TT           P+P   +E+
Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785

Query: 187 SP--KKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDLLENLDDS 238
           +P   KE        P+    ET     P        P     P+ + ++ D+S
Sbjct: 786 APTTPKEPAPTTPKKPAPTTPETP----PPTTSEVSTPTTTKEPTTIHKSPDES 835



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 34/144 (23%), Positives = 54/144 (37%), Gaps = 11/144 (7%)

Query: 47  ETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPC 106
           E + T P +P            K P  +T +  P     P  +   TK P  +  KE   
Sbjct: 316 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--APTTTKEPAPTTPKEPAP 373

Query: 107 GSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTT 166
            +  E        +  TP++P  +    P  +TP++   T PKE   ++  E  P   TT
Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP---TT 430

Query: 167 EMYLCRWHQPPPSPLPLRESSPKK 190
           +         P +P     ++PKK
Sbjct: 431 K------EPAPTTPKEPAPTAPKK 448



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 47/213 (22%), Positives = 82/213 (38%), Gaps = 34/213 (15%)

Query: 2   ERRMQLVKKDNEKERHK----------------LFQGYETEEREETELSEKIKLECQPEL 45
           E + +L  KDN+K R K                L  G       +T  ++  K+   P++
Sbjct: 152 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 211

Query: 46  SETSQTLPPKPFSCGRSGKGHK-----RKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSP 100
           + T++ + P+P     S    +      K     T+  T   K      K KT + K + 
Sbjct: 212 T-TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ 270

Query: 101 IKEEPCGSLSETVCKRELRSQETPEKPRSSVDTP---PRLSTPQKGPSTHPKEKAFSSEI 157
                  S+ +T  K    + +   KP    +T    P L+TP++   T PKE A ++  
Sbjct: 271 -------SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK 323

Query: 158 EDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKK 190
           E  P  +T +       +P P+      ++PK+
Sbjct: 324 EPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKE 354



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 39/173 (22%), Positives = 59/173 (34%), Gaps = 10/173 (5%)

Query: 25  TEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKL 84
           T  +E T  + K   E  P   E + T P +P                  T  K P    
Sbjct: 413 TTPKEPTPTTPK---EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469

Query: 85  APEFSKVKTKTPKHSPIKEEPCGSL--SETVCKRELRSQETP-----EKPRSSVDTPPRL 137
             E S    K P  +  K  P  +   + T  K    + + P     ++P  +    P  
Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 529

Query: 138 STPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKK 190
           +TP+K   T PKE A ++  E  P  +            P +P     ++PKK
Sbjct: 530 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 582



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 38/172 (22%), Positives = 62/172 (36%), Gaps = 17/172 (9%)

Query: 25  TEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKL 84
           T  +E    + K      P+    + T  P P +   +    K  +P       T  KK 
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP-------TTPKKP 402

Query: 85  APEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGP 144
           AP   K    T    P    P     E     +  +  TP++P  +    P  +TP++  
Sbjct: 403 APTTPKEPAPTTPKEPTPTTP----KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458

Query: 145 STHPKEKAFSSEIEDLPYL------STTEMYLCRWHQPPPSPLPLRESSPKK 190
            T PKE A ++  E  P        +TT+       +P P+      ++PK+
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 510



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 10/144 (6%)

Query: 69  KSPFGSTERKTPV---KKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPE 125
           K P  +T ++T     KKL P   +    T    P    P   L+ T    E  +  TPE
Sbjct: 565 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-EELAPTT--PEEPTPTTPE 621

Query: 126 KPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRE 185
           +P  +       +TP++   T PKE A ++  E  P   TT            +P  L+E
Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP---TTPKETAPTTPKGTAPTTLKE 678

Query: 186 SSPKKEETVA-RCLMPSSVAGETS 208
            +P   +  A + L P++    TS
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTS 702



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 6/96 (6%)

Query: 69  KSPFGSTERK---TPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPE 125
           K P  +T ++   T  K+ AP   K  T T   +P K  P           E  +  TPE
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPT---TPEKLAPTTPEKPAPTTPEELAPTTPE 613

Query: 126 KPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLP 161
           +P  +    P  +TP+      PKE A ++  E  P
Sbjct: 614 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 649



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 45/214 (21%), Positives = 69/214 (32%), Gaps = 25/214 (11%)

Query: 32  ELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKV 91
           E S  +  E   E  ET+ T           GK     +    +  KT  K LAP    +
Sbjct: 232 ETSLTVNKETTVETKETTTTNK----QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 287

Query: 92  KTKTPKHSPIKE----------------EPCGSLSETVCKRELRSQETPEKPRSSVDTPP 135
              TPK     +                EP  +  +      ++S  T  K  +   T  
Sbjct: 288 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 347

Query: 136 RLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVA 195
             +TP++   T  KE A ++  E  P  +T E         P +P     ++PKK     
Sbjct: 348 APTTPKEPAPTTTKEPAPTTPKEPAP-TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 406

Query: 196 RCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPS 229
               P   A  T     P+         ++P P+
Sbjct: 407 ----PKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 436


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 35.8 bits (81), Expect = 0.059
 Identities = 41/174 (23%), Positives = 65/174 (37%), Gaps = 19/174 (10%)

Query: 69  KSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPR 128
           K P  +T +K   K+LAP  +K  T T    P    P G+           +  TP++P 
Sbjct: 718 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-----------APTTPKEPA 766

Query: 129 SSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLP--YLSTTEMYLCRWHQPPPSPLPLRES 186
            +    P  +TP+    T  KE A ++  +  P     TT           P+P   +E+
Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826

Query: 187 SP--KKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDLLENLDDS 238
           +P   KE        P+    ET     P        P     P+ + ++ D+S
Sbjct: 827 APTTPKEPAPTTPKKPAPTTPETP----PPTTSEVSTPTTTKEPTTIHKSPDES 876



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 34/144 (23%), Positives = 54/144 (37%), Gaps = 11/144 (7%)

Query: 47  ETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPC 106
           E + T P +P            K P  +T +  P     P  +   TK P  +  KE   
Sbjct: 357 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--APTTTKEPAPTTPKEPAP 414

Query: 107 GSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTT 166
            +  E        +  TP++P  +    P  +TP++   T PKE   ++  E  P   TT
Sbjct: 415 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP---TT 471

Query: 167 EMYLCRWHQPPPSPLPLRESSPKK 190
           +         P +P     ++PKK
Sbjct: 472 K------EPAPTTPKEPAPTAPKK 489



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 47/213 (22%), Positives = 82/213 (38%), Gaps = 34/213 (15%)

Query: 2   ERRMQLVKKDNEKERHK----------------LFQGYETEEREETELSEKIKLECQPEL 45
           E + +L  KDN+K R K                L  G       +T  ++  K+   P++
Sbjct: 193 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 252

Query: 46  SETSQTLPPKPFSCGRSGKGHK-----RKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSP 100
           + T++ + P+P     S    +      K     T+  T   K      K KT + K + 
Sbjct: 253 T-TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ 311

Query: 101 IKEEPCGSLSETVCKRELRSQETPEKPRSSVDTP---PRLSTPQKGPSTHPKEKAFSSEI 157
                  S+ +T  K    + +   KP    +T    P L+TP++   T PKE A ++  
Sbjct: 312 -------SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK 364

Query: 158 EDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKK 190
           E  P  +T +       +P P+      ++PK+
Sbjct: 365 EPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKE 395



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 39/173 (22%), Positives = 59/173 (34%), Gaps = 10/173 (5%)

Query: 25  TEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKL 84
           T  +E T  + K   E  P   E + T P +P                  T  K P    
Sbjct: 454 TTPKEPTPTTPK---EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510

Query: 85  APEFSKVKTKTPKHSPIKEEPCGSL--SETVCKRELRSQETP-----EKPRSSVDTPPRL 137
             E S    K P  +  K  P  +   + T  K    + + P     ++P  +    P  
Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 570

Query: 138 STPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKK 190
           +TP+K   T PKE A ++  E  P  +            P +P     ++PKK
Sbjct: 571 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 623



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 38/172 (22%), Positives = 62/172 (36%), Gaps = 17/172 (9%)

Query: 25  TEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKL 84
           T  +E    + K      P+    + T  P P +   +    K  +P       T  KK 
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP-------TTPKKP 443

Query: 85  APEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGP 144
           AP   K    T    P    P     E     +  +  TP++P  +    P  +TP++  
Sbjct: 444 APTTPKEPAPTTPKEPTPTTP----KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499

Query: 145 STHPKEKAFSSEIEDLPYL------STTEMYLCRWHQPPPSPLPLRESSPKK 190
            T PKE A ++  E  P        +TT+       +P P+      ++PK+
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 551



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 10/144 (6%)

Query: 69  KSPFGSTERKTPV---KKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPE 125
           K P  +T ++T     KKL P   +    T    P    P   L+ T    E  +  TPE
Sbjct: 606 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-EELAPTT--PEEPTPTTPE 662

Query: 126 KPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRE 185
           +P  +       +TP++   T PKE A ++  E  P   TT            +P  L+E
Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP---TTPKETAPTTPKGTAPTTLKE 719

Query: 186 SSPKKEETVA-RCLMPSSVAGETS 208
            +P   +  A + L P++    TS
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTS 743



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 6/96 (6%)

Query: 69  KSPFGSTERK---TPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPE 125
           K P  +T ++   T  K+ AP   K  T T   +P K  P           E  +  TPE
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPT---TPEKLAPTTPEKPAPTTPEELAPTTPE 654

Query: 126 KPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLP 161
           +P  +    P  +TP+      PKE A ++  E  P
Sbjct: 655 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 690



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 45/214 (21%), Positives = 69/214 (32%), Gaps = 25/214 (11%)

Query: 32  ELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKV 91
           E S  +  E   E  ET+ T           GK     +    +  KT  K LAP    +
Sbjct: 273 ETSLTVNKETTVETKETTTTNK----QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 328

Query: 92  KTKTPKHSPIKE----------------EPCGSLSETVCKRELRSQETPEKPRSSVDTPP 135
              TPK     +                EP  +  +      ++S  T  K  +   T  
Sbjct: 329 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 388

Query: 136 RLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVA 195
             +TP++   T  KE A ++  E  P  +T E         P +P     ++PKK     
Sbjct: 389 APTTPKEPAPTTTKEPAPTTPKEPAP-TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 447

Query: 196 RCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPS 229
               P   A  T     P+         ++P P+
Sbjct: 448 ----PKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 477


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 35.8 bits (81), Expect = 0.059
 Identities = 51/244 (20%), Positives = 94/244 (38%), Gaps = 13/244 (5%)

Query: 46  SETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEF---SKVKTKTPKHS-PI 101
           S +S T   KP    +  K HK K    S E K+  K+ + +    SK  +K PK + P+
Sbjct: 186 SSSSSTSFSKPH---KLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPL 242

Query: 102 KEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLP 161
           KEE           + +  +  P+    ++ +      P K P     E+  + + +   
Sbjct: 243 KEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKK-- 300

Query: 162 YLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVE 221
             S++E     +   PP  L L  S+ KK+      +    V  E+             +
Sbjct: 301 --SSSEALFKSFSSAPP--LILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFD 356

Query: 222 PLRDPNPSDLLENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKGI 281
            + DPN SD+ EN+     S++ +           +   + R+Q  L+ +   ++     
Sbjct: 357 DIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNE 416

Query: 282 QESE 285
           +ES+
Sbjct: 417 EESD 420


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 35.8 bits (81), Expect = 0.059
 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 35/117 (29%)

Query: 124 PEKPRSSVDTPPRLSTP----------QKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRW 173
           P KPRS     P L+ P             P + P  +   + +++ P +S  +      
Sbjct: 674 PSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQ------ 727

Query: 174 HQPPPSPLPLRESSP---KKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPN 227
             PPPSP P     P   KK E V                  PS  + + EPL+DPN
Sbjct: 728 -SPPPSPPPSYHPPPPPTKKPEVVVEA---------------PSASETAEEPLQDPN 768


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 35.8 bits (81), Expect = 0.059
 Identities = 40/186 (21%), Positives = 71/186 (38%), Gaps = 32/186 (17%)

Query: 9   KKDNEKERHKLFQGYETEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKR 68
           KK+ EKE+ +      ++ R  T    +     +P     S++   + +S  R     +R
Sbjct: 266 KKEKEKEKTRPRSRSRSKSRSRTR--SRSPSHTRPRRRHRSRS---RSYSPRRRPSPRRR 320

Query: 69  KSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLS-ETVCKRELRSQETPEKP 127
            SP     R+TP +++ P     ++++P     +     SLS  +      RS+  P+KP
Sbjct: 321 PSP----RRRTPPRRMPPPPRHRRSRSPVRR--RRRSSASLSGSSSSSSSSRSRSPPKKP 374

Query: 128 RSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESS 187
                +PPR  T +  PS  P  +                        PP +P P    S
Sbjct: 375 PKRTSSPPR-KTRRLSPSASPPRRRHRP-------------------SPPATPPPKTRHS 414

Query: 188 PKKEET 193
           P  +++
Sbjct: 415 PTPQQS 420



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 43/182 (23%), Positives = 66/182 (36%), Gaps = 21/182 (11%)

Query: 62  SGKGHKRKSPFGSTERKTPVKKLAPEFSKVKT-------KTPKHSPIKEEPCGSLSETVC 114
           S +G +R+SP     R+      AP   + +T       +TP   P +  P         
Sbjct: 541 SPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPI 600

Query: 115 KRELRSQETPEKPRSSVDTPP-RLSTPQKGP------STHPKEKAFSSEIEDLPYLSTTE 167
           +R       P++  +S   PP R ++P   P      S  PK+++        P LS+  
Sbjct: 601 QRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH 660

Query: 168 MYLCRWHQPPPSPLPLRESSPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPN 227
               +   P  S    R   P K  + +    P   A +TS    P  R  S  P R  +
Sbjct: 661 R---KGSSPSRSTREARSPQPNKRHSPS----PRPRAPQTSSSPPPVRRGASSSPQRRQS 713

Query: 228 PS 229
           PS
Sbjct: 714 PS 715


>gi|41281808 harmonin isoform b3 [Homo sapiens]
          Length = 899

 Score = 35.4 bits (80), Expect = 0.077
 Identities = 61/252 (24%), Positives = 91/252 (36%), Gaps = 65/252 (25%)

Query: 2   ERRMQLVKKDNEKERHKLFQGYETEEREETELSEKIKL----ECQPELSETSQ------- 50
           + + ++++K+ + + ++L Q     ERE+ E SEKI+      CQ  L + S        
Sbjct: 451 KEKEEMLEKEKQLKINRLAQEVSETEREDLEESEKIQYWVERLCQTRLEQISSADNEISE 510

Query: 51  --TLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGS 108
             T PP P           R+   G     T +  +  +      KTP   P+   P   
Sbjct: 511 MTTGPPPPPPSVSPLAPPLRRFAGGLHLHTTDLDDIPLDMFYYPPKTPSALPVMPHP--- 567

Query: 109 LSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEM 168
                          P  P   V  PP L  P  G        A SS     P++  T  
Sbjct: 568 --------------PPSNPPHKVPAPPVL--PLSG-----HVSASSS-----PWVQRT-- 599

Query: 169 YLCRWHQPPPSPLPLRESSPKKEETVARCLMPSSV----------AGETSVLAVPSW--R 216
                  PPP P+P   S P ++ T  R L PS++           G+T    V  W  +
Sbjct: 600 -------PPPIPIPPPPSVPTQDLTPTRPL-PSALEEALSNHPFRTGDTG-NPVEDWEAK 650

Query: 217 DHSVEPLRDPNP 228
           +HS +P   P P
Sbjct: 651 NHSGKPTNSPVP 662


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 35.4 bits (80), Expect = 0.077
 Identities = 51/187 (27%), Positives = 69/187 (36%), Gaps = 27/187 (14%)

Query: 29  EETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVK-KLAPE 87
           EE  LS + +   +P LS      P +P  C    + H      G      P +  L+P+
Sbjct: 757 EEPHLSPQAE---EPHLSPQ----PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQ 809

Query: 88  FSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPR-SSVDTPPRLSTPQKGPST 146
                T+ P  SP+ EEPC S          +S+E    PR       P L  P   P  
Sbjct: 810 -----TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP 864

Query: 147 H--PKEKAFSSEIEDLPYLSTT----------EMYLCRWHQPPPSPLPLR-ESSPKKEET 193
              P+E       E+LP               E  L    +PP SPLP     SP  E +
Sbjct: 865 EKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPS 924

Query: 194 VARCLMP 200
           ++  LMP
Sbjct: 925 LSPQLMP 931



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 34/120 (28%), Positives = 46/120 (38%), Gaps = 8/120 (6%)

Query: 96  PKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTP-QKGP-STHPKEKAF 153
           P+ SP+   P  S +    +    S    E P S +     LS P ++ P S  P+E   
Sbjct: 444 PEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503

Query: 154 SSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVARCLMPSSVAGETSVLAVP 213
           S   E  P+    E  L    + PPSP      SP  E +      P S   E S L+ P
Sbjct: 504 SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS------PLSPPFEESPLSPP 557



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 35/123 (28%), Positives = 49/123 (39%), Gaps = 27/123 (21%)

Query: 176  PPPSPLPLRESSPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDLLENL 235
            PPPSPL    +SP  E  V    +P+    E  V                P+P  L  + 
Sbjct: 4916 PPPSPLAPSPASPPTEPLVE---LPTEPLAEPPV----------------PSPLPLASSP 4956

Query: 236  DDSVFSKRHAKLELDEKRR----KRWDIQRIREQRILQRLQLRMYKKKGIQESEPEVTSF 291
            + +    R    E  E  R    K+W  + +R +R+  RL L + K  G QE E EV  F
Sbjct: 4957 ESARPKPRARPPEEGEDSRPPRLKKW--KGVRWKRL--RLLLTIQKGSGRQEDEREVAEF 5012

Query: 292  FPE 294
              +
Sbjct: 5013 MEQ 5015



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 69/281 (24%), Positives = 99/281 (35%), Gaps = 54/281 (19%)

Query: 69  KSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPR 128
           +SP      ++P     PE S++ +  P+ SP    P  S +    +  L S    E P 
Sbjct: 668 ESPLSPPPEESPTSP-PPEASRL-SPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL 725

Query: 129 SSVDTPPRLSTPQKGP-----------STHPKEKAFSSEIEDLPYLSTTEMYLCRWHQP- 176
             +   P+L    +GP           S  P+E   S + E+ P+LS      C    P 
Sbjct: 726 LPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEE-PHLSPQPEEPCLCAVPE 784

Query: 177 PPSPLPLRES---SPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNP--SDL 231
            P   P  E    SP+ EE     L  S    E  +  VP       EP   P P  S L
Sbjct: 785 EPHLSPQAEGPHLSPQPEE-----LHLSPQTEEPHLSPVPE------EPCLSPQPEESHL 833

Query: 232 LENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKGIQE----SEPE 287
               ++   S R  +  L  +               L++  L    +K  +E      PE
Sbjct: 834 SPQSEEPCLSPRPEESHLSPE---------------LEKPPLSPRPEKPPEEPGQCPAPE 878

Query: 288 VTSFFPEPDDVESLMITPFLPVVAFGRP-LPKLTPQNFELP 327
               FP P +     ++P L   A   P  P L+P   ELP
Sbjct: 879 ELPLFPPPGEPS---LSPLLGEPALSEPGEPPLSPLPEELP 916


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 35.0 bits (79), Expect = 0.10
 Identities = 71/340 (20%), Positives = 133/340 (39%), Gaps = 62/340 (18%)

Query: 23    YETEEREETELSEK---IKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKT 79
             Y  EE EE    E+    + E  P +      +P KP          + K P    ++K 
Sbjct: 9921  YLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVP--------EEKKPVPVPKKKE 9972

Query: 80    PVKKLAPEF-SKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETP-------EKPRSSV 131
                   PE   K + K P   P KE+P  +    V K+ +  ++ P       E P + V
Sbjct: 9973  APPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKV 10032

Query: 132   DTPPRLSTPQKG-PSTHPKE-KAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPK 189
                P+   P+K  P   PK+ +A  +++ ++P     E       +  P+P+P +  +P 
Sbjct: 10033 PEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPE-------EKKPTPVPKKVEAPP 10085

Query: 190   KEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDLLENLDDSVFSKRHAKLEL 249
              +                    VP  R+    P+  P   ++L   ++ +  +     E 
Sbjct: 10086 PK--------------------VPKKREPVPVPVALPQEEEVL--FEEEIVPEEEVLPEE 10123

Query: 250   DEKRRKRWDIQRIREQRILQRLQLRMYKKKGIQESE--PEVTSFFPEPDDVESLMITPFL 307
             +E   +  ++    E+ + +  ++   +++   E E  PE   F PE + +    + P +
Sbjct: 10124 EEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPE--VKPKV 10181

Query: 308   PVVAFGRPLP----KLTPQNFELPWLDERSRCRL-EIQKK 342
             PV A   P+P    K+T +   +P  +E    ++ E+ KK
Sbjct: 10182 PVPA---PVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKK 10218



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 50/204 (24%), Positives = 77/204 (37%), Gaps = 36/204 (17%)

Query: 26    EEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLA 85
             +E E  ++ EK KL+ +P         PP P +  +     K        ++K P K   
Sbjct: 10864 KEPEPEKVIEKPKLKPRP---------PPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQV 10914

Query: 86    PEF------------SKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDT 133
             PE              KV+   P+  P  +E      E V K  LR +   E+P+     
Sbjct: 10915 PEKVELTPLKVPGGEKKVRKLLPERKPEPKE------EVVLKSVLRKRPEEEEPKVE--- 10965

Query: 134   PPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQ----PPPSPLPLRESSPK 189
             P +L   +K     P       E+E +P ++  E  +    +     P  PLP  E  PK
Sbjct: 10966 PKKLEKVKKPAVPEPPPPKPVEEVE-VPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPK 11024

Query: 190   KEETVARCLMPSSVAGETSVLAVP 213
              E  V + + P  V  E + +A P
Sbjct: 11025 PEAEV-KTIKPPPVEPEPTPIAAP 11047



 Score = 32.3 bits (72), Expect = 0.65
 Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 13/125 (10%)

Query: 71    PFGSTERKTPVKKLAPEFSK--VKTKTPKHSPIK--EEPCGSLSETVCKRELRSQETPEK 126
             P    +   P KK  PE     V  K P+  P+K  E P   + E   K  L   + PE 
Sbjct: 10687 PAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEK--KVPLVVPKKPEA 10744

Query: 127   PRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRES 186
             P + V   P+   P+K  +   K +   +++ ++P     E       + P  P+P R  
Sbjct: 10745 PPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLE-------EKPAVPVPERAE 10797

Query: 187   SPKKE 191
             SP  E
Sbjct: 10798 SPPPE 10802



 Score = 32.0 bits (71), Expect = 0.85
 Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 25/140 (17%)

Query: 25    TEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKL 84
             TEE EE  +SE+   E  P + E  +  PP      R  +  K+  P    E  TPV K 
Sbjct: 10238 TEEPEEEPISEEEIPEEPPSIEEVEEVAPP------RVPEVIKKAVP----EAPTPVPK- 10286

Query: 85    APEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPR----SSVDTPPRLSTP 140
                    K + P     K+ P   +   V K+E    + PE P+      V  P + + P
Sbjct: 10287 -------KVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVP 10339

Query: 141   QKGPSTHPKEK---AFSSEI 157
                  T  +EK   AF  E+
Sbjct: 10340 PAKGRTVLEEKVSVAFRQEV 10359



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 47/205 (22%), Positives = 72/205 (35%), Gaps = 40/205 (19%)

Query: 24    ETEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRK----SPFGSTERKT 79
             E E + E +  EK+K    PE        PPKP          KR+     P    E K 
Sbjct: 10959 EEEPKVEPKKLEKVKKPAVPEPP------PPKPVEEVEVPTVTKRERKIPEPTKVPEIKP 11012

Query: 80    PVKKLAPEFS---KVKTKTPKHSPIKEEPC-----------GSLSETVCKRELRSQE--- 122
              +   APE     + + KT K  P++ EP            G  +E    +E  ++    
Sbjct: 11013 AIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGP 11072

Query: 123   ---TPEKPRSSVDTPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPS 179
                 P+K  S ++   R   P  G    P E  F+ +++ +P     E+           
Sbjct: 11073 IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEI----------K 11122

Query: 180   PLPLRESSPKKEETVARCLMPSSVA 204
              + L ES       +  CL+  S A
Sbjct: 11123 DIILTESEFVGSSAIFECLVSPSTA 11147



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 47/216 (21%), Positives = 74/216 (34%), Gaps = 40/216 (18%)

Query: 14   KERHKLFQGY-ETEEREETELSEKIKLECQPELSETS-----------QTLPPKPFSCGR 61
            +E ++  +GY E EE  E    E+  ++ Q E+ E S           +  PP P    +
Sbjct: 9124 QEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKK 9183

Query: 62   SGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEE------PCGSLSETVCK 115
                   K+     E K  V K+     K+  + P  +P++EE      P     + V  
Sbjct: 9184 PVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVIS 9243

Query: 116  RELRSQETPEKPRSSVDTP-----------------PRLSTPQKGPSTHPKEKAFSSEIE 158
             E     +  +   SV  P                  R+  P K P     EK    E+ 
Sbjct: 9244 EEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPEL--PEKPAPEEVA 9301

Query: 159  DLPYLSTTEMYLCRWHQPPPSPLPLRESS---PKKE 191
             +P     E    +  + P  P+P  +     PKKE
Sbjct: 9302 PVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKE 9337



 Score = 28.5 bits (62), Expect = 9.4
 Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 3/97 (3%)

Query: 47  ETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPC 106
           +T   +PPKP S   +      K+     +  +P++        V+  TP  SP++    
Sbjct: 252 KTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTP--SPVRSVSP 309

Query: 107 GSLSETVCKRELRSQETPEKPR-SSVDTPPRLSTPQK 142
            +   T   R +RS     K + S+V T P +  P K
Sbjct: 310 AARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWK 346


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 35.0 bits (79), Expect = 0.10
 Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 12/107 (11%)

Query: 44   ELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHS-PIK 102
            ++S+ +  +PP+P + G   K   + +P    +++ P  +  PE SK K   P+ S P+K
Sbjct: 1297 QVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVK 1356

Query: 103  EEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSTHPK 149
            ++P           + + +  P   + +  T   LST   G S+  K
Sbjct: 1357 QKP-----------KEKEKPPPVNKQENAGTLNILSTLSNGNSSKQK 1392



 Score = 32.3 bits (72), Expect = 0.65
 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 12/123 (9%)

Query: 69   KSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPR 128
            K+   S+++ TP  +  P   K  ++ P   P+ EE     + +    E +   TP   +
Sbjct: 1235 KNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPV-EEKSEEGNVSAPGPESKQATTPASRK 1293

Query: 129  SSVD-TPPRLSTPQKGPSTHPKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRESS 187
            SS   + P L  P + P+T P  K       ++P  + +E    +  QPPP      +S 
Sbjct: 1294 SSKQVSQPALVIPPQPPTTGPPRK-------EVPKTTPSEP---KKKQPPPPESGPEQSK 1343

Query: 188  PKK 190
             KK
Sbjct: 1344 QKK 1346


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 35.0 bits (79), Expect = 0.10
 Identities = 53/232 (22%), Positives = 86/232 (37%), Gaps = 32/232 (13%)

Query: 8    VKKDNEKERHKLFQGYETEEREETELSEKIKLE-----CQP-ELSETSQTLPPKP--FSC 59
            + K+  + +H  F   E E+   +E+S+  K +     C P E +ETS T  P    FS 
Sbjct: 2999 MSKETVETQH--FNSIEDEKVTYSEISKVSKHQSYVGLCPPLEETETSPTKSPDSLEFSP 3056

Query: 60   GRSGK-----------GHKRKSPFGSTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGS 108
            G+              G ++ +P   TE    +K L    S V+        I++     
Sbjct: 3057 GKESPSSDVFDHSPIDGLEKLAPLAQTEGGKEIKTLPVYVSFVQVGKQYEKEIQQGGVKK 3116

Query: 109  LSETVCKR---------ELRSQETPEKPRSSV--DTPPRLSTPQKGPSTHPKEKAFSSEI 157
            +    CK            R Q+ P  P+ S   DT  ++S       +    +  SSE 
Sbjct: 3117 IISQECKTVQETRGTFYTTRQQKQPPSPQGSPEDDTLEQVSFLDSSGKSPLTPETPSSEE 3176

Query: 158  EDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVARCLMPSSVAGETSV 209
                + S T   L  +    PSP+P      ++EE      +  +   ET+V
Sbjct: 3177 VSYEFTSKTPDSLIAYIPGKPSPIPEVSEESEEEEQAKSTSLKQTTVEETAV 3228


>gi|7706589 GNAS complex locus NESP55 [Homo sapiens]
          Length = 245

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 32/130 (24%), Positives = 49/130 (37%), Gaps = 26/130 (20%)

Query: 23  YETEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVK 82
           YETE   E+E+  +   E +P   ET+ T  P+       G    + S FG        +
Sbjct: 109 YETESETESEIESETDFETEP---ETAPTTEPETEPEDDRGPVVPKHSTFG--------Q 157

Query: 83  KLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQ- 141
            L      +K ++P  SP +  P              S + P+ PR   +  P    P+ 
Sbjct: 158 SLTQRLHALKLRSPDASPSRAPP--------------STQEPQSPREGEELKPEDKDPRD 203

Query: 142 KGPSTHPKEK 151
              S  PKE+
Sbjct: 204 PEESKEPKEE 213


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,849,756
Number of Sequences: 37866
Number of extensions: 931199
Number of successful extensions: 5536
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 285
Number of HSP's that attempted gapping in prelim test: 5050
Number of HSP's gapped (non-prelim): 666
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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