Guide to the Human Genome
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Search of human proteins with 149193331

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149193331 tripartite motif protein 15 [Homo sapiens]
         (465 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149193331 tripartite motif protein 15 [Homo sapiens]               946   0.0  
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...   387   e-107
gi|4508005 tripartite motif-containing 26 [Homo sapiens]              281   9e-76
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...   278   6e-75
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    255   7e-68
gi|5730009 ret finger protein [Homo sapiens]                          249   3e-66
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   249   5e-66
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   234   1e-61
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              222   6e-58
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             207   1e-53
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            205   8e-53
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            205   8e-53
gi|15208660 tripartite motif protein 21 [Homo sapiens]                204   1e-52
gi|4557743 Mediterranean fever protein [Homo sapiens]                 201   9e-52
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]   199   4e-51
gi|37622899 ring finger protein 137 [Homo sapiens]                    195   8e-50
gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]    185   7e-47
gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]    182   6e-46
gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]    182   6e-46
gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]    182   6e-46
gi|22749269 ring finger protein 129 [Homo sapiens]                    173   3e-43
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    172   4e-43
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    172   4e-43
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   161   1e-39
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    161   1e-39
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]   161   1e-39
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   157   2e-38
gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens]   154   1e-37
gi|217035095 tripartite motif-containing 62 [Homo sapiens]            152   8e-37
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]   151   1e-36

>gi|149193331 tripartite motif protein 15 [Homo sapiens]
          Length = 465

 Score =  946 bits (2445), Expect = 0.0
 Identities = 465/465 (100%), Positives = 465/465 (100%)

Query: 1   MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLC 60
           MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLC
Sbjct: 1   MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLC 60

Query: 61  QEEEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLD 120
           QEEEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLD
Sbjct: 61  QEEEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLD 120

Query: 121 EAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQEL 180
           EAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQEL
Sbjct: 121 EAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQEL 180

Query: 181 EQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRV 240
           EQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRV
Sbjct: 181 EQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRV 240

Query: 241 NQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDP 300
           NQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDP
Sbjct: 241 NQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDP 300

Query: 301 QTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDG 360
           QTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDG
Sbjct: 301 QTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDG 360

Query: 361 GGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRGVRVALD 420
           GGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRGVRVALD
Sbjct: 361 GGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRGVRVALD 420

Query: 421 YEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCLTLKG 465
           YEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCLTLKG
Sbjct: 421 YEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCLTLKG 465


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score =  387 bits (994), Expect = e-107
 Identities = 203/464 (43%), Positives = 284/464 (61%), Gaps = 16/464 (3%)

Query: 16  CTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEE------------ 63
           C +C G L + VTI CGH FCR CL    ++      +   CPLC+E             
Sbjct: 16  CPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSFRPNWQL 75

Query: 64  ----EQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFL 119
               E  E       LG   E  C+EHGEKIYFFCE+D   LCV CRE   H  HT+ FL
Sbjct: 76  ANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHATHTMRFL 135

Query: 120 DEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQE 179
           ++A  PYR+++   L+ L  ER+EI++++ +E++++QVLLTQ+ +K+ QV + F  L++ 
Sbjct: 136 EDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVISEFAHLRKF 195

Query: 180 LEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVR 239
           LE+Q+ +LLA+L   +  I ++RDE+   V+ E+ R  A ++ELEEK ++PA ELL D+R
Sbjct: 196 LEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNERPARELLTDIR 255

Query: 240 VNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLD 299
               RCE +    P A+SP+L ++IRDF ++ L L   M+MF E L   L+ +   I+LD
Sbjct: 256 STLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFELDYEPAHISLD 315

Query: 300 PQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGD 359
           PQT+   L+LSED +  +++ + ++ PD+P RFD    VL   G + GRH W V + L  
Sbjct: 316 PQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGITGGRHTWVVSIDLAH 375

Query: 360 GGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRGVRVAL 419
           GG CTVGV  E V+RKGE+ L  E+GVWAV ++     A  S  T L L E PR VRV+L
Sbjct: 376 GGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFPTRLTLKEQPRQVRVSL 435

Query: 420 DYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCLTL 463
           DYE G VT  NA T+EPI+TFTASF+ KV PFF +W +GS  +L
Sbjct: 436 DYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSSFSL 479


>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
          Length = 539

 Score =  281 bits (719), Expect = 9e-76
 Identities = 178/542 (32%), Positives = 272/542 (50%), Gaps = 82/542 (15%)

Query: 1   MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLC 60
           M  +  L+ + E   C++C   L D VTI CGH FCR C   +  +    SG   +CPLC
Sbjct: 1   MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPI----SGSRPVCPLC 56

Query: 61  QEEEQAETPMAPVPLGPLGETY-----------------------CEEHGEKIYFFCEND 97
           ++  + E       L  L E                         CE H EK++++CE+D
Sbjct: 57  KKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD 116

Query: 98  AEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQV 157
            + LCV CRE   H+ HT   +++A QP+R+++ + L  L  +RD+I+  + + +  +  
Sbjct: 117 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA 176

Query: 158 LLTQIESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLG 217
            L +++ ++  +   FE+  Q L ++   LL +L +LEQ++ + R+++ ++   E+ RL 
Sbjct: 177 ALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLA 236

Query: 218 AQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEM 277
             + ELE K QQPA+EL+QD R   +R   K F   + I+  + KK  +F  K+L+L   
Sbjct: 237 LVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRG 296

Query: 278 MRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPA 337
           +R F   L   LE  +  +TLDPQ+AS  L LSED K V YT   KS    P +FD  P 
Sbjct: 297 LREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPG 356

Query: 338 VLGFPGFSSGRHRWQVDLQ---------------------------LGDG---------- 360
           VLG  GF+ G+  W+V+++                            GDG          
Sbjct: 357 VLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDE 416

Query: 361 ------------------GGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSP 402
                               C VGVA + V+RKG++ L  EDGVWA+ +S    WA+TSP
Sbjct: 417 ESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTSP 476

Query: 403 GTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCLT 462
             +L  +  PR V +ALDYE G VT  NA++QE I+TFTA+F+ ++ PF  +   G+ L 
Sbjct: 477 EAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTRLL 536

Query: 463 LK 464
           L+
Sbjct: 537 LR 538


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score =  278 bits (712), Expect = 6e-75
 Identities = 146/365 (40%), Positives = 216/365 (59%), Gaps = 17/365 (4%)

Query: 16  CTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEE------------ 63
           C +C G L + VTI CGH FCR CL    ++      +   CPLC+E             
Sbjct: 16  CPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSFRPNWQL 75

Query: 64  ----EQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFL 119
               E  E       LG   E  C+EHGEKIYFFCE+D   LCV CRE   H  HT+ FL
Sbjct: 76  ANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHATHTMRFL 135

Query: 120 DEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQE 179
           ++A  PYR+++   L+ L  ER+EI++++ +E++++QVLLTQ+ +K+ QV + F  L++ 
Sbjct: 136 EDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVISEFAHLRKF 195

Query: 180 LEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVR 239
           LE+Q+ +LLA+L   +  I ++RDE+   V+ E+ R  A ++ELEEK ++PA ELL D+R
Sbjct: 196 LEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNERPARELLTDIR 255

Query: 240 VNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLD 299
               RCE +    P A+SP+L ++IRDF ++ L L   M+MF E L   L+ +   I+LD
Sbjct: 256 STLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFELDYEPAHISLD 315

Query: 300 PQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQL-G 358
           PQT+   L+LSED +  +++ + ++ PD+P RFD    VL   G + GRH W    ++ G
Sbjct: 316 PQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGITGGRHTWVWMARVPG 375

Query: 359 DGGGC 363
           D G C
Sbjct: 376 DSGCC 380


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  255 bits (651), Expect = 7e-68
 Identities = 159/484 (32%), Positives = 249/484 (51%), Gaps = 39/484 (8%)

Query: 16  CTLCAGPLEDAVTIPCGHTFCRLCL------PALSQMGAQSSGKI--LLCPLCQE----- 62
           C++C     + V++ CGH+FCR C+      P    +GA +      L CP C+E     
Sbjct: 29  CSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREPARPS 88

Query: 63  EEQAETPMAPV---------PLGPLGE------------TYCEEHGEKIYFFCENDAEFL 101
           + +    +A V         P    GE              C +HGE    +C++D   +
Sbjct: 89  QLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQDDGRAI 148

Query: 102 CVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQ 161
           CV C     H+ H V  LDEA+Q  ++ L SRL  L  E ++ E  +  E ++ + LL Q
Sbjct: 149 CVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKESKELLKQ 208

Query: 162 IESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVK 221
           + +++ +V   F+ L+  L +Q   LL RL EL +++ ++++E + ++  E+T+L     
Sbjct: 209 MAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSS 268

Query: 222 ELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMF 281
           +++E  Q+P  + LQ+ +   SRC       P  +S ++  K+ +   K   L  M++ F
Sbjct: 269 QIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKF 328

Query: 282 SENLAHHLEIDSGV-ITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLG 340
            E+L   LE +  V +TLDP TA+  L+LS D K VR   + + LP+ P RFD    VL 
Sbjct: 329 KEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA 388

Query: 341 FPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWAST 400
             GFSSGRH W+V  ++G   G   GVA E VRRKG    + E+GVWA+ ++  Q WA T
Sbjct: 389 SCGFSSGRHHWEV--EVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVT 446

Query: 401 SP-GTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGS 459
           SP  + L    + R VRVALD E G V+ +  +    ++TF  +F  +VFP F+V   G+
Sbjct: 447 SPERSPLSCGHLSR-VRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGT 505

Query: 460 CLTL 463
            L +
Sbjct: 506 YLRI 509


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  249 bits (637), Expect = 3e-66
 Identities = 159/471 (33%), Positives = 253/471 (53%), Gaps = 34/471 (7%)

Query: 16  CTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQE-----EEQAETPM 70
           C +C     + + + CGH  C  CL      G   +   + CP C+E       +    +
Sbjct: 16  CPVCLQYFAEPMMLDCGHNICCACLARC--WGTAETN--VSCPQCRETFPQRHMRPNRHL 71

Query: 71  APV-----------PLGPLGET-YCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGF 118
           A V           P GP GE   CE+H E +  +CE D   +CV C     H+ H+V  
Sbjct: 72  ANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLP 131

Query: 119 LDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQ 178
           L+EA++ ++++++++L+ L   +D  +  + Q +Q    LL+  + ++ ++   FE+L  
Sbjct: 132 LEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYH 191

Query: 179 ELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDV 238
            L++    LLARL EL+  I+   +  IT+ S  ++ L + + +LEEK QQP  ELLQD+
Sbjct: 192 SLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDI 251

Query: 239 RVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLE-------- 290
               SR E      P    PDL +KI  F +K L L E ++ F+E +   +E        
Sbjct: 252 GDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREA 311

Query: 291 -IDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRH 349
            + S  +TLDP TA  SL+LS++ + VRY+  ++ LPD+P RF+  P VLG P F +GRH
Sbjct: 312 QLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRH 371

Query: 350 RWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISH-QQCWASTSPGTDLPL 408
            W+V  ++GD    T+GV  + V RKG +  + ++G WAV + + ++ WA TSP T LPL
Sbjct: 372 YWEV--EVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPL 429

Query: 409 SEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFT-ASFSGKVFPFFAVWKKG 458
               + V + LDY+AG+V+ +N   +   FTF+ A+F G V P+F++   G
Sbjct: 430 RTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSG 480


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  249 bits (635), Expect = 5e-66
 Identities = 150/455 (32%), Positives = 241/455 (52%), Gaps = 34/455 (7%)

Query: 15  ACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEEEQAETPMAPVP 74
           +C++C   L++ V I CGH FC+ C+    +       +   CP+C++  +  +      
Sbjct: 28  SCSVCLEYLKEPVIIECGHNFCKACITRWWE----DLERDFPCPVCRKTSRYRSLRPNRQ 83

Query: 75  LGPL---------------GETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFL 119
           LG +                E+ C +H E +  FC  D E +C+ C    TH+AHTV  L
Sbjct: 84  LGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVPL 143

Query: 120 DEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQE 179
           D+A Q Y+++L+  LE L  +  EI   K  E++K   L   +ES++ Q+   FE L + 
Sbjct: 144 DDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRR 203

Query: 180 LEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVR 239
           L++++ +LL+RL E EQ I +   E    + ++   L     E+E KC Q   E+L+DV+
Sbjct: 204 LDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVK 263

Query: 240 VNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLD 299
               +CE    +   ++S +L K   +F R+   L ++++    +           +TLD
Sbjct: 264 STLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIAD-----------VTLD 312

Query: 300 PQTASRSLVLSEDRKSVRYTRQK-KSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLG 358
           P+TA  +LVLSEDRKSV++   + + LPD+P RF   P VL   GF+SGRH W+V  ++G
Sbjct: 313 PETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEV--EVG 370

Query: 359 DGGGCTVGVAGEGVRRKGEMGLSAEDGVWAV-IISHQQCWASTSPGTDLPLSEIPRGVRV 417
           D     VGV  + V RKGE+    E G W V + +  +  A+T+P T L +   P+ V +
Sbjct: 371 DKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGI 430

Query: 418 ALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFF 452
            LDYEAG ++ +N   +  I+TFT +F+ K++P F
Sbjct: 431 FLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLF 465


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  234 bits (598), Expect = 1e-61
 Identities = 151/485 (31%), Positives = 242/485 (49%), Gaps = 64/485 (13%)

Query: 15  ACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEEEQAETPMAPVP 74
           +C++C   L++ V I CGH FC+ C+    +       +   CP+C++  +  +      
Sbjct: 28  SCSVCLEYLKEPVIIECGHNFCKACITRWWE----DLERDFPCPVCRKTSRYRSLRPNRQ 83

Query: 75  LGPL---------------GETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFL 119
           LG +                E+ C +H E +  FC  D E +C+ C    TH+AHTV  L
Sbjct: 84  LGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVPL 143

Query: 120 DEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQE 179
           D+A Q Y+++L+  LE L  +  EI   K  E++K   L   +ES++ Q+   FE L + 
Sbjct: 144 DDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRR 203

Query: 180 LEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVR 239
           L++++ +LL+RL E EQ I +   E    + ++   L     E+E KC Q   E+L+DV+
Sbjct: 204 LDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVK 263

Query: 240 VNQ------------------------------SRCEMKTFVSPEAISPDLVKKIRDFHR 269
                                            +RCE    +   ++S +L K   +F R
Sbjct: 264 STLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKNFSNFPR 323

Query: 270 KILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQK-KSLPDS 328
           +   L ++++    +           +TLDP+TA  +LVLSEDRKSV++   + + LPD+
Sbjct: 324 QYFALRKILKQLIAD-----------VTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDT 372

Query: 329 PLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWA 388
           P RF   P VL   GF+SGRH W+V++  GD     VGV  + V RKGE+    E G W 
Sbjct: 373 PRRFTFYPCVLATEGFTSGRHYWEVEV--GDKTHWAVGVCRDSVSRKGELTPLPETGYWR 430

Query: 389 VIISHQQCWASTS-PGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGK 447
           V + +   +A+T+ P T L +   P+ V + LDYEAG ++ +N   +  I+TFT +F+ K
Sbjct: 431 VRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEK 490

Query: 448 VFPFF 452
           ++P F
Sbjct: 491 LWPLF 495


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  222 bits (565), Expect = 6e-58
 Identities = 145/468 (30%), Positives = 235/468 (50%), Gaps = 26/468 (5%)

Query: 1   MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSS--GKILLCP 58
           M +T S K + E   C++C   + + V+I CGH++C LC+    +  +Q     +   CP
Sbjct: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60

Query: 59  LCQEEEQAETPMAPVPLGPLGETY--------CEEHGEKIYFFCENDAEFLCVFCREGPT 110
            C+     ++      LG L E          CEEHGE+ + FCE++ + +C  C   P 
Sbjct: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMSCEEHGEQFHLFCEDEGQLICWRCERAPQ 120

Query: 111 HQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVE 170
           H+ HT   +++  Q Y+++L+  +  L    D   + K     ++     +++ ++ ++ 
Sbjct: 121 HKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIR 180

Query: 171 TAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQP 230
           + F+ LQ  L ++    L RL + EQQ      +Y   +  +   L + + ELEEKCQ  
Sbjct: 181 SDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGS 240

Query: 231 ASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLE 290
           A +LLQ+V    SR       + EA+S +L   + +  +    + +M+R      +H + 
Sbjct: 241 AQKLLQNVNDTLSRSWAVKLETSEAVSLEL-HTMCNVSKLYFDVKKMLR------SHQVS 293

Query: 291 IDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHR 350
                +TLDP TA   L+LSEDR+ V     +++   S  RF   P VLG  GF+SGR  
Sbjct: 294 -----VTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRY 348

Query: 351 WQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCW-ASTSPGTDLPLS 409
           ++VD  +G+G G  +GV  E V+R   M    + G W + +  ++ + A TSP T L L 
Sbjct: 349 FEVD--VGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLH 406

Query: 410 EIPRGVRVALDYEAGQVTLHNAQTQEPIFTF-TASFSGKVFPFFAVWK 456
           E P  V + LDYEAG V+ +N  T   IFTF  ASFS  + P+F V++
Sbjct: 407 EQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQ 454


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  207 bits (528), Expect = 1e-53
 Identities = 148/466 (31%), Positives = 218/466 (46%), Gaps = 39/466 (8%)

Query: 3   ATPSLKV-VHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQ 61
           A P L   + E   C +C     D V   CGH FCR C+    +   Q  G    CP C+
Sbjct: 2   AAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECI---RRCWGQPEGPYA-CPECR 57

Query: 62  E-------------EEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREG 108
           E              + AE      P  P+ +  C  H E +  FC ++   LC  C   
Sbjct: 58  ELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERS 117

Query: 109 PTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQ 168
             H AH V  L +A +  + +L   LE L  +  +    + Q D+   +    +ES++  
Sbjct: 118 GEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQN 177

Query: 169 VETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQ 228
           V   FERL++ L ++   LL RL E E ++     E    + ++   L   + ELE +CQ
Sbjct: 178 VLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQ 237

Query: 229 QPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHH 288
            PA  LLQD++    R +      PE +  +L    R     +  L E +R F       
Sbjct: 238 LPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCR-----VPGLVETLRRF------- 285

Query: 289 LEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGR 348
                G +TLDP TA+  L+LSEDR+SV+    +++LPDSP RFD  P VLG   F+SGR
Sbjct: 286 ----RGDVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGR 341

Query: 349 HRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPL 408
           H W+V  ++GD     +GV  E V RK +  LSA +G W ++      + ++S     PL
Sbjct: 342 HYWEV--EVGDRTSWALGVCRENVNRKEKGELSAGNGFWILVFLGS--YYNSSERALAPL 397

Query: 409 SEIPRGVRVALDYEAGQVTLHNAQTQEPIFTF-TASFSGKVFPFFA 453
            + PR V + LDYEAG ++ ++A     +F F    FSG + P F+
Sbjct: 398 RDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFS 443


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  205 bits (521), Expect = 8e-53
 Identities = 131/457 (28%), Positives = 221/457 (48%), Gaps = 38/457 (8%)

Query: 16  CTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEEEQAETPMAPVPL 75
           C++C   L D VTI CGH FCR C+    Q       ++  CP+C+ + Q     +   L
Sbjct: 16  CSICLDYLSDPVTIECGHNFCRSCI----QQSWLDLQELFPCPVCRHQCQEGHFRSNTQL 71

Query: 76  GPLGE------------------TYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVG 117
           G + E                  T CE+H + +  FC+ D   LC  C + P HQ H V 
Sbjct: 72  GRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQPPDHQGHHVR 131

Query: 118 FLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQ 177
            +++A   YR R  S ++ L  +  +++ +   + +K   L   +E+++ ++ + FE L 
Sbjct: 132 PIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQELSSEFEHLN 191

Query: 178 QELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQD 237
           Q L++++  +L+RL E E+   ++    IT  S     L +Q+ ++ E  +    ELL  
Sbjct: 192 QFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSELSELELLSQ 251

Query: 238 VRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVIT 297
           +++     E +   SP   S  L +    F  +   L  +++ F              I 
Sbjct: 252 IKIFY---ESENESSPSIFSIHLKRDGCSFPPQYSALQRIIKKFKVE-----------II 297

Query: 298 LDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQL 357
           LDP+TA  +L++SED+K VR+T++K+ +P  P RF   P VLGFP F SGRH W++  ++
Sbjct: 298 LDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEI--EV 355

Query: 358 GDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRGVRV 417
           GD     +G+  + +  K     SA+   W + +      A  +  T L L    R + +
Sbjct: 356 GDKSEWAIGICKDSLPTKARRPSSAQQECWRIELQDDGYHAPGAFPTPLLLEVKARAIGI 415

Query: 418 ALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAV 454
            LDYE G+++ +N   +  I TFT +F+G + P+F V
Sbjct: 416 FLDYEMGEISFYNMAEKSHICTFTDTFTGPLRPYFYV 452


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  205 bits (521), Expect = 8e-53
 Identities = 144/471 (30%), Positives = 226/471 (47%), Gaps = 38/471 (8%)

Query: 1   MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLC 60
           M   P  + + E   C +C   L++ V++ CGH+FC  C+    +    + G +  CP C
Sbjct: 1   MAWAPPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQC 60

Query: 61  QEEEQAETPMAPVPLGPLGETY-------------CEEHGEKIYFFCENDAEFLCVFCRE 107
           +   +         L  L E+              C  HGE +  FCE D   LC  C  
Sbjct: 61  RGPFRPSGFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDA 120

Query: 108 GPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQE---DQKLQVLLTQIES 164
           GP H+ H    L EA   Y+ +L+  LE +   R E+ED   QE    +K  +   ++E 
Sbjct: 121 GPEHRTHRTAPLQEAAGSYQVKLQMALELM---RKELEDALTQEANVGKKTVIWKEKVEM 177

Query: 165 KKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELE 224
           ++ +    FE+ +  L Q+    L RL   E+   +   E  +++ ++   L     EL+
Sbjct: 178 QRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQ 237

Query: 225 EKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSEN 284
           E+CQ+PA  LL+ VR   SR +  T +  E I  +L        R+     E++R F   
Sbjct: 238 ERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRR-----ELLRKF--- 289

Query: 285 LAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGF 344
                ++D   + LDP TA  SL+L+ D +SV+     + +P++P RFD  P +LG   F
Sbjct: 290 -----QVD---VKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSF 341

Query: 345 SSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAV-IISHQQCWASTSPG 403
           SSGRH W+V   +G+G    +GV  + + RKGE   S E+GVWA+ ++   +     SP 
Sbjct: 342 SSGRHYWEV--LVGEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPS 399

Query: 404 TDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAV 454
             L   E PR + + LDYEAG+++ +N      I+TF   FSG + P+F +
Sbjct: 400 VPLLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFI 450


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  204 bits (519), Expect = 1e-52
 Identities = 144/479 (30%), Positives = 235/479 (49%), Gaps = 58/479 (12%)

Query: 1   MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLC 60
           M +   L ++ E   C +C  P  + V+I CGH+FC+ C+  + + G        +CP+C
Sbjct: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGS------VCPVC 54

Query: 61  QEEEQAETPMAPVPL----------------GPLGETYCEEHGEKIYFFCENDAEFLCVF 104
           ++    +       L                G  GE  C  HGE+++ FCE D + LC  
Sbjct: 55  RQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGER-CAVHGERLHLFCEKDGKALCWV 113

Query: 105 CREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIES 164
           C +   H+ H +  L+EA Q Y+++L+  L  L  +++  E +      ++++ + + + 
Sbjct: 114 CAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKL------EVEIAIKRADW 167

Query: 165 KKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQ----- 219
           KK  VET   R+  E  QQ+  L+   +   Q++ K+  E +  + E+  +L  Q     
Sbjct: 168 KK-TVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQ 226

Query: 220 --VKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEM 277
             + EL+ +C   A ELLQ+V +   R E       +  SP+L        R +  +P +
Sbjct: 227 ELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPEL--------RSVCHVPGL 278

Query: 278 MRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPA 337
            +M      H        ITLDP TA+  L+LSEDR+ VR    ++S+P +  RFD  P 
Sbjct: 279 KKMLRTCAVH--------ITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPM 330

Query: 338 VLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCW 397
           VLG   F SG+H W+VD+   +     +GV  + VRRKG   LS++ G W + + ++Q +
Sbjct: 331 VLGAQHFHSGKHYWEVDVTGKE--AWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKY 388

Query: 398 -ASTSPGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQ-EPIFTFT-ASFSGKVFPFFA 453
            A T P T L L   P  V + LDYEAG V+ +N       I++F+  +F+G + PFF+
Sbjct: 389 EAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFS 447


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score =  201 bits (512), Expect = 9e-52
 Identities = 137/425 (32%), Positives = 219/425 (51%), Gaps = 31/425 (7%)

Query: 47  GAQSSGKILLCPLCQEEEQAETP--MAPVPLGPLGETYCEEHGEKIYF-FCENDAEFLCV 103
           G++S G    CP CQ+  + ++P  ++P PL       C+ H +++   FCE+  E +C+
Sbjct: 346 GSRSPG----CPRCQDSHERKSPGSLSPQPL-----PQCKRHLKQVQLLFCEDHDEPICL 396

Query: 104 FCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIE 163
            C     HQ H V  ++E    ++ +++ +LE L   R   E+ +   ++K    L Q E
Sbjct: 397 ICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTE 456

Query: 164 SKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKEL 223
           + K +V+   E++   LEQQ    +A L ++ Q + + R  Y T+VS+++  L A + EL
Sbjct: 457 ALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGEL 516

Query: 224 EEKCQQPASELLQDVRVNQSRCEMKTFVSPE--AISPDLVKKIRDFHRKILTLPEMMRMF 281
           E K  Q   ELLQD+     R   KT   PE      ++ +KI+  H+K   + +  + F
Sbjct: 517 EAKECQSEWELLQDIGDILHRA--KTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYF 574

Query: 282 SENLAHHLEI-----------DSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPL 330
           SE L   +E+            +  + LD +TA  +L+ S+D KSVR   + + LPD P 
Sbjct: 575 SETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQ 634

Query: 331 RFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVI 390
           RFD    VLG P F SGR  W+V  ++GD     +G     + RKG M LS E+G W VI
Sbjct: 635 RFDSCIIVLGSPSFLSGRRYWEV--EVGDKTAWILGACKTSISRKGNMTLSPENGYWVVI 692

Query: 391 -ISHQQCWASTSPGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTF-TASFSGKV 448
            +   +  AS+ P T L + E P+ V + +DY  G ++ +N   +  I+TF + SFSG +
Sbjct: 693 MMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPL 752

Query: 449 FPFFA 453
            P F+
Sbjct: 753 QPIFS 757


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score =  199 bits (506), Expect = 4e-51
 Identities = 134/411 (32%), Positives = 208/411 (50%), Gaps = 39/411 (9%)

Query: 83  CEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERD 142
           C +H E +  FCE D E +CV CRE  +H+ H+V  L+E +Q Y+ +L+  +E L    +
Sbjct: 227 CPKHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLE 286

Query: 143 EIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKER 202
            ++ +K +E++++  L +Q++S+   V + F RL + L +++  L  RLRE+ +      
Sbjct: 287 AVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRA 346

Query: 203 DEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVK 262
               ++++E+  +L   + E +E+ QQ    LLQD++   +RCE      PE  SPD  +
Sbjct: 347 GAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQ 406

Query: 263 KIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQK 322
                H        ++R  S        +D   +TLDP TA  +L+LS DR+ VR   ++
Sbjct: 407 P----HSHDFLTDAIVRKMSRMFCQAARVD---LTLDPDTAHPALMLSPDRRGVRLAERR 459

Query: 323 KSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRK---GEMG 379
           + + D P RF     VLG  GF SGRH W+V++  G   G  VG A E    K   G  G
Sbjct: 460 QEVADHPKRFSADCCVLGAQGFRSGRHYWEVEV--GGRRGWAVGAARESTHHKEKVGPGG 517

Query: 380 LSAEDG-------------------------VWAVIISHQQCWA-STSPGTDLPLSEIPR 413
            S   G                         VW V  + ++  A S++  T L  SE PR
Sbjct: 518 SSVGSGDASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPR 577

Query: 414 GVRVALDYEAGQVTLHNAQTQEPIFTFTASFSG-KVFPFFAVWKKGSCLTL 463
              V LDYEAG++  +NA+T   + TF+A+F G +VFPFF V  KG+ + L
Sbjct: 578 RFGVYLDYEAGRLGFYNAETLAHVHTFSAAFLGERVFPFFRVLSKGTRIKL 628



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 4  TPS-LKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPAL 43
          TP+ ++ + E   C +C     D V+I CGH FCR+C+  L
Sbjct: 7  TPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQL 47


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  195 bits (495), Expect = 8e-50
 Identities = 140/487 (28%), Positives = 229/487 (47%), Gaps = 58/487 (11%)

Query: 1   MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLC 60
           M  T  ++ + E  AC +C   L + ++I CGH+FC  CL  L ++  +S      CPLC
Sbjct: 1   MDPTALVEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLC 60

Query: 61  QEEEQAETPMAPVPLGP---------------------LGETYCEEHGEKIYFFCENDAE 99
           +       P+ P  L P                     L    CE HGEK+  FC+ D  
Sbjct: 61  R------APVQPRNLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVL 114

Query: 100 FLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLL 159
            +C  C + P H+AH+V  +++    Y+  L   LE L  E++E   ++  E ++     
Sbjct: 115 IMCEACSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWK 174

Query: 160 TQIESKKHQVETAFERLQQELEQQR----------CLLLARLRELEQQIWKERDEYITKV 209
            Q+E++K  +   FE+ Q+ LE+++             LA L+    +  ++ +   +++
Sbjct: 175 IQVETRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSEL 234

Query: 210 SEEVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHR 269
            ++   L   + EL+E+ Q+P   +LQD++   +R +  +   PE IS +L    R    
Sbjct: 235 IQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCR---- 290

Query: 270 KILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSP 329
            +L L E+++ ++ +           + LDP TA   L++SEDRK V Y    + LPD+P
Sbjct: 291 -VLGLREILKTYAAD-----------VRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNP 338

Query: 330 LRFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAV 389
            RF     VLG    SSGRH W+V  ++GD     +GV  + V RK  + LS   G W +
Sbjct: 339 ERFYRYNIVLGSQCISSGRHYWEV--EVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWVI 396

Query: 390 -IISHQQCWASTSPGTDLPLSEIPRGVRVALDYEAGQVTLHN-AQTQEPIFTFTA-SFSG 446
            +    +  A T     L L   PR V + +DYEA  ++ +N       IFTF    F G
Sbjct: 397 RLRKGNEYRAGTDEYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPG 456

Query: 447 KVFPFFA 453
           ++ P+F+
Sbjct: 457 RLLPYFS 463


>gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]
          Length = 329

 Score =  185 bits (470), Expect = 7e-47
 Identities = 113/314 (35%), Positives = 176/314 (56%), Gaps = 8/314 (2%)

Query: 155 LQVLLT---QIESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSE 211
           LQ+LL    Q+ +++ +V   F+ L+  L +Q   LL RL EL +++ ++++E + ++  
Sbjct: 17  LQLLLLGQKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGV 76

Query: 212 EVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKI 271
           E+T+L     +++E  Q+P  + LQ+ +   SRC       P  +S ++  K+ +   K 
Sbjct: 77  EITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKT 136

Query: 272 LTLPEMMRMFSENLAHHLEIDSGV-ITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPL 330
             L  M++ F E+L   LE +  V +TLDP TA+  L+LS D K VR   + + LP+ P 
Sbjct: 137 FVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPC 196

Query: 331 RFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVI 390
           RFD    VL   GFSSGRH W+V  ++G   G   GVA E VRRKG    + E+GVWA+ 
Sbjct: 197 RFDTNTRVLASCGFSSGRHHWEV--EVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQ 254

Query: 391 ISHQQCWASTSP-GTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVF 449
           ++  Q WA TSP  + L    + R VRVALD E G V+ +  +    ++TF  +F  +VF
Sbjct: 255 LNGGQYWAVTSPERSPLSCGHLSR-VRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVF 313

Query: 450 PFFAVWKKGSCLTL 463
           P F+V   G+ L +
Sbjct: 314 PLFSVCSTGTYLRI 327


>gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  182 bits (462), Expect = 6e-46
 Identities = 108/302 (35%), Positives = 169/302 (55%), Gaps = 5/302 (1%)

Query: 164 SKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKEL 223
           +++ +V   F+ L+  L +Q   LL RL EL +++ ++++E + ++  E+T+L     ++
Sbjct: 3   AEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQI 62

Query: 224 EEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSE 283
           +E  Q+P  + LQ+ +   SRC       P  +S ++  K+ +   K   L  M++ F E
Sbjct: 63  QETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKE 122

Query: 284 NLAHHLEIDSGV-ITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFP 342
           +L   LE +  V +TLDP TA+  L+LS D K VR   + + LP+ P RFD    VL   
Sbjct: 123 DLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASC 182

Query: 343 GFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSP 402
           GFSSGRH W+V  ++G   G   GVA E VRRKG    + E+GVWA+ ++  Q WA TSP
Sbjct: 183 GFSSGRHHWEV--EVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP 240

Query: 403 -GTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCL 461
             + L    + R VRVALD E G V+ +  +    ++TF  +F  +VFP F+V   G+ L
Sbjct: 241 ERSPLSCGHLSR-VRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYL 299

Query: 462 TL 463
            +
Sbjct: 300 RI 301


>gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  182 bits (462), Expect = 6e-46
 Identities = 108/302 (35%), Positives = 169/302 (55%), Gaps = 5/302 (1%)

Query: 164 SKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKEL 223
           +++ +V   F+ L+  L +Q   LL RL EL +++ ++++E + ++  E+T+L     ++
Sbjct: 3   AEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQI 62

Query: 224 EEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSE 283
           +E  Q+P  + LQ+ +   SRC       P  +S ++  K+ +   K   L  M++ F E
Sbjct: 63  QETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKE 122

Query: 284 NLAHHLEIDSGV-ITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFP 342
           +L   LE +  V +TLDP TA+  L+LS D K VR   + + LP+ P RFD    VL   
Sbjct: 123 DLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASC 182

Query: 343 GFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSP 402
           GFSSGRH W+V  ++G   G   GVA E VRRKG    + E+GVWA+ ++  Q WA TSP
Sbjct: 183 GFSSGRHHWEV--EVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP 240

Query: 403 -GTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCL 461
             + L    + R VRVALD E G V+ +  +    ++TF  +F  +VFP F+V   G+ L
Sbjct: 241 ERSPLSCGHLSR-VRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYL 299

Query: 462 TL 463
            +
Sbjct: 300 RI 301


>gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  182 bits (462), Expect = 6e-46
 Identities = 108/302 (35%), Positives = 169/302 (55%), Gaps = 5/302 (1%)

Query: 164 SKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKEL 223
           +++ +V   F+ L+  L +Q   LL RL EL +++ ++++E + ++  E+T+L     ++
Sbjct: 3   AEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQI 62

Query: 224 EEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSE 283
           +E  Q+P  + LQ+ +   SRC       P  +S ++  K+ +   K   L  M++ F E
Sbjct: 63  QETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKE 122

Query: 284 NLAHHLEIDSGV-ITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFP 342
           +L   LE +  V +TLDP TA+  L+LS D K VR   + + LP+ P RFD    VL   
Sbjct: 123 DLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASC 182

Query: 343 GFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSP 402
           GFSSGRH W+V  ++G   G   GVA E VRRKG    + E+GVWA+ ++  Q WA TSP
Sbjct: 183 GFSSGRHHWEV--EVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAVTSP 240

Query: 403 -GTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCL 461
             + L    + R VRVALD E G V+ +  +    ++TF  +F  +VFP F+V   G+ L
Sbjct: 241 ERSPLSCGHLSR-VRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGTYL 299

Query: 462 TL 463
            +
Sbjct: 300 RI 301


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  173 bits (439), Expect = 3e-43
 Identities = 129/471 (27%), Positives = 221/471 (46%), Gaps = 38/471 (8%)

Query: 1   MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLC 60
           M    +L  + E  +C +C   L+D VTI CGH FCR CL     +  +       CP+C
Sbjct: 1   MEFVTALVNLQEESSCPICLEYLKDPVTINCGHNFCRSCL----SVSWKDLDDTFPCPVC 56

Query: 61  QEEEQAETPMAPVPLGPLGE------------------TYCEEHGEKIYFFCENDAEFLC 102
           +     ++      L  L E                    CE+H + +  FC  D E LC
Sbjct: 57  RFCFPYKSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILC 116

Query: 103 VFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQI 162
             C     HQ H +  + +A   +R+ L   LE L    + +E V   +  K   L  ++
Sbjct: 117 TQCSFSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKV 176

Query: 163 ESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKE 222
           E K+ ++ + FE+++  L+ ++ ++L ++++ E  I  + +E + ++S+ V+ L   ++E
Sbjct: 177 EYKREEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLRE 236

Query: 223 LEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFS 282
           +E K  Q   ELL   +      + +    PE  S  L K       +   L  +++ F 
Sbjct: 237 VEGKSVQSNLELL--TQAKSMHHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRIIKPF- 293

Query: 283 ENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFP 342
                  ++D   + LD  TA   L++SEDRK+VRY R+K+++   P RF   PAVLG  
Sbjct: 294 -------QVD---VILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQ 343

Query: 343 GFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSP 402
            FSSGRH W+V  ++G+     +GV  + + R  +   S   G WA+    +  + ++ P
Sbjct: 344 RFSSGRHYWEV--EVGNKPKWILGVCQDCLLRNWQDQPSVLGGFWAIGRYMKSGYVASGP 401

Query: 403 GTDLPLSEI-PRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFF 452
            T   L  + P  + + LDYE G ++ +N   +  ++TF   F+  V+P+F
Sbjct: 402 KTTQLLPVVKPSKIGIFLDYELGDLSFYNMNDRSILYTFNDCFTEAVWPYF 452


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  172 bits (437), Expect = 4e-43
 Identities = 132/481 (27%), Positives = 215/481 (44%), Gaps = 43/481 (8%)

Query: 4   TPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEE 63
           +P L  + E   C +C   L + ++I CGH+FC+ C+    +           CP+CQ  
Sbjct: 3   SPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTS 62

Query: 64  EQAET------------PMAPVPLGP---LGETYCEEHGEKIYFFCENDAEFLCVFCREG 108
            Q                +  V LGP   L    C +HGEK+  FC+ D + +C  C   
Sbjct: 63  YQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 122

Query: 109 PTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQ 168
             H+ H    ++E  Q Y+++ +  L+ L  E  E E +     +K      Q+E ++ +
Sbjct: 123 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 182

Query: 169 VETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQ 228
           ++T F +L+  L++     L +L + E++  +  +E    +  +   L   + +LE +CQ
Sbjct: 183 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 242

Query: 229 QPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHH 288
               ELLQDV     R E  T   PEA+   L        R +   P++ RM    +   
Sbjct: 243 GSTMELLQDVSDVTERSEFWTLRKPEALPTKL--------RSMFRAPDLKRML--RVCRE 292

Query: 289 L-EIDS--GVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFS 345
           L ++ S    +TL+P TA+ +LVL+++R+ VR+   K S P S L      +VLG   FS
Sbjct: 293 LTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGP-SCLEKHYDCSVLGSQHFS 351

Query: 346 SGRHRWQVDLQ---------LGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQ-- 394
           SG+H W+VD+            +  G T                  + G W + + H   
Sbjct: 352 SGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHE 411

Query: 395 -QCWASTSPGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQE-PIFTFTA-SFSGKVFPF 451
            + +  +SP   L ++  PR V V LDYEAG V+ +N      PI+TF+   F   + P+
Sbjct: 412 YRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPY 471

Query: 452 F 452
           F
Sbjct: 472 F 472


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  172 bits (437), Expect = 4e-43
 Identities = 132/481 (27%), Positives = 215/481 (44%), Gaps = 43/481 (8%)

Query: 4   TPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEE 63
           +P L  + E   C +C   L + ++I CGH+FC+ C+    +           CP+CQ  
Sbjct: 31  SPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTS 90

Query: 64  EQAET------------PMAPVPLGP---LGETYCEEHGEKIYFFCENDAEFLCVFCREG 108
            Q                +  V LGP   L    C +HGEK+  FC+ D + +C  C   
Sbjct: 91  YQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERS 150

Query: 109 PTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQ 168
             H+ H    ++E  Q Y+++ +  L+ L  E  E E +     +K      Q+E ++ +
Sbjct: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210

Query: 169 VETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQ 228
           ++T F +L+  L++     L +L + E++  +  +E    +  +   L   + +LE +CQ
Sbjct: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQ 270

Query: 229 QPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHH 288
               ELLQDV     R E  T   PEA+   L        R +   P++ RM    +   
Sbjct: 271 GSTMELLQDVSDVTERSEFWTLRKPEALPTKL--------RSMFRAPDLKRML--RVCRE 320

Query: 289 L-EIDS--GVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFS 345
           L ++ S    +TL+P TA+ +LVL+++R+ VR+   K S P S L      +VLG   FS
Sbjct: 321 LTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGP-SCLEKHYDCSVLGSQHFS 379

Query: 346 SGRHRWQVDLQ---------LGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQ-- 394
           SG+H W+VD+            +  G T                  + G W + + H   
Sbjct: 380 SGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHE 439

Query: 395 -QCWASTSPGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQE-PIFTFTA-SFSGKVFPF 451
            + +  +SP   L ++  PR V V LDYEAG V+ +N      PI+TF+   F   + P+
Sbjct: 440 YRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPY 499

Query: 452 F 452
           F
Sbjct: 500 F 500


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  161 bits (408), Expect = 1e-39
 Identities = 126/480 (26%), Positives = 211/480 (43%), Gaps = 48/480 (10%)

Query: 1   MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLP-----ALSQMGAQSSGKIL 55
           M A    + + E   C++C     D V   CGH FCR C+      A  + G +      
Sbjct: 1   MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF 60

Query: 56  LCPLCQEEEQAET-----------PMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVF 104
            CP C+E                  MA    G   +  C+EH E +  FC+ D   +CV 
Sbjct: 61  PCPECREMSPQRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVV 120

Query: 105 CREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIES 164
           CRE   H+ H V   +EA+Q Y+ +L   +E L  +     +++ +E+Q L     +++ 
Sbjct: 121 CRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKE 180

Query: 165 KKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELE 224
           ++ ++   FE++   L ++   LL  L   E++      E +  +  +   L   + +LE
Sbjct: 181 RRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLE 240

Query: 225 EKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSEN 284
           E+  Q   ++LQD++   SR    +   PE   P   + +     +I    E++R F E+
Sbjct: 241 ERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQI----EVLRGFLED 296

Query: 285 LAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPL--------RFDGLP 336
                      +  D  +A   L+L E       +RQ++ L  SP         RF   P
Sbjct: 297 -----------VVPDATSAYPYLLLYE-------SRQRRYLGSSPEGSGFCSKDRFVAYP 338

Query: 337 AVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQC 396
             +G   FSSGRH W+V + +       +GV  + V RK  +    E+G W V +S    
Sbjct: 339 CAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTK 398

Query: 397 WAST-SPGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFT-ASFSGKVFPFFAV 454
           + ST S  T + L E P  + + LD+EAG+V+ ++      + T++ A+F G + PFF +
Sbjct: 399 YLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCL 458


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  161 bits (408), Expect = 1e-39
 Identities = 126/480 (26%), Positives = 211/480 (43%), Gaps = 48/480 (10%)

Query: 1   MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLP-----ALSQMGAQSSGKIL 55
           M A    + + E   C++C     D V   CGH FCR C+      A  + G +      
Sbjct: 1   MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF 60

Query: 56  LCPLCQEEEQAET-----------PMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVF 104
            CP C+E                  MA    G   +  C+EH E +  FC+ D   +CV 
Sbjct: 61  PCPECREMSPQRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVV 120

Query: 105 CREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIES 164
           CRE   H+ H V   +EA+Q Y+ +L   +E L  +     +++ +E+Q L     +++ 
Sbjct: 121 CRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKE 180

Query: 165 KKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELE 224
           ++ ++   FE++   L ++   LL  L   E++      E +  +  +   L   + +LE
Sbjct: 181 RRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLE 240

Query: 225 EKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSEN 284
           E+  Q   ++LQD++   SR    +   PE   P   + +     +I    E++R F E+
Sbjct: 241 ERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQI----EVLRGFLED 296

Query: 285 LAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPL--------RFDGLP 336
                      +  D  +A   L+L E       +RQ++ L  SP         RF   P
Sbjct: 297 -----------VVPDATSAYPYLLLYE-------SRQRRYLGSSPEGSGFCSKDRFVAYP 338

Query: 337 AVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQC 396
             +G   FSSGRH W+V + +       +GV  + V RK  +    E+G W V +S    
Sbjct: 339 CAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTK 398

Query: 397 WAST-SPGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFT-ASFSGKVFPFFAV 454
           + ST S  T + L E P  + + LD+EAG+V+ ++      + T++ A+F G + PFF +
Sbjct: 399 YLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCL 458


>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score =  161 bits (407), Expect = 1e-39
 Identities = 133/471 (28%), Positives = 220/471 (46%), Gaps = 40/471 (8%)

Query: 5   PSLKVVHELPA---CTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCP--- 58
           PS  V+ ++     C LC     D + + CGH FC  C+    ++ A+ +     CP   
Sbjct: 27  PSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKET----FCPECK 82

Query: 59  -LCQEEEQAETPMAP-----VPLGPL--GETYCEEHGEKIYFFCENDAEFLCVFCREGPT 110
            LCQ       P+       +   PL  G   C EHGE +  F + D + +C  C++   
Sbjct: 83  MLCQYNNCTFNPVLDKLVEKIKKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCKDARL 142

Query: 111 HQAHTVGFLD--EAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKH- 167
               +  FL   +A+  + + L  +   L T   E++ ++   + + + +    E+K H 
Sbjct: 143 SVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLR---NMQKEAIAAHKENKLHL 199

Query: 168 --QVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEE 225
              V   F +L Q L  +   +L  LRE  + + +E +  ++++ E+       +  ++ 
Sbjct: 200 QQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQA 259

Query: 226 KCQQPAS-ELLQDVRVNQSRCE--MKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFS 282
           K +Q  S + L+D+       E  MK   + E IS  L   +  +   I  +  + R   
Sbjct: 260 KTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKL--NLGQYKGPIQYM--VWREMQ 315

Query: 283 ENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFP 342
           + L   L      +TLDP+TA  +LVLS+ + SV +   KK +PD P RFD   AVLG  
Sbjct: 316 DTLCPGLS----PLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSR 371

Query: 343 GFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQ-QCWASTS 401
           GF+SG+  W+V  ++      TVGV  E + RKG   L+ E G W + + +Q    A   
Sbjct: 372 GFTSGKWYWEV--EVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDL 429

Query: 402 PGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFF 452
           P   L L+     V + LDYE GQ++ +NA+T   I+TF+ +F  K++P+F
Sbjct: 430 PSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYF 480


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  157 bits (397), Expect = 2e-38
 Identities = 134/481 (27%), Positives = 209/481 (43%), Gaps = 67/481 (13%)

Query: 10  VHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEEEQAETP 69
           + E   C +C    +D V+I CGH FCR CL      G    G    CP C+       P
Sbjct: 6   IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPS---AP 58

Query: 70  MAPVP---------------LGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAH 114
            A  P               LGP+    C  H E +  FCE+D   +C+ CRE   HQ H
Sbjct: 59  AALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTH 118

Query: 115 TVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFE 174
            +  +DEA + YR++L      L  +  ++  ++  E +       +I+S++ ++ T F 
Sbjct: 119 AMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFS 178

Query: 175 RLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASEL 234
           +L   L ++  L L RL + E++  K+ +E   K+++ +  L   + E+ EK Q P  EL
Sbjct: 179 KLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLEL 238

Query: 235 LQDVRVNQSRCEMKTF-VSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDS 293
           LQ+ +   +R E++    S EA+    V +I         + EM++ F            
Sbjct: 239 LQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIP-------LMKEMLKRFQV---------- 281

Query: 294 GVITLDPQTASRSLVLSEDRKSVRYTRQKKSLP------------DSPL------RFDGL 335
             + L   TA   LV S++ + V+ T    S P             +P       RF  L
Sbjct: 282 -AVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHL 340

Query: 336 PAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGE---GVRRKGEMGLSAEDGVWAVIIS 392
           P VLG   F+SG+H W+V+ +  D     VGV  E   G+  + +M  S + G+WA+  S
Sbjct: 341 PCVLGKNVFTSGKHYWEVESR--DSLEVAVGVCREDVMGITDRSKM--SPDVGIWAIYWS 396

Query: 393 HQQCWASTS-PGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPF 451
               W     PGT          V V LD   G V+ ++A     + TF+ S   ++ PF
Sbjct: 397 AAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPF 456

Query: 452 F 452
           F
Sbjct: 457 F 457


>gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens]
          Length = 518

 Score =  154 bits (390), Expect = 1e-37
 Identities = 87/270 (32%), Positives = 144/270 (53%), Gaps = 7/270 (2%)

Query: 83  CEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERD 142
           C +H E +  FCE D E +CV CRE  +H+ H+V  L+E +Q Y+ +L+  +E L    +
Sbjct: 227 CPKHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLE 286

Query: 143 EIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKER 202
            ++ +K +E++++  L +Q++S+   V + F RL + L +++  L  RLRE+ +      
Sbjct: 287 AVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRA 346

Query: 203 DEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVK 262
               ++++E+  +L   + E +E+ QQ    LLQD++   +RCE      PE  SPD  +
Sbjct: 347 GAAASRLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQ 406

Query: 263 KIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQK 322
                H        ++R  S        +D   +TLDP TA  +L+LS DR+ VR   ++
Sbjct: 407 P----HSHDFLTDAIVRKMSRMFCQAARVD---LTLDPDTAHPALMLSPDRRGVRLAERR 459

Query: 323 KSLPDSPLRFDGLPAVLGFPGFSSGRHRWQ 352
           + + D P RF     VLG  GF SGRH W+
Sbjct: 460 QEVADHPKRFSADCCVLGAQGFRSGRHYWE 489



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 4  TPS-LKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPAL 43
          TP+ ++ + E   C +C     D V+I CGH FCR+C+  L
Sbjct: 7  TPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQL 47


>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
          Length = 475

 Score =  152 bits (383), Expect = 8e-37
 Identities = 126/466 (27%), Positives = 214/466 (45%), Gaps = 50/466 (10%)

Query: 16  CTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEEEQAETPMAP-VP 74
           C++C    +D V++ C H FCR C+        Q +     CP C+    AE  +AP + 
Sbjct: 11  CSICLSIYQDPVSLGCEHYFCRRCIT--EHWVRQEAQGARDCPECRRTF-AEPALAPSLK 67

Query: 75  LGPLGETY-----------------CEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVG 117
           L  + E Y                 C+ H +K+  FC  D   LC FC E   H+ H V 
Sbjct: 68  LANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALHEQHQVT 126

Query: 118 FLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQ 177
            +D+A    +  L+ +L+AL       +D + +  + LQ+L  Q+   K   ++    + 
Sbjct: 127 GIDDAFDELQRELKDQLQAL-------QDSEREHTEALQLLKRQLAETKSSTKSLRTTIG 179

Query: 178 QELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQD 237
           +  E+   LL  R + + +++  +    +T + ++V R   Q+++++E      +++LQ+
Sbjct: 180 EAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQE-----GAQILQE 234

Query: 238 VRVNQSRCEMKTFVSPEA-ISPDLVKKI-------RDFHRKILTLPEMMRMFSENLAHHL 289
                +  +  TF++  A +S  L  KI        DF     T P    ++ ++L   +
Sbjct: 235 ---RLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIW-KSLFQDI 290

Query: 290 EIDSGVITLDPQTASRSLVLSEDRKSVRY-TRQKKSLPDSPLRFDGLPAVLGFPGFSSGR 348
                 +TLDP TA + L+LS+D   V Y     + L DSP RFD   +VLG   FSSG 
Sbjct: 291 HPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGV 350

Query: 349 HRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVII-SHQQCWASTSPGTDLP 407
           H W+V   + +     +G+A E   RKG + +    G + +++    Q  A T P T L 
Sbjct: 351 HYWEV--VVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLN 408

Query: 408 LSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFA 453
           + +    V V LDY+ G +  +NA     ++TF   F GK+  +F+
Sbjct: 409 VRDKLDKVGVFLDYDQGLLIFYNADDMSWLYTFREKFPGKLCSYFS 454


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score =  151 bits (381), Expect = 1e-36
 Identities = 119/450 (26%), Positives = 200/450 (44%), Gaps = 48/450 (10%)

Query: 31  CGHTFCRLCLP-----ALSQMGAQSSGKILLCPLCQEEEQAET-----------PMAPVP 74
           CGH FCR C+      A  + G +       CP C+E                  MA   
Sbjct: 4   CGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQH 63

Query: 75  LGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRL 134
            G   +  C+EH E +  FC+ D   +CV CRE   H+ H V   +EA+Q Y+ +L   +
Sbjct: 64  PGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDM 123

Query: 135 EALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQELEQQRCLLLARLREL 194
           E L  +     +++ +E+Q L     +++ ++ ++   FE++   L ++   LL  L   
Sbjct: 124 EYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETE 183

Query: 195 EQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPE 254
           E++      E +  +  +   L   + +LEE+  Q   ++LQD++   SR    +   PE
Sbjct: 184 EEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPE 243

Query: 255 AISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRK 314
              P   + +     +I    E++R F E+           +  D  +A   L+L E   
Sbjct: 244 VAPPTRPRTVCRVPGQI----EVLRGFLED-----------VVPDATSAYPYLLLYE--- 285

Query: 315 SVRYTRQKKSLPDSPL--------RFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVG 366
               +RQ++ L  SP         RF   P  +G   FSSGRH W+V + +       +G
Sbjct: 286 ----SRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALG 341

Query: 367 VAGEGVRRKGEMGLSAEDGVWAVIISHQQCWAST-SPGTDLPLSEIPRGVRVALDYEAGQ 425
           V  + V RK  +    E+G W V +S    + ST S  T + L E P  + + LD+EAG+
Sbjct: 342 VCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGE 401

Query: 426 VTLHNAQTQEPIFTFT-ASFSGKVFPFFAV 454
           V+ ++      + T++ A+F G + PFF +
Sbjct: 402 VSFYSVSDGSHLHTYSQATFPGPLQPFFCL 431


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,440,501
Number of Sequences: 37866
Number of extensions: 941632
Number of successful extensions: 6532
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 268
Number of HSP's successfully gapped in prelim test: 594
Number of HSP's that attempted gapping in prelim test: 4420
Number of HSP's gapped (non-prelim): 2034
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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