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Search of human proteins with 148762969
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
(5537 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 1.139e+04 0.0
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 1088 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 221 2e-56
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 212 7e-54
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 185 9e-46
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 177 3e-43
gi|110349719 titin isoform N2-A [Homo sapiens] 175 1e-42
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 170 4e-41
gi|116284392 mucin 2 precursor [Homo sapiens] 165 1e-39
gi|61966919 hypothetical protein LOC442444 [Homo sapiens] 162 1e-38
gi|150170670 piccolo isoform 2 [Homo sapiens] 158 2e-37
gi|150378539 piccolo isoform 1 [Homo sapiens] 158 2e-37
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 150 3e-35
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 146 5e-34
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 146 5e-34
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 146 5e-34
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 146 5e-34
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 144 3e-33
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 142 7e-33
gi|33286444 mastermind-like 2 [Homo sapiens] 142 9e-33
gi|47132519 Ras association and pleckstrin homology domains 1 is... 141 2e-32
gi|110347429 mediator complex subunit 12 [Homo sapiens] 139 6e-32
gi|221139761 zinc finger protein 853 [Homo sapiens] 137 2e-31
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 135 9e-31
gi|210032580 SET domain containing 1B [Homo sapiens] 134 3e-30
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 133 4e-30
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 133 6e-30
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 133 6e-30
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 133 6e-30
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 130 5e-29
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 1.139e+04 bits (29556), Expect = 0.0
Identities = 5537/5537 (100%), Positives = 5537/5537 (100%)
Query: 1 MDSQKLAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVLSSGSPRLQETPQDCSG 60
MDSQKLAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVLSSGSPRLQETPQDCSG
Sbjct: 1 MDSQKLAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVLSSGSPRLQETPQDCSG 60
Query: 61 GPVRRCALCNCGEPSLHGQRELRRFELPFDWPRCPVVSPGGSPGPNEAVLPSEDLSQIGF 120
GPVRRCALCNCGEPSLHGQRELRRFELPFDWPRCPVVSPGGSPGPNEAVLPSEDLSQIGF
Sbjct: 61 GPVRRCALCNCGEPSLHGQRELRRFELPFDWPRCPVVSPGGSPGPNEAVLPSEDLSQIGF 120
Query: 121 PEGLTPAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGA 180
PEGLTPAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGA
Sbjct: 121 PEGLTPAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGA 180
Query: 181 SIPCRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAYLEEARCAVCEGPGELCD 240
SIPCRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAYLEEARCAVCEGPGELCD
Sbjct: 181 SIPCRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAYLEEARCAVCEGPGELCD 240
Query: 241 LFFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHT 300
LFFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHT
Sbjct: 241 LFFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHT 300
Query: 301 FCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENYSLCHRCHKAQGGQTIRS 360
FCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENYSLCHRCHKAQGGQTIRS
Sbjct: 301 FCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENYSLCHRCHKAQGGQTIRS 360
Query: 361 VAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG 420
VAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG
Sbjct: 361 VAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG 420
Query: 421 KAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLP 480
KAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLP
Sbjct: 421 KAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLP 480
Query: 481 EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP 540
EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP
Sbjct: 481 EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP 540
Query: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF 600
EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF
Sbjct: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF 600
Query: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660
PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660
Query: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720
RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL
Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720
Query: 721 EESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLC 780
EESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLC
Sbjct: 721 EESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLC 780
Query: 781 AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840
AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP
Sbjct: 781 AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840
Query: 841 CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL 900
CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL
Sbjct: 841 CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL 900
Query: 901 SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYP 960
SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYP
Sbjct: 901 SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYP 960
Query: 961 FGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPL 1020
FGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPL
Sbjct: 961 FGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPL 1020
Query: 1021 PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSE 1080
PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSE
Sbjct: 1021 PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSE 1080
Query: 1081 PECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQT 1140
PECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQT
Sbjct: 1081 PECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQT 1140
Query: 1141 PGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLI 1200
PGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLI
Sbjct: 1141 PGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLI 1200
Query: 1201 KSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLC 1260
KSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLC
Sbjct: 1201 KSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLC 1260
Query: 1261 TDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHG 1320
TDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHG
Sbjct: 1261 TDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHG 1320
Query: 1321 GRGRGRARLKSTASSIETLVVADIDSSPSKEEEEEDDDTMQNTVVLFSNTDKFVLMQDMC 1380
GRGRGRARLKSTASSIETLVVADIDSSPSKEEEEEDDDTMQNTVVLFSNTDKFVLMQDMC
Sbjct: 1321 GRGRGRARLKSTASSIETLVVADIDSSPSKEEEEEDDDTMQNTVVLFSNTDKFVLMQDMC 1380
Query: 1381 VVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRCVECIVCEVCGQASDPS 1440
VVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRCVECIVCEVCGQASDPS
Sbjct: 1381 VVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRCVECIVCEVCGQASDPS 1440
Query: 1441 RLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQCGAASPGFHCEWQNSYTHCGP 1500
RLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQCGAASPGFHCEWQNSYTHCGP
Sbjct: 1441 RLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQCGAASPGFHCEWQNSYTHCGP 1500
Query: 1501 CASLVTCPICHAPYVEEDLLIQCRHCERWMHAGCESLFTEDDVEQAADEGFDCVSCQPYV 1560
CASLVTCPICHAPYVEEDLLIQCRHCERWMHAGCESLFTEDDVEQAADEGFDCVSCQPYV
Sbjct: 1501 CASLVTCPICHAPYVEEDLLIQCRHCERWMHAGCESLFTEDDVEQAADEGFDCVSCQPYV 1560
Query: 1561 VKPVAPVAPPELVPMKVKEPEPQYFRFEGVWLTETGMALLRNLTMSPLHKRRQRRGRLGL 1620
VKPVAPVAPPELVPMKVKEPEPQYFRFEGVWLTETGMALLRNLTMSPLHKRRQRRGRLGL
Sbjct: 1561 VKPVAPVAPPELVPMKVKEPEPQYFRFEGVWLTETGMALLRNLTMSPLHKRRQRRGRLGL 1620
Query: 1621 PGEAGLEGSEPSDALGPDDKKDGDLDTDELLKGEGGVEHMECEIKLEGPVSPDVEPGKEE 1680
PGEAGLEGSEPSDALGPDDKKDGDLDTDELLKGEGGVEHMECEIKLEGPVSPDVEPGKEE
Sbjct: 1621 PGEAGLEGSEPSDALGPDDKKDGDLDTDELLKGEGGVEHMECEIKLEGPVSPDVEPGKEE 1680
Query: 1681 TEESKKRKRKPYRPGIGGFMVRQRKSHTRTKKGPAAQAEVLSGDGQPDEVIPADLPAEGA 1740
TEESKKRKRKPYRPGIGGFMVRQRKSHTRTKKGPAAQAEVLSGDGQPDEVIPADLPAEGA
Sbjct: 1681 TEESKKRKRKPYRPGIGGFMVRQRKSHTRTKKGPAAQAEVLSGDGQPDEVIPADLPAEGA 1740
Query: 1741 VEQSLAEGDEKKKQQRRGRKKSKLEDMFPAYLQEAFFGKELLDLSRKALFAVGVGRPSFG 1800
VEQSLAEGDEKKKQQRRGRKKSKLEDMFPAYLQEAFFGKELLDLSRKALFAVGVGRPSFG
Sbjct: 1741 VEQSLAEGDEKKKQQRRGRKKSKLEDMFPAYLQEAFFGKELLDLSRKALFAVGVGRPSFG 1800
Query: 1801 LGTPKAKGDGGSERKELPTSQKGDDGPDIADEESRGLEGKADTPGPEDGGVKASPVPSDP 1860
LGTPKAKGDGGSERKELPTSQKGDDGPDIADEESRGLEGKADTPGPEDGGVKASPVPSDP
Sbjct: 1801 LGTPKAKGDGGSERKELPTSQKGDDGPDIADEESRGLEGKADTPGPEDGGVKASPVPSDP 1860
Query: 1861 EKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLGCGTPGLEGSRTP 1920
EKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLGCGTPGLEGSRTP
Sbjct: 1861 EKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLGCGTPGLEGSRTP 1920
Query: 1921 LQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPDSPWTGSGGTT 1980
LQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPDSPWTGSGGTT
Sbjct: 1921 LQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPDSPWTGSGGTT 1980
Query: 1981 PSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSS 2040
PSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSS
Sbjct: 1981 PSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSS 2040
Query: 2041 RCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRP 2100
RCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRP
Sbjct: 2041 RCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRP 2100
Query: 2101 ALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELF 2160
ALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELF
Sbjct: 2101 ALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELF 2160
Query: 2161 LKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGA 2220
LKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGA
Sbjct: 2161 LKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGA 2220
Query: 2221 GQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE 2280
GQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE
Sbjct: 2221 GQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE 2280
Query: 2281 SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEP 2340
SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEP
Sbjct: 2281 SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEP 2340
Query: 2341 QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP 2400
QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP
Sbjct: 2341 QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP 2400
Query: 2401 RSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSR 2460
RSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSR
Sbjct: 2401 RSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSR 2460
Query: 2461 DPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVR 2520
DPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVR
Sbjct: 2461 DPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVR 2520
Query: 2521 SPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNY 2580
SPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNY
Sbjct: 2521 SPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNY 2580
Query: 2581 TVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITS 2640
TVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITS
Sbjct: 2581 TVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITS 2640
Query: 2641 PVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTL 2700
PVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTL
Sbjct: 2641 PVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTL 2700
Query: 2701 RQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPI 2760
RQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPI
Sbjct: 2701 RQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPI 2760
Query: 2761 LGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQ 2820
LGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQ
Sbjct: 2761 LGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQ 2820
Query: 2821 QQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIEL 2880
QQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIEL
Sbjct: 2821 QQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIEL 2880
Query: 2881 RHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAP 2940
RHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAP
Sbjct: 2881 RHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAP 2940
Query: 2941 ELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAH 3000
ELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAH
Sbjct: 2941 ELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAH 3000
Query: 3001 KALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTG 3060
KALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTG
Sbjct: 3001 KALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTG 3060
Query: 3061 DKKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKP 3120
DKKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKP
Sbjct: 3061 DKKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKP 3120
Query: 3121 KVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTA 3180
KVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTA
Sbjct: 3121 KVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTA 3180
Query: 3181 EKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSL 3240
EKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSL
Sbjct: 3181 EKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSL 3240
Query: 3241 VASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHE 3300
VASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHE
Sbjct: 3241 VASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHE 3300
Query: 3301 GSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQ 3360
GSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQ
Sbjct: 3301 GSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQ 3360
Query: 3361 HGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDI 3420
HGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDI
Sbjct: 3361 HGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDI 3420
Query: 3421 IDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQ 3480
IDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQ
Sbjct: 3421 IDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQ 3480
Query: 3481 ERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRK 3540
ERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRK
Sbjct: 3481 ERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRK 3540
Query: 3541 ALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQ 3600
ALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQ
Sbjct: 3541 ALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQ 3600
Query: 3601 QQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPG 3660
QQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPG
Sbjct: 3601 QQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPG 3660
Query: 3661 GMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQ 3720
GMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQ
Sbjct: 3661 GMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQ 3720
Query: 3721 LQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPS 3780
LQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPS
Sbjct: 3721 LQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPS 3780
Query: 3781 SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQL 3840
SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQL
Sbjct: 3781 SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQL 3840
Query: 3841 AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQL 3900
AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQL
Sbjct: 3841 AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQL 3900
Query: 3901 QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ 3960
QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ
Sbjct: 3901 QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ 3960
Query: 3961 QQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLL 4020
QQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLL
Sbjct: 3961 QQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLL 4020
Query: 4021 LTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQP 4080
LTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQP
Sbjct: 4021 LTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQP 4080
Query: 4081 QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVS 4140
QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVS
Sbjct: 4081 QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVS 4140
Query: 4141 LGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQ 4200
LGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQ
Sbjct: 4141 LGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQ 4200
Query: 4201 LQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQ 4260
LQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQ
Sbjct: 4201 LQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQ 4260
Query: 4261 PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRP 4320
PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRP
Sbjct: 4261 PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRP 4320
Query: 4321 SQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
SQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP
Sbjct: 4321 SQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
Query: 4381 DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPI 4440
DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPI
Sbjct: 4381 DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPI 4440
Query: 4441 GAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQ 4500
GAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQ
Sbjct: 4441 GAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQ 4500
Query: 4501 KLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELS 4560
KLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELS
Sbjct: 4501 KLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELS 4560
Query: 4561 LLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPP 4620
LLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPP
Sbjct: 4561 LLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPP 4620
Query: 4621 TPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAAL 4680
TPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAAL
Sbjct: 4621 TPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAAL 4680
Query: 4681 PTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPV 4740
PTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPV
Sbjct: 4681 PTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPV 4740
Query: 4741 IPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVM 4800
IPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVM
Sbjct: 4741 IPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVM 4800
Query: 4801 VAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQF 4860
VAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQF
Sbjct: 4801 VAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQF 4860
Query: 4861 DAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSP 4920
DAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSP
Sbjct: 4861 DAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSP 4920
Query: 4921 LAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLK 4980
LAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLK
Sbjct: 4921 LAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLK 4980
Query: 4981 KWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRPDKVPRDMRRCCFCHEEGD 5040
KWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRPDKVPRDMRRCCFCHEEGD
Sbjct: 4981 KWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRPDKVPRDMRRCCFCHEEGD 5040
Query: 5041 GATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGA 5100
GATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGA
Sbjct: 5041 GATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGA 5100
Query: 5101 TSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPMHKIKGPCEQELSSFAVFRRVYIERD 5160
TSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPMHKIKGPCEQELSSFAVFRRVYIERD
Sbjct: 5101 TSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPMHKIKGPCEQELSSFAVFRRVYIERD 5160
Query: 5161 EVKQIASIIQRGERLHMFRVGGLVFHAIGQLLPHQMADFHSATALYPVGYEATRIYWSLR 5220
EVKQIASIIQRGERLHMFRVGGLVFHAIGQLLPHQMADFHSATALYPVGYEATRIYWSLR
Sbjct: 5161 EVKQIASIIQRGERLHMFRVGGLVFHAIGQLLPHQMADFHSATALYPVGYEATRIYWSLR 5220
Query: 5221 TNNRRCCYRCSIGENNGRPEFVIKVIEQGLEDLVFTDASPQAVWNRIIEPVAAMRKEADM 5280
TNNRRCCYRCSIGENNGRPEFVIKVIEQGLEDLVFTDASPQAVWNRIIEPVAAMRKEADM
Sbjct: 5221 TNNRRCCYRCSIGENNGRPEFVIKVIEQGLEDLVFTDASPQAVWNRIIEPVAAMRKEADM 5280
Query: 5281 LRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYLFRYGRHPLMELPLMINPTGCAR 5340
LRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYLFRYGRHPLMELPLMINPTGCAR
Sbjct: 5281 LRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYLFRYGRHPLMELPLMINPTGCAR 5340
Query: 5341 SEPKILTHYKRPHTLNSTSMSKAYQSTFTGETNTPYSKQFVHSKSSQYRRLRTEWKNNVY 5400
SEPKILTHYKRPHTLNSTSMSKAYQSTFTGETNTPYSKQFVHSKSSQYRRLRTEWKNNVY
Sbjct: 5341 SEPKILTHYKRPHTLNSTSMSKAYQSTFTGETNTPYSKQFVHSKSSQYRRLRTEWKNNVY 5400
Query: 5401 LARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHV 5460
LARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHV
Sbjct: 5401 LARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHV 5460
Query: 5461 IDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQ 5520
IDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQ
Sbjct: 5461 IDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQ 5520
Query: 5521 HKIPCHCGAWNCRKWMN 5537
HKIPCHCGAWNCRKWMN
Sbjct: 5521 HKIPCHCGAWNCRKWMN 5537
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 1088 bits (2813), Expect = 0.0
Identities = 754/2040 (36%), Positives = 1025/2040 (50%), Gaps = 270/2040 (13%)
Query: 3654 GLRLTPGGMALPGQPGGPFLNTALA------QQQQQQHSGGAGSLAGPSGGFFPGNLALR 3707
G+++ PG + PG +N +L Q Q G S++GP P LA +
Sbjct: 2986 GVQVNPGLI-----PGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQ 3040
Query: 3708 SLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQ 3767
+ +ER L L++Q + L L Q++Q+QQQQ+ + + Q+ + P + +
Sbjct: 3041 N--------RERPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIR-QRSEPFFPNIDFDA 3091
Query: 3768 ALGPKPQGLMPP-SSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGA-LGPQGPHR 3825
P + M ++ Q PP QV Q G LGPQ +
Sbjct: 3092 ITDPIMKAKMVALKGINKVMAQNNLGMPPMVMSRFPFMGQVVTGTQNSEGQNLGPQAIPQ 3151
Query: 3826 QVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSG 3885
+T +S P G G + +Q ++ Q QQ +L++ + +H
Sbjct: 3152 DGSITHQ--ISRPNPPNFGPGFVNDS--QRKQYEEWLQETQQLLQMQQKYLEEQIGAHRK 3207
Query: 3886 QPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQ--- 3942
K + + ++ ++ + +QL+ +QQ Q+QL+Q + QQ++ + ++
Sbjct: 3208 SKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRI 3267
Query: 3943 QQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMP 4002
+QQQQ + Q Q ++Q + PQQ Q QQ
Sbjct: 3268 KQQQQCAMAPPTMMPSVQPQPPLIPGATPPT----MSQPTFPMVPQQLQHQQHTTVISGH 3323
Query: 4003 AKPLQHFSSPG----------ALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIG 4052
P++ S PG L P + Q + + T + Q GP
Sbjct: 3324 TSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGP---- 3379
Query: 4053 TTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAG 4112
P + S + ++ Q + Q L + + QQ+ ++
Sbjct: 3380 -PPRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVDRQRALQQRMEME------ 3432
Query: 4113 GGSHGQLGSGSSSEASSVPHL----------LAQPSVSLGDQPGSMTQNLLGPQQ----- 4157
HG +GS SS +SV + QP L P Q QQ
Sbjct: 3433 --QHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQ 3490
Query: 4158 -----PMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLR 4212
P + MQ N Q P V S G +V Q L G + +R
Sbjct: 3491 GSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVR 3550
Query: 4213 HLSPQQQQQLQAL--LMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQ 4270
P L A + L Q T + PG+ S +Q P+ G
Sbjct: 3551 ---PSFTPALPAAPPVANSSLPCGQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRT 3607
Query: 4271 TGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPS---SPQEPKRPSQLPSPS 4327
++ A + P+ P + T P PTP S S PS+LP +
Sbjct: 3608 RKKKRDDDAEST-----KAPSTPHSDITAP------PTPGISETTSTPAVSTPSELPQQA 3656
Query: 4328 SQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQ 4387
Q E P P TP + AA QL L +K P++
Sbjct: 3657 DQESVE----PVGPSTP--------------NMAAGQLCTELENK------LPNSDFSQA 3692
Query: 4388 KPEQSSLVPGHLDQVNGQVVPEASQLSIKQEP------REEPCALGAQSVKREANGE--P 4439
P Q + +D+++ + + ++ +++ +EEP K E N P
Sbjct: 3693 TPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACP 3752
Query: 4440 IGAPGTSNHLLLA-GPRSEAGHLLLQKLLRAKNVQLSTGRGSEG-LRAEINGHIDSKLAG 4497
+ + + H A + ++G+ LL+ LL+ K + EG + +E + D+KL
Sbjct: 3753 VSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVE 3812
Query: 4498 LEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQ 4557
+ +G + + + S+ R K + G +A+ K+ K
Sbjct: 3813 KQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETK-KQRSKRTQRTGEKAAPRSKKRKKD 3871
Query: 4558 ELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLS 4617
E A+ + D ++ L +NNLS
Sbjct: 3872 EEE------------------------------------KQAMYSSTDTFTHLKQQNNLS 3895
Query: 4618 NPPTPPSSLPPTPPPSVQQKMVNGVTPSEE----------------LGEHPKDAASARDS 4661
NPPTPP+SLPPTPPP QKM NG +EE LG P
Sbjct: 3896 NPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQD 3955
Query: 4662 ERALRDTSE-VKSLDLLAALPTPPHNQTEDVRMESD-EDSDSPDSIVPASSPESILGEEA 4719
+ R ++ K++D+ A+LPTPPHN E++R++ D D+PDS VP+SSPES++G E
Sbjct: 3956 DLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEV 4015
Query: 4720 PRFPHLGSGRWEQEDRALSPVIPLIP----RASIPVFPDTKPY-GALGLEVP-GKLPVTT 4773
R+P L + E + SP+IP++P ++S D K G L P G P
Sbjct: 4016 SRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSP--- 4072
Query: 4774 WEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEV-LFPESPA-------- 4824
+ +SV +T+ AA+N++ V+ A ++LL ++IPNSYEV P+ P+
Sbjct: 4073 -NGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHR 4131
Query: 4825 -RAGTE---------PKKGEAEGP---------------GGKEKGLEG---------KSP 4850
G E P G A P GL G +S
Sbjct: 4132 INPGLEYRQHLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESA 4191
Query: 4851 DTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP 4910
P W V+ G ++ L+LL ++S + + +N + S
Sbjct: 4192 ALRPQWCCHCKVVILGSGVRKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCFILYSSTAQ 4251
Query: 4911 PEE-------PSPPPSPLAPSPASP-----------PTEPLVELP--TEPLAEPPVPSPL 4950
+ PS P SP+ +P+ L +LP P A PP+ P
Sbjct: 4252 AKNSENKESIPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKASPPASPPIAFPP 4311
Query: 4951 PLASSPESARP---------KPRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSG 5001
++ A+P KPR R G + P KKW+G++WK+ + + I KG+
Sbjct: 4312 AFEAAQVEAKPDELKVTVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTF 4371
Query: 5002 RQEDEREVAEFMEQLGTALRPDKVPRDMRRCCFCHEEGDGATDGPARLLNLDLDLWVHLN 5061
+ E E+ EF+++LGT+L+PD VP+D R+CCFCHEEGDG TDGPARLLNLDLDLWVHLN
Sbjct: 4372 KPPCEDEIDEFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLN 4431
Query: 5062 CALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRA 5121
CALWSTEVYETQ GAL+NVE+AL RGL KC C +TGATS C+R RC N+YHF CAI+A
Sbjct: 4432 CALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKA 4491
Query: 5122 KCMFFKDKTMLCPMHKIKGPCEQELSSFAVFRRVYIERDEVKQIASIIQRGERLHMFRVG 5181
+CMFFKDKTMLCPMHK KG EQELS FAVFRRVY++RDEV+QIASI+QRGER H FRVG
Sbjct: 4492 QCMFFKDKTMLCPMHKPKGIHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVG 4551
Query: 5182 GLVFHAIGQLLPHQMADFHSATALYPVGYEATRIYWSLRTNNRRCCYRCSIGENNGRPEF 5241
L+FH IGQLLP QM FHS AL+PVGYEA+R+YWS R NRRC Y CSI E +GRP F
Sbjct: 4552 SLIFHTIGQLLPQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVF 4611
Query: 5242 VIKVIEQGLEDLVFTDASPQAVWNRIIEPVAAMRKEADMLRLFPEYLKGEELFGLTVHAV 5301
VI+++EQG EDLV +D SP+ VW++I+EPVA +RK+++ML+LFP YLKGE+LFGLTV AV
Sbjct: 4612 VIRIVEQGHEDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAV 4671
Query: 5302 LRIAESLPGVESCQNYLFRYGRHPLMELPLMINPTGCARSEPKILTHYK----RPHTLNS 5357
RIAESLPGVE+C+NY FRYGR+PLMELPL +NPTGCARSEPK+ H K RPHTLNS
Sbjct: 4672 ARIAESLPGVEACENYTFRYGRNPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNS 4731
Query: 5358 TSMSKAYQSTFTGETNTPYSKQFVHSKSSQYRRLRTEWKNNVYLARSRIQGLGLYAAKDL 5417
TS SK++QST TGE N PYSKQFVHSKSSQYR+++TEWK+NVYLARSRIQGLGLYAA+D+
Sbjct: 4732 TSTSKSFQSTVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDI 4791
Query: 5418 EKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSC 5477
EKHTMVIEYIGTIIRNEVANR+EK+YE QNRG+YMFR++N+HVIDATLTGGPARYINHSC
Sbjct: 4792 EKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSC 4851
Query: 5478 APNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN 5537
APNCVAEVVTF++ KIII SSRRI KGEEL YDY+FDFEDDQHKIPCHCGA NCRKWMN
Sbjct: 4852 APNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN 4911
Score = 1058 bits (2736), Expect = 0.0
Identities = 942/2942 (32%), Positives = 1295/2942 (44%), Gaps = 586/2942 (19%)
Query: 1288 KGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRG-RGRARLKSTASSIETLVVADIDS 1346
K R+ A IK GR S FPG+RRPRG GRG RGR++LKS ++ V+ D
Sbjct: 870 KPRQLPGSAIWSIKVGRGSGFPGKRRPRGAGLSGRGGRGRSKLKSGIGAVVLPGVSTADI 929
Query: 1347 SPSKEEEEEDDDTMQNTVVLFSNTDKFVLMQDMCVVCGSFGRGAEGHLLACSQCSQCYHP 1406
S +K++EE ++M NTVVLFS++DKF L QDMCVVCGSFG+GAEG LLACSQC QCYHP
Sbjct: 930 SSNKDDEE---NSMHNTVVLFSSSDKFTLNQDMCVVCGSFGQGAEGRLLACSQCGQCYHP 986
Query: 1407 YCVNSKITKVMLLKGWRCVECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTVPK 1466
YCV+ KITKV+L KGWRC+EC VCE CG+A+DP RLLLCDDCDISYHTYCLDPPL TVPK
Sbjct: 987 YCVSIKITKVVLSKGWRCLECTVCEACGKATDPGRLLLCDDCDISYHTYCLDPPLQTVPK 1046
Query: 1467 GGWKCKWCVSCMQCGAASPGFHCEWQNSYTHCGPCASLVTCPICHAPYVEEDLLIQCRHC 1526
GGWKCKWCV C CGA S G CEWQN+YT C PCASL +CP+C+ Y EEDL++QCR C
Sbjct: 1047 GGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAPCASLSSCPVCYRNYREEDLILQCRQC 1106
Query: 1527 ERWMHAGCESLFTEDDVEQAADEGFDCVSCQPYVVK---PVAPVAPPELVPM---KVKEP 1580
+RWMHA C++L TE++VE AD GFDC C+PY+ P + LV KVKE
Sbjct: 1107 DRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPASNVPSSDCCESSLVAQIVTKVKEL 1166
Query: 1581 E-PQYFRFEGVWLTETGMALLRNLTMS-PLHKRRQRRGRLGLPGEAGLEGSEPSDALGPD 1638
+ P+ + +GV LTE+GM L++LT++ P KR + + +L + + + + + +
Sbjct: 1167 DPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRSKPKLKLKIINQNSVAVLQTPPDIQSE 1226
Query: 1639 DKKDGDLDTDELLKGEGGVEHMECEIKLEGPVSPDVE------PGKEETEESKKRKRKPY 1692
+DG++D EG E M+C+ K E SP+ E G E T+ KKRKRKPY
Sbjct: 1227 HSRDGEMDDSR----EG--ELMDCDGKSES--SPEREAVDDETKGVEGTDGVKKRKRKPY 1278
Query: 1693 RPGIGGFMVRQRKSHTRTKKGPAAQAEV-LSGDGQPDEVIPA-------DLPAEGAVEQS 1744
RPGIGGFMVRQR +RT +G ++ + G E +P LP + V++S
Sbjct: 1279 RPGIGGFMVRQR---SRTGQGKTKRSVIRKDSSGSISEQLPCRDDGWSEQLP-DTLVDES 1334
Query: 1745 LAEGDEKKKQQRRGRK-KSKLEDMFPAYLQEAFFGKELLDLSRKALFAVG---------V 1794
++ + +K ++R RK K+KLE+ FPAYLQEAFFGK+LLD SR++ ++ +
Sbjct: 1335 VSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSKISLDNLSEDGAQLL 1394
Query: 1795 GRPSFGLGTPKAKGDGGSERKELPTSQKGDDGP--DIADEESRGLEGKADTPGPEDGGVK 1852
+ + G D PT + G GP D + S L D G +
Sbjct: 1395 YKTNMNTGFLDPSLDPLLSSSSAPT-KSGTHGPADDPLADISEVLNTDDDILGIISDDLA 1453
Query: 1853 AS-------PVPSDPEKPGTPG-------------EGMLSSDLDRISTE--------ELP 1884
S PV DP P +G+LS +LD++ T+ ++P
Sbjct: 1454 KSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMVTDGAILGKLYKIP 1513
Query: 1885 KMESKDLQQLFKDVLGSEREQHLGCGTPGLEGSRTPL-------QRPFLQG------GLP 1931
++ KD++ LF VL Q P P+ + P + G LP
Sbjct: 1514 ELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLP 1573
Query: 1932 LGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPDSPWTGSGGTTPSTPTTPTTEG 1991
+LP S + ++ + QS + D+R++ F+P +P++ WT S PT EG
Sbjct: 1574 HNSLPPGSGLGTFSAIAQSSYPDARDKNSAFNPMASDPNNSWTSS---------APTVEG 1624
Query: 1992 EGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSSRCKQIMKLWRK 2051
E D +S QRS +WEK+E LG+++T++PVLY NINFPNLK+++PDW++R KQI KLWRK
Sbjct: 1625 ENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRK 1684
Query: 2052 VPAADKAPYLQKAKDNRAAHRINKVQ------------------------------KQAE 2081
+ ++APY+QKA+DNRAA RINKVQ KQ E
Sbjct: 1685 ASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPLKQRE 1744
Query: 2082 SQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIF--------IGSPTTPA 2133
S+ ++ K R+ + + + + + F GS T +
Sbjct: 1745 SEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSDTPSS 1804
Query: 2134 GLSTSADGFLKPPAGS---VPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFP 2190
G+ + L P G+ P ELF K PP P S D F ++P+ P
Sbjct: 1805 GIQSP----LTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF-------VKPQAP 1853
Query: 2191 TAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTP-DPFLKPRC 2249
PP AP++ P+ + S+ QP PG+ +P +P DP+ K
Sbjct: 1854 PPPP----------APSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAK--- 1900
Query: 2250 PSLDNLAVPESPGVGGG----KASEPLLSPPPFGESRKALEVKKEELGASSP-------- 2297
+ P P VG ++ P+ + P + L++ + SP
Sbjct: 1901 ----MVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSS 1956
Query: 2298 -------------------SYGPPNLGFVDSP--SSGTHLGGLELKTPDVFKAPLTPRAS 2336
P +LG SP S T G + T D F P +PRA
Sbjct: 1957 TTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKP-SPRAD 2015
Query: 2337 QVEPQ------------------SPGLGLRPQEPPP------------AQALAPSPPSHP 2366
+ Q PG P +PPP ++ L+ P P
Sbjct: 2016 VFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERP 2075
Query: 2367 -------DIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQS 2419
D F DPY+QPPLTP P A P R+ P S
Sbjct: 2076 ALTPRPIDNFSHNQSNDPYSQPPLTPH---PAVNESFAHPSRAFSQPGTISRPTS--QDP 2130
Query: 2420 SSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPS--RPQSRDPFAPLHKPPRPQPPEV 2477
SQ P TPRP+ +++ S T R + DPYS+PP RP + DP++ + PRP
Sbjct: 2131 YSQPPGTPRPV-VDSYSQSSGTAR-SNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTD 2188
Query: 2478 AFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFT 2537
F + + P A P G VP QPP TP P
Sbjct: 2189 LF----VTPVTNQRHSDPYAHPPG-TPRPGISVPYSQPP------------ATPRP---R 2228
Query: 2538 FPQAVGEPSLKPPVPQPGLPPPHGINSHFG---PGPTLGKPQSTNYTVATGNFHPSGSPL 2594
+ S+ PV P P + G PGP + P + + T P
Sbjct: 2229 ISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQT---------PRPP 2279
Query: 2595 GPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGS 2654
GP T S R P P P S G SQ + + + G+ S
Sbjct: 2280 GPGLSDTFSRVSPSAARDPYDQSPMTPRSQSD--SFGTSQTAHDVADQPRPGSEGSFCAS 2337
Query: 2655 SLATAELPGTQDPGMS------------------GLSQTELEKQRQRQRLRELLIRQQIQ 2696
S + G Q G+S ++Q + EK RQRQ+LRE++++QQ Q
Sbjct: 2338 SNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQ 2397
Query: 2697 RNTL-RQEKETA-AAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPS 2754
+ RQEK + + A GP W E + AF +R P+ G + P +
Sbjct: 2398 KKIAGRQEKGSQDSPAVPHPGPLQHWQPENVNQAF---TRPPPPYPGN------IRSPVA 2448
Query: 2755 KLSGPILGP--GSFPSDDRLSRPPPPATPSSMDVNSR-QLVGGSQAFYQRAPYPGSLPLQ 2811
P LGP FP D R PP A+ R GGS G++P Q
Sbjct: 2449 ----PPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSH---------GTMPSQ 2495
Query: 2812 QQQQQLWQQQQATAAT-SMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPG 2870
++ QQ Q + + +R ++S P +G P LP + G
Sbjct: 2496 ERFLVPPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILG 2555
Query: 2871 PAGPAQFIELRHNVQKG------LGPGGTPFPGQGPPQRPRFYPVSE-------DPHRLA 2917
A +IELRH G P G+ + F P + DP R
Sbjct: 2556 QA----YIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPRPDFPGPRHTDPMRRP 2611
Query: 2918 PEGLRGLAVSGLP--PQKPSAPPA-PELNNSLHPTPHT-KGPTLPTGLELVNRPPSSTEL 2973
P+GL + LP P PP+ E +S+H + + P G E P S++
Sbjct: 2612 PQGL----PNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVP 2667
Query: 2974 GRPNPLALEAGKLPCE--DPELDDDFDAHKALE------------DDEELAHLGLGVDVA 3019
L+ P + + +LD D + K L+ DDE+L +L L +
Sbjct: 2668 SETTSDNLQITTQPSDGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDG 2727
Query: 3020 KGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEK 3079
K EL TL+NLETNDP+LDDLL EFD++AYTDPELD GDKK +FNE L L ++K
Sbjct: 2728 K-VVELDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDMGDKKSMFNEELDL--PIDDK 2784
Query: 3080 AEREALLRGVEPGPLGPEERPPPAADASEP-RLASVLPEVKPKV---------------- 3122
+ + + VEP E + +D P + ++V EVK +V
Sbjct: 2785 LDNQCV--SVEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKN 2842
Query: 3123 -----------------------EEGGRHP-SPCQFTIATPKVEPAPAANSLGLGLK-PG 3157
E+ HP P F T + P+AN + + P
Sbjct: 2843 DENKDNVDTPCSQASAHSDLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPA 2902
Query: 3158 QSMMGSRDTRMGTGPFSS--SGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFEL 3215
Q ++ S T SS + ++ + +G PP L SP
Sbjct: 2903 QDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTLPASP--------------- 2947
Query: 3216 ESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQ 3275
+ +LP A G LD +S V + + H + Q+ P
Sbjct: 2948 SNHVSSLPPFIAPPGRVLDNAMNSNVT------VVSRVNHVFSQ-------GVQVNPGLI 2994
Query: 3276 QQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPP 3335
Q HSL + Q + + S++G QQ + +PQ L
Sbjct: 2995 PGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSGPQQLM-----------IPQTL------ 3037
Query: 3336 AHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQ 3395
A Q R P + QP+L Q + + Q
Sbjct: 3038 --AQQNRERPLLL-----------------------EEQPLLLQDLLDQERQEQQQQRQM 3072
Query: 3396 LAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQV 3455
AM +Q + FFP+ D D I DPI KAKMVALKGI KVMAQ ++G+ P M +
Sbjct: 3073 QAMIRQRSEPFFPNIDFDA-----ITDPIMKAKMVALKGINKVMAQNNLGMPP-MVMSRF 3126
Query: 3456 SLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLF 3515
+ Q ++G +S+ QN Q+ S RPNPP F G +N++ ++QYEEWL
Sbjct: 3127 PFMGQVVTGTQNSEGQNLGPQAIPQDGSITHQIS-RPNPPNFGPGFVNDSQRKQYEEWLQ 3185
Query: 3516 HTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQ 3575
TQQLLQMQ K LEEQIG HRKS+KAL AKQRTAKKAGREFPE DAE+LK VTEQQS +Q
Sbjct: 3186 ETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQ 3245
Query: 3576 KQLDQVRKQQKEHTNLMAEYRNKQQQQ------------QQQ------------------ 3605
KQL+Q+RKQQKEH L+ +YR KQQQQ Q Q
Sbjct: 3246 KQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQPTFP 3305
Query: 3606 ---QQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGM 3662
QQ Q QQH+ V +S SP + LPG P PP R+ P
Sbjct: 3306 MVPQQLQHQQHTTV--ISGHTSPVRMPSLPGWQPNSAPAHLPLNPP-------RIQPPIA 3356
Query: 3663 ALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQL- 3721
LP + P + G S A P G P + P S QER+
Sbjct: 3357 QLPIKTCTP--------------APGTVSNANPQSG-PPPRVEFDDNNPFSESFQERERK 3401
Query: 3722 -----QLQQQRMQLAQKLQQQ---QQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP 3773
Q ++QR+QL Q++ +Q QQ+ + +QH G V + +T+ + P
Sbjct: 3402 ERLREQQERQRIQLMQEVDRQRALQQRMEMEQH--GMVGSEISSS-----RTSVSQIPFY 3454
Query: 3774 QGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLM--TQ 3831
+P Q L Q SPQ Q +G VLQQQ+ P Q M +
Sbjct: 3455 SSDLPCDFMQPLGPLQQSPQHQQ----QMG----QVLQQQNIQQGSINSPSTQTFMQTNE 3506
Query: 3832 SRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSA 3891
R + P + Q G+++G S QQS + S P L A
Sbjct: 3507 RRQVGPPSFVPDSPS------IPVGSPNFSSVKQGHGNLSGTS-FQQSPVRPSFTPALPA 3559
Query: 3892 QP 3893
P
Sbjct: 3560 AP 3561
Score = 295 bits (755), Expect = 9e-79
Identities = 174/481 (36%), Positives = 236/481 (49%), Gaps = 86/481 (17%)
Query: 5 KLAGEDKDSEPAADGPAASEDPSATESDLPNPHV-----GEVSVLSSGSPRLQETPQDCS 59
K A ED+DS DG +E + E+++ EV P LQ + + S
Sbjct: 60 KTAVEDEDS---MDGLETTETETIVETEIKEQSAEEDAEAEVDNSKQLIPTLQRSVSEES 116
Query: 60 GGPV-----------RRCALCNCGEPSLHGQRELRRFELP----FDWPRCPV-------- 96
+ + CA C CGE S GQ +L++F + W P
Sbjct: 117 ANSLVSVGVEAKISEQLCAFCYCGEKSSLGQGDLKQFRITPGFILPWRNQPSNKKDIDDN 176
Query: 97 ----------VSPGGSPGPNEAVLPSE-----------------------DLSQIGFPEG 123
+P G + P + +LS +G P+
Sbjct: 177 SNGTYEKMQNSAPRKQRGQRKERSPQQNIVSCVSVSTQTASDDQAGKLWDELSLVGLPDA 236
Query: 124 LTPAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGASIP 183
+ L + G+CWAHH C WS GV E P L VDKA+ SG ++RC+ C LGA+I
Sbjct: 237 IDIQALFDSTGTCWAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIK 296
Query: 184 CRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAYL--EEARCAVCEGPGELCDL 241
C C ++YH+PCA +G+F + LLCPEH + A E+A CAVC+ PG+L D
Sbjct: 297 CCEEKCTQMYHYPCAAGAGTFQDFSHIFLLCPEHIDQAPERSKEDANCAVCDSPGDLLDQ 356
Query: 242 FFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHTF 301
FFCT+CG HYHG CLD A+T KRAGWQCPECKVCQ C++ G DSKMLVC+TCDKGYHTF
Sbjct: 357 FFCTTCGQHYHGMCLDIAVTPLKRAGWQCPECKVCQNCKQSGEDSKMLVCDTCDKGYHTF 416
Query: 302 CLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENYSLCHRCHKAQG------G 355
CL+P M+ +P + WKCK CR+C CG S +S+W N +C C++ Q G
Sbjct: 417 CLQPVMKSVPTNGWKCKNCRICIECGTRS-----SSQWHHNCLICDNCYQQQDNLCPFCG 471
Query: 356 QTIRSVAEQ---HTPVCSRFSPPEPGDTPTD-EPDAL----YVACQGQPKGGHVTSMQPK 407
+ ++ H +C R+ E D PTD E D Y+ + G + +QP
Sbjct: 472 KCYHPELQKDMLHCNMCKRWVHLE-CDKPTDHELDTQLKEEYICMYCKHLGAEMDRLQPG 530
Query: 408 E 408
E
Sbjct: 531 E 531
Score = 131 bits (330), Expect = 2e-29
Identities = 72/219 (32%), Positives = 111/219 (50%), Gaps = 23/219 (10%)
Query: 1380 CVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRCVECIVCEVCGQASDP 1439
C VC S G + C+ C Q YH C++ +T + GW+C EC VC+ C Q+ +
Sbjct: 344 CAVCDSPGDLLDQFF--CTTCGQHYHGMCLDIAVTPLKRA-GWQCPECKVCQNCKQSGED 400
Query: 1440 SRLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQCGAASPGFHCEWQNSYTHCG 1499
S++L+CD CD YHT+CL P + +VP GWKCK C C++CG S +W ++ C
Sbjct: 401 SKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCRICIECGTRSSS---QWHHNCLICD 457
Query: 1500 PCASLV--TCPI---CHAPYVEEDLLIQCRHCERWMHAGCESLFTEDDVEQAADEGFDCV 1554
C CP C+ P +++D+L C C+RW+H C+ T+ +++ E + C+
Sbjct: 458 NCYQQQDNLCPFCGKCYHPELQKDML-HCNMCKRWVHLECDKP-TDHELDTQLKEEYICM 515
Query: 1555 SC----------QPYVVKPVAPVAPPELVPMKVKEPEPQ 1583
C QP +A + M+V+ PE Q
Sbjct: 516 YCKHLGAEMDRLQPGEEVEIAELTTDYNNEMEVEGPEDQ 554
Score = 116 bits (290), Expect = 7e-25
Identities = 54/129 (41%), Positives = 73/129 (56%), Gaps = 5/129 (3%)
Query: 224 LEEARCAVCEGPGELCD--LFFCTSCGHHYHGACLDTALTARKRA-GWQCPECKVCQACR 280
L + C VC G+ + L C+ CG YH C+ +T + GW+C EC VC+AC
Sbjct: 955 LNQDMCVVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKGWRCLECTVCEACG 1014
Query: 281 KPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWF 340
K + ++L+C+ CD YHT+CL PP++ +P WKCK C CR CGA SA L EW
Sbjct: 1015 KATDPGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGL--RCEWQ 1072
Query: 341 ENYSLCHRC 349
NY+ C C
Sbjct: 1073 NNYTQCAPC 1081
Score = 85.5 bits (210), Expect = 1e-15
Identities = 138/545 (25%), Positives = 198/545 (36%), Gaps = 88/545 (16%)
Query: 500 ESPLSPPPESSPFSPLE--------ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE 551
+SPL+P P + SP + + P S P + P +PPP +P P ++
Sbjct: 1807 QSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQD 1866
Query: 552 SPLSPPPEELPTSP---PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF------PP 602
S LS P SP P +S PP SPM P + PP F P
Sbjct: 1867 S-LSQAQTSQPPSPQVFSPGSSNSRPP---SPMDPYAKMVGTPRPPPVGHSFSRRNSAAP 1922
Query: 603 FEE-SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR--------- 652
E +PLS PL + P D S P + PP+ R
Sbjct: 1923 VENCTPLS--SVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPK 1980
Query: 653 ---LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS--------------RLSPPPED 695
LS PVVS + + P++ + T P P A L+P P D
Sbjct: 1981 SLGLSRSPVVSEQT---AKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLD 2037
Query: 696 SPTSPPPEDSPASPPP--EDSLMSLPLEESPLLPLP-EEPQLCPRSEGPHLSPRPEEPHL 752
S P P +P PPP +D S+ L P E P L PR + +P+
Sbjct: 2038 S--GPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYS 2095
Query: 753 SPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP--EEPHLSPQAEGPHLSPQP--EELHLSP 808
P P PH + H S +P + P ++P+ P +P+P + S
Sbjct: 2096 QP-PLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPG-----TPRPVVDSYSQSS 2149
Query: 809 QTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPP 868
T + P + P P + + P S++P +PRP S + P + R P
Sbjct: 2150 GTARSNTDPYSQPP---GTPRPTTVDPYSQQP-QTPRP--STQTDLFVTPVTNQRHSDPY 2203
Query: 869 EEPGQCPAPE-ELPLFPPPGEPSLSPLLGEP-ALSEPGEPPLSPLPEE-LPLSPSGEPSL 925
P P P +P PP P P + E S P L P + L + + P+L
Sbjct: 2204 AHPPGTPRPGISVPYSQPPATP--RPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPAL 2261
Query: 926 -SPQLMPPD-------PLPPPLSPIITAAAPPAL-SPLGELEYPFGAKGDSDPESPLAAP 976
P + PPD P P LS + +P A P + ++ DS S A
Sbjct: 2262 PGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHD 2321
Query: 977 ILETP 981
+ + P
Sbjct: 2322 VADQP 2326
Score = 84.0 bits (206), Expect = 4e-15
Identities = 137/609 (22%), Positives = 209/609 (34%), Gaps = 83/609 (13%)
Query: 528 PSPALETPLSPPPEASPLSP--PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPP 585
PS +++PL+P P +SP F + + P PTS S P +PPP
Sbjct: 1802 PSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTS------SDDVFVKPQAPPP 1855
Query: 586 EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS 645
+P P + S ++ S PP SP SR PP SPM P +
Sbjct: 1856 PPAPSRIPIQDS-----LSQAQTSQPPSPQVFSPGSSNSR--PP---SPMDPYAKMVGTP 1905
Query: 646 PPPEV----SRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPP 701
PP V SR + V +P S E + P P S ++
Sbjct: 1906 RPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAK 1965
Query: 702 PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL---SPRPE---------- 748
P D+P + SL L SP++ H SPR +
Sbjct: 1966 PPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDS 2025
Query: 749 --EPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA-EGPHLSPQPEELH 805
P L+P P + P P ++P LS E P L+P+P +
Sbjct: 2026 YARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNF 2085
Query: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP- 864
Q+ +P+ P P P + +H S +P RP +PP +PRP
Sbjct: 2086 SHNQSNDPYSQP-PLTPHPAVNESFAHPSRAFSQPGTISRPTS---QDPYSQPPGTPRPV 2141
Query: 865 -EKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP 923
+ + G + + P PPG P P +P +P P S + + +
Sbjct: 2142 VDSYSQSSGTARSNTD-PYSQPPGTP--RPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQR 2198
Query: 924 SLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDP-----ESPL----- 973
P PP P +S + + PPA +P + F + P + P
Sbjct: 2199 HSDPYAHPPGTPRPGIS--VPYSQPPA-TPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQ 2255
Query: 974 -AAPILETPISPPPEANCTDPEPVPPMILPP-SPGSPVGPASPILMEPLPPQC------S 1025
P L P+ PP+ P P P + S SP P P+ P+ +
Sbjct: 2256 NRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGT 2315
Query: 1026 PLLQHSLVPQNSPPSQ---CSPPALPL-----------SVPSPLSPIGKVVGVSDEAELH 1071
H + Q P S+ C+ P+ +P P+ P V + +
Sbjct: 2316 SQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPV-PTSGVTDTQNTVNMA 2374
Query: 1072 EMETEKVSE 1080
+ +TEK+ +
Sbjct: 2375 QADTEKLRQ 2383
Score = 76.3 bits (186), Expect = 8e-13
Identities = 188/860 (21%), Positives = 277/860 (32%), Gaps = 218/860 (25%)
Query: 395 QPKGGHVTSMQP--KEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPP 452
QP G+++ Q KE Q + P + + + +AP P P P P+
Sbjct: 1813 QPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAP-----PPPPAPSRIPIQDS 1867
Query: 453 PEESPTSPPPEASRLSP------PPEELPA--------SPLPEALHLSRPLEESPLSPPP 498
++ TS PP SP PP + P P SR +P+
Sbjct: 1868 LSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCT 1927
Query: 499 EESPLSPPPESSPFSPLEESPL---------------SPPEESPPSPALETPLSPPPEAS 543
S +S P + + + SP+ PP+ P + P S S
Sbjct: 1928 PLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRS 1987
Query: 544 PL-SPPFEESPLSPPPEELPTSPPPEAS--------------RLSPPPEESPMSPPPEES 588
P+ S + P++ + T P P A L+P P +S P P ++
Sbjct: 1988 PVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDS--GPGPFKT 2045
Query: 589 PMSPPP----------EASRLFP--PFEESPLSPPP-------------EESPLSPPP-- 621
PM PPP +ASR P+E L+P P + PL+P P
Sbjct: 2046 PMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAV 2105
Query: 622 ------------EASRLSPPPEDSPMSPPP-------------------EESPMSPPPEV 650
+ +S P P S PP P S PP
Sbjct: 2106 NESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGT 2165
Query: 651 SRLSPLPVVSRLSPPPEES--------PLSPPPEESPTSPPPEASR--LSPPPEDSPTSP 700
R + + S+ P S P++ P + PP R +S P P +P
Sbjct: 2166 PRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATP 2225
Query: 701 PPEDS----------PASPPPEDSLMSLPLEESPLLPLP--EEPQLC---PRSEGPHLS- 744
P S P P +D + P LP P P C PR GP LS
Sbjct: 2226 RPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSD 2285
Query: 745 ------------PRPEEPHLSPRPEEPHLSPQAEEPHLSPQP---EEPCLCAVPEEPHLS 789
P + P ++PR + ++ QP E CA P S
Sbjct: 2286 TFSRVSPSAARDPYDQSP-MTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHS 2344
Query: 790 PQAEGPHLSPQPEELHLSPQTEEP---HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846
+ +S P + S T+ +++ E Q + Q ++ ++ R
Sbjct: 2345 QGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQ 2404
Query: 847 EE-SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905
E+ S SP + P P PE Q PPP P + P
Sbjct: 2405 EKGSQDSPAVPHP--GPLQHWQPENVNQAFTR------PPPPYPG--------NIRSPVA 2448
Query: 906 PPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLG-ELEYPFGAK 964
PPL P P G P PP + A + P G +P G+
Sbjct: 2449 PPLGPRYAVFPKDQRG------------PYPPDV-------ASMGMRPHGFRFGFPGGSH 2489
Query: 965 GDSDPESPLAAP---ILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLP 1021
G + P I + +SP + + P P + +PVG L +
Sbjct: 2490 GTMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMPRP--LNNSQMNNPVG-----LPQHFS 2542
Query: 1022 PQCSPLLQHSLVPQNSPPSQCSPP----ALPLSVPSPLSPIGKVVGVSDEAELHEMETEK 1077
PQ P+ QH+++ Q + P LP S P G VV EA +
Sbjct: 2543 PQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPP-----GSVV----EASSNLRHGNF 2593
Query: 1078 VSEPECPALEPSATSPLPSP 1097
+ P+ P P T P+ P
Sbjct: 2594 IPRPDFPG--PRHTDPMRRP 2611
Score = 63.5 bits (153), Expect = 5e-09
Identities = 150/708 (21%), Positives = 238/708 (33%), Gaps = 153/708 (21%)
Query: 363 EQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKP---- 418
E TP+ S P + +T + P + C + P P P+ + P
Sbjct: 1924 ENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLG 1983
Query: 419 LGKAGVQLEPQLEAPL-------------------------NEEMPLLPP--------PE 445
L ++ V E + P+ + PLL P P
Sbjct: 1984 LSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPF 2043
Query: 446 ESPLSPPPE-ESPTSPPPEASR-LSPPPEELPA---SPLPEALH--LSRPLEESPLSPPP 498
++P+ PPP + P +ASR LS P E PA P+ H + P + PL+P P
Sbjct: 2044 KTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHP 2103
Query: 499 EESPLSPPPESSPFS-------PLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE 551
+ P S FS P + P S P +P P +++ A + P+ +
Sbjct: 2104 AVNESFAHP-SRAFSQPGTISRPTSQDPYSQPPGTP-RPVVDSYSQSSGTARSNTDPYSQ 2161
Query: 552 SPLSPPPEEL-PTSPPPEASRLSPPPE--ESPMSPPPEESPMSPPPEASR--LFPPFEES 606
P +P P + P S P+ R S + +P++ P + PP R + P+ +
Sbjct: 2162 PPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQP 2221
Query: 607 PLSPPPEES----------PLSPPPE-----ASRLSPPPEDSPMSPPPEESPMSPPPEVS 651
P +P P S P+ P + A++ P P+ PP+ +P P
Sbjct: 2222 PATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGP 2281
Query: 652 RLSPLPVVSRLSP-----PPEESPLSPPPEESPTSPPPEASRLSPPPE-----------D 695
LS SR+SP P ++SP++P + A ++ P +
Sbjct: 2282 GLSD--TFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSN 2339
Query: 696 SPTS------------PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743
SP P P + ++++ + L + ++ + +
Sbjct: 2340 SPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKK 2399
Query: 744 SPRPEEPHLSPRPEEPHLSP-------QAEEPHLSPQPEEPCLCAVPEEPHLSPQ-AEGP 795
+E P PH P + P P P P P L P+ A P
Sbjct: 2400 IAGRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFP 2459
Query: 796 HLSPQPEELHLSPQTEEPH------------LSPVPEEPCLSPQP-EESHLSPQSEEPCL 842
P ++ PH P E + PQ + S +SPQ
Sbjct: 2460 KDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVS 2519
Query: 843 SPRPEESHLSPELEKPPLSPRPEKPPEEP-------GQC------PAPE---ELPLFPPP 886
P + S ++ P P+ P P GQ AP+ LP PP
Sbjct: 2520 VDMPRPLNNS-QMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPP 2578
Query: 887 G---EPSLS---------PLLGEPALSEPGEPPLSPLPEELPLSPSGE 922
G E S + P P ++P P LP +LP+ P E
Sbjct: 2579 GSVVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLE 2626
Score = 61.2 bits (147), Expect = 3e-08
Identities = 37/108 (34%), Positives = 50/108 (46%), Gaps = 5/108 (4%)
Query: 122 EGLT--PAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLG 179
+GLT PA L W H CA WS V+ + L V+ A+ G+ +C C + G
Sbjct: 4410 DGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTG 4469
Query: 180 ASIPCRSPGCPRLYHFPCA-TASGSFLSMKTLQLLCPEHSEGAAYLEE 226
A+ C C +YHF CA A F KT +LCP H + +E
Sbjct: 4470 ATSGCHRFRCTNIYHFTCAIKAQCMFFKDKT--MLCPMHKPKGIHEQE 4515
Score = 60.1 bits (144), Expect = 6e-08
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 5057 WVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYHFA 5116
W H C WS V + + L+NV+ A+ G +C+ C+ GAT C +C +YH+
Sbjct: 250 WAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQMYHYP 309
Query: 5117 CAIRA-KCMFFKDKTMLCPMHKIKGP 5141
CA A F +LCP H + P
Sbjct: 310 CAAGAGTFQDFSHIFLLCPEHIDQAP 335
Score = 57.4 bits (137), Expect = 4e-07
Identities = 114/478 (23%), Positives = 167/478 (34%), Gaps = 76/478 (15%)
Query: 3896 SLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQ---LQQQQQQQQLQQQQQQQLQQQQ 3952
S+++ QQQ + ++ + + +Q++ + +Q +QQ +Q+ QQ + + Q+ +
Sbjct: 1715 SMKRQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLE 1774
Query: 3953 QQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSP 4012
Q +QQQQQQQQF Q Q G S + SP Q G G P Q F
Sbjct: 1775 QVKNEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQP-----GNG-NMSPAQSFH-- 1826
Query: 4013 GALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVK-PSLSG 4071
KE T P + +T + P++ P + P
Sbjct: 1827 -----------KELFTKQPPSTPTSTSSDD--------VFVKPQAPPPPPAPSRIPIQDS 1867
Query: 4072 DSQLLLVQPQPQPQ---PSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEAS 4128
SQ QP P PQ P S +PP + + + G S + S A+
Sbjct: 1868 LSQAQTSQP-PSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNS-----AA 1921
Query: 4129 SVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNN----TGPQPPKPGPVLQSGQG 4184
V + SVS Q T N P + + NN P P+P Q +
Sbjct: 1922 PVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKS 1981
Query: 4185 LPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQ 4244
L G+ P V + A +G +A P +A + QRQ R Y
Sbjct: 1982 L-GLSRSPVVSEQTA--KGPIAAGTSDHFTKPSP----RADVFQRQ-------RIPDSYA 2027
Query: 4245 EPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRP-----QGPPRLPAPP---GAL 4296
P +PL PGP P+Q + P Q RL P AL
Sbjct: 2028 RPLLTPAPLD----------SGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPAL 2077
Query: 4297 STGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354
+ P+ H Q P P + S P+ A P P Q P +PP
Sbjct: 2078 TPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPP 2135
Score = 50.1 bits (118), Expect = 6e-05
Identities = 42/171 (24%), Positives = 60/171 (35%), Gaps = 51/171 (29%)
Query: 189 CPRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAYLEEARCAVCEGPGELCD---LFFCT 245
C + YH C +S+K +++ S+G LE C VCE G+ D L C
Sbjct: 980 CGQCYHPYC-------VSIKITKVVL---SKGWRCLE---CTVCEACGKATDPGRLLLCD 1026
Query: 246 SCGHHYHGACLDTALTARKRAGWQCPECKVCQAC-------------------------- 279
C YH CLD L + GW+C C C+ C
Sbjct: 1027 DCDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAPCASLSS 1086
Query: 280 -----RKPGNDSKMLVCETCDKGYHTFC----LKPPMEELPAHSWKCKACR 321
R + +L C CD+ H C + +E + + C CR
Sbjct: 1087 CPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCR 1137
Score = 47.0 bits (110), Expect = 5e-04
Identities = 195/917 (21%), Positives = 307/917 (33%), Gaps = 172/917 (18%)
Query: 2039 SSRCKQIMKLWRKVPAAD----KAPYLQKAKDNRAAHRINKVQKQAESQIN----KQTKV 2090
S++ + K R+ P D K Q++ + +I K QK+ I KQ +
Sbjct: 3213 SAKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQ 3272
Query: 2091 GDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSV 2150
+A T P++ + P PGA +PP + PT P P L + +
Sbjct: 3273 CAMAPPTMMPSVQPQPPLIPGA--TPPTMSQPTF----PMVPQQLQHQQHTTV------I 3320
Query: 2151 PGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPP 2210
G SP + P +P P+ P L PL P P P P T PA
Sbjct: 3321 SGHTSPVRM-----PSLPGWQPNSAPAHL----PLNP--PRIQPPIAQLPIKTCTPAPGT 3369
Query: 2211 MLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKP--------------RCPSLDNLA 2256
+ A+ + G EF P + Q L+ R +L
Sbjct: 3370 VSNANPQSGPPPRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVDRQRALQQRM 3429
Query: 2257 VPESPGVGGGKASEPLLS-----------PPPFGESRKALEVKKEELGASSPSYGPPNL- 2304
E G+ G + S S P F + L+ + N+
Sbjct: 3430 EMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQ 3489
Query: 2305 -GFVDSPSSGTHLGGLELK-------TPDVFKAPL-TPRASQVEPQSPGL-GLRPQEPPP 2354
G ++SPS+ T + E + PD P+ +P S V+ L G Q+ P
Sbjct: 3490 QGSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPV 3549
Query: 2355 AQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ--PPPPESCCALPPRSLPSDPF---- 2408
+ P+ P+ P + + + P Q P +S L +P +
Sbjct: 3550 RPSFTPALPAAPPV---ANSSLPCGQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKR 3606
Query: 2409 SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHK 2468
+R S+++P TP S P+P S S P PQ D + +
Sbjct: 3607 TRKKKRDDDAESTKAPSTPH--SDITAPPTPGISETTSTPAVSTPSELPQQADQESV--E 3662
Query: 2469 PPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQ----PPN---FVRS 2521
P P P +A AG L EL K+P+ PN + S
Sbjct: 3663 PVGPSTPNMA--AGQLCT------------------ELENKLPNSDFSQATPNQQTYANS 3702
Query: 2522 PGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYT 2581
+ TP+ E P +P L +G G + P S+
Sbjct: 3703 EVDKLSMETPAKTE-EIKLEKAETESCPGQEEPKLEEQNGSKVE---GNAVACPVSS--- 3755
Query: 2582 VATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSP 2641
A H +G+P L + S L P+GS+ + +
Sbjct: 3756 -AQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSIC-----SEDDCTKDNK 3809
Query: 2642 VEKREDPGTGM---GSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRN 2698
+ ++++P G+ G+ + G Q P G S+T+ ++ ++ QR E + +R
Sbjct: 3810 LVEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRK 3869
Query: 2699 TLRQEKETAAAA-------------AGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDK 2745
+EK+ ++ + PP S P A ++++ G FA T++
Sbjct: 3870 KDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANG---FATTEEL 3926
Query: 2746 SSLVGLPPSKLSGPILGPGSF-----PSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQ 2800
+ G+ S LGP F P DD L+R P ++DV
Sbjct: 3927 AGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQG-PKTVDV-------------- 3971
Query: 2801 RAPYPGSLPL---QQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGI 2857
P SLP Q++ Q T F S+ S G E+ R +
Sbjct: 3972 ----PASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSR------YPDL 4021
Query: 2858 STRLPGPGEPVPGPAGP 2874
S P EPVP P P
Sbjct: 4022 SLVKEEPPEPVPSPIIP 4038
Score = 45.1 bits (105), Expect = 0.002
Identities = 101/484 (20%), Positives = 174/484 (35%), Gaps = 68/484 (14%)
Query: 4506 PSNKEDAAARK-PLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPL 4564
PS++ D+ K PL + ++ R+K +++ + A++ L +Q+K E
Sbjct: 1727 PSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKL-EQVKNEQQQQQQ 1785
Query: 4565 TEPAITANFSLFAPFGSGCPVNG-QSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPP 4623
+ + L GS P +G QS L G+G + ++ +L TK S P +
Sbjct: 1786 QQ---FGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTS 1842
Query: 4624 SS------LPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLL 4677
S P PPP+ + + + + P + S + R S + +
Sbjct: 1843 SDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNS-RPPSPMDPYAKM 1901
Query: 4678 AALPTPPHNQTEDVRMESDEDSDSPDSIVPASSP----ESILGEEAPRFPHLGSGRWEQE 4733
P PP R S ++ + S P E+ +P S +
Sbjct: 1902 VGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
Query: 4734 DRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAA 4793
A P P PV D P +LGL + PV + + KG ++A +
Sbjct: 1962 PYAKPPDTPR------PVMTDQFP-KSLGL---SRSPVVSEQTAKG-------PIAAGTS 2004
Query: 4794 KNLNGVMVAVAELLSMKIPNSY-EVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDT 4852
+ +IP+SY L +P +G P K + P +
Sbjct: 2005 DHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQD--------- 2055
Query: 4853 GPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPE 4912
P ++ LS+ E PA P ++++N SN Q PP
Sbjct: 2056 ------------PYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQ----PPL 2099
Query: 4913 EPSPPPSPLAPSPASPPTEP-LVELPT--EPLAEPP-VPSPLPLASSPESARPK----PR 4964
P P + P+ ++P + PT +P ++PP P P+ + S S + P
Sbjct: 2100 TPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPY 2159
Query: 4965 ARPP 4968
++PP
Sbjct: 2160 SQPP 2163
Score = 45.1 bits (105), Expect = 0.002
Identities = 112/602 (18%), Positives = 189/602 (31%), Gaps = 92/602 (15%)
Query: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET 534
P PL ++ + + + ++ ++ P + E + PP P SP++
Sbjct: 3465 PLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDSPSI-- 3522
Query: 535 PLSPPPEASPLS-------PPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE 587
P+ P +S F++SP+ P + PP A+ P ++S ++
Sbjct: 3523 PVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTIT----- 3577
Query: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647
S P L + + PEE + E + P +PP
Sbjct: 3578 HGHSYPGSTQSLIQLYSDII----PEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPP 3633
Query: 648 -PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSP------PPEDSPTSP 700
P +S + P VS S P+++ P++P A +L P D +
Sbjct: 3634 TPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQAT 3693
Query: 701 PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL----------------- 743
P + + A+ + M P + + E + CP E P L
Sbjct: 3694 PNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPV 3753
Query: 744 SPRPEEPHLSPRPEE---------PHLSPQAEEPHLSPQPEEPCLCA-----------VP 783
S PH + P HL + L Q E +C+
Sbjct: 3754 SSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEK 3813
Query: 784 EEPHLSPQAEGPHLS---------PQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLS 834
+ P Q G + P+ + + + E+ +P+ ++
Sbjct: 3814 QNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEK--AAPRSKKRKKD 3871
Query: 835 PQSEEPCLSPRPEESHLSPE--LEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLS 892
+ ++ S +HL + L PP P P P C G +
Sbjct: 3872 EEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMAN-------GFATTE 3924
Query: 893 PLLGEPA--LSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD----PLPPPLSPIITAA 946
L G+ +S L P P +LP P + P P P P
Sbjct: 3925 ELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQGPKTVDVPASLPTPPHNNQE 3984
Query: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETP-ISPPPEANCTDPEPVPPMILPPSP 1005
G+ + P S PES + + P +S E PEPVP I+P P
Sbjct: 3985 ELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKE---EPPEPVPSPIIPILP 4041
Query: 1006 GS 1007
+
Sbjct: 4042 ST 4043
Score = 42.0 bits (97), Expect = 0.017
Identities = 110/497 (22%), Positives = 167/497 (33%), Gaps = 94/497 (18%)
Query: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP--R 746
++PP P P P + PP MS P P++P + Q H SP
Sbjct: 3275 MAPPTMMPSVQPQPPLIPGATPPT---MSQPT--FPMVPQQLQHQQHTTVISGHTSPVRM 3329
Query: 747 PEEPHLSPRPEEPHL--SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP--------- 795
P P P HL +P +P ++ P + C A + +PQ+ P
Sbjct: 3330 PSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEFDDNN 3389
Query: 796 ----HLSPQPEELHLSPQTEEPHLSPVPE---EPCLSPQPE-ESHLSPQSE----EPCLS 843
+ + L Q E + + E + L + E E H SE +S
Sbjct: 3390 PFSESFQERERKERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVS 3449
Query: 844 PRPEESHLSPELEKPPLSPRPEKPP--EEPGQCPAPEELPLFPPPGEPSLSPLLGEPALS 901
P S P PL P + P ++ GQ + + PS +
Sbjct: 3450 QIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQ-GSINSPSTQTFMQTNERR 3508
Query: 902 EPGEPPLSPLPEELPL-SPS------GEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPL 954
+ G P P +P+ SP+ G +LS P+ P +P + AA P A S L
Sbjct: 3509 QVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSL 3568
Query: 955 ---------------------------------GELEYPFGAKGDSDPESPLAAPILETP 981
G+ + K D D ES A +
Sbjct: 3569 PCGQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSD 3628
Query: 982 ISPPPEANCTDPEPVP----PMILPPSPG----SPVGPASP-ILMEPLPPQCSPLLQHSL 1032
I+ PP ++ P P LP PVGP++P + L + L +S
Sbjct: 3629 ITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSD 3688
Query: 1033 VPQNSPPSQ--CSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSA 1090
Q +P Q + LS+ +P ++E +L + ETE E P LE
Sbjct: 3689 FSQATPNQQTYANSEVDKLSMETPAK--------TEEIKLEKAETESCPGQEEPKLEEQN 3740
Query: 1091 TSPLPSPMGDLSCPAPS 1107
S + ++CP S
Sbjct: 3741 GSKVEG--NAVACPVSS 3755
Score = 40.4 bits (93), Expect = 0.049
Identities = 123/603 (20%), Positives = 192/603 (31%), Gaps = 123/603 (20%)
Query: 3862 QQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQ 3921
++ QQQ S+ S + L + + S +Q+ + +QQ + + +QQ +++
Sbjct: 1717 KRQQQQDSIDPSSRIDSELFKDPLKQRESEH--------EQEWKFRQQMRQKSKQQAKIE 1768
Query: 3922 QQQQLQQQQLQQQQQQQQLQQQQQQQLQQQ-----QQQLQQQQQQQQQQFQQQQQQQQMG 3976
Q+L+Q + +QQQQQQ Q Q L Q +Q Q Q
Sbjct: 1769 ATQKLEQVK-NEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHK 1827
Query: 3977 LLNQSRTLLSPQQQQQQQVALGPGMPAKP-----------LQHFSSPGALGPTLLLTG-- 4023
L + +P V + P P P L + P + G
Sbjct: 1828 ELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSS 1887
Query: 4024 --KEQNTVDPAVSSEATEGP--------------STHQGGPLAIGTTP----ESMATEPG 4063
+ + +DP T P PL+ + P E+ A P
Sbjct: 1888 NSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPS 1947
Query: 4064 EVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGS 4123
V+ S + +P P + + G + V TA G + +G+
Sbjct: 1948 PVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTA----KGPIAAGT 2003
Query: 4124 SSEASSVPHLLAQPSVSLGDQ---PGSMTQNLLGPQQPMLERPMQNNTGPQPPKP----- 4175
S + P + + P S + LL P P+ P T QPP
Sbjct: 2004 SDHFTK-----PSPRADVFQRQRIPDSYARPLLTP-APLDSGPGPFKTPMQPPPSSQDPY 2057
Query: 4176 GPVLQSGQGL-------PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQ 4228
G V Q+ + L P + P Q ++ P H + + +
Sbjct: 2058 GSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFS 2117
Query: 4229 RQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRP----- 4283
+ S+ Q P Q PGT + ++ Q G T P + PRP
Sbjct: 2118 QPGTISRPTSQDPYSQPPGTP----RPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDP 2173
Query: 4284 -QGPPRLPAPPGA--LSTGPVLGPVHPTP------------------PPSSPQ------- 4315
P+ P P L PV H P PP++P+
Sbjct: 2174 YSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGF 2233
Query: 4316 ---EPKRPSQLPSPSSQLPTEAQLPPTHPG-----------TPKPQGPTLEPPPGRVSPA 4361
RP +P+ L P PG TP+P GP L RVSP+
Sbjct: 2234 TRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPS 2293
Query: 4362 AAQ 4364
AA+
Sbjct: 2294 AAR 2296
Score = 37.0 bits (84), Expect = 0.55
Identities = 80/323 (24%), Positives = 114/323 (35%), Gaps = 73/323 (22%)
Query: 4028 TVDPAVSSEATEGPSTHQG---GPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQP 4084
TVDP T PST P+ + A PG +P +S + QP P
Sbjct: 2170 TVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGIS----VPYSQPPATP 2225
Query: 4085 QP------SSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPS 4138
+P + + P+ +P Q + G G L + S P P
Sbjct: 2226 RPRISEGFTRSSMTRPVLMPNQDPF-LQAAQNRGPALPGPLVRPPDT-CSQTPR---PPG 2280
Query: 4139 VSLGDQPGSMTQNLLGP---QQPMLERPMQNNTGPQP--------PKPG----------- 4176
L D ++ + Q PM R ++ G P+PG
Sbjct: 2281 PGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNS 2340
Query: 4177 PVLQSGQGLPGV----GIMPTVGQLRAQ--LQGVLAKNPQLRHLSPQQQQQLQALLMQRQ 4230
P+ GQ GV G +PT G Q + A +LR Q+Q+L+ +++Q+Q
Sbjct: 2341 PMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLR-----QRQKLREIILQQQ 2395
Query: 4231 LQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLP 4290
Q+ A R QE G+Q SP P GPLQ Q R P
Sbjct: 2396 QQKKIAGR-----QEKGSQDSPAV--------------PHPGPLQHWQPENVNQAFTRPP 2436
Query: 4291 AP-PGALST--GPVLGPVHPTPP 4310
P PG + + P LGP + P
Sbjct: 2437 PPYPGNIRSPVAPPLGPRYAVFP 2459
Score = 35.4 bits (80), Expect = 1.6
Identities = 60/263 (22%), Positives = 83/263 (31%), Gaps = 48/263 (18%)
Query: 394 GQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPP 453
G+ + G S PGPLQ +P P P N P+ PP P
Sbjct: 2402 GRQEKGSQDSPAVPHPGPLQ-HWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPK 2460
Query: 454 EESPTSPP------------------------PEASRLSPPPEELPASPLPEALHLSRPL 489
++ PP P R PP+++ S + L S +
Sbjct: 2461 DQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSV 2520
Query: 490 E-ESPLSPPPEESPLSPPPESSPFS-PLEESPLSPP-----EESPPSPALETPLSPPP-- 540
+ PL+ +P+ P SP S P+++ + P P S PP
Sbjct: 2521 DMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGS 2580
Query: 541 --EAS-----------PLSP-PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE 586
EAS P P P P+ PP+ LP P PP +
Sbjct: 2581 VVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVH 2640
Query: 587 ESPMSPPPEASRLFPPFEESPLS 609
S M L F E+PLS
Sbjct: 2641 SSSMVMRTLNHPLGGEFSEAPLS 2663
Score = 33.9 bits (76), Expect = 4.6
Identities = 61/278 (21%), Positives = 98/278 (35%), Gaps = 44/278 (15%)
Query: 3665 PGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQ 3724
PG G ++ Q Q G L GP + + G Q
Sbjct: 2328 PGSEGSFCASSNSPMHSQGQQFSGVSQLPGP----------VPTSGVTDTQNTVNMAQAD 2377
Query: 3725 QQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQG 3784
++++ QKL++ QQQQQ+ + G+ ++ Q P V P P P +
Sbjct: 2378 TEKLRQRQKLREIILQQQQQKKIAGRQ--EKGSQDSPAVP-----HPGPLQHWQPEN--- 2427
Query: 3785 LLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQG 3844
+ Q + PP P + P P GP V R P +A G
Sbjct: 2428 -VNQAFTRPPPPYPGNIRSP------------VAPPLGPRYAVFPKDQRGPYPPDVASMG 2474
Query: 3845 Q-------GLMGHRLVTAQQQQQQQQHQQQGSMAGLS-HLQQSLMSHSGQPKLSAQ---P 3893
G G T Q++ QQ +G+S L++S+ +P ++Q P
Sbjct: 2475 MRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNP 2534
Query: 3894 MGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQL 3931
+G Q Q QQ + Q +L+ + +Q+L
Sbjct: 2535 VGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRL 2572
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 221 bits (563), Expect = 2e-56
Identities = 260/1044 (24%), Positives = 399/1044 (38%), Gaps = 213/1044 (20%)
Query: 357 TIRSVAEQHTPVCSRFSPPEPGDTPTDEPDAL-YVACQGQPKGGHVTSMQPKEPGPLQCE 415
T + A TP+ + SP P + ++L + + P H + + P
Sbjct: 810 TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869
Query: 416 AKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESP----TSPPPEASRLSPPP 471
PL GV L P+ E P + LP P+E P +P P+++P TS P+ +R +P P
Sbjct: 870 VTPLSPKGVTLPPK-ETP-TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAP 927
Query: 472 EELPASPLPEALHL----------SRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLS 521
+ +PASP P+ P SP P + P P+ P +P + +
Sbjct: 928 KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT 987
Query: 522 PPEESPPSP----------ALETP--LSPP-PEASPLSPPFEESPLSPP----------- 557
PP +PPSP TP ++PP P+ SP + PF + +PP
Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047
Query: 558 -----PEELPTSP---------------------PPEASRLSPPPEESPMSPPPEESPMS 591
P+ PT+P PP A+ P P+ P +P P+ +PM
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT--PPSPKGGPATPSPKGAPMP 1105
Query: 592 PP-----PEASRLFPPFEESPLSP--------------PPEESPLSPP-----PEASRLS 627
P P+ PP + +P +P PP+ +P +P P+ +
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165
Query: 628 PPPEDSPMSPPPEESPMSPPPEVSRLSP--LPVVSRLSPP-PEESPLSPPPEESPTSPP- 683
PPP+ +P +P +P SP ++ SP P +PP P+ +P P+ +PT+P
Sbjct: 1166 PPPKGAPTTPAA--TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 684 ----PEASRLSPPPEDSPTSPP-----PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734
P+ +P P+ +PT+P P+ PA+PPP+ + P P
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA--------------PTPPAA 1269
Query: 735 CPRSEGPHLSPRPEEPHLSPR---PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQ 791
P S L+ P + +P P P P P +P P A P P SP
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP----AATPPSPKGSPG 1325
Query: 792 AEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHL 851
P +P P P P P P +P + +P S+E P SH
Sbjct: 1326 TPPPKGAPTP------PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK 1379
Query: 852 S------PELEKPPLSPRPEKPPEEPGQCP-APEELPLFPPPGEPSLSPLLGE---PALS 901
P ++ P P P+ P P P +P++ P P E + +P G+ PA++
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439
Query: 902 EPG--EPPLSPLPEELPLSPS--GEPSLSPQLMPPDPLPPPL-SPIITAAAP-------- 948
+ P + P+ P +PS G+P+L P + PP P PP + T+++P
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTL-PAVTPPSPKEPPAPKQVATSSSPKKAPATPA 1498
Query: 949 -------PALSPLGELEYPFGAKGDSDPESPLAAPILE-TP--ISP-----PPEANCTDP 993
PA+ P E P DP +P A + + TP ++P PP P
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP 1558
Query: 994 EPVPPMILP---PSPGSPVGPASPILMEPLPPQCSPLLQHSLVP----QNSPPSQCSPPA 1046
+ P + P P+ S +SP + P + +P + L+P SP +PPA
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPA 1618
Query: 1047 L--PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECP----ALEPSATSPLPSPMGD 1100
+ P P +P K S ++ S A P A+ LP+ G
Sbjct: 1619 VTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678
Query: 1101 ------LSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVL 1154
L PAP P + + G T +P P+P GS KG
Sbjct: 1679 TALKEVLVAPAPESTPIITAPTRKGPQTKK-SSATSPPICPDPSAKNGS-----KGP--- 1729
Query: 1155 LDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAP------TPPTLIKSDIVNEI 1208
L+ V P + P K ++ + P+ P+AP TP T + V
Sbjct: 1730 -----LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK 1784
Query: 1209 SNLSQGDASASFPGSEPLLGSPDP 1232
+ A+ S P S PL SP P
Sbjct: 1785 PESASVSAAPSPPVSLPLAPSPVP 1808
Score = 202 bits (515), Expect = 6e-51
Identities = 280/1032 (27%), Positives = 394/1032 (38%), Gaps = 207/1032 (20%)
Query: 416 AKPLGKAGVQLEPQLEAPLNE----EMPLLPPPEES-PLSPPPEESPTSPPPEASRLSPP 470
A P + V L P+ P+ E +PL+P E+ P++P P+ T P L+P
Sbjct: 673 ASPFLEGTVSLAPK-NHPVKEGTLTTLPLVPTASENCPVAPSPQN--TCAPLATLVLAPE 729
Query: 471 -PEELPASPLPEA------------LHLS--RPLEESPLSPPPEESPLSPPPES-SPFSP 514
P+ +P+ LP A H S P+ SP P E+S S S +
Sbjct: 730 IPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTY 789
Query: 515 LEESP------LSPPEESPP----SPALETPL----SP--PPEASPL---SPPFEESPLS 555
L +SP +SP + PP S +TP+ SP P EAS L S F+ S S
Sbjct: 790 LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDS 849
Query: 556 PPPEELPTSPPPEASRLSPPPEESPMSP-----PPEESPMSPPPEASRLFPPFEESPLSP 610
P PT P P+ + P +P+SP PP+E+P P + FP +E P +P
Sbjct: 850 PATTHSPTPPSPKGA--PTPSAVTPLSPKGVTLPPKETP--TPSVVNLPFP--KEGPATP 903
Query: 611 PPEESP----LSPPPEASRLSPPPEDSPMSP-------PPEESPMSPPPEVSRLSP--LP 657
P+++P S P+ +R +P P+ P SP PP +P SP + SP P
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
Query: 658 VVSRLSPP-PEESPLSPPPEESP-----TSPPPEASRLSPPPEDSP-----TSPPPEDSP 706
+PP P+ P +P P+ +P T P P+ +P P+ +P T P P+ SP
Sbjct: 964 TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Query: 707 ASPP-------PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEP 759
A+ P P + P PLP+ P + P P P L P P
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083
Query: 760 HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819
+P P P P P P +P + L+ P H T P P
Sbjct: 1084 AATP----PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP---HKGAPTTPAATPPSP 1136
Query: 820 EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG-QCPAPE 878
+ +P P+ + +P + P P+ +P + P +P P + G P+P+
Sbjct: 1137 KGGLATPPPKGAPTTPAA----TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPK 1192
Query: 879 ELPLFPPPGEPSLSPLLGEP----ALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDP 934
P P PS L P A + P P SP SP G P+ +P PP P
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT-TPAATPPSP 1251
Query: 935 L------PPPLSPIITAAAPPAL-----------SPLGELEYPFGAKGDSDPESPLAAPI 977
PP +P AA PP+L +P + P KG P AP
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311
Query: 978 LETPISPPPEANCTDP----EPVPPMILPPSP-GSPV----------GPASPILME-PLP 1021
P P+ + P P PP + PPSP G+P GP +P E P P
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
Query: 1022 PQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVS-DEAELHEMETEKVSE 1080
P +P H P +PPS PA+P P SP V+ +S +A + E +
Sbjct: 1372 PAATP--SHKGGPAMTPPSPKRGPAIPSPKGDPTSP--AVIPLSPKKAPATPVTREGAAT 1427
Query: 1081 PECPALEPSATSPL-----------------PSPMGDLSCPA---PSP------------ 1108
P L P A +P+ PS GD + PA PSP
Sbjct: 1428 PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS 1487
Query: 1109 -----APALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLD---PEEL 1160
APA + +G T P P S E TP S + + LL P L
Sbjct: 1488 SSPKKAPATP--APMGAPTLP---AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL 1542
Query: 1161 AP----VTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKS---------DIVNE 1207
AP + P P K+T +P E P + A +PP + S +++
Sbjct: 1543 APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602
Query: 1208 ISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPET 1267
+ S A P P + P PE G + G T SP SL+ DS P +
Sbjct: 1603 PAVTSPSPKEAPTP---PAVTPPSPEKGPATPAPKG--TPTSPPVTPSSLK---DS-PTS 1653
Query: 1268 DDSLLCDAGTAI 1279
S+ C G +
Sbjct: 1654 PASVTCKMGATV 1665
Score = 192 bits (487), Expect = 1e-47
Identities = 244/924 (26%), Positives = 358/924 (38%), Gaps = 144/924 (15%)
Query: 373 SPPEPGDTPTDEP-----DALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLE 427
+PP P +P P A PKGG T P P P K G
Sbjct: 1039 TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP-PAATPPSPKGG---- 1093
Query: 428 PQLEAPLNEEMP--LLPPPEESPLSPPPEE------SPTSPPPEASRLSPPPEELPASPL 479
P +P MP PP + L+ PP + + T P P+ +PPP+ P +P
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
Query: 480 PEALHLSRPLEESPLS-PPPEESPLSPP-----PESSPFSPLEESPLSPPEESPPSP--- 530
+ P + L+ PPP+ +P +P P+ +P + + P +PPSP
Sbjct: 1154 A-----TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 531 -ALETPLSPP--PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE 587
A +P P P A+P SP + +P P+ PT+P + P P+ P +PPP+
Sbjct: 1209 LATPSPKGAPTTPAATPPSP--KGGLATPSPKGAPTTP----AATPPSPKGGPATPPPKG 1262
Query: 588 SPMSP---PP--EASRLFPPFEESP----LSPP-PEESPLSPPPEAS-----RLSPPPED 632
+P P PP + PP + +P ++PP P+ P + PP+ + P P+
Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322
Query: 633 SPMSPPPEESPMSPPPEVSRLSP--LPVVSRLSPPPEESPLSPPPEESPTSPPPEASR-- 688
SP +PPP+ +P PP V+ SP P + +P + P +P +E PT P S
Sbjct: 1323 SPGTPPPKGAPT--PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380
Query: 689 ---LSPP-PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLS 744
++PP P+ P P P+ P SP +++ L +++P P+ E P S+G
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSP----AVIPLSPKKAPATPVTREGAATP-SKGDLTP 1435
Query: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV-PEEPHLSPQAEGPHLSPQPEE 803
P L + P S P +P L AV P P P + S P++
Sbjct: 1436 PAVTPVSLK---KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492
Query: 804 LHLSPQTEEPHLSP-----VPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE--LE 856
+P T P +P +P P P S P + L + + L+P+ L
Sbjct: 1493 ---APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI 1549
Query: 857 KPPLS-PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL------GEPALSEPGEPPL- 908
P ++ P P+K P P P+E P P E S P + G P+ E PP
Sbjct: 1550 PPAMTVPSPKKTPA----IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAV 1605
Query: 909 -SPLPEELPLSPSGEPSLSPQLMPPDPLPP--PLSPIIT-------------------AA 946
SP P+E P P+ P SP+ P P P P SP +T A
Sbjct: 1606 TSPSPKEAPTPPAVTPP-SPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGAT 1664
Query: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG 1006
P A L + P K +P + PI+ P P+ + P P +
Sbjct: 1665 VPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKN 1724
Query: 1007 SPVGPASPILMEPLPP--QCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGV 1064
GP S + PL P + S +SP +PP S P + KV+
Sbjct: 1725 GSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK 1784
Query: 1065 SDEAELHEMETEKVSEPECPALEPSATSP-----LPSPMG-DLSCPAPSPAPALDD---- 1114
+ A + + VS P P+ P T P LPS G L P+ APA +D
Sbjct: 1785 PESASVSAAPSPPVSLPLAPS--PVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP 1842
Query: 1115 ------FSGLGEDTAPLDGIDAPGSQPEPGQTPGS---LASELKGSPVLLDPEELAP-VT 1164
SG + L + P S P TP + + KGS D +E P +
Sbjct: 1843 LIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELE 1902
Query: 1165 PMEVYPECKQTAGQGSPCEEQEEP 1188
+ Q A + E EEP
Sbjct: 1903 EQDSTQATTQQAQLAAAAEIDEEP 1926
Score = 150 bits (379), Expect = 3e-35
Identities = 248/976 (25%), Positives = 321/976 (32%), Gaps = 143/976 (14%)
Query: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAG--LSTSADGFLKPPAGSVPGP-DSPGELFLKL 2163
P G SP P APT +P +P G + S PPA + P P P K
Sbjct: 925 PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG 984
Query: 2164 PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223
P PA P G PA P PT P P PSP G+PA P +S P A P
Sbjct: 985 APTPPAATPPSPKGG--PATPSPKGAPTPPAVTP--PSPKGSPAATPFPKGASTPPAATP 1040
Query: 2224 GEFHTTPPGT--PRHQPST-----PDPFLKPRCPSLDNLAVPES---PGVGGGKASEPLL 2273
+P T P+ P+T P P P PSL P + P GG A
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA----- 1095
Query: 2274 SPPPFGESRKALEVKKEELG--ASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPL 2331
+P P G G A+ P G P PS GG L TP AP
Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP---KGG--LATPPPKGAPT 1150
Query: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
TP A+ P SP GL PP + +P + P + G T P TP PP
Sbjct: 1151 TPAAT---PPSPKGGL---ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Query: 2392 PESCCALP-PRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPY 2450
P+ A P P+ P+ P + P SP+ + TP P A P TP P P
Sbjct: 1205 PKGGLATPSPKGAPTTP-AATPPSPKGGLA-----TPSPKGA------PTTPAATPPSPK 1252
Query: 2451 SRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKV 2510
P + P P P PP + K G GA P P G
Sbjct: 1253 GGPATPPPKGAPTPPAATPP-------SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305
Query: 2511 PSG-------QPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP----------- 2552
P G PP+ SPGT G P+P T P G P+L P
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365
Query: 2553 QPGLPPPHGINSHFG----------PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTG 2602
+ G PP SH G GP + P+ + A P +P P +
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGA 1425
Query: 2603 ESYGLSPLRPPSVLP---PPAPDGSLPY------LSHGASQRSGITSPVEKREDPGTGMG 2653
+ L PP+V P AP S P S G +T P K +
Sbjct: 1426 ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVA 1485
Query: 2654 SSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAA-- 2711
+S + + P T P + + + R I K+T A A
Sbjct: 1486 TSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPK 1545
Query: 2712 GAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGP------ILGPG- 2764
A+ PP P + +++ SS + PS G ++ P
Sbjct: 1546 EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAV 1605
Query: 2765 SFPSDDRLSRPP----------------------PPATPSSMDVNSRQLVGGSQAFYQRA 2802
+ PS PP PP TPSS+ + +
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665
Query: 2803 PYPG-SLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPL----AGI 2857
P LP ++ L + A A S + P+ GP+ + + SP
Sbjct: 1666 PQASKGLPAKKGPTALKEVLVAPAPESTPIITA---PTRKGPQTKKSSATSPPICPDPSA 1722
Query: 2858 STRLPGPGEPV-PGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRL 2916
GP V P P P Q + KG +P PP+ P++
Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQ--KDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEK 1780
Query: 2917 APEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRP 2976
+VS P S P AP S PT K LP+ LV PS +P
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLAP----SPVPTLPPKQQFLPSSPGLVLESPS-----KP 1831
Query: 2977 NPLALEAGKLPCEDPE 2992
A E LP PE
Sbjct: 1832 LAPADEDELLPLIPPE 1847
Score = 150 bits (378), Expect = 4e-35
Identities = 301/1240 (24%), Positives = 411/1240 (33%), Gaps = 210/1240 (16%)
Query: 2116 PPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQD 2175
P P APT +P +P G++ P P P F K P PA P Q
Sbjct: 859 PSPKGAPTPSAVTPLSPKGVTL--------PPKETPTPSVVNLPFPKEGPATPA--PKQA 908
Query: 2176 P-FGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPG-EFHTTPPG- 2232
P + + P + R AP P PSP GAP P S + G P ++ TPP
Sbjct: 909 PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 2233 ---TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG------GGKASEPLLSPPPFGESRK 2283
+P+ P+TP P P P+ A P SP G G + P ++PP S
Sbjct: 969 TPPSPKGGPATPSPKGAPTPPA----ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 2284 ALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ-S 2342
A K GAS+P P SP G TP AP TP A+ P+
Sbjct: 1025 ATPFPK---GASTPPAATP-----PSPK------GSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 2343 PGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP-R 2401
P P P A PSP P P P+ P PP P+ A PP +
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPATPSPKG-------APMPPAATPPSPKGGLATPPHK 1123
Query: 2402 SLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRD 2461
P+ P + P SP+ + TP P A P TP P P + P
Sbjct: 1124 GAPTTP-AATPPSPKGGLA-----TPPPKGA------PTTPAATPPSPKGGLATPPPKGA 1171
Query: 2462 PFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPN-FVR 2520
P P PP P K G + GA PAA P P G L P G P
Sbjct: 1172 PTTPAATPPSP-------KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1224
Query: 2521 SPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQ--PGLPPPHGINSHFGPGPTLGKPQST 2578
P + TPSP A P+ PP P+ P PPP G P P P S
Sbjct: 1225 PPSPKGGLATPSP-----KGAPTTPAATPPSPKGGPATPPPKG-----APTPPAATPPSL 1274
Query: 2579 NYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGI 2638
+AT + +P + S SP P PPA P S G G
Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSP--PKGAPTPPAATPPSPKGSPGTPPPKGA 1332
Query: 2639 TSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRN 2698
+P P S T LP T P G T K+
Sbjct: 1333 PTP------PAVTPPSPKGTPTLPAT-TPSSKGGPTTPSSKE-----------------G 1368
Query: 2699 TLRQEKETAAAAAGAVGPPG--------SWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVG 2750
+ A+ PP S +P+SPA LS + P + +
Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT- 1427
Query: 2751 LPPSK--LSGPILGPGSFPSDDRLSRPP-PPATPSSMDVNSRQLVGGSQAFYQRAPYPGS 2807
PSK L+ P + P S S P PATPSS + A +P
Sbjct: 1428 --PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPT------LPAVTPPSPKEPP 1479
Query: 2808 LPLQQQQQQLWQQQQATAATSMRFAMSARFPSTP-----GPELGRQALGSPLAGISTRLP 2862
P Q ++ AT A + A PS+P P R + +S + P
Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539
Query: 2863 GPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSED---PHRLAPE 2919
P PA + P P P+ P S++ P + P
Sbjct: 1540 ATLAPKEALIPPAMTV-----------PSPKKTPAIPTPKEAPATPSSKEASSPPAVTPS 1588
Query: 2920 GLRGL----------AVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPP- 2968
+G AV+ P++ PPA + P KGP P PP
Sbjct: 1589 TYKGAPSPKELLIPPAVTSPSPKEAPTPPA------VTPPSPEKGPATPAPKGTPTSPPV 1642
Query: 2969 -SSTELGRPNPLALEAGKLPCEDPELDDDFDAHKALEDDEEL----AHLGLGVDVAKGDD 3023
S+ P A K+ P+ A K +E+ A + A
Sbjct: 1643 TPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRK 1702
Query: 3024 ELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAERE 3083
T ++ T+ P DP G K + + + + +
Sbjct: 1703 GPQTKKSSATSPP--------------ICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKT 1748
Query: 3084 ALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEP 3143
A + P GP PP + AS P A+ +V PK E +P +P V
Sbjct: 1749 AKGKDASHSPKGP--LAPPESKASTPLTAAAFEKVLPKPESASVSAAP------SPPVS- 1799
Query: 3144 APAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSG 3203
P A S L P Q + S + P K A L+ P P+SG
Sbjct: 1800 LPLAPSPVPTLPPKQQFLPSSPGLVLESP--------SKPLAPADEDELLPLIPPEPISG 1851
Query: 3204 --PGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQ 3261
P S L+ +S + +P P+A + S S+ + +L E + +
Sbjct: 1852 GVPFQSVLVNMPTPKSAGIPVP-TPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQAT 1910
Query: 3262 KKQ-QLSA-------QLQPAQQQQQQQQQHSLLSAPGPAQ 3293
+Q QL+A + A+Q + +++ +S G Q
Sbjct: 1911 TQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQ 1950
Score = 143 bits (361), Expect = 4e-33
Identities = 232/906 (25%), Positives = 334/906 (36%), Gaps = 138/906 (15%)
Query: 442 PPPEESPLSPPPEESPTS------PPPEASRLSPPPEELPASP-LPEALHLSRPLEESPL 494
PP P+S SP + P E S +P SP LP+ L L S L
Sbjct: 465 PPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKN-LPSSVL 523
Query: 495 SPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPL 554
P + L P S LE +P SP + + T L A SP F+ +
Sbjct: 524 VKFPTQKDLQTVPAS-----LEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSS 578
Query: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPEE--SPMSPPPEASRLFPPFEESPLSPPP 612
SP E+P SP ++ S E P+ P SP+ AS + P S P
Sbjct: 579 SP---EIPLSPEATLAKKSLG-EPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGP 634
Query: 613 E-ESPLSPPPEASRLSPPPEDSPMSPPPEE-------------------SPMSPPPEVSR 652
+S L P A+ + + ++P + +P + P +
Sbjct: 635 LLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGT 694
Query: 653 LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE 712
L+ LP+V S E P++P P+ T P + L PE + P P PA PP
Sbjct: 695 LTTLPLVPTAS---ENCPVAPSPQN--TCAP--LATLVLAPEIPKSVPSPSLPPAGTPPG 747
Query: 713 DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL-----SPRPEEPHLSPQAEE 767
+ S L P+ P+ CP + + + L SP P +SPQ +
Sbjct: 748 TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR 807
Query: 768 PHLS-------------PQPEEPCLCAVPEEPHL-------------SPQAEGPHLSPQP 801
P P P + E L SP P +P P
Sbjct: 808 PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTP 867
Query: 802 EEL-HLSPQ--TEEPHLSPVPEEPCLSPQPEESHLSPQSEE-PCL---SPRPEESHLSPE 854
+ LSP+ T P +P P L P P+E +P ++ P L S P+++ +P
Sbjct: 868 SAVTPLSPKGVTLPPKETPTPSVVNL-PFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926
Query: 855 LEKPPLSPRPEKPPEEPGQC-PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPE 913
+ P SP P+ P P P+P+ P P P P P+ P P +P P+
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS---PKGGPATPSPK 983
Query: 914 ELPLSPSGEPSLSPQLMP--PDPLPPPLSPIITAAAP---PALSPLGE-LEYPFGAKGDS 967
P P+ P SP+ P P P P P +T +P PA +P + P A S
Sbjct: 984 GAPTPPAATPP-SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS 1042
Query: 968 DPESPLAAPILE----TPIS--PPPEANCTDPE----PVPPMILPPSPGSPVGPASPILM 1017
SP A P+ + TP + P P+ P P PP PPSP GPA+P
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG--GPATPSPK 1100
Query: 1018 -EPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSP----LSPIGKVVGVSDEAELHE 1072
P+PP +P + +PP + +P + PSP +P K + A
Sbjct: 1101 GAPMPPAATPPSPKGGLA--TPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1158
Query: 1073 METEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPG 1132
+ + P A A +P PSP G L+ P+P AP + +P G+ P
Sbjct: 1159 PKGGLATPPPKGAPTTPAATP-PSPKGGLATPSPKGAPT----TPAATPPSPKGGLATPS 1213
Query: 1133 SQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPV 1192
+ P TP + KG P+ AP TP P K G P P
Sbjct: 1214 PKGAP-TTPAATPPSPKGGLATPSPKG-APTTPAATPPSPK-----GGPA----TPPPKG 1262
Query: 1193 APTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTD--VSP 1250
APTPP + ++ A + ++ P P+GG + S G T +P
Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAP-----NPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317
Query: 1251 ARDEGS 1256
+GS
Sbjct: 1318 PSPKGS 1323
Score = 133 bits (334), Expect = 6e-30
Identities = 274/1156 (23%), Positives = 382/1156 (33%), Gaps = 242/1156 (20%)
Query: 1916 GSRTPLQRPFLQGGLPLGNLPSSSPM--DSYPGLCQS-PFLDSR---ERGGFFSPEPGEP 1969
G P+ +P PLG S+S + DSY G + P L S F E +P
Sbjct: 596 GEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADP 655
Query: 1970 D--SPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANIN 2027
+P T G +T +T +P EG SL + G L+T+ V A+ N
Sbjct: 656 AGVAPTTAKGTSTYTTTASPFLEGTV--------SLAPKNHPVKEGTLTTLPLVPTASEN 707
Query: 2028 FPNLKQDYPDWSSRCKQI--MKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQIN 2085
P P + C + + L ++P + +P L A +++ + +
Sbjct: 708 CPVA----PSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSA---- 759
Query: 2086 KQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKP 2145
+A P P + + + ++ +P G+S S P
Sbjct: 760 -------LAPVASSPK---ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809
Query: 2146 PAGSVPGPDSP-GELFLKLPPQVPAQVPSQ--------------------DPFGL---AP 2181
GPD+P G L + P + +P P G +
Sbjct: 810 TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869
Query: 2182 AYPLEPRFPTAPPTYPPYPS-----------PTGAPAQPPMLGASSRPGAGQPGEFHTTP 2230
PL P+ T PP P PS T AP Q P L +S P + TP
Sbjct: 870 VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS----SSPKKARATP 925
Query: 2231 PGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKE 2290
P+ P++P P P P+ A P SP GG P +P P
Sbjct: 926 --APKGIPASPSPKGAPTPPA----ATPPSP-KGGPATPSPKWAPTP------------- 965
Query: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ-SPGLGLRP 2349
P+ PP SP G TP AP P A+ P+ P
Sbjct: 966 ------PAATPP------SPKGGP-------ATPSPKGAPTPPAATPPSPKGGPATPSPK 1006
Query: 2350 QEPPPAQALAPSPPSHPDI--FRPGSYTDPYAQPP-------LTPRPQPPPPESCCALP- 2399
P P PSP P F G+ T P A PP TP P+ P LP
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066
Query: 2400 PRSLPSDPFSR---VPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456
P+ P+ P + P + S P TP P A P+ P P P +
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA------PMPPAATPPSPKGGLATP 1120
Query: 2457 PQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPP 2516
P P P PP P K G GA PAA P P G L P G P
Sbjct: 1121 PHKGAPTTPAATPPSP-------KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT 1173
Query: 2517 N-FVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKP 2575
P + TPSP A P+ PP P+ GL P + P T P
Sbjct: 1174 TPAATPPSPKGGLATPSP-----KGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT---P 1225
Query: 2576 QSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRP-----PSVLPPPAPDGSLPYLSH 2630
S +AT + P G+P P++ G + P P PP+ G L H
Sbjct: 1226 PSPKGGLATPS--PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283
Query: 2631 GASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELL 2690
+ + +P + P T T P P G T K
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTP--PAATPPSPKGSPGTPPPK----------- 1330
Query: 2691 IRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVG 2750
A AV PP G P+ PA S+G +++ +
Sbjct: 1331 ----------------GAPTPPAVTPPSPKGT-PTLPATTPSSKGGPTTPSSKEGPTPPA 1373
Query: 2751 LPPSKLSGPILGPGSFPSDDR-LSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLP 2809
PS GP + P PS R + P P P+S P +P
Sbjct: 1374 ATPSHKGGPAMTP---PSPKRGPAIPSPKGDPTS---------------------PAVIP 1409
Query: 2810 LQQQQQQLWQQQQATAATSMRFAMS---------ARFPSTPGPELG---RQALGSPLAGI 2857
L ++ + AAT + ++ + P+T P+ G + G P
Sbjct: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469
Query: 2858 STRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHR-- 2915
T P P EP P P A + P G P P P+ P + R
Sbjct: 1470 VTP-PSPKEP-PAPKQVATSSSPK-KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDP 1526
Query: 2916 LAPEG--LRGLAVSGLPPQKPSAPPA-----PELNNSLHPTPHTKGPTLPTGLELVNRPP 2968
+AP L + L P++ PPA P+ ++ PTP + P P+ E + PP
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAI-PTP-KEAPATPSSKE-ASSPP 1583
Query: 2969 S---STELGRPNPLAL 2981
+ ST G P+P L
Sbjct: 1584 AVTPSTYKGAPSPKEL 1599
Score = 108 bits (270), Expect = 1e-22
Identities = 123/466 (26%), Positives = 188/466 (40%), Gaps = 87/466 (18%)
Query: 367 PVCSRFSPPEPGDTPTDEPDALYV---------ACQGQPKGGHVTSMQPKE-PGPLQCEA 416
P +PP P + P + A A G P V PKE P
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524
Query: 417 KPLGKAGVQLEPQLEAPLNEEMPLLPP------PEESPLSPPPEESPTSPPPEASRLSPP 470
P+ L + A L + L+PP P+++P P P+E+P +P + S P
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP--SSKEASSP 1582
Query: 471 PEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSP 530
P P++ + P + L PP + SP P+ +P +PP +PPSP
Sbjct: 1583 PAVTPST------YKGAPSPKELLIPP---AVTSPSPKEAP---------TPPAVTPPSP 1624
Query: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPM 590
+ P +P P+ +P SPP S L ++ PTSP ++ ++ P ++ P
Sbjct: 1625 E-KGPATPAPKGTPTSPPVTPSSL----KDSPTSPASVTCKMGATVPQASKGLPAKKGPT 1679
Query: 591 SPPPEASRLFPPFEESPLSPPPEESPLSPPP--------EASRLSPPPEDSPMSPPPEES 642
+ +E ++P PE +P+ P ++S SPP P + +
Sbjct: 1680 A-----------LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728
Query: 643 PMS---PPP--EVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS---RLSPPPE 694
P+S P P V + S + + + PL+PP ES S P A+ ++ P PE
Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPP--ESKASTPLTAAAFEKVLPKPE 1786
Query: 695 DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSP 754
+ S P SPP +SLPL SP+ LP + Q P S G L P +P L+P
Sbjct: 1787 SASVSAAP-----SPP-----VSLPLAPSPVPTLPPKQQFLPSSPGLVLE-SPSKP-LAP 1834
Query: 755 RPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE-----PHLSPQAEGP 795
E+ L EP P + L +P P +P A+ P
Sbjct: 1835 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880
Score = 102 bits (253), Expect = 1e-20
Identities = 220/872 (25%), Positives = 313/872 (35%), Gaps = 165/872 (18%)
Query: 453 PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES------PLSPPPEESPLSPP 506
P E+ + P L P E P+ AL ++ L + P SP P++ PLS
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 507 PESSPF---SPLEESPLSPP-EESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP 562
++SPF S + +PL P +S AL PL PEA P P+SP L
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTAL--PLGTAPEAPTFLPNLIGPPISPAALAL- 118
Query: 563 TSPPPEASRLSPPPEESPM-SPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621
SPM +P + +P S P A P S P SPP
Sbjct: 119 ---------------ASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPS 163
Query: 622 EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS 681
A S S +P++P + L+ +P S + P P+ +P PP T
Sbjct: 164 VAVAESG-------SVITLSAPIAPSEPKTNLNKVP--SEVVPNPKGTP--SPPCIVSTV 212
Query: 682 P----PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPR 737
P P AS S T+P + ASP +D+ +S L + P+
Sbjct: 213 PYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVL-------------ISPQ 259
Query: 738 SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797
+ G P P P LS Q+ S Q A P P P + G HL
Sbjct: 260 NPGSLSLKGPVSP-----PAALSLSTQSLPVVTSSQK-----TAGPNTPPDFPISLGSHL 309
Query: 798 SPQPE----ELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSP 853
+P + + L QT LS P +S + S S+ + P P + + P
Sbjct: 310 APLHQSSFGSVQLLGQTGPSALSD-PTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVP 368
Query: 854 ELEK--PPLSPRPEKPPEEPGQ--CPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLS 909
P ++P +K P C L + SLSP S P
Sbjct: 369 ATVAAFPVVAPSVDKGPSTISSITCSPSGSLNV---ATSFSLSPTTSLILKSSPNATYHY 425
Query: 910 PLPEELPLSPSG-EPSLSPQLMPPDPLPPPLSPIITAAAPPALS-PLGELEYPFGAKGDS 967
PL ++P+S G P + P + T +PP S P+ +E A
Sbjct: 426 PLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVM 485
Query: 968 DPESP-----LAAPILETPISPPPEANCTDPEP---VPPMILPPSP-------------G 1006
P +P A L P+SPP DPE +P +L P G
Sbjct: 486 APVAPKEPSTQVATTLRIPVSPP----LPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEG 541
Query: 1007 SPVGPASPILMEPLPPQCSPLLQHSLVPQNSP--PSQCSPPALPLSVPSPLS-------- 1056
+P PA L P PL+Q P+NSP S S P +PLS + L+
Sbjct: 542 APFSPAQAGLTTKKDPTVLPLVQ--AAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPL 599
Query: 1057 PIGK-------VVGVSDEAELHEMETEKVSEPECPALEPSATSP----LPSPMGDLSCPA 1105
PIGK +GV+ A + + ++ + P L+ S +P P D + A
Sbjct: 600 PIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVA 659
Query: 1106 PSPAPALDDF----SGLGEDTAPLDGIDAPGSQPEPGQTPGSL---ASELKGSPVLLDPE 1158
P+ A + S E T L AP + P T +L + + PV P+
Sbjct: 660 PTTAKGTSTYTTTASPFLEGTVSL----APKNHPVKEGTLTTLPLVPTASENCPVAPSPQ 715
Query: 1159 E-LAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNL------ 1211
AP+ + + PE ++ P P A TPP K D ++ S L
Sbjct: 716 NTCAPLATLVLAPEIPKSV---------PSPSLPPAGTPPGTKKVDGISHTSALAPVASS 766
Query: 1212 --------SQGDASASFPGSEPLLG-SPDPEG 1234
S A+AS G+ L SP P G
Sbjct: 767 PKECPTEDSGASATASSKGTLTYLADSPSPLG 798
Score = 87.0 bits (214), Expect = 5e-16
Identities = 212/916 (23%), Positives = 321/916 (35%), Gaps = 142/916 (15%)
Query: 449 LSPP--PEESPTSPPPEASRLSPPPEELPASPLPEAL---HLSRPLE--ESPLSPPPEES 501
LS P P E T+ S + P P+ P+ P + H P+ +S ++ P+ +
Sbjct: 175 LSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT 234
Query: 502 PLSPPPESSPFSPLEESPLSPPEESPPSP---ALETPLSPPPEASPLS---PPFEESPLS 555
P + +SP ++++ +S SP +P +L+ P+SPP S + P S +
Sbjct: 235 PTTTLAIASP--QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKT 292
Query: 556 PPPEELPTSPPPEASRLSPPPEESPMS------------PPPEESPMSPPPEASRLFPPF 603
P P P S L+P + S S P +S ++ P
Sbjct: 293 AGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPS 352
Query: 604 EESPLSPPPEESPLSPPPEASR--LSPPPEDSPMS--------------------PPPEE 641
+ S + P P + + P A+ ++P + P + P
Sbjct: 353 QRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTS 412
Query: 642 SPMSPPPEVSRLSPLPV---VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT 698
+ P + PL VS + P +PT+ A+ +SPP P
Sbjct: 413 LILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPI 472
Query: 699 SPPPEDSPAS------PPPEDSLM---SLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE 749
S SPA+ P E S +L + SP LP PE+ + P S L P +
Sbjct: 473 SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSV---LVKFPTQ 529
Query: 750 PHLSPRPEEPHLSP-QAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSP 808
L P +P + L+ + + L V P SP + SP E+ LSP
Sbjct: 530 KDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSP---EIPLSP 586
Query: 809 QTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPP 868
+ S EP +P S SP S +S+ P+ P L P
Sbjct: 587 EATLAKKS--LGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPT 644
Query: 869 EEPGQCPAPEELPLFPPPGE------PSLSPLL-GEPALSEPGEPPLSPLPEELPLSPSG 921
+ + + P + + SP L G +L+ P LPL P+
Sbjct: 645 VAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTA 704
Query: 922 EPSLSPQLMPPDPLPP----PLSPIITAAAP-PALSPLGELEYPFGAKGDSDPESPLAAP 976
+ P + P L+P I + P P+L P G P K D + AP
Sbjct: 705 SENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG--TPPGTKKVDGISHTSALAP 762
Query: 977 ILETPISPPPE---ANCT------------DPEPV-----PPMILPPSPGSPVGPASPI- 1015
+ +P P E A+ T P P+ P PP+ GP +PI
Sbjct: 763 VASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG 822
Query: 1016 -LMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEME 1074
L P+ P ++ S +P+NS Q S + P + SP P K G + + +
Sbjct: 823 NLSSPVSP-----VEASFLPENSLSFQGSKDS-PATTHSPTPPSPK--GAPTPSAVTPLS 874
Query: 1075 TEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSG---LGEDTAPLDGIDAP 1131
+ V+ P PS + LP P + PAP APAL S T GI A
Sbjct: 875 PKGVTLPPKETPTPSVVN-LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS 933
Query: 1132 GSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECK----QTAGQGSPCEEQEE 1187
S P + KG P P + AP P P K + +G+P
Sbjct: 934 PSPKGAPTPPAATPPSPKGGPATPSP-KWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT 992
Query: 1188 PRAPV----------APTPPTLIKSDIVNEISNLSQGDASASFP--GSEPLLGSPDPEGG 1235
P +P APTPP + + A+ FP S P +P G
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTP-------PSPKGSPAATPFPKGASTPPAATPPSPKG 1045
Query: 1236 GSLSMELGVSTDVSPA 1251
+ L +PA
Sbjct: 1046 SPAATPLPKGAPTTPA 1061
Score = 87.0 bits (214), Expect = 5e-16
Identities = 247/1084 (22%), Positives = 348/1084 (32%), Gaps = 211/1084 (19%)
Query: 4000 GMPAKPLQHFS-SPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESM 4058
G+PA P + +P A P G + A + A PS +GGP +P+
Sbjct: 929 GIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP-KGGPAT--PSPKGA 985
Query: 4059 ATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQ 4118
T P PS G P P+ P+ PP P + + G S
Sbjct: 986 PTPPAATPPSPKGGP----ATPSPKGAPT-----PPAVTPPSPKGSPAATPFPKGASTPP 1036
Query: 4119 LGSGSSSEASSVPHLLAQ-----PSVSLGDQPGSMTQNLLGPQQPMLE-RPMQNNTGPQP 4172
+ S + S L + P+ +L G GP P L+ P P
Sbjct: 1037 AATPPSPKGSPAATPLPKGAPTTPAATLPSPKG-------GPATPSLKGAPTPPAATPPS 1089
Query: 4173 PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQ 4232
PK GP S +G P MP + +G LA P
Sbjct: 1090 PKGGPATPSPKGAP----MPPAATPPSP-KGGLATPPH---------------------- 1122
Query: 4233 QSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELG--AGPRPQGPPRLP 4290
+ P T SP +G L P G P P G A P P+G P P
Sbjct: 1123 ------KGAPTTPAATPPSP-KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
Query: 4291 A-----PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPG--- 4342
A P G L+T G PT P ++P PK PSP T A PP+ G
Sbjct: 1176 AATPPSPKGGLATPSPKGA--PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233
Query: 4343 TPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQV 4402
TP P+G P SP KG GP PP A T + G L
Sbjct: 1234 TPSPKGAPTTPAATPPSP-----------KG-GPATPPPKGAPTPPAATPPSLKGGLATP 1281
Query: 4403 NGQVVPEASQL---SIKQEPREEPCALGAQSVKREANGEPIGAPGT-----SNHLLLAGP 4454
+ P + + S K P P GA + P G+PGT + P
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSP-PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340
Query: 4455 RSEAGHLLLQKLLRAKNVQLSTGRGSEGLR--AEINGHIDSKLAGLEQKLQGTPSNKEDA 4512
S G L + +T EG A H +G P+ +
Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH------------KGGPAMTPPS 1388
Query: 4513 AARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITAN 4572
R P P PK + + S KK R E K +L+ +T ++
Sbjct: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR--EGAATPSKGDLTPPAVTPVSLKKA 1446
Query: 4573 FSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSL-PPTPP 4631
+ AP G + + + P P Q+ T ++ P P+ + PT P
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506
Query: 4632 ----------PSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALP 4681
P+ + + P+ L K A+ E + V S A+P
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSK-KTPATLAPKEALIPPAMTVPSPKKTPAIP 1565
Query: 4682 TPPHNQTEDVRMESDEDSDSPDSIVP-----ASSPESILGEEAPRFPHLGSGRWEQEDRA 4736
TP E S +++ SP ++ P A SP+ +L A P
Sbjct: 1566 TPK----EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP------------- 1608
Query: 4737 LSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVT--TWEKGKGSEVSVMLTVSAAAAK 4794
SP P A P P+ P P PVT + + S SV + A +
Sbjct: 1609 -SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667
Query: 4795 NLNGVMV-----AVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPG---------- 4839
G+ A+ E+L P S ++ +P R G + KK A P
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPII--TAPTRKGPQTKKSSATSPPICPDPSAKNG 1725
Query: 4840 -------------------------GKEKGLEGKSPDTGPD-------WLKQFDAVLP-- 4865
GK+ K P P+ F+ VLP
Sbjct: 1726 SKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKP 1785
Query: 4866 --GYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAP--PPEE----PSPP 4917
+ +SL SP P P + + + L + S P P +E P P
Sbjct: 1786 ESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIP 1845
Query: 4918 PSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
P P+ S P LV +PT A PVP+P S+ + + E D P
Sbjct: 1846 PEPI--SGGVPFQSVLVNMPTPKSAGIPVPTP----SAKQPVTKNNKGSGTESDSDESVP 1899
Query: 4978 RLKK 4981
L++
Sbjct: 1900 ELEE 1903
Score = 86.3 bits (212), Expect = 8e-16
Identities = 249/1072 (23%), Positives = 339/1072 (31%), Gaps = 172/1072 (16%)
Query: 3999 PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTP-ES 4057
P + A PL+ G T T T P + + P H + T P
Sbjct: 643 PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVP 702
Query: 4058 MATEPGEVKPSLSGD----SQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGG 4113
A+E V PS + L+L P+ PS PP P ++ + HT+
Sbjct: 703 TASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSL--PPAGTPPGTKKVDGISHTSAL 760
Query: 4114 GSHGQL-------GSGSSSEASSVPHL--LAQPSVSLGDQPGSMTQN------LLGPQQP 4158
SG+S+ ASS L LA LG T+ GP P
Sbjct: 761 APVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP 820
Query: 4159 M--LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQL--QGVLAKNPQLRHL 4214
+ L P+ P+ Q + P PT + V +P+ L
Sbjct: 821 IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTL 880
Query: 4215 SPQQQQ--QLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQ-LGGFPGPQT 4271
P++ + L ++ + A +Q P T +SP + P+ + P P+
Sbjct: 881 PPKETPTPSVVNLPFPKEGPATPAPKQAPALSM--TSSSPKKARATPAPKGIPASPSPKG 938
Query: 4272 GPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLP 4331
P P P+G P P+P A PTPP ++P PK PSP
Sbjct: 939 APTPPAATPPSPKGGPATPSPKWA-----------PTPPAATPPSPKGGPATPSPKGAPT 987
Query: 4332 TEAQLPPT---HPGTPKPQG----PTLEPPPGRVSPAAAQLADTLFSKGLG------PWD 4378
A PP+ P TP P+G P + PP + SPAA T F KG P
Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA-----TPFPKGASTPPAATPPS 1042
Query: 4379 PPDNLAETQKPEQSSLVPGHL--DQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREAN 4436
P + A T P+ + P G P S+K P P A A
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATP-----SLKGAP-TPPAATPPSPKGGPAT 1096
Query: 4437 GEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLA 4496
P GAP A P S G L A +T +G G
Sbjct: 1097 PSPKGAPMPP----AATPPSPKGGLATPPHKGAPTTPAATPPSPKG------GLATPPPK 1146
Query: 4497 GLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLK 4556
G TP + + A TP PK S K L
Sbjct: 1147 GAPTTPAATPPSPKGGLA----TPPPKGAPTTPAATPPSPK-----------GGLATPSP 1191
Query: 4557 QELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPT--GPDYYSQLLTKN 4614
+ P P + L P G P + G A P+ G +
Sbjct: 1192 KGAPTTPAATPP-SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250
Query: 4615 NLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSL 4674
P TPP PTPP + + G+ G P A S + TS K
Sbjct: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA-PNPAVVTPPSPKGGPATSPPKGA 1309
Query: 4675 DL-LAALPTPPHNQ--TEDVRMESDEDSDSPDS-----IVPASSPESILG------EEAP 4720
AA P P T + + +P S +PA++P S G +E P
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369
Query: 4721 RFP-----HLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVT-TW 4774
P H G P IP P+ P P P P K P T
Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRGPAIP-SPKGD-PTSPAVIPLS------PKKAPATPVT 1421
Query: 4775 EKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGE 4834
+G + LT A +L A P+S P PA PK
Sbjct: 1422 REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG--DPTLPAVTPPSPK--- 1476
Query: 4835 AEGPGGKEKGLEG---KSPDT-GPDWLKQFDAVLPG------YTLKSQLDIL----SLLK 4880
E P K+ K+P T P AV+P T S+ D + +LL
Sbjct: 1477 -EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535
Query: 4881 QESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEP 4940
+++PA P + L P PSP +P P+P P P + + P
Sbjct: 1536 KKTPATLAPKE-------------ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582
Query: 4941 LAEPP-----VPSPLPLASSPESARPKPRARP---------PEEGEDSRPPR 4978
A P PSP L P P P+ P PE+G + P+
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK 1634
Score = 75.5 bits (184), Expect = 1e-12
Identities = 113/451 (25%), Positives = 176/451 (39%), Gaps = 92/451 (20%)
Query: 865 EKPPEEPGQCPAPE-ELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP 923
E P + P P+ E + P S++ LG+P + P PP SP P++ PLS + +
Sbjct: 7 ETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLP--PPCSPAPQQCPLSAANQA 64
Query: 924 SLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPIS 983
S P P SP A+ P LE PF P+S + P+
Sbjct: 65 S---------PFP---SPSTIASTP--------LEVPF-------PQSSSGTAL---PLG 94
Query: 984 PPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPL---PPQCSPLLQHSLVPQNSPPS 1040
PEA P +P +I PP + + ASP++ L P +PL +L P + S
Sbjct: 95 TAPEA----PTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKS 150
Query: 1041 QCSPPALPLSVPS-PLSPIGKVVGVS-------DEAELHEMETEKVSEPECPALEPSATS 1092
PP L S PS ++ G V+ +S + L+++ +E V P+ P S
Sbjct: 151 SAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVS 210
Query: 1093 PLP----SPM-----GDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGS 1143
+P +PM G S P +P L S +DT + +P Q PGS
Sbjct: 211 TVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISP-------QNPGS 263
Query: 1144 LASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAP--------- 1194
L+ LKG PV + V ++TAG +P + + +AP
Sbjct: 264 LS--LKG-PVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSV 320
Query: 1195 -----TPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVS 1249
T P+ + V IS + AS+P ++ P P + + V+
Sbjct: 321 QLLGQTGPSALSDPTVKTIS-VDHSSTGASYPSQRSVI-PPLPSRNEVVPATVAAFPVVA 378
Query: 1250 PARDEGSLRLCTDSLPETDDSLLCDAGTAIS 1280
P+ D+G P T S+ C +++
Sbjct: 379 PSVDKG---------PSTISSITCSPSGSLN 400
Score = 69.3 bits (168), Expect = 1e-10
Identities = 223/997 (22%), Positives = 302/997 (30%), Gaps = 194/997 (19%)
Query: 4043 THQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQ---PPLRLP- 4098
+H + ++P+ TE + S L + P P S+ Q PP +
Sbjct: 755 SHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGS 814
Query: 4099 -------GQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQ- 4150
G VS + A L S ++ + H PS P ++T
Sbjct: 815 AGPDTPIGNLSSPVSPVE-ASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPL 873
Query: 4151 NLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIM---PTVGQLRAQLQGVLAK 4207
+ G P E P + PK GP + + P + + P + +G+ A
Sbjct: 874 SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS 933
Query: 4208 N-----PQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQ 4262
P +P + A + A TPP + G T
Sbjct: 934 PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA--TPPSPKGGPAT------------ 979
Query: 4263 LGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHP--------------T 4308
P P+ P P P+G P P+P GA T P + P P T
Sbjct: 980 ----PSPKGAPTPPAATPPSPKGGPATPSPKGA-PTPPAVTPPSPKGSPAATPFPKGAST 1034
Query: 4309 PPPSSPQEPK-RPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLAD 4367
PP ++P PK P+ P P T A P+ G P P P +P + +
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
Query: 4368 TLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIK-----QEPREE 4422
S P P A P+ P H P A+ S K P+
Sbjct: 1095 ATPSPKGAPMPPA---ATPPSPKGGLATPPHK---GAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 4423 PCALGAQSVKRE---ANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRG 4479
P A + A P GAP T A P S G L A +T
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTP----AATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Query: 4480 SEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKL 4539
+G G G TP + + A TP PK S K
Sbjct: 1205 PKG------GLATPSPKGAPTTPAATPPSPKGGLA----TPSPKGAPTTPAATPPSPKGG 1254
Query: 4540 RKEDGVRASE----ALLKQLKQELSLLP---LTEPAITANFSLFAPFGSGCPVNGQSQLR 4592
+ + A LK L+ P PA+ P G P S +
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT-----PPSPKGGPAT--SPPK 1307
Query: 4593 GA-FGSGALPTGPDYYSQLLTKNNLSNPP-----TPPSSLPPTP------PPSVQQKMVN 4640
GA A P P K + PP TPP+ PP+P P +
Sbjct: 1308 GAPTPPAATPPSP--------KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359
Query: 4641 GVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTED---------- 4690
TPS + G P A + A+ S + A+P+P + T
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG----PAIPSPKGDPTSPAVIPLSPKKA 1415
Query: 4691 ----VRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLG----SGRWEQEDRALSPVIP 4742
V E D PA +P S+ A P G S + + A++P P
Sbjct: 1416 PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSP 1475
Query: 4743 LIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVA 4802
P A V + P A P P T S V T S+ +
Sbjct: 1476 KEPPAPKQVATSSSPKKAPATPAPMGAP-TLPAVIPSSPKEVPATPSSR-----RDPIAP 1529
Query: 4803 VAELLSMKIPNSY---EVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQ 4859
A LLS K P + E L P PA PKK A P KE S +
Sbjct: 1530 TATLLSKKTPATLAPKEALIP--PAMTVPSPKKTPAI-PTPKEAPATPSSKE-------- 1578
Query: 4860 FDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS 4919
A PP TY AP P+E PP+
Sbjct: 1579 -------------------------ASSPPAVTPSTYK---------GAPSPKELLIPPA 1604
Query: 4920 PLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSP 4956
+PSP PT P V P P P P+P +SP
Sbjct: 1605 VTSPSPKEAPTPPAV-TPPSPEKGPATPAPKGTPTSP 1640
Score = 60.1 bits (144), Expect = 6e-08
Identities = 164/741 (22%), Positives = 256/741 (34%), Gaps = 102/741 (13%)
Query: 3998 GPGMPAKPLQHFSSPGALGPTL---LLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTT 4054
GP P P + P A P+L L T + +PAV + P + +GGP +
Sbjct: 1254 GPATPP-PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT-----PPSPKGGPAT--SP 1305
Query: 4055 PESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGG 4114
P+ T P PS G P P+ P+ + PP + L
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGT----PPPKGAPTPPAVTPP------SPKGTPTLPATTPS 1355
Query: 4115 SHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQ-PMLERPMQNNTGPQ-- 4171
S G + SS E + P A PS G P++ P + P + T P
Sbjct: 1356 SKGGPTTPSSKEGPTPP--AATPS-----HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Query: 4172 --PPKPGP---VLQSGQGLPGVGIMPTVGQLRAQLQGVLAKN--------------PQLR 4212
PK P V + G P G + L+ A + P L
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP 1468
Query: 4213 HLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEP-GTQTSPLQGLLGCQP-QLGGFPGPQ 4270
++P ++ A +Q+ S + ++ P P G T P ++ P ++ P +
Sbjct: 1469 AVTPPSPKEPPA---PKQVATSSSPKKAPATPAPMGAPTLP--AVIPSSPKEVPATPSSR 1523
Query: 4271 TGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL 4330
P+ + P L AP AL P + P P+ P PK PS
Sbjct: 1524 RDPIAPTATLLSKKTPATL-APKEALIP-PAMTVPSPKKTPAIPT-PKEAPATPSSKEAS 1580
Query: 4331 PTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAET-QKP 4389
A P T+ G P P+ L PP SP+ P + P A T P
Sbjct: 1581 SPPAVTPSTYKGAPSPK--ELLIPPAVTSPS--------------PKEAPTPPAVTPPSP 1624
Query: 4390 EQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHL 4449
E+ P V +S P C +GA +V + + G P T+
Sbjct: 1625 EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGA-TVPQASKGLPAKKGPTALKE 1683
Query: 4450 LLAGPRSEAGHLLLQKLLRAKNVQLSTG---------RGSEGLRAEINGHIDSKLAGLEQ 4500
+L P E+ ++ + + S+ G + ++ + L +++
Sbjct: 1684 VLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQK 1743
Query: 4501 KLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSS--RKKLRKEDGVRASEALLKQLKQE 4558
T K+ A+ P P KAS L ++ K L K + S A +
Sbjct: 1744 DSSKTAKGKD--ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPV--S 1799
Query: 4559 LSLLPLTEPAITANFSLFAPFGSGCPVNGQSQ-LRGAFGSGALPTGP--DYYSQLLTKNN 4615
L L P P + F P G + S+ L A LP P + ++
Sbjct: 1800 LPLAPSPVPTLPPK-QQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSV 1858
Query: 4616 LSNPPTPPSSLPPTPPPSVQQKMV--NGVTPSEELGEHPKDAASARDSERALRDTSEVKS 4673
L N PTP S+ P P PS +Q + N + +E + +DS +A T++
Sbjct: 1859 LVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQA---TTQQAQ 1915
Query: 4674 LDLLAALPTPPHNQTEDVRME 4694
L A + P ++ + R E
Sbjct: 1916 LAAAAEIDEEPVSKAKQSRSE 1936
Score = 55.8 bits (133), Expect = 1e-06
Identities = 151/645 (23%), Positives = 221/645 (34%), Gaps = 105/645 (16%)
Query: 683 PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP--EEPQLCPRSEG 740
P EA+ P E P E + S+ + + P LP P PQ CP S
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 741 PHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQ 800
SP P ++ P E PQ+ P L PE P P GP +S
Sbjct: 62 NQASPFPSPSTIASTPLEVPF-PQSSSGTALP------LGTAPEAPTFLPNLIGPPIS-- 112
Query: 801 PEELHLSPQTEEPHLSPVPEE---------------------PCLSPQPEESHLSPQSEE 839
P L L+ P L P P L P ++
Sbjct: 113 PAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSV 172
Query: 840 PCLSPRPEESHLSPELEKPP--LSPRPEKPPEE-------PGQCPAP--------EELPL 882
LS S L K P + P P+ P P C P LP
Sbjct: 173 ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQ 232
Query: 883 FPPPGEPSL-SPLLGEPALSEPGEPPLSP--LPEELPLSPSGEPSLSPQLMP-------- 931
P ++ SP + + +S P +P L + P+SP SLS Q +P
Sbjct: 233 TTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKT 292
Query: 932 PDPLPPPLSPIITAA--APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEAN 989
P PP PI + AP S G ++ G + P S L+ P ++T
Sbjct: 293 AGPNTPPDFPISLGSHLAPLHQSSFGSVQ----LLGQTGP-SALSDPTVKTISVDHSSTG 347
Query: 990 CTDPEPVPPMILPPSPG-SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP-AL 1047
+ P ++PP P + V PA+ + P P CSP +L
Sbjct: 348 ASYPS--QRSVIPPLPSRNEVVPATVAAFPVVAPSVDK------GPSTISSITCSPSGSL 399
Query: 1048 PLSVPSPLSP-IGKVVGVSDEAELH-----EMETEKVSEPECPALEPSATSPLPSPMGDL 1101
++ LSP ++ S A H +M V P + P+ ++
Sbjct: 400 NVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEV 459
Query: 1102 SCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEEL- 1160
+ SP + S + E T+P + AP + EP T + + SP L DPE+L
Sbjct: 460 A-TCVSPPMSSGPISNI-EPTSPAALVMAPVAPKEP-STQVATTLRIPVSPPLPDPEDLK 516
Query: 1161 -APVTPMEVYPECKQTAGQGSPCEEQEEPRAPVA--------PTPPTLIKSDIVNEISNL 1211
P + + +P K Q P + P +P PT L+++ N S
Sbjct: 517 NLPSSVLVKFPTQKDL--QTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQ 574
Query: 1212 SQGDA-----SASFPGSEPLLGSPDPEG--GGSLSMELGVSTDVS 1249
S + S ++ LG P P G S++ LGV++ S
Sbjct: 575 STSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSAS 619
Score = 50.8 bits (120), Expect = 4e-05
Identities = 95/390 (24%), Positives = 126/390 (32%), Gaps = 65/390 (16%)
Query: 4620 PTPPSSLPPTPP--PSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVK----- 4672
PTPP+ PP+P P+ TP PK + +A + T
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068
Query: 4673 ---SLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGR 4729
+ L PTPP + S + PA++P S G A PH G+
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP-PHKGA-- 1125
Query: 4730 WEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVT---TWEKGKGSEVSV-- 4784
P P A+ P P G L P P T T KG +
Sbjct: 1126 ------------PTTPAATPP-----SPKGGLATPPPKGAPTTPAATPPSPKGGLATPPP 1168
Query: 4785 --MLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEV-----LFPESPARAGTEPKKGEAEG 4837
T AA + G + + + P + L SP A T P A
Sbjct: 1169 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP----AAT 1224
Query: 4838 PGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYN 4897
P + GL SP P P T S + PA PP
Sbjct: 1225 PPSPKGGLATPSPKGAP--------TTPAATPPSP--------KGGPATPPPKGAPTPPA 1268
Query: 4898 VSNLDVRQLSAPPPEEPSPPPSPLAP-SP-ASPPTEPLVELPTEPLAEPPVPSPLPLASS 4955
+ ++ A PP + +P P+ + P SP P T P PT P A PP P P
Sbjct: 1269 ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328
Query: 4956 PESARPKPRARPPE-EGEDSRPPRLKKWKG 4984
P+ A P PP +G + P KG
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358
Score = 48.1 bits (113), Expect = 2e-04
Identities = 186/833 (22%), Positives = 265/833 (31%), Gaps = 159/833 (19%)
Query: 4216 PQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQ 4275
PQ Q + L M L + A+ Q P P +P Q L Q FP P T
Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAST 76
Query: 4276 ELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQ 4335
L P PQ P G P P PP SP++
Sbjct: 77 PLEV-PFPQSSSGTALPLGTAPEAPTFLPNLIGPP-------------ISPAALALASPM 122
Query: 4336 LPPTHPGTPKPQGP--------------TLEPPPGRVSPAAAQLADT----LFSKGLGPW 4377
+ PT GTP P + PP SP + +A++ S + P
Sbjct: 123 IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPS 182
Query: 4378 DPPDNLAET------------QKPEQSSLVPGHLDQVNGQVVPEAS-QLSIKQEPREEP- 4423
+P NL + P S VP H V P AS Q + P+ P
Sbjct: 183 EPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHC------VTPMASIQSGVASLPQTTPT 236
Query: 4424 --CALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLL--QKLLRAKNVQLSTGRG 4479
A+ + VK + +P L L GP S L L Q L + Q + G
Sbjct: 237 TTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPN 296
Query: 4480 SEGLRAEINGHIDSKLAGLEQKLQGT--------PSNKED-----------------AAA 4514
+ + + S LA L Q G+ PS D +
Sbjct: 297 TP---PDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQ 353
Query: 4515 RKPLTPKPKR-------------VQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSL 4561
R + P P R V + D+ S+ + + A L SL
Sbjct: 354 RSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSL 413
Query: 4562 LPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPT 4621
+ + P T ++ L A + A PT + ++ S
Sbjct: 414 ILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSG--- 470
Query: 4622 PPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSL--DLLAA 4679
P S++ PT P ++ V PS ++ + S L D ++K+L +L
Sbjct: 471 PISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSP-----PLPDPEDLKNLPSSVLVK 525
Query: 4680 LPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESI-LGEEAPRFPHLGSGRWEQEDRALS 4738
PT QT +E S + + P + L + AP+ + + S
Sbjct: 526 FPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPK------NSPSFQSTSSS 579
Query: 4739 PVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVT--TWEKGKGSEVSVMLTVSAAAAKNL 4796
P IPL P A T +LG +P P + T G S SV+ T S A
Sbjct: 580 PEIPLSPEA-------TLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPD-- 630
Query: 4797 NGVMVAVAELLSMKIPNSYEVLFP-ESPARAGTEP--KKGEAEGPGGKEKGLEGK---SP 4850
+ LL + FP ES AG P KG + LEG +P
Sbjct: 631 -----SAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAP 685
Query: 4851 DTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESP-APEPPTQHSYTYNVSNLDVRQLSAP 4909
P + L L L+ S P P+ + ++ L +
Sbjct: 686 KNHP-------------VKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL------ 726
Query: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPV---PSPLPLASSPESA 4959
PE P PSP P +PP V+ + A PV P P S SA
Sbjct: 727 APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASA 779
Score = 39.7 bits (91), Expect = 0.084
Identities = 56/208 (26%), Positives = 76/208 (36%), Gaps = 19/208 (9%)
Query: 2371 PGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPS------DPFSRVPASPQSQSSSQSP 2424
PG T+ P T + P P LP S S P +P P S + Q P
Sbjct: 2 PGEATETV---PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPP-PCSPAPQQCP 57
Query: 2425 LTPRPLSAEAFCPSPV--TPRFQSPDPYSRPPSR-PQSRDPFAPLHKP----PRPQPPEV 2477
L+ ++ PS + TP + P P S + P P AP P P P +
Sbjct: 58 LSAANQASPFPSPSTIASTP-LEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAAL 116
Query: 2478 AFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFT 2537
A + +A T G A L + S PPN + SP + A + S + +
Sbjct: 117 ALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLS 176
Query: 2538 FPQAVGEPSLK-PPVPQPGLPPPHGINS 2564
P A EP VP +P P G S
Sbjct: 177 APIAPSEPKTNLNKVPSEVVPNPKGTPS 204
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 212 bits (540), Expect = 7e-54
Identities = 248/841 (29%), Positives = 321/841 (38%), Gaps = 165/841 (19%)
Query: 380 TPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMP 439
TP P + +G P+ P P + KP G ++ PQ+ P + P
Sbjct: 247 TPLSSPARSGPSARGTPRA-------PAHPS----QPKPKGLQALR-PPQVTPPRKDAAP 294
Query: 440 LLPPPEESPLSPPPEES----PTSPPPEASRLSP------PPEELP---ASPLPEALHLS 486
L P SPL+ P P PP A+ P PP P A P P A
Sbjct: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354
Query: 487 RPLEESPLSPPPE------ESPLSPPPESSPFSPLE--ESPLSPPEESPPSP-------- 530
+ L P +PP + P+ PP P++ S SP ++PPSP
Sbjct: 355 QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQA 414
Query: 531 --ALETP----------LSP-PPEASPLSP--PFEESPLSPP---PEELPTSPP------ 566
+L +P +SP +AS SP P P SPP P LP SPP
Sbjct: 415 TTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474
Query: 567 PEASRLSPPPEESPMSPPPEESPMSP-PPEASRLFPPFE-ESPLSPPPEESPLSPPPEAS 624
P S LS P P+ + SP P +S + PP E +S L+PP ++ P AS
Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT-----PPAS 529
Query: 625 RLSPPPEDSPMSPPPEESPMSPPPEVSRLS--PLPVVSRLSPPPEESPLSPPPEESPTS- 681
+PP E+ P PP S P L P P L PP SPL+ PP E+P+S
Sbjct: 530 LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP--SPLTTPPPETPSSI 587
Query: 682 --PPPEA-SRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
PPP+A L+ PP SPP PP ++LP ++P P P P L P +
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP-PASPPLSPLA 646
Query: 739 EGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLS 798
+P HL P P SP + P SP P P +SP A P +
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAP-FSP----------PASPPVSPSATPPSQA 695
Query: 799 PQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP 858
P P P L P P P +SP + P +P P L P
Sbjct: 696 P--------PSLAAPPLQVPPSPPASPP------MSPSATPPPQAP--------PPLAAP 733
Query: 859 PLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS 918
PL P PP P P+ PPP P PLL P L P PP S LP+S
Sbjct: 734 PLQV-PPSPPASPPMSPSAT-----PPPRVP---PLLAAPPLQVPPSPPAS-----LPMS 779
Query: 919 PSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEY------PFGAKGDSDPESP 972
P +P P PP PPL + +PPA P G+ + P P++P
Sbjct: 780 PLAKP---PPQAPPALATPPLQAL---PSPPASFP-GQAPFSPSASLPMSPLATPPPQAP 832
Query: 973 --LAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH 1030
LAAP+L+ P SPP P PP+PG + P L L P P
Sbjct: 833 PVLAAPLLQVPPSPPASPTLQAPR------RPPTPGPDTSVSGPRLTLALAPGPPP---- 882
Query: 1031 SLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSA 1090
P SP S S P L S S ++ G D + E A P+A
Sbjct: 883 --PPSRSPSSTLSGPDLAGHSSSATSTPEELRGY-DSGPEGGAAASPPPDAELAACHPAA 939
Query: 1091 TSPLPSP----MGDLSCPAPSPAP----ALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPG 1142
S P+P G P P P + D + E P APG+ +PG +PG
Sbjct: 940 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL-DPGPSPG 998
Query: 1143 S 1143
+
Sbjct: 999 T 999
Score = 207 bits (526), Expect = 3e-52
Identities = 238/830 (28%), Positives = 296/830 (35%), Gaps = 133/830 (16%)
Query: 441 LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALH-LSRPLEESPLSPPPE 499
LP P S PP E P AS S A P A L RP S S
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS---S 245
Query: 500 ESPLSPPPESSPFSPLEESPLSPPEESPPSP----ALETPLSPPP--EASPLSPPFEESP 553
+PLS P S P + +P +P S P P AL P PP +A+P P SP
Sbjct: 246 ATPLSSPARSGPSA--RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 554 LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE 613
L+ P SP +R PPP+ + +P P P SPP L P PL+PP
Sbjct: 304 LATP------SPSGTKARPVPPPDNAA-TPLPATLPPSPP-----LATPL---PLAPP-- 346
Query: 614 ESPLSPPPEASRLSPPPEDSPMSPPPEES--PMSPPPEVSRLSPLPVVSRLSPPPEESPL 671
SP S PP L PP P PP + PM PP + + P+ V L+ P ++P
Sbjct: 347 -SP-SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404
Query: 672 SP------PPEESPTSPPPEASR--LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLE-- 721
SP S SP +A+ L+ P + S PAS PP+ + PL
Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464
Query: 722 ESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCA 781
SP L P + P S + P L+ + LS P + P
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
Query: 782 VPEEPHLSPQAEG-PHLSPQPEELHLSPQTEEPHLSPVP-EEPCLSPQPEESHLSPQSEE 839
P +P E P L+P P + +P T PHL P PC P +P E
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTT-PHLETPPCPAPCPLQAPPSPLTTPPPET 583
Query: 840 PCL----SPRPEESHLSPELE---KPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLS 892
P P+ + SP L+ PPLSP PP+ P P PP P LS
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643
Query: 893 PL----------LGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPI 942
PL L L P PP SP P + P SP P +SP PP PP L
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPSATPPSQAPPSL--- 699
Query: 943 ITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILP 1002
AAPP P SP A+P + +PPP+A PP+ P
Sbjct: 700 ---AAPPL----------------QVPPSPPASPPMSPSATPPPQAP-------PPLAAP 733
Query: 1003 P---SPGSPVGP-----------------ASPILMEPLPPQCSPLLQHSLVPQNSPPSQC 1042
P P P P A P+ + P PP P+ + P +PP+
Sbjct: 734 PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793
Query: 1043 SPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLS 1102
+PP L P P S + + T P A P P L
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853
Query: 1103 CPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLAS--ELKG--SPVLLDPE 1158
P P P D T L APG P P ++P S S +L G S PE
Sbjct: 854 APRRPPTPGPDTSVSGPRLTLAL----APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 909
Query: 1159 EL------------APVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTP 1196
EL A P C A P AP AP P
Sbjct: 910 ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 959
Score = 156 bits (394), Expect = 6e-37
Identities = 173/592 (29%), Positives = 240/592 (40%), Gaps = 111/592 (18%)
Query: 366 TPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQ 425
TP S +PP + P+ P L A H+ + P PLQ
Sbjct: 525 TPPASLTTPPLE-NLPSLAPPPLQTA-SAPLTTPHLETPPCPAPCPLQA----------- 571
Query: 426 LEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTS---PPPEA--SRLSPPPEELPASPLP 480
PP SPL+ PP E+P+S PPP+A + SPP + LP+ PL
Sbjct: 572 ----------------PP---SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL- 611
Query: 481 EALHLSRPLEESPLSPPPEESP--LSPPPESSPFSPLEESPLSP-PEESPPSP------A 531
SPL+ PP ++P L+ PP +P SP PLSP SP +P
Sbjct: 612 -----------SPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660
Query: 532 LETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP--PEESP 589
L+ P SPPP + P+ PF P SPP T P L+ PP + P SPP P SP
Sbjct: 661 LQAPFSPPP-SPPVQAPF-SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718
Query: 590 -MSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP-MSPPPEESPMSPP 647
+PPP+A PP PL PP SP + PP + +PPP P ++ PP + P SPP
Sbjct: 719 SATPPPQAP---PPLAAPPLQVPP--SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773
Query: 648 PEVSRLSPLPVVSRLSPPPEESP-LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706
+ LP+ PPP+ P L+ PP ++ SPP +P SP++ P
Sbjct: 774 ------ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP---FSPSASLPMSPL 824
Query: 707 ASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAE 766
A+PPP+ + P+ +PLL +P P P + P RP P P L+
Sbjct: 825 ATPPPQ----APPVLAAPLLQVPPSPPASPTLQAPR---RPPTPGPDTSVSGPRLTLA-- 875
Query: 767 EPHLSPQPEEPCLCAVPEEPHLSPQA--EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCL 824
L+P P P P SP + GP L+ +P+ + S
Sbjct: 876 ---LAPGP--------PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 924
Query: 825 SPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFP 884
SP P+ + P P + P +P P P PG A ++
Sbjct: 925 SPPPDAELAACHPAAWSRGPAPPLA-----FRGAPGAPLPWPPATGPGS--ADGLCTIYE 977
Query: 885 PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
G S +P P +PG P + + + +G S SP+ LP
Sbjct: 978 TEGPESATP---APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 1026
Score = 116 bits (291), Expect = 5e-25
Identities = 196/784 (25%), Positives = 259/784 (33%), Gaps = 194/784 (24%)
Query: 2106 IPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPP 2165
+PP P L +P P A P SP+ P L T PP+ + P +P ++ PP
Sbjct: 331 LPPSP-PLATPLPLAPP-----SPSAPPSLQTLPSPPATPPSQAPPSMTTPP---MQAPP 381
Query: 2166 QVPAQVPSQDPFGL------APAYPL-------------------------EPRFPTAPP 2194
+ P Q P L AP PL PR A
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441
Query: 2195 TYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFL--------K 2246
T P P+ T P PP+ S P A P + +P +P P T P
Sbjct: 442 TSPSRPAST-PPDSPPLQAPLSLP-ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
Query: 2247 PRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGF 2306
P+ P L +L +P P + P L PP + LE + PS PP L
Sbjct: 500 PQAP-LSSLIMP--PLETQSSLAPPSLQTPPASLTTPPLE--------NLPSLAPPPLQT 548
Query: 2307 VDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAP-----S 2361
+P + HL P +AP +P + + P + PPA A P S
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608
Query: 2362 PPSHPDIFRPGSYTDPYAQPPLTPRPQPP--PPESCCALP-------------------- 2399
PP P P A PPL P PP PP S A P
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668
Query: 2400 ---PRSLPSDPFSRVPASPQSQSSSQSP---------LTPRPLSAEAFCPSPVTPRFQSP 2447
P P P + P SP + SQ+P + P P ++ PS TP Q+P
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS-ATPPPQAP 727
Query: 2448 DPYSRPPSR----PQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503
P + PP + P + P +P PP PP +A + + PA+LP P
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP------PASLPMSPL 781
Query: 2504 GELHAKVPSGQPPNFVRS------------PGTGAF----------VGTPSPMRFTFPQA 2541
AK P PP PG F + TP P P
Sbjct: 782 ----AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA---PPV 834
Query: 2542 VGEPSLKPPVPQPGLPPPHGINSHFGPGP--TLGKPQSTNYTVATGNFHPSGSPLGPSSG 2599
+ P L+ P P P PGP ++ P+ T PS SP SG
Sbjct: 835 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 894
Query: 2600 STGESYGLSPLRPPSVL------------PPPAPDGSLPYLSHGASQRSGITSPVEKRED 2647
+ S P L P PD L H A+ G P+ R
Sbjct: 895 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA-ACHPAAWSRGPAPPLAFRGA 953
Query: 2648 PG--------TGMGSS------------LATAELPGTQDPGMS----------GLSQTEL 2677
PG TG GS+ + PG DPG S G
Sbjct: 954 PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS 1013
Query: 2678 EKQRQRQRLREL--------LIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAF 2729
+ ++ RL EL +++ + R L E AA +G GP G+ G + A
Sbjct: 1014 SRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGG-GPGGAEGGGVTGGAR 1072
Query: 2730 EQLS 2733
LS
Sbjct: 1073 AALS 1076
Score = 111 bits (277), Expect = 2e-23
Identities = 178/685 (25%), Positives = 236/685 (34%), Gaps = 117/685 (17%)
Query: 626 LSPPPEDSPMSPPP-EESPMSPPPEVSRLSPLPVVSRL-----SPPPEESPLSPPPEES- 678
L+P P SP PPP + + + P+ R + PE +P + P +
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
Query: 679 -----PTSPPPEASRLSPPPEDSPTSPPPEDSP--------------------------- 706
P S PP + R P TSP P SP
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
Query: 707 --ASPPPEDSLMSLPLEESPLLPLPEEPQLC----PRSEGPHLS-PRPEEPHLSPRP--E 757
A+ P+ S +S P P P R+ G + PRP P PRP E
Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP-APSARPRPPTE 203
Query: 758 EPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP 817
P S + H + +P P P + LS L SP P
Sbjct: 204 GPRKSVSSASEHSTTEP-SPAARRRPSAGGGLQRPASRSLSSSATPLS-SPARSGPSARG 261
Query: 818 VPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAP 877
P P QP+ L PR + +P L PLS P P G P
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKD---AAPAL--GPLSSSPLATPSPSGTKARP 316
Query: 878 EELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSL----SPQLMPPD 933
PP + + +PL PA P P +PLP P SPS PSL SP PP
Sbjct: 317 ------VPPPDNAATPL---PATLPPSPPLATPLP-LAPPSPSAPPSLQTLPSPPATPPS 366
Query: 934 PLPPPLSPIITAAAPPALSPLGELEYPFGAKGDS--DPESPLAAPILETPI---SPPPEA 988
PP ++ APP+L + ++ P S P SPLA L+ SP +A
Sbjct: 367 QAPPSMT-TPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA 425
Query: 989 N----CTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSP 1044
P + PS + P SP L PL SP LQ SL P SP S
Sbjct: 426 THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS--- 482
Query: 1045 PALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCP 1104
PL++ PL + + S +A L + + E + PS +P P
Sbjct: 483 ---PLTI-HPLQALSSLASHSPQAPLSSLIMPPL-ETQSSLAPPSLQTP----------P 527
Query: 1105 APSPAPALDDFSGLGEDTAPLDGIDAPGSQP--EPGQTPGSLASELKGSPVLLDPEEL-- 1160
A P L++ L PL AP + P E P + SP+ P E
Sbjct: 528 ASLTTPPLENLPSLA--PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585
Query: 1161 -APVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASAS 1219
P + P QG P P +P+A PP L A S
Sbjct: 586 SIATPPPQAPPALASPPLQGLP----SPPLSPLATPPPQ------APPXLALPPLQAPPS 635
Query: 1220 FPGSEPL--LGSPDPEGGGSLSMEL 1242
P S PL L +P P+ +L++ L
Sbjct: 636 PPASPPLSPLATPSPQAPNALAVHL 660
Score = 102 bits (255), Expect = 8e-21
Identities = 233/938 (24%), Positives = 303/938 (32%), Gaps = 157/938 (16%)
Query: 2108 PQPGALGSP-PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGS-VPGPDSPGELFLKLPP 2165
P+P P PP P + S + + S +P AG + P S P
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 2166 QVPAQV-PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPG 2224
PA+ PS APA+P +P+ PP +P A P + SS P A
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
Query: 2225 EFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKA 2284
P P +TP P P P L P + + L SPP S+
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
Query: 2285 LEVKKEELGA----------------SSPS-YGPPNLGFVDSPSSGTHLGGLELK----- 2322
+ + A +SPS PP+ + S + T LG L+
Sbjct: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429
Query: 2323 ---TPDVFKAPLT--PRASQVEPQSPGLGL---RPQEPPPAQALAP--SPPSHPDIFRP- 2371
+P +A LT R + P SP L P PP +L+P SP S P P
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
Query: 2372 ---GSYTDPYAQPPLTPRPQPP--------PPESCCALPPRSLPSDPFSRVPA-SPQSQS 2419
S Q PL+ PP PP PP SL + P +P+ +P
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPS--LQTPPASLTTPPLENLPSLAPPPLQ 547
Query: 2420 SSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPR-PQPPEVA 2478
++ +PLT L CP+P P P P + PP S P PP PP
Sbjct: 548 TASAPLTTPHLETPP-CPAP-CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605
Query: 2479 FKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSP----- 2533
+ L+ P A P A A P PP+ SP + TPSP
Sbjct: 606 LPSPPLS---------PLATPPPQAPPXLALPPLQAPPSPPASPPLSP-LATPSPQAPNA 655
Query: 2534 MRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSP 2593
+ QA P PPV P PP S P+ P + P+ P
Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 715
Query: 2594 LGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMG 2653
+ PS +T PL P + PP+P S P+ P +
Sbjct: 716 MSPS--ATPPPQAPPPLAAPPLQVPPSPPAS---------------PPMSPSATPPPRVP 758
Query: 2654 SSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGA 2713
LA L P S L + L K + A
Sbjct: 759 PLLAAPPLQVPPSPPAS-LPMSPLAKPPPQ-------------------------APPAL 792
Query: 2714 VGPPGSWGAEPSSPAFEQLSRGQTPF--AGTQDKSSLVGLPPSK---LSGPILG-PGSFP 2767
PP A PS PA GQ PF + + S L PP L+ P+L P S P
Sbjct: 793 ATPP--LQALPSPPA---SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 847
Query: 2768 SDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAAT 2827
+ L P P TP D + V G + AP P P + L A ++
Sbjct: 848 ASPTLQAPRRPPTPGP-DTS----VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902
Query: 2828 SMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKG 2887
S GPE G A P A ++ P GPA P F
Sbjct: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS--RGPAPPLAF---------- 950
Query: 2888 LGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLH 2947
G G P P P P GL SA PAP +
Sbjct: 951 RGAPGAPLPW---------------PPATGPGSADGLCTIYETEGPESATPAPGALDP-G 994
Query: 2948 PTPHTKG--PTLPTGLELVNRPPSSTELGRPNPLALEA 2983
P+P T G G +R P LG AL+A
Sbjct: 995 PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQA 1032
Score = 95.5 bits (236), Expect = 1e-18
Identities = 242/1007 (24%), Positives = 320/1007 (31%), Gaps = 201/1007 (19%)
Query: 2087 QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPP 2146
+ K G AR A L P PG+ PPP + + G A+
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE-----R 61
Query: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYP-PYPSP--T 2203
AG + G P E + P A S++P PA R P A T P P SP
Sbjct: 62 AGGIGGATIP-ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
Query: 2204 GAPAQPPMLG----------------ASSRP-----GAGQPGEFHTTPPGTPRHQPS--- 2239
+P LG A+ P AG + PGTP +
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 2240 ----------TPDPFLKPRCP----------------SLDNLAVPESPGVGGG------- 2266
P P +PR P + + A P GGG
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 2267 ---KASEPLLSPPPFGESRKAL--------EVKKEELGA------------SSPSYGPPN 2303
++ PL SP G S + + K + L A ++P+ GP +
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 2304 LGFVDSPS-SGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP--PPAQALAP 2360
+ +PS SGT + PD PL P + L L P P PP+ P
Sbjct: 301 SSPLATPSPSGTK--ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP 358
Query: 2361 SPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSS 2420
SPP+ P P S T P Q P P Q PP P SL S P + P SP + SS
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAP--PSLQTIPPIQV----PHSLTS-PSLQAPPSPLALSS 411
Query: 2421 SQ------SPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPF-APLHKPPRP- 2472
Q SP S P SP SRP S P P APL P P
Sbjct: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSP---SRPASTPPDSPPLQAPLSLPASPP 468
Query: 2473 -----QPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAF 2527
P + H + P P L PP +S
Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI------MPPLETQSSLAPPS 522
Query: 2528 VGTPSPMRFTFPQAVGEPSLKPP----------VPQPGLPP-PHGINSHFGPGPTLGKPQ 2576
+ TP P T P PSL PP P PP P P P P
Sbjct: 523 LQTP-PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPP 581
Query: 2577 STNYTVATGNFHPSGSPLGPSSGSTGESYGL--SPLRPPSVLPPPAPDG-SLPYLSHGAS 2633
T ++AT P P + ++ GL PL P + PP AP +LP L A
Sbjct: 582 ETPSSIAT------PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQ--AP 633
Query: 2634 QRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQ 2693
+ P+ P ++LA L P S Q
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS---------PP 684
Query: 2694 QIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPP 2753
T + + AA PP + P SP+ + P A + +PP
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP-----LQVPP 739
Query: 2754 SKLSGPILGPGSFPS---DDRLSRPP---PPATPSSMDVNSRQLVGGSQAFYQRAPYPGS 2807
S + P + P + P L+ PP PP+ P+S+ ++ + P
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP----------LAKPPPQAP 789
Query: 2808 LPLQQQQQQLWQQQQATAATSMRFAMSARFPSTP---GPELGRQALGSPLAGI------S 2858
L Q A+ F+ SA P +P P L +PL + S
Sbjct: 790 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849
Query: 2859 TRLPGPGE-PVPGP----AGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVS--E 2911
L P P PGP +GP + L PG P P + P ++
Sbjct: 850 PTLQAPRRPPTPGPDTSVSGP--------RLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 901
Query: 2912 DPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLP 2958
PE LRG S PP EL + HP ++GP P
Sbjct: 902 SSATSTPEELRGYDSGPEGGAAASPPPDAEL-AACHPAAWSRGPAPP 947
Score = 89.0 bits (219), Expect = 1e-16
Identities = 202/837 (24%), Positives = 283/837 (33%), Gaps = 99/837 (11%)
Query: 2187 PRFPTAPPTYPPYPSPTGAPAQPPMLGASS----RPGAGQPGEFH--TTPPGTPRHQP-- 2238
P T P P P P PA +LGA+ +P A + G T P PR P
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 2239 ----STPDPFLKPRCPSLDNLAVPE---SPG-VGGGKASEPLLSPPPFGESRKALEVKKE 2290
S+ +P +P A P SPG V + P P G+ K L + E
Sbjct: 82 SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ--KGLRISAE 139
Query: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ 2350
E A + P + S + G TP +P R S+ GL
Sbjct: 140 ETVARGKATEAPKRSAL-SAGARRDTSGPTPGTP----SPAMARRSRAAGTEVGL----- 189
Query: 2351 EPPPAQALAPSPPSHPDIFRPGSYTD-PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFS 2409
P PA + P PP+ S ++ +P R +P RSL S S
Sbjct: 190 -PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS---S 245
Query: 2410 RVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKP 2469
P S ++S + TPR A A P Q+ P P R + PL
Sbjct: 246 ATPLSSPARSGPSARGTPR---APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
Query: 2470 PRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGP--AGELHAKVPS-GQPPNFVRSPGTGA 2526
P P KA + A PA LP P A L PS PP+ P A
Sbjct: 303 PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362
Query: 2527 FVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGN 2586
+ +P T P PSL+ P + PH + S P+L P S +A +
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPP---IQVPHSLTS-----PSLQAPPSP---LALSS 411
Query: 2587 FHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRE 2646
+ S P+ +T +SP + + L P+ S P + +P+
Sbjct: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP------PDSPPLQAPLSLPA 465
Query: 2647 DPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKET 2706
P + +SL+ A P + + L Q LI ++ +
Sbjct: 466 SPP--LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 2707 AAAAAGAVGPPGSWGAEPSSPAFEQLSRG-QTPFAGTQDKSSLVGL--PPSKLSGPILGP 2763
A PP + P + S TP T + L PPS L+ P P
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP---P 580
Query: 2764 GSFPSDDRLSRPPPPATPSSMD-----VNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLW 2818
PS ++ PPP A P+ + S L + Q P PLQ
Sbjct: 581 PETPSS--IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638
Query: 2819 QQQQATAATSMRFAMSA------RFPSTPGPELGRQALGSPLAG--ISTRLPGPGEPVPG 2870
+ AT A +A + P +P P QA SP A +S P + P
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698
Query: 2871 PAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLP 2930
A P + + P TP P Q PP P++ P ++ P + P
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATP-PPQAPP------PLAAPPLQVPP------SPPASP 745
Query: 2931 PQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLP 2987
P PSA P P + L P P+ P L + + L +P P A A P
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM-------SPLAKPPPQAPPALATP 795
Score = 80.5 bits (197), Expect = 4e-14
Identities = 216/956 (22%), Positives = 312/956 (32%), Gaps = 159/956 (16%)
Query: 4037 ATEGPSTHQGGPL-AIGTTPESMATEP-----GEVKPSLSGDSQLLLVQPQPQPQPSSLQ 4090
AT S + GP + GT+ + A+ P GE P S P P +S
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP----GPVSSPGRASGT 123
Query: 4091 LQP-PLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMT 4149
+P PL GQ+ ++S T G + S+ A A+ S G PG+ +
Sbjct: 124 TRPGPL---GQKGLRISAEETVARGKATEAPKRSALSAG------ARRDTS-GPTPGTPS 173
Query: 4150 QNLLGPQQPM-----LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGV 4204
+ + L RP + P+PP GP P+ R G
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPS-ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
Query: 4205 LAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLG 4264
+ P R LS A + + + R TP +Q P +GL +P
Sbjct: 233 GLQRPASRSLSSS------ATPLSSPARSGPSARGTPRAPAHPSQPKP-KGLQALRPPQV 285
Query: 4265 GFP----GPQTGPLQELG-AGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKR 4319
P P GPL A P P G P PP + P+ + P+PP ++P
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345
Query: 4320 PSQLPSPSSQ-LPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWD 4378
PS PS Q LP+ PP+ P P ++ PP + Q+ +L S L
Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQ-APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA-- 402
Query: 4379 PPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGE 4438
PP LA + +SL G +A+ + PR+ +L + S R A+
Sbjct: 403 PPSPLALSSLQATTSL---------GSPTLQATHSFLTMSPRQTQASLTSPS--RPASTP 451
Query: 4439 PIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGL 4498
P P L P S LQ L LS+ L+A + S A L
Sbjct: 452 PDSPP-------LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL 504
Query: 4499 EQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQE 4558
+ + A TP + L S L +
Sbjct: 505 SSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS-----------------LAPPPLQ 547
Query: 4559 LSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSN 4618
+ PLT P + P + CP+ P P LT +
Sbjct: 548 TASAPLTTPHLET-----PPCPAPCPLQA-------------PPSP------LT----TP 579
Query: 4619 PPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLA 4678
PP PSS+ TPPP + + P + L P L+
Sbjct: 580 PPETPSSI-ATPPPQAPPALAS--PPLQGLPSPP------------------------LS 612
Query: 4679 ALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALS 4738
L TPP + + + SP PAS P S L +P+ P+ + Q +
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSP----PASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668
Query: 4739 PVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNG 4798
P P+ S P P P + P L + S ++ SA
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728
Query: 4799 VMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLK 4858
+ A +++P S P SP+ P + P + P L
Sbjct: 729 PLAAP----PLQVPPSPPASPPMSPSATPPPRVPPLLAAP-------PLQVPPSPPASLP 777
Query: 4859 QFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPP 4918
P L L SP P Q ++ + S L + L+ PPP+ P
Sbjct: 778 MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS-LPMSPLATPPPQAPPVLA 836
Query: 4919 SPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPE------SARPKPRARPP 4968
+PL P SPP P ++ P PP P P S P P P +R P
Sbjct: 837 APLLQVPPSPPASPTLQAP----RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
Score = 80.1 bits (196), Expect = 6e-14
Identities = 213/921 (23%), Positives = 301/921 (32%), Gaps = 195/921 (21%)
Query: 4115 SHGQLGSGSSSEASSVPHLLAQPSVSLGDQP----GSMTQNLLGPQQPMLERPMQNNT-G 4169
S G + S + ++ P L Q + + + G T+ P++ L + +T G
Sbjct: 110 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE---APKRSALSAGARRDTSG 166
Query: 4170 PQPPKPGPVLQSGQGLPG--VGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLM 4227
P P P P + G VG+ R + + P+ S + +
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP---TEGPRKSVSSASEHSTTEPSPA 223
Query: 4228 QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQG-- 4285
R+ + Q P + + +PL P G P P Q P+P+G
Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-----PKPKGLQ 278
Query: 4286 --------PPRLPAPP--GALSTGPVLGP------VHPTPPPSSPQEPKRPSQLPSPSSQ 4329
PPR A P G LS+ P+ P P PPP + P P+ LP PS
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL-PATLP-PSPP 336
Query: 4330 LPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389
L T L P P P P+L+ P SP A + S P P +L +T P
Sbjct: 337 LATPLPLAPPSPSAP----PSLQTLP---SPPATPPSQAPPSMTTPPMQAPPSL-QTIPP 388
Query: 4390 EQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHL 4449
Q VP L + Q P LS Q +LG+ +++ ++
Sbjct: 389 IQ---VPHSLTSPSLQAPPSPLALSSLQATT----SLGSPTLQ------------ATHSF 429
Query: 4450 LLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNK 4509
L PR Q L + + ST S L+A ++ L T +
Sbjct: 430 LTMSPRQT------QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQ--------TSLSP 475
Query: 4510 EDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAI 4569
+ PLT P + A L S + S ++ L+ + SL P P++
Sbjct: 476 AVSPLSSPLTIHPLQ---ALSSLASHSPQ------APLSSLIMPPLETQSSLAP---PSL 523
Query: 4570 -TANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTP---PSS 4625
T SL P P L+ A S LT +L PP P P
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTA-------------SAPLTTPHLETPPCPAPCPLQ 570
Query: 4626 LPP----TPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALP 4681
PP TPPP TPS + P A A S S L+ L
Sbjct: 571 APPSPLTTPPPE---------TPSS-IATPPPQAPPALASPPLQGLPSPP-----LSPLA 615
Query: 4682 TPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVI 4741
TPP + + + SP PAS P S L +P+ P+ + Q + P
Sbjct: 616 TPPPQAPPXLALPPLQAPPSP----PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671
Query: 4742 PLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMV 4801
P+ S P P P + P L + S ++ SA
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP-------- 723
Query: 4802 AVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFD 4861
P++P P + P P P L
Sbjct: 724 ------------------PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 4862 AVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEP----SPP 4917
+P P PP ++L + L+ PPP+ P +PP
Sbjct: 766 LQVP--------------------PSPP---------ASLPMSPLAKPPPQAPPALATPP 796
Query: 4918 ----PSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGED 4973
PSP A P P P LP PLA PP +P LA+ P P A P +
Sbjct: 797 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA-P 855
Query: 4974 SRPPRLKKWKGVRWKRLRLLL 4994
RPP V RL L L
Sbjct: 856 RRPPTPGPDTSVSGPRLTLAL 876
Score = 77.0 bits (188), Expect = 5e-13
Identities = 178/773 (23%), Positives = 244/773 (31%), Gaps = 116/773 (15%)
Query: 4281 PRPQGPPRLPAP--PGALSTGPVLGPVHPTP-------------PPSSPQEPKRPSQLPS 4325
PRP G PR P P P AL G V P P S+P+ P++
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG--PTRSAG 84
Query: 4326 PSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADT----LFSKGLGPWDPPD 4381
SS+ P A PP G + P PG VS T L KGL +
Sbjct: 85 TSSRNP--ASRPPAS-GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI-SAEE 140
Query: 4382 NLAE---TQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGE 4438
+A T+ P++S+L G +G P ++ + R A G + G
Sbjct: 141 TVARGKATEAPKRSALSAGARRDTSGPT-PGTPSPAMARRSR----AAGTEV------GL 189
Query: 4439 PIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGL 4498
P AP GPR GL+ + + S L
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 4499 EQKLQGTPSNK-EDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQ 4557
+ PS + A P PKPK +Q V+ +K A+ AL
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK-------DAAPAL-----G 297
Query: 4558 ELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGA-----LPTGPDYYSQLLT 4612
LS PL P+ + + P P N + L LP P S +
Sbjct: 298 PLSSSPLATPSPSGTKARPVP----PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS 353
Query: 4613 KNNLSNPP-TPPSSLPP--TPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTS 4669
L +PP TPPS PP T PP + + P + + A S AL
Sbjct: 354 LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ 413
Query: 4670 EVKSL---------DLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPES--ILGEE 4718
SL L P + DSP P S P S +
Sbjct: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL 473
Query: 4719 APRFPHLGSGRWEQEDRALSPVIPLIPRASIP--VFPDTKPYGALG----LEVPGKLPVT 4772
+P L S +ALS + P+A + + P + +L P L
Sbjct: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
Query: 4773 TWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKK 4832
E + T SA A P+ PE+P+ T P +
Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 4833 GEAEGPGGKEKGLEG----------------------KSPDTGPDWLKQFDAVLPGYTLK 4870
+GL ++P + P P
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653
Query: 4871 SQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPT 4930
+ L + L SP P PP Q ++ S PP + PPS PS A+PP
Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPAS---------PPVSPSATPPSQAPPSLAAPPL 704
Query: 4931 E----PLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRL 4979
+ P P P A PP +P PLA+ P P P A PP + PPR+
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Score = 75.5 bits (184), Expect = 1e-12
Identities = 173/701 (24%), Positives = 238/701 (33%), Gaps = 132/701 (18%)
Query: 4325 SPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA 4384
+P+++ P L P PG+P+P PPP V+PAA ++ + G P LA
Sbjct: 16 TPAARAP--GLLTPRPPGSPRP------PPP--VTPAALRVLGAAGAVGRKP------LA 59
Query: 4385 ETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALG----AQSVKREANGEPI 4440
E + +P + P S + + P P A G A K + G P+
Sbjct: 60 ERAGGIGGATIPESAPRAG----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG-PV 114
Query: 4441 GAPGTSNHLLLAGPRSEAGHLLL--QKLLRAKNVQLSTGRG-SEGLRAEINGHID----- 4492
+PG ++ GP + G + + + R K + S G R + +G
Sbjct: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
Query: 4493 -----SKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLV---SSRKKLRKEDG 4544
S+ AG E G P A R P K V AS+ S + R G
Sbjct: 175 AMARRSRAAGTE---VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 4545 VRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQ-LRGAFGSGALPTG 4603
+ L S PL+ PA + + P P + + L+ P
Sbjct: 232 GGLQRPASRSLSS--SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289
Query: 4604 PDYYSQL--LTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDS 4661
D L L+ + L+ P + P PPP N TP P A
Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARPVPPPD------NAATPLP--ATLPPSPPLATPL 341
Query: 4662 ERALRDTSEVKSLDLLAALP-TPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGE--E 4718
A S SL L + P TPP + + S +I P P S+ +
Sbjct: 342 PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401
Query: 4719 APRFP----------HLGSGRWEQEDRALSPVIPLIPR------------ASIPVFPDTK 4756
AP P LGS + A + + PR AS P PD+
Sbjct: 402 APPSPLALSSLQATTSLGSPTLQ----ATHSFLTMSPRQTQASLTSPSRPASTP--PDSP 455
Query: 4757 PYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIP--NS 4814
P A L +P P+ T S +S LT+ A + A L S+ +P +
Sbjct: 456 PLQA-PLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514
Query: 4815 YEVLFPES----PARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLK 4870
L P S PA T P + P P P T
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLE---------------NLPSLAPP---------PLQTAS 550
Query: 4871 SQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPS---PPPSPLAPSPAS 4927
+ L L PAP P L+ PPPE PS PP P+ AS
Sbjct: 551 APLTTPHLETPPCPAPCP----------LQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600
Query: 4928 PPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968
PP + L P PLA PP +P LA P A P P A PP
Sbjct: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP 641
Score = 74.7 bits (182), Expect = 2e-12
Identities = 124/506 (24%), Positives = 166/506 (32%), Gaps = 56/506 (11%)
Query: 3971 QQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKP---------LQHFSSPGALGPTLLL 4021
+Q Q L + SR +P Q L +PA P + SSP + P L
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLS--LPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492
Query: 4022 TGKEQNTVDPAVSSEATEGPSTHQG-GPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQP 4080
+ ++ +SS T P ++ T P S+ T P E PSL+ P
Sbjct: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552
Query: 4081 QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVS 4140
P + PP P Q S L T + S ++ P LA P +
Sbjct: 553 LTTPHLET----PPCPAPCPLQAPPSPLTTPPP----ETPSSIATPPPQAPPALASPPLQ 604
Query: 4141 LGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQ 4200
P P P+ P Q P P LQ+ P + + Q
Sbjct: 605 GLPSP---------PLSPLATPPPQ----APPXLALPPLQAPPSPPASPPLSPLATPSPQ 651
Query: 4201 LQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQ 4260
LA + SP +QA + TPP Q P + +P
Sbjct: 652 APNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAP-------- 702
Query: 4261 PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRP 4320
L P P P A P PQ PP L APP + P P P PS+ P+ P
Sbjct: 703 -PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP---PASPPMSPSATPPPRVP 758
Query: 4321 SQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
L +P Q+P P + P +P + P PP P A + G P+ P
Sbjct: 759 PLLAAPPLQVPPSP--PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
Query: 4381 DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEP------CALGAQSVKRE 4434
+L + P L QV P Q PR P G +
Sbjct: 817 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 876
Query: 4435 ANGEPIGAPGTSNHLLLAGPRSEAGH 4460
A G P P S L+GP AGH
Sbjct: 877 APGPP-PPPSRSPSSTLSGP-DLAGH 900
Score = 62.0 bits (149), Expect = 2e-08
Identities = 152/596 (25%), Positives = 201/596 (33%), Gaps = 80/596 (13%)
Query: 1865 TPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLGCGTPGLEGSRTPLQRP 1924
+P LSS L + L + S Q ++ E P L+ L P
Sbjct: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
Query: 1925 FLQGGLPLGNLPSSSP--MDSYPGLCQSPFLDSRERGGFFSPEP---GEPDSPWTGSGGT 1979
PL NLPS +P + + +P L++ P P P SP T
Sbjct: 534 ------PLENLPSLAPPPLQTASAPLTTPHLETPP-----CPAPCPLQAPPSPLTTPPPE 582
Query: 1980 TPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWS 2039
TPS+ TP + S + L L L+T P + P L+ P
Sbjct: 583 TPSSIATPPPQAPPALASPPLQGLP----SPPLSPLATPPPQAPPXLALPPLQA--PPSP 636
Query: 2040 SRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDR 2099
+ L P A A + + + VQ +
Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696
Query: 2100 PALH---LRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSP 2156
P+L L++PP P A P+A P P P L +A PP+ P SP
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATP-----PPQAPPPL--AAPPLQVPPSPPASPPMSP 749
Query: 2157 GELFLKLPPQV-------PAQVPSQDPFGLAPAYPLEPRFPTAPPTY--PP---YPSPTG 2204
PP+V P QVP P L P PL P APP PP PSP
Sbjct: 750 S---ATPPPRVPPLLAAPPLQVPPSPPASL-PMSPLAKPPPQAPPALATPPLQALPSPPA 805
Query: 2205 A-PAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLK-----PRCPSLDNLAVP 2258
+ P Q P P A P TPP P+ P P L+ P P+L P
Sbjct: 806 SFPGQAPF-----SPSASLPMSPLATPP--PQAPPVLAAPLLQVPPSPPASPTLQAPRRP 858
Query: 2259 ESPG----VGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDS-PSSG 2313
+PG V G + + L PP SR SS GP G S S+
Sbjct: 859 PTPGPDTSVSGPRLTLALAPGPPPPPSR----------SPSSTLSGPDLAGHSSSATSTP 908
Query: 2314 THLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPP-SHPDIFRPG 2372
L G + P+ A P +++ P R PP A AP P P PG
Sbjct: 909 EELRGYD-SGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 967
Query: 2373 SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR 2428
S D T P+ P + AL P P + A + +SS+SP R
Sbjct: 968 S-ADGLCTIYETEGPESATP-APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 1021
Score = 60.1 bits (144), Expect = 6e-08
Identities = 122/504 (24%), Positives = 159/504 (31%), Gaps = 103/504 (20%)
Query: 3983 TLLSPQQQQQQQVALGPGMPAKPLQHFSSP----GALGPTLLLTGKEQNTVDPAVSSEAT 4038
+L+ P + Q +A P + P + P +L P L T T P + +
Sbjct: 506 SLIMPPLETQSSLA-PPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT-PHLETPPC 563
Query: 4039 EGPSTHQGGPLAIGT----TPESMATEPGEVKPSLSGDSQLLLVQPQ------PQPQPSS 4088
P Q P + T TP S+AT P + P+L+ L P P PQ
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623
Query: 4089 LQLQPPLRLPGQQQQQVSLLHTAGGGSHG------QLGSGSSSEASSVPHLL-----AQP 4137
PPL+ P L A L S S P A P
Sbjct: 624 XLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Query: 4138 SVSLGDQPGSMTQNLLG------PQQPMLERPMQNNTGPQPPKPGPV----LQSGQGLPG 4187
VS P S L P P PM + P P P P+ LQ P
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
Query: 4188 VGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPG 4247
M ++ +LA P SP + L + PP P
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA------------KPPPQAPPA 791
Query: 4248 TQTSPLQGLLGCQPQLGG---FPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGP 4304
T PLQ L G F + P+ L A P PQ PP L AP + P P
Sbjct: 792 LATPPLQALPSPPASFPGQAPFSPSASLPMSPL-ATPPPQAPPVLAAPLLQVPPSPPASP 850
Query: 4305 V------HPTPPPSS------------PQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPK- 4345
PTP P + P P PS+ PS + P A + TP+
Sbjct: 851 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 910
Query: 4346 -------PQGPTLEPPPGRVSPAAAQLADTLFSKGLGP-------------WDPPDN--- 4382
P+G PP AA A +S+G P W P
Sbjct: 911 LRGYDSGPEGGAAASPPPDAELAACHPA--AWSRGPAPPLAFRGAPGAPLPWPPATGPGS 968
Query: 4383 ------LAETQKPEQSSLVPGHLD 4400
+ ET+ PE ++ PG LD
Sbjct: 969 ADGLCTIYETEGPESATPAPGALD 992
Score = 39.7 bits (91), Expect = 0.084
Identities = 78/327 (23%), Positives = 101/327 (30%), Gaps = 47/327 (14%)
Query: 3999 PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPES- 4057
P + A PLQ SP A P P + PS P++ TP
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756
Query: 4058 ----MATEPGEVKPSLSGDSQLL-LVQPQPQPQPS----SLQL--QPPLRLPGQQQQQVS 4106
+A P +V PS + L +P PQ P+ LQ PP PGQ S
Sbjct: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
Query: 4107 LLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQN 4166
S ++ P +LA P + + P P P L+ P +
Sbjct: 817 ASLPM---------SPLATPPPQAPPVLAAPLLQVPPSP---------PASPTLQAPRR- 857
Query: 4167 NTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALL 4226
PP PGP + + P ++ P L S + L
Sbjct: 858 -----PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912
Query: 4227 MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLG--GFPG------PQTGPLQELG 4278
+ A PP E P G P L G PG P TGP G
Sbjct: 913 GYDSGPEGGAAASPPPDAELAA-CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971
Query: 4279 AGP--RPQGPPRLPAPPGALSTGPVLG 4303
+GP PGAL GP G
Sbjct: 972 LCTIYETEGPESATPAPGALDPGPSPG 998
Score = 34.3 bits (77), Expect = 3.5
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 14/87 (16%)
Query: 4908 APPPEEPSPPPSPLAPSPASPPTEPLV----ELPTEPLAE-------PPVPSPLPLASSP 4956
AP P PP SP P P +P ++ + +PLAE +P P A
Sbjct: 21 APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80
Query: 4957 ESA---RPKPRARPPEEGEDSRPPRLK 4980
SA P +RPP G R P K
Sbjct: 81 RSAGTSSRNPASRPPASGRGERAPPAK 107
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 185 bits (470), Expect = 9e-46
Identities = 103/291 (35%), Positives = 158/291 (54%), Gaps = 17/291 (5%)
Query: 5259 SPQAVWNRIIEPVAAMRKEADMLRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYL 5318
S + W +IE V R A + L + G L G+ AV+ +AE LPG + CQ+Y
Sbjct: 2430 SLEGAWRTLIEKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYK 2489
Query: 5319 FRYGRHPLMELPLMINPTGCARSEPKILTHYKRPHTLNSTSMSKAYQSTFTGETNTPYSK 5378
FRY + + +NP G AR+E Y R T + + + +
Sbjct: 2490 FRYHQQGEGQEEPPLNPHGAARAEV-----YLRKCTFDMFNFLASQHRVLPEGATCDEEE 2544
Query: 5379 QFVHSKSSQ------------YRRLRTEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEY 5426
V +S++ +R L+ K V + RS I G GL+ ++++ MVIEY
Sbjct: 2545 DEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEY 2604
Query: 5427 IGTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVV 5486
G +IR+ + ++REK Y+ + G YMFR+++ V+DAT+ G AR+INHSC PNC + V+
Sbjct: 2605 SGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVI 2664
Query: 5487 TFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN 5537
+ + I+I + RRI +GEELTYDY+F ED +K+PC+CGA CR+++N
Sbjct: 2665 HVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN 2715
Score = 129 bits (324), Expect = 8e-29
Identities = 71/211 (33%), Positives = 109/211 (51%), Gaps = 9/211 (4%)
Query: 5028 DMRRCCFCHEEGDGATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRG 5087
D R+C C + GD + RLL + + W H+NCA+WS EV+E G+L NV A+ RG
Sbjct: 1577 DPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARG 1636
Query: 5088 LLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPMHK--IKGPCEQE 5145
+C LC + GAT C C + +HF CA + C+F DK + C H + G
Sbjct: 1637 RQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIVN 1696
Query: 5146 LSSFAVFRRVYIERDEVKQIASIIQ--RGERLHMFRVGGLVFHAIGQLLPHQMADFHSAT 5203
F V RRVY++ + + + + +++ +G + ++G L ++D
Sbjct: 1697 PDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVL-IGSIRIDSLGTL--SDLSDCEG-- 1751
Query: 5204 ALYPVGYEATRIYWSLRTNNRRCCYRCSIGE 5234
L+P+GY+ +R+YWS RRC YRC I E
Sbjct: 1752 RLFPIGYQCSRLYWSTVDARRRCWYRCRILE 1782
Score = 125 bits (313), Expect = 2e-27
Identities = 137/457 (29%), Positives = 183/457 (40%), Gaps = 66/457 (14%)
Query: 490 EESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF 549
EE E+ + E P + EE+ L PP +PP+P+ PL PPP SP PP
Sbjct: 371 EEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPL-PPPSTSP--PP- 426
Query: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP-PEESPMSPPPEASRLFPPFEESPL 608
PL PPP PPP +SPPP SP PP EE SPPP + P
Sbjct: 427 ---PLCPPP------PPP----VSPPPLPSPPPPPAQEEQEESPPP----VVPATCSRKR 469
Query: 609 SPPPEESPLSPPPEASRLSP----PPEDSPMSP---PPEESPMSPPPEVSRLSP-----L 656
PP EA+R P PP +P + PPE+SP P + L +
Sbjct: 470 GRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIM 529
Query: 657 PVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM 716
PVVS S ++P E+ P P E S + PP + P E +P PP
Sbjct: 530 PVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPR---- 585
Query: 717 SLPLEESPLLPLPE-------EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL-SPQAEEP 768
P S +PLPE EP S L P P P P P P + + P
Sbjct: 586 -APTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRP 644
Query: 769 HLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQP 828
L P+ P E HL + L+P P +P+ E P P EP
Sbjct: 645 LLLRAPQ-----FTPSEAHL--KIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVG 697
Query: 829 EESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPE--EPGQCPAPEELPLFPPP 886
+HLS P ++ P ++ +SP P LS P+ + +P Q + LP PP
Sbjct: 698 RTNHLSLPRFAPVVT-TPVKAEVSPH-GAPALSNGPQTQAQLLQPLQALQTQLLPQALPP 755
Query: 887 GEPSLS--------PLLGEPALSEPGEPPLSPLPEEL 915
+P L P L + ++ G PLS + E++
Sbjct: 756 PQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKM 792
Score = 120 bits (302), Expect = 3e-26
Identities = 122/392 (31%), Positives = 165/392 (42%), Gaps = 67/392 (17%)
Query: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS 477
PL P L P P L PP P+SPPP SP PP + + PP +PA+
Sbjct: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPAT 464
Query: 478 -----PLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESP----- 527
P R E+ + P SP +P P ++ P E+SP P+ +
Sbjct: 465 CSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNI 524
Query: 528 -----------PSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP-PEASRLSPP 575
S ++TP E P P E SP+ PP + TSPP P+ P
Sbjct: 525 RQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPP--ITTSPPVPQEPAPVPS 582
Query: 576 PEESPMSPPPEESPMSPPPEASRLF---PPFEESPLSPPPEESPLSPPPEASRLSPPPED 632
P P +P P +P+ P PE R P F + L+ L PPP A PPP
Sbjct: 583 P---PRAPTPPSTPV-PLPEKRRSILREPTFRWTSLT-----RELPPPPPA----PPPPP 629
Query: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692
+P SPPP + S P + R +P S ES L+PPP +P +P PE PP
Sbjct: 630 AP-SPPPAPATSSRRPLLLR-APQFTPSEAHLKIYESVLTPPPLGAPEAPEPE-----PP 682
Query: 693 PEDSPTSPPPEDSPASPPP----EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLS--PR 746
P D DSPA P P + +SLP +P++ P + ++ P P LS P+
Sbjct: 683 PAD--------DSPAEPEPRAVGRTNHLSLP-RFAPVVTTPVKAEVSPHG-APALSNGPQ 732
Query: 747 PEEPHLSP-RPEEPHLSPQA---EEPHLSPQP 774
+ L P + + L PQA +P L P P
Sbjct: 733 TQAQLLQPLQALQTQLLPQALPPPQPQLQPPP 764
Score = 107 bits (266), Expect = 4e-22
Identities = 155/558 (27%), Positives = 206/558 (36%), Gaps = 116/558 (20%)
Query: 577 EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP-PEESPLSPPPEASRLSPPPEDSPM 635
EE EE + E ++L PP PL+PP P P PPP S PPP P+
Sbjct: 379 EEKEERAVAEEMMPAAEKEEAKLPPP----PLTPPAPSPPPPLPPPSTS---PPP---PL 428
Query: 636 SPPPEESPMSPPPEVSRLSPLPVVSRLSPPP----EESPLSPPPE----------ESPTS 681
PPP P+SPPP LP SPPP EE SPPP P +
Sbjct: 429 CPPPPP-PVSPPP-------LP-----SPPPPPAQEEQEESPPPVVPATCSRKRGRPPLT 475
Query: 682 PPPEASRLSPPPEDSPTSPP-PEDSPASP-PPEDSLMSLPLEESPLLPLPE--EPQLCPR 737
P A R + TSPP P S A+ PPEDS P + L + + P + R
Sbjct: 476 PSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSAR 535
Query: 738 SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLS--PQPEEPCLCAVPEEPHLSPQAEGP 795
S +PR P+P + +SP P + P P+EP VP P P
Sbjct: 536 SSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPA--PVPSPPRAPTPPSTP 593
Query: 796 HLSPQPEELHLSPQT-----------EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCL-- 842
P+ L T P P P P P P S S P L
Sbjct: 594 VPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATS-----SRRPLLLR 648
Query: 843 SPR--PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL 900
+P+ P E+HL ++ + L+P P PE P PE P P EP + L
Sbjct: 649 APQFTPSEAHL--KIYESVLTPPPLGAPE----APEPEPPPADDSPAEPEPRAVGRTNHL 702
Query: 901 SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYP 960
S P P+ P + +SP G P+LS L PL + T P AL P
Sbjct: 703 SLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPP------- 755
Query: 961 FGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPL 1020
P+ L PPP P +PP + + + + +
Sbjct: 756 --------PQPQL---------QPPPS----------PQQMPPLEKARIAGVGSLPLSGV 788
Query: 1021 PPQCSPLLQHS---LVPQNSPPSQCSPPALPLSVPSPLSPI-GKVVGVSD------EAEL 1070
+ LL+ + L + Q ++PLS + + G V +SD E E
Sbjct: 789 EEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDES 848
Query: 1071 HEMETEKVSEPECPALEP 1088
E + E+ S PE P P
Sbjct: 849 VEAKRERPSGPESPVQGP 866
Score = 104 bits (259), Expect = 3e-21
Identities = 68/210 (32%), Positives = 93/210 (44%), Gaps = 31/210 (14%)
Query: 1379 MCVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKG-WRCVECIVCEVCGQAS 1437
+C++C S G L+ C C +HP+C+ + W C C C VCG+
Sbjct: 1203 VCLLCASKGLH---ELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKG 1259
Query: 1438 DPSRLLL-CDDCDISYHTYCLDPPL---LTVPKGGWKCKWCVSCMQCGAASPG--FHCEW 1491
S+ LL C+ C +YH CL P T + W C CV C CGA +PG + EW
Sbjct: 1260 RGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGA-TPGKNWDVEW 1318
Query: 1492 QNSYTHCGPCASLVT----CPICHAPYVEEDL---LIQCRHCERWMHAGCESLFTEDDVE 1544
Y+ C C L CPIC Y + D ++QC C+ W+HA CE L
Sbjct: 1319 SGDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGL------- 1371
Query: 1545 QAADEGFDCVSCQP----YVVKPVAPVAPP 1570
+DE ++ +S P Y P A A P
Sbjct: 1372 --SDEDYEILSGLPDSVLYTCGPCAGAAQP 1399
Score = 83.6 bits (205), Expect = 5e-15
Identities = 51/149 (34%), Positives = 66/149 (44%), Gaps = 15/149 (10%)
Query: 229 CAVCEGPGELCDLFFCTSCGHHYHGACLDTALTA--RKRAGWQCPECKVCQACRKPGNDS 286
C +C G L +L FC C +H CL+ A + W C CK C C + G S
Sbjct: 1204 CLLCASKG-LHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRGS 1262
Query: 287 K-MLVCETCDKGYHTFCLKPPMEELPAHS---WKCKACRVCRACGAGSAELNPNSEWFEN 342
K +L CE C YH CL P W C AC C++CGA + N + EW +
Sbjct: 1263 KHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGK-NWDVEWSGD 1321
Query: 343 YSLCHRCHKAQGGQTIRSVAEQHTPVCSR 371
YSLC RC T + P+C+R
Sbjct: 1322 YSLCPRC-------TQLYEKGNYCPICTR 1343
Score = 79.3 bits (194), Expect = 1e-13
Identities = 149/584 (25%), Positives = 196/584 (33%), Gaps = 103/584 (17%)
Query: 428 PQLEAPLNEEMPL----LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPL--PE 481
P E P E+ PL L P SP P P S P P + + P
Sbjct: 1810 PSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPN 1869
Query: 482 ALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSP-PP 540
RPL P P S P + P P PSP L+P PP
Sbjct: 1870 YSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSP-----LAPRPP 1924
Query: 541 EASPLSPPFEESPLS--PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE--- 595
+ SPP + SP PPP + T+ P + L+ PP +P PPPE+ + P E
Sbjct: 1925 PSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELA-PPGPAPSPPPPED--LGPDFEDME 1981
Query: 596 -------------ASRL-FPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP--- 638
AS L PF+E ++ S P ++S P + P
Sbjct: 1982 VVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTV 2041
Query: 639 ---PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPP--------PEAS 687
P +P S P R+ L V + E+ P + +P S P A
Sbjct: 2042 VSAPGLAP-SATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG 2100
Query: 688 RLSPPPEDSPT-----------------SPPPEDS--PASPPPEDSLMSLPLEESPLLP- 727
+ PPED P+ + P E+S PA P S S L SP P
Sbjct: 2101 DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT 2160
Query: 728 -----LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782
LP P + S GP +P P +P S L + +P P +
Sbjct: 2161 RTFAWLPGAPGVRVLSLGP--APEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQP 2218
Query: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCL 842
P P +SP A P L + P +P P P L+ SP +
Sbjct: 2219 PLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQ---- 2274
Query: 843 SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLS-------PLL 895
+S + P +P P K P A E+ P P G S +
Sbjct: 2275 --AIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVR 2332
Query: 896 GEPALSEPGEP-------------PLSPLPEE-LPLSPSGEPSL 925
G L PGEP PL PLPE+ P P G P L
Sbjct: 2333 GVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDL 2376
Score = 76.6 bits (187), Expect = 6e-13
Identities = 120/417 (28%), Positives = 156/417 (37%), Gaps = 83/417 (19%)
Query: 361 VAEQHTPVCSRFSPPEPGDTPTD-EPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPL 419
+A TP R + D TD E +A+ QP+G P PG ++ A L
Sbjct: 2047 LAPSATPGAPRIEQLDGVDDGTDSEAEAVQ-----QPRG---QGTPPSGPGVVR--AGVL 2096
Query: 420 GKAGVQLEPQLEAP---LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPA 476
G AG + P + P ++ + L P + P E P +PP + S P + L A
Sbjct: 2097 GAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPP--LANGSQPSQGLTA 2154
Query: 477 SPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPL-------------------EE 517
SP +R P +P L P PE P P E
Sbjct: 2155 SPADP----TRTFAWLPGAPGVRVLSLGPAPE--PPKPATSKIILVNKLGQVFVKMAGEG 2208
Query: 518 SPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
P+ PP + PP PP SP +P S PP L P R +PPP
Sbjct: 2209 EPVPPPVKQPPL---------PPTISPTAP---TSWTLPPGPLLGVLPVVGVVRPAPPPP 2256
Query: 578 ESPMSPPPEESPMSPPPEASRL--FPPFE-ESPLSPPPEESP-LSPPPEASRLSPPPEDS 633
P++ P SPP +A R+ F SP +PPP ++P L EAS ED+
Sbjct: 2257 PPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEAS------EDT 2310
Query: 634 PMSPPPEESPMS----PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRL 689
P P S P V + L + P P EESP P E S L
Sbjct: 2311 PQVPGLGSGGFSRVRMKTPTVRGVLDL-----------DRPGEPAGEESP-GPLQERSPL 2358
Query: 690 SPPPEDSP---TSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743
P PED P PP+ S S + EE P P +E Q P+ GPHL
Sbjct: 2359 LPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQ-APKRTGPHL 2414
Score = 72.8 bits (177), Expect = 9e-12
Identities = 113/449 (25%), Positives = 151/449 (33%), Gaps = 78/449 (17%)
Query: 766 EEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS 825
+E L + EE EE + E EE+ + + EE L P P P
Sbjct: 357 QEQKLDDEEEEK-----KEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAP 411
Query: 826 PQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP 885
P S P L P P P L PP PP PA EE PP
Sbjct: 412 SPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPP-------PP------PAQEEQEESPP 458
Query: 886 PGEPSLSPLLGEPALSEPGEPPLSPLPE-ELPLSPSGEPSLSPQLMPPDPL---PPPLSP 941
P P+ + G PPL+P E + +G SP P PP SP
Sbjct: 459 PVVPA-------TCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSP 511
Query: 942 IITAAAPPALSPLGELEYPFGAKG------------DSDPESP---LAAPILETPISPPP 986
+ + L + + P + D DP P +P+L PI+ P
Sbjct: 512 TVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSP 571
Query: 987 EANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNS-------PP 1039
P P P +P P +P P++P+ PLP + +L+ S PP
Sbjct: 572 ------PVPQEPAPVPSPPRAPTPPSTPV---PLPEKRRSILREPTFRWTSLTRELPPPP 622
Query: 1040 SQCSPPALPLSVPSPLS----PIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLP 1095
PP P P+P + P+ +E H E V P P P A P P
Sbjct: 623 PAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPP-PLGAPEAPEPEP 681
Query: 1096 SPMGDLSCPAPSPAP-------ALDDFSGLGEDTAPLDGIDAPGSQP---EPGQTPGSLA 1145
P D S P P +L F+ + T P+ +P P QT L
Sbjct: 682 PPADD-SPAEPEPRAVGRTNHLSLPRFAPV--VTTPVKAEVSPHGAPALSNGPQTQAQLL 738
Query: 1146 SELKGSPVLLDPEELAPVTPMEVYPECKQ 1174
L+ L P+ L P P P Q
Sbjct: 739 QPLQALQTQLLPQALPPPQPQLQPPPSPQ 767
Score = 72.0 bits (175), Expect = 2e-11
Identities = 150/637 (23%), Positives = 218/637 (34%), Gaps = 110/637 (17%)
Query: 735 CPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794
C + + L EE + EE + EE EE A EE L P
Sbjct: 353 CWKKQEQKLDDEEEE-----KKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLT 407
Query: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP-EESHLSP 853
P P L + P L P P P P P EE SP P + S
Sbjct: 408 PPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSR 467
Query: 854 ELEKPPLSP--RPEKPPEEPG------QCPAPEELPLFPPPGEPSLSPLLGE--PALSEP 903
+ +PPL+P R E+ G P P PP P+++P + +
Sbjct: 468 KRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQF 527
Query: 904 GEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGA 963
P +S + +P P P + P L P IT + P P P
Sbjct: 528 IMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEP---APVPSPP 584
Query: 964 KGDSDPESPLAAPILETPISPPPEANCTD-------PEPVPPMILPPSPGSPVGPAS--- 1013
+ + P +P+ P I P T P P PP PP+P P PA+
Sbjct: 585 RAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPP--PPAPSPPPAPATSSR 642
Query: 1014 -PILMEPLPPQCSPLLQHSLVPQN--SPPSQCSP----PALPLSVPSPLSPIGKVVGVSD 1066
P+L+ PQ +P H + ++ +PP +P P P + SP P + VG ++
Sbjct: 643 RPLLLR--APQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTN 700
Query: 1067 EAELHEME-------TEKVSEPECPALE--PSATSPLPSPMGDLSC-------------- 1103
L +VS PAL P + L P+ L
Sbjct: 701 HLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQL 760
Query: 1104 ---PAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEE- 1159
P+P P L+ G + PL G++ + SL K +D ++
Sbjct: 761 QPPPSPQQMPPLEKARIAGVGSLPLSGVE---------EKMFSLLKRAKVQLFKIDQQQQ 811
Query: 1160 -----LAPVTP----MEVYPECKQTAGQGSPCEE-------QEEPRAPVAPTPPTLIKSD 1203
P++P EV KQ + +G E +E P P +P IK
Sbjct: 812 QKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKH- 870
Query: 1204 IVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDS 1263
V + ++ G A A P P L + L+ E D S A + T+S
Sbjct: 871 -VCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATE-----DTSSASE-------TES 917
Query: 1264 LPETDDSLLCDAGTAISGGKAE--GEKGRRRSSPARS 1298
+P +A A GG++E G G +P RS
Sbjct: 918 VPSRSRRGKVEA--AGPGGESEPTGSGGTLAHTPRRS 952
Score = 72.0 bits (175), Expect = 2e-11
Identities = 134/528 (25%), Positives = 190/528 (35%), Gaps = 164/528 (31%)
Query: 407 KEPGPLQCEAKPLGKAGVQLE--PQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEA 464
+ P PL P A L+ PQL P + P L+ PP +P+ PPPE
Sbjct: 1914 RRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELA-PPGPAPSPPPPE- 1971
Query: 465 SRLSPPPEE------LPASPLPEALHL--SRPLEESPLSPPPEESPLSPP-----PESSP 511
L P E+ L A+ L A L + P +E ++ S P ESSP
Sbjct: 1972 -DLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSP 2030
Query: 512 FSPLEESPLS-------PPEESPPSPAL--------------ETPLSPPPEASPLSPP-- 548
S P++ P +P +P + E P + +P S P
Sbjct: 2031 TSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGV 2090
Query: 549 ------FEESPLSPPPEELPTS---------PPPEASRLSPPPEESPMSPP------PEE 587
+ PPE+LP+ P P E P +PP P +
Sbjct: 2091 VRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQ 2150
Query: 588 SPMSPPPEASRLFPPFEESP------LSPPPEESPLSPPPEASRL-----------SPPP 630
+ P + +R F +P L P PE P P S++
Sbjct: 2151 GLTASPADPTRTFAWLPGAPGVRVLSLGPAPE----PPKPATSKIILVNKLGQVFVKMAG 2206
Query: 631 EDSPMSPPPEESPMSPPPEVSRLSP-------------LPVVS--RLSPPPEESPLSPPP 675
E P+ PP ++ P+ PP +S +P LPVV R +PPP PL+
Sbjct: 2207 EGEPVPPPVKQPPL--PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVL 2264
Query: 676 EESPTSPPPEA---SRLSPPPEDSPTSPPP-------------EDSPASP---------- 709
P SPP +A R+S SP +PPP ED+P P
Sbjct: 2265 SSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRV 2324
Query: 710 ----PPEDSLMSL-------------PLEE-SPLLPLPEE--PQLCPRSEGPHLSPRPEE 749
P ++ L PL+E SPLLPLPE+ PQ+ +GP
Sbjct: 2325 RMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQV---PDGP-------- 2373
Query: 750 PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797
P L + H S +A S EEP + ++ + +P+ GPHL
Sbjct: 2374 PDLLLESQWHHYSGEA-----SSSEEEP--PSPDDKENQAPKRTGPHL 2414
Score = 70.9 bits (172), Expect = 3e-11
Identities = 113/415 (27%), Positives = 143/415 (34%), Gaps = 81/415 (19%)
Query: 2181 PAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPST 2240
P PL P P+ PP PP + P PP PP +P PS
Sbjct: 402 PPPPLTPPAPSPPPPLPPPSTSPPPPLCPP-----------------PPPPVSPPPLPSP 444
Query: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSP--- 2297
P P P + P P K P L+P E R+A E +P
Sbjct: 445 PPP---PAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAE-REAARAGPEGTSPPTPTPS 500
Query: 2298 --SYGPPNLGFVDSPSSGTHLGGLE--------------LKTPDVFKAPLTPRASQVE-- 2339
+ GPP +P S T L + +KTP F P+ +VE
Sbjct: 501 TATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVS 560
Query: 2340 ----PQSPGLGLRPQEPPPAQA--LAPSPPSHPDIF---RPGSYTDPYAQPPLTPRPQPP 2390
P PQEP P + AP+PPS P R +P + R PP
Sbjct: 561 PVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP 620
Query: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPY 2450
PP A PP PS P P +SS+ PL L A F PS +
Sbjct: 621 PPP---APPPPPAPSPP-------PAPATSSRRPLL---LRAPQFTPSEAHLKIYESVLT 667
Query: 2451 SRPPSRPQSRDPFAPL--HKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHA 2508
P P++ +P P P P+P V G H SL P P + A
Sbjct: 668 PPPLGAPEAPEPEPPPADDSPAEPEPRAV----GRTNHLSL-----PRFAPV-VTTPVKA 717
Query: 2509 KVPSGQPPNFVRSPGTGAFVGTPSPMRFT--FPQAV--GEPSLKPPVPQPGLPPP 2559
+V P P T A + P T PQA+ +P L+PP P P PP
Sbjct: 718 EVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPP-PSPQQMPP 771
Score = 69.3 bits (168), Expect = 1e-10
Identities = 164/669 (24%), Positives = 216/669 (32%), Gaps = 132/669 (19%)
Query: 604 EESPLSPPPEESPLSPPPEASRL--SPPPEDSPMS--PPPEESPMSPPPEVSRLSPLPVV 659
E P P E + L E + SP P P PP ++ + P R SP +
Sbjct: 1782 EYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSP---I 1838
Query: 660 SRLSPPPEESPLSPPPEESPTSPPPEASRLSPP----PEDSPTSPPPEDSPASPPPEDSL 715
L PP L P +S ++PPP S P SP+ P P P
Sbjct: 1839 QNLDPP-----LRP---DSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGS 1890
Query: 716 MSLPLEESPLLPLPEEPQLCPRSEGPH-LSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP 774
S P + P+ P RS P L+PRP + P + SPQ P P
Sbjct: 1891 PSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKT--SPQLRVP----PP 1944
Query: 775 EEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLS 834
P L+P GP SP P E L P E+ + L
Sbjct: 1945 TSVVTALTPTSGELAPP--GPAPSPPPPE-DLGPDFEDMEVVSGLSAADLDFAASLLGTE 2001
Query: 835 PQSEEPCLSPRPEESHLSP----ELEKPPLSPR---PEKPPEEPGQCPAPEELPLFPPPG 887
P EE + SH P E E P S P PG P+ PG
Sbjct: 2002 PFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSAT-------PG 2054
Query: 888 EPSLSPLLG--------EPALSEP---GEPPLSP-LPEELPLSPSGEPSLSPQLMPPDPL 935
P + L G A+ +P G PP P + L +G+ + PP+ L
Sbjct: 2055 APRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGD-----RARPPEDL 2109
Query: 936 PPPLSP-IITAAAPPALSPLGELEY-----PFGAKGDSDPESPLAAPILET------PIS 983
P + ++ P G E P A G + A+P T P +
Sbjct: 2110 PSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGA 2169
Query: 984 PPPEANCTDPEPVPP----------------MILPPSPGSPVGPASPILMEPLPPQCSPL 1027
P P P PP + G PV P P+ PLPP SP
Sbjct: 2170 PGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPP--PVKQPPLPPTISP- 2226
Query: 1028 LQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE 1087
+P S PP PL + VVGV A + PA
Sbjct: 2227 --------TAPTSWTLPPG-------PLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASP 2271
Query: 1088 PSATSPLP--SPMGDLSCPAPSP--APALDDFSGLGEDTAPLDG---------------- 1127
P + S S PAP P AP LD+ EDT + G
Sbjct: 2272 PRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTV 2331
Query: 1128 -----IDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPC 1182
+D PG +P ++PG L P+ D P P ++ E + G
Sbjct: 2332 RGVLDLDRPG-EPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEAS 2390
Query: 1183 EEQEEPRAP 1191
+EEP +P
Sbjct: 2391 SSEEEPPSP 2399
Score = 62.8 bits (151), Expect = 9e-09
Identities = 101/423 (23%), Positives = 146/423 (34%), Gaps = 61/423 (14%)
Query: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP 903
PR E +HL E + P E PG P + + P SP+ L P
Sbjct: 1788 PREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQN---LDPP 1844
Query: 904 GEPPLSPLPEELPLSPSGE----PSLSPQLMPPD-----PLPPPLSPIITAAAPPALSPL 954
P P P S SG P+ SP P PLP P SP ++ + +
Sbjct: 1845 LRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSP---SSLTHHIPTV 1901
Query: 955 GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASP 1014
G+ ++P + P SPLA PPP + P P + P P S V +P
Sbjct: 1902 GDPDFPAPPRRSRRP-SPLAP-------RPPPSRWASPPLKTSPQLRVPPPTSVVTALTP 1953
Query: 1015 ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSP---------IGKVVGVS 1065
E PP P PP P + V S LS +G
Sbjct: 1954 TSGELAPP--------GPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQE 2005
Query: 1066 DEAELHEMETEKVSEPECPALEPSATSP-LPSPMGDLSCPAPSP-----APALDDFSGLG 1119
+ M + + E S TS + P+ +S P +P AP ++ G+
Sbjct: 2006 EIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVD 2065
Query: 1120 EDT-APLDGIDAPGSQPEPGQTPGSLASELKGS--PVLLDPEELAPVTPMEVYPECKQTA 1176
+ T + + + P Q P PG + + + G+ PE+L P E+ +
Sbjct: 2066 DGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDL----PSEIVDFVLKNL 2121
Query: 1177 GQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASF------PGSEPLLGSP 1230
G P + PR P P L ++ S D + +F PG L P
Sbjct: 2122 --GGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGP 2179
Query: 1231 DPE 1233
PE
Sbjct: 2180 APE 2182
Score = 61.6 bits (148), Expect = 2e-08
Identities = 159/638 (24%), Positives = 207/638 (32%), Gaps = 107/638 (16%)
Query: 472 EELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP--PEESPPS 529
E P P E HL E + P +P S PP PL+ L P PE P
Sbjct: 1782 EYRPWGPREEPAHLEAAEENQTIVHSP--APSSEPPGGED-PPLDTDVLVPGAPERHSPI 1838
Query: 530 PALETPLSPPPEASPLSPPFEESPLS-PPPEELPTSPPPEASRLSPPPEESPMSP----- 583
L+ PL P ++P P S P P+ P P P SP SP
Sbjct: 1839 QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLP--SPGSPSSLTH 1896
Query: 584 --PPEESPMSP-PPEASRLFPPFEESP-----LSPPPEESPLS--PPPEASRLSPPPEDS 633
P P P PP SR P P SPP + SP PPP + + P
Sbjct: 1897 HIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSG 1956
Query: 634 PMSPP-PEESPMSPPPE-----------VSRLSPLPV---VSRLSPPPEESPL------- 671
++PP P SP PPPE VS LS + S L P + +
Sbjct: 1957 ELAPPGPAPSP--PPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMG 2014
Query: 672 --------SPPPEESPTS-----PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718
S E SPTS P S P +P +P E DS
Sbjct: 2015 SSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEA 2074
Query: 719 PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP-HLSPQPEEP 777
+ P P + R P P + P P E
Sbjct: 2075 VQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREE 2134
Query: 778 CLCAVPEEPHLSPQAEGPHLSPQPEE-----LHLSPQTEEPHLSPVPEEPCLSPQPEESH 832
L P + S ++G SP L +P L P PE P P +
Sbjct: 2135 SLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPP--KPATSKII 2192
Query: 833 LSPQSEEPCLSPRPEESHLSPELEKPPLSP--RPEKP-----PEEP--GQCPAPEELPLF 883
L + + + E + P +++PPL P P P P P G P +
Sbjct: 2193 LVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPA 2252
Query: 884 PPPGEPSLSPLLGEPALSEP-------------GEPPLSPLPEELP-LSPSGEPSLSPQL 929
PPP P L+ +L S P G P +P P + P L GE S
Sbjct: 2253 PPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEAS----- 2307
Query: 930 MPPDPLPPPLSP---IITAAAPPALSPLGELEYPFGAKGDSDPESPL--AAPILETPISP 984
P P L P + + +L+ P G+ P PL +P+L P
Sbjct: 2308 -EDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESP-GPLQERSPLLPLPEDG 2365
Query: 985 PPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPP 1022
PP+ P+ P ++L G AS EP P
Sbjct: 2366 PPQV----PDGPPDLLLESQWHHYSGEASSSEEEPPSP 2399
Score = 58.9 bits (141), Expect = 1e-07
Identities = 134/580 (23%), Positives = 190/580 (32%), Gaps = 100/580 (17%)
Query: 2100 PALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGEL 2159
P +L P +P + +PPPA P F G+ S S G +P P SP L
Sbjct: 1837 PIQNLDPPLRPDSGSAPPPA--PRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSL 1894
Query: 2160 FLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGA----- 2214
+P P +P PR P P P P+ A PP+ +
Sbjct: 1895 THHIPTVGD------------PDFPAPPRRSRRPSPLAPRPPPS-RWASPPLKTSPQLRV 1941
Query: 2215 ---SSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEP 2271
+S A P PPG PS P P + P +++ V +
Sbjct: 1942 PPPTSVVTALTPTSGELAPPGP---APSPPPP--EDLGPDFEDMEVVSGLSAADLDFAAS 1996
Query: 2272 LLSPPPFGE---SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFK 2328
LL PF E + A+ G SS P ++ P + GL
Sbjct: 1997 LLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSA----- 2051
Query: 2329 APLTPRASQVEPQSPGLGLRPQ--EPPPAQALAPSPPSHPDIFRPG--SYTDPYAQPP-- 2382
P PR Q++ G + + P Q +PPS P + R G A+PP
Sbjct: 2052 TPGAPRIEQLDGVDDGTDSEAEAVQQPRGQG---TPPSGPGVVRAGVLGAAGDRARPPED 2108
Query: 2383 --------------------LTPRPQ---PPPPESCCALPPRSL---PSDP---FSRVPA 2413
PR + P PP + + P + L P+DP F+ +P
Sbjct: 2109 LPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPG 2168
Query: 2414 SP--QSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPR 2471
+P + S +P P+P +++ + + F P P + P P P
Sbjct: 2169 APGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTA 2228
Query: 2472 PQ----PPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAF 2527
P PP G L + P P P + + P+ P +R F
Sbjct: 2229 PTSWTLPPGPLL--GVLPVVGVVRPAPPP--PPPPLTLVLSSGPASPPRQAIRVKRVSTF 2284
Query: 2528 VG--TPSPMRFTFPQAVGEPSLKPPVPQ-PGLPPPHGINSHFGPGPTLGKPQSTNYTVAT 2584
G P+P + P+ + PQ PGL G G T
Sbjct: 2285 SGRSPPAPPPYKAPRLDEDGEASEDTPQVPGL----------GSGGFSRVRMKTPTVRGV 2334
Query: 2585 GNFHPSGSPLGPSSGSTGESYGLSPLRP-PSVLPPPAPDG 2623
+ G P G S G SPL P P PP PDG
Sbjct: 2335 LDLDRPGEPAGEE--SPGPLQERSPLLPLPEDGPPQVPDG 2372
Score = 57.8 bits (138), Expect = 3e-07
Identities = 165/734 (22%), Positives = 240/734 (32%), Gaps = 125/734 (17%)
Query: 1797 PSFGLGTPKAKGDGGSERKELPTSQKGDD-GPDIADEESRGLEGKADTPGPEDGGVKASP 1855
PS G + DG S+ +E +D P R G+A P K +P
Sbjct: 103 PSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSSLRSALRSQRGRA--PRGRGRKHKTTP 160
Query: 1856 VPSD------PEKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLGC 1909
+P P P TP R EE + + L +L + + + C
Sbjct: 161 LPPPRLADVAPTPPKTPA---------RKRGEEGTERMVQALTELLRRAQAPQAPRSRAC 211
Query: 1910 --GTPGLEGSRTPLQRPF-----LQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFF 1962
TP R P RP Q + + + P P P + + + G +
Sbjct: 212 EPSTPRRSRGRPP-GRPAGPCRRKQQAVVVAEAAVTIPKPEPP----PPVVPVKHQTGSW 266
Query: 1963 SPEPGEPDSPWTGS-GGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPV 2021
+ G P T GG + G G GL + + + R +K ++GQLS
Sbjct: 267 KCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKK-VKMGQLSLGLES 325
Query: 2022 LYANINFPNLKQDYPDWSSRCKQI-MKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQA 2080
QD P Q W+K ++ D+ + + +K
Sbjct: 326 GQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQ---------EQKLDDEEEEKKEEEEKDK 376
Query: 2081 ESQINKQTKVGD-IARKTDRPALHLRIPP-QPGALGSPPPAAAPTIFIGSPTTPAGLSTS 2138
E + ++ V + + ++ L PP P A PPP P+ P P
Sbjct: 377 EGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPV 436
Query: 2139 ADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQ----------VPSQ---------DPFGL 2179
+ PP S P P + E PP VPA PSQ P G
Sbjct: 437 SP----PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGT 492
Query: 2180 APAYPLEPRFPTAPPTYPPYPSPTGAPAQP-----------PMLGASSRPGAGQPGEF-H 2227
+P P P+ PP SPT AP P++ A S P F
Sbjct: 493 SPPTPT----PSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMD 548
Query: 2228 TTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG--VGGGKASEPLLSPPPFGESRKAL 2285
PP P+ + S P L+P P + VP+ P +A P +P P E R+++
Sbjct: 549 EDPPKPPKVEVS---PVLRP--PITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSI 603
Query: 2286 EVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGL 2345
+ S PP P AP P A + P L
Sbjct: 604 LREPTFRWTSLTRELPP-----------------PPPAPPPPPAPSPPPAPATSSRRPLL 646
Query: 2346 GLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALP-PRS-- 2402
PQ P +H I+ T P P P P+PPP + A P PR+
Sbjct: 647 LRAPQFTP--------SEAHLKIYE-SVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVG 697
Query: 2403 ----LPSDPFSRVPASPQSQSSSQ--SPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456
L F+ V +P S +P +A P+ P + PP +
Sbjct: 698 RTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQ 757
Query: 2457 PQSRDPFAPLHKPP 2470
PQ + P +P PP
Sbjct: 758 PQLQPPPSPQQMPP 771
Score = 57.4 bits (137), Expect = 4e-07
Identities = 162/658 (24%), Positives = 209/658 (31%), Gaps = 139/658 (21%)
Query: 2384 TPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTP-RPLSAEAFCPSPVT- 2441
+P P PP P D VP +P+ S Q+ P RP S A P+P +
Sbjct: 1807 SPAPSSEPPGG------EDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF 1860
Query: 2442 --PRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAH--TSLGAGGFPAA 2497
R + P+ YS P RP F PL P P SL H ++G FPA
Sbjct: 1861 SGARIKVPN-YS-PSRRPLGGVSFGPLPSPGSPS---------SLTHHIPTVGDPDFPA- 1908
Query: 2498 LPAGPAGELHAKVPSGQPPNFVRSP-GTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGL 2556
P + P P + P T + P P L PP P P
Sbjct: 1909 -PPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSP 1967
Query: 2557 PPPHGINSHFG---------------PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGST 2601
PPP + F LG VA G S GP S
Sbjct: 1968 PPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHG--GPGDSSE 2025
Query: 2602 GESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAEL 2661
ES S V AP G P + GA + +E+ + G S +
Sbjct: 2026 EESSPTSRYIHFPVTVVSAP-GLAPSATPGAPR-------IEQLDGVDDGTDSEAEAVQQ 2077
Query: 2662 P---GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPG 2718
P GT G + L R R E L E +G PG
Sbjct: 2078 PRGQGTPPSGPGVVRAGVLGAAGDRARPPEDL------------PSEIVDFVLKNLGGPG 2125
Query: 2719 SWGAEP---SSPAFEQLSRGQTPFAG--------TQDKSSLVGLPPSKLSGPILGPGSFP 2767
GA P S P L+ G P G T+ + L G P ++ LGP
Sbjct: 2126 DGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLS--LGPA--- 2180
Query: 2768 SDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAAT 2827
PP PAT + VN Q F + A +P +Q L TA T
Sbjct: 2181 -----PEPPKPATSKIILVNKL-----GQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPT 2230
Query: 2828 SMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEP------VPGPAG-PAQFIEL 2880
S + PGP LG P+ G+ P P P GPA P Q I +
Sbjct: 2231 S--------WTLPPGPLLG----VLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRV 2278
Query: 2881 RHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAP 2940
+ + F G+ PP P + D A E P P
Sbjct: 2279 KR---------VSTFSGRSPPAPPPYKAPRLDEDGEASE---------------DTPQVP 2314
Query: 2941 ELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCED---PELDD 2995
L + K PT+ L+L +RP P PL + LP + P++ D
Sbjct: 2315 GLGSGGFSRVRMKTPTVRGVLDL-DRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPD 2371
Score = 54.3 bits (129), Expect = 3e-06
Identities = 76/306 (24%), Positives = 108/306 (35%), Gaps = 53/306 (17%)
Query: 2331 LTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP 2390
+ P A + E + P PPP APSPP P + P T P PPL P P PP
Sbjct: 390 MMPAAEKEEAKLP--------PPPLTPPAPSPP--PPL--PPPSTSP--PPPLCPPPPPP 435
Query: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPY 2450
+ P LPS P P + + Q S P+ P S + P P+TP ++
Sbjct: 436 -------VSPPPLPSPP---PPPAQEEQEESPPPVVPATCSRKRGRP-PLTPSQRAEREA 484
Query: 2451 SRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKV 2510
+R + P+ P P PPE + + T L + V
Sbjct: 485 AR--AGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKN-----------IRQFIMPV 531
Query: 2511 PSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP-SLKPPVPQPGLPPPHGINSHFGPG 2569
S + +++P P P + + P + PPVPQ P P + P
Sbjct: 532 VSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPS 591
Query: 2570 PTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLS 2629
+ P+ + F + T E L PP PPP P S P
Sbjct: 592 TPVPLPEKRRSILREPTFR--------WTSLTRE------LPPPPPAPPPPPAPSPPPAP 637
Query: 2630 HGASQR 2635
+S+R
Sbjct: 638 ATSSRR 643
Score = 53.9 bits (128), Expect = 4e-06
Identities = 139/594 (23%), Positives = 195/594 (32%), Gaps = 139/594 (23%)
Query: 2495 PAALPAGPAGE--LHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP------S 2546
PA L A + +H+ PS +PP P + +P R + Q + P S
Sbjct: 1792 PAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGS 1851
Query: 2547 LKPPVPQ-------------PGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSP 2593
PP P+ P P G++ FGP P+ G P S + + T G P
Sbjct: 1852 APPPAPRSFSGARIKVPNYSPSRRPLGGVS--FGPLPSPGSPSSLTHHIPT-----VGDP 1904
Query: 2594 LGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMG 2653
P+ S SPL P PPP+ S P + + TS V +
Sbjct: 1905 DFPAPPR--RSRRPSPLAPR---PPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELA 1959
Query: 2654 SSLATAELPGTQDPG--------MSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKE 2705
P +D G +SGLS +L+ + ++E
Sbjct: 1960 PPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLD-----------FAASLLGTEPFQEEIV 2008
Query: 2706 TAAAAAGAVGPPGSWGAEPSSPAFEQ------------LSRGQTPFA-----------GT 2742
A A + G PG E SSP L+ TP A GT
Sbjct: 2009 AAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGT 2068
Query: 2743 QDKSSLV------GLPPSKLSGP-ILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS 2795
++ V G PPS GP ++ G + +RPP +D + L G
Sbjct: 2069 DSEAEAVQQPRGQGTPPS---GPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPG 2125
Query: 2796 Q--AFYQRAPYPGSLPLQQQQQQLWQQQQATA-----------ATSMRFAMSARFPSTPG 2842
A + P + PL Q + A A +R P P
Sbjct: 2126 DGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPK 2185
Query: 2843 PELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQ 2902
P + L + L + ++ G GEPVP P + PP
Sbjct: 2186 PATSKIILVNKLGQVFVKMAGEGEPVPPPV-------------------------KQPPL 2220
Query: 2903 RPRFYPVSEDPHRLAPEGLRG-LAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGL 2961
P P + L P L G L V G+ P PP P L L + GP P
Sbjct: 2221 PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAP-PPPPPPLTLVL-----SSGPASPP-R 2273
Query: 2962 ELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLG 3015
+ + ST GR P P + P LD+D +A ED ++ LG G
Sbjct: 2274 QAIRVKRVSTFSGRSPP-----APPPYKAPRLDEDGEAS---EDTPQVPGLGSG 2319
Score = 53.1 bits (126), Expect = 7e-06
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Query: 133 GGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGASIPCRSPGCPRL 192
G + W H CA WSA V+ + L V A+ G RC C + GA++ C C
Sbjct: 1602 GQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSN 1661
Query: 193 YHFPCATASGSFLSMKTLQLLCPEHSE 219
+HF CA AS + ++ C +H++
Sbjct: 1662 FHFMCARAS-YCIFQDDKKVFCQKHTD 1687
Score = 52.8 bits (125), Expect = 1e-05
Identities = 123/511 (24%), Positives = 170/511 (33%), Gaps = 82/511 (16%)
Query: 2095 RKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPD 2154
R++ RP+ PP P SPP +P + + PT+ T G L PP G P P
Sbjct: 1911 RRSRRPSPLAPRPP-PSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPP-GPAPSPP 1968
Query: 2155 SPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGA 2214
P +L P +V S GL+ A + F + P+ A
Sbjct: 1969 PPEDLG---PDFEDMEVVS----GLSAA---DLDFAASLLGTEPFQEEIVAAGAM----G 2014
Query: 2215 SSRPGAGQPGEFHTTPPGTPRHQPSTP------DPFLKPRCPSLDNLAVPESPGVGGGKA 2268
SS G G E ++P H P T P P P ++ L GV G
Sbjct: 2015 SSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQL-----DGVDDGTD 2069
Query: 2269 SEPLLSPPPFGESRKAL---EVKKEELGASSPSYGPPN------LGFVDSPSSGTHLGGL 2319
SE P G+ V+ LGA+ PP + FV G GG
Sbjct: 2070 SEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGA 2129
Query: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYA 2379
+ + AP P A+ +P S GL P +P A P P +
Sbjct: 2130 GPREESLPPAP--PLANGSQP-SQGLTASPADPTRTFAWLPGAPGVRVL----------- 2175
Query: 2380 QPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP 2439
L P P+PP P + + + + +V + P +P P P
Sbjct: 2176 --SLGPAPEPPKPAT-----SKIILVNKLGQVFVKMAGEGEPVPPPVKQP-------PLP 2221
Query: 2440 VTPRFQSPDPYSRPPSRPQSRDPFAPLHKP-PRPQPPEVAFKAGS-----------LAHT 2487
T +P ++ PP P + +P P P PP + S +
Sbjct: 2222 PTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRV 2281
Query: 2488 SLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSL 2547
S +G P A P A L + + V G+G F S +R P G L
Sbjct: 2282 STFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGF----SRVRMKTPTVRGVLDL 2337
Query: 2548 KPPVPQPG--LPPPHGINSHFGPGPTLGKPQ 2576
P G P P S P P G PQ
Sbjct: 2338 DRPGEPAGEESPGPLQERSPLLPLPEDGPPQ 2368
Score = 51.6 bits (122), Expect = 2e-05
Identities = 129/541 (23%), Positives = 186/541 (34%), Gaps = 152/541 (28%)
Query: 4054 TPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGG 4113
TP + + P PS S L P P P S L P P Q++Q
Sbjct: 407 TPPAPSPPPPLPPPSTSPPPPLC---PPPPPPVSPPPLPSPPPPPAQEEQ---------- 453
Query: 4114 GSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPP 4173
E S P + A S G P L Q+ E G PP
Sbjct: 454 ------------EESPPPVVPATCSRKRGRPP------LTPSQRAEREAARAGPEGTSPP 495
Query: 4174 KPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQ 4233
P P +G G +P + S + ++ +M +
Sbjct: 496 TPTPSTATG--------------------GPPEDSPTVAPKSTTFLKNIRQFIMPVVSAR 535
Query: 4234 SQAVRQTP-------PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP 4286
S V +TP P + P + SP+ P T P P PQ P
Sbjct: 536 SSRVIKTPRRFMDEDPPKPPKVEVSPVLR-----------PPITTSP-------PVPQEP 577
Query: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSS-PQEPKRPSQLPSPSSQLPT-EAQLPPTHPGTP 4344
+P+PP A PTPP + P KR S L P+ + + +LPP P P
Sbjct: 578 APVPSPPRA-----------PTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPP 626
Query: 4345 KPQGPTLEPPPG------------RVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQS 4392
P P+ P P + +P+ A L ++ L P PP E +PE
Sbjct: 627 PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHL--KIYESVLTP--PPLGAPEAPEPE-- 680
Query: 4393 SLVPGHLDQVNGQVVPEA----SQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNH 4448
P D + P A + LS+ PR P VK E + P GAP SN
Sbjct: 681 ---PPPADDSPAEPEPRAVGRTNHLSL---PRFAPVV--TTPVKAEVS--PHGAPALSN- 729
Query: 4449 LLLAGPRSEAGHL---------LLQKLLRAKNVQLSTGRGSEGL----RAEINGHIDSKL 4495
GP+++A L LL + L QL + + +A I G L
Sbjct: 730 ----GPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPL 785
Query: 4496 AGLEQKL------------QGTPSNKEDAAARKPLTPKPKRVQKA-SDRLVSSRKKLRKE 4542
+G+E+K+ + ++ AA PL+P + + A + + +S R +R E
Sbjct: 786 SGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSE 845
Query: 4543 D 4543
D
Sbjct: 846 D 846
Score = 50.4 bits (119), Expect = 5e-05
Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 4905 QLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
+L PP P+P P P P P++ P PL P P++ PP+PSP P + E P
Sbjct: 400 KLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPP 459
Query: 4965 ARPPE-EGEDSRPP 4977
P + RPP
Sbjct: 460 VVPATCSRKRGRPP 473
Score = 47.0 bits (110), Expect = 5e-04
Identities = 114/484 (23%), Positives = 166/484 (34%), Gaps = 82/484 (16%)
Query: 4309 PPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR----VSPAAAQ 4364
PPP +P P P LP PS+ P PP P +P P P+ PPP + SP
Sbjct: 403 PPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL-PSPPPPPAQEEQEESPPPVV 461
Query: 4365 LADTLFSKGLGPWDP---PDNLAETQKPEQS-------SLVPGHLDQVNGQVVPEASQL- 4413
A +G P P + A PE + S G + + V P+++
Sbjct: 462 PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFL 521
Query: 4414 -SIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNV 4472
+I+Q A ++ +K P P+ E +L + + V
Sbjct: 522 KNIRQFIMPVVSARSSRVIKTPRRFMDEDPP--------KPPKVEVSPVLRPPITTSPPV 573
Query: 4473 QLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARK-----PLTPKPKRVQK 4527
RA L + + P+ + + R+ P P P
Sbjct: 574 PQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSP 633
Query: 4528 ASDRLVSSRKK-LRKEDGVRASEALLKQLKQELSLLPLTEPAI----------------- 4569
SSR+ L + SEA LK + L+ PL P
Sbjct: 634 PPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEP 693
Query: 4570 -----TANFSL--FAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTP 4622
T + SL FAP + PV + GA AL GP +QLL
Sbjct: 694 RAVGRTNHLSLPRFAPVVT-TPVKAEVSPHGA---PALSNGPQTQAQLLQPLQALQTQLL 749
Query: 4623 PSSLPP-----TPPPSVQQ------KMVNGVTPSEELGEHPKDAASARDSERALRDTSEV 4671
P +LPP PPPS QQ + GV G K + + ++ L +
Sbjct: 750 PQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQ 809
Query: 4672 KSLDLLAALPTPPHNQTEDVRMESDEDSD-----SPDSIVPA-----SSPESILGEEAPR 4721
+ + A++P P Q E+V + SD S D V A S PES + + PR
Sbjct: 810 QQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPV--QGPR 867
Query: 4722 FPHL 4725
H+
Sbjct: 868 IKHV 871
Score = 45.4 bits (106), Expect = 0.002
Identities = 117/567 (20%), Positives = 193/567 (34%), Gaps = 97/567 (17%)
Query: 377 PGDTPTDEPDALYVACQGQPKGGHVTSMQPKEP----GPLQCEAKPLGKAGVQLEPQLEA 432
P TP++ +Y + P G + +P+ P P + E + +G+ P+
Sbjct: 650 PQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFA- 708
Query: 433 PLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES 492
P++ P ++ +SP + ++ P ++L P + L LP+AL
Sbjct: 709 ------PVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALP-------- 754
Query: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552
P + L PPP PLE++ ++ P S E S A ++
Sbjct: 755 -----PPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQ 809
Query: 553 PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP 612
+P SP + ++ ++ P S EA R P ESP+ P
Sbjct: 810 QQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDES--VEAKRERPSGPESPVQGP- 866
Query: 613 EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS 672
R+ + ++ + + P +V RLS LP+ R E++ +
Sbjct: 867 ------------RIKHVCRHAAVALGQARAMV--PEDVPRLSALPLRDRQDLATEDTSSA 912
Query: 673 PPPEESPT-SPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE- 730
E P+ S + P E PT + P SL S ++ +
Sbjct: 913 SETESVPSRSRRGKVEAAGPGGESEPTG---SGGTLAHTPRRSLPSHHGKKMRMARCGHC 969
Query: 731 ----EPQLC---------PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPH-----LSP 772
Q C P+ GP+ + + E + A++ L P
Sbjct: 970 RGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRTIVKTLLP 1029
Query: 773 --QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEE 830
E P P P A GP EE+ P EE ++
Sbjct: 1030 WDSDESPEASPGPPGPRRGAGAGGPR-----EEVVAHPGPEE----------------QD 1068
Query: 831 SHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP----- 885
S L +S C+ RP S ++ + P PP + P ELPL P
Sbjct: 1069 SLLQRKSARRCVKQRP-----SYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSR 1123
Query: 886 PGEPSLSPLLGEPALSEPGEPPLSPLP 912
P +P+L P+L A + L+P P
Sbjct: 1124 PRKPTLQPVLQLKARRRLDKDALAPGP 1150
Score = 44.3 bits (103), Expect = 0.003
Identities = 80/358 (22%), Positives = 117/358 (32%), Gaps = 67/358 (18%)
Query: 4646 EELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSI 4705
E+ E KD ERA+ + + A LP PP + S P
Sbjct: 367 EKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPP--------LTPPAPSPPPPLP 418
Query: 4706 VPASSPESILGEEAP---RFPHLGSG----RWEQEDRALSPVIPLI---PRASIPVFPDT 4755
P++SP L P P L S E+++ + PV+P R P+ P
Sbjct: 419 PPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQ 478
Query: 4756 KPY------GALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSM 4809
+ G G P P T G + + S KN+ ++ V S
Sbjct: 479 RAEREAARAGPEGTSPPTPTPSTA-TGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSS 537
Query: 4810 KIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTL 4869
++ + E P + P E + P T + Q A +P
Sbjct: 538 RVIKTPRRFMDEDPPK------------PPKVEVSPVLRPPITTSPPVPQEPAPVPSPPR 585
Query: 4870 KSQLDILSLLKQESPAPEPPTQHSY----TYNVSNLDVRQLSAPPPEEPSPPPSPLAPSP 4925
+P P P + S T+ ++L R+L PPP P PP P+P
Sbjct: 586 APT-------PPSTPVPLPEKRRSILREPTFRWTSL-TRELPPPPPAPPPPPAPSPPPAP 637
Query: 4926 ASPPTEPLV------------------ELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965
A+ PL+ L PL P P P P + A P+PRA
Sbjct: 638 ATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRA 695
Score = 43.5 bits (101), Expect = 0.006
Identities = 81/359 (22%), Positives = 119/359 (33%), Gaps = 80/359 (22%)
Query: 4644 PSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPD 4703
P +G + + E+ L D E K + +D E E+ +
Sbjct: 340 PQRRVGSGQGGSPCWKKQEQKLDDEEEEKK-----------EEEEKDKEGEEKEERAVAE 388
Query: 4704 SIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGL 4763
++PA+ E P P S + SP PL P PV P
Sbjct: 389 EMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPP-------- 440
Query: 4764 EVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESP 4823
+P P E+ + S V+ A G + P +
Sbjct: 441 -LPSPPPPPAQEEQEESPPPVV----PATCSRKRG-----------RPPLTPSQRAEREA 484
Query: 4824 ARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDW------LKQFDAVLPGYTLKSQLDILS 4877
ARAG E P G SP P ++QF ++P + +S I +
Sbjct: 485 ARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQF--IMPVVSARSSRVIKT 542
Query: 4878 LLK-QESPAPEPPTQHSYTYNVSNLDVRQLSAPP-------PEEPSPPPSP-LAPSPASP 4928
+ + P+PP ++V + PP P+EP+P PSP AP+P S
Sbjct: 543 PRRFMDEDPPKPP----------KVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPST 592
Query: 4929 PT-----------EPLV-------ELPTEPLAEPPVPSPLPLASSPESARPKPRARPPE 4969
P EP ELP P A PP P+P P + S+R R P+
Sbjct: 593 PVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQ 651
Score = 43.5 bits (101), Expect = 0.006
Identities = 160/676 (23%), Positives = 215/676 (31%), Gaps = 160/676 (23%)
Query: 2349 PQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ---------PPLTPRPQPPPPESCCALP 2399
P+ P Q L PP PD GS P + P +P +P S LP
Sbjct: 1832 PERHSPIQNL--DPPLRPD---SGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLP 1886
Query: 2400 PRSLPSDPFSRVPA-------SPQSQSSSQSPLTPRPLSAE-AFCPSPVTPRFQSPDPYS 2451
PS +P +P +S SPL PRP + A P +P+ + P P S
Sbjct: 1887 SPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTS 1946
Query: 2452 RPPSRPQSRDPFAPLHKPPRPQPPE------------VAFKAGSL--AHTSLGAGGFPAA 2497
+ + AP P P PPE A L A + LG F
Sbjct: 1947 VVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEE 2006
Query: 2498 L-PAGPAGELHAKVPSGQPPNFVRSPG-TGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPG 2555
+ AG G H PG + +P+ FP V P PG
Sbjct: 2007 IVAAGAMGSSHG------------GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPG 2054
Query: 2556 LPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSS---------GSTGESYG 2606
P ++ G T+ + A P G PS G+ G+
Sbjct: 2055 APRIEQLD---------GVDDGTD-SEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDR-- 2102
Query: 2607 LSPLRPPSVLPPPAPDGSLPYL----SHGASQRSGI---TSPVEKREDPGTGMGSSLAT- 2658
RPP LP D L L GA R P+ P G+ +S A
Sbjct: 2103 ---ARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADP 2159
Query: 2659 ----AELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAV 2714
A LPG PG+ LS + + + +L+ N L Q A V
Sbjct: 2160 TRTFAWLPGA--PGVRVLSLGPAPEPPKPATSKIILV------NKLGQVFVKMAGEGEPV 2211
Query: 2715 GPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSG--PILGPGSFPSDDRL 2772
PP P P + T LPP L G P++G
Sbjct: 2212 PPP------VKQPPLPPTISPTAPTSWT--------LPPGPLLGVLPVVGVVR------- 2250
Query: 2773 SRPPPPATPSSMDVNSRQLVGGSQA--------FYQRAPYPGSLPLQQQQQQLWQQQQAT 2824
PPPP P ++ ++S QA F R+P P + +L + +A+
Sbjct: 2251 PAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSP---PAPPPYKAPRLDEDGEAS 2307
Query: 2825 AATSMRFAMSARFPSTPGPELG---RQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELR 2881
T P PG G R + +P L PGEP G P E
Sbjct: 2308 EDT----------PQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPA-GEESPGPLQERS 2356
Query: 2882 HNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPE 2941
+ P P GPPQ P + P L E + SG PP+P+
Sbjct: 2357 PLL---------PLPEDGPPQVP------DGPPDLLLES-QWHHYSGEASSSEEEPPSPD 2400
Query: 2942 LNNSLHPTPHTKGPTL 2957
+ + P GP L
Sbjct: 2401 --DKENQAPKRTGPHL 2414
Score = 42.7 bits (99), Expect = 0.010
Identities = 32/97 (32%), Positives = 41/97 (42%), Gaps = 18/97 (18%)
Query: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSP-----ASPPTEPLVELPT 4938
P P P + S T+++ + APP PSPLAP P ASPP L T
Sbjct: 1884 PLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRR--PSPLAPRPPPSRWASPP------LKT 1935
Query: 4939 EPLAEPPVPSPLPLASSPESAR-----PKPRARPPEE 4970
P P P+ + A +P S P P PPE+
Sbjct: 1936 SPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPED 1972
Score = 42.4 bits (98), Expect = 0.013
Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 12/105 (11%)
Query: 4880 KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTE 4939
K+E+ P PP L S PPP P PPP P++P P P P + E
Sbjct: 396 KEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPP-PVSPPPLPSPPPPPAQEEQE 454
Query: 4940 PLAEPPVPSPL-------PLASSPESARPKPRARPPEEGEDSRPP 4977
P VP+ PL S + R RA P E + PP
Sbjct: 455 ESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGP----EGTSPP 495
Score = 41.6 bits (96), Expect = 0.022
Identities = 101/457 (22%), Positives = 145/457 (31%), Gaps = 98/457 (21%)
Query: 2548 KPPVPQPGLPPPHGINS---HFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGES 2604
KP P P +P H S GPGP G P+ + G G G
Sbjct: 249 KPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGR------------GGRGRG 296
Query: 2605 YGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGIT-SPVEKREDPGTGMGSSLATAELPG 2663
G G LP++ S+ + + + G G G + +
Sbjct: 297 RG----------------GGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVP 340
Query: 2664 TQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAE 2723
+ G +KQ Q+ E +++ +++ +EKE A A E
Sbjct: 341 QRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVA------------E 388
Query: 2724 PSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSS 2783
PA E+ P T PP+ P L P S L PPPP
Sbjct: 389 EMMPAAEKEEAKLPPPPLT---------PPAPSPPPPLPPPSTSPPPPLCPPPPPPV--- 436
Query: 2784 MDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGP 2843
P P P Q++Q AT R R P TP
Sbjct: 437 ----------------SPPPLPSPPPPPAQEEQEESPPPVVPATCSR--KRGRPPLTPSQ 478
Query: 2844 ELGRQALGSPLAGISTRLPGP-----GEPVPGPAGPAQFIELRHNVQKGLGPG------- 2891
R+A + G S P P G P P + N+++ + P
Sbjct: 479 RAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSR 538
Query: 2892 --GTP--FPGQGPPQRPR--FYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAP----PAPE 2941
TP F + PP+ P+ PV P +P + A PP+ P+ P P PE
Sbjct: 539 VIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPE 598
Query: 2942 LNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNP 2978
S+ P + +L EL PP+ P+P
Sbjct: 599 KRRSILREPTFRWTSLTR--ELPPPPPAPPPPPAPSP 633
Score = 41.6 bits (96), Expect = 0.022
Identities = 29/74 (39%), Positives = 37/74 (50%), Gaps = 7/74 (9%)
Query: 4906 LSAPPPEEPSPPPSPL-APSPA-SPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
+ A EE PP PL P+P+ PP P P PL PP P P++ P + P P
Sbjct: 391 MPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPP---PVSPPPLPSPPPP 447
Query: 4964 RARPPEEGEDSRPP 4977
A+ EE E+S PP
Sbjct: 448 PAQ--EEQEESPPP 459
Score = 41.2 bits (95), Expect = 0.029
Identities = 37/160 (23%), Positives = 55/160 (34%), Gaps = 26/160 (16%)
Query: 4314 PQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKG 4373
P K ++LP P P + PP P + P P PPP VSP
Sbjct: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPL---------- 441
Query: 4374 LGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKR 4433
P PP E Q+ +VP + G+ SQ + ++ R P
Sbjct: 442 --PSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGP---------- 489
Query: 4434 EANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQ 4473
E P P T+ GP ++ + + KN++
Sbjct: 490 EGTSPPTPTPSTAT----GGPPEDSPTVAPKSTTFLKNIR 525
Score = 41.2 bits (95), Expect = 0.029
Identities = 103/447 (23%), Positives = 149/447 (33%), Gaps = 79/447 (17%)
Query: 4000 GMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSE----ATEGPSTHQGGPLAIGTTP 4055
G+ PL SP +L + G P S A P + P + T+P
Sbjct: 1879 GVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASP-PLKTSP 1937
Query: 4056 ESMATEPGEVKPSLSGDS-QLLLVQPQPQPQP-----------------SSLQLQPPLRL 4097
+ P V +L+ S +L P P P P S+ L L
Sbjct: 1938 QLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASL 1997
Query: 4098 PGQQQQQVSLLHT-AGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQ 4156
G + Q ++ A G SHG G S E+S + P V++ PG P
Sbjct: 1998 LGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFP-VTVVSAPGLAPSAT--PG 2054
Query: 4157 QPMLERPMQNNTGP-------QPPKPGPVLQSGQGLPGVGIMPTVGQ-------LRAQLQ 4202
P +E+ + G Q P+ SG G+ G++ G L +++
Sbjct: 2055 APRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIV 2114
Query: 4203 GVLAKN---PQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGC 4259
+ KN P P+++ A + Q SQ + +P +P + L G G
Sbjct: 2115 DFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPA--DPTRTFAWLPGAPGV 2172
Query: 4260 QP-QLGGFPGPQTGPLQEL--------------GAG---PRPQGPPRLPA---------- 4291
+ LG P P ++ G G P P P LP
Sbjct: 2173 RVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSW 2232
Query: 4292 --PPGAL-STGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQG 4348
PPG L PV+G V P PPP P S P+ + + T G P
Sbjct: 2233 TLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAP 2292
Query: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLG 4375
P + P R+ DT GLG
Sbjct: 2293 PPYKAP--RLDEDGEASEDTPQVPGLG 2317
Score = 37.4 bits (85), Expect = 0.42
Identities = 48/165 (29%), Positives = 65/165 (39%), Gaps = 38/165 (23%)
Query: 4816 EVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDI 4875
E L P P G++P +G P + A LPG + +
Sbjct: 2134 ESLPPAPPLANGSQPSQGLTASPADPTRTF----------------AWLPG---APGVRV 2174
Query: 4876 LSLLKQESPAPEPPTQHSYTYNVSN----LDVRQLSA-----PPPEEPSPPP--SPLAPS 4924
LSL PAPEPP + + N + V+ PP ++P PP SP AP+
Sbjct: 2175 LSL----GPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPT 2230
Query: 4925 PASPPTEPLV-ELPTEPL---AEPPVPSPLPLASSPESARPKPRA 4965
+ P PL+ LP + A PP P PL L S A P +A
Sbjct: 2231 SWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQA 2275
Score = 37.0 bits (84), Expect = 0.55
Identities = 36/105 (34%), Positives = 42/105 (40%), Gaps = 25/105 (23%)
Query: 4269 PQTGPLQELGAGPRPQ--------------GPPRLPAPPGALSTGPVLGPVHPTPPPS-- 4312
P PL + GP P G P PAPP S P P+ P PPPS
Sbjct: 1872 PSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPP-RRSRRP--SPLAPRPPPSRW 1928
Query: 4313 -SPQEPKRPS-QLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPP 4355
SP P ++P P+S + L PT G P GP PPP
Sbjct: 1929 ASPPLKTSPQLRVPPPTSVV---TALTPT-SGELAPPGPAPSPPP 1969
Score = 36.6 bits (83), Expect = 0.71
Identities = 78/356 (21%), Positives = 127/356 (35%), Gaps = 85/356 (23%)
Query: 3071 RLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPS 3130
R+V++ E LLR + P P R A + S PR + P GR
Sbjct: 188 RMVQALTE------LLRRAQ-APQAPRSR---ACEPSTPRRSRGRPP--------GRPAG 229
Query: 3131 PC----------QFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTA 3180
PC + + PK EP P + P + GS + G GP +
Sbjct: 230 PCRRKQQAVVVAEAAVTIPKPEPPPP-------VVPVKHQTGSWKCKEGPGPGPGTPRRG 282
Query: 3181 EKASFGATGGPPAHLLTPSPLSGPGGS--------SLLEKFELESGALTLPGGPAASGDE 3232
++S G GG G GG S +K ++ +L L G E
Sbjct: 283 GQSSRGGRGGRGR---------GRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHE 333
Query: 3233 LD-------KMESSLVASELPLLIEDLL---EHEKKELQKKQQ---------LSAQLQPA 3273
++ S S E L E EKKE ++K + ++ ++ PA
Sbjct: 334 ESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPA 393
Query: 3274 QQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQ 3333
++++ + L+ P P+ LP +SP L P + P +P+
Sbjct: 394 AEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPP---------LCPPPPPPVSPPPLPSP 444
Query: 3334 PPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQK-PMGTMPPS 3388
PP A +++ +V + G+ L P Q ++ ++ P GT PP+
Sbjct: 445 PPPPAQEEQEESPPPVVP----ATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPT 496
Score = 36.2 bits (82), Expect = 0.93
Identities = 36/117 (30%), Positives = 42/117 (35%), Gaps = 23/117 (19%)
Query: 4273 PLQELGAGPRPQGPPRLPAPPGALSTGP---VLGPVHPTPPPSSPQEPKRPSQLP----- 4324
PL P P PP +PP L P V P P+PPP QE + S P
Sbjct: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPAT 464
Query: 4325 ----------SPSSQLPTEAQL---PPTHPGTPKPQGPTLEPPPGRVSPAAAQLADT 4368
+PS + EA T P TP P T PP SP A + T
Sbjct: 465 CSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPED--SPTVAPKSTT 519
Score = 36.2 bits (82), Expect = 0.93
Identities = 34/107 (31%), Positives = 42/107 (39%), Gaps = 25/107 (23%)
Query: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEP----SPPPSPLAPSPA-------SPPTEPLV 4934
P P +HS + NLD PP P +PPP+P + S A SP PL
Sbjct: 1829 PGAPERHS---PIQNLD-------PPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLG 1878
Query: 4935 ELPTEPLAEPPVPSPL----PLASSPESARPKPRARPPEEGEDSRPP 4977
+ PL P PS L P P+ P R+R P PP
Sbjct: 1879 GVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPP 1925
Score = 35.4 bits (80), Expect = 1.6
Identities = 57/234 (24%), Positives = 88/234 (37%), Gaps = 32/234 (13%)
Query: 3091 PGPLGPEERPPPAADASEPRLASVLPEVKP-----KVEEGGRHPSPCQFTIATPKVEPAP 3145
P P P P PA + P L P+ P K+ E P P A P+ EP P
Sbjct: 626 PPPPAPSPPPAPATSSRRPLLLRA-PQFTPSEAHLKIYESVLTPPPLGAPEA-PEPEPPP 683
Query: 3146 AANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPG 3205
A +S +P +G R + F+ T KA G P L+ P +
Sbjct: 684 ADDSPA---EPEPRAVG-RTNHLSLPRFAPVVTTPVKAEVSPHGAPA---LSNGPQTQAQ 736
Query: 3206 GSSLLEKFELESGALTLPGG-----PAASGDELDKMESSLVASELPLLIEDLLEHEKKEL 3260
L+ + + LP P S ++ +E + +A L + + E+K
Sbjct: 737 LLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGV---EEKMF 793
Query: 3261 QKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLS 3314
++ QL QQQQQ+ S+ +PG G +AG+ +Q+S
Sbjct: 794 SLLKRAKVQLFKIDQQQQQKVAASMPLSPG----------GQMEEVAGAVKQIS 837
Score = 34.3 bits (77), Expect = 3.5
Identities = 80/366 (21%), Positives = 115/366 (31%), Gaps = 61/366 (16%)
Query: 4010 SSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSL 4069
S PG + +L ++ + SE + + GGP G P + P +
Sbjct: 2086 SGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANG 2145
Query: 4070 SGDSQLLLVQPQPQ----------PQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQL 4119
S SQ L P P L L P P ++ L++ G Q+
Sbjct: 2146 SQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLG-----QV 2200
Query: 4120 GSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGP-- 4177
+ E VP + QP + P + T L P + P+ P PP P P
Sbjct: 2201 FVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPL 2260
Query: 4178 --VLQSGQGLPGVGIMPTVGQLRAQLQGVLAKN-PQLRHLSPQQQQQLQALLMQRQLQQS 4234
VL SG P Q + K SP +A + + S
Sbjct: 2261 TLVLSSGPASP-------------PRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEAS 2307
Query: 4235 QAVRQTPPYQEPG-----TQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRL 4289
+ Q P G +T ++G+L PG G E GP + P L
Sbjct: 2308 EDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDR-----PGEPAG---EESPGPLQERSPLL 2359
Query: 4290 PAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPT----HPGTPK 4345
P P P P P + SQ S + + + PP+ PK
Sbjct: 2360 PLPEDG-----------PPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPK 2408
Query: 4346 PQGPTL 4351
GP L
Sbjct: 2409 RTGPHL 2414
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 177 bits (448), Expect = 3e-43
Identities = 98/290 (33%), Positives = 154/290 (53%), Gaps = 16/290 (5%)
Query: 5259 SPQAVWNRIIEPVAAMRKEADMLRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYL 5318
S + W + + V R A + +L + G + G+ AV+ + E L G + C+NY
Sbjct: 3685 SIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYK 3744
Query: 5319 FRYGRHPLMELPLMINPTGCARSEPK-----------ILTHYKRPHTLNSTSMSKAYQST 5367
FR+ + P +NP G AR+E + + +++P N +
Sbjct: 3745 FRFHKPEEANEP-PLNPHGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQL 3803
Query: 5368 FTGETNTPYSKQFVHSKSSQYRRLRTEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEYI 5427
+ T ++R L+ K V + RS I G GL+ ++++ MVIEY
Sbjct: 3804 KSARRATSMDLPM----PMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYA 3859
Query: 5428 GTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVT 5487
G +IR+ ++REK Y+ + G YMFRI++ V+DAT+ G AR+INHSC PNC + V+
Sbjct: 3860 GNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVIN 3919
Query: 5488 FDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN 5537
D + I+I + R+I +GEELTYDY+F ED +K+PC+CGA CRK++N
Sbjct: 3920 IDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFLN 3969
Score = 147 bits (371), Expect = 3e-34
Identities = 78/219 (35%), Positives = 115/219 (52%), Gaps = 10/219 (4%)
Query: 5020 LRPDKVPRDMRRCCFCHEEGDGATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMN 5079
L P D R+C C GD + + RLL + + W H+NCALWS EV+E G+L N
Sbjct: 1861 LNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKN 1920
Query: 5080 VEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPMHK-- 5137
V +A+ RG +C CQ+ GAT C C + YHF C+ C+F DK + C H+
Sbjct: 1921 VHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDL 1980
Query: 5138 IKGPCEQELSSFAVFRRVYIERDEVKQIASIIQ--RGERLHMFRVGGLVFHAIGQLLPHQ 5195
IKG E + F VFRRV+++ + + + E +HM +G + +G L +
Sbjct: 1981 IKGEVVPE-NGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMM-IGSMTIDCLGIL--ND 2036
Query: 5196 MADFHSATALYPVGYEATRIYWSLRTNNRRCCYRCSIGE 5234
++D L+P+GY+ +R+YWS +RC Y C I E
Sbjct: 2037 LSDCED--KLFPIGYQCSRVYWSTTDARKRCVYTCKIVE 2073
Score = 110 bits (275), Expect = 4e-23
Identities = 61/197 (30%), Positives = 95/197 (48%), Gaps = 24/197 (12%)
Query: 1379 MCVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVM-LLKGWRCVECIVCEVCGQAS 1437
+C +C S G + C C + +H +C+ + L+ W C C C VCG+
Sbjct: 1433 VCFLCASSGHV---EFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQH 1489
Query: 1438 DPSRLLL-CDDCDISYHTYCLDPPLLTVP---KGGWKCKWCVSCMQCGAASPG--FHCEW 1491
++ LL C+ C SYH CL P T P K W C CV C CG+ +PG + +W
Sbjct: 1490 QATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQW 1549
Query: 1492 QNSYTHCGPCASLVT----CPICHAPYVEEDL---LIQCRHCERWMHAGCESLFTEDDVE 1544
+ ++ C CA L CP+C Y ++D ++QC C+RW+H+ CE+L D++
Sbjct: 1550 SHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENL--SDEMY 1607
Query: 1545 QAADE-----GFDCVSC 1556
+ + CV+C
Sbjct: 1608 EILSNLPESVAYTCVNC 1624
Score = 74.7 bits (182), Expect = 2e-12
Identities = 94/447 (21%), Positives = 157/447 (35%), Gaps = 78/447 (17%)
Query: 229 CAVCEGPGELCDLFFCTSCGHHYHGACLDT--ALTARKRAGWQCPECKVCQACRKPGNDS 286
C +C G + + +C C +H CL+ + W C CK C C + +
Sbjct: 1434 CFLCASSGHV-EFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQAT 1492
Query: 287 KMLV-CETCDKGYHTFCLKPPMEELPAHS---WKCKACRVCRACGAGSAELNPNSEWFEN 342
K L+ C C YH CL P P W C C C++CG+ + +++W +
Sbjct: 1493 KQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHD 1552
Query: 343 YSLCHRCHK--AQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDE---------------P 385
+SLCH C K A+G P+C + + ++ +
Sbjct: 1553 FSLCHDCAKLFAKG---------NFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLS 1603
Query: 386 DALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEE-------- 437
D +Y P+ T + E P + + + L+ L A LN
Sbjct: 1604 DEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRY 1663
Query: 438 MPLLPPPE---ESPLSPPPEESPTSP-PPEASRLSPPPEELP---------------ASP 478
PP+ E+ S P SP P PP + +S ++ P S
Sbjct: 1664 RQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSV 1723
Query: 479 LPEALHLSRPLEESPLSP--PPEESPLSPPPES---------SPFSPLEESPLSPPEESP 527
L + + + ++ + S PE + +S P+ +++S P +
Sbjct: 1724 LEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVS 1783
Query: 528 PSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE 587
+ + PP ++E E T PP ++ P P+ P
Sbjct: 1784 SNSGMLPNAVLPPSLDHNYAQWQER-----EENSHTEQPPLMKKIIPAPKPKGPGEPDSP 1838
Query: 588 SPMSPP-PEASRLFPPFEESP-LSPPP 612
+P+ PP P E+SP L+PPP
Sbjct: 1839 TPLHPPTPPILSTDRSREDSPELNPPP 1865
Score = 54.3 bits (129), Expect = 3e-06
Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 3/88 (3%)
Query: 133 GGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGASIPCRSPGCPRL 192
G + W H CA WSA V+ + L V A+ G RC C + GA++ C C
Sbjct: 1894 GQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSN 1953
Query: 193 YHFPCATASGS-FLSMKTLQLLCPEHSE 219
YHF C+ A FL K ++ C H +
Sbjct: 1954 YHFMCSRAKNCVFLDDK--KVYCQRHRD 1979
Score = 53.1 bits (126), Expect = 7e-06
Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 2/140 (1%)
Query: 508 ESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP 567
ESS + +S P + PA + S PP P+ EE +S P E + P
Sbjct: 1230 ESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTP 1289
Query: 568 EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLS 627
+ + S + + PP+ PP + P E PPP ES P +
Sbjct: 1290 ASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPES--GPEQSKQKKV 1347
Query: 628 PPPEDSPMSPPPEESPMSPP 647
P P+ P+E PP
Sbjct: 1348 APRPSIPVKQKPKEKEKPPP 1367
Score = 51.6 bits (122), Expect = 2e-05
Identities = 37/137 (27%), Positives = 52/137 (37%), Gaps = 13/137 (9%)
Query: 566 PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASR 625
P ++R P P++S PPP + P+ E + P ES + P S
Sbjct: 1244 PTPSAREDPAPKKSSSEPPPRK-PVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPA 1302
Query: 626 LSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPE 685
L PP+ PP +E P + P E + P PPPE P ++ +P P
Sbjct: 1303 LVIPPQPPTTGPPRKEVPKTTPSEPKKKQP--------PPPESGP--EQSKQKKVAPRPS 1352
Query: 686 ASRLSPPPEDSPTSPPP 702
P E PPP
Sbjct: 1353 IPVKQKPKEKE--KPPP 1367
Score = 50.4 bits (119), Expect = 5e-05
Identities = 81/379 (21%), Positives = 139/379 (36%), Gaps = 53/379 (13%)
Query: 2371 PGSYTDPYAQPPLTPRPQPPPPESCCA------LPPRSLPSDPFSRVPASPQSQSSSQSP 2424
P T PPL P P P S + +PP + PF +P Q +S
Sbjct: 553 PQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPM-QGKRKSI 611
Query: 2425 LTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSL 2484
L + S P++ S Y++ R P +PP P +V F +G
Sbjct: 612 LREPTFRWTSLKHSRSEPQYFSSAKYAK---EGLIRKPIFDNFRPPPLTPEDVGFASGFS 668
Query: 2485 AHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGE 2544
A + + + L +G ++H + P + P F TPS ++V
Sbjct: 669 ASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRF-----------TPSEAHSRIFESVTL 717
Query: 2545 PSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLG----PSSGS 2600
PS + + P +P+S ++++ T + S S L PSS S
Sbjct: 718 PSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVS 777
Query: 2601 TGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAE 2660
+ S +SPL ++ P + + SH +Q SG ++ +R T + ++
Sbjct: 778 SSLSISVSPLATSALNP------TFTFPSHSLTQ-SGESAEKNQRPRKQTSAPAEPFSSS 830
Query: 2661 LPGTQDPGMSGLSQTE---------------------LEKQRQRQRLRELLIRQQIQRNT 2699
P P + SQTE +EK + R+R RE + +
Sbjct: 831 SPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRK 890
Query: 2700 LRQEKETAAAAAGAVGPPG 2718
+++K + ++ A+ P G
Sbjct: 891 EKRKKGSEIQSSSALYPVG 909
Score = 50.1 bits (118), Expect = 6e-05
Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 16/128 (12%)
Query: 443 PPEESPLSPPPEESPTSPPP--------EASRLSPPPEELPASPLPEALHLSRPLEESPL 494
P + P P++S + PPP E +S P E + P + S+ + + L
Sbjct: 1244 PTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPAL 1303
Query: 495 SPPPEESPLSPP----PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE 550
PP+ PP P+++P P ++ P PP ES P + + ++P P P E
Sbjct: 1304 VIPPQPPTTGPPRKEVPKTTPSEPKKKQP--PPPESGPEQSKQKKVAPRPSIPVKQKPKE 1361
Query: 551 ESPLSPPP 558
+ PPP
Sbjct: 1362 KE--KPPP 1367
Score = 49.3 bits (116), Expect = 1e-04
Identities = 37/134 (27%), Positives = 48/134 (35%), Gaps = 9/134 (6%)
Query: 487 RPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLS 546
+P + P P++S PPP EE +S P P S TP S
Sbjct: 1243 KPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAP--GPESKQATTPASRKSSKQVSQ 1300
Query: 547 PPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEES 606
P L PP+ T PP + + P E PPP ES P + P
Sbjct: 1301 PA-----LVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPES--GPEQSKQKKVAPRPSI 1353
Query: 607 PLSPPPEESPLSPP 620
P+ P+E PP
Sbjct: 1354 PVKQKPKEKEKPPP 1367
Score = 48.5 bits (114), Expect = 2e-04
Identities = 35/128 (27%), Positives = 49/128 (38%), Gaps = 5/128 (3%)
Query: 557 PPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPP-PEASRLFPPFEESPLSPPPEES 615
P P P+ S PPP + P+ EE +S P PE+ + P S +
Sbjct: 1244 PTPSAREDPAPKKSSSEPPPRK-PVEEKSEEGNVSAPGPESKQATTPASRKS-SKQVSQP 1301
Query: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
L PP+ PP ++ P + P E PPP S P + P P+ P
Sbjct: 1302 ALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPES--GPEQSKQKKVAPRPSIPVKQKP 1359
Query: 676 EESPTSPP 683
+E PP
Sbjct: 1360 KEKEKPPP 1367
Score = 48.5 bits (114), Expect = 2e-04
Identities = 33/123 (26%), Positives = 51/123 (41%), Gaps = 6/123 (4%)
Query: 611 PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670
P + P P+ S PPP P+ EE +S P S+ + P + S +
Sbjct: 1244 PTPSAREDPAPKKSSSEPPPR-KPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPA 1302
Query: 671 LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730
L PP+ T PP + + P E PPP +S PE S + P +P+ +
Sbjct: 1303 LVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPES----GPEQSKQK-KVAPRPSIPVKQ 1357
Query: 731 EPQ 733
+P+
Sbjct: 1358 KPK 1360
Score = 45.8 bits (107), Expect = 0.001
Identities = 92/373 (24%), Positives = 136/373 (36%), Gaps = 41/373 (10%)
Query: 426 LEPQLEAPLNEEMPLLPPPE-ESPLSPPPEESPTSPPPEA----SRLSPPPEELPASPLP 480
++ ++ +EE+ +LP ++P PP SP E+ SR E S
Sbjct: 484 VDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTT 543
Query: 481 EALHL--SRPLEESPLSPPPEESPLSPPPESSPFSPLEE-----SPLSPPEESPPSPALE 533
+ L S P +++ SPPP L+PPP P S + + P + P SP PA
Sbjct: 544 KKLSTLQSAPQQQTSSSPPPPL--LTPPPPLQPASSISDHTPWLMPPTIPLASPFLPAST 601
Query: 534 TPLSPPPEASPLSPPFEESPLS---PPPEELPTSPPPEASRLSPPPEESPMSPP--PEES 588
P+ ++ P F + L P+ ++ + + P ++ PP PE+
Sbjct: 602 APMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDV 661
Query: 589 PMSPPPEAS------RLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642
+ AS RLF P + SPL P R +P S + ES
Sbjct: 662 GFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAP---RFTPSEAHSRIF----ES 714
Query: 643 PMSPPPEVSR-LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPP 701
P S S V +R SP+ P S + RLS E SP +PP
Sbjct: 715 VTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLS-SSELSPLTPP 773
Query: 702 PEDSPASPPPEDSLMSLPLEESPLLPLPEEP--QLCPRSEGPHLSPRPEEPHLSPRPEEP 759
S + S+ PL S L P P L E + RP + +P
Sbjct: 774 SSVSSSL-----SISVSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFS 828
Query: 760 HLSPQAEEPHLSP 772
SP P +P
Sbjct: 829 SSSPTPLFPWFTP 841
Score = 45.4 bits (106), Expect = 0.002
Identities = 60/250 (24%), Positives = 96/250 (38%), Gaps = 29/250 (11%)
Query: 541 EASPLSPPFEESPLSPPPE-ELPTSPPPEASRLSPPPEESPMSPPPEE-----SPMSPPP 594
+A PL+PP + P+ P + P PP + R S + P PE+ + + P
Sbjct: 1121 DAEPLAPPIK--PIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPK 1178
Query: 595 EASRLFPPF-----EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPE 649
R + L P ++ L +A + + +ES +
Sbjct: 1179 FGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVV 1238
Query: 650 VSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP 709
S P P +R P P++S PPP + P E S E + ++P PE A+
Sbjct: 1239 DSSQKPTPS-AREDPAPKKSSSEPPPRK----PVEEKSE-----EGNVSAPGPESKQATT 1288
Query: 710 PPEDSLMSLPLEESPLLPLPEEPQLC--PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEE 767
P S S P L +P +P PR E P +P + P PE Q+++
Sbjct: 1289 PA--SRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESG--PEQSKQ 1344
Query: 768 PHLSPQPEEP 777
++P+P P
Sbjct: 1345 KKVAPRPSIP 1354
Score = 45.4 bits (106), Expect = 0.002
Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 19/149 (12%)
Query: 577 EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMS 636
+ES + +S P P A P P++S PPP E + +
Sbjct: 1229 KESSVVKNVVDSSQKPTPSARE----------DPAPKKSSSEPPPRKPVEEKSEEGNVSA 1278
Query: 637 PPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS-PPPEESPTSPPPEASRLSPPPED 695
P PE + P SR S V P + P + PP +E P + P E + PPP +
Sbjct: 1279 PGPESKQATTP--ASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPE 1336
Query: 696 SPTSPPPEDSPASPPPEDSLMSLPLEESP 724
S + A P S+P+++ P
Sbjct: 1337 SGPEQSKQKKVAPRP------SIPVKQKP 1359
Score = 43.1 bits (100), Expect = 0.008
Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 5/103 (4%)
Query: 837 SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLG 896
S++P S R + + E PP P EK E P PE P S S +
Sbjct: 1241 SQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKS-SKQVS 1299
Query: 897 EPALSEPGEPPLS-PLPEELPLSPSGEPSLSPQLMPPDPLPPP 938
+PAL P +PP + P +E+P + EP + PP P P
Sbjct: 1300 QPALVIPPQPPTTGPPRKEVPKTTPSEPK---KKQPPPPESGP 1339
Score = 40.8 bits (94), Expect = 0.038
Identities = 41/177 (23%), Positives = 62/177 (35%), Gaps = 23/177 (12%)
Query: 454 EESPTSPPPEASRLSPPPEELPASPL--------PEALHLSRPLEESPLSPPPEESPLSP 505
E+ PP + +RL P ++P + H S+ +S S P +
Sbjct: 430 EDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTD 489
Query: 506 PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPL----------- 554
S L E PE PP P ++P + + E
Sbjct: 490 SQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTL 549
Query: 555 -SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSP 610
S P ++ +SPPP L+PPP P S + +P PP L PF + +P
Sbjct: 550 QSAPQQQTSSSPPPPL--LTPPPPLQPASSISDHTPWLMPPTIP-LASPFLPASTAP 603
Score = 40.4 bits (93), Expect = 0.049
Identities = 55/254 (21%), Positives = 85/254 (33%), Gaps = 47/254 (18%)
Query: 263 RKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACRV 322
R R QCP C+V + C G T CL P + + K + C++
Sbjct: 1151 RSRRCGQCPGCQVPEDC-----------------GVCTNCLDKP--KFGGRNIKKQCCKM 1191
Query: 323 CRACGAGSAELNPNSEWFENYSLCHRCHKA-----QGGQTIRSVAEQHTPVCSRFSPPEP 377
R C N +W + + + KA + +T + + V
Sbjct: 1192 -RKC--------QNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQ 1242
Query: 378 GDTPTDEPDALYVACQGQPKGGHVTSMQPKE-----PGPLQCEAKPLGKAGVQLEPQLEA 432
TP+ D +P + +E PGP +A A + Q+
Sbjct: 1243 KPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATT--PASRKSSKQVSQ 1300
Query: 433 PLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES 492
P L+ PP+ PP +E P + P E + PPP E + P P
Sbjct: 1301 P-----ALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPE--SGPEQSKQKKVAPRPSI 1353
Query: 493 PLSPPPEESPLSPP 506
P+ P+E PP
Sbjct: 1354 PVKQKPKEKEKPPP 1367
Score = 39.3 bits (90), Expect = 0.11
Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 13/134 (9%)
Query: 4882 ESPAPEPPTQHSYTYNVS--NLDVRQLSAPPPEEPSPPPS-PLAPSPASPPTE--PLVEL 4936
E P +P + S NVS + +Q + P + S S P P PPT P E+
Sbjct: 1260 EPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEV 1319
Query: 4937 PTEPLAEPPVPSPLPLASSPESARPKPRARPP------EEGEDSRPPRLKKWKGVRWKRL 4990
P +EP P P S PE ++ K A P + E +PP + K + L
Sbjct: 1320 PKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENA--GTL 1377
Query: 4991 RLLLTIQKGSGRQE 5004
+L T+ G+ ++
Sbjct: 1378 NILSTLSNGNSSKQ 1391
Score = 38.5 bits (88), Expect = 0.19
Identities = 90/389 (23%), Positives = 133/389 (34%), Gaps = 70/389 (17%)
Query: 4147 SMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLA 4206
S T L P P + Q PGP + + T L+ + ++
Sbjct: 3026 SSTPGLQVPVSPTVPIQNQKYVPNSTDSPGP-----SQISNAAVQTTPPHLKPATEKLIV 3080
Query: 4207 KNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQT-SPLQGLL----GCQP 4261
N +++ P Q + +++Q + +V TP E T P+ G L G P
Sbjct: 3081 VN---QNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNP 3137
Query: 4262 QLGG----FPGPQTG--------PLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTP 4309
L FP G L A + PP + PP L G V P P
Sbjct: 3138 SLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIG-----VQPPP 3192
Query: 4310 PP-----SSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQ 4364
P S Q + + +PSS L + P + T K + P ++P+
Sbjct: 3193 DPQLLVSESSQRTDLSTTVATPSSGL---KKRPISRLQTRKNKKLAPSSTPSNIAPSDVV 3249
Query: 4365 LADTLFSKGLGPWDPPDNLAETQKPEQSSLVP-GHLDQVNGQVVPEASQLSIKQEPREEP 4423
TL N +Q P SL+ G L+ + + VP + S EP
Sbjct: 3250 SNMTLI-----------NFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEP 3298
Query: 4424 CALGAQSVKREANGEPIGAPGTS------NHLLLAGPRSEAGHLLLQKLLRAKNVQLSTG 4477
L QSV G A GTS +HL S +G +L ++Q +T
Sbjct: 3299 APLLPQSV----GGTAATAAGTSTISQDTSHLTSG---SVSGLASSSSVLNVVSMQTTTT 3351
Query: 4478 RGSEGLRAEINGHIDSKLAGLEQKLQGTP 4506
S A + GH+ +L GTP
Sbjct: 3352 PTSS---ASVPGHVTL----TNPRLLGTP 3373
Score = 38.1 bits (87), Expect = 0.24
Identities = 38/129 (29%), Positives = 53/129 (41%), Gaps = 18/129 (13%)
Query: 909 SPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSD 968
S EE+ + P E S +P++ PP LP SP + E FG++
Sbjct: 490 SQASEEIQVLPE-ERSDTPEVHPP--LPISQSPE-NESNDRRSRRYSVSERSFGSRTTKK 545
Query: 969 PESPLAAPILETPISPPPEANCTDPEPVPPMILPP---SPGSPVGPASPILMEPLPPQCS 1025
+ +AP +T SPP PP++ PP P S + +P LM P P S
Sbjct: 546 LSTLQSAPQQQTSSSPP-----------PPLLTPPPPLQPASSISDHTPWLMPPTIPLAS 594
Query: 1026 PLLQHSLVP 1034
P L S P
Sbjct: 595 PFLPASTAP 603
Score = 38.1 bits (87), Expect = 0.24
Identities = 66/313 (21%), Positives = 116/313 (37%), Gaps = 33/313 (10%)
Query: 656 LPVVSRLSPPPEESPLSPP--PEESPTSPPPEASRLSPPPEDSPTSPPPED-SPASPPPE 712
+P +S L E LS ++S + +A L+PP + P P + +P PP +
Sbjct: 1090 MPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIK--PIKPVTRNKAPQEPPVK 1147
Query: 713 DSLMSLPLEESPLLPLPEEPQLC------PRSEGPHLSPR----PEEPHLSPRPEEPHLS 762
S + P +PE+ +C P+ G ++ + + +L P + +L
Sbjct: 1148 KGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQ 1207
Query: 763 PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEP 822
QA+ + + +E + P P P ++ P P +P
Sbjct: 1208 KQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSARE-DPAPKKSSSEPPPRKP 1266
Query: 823 CLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPL 882
+ + EE ++S E + P S ++ +P L PP+ P P +E+P
Sbjct: 1267 -VEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVI----PPQPPTTGPPRKEVPK 1321
Query: 883 FPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD-PLPPPLSP 941
P EP +P PP S + + PS+ + P + PPP++
Sbjct: 1322 TTP----------SEPKKKQP-PPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNK 1370
Query: 942 IITAAAPPALSPL 954
A LS L
Sbjct: 1371 QENAGTLNILSTL 1383
Score = 37.7 bits (86), Expect = 0.32
Identities = 71/295 (24%), Positives = 96/295 (32%), Gaps = 34/295 (11%)
Query: 424 VQLEPQLEAPLNEEMPLL-PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEA 482
+Q PQ + + PLL PPP P S + +P PP SP LPAS P
Sbjct: 549 LQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASP---FLPASTAPMQ 605
Query: 483 LHLSRPLEESPLSPPPEESPLSPPPESSP-------------FSPLEESPLSPPEE---- 525
L E + S P S F PL+P +
Sbjct: 606 GKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFAS 665
Query: 526 --SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP 583
S A L P + + SPL P P+ P + S
Sbjct: 666 GFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLP-SNRTSA 724
Query: 584 PPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP--PPEDSPMSPPPEE 641
S +S ++F P P SP S +S LSP PP S
Sbjct: 725 GTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISV 784
Query: 642 SPMSPPPEVSRLSP---LPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP 693
SP++ S L+P P S L+ E + + P + ++P S SP P
Sbjct: 785 SPLA----TSALNPTFTFPSHS-LTQSGESAEKNQRPRKQTSAPAEPFSSSSPTP 834
Score = 37.4 bits (85), Expect = 0.42
Identities = 33/119 (27%), Positives = 46/119 (38%), Gaps = 10/119 (8%)
Query: 431 EAPLNEEMPLLPPP--------EESPLSPPPEESPTSPPPEASRLSPPPEELPASPLP-E 481
E P ++ PPP EE +S P ES + P ASR S PA +P +
Sbjct: 1250 EDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTP-ASRKSSKQVSQPALVIPPQ 1308
Query: 482 ALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP 540
P +E P + P E PPP S ++ ++P P + PPP
Sbjct: 1309 PPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPP 1367
Score = 36.2 bits (82), Expect = 0.93
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVP-SPLPLASSPESARPKPRA 4965
S+PPP +PPP PL P+ + P + PT PLA P +P S P+ +S +P
Sbjct: 559 SSPPPPLLTPPP-PLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTF 617
Query: 4966 R 4966
R
Sbjct: 618 R 618
Score = 35.8 bits (81), Expect = 1.2
Identities = 126/575 (21%), Positives = 187/575 (32%), Gaps = 101/575 (17%)
Query: 2353 PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP----RPQPPPPESCCALPPRSLPSDPF 2408
PP ++ ++ D+ R S P Q P++P + Q P S + P + +
Sbjct: 3007 PPCGSVEQGHGNNQDLTRNSS--TPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAV 3064
Query: 2409 SRVPA--SPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPL 2466
P P ++ +PL P+ VT + Q S PS ++
Sbjct: 3065 QTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLG- 3123
Query: 2467 HKPPRPQPPEVAFKAGSLAHTSLGAGGFPAA----LPAGPAGELH---AKVPSGQPPNFV 2519
P + G FP+A LP LH A S PPN +
Sbjct: 3124 -----PMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFPPN-I 3177
Query: 2520 RSPGTGAFVGTPSPMRFTFPQA-VGEPSLKPPVPQPGLPPPHGI------------NSHF 2566
+P +G +G P PQ V E S + + P G+ N
Sbjct: 3178 SNPPSGLLIGVQPPPD---PQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKL 3234
Query: 2567 GPGPTLGK--PQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP------- 2617
P T P + NF PS P PS G S P+++
Sbjct: 3235 APSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIM 3294
Query: 2618 --PPAP-----DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSL--------ATAELP 2662
PAP G + G S S TS + G SS+ T
Sbjct: 3295 YFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTS 3354
Query: 2663 GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGA 2722
PG L+ L + LLI+ Q ++ + V P
Sbjct: 3355 SASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLGIQDQP---------VALP----- 3400
Query: 2723 EPSSPAFEQLSRGQTP-FAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPP--- 2778
PSS F QL QTP A SS+ LP ++ +G S +D+
Sbjct: 3401 -PSSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLL 3459
Query: 2779 ATPSSMDVNSRQLVGGS----QAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMS 2834
A+ + + + R L S F Q P S+ L+Q + ++ A+
Sbjct: 3460 ASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNK-------------ALSSAVQ 3506
Query: 2835 ARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVP 2869
A P++PG + G A S +PGP +P P
Sbjct: 3507 AS-PTSPGGSPSSPSSGQRSA--SPSVPGPTKPKP 3538
Score = 35.4 bits (80), Expect = 1.6
Identities = 36/125 (28%), Positives = 48/125 (38%), Gaps = 23/125 (18%)
Query: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAP-SPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
P VE +S + P QA P S S + +P P QPP T PP
Sbjct: 1262 PPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPP--QPPTTG---PPR 1316
Query: 2392 PESCCALPPRSLPSDPFSRVPASPQS--QSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDP 2449
E P++ PS+P + P P+S + S Q + PR P P Q P
Sbjct: 1317 KE-----VPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR----------PSIPVKQKPKE 1361
Query: 2450 YSRPP 2454
+PP
Sbjct: 1362 KEKPP 1366
Score = 35.0 bits (79), Expect = 2.1
Identities = 48/186 (25%), Positives = 68/186 (36%), Gaps = 42/186 (22%)
Query: 577 EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPED-SPM 635
E+ PP + + + P + P S S + ++SR S P D S
Sbjct: 430 EDEDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTD 489
Query: 636 SPPPEESPMSP-----PPEVSRLSPLPVVSRLSPPPEESP-------------------- 670
S EE + P PEV PLP+ SP E +
Sbjct: 490 SQASEEIQVLPEERSDTPEVH--PPLPISQ--SPENESNDRRSRRYSVSERSFGSRTTKK 545
Query: 671 ----LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726
S P +++ +SPPP L+PPP P S + +P PP ++PL SP L
Sbjct: 546 LSTLQSAPQQQTSSSPPPPL--LTPPPPLQPASSISDHTPWLMPP-----TIPL-ASPFL 597
Query: 727 PLPEEP 732
P P
Sbjct: 598 PASTAP 603
Score = 33.1 bits (74), Expect = 7.9
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 19/176 (10%)
Query: 4191 MPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQ----AVRQTPPYQEP 4246
MP+ L+ Q + V K + + + +++ ++ +++ + SQ + R+ P ++
Sbjct: 1200 MPSKAYLQKQAKAV--KKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKS 1257
Query: 4247 GTQTSPLQGLLGCQPQLG-GFPGPQ----TGPLQELGAGPRPQGPPRLPAPPGALSTGPV 4301
++ P + + + PGP+ T P + Q P L PP +TGP
Sbjct: 1258 SSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQ--PALVIPPQPPTTGPP 1315
Query: 4302 LGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP--TLEPPP 4355
V P ++P EPK+ P S ++ + P P Q P +PPP
Sbjct: 1316 RKEV----PKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPP 1367
Score = 33.1 bits (74), Expect = 7.9
Identities = 17/57 (29%), Positives = 23/57 (40%), Gaps = 8/57 (14%)
Query: 4300 PVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPG 4356
P++ + P P P P EP P+ L P+ P + P L PPPG
Sbjct: 1818 PLMKKIIPAPKPKGPGEPDSPTPLHPPTP--------PILSTDRSREDSPELNPPPG 1866
Score = 33.1 bits (74), Expect = 7.9
Identities = 69/314 (21%), Positives = 100/314 (31%), Gaps = 52/314 (16%)
Query: 4131 PHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQG-LPGVG 4189
P LL P + GS++ L+ Q L +Q+ PP G Q G P
Sbjct: 3367 PRLLGTPDI------GSISNLLIKASQQSLG--IQDQPVALPPSSGMFPQLGTSQTPSTA 3418
Query: 4190 IMPTVGQL----RAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245
+ + Q G+ A +P Q Q + LL +
Sbjct: 3419 AITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKT--------------- 3463
Query: 4246 PGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPV 4305
G+ Q L GPQ + P G + A A+ P
Sbjct: 3464 ---------GIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASP----- 3509
Query: 4306 HPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTP--KPQGPTLEPPPGRVSPAAA 4363
T P SP P + SPS PT+ + P K G + R S + A
Sbjct: 3510 --TSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEA 3567
Query: 4364 QLAD---TLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPR 4420
+ D T + G G +T EQSS Q GQV ++ + Q P
Sbjct: 3568 HIPDQETTSLTSGTGTPGAEAEQQDTASVEQSS--QKECGQPAGQVA-VLPEVQVTQNPA 3624
Query: 4421 EEPCALGAQSVKRE 4434
E + ++V+ E
Sbjct: 3625 NEQESAEPKTVEEE 3638
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 175 bits (443), Expect = 1e-42
Identities = 187/698 (26%), Positives = 285/698 (40%), Gaps = 101/698 (14%)
Query: 437 EMPLLPP--PEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL 494
E P PP PE S PP++ PT P PP ++P P + + E P
Sbjct: 10434 EKPKAPPKGPEISEKIIPPKKPPTKVVPRKE----PPAKVPEVPKKIVVEEKVRVPEEPR 10489
Query: 495 SPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPL 554
PP + + PP E P + P PE PP PEA P ++ P+
Sbjct: 10490 VPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPK---------VPEAPKEVVPEKKVPV 10540
Query: 555 SPPPE-ELPTSPPPEASRLSPPPEESPMS-PPPEESPMSPPPEASRLFPPFEESPLSPP- 611
PP + E+P + PE + + P ++ P + PP ESP PEA + P ++ P +PP
Sbjct: 10541 PPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPK 10600
Query: 612 -PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670
PE +P+ PEA + P + P+ PP + P PP +V P V +++ P ++ P
Sbjct: 10601 KPEVTPVK-VPEAPKEVVPEKKVPV--PPPKKPEVPPTKV------PEVPKVAVPEKKVP 10651
Query: 671 LSPPPEESPTSPPPEASR------LSPPP-----EDSPTSPPPEDSPASPPPEDSLMSLP 719
+ PP+ P SPPPE L PP E P +PP P P +
Sbjct: 10652 EAIPPK--PESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV 10709
Query: 720 LEESPLLP---LPEEP-QLCPRSEGPHLSP-RPEEPHLS----PR----------PEEPH 760
+ + P LP +PE P ++ P + P + P +PE P P+ P++P
Sbjct: 10710 VAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPE 10769
Query: 761 LSPQAEEPHLSPQP--EEPCLCAVPEEPHLSPQAEGPHLSPQPEEL----HLSPQTEEPH 814
+ P A+ P + +P EE VPE P P + +PEE+ ++P+ E+P
Sbjct: 10770 V-PPAKVPEVPKKPVLEEKPAVPVPERAESPP----PEVYEEPEEIAPEEEIAPEEEKPV 10824
Query: 815 LSPVPEEPCLSPQ--PEE-SHLSPQSEEPCL----SPRPEESHLSPELEKPPLSPRPEKP 867
EEP + P PEE + P+ + P + +P P+E +EKP L PRP P
Sbjct: 10825 PVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPP 10884
Query: 868 PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927
P PAP + + + + L P P +P + E PL G
Sbjct: 10885 P------PAPPKEDV-----KEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVR 10933
Query: 928 QLMP---PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPI--LETPI 982
+L+P P+P + + P P E + K + PE P P+ +E P
Sbjct: 10934 KLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPT 10993
Query: 983 SPPPEANCTDPEPVP------PMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQN 1036
E +P VP P+ P P I P+ P+ +P+ VP
Sbjct: 10994 VTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVV 11053
Query: 1037 SPPSQCSPPALPLSVP-SPLSPIGKVVGVSDEAELHEM 1073
++ P + P P+ + K EAE ++
Sbjct: 11054 GKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKL 11091
Score = 169 bits (429), Expect = 5e-41
Identities = 192/689 (27%), Positives = 282/689 (40%), Gaps = 130/689 (18%)
Query: 402 TSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP 461
T + P++ P + P + +E ++ P E P +PP + + PP E P
Sbjct: 10457 TKVVPRKEPPAKVPEVP---KKIVVEEKVRVP---EEPRVPPTKVPEVLPPKEVVPEKKV 10510
Query: 462 PEASRLSPPPEELPASP---LPEALHLSRPLEESPLSPP--PEESPLSPP-------PES 509
P PP + P +P +PEA P ++ P+ PP PE P P PE
Sbjct: 10511 PV------PPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEK 10564
Query: 510 SPFSPLEESPLSPPEESPPS-----PALETPLSPP--PEASPLSPP------FEESPLSP 556
+ P SPP E P + P + P +PP PE +P+ P E +
Sbjct: 10565 KVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPV 10624
Query: 557 PPEELPTSPP---PEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE 613
PP + P PP PE +++ P ++ P + PP+ P SPPPE +F EE L PP
Sbjct: 10625 PPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPK--PESPPPE---VFEEPEEVALEEPPA 10679
Query: 614 ESPLSPPPEASRLSPPPEDS--PMSPPPEESPMSPPPEVSRLSP--LPVVSRLSPPPEES 669
E P P A PP+ + P P PE+ + + L P +P V + P ++
Sbjct: 10680 EVVEEPEPAA-----PPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKV 10734
Query: 670 PLSPPPE-ESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP--PEDSLMSLPLEESPLL 726
PL P + E+P + PE + P + PE PA P P+ + LEE P +
Sbjct: 10735 PLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPV----LEEKPAV 10790
Query: 727 PLPEEPQLCPRSEGPHLSPRPE----EPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782
P+PE + P P + PE E ++P E+P + EEP + P AV
Sbjct: 10791 PVPERAESPP----PEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPP-------AV 10839
Query: 783 PEEP-HLSPQAEGPHL----SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPE-------E 830
PEEP + P+ + P + +P P+E E+P L P P P +P E +
Sbjct: 10840 PEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQ 10899
Query: 831 SHLSPQSEEPCLSPRPEESHLSPEL----EKPPLSPRPEKPPEEPGQCPAPEELPLFPPP 886
P+ + P PE+ L+P EK PE+ PE + L P
Sbjct: 10900 LKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEE 10959
Query: 887 GEPSLSP----LLGEPALSEPGEPPLSPLPE-ELPLSPS-----GEPSLSPQLMP----- 931
EP + P + +PA+ EP PP P+ E E+P EP+ P++ P
Sbjct: 10960 EEPKVEPKKLEKVKKPAVPEP--PPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLP 11017
Query: 932 -PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPE-SPLAAPILETPISPPPEAN 989
P+P P P + + T PP +PE +P+AAP+ + EA
Sbjct: 11018 APEPKPKPEAEVKTIKPPPV-----------------EPEPTPIAAPVTVPVVGKKAEAK 11060
Query: 990 CTDPEPVPPMILPPSPGSPVGPASPILME 1018
E P P G P SPI E
Sbjct: 11061 APKEEAAKPK--GPIKGVPKKTPSPIEAE 11087
Score = 162 bits (411), Expect = 7e-39
Identities = 246/920 (26%), Positives = 353/920 (38%), Gaps = 178/920 (19%)
Query: 406 PKEPGPLQCEAKPLGK---AGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPP 462
P++P P + + P+ K A P++ E++P+L P +E P E P P P
Sbjct: 9954 PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013
Query: 463 EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPP---ESSPFSPLEESP 519
E P P+++ A P + E P P PE+ P P E+ P E
Sbjct: 10014 EEKVPVPVPKKVEAPP--------AKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPK 10065
Query: 520 LSPPEESPPSPALETPLSPPPEAS--------PLSPPFEESPL-----SPPPEELPTSPP 566
PEE P+P + +PPP+ P++ P EE L P E LP
Sbjct: 10066 KLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEE 10125
Query: 567 --PEASRLSPPPEE---SPMSPPPEESPMSPP----PEASRLFPPFEESPLSPPPEESPL 617
PE + P EE PPEE + P PE P E P P P
Sbjct: 10126 VLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVP- 10184
Query: 618 SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL------------SPLPVVSRLSPP 665
+P PE + E + P EE+P + PEV + LPV ++
Sbjct: 10185 APVPEIKK--KVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPV--EVTEE 10240
Query: 666 PEESPLSPPPEESPTSPP--PEASRLSPP--PE----DSPTSPPPEDSPASPPPEDSLMS 717
PEE P+S EE P PP E ++PP PE P +P P PP
Sbjct: 10241 PEEEPIS--EEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKK 10298
Query: 718 LPLEESPLLPLPEEPQLCPRSEGPHLSPR-PEEPHLSPRPE--EPHLSPQAEEPHLSPQP 774
+P E+ +P+P + + P ++ P + + PE+ L P+ E P E +S
Sbjct: 10299 IPEEK---VPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAF 10355
Query: 775 EEPCLCAVPEEPHLSPQAEGPHLSPQPEELH-LSPQTEEPHLSPVPEEPCLSP-QPEESH 832
+ + V E L P+ EE H + EE V E L + EE H
Sbjct: 10356 RQEVV--VKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEH 10413
Query: 833 LSP---------QSEEPCLSPRPEESHLSPEL-------EKPP--LSPRPEKP---PEEP 871
++EE + +P+ PE+ +KPP + PR E P PE P
Sbjct: 10414 RVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVP 10473
Query: 872 GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPE-ELPLSPSGEPSLSPQLM 930
+ E++ + P EP + P L PP +PE ++P+ P+ +P P +
Sbjct: 10474 KKIVVEEKVRV---PEEPRVPPTKVPEVL-----PPKEVVPEKKVPVPPAKKPEAPPPKV 10525
Query: 931 P-------PD---PLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILET 980
P P+ P+PPP P + PP P E P A PE + I
Sbjct: 10526 PEAPKEVVPEKKVPVPPPKKPEV----PPTKVP----EVPKAAV----PEKKVPEAIPPK 10573
Query: 981 PISPPPEANCTDPEPVPPMILPPSPGS---------PVGPAS--PILMEPLPPQCSPLLQ 1029
P SPPPE E VP +P +P P P P P+PP P +
Sbjct: 10574 PESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVP 10633
Query: 1030 HSLVPQ---NSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPAL 1086
+ VP+ + P + P A+P P P SP +V +E L E E V EPE PA
Sbjct: 10634 PTKVPEVPKVAVPEKKVPEAIP---PKPESPPPEVFEEPEEVALEEPPAEVVEEPE-PAA 10689
Query: 1087 EPSATSPLPSPMGDLSCPA---------PSPAPALDDFSGLGEDTAPL---DGIDAPGSQ 1134
P T P P+ + PA P P + + E PL +AP ++
Sbjct: 10690 PPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPK-EVVPEKKVPLVVPKKPEAPPAK 10748
Query: 1135 ----------------PEPGQTPGSLASELKGSPVL-----LDPEELAPVTPMEVYPECK 1173
P+ + P + E+ PVL + E A P EVY E +
Sbjct: 10749 VPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPE 10808
Query: 1174 QTAGQGSPCEEQEEPRAPVA 1193
+ A + E+E+P PVA
Sbjct: 10809 EIAPEEEIAPEEEKP-VPVA 10827
Score = 160 bits (406), Expect = 3e-38
Identities = 171/650 (26%), Positives = 262/650 (40%), Gaps = 95/650 (14%)
Query: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433
P EP PT P+ L PK + P++ P+ KP E E
Sbjct: 10485 PEEPRVPPTKVPEVL------PPK-----EVVPEKKVPVPPAKKPEAPPPKVPEAPKEVV 10533
Query: 434 LNEEMPLLPP--PEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEE 491
+++P+ PP PE P P P + PP E P +PEA P ++
Sbjct: 10534 PEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKK 10593
Query: 492 SPLSPP--PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF 549
P +PP PE +P+ P P ++ P+ PP++ E P + PE ++ P
Sbjct: 10594 VPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKP------EVPPTKVPEVPKVAVPE 10647
Query: 550 EESPLSPPPEELPTSPPPEASR------LSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603
++ P + PP+ P SPPPE L PP E P P P P +
Sbjct: 10648 KKVPEAIPPK--PESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKK 10705
Query: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR----LSPLPVV 659
+ ++ PE P+ P + P + + P E+P + PEV + + V
Sbjct: 10706 APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765
Query: 660 SRLSPPP---EESPLSPPPEESPTSPPPEASRLSPPPE--DSPTSPPPEDSPASPPPEDS 714
+ PP E P P EE P P PE + SPPPE + P PE+ A P E+
Sbjct: 10766 KKPEVPPAKVPEVPKKPVLEEKPAVPVPERAE-SPPPEVYEEPEEIAPEEEIA--PEEEK 10822
Query: 715 LMSLPLEESPLLP---LPEEP-QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHL 770
+ + EE P +P +PEEP ++ P + P + +PE +P P+EP E+P L
Sbjct: 10823 PVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIK-KPE----APPPKEPEPEKVIEKPKL 10877
Query: 771 SPQPEEPCLCAVPEEP--------HLSPQAEGPHLSPQPEELHLSPQT----EEPHLSPV 818
P+P P A P+E P+ + P PE++ L+P E+ +
Sbjct: 10878 KPRPPPP-PPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLL 10936
Query: 819 PEEPCLSPQPEES-------HLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEP 871
PE P+P+E P+ EEP + P+ E P + +PP P+P + E P
Sbjct: 10937 PER---KPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPP-PPKPVEEVEVP 10992
Query: 872 GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMP 931
++P P P + P + PL P PE P +P + +
Sbjct: 10993 TVTKRERKIP--EPTKVPEIKPAI-----------PL-PAPE-----PKPKPEAEVKTIK 11033
Query: 932 PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETP 981
P P+ P +PI P + E + P + + P+ P+ +TP
Sbjct: 11034 PPPVEPEPTPIAAPVTVPVVGKKAEAKAP--KEEAAKPKGPIKGVPKKTP 11081
Score = 160 bits (405), Expect = 3e-38
Identities = 194/723 (26%), Positives = 290/723 (40%), Gaps = 101/723 (13%)
Query: 491 ESPLSPP--PEESPLSPPPESSPFS--PLEESPLSPPEESPPSPALETPLSPPPEASPLS 546
E P +PP PE S PP+ P P +E P PE P +E + P E P
Sbjct: 10434 EKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEV-PKKIVVEEKVRVPEE--PRV 10490
Query: 547 PPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE--ESPMSPPPEASRLFPPFE 604
PP + + PP E +P P PP + P +PPP+ E+P PE PP +
Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPV------PPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPK 10544
Query: 605 ESPLSP-----------PPEESPLSPPPEASRLSPPPE--DSPMSPPPEESPMSPPPEVS 651
+ + P P ++ P + PP+ SPPPE ++P PE+ + PP+
Sbjct: 10545 KPEVPPTKVPEVPKAAVPEKKVPEAIPPKPE--SPPPEVPEAPKEVVPEKKVPAAPPKKP 10602
Query: 652 RLSPLPVVSRLSPPPEESPLSPPPEESPTSPP---PEASRLSPPPEDSPTSPPPEDSPAS 708
++P+ V E + PP + P PP PE +++ P + P + PP+ P S
Sbjct: 10603 EVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPK--PES 10660
Query: 709 PPPE--DSLMSLPLEESPLLPLPE-EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSP-Q 764
PPPE + + LEE P + E EP P+ P P PE+ + ++P L P +
Sbjct: 10661 PPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVK 10720
Query: 765 AEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQ--PEELHLSPQTEEPHLSPVPEEP 822
E PE+ VP++P +P A+ P + + PE+ P+ E + VPE P
Sbjct: 10721 VPEVPKEVVPEKKVPLVVPKKPE-APPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVP 10779
Query: 823 CLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCP-APEELP 881
P EE P E SP PE E ++P E PEE P A EE P
Sbjct: 10780 -KKPVLEEKPAVPVPER-AESPPPEVYE-----EPEEIAPEEEIAPEEEKPVPVAEEEEP 10832
Query: 882 LFPPPGEP----SLSPLLGEPALSEP-GEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
PPP P + P P + +P PP P PE++ +P L P+ PP P P
Sbjct: 10833 EVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKV----IEKPKLKPRPPPPPPAP 10888
Query: 937 P--------------PLSPIITAAAPPALSPLGELEYPFGAK------GDSDPESPLAAP 976
P P + P L L+ P G K + PE P
Sbjct: 10889 PKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPE-PKEEV 10947
Query: 977 ILETPISPPPEAN--CTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVP 1034
+L++ + PE +P+ + + P P P P P+ +P + + +P
Sbjct: 10948 VLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPP--PPKPVEEVEVP---TVTKRERKIP 11002
Query: 1035 QNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL 1094
+ + + PA+PL P P EAE+ ++ V EPE + T P+
Sbjct: 11003 EPTKVPEIK-PAIPLPAPEPKP--------KPEAEVKTIKPPPV-EPEPTPIAAPVTVPV 11052
Query: 1095 PSPMGDLSCPAPSPAPALDDFSGLGEDT-APLDGID---APGSQPEPGQTPGSLASELKG 1150
+ P A G+ + T +P++ PGS E +LK
Sbjct: 11053 VGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKA 11112
Query: 1151 SPV 1153
P+
Sbjct: 11113 VPL 11115
Score = 136 bits (342), Expect = 7e-31
Identities = 239/1002 (23%), Positives = 359/1002 (35%), Gaps = 194/1002 (19%)
Query: 374 PPEPGDTPTDEPDALYVACQGQ--PKGGHVTSMQPKEPGPLQCEA--KPLGKAGVQLEPQ 429
PPE + P +E YV + + P+ + ++PK P P K + + V + +
Sbjct: 10148 PPEEEEVPPEEE---YVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKK 10204
Query: 430 LEAP----------LNEEMPLLPPPEES---PLSPPPEESPTSPP--PEASRLSPPPEEL 474
EAP + E+ +LP EE ++ PEE P S PE EE+
Sbjct: 10205 EEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEV 10264
Query: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLS-PPEESPPSPALE 533
+PE + + P +P+ E +PP + S P E+ P+ +E+PP+ E
Sbjct: 10265 APPRVPEVIKKAVPEAPTPVPKKVE----APPAKVSKKIPEEKVPVPVQKKEAPPAKVPE 10320
Query: 534 TPLSPPPEASPLSPPFEESPLSPP----PEELPTSPPPEA---SRLSPPPEESPMSPPPE 586
P PE L P E P + E++ + E RL E+ + PE
Sbjct: 10321 VP-KKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPE 10379
Query: 587 ESPMSPPPE-----------------------------ASRLFPPFEESPLSPPPEESPL 617
E E R+ FE + E P
Sbjct: 10380 EEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEV--FEKPK 10437
Query: 618 SPP--PEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
+PP PE S PP+ P P + P + PEV + + R+ P P P
Sbjct: 10438 APPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPE 10497
Query: 676 EESPTSPPPEASRLSPPPEDSPTSPPP-EDSPASPPPEDSLMSLPLE--ESPLLPLPEEP 732
P PE PP + PP ++P PE + P + E P +PE P
Sbjct: 10498 VLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVP 10557
Query: 733 QLC-PRSEGPH-LSPRPEEPHLSPRPEEP----HLSPQAEEPHLSPQPEEPCLCAVPEEP 786
+ P + P + P+PE SP PE P + P+ + P P+ E VPE P
Sbjct: 10558 KAAVPEKKVPEAIPPKPE----SPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAP 10613
Query: 787 -HLSPQAEGPHLSPQ----------------------PEELHLSPQTEEPHLSPVPEEPC 823
+ P+ + P P+ PE + P++ P + PEE
Sbjct: 10614 KEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVA 10673
Query: 824 LSPQP------EESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAP 877
L P E PQ P P PE+ + +KP L P K PE P +
Sbjct: 10674 LEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELP--PVKVPEVPKEVVPE 10731
Query: 878 EELPLF-------PPPGEPSL-SPLLGEPALSEPGEP----------PLSPLPEELPLSP 919
+++PL PP P + ++ E ++ P +P P P+ EE P P
Sbjct: 10732 KKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVP 10791
Query: 920 SGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAA---- 975
E + SP PP+ P A ++P E E P + +PE P A
Sbjct: 10792 VPERAESP---PPEVYEEPEE----IAPEEEIAP--EEEKPVPVAEEEEPEVPPPAVPEE 10842
Query: 976 ----------PILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQ-- 1023
P+++ P +PPP+ EP P ++ P P P P PP+
Sbjct: 10843 PKKIIPEKKVPVIKKPEAPPPK------EPEPEKVIEKPKLKPRPPPPP----PAPPKED 10892
Query: 1024 -CSPLLQHSLVPQNSPPSQCSPP----ALPLSVPSPLSPIGKVVGVSDEAELHEMETEKV 1078
+ Q +P+ P + P PL VP + K++ E+ + V
Sbjct: 10893 VKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSV 10952
Query: 1079 ----SEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS---------GLGEDT-AP 1124
E E P +EP + P + P P P +++ + E T P
Sbjct: 10953 LRKRPEEEEPKVEPKKLEKVKKP----AVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVP 11008
Query: 1125 LDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEEL-APVTPMEVYPECKQTAGQGSPCE 1183
P PEP P + +K PV +P + APVT P + A +P E
Sbjct: 11009 EIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVT----VPVVGKKAEAKAPKE 11064
Query: 1184 EQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEP 1225
E +P+ P+ P S I E L G P P
Sbjct: 11065 EAAKPKGPIKGVPKK-TPSPIEAERRKLRPGSGGEKPPDEAP 11105
Score = 122 bits (306), Expect = 1e-26
Identities = 222/896 (24%), Positives = 329/896 (36%), Gaps = 184/896 (20%)
Query: 438 MPLLPPPEE----SPLSPP--------PEESPTSPPPEASRLSPPPEELPASP---LPEA 482
+P+ P PEE P +PP PEE P P+ +L PPP ++P P E
Sbjct: 9793 IPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPK--KLKPPPPKVPEEPKKVFEEK 9850
Query: 483 LHLS-RPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPE 541
+ +S E+ ++ P + P+ P + E+ P+ E +PP E P E
Sbjct: 9851 IRISITKREKEQVTEPAAKVPMKPKRVVAE----EKVPVPRKEVAPPVRVPEVP----KE 9902
Query: 542 ASPLSPPFEESPLSPPPEELPTSPPP---EASRLSPPPE----------ESPMSPPPEES 588
P FEE ++ E L E E E P P PEE
Sbjct: 9903 LEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEK 9962
Query: 589 PMSPPPEASRLFP---------PFEESP-LSPPPEESPLSPPPEASRLSPPPEDSPMSPP 638
P P+ P P E+ P L P E+ P + PE + P E P+ P
Sbjct: 9963 KPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVP 10022
Query: 639 PE-ESPMSPPPEV------SRLSPLPVVSRLSPPPEESPLSPP---PEESPTSPPPEASR 688
+ E+P + PEV + P+P ++ PP + P P PEE +P P+ +
Sbjct: 10023 KKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPK--K 10080
Query: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP----LPEEPQLCPRSEGPHLS 744
+ PP P P P + P E+ + L E ++P LPEE ++ P E +
Sbjct: 10081 VEAPPPKVPKKREPVPVPVALPQEEEV----LFEEEIVPEEEVLPEEEEVLPEEE--EVL 10134
Query: 745 PRPEEPHLSPRPEEPHLSPQAEE--PHLSPQPEEPCLCAVPEE---PHLSPQAEGPHLSP 799
P EE PEE + P+ EE P PEE VPEE P + P+ P P
Sbjct: 10135 PEEEE----VLPEEEEIPPEEEEVPPEEEYVPEEEEF--VPEEEVLPEVKPKVPVPAPVP 10188
Query: 800 Q-----PEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854
+ E+ + P+ EE + VPE P + EE + EE L P E ++ E
Sbjct: 10189 EIKKKVTEKKVVIPKKEEAPPAKVPEVP---KKVEEKRIILPKEEEVL---PVE--VTEE 10240
Query: 855 LEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL----SPLLGEPALSEPGEPPL-- 908
E+ P+S E+ PEEP P+ EE+ PP P + P P + PP
Sbjct: 10241 PEEEPIS--EEEIPEEP---PSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKV 10295
Query: 909 -SPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIIT---AAAPPALS-PLGELEYPFGA 963
+PEE P + P +P P P ++ A PPA + E +
Sbjct: 10296 SKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAF 10355
Query: 964 KGDSDPESPLAAPILETPISPPPE------------------------------------ 987
+ + + L ++E + PE
Sbjct: 10356 RQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRV 10415
Query: 988 ------ANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQ 1041
+ E V P +P P GP I + +PP+ P +VP+ PP++
Sbjct: 10416 EKVHRVIEVFEAEEVEVFEKPKAP--PKGP--EISEKIIPPKKPPT---KVVPRKEPPAK 10468
Query: 1042 CSPPALPLSV---------PSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATS 1092
P +P + P P KV V E+ + +KV P PA +P A
Sbjct: 10469 V--PEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEV--VPEKKVPVP--PAKKPEAPP 10522
Query: 1093 P-LPSPMGDL--SCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELK 1149
P +P ++ P P P + P + P S E+
Sbjct: 10523 PKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVP 10582
Query: 1150 GSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAP-----TPPTLI 1200
+P + PE+ P P + PE +P E E + PV P PPT +
Sbjct: 10583 EAPKEVVPEKKVPAAPPK-KPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKV 10637
Score = 119 bits (298), Expect = 8e-26
Identities = 177/727 (24%), Positives = 255/727 (35%), Gaps = 157/727 (21%)
Query: 415 EAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPP---P 471
EA P KA V EP+ P + + L P EE P + E E + P P
Sbjct: 9657 EAPP--KARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREP 9714
Query: 472 EELPASPLPEALHLSRPLEESPLSPPPEE-------------SPLSPPPESSPFSPLEES 518
+ + + E + LEE +S EE P E + EE
Sbjct: 9715 QPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEER 9774
Query: 519 P-----------LSPPEESPPSPALETPLSPPPEASPL-----SPPFEESP------LSP 556
P + P P E P+ P+A P + P E+ P L P
Sbjct: 9775 EYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKP 9834
Query: 557 PPEELPTSPPP-------------EASRLSPPPEESPMSP---------PPEESPMSPP- 593
PP ++P P E +++ P + PM P P ++PP
Sbjct: 9835 PPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPV 9894
Query: 594 --PEASRLFPP-------------------------FEESPLSPPPEESPLSP--PPEAS 624
PE + P EE E P+ P PE
Sbjct: 9895 RVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVP 9954
Query: 625 RLSPPPEDSPMS-PPPEESPMSPPPEVSRLS----PLPVVSRLSPPP---EESPLSPPPE 676
R P E P+ P +E+P + PEV + P+ + + PPP E P P PE
Sbjct: 9955 RKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPE 10014
Query: 677 ESPTSPPPEASRLSPPP---EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP- 732
E P P+ ++ PP + P P PE P P+ E+P +PE P
Sbjct: 10015 EKVPVPVPK--KVEAPPAKVPEVPKKPVPEKKVPVPAPKK-------VEAPPAKVPEVPK 10065
Query: 733 QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA 792
+L P + P P+ E +P P+ P P PQ EE V E + P+
Sbjct: 10066 KLIPEEKKPTPVPKKVE---APPPKVPKKREPVPVPVALPQEEE-----VLFEEEIVPEE 10117
Query: 793 EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLS 852
E PEE + P+ EE +PEE PEE + P+ EE PEE ++
Sbjct: 10118 E-----VLPEEEEVLPEEEE----VLPEEE--EVLPEEEEIPPEEEE----VPPEEEYVP 10162
Query: 853 PELE-KPPLSPRPEKPPEEPGQCPAPE-------------ELPLFPPPGEPSLSPLLGEP 898
E E P PE P+ P P PE + PP P + + E
Sbjct: 10163 EEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEK 10222
Query: 899 ALSEPGEPPLSPL-----PEELPLSPSGEPSLSPQLMPPDPLPPPLSP-IITAAAPPALS 952
+ P E + P+ PEE P+S P P + + + PP P +I A P A +
Sbjct: 10223 RIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPT 10282
Query: 953 PL-GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGP 1011
P+ ++E P PE + P+ + P P +++P P
Sbjct: 10283 PVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAK 10342
Query: 1012 ASPILME 1018
+L E
Sbjct: 10343 GRTVLEE 10349
Score = 116 bits (291), Expect = 5e-25
Identities = 226/927 (24%), Positives = 325/927 (35%), Gaps = 165/927 (17%)
Query: 428 PQL-EAPLNEEMPLLPPPEE-SPLSPPPEESPTSPPPEASRLSPPPEELPASP--LPEAL 483
P+L E P EE+ +P P++ P +P E P P PE + P P++ PA+P +PE
Sbjct: 9289 PELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVP 9348
Query: 484 HLSRPLEESPLS-PPPEESPLSPPPESSPFSPLEE--SPLSPPEESPPSPALETPLSP-P 539
P E+ P+ +E+P + PE EE + ++ EESPP E P P
Sbjct: 9349 KKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVP 9408
Query: 540 PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRL 599
E P+ EE P P LP P PE P P PP E E R
Sbjct: 9409 EERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKR- 9467
Query: 600 FPPFEESPLSPP------------PEESPLSPPPEASRLS----PPPEDSPMSPPPEESP 643
F E+ + P EE S E +S E+ + E
Sbjct: 9468 FVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEV 9527
Query: 644 MSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSP--- 700
M P E L ++S+ ++ P A PPP P +P
Sbjct: 9528 MEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKI 9587
Query: 701 -PPEDSPASPPPEDSLMSLPLEESPLLPLPEE--PQLCPRSEGPHLSPRPEEPHLSPRPE 757
P + PA P ++ + + E P P+PE+ P + E P L + E H+ E
Sbjct: 9588 VPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEP-LPAKVTERHMQITQE 9646
Query: 758 EPHL--SPQAEEPHLSPQPEEPCLCAVPEEPHL--------SPQA--------------- 792
E L + E P + PEEP AVPEE L P A
Sbjct: 9647 EKVLVAVTKKEAPPKARVPEEP-KRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKV 9705
Query: 793 --EGPHLSPQP-EELHLSPQTEEPHLSPVPEEPCLSPQPEESHLS--------------- 834
E P PQP +E+ + + E + EE +S Q EE +
Sbjct: 9706 SIEAPKREPQPIKEVTIMEEKERAY---TLEEEAVSVQREEEYEEYEEYDYKEFEEYEPT 9762
Query: 835 ------PQSEEPCLSPRPEESHLSPELEKP-PLSPRPEKP-----------------PEE 870
+ EE E E EKP P+ P PE+P PEE
Sbjct: 9763 EEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEE 9822
Query: 871 PGQCPAPEELPLFPP--PGEPSL--------------SPLLGEPALSEPGEPPLSPLPEE 914
P P++L PP P EP + EPA P +P E+
Sbjct: 9823 KVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEK 9882
Query: 915 LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL-----------EYPFGA 963
+P+ ++P + P+ +P L P A ++ + E E F
Sbjct: 9883 VPVP---RKEVAPPVRVPE-VPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFIT 9938
Query: 964 KGDSDPESPLAAPILETPISPPPEANCTDPEP----VPPMILPPSPGSPVGPASPILM-- 1017
+ + P P+ P E P P PE P P PP +P P P P+L+
Sbjct: 9939 EEEVVPVIPVKVP--EVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKV-PVLIPK 9995
Query: 1018 -EPLPPQCSPLLQHSLVPQNSPPSQC-----SPPALPLSVPSPLSPIGKVVGVSDE---- 1067
E PP P + VP+ P +PPA VP P KV + +
Sbjct: 9996 KEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEA 10055
Query: 1068 --AELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPL 1125
A++ E+ + + E + P P P + P P P + L E+
Sbjct: 10056 PPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEE---- 10111
Query: 1126 DGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQ 1185
+ + PE + L +L EE P EV PE + + E+
Sbjct: 10112 EIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEE 10171
Query: 1186 E-----EPRAPVAPTPPTLIKSDIVNE 1207
E +P+ PV P P IK + +
Sbjct: 10172 EVLPEVKPKVPV-PAPVPEIKKKVTEK 10197
Score = 92.0 bits (227), Expect = 1e-17
Identities = 127/505 (25%), Positives = 189/505 (37%), Gaps = 45/505 (8%)
Query: 445 EESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL---SPPPEES 501
E+ ++ PE S P + SR +P EE+ +P + E + S EE
Sbjct: 9199 EKVQVTKVPEVSKKIVPQKPSR-TPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEV 9257
Query: 502 PLSPPPESSPFSPLEESPLSPPEESPPSPAL-ETPLSPPPE-ASPLSPPFEESPLSPPPE 559
++ P E+ ++ + P P + E P P PE +P+ P + P +P
Sbjct: 9258 SVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVP 9317
Query: 560 ELPTSPPPEASRLSPPPEESPMSPPP-EESPMSPPPEASRLFPPFEESPLSPPPEESPLS 618
E+P P PE + P P++ P +PP E P P PE P ++ +E+P +
Sbjct: 9318 EVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKK-------KEAPPA 9370
Query: 619 PPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEES 678
PE + E + EE SPPP V P + + P E P+ EE
Sbjct: 9371 KVPEVQKGVVTEEKITIVTQREE---SPPPAV------PEIPKKKVPEERKPVPRKEEEV 9421
Query: 679 PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPR- 737
P P A P PE+ P P A PP + +EE + + P+
Sbjct: 9422 PPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQR 9481
Query: 738 -SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPH 796
H EE S E +S EE + E V EEP E H
Sbjct: 9482 VEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLH 9541
Query: 797 LSPQPEELHLSPQTE--------EPHLSPVPEEPCLSPQPE-ESHLSPQSEEPCLSPRPE 847
+ + E + TE +P + EEP + PE + P+ + P P+ E
Sbjct: 9542 IISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKE 9601
Query: 848 ESHLSPELEKPPLSPRPEK--PP-----EEPGQCPAPEELPLFPPPGEPSLSPLLGE-PA 899
+ P++ + P P PEK PP EEP E + ++ E P
Sbjct: 9602 KVP-PPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPP 9660
Query: 900 LSEPGEPPLSPLPEE--LPLSPSGE 922
+ E P +PEE L L P E
Sbjct: 9661 KARVPEEPKRAVPEEKVLKLKPKRE 9685
Score = 88.6 bits (218), Expect = 2e-16
Identities = 206/954 (21%), Positives = 324/954 (33%), Gaps = 155/954 (16%)
Query: 367 PVCSRFSPPEPG-----DTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGK 421
P+ + PP P P E + +P PK+P P + P+ K
Sbjct: 9304 PIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAK 9363
Query: 422 ---AGVQLEPQLEAPL--NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPA 476
A P+++ + E++ ++ EESP PE P E + EE+P
Sbjct: 9364 KKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPP 9423
Query: 477 SPLPEALHLSRPLEESPLSPPPEESPLSPPP----------ESSPFSPLEESPLSPPE-- 524
P AL +P+ E ++ P + +PPP E F E+ + P+
Sbjct: 9424 PPKVPALP-KKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRV 9482
Query: 525 ---ESPPSPALETPLSPPPEASPLSPPFEES------------PLSPPPEE--------- 560
S E S E +S EE + PEE
Sbjct: 9483 EVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHI 9542
Query: 561 LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPP 620
+ E + ++ E+ + P + + PP A E+P PE+ +P
Sbjct: 9543 ISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAK-----VPEAPKKIVPEKKVPAPV 9597
Query: 621 PEASRLSPP--PEDSPMSPPPEESPMSPPPEVSRLSPLP--VVSRLSPPPEESPL----- 671
P+ ++ PP PE+ P P PE+ PP + PLP V R +E +
Sbjct: 9598 PKKEKVPPPKVPEE-PKKPVPEKK--VPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVT 9654
Query: 672 ---SPP----PEESPTSPPPE-ASRLSPPPEDSPTSPPPE-------------DSPASPP 710
+PP PEE + P E +L P E+ P + E ++P P
Sbjct: 9655 KKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREP 9714
Query: 711 P--------EDSLMSLPLEESPLLPLPEE-------------PQLCPRSEGPHLSPRPEE 749
E+ + LEE + EE + P E E
Sbjct: 9715 QPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEER 9774
Query: 750 PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQ 809
+ E +++ + + P PEEP VP +P P P+ + P+
Sbjct: 9775 EYERYEEHEEYITEPEKPIPVKPVPEEP----VPTKPKAPPAKVLKKAVPEEKVPVPIPK 9830
Query: 810 TEEPHLSPVPEEP----------CLSPQPEESHLSPQSEEPCLSPR--PEESHLSPELEK 857
+P VPEEP ++ + +E P ++ P R EE P E
Sbjct: 9831 KLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEV 9890
Query: 858 PPLSPRPEKPPE-EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELP 916
P PE P E EP + EE+ L+ E E E +P
Sbjct: 9891 APPVRVPEVPKELEPEEVAFEEEVVTHVE------EYLVEEEEEYIHEEEEFITEEEVVP 9944
Query: 917 LSPSGEPSLSPQLMPPD--PLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLA 974
+ P P + + +P + P+P P A P + E + P E P
Sbjct: 9945 VIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLI---PKKEKPPP 10001
Query: 975 APILETPISPPPEANCTDPEP----VPPMILPPSPGSPVGPASPILMEP----LPPQCSP 1026
A + E P P PE P P PP +P P PV + P PP P
Sbjct: 10002 AKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVP 10061
Query: 1027 LLQHSLVPQNSPPSQC--SPPALPLSVPSPLSPIGKVVGVSDEAEL---HEMETEKVSEP 1081
+ L+P+ P+ A P VP P+ V + E E+ E+ E+ P
Sbjct: 10062 EVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLP 10121
Query: 1082 ECPALEPSATSPLPS-----PMGDLSCPAPSPAPALDDFSGLGEDTAPLDGI--DAPGSQ 1134
E + P LP P + P P +++ E+ P + + +
Sbjct: 10122 EEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKV 10181
Query: 1135 PEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEP 1188
P P P + ++ V++ +E AP + P+ + P EE+ P
Sbjct: 10182 PVPAPVP-EIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLP 10234
Score = 71.2 bits (173), Expect = 3e-11
Identities = 139/597 (23%), Positives = 203/597 (34%), Gaps = 82/597 (13%)
Query: 2083 QINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGF 2142
++ K+ V + R + P R+PP PP P + P PA
Sbjct: 10471 EVPKKIVVEEKVRVPEEP----RVPPTKVPEVLPPKEVVPEKKV--PVPPAK-------- 10516
Query: 2143 LKPPAGSVPGPDSPGELFLKL-----PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYP 2197
KP A P++P E+ + PP+ P P++ P A P E + P A P P
Sbjct: 10517 -KPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVP-EKKVPEAIPPKP 10574
Query: 2198 PYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTP---PGTPRHQ-PSTPDPFLKPRCPSLD 2253
P P P P + + A P + TP P P+ P P P+ P +
Sbjct: 10575 ESPPPE-VPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVP 10633
Query: 2254 NLAVPESPGVGGGKASEPLL------SPPP--FGESRK-ALEVKKEELGASSPSYGPPNL 2304
VPE P V + P SPPP F E + ALE E+ PP +
Sbjct: 10634 PTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQV 10693
Query: 2305 GFVDS-PSSGTHLGGLELKTPDV--FKAPLTPRASQVEPQSPGLGLRPQEPPPAQA---- 2357
P + K P++ K P P+ E + P + + E PPA+
Sbjct: 10694 TVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVP 10753
Query: 2358 --LAPSP----PSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSL-------P 2404
+ P P P++ P + +P L +P P PE + PP P
Sbjct: 10754 KEVVPEKKVAVPKKPEV-PPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAP 10812
Query: 2405 SDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSP---DPYSRPPSRPQ--- 2458
+ + P + + P P P E P + P + P P + PP P+
Sbjct: 10813 EEEIAPEEEKPVPVAEEEEPEVPPPAVPEE--PKKIIPEKKVPVIKKPEAPPPKEPEPEK 10870
Query: 2459 --SRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGEL-HAKVPSGQP 2515
+ P PP P PP+ K ++ P EL KVP G+
Sbjct: 10871 VIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEK 10930
Query: 2516 ------PNFVRSPGTGAFVGTPSPMRFTFPQAVGEPS-----LKPPVPQPGLPPPHGINS 2564
P P + + R + EP KP VP+P PPP +
Sbjct: 10931 KVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEP--PPPKPVEE 10988
Query: 2565 HFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621
P T + + T P+ PL + ++PP V P P P
Sbjct: 10989 VEVPTVTKRERKIPEPT-KVPEIKPA-IPLPAPEPKPKPEAEVKTIKPPPVEPEPTP 11043
Score = 67.8 bits (164), Expect = 3e-10
Identities = 123/539 (22%), Positives = 184/539 (34%), Gaps = 111/539 (20%)
Query: 2071 HRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTI------ 2124
HR+ +V + E ++ ++ K + + + PP PPA P +
Sbjct: 10419 HRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVV 10478
Query: 2125 --FIGSPTTPAGLSTSADGFLKP----PAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFG 2178
+ P P T L P P VP P + K P P +VP + P
Sbjct: 10479 EEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPA------KKPEAPPPKVP-EAPKE 10531
Query: 2179 LAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQ- 2237
+ P E + P PP P P PT P P + P + + PP P
Sbjct: 10532 VVP----EKKVPVPPPKKPEVP-PTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPK 10586
Query: 2238 ---PSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPP-PFGESRKALEVKKEELG 2293
P P P+ P + + VPE+P + P+ P P K EV K +
Sbjct: 10587 EVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVP 10646
Query: 2294 ASS-PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLT-----PRASQVEPQSPG--- 2344
P PP +SP P+VF+ P P A VE P
Sbjct: 10647 EKKVPEAIPPK---PESPP------------PEVFEEPEEVALEEPPAEVVEEPEPAAPP 10691
Query: 2345 -LGLRPQEPPP---AQALAPSPPSHPDIFRPGSYTD--PYAQPPLT--PRPQPPP----- 2391
+ + P++P P A A+ P P + P + P + PL +P+ PP
Sbjct: 10692 QVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPE 10751
Query: 2392 ------PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ 2445
PE A+P + P P ++VP P+ + P P P AE SP ++
Sbjct: 10752 VPKEVVPEKKVAVPKK--PEVPPAKVPEVPKKPVLEEKPAVPVPERAE----SPPPEVYE 10805
Query: 2446 SPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGE 2505
P+ + + P+ + P+ P P A+P P
Sbjct: 10806 EPEEIAPEEEIAPEEEKPVPVAEEEEPEVP-------------------PPAVPEEPKKI 10846
Query: 2506 L-HAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKP-PVPQPGLPPPHGI 2562
+ KVP + P P P + + +P LKP P P P PP +
Sbjct: 10847 IPEKKVPVIKKPE------------APPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV 10893
Score = 63.2 bits (152), Expect = 7e-09
Identities = 134/574 (23%), Positives = 199/574 (34%), Gaps = 77/574 (13%)
Query: 425 QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELP---ASPLPE 481
+LEP+ EA E+ L + L PP P P + PPEE+P A P+P
Sbjct: 8908 RLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIP- 8966
Query: 482 ALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP--LSPPEESPPSPALETPLSP- 538
L L P E+ PPP+ ++ + P ++P EE P T L P
Sbjct: 8967 -LLLPTPEEK---KPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPA 9022
Query: 539 -PPEASPLSPPFEESPLSPPPEELPTSPPPEA----------------SRLSPPPEESPM 581
PE +S EE + + EA P +E +
Sbjct: 9023 KAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEV 9082
Query: 582 SP--PPEESPMSPPPEASRLFPPFEESPLSPPPE-----ESPLSPPPEASRLS---PPPE 631
P P E P P+ +EE + E E E E
Sbjct: 9083 EPYTEPFEQPYYEEPDED-----YEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGE 9137
Query: 632 DSPMSPPPEESPMSPPPEV-----SRLSPLPVVSRLSPPPE---ESPLSPPPEESPTSPP 683
+ E + EV R P V + +PPP + P+ E++
Sbjct: 9138 EEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRME 9197
Query: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743
E +++ PE S P + S E + +P + + + EE +
Sbjct: 9198 EEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEV 9257
Query: 744 SPR-PEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPE 802
S PE E+ H+ A + P P+ P +PE+P +P+ P P+
Sbjct: 9258 SVTVPEVQKEIVTEEKIHV---AISKRVEPPPKVP---ELPEKP--APEEVAPVPIPKKV 9309
Query: 803 ELHLSPQTEEPHLSPVPEEPCLSPQP-EESHLSPQSEEPCLSPRPEESHLSPELEKPPLS 861
E +P+ E PVPEE P P +E P+ E P PEE P +K
Sbjct: 9310 E-PPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKK--E 9366
Query: 862 PRPEKPPEEPGQCPAPEELPLF------PPPGEPSLSPLLGEPALSEPGEPPLSPLPEEL 915
P K PE E++ + PPP P + P P E P EE
Sbjct: 9367 APPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEI------PKKKVPEERKPVPRKEEE 9420
Query: 916 PLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP 949
P P+L + +P + + P+ P+ A PP
Sbjct: 9421 VPPPPKVPALPKKPVPEEKVAVPV-PVAKKAPPP 9453
Score = 61.2 bits (147), Expect = 3e-08
Identities = 123/525 (23%), Positives = 178/525 (33%), Gaps = 90/525 (17%)
Query: 2106 IPPQPGALGSPPPAA--APTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELF--L 2161
IPP+P SPPP AP + PA KP V P++P E+
Sbjct: 10570 IPPKPE---SPPPEVPEAPKEVVPEKKVPAAPPK------KPEVTPVKVPEAPKEVVPEK 10620
Query: 2162 KLP------PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPP--YPSPTGAPAQPPMLG 2213
K+P P+VP + P P + P P + PP + P + P
Sbjct: 10621 KVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAE 10680
Query: 2214 ASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLL 2273
P P + T PP P P P + + P L + VPE P + PL+
Sbjct: 10681 VVEEPEPAAPPQV-TVPPKKP--VPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLV 10737
Query: 2274 SPP-PFGESRKALEVKKEELGASS------PSYGP------PNLGFVDSPSSGTHLGGLE 2320
P P K EV KE + P P P ++ + E
Sbjct: 10738 VPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAE 10797
Query: 2321 LKTPDVFKAPL---------------TPRASQVEPQSPGLGLRPQEP---------PPAQ 2356
P+V++ P P A + EP+ P + P+EP P +
Sbjct: 10798 SPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAV-PEEPKKIIPEKKVPVIK 10856
Query: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQ 2416
PP P+ P + P P P P PP+ L + P +VP PQ
Sbjct: 10857 KPEAPPPKEPE---PEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQ 10913
Query: 2417 -SQSSSQSPL----------------TPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS 2459
+ +PL P P E S + R + +P P +
Sbjct: 10914 VPEKVELTPLKVPGGEKKVRKLLPERKPEP-KEEVVLKSVLRKRPEEEEPKVEPKKLEKV 10972
Query: 2460 RDPFAPLHKPPRP----QPPEVAFKAGSLAHTSLGAGGFPA-ALPA-GPAGELHAKVPSG 2513
+ P P PP+P + P V + + + PA LPA P + A+V +
Sbjct: 10973 KKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTI 11032
Query: 2514 QPPNFVRSP-GTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLP 2557
+PP P A V P + +A E + KP P G+P
Sbjct: 11033 KPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVP 11077
Score = 56.2 bits (134), Expect = 9e-07
Identities = 117/551 (21%), Positives = 188/551 (34%), Gaps = 88/551 (15%)
Query: 617 LSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP- 675
L PP P P + PPEE P P + L P P PPP+ ++
Sbjct: 8932 LKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTP--EEKKPPPKRIEVTKKAV 8989
Query: 676 EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLC 735
++ + ++P E PPP + PE +S EE ++ + + ++
Sbjct: 8990 KKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQ 9049
Query: 736 PRSEGPHLSPRPEEPHLSPRP-----EEPHLSPQAE---EPHLSPQPEEP------CLCA 781
E + + + H R EEP+ + E EP P EEP
Sbjct: 9050 KEKEAVY--EKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVE 9107
Query: 782 VPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPC 841
+E H + + E + EE E + Q E S + + P
Sbjct: 9108 AKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPA 9167
Query: 842 LSPRPEESHLSPELEKPPLSPRPEKP----------------------PEEPGQCPAPEE 879
P +++ P++ K P+ + EK P++P + P EE
Sbjct: 9168 KVPE-KKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEE 9226
Query: 880 LPLFPPPGEPSLSPLLGEPAL---SEPGEPPLSPLPE---ELPLSPSGEPSLSPQLMPPD 933
+ P + ++ E + S E +PE E+ ++S ++ PP
Sbjct: 9227 VIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPP 9286
Query: 934 PLPP-PLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTD 992
+P P P AP ++P+ P K + P A + E P P PE
Sbjct: 9287 KVPELPEKP-----APEEVAPV-----PIPKKVE-----PPAPKVPEVPKKPVPEEKKPV 9331
Query: 993 P----EPVPPMILPPSPGSPVG----PASPILMEPLPPQCSPLLQHSLVPQN-----SPP 1039
P EP P +P P PV P + PP P +Q +V + +
Sbjct: 9332 PVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQR 9391
Query: 1040 SQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMG 1099
+ PPA+P +P P + + E E P+ PAL P+P
Sbjct: 9392 EESPPPAVP-EIPKKKVP-------EERKPVPRKEEEVPPPPKVPAL---PKKPVPEEKV 9440
Query: 1100 DLSCPAPSPAP 1110
+ P AP
Sbjct: 9441 AVPVPVAKKAP 9451
Score = 50.8 bits (120), Expect = 4e-05
Identities = 101/444 (22%), Positives = 159/444 (35%), Gaps = 95/444 (21%)
Query: 4619 PPTPPSSLPPTPPPSVQQKMVNGVTPSE------ELGEHPKDAASARDSERALRDTSEVK 4672
P PP+ +P P +V +K V P + E+ E PK+ + A EV
Sbjct: 10546 PEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVT 10605
Query: 4673 SLDLLAA---------LPTPPHNQTE-------DVRMESDEDSDSPDSIVPA-------- 4708
+ + A +P PP + E +V + + P++I P
Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV 10665
Query: 4709 -SSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPG 4767
PE + EE P + E+ + A P + + P+ +P K A+ + P
Sbjct: 10666 FEEPEEVALEEPP------AEVVEEPEPAAPPQVTVPPKKPVP----EKKAPAVVAKKPE 10715
Query: 4768 KLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESP---- 4823
PV E K EV V K V E+ +P +V P+ P
Sbjct: 10716 LPPVKVPEVPK--EVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEK-KVAVPKKPEVPP 10772
Query: 4824 ARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQ----LDILSLL 4879
A+ PKK E +SP P+ ++ + + P + + + +
Sbjct: 10773 AKVPEVPKKPVLEEKPAVPVPERAESPP--PEVYEEPEEIAPEEEIAPEEEKPVPVAEEE 10830
Query: 4880 KQESPAPEPPTQHSYTYNVSNLDV-RQLSAPPPEEPSP---------PPSPLAPSPASPP 4929
+ E P P P + + V ++ APPP+EP P P P P PA PP
Sbjct: 10831 EPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPA-PP 10889
Query: 4930 TEPLVE-------LPTEPLAE-PPVP-----SPLPLASSPESAR-------PKP------ 4963
E + E +P + + E P VP +PL + + R P+P
Sbjct: 10890 KEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVL 10949
Query: 4964 ----RARPPEEGEDSRPPRLKKWK 4983
R RP EE P +L+K K
Sbjct: 10950 KSVLRKRPEEEEPKVEPKKLEKVK 10973
Score = 44.7 bits (104), Expect = 0.003
Identities = 73/354 (20%), Positives = 124/354 (35%), Gaps = 46/354 (12%)
Query: 4620 PTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAA 4679
P PP+ P PPP V + V P +++ P ++ + V + A
Sbjct: 10511 PVPPAKKPEAPPPKVPEAPKE-VVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEA 10569
Query: 4680 LPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSP 4739
+P P + +V ++P +VP E + P+ P + + + + + P
Sbjct: 10570 IPPKPESPPPEV-------PEAPKEVVP----EKKVPAAPPKKPEVTPVKVPEAPKEVVP 10618
Query: 4740 VIPL-IPRASIPVFPDTKPYGALGLEVPGK-LPVTTWEKGKGSEVSVMLTVSAAAAKNLN 4797
+ +P P P TK + VP K +P K + V A +
Sbjct: 10619 EKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPP 10678
Query: 4798 GVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWL 4857
+V E P +P + PKK P K + K P+ P +
Sbjct: 10679 AEVVEEPE--------------PAAPPQVTVPPKKPV---PEKKAPAVVAKKPELPPVKV 10721
Query: 4858 KQFDA-VLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSP 4916
+ V+P + ++ ++ K E+P + P V V + P++P
Sbjct: 10722 PEVPKEVVP----EKKVPLVVPKKPEAPPAKVP-------EVPKEVVPEKKVAVPKKPEV 10770
Query: 4917 PPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970
PP+ + P P E E P P+ E P + PE P+ P EE
Sbjct: 10771 PPAKVPEVPKKPVLE---EKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEE 10821
Score = 43.5 bits (101), Expect = 0.006
Identities = 40/144 (27%), Positives = 58/144 (40%), Gaps = 18/144 (12%)
Query: 2322 KTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQA----LAPSPPSHPDIFRPGSYTDP 2377
K P+V K P E + P L + ++PPPA+ P P + P P
Sbjct: 9977 KVPEVPKKP--------EEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAP 10028
Query: 2378 YAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCP 2437
A+ P P+ P PE +P P ++VP P+ + TP P EA P
Sbjct: 10029 PAKVPEVPKK--PVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEA--P 10084
Query: 2438 SPVTPRFQSPDPYSRPPSRPQSRD 2461
P P+ + P P P + PQ +
Sbjct: 10085 PPKVPKKREPVPV--PVALPQEEE 10106
Score = 43.1 bits (100), Expect = 0.008
Identities = 45/156 (28%), Positives = 66/156 (42%), Gaps = 18/156 (11%)
Query: 4829 EPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEP 4888
E K +GP EK + K P T K+ A +P K ++ + +E P
Sbjct: 10434 EKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVP-- 10491
Query: 4889 PTQHSYTYNVSNL-DVRQLSAPPPEEPSPPP--SPLAPS--------PASPPTEPLVELP 4937
PT+ + +++ PP ++P PP P AP P PP +P E+P
Sbjct: 10492 PTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKP--EVP 10549
Query: 4938 TEPLAEPPVP-SPLPLASSPESARPKPRARPPEEGE 4972
P P VP + +P PE+ PKP + PPE E
Sbjct: 10550 --PTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPE 10583
Score = 41.6 bits (96), Expect = 0.022
Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 19/166 (11%)
Query: 4283 PQGPPRLPAPPGALSTGPVLGPVHPTPPPSS-PQEPKRPSQ---LPSPSSQLPTEAQLPP 4338
P P +P P PV P PP+ P+ PK+P + + P + P A++P
Sbjct: 9947 PVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPE 10006
Query: 4339 THPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDP-PDNLAETQKPEQSSLVPG 4397
P P P+ P P +V A++ + P P P+ P++ P
Sbjct: 10007 V-PKKPVPEEKVPVPVPKKVEAPPAKVPEV-------PKKPVPEKKVPVPAPKKVEAPPA 10058
Query: 4398 HLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAP 4443
+ +V +++PE +++P P + A K EP+ P
Sbjct: 10059 KVPEVPKKLIPE------EKKPTPVPKKVEAPPPKVPKKREPVPVP 10098
Score = 40.8 bits (94), Expect = 0.038
Identities = 65/278 (23%), Positives = 96/278 (34%), Gaps = 37/278 (13%)
Query: 4702 PDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIP-------LIPRASIPVFPD 4754
P +VP P + + E + R +E R +P ++P +PV P
Sbjct: 10456 PTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPA 10515
Query: 4755 TKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNS 4814
KP P K+P EV V K V E+ +P
Sbjct: 10516 KKPEAP-----PPKVPEAP------KEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVP-- 10562
Query: 4815 YEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLD 4874
E PE+ P E P KE E K P P + V P ++ +
Sbjct: 10563 -EKKVPEAIPPKPESPPPEVPEAP--KEVVPEKKVPAAPP----KKPEVTPVKVPEAPKE 10615
Query: 4875 ILSLLKQESPAPE----PPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPT 4930
++ K P P+ PPT+ V+ + + A PP+ SPPP P
Sbjct: 10616 VVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVF-----EEPE 10670
Query: 4931 EPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968
E +E P + E P P+ P + P +P P + P
Sbjct: 10671 EVALEEPPAEVVEEPEPAAPPQVTVPPK-KPVPEKKAP 10707
Score = 40.8 bits (94), Expect = 0.038
Identities = 38/156 (24%), Positives = 62/156 (39%), Gaps = 10/156 (6%)
Query: 4286 PPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPK 4345
PP++P P + + P PPP P+ P P+++P E ++P P PK
Sbjct: 10522 PPKVPEAPKEVVPEKKV----PVPPPKKPEVP--PTKVPEVPKAAVPEKKVPEAIP--PK 10573
Query: 4346 PQGPTLEPP--PGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVN 4403
P+ P E P P V P A + P P+ E ++ + P +V
Sbjct: 10574 PESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVP 10633
Query: 4404 GQVVPEASQLSIKQEPREEPCALGAQSVKREANGEP 4439
VPE ++++ ++ E +S E EP
Sbjct: 10634 PTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEP 10669
Score = 40.8 bits (94), Expect = 0.038
Identities = 90/394 (22%), Positives = 136/394 (34%), Gaps = 61/394 (15%)
Query: 4619 PPTPPSSLPPTPPPSVQQKMVNGVTPSE------ELGEHPKDA------ASARDSERALR 4666
P PP +P P V +K V V P + ++ E PK+ A + E
Sbjct: 10714 PELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPA 10773
Query: 4667 DTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLG 4726
EV +L P P E E + P+ I P E I EE P
Sbjct: 10774 KVPEVPKKPVLEEKPAVP--VPERAESPPPEVYEEPEEIAPE---EEIAPEEEKPVPVAE 10828
Query: 4727 SGRWEQEDRALSPVIP-----LIPRASIPVF------PDTKPYGALGLEVPG---KLPVT 4772
E+E P +P +IP +PV P +P +E P + P
Sbjct: 10829 ----EEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPP 10884
Query: 4773 TWEKGKGSEVSVMLTVSAAAAKNL--NGVMVAVAELLSMKIPNSYEVLFPESPARAGTEP 4830
K + + A K + + EL +K+P + + P R EP
Sbjct: 10885 PPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERK-PEP 10943
Query: 4831 KKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVL----PGYTLKSQLDILSLLKQESPAP 4886
K+ E K E + P P L++ P ++++ ++ K+E P
Sbjct: 10944 KE-EVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIP 11002
Query: 4887 EPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP-- 4944
EP +++ P EP P P + PP EP PT P+A P
Sbjct: 11003 EPTKVP---------EIKPAIPLPAPEPKPKPEAEVKTIKPPPVEP---EPT-PIAAPVT 11049
Query: 4945 -PVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
PV A +P+ KP+ P +G + P
Sbjct: 11050 VPVVGKKAEAKAPKEEAAKPKG--PIKGVPKKTP 11081
Score = 39.3 bits (90), Expect = 0.11
Identities = 84/391 (21%), Positives = 126/391 (32%), Gaps = 89/391 (22%)
Query: 2050 RKVPAA---DKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRI 2106
RKVPA KAP K +I K ++ E + + TKV ++++K P R
Sbjct: 9163 RKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKI-VPQKPSRT 9221
Query: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166
P Q + PA + S S + + SV P+ E+ +
Sbjct: 9222 PVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEV------SVTVPEVQKEIVTEEKIH 9275
Query: 2167 VPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEF 2226
V + P P P P P P P +PP P P E
Sbjct: 9276 VAISKRVEPP-------PKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEK 9328
Query: 2227 HTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALE 2286
P P+ +P+ P P+ P + VPE P P + ++A
Sbjct: 9329 KPVP--VPKKEPAAP-----PKVPEVPKKPVPEEK------------IPVPVAKKKEA-- 9367
Query: 2287 VKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLG 2346
PP K P+V K +T + Q
Sbjct: 9368 --------------PP------------------AKVPEVQKGVVTEEKITIVTQ----- 9390
Query: 2347 LRPQEPPPAQALAPS---PPSHPDIFRPGSYTDPYAQPPLTPR-PQPPPPESCCALPPRS 2402
R + PPPA P P + R P PP P P+ P PE A+P
Sbjct: 9391 -REESPPPAVPEIPKKKVPEERKPVPRKEEEVPP---PPKVPALPKKPVPEEKVAVPV-- 9444
Query: 2403 LPSDPFSRVPASPQSQSSSQSPLTPRPLSAE 2433
P ++ P+++ S ++ + + AE
Sbjct: 9445 ----PVAKKAPPPRAEVSKKTVVEEKRFVAE 9471
Score = 38.5 bits (88), Expect = 0.19
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 4904 RQLSAPPPEEPSPPPSP------LAPSPASPPTEPLVELPTEPLAEPPVPSPLP--LASS 4955
++ APP + P P P L P PP + E+P +P+ E VP P+P + +
Sbjct: 9969 KKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAP 10028
Query: 4956 PESARPKPRARPPEE 4970
P P+ PE+
Sbjct: 10029 PAKVPEVPKKPVPEK 10043
Score = 38.5 bits (88), Expect = 0.19
Identities = 27/109 (24%), Positives = 43/109 (39%), Gaps = 10/109 (9%)
Query: 4880 KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPL--------APSPASPPTE 4931
K+ PA P V L ++ PP + P P P+ P P
Sbjct: 9971 KEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPA 10030
Query: 4932 PLVELPTEPLAEP--PVPSPLPLASSPESARPKPRARPPEEGEDSRPPR 4978
+ E+P +P+ E PVP+P + + P P+ PEE + + P+
Sbjct: 10031 KVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPK 10079
Score = 37.0 bits (84), Expect = 0.55
Identities = 39/163 (23%), Positives = 59/163 (36%), Gaps = 15/163 (9%)
Query: 4281 PRPQGPP-RLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPT 4339
P+P+ PP + P ++ V P P++P + P + P P + P P
Sbjct: 10656 PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPE 10715
Query: 4340 HPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQK---PEQSSLVP 4396
P P+ P P +V + P PP + E K PE+ VP
Sbjct: 10716 LPPVKVPEVPKEVVPEKKVPLVVPK----------KPEAPPAKVPEVPKEVVPEKKVAVP 10765
Query: 4397 GHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEP 4439
+V VPE + + +E P A+S E EP
Sbjct: 10766 -KKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEP 10807
Score = 37.0 bits (84), Expect = 0.55
Identities = 38/176 (21%), Positives = 66/176 (37%), Gaps = 34/176 (19%)
Query: 4273 PLQELGAGPRPQGPPRLPAP----------PGALSTGPVLGPVH--------------PT 4308
P E+ P P PP++ P P ++ P L PV P
Sbjct: 10677 PPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPL 10736
Query: 4309 PPPSSPQEPKRPSQLPS-PSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLAD 4367
P P+ P P+++P P +P + P P P + P + P A + +
Sbjct: 10737 VVPKKPEAP--PAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPE 10794
Query: 4368 TLFSKGLGPWDPPDNLAETQK--PEQSSLVPGHLDQVNGQVVPEASQLSIKQEPRE 4421
S ++ P+ +A ++ PE+ VP V + PE ++ +EP++
Sbjct: 10795 RAESPPPEVYEEPEEIAPEEEIAPEEEKPVP-----VAEEEEPEVPPPAVPEEPKK 10845
Score = 36.6 bits (83), Expect = 0.71
Identities = 40/166 (24%), Positives = 66/166 (39%), Gaps = 29/166 (17%)
Query: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSS-PQEPKRP-----------SQLPSPSS 4328
P P P +P P PV P PP+ P+ PK+P ++ +P +
Sbjct: 9999 PPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPA 10058
Query: 4329 QLP--TEAQLPPTHPGTPKPQGPTLEPP-------PGRVSPAAAQLADTLFSKGLGPWDP 4379
++P + +P TP P+ PP P V A Q + LF + + P +
Sbjct: 10059 KVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEE 10118
Query: 4380 PDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQE---PREE 4422
E PE+ ++P +V+PE ++ ++E P EE
Sbjct: 10119 VLPEEEEVLPEEEEVLP-----EEEEVLPEEEEIPPEEEEVPPEEE 10159
Score = 36.2 bits (82), Expect = 0.93
Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 21/159 (13%)
Query: 4283 PQGPPRLPAPPGALSTGPVLGPVHPTPPPSS-PQEPKRP-----------SQLPSPSSQL 4330
P P +P P PVL P PPP+ P+ PK+P ++ +P +++
Sbjct: 9975 PAKVPEVPKKPE--EKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKV 10032
Query: 4331 PTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWD---PPDNLAETQ 4387
P + P P P +E PP +V +L P PP + + +
Sbjct: 10033 PEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKR 10092
Query: 4388 KPEQSSLVPGHLDQV--NGQVVPEASQLSIKQE--PREE 4422
+P + ++V ++VPE L ++E P EE
Sbjct: 10093 EPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEE 10131
Score = 36.2 bits (82), Expect = 0.93
Identities = 35/150 (23%), Positives = 60/150 (40%), Gaps = 29/150 (19%)
Query: 4841 KEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSN 4900
KE+ K P+ P +++ +LP + ++L + E P EP ++ +
Sbjct: 10204 KEEAPPAKVPEV-PKKVEEKRIILP-----KEEEVLPVEVTEEPEEEPISEEEIPEEPPS 10257
Query: 4901 LDVRQLSAPP----------PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPL 4950
++ + APP PE P+P P + +PP + ++P E + P
Sbjct: 10258 IEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVE----APPAKVSKKIPEEKVPVPVQKKEA 10313
Query: 4951 PLASSPESAR---------PKPRARPPEEG 4971
P A PE + PK A PP +G
Sbjct: 10314 PPAKVPEVPKKVPEKKVLVPKKEAVPPAKG 10343
Score = 35.8 bits (81), Expect = 1.2
Identities = 74/342 (21%), Positives = 123/342 (35%), Gaps = 47/342 (13%)
Query: 4685 HNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHL----------GSGRWEQED 4734
+ + E ++++ + +S + VPA PE ++AP P + + R +E+
Sbjct: 9144 YQEREVIQVQKEVYEESHERKVPAKVPE----KKAPPPPKVIKKPVIEKIEKTSRRMEEE 9199
Query: 4735 RALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEK----------GKGSEVSV 4784
+ +P + + +P P P +EV K+P +K +E V
Sbjct: 9200 KVQVTKVPEVSKKIVPQKPSRTPVQEEVIEV--KVPAVHTKKMVISEEKMFFASHTEEEV 9257
Query: 4785 MLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEP----KKGEAEGPG- 4839
+TV + + + VA ++ P L PE PA P KK E P
Sbjct: 9258 SVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPEL-PEKPAPEEVAPVPIPKKVEPPAPKV 9316
Query: 4840 ---GKEKGLEGKSPDTGPDWLKQFDAVLPGYTLK----SQLDILSLLKQESPAPEPPTQH 4892
K+ E K P P +P K ++ + K+E+P + P
Sbjct: 9317 PEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQ 9376
Query: 4893 SYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPL 4952
+ + EE PP P P P V E + PP LP
Sbjct: 9377 KGVVTEEKITI----VTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPK 9432
Query: 4953 ASSPES--ARPKPRAR--PPEEGEDSRPPRLKKWKGVRWKRL 4990
PE A P P A+ PP E S+ +++ + V ++L
Sbjct: 9433 KPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKL 9474
Score = 35.8 bits (81), Expect = 1.2
Identities = 28/90 (31%), Positives = 33/90 (36%), Gaps = 16/90 (17%)
Query: 4283 PQGPPRLPAPPGALSTGPVLGPVHPTPP-PSSPQEPKRPSQLPSPSSQLPT---EAQLPP 4338
P P LP P PV P PP P P+ PK+P +P +P E PP
Sbjct: 9285 PPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKP--VPEEKKPVPVPKKEPAAPP 9342
Query: 4339 THPGTPK----------PQGPTLEPPPGRV 4358
P PK P E PP +V
Sbjct: 9343 KVPEVPKKPVPEEKIPVPVAKKKEAPPAKV 9372
Score = 35.8 bits (81), Expect = 1.2
Identities = 84/391 (21%), Positives = 136/391 (34%), Gaps = 48/391 (12%)
Query: 4611 LTKNNLSNPPTPPSSLPPTPPPSVQQKMV----NGVTPSEELGEHPKDAASARDSERALR 4666
+TK P + +P P V ++ V V P + E PK+ + E
Sbjct: 9855 ITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKEL----EPEEVAF 9910
Query: 4667 DTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPA------SSPESILGEEAP 4720
+ V ++ + E+ + +E+ + + +VP P + EE
Sbjct: 9911 EEEVVTHVEEYLV-------EEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKK 9963
Query: 4721 RFPHLGSGRWEQEDRALSPVIPLIPRASIPVF--PDTKPYGALGLEVPGK------LPVT 4772
P + ++ A P +P P +PV KP A EVP K +PV
Sbjct: 9964 PVP---VPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVP 10020
Query: 4773 TWEKGKGSEVSVM-LTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPK 4831
+K + V + K + E K+P + L PE + PK
Sbjct: 10021 VPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEK-KPTPVPK 10079
Query: 4832 KGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQ 4891
K EA P +K + P P L Q + VL + + ++L ++E PE +
Sbjct: 10080 KVEAPPPKVPKK----REPVPVPVALPQEEEVLFEEEIVPEEEVLP--EEEEVLPE---E 10130
Query: 4892 HSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLP 4951
+ + PP EE PP P E + E P +P VP P P
Sbjct: 10131 EEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPE----EEEFVPEEEVLPEVKPKVPVPAP 10186
Query: 4952 LASSPESARPKPRARP-PEEGEDSRPPRLKK 4981
+ + K P EE ++ P + K
Sbjct: 10187 VPEIKKKVTEKKVVIPKKEEAPPAKVPEVPK 10217
Score = 35.8 bits (81), Expect = 1.2
Identities = 45/182 (24%), Positives = 69/182 (37%), Gaps = 46/182 (25%)
Query: 4281 PRPQGPP-RLPAPPGAL-------STGPVLGPVHPTPPPSSPQE-----------PKRPS 4321
P+P+ PP +P P + + P V P P +P+E PK+P
Sbjct: 10572 PKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPE 10631
Query: 4322 QLPSPSSQLP----TEAQLPPTHPGTPKPQGP-----------TLEPPPGRV----SPAA 4362
P+ ++P E ++P P PKP+ P LE PP V PAA
Sbjct: 10632 VPPTKVPEVPKVAVPEKKVPEAIP--PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAA 10689
Query: 4363 AQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEAS-QLSIKQEPRE 4421
K + P+ A ++ L P + +V +VVPE L + ++P
Sbjct: 10690 PPQVTVPPKKPV-----PEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA 10744
Query: 4422 EP 4423
P
Sbjct: 10745 PP 10746
Score = 35.8 bits (81), Expect = 1.2
Identities = 51/238 (21%), Positives = 92/238 (38%), Gaps = 48/238 (20%)
Query: 4155 PQQPMLERPMQN-NTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRH 4213
P++P E+ ++ P+PP P P P + + QL+A + + + PQ+
Sbjct: 10863 PKEPEPEKVIEKPKLKPRPPPPPPAP------PKEDVKEKIFQLKAIPKKKVPEKPQVPE 10916
Query: 4214 ---LSPQQ----QQQLQALLMQRQLQQSQAV------RQTPPYQEPGTQTSPLQGLLGCQ 4260
L+P + +++++ LL +R+ + + V R+ P +EP + L+ + +
Sbjct: 10917 KVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVK--K 10974
Query: 4261 PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRP 4320
P + P+ PP P P + V P P+ E K
Sbjct: 10975 PAV-------------------PEPPP--PKPVEEVEVPTVTKRERKIPEPTKVPEIKPA 11013
Query: 4321 SQLPSPSSQLPTEAQL-----PPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKG 4373
LP+P + EA++ PP P P P G+ + A A + KG
Sbjct: 11014 IPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKG 11071
Score = 35.8 bits (81), Expect = 1.2
Identities = 47/162 (29%), Positives = 60/162 (37%), Gaps = 33/162 (20%)
Query: 2143 LKPPAGSVPGPDSPGELF---------LKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTA- 2192
+K PA P P P E K+P P +VP P PA +P+ P A
Sbjct: 10972 VKKPAVPEPPPPKPVEEVEVPTVTKRERKIPE--PTKVPEIKPAIPLPAPEPKPK-PEAE 11028
Query: 2193 -----PPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQP-STPDPFLK 2246
PP P P+P AP P++G + A P E P G + P TP P
Sbjct: 11029 VKTIKPPPVEPEPTPIAAPVTVPVVGKKAE--AKAPKEEAAKPKGPIKGVPKKTPSPIEA 11086
Query: 2247 PRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVK 2288
R PG GG K + PF KA+ +K
Sbjct: 11087 ERRKL--------RPGSGGEKPPD----EAPFTYQLKAVPLK 11116
Score = 35.0 bits (79), Expect = 2.1
Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 3/66 (4%)
Query: 4282 RPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPS--QLPS-PSSQLPTEAQLPP 4338
+P+ PP P + P L P P PPP+ P+E + QL + P ++P + Q+P
Sbjct: 10857 KPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPE 10916
Query: 4339 THPGTP 4344
TP
Sbjct: 10917 KVELTP 10922
Score = 34.7 bits (78), Expect = 2.7
Identities = 40/126 (31%), Positives = 48/126 (38%), Gaps = 19/126 (15%)
Query: 948 PPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILP-PSPG 1006
PP + P + P P S A L SP P + P PV + P PSP
Sbjct: 254 PPRIPPKPKSRSP-------TPPSIAAKAQLARQQSPSPIRH--SPSPVRHVRAPTPSPV 304
Query: 1007 SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSD 1066
V PA+ I P+ SPLL +Q S A VP P G V S
Sbjct: 305 RSVSPAARISTSPIRSVRSPLLMRK--------TQASTVATGPEVPPPWKQEGYVAS-SS 355
Query: 1067 EAELHE 1072
EAE+ E
Sbjct: 356 EAEMRE 361
Score = 34.7 bits (78), Expect = 2.7
Identities = 35/148 (23%), Positives = 62/148 (41%), Gaps = 28/148 (18%)
Query: 4282 RPQGPP-RLP-APPGALSTGPVLGPVHPTPPPSS-PQEPKRPSQLPSPSSQLPTEAQLPP 4338
+P+ PP ++P P + V P P PP+ P+ PK+P P+ +P A+ PP
Sbjct: 10741 KPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPP 10800
Query: 4339 THPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGH 4398
P + P ++P + + P +AE ++PE + P
Sbjct: 10801 ----------PEVYEEPEEIAPEEEIAPEE---------EKPVPVAEEEEPE---VPPPA 10838
Query: 4399 LDQVNGQVVPEASQLSIKQ---EPREEP 4423
+ + +++PE IK+ P +EP
Sbjct: 10839 VPEEPKKIIPEKKVPVIKKPEAPPPKEP 10866
Score = 34.7 bits (78), Expect = 2.7
Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 12/98 (12%)
Query: 4304 PVHPTPPPSSPQE-------PKRPSQLPSPSSQLPTEAQLP-PTHPGTPKPQG--PTLEP 4353
P P PPP P E KR ++P P+ + +P P PKP+ T++P
Sbjct: 10975 PAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKP 11034
Query: 4354 PP--GRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389
PP +P AA + + K P + A+ + P
Sbjct: 11035 PPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGP 11072
Score = 34.3 bits (77), Expect = 3.5
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 10/61 (16%)
Query: 4905 QLSAPPPEEP-SPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
+L PP+ P S P P P A PP E P+ PP+P LP +PE +P P
Sbjct: 8929 KLELKPPDIPDSRVPIPTMPIRAVPPEE------IPPVVAPPIPLLLP---TPEEKKPPP 8979
Query: 4964 R 4964
+
Sbjct: 8980 K 8980
Score = 33.9 bits (76), Expect = 4.6
Identities = 42/161 (26%), Positives = 60/161 (37%), Gaps = 26/161 (16%)
Query: 2333 PRASQVEPQSPGLGLRPQEPPPAQAL-APSPPSHPDIFRPGSYTDPYAQPPLTPR-PQPP 2390
P +VEP +P + P++P P + P P P A PP P P+ P
Sbjct: 9304 PIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEP------------AAPPKVPEVPKKP 9351
Query: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQ--SPLTPR---PLSAEAFCPSPVTPRFQ 2445
PE +P P ++VP + + + + +T R P A P P +
Sbjct: 9352 VPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEER 9411
Query: 2446 SPDPYSRPPSRPQSRDPFAPLHKPPRPQ-----PPEVAFKA 2481
P P P + P P K P P+ P VA KA
Sbjct: 9412 KPVPRKEEEVPPPPKVPALP--KKPVPEEKVAVPVPVAKKA 9450
Score = 33.5 bits (75), Expect = 6.0
Identities = 61/290 (21%), Positives = 107/290 (36%), Gaps = 51/290 (17%)
Query: 4732 QEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAA 4791
Q + + P +P IP+ +P P + P K+P + +V+V + V+
Sbjct: 9390 QREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKK 9449
Query: 4792 AAKNLNGVM---------VAVAELLSMKIPNSYEVLFPESPAR---AGTEPKKGEAEGPG 4839
A V E LS +P EV E A + +E ++G +
Sbjct: 9450 APPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVY 9509
Query: 4840 GKEKGLEGKSPD-TGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNV 4898
+E+ E + + T + +++ + Y ++ +L I+S + PA Q
Sbjct: 9510 REEEREEEEEAEVTEYEVMEEPEE----YVVEEKLHIISKRVEAEPAEVTERQEKKIVLK 9565
Query: 4899 SNLDVRQLSAPPPEEPSPP---------PSPLAPSPASPPTEPLVELPTEPLAEPPVP-- 4947
+ + PP + P P P+P+ PP + + E P +P+ E VP
Sbjct: 9566 PKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPK-VPEEPKKPVPEKKVPPK 9624
Query: 4948 -----SPLP----------------LASSPESARPKPRARPPEEGEDSRP 4976
PLP L + + P P+AR PEE + + P
Sbjct: 9625 VIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAP-PKARVPEEPKRAVP 9673
Score = 33.1 bits (74), Expect = 7.9
Identities = 34/139 (24%), Positives = 55/139 (39%), Gaps = 16/139 (11%)
Query: 758 EPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL-SPQAEGPHLSPQPEE---------LHLS 807
EP P A EPH+ P+ +P + P E H+ + +G H+S Q ++ +H+
Sbjct: 748 EPPQRP-ASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQIKKTTDLTTERLVHVD 806
Query: 808 --PQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
P+T PH + P+ E + + + + + E S S + P
Sbjct: 807 KRPRTASPHFT---VSKISVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPT 863
Query: 866 KPPEEPGQCPAPEELPLFP 884
P E P LP FP
Sbjct: 864 VKPSETRVRAEPTPLPQFP 882
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 170 bits (430), Expect = 4e-41
Identities = 127/426 (29%), Positives = 160/426 (37%), Gaps = 73/426 (17%)
Query: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEA 432
+PP+ G+ P P P+GG+ QP+ P P P GK PQ
Sbjct: 39 APPQGGNKPQGPPSPPGKPQGPPPQGGN----QPQGPPP------PPGK------PQGPP 82
Query: 433 PLNEEMPLLPPPEESPLSPPPE-----------ESPTSPPPEASRL---SPPPEELPASP 478
P P PPP P PPP+ P PPP+ PPP P P
Sbjct: 83 PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 142
Query: 479 LPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSP 538
P+ P PPP P PPP+ S SP P+ PP + P
Sbjct: 143 PPQG-------GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP 195
Query: 539 PPEASPLSPPFE--ESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596
PP P PP + P PPP P PPP+ S +S SPP + P PPP+
Sbjct: 196 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS----QSARSPPGK--PQGPPPQG 249
Query: 597 SRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL 656
+ PPP P PPP+ + P PPP P PPP+
Sbjct: 250 G------NQPQGPPPPPGKPQGPPPQGG-------NKPQGPPPPGKPQGPPPQGGS---- 292
Query: 657 PVVSRLSPPPEESPLSPPPE--ESPTSPPPEASR-LSPPPE--DSPTSPPPEDSPASPPP 711
SR S P P PPP+ P PPP + PPP+ + P PPP P PPP
Sbjct: 293 --KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 350
Query: 712 EDSLMSLPLEESPLLPL--PEEPQLCPRSEGPHLSPRPEEPHLSP--RPEEPHLSPQAEE 767
+ S P P P++ P+ P P++P P +P+ P PQ
Sbjct: 351 QGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGR 410
Query: 768 PHLSPQ 773
P PQ
Sbjct: 411 PSRPPQ 416
Score = 149 bits (376), Expect = 8e-35
Identities = 136/441 (30%), Positives = 167/441 (37%), Gaps = 81/441 (18%)
Query: 436 EEMPLLPPPEESPLSPPPEESPTSPP-PEASRLSPPPE--ELPASPLPEALHLSRPLEES 492
EE P L P P PP P PPP+ P P
Sbjct: 26 EESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP-------------- 71
Query: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA----SPLSPP 548
PPP P PPP+ P PP PP P PPP+ SP SPP
Sbjct: 72 ---PPPPGKPQGPPPQGG------NKPQGPP---PPG----KPQGPPPQGDKSRSPRSPP 115
Query: 549 FEESPLSPPPE--ELPTSPPPEASR-LSPPPE--ESPMSPPPEESPMSPPPEA-----SR 598
P PPP+ P PPP + PPP+ P PPP P PPP+ S
Sbjct: 116 --GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSS 173
Query: 599 LFPPFEESPLSPPPE--ESPLSPPPEASR-LSPPPE--DSPMSPPPEESPMSPPPEVSRL 653
PP P PPP+ P PPP + PPP+ + P PPP P PPP+
Sbjct: 174 RSPP--GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231
Query: 654 SPLPVVSRLSPPPEESPLSPPPE--ESPTSPPPEASR-LSPPPE--DSPTSPPPEDSPAS 708
S S SPP + P PPP+ P PPP + PPP+ + P PPP P
Sbjct: 232 SQ----SARSPPGK--PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 285
Query: 709 PPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP 768
PPP+ S P P PQ + +GP P P +P P P+ + PQ P
Sbjct: 286 PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP--PPPPGKPQ-GPPPQGGN-KPQGPPP 341
Query: 769 HLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQ--PEELHLSPQTEEPHLSPVPEEPCLSP 826
PQ P+ S A P PQ P++ +PQ P P++P P
Sbjct: 342 PGKPQGPP------PQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395
Query: 827 --QPEESHLSPQSEEPCLSPR 845
QP+ PQ P P+
Sbjct: 396 AGQPQGPPRPPQGGRPSRPPQ 416
Score = 142 bits (358), Expect = 9e-33
Identities = 136/464 (29%), Positives = 169/464 (36%), Gaps = 89/464 (19%)
Query: 524 EESPPSPALETPLSPPPEAS--PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPM 581
+E PS P PP+ P PP SPP + P PPP+ P
Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPP------SPPGK--PQGPPPQGGNQPQGP----- 71
Query: 582 SPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP--PEDSPMSPPP 639
PPP P PPP+ P PPP P PPP+ + P P P PPP
Sbjct: 72 -PPPPGKPQGPPPQGGN-------KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 123
Query: 640 E--ESPMSPPPEVSRLSPLPVVSRLSPPPE--ESPLSPPPEESPTSPPPEA---SRLSPP 692
+ P PPP P PPP+ P PPP P PPP+ SR S
Sbjct: 124 QGGNQPQGPPP--------PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRS 175
Query: 693 PEDSPTSPPPE--DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEP 750
P P PPP+ + P PPP P P PQ + +GP P P +P
Sbjct: 176 PPGKPQGPPPQGGNQPQGPPPP-----------PGKPQGPPPQGGNKPQGP---PPPGKP 221
Query: 751 HLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQT 810
P P+ + S A P PQ P P+ P P G P P+
Sbjct: 222 Q-GPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP---PPPPGKPQGPPPQG------G 271
Query: 811 EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSP-RPEKPPE 869
+P P P +P P P+ S S P P+ + + PP P +P+ PP
Sbjct: 272 NKPQGPPPPGKP-QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 330
Query: 870 EPG---QCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLS 926
+ G Q P P P PPP S S A S PG+P P + +
Sbjct: 331 QGGNKPQGPPPPGKPQGPPPQGGSKS----RSARSPPGKPQ----------GPPQQEGNN 376
Query: 927 PQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPE 970
PQ PP P P APPA P G P G + P+
Sbjct: 377 PQGPPPPAGGNPQQP----QAPPAGQPQGPPRPPQGGRPSRPPQ 416
Score = 114 bits (285), Expect = 3e-24
Identities = 119/455 (26%), Positives = 153/455 (33%), Gaps = 99/455 (21%)
Query: 588 SPMSPPPEASRLFPPFEESPLSPP-PEESPLSPPPEASRLS---PPPEDSPMSPPPE--E 641
+P PP+ P PP P P PPP+ PPP P PPP+
Sbjct: 35 NPQGAPPQGGN-------KPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 87
Query: 642 SPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLS---PPPEDSPT 698
P PPP P P + SP SPP + P PPP+ PPP P
Sbjct: 88 KPQGPPPPGKPQGPPPQGDK-----SRSPRSPPGK--PQGPPPQGGNQPQGPPPPPGKPQ 140
Query: 699 SPPPE--DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP 756
PPP+ + P PPP P +PQ P P+ + S
Sbjct: 141 GPPPQGGNKPQGPPP-----------------PGKPQ----------GPPPQGDNKSRSS 173
Query: 757 EEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLS 816
P PQ P QP+ P P G P P+ +P
Sbjct: 174 RSPPGKPQGPPPQGGNQPQGP------------PPPPGKPQGPPPQG------GNKPQGP 215
Query: 817 PVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSP-RPEKPPEEPGQCP 875
P P +P P P+ + S + P P+ + + PP P +P+ PP + G P
Sbjct: 216 PPPGKP-QGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 274
Query: 876 APEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL 935
PPPG+P P G PP P P + PQ PP P
Sbjct: 275 QGP-----PPPGKPQGPPPQGGSKSRSSRSPPGKPQ------GPPPQGGNQPQGPPPPPG 323
Query: 936 ----PPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCT 991
PPP PP P G P G SP P PP+
Sbjct: 324 KPQGPPPQGGNKPQGPPPPGKPQGPP--PQGGSKSRSARSPPGKP------QGPPQQEGN 375
Query: 992 DPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSP 1026
+P+ PP P+ G+P P +P +P P P
Sbjct: 376 NPQGPPP----PAGGNPQQPQAPPAGQPQGPPRPP 406
Score = 96.3 bits (238), Expect = 8e-19
Identities = 126/468 (26%), Positives = 158/468 (33%), Gaps = 109/468 (23%)
Query: 2175 DPFGLAPAYPLEPRFPTAPPTYPPYPSPTGA-----PAQPPMLGASSRPGAGQPGEFHTT 2229
+P G P +P+ P +PP P P P G P PP P G +
Sbjct: 35 NPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ-GPP 93
Query: 2230 PPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKK 2289
PPG P+ P D PR P P+ P GG ++P PPP G+ +
Sbjct: 94 PPGKPQGPPPQGDKSRSPRSPP----GKPQGPPPQGG--NQPQGPPPPPGKPQ------- 140
Query: 2290 EELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRP 2349
GPP P G +PQ P +P
Sbjct: 141 ----------GPP-------PQGGN------------------------KPQGPPPPGKP 159
Query: 2350 QEPPPA----QALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCC---ALPPRS 2402
Q PPP + SPP P P P PP +PQ PPP+ PP
Sbjct: 160 QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 219
Query: 2403 LPSDPFSRVPASPQSQSSSQSPLTP--RPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSR 2460
P P PQ + SQS +P +P P + Q P P PP +PQ
Sbjct: 220 KPQGP------PPQGDNKSQSARSPPGKPQGP----PPQGGNQPQGPPP---PPGKPQGP 266
Query: 2461 DPFA---PLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPN 2517
P P PP +P + GS + +S G P P P G P G PP
Sbjct: 267 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPP--PQG---GNQPQGPPP- 320
Query: 2518 FVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHG----INSHFGPGPTLG 2573
PG G P PQ +P PP +P PPP G ++ PG G
Sbjct: 321 ---PPGKPQ--GPP-------PQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQG 368
Query: 2574 KPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621
PQ G+P P + G+ G P RPP P P
Sbjct: 369 PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG--PPRPPQGGRPSRP 414
Score = 96.3 bits (238), Expect = 8e-19
Identities = 111/413 (26%), Positives = 144/413 (34%), Gaps = 80/413 (19%)
Query: 665 PPE--ESPLSPP-PEESPTSPPPEASRLS---PPPEDSPTSPPPE--DSPASPPPEDSLM 716
PP+ P PP P P PPP+ PPP P PPP+ + P PPP
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----- 94
Query: 717 SLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776
P +PQ GP P + S P P PQ P QP+
Sbjct: 95 ------------PGKPQ------GP-----PPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 131
Query: 777 PCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQ 836
P P G P P+ +P P P +P P P+ + S
Sbjct: 132 P------------PPPPGKPQGPPPQG------GNKPQGPPPPGKP-QGPPPQGDNKSRS 172
Query: 837 SEEPCLSPRPEESHLSPELEKPPLSP-RPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895
S P P+ + + PP P +P+ PP + G P PPPG+P P
Sbjct: 173 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP-----PPPGKPQGPPPQ 227
Query: 896 GE----PALSEPGEPPLSPL--------PEELPLSPSGEP---SLSPQLMPPDPLPPPLS 940
G+ A S PG+P P P P P G P PQ PP P
Sbjct: 228 GDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 287
Query: 941 PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMI 1000
P + + + SP G+ + P +G + P+ P P P PPP+ P+ PP
Sbjct: 288 PQGGSKSRSSRSPPGKPQGP-PPQGGNQPQGPPPPP--GKPQGPPPQGG-NKPQGPPPPG 343
Query: 1001 LPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPS 1053
P P G S P P Q PQ PP P P + P+
Sbjct: 344 KPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA 396
Score = 94.4 bits (233), Expect = 3e-18
Identities = 123/443 (27%), Positives = 146/443 (32%), Gaps = 66/443 (14%)
Query: 2128 SPTTPAGLSTSADGFLKPPAGSVP-GPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLE 2186
SP+ AG A P G+ P GP SP PQ P P G P
Sbjct: 28 SPSLIAGNPQGAP----PQGGNKPQGPPSPPG-----KPQGPPPQGGNQPQGPPPP---- 74
Query: 2187 PRFPTAPPTY----PPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPD 2242
P P PP P P P G P PP G SR PG+ PP P
Sbjct: 75 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP 134
Query: 2243 PFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPP 2302
P KP+ P P+ P G PPP G+++ S S PP
Sbjct: 135 PPGKPQGPPPQGGNKPQGPPPPGKPQ-----GPPPQGDNK------------SRSSRSPP 177
Query: 2303 NLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPP----AQAL 2358
P G G P K P +PQ P +PQ PPP
Sbjct: 178 GKPQGPPPQGGNQPQG---PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQS 234
Query: 2359 APSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQ 2418
A SPP P P P PP +PQ PPP+ P P P Q
Sbjct: 235 ARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG-----GNKPQGPPPPGKPQGPPPQ 289
Query: 2419 SSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVA 2478
S+S + P P + Q P P PP +PQ P +KP P PP
Sbjct: 290 GGSKSRSSRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQGG-NKPQGPPPPGKP 345
Query: 2479 FKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTF 2538
+ + P P GP + P G PP P G +P +
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQGPP-QQEGNNPQGPPP-----PAGG------NPQQPQA 393
Query: 2539 PQAVGEPSLKPPVPQPGLP--PP 2559
P A G+P P PQ G P PP
Sbjct: 394 PPA-GQPQGPPRPPQGGRPSRPP 415
Score = 84.7 bits (208), Expect = 2e-15
Identities = 130/478 (27%), Positives = 156/478 (32%), Gaps = 118/478 (24%)
Query: 2511 PSGQPPNFVRSPGTGAFVGTPSPM---RFTFPQAVGEPSLKPPVP-QPGLPPPHGINSHF 2566
P G PP P G PSP + PQ +P PP P +P PPP G N
Sbjct: 36 PQGAPPQGGNKPQ-----GPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 90
Query: 2567 GPGPTLGKPQST--NYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGS 2624
GP P GKPQ + P G P GP G P PP PP P G
Sbjct: 91 GPPPP-GKPQGPPPQGDKSRSPRSPPGKPQGPPPQG-----GNQPQGPPP--PPGKPQGP 142
Query: 2625 LPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGT-QDPGMSGLSQTELEKQRQR 2683
P G ++ G P + + P G S ++ PG Q P G +Q +
Sbjct: 143 PP---QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ------- 192
Query: 2684 QRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQ 2743
GPP G +P P +G P
Sbjct: 193 ---------------------GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG--D 229
Query: 2744 DKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAP 2803
+KS PP K GP G+ P PPPP P GG++ Q P
Sbjct: 230 NKSQSARSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGPPPQ-----GGNKP--QGPP 278
Query: 2804 YPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPG 2863
PG + Q Q + + S R P P P+ G Q G P P
Sbjct: 279 PPG-------KPQGPPPQGGSKSRSSRSPPGK--PQGPPPQGGNQPQGPP--------PP 321
Query: 2864 PGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPG--QGPPQRPRFYPVSEDPHRLAPEGL 2921
PG+P P Q G P G P PG QGPP P+G
Sbjct: 322 PGKPQGPPP------------QGGNKPQGPPPPGKPQGPP----------------PQGG 353
Query: 2922 RGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKG-PTLPTGLELVNRPPSSTELGRPNP 2978
+ PP KP PP E NN P P G P P PP+ G P P
Sbjct: 354 SKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP------QAPPAGQPQGPPRP 405
Score = 84.3 bits (207), Expect = 3e-15
Identities = 124/462 (26%), Positives = 148/462 (32%), Gaps = 116/462 (25%)
Query: 2337 QVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ-------PPLTPRPQP 2389
Q P PG +PQ PPP P P P PG P Q PP +PQ
Sbjct: 48 QGPPSPPG---KPQGPPPQGGNQPQGPPPP----PGKPQGPPPQGGNKPQGPPPPGKPQG 100
Query: 2390 PPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDP 2449
PPP+ + PRS P P P Q +Q P P P + Q P P
Sbjct: 101 PPPQGDKSRSPRSPPGKP-----QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 155
Query: 2450 YSRPPSRP-----QSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG 2504
+P P +SR +P KP P P GG P P G
Sbjct: 156 PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ----------------GGNQPQGPPPPPG 199
Query: 2505 ELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGE---PSLKPPVPQPGLPPPHG 2561
+ P G PP P G P P + P G+ S + P +P PPP G
Sbjct: 200 K-----PQGPPPQGGNKPQ-----GPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQG 249
Query: 2562 INSHFGPGPTLGKPQSTNYTVATGNF----HPSGSPLG--PSSGSTGESYGLSPLRPPSV 2615
N GP P GKPQ GN P G P G P GS S S
Sbjct: 250 GNQPQGPPPPPGKPQGP--PPQGGNKPQGPPPPGKPQGPPPQGGSKSRS---------SR 298
Query: 2616 LPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPG-TQDPGMSGLSQ 2674
PP P G P G +Q G P K + P G+ PG Q P G S+
Sbjct: 299 SPPGKPQGPPP---QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK 355
Query: 2675 TELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSR 2734
+ + + GPP G P P
Sbjct: 356 S----------------------------RSARSPPGKPQGPPQQEGNNPQGP------- 380
Query: 2735 GQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPP 2776
P AG + P + +G GP P R SRPP
Sbjct: 381 --PPPAGGNPQQ-----PQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 79.0 bits (193), Expect = 1e-13
Identities = 133/510 (26%), Positives = 172/510 (33%), Gaps = 134/510 (26%)
Query: 2441 TPRFQSPDPYSRPP---SRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAA 2497
+P + +P PP ++PQ P +P KP P P GG
Sbjct: 28 SPSLIAGNPQGAPPQGGNKPQG--PPSPPGKPQGPPPQ----------------GGNQPQ 69
Query: 2498 LPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP--QPG 2555
P P G+ P G PP P G P P + P G+ S P P +P
Sbjct: 70 GPPPPPGK-----PQGPPPQGGNKPQ-----GPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 119
Query: 2556 LPPPHGINSHFGPGPTLGKPQSTNYTVATGNF----HPSGSPLGPSSGSTGESYGLSPLR 2611
PPP G N GP P GKPQ GN P G P GP +S
Sbjct: 120 GPPPQGGNQPQGPPPPPGKPQGP--PPQGGNKPQGPPPPGKPQGPPPQGDNKSRS----- 172
Query: 2612 PPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPG-TQDPGMS 2670
S PP P G P G +Q G P K + P G+ PG Q P
Sbjct: 173 --SRSPPGKPQGPPP---QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 227
Query: 2671 GLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFE 2730
G ++++ + + Q Q + GPP G +P P
Sbjct: 228 GDNKSQSARSPPGK-------PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 280
Query: 2731 QLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQ 2790
+G P G++ +SS PP K GP G+ P PPPP P
Sbjct: 281 GKPQGPPPQGGSKSRSS--RSPPGKPQGPPPQGGNQPQ----GPPPPPGKPQGPPPQ--- 331
Query: 2791 LVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQAL 2850
GG++ Q P PG P P P+ G ++
Sbjct: 332 --GGNKP--QGPPPPGK------------------------------PQGPPPQGGSKSR 357
Query: 2851 GSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVS 2910
S R P PG+ P GP Q Q+G P G P P G PQ+P+ P
Sbjct: 358 -------SARSP-PGK----PQGPPQ--------QEGNNPQGPPPPAGGNPQQPQAPPAG 397
Query: 2911 EDPHRLAPEGLRGLAVSGLPPQ--KPSAPP 2938
+ P+G PPQ +PS PP
Sbjct: 398 Q------PQG------PPRPPQGGRPSRPP 415
Score = 56.6 bits (135), Expect = 7e-07
Identities = 79/288 (27%), Positives = 89/288 (30%), Gaps = 80/288 (27%)
Query: 2107 PPQPG--ALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP 2164
PPQ G G PPP G P P + + P G GP P
Sbjct: 205 PPQGGNKPQGPPPP--------GKPQGPPPQGDNKSQSARSPPGKPQGP----------P 246
Query: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGAS-SRPGAGQP 2223
PQ Q P P P P P P P P G P PP G S SR P
Sbjct: 247 PQGGNQPQGPPP---PPGKPQGP--PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPP 301
Query: 2224 GEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRK 2283
G+ PP P P KP+ P P GG K PPP G+ +
Sbjct: 302 GKPQGPPPQGGNQPQGPPPPPGKPQGP----------PPQGGNKPQ----GPPPPGKPQ- 346
Query: 2284 ALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSP 2343
GPP G S S+ ++P P Q PQ
Sbjct: 347 ----------------GPPPQGGSKSRSA---------RSP--------PGKPQGPPQQE 373
Query: 2344 GLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
G PQ PPP P P P P +PP RP PP
Sbjct: 374 --GNNPQGPPPPAGGNPQQPQAP----PAGQPQGPPRPPQGGRPSRPP 415
Score = 55.1 bits (131), Expect = 2e-06
Identities = 98/391 (25%), Positives = 126/391 (32%), Gaps = 63/391 (16%)
Query: 888 EPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP-------SLSPQLMPPDPLPPPLS 940
E S S + G P G PP + P SP G+P PQ PP P P
Sbjct: 26 EESPSLIAGNPQ----GAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 81
Query: 941 PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMI 1000
P P P G+ + P +GD SP + P P PPP+ P PP
Sbjct: 82 PPQGGNKPQGPPPPGKPQGP-PPQGDKS-RSPRSPP--GKPQGPPPQGGNQPQGPPPPPG 137
Query: 1001 LPPSP-----GSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPL 1055
P P P GP P + PPQ + S P P Q PP P
Sbjct: 138 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKP--QGPPPQGGNQPQGPP 195
Query: 1056 SPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDF 1115
P GK G + ++P+ P P P P GD + P
Sbjct: 196 PPPGKPQGPPPQGG---------NKPQGP--PPPGKPQGPPPQGDNKSQSARSPP----- 239
Query: 1116 SGLGEDTAPLDGIDAPGSQPEPGQ---TPGSLASELKGSPVLLDPEELAPVTPMEVYPE- 1171
G + P G G P PG+ P ++ +G P P P P+
Sbjct: 240 -GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP--------PPGKPQGPPPQG 290
Query: 1172 -CKQTAGQGSPCEEQEEP----RAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPL 1226
K + + P + Q P P P PP + N QG P
Sbjct: 291 GSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP----- 345
Query: 1227 LGSPDPEGGG-SLSMELGVSTDVSPARDEGS 1256
P P+GG S S P + EG+
Sbjct: 346 -QGPPPQGGSKSRSARSPPGKPQGPPQQEGN 375
Score = 53.1 bits (126), Expect = 7e-06
Identities = 101/387 (26%), Positives = 125/387 (32%), Gaps = 96/387 (24%)
Query: 4041 PSTHQGGPLAIGTTPESMATEPGEVK-PSLSGDSQLLLVQPQPQPQ---PSSLQLQPPLR 4096
P QG P G P+ PG+ + P G ++ P +PQ P + + P
Sbjct: 54 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 113
Query: 4097 LPGQQQ-------QQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMT 4149
PG+ Q Q G G G + P Q GD +
Sbjct: 114 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSS 173
Query: 4150 QNLLG-PQQPMLERPMQNNTGPQPPKP------GPVLQSG---QGLPGVGIM---PTVGQ 4196
++ G PQ P P Q PQ P P GP Q G QG P G P G
Sbjct: 174 RSPPGKPQGP----PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 229
Query: 4197 LRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGL 4256
++Q A++P + P Q Q Q PP Q P QG
Sbjct: 230 NKSQS----ARSPPGKPQGPPPQGGNQP--------------QGPPPPPGKPQGPPPQG- 270
Query: 4257 LGCQPQLGGFPGPQTGPLQELGAGPR--------PQGPPRL--------PAPPGALSTGP 4300
G +PQ PG GP + G+ R PQGPP P PPG P
Sbjct: 271 -GNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 329
Query: 4301 VLGPVHPT--PPPSSPQEP--------------------------KRPSQLPSPSSQLPT 4332
G P PPP PQ P P P P+ P
Sbjct: 330 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 389
Query: 4333 EAQLPPTHPGTPKPQGPTLEPPPGRVS 4359
+ Q PP +PQGP P GR S
Sbjct: 390 QPQAPP----AGQPQGPPRPPQGGRPS 412
Score = 47.4 bits (111), Expect = 4e-04
Identities = 54/170 (31%), Positives = 62/170 (36%), Gaps = 32/170 (18%)
Query: 4239 QTPPYQEPGTQTSPLQGLLGCQPQ-LGGFPGPQTGPLQELGAGP-------RPQGPP--- 4287
Q PP Q P QG G QPQ PG GP + G P +PQGPP
Sbjct: 48 QGPPSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 105
Query: 4288 ---RLP-APPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT 4343
R P +PPG P G P PP P +P Q P P + PP P
Sbjct: 106 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP----QGPPPQGGNKPQGPPPPGKPQG 161
Query: 4344 PKPQGP----TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389
P PQG + PPG+ Q G P PP + Q P
Sbjct: 162 PPPQGDNKSRSSRSPPGKPQGPPPQ-------GGNQPQGPPPPPGKPQGP 204
Score = 46.2 bits (108), Expect = 9e-04
Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 26/109 (23%)
Query: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRP-------- 4320
PQ P Q G +PQGPP +PPG P G P PP P +P+ P
Sbjct: 36 PQGAPPQ---GGNKPQGPP---SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 89
Query: 4321 --------SQLPSPSSQLPTEAQLPPTHPGTPKPQGPTL----EPPPGR 4357
Q P P + PP P P PQG PPPG+
Sbjct: 90 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 138
Score = 42.4 bits (98), Expect = 0.013
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 7/77 (9%)
Query: 4909 PPPEEPSPPP------SPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLA-SSPESARP 4961
PPP +P PP S A SP P P + P PP P +P + +P
Sbjct: 340 PPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP 399
Query: 4962 KPRARPPEEGEDSRPPR 4978
+ RPP+ G SRPP+
Sbjct: 400 QGPPRPPQGGRPSRPPQ 416
Score = 42.0 bits (97), Expect = 0.017
Identities = 78/310 (25%), Positives = 96/310 (30%), Gaps = 83/310 (26%)
Query: 4034 SSEATEGPSTHQGGPLAIGTTPESMATEPGEVK--PSLSGDSQLLLVQPQPQPQPSSLQL 4091
S + P QG P G P+ PG+ + P G+ +PQ P P Q
Sbjct: 170 SRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN------KPQGPPPPGKPQG 223
Query: 4092 QPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQN 4151
PP G S A S P P G+QP
Sbjct: 224 PPPQ------------------------GDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259
Query: 4152 LLGPQQPMLERPMQNNTGPQ-PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQ 4210
PQ P P Q PQ PP PG QG P G + +++P
Sbjct: 260 PGKPQGP----PPQGGNKPQGPPPPG----KPQGPPPQGGSKSRS----------SRSPP 301
Query: 4211 LRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQ 4270
+ P Q Q Q PP Q P QG G +PQ PG
Sbjct: 302 GKPQGPPPQGGNQP--------------QGPPPPPGKPQGPPPQG--GNKPQGPPPPGKP 345
Query: 4271 TGPLQELGAGPR--------PQGPPRL--------PAPPGALSTGPVLGPVHPTPPPSSP 4314
GP + G+ R PQGPP+ P P G P P P P
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 405
Query: 4315 QEPKRPSQLP 4324
+ RPS+ P
Sbjct: 406 PQGGRPSRPP 415
Score = 37.0 bits (84), Expect = 0.55
Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 9/69 (13%)
Query: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968
PPP +P PP P PP P +P PP + SP S KP+ PP
Sbjct: 73 PPPGKPQGPPPQGGNKPQGPPP------PGKPQGPPPQGDK---SRSPRSPPGKPQGPPP 123
Query: 4969 EEGEDSRPP 4977
+ G + P
Sbjct: 124 QGGNQPQGP 132
Score = 35.8 bits (81), Expect = 1.2
Identities = 23/74 (31%), Positives = 28/74 (37%), Gaps = 8/74 (10%)
Query: 4905 QLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
Q + PP +P PP P PP P +P PP P P KP+
Sbjct: 233 QSARSPPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPG---KPQ 284
Query: 4965 ARPPEEGEDSRPPR 4978
PP+ G SR R
Sbjct: 285 GPPPQGGSKSRSSR 298
Score = 35.8 bits (81), Expect = 1.2
Identities = 23/72 (31%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRAR 4966
S PP +P PP P PP P +P PP P P KP+
Sbjct: 297 SRSPPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPG---KPQGP 348
Query: 4967 PPEEGEDSRPPR 4978
PP+ G SR R
Sbjct: 349 PPQGGSKSRSAR 360
Score = 35.4 bits (80), Expect = 1.6
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 9/69 (13%)
Query: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPE 4969
PP +P PP P PP P +P PP P P KP+ PP
Sbjct: 53 PPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPG---KPQG-PPP 103
Query: 4970 EGEDSRPPR 4978
+G+ SR PR
Sbjct: 104 QGDKSRSPR 112
Score = 35.4 bits (80), Expect = 1.6
Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 13/79 (16%)
Query: 4911 PEEPSPPPSPLAP--------SPASPPTEPLVELP---TEPLAEPPVPSPLPLASSPESA 4959
P+ P PP P P SP SPP +P P +P PP P P P+
Sbjct: 89 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQGG 147
Query: 4960 RPKPRARPPEEGEDSRPPR 4978
KP+ PP PP+
Sbjct: 148 N-KPQGPPPPGKPQGPPPQ 165
Score = 35.0 bits (79), Expect = 2.1
Identities = 113/454 (24%), Positives = 143/454 (31%), Gaps = 68/454 (14%)
Query: 3731 AQKLQQQQQQQQQQQHLLG--QVAIQQ--QQQQGPGVQTNQALGPKPQGLMPPSSHQGLL 3786
AQ L + Q++ + G Q A Q + QGP + GP PQG P
Sbjct: 16 AQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQP------- 68
Query: 3787 VQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQG 3846
Q P PP PQG P Q Q P PQGP Q +SR SP QG
Sbjct: 69 --QGPPPPPGKPQG--PPPQGGNKPQGPPPPGKPQGPPPQ--GDKSRSPRSPPGKPQGPP 122
Query: 3847 LMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQL 3906
G Q Q G G P+ +P G + Q
Sbjct: 123 PQG-------GNQPQGPPPPPGKPQG------------PPPQGGNKPQGPPPPGKPQGPP 163
Query: 3907 QQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQF 3966
Q + + + Q Q Q Q + Q Q + Q + Q
Sbjct: 164 PQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 223
Query: 3967 QQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQ 4026
Q N+S++ SP + Q G P P P P G +
Sbjct: 224 PPPQGD------NKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ---GGNKP 274
Query: 4027 NTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVK--PSLSGDSQLLLVQPQ-PQ 4083
P P QG P G+ S + PG+ + P G+ QPQ P
Sbjct: 275 QGPPP---------PGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN------QPQGPP 319
Query: 4084 PQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGD 4143
P P Q PP G + Q G Q GS S S A S P P G+
Sbjct: 320 PPPGKPQGPPP---QGGNKPQGPPPPGKPQGPPPQGGSKSRS-ARSPPGKPQGPPQQEGN 375
Query: 4144 QPGSMTQNLLG-PQQPMLERPMQNNTGPQPPKPG 4176
P G PQQP Q P+PP+ G
Sbjct: 376 NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGG 409
Score = 34.7 bits (78), Expect = 2.7
Identities = 39/155 (25%), Positives = 51/155 (32%), Gaps = 33/155 (21%)
Query: 4827 GTEPKKGEAEGP----GGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQE 4882
G P G+ +GP G K +G GP P KS+ K +
Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP---------PQGDNKSRSSRSPPGKPQ 181
Query: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942
P P+ Q Q PPP +P PP P PP P +P
Sbjct: 182 GPPPQGGNQP------------QGPPPPPGKPQGPPPQGGNKPQGPPP------PGKPQG 223
Query: 4943 EPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
PP + S S KP+ PP+ G + P
Sbjct: 224 PPPQGD--NKSQSARSPPGKPQGPPPQGGNQPQGP 256
Score = 34.3 bits (77), Expect = 3.5
Identities = 40/157 (25%), Positives = 51/157 (32%), Gaps = 38/157 (24%)
Query: 4827 GTEPKKGEAEGP----GGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQE 4882
G P G+ +GP G K +G GP P KS+ K +
Sbjct: 70 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP----------PPQGDKSRSPRSPPGKPQ 119
Query: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942
P P+ Q Q PPP +P PP P PP P
Sbjct: 120 GPPPQGGNQP------------QGPPPPPGKPQGPPPQGGNKPQGPP----------PPG 157
Query: 4943 EPPVPSPLPLASSPESARP--KPRARPPEEGEDSRPP 4977
+P P P S S P KP+ PP+ G + P
Sbjct: 158 KPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP 194
Score = 33.9 bits (76), Expect = 4.6
Identities = 23/76 (30%), Positives = 30/76 (39%), Gaps = 8/76 (10%)
Query: 4909 PPPEEPSPPP------SPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPK 4962
PPP +P PP S + SP P P + +P PP P P P+ K
Sbjct: 154 PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQGGN-K 211
Query: 4963 PRARPPEEGEDSRPPR 4978
P+ PP PP+
Sbjct: 212 PQGPPPPGKPQGPPPQ 227
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 165 bits (417), Expect = 1e-39
Identities = 191/834 (22%), Positives = 306/834 (36%), Gaps = 107/834 (12%)
Query: 433 PLNEEMPLLPPPEESPLSPPPEESPTSP------PPEASRLSPPPEELPASPL-----PE 481
P+++ + PP +P SPPP + T P PP + +PPP P+ P+ P
Sbjct: 1391 PMDKCITTPSPPTTTP-SPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP 1449
Query: 482 ALHLSRPLEESPLSPPPEESPLSP-----PPESSPFSPLEESPLSPPEESPPSPALETPL 536
P + +PPP +P P PP ++P SP + +PP + PSP TP+
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTP-SPPTTTTTTPPPTTTPSPPTTTPI 1508
Query: 537 SPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP---- 592
+PP + L P S PP T+PPP + PP +P++PP + + P
Sbjct: 1509 TPPASTTTLPPTTTPS----PPTTTTTTPPPTTT--PSPPTTTPITPPTSTTTLPPTTTP 1562
Query: 593 -PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS 651
PP + PP +P SPP +P PP + +PPP +P PP + +PPP +
Sbjct: 1563 SPPPTTTTTPPPTTTP-SPPTTTTP--SPPTITTTTPPPTTTP--SPPTTTTTTPPPTTT 1617
Query: 652 RLSPLPVVSRLSPPPEESPLSP-----PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706
SP P + ++PP + L P PP + T+PPP +P P + T PP +
Sbjct: 1618 P-SP-PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT---TPSPPTTTTPSPPITTT 1672
Query: 707 ASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP-----RPEEPHLSPRPEEPHL 761
+PPP + SP+ P P + P +P P + P P
Sbjct: 1673 TTPPPTTT------PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPT 1726
Query: 762 SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE 821
+ P +P P + +P SP L+ P ++P T P + P
Sbjct: 1727 TMTTPSPTTTPSPPTTTMTTLPPTTTSSP------LTTTPLPPSITPPTFSPFSTTTPTT 1780
Query: 822 PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPR--------PEKPPEEPGQ 873
PC+ L S +P ++ L ++ P + P+ P + GQ
Sbjct: 1781 PCVPLCNWTGWL--DSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQ 1838
Query: 874 -----------CPAPEELPLFPPPGEPSLSPLLGEPALSEPGEP-PLSPLPEELPLSPSG 921
C ++ P P L+ + +P ++ E P P+
Sbjct: 1839 TVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTT 1898
Query: 922 EPSLSPQLMPPDPLP-----PPLSPI-ITAAAPPALSPLGELEYPFGAKGDSDPESPLAA 975
P + + P P P P +PI T P +P G + +P
Sbjct: 1899 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1958
Query: 976 PI-LETPISPPPEANCT-DPEPVPPMILPPSPGSPVGPASPILMEPLP-----PQCSPLL 1028
P +TP + P T P P P P+ +P+ + + P P P +P+
Sbjct: 1959 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 2017
Query: 1029 QHSLV-PQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE 1087
+ V P +P +P P++ + ++P G T V+ P
Sbjct: 2018 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT----PTPT 2073
Query: 1088 PSAT-SPLPSPMGDLSCPAPSPAPALDDFSGLG--EDTAPLDGIDAPGSQPEPGQTPGSL 1144
P+ T +P +P+ + P+P P T + P P TP +
Sbjct: 2074 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133
Query: 1145 ASELKGSPVLLDPE--ELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTP 1196
+ + +P + P+T G +P V PTP
Sbjct: 2134 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2187
Score = 84.0 bits (206), Expect = 4e-15
Identities = 111/464 (23%), Positives = 147/464 (31%), Gaps = 123/464 (26%)
Query: 2176 PFGLAPAY--------PLEPRFPT-APPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEF 2226
PFGL Y P++ T +PPT P P PT PP
Sbjct: 1375 PFGLCYDYKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPP---------------- 1418
Query: 2227 HTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPE----SPGVGGGKASEPLLSPPPFGESR 2282
TT P P +TP P P P P SP + P +P P
Sbjct: 1419 -TTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSP----- 1472
Query: 2283 KALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQS 2342
++PS PP SP + T TP P P + + P +
Sbjct: 1473 ----------PTTTPS--PPTT--TPSPPTTT------TTTPPPTTTPSPPTTTPITPPA 1512
Query: 2343 PGLGLRPQ---EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP-PPPESCCAL 2398
L P PP P P + P T P + L P P PPP +
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1572
Query: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLT-PRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP 2457
PP + PS P + P+ P +++ P T P P + P P T +P P + P P
Sbjct: 1573 PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT----TPSPPTTTPITP 1628
Query: 2458 QSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPN 2517
+ P P P P PP
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTT-----------------------------------TPP- 1652
Query: 2518 FVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQS 2577
P T TPSP T P PP+ PPP S P T P +
Sbjct: 1653 ----PTT-----TPSPPTTTTPS--------PPITTTTTPPPTTTPS--SPITTTPSPPT 1693
Query: 2578 TNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621
T T + P+ +P P + +T S +P PP+ + P+P
Sbjct: 1694 TTMTTPS----PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSP 1733
Score = 81.3 bits (199), Expect = 3e-14
Identities = 111/452 (24%), Positives = 146/452 (32%), Gaps = 82/452 (18%)
Query: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166
P P SPPP + T+ TTP+ +T+ PP + P P
Sbjct: 1399 PSPPTTTPSPPPTSTTTL--PPTTTPSPPTTTTT---TPPPTTTPSP------------- 1440
Query: 2167 VPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEF 2226
P + P P+ P+ T PPT P P PT P+ P ++ P P
Sbjct: 1441 -PITTTTTPPPTTTPSPPISTT-TTPPPTTTPSP-PTTTPSPP-----TTTPSP--PTTT 1490
Query: 2227 HTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALE 2286
TTPP T P T P P + SP P +P P +
Sbjct: 1491 TTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1550
Query: 2287 VKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLG 2346
L ++ PP P++ +P P + P +
Sbjct: 1551 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT--- 1607
Query: 2347 LRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP-PPPESCCALPPRSLPS 2405
PPP PSPP+ I P S T L P P PPP + PP + PS
Sbjct: 1608 -TTTTPPPTTT--PSPPTTTPITPPTSTTT------LPPTTTPSPPPTTTTTPPPTTTPS 1658
Query: 2406 DPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAP 2465
P + P SP +++ P T P S PSP T +P P + P S P
Sbjct: 1659 PPTTTTP-SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS------PITT 1711
Query: 2466 LHKP---PRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP 2522
P P PP S P P+ P + + PP SP
Sbjct: 1712 TTTPSSTTTPSPPPTTMTTPS-----------PTTTPSPPTTTM-----TTLPPTTTSSP 1755
Query: 2523 GTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQP 2554
T TP P PS+ PP P
Sbjct: 1756 LT----TTPLP-----------PSITPPTFSP 1772
Score = 80.5 bits (197), Expect = 4e-14
Identities = 100/410 (24%), Positives = 137/410 (33%), Gaps = 75/410 (18%)
Query: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPG 2224
P P PS P P P+ P T P PT P+ PP+ ++ P
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTT--PSPPTTTTTTPPPTTTPS-PPITTTTTPPP----- 1450
Query: 2225 EFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKA 2284
TT P P +TP P P P+ P P + +PPP
Sbjct: 1451 ---TTTPSPPISTTTTPPPTTTPSPPT----TTPSPPTTTPSPPTTTTTTPPP------- 1496
Query: 2285 LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELK--------TPDVFKAPLTPRAS 2336
++PS PP + P+S T L TP P P +
Sbjct: 1497 ---------TTTPS--PPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1545
Query: 2337 QVEPQSPGLGLRPQ---EPPPAQALAPSP---PSHPDIFRPGSYTDPYAQPPLTPRPQPP 2390
+ P + L P PPP P P PS P P T PP T P PP
Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPP 1605
Query: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPY 2450
+ PP + PS P + P +P + +++ P T PSP +P P
Sbjct: 1606 TTTTTTP-PPTTTPSPP-TTTPITPPTSTTTLPPTTT---------PSPPPTTTTTPPP- 1653
Query: 2451 SRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKV 2510
+ PS P + P P+ PP + + T P+ P +
Sbjct: 1654 TTTPSPPTTTTPSPPI--TTTTTPPPTTTPSSPITTT-----------PSPPTTTMTTPS 1700
Query: 2511 PSGQPPNFVRSPGTGAFVGTPS--PMRFTFPQAVGEPSLKPPVPQPGLPP 2558
P+ P + + + T + TPS P T P PS P LPP
Sbjct: 1701 PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS-PPTTTMTTLPP 1749
Score = 71.6 bits (174), Expect = 2e-11
Identities = 92/363 (25%), Positives = 124/363 (34%), Gaps = 55/363 (15%)
Query: 2115 SPPPAAAPTIFIGSPTTPAGLSTSADGFLKP-PAGSVPGPDS-----PGELFLKLPPQVP 2168
+PPP P+ I + TTP +T + P P + P P + P PP
Sbjct: 1447 TPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1506
Query: 2169 AQVPSQDPFGLAPAYPLEPRFPTA---PPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGE 2225
P L P P T PPT P P PT P PP + P
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSP-PTTTPITPPTSTTTLPP------- 1558
Query: 2226 FHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKAL 2285
TT P P +TP P P P+ P P + +PPP
Sbjct: 1559 --TTTPSPPPTTTTTPPPTTTPSPPTT---TTPSPPTI-------TTTTPPPTTTPSPPT 1606
Query: 2286 EVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ---- 2341
++PS PP + P+S T L +P P + P
Sbjct: 1607 TTTTTPPPTTTPS--PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1664
Query: 2342 -SPGLGLRPQEPP---PAQALA--PSPPSHPDIFRPGSYTDPYAQPPLTPRPQP-----P 2390
SP + PP P+ + PSPP+ + P T P + T P P
Sbjct: 1665 PSPPITTTTTPPPTTTPSSPITTTPSPPT-TTMTTPSPTTTPSSPITTTTTPSSTTTPSP 1723
Query: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPY 2450
PP + P + PS P + + P + +SS PLT PL P +TP SP
Sbjct: 1724 PPTTMTTPSPTTTPSPPTTTMTTLPPTTTSS--PLTTTPL------PPSITPPTFSPFST 1775
Query: 2451 SRP 2453
+ P
Sbjct: 1776 TTP 1778
Score = 67.4 bits (163), Expect = 4e-10
Identities = 80/356 (22%), Positives = 108/356 (30%), Gaps = 31/356 (8%)
Query: 859 PLSPRPEKPPEE-----PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPE 913
P + P PP P P+P PP + SP + P P P+
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIST 1460
Query: 914 ELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP-PALSPLGELEYPFGAKGDSDPESP 972
P+ PS P P P P P T P P +P P + P S
Sbjct: 1461 TTTPPPTTTPS-PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI-----TPPAST 1514
Query: 973 LAAPILETPISPPPEANCTDP---EPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQ 1029
P TP SPP T P P PP P +P + P PP +
Sbjct: 1515 TTLPPTTTP-SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1573
Query: 1030 HSLVPQNSPPSQCSPPALPLSVPSPLS----PIGKVVGVSDEAELHEMETEKVSEPECPA 1085
+ P + SPP + + P P + P T ++ P
Sbjct: 1574 PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1633
Query: 1086 LEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLA 1145
P T+P P P + P P+ P+ T P I + P P TP S
Sbjct: 1634 TLPPTTTPSPPPT-TTTTPPPTTTPSPP------TTTTPSPPITTT-TTPPPTTTPSSPI 1685
Query: 1146 SELKGSP---VLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPT 1198
+ P + P +P+ T P P P+PPT
Sbjct: 1686 TTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPT 1741
Score = 64.3 bits (155), Expect = 3e-09
Identities = 84/356 (23%), Positives = 116/356 (32%), Gaps = 52/356 (14%)
Query: 2097 TDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDS- 2155
T P + P P SPP P+ +P+ P +T+ PP + P P +
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPP-TTTPSPPTTTPSPPTTTTTT------PPPTTTPSPPTT 1505
Query: 2156 ----PGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPS----PTGAPA 2207
P LPP P+ P P PT P PP + PT P+
Sbjct: 1506 TPITPPASTTTLPPTTTPSPPTTTT--TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1563
Query: 2208 QPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGK 2267
PP ++ P P TT P P +TP P P P+ P
Sbjct: 1564 PPPTT-TTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP--------- 1613
Query: 2268 ASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVF 2327
P +P P + L ++ PP P++ +P +
Sbjct: 1614 ---PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPIT 1670
Query: 2328 KAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPD-----IFRPGSYTDPYAQPP 2382
P + P SP + P PP PSP + P P S T P + PP
Sbjct: 1671 TTTTPPPTTT--PSSP-ITTTPS-PPTTTMTTPSPTTTPSSPITTTTTPSSTTTP-SPPP 1725
Query: 2383 LT-----PRPQPPPPESCCALPPRSLPSDPFSRVPASPQ------SQSSSQSPLTP 2427
T P P PP + P + S P + P P S S+ +P TP
Sbjct: 1726 TTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781
Score = 62.4 bits (150), Expect = 1e-08
Identities = 119/660 (18%), Positives = 222/660 (33%), Gaps = 99/660 (15%)
Query: 444 PEESPLSPPPEESPTSPPP--EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEES 501
P +P++ +PT P + +P +P P P +P++ +
Sbjct: 3667 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVT 3725
Query: 502 PLSPP-----PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPL-SPPFEESPLS 555
P P P ++P + +P +P TP++ +P +P ++P +
Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTT 3784
Query: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615
P T P + P +P++ +P +P P + ++P + P +
Sbjct: 3785 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGT-------QTPTTTPITTT 3836
Query: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP--EVSRLSPLPVVSRLSPPPEESPLSP 673
P + P +P++ +P P + +P+ + ++P P +P
Sbjct: 3837 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TP 3891
Query: 674 PPEESPTSPP-PEASRLSPPP-----EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP 727
++PT+ P + ++P P + T+P + +P P + P
Sbjct: 3892 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3951
Query: 728 LPEEPQLCPR-SEGPHLSPRPEEPHLSPRP-----EEPHLSPQAEEPHLSPQPEEPCLCA 781
P P ++ P +P ++P P + P +P ++P P
Sbjct: 3952 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP----T 4007
Query: 782 VPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPC 841
+ P +P ++P P T+ P +P+ ++P P + + P
Sbjct: 4008 GTQTPTTTPITTTTTVTPTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4063
Query: 842 -----LSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFP---------PPG 887
++P P + P + P P P P+ P G
Sbjct: 4064 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4123
Query: 888 E--PSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITA 945
P+ +P+ ++ P + P P++ + +++P P P +PI T
Sbjct: 4124 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTT 4181
Query: 946 AA-PPALSPLGELEYPFGAKGDSDPESPLAAPILE-TPISPPPEANCTDPE--------- 994
P +P G P P API E T +PPPE++
Sbjct: 4182 TTVTPTPTPTGTQTGP--------PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE 4233
Query: 995 ------PVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALP 1048
+PP I S P P +P H+L P P + SPP P
Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSG---------GHTLSP--PPSTTTSPPGTP 4282
Score = 59.7 bits (143), Expect = 8e-08
Identities = 72/325 (22%), Positives = 115/325 (35%), Gaps = 67/325 (20%)
Query: 433 PLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES 492
P+ + P P +P ++PT+ P + P + P ++ +
Sbjct: 4108 PITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4162
Query: 493 PLSPP-----PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALE-TPLSPPPEASPLS 546
P P P +P++ +P + PP + +P E T +PPPE+S +
Sbjct: 4163 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESS--T 4220
Query: 547 PPFEESPLSPPPEE--LPTSPPPEASRLSPPPEESPMSP----------PPEESPMSPPP 594
P S SP E L ++ PP S P +P +P PP + SPP
Sbjct: 4221 PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG 4280
Query: 595 EASRLFPPFEESPLSP-----------PPEESPLSPPP--EASRLSPPPEDSPMSPPPEE 641
+R S +P P +PLS P + L P P + +
Sbjct: 4281 TPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLND 4340
Query: 642 SPMSPPPEV----------------------------SRLSPLPVVSRLSPPPEESPLSP 673
+ +P EV S SP P S+ +P P + P S
Sbjct: 4341 TYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSK-PSST 4399
Query: 674 PPEESPTSPPPEASRLSPPPEDSPT 698
P + +P + PPE PP +++ T
Sbjct: 4400 PSKPTPGTKPPECPDFDPPRQENET 4424
Score = 57.4 bits (137), Expect = 4e-07
Identities = 74/305 (24%), Positives = 117/305 (38%), Gaps = 27/305 (8%)
Query: 433 PLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES 492
P+ + P P +P ++PT+ P + P + P ++ +
Sbjct: 4131 PITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4185
Query: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA----SPLSPP 548
P +P P + PP +S E + +PP ES + SP E+ S L P
Sbjct: 4186 P-TPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPA 4244
Query: 549 FEESPLSPPPEELPTSPPPEAS--RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEES 606
E + +PP PT+P + LSPPP + SPP + + +S P ++
Sbjct: 4245 IEMTSTAPP--STPTAPTTTSGGHTLSPPPSTTT-SPPGTPTRGTTTGSSSAPTPSTVQT 4301
Query: 607 PLSPP--PEESPLSPPP--EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP----V 658
+ P +PLS P + L P P + ++ +P EV + V
Sbjct: 4302 TTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFV 4361
Query: 659 VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718
LS E S P SPT P + S P P+S P + +P + PPE
Sbjct: 4362 NCSLSCTLEFYNWSCPSTPSPTPTPSK----STPTPSKPSSTPSKPTPGTKPPECPDFDP 4417
Query: 719 PLEES 723
P +E+
Sbjct: 4418 PRQEN 4422
Score = 52.0 bits (123), Expect = 2e-05
Identities = 99/565 (17%), Positives = 184/565 (32%), Gaps = 52/565 (9%)
Query: 665 PPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA---SPPPEDSLMSLPLE 721
PP +P++ +PT P + P + T+ P +P +P + +
Sbjct: 1895 PPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1954
Query: 722 ESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCA 781
+P + P P + ++P P + P +P ++P P
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTVTPTPTP----T 2006
Query: 782 VPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQP-----EESHLSPQ 836
+ P +P ++P P T+ P +P+ ++P P + +P
Sbjct: 2007 GTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2062
Query: 837 SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPL------FPPP---- 886
+ ++P P + P + P P P P+ P P
Sbjct: 2063 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2122
Query: 887 -GEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPI-IT 944
P+ +P+ ++ P + P P++ + +++P P P +PI T
Sbjct: 2123 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTT 2180
Query: 945 AAAPPALSPLGELEYPFGAKGDSDPESPLAAPI-LETPISPPPEANCT-DPEPVPPMILP 1002
P +P G + +P P +TP + P T P P P
Sbjct: 2181 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2240
Query: 1003 PSPGSPVGPASPILMEPLP-----PQCSPLLQHSLV-PQNSPPSQCSPPALPLSVPSPLS 1056
P+ +P+ + + P P P +P+ + V P +P +P P++ + ++
Sbjct: 2241 PTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2299
Query: 1057 PIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT-SPLPSPMGDLSCPAPSPAPALDDF 1115
P G T V+ P P+ T +P +P+ + P+P P
Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVT----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2355
Query: 1116 SGLG--EDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPE--ELAPVTPMEVYPE 1171
T + P P TP + + + +P + P+T
Sbjct: 2356 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2415
Query: 1172 CKQTAGQGSPCEEQEEPRAPVAPTP 1196
G +P V PTP
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPTP 2440
Score = 47.0 bits (110), Expect = 5e-04
Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 6/79 (7%)
Query: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLA-PSPASPPTEPLVELPTEPLAEP 4944
P PPT T S + PP PSPPP+ P P + P+ P P+ P+
Sbjct: 1618 PSPPTTTPITPPTSTTTL-----PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTT 1672
Query: 4945 PVPSPLPLASSPESARPKP 4963
P P SSP + P P
Sbjct: 1673 TTPPPTTTPSSPITTTPSP 1691
Score = 46.2 bits (108), Expect = 9e-04
Identities = 111/544 (20%), Positives = 163/544 (29%), Gaps = 82/544 (15%)
Query: 2106 IPPQPGALGSPPPAAAP---TIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLK 2162
+ P P G+ P P T + TP G T + P P G
Sbjct: 3839 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT---- 3894
Query: 2163 LPPQVPAQVPSQDPFGLAPA-YPLEPRFPTAPP-----TYPPYPSPTGA--PAQPPMLGA 2214
Q P P + P P + PT P T P P+PTG P P+
Sbjct: 3895 ---QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3951
Query: 2215 SSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLS 2274
++ P T TP P T + P P+ P + + P +
Sbjct: 3952 TTVTPTPTP-----TGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPT 4005
Query: 2275 PPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPS---SGTHLGGLELKTPDVFKAPL 2331
P G +P+ P +P+ +GT T P
Sbjct: 4006 PT----------------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4049
Query: 2332 -TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP 2390
TP +Q +P P P +P + P + P P T P
Sbjct: 4050 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP--ITTTTTVTPTPTPTGTQTPTTT 4107
Query: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ-SPDP 2449
P + + P P+ ++ P + +++ TP P + +P+T +P P
Sbjct: 4108 PITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4165
Query: 2450 YSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAK 2509
P + P P P + G HTS P EL
Sbjct: 4166 TPTGTQTPTTTPITTTTTVTPTPTP--TGTQTGPPTHTS-----------TAPIAELTTS 4212
Query: 2510 VPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPV-----------------P 2552
P + S T + + + + T P A+ S PP P
Sbjct: 4213 NPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP 4272
Query: 2553 QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRP 2612
PP G + ST T T + P+ +PL S+ S + GL P P
Sbjct: 4273 STTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPL--STPSIIRTTGLRPY-P 4329
Query: 2613 PSVL 2616
SVL
Sbjct: 4330 SSVL 4333
Score = 43.5 bits (101), Expect = 0.006
Identities = 38/130 (29%), Positives = 48/130 (36%), Gaps = 19/130 (14%)
Query: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP 4326
P P T P + P P P+PP + +T TPPP++ P P+ PSP
Sbjct: 1432 PPPTTTPSPPITTTTTPP-PTTTPSPPISTTT---------TPPPTTTPSP--PTTTPSP 1479
Query: 4327 SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAET 4386
PT PPT T P PT P P +P + T P PP T
Sbjct: 1480 ----PTTTPSPPTTTTTTPP--PTTTPSPPTTTPITPPASTTTLPPTTTP-SPPTTTTTT 1532
Query: 4387 QKPEQSSLVP 4396
P + P
Sbjct: 1533 PPPTTTPSPP 1542
Score = 43.5 bits (101), Expect = 0.006
Identities = 40/147 (27%), Positives = 48/147 (32%), Gaps = 24/147 (16%)
Query: 4850 PDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAP 4909
P T P LP T S + + P PPT T S + + P
Sbjct: 1542 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT----TTTPSPPTITTTTPP 1597
Query: 4910 PPEEPSPP------------PSPLAPSPASPPTEPLVELPTEPLAEPP----VPSPLPLA 4953
P PSPP PSP +P +PPT PT + PP P P
Sbjct: 1598 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1657
Query: 4954 SSPESARPKP----RARPPEEGEDSRP 4976
S P + P P PP S P
Sbjct: 1658 SPPTTTTPSPPITTTTTPPPTTTPSSP 1684
Score = 42.7 bits (99), Expect = 0.010
Identities = 54/258 (20%), Positives = 77/258 (29%), Gaps = 29/258 (11%)
Query: 960 PFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP------------SPGS 1007
PFG D P+ + +P P P P LPP +P
Sbjct: 1375 PFGLCYDYKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPP 1434
Query: 1008 PVGPASPILMEPLPPQC---SPLLQHSLV--PQNSPPSQCSPPALPLSVPSPLSPIGKVV 1062
P+ PI PP SP + + P +P + P+ P + PSP P
Sbjct: 1435 TTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSP--PTTTTT 1492
Query: 1063 GVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGL--GE 1120
T ++ P P T+P P P + P P+ P+ + +
Sbjct: 1493 TPPPTTTPSPPTTTPITPPASTTTLPPTTTPSP-PTTTTTTPPPTTTPSPPTTTPITPPT 1551
Query: 1121 DTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGS 1180
T L P P TP + + P + TP T
Sbjct: 1552 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTP-------PPTTTPSP 1604
Query: 1181 PCEEQEEPRAPVAPTPPT 1198
P P P+PPT
Sbjct: 1605 PTTTTTTPPPTTTPSPPT 1622
Score = 42.7 bits (99), Expect = 0.010
Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 7/101 (6%)
Query: 4283 PQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL---PTEAQLPPT 4339
P P P+PP + P TPPP++ P + + P+S PT PPT
Sbjct: 1470 PSPPTTTPSPPTTTPSPPT--TTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPT 1527
Query: 4340 HPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
T P PT P P +P + T P PP
Sbjct: 1528 TTTTTPP--PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566
Score = 40.8 bits (94), Expect = 0.038
Identities = 32/122 (26%), Positives = 43/122 (35%), Gaps = 9/122 (7%)
Query: 4283 PQGPPRLPAPPGALSTG--PVLGPVHPT------PPPSSPQEPKRPSQLPSPSSQLPTEA 4334
P P P+PP +T P P PT PP ++P P + P P++
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 4335 QLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSL 4394
T P T P PT P P +P+ T P PP T ++L
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP-SPPTTTPITPPASTTTL 1517
Query: 4395 VP 4396
P
Sbjct: 1518 PP 1519
Score = 40.0 bits (92), Expect = 0.064
Identities = 46/176 (26%), Positives = 60/176 (34%), Gaps = 25/176 (14%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTG 4299
T P T T+P P P P T P P P P+PP +T
Sbjct: 1452 TTPSPPISTTTTPPPTTTPSPPTTTPSP-PTTTPSPPTTTTTTPP-PTTTPSPP---TTT 1506
Query: 4300 PVLGPVHPT--PPPSSPQEPKR------PSQLPSPSSQLP-----TEAQLPPTHPGTPKP 4346
P+ P T PP ++P P P+ PSP + P + LPPT +P P
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566
Query: 4347 QGPTLEPP------PGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVP 4396
T PP P +P+ + T P PP T P + P
Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP-SPPTTTTTTPPPTTTPSPP 1621
Score = 39.7 bits (91), Expect = 0.084
Identities = 35/151 (23%), Positives = 46/151 (30%), Gaps = 23/151 (15%)
Query: 4850 PDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYT--YNVSNLDVRQLS 4907
P T P LP T S + + P PPT T + + L
Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1562
Query: 4908 APPPEEPSPPPSPLAPSP---------------------ASPPTEPLVELPTEPLAEPPV 4946
+PPP + PP PSP SPPT P PP
Sbjct: 1563 SPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPT 1622
Query: 4947 PSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
+P+ +S + P PP + PP
Sbjct: 1623 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1653
Score = 39.7 bits (91), Expect = 0.084
Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 14/98 (14%)
Query: 4267 PGPQTGPLQELGAGPRP-------QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKR 4319
P P T P + P P P P+ P +T P P+PPP++ P
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTP-SSTTTPSPPPTTMTTPS- 1732
Query: 4320 PSQLPSPSSQLPTEAQLPPT---HPGTPKPQGPTLEPP 4354
P+ PSP + T LPPT P T P P++ PP
Sbjct: 1733 PTTTPSPPT--TTMTTLPPTTTSSPLTTTPLPPSITPP 1768
Score = 39.3 bits (90), Expect = 0.11
Identities = 40/141 (28%), Positives = 51/141 (36%), Gaps = 23/141 (16%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQG-------PPRLPAP 4292
TPP T T P P P P T P P P P P+P
Sbjct: 1548 TPP---TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSP 1604
Query: 4293 PGALSTGPVLGPVHPTPPPSSPQEPKR------PSQLPSP-----SSQLPTEAQLPPTHP 4341
P +T P P+PP ++P P P+ PSP ++ PT PPT
Sbjct: 1605 PTTTTTTPP-PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1663
Query: 4342 GTPKPQGPTLEPPPGRVSPAA 4362
TP P T PP +P++
Sbjct: 1664 -TPSPPITTTTTPPPTTTPSS 1683
Score = 39.3 bits (90), Expect = 0.11
Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 9/64 (14%)
Query: 4909 PPPEEPSPP----PSP-----LAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESA 4959
PP PSPP PSP P P + P+ P+ P+ P PSP SSP +
Sbjct: 1652 PPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITT 1711
Query: 4960 RPKP 4963
P
Sbjct: 1712 TTTP 1715
Score = 38.9 bits (89), Expect = 0.14
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 7/95 (7%)
Query: 4286 PPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPK 4345
P P+PP +T P P TP P + P P+ + ++ PT PPT T
Sbjct: 1558 PTTTPSPPPTTTTTP---PPTTTPSPPTTTTPSPPTI--TTTTPPPTTTPSPPTTTTTTP 1612
Query: 4346 PQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
P PT P P +P + T P PP
Sbjct: 1613 P--PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1645
Score = 38.5 bits (88), Expect = 0.19
Identities = 31/134 (23%), Positives = 44/134 (32%), Gaps = 6/134 (4%)
Query: 4850 PDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAP 4909
P T P LP T S + + P PP + T + +S
Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTT 1461
Query: 4910 PPEEPSPPPSPLAPSPA------SPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
P+ PSP +P+ SPPT P PP +P+ +S + P
Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTT 1521
Query: 4964 RARPPEEGEDSRPP 4977
PP + PP
Sbjct: 1522 TPSPPTTTTTTPPP 1535
Score = 38.5 bits (88), Expect = 0.19
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 4886 PEPPTQH----SYTYNVSNLDVRQLSAPPPEEPSPPPSPLA-PSPA---SPPTEPLVELP 4937
P PPT S T S+ + PSPPP+ + PSP SPPT + LP
Sbjct: 1689 PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLP 1748
Query: 4938 TEPLAEPPVPSPLPLASSPESARPKPRARP 4967
+ P +PLP + +P + P P
Sbjct: 1749 PTTTSSPLTTTPLPPSITPPTFSPFSTTTP 1778
Score = 38.1 bits (87), Expect = 0.24
Identities = 25/90 (27%), Positives = 34/90 (37%), Gaps = 4/90 (4%)
Query: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEP-- 4940
+P+P T T S + PP PSPP + PAS T P P+ P
Sbjct: 1469 TPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTT 1528
Query: 4941 --LAEPPVPSPLPLASSPESARPKPRARPP 4968
PP +P P ++P + PP
Sbjct: 1529 TTTTPPPTTTPSPPTTTPITPPTSTTTLPP 1558
Score = 37.7 bits (86), Expect = 0.32
Identities = 69/381 (18%), Positives = 107/381 (28%), Gaps = 51/381 (13%)
Query: 4601 PTGPDYYSQLLTKNNLSNPPT-----PPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDA 4655
P+ P + L +PPT PP + P+PP + TPS +
Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP 1465
Query: 4656 ASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESIL 4715
+ S + + P+PP T + + I P +S ++
Sbjct: 1466 PTTTPSPPTTTPSPPTTT-------PSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518
Query: 4716 GEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWE 4775
P P + P P + P+ P T P P TT
Sbjct: 1519 PTTTPSPPTTTT-------TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1571
Query: 4776 KGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEA 4835
+ S T + + ++ P P T P
Sbjct: 1572 PPPTTTPSPPTTTTPSPP--------------TITTTTPPPTTTPSPPTTTTTTPPPTTT 1617
Query: 4836 EGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYT 4895
P P T P LP T S + + P PPT
Sbjct: 1618 PSP-----------PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTT---- 1662
Query: 4896 YNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASS 4955
+ + + PPP + P SP+ +P+ P T PT + P + P +++
Sbjct: 1663 -TTPSPPITTTTTPPPT--TTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTT 1719
Query: 4956 PESARPKPRARPPEEGEDSRP 4976
S P P S P
Sbjct: 1720 TPSPPPTTMTTPSPTTTPSPP 1740
Score = 37.4 bits (85), Expect = 0.42
Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 14/122 (11%)
Query: 4286 PPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKR------PSQLPSP-----SSQLPTEA 4334
P P+PP +T P P+PP ++P P P+ PSP ++ PT
Sbjct: 1519 PTTTPSPPTTTTTTPP-PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577
Query: 4335 QLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSL 4394
PPT TP P T PP +P+ T P PP T ++L
Sbjct: 1578 PSPPTTT-TPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTP-SPPTTTPITPPTSTTTL 1635
Query: 4395 VP 4396
P
Sbjct: 1636 PP 1637
Score = 37.0 bits (84), Expect = 0.55
Identities = 24/98 (24%), Positives = 36/98 (36%), Gaps = 3/98 (3%)
Query: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSP--ASPPTEPLVELPTEP 4940
+P+P T + + L +PP + PP PSP + T P P+ P
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457
Query: 4941 LAEPPVPSPLPLASSPESARPKPRARP-PEEGEDSRPP 4977
++ P P S P + P P P + PP
Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP 1495
Score = 35.0 bits (79), Expect = 2.1
Identities = 24/99 (24%), Positives = 36/99 (36%), Gaps = 4/99 (4%)
Query: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEP-SPPPSPLAPSPASPPTEPLVELPTEP- 4940
+P+P T T + +PP P +PP S P + P+ P T P
Sbjct: 1476 TPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPP 1535
Query: 4941 --LAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
PP +P+ +S + P PP + PP
Sbjct: 1536 TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1574
Score = 35.0 bits (79), Expect = 2.1
Identities = 31/117 (26%), Positives = 38/117 (32%), Gaps = 5/117 (4%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTG 4299
TPP T T P P P P T P P P PP +
Sbjct: 1627 TPP---TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSS 1683
Query: 4300 PV-LGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPP 4355
P+ P PT ++P PS P ++ P+ P P T PT P P
Sbjct: 1684 PITTTPSPPTTTMTTPSPTTTPSS-PITTTTTPSSTTTPSPPPTTMTTPSPTTTPSP 1739
Score = 35.0 bits (79), Expect = 2.1
Identities = 67/325 (20%), Positives = 97/325 (29%), Gaps = 64/325 (19%)
Query: 4028 TVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPS 4087
TV P + T+ P+T P+ TT T G P+ + + V P P P +
Sbjct: 4045 TVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4101
Query: 4088 SLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQP-G 4146
Q P P V+ T G ++ + + +V+ P G
Sbjct: 4102 ----QTPTTTPITTTTTVTPTPTPTG-----------TQTPTTTPITTTTTVTPTPTPTG 4146
Query: 4147 SMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLP-----GVGIMPTVGQLRAQL 4201
+ T P TG Q P P+ + P G P A +
Sbjct: 4147 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPI 4206
Query: 4202 QGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQP 4261
+ NP +PQ + + L +S + T P T T+P
Sbjct: 4207 AELTTSNPPPESSTPQTSRSTSS-----PLTESTTLLSTLPPAIEMTSTAP--------- 4252
Query: 4262 QLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPS 4321
P P P S G L P P+ S P P R +
Sbjct: 4253 -------------------------PSTPTAPTTTSGGHTLSPP-PSTTTSPPGTPTRGT 4286
Query: 4322 QLPSPSSQLPTEAQLPPTHPGTPKP 4346
S S+ P+ Q T TP P
Sbjct: 4287 TTGSSSAPTPSTVQTTTTSAWTPTP 4311
Score = 34.3 bits (77), Expect = 3.5
Identities = 39/134 (29%), Positives = 48/134 (35%), Gaps = 18/134 (13%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQ-----PQLGGFPGPQTGPLQELGA-GPRPQGPPRLPAPP 4293
TP GTQT + P G P T P+ P P PP
Sbjct: 4139 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPP 4198
Query: 4294 GALSTGPVLGPVHPTPPP--SSPQEPKRPSQLPSPS----SQLPTEAQL----PPTHPGT 4343
ST P+ PPP S+PQ + S + S S LP ++ PP+ P
Sbjct: 4199 THTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA 4258
Query: 4344 PKPQ--GPTLEPPP 4355
P G TL PPP
Sbjct: 4259 PTTTSGGHTLSPPP 4272
Score = 33.1 bits (74), Expect = 7.9
Identities = 41/164 (25%), Positives = 52/164 (31%), Gaps = 15/164 (9%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTG 4299
TPP P T SP P P T P+ P P+PP +T
Sbjct: 1595 TPP---PTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-PTSTTTLPPTTTPSPPPTTTTT 1650
Query: 4300 PVLGPVHPTPPPSSPQEPKRPSQLP----SPSSQLPTEAQLPPTHPGTPKPQGPTLEP-- 4353
P P ++P P + P +PSS + T P T TP P P
Sbjct: 1651 PPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710
Query: 4354 ----PPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSS 4393
P +P+ T S P PP T P +S
Sbjct: 1711 TTTTPSSTTTPSPPPTTMTTPSPTTTP-SPPTTTMTTLPPTTTS 1753
Score = 33.1 bits (74), Expect = 7.9
Identities = 28/103 (27%), Positives = 37/103 (35%), Gaps = 13/103 (12%)
Query: 4883 SPAPEP------PTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVEL 4936
+P P P P H+ T ++ L S PPPE +P S SP + T L L
Sbjct: 4185 TPTPTPTGTQTGPPTHTSTAPIAELTT---SNPPPESSTPQTSRSTSSPLTESTTLLSTL 4241
Query: 4937 P----TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSR 4975
P A P P+ S + P P G +R
Sbjct: 4242 PPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR 4284
>gi|61966919 hypothetical protein LOC442444 [Homo sapiens]
Length = 1035
Score = 162 bits (409), Expect = 1e-38
Identities = 206/702 (29%), Positives = 274/702 (39%), Gaps = 146/702 (20%)
Query: 391 ACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLS 450
+C+GQ K T+ +P EPG C + P+ P + LPP E P +
Sbjct: 164 SCEGQEK----TTDEPTEPGKYPCG---------EFSPR---PPETRVSCLPP--EPPKT 205
Query: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE--SPLSPPPE 508
P P P S L P P + S +LHL PPE S L P P
Sbjct: 206 PVSSLRPEPPETGVSHLRPQPPKTQVS----SLHLE----------PPETGVSHLRPEPP 251
Query: 509 SSPFSPLEESPLSPPEESPPSPALETP------LSPPPEASPLSPPFEESPLSPPPEELP 562
+ S L L PPE LE P L P P + +S E P + P+
Sbjct: 252 KTQVSSLH---LEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCL 308
Query: 563 TSPPPEASRLSPPPEESPMS---PPPEESPMS----PPPE--ASRLFPPFEESPLSP--- 610
P S L P P E+ +S P P ++ +S PPE S L P E+ +SP
Sbjct: 309 EPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQ 368
Query: 611 -PPEE--SPLSPPPEASRLSP-PPED-----SPMSPPPEESPM----SPPPEV------- 650
PPE S L P P +R+ P PE SP+ P P ++ + S PP++
Sbjct: 369 LPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCL 428
Query: 651 -------SRLSPLPV---VSRLSPPPEESPLS----PPPEES-----PTSPPPEASRLSP 691
S L P P VS L P P ++ +S PPE P P + S L P
Sbjct: 429 EPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRP 488
Query: 692 PPEDS------PTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP 745
P D+ P P S P P ++ +S E P + + Q P S HL P
Sbjct: 489 EPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRP 548
Query: 746 RPEE---PHLSPRPEEPHLSPQAEEP------HLSPQPEEPCLCAVPEEPHLSPQAEGPH 796
P E HL P P + + EP HL P+P + + ++P EP P+ H
Sbjct: 549 EPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEP---PETGVSH 605
Query: 797 LSPQPEELHLSPQTEEPHLSPVPEEPCLS---PQPEESHLSPQSEEPCLSPRPEESHLSP 853
L P+P P+T HL P P E +S P+P ++ + EP P SHL P
Sbjct: 606 LCPEP------PETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEP---PNTGVSHLCP 656
Query: 854 ELEKPPLSPRPEKPPEE--PGQCPAPEEL---PLFPPPGEPSLSPLLGEP----ALSEPG 904
E K +S P +PPE CP P E L P P E +S L EP S
Sbjct: 657 EPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHA 716
Query: 905 EPPLSPLPEELPLSP-SGEPSLSPQLMPPDP-----LPPPLSPIITAAAP-PALSPLGEL 957
EPP S + P P +G L P+ PP P P PL ++ P P + + L
Sbjct: 717 EPPESRVSHLCPEPPETGVSHLRPE--PPKPRVSSLRPEPLETRVSHLRPEPPETGVSHL 774
Query: 958 --EYPFGAKGDSDPESPLAAPILETPISPPPEANCTD--PEP 995
E P E P + + PP + PEP
Sbjct: 775 HPELPKPRVSSLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEP 816
Score = 150 bits (379), Expect = 3e-35
Identities = 189/630 (30%), Positives = 248/630 (39%), Gaps = 109/630 (17%)
Query: 374 PPEPGDTPT-----DEPDALYVACQGQPKGGHVTSM--QPKEPGPLQCEAKP--LGKAGV 424
PPEP TP + P+ + QP V+S+ +P E G +P + +
Sbjct: 199 PPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSL 258
Query: 425 QLEPQ--------LEAPLNEEMPLLPPPEESPLSPPPEESPTS---------PPPEASRL 467
LEP LE P L P P ++ +S E P + P S L
Sbjct: 259 HLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHL 318
Query: 468 SPPPEELPASPL-PEALHLSRPLEESPLSPPPEE--SPLSPPPESSPFSPLEESPLSPPE 524
P P E S L PE + L S PPE S L P P + SPL + PPE
Sbjct: 319 RPEPSETGVSHLHPEP---PKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQ---LPPE 372
Query: 525 ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP----TSPPPEAS----RLSPPP 576
E P + P P +P SPL P P + S PP+ L PP
Sbjct: 373 AGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPK 432
Query: 577 EE-SPMSPPPEESPMS---PPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPED 632
S + P P E+ +S P P +R+ E P + P P + S L P P D
Sbjct: 433 TRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPD 492
Query: 633 SPMSPPPEESPMSPPPEVSRLSPLPV---VSRLSPPPEESPLS----PPPEES-----PT 680
+ +S P P VS L P P VS L P P + +S PPE S P
Sbjct: 493 TGVS---HLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPE 549
Query: 681 SPPPEASRLSPPPEDS---PTSPPPEDSPAS----PPPEDSLMSLPLE--ESPLLPLPEE 731
P S L P P + P P D+ S PP+ + SLP E E+ + L E
Sbjct: 550 PPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPE 609
Query: 732 PQLCPRSEGPHLSPRPEE---PHLSPRPEEPHLSPQAEEP------HLSPQPEEPCLCAV 782
P P + HL P P E HL P P + + EP HL P+P + + ++
Sbjct: 610 P---PETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSL 666
Query: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS---PQPEESHLS----- 834
P EP P+ HL P+P P+T HL P P E +S P+P ++ +S
Sbjct: 667 PPEP---PETGVSHLCPEP------PETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAE 717
Query: 835 -PQSEEPCLSPRPEE---SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPS 890
P+S L P P E SHL PE KP +S +P E PE P G
Sbjct: 718 PPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEP----PETGVSH 773
Query: 891 LSPLLGEPALSEPG-EPPLSPLPEELPLSP 919
L P L +P +S EPP + L L P
Sbjct: 774 LHPELPKPRVSSLHLEPPKTRRVSSLRLEP 803
Score = 108 bits (270), Expect = 1e-22
Identities = 205/732 (28%), Positives = 272/732 (37%), Gaps = 126/732 (17%)
Query: 524 EESPPSPALETPLSPPPEASPLSPPFE-ESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582
E+ PP L+ PL P + E S +E T P E + P E SP
Sbjct: 139 EDMPPDLLLQV-------LKPLDPERKLEDAGSCEGQEKTTDEPTEPGKY-PCGEFSPRP 190
Query: 583 PPPEESPMSPPPEASRLFPPFEESPLSPPPEE---SPLSPPPEASRLSPPPEDSPMSPPP 639
P S + P P P S L P P E S L P P +++S + P +
Sbjct: 191 PETRVSCLPPEP------PKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVS 244
Query: 640 EESPMSPPPEVSRL---------------SPLPVVSRLSPPPEESPLSPPPEESPTSPPP 684
P P +VS L P VS L P P ++ +S E P + P
Sbjct: 245 HLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVP 304
Query: 685 EASRLSPPPEDSPTSPPPEDSPAS---PPPEDSLMSLPLEESP------LLPLPEEPQLC 735
+ P S P P ++ S P P +L+S E P L P P E ++
Sbjct: 305 DLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVS 364
Query: 736 PRSEGP------HLSPRPEEPHLSP-RPEEPH-----LSPQAEEPHLSPQPEEPCLCAVP 783
P + P HL P P + + P RPE P L P+ + +S EP V
Sbjct: 365 PLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVS 424
Query: 784 EEPHLSPQAEGPHLSPQPEEL---HLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840
P+ G HL P+P E HL P+ + +S + EP P+ SHL P+ E
Sbjct: 425 HLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEP---PETGVSHLCPEPPEK 481
Query: 841 CLS---PRPEE---SHLSPELEKPPLSP-RPEKPPEEPGQC---PAPEEL---PLFPPPG 887
+S P P + SHL PE K +S RPE P E G P P ++ L P
Sbjct: 482 DVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPE--PSETGVSHLRPEPPKILVSSLHQAPP 539
Query: 888 EPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAA 947
E S+S L EP E G L P P + + SL P+ PPD L P
Sbjct: 540 ESSVSHLRPEP--PETGVSHLRPEPPKTRMY-----SLRPE--PPDTGVSHLCPEPPKTR 590
Query: 948 PPALSPLGELEYPFGAKGDSDPESPLAAPILETPIS----PPPEANCTDPEPVPPMILPP 1003
+L P E P PE P ET +S PPE + P PP
Sbjct: 591 VSSLPP----EPPETGVSHLCPEPP------ETRVSHLRPEPPETGVSHLRPEPPKTRMY 640
Query: 1004 S--PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSP--PALPLSVPSPLSPIG 1059
S P P S + EP P + S +P P + S P P + S L P
Sbjct: 641 SLRPEPPNTGVSHLCPEP------PKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEP 694
Query: 1060 KVVGVSDEAELH-EMETEKVS--EPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116
GVS LH E +VS E P S P P G P P +
Sbjct: 695 PETGVS---RLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLR 751
Query: 1117 GLGEDTAPLDGIDAPGSQPEPGQTPGS-LASEL---KGSPVLLDPEELAPVTPMEVYPEC 1172
PL+ +PEP +T S L EL + S + L+P + V+ + + P
Sbjct: 752 -----PEPLE-TRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEP-- 803
Query: 1173 KQTAGQGSPCEE 1184
+T S C E
Sbjct: 804 PKTGRVSSLCPE 815
Score = 95.1 bits (235), Expect = 2e-18
Identities = 174/664 (26%), Positives = 232/664 (34%), Gaps = 91/664 (13%)
Query: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647
S +SP A + F E+ L + PL+ P PP + P+ P
Sbjct: 105 SKLSPAQPARKAFVEEVEAQLMT---KHPLAMYPNLGEDMPPDLLLQVL-----KPLDPE 156
Query: 648 PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS---PPPED 704
++ + + P E P E SP P S L P P +P S P P +
Sbjct: 157 RKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPE 216
Query: 705 SPAS----PPPEDSLMSLPLE--ESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE 758
+ S PP+ + SL LE E+ + L EP P+++ L P E +S E
Sbjct: 217 TGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEP---PKTQVSSLHLEPPETGVSHLYLE 273
Query: 759 P------HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEEL---HLSPQ 809
P HL P+ + +S EP VP+ P++ HL P+P E HL P+
Sbjct: 274 PPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPE 333
Query: 810 TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEK--- 866
+ +S + EP P+ SHL P+ E +SP + L PE L P P K
Sbjct: 334 PPKTLVSSLHPEP---PETGVSHLCPEPPETRVSPLRQ---LPPEAGVSHLCPEPPKTRV 387
Query: 867 PPEEPGQCPAPEELPLFPPPGEPSLSPLLGEP-------ALSEPGEPPLSPLPEELPLSP 919
PP P + P PLFP P + +S L EP EP + S L E P
Sbjct: 388 PPLRP-ETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPP--E 444
Query: 920 SGEPSLSPQLMPPDP------LPPPLSPIITAAAPPALSPLGEL--EYPFGAKGDSDPES 971
+G L P+ PP L PP + + P + L E P PE
Sbjct: 445 TGVSHLRPE--PPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEP 502
Query: 972 PLAAPILETPISPPPEANCTDPEPVPPMIL--------PPSPGSPVGPASPIL----MEP 1019
P P P E + P PP IL P S S + P P + P
Sbjct: 503 PKTRVSHLRP--EPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRP 560
Query: 1020 LPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVS 1079
PP+ P C P P + S L P GVS E +VS
Sbjct: 561 EPPKTRMYSLRPEPPDTGVSHLCPEP--PKTRVSSLPPEPPETGVSHLCP--EPPETRVS 616
Query: 1080 --EPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEP 1137
PE P S P P S P P S L + P PE
Sbjct: 617 HLRPEPPETGVSHLRPEPPKTRMYSL---RPEPPNTGVSHLCPEPPKTRVSSLPPEPPET 673
Query: 1138 GQTPGSLASELKGSPVLLDPEELAPVTP----MEVYPECKQTAGQGSPCEEQEEPRAPVA 1193
G S L P L P P ++PE +T E E + +
Sbjct: 674 G------VSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLC 727
Query: 1194 PTPP 1197
P PP
Sbjct: 728 PEPP 731
Score = 61.6 bits (148), Expect = 2e-08
Identities = 145/559 (25%), Positives = 191/559 (34%), Gaps = 118/559 (21%)
Query: 2128 SPTTPAGLS----TSADGFLKPPAGSVP--GPDSPGELFLKLPPQVPAQVPSQDPFGLAP 2181
SP PA + A K P P G D P +L L++ + + +D G
Sbjct: 108 SPAQPARKAFVEEVEAQLMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDA-GSCE 166
Query: 2182 AYPLEPRFPTAPPTYP-----PYPSPTGA---PAQPPMLGASS-RPGAGQPGEFHTTPPG 2232
PT P YP P P T P +PP SS RP + G H P
Sbjct: 167 GQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQ- 225
Query: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEEL 2292
P+ Q S+ L+P + +L PE P + S L PP G S LE +
Sbjct: 226 PPKTQVSSLH--LEPPETGVSHLR-PEPPKT---QVSSLHLEPPETGVSHLYLEPPGTGV 279
Query: 2293 GASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP 2352
P PP + S H E PD+ P R S + P+ G+ P
Sbjct: 280 SHLCPE--PPK-----TRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHP 332
Query: 2353 PPAQALAPSPPSHPDIFRPG-SYTDPYAQPP---LTPRPQPPPPESCCALPPRSLPSDPF 2408
P + L S HP+ G S+ P +PP ++P Q PP L P P
Sbjct: 333 EPPKTLVSS--LHPEPPETGVSHLCP--EPPETRVSPLRQLPPEAGVSHL----CPEPPK 384
Query: 2409 SRV-PASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSR---DPFA 2464
+RV P P++ + SPL P P P+ + + S PP S +P
Sbjct: 385 TRVPPLRPETPKNGVSPLFPEP------------PKTRISNLRSEPPKIGVSHLCLEPPK 432
Query: 2465 PLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS-------GQPPN 2517
RP+PPE G P LH + P +PP
Sbjct: 433 TRGSHLRPEPPET------------GVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPE 480
Query: 2518 FVRS------PGTGAFVGTPSPMRFTFPQAVGEPS------LKPPVPQPGL-----PPPH 2560
S P TG P P + EPS L+P P+ + PP
Sbjct: 481 KDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPE 540
Query: 2561 GINSHFGPGPTLGKPQSTNYTVATGNFHPSGSP-------LGPSSGSTGESYGLSPLRPP 2613
SH P P TG H P L P TG S+ L P PP
Sbjct: 541 SSVSHLRPEPP-----------ETGVSHLRPEPPKTRMYSLRPEPPDTGVSH-LCP-EPP 587
Query: 2614 ----SVLPPPAPDGSLPYL 2628
S LPP P+ + +L
Sbjct: 588 KTRVSSLPPEPPETGVSHL 606
Score = 52.0 bits (123), Expect = 2e-05
Identities = 89/350 (25%), Positives = 124/350 (35%), Gaps = 61/350 (17%)
Query: 2143 LKPPAGSVPG--PDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYP 2200
L+PP V P+ P + L P+ P G++ P P+ T P P
Sbjct: 464 LEPPETGVSHLCPEPPEKDVSHLRPEPPDT-------GVSHLCPEPPK--TRVSHLRPEP 514
Query: 2201 SPTGAP---AQPPMLGASS-------------RPGAGQPGEFHTTP--PGTPRH--QPST 2240
S TG +PP + SS RP + G H P P T + +P
Sbjct: 515 SETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEP 574
Query: 2241 PDPFLKPRCPSLDNLAV----PESPGVGGG---------KASEPLLSPPPFGESRKALEV 2287
PD + CP V PE P G + S PP G S E
Sbjct: 575 PDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEP 634
Query: 2288 KKEELGASSPSYGPPNLGF--VDSPSSGTHLGGLELKTPDVFKAPLTP-----RASQVEP 2340
K + + P PPN G + T + L + P+ + L P R S + P
Sbjct: 635 PKTRMYSLRPE--PPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRP 692
Query: 2341 QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP----RPQPPPPESCC 2396
+ P G+ P P + S + P R S+ P +PP T RP+PP P
Sbjct: 693 EPPETGVSRLHPEPPKTRVSSLHAEPPESRV-SHLCP--EPPETGVSHLRPEPPKPR-VS 748
Query: 2397 ALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS 2446
+L P L + P P++ S P P+P + P T R S
Sbjct: 749 SLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSS 798
Score = 40.8 bits (94), Expect = 0.038
Identities = 77/315 (24%), Positives = 114/315 (36%), Gaps = 51/315 (16%)
Query: 4170 PQPPKPGPVLQSGQGLPGVGIMPTVGQL-RAQLQGVLAKNPQ--LRHLSPQQQQ-QLQAL 4225
P+PPK PV P G+ Q + Q+ + + P+ + HL P+ + Q+ +L
Sbjct: 200 PEPPKT-PVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSL 258
Query: 4226 LMQRQLQQSQAVRQTPPY--------QEPGTQTSPLQGLLGCQPQLGGFPG----PQTGP 4273
++ + PP + P T+ S L +P G P P
Sbjct: 259 HLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHR----EPPETGVPDLCLEPPKSR 314
Query: 4274 LQELGAGPRPQGPPRL-PAPPGALSTGPVLGPVHPTPPPSSPQE--PKRPSQLPSPSSQL 4330
+ L P G L P PP L + +HP PP + P+ P SP QL
Sbjct: 315 VSHLRPEPSETGVSHLHPEPPKTL-----VSSLHPEPPETGVSHLCPEPPETRVSPLRQL 369
Query: 4331 PTEAQLPPTHPGTPKPQGPTLEP--PPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQK 4388
P EA + P PK + P L P P VSP LF +PP +
Sbjct: 370 PPEAGVSHLCPEPPKTRVPPLRPETPKNGVSP--------LFP------EPPKTRISNLR 415
Query: 4389 PEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCA-LGAQSVKREANGEPIGAPGTS- 4446
E + HL P+ ++ EP E + L + K + + P T
Sbjct: 416 SEPPKIGVSHL----CLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGV 471
Query: 4447 NHLLLAGPRSEAGHL 4461
+HL P + HL
Sbjct: 472 SHLCPEPPEKDVSHL 486
Score = 37.0 bits (84), Expect = 0.55
Identities = 97/400 (24%), Positives = 140/400 (35%), Gaps = 80/400 (20%)
Query: 4055 PESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPP------LRLPGQQQQQVSLL 4108
PE T ++P L P+ Q SSL L+PP LR P + QVS L
Sbjct: 200 PEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLR-PEPPKTQVSSL 258
Query: 4109 HTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNT 4168
H + V HL +P PG+ +L P+ P + ++
Sbjct: 259 HL-------------EPPETGVSHLYLEP-------PGTGVSHLC-PEPP---KTRVSHL 294
Query: 4169 GPQPPKPGPVLQSGQGLPGVGIMP---TVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQAL 4225
+PP+ G+P + + P V LR + + HL P+ + L +
Sbjct: 295 HREPPE--------TGVPDLCLEPPKSRVSHLRPE-----PSETGVSHLHPEPPKTLVSS 341
Query: 4226 LMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQG 4285
L V P + P T+ SPL+ L P G P + RP+
Sbjct: 342 LHPE--PPETGVSHLCP-EPPETRVSPLRQL----PPEAGVSHLCPEPPKTRVPPLRPET 394
Query: 4286 P-----PRLPAPP-----GALSTGPVLGPVH----PTPPPSSPQEPKRPSQLPSPSSQLP 4331
P P P PP S P +G H P S P+ P S P
Sbjct: 395 PKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEP 454
Query: 4332 TEAQLPPTHPGTPKPQGPTL--EPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389
+ ++ H P+ L EPP VS + DT S L P +PP +P
Sbjct: 455 PKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSH-LCP-EPPKTRVSHLRP 512
Query: 4390 EQSSLVPGHLDQVNGQVV--------PEASQLSIKQEPRE 4421
E S HL +++ PE+S ++ EP E
Sbjct: 513 EPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPE 552
Score = 35.0 bits (79), Expect = 2.1
Identities = 49/177 (27%), Positives = 62/177 (35%), Gaps = 36/177 (20%)
Query: 4836 EGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDI--LSLLKQESPA-------P 4886
E P + L + P+TG L+ Y+L+ + +S L E P P
Sbjct: 609 EPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPP 668
Query: 4887 EPPTQHSYTYNVSNL-------DVRQLSAPPPE------EPSPPPSPLAPSPASPPTEPL 4933
EPP VS+L V L PPE P PP + ++ A PP +
Sbjct: 669 EPPET-----GVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRV 723
Query: 4934 VELPTEP--------LAEPPVPSPLPLASSPESARPKP-RARPPEEGEDSRPPRLKK 4981
L EP EPP P L P R R PPE G P L K
Sbjct: 724 SHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPK 780
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 158 bits (399), Expect = 2e-37
Identities = 242/997 (24%), Positives = 371/997 (37%), Gaps = 173/997 (17%)
Query: 358 IRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAK 417
+ SV + P S E T + + QG+P+G +Q + P P+ +
Sbjct: 166 VSSVVNKFNPF-DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQG 224
Query: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP---PEASRLSPPPEEL 474
P G+ +Q + ++ +++ PE+ PP P P P+ P +
Sbjct: 225 P-GRDPLQQDGTPKSISSQQ------PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRD 277
Query: 475 PASPLPEALHLSR-----PLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPS 529
+ P + + R P SP PP ++ PP P E+S P
Sbjct: 278 ASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQP----------GHEKSQPG 327
Query: 530 PALETPLSPPPEASPLSPPFEESP-LSPPPEELPTSPPPEASRLSP--PP-----EESPM 581
PA PP + S L+ P + P PP + P + P A L P PP E P
Sbjct: 328 PA-----KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS 382
Query: 582 SPPPEESPMSPPPEASRLFPPFEESPLSPPPEE----SPLSPPP--EASRLSPPPEDSPM 635
S P ++ PP + P + P PP ++ PL+ P ++ +P P +P+
Sbjct: 383 SEQPGPKALAQPPGVGKT-PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 636 SPP-PEESP--MSPPPEVSRLSPLPVVSRLSPPPE-ESPLSPPPEE-SPTSPPPEASRLS 690
P P + P + P + S P PP + P PPP++ P PPP+ +
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPT----KPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 691 PPPEDSP--TSPPPED-SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747
PP P T PPP+ PA P P+ + P + P P Q P S +P
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 748 EEPHLSPRP-EEPHLSPQAEEPHLSPQPEEPC--------LCAVPEEPHLSPQAE----- 793
S +P + P +SP A++P P+ C L VPE+ + + E
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617
Query: 794 --------GPHLSPQPEELHLSPQTEEP---HLSPVPEEPCLSPQPEESHLSPQSEEPCL 842
PHL+ E L L+ Q + L+PVP P P+ + + ++ S
Sbjct: 618 CSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLKTAPVTTTSAVSKS 675
Query: 843 SPRPEESHLSPELEKPP-----LSPRPEKPP-------------EEPGQCPAPEELPLFP 884
SP+P+++ SP+ + P +P P+KPP + Q P + L
Sbjct: 676 SPQPQQT--SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 885 PPGEPSLSPLLGEPALSE--PGEPPLSPLPEELPLSPSGE-----PSLSPQLMPPDPLPP 937
PP EPS+ + +++ P +P + +L S S PS Q + P
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 938 PLSPIITAAAPPALS--PLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEP 995
PL T +A P+ S P GE PF +K P S + I+ P P + +
Sbjct: 794 PLK---TDSAKPSQSFPPTGEKVSPFDSKAIPRPASD--SKIIS---HPGPSSESKGQKQ 845
Query: 996 VPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSP- 1054
V P+ P SP P P+ P+ SP P +VP+P
Sbjct: 846 VDPVQKKEEPKKAQTKMSP------KPDAKPM------PKGSPTPPGPRPTAGQTVPTPQ 893
Query: 1055 LSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT-----SPLPSPMGDLSCPAPSPA 1109
SP + L + S+P P + + + S +L A P
Sbjct: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
Query: 1110 PALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVY 1169
P G AP+ AP SQP Q P + AP P +
Sbjct: 954 PHSQSGPG-----APMKQAPAP-SQPPTSQGPPKSTGQ-------------APPAPAKSI 994
Query: 1170 PECKQTAGQGSPCEEQEEPRAPVAPT---PPTLIKSDIVNEISNLSQGDASASFPGSEPL 1226
P K+T +P E+ EP+A APT T K + + +L+ A P L
Sbjct: 995 PVKKETK---APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLP--TKL 1049
Query: 1227 LGSPDPEGGGSL-SMELGVSTDVSPARDEGSLRLCTD 1262
SP PE L EL + ++D + CT+
Sbjct: 1050 EKSPKPESTCPLCKTELNIG-----SKDPPNFNTCTE 1081
Score = 115 bits (287), Expect = 2e-24
Identities = 236/1108 (21%), Positives = 363/1108 (32%), Gaps = 193/1108 (17%)
Query: 442 PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASP--------------------LPE 481
P ESP +E +S PP+ S P P PA P P
Sbjct: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGR-PAQPGLSKSRTTDTFRSEQKLPGRSPS 131
Query: 482 ALHLSRPLEESPLSPPPEESPL--------------SPPPESSPFSPLEESPLSPPEESP 527
+ L + L + S + S + +PF + +S S E +
Sbjct: 132 TISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTK 191
Query: 528 PSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP------EASRLSPPPEESPM 581
++ P + PP ++ P P P++ P S S PE+
Sbjct: 192 KQKVVQKEQGKP--EGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKS 249
Query: 582 SPPPEESPMSPP---PEASRLFPPFEESPLSP--------------PPEESPLSPPPEAS 624
PP P+ P P+ P + P P SP PP +
Sbjct: 250 QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
Query: 625 RLSPPPEDSPMSPPPEESPMSPPPEVSRLS------PLPVVSRLSPP----PEESPLSP- 673
PP P + P PP + S L+ P V + PP P PL P
Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA 369
Query: 674 -PP-----EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP 727
PP E P+S P L+ PP T P + PA PP + PL + P L
Sbjct: 370 KPPAQQTGSEKPSSEQPGPKALAQPPGVGKT-PAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428
Query: 728 LPEE---PQLCP-RSEGPHLSP-------RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776
P + P P + GP P + P L A+ P P P +
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 777 PCLCAVPEEP-HLSPQAEGPHLSPQPEEL--HLSPQTEEPHLSPVPEEPCLSPQPEESHL 833
P P++P P ++ P + P + P ++P + P + S +P
Sbjct: 489 P----PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544
Query: 834 SPQSEEPCLSPRP-EESHLSPELEKPPLSPRPEKPPEEP------GQCPAPEELPLFPPP 886
SP S +P ++ L+ P +SP ++PP + C E L P
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEK 604
Query: 887 GEPSLSPLLGEPALSEPG---EPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPP---LS 940
+ S G P L+ + E L L+ + +L L P P P +
Sbjct: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA 664
Query: 941 PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMI 1000
P+ T +A SP + P K D+ P+ L+ PEP P
Sbjct: 665 PVTTTSAVSKSSPQPQQTSP---KKDAAPKQDLSKA----------------PEPKKP-- 703
Query: 1001 LPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGK 1060
PP P SP PP+ L + + + S PS+ P++ P P K
Sbjct: 704 -PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSE--QDKAPVADDKPKQP--K 758
Query: 1061 VVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGE 1120
+V + + T K P + P D + P+ S F GE
Sbjct: 759 MVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQS-------FPPTGE 811
Query: 1121 DTAPLD--GIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQ 1178
+P D I P S + PG +SE KG V P++ E K+ +
Sbjct: 812 KVSPFDSKAIPRPASDSKIISHPGP-SSESKGQ---------KQVDPVQKKEEPKKAQTK 861
Query: 1179 GSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDP-EGGGS 1237
SP + +P +PTPP + A + P + SP P E
Sbjct: 862 MSP-KPDAKPMPKGSPTPPG-------------PRPTAGQTVPTPQQ---SPKPQEQSRR 904
Query: 1238 LSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPAR 1297
S+ LG TD ++ T L S+ A IS G+ G S
Sbjct: 905 FSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS---TAGQPGPHSQSGPG 961
Query: 1298 SRIKQGRSSSFP----GRRRPRGGAHGG-----------RGRGRARLKSTASSIETLVVA 1342
+ +KQ + S P G + G A + +L+ A T+
Sbjct: 962 APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT 1021
Query: 1343 DIDSSPSKEEEEEDDDTMQNTVVLFSNTDKFVLMQDMCVVCG---SFGRGAEGHLLACSQ 1399
+ + P ++ + VL + +K + C +C + G + C++
Sbjct: 1022 ETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTE 1081
Query: 1400 CSQCYHPYCVNSKITKVMLLKGWRCVEC 1427
C C + + ++ W C+ C
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNC 1109
Score = 104 bits (259), Expect = 3e-21
Identities = 186/786 (23%), Positives = 263/786 (33%), Gaps = 134/786 (17%)
Query: 518 SPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
S LS E + + P + P P ESP +EL +S PP+ S
Sbjct: 46 SQLSEEERRQIAAVMSRAQGLPKGSVP--PAAAESPSMHRKQELDSSHPPKQSG------ 97
Query: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637
PP P P SR F P S +S SR E
Sbjct: 98 ----RPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMM 153
Query: 638 PPEESPMSPPPEVS----RLSPLPVVSRLSPPPEESP----------------LSPPPEE 677
P S ++ VS + +P ++S EE+ + PP ++
Sbjct: 154 PGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ 213
Query: 678 SPTSPPPE---------------ASRLSPPPEDSPTSPPPEDSPASPP---PEDSLMSLP 719
P P P+ S S PE + PP P P P+ LP
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP 273
Query: 720 LEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL-SPRPEEPHLSPQAEEPHLSPQPEEPC 778
L+ P ++ + P P +P + P P +P P + H QP
Sbjct: 274 LQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP---PAQQPGHEKSQPG--- 327
Query: 779 LCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE 838
P +P P L+ QP + P + P + P +P L P + + +
Sbjct: 328 ----PAKPPAQPSGLTKPLAQQPGT--VKPPVQPPGTTKPPAQP-LGPAKPPAQQTGSEK 380
Query: 839 EPCLSPRPEESHLSPELEKPPL-SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897
P P+ P + K P P P KPP + Q P+ L P P+ +P +
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ--QVGTPKPLAQQPGLQSPAKAPGPTK 438
Query: 898 PALSEPGEPPLSPLPEELPLSPSGE---PSLSPQLMPPDPLPPPLSPIITAAAPPALSPL 954
+ +PG P P + P S + P+ P +P PPP P A PP P
Sbjct: 439 TPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP--GPAKPPPQQP- 494
Query: 955 GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASP 1014
G + P G + P P +P P T P P PS P PA P
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSPQQP----GSTKPPSQQPGSAKPSAQQP-SPAKP 549
Query: 1015 ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEME 1074
+ P L P PS PP+ L P + P+ + E LH E
Sbjct: 550 SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL--PKTICPLCN----TTELLLHVPE 603
Query: 1075 TEKVSE-PECPALEPSATSPLPSPM-------------------GDLSCPAPSPAPALDD 1114
+ EC S P+P GDL+ SP P L
Sbjct: 604 KANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL-- 661
Query: 1115 FSGLGEDTAPLDGIDAPG-SQPEPGQTPG----------SLASELKGSPVLLDPEEL--A 1161
TAP+ A S P+P QT S A E K P L+ L +
Sbjct: 662 ------KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715
Query: 1162 PVTPMEVYPECKQTAGQGSPCE---EQEEPRAPVA---PTPPTLIK--SDIVNEISNLSQ 1213
P + PE + P E E+ +APVA P P ++K +D+V+ S ++
Sbjct: 716 PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK 775
Query: 1214 GDASAS 1219
D +S
Sbjct: 776 PDIPSS 781
Score = 92.4 bits (228), Expect = 1e-17
Identities = 178/816 (21%), Positives = 269/816 (32%), Gaps = 181/816 (22%)
Query: 352 AQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPK-------------- 397
AQ + A+Q T S+ +P PT P A QG PK
Sbjct: 541 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH 600
Query: 398 -------------GGHVTSMQPKEPGP----------LQCEAKPLGKAGVQLEPQLEAPL 434
V S+ P P L C+ K + P P
Sbjct: 601 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660
Query: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEAS---RLSPPPEELPASPLPEALHLSRPLEE 491
+ P+ S SP P++ TSP +A+ LS PE PL + L
Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQ--TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLS--PPF 549
PP +S P P P P E+ ++ P P + P + +S + P
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Query: 550 EESPLSPPPEELPTSPPPEASRLSP----PPEESPMSPPPEESPMSPPPEASRLFPPFEE 605
S + EE T+PP + P PP +SP ++ P ++ + P
Sbjct: 779 PSSKVQSQAEE-KTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPS 837
Query: 606 SPLSPPPEESPL----SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSR 661
S + P+ P +++SP P+ PM P +P P P + P P +
Sbjct: 838 SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPM-PKGSPTPPGPRPTAGQTVPTP---Q 893
Query: 662 LSPPPEE---------SPLSPPPEESPTSP------------------------------ 682
SP P+E ++ P+ PT+P
Sbjct: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
Query: 683 ------PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736
P + +P P PTS P S PP + S+P+++ P E +L P
Sbjct: 954 PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA-KSIPVKKETKAPAAE--KLEP 1010
Query: 737 RSE-GPHLSPRPEEPHLSPRPEEPHLSPQAEEPHL------SPQPEEPC-LCAV------ 782
++E P + E P + L+ + ++ L SP+PE C LC
Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS 1070
Query: 783 PEEPHLSPQAE-------------GPHLSPQPEELHLSPQTEEP---------HLSPVPE 820
+ P+ + E PHL+ E L L+ QT+ + P P
Sbjct: 1071 KDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPS 1130
Query: 821 EPCLSPQPEESHLSPQSEEPCLSP-----RPEESHLSPELEKPPLSPRPEKPPEEPGQCP 875
P SP P + S S++ + P + +E + E EK L E+ +
Sbjct: 1131 GPKASPMPVPTESS--SQKTAVPPQVKLVKKQEQEVKTEAEKVIL--------EKVKETL 1180
Query: 876 APEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMP---- 931
+ E++P + L + S E PLPEE L P E S + P
Sbjct: 1181 SMEKIPPMVTTDQKQEESKLEKDKASALQEK--KPLPEEKKLIPEEEKIRSEEKKPLLEE 1238
Query: 932 --PDPLPPPLSPIITAAAPP-------------ALSPLGELEYPFGAKGDSDPESPLAAP 976
P P L P +AP A L P + P++ +
Sbjct: 1239 KKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGL 1298
Query: 977 ILETPISPPPEANCT----DPEPVPPMILPPSPGSP 1008
TP S P E + T +P PP P P
Sbjct: 1299 PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334
Score = 85.9 bits (211), Expect = 1e-15
Identities = 251/1123 (22%), Positives = 366/1123 (32%), Gaps = 204/1123 (18%)
Query: 1929 GLPLGNLPSSSPMDSYPGLCQSPFLDSRE--RGGFFSPEPGEPDSPWTGSGGTTPSTPTT 1986
GLP G++P ++ P + + LDS + P+PG P P TT + +
Sbjct: 65 GLPKGSVPPAAAES--PSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSE 122
Query: 1987 PTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSSRCKQIM 2046
G + S R + EE S++ P + +N S ++
Sbjct: 123 QKLPGRSPSTISLKESKSRTDLKEE--HKSSMMPGFLSEVNA----------LSAVSSVV 170
Query: 2047 KLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKV--GDIARKTDRPALHL 2104
+ P+ + + K QK + + K + + ++ +P
Sbjct: 171 NKFN--------PFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP---- 218
Query: 2105 RIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP 2164
IP Q G G P T S P + + G KP G P + KLP
Sbjct: 219 -IPKQQGP-GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD---HAKLP 273
Query: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGA---------------PAQP 2209
Q A P + ++P P+ P+ PP PT PA+P
Sbjct: 274 LQRDASRPQTKQADIVRGESVKPSLPS--PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP 331
Query: 2210 PMLGAS-SRPGAGQPGEFH--TTPPGT---------PRHQPSTPDPFLKPRCPSLDNLAV 2257
P + ++P A QPG PPGT P P+ KP A+
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL 391
Query: 2258 PESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGP-PNLGFVDSPSSGTHL 2316
+ PGVG A +P + PP + + ++ G SP+ P P V P G
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP-GLQSPAKAPGPTKTPVQQPGPG--- 447
Query: 2317 GGLELKTPDVFKAPLTPRASQVEPQSPGLGLR------PQEPPPAQALAPSPPS-HPDIF 2369
K P P A Q P P L PQ+P PA+ P S P
Sbjct: 448 -----KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 2370 RPGSYTDPYAQP-PLTPRPQ------PPPPESCCALPPRSLPS--DPFSRVPASPQSQSS 2420
+PGS P QP P P PQ PP + A P PS P ++ P SQ+
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 2421 SQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR--PQSRDPFAPLHKPPRPQPPEVA 2478
S PL P +S A +PPS+ P++ P + P +
Sbjct: 563 SGKPLQPPTVSPSA----------------KQPPSQGLPKTICPLCNTTELLLHVPEKAN 606
Query: 2479 FKAGSLAHTSL-GAGGF---------------PAALPAGPAGELHAKVPSGQPPNFVRSP 2522
F + T++ GF + G+L A VPS P +P
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDL-APVPSSPQPKLKTAP 665
Query: 2523 GT---GAFVGTPSPMRFTFPQAVGEPSLK-PPVPQPGLPPPHGINSHFGPGPTLGKPQST 2578
T +P P + T P+ P P+P PPP PTL
Sbjct: 666 VTTTSAVSKSSPQPQQ-TSPKKDAAPKQDLSKAPEPKKPPP------LVKQPTL------ 712
Query: 2579 NYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGI 2638
GSP + E+ LS PP P+ P Q
Sbjct: 713 -----------HGSP-SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ---- 756
Query: 2639 TSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRN 2698
K P T + SS + P P SQ E EK + Q
Sbjct: 757 ----PKMVKPTTDLVSSSSATTKPDI--PSSKVQSQAE-EKTTPPLKTDSAKPSQSFPPT 809
Query: 2699 TLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSG 2758
++ + + A+ P S S P S+GQ Q K P K
Sbjct: 810 ----GEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEE-----PKK--- 857
Query: 2759 PILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLW 2818
+ ++S P P A P M S G Q P P P Q+Q + +
Sbjct: 858 ---------AQTKMS-PKPDAKP--MPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRF 905
Query: 2819 QQQQATAATSMRFAMSARFPSTPGPELGRQALG---SPLAGISTRLPGPGEPVP----GP 2871
+ + + P+TP + + G S + S + G+P P GP
Sbjct: 906 SLNLGSITDAPKSQ-----PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 2872 AGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPP 2931
P + GP + GQ PP + PV ++ A E L A
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKS--TGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
Query: 2932 QK-PSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTEL 2973
++ + P + +S T + LPT LE +P S+ L
Sbjct: 1019 KRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
Score = 84.7 bits (208), Expect = 2e-15
Identities = 188/829 (22%), Positives = 280/829 (33%), Gaps = 146/829 (17%)
Query: 3954 QLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPG 4013
+ Q++ ++Q+ Q++Q + G++ P+ +QQ GPG PLQ +P
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQ---GPGRD--PLQQDGTPK 237
Query: 4014 ALGPTLLLTGKEQNTVDPAVSSEATEGPST-HQGGPLAIGT----TPESMATEPGEVKPS 4068
++ K Q T+ P T H PL T ++ VKPS
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297
Query: 4069 LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEAS 4128
L S+ + QP P +PP + PG ++ Q G SG + +
Sbjct: 298 LPSPSKPPIQQPTPG--------KPPAQQPGHEKSQ------PGPAKPPAQPSGLTKPLA 343
Query: 4129 SVPHLLAQPSVSLGDQPGSMTQ---NLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGL 4185
P + P QP T+ LGP +P ++ + P P + Q
Sbjct: 344 QQPGTVKPPV-----QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP---- 394
Query: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTP---P 4242
PGVG P AQ G P QQ L Q+ QS A P P
Sbjct: 395 PGVGKTP------AQQPGPAKP--------PTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 4243 YQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVL 4302
Q+PG P Q Q G QTGP + P P PP P PG P
Sbjct: 441 VQQPGPGKIPAQ-----QAGPGKTSAQQTGPTKPPSQLPGPAKPP--PQQPGPAKPPPQQ 493
Query: 4303 GPVHPTPPPSSPQEPKRPSQLPSP---SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVS 4359
P PP P K P Q P P S Q P + P PG+ KP +P P +
Sbjct: 494 -PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ--QPSPAK-- 548
Query: 4360 PAAAQLADTLFSKGLG-PWDPPDNLAETQKPEQSSLVPGHLDQVNGQV----VPEASQLS 4414
P+A Q + G G P PP ++P L N VPE + +
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 4415 IKQEPREEPCALGAQS-----------------VKREANGEPIGAPGTSNHLLLAGP--- 4454
E + C+L + +KR G+ P + L P
Sbjct: 609 TCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTT 668
Query: 4455 -----------------RSEAGHLLLQKLLRAKN----VQLSTGRGSEGLRAEINGHIDS 4493
+ A L K K V+ T GS +A+ DS
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728
Query: 4494 KLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLK 4553
K PS ++ A +PK V+ +D LVSS K D + ++
Sbjct: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTD-LVSSSSATTKPD---IPSSKVQ 784
Query: 4554 QLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTK 4613
+E + PL + + S F P G + F S A+P P S++++
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQS-FPPTG---------EKVSPFDSKAIPR-PASDSKIISH 833
Query: 4614 NNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKS 4673
S+ + P +K ++P + PK + + T
Sbjct: 834 PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT----- 888
Query: 4674 LDLLAALPTP-----PHNQTEDVRMESDEDSDSPDSIVPASSPESILGE 4717
+PTP P Q+ + +D+P S P + E++ G+
Sbjct: 889 ------VPTPQQSPKPQEQSRRFSLNLGSITDAPKS-QPTTPQETVTGK 930
Score = 72.8 bits (177), Expect = 9e-12
Identities = 288/1380 (20%), Positives = 441/1380 (31%), Gaps = 295/1380 (21%)
Query: 3856 QQQQQQQQHQQQGSMAGLSHLQQS----LMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQ 3911
QQQ + +QQG G LQQ +S K+ +QP G+ + +Q Q Q
Sbjct: 212 QQQPPKPIPKQQGP--GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 3912 LQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQ 3971
+ Q+ + Q Q ++ + + L + +QQ QQ ++ Q
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 3972 QQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDP 4031
+ Q L P QQ PG P+Q PG P G + P
Sbjct: 330 KPPA----QPSGLTKPLAQQ-------PGTVKPPVQ---PPGTTKPPAQPLGPAK----P 371
Query: 4032 AVSSEATEGPSTHQGGPLAIGTTP---ESMATEPGEVKPSLS--GDSQLLLVQP------ 4080
+E PS+ Q GP A+ P ++ A +PG KP G + L QP
Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA 431
Query: 4081 -QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSV 4139
P P + +Q P ++P QQ AG G +G + S +P P
Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQ---------AGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
Query: 4140 SLG------DQPGSMTQNLL-----------------GPQQPMLERPMQNNTG------- 4169
G QPGS PQQP +P G
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ 542
Query: 4170 -PQPPKPG------PVLQSGQGLP--------------GVGIMPTVGQLRAQLQGVLAKN 4208
P P KP PV Q+G G P G+ T+ L +L
Sbjct: 543 QPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL-CNTTELLLHV 601
Query: 4209 PQLRHLS------------------PQQQQQLQALLMQRQLQQSQA--VRQTPPYQEPGT 4248
P+ + + P + + L + Q++++ + P +P
Sbjct: 602 PEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661
Query: 4249 QTSPLQGLLGC-----QPQLGGFPGPQTGPLQELGAGPRPQGPPRL-------------- 4289
+T+P+ QPQ P P Q+L P P+ PP L
Sbjct: 662 KTAPVTTTSAVSKSSPQPQQTS-PKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA 720
Query: 4290 PAPPGALSTGPVLGPVHPTPP------PSSPQEPKRPSQLPS----------------PS 4327
PP A S P P+ P P + +PK+P + PS
Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Query: 4328 SQLPTEAQ---LPPTHPGTPKPQ---GPTLE----------PPPGRVSPAAAQLADTLFS 4371
S++ ++A+ PP + KP PT E P P S + + S
Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840
Query: 4372 KGLGPWDPPDNLAETQK--------------PEQSSLVPGHLDQVNGQVVPEASQLSIKQ 4417
KG DP E +K P+ S PG GQ VP Q S K
Sbjct: 841 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA-GQTVPTPQQ-SPKP 898
Query: 4418 EPREEPCALGAQSVKREANGEPIGAPGT----------------SNHLLLA---GPRSEA 4458
+ + +L S+ +P T SN + A GP S++
Sbjct: 899 QEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958
Query: 4459 GHLLLQKLLRA-------KNVQLSTGRGSEGLRAEINGHIDSKLAG---LEQKLQGTPSN 4508
G K A + STG+ I ++K LE K + P+
Sbjct: 959 GPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
Query: 4509 KEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPA 4568
K +KP K + A + KL K E+ K EL++ P
Sbjct: 1019 KRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP---KPESTCPLCKTELNIGSKDPPN 1075
Query: 4569 ITANFSLFAPFGSGCPVNGQSQLRGAFGSGAL--PTGPDYYSQLLTKNNLSNPPTPPSSL 4626
+ C N L L T QL + P+ P +
Sbjct: 1076 FNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKAS 1135
Query: 4627 P-PTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPH 4685
P P P S QK V P +L + + + L E S++ + + T
Sbjct: 1136 PMPVPTESSSQK--TAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 4686 NQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIP--- 4742
Q E+ ++E D+ S A + L EE P R E++ L P
Sbjct: 1194 KQ-EESKLEKDKAS--------ALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPE 1244
Query: 4743 ---LIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGV 4799
L+P A P+ + + L +V EK +G + + G+
Sbjct: 1245 DKKLLPEAKTSA-PEEQKHDLLKSQVQ-----IAEEKLEGRVAPKTVQEGKQPQTKMEGL 1298
Query: 4800 MVAVAELLSMKIPNSYEVL--FPESPARA---GTEPKKGEAEGPGGKEKGLEGKSP---- 4850
+ L + + + + P+ P A EP K + E K + P
Sbjct: 1299 PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQ 1358
Query: 4851 ---DTG--PDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQ 4905
DTG D + +P + DIL LK++S + E S D+ +
Sbjct: 1359 GLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPS-------SPSDLAK 1411
Query: 4906 LSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPS---PLPLASSPESARPK 4962
L + S LA + T+P P +P + S L + S E +
Sbjct: 1412 LESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIK-- 1469
Query: 4963 PRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRP 5022
E ++ R KK Q+ +D +E +EF++ + T P
Sbjct: 1470 -------ESQEERKDTFKK-------------DSQQDIPSSKDHKEKSEFVDDITTRREP 1509
Score = 65.5 bits (158), Expect = 1e-09
Identities = 109/486 (22%), Positives = 171/486 (35%), Gaps = 75/486 (15%)
Query: 4023 GKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLV---- 4078
G + +V PA A E PS H+ L P+ P +P+ G S+
Sbjct: 65 GLPKGSVPPA----AAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR 120
Query: 4079 --QPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQ 4136
Q P PS++ L+ +++ S + L + SS P L
Sbjct: 121 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180
Query: 4137 PSVSLGDQ---PGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQ-------SGQGLP 4186
S + ++ + Q G + +++ P+Q QPPKP P Q G P
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ----QPPKPIPKQQGPGRDPLQQDGTP 236
Query: 4187 GVGIMPTVGQLRAQLQGV------LAKNPQLRHLS-PQQQQQLQALLMQRQLQQSQAVRQ 4239
++++Q G + PQ H P Q+ + Q + + ++V+
Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP 296
Query: 4240 T------PPYQEPGTQTSPLQ--GLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPA 4291
+ PP Q+P P Q G QP P +G + L P PP
Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP--VQ 354
Query: 4292 PPGALSTGPVLGPVHPTPPPSSPQEPKRP-SQLPSPS------------SQLPTEAQLPP 4338
PPG +T P P+ P PP+ ++P S+ P P +Q P A+ P
Sbjct: 355 PPG--TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412
Query: 4339 THPGTPKP-----------------QGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPD 4381
GTPKP + P +P PG++ PA ++ GP PP
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI-PAQQAGPGKTSAQQTGPTKPPS 471
Query: 4382 NLAETQKPEQSSLVPGH-LDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPI 4440
L KP P Q G P + Q + P ++P + + P
Sbjct: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 4441 GAPGTS 4446
PG++
Sbjct: 532 QQPGSA 537
Score = 59.7 bits (143), Expect = 8e-08
Identities = 76/268 (28%), Positives = 95/268 (35%), Gaps = 32/268 (11%)
Query: 454 EESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFS 513
+E P S P S P LPA P P S + P PPP P PPP P
Sbjct: 2369 QEKPASQLPSGS---PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Query: 514 PLEESPLSPPEESPPSPALETPLSPPPEASPL--------SPPFEESPLSPPPEELPTSP 565
PL P SP P L T SP A+PL + S P T+P
Sbjct: 2426 PL-PPPTSPKPTILPKKKL-TVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
Query: 566 PPEASRLSPPPEESPMS------PPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP 619
PP + P P P P P + P++P P +L P + P P+ + LS
Sbjct: 2484 PP----VPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL-PTTTQKPTDIHPKPTGLSL 2538
Query: 620 PPEASRLSPPPED----SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
+ D SP SP S S P L+ VV L P +P
Sbjct: 2539 TSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITL-PSEPGTPTDSSA 2597
Query: 676 EESPTSPP---PEASRLSPPPEDSPTSP 700
++ TS P P +S P S P
Sbjct: 2598 SQAITSWPLGSPSKDLVSVEPVFSVVPP 2625
Score = 58.5 bits (140), Expect = 2e-07
Identities = 212/1083 (19%), Positives = 361/1083 (33%), Gaps = 169/1083 (15%)
Query: 2611 RPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMS 2670
+PP +P G P G + P + + P PGT P +
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP-------------PGTGKP-IQ 259
Query: 2671 GLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFE 2730
G +QT Q +L +QR+ R + + A G P PS P +
Sbjct: 260 GPTQTP---QTDHAKL-------PLQRDASRPQTKQADIVRGESVKPSL--PSPSKPPIQ 307
Query: 2731 QLSRGQTPFAGTQDKSSLVG--LPPSKLSG--------------PILGPGSF-PSDDRLS 2773
Q + G+ P + S G PP++ SG P+ PG+ P L
Sbjct: 308 QPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG 367
Query: 2774 RPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQ------QQQLWQQQQATAAT 2827
PPA + + S + G + P G P QQ QQ+ +
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKAL--AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP 425
Query: 2828 SMRFAMSARFPS-TPGPELGRQALGSPLAG---ISTRLPGPGEP---VPGPAGPAQFIEL 2880
++ A P+ TP + G + + AG S + GP +P +PGPA P
Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP------ 479
Query: 2881 RHNVQKGLGPGGTPFPGQGPPQRP-RFYPVSEDPHRLAPEGLRGLAVSGLPPQKPS-APP 2938
P P P + PPQ+P P S+ P P PPQ+P A P
Sbjct: 480 ---------PPQQPGPAKPPPQQPGSAKPPSQQPGSTKP-----------PPQQPGPAKP 519
Query: 2939 APELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFD 2998
+P+ S P G P+ + PS+ + P++ P + P +
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ--STKPVSQTGSGKPLQPPTVSPSAK 577
Query: 2999 AHKALEDDEELAHLGLGVDVAKGDDE---LGTLENLETN---------DPHLDDL----- 3041
+ + + L ++ E T +T +PHL ++
Sbjct: 578 QPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLC 637
Query: 3042 --------LNGDEFDLLAYTDPELDTG-----DKKDIFNEHLRLVESANEKAEREALLRG 3088
L GD + + P+L T + + + A ++ L +
Sbjct: 638 LNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKA 697
Query: 3089 VEPGPLGPEERPP-----PAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEP 3143
EP P + P P+A A +P A L + P E PS P +
Sbjct: 698 PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE-----PSVPSEQDKAPVADD 752
Query: 3144 APAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSG 3203
P + +KP ++ S T P S +A T PS
Sbjct: 753 KPKQPKM---VKPTTDLVSSSSAT--TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 3204 PGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKK 3263
P G + +S A+ P AS ++ S+ ++ + +KKE KK
Sbjct: 808 PTGEKV---SPFDSKAIPRP----ASDSKIISHPGPSSESKGQKQVDPV---QKKEEPKK 857
Query: 3264 QQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQP 3323
Q ++ P + + P P ++P SP ++ SL L
Sbjct: 858 AQ--TKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA 915
Query: 3324 GLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMG 3383
QP P + L ++ S +++S GQ G Q + Q P
Sbjct: 916 PKSQPTTPQETVTGKL---FGFGASIFSQASNLIS--TAGQPGPHSQSGPGAPMKQAPAP 970
Query: 3384 TMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGS 3443
+ PP+ P+ P K A + ++P A+ + +K +
Sbjct: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAE-QAPTVKRTETEKKPPP 1029
Query: 3444 IGVAPGMNRQ-QVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQ--- 3499
I + + + Q ++L +L P + + E + G P N T +
Sbjct: 1030 IKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK---TELNIGSKDPPNFNTCTECKNQV 1086
Query: 3500 ----GVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGRE 3555
G + +EWL Q + + Q+G RK A + + E
Sbjct: 1087 CNLCGFNPTPHLTEIQEWLCLNCQ----TQRAISGQLGDIRKMPPAPSGPKASPMPVPTE 1142
Query: 3556 FPE---ADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQ 3612
A ++KLV +Q+ +++ + ++V ++ + T M + Q+Q++ + ++
Sbjct: 1143 SSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEK 1202
Query: 3613 HSA 3615
A
Sbjct: 1203 DKA 1205
Score = 57.4 bits (137), Expect = 4e-07
Identities = 77/279 (27%), Positives = 104/279 (37%), Gaps = 48/279 (17%)
Query: 470 PPEELPASPLPEALHLSRPL------EESPLSPPPEESPL--SPPPESSPF---SPLEES 518
PP + A P+ E L + +E P S P SP S P + PF S L+ S
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 519 PLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE 578
PP PP PPP P PP PPP PTSP P + P +
Sbjct: 2403 AQPPPPPPPP---------PPPPPPPPPPP-------PPPLPPPTSPKP---TILPKKKL 2443
Query: 579 SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP 638
+ SP +P+ + L P +PPP + S P +
Sbjct: 2444 TVASPVTTATPLFDAVTTLETTAVLRSNGL-PVTRICTTAPPPVPPKPSSIPSGLVFTHR 2502
Query: 639 PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPED--- 695
PE P PP ++P PV+ +L P + P P+ + S + D
Sbjct: 2503 PE--PSKPP-----IAPKPVIPQL-PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKL 2554
Query: 696 -SPTSP-PPEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732
SPTSP P + +SP SL E ++ LP EP
Sbjct: 2555 PSPTSPLSPHSNKSSPRFSKSL----TETYVVITLPSEP 2589
Score = 54.3 bits (129), Expect = 3e-06
Identities = 223/1063 (20%), Positives = 335/1063 (31%), Gaps = 160/1063 (15%)
Query: 3553 GREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQ 3612
GR+ + D + ++Q KI+ Q K + T K Q+ + Q +Q
Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQ 285
Query: 3613 HSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPF 3672
V S S LP P P PP Q G + PG P QP G
Sbjct: 286 ADIVRGESVKPS------LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG-- 337
Query: 3673 LNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQ 3732
L LAQQ G P G P + LGP Q Q
Sbjct: 338 LTKPLAQQ-----PGTVKPPVQPPGTTKP---PAQPLGPAKPPAQ--------------Q 375
Query: 3733 KLQQQQQQQQQQQHLLGQ---VAIQQQQQQGPGVQTNQALG-PKPQGLMPPSSHQGLLVQ 3788
++ +Q L Q V QQ GP Q +G PKP P GL
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP-----GLQSP 430
Query: 3789 QLSPQPPQGPQGMLGPAQVAVLQQQHPG-----ALGPQGPHRQVLMTQSRVLSSPQLAQQ 3843
+P P + P GP ++ QQ PG GP P Q+ P A+
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPA-QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489
Query: 3844 GQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQ 3903
G +QQ + QQ A S Q Q SA+P QQ
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP-----SAQQP 544
Query: 3904 QQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQ--QLQQQQQQLQQQQQQ 3961
+ Q + Q + LQ + +Q Q + L + L ++
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEK 604
Query: 3962 QQQQFQQQQQQQQMGL--LNQSRTLLSPQQ----QQQQQVALGPGMPAKPLQHFSSPGAL 4015
+ Q L N + L ++ Q + ALG + P SSP
Sbjct: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP----SSPQPK 660
Query: 4016 GPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQL 4075
T +T + V + P + PE P +P+L G
Sbjct: 661 LKTAPVT--TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 4076 LLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA 4135
QP P+ SL P + P +Q ++ +
Sbjct: 719 KAKQP---PEADSLSKPAPPKEPSVPSEQ---------------DKAPVADDKPKQPKMV 760
Query: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVG 4195
+P+ L + T+ P P + Q PP + Q P G +
Sbjct: 761 KPTTDLVSSSSATTK----PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 4196 QLRAQLQGVLAKNPQLRHLSPQQ----QQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTS 4251
+A + + + + H P Q+Q+ + + + +++Q P +P + S
Sbjct: 817 DSKA-IPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGS 875
Query: 4252 PLQGLLGCQPQLG-GFPGPQTGPLQE-------LGAGPRPQGPPRLPAPPGALSTGPVLG 4303
P G +P G P PQ P + L G P P P TG + G
Sbjct: 876 PTPP--GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFG 933
Query: 4304 -------------PVHPTPPPSSPQEPKRP-SQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349
P P S P P Q P+PS PPT G PK G
Sbjct: 934 FGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ--------PPTSQGPPKSTGQ 985
Query: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHL-DQVNGQVVP 4408
P P + P + K +P A T K ++ P + D + P
Sbjct: 986 A-PPAPAKSIPVKKETKAPAAEK----LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040
Query: 4409 EASQLSIKQEPREEP---CALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLL--- 4462
+ + L K E +P C L K E N IG+ N +++ +L
Sbjct: 1041 QKAVLPTKLEKSPKPESTCPL----CKTELN---IGSKDPPNFNTCTECKNQVCNLCGFN 1093
Query: 4463 ----LQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPL 4518
L ++ + T R G +I +K+ PS + A+ P+
Sbjct: 1094 PTPHLTEIQEWLCLNCQTQRAISGQLGDI------------RKMPPAPSGPK--ASPMPV 1139
Query: 4519 TPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSL 4561
+ + A V KK +E A + +L+++K+ LS+
Sbjct: 1140 PTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSM 1182
Score = 54.3 bits (129), Expect = 3e-06
Identities = 57/218 (26%), Positives = 95/218 (43%), Gaps = 10/218 (4%)
Query: 3826 QVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSG 3885
+V+ +S +L P+ +Q Q L R + ++ +QQ+ ++ L +Q +
Sbjct: 3193 EVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEE-----LEWERQEIQRFRE 3247
Query: 3886 QPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQ 3945
Q K+ Q L++LQ +Q QQ +++Q Q + +Q+ L QQQLQ +Q QQLQQQ
Sbjct: 3248 QEKIMVQK--KLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQL-EQIQQLQQQLH 3304
Query: 3946 QQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKP 4005
QQL++Q+ + Q Q + +L L Q + A
Sbjct: 3305 QQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTASAVVA 3364
Query: 4006 LQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPST 4043
++ S G T+ G Q P + S +E P T
Sbjct: 3365 IEIPQSQGWY--TVQSDGVTQYIAPPGILSTVSEIPLT 3400
Score = 53.9 bits (128), Expect = 4e-06
Identities = 80/293 (27%), Positives = 110/293 (37%), Gaps = 33/293 (11%)
Query: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
P P P S + P R S L + ++ PPP PPP P PPP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP----PPPPPPPPPPPP---- 2423
Query: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE--EPQLCPRSEGPHLSPR 746
PPP PTSP P P + ++ S +PL E RS G ++ R
Sbjct: 2424 --PPPLPPPTSPKP---TILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT-R 2477
Query: 747 PEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP-HLSPQPEELH 805
P P +P P P+P +P + P P L + P + P+P L
Sbjct: 2478 ICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLS 2537
Query: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
L T L+ V P P S LSP S + SPR S L + +
Sbjct: 2538 L---TSSMTLNLVTSADYKLPSP-TSPLSPHSNKS--SPR-----FSKSLTETYVVITLP 2586
Query: 866 KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS 918
P P A + + + P G PS + EP S PP++ + E+P+S
Sbjct: 2587 SEPGTPTDSSASQAITSW-PLGSPSKDLVSVEPVFSV--VPPVTAV--EIPIS 2634
Score = 52.8 bits (125), Expect = 1e-05
Identities = 166/813 (20%), Positives = 258/813 (31%), Gaps = 125/813 (15%)
Query: 3723 LQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQ---QGPGV-----------QTNQA 3768
LQQQ + K Q + QQ ++ QQ ++ Q PG QT+ A
Sbjct: 211 LQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA 270
Query: 3769 LGPKPQGLMPPSSHQGLLVQQLSPQPP---------QGPQGMLGPAQVAVLQQQHPGALG 3819
P + P + Q +V+ S +P Q P PAQ ++ PG
Sbjct: 271 KLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAK 330
Query: 3820 PQG-------PHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAG 3872
P P Q T + P + +G AQQ ++ +Q
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA 390
Query: 3873 LSH---LQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQ--------LQQQQQQQLQ 3921
L+ + ++ G K Q +G+ + L QQ LQ + +QQ ++
Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP 450
Query: 3922 QQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981
QQ + QQ + Q + QQ + QQ + QQ G
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Query: 3982 RTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGP 4041
P + QQ PG P Q PG+ P+ ++ + P+
Sbjct: 511 PQQPGPAKPSPQQ----PGSTKPPSQQ---PGSAKPS----AQQPSPAKPSAQQSTKPVS 559
Query: 4042 STHQGGPLAIGTTPESMATEPGEVKPS----LSGDSQLLLVQPQP--------------- 4082
T G PL T S P + P L ++LLL P+
Sbjct: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619
Query: 4083 ----QPQPSSLQLQPPLRLPGQQQQQVSL-LHTAGGGSHGQLGSGSSSEASSVPHLLAQP 4137
P P +++ L L Q ++ + L +L + + S+V QP
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP 679
Query: 4138 SVSLGDQPGSMTQNLLGPQQPMLERPMQNNT----GPQPPKPGPVLQSGQGLPGVGIMPT 4193
+ + + Q+L +P P+ P P P P+
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPS 739
Query: 4194 VG--QLRAQLQGVLAKNPQL----RHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPG 4247
V Q +A + K P++ L + + ++Q + TPP +
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDS 799
Query: 4248 TQTSPLQGLLGCQPQLGGFP--GPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPV 4305
+ S FP G + P A PRP ++ + PG S V
Sbjct: 800 AKPSQ------------SFPPTGEKVSPFDSK-AIPRPASDSKIISHPGPSSESKGQKQV 846
Query: 4306 HPTPPPSSPQE------PK-----RPSQLPSPSSQLPTEAQLPPTHPGTPKPQ------- 4347
P P++ PK P P+P PT Q PT +PKPQ
Sbjct: 847 DPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFS 906
Query: 4348 ---GPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAET--QKPEQSSLVPG-HLDQ 4401
G + P + + + LF G + NL T Q S PG + Q
Sbjct: 907 LNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ 966
Query: 4402 VNGQVVPEASQLSIKQEPREEPCALGAQSVKRE 4434
P SQ K + P + VK+E
Sbjct: 967 APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKE 999
Score = 47.8 bits (112), Expect = 3e-04
Identities = 71/274 (25%), Positives = 94/274 (34%), Gaps = 41/274 (14%)
Query: 2350 QEPPPAQALAPSP-----PSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLP 2404
QE P +Q + SP P+ P F S D AQPP P P PPPP PP P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP------PPPPPP 2422
Query: 2405 SDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFA 2464
P P SP+ + LT SPVT D + + R
Sbjct: 2423 PPPPLPPPTSPKPTILPKKKLT---------VASPVTTATPLFDAVTTLETTAVLRSNGL 2473
Query: 2465 PLHK----PPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVR 2520
P+ + P P PP+ + L T P+ P P + + Q P +
Sbjct: 2474 PVTRICTTAPPPVPPKPSSIPSGLVFTHRPE---PSKPPIAPKPVIPQLPTTTQKPTDIH 2530
Query: 2521 SPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNY 2580
TG + + + V K P P L P +S P K + Y
Sbjct: 2531 PKPTGLSLTSSMTLNL-----VTSADYKLPSPTSPLSPHSNKSS-----PRFSKSLTETY 2580
Query: 2581 TVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPS 2614
V T PS P P+ S ++ PL PS
Sbjct: 2581 VVIT---LPS-EPGTPTDSSASQAITSWPLGSPS 2610
Score = 45.8 bits (107), Expect = 0.001
Identities = 115/513 (22%), Positives = 169/513 (32%), Gaps = 52/513 (10%)
Query: 498 PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPP 557
P ES S PP +P S + + S P L++ + E + FE+S
Sbjct: 2169 PSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDS----- 2223
Query: 558 PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPL 617
EE+ +S S + P E S +P A + + S P
Sbjct: 2224 -EEISSSTYFPGSIIDYPEEISVSLD--RTAPPDGRASADHIVISLSDMASSIIESVVPK 2280
Query: 618 SPPPEASRLSPP---PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
P A +S E P+ +E+ EV L L +S LS
Sbjct: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEV--LEAYRDKKELEAERTKSSLS-- 2336
Query: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734
E+ PP + P E T+ S + E LP + LP +P+
Sbjct: 2337 --ETVFDHPPSSVIALPMKEQLSTTY--FTSGETFGQEKPASQLPSGSPSVSSLPAKPRP 2392
Query: 735 CPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794
RS +S +P P P P P P P P +P + + SP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA 2452
Query: 795 PHLSPQPEELHLSPQTEEPHL----------SPVPEEPCLSPQPEESHLSPQSEEPCLSP 844
L L + L PVP +P P P+ +P ++P
Sbjct: 2453 TPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAP 2512
Query: 845 RPEESHLSPELEKP-PLSPRP-----------EKPPEEPGQCPAPEELPLFPPPGE--PS 890
+P L +KP + P+P + P+P PL P + P
Sbjct: 2513 KPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTS-PLSPHSNKSSPR 2571
Query: 891 LSPLLGEPAL-----SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPP--DPLPPPLSPII 943
S L E + SEPG P S + + P G PS + P +PP + I
Sbjct: 2572 FSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEI 2631
Query: 944 TAAAPPALSPLGELEYPFGAKGDSDPESPLAAP 976
++ G L+ F A + P S AAP
Sbjct: 2632 PISSEQTFYISGALQ-TFSATPVTAPSSFQAAP 2663
Score = 45.4 bits (106), Expect = 0.002
Identities = 51/205 (24%), Positives = 71/205 (34%), Gaps = 21/205 (10%)
Query: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS 477
P G V P P L + P PPP P PPP PPP P S
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP----PPPPLPPPTS 2432
Query: 478 PLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET--- 534
P P L + SP++ + P + LE + + P + T
Sbjct: 2433 PKPTILPKKKLTVASPVT--------TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPP 2484
Query: 535 PLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPP 594
P+ P P + P F P P + P +P P +L P + P P+ + +S
Sbjct: 2485 PVPPKPSSIPSGLVFTH---RPEPSKPPIAPKPVIPQL-PTTTQKPTDIHPKPTGLS--L 2538
Query: 595 EASRLFPPFEESPLSPPPEESPLSP 619
+S + P SPLSP
Sbjct: 2539 TSSMTLNLVTSADYKLPSPTSPLSP 2563
Score = 42.4 bits (98), Expect = 0.013
Identities = 68/317 (21%), Positives = 109/317 (34%), Gaps = 68/317 (21%)
Query: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206
+G G + P P V + PF + + + + P PP PP P P P
Sbjct: 2363 SGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP 2422
Query: 2207 AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG 2266
PP+ PP P++P P + P+ L V
Sbjct: 2423 PPPPL------------------PP------PTSPKPTILPK----KKLTV--------- 2445
Query: 2267 KASEPLLSPPPFGESRKALE---------VKKEELGASSPSYGPPNLGFVDSPSSGTHLG 2317
+ P+ + P ++ LE + + ++P PP + S TH
Sbjct: 2446 --ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTH-- 2501
Query: 2318 GLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE-PPPAQALAPSPPSHPDIFRPGSYTD 2376
P+ K P+ P+ V PQ P +P + P L+ + ++ Y
Sbjct: 2502 -----RPEPSKPPIAPK--PVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKL 2554
Query: 2377 PYAQPPLTPRPQPPPPESCCALPPR----SLPSDPFSRVPASPQSQSSSQSPLTPRPLSA 2432
P PL+P P +L +LPS+ P +P S+SQ+ +T PL +
Sbjct: 2555 PSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSE-----PGTPTDSSASQA-ITSWPLGS 2608
Query: 2433 EAFCPSPVTPRFQSPDP 2449
+ V P F P
Sbjct: 2609 PSKDLVSVEPVFSVVPP 2625
Score = 40.8 bits (94), Expect = 0.038
Identities = 68/279 (24%), Positives = 97/279 (34%), Gaps = 39/279 (13%)
Query: 835 PQSEEPCLSP-------RPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPG 887
P S+ P SP +P S L+ P P PP P P P P PPP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 888 EPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAA 947
P +L + L+ SP+ PL + + ++ + L P++ I T A
Sbjct: 2432 SPK-PTILPKKKLT-----VASPVTTATPLFDAVTTLETTAVLRSNGL--PVTRICTTAP 2483
Query: 948 PPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007
PP P P G PE S PP A P+PV P +
Sbjct: 2484 PPV--PPKPSSIPSGLVFTHRPEP-----------SKPPIA----PKPVIPQL------- 2519
Query: 1008 PVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDE 1067
P P + P P S +L S + P PLS S S +++
Sbjct: 2520 PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTET 2579
Query: 1068 AELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAP 1106
+ + +E + + A + + PL SP DL P
Sbjct: 2580 YVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEP 2618
Score = 40.0 bits (92), Expect = 0.064
Identities = 31/91 (34%), Positives = 40/91 (43%), Gaps = 15/91 (16%)
Query: 4881 QESPAPEPPTQHSYTYNVSNLDVR----------QLSAPPPEEPSPPPSPLAPSPASPPT 4930
QE PA + P S + +VS+L + +SA PP P PPP P P P PP
Sbjct: 2369 QEKPASQLP---SGSPSVSSLPAKPRPFFRSSSLDISAQPP--PPPPPPPPPPPPPPPPP 2423
Query: 4931 EPLVELPTEPLAEPPVPSPLPLASSPESARP 4961
P + PT P L +AS +A P
Sbjct: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 39.7 bits (91), Expect = 0.084
Identities = 48/184 (26%), Positives = 74/184 (40%), Gaps = 25/184 (13%)
Query: 520 LSPPEESPPSPAL------ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEAS--- 570
+S PE++ +L ++ P S SPP ++ P P E+ S A
Sbjct: 3553 ISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKK--RPTPLEIGYSSHLRADSTV 3610
Query: 571 RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE------SP---LSPPPEESPLSPPP 621
+L+P P +SP SP+SP F P+E+ SP L P + P + P
Sbjct: 3611 QLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPK 3670
Query: 622 EASRLSPPPED-SPMSPPPEESPMSP----PPEVSRLSPLPVVSRLSPPPEESPLSPPPE 676
A + D P+SP +ES +P ++ S S + + +PPPE
Sbjct: 3671 TAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPE 3730
Query: 677 ESPT 680
E T
Sbjct: 3731 EIST 3734
Score = 39.3 bits (90), Expect = 0.11
Identities = 40/132 (30%), Positives = 53/132 (40%), Gaps = 19/132 (14%)
Query: 446 ESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP 505
+S P S TSPP + R P P E+ S A + P SP SP+SP
Sbjct: 3572 DSDTQSPQYLSATSPPKDKKR--PTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP 3629
Query: 506 PPESSPFSPLE------ESPLSPPEESPPSPALETPLSPPPEASPLSPPF------EESP 553
SP LE E PL P++ P L ++ P ASP + + P
Sbjct: 3630 ---LSPGKALESAFVPYEKPL--PDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684
Query: 554 LSPPPEELPTSP 565
LSP +E +P
Sbjct: 3685 LSPTADESSRAP 3696
Score = 38.5 bits (88), Expect = 0.19
Identities = 81/346 (23%), Positives = 123/346 (35%), Gaps = 67/346 (19%)
Query: 4617 SNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDL 4676
S P +S+PP+ PS+ + + T +S + +LD
Sbjct: 2167 SEPSESATSVPPSDTPSLTSSVSSVCTTDS---------------------SSPITTLDS 2205
Query: 4677 LAALPTPPHNQTEDVRMESDEDSDS---PDSIVPASSPESI-LGEEAPRFPHLGSGRW-- 4730
+ + T P + +S+E S S P SI+ S+ L AP +
Sbjct: 2206 ITTVYTEPVDMITKFE-DSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVI 2264
Query: 4731 EQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSA 4790
D A S + ++P+ PV DT + L + K PV +K G+ + + + +
Sbjct: 2265 SLSDMASSIIESVVPKPEGPV-ADTV---STDLLISEKDPVKKAKKETGNGIILEVLEAY 2320
Query: 4791 AAAKNLNGVMV--AVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGK 4848
K L +++E + P+S + P + T GE G L
Sbjct: 2321 RDKKELEAERTKSSLSETVFDHPPSSV-IALPMKEQLSTTYFTSGETFGQEKPASQLPSG 2379
Query: 4849 SPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSA 4908
SP + A + S LDI + + P P PP
Sbjct: 2380 SPS-----VSSLPAKPRPFFRSSSLDISA----QPPPPPPP------------------- 2411
Query: 4909 PPPEEPSPPPSPLAPSPASPPTEPL-VELPTEPL-AEPPVPSPLPL 4952
PPP P PPP P P P PPT P LP + L PV + PL
Sbjct: 2412 PPPPPPPPPPPP--PPPLPPPTSPKPTILPKKKLTVASPVTTATPL 2455
Score = 37.4 bits (85), Expect = 0.42
Identities = 52/213 (24%), Positives = 74/213 (34%), Gaps = 12/213 (5%)
Query: 460 PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP 519
P E L+ PE+ +LH S +P + P S L +SSP ES
Sbjct: 1697 PELEMESLTDSPEDRSRGEGSSSLHAS---SFTPGTSPTSVSSLDEDSDSSPSHKKGESK 1753
Query: 520 LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579
P L + E L E E+ +S+ S ++
Sbjct: 1754 QQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDE 1813
Query: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP 639
+ E P +PP S P E++ SP E + E R S + P
Sbjct: 1814 LRAQRRRERPKTPPSNLS----PIEDA--SPTEELRQAAEMEELHRSSCSEYSPSIESDP 1867
Query: 640 EESPMSPPP--EVSRLSPLP-VVSRLSPPPEES 669
E +SP EV ++ LP VS SP E+S
Sbjct: 1868 EGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQS 1900
Score = 36.2 bits (82), Expect = 0.93
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 4548 SEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQL-RGAFGSGALPTGPDY 4606
SE + + LP+ E T F+ FG P SQL G+ +LP P
Sbjct: 2336 SETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPA---SQLPSGSPSVSSLPAKPRP 2392
Query: 4607 YSQLLTKNNLSNPPTPPSSLPPTPPP 4632
+ + + + + PP PP PP PPP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPP 2418
Score = 36.2 bits (82), Expect = 0.93
Identities = 49/195 (25%), Positives = 70/195 (35%), Gaps = 17/195 (8%)
Query: 2107 PPQPGALGSPPPAAAPTIF------IGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELF 2160
PP P PP + PTI + SP T A A L+ A +
Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRIC 2479
Query: 2161 LKLPPQVPAQVPSQDPFGLAPAYPLEP-RFPTAP-PTYPPYPSPTGAPA----QPPMLGA 2214
PP VP + PS P GL + EP + P AP P P P+ T P +P L
Sbjct: 2480 TTAPPPVPPK-PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSL 2538
Query: 2215 SSRPGAG--QPGEFHTTPPGTP--RHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASE 2270
+S ++ P +P H + F K + + +P PG ++
Sbjct: 2539 TSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSAS 2598
Query: 2271 PLLSPPPFGESRKAL 2285
++ P G K L
Sbjct: 2599 QAITSWPLGSPSKDL 2613
Score = 35.8 bits (81), Expect = 1.2
Identities = 25/68 (36%), Positives = 26/68 (38%), Gaps = 10/68 (14%)
Query: 4275 QELGAGPRPQGPPR---LPAPPGALSTGPVLG-------PVHPTPPPSSPQEPKRPSQLP 4324
QE A P G P LPA P L P P PPP P P P LP
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 4325 SPSSQLPT 4332
P+S PT
Sbjct: 2429 PPTSPKPT 2436
Score = 35.4 bits (80), Expect = 1.6
Identities = 35/118 (29%), Positives = 48/118 (40%), Gaps = 21/118 (17%)
Query: 4276 ELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQE---PKRPSQLPSP------ 4326
++ A P P PP P PP P P P PPP+SP+ PK+ + SP
Sbjct: 2400 DISAQPPPPPPPPPPPPPP-----PPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Query: 4327 ----SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
+ L T A L G P + T PPP P++ + +F+ P PP
Sbjct: 2455 LFDAVTTLETTAVLRSN--GLPVTRICTTAPPPVPPKPSSIP-SGLVFTHRPEPSKPP 2509
Score = 34.7 bits (78), Expect = 2.7
Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 6/83 (7%)
Query: 4297 STGPVLGPVHPTP--PPSSPQEPKRPSQLPSP---SSQLPTEAQLPPTHPGTPKPQGPTL 4351
++G G P P SP P++ P P SS L AQ PP P P P P
Sbjct: 2362 TSGETFGQEKPASQLPSGSPSVSSLPAK-PRPFFRSSSLDISAQPPPPPPPPPPPPPPPP 2420
Query: 4352 EPPPGRVSPAAAQLADTLFSKGL 4374
PPP + P + L K L
Sbjct: 2421 PPPPPPLPPPTSPKPTILPKKKL 2443
Score = 33.9 bits (76), Expect = 4.6
Identities = 51/184 (27%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 695 DSPTSPPPEDSPASPPPEDSLMSLPLE--ESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL 752
DS T P S A+ PP+D PLE S L QL P SP P+ P +
Sbjct: 3572 DSDTQSPQYLS-ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAP-------SP-PKSPKV 3622
Query: 753 SPRPEEPHLSP-----QAEEPHLSPQPEEPCLCAVPEEPHLSPQAE-GPHLSPQPEELHL 806
P P LSP A P+ P P++ +SPQ P ++ P
Sbjct: 3623 LYSPISP-LSPGKALESAFVPYEKPLPDD-----------ISPQKVLHPDMAKVPPA--- 3667
Query: 807 SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEK 866
SP+T + + + LSP +ES +P + + ++ S +K P
Sbjct: 3668 SPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNP 3727
Query: 867 PPEE 870
PPEE
Sbjct: 3728 PPEE 3731
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 158 bits (399), Expect = 2e-37
Identities = 242/997 (24%), Positives = 371/997 (37%), Gaps = 173/997 (17%)
Query: 358 IRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAK 417
+ SV + P S E T + + QG+P+G +Q + P P+ +
Sbjct: 166 VSSVVNKFNPF-DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQG 224
Query: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP---PEASRLSPPPEEL 474
P G+ +Q + ++ +++ PE+ PP P P P+ P +
Sbjct: 225 P-GRDPLQQDGTPKSISSQQ------PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRD 277
Query: 475 PASPLPEALHLSR-----PLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPS 529
+ P + + R P SP PP ++ PP P E+S P
Sbjct: 278 ASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQP----------GHEKSQPG 327
Query: 530 PALETPLSPPPEASPLSPPFEESP-LSPPPEELPTSPPPEASRLSP--PP-----EESPM 581
PA PP + S L+ P + P PP + P + P A L P PP E P
Sbjct: 328 PA-----KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS 382
Query: 582 SPPPEESPMSPPPEASRLFPPFEESPLSPPPEE----SPLSPPP--EASRLSPPPEDSPM 635
S P ++ PP + P + P PP ++ PL+ P ++ +P P +P+
Sbjct: 383 SEQPGPKALAQPPGVGKT-PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 636 SPP-PEESP--MSPPPEVSRLSPLPVVSRLSPPPE-ESPLSPPPEE-SPTSPPPEASRLS 690
P P + P + P + S P PP + P PPP++ P PPP+ +
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPT----KPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 691 PPPEDSP--TSPPPED-SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747
PP P T PPP+ PA P P+ + P + P P Q P S +P
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 748 EEPHLSPRP-EEPHLSPQAEEPHLSPQPEEPC--------LCAVPEEPHLSPQAE----- 793
S +P + P +SP A++P P+ C L VPE+ + + E
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617
Query: 794 --------GPHLSPQPEELHLSPQTEEP---HLSPVPEEPCLSPQPEESHLSPQSEEPCL 842
PHL+ E L L+ Q + L+PVP P P+ + + ++ S
Sbjct: 618 CSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLKTAPVTTTSAVSKS 675
Query: 843 SPRPEESHLSPELEKPP-----LSPRPEKPP-------------EEPGQCPAPEELPLFP 884
SP+P+++ SP+ + P +P P+KPP + Q P + L
Sbjct: 676 SPQPQQT--SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 885 PPGEPSLSPLLGEPALSE--PGEPPLSPLPEELPLSPSGE-----PSLSPQLMPPDPLPP 937
PP EPS+ + +++ P +P + +L S S PS Q + P
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 938 PLSPIITAAAPPALS--PLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEP 995
PL T +A P+ S P GE PF +K P S + I+ P P + +
Sbjct: 794 PLK---TDSAKPSQSFPPTGEKVSPFDSKAIPRPASD--SKIIS---HPGPSSESKGQKQ 845
Query: 996 VPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSP- 1054
V P+ P SP P P+ P+ SP P +VP+P
Sbjct: 846 VDPVQKKEEPKKAQTKMSP------KPDAKPM------PKGSPTPPGPRPTAGQTVPTPQ 893
Query: 1055 LSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT-----SPLPSPMGDLSCPAPSPA 1109
SP + L + S+P P + + + S +L A P
Sbjct: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
Query: 1110 PALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVY 1169
P G AP+ AP SQP Q P + AP P +
Sbjct: 954 PHSQSGPG-----APMKQAPAP-SQPPTSQGPPKSTGQ-------------APPAPAKSI 994
Query: 1170 PECKQTAGQGSPCEEQEEPRAPVAPT---PPTLIKSDIVNEISNLSQGDASASFPGSEPL 1226
P K+T +P E+ EP+A APT T K + + +L+ A P L
Sbjct: 995 PVKKETK---APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLP--TKL 1049
Query: 1227 LGSPDPEGGGSL-SMELGVSTDVSPARDEGSLRLCTD 1262
SP PE L EL + ++D + CT+
Sbjct: 1050 EKSPKPESTCPLCKTELNIG-----SKDPPNFNTCTE 1081
Score = 115 bits (287), Expect = 2e-24
Identities = 236/1108 (21%), Positives = 363/1108 (32%), Gaps = 193/1108 (17%)
Query: 442 PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASP--------------------LPE 481
P ESP +E +S PP+ S P P PA P P
Sbjct: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGR-PAQPGLSKSRTTDTFRSEQKLPGRSPS 131
Query: 482 ALHLSRPLEESPLSPPPEESPL--------------SPPPESSPFSPLEESPLSPPEESP 527
+ L + L + S + S + +PF + +S S E +
Sbjct: 132 TISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTK 191
Query: 528 PSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP------EASRLSPPPEESPM 581
++ P + PP ++ P P P++ P S S PE+
Sbjct: 192 KQKVVQKEQGKP--EGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKS 249
Query: 582 SPPPEESPMSPP---PEASRLFPPFEESPLSP--------------PPEESPLSPPPEAS 624
PP P+ P P+ P + P P SP PP +
Sbjct: 250 QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
Query: 625 RLSPPPEDSPMSPPPEESPMSPPPEVSRLS------PLPVVSRLSPP----PEESPLSP- 673
PP P + P PP + S L+ P V + PP P PL P
Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA 369
Query: 674 -PP-----EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP 727
PP E P+S P L+ PP T P + PA PP + PL + P L
Sbjct: 370 KPPAQQTGSEKPSSEQPGPKALAQPPGVGKT-PAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428
Query: 728 LPEE---PQLCP-RSEGPHLSP-------RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776
P + P P + GP P + P L A+ P P P +
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 777 PCLCAVPEEP-HLSPQAEGPHLSPQPEEL--HLSPQTEEPHLSPVPEEPCLSPQPEESHL 833
P P++P P ++ P + P + P ++P + P + S +P
Sbjct: 489 P----PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544
Query: 834 SPQSEEPCLSPRP-EESHLSPELEKPPLSPRPEKPPEEP------GQCPAPEELPLFPPP 886
SP S +P ++ L+ P +SP ++PP + C E L P
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEK 604
Query: 887 GEPSLSPLLGEPALSEPG---EPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPP---LS 940
+ S G P L+ + E L L+ + +L L P P P +
Sbjct: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA 664
Query: 941 PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMI 1000
P+ T +A SP + P K D+ P+ L+ PEP P
Sbjct: 665 PVTTTSAVSKSSPQPQQTSP---KKDAAPKQDLSKA----------------PEPKKP-- 703
Query: 1001 LPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGK 1060
PP P SP PP+ L + + + S PS+ P++ P P K
Sbjct: 704 -PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSE--QDKAPVADDKPKQP--K 758
Query: 1061 VVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGE 1120
+V + + T K P + P D + P+ S F GE
Sbjct: 759 MVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQS-------FPPTGE 811
Query: 1121 DTAPLD--GIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQ 1178
+P D I P S + PG +SE KG V P++ E K+ +
Sbjct: 812 KVSPFDSKAIPRPASDSKIISHPGP-SSESKGQ---------KQVDPVQKKEEPKKAQTK 861
Query: 1179 GSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDP-EGGGS 1237
SP + +P +PTPP + A + P + SP P E
Sbjct: 862 MSP-KPDAKPMPKGSPTPPG-------------PRPTAGQTVPTPQQ---SPKPQEQSRR 904
Query: 1238 LSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPAR 1297
S+ LG TD ++ T L S+ A IS G+ G S
Sbjct: 905 FSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS---TAGQPGPHSQSGPG 961
Query: 1298 SRIKQGRSSSFP----GRRRPRGGAHGG-----------RGRGRARLKSTASSIETLVVA 1342
+ +KQ + S P G + G A + +L+ A T+
Sbjct: 962 APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT 1021
Query: 1343 DIDSSPSKEEEEEDDDTMQNTVVLFSNTDKFVLMQDMCVVCG---SFGRGAEGHLLACSQ 1399
+ + P ++ + VL + +K + C +C + G + C++
Sbjct: 1022 ETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTE 1081
Query: 1400 CSQCYHPYCVNSKITKVMLLKGWRCVEC 1427
C C + + ++ W C+ C
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNC 1109
Score = 104 bits (259), Expect = 3e-21
Identities = 186/786 (23%), Positives = 263/786 (33%), Gaps = 134/786 (17%)
Query: 518 SPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
S LS E + + P + P P ESP +EL +S PP+ S
Sbjct: 46 SQLSEEERRQIAAVMSRAQGLPKGSVP--PAAAESPSMHRKQELDSSHPPKQSG------ 97
Query: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637
PP P P SR F P S +S SR E
Sbjct: 98 ----RPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMM 153
Query: 638 PPEESPMSPPPEVS----RLSPLPVVSRLSPPPEESP----------------LSPPPEE 677
P S ++ VS + +P ++S EE+ + PP ++
Sbjct: 154 PGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ 213
Query: 678 SPTSPPPE---------------ASRLSPPPEDSPTSPPPEDSPASPP---PEDSLMSLP 719
P P P+ S S PE + PP P P P+ LP
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP 273
Query: 720 LEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL-SPRPEEPHLSPQAEEPHLSPQPEEPC 778
L+ P ++ + P P +P + P P +P P + H QP
Sbjct: 274 LQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP---PAQQPGHEKSQPG--- 327
Query: 779 LCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE 838
P +P P L+ QP + P + P + P +P L P + + +
Sbjct: 328 ----PAKPPAQPSGLTKPLAQQPGT--VKPPVQPPGTTKPPAQP-LGPAKPPAQQTGSEK 380
Query: 839 EPCLSPRPEESHLSPELEKPPL-SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897
P P+ P + K P P P KPP + Q P+ L P P+ +P +
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ--QVGTPKPLAQQPGLQSPAKAPGPTK 438
Query: 898 PALSEPGEPPLSPLPEELPLSPSGE---PSLSPQLMPPDPLPPPLSPIITAAAPPALSPL 954
+ +PG P P + P S + P+ P +P PPP P A PP P
Sbjct: 439 TPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP--GPAKPPPQQP- 494
Query: 955 GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASP 1014
G + P G + P P +P P T P P PS P PA P
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSPQQP----GSTKPPSQQPGSAKPSAQQP-SPAKP 549
Query: 1015 ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEME 1074
+ P L P PS PP+ L P + P+ + E LH E
Sbjct: 550 SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL--PKTICPLCN----TTELLLHVPE 603
Query: 1075 TEKVSE-PECPALEPSATSPLPSPM-------------------GDLSCPAPSPAPALDD 1114
+ EC S P+P GDL+ SP P L
Sbjct: 604 KANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL-- 661
Query: 1115 FSGLGEDTAPLDGIDAPG-SQPEPGQTPG----------SLASELKGSPVLLDPEEL--A 1161
TAP+ A S P+P QT S A E K P L+ L +
Sbjct: 662 ------KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715
Query: 1162 PVTPMEVYPECKQTAGQGSPCE---EQEEPRAPVA---PTPPTLIK--SDIVNEISNLSQ 1213
P + PE + P E E+ +APVA P P ++K +D+V+ S ++
Sbjct: 716 PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK 775
Query: 1214 GDASAS 1219
D +S
Sbjct: 776 PDIPSS 781
Score = 92.4 bits (228), Expect = 1e-17
Identities = 178/816 (21%), Positives = 269/816 (32%), Gaps = 181/816 (22%)
Query: 352 AQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPK-------------- 397
AQ + A+Q T S+ +P PT P A QG PK
Sbjct: 541 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH 600
Query: 398 -------------GGHVTSMQPKEPGP----------LQCEAKPLGKAGVQLEPQLEAPL 434
V S+ P P L C+ K + P P
Sbjct: 601 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660
Query: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEAS---RLSPPPEELPASPLPEALHLSRPLEE 491
+ P+ S SP P++ TSP +A+ LS PE PL + L
Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQ--TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLS--PPF 549
PP +S P P P P E+ ++ P P + P + +S + P
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Query: 550 EESPLSPPPEELPTSPPPEASRLSP----PPEESPMSPPPEESPMSPPPEASRLFPPFEE 605
S + EE T+PP + P PP +SP ++ P ++ + P
Sbjct: 779 PSSKVQSQAEE-KTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPS 837
Query: 606 SPLSPPPEESPL----SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSR 661
S + P+ P +++SP P+ PM P +P P P + P P +
Sbjct: 838 SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPM-PKGSPTPPGPRPTAGQTVPTP---Q 893
Query: 662 LSPPPEE---------SPLSPPPEESPTSP------------------------------ 682
SP P+E ++ P+ PT+P
Sbjct: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
Query: 683 ------PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736
P + +P P PTS P S PP + S+P+++ P E +L P
Sbjct: 954 PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA-KSIPVKKETKAPAAE--KLEP 1010
Query: 737 RSE-GPHLSPRPEEPHLSPRPEEPHLSPQAEEPHL------SPQPEEPC-LCAV------ 782
++E P + E P + L+ + ++ L SP+PE C LC
Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS 1070
Query: 783 PEEPHLSPQAE-------------GPHLSPQPEELHLSPQTEEP---------HLSPVPE 820
+ P+ + E PHL+ E L L+ QT+ + P P
Sbjct: 1071 KDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPS 1130
Query: 821 EPCLSPQPEESHLSPQSEEPCLSP-----RPEESHLSPELEKPPLSPRPEKPPEEPGQCP 875
P SP P + S S++ + P + +E + E EK L E+ +
Sbjct: 1131 GPKASPMPVPTESS--SQKTAVPPQVKLVKKQEQEVKTEAEKVIL--------EKVKETL 1180
Query: 876 APEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMP---- 931
+ E++P + L + S E PLPEE L P E S + P
Sbjct: 1181 SMEKIPPMVTTDQKQEESKLEKDKASALQEK--KPLPEEKKLIPEEEKIRSEEKKPLLEE 1238
Query: 932 --PDPLPPPLSPIITAAAPP-------------ALSPLGELEYPFGAKGDSDPESPLAAP 976
P P L P +AP A L P + P++ +
Sbjct: 1239 KKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGL 1298
Query: 977 ILETPISPPPEANCT----DPEPVPPMILPPSPGSP 1008
TP S P E + T +P PP P P
Sbjct: 1299 PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334
Score = 85.9 bits (211), Expect = 1e-15
Identities = 251/1123 (22%), Positives = 366/1123 (32%), Gaps = 204/1123 (18%)
Query: 1929 GLPLGNLPSSSPMDSYPGLCQSPFLDSRE--RGGFFSPEPGEPDSPWTGSGGTTPSTPTT 1986
GLP G++P ++ P + + LDS + P+PG P P TT + +
Sbjct: 65 GLPKGSVPPAAAES--PSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSE 122
Query: 1987 PTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSSRCKQIM 2046
G + S R + EE S++ P + +N S ++
Sbjct: 123 QKLPGRSPSTISLKESKSRTDLKEE--HKSSMMPGFLSEVNA----------LSAVSSVV 170
Query: 2047 KLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKV--GDIARKTDRPALHL 2104
+ P+ + + K QK + + K + + ++ +P
Sbjct: 171 NKFN--------PFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP---- 218
Query: 2105 RIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP 2164
IP Q G G P T S P + + G KP G P + KLP
Sbjct: 219 -IPKQQGP-GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD---HAKLP 273
Query: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGA---------------PAQP 2209
Q A P + ++P P+ P+ PP PT PA+P
Sbjct: 274 LQRDASRPQTKQADIVRGESVKPSLPS--PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP 331
Query: 2210 PMLGAS-SRPGAGQPGEFH--TTPPGT---------PRHQPSTPDPFLKPRCPSLDNLAV 2257
P + ++P A QPG PPGT P P+ KP A+
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL 391
Query: 2258 PESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGP-PNLGFVDSPSSGTHL 2316
+ PGVG A +P + PP + + ++ G SP+ P P V P G
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP-GLQSPAKAPGPTKTPVQQPGPG--- 447
Query: 2317 GGLELKTPDVFKAPLTPRASQVEPQSPGLGLR------PQEPPPAQALAPSPPS-HPDIF 2369
K P P A Q P P L PQ+P PA+ P S P
Sbjct: 448 -----KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 2370 RPGSYTDPYAQP-PLTPRPQ------PPPPESCCALPPRSLPS--DPFSRVPASPQSQSS 2420
+PGS P QP P P PQ PP + A P PS P ++ P SQ+
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 2421 SQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR--PQSRDPFAPLHKPPRPQPPEVA 2478
S PL P +S A +PPS+ P++ P + P +
Sbjct: 563 SGKPLQPPTVSPSA----------------KQPPSQGLPKTICPLCNTTELLLHVPEKAN 606
Query: 2479 FKAGSLAHTSL-GAGGF---------------PAALPAGPAGELHAKVPSGQPPNFVRSP 2522
F + T++ GF + G+L A VPS P +P
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDL-APVPSSPQPKLKTAP 665
Query: 2523 GT---GAFVGTPSPMRFTFPQAVGEPSLK-PPVPQPGLPPPHGINSHFGPGPTLGKPQST 2578
T +P P + T P+ P P+P PPP PTL
Sbjct: 666 VTTTSAVSKSSPQPQQ-TSPKKDAAPKQDLSKAPEPKKPPP------LVKQPTL------ 712
Query: 2579 NYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGI 2638
GSP + E+ LS PP P+ P Q
Sbjct: 713 -----------HGSP-SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ---- 756
Query: 2639 TSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRN 2698
K P T + SS + P P SQ E EK + Q
Sbjct: 757 ----PKMVKPTTDLVSSSSATTKPDI--PSSKVQSQAE-EKTTPPLKTDSAKPSQSFPPT 809
Query: 2699 TLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSG 2758
++ + + A+ P S S P S+GQ Q K P K
Sbjct: 810 ----GEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEE-----PKK--- 857
Query: 2759 PILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLW 2818
+ ++S P P A P M S G Q P P P Q+Q + +
Sbjct: 858 ---------AQTKMS-PKPDAKP--MPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRF 905
Query: 2819 QQQQATAATSMRFAMSARFPSTPGPELGRQALG---SPLAGISTRLPGPGEPVP----GP 2871
+ + + P+TP + + G S + S + G+P P GP
Sbjct: 906 SLNLGSITDAPKSQ-----PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 2872 AGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPP 2931
P + GP + GQ PP + PV ++ A E L A
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKS--TGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
Query: 2932 QK-PSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTEL 2973
++ + P + +S T + LPT LE +P S+ L
Sbjct: 1019 KRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
Score = 84.7 bits (208), Expect = 2e-15
Identities = 188/829 (22%), Positives = 280/829 (33%), Gaps = 146/829 (17%)
Query: 3954 QLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPG 4013
+ Q++ ++Q+ Q++Q + G++ P+ +QQ GPG PLQ +P
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQ---GPGRD--PLQQDGTPK 237
Query: 4014 ALGPTLLLTGKEQNTVDPAVSSEATEGPST-HQGGPLAIGT----TPESMATEPGEVKPS 4068
++ K Q T+ P T H PL T ++ VKPS
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297
Query: 4069 LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEAS 4128
L S+ + QP P +PP + PG ++ Q G SG + +
Sbjct: 298 LPSPSKPPIQQPTPG--------KPPAQQPGHEKSQ------PGPAKPPAQPSGLTKPLA 343
Query: 4129 SVPHLLAQPSVSLGDQPGSMTQ---NLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGL 4185
P + P QP T+ LGP +P ++ + P P + Q
Sbjct: 344 QQPGTVKPPV-----QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP---- 394
Query: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTP---P 4242
PGVG P AQ G P QQ L Q+ QS A P P
Sbjct: 395 PGVGKTP------AQQPGPAKP--------PTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 4243 YQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVL 4302
Q+PG P Q Q G QTGP + P P PP P PG P
Sbjct: 441 VQQPGPGKIPAQ-----QAGPGKTSAQQTGPTKPPSQLPGPAKPP--PQQPGPAKPPPQQ 493
Query: 4303 GPVHPTPPPSSPQEPKRPSQLPSP---SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVS 4359
P PP P K P Q P P S Q P + P PG+ KP +P P +
Sbjct: 494 -PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ--QPSPAK-- 548
Query: 4360 PAAAQLADTLFSKGLG-PWDPPDNLAETQKPEQSSLVPGHLDQVNGQV----VPEASQLS 4414
P+A Q + G G P PP ++P L N VPE + +
Sbjct: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 4415 IKQEPREEPCALGAQS-----------------VKREANGEPIGAPGTSNHLLLAGP--- 4454
E + C+L + +KR G+ P + L P
Sbjct: 609 TCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTT 668
Query: 4455 -----------------RSEAGHLLLQKLLRAKN----VQLSTGRGSEGLRAEINGHIDS 4493
+ A L K K V+ T GS +A+ DS
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728
Query: 4494 KLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLK 4553
K PS ++ A +PK V+ +D LVSS K D + ++
Sbjct: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTD-LVSSSSATTKPD---IPSSKVQ 784
Query: 4554 QLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTK 4613
+E + PL + + S F P G + F S A+P P S++++
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQS-FPPTG---------EKVSPFDSKAIPR-PASDSKIISH 833
Query: 4614 NNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKS 4673
S+ + P +K ++P + PK + + T
Sbjct: 834 PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT----- 888
Query: 4674 LDLLAALPTP-----PHNQTEDVRMESDEDSDSPDSIVPASSPESILGE 4717
+PTP P Q+ + +D+P S P + E++ G+
Sbjct: 889 ------VPTPQQSPKPQEQSRRFSLNLGSITDAPKS-QPTTPQETVTGK 930
Score = 72.8 bits (177), Expect = 9e-12
Identities = 288/1380 (20%), Positives = 441/1380 (31%), Gaps = 295/1380 (21%)
Query: 3856 QQQQQQQQHQQQGSMAGLSHLQQS----LMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQ 3911
QQQ + +QQG G LQQ +S K+ +QP G+ + +Q Q Q
Sbjct: 212 QQQPPKPIPKQQGP--GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 3912 LQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQ 3971
+ Q+ + Q Q ++ + + L + +QQ QQ ++ Q
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 3972 QQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDP 4031
+ Q L P QQ PG P+Q PG P G + P
Sbjct: 330 KPPA----QPSGLTKPLAQQ-------PGTVKPPVQ---PPGTTKPPAQPLGPAK----P 371
Query: 4032 AVSSEATEGPSTHQGGPLAIGTTP---ESMATEPGEVKPSLS--GDSQLLLVQP------ 4080
+E PS+ Q GP A+ P ++ A +PG KP G + L QP
Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA 431
Query: 4081 -QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSV 4139
P P + +Q P ++P QQ AG G +G + S +P P
Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQ---------AGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
Query: 4140 SLG------DQPGSMTQNLL-----------------GPQQPMLERPMQNNTG------- 4169
G QPGS PQQP +P G
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ 542
Query: 4170 -PQPPKPG------PVLQSGQGLP--------------GVGIMPTVGQLRAQLQGVLAKN 4208
P P KP PV Q+G G P G+ T+ L +L
Sbjct: 543 QPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL-CNTTELLLHV 601
Query: 4209 PQLRHLS------------------PQQQQQLQALLMQRQLQQSQA--VRQTPPYQEPGT 4248
P+ + + P + + L + Q++++ + P +P
Sbjct: 602 PEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661
Query: 4249 QTSPLQGLLGC-----QPQLGGFPGPQTGPLQELGAGPRPQGPPRL-------------- 4289
+T+P+ QPQ P P Q+L P P+ PP L
Sbjct: 662 KTAPVTTTSAVSKSSPQPQQTS-PKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA 720
Query: 4290 PAPPGALSTGPVLGPVHPTPP------PSSPQEPKRPSQLPS----------------PS 4327
PP A S P P+ P P + +PK+P + PS
Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Query: 4328 SQLPTEAQ---LPPTHPGTPKPQ---GPTLE----------PPPGRVSPAAAQLADTLFS 4371
S++ ++A+ PP + KP PT E P P S + + S
Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840
Query: 4372 KGLGPWDPPDNLAETQK--------------PEQSSLVPGHLDQVNGQVVPEASQLSIKQ 4417
KG DP E +K P+ S PG GQ VP Q S K
Sbjct: 841 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA-GQTVPTPQQ-SPKP 898
Query: 4418 EPREEPCALGAQSVKREANGEPIGAPGT----------------SNHLLLA---GPRSEA 4458
+ + +L S+ +P T SN + A GP S++
Sbjct: 899 QEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958
Query: 4459 GHLLLQKLLRA-------KNVQLSTGRGSEGLRAEINGHIDSKLAG---LEQKLQGTPSN 4508
G K A + STG+ I ++K LE K + P+
Sbjct: 959 GPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
Query: 4509 KEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPA 4568
K +KP K + A + KL K E+ K EL++ P
Sbjct: 1019 KRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP---KPESTCPLCKTELNIGSKDPPN 1075
Query: 4569 ITANFSLFAPFGSGCPVNGQSQLRGAFGSGAL--PTGPDYYSQLLTKNNLSNPPTPPSSL 4626
+ C N L L T QL + P+ P +
Sbjct: 1076 FNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKAS 1135
Query: 4627 P-PTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPH 4685
P P P S QK V P +L + + + L E S++ + + T
Sbjct: 1136 PMPVPTESSSQK--TAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 4686 NQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIP--- 4742
Q E+ ++E D+ S A + L EE P R E++ L P
Sbjct: 1194 KQ-EESKLEKDKAS--------ALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPE 1244
Query: 4743 ---LIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGV 4799
L+P A P+ + + L +V EK +G + + G+
Sbjct: 1245 DKKLLPEAKTSA-PEEQKHDLLKSQVQ-----IAEEKLEGRVAPKTVQEGKQPQTKMEGL 1298
Query: 4800 MVAVAELLSMKIPNSYEVL--FPESPARA---GTEPKKGEAEGPGGKEKGLEGKSP---- 4850
+ L + + + + P+ P A EP K + E K + P
Sbjct: 1299 PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQ 1358
Query: 4851 ---DTG--PDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQ 4905
DTG D + +P + DIL LK++S + E S D+ +
Sbjct: 1359 GLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPS-------SPSDLAK 1411
Query: 4906 LSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPS---PLPLASSPESARPK 4962
L + S LA + T+P P +P + S L + S E +
Sbjct: 1412 LESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIK-- 1469
Query: 4963 PRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRP 5022
E ++ R KK Q+ +D +E +EF++ + T P
Sbjct: 1470 -------ESQEERKDTFKK-------------DSQQDIPSSKDHKEKSEFVDDITTRREP 1509
Score = 65.5 bits (158), Expect = 1e-09
Identities = 109/486 (22%), Positives = 171/486 (35%), Gaps = 75/486 (15%)
Query: 4023 GKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLV---- 4078
G + +V PA A E PS H+ L P+ P +P+ G S+
Sbjct: 65 GLPKGSVPPA----AAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR 120
Query: 4079 --QPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQ 4136
Q P PS++ L+ +++ S + L + SS P L
Sbjct: 121 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180
Query: 4137 PSVSLGDQ---PGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQ-------SGQGLP 4186
S + ++ + Q G + +++ P+Q QPPKP P Q G P
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ----QPPKPIPKQQGPGRDPLQQDGTP 236
Query: 4187 GVGIMPTVGQLRAQLQGV------LAKNPQLRHLS-PQQQQQLQALLMQRQLQQSQAVRQ 4239
++++Q G + PQ H P Q+ + Q + + ++V+
Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP 296
Query: 4240 T------PPYQEPGTQTSPLQ--GLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPA 4291
+ PP Q+P P Q G QP P +G + L P PP
Sbjct: 297 SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP--VQ 354
Query: 4292 PPGALSTGPVLGPVHPTPPPSSPQEPKRP-SQLPSPS------------SQLPTEAQLPP 4338
PPG +T P P+ P PP+ ++P S+ P P +Q P A+ P
Sbjct: 355 PPG--TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412
Query: 4339 THPGTPKP-----------------QGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPD 4381
GTPKP + P +P PG++ PA ++ GP PP
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI-PAQQAGPGKTSAQQTGPTKPPS 471
Query: 4382 NLAETQKPEQSSLVPGH-LDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPI 4440
L KP P Q G P + Q + P ++P + + P
Sbjct: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 4441 GAPGTS 4446
PG++
Sbjct: 532 QQPGSA 537
Score = 59.7 bits (143), Expect = 8e-08
Identities = 76/268 (28%), Positives = 95/268 (35%), Gaps = 32/268 (11%)
Query: 454 EESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFS 513
+E P S P S P LPA P P S + P PPP P PPP P
Sbjct: 2369 QEKPASQLPSGS---PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Query: 514 PLEESPLSPPEESPPSPALETPLSPPPEASPL--------SPPFEESPLSPPPEELPTSP 565
PL P SP P L T SP A+PL + S P T+P
Sbjct: 2426 PL-PPPTSPKPTILPKKKL-TVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
Query: 566 PPEASRLSPPPEESPMS------PPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP 619
PP + P P P P P + P++P P +L P + P P+ + LS
Sbjct: 2484 PP----VPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL-PTTTQKPTDIHPKPTGLSL 2538
Query: 620 PPEASRLSPPPED----SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
+ D SP SP S S P L+ VV L P +P
Sbjct: 2539 TSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITL-PSEPGTPTDSSA 2597
Query: 676 EESPTSPP---PEASRLSPPPEDSPTSP 700
++ TS P P +S P S P
Sbjct: 2598 SQAITSWPLGSPSKDLVSVEPVFSVVPP 2625
Score = 58.5 bits (140), Expect = 2e-07
Identities = 212/1083 (19%), Positives = 361/1083 (33%), Gaps = 169/1083 (15%)
Query: 2611 RPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMS 2670
+PP +P G P G + P + + P PGT P +
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP-------------PGTGKP-IQ 259
Query: 2671 GLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFE 2730
G +QT Q +L +QR+ R + + A G P PS P +
Sbjct: 260 GPTQTP---QTDHAKL-------PLQRDASRPQTKQADIVRGESVKPSL--PSPSKPPIQ 307
Query: 2731 QLSRGQTPFAGTQDKSSLVG--LPPSKLSG--------------PILGPGSF-PSDDRLS 2773
Q + G+ P + S G PP++ SG P+ PG+ P L
Sbjct: 308 QPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG 367
Query: 2774 RPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQ------QQQLWQQQQATAAT 2827
PPA + + S + G + P G P QQ QQ+ +
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKAL--AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP 425
Query: 2828 SMRFAMSARFPS-TPGPELGRQALGSPLAG---ISTRLPGPGEP---VPGPAGPAQFIEL 2880
++ A P+ TP + G + + AG S + GP +P +PGPA P
Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP------ 479
Query: 2881 RHNVQKGLGPGGTPFPGQGPPQRP-RFYPVSEDPHRLAPEGLRGLAVSGLPPQKPS-APP 2938
P P P + PPQ+P P S+ P P PPQ+P A P
Sbjct: 480 ---------PPQQPGPAKPPPQQPGSAKPPSQQPGSTKP-----------PPQQPGPAKP 519
Query: 2939 APELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFD 2998
+P+ S P G P+ + PS+ + P++ P + P +
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ--STKPVSQTGSGKPLQPPTVSPSAK 577
Query: 2999 AHKALEDDEELAHLGLGVDVAKGDDE---LGTLENLETN---------DPHLDDL----- 3041
+ + + L ++ E T +T +PHL ++
Sbjct: 578 QPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLC 637
Query: 3042 --------LNGDEFDLLAYTDPELDTG-----DKKDIFNEHLRLVESANEKAEREALLRG 3088
L GD + + P+L T + + + A ++ L +
Sbjct: 638 LNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKA 697
Query: 3089 VEPGPLGPEERPP-----PAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEP 3143
EP P + P P+A A +P A L + P E PS P +
Sbjct: 698 PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE-----PSVPSEQDKAPVADD 752
Query: 3144 APAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSG 3203
P + +KP ++ S T P S +A T PS
Sbjct: 753 KPKQPKM---VKPTTDLVSSSSAT--TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 3204 PGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKK 3263
P G + +S A+ P AS ++ S+ ++ + +KKE KK
Sbjct: 808 PTGEKV---SPFDSKAIPRP----ASDSKIISHPGPSSESKGQKQVDPV---QKKEEPKK 857
Query: 3264 QQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQP 3323
Q ++ P + + P P ++P SP ++ SL L
Sbjct: 858 AQ--TKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA 915
Query: 3324 GLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMG 3383
QP P + L ++ S +++S GQ G Q + Q P
Sbjct: 916 PKSQPTTPQETVTGKL---FGFGASIFSQASNLIS--TAGQPGPHSQSGPGAPMKQAPAP 970
Query: 3384 TMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGS 3443
+ PP+ P+ P K A + ++P A+ + +K +
Sbjct: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAE-QAPTVKRTETEKKPPP 1029
Query: 3444 IGVAPGMNRQ-QVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQ--- 3499
I + + + Q ++L +L P + + E + G P N T +
Sbjct: 1030 IKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK---TELNIGSKDPPNFNTCTECKNQV 1086
Query: 3500 ----GVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGRE 3555
G + +EWL Q + + Q+G RK A + + E
Sbjct: 1087 CNLCGFNPTPHLTEIQEWLCLNCQ----TQRAISGQLGDIRKMPPAPSGPKASPMPVPTE 1142
Query: 3556 FPE---ADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQ 3612
A ++KLV +Q+ +++ + ++V ++ + T M + Q+Q++ + ++
Sbjct: 1143 SSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEK 1202
Query: 3613 HSA 3615
A
Sbjct: 1203 DKA 1205
Score = 57.4 bits (137), Expect = 4e-07
Identities = 77/279 (27%), Positives = 104/279 (37%), Gaps = 48/279 (17%)
Query: 470 PPEELPASPLPEALHLSRPL------EESPLSPPPEESPL--SPPPESSPF---SPLEES 518
PP + A P+ E L + +E P S P SP S P + PF S L+ S
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 519 PLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE 578
PP PP PPP P PP PPP PTSP P + P +
Sbjct: 2403 AQPPPPPPPP---------PPPPPPPPPPP-------PPPLPPPTSPKP---TILPKKKL 2443
Query: 579 SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP 638
+ SP +P+ + L P +PPP + S P +
Sbjct: 2444 TVASPVTTATPLFDAVTTLETTAVLRSNGL-PVTRICTTAPPPVPPKPSSIPSGLVFTHR 2502
Query: 639 PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPED--- 695
PE P PP ++P PV+ +L P + P P+ + S + D
Sbjct: 2503 PE--PSKPP-----IAPKPVIPQL-PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKL 2554
Query: 696 -SPTSP-PPEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732
SPTSP P + +SP SL E ++ LP EP
Sbjct: 2555 PSPTSPLSPHSNKSSPRFSKSL----TETYVVITLPSEP 2589
Score = 54.3 bits (129), Expect = 3e-06
Identities = 223/1063 (20%), Positives = 335/1063 (31%), Gaps = 160/1063 (15%)
Query: 3553 GREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQ 3612
GR+ + D + ++Q KI+ Q K + T K Q+ + Q +Q
Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQ 285
Query: 3613 HSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPF 3672
V S S LP P P PP Q G + PG P QP G
Sbjct: 286 ADIVRGESVKPS------LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG-- 337
Query: 3673 LNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQ 3732
L LAQQ G P G P + LGP Q Q
Sbjct: 338 LTKPLAQQ-----PGTVKPPVQPPGTTKP---PAQPLGPAKPPAQ--------------Q 375
Query: 3733 KLQQQQQQQQQQQHLLGQ---VAIQQQQQQGPGVQTNQALG-PKPQGLMPPSSHQGLLVQ 3788
++ +Q L Q V QQ GP Q +G PKP P GL
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP-----GLQSP 430
Query: 3789 QLSPQPPQGPQGMLGPAQVAVLQQQHPG-----ALGPQGPHRQVLMTQSRVLSSPQLAQQ 3843
+P P + P GP ++ QQ PG GP P Q+ P A+
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPA-QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489
Query: 3844 GQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQ 3903
G +QQ + QQ A S Q Q SA+P QQ
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP-----SAQQP 544
Query: 3904 QQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQ--QLQQQQQQLQQQQQQ 3961
+ Q + Q + LQ + +Q Q + L + L ++
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEK 604
Query: 3962 QQQQFQQQQQQQQMGL--LNQSRTLLSPQQ----QQQQQVALGPGMPAKPLQHFSSPGAL 4015
+ Q L N + L ++ Q + ALG + P SSP
Sbjct: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP----SSPQPK 660
Query: 4016 GPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQL 4075
T +T + V + P + PE P +P+L G
Sbjct: 661 LKTAPVT--TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 4076 LLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA 4135
QP P+ SL P + P +Q ++ +
Sbjct: 719 KAKQP---PEADSLSKPAPPKEPSVPSEQ---------------DKAPVADDKPKQPKMV 760
Query: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVG 4195
+P+ L + T+ P P + Q PP + Q P G +
Sbjct: 761 KPTTDLVSSSSATTK----PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 4196 QLRAQLQGVLAKNPQLRHLSPQQ----QQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTS 4251
+A + + + + H P Q+Q+ + + + +++Q P +P + S
Sbjct: 817 DSKA-IPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGS 875
Query: 4252 PLQGLLGCQPQLG-GFPGPQTGPLQE-------LGAGPRPQGPPRLPAPPGALSTGPVLG 4303
P G +P G P PQ P + L G P P P TG + G
Sbjct: 876 PTPP--GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFG 933
Query: 4304 -------------PVHPTPPPSSPQEPKRP-SQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349
P P S P P Q P+PS PPT G PK G
Sbjct: 934 FGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ--------PPTSQGPPKSTGQ 985
Query: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHL-DQVNGQVVP 4408
P P + P + K +P A T K ++ P + D + P
Sbjct: 986 A-PPAPAKSIPVKKETKAPAAEK----LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040
Query: 4409 EASQLSIKQEPREEP---CALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLL--- 4462
+ + L K E +P C L K E N IG+ N +++ +L
Sbjct: 1041 QKAVLPTKLEKSPKPESTCPL----CKTELN---IGSKDPPNFNTCTECKNQVCNLCGFN 1093
Query: 4463 ----LQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPL 4518
L ++ + T R G +I +K+ PS + A+ P+
Sbjct: 1094 PTPHLTEIQEWLCLNCQTQRAISGQLGDI------------RKMPPAPSGPK--ASPMPV 1139
Query: 4519 TPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSL 4561
+ + A V KK +E A + +L+++K+ LS+
Sbjct: 1140 PTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSM 1182
Score = 54.3 bits (129), Expect = 3e-06
Identities = 57/218 (26%), Positives = 95/218 (43%), Gaps = 10/218 (4%)
Query: 3826 QVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSG 3885
+V+ +S +L P+ +Q Q L R + ++ +QQ+ ++ L +Q +
Sbjct: 3193 EVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEE-----LEWERQEIQRFRE 3247
Query: 3886 QPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQ 3945
Q K+ Q L++LQ +Q QQ +++Q Q + +Q+ L QQQLQ +Q QQLQQQ
Sbjct: 3248 QEKIMVQK--KLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQL-EQIQQLQQQLH 3304
Query: 3946 QQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKP 4005
QQL++Q+ + Q Q + +L L Q + A
Sbjct: 3305 QQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTASAVVA 3364
Query: 4006 LQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPST 4043
++ S G T+ G Q P + S +E P T
Sbjct: 3365 IEIPQSQGWY--TVQSDGVTQYIAPPGILSTVSEIPLT 3400
Score = 53.9 bits (128), Expect = 4e-06
Identities = 80/293 (27%), Positives = 110/293 (37%), Gaps = 33/293 (11%)
Query: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
P P P S + P R S L + ++ PPP PPP P PPP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP----PPPPPPPPPPPP---- 2423
Query: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE--EPQLCPRSEGPHLSPR 746
PPP PTSP P P + ++ S +PL E RS G ++ R
Sbjct: 2424 --PPPLPPPTSPKP---TILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT-R 2477
Query: 747 PEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP-HLSPQPEELH 805
P P +P P P+P +P + P P L + P + P+P L
Sbjct: 2478 ICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLS 2537
Query: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
L T L+ V P P S LSP S + SPR S L + +
Sbjct: 2538 L---TSSMTLNLVTSADYKLPSP-TSPLSPHSNKS--SPR-----FSKSLTETYVVITLP 2586
Query: 866 KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS 918
P P A + + + P G PS + EP S PP++ + E+P+S
Sbjct: 2587 SEPGTPTDSSASQAITSW-PLGSPSKDLVSVEPVFSV--VPPVTAV--EIPIS 2634
Score = 52.8 bits (125), Expect = 1e-05
Identities = 166/813 (20%), Positives = 258/813 (31%), Gaps = 125/813 (15%)
Query: 3723 LQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQ---QGPGV-----------QTNQA 3768
LQQQ + K Q + QQ ++ QQ ++ Q PG QT+ A
Sbjct: 211 LQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA 270
Query: 3769 LGPKPQGLMPPSSHQGLLVQQLSPQPP---------QGPQGMLGPAQVAVLQQQHPGALG 3819
P + P + Q +V+ S +P Q P PAQ ++ PG
Sbjct: 271 KLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAK 330
Query: 3820 PQG-------PHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAG 3872
P P Q T + P + +G AQQ ++ +Q
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA 390
Query: 3873 LSH---LQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQ--------LQQQQQQQLQ 3921
L+ + ++ G K Q +G+ + L QQ LQ + +QQ ++
Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP 450
Query: 3922 QQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981
QQ + QQ + Q + QQ + QQ + QQ G
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Query: 3982 RTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGP 4041
P + QQ PG P Q PG+ P+ ++ + P+
Sbjct: 511 PQQPGPAKPSPQQ----PGSTKPPSQQ---PGSAKPS----AQQPSPAKPSAQQSTKPVS 559
Query: 4042 STHQGGPLAIGTTPESMATEPGEVKPS----LSGDSQLLLVQPQP--------------- 4082
T G PL T S P + P L ++LLL P+
Sbjct: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619
Query: 4083 ----QPQPSSLQLQPPLRLPGQQQQQVSL-LHTAGGGSHGQLGSGSSSEASSVPHLLAQP 4137
P P +++ L L Q ++ + L +L + + S+V QP
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP 679
Query: 4138 SVSLGDQPGSMTQNLLGPQQPMLERPMQNNT----GPQPPKPGPVLQSGQGLPGVGIMPT 4193
+ + + Q+L +P P+ P P P P+
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPS 739
Query: 4194 VG--QLRAQLQGVLAKNPQL----RHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPG 4247
V Q +A + K P++ L + + ++Q + TPP +
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDS 799
Query: 4248 TQTSPLQGLLGCQPQLGGFP--GPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPV 4305
+ S FP G + P A PRP ++ + PG S V
Sbjct: 800 AKPSQ------------SFPPTGEKVSPFDSK-AIPRPASDSKIISHPGPSSESKGQKQV 846
Query: 4306 HPTPPPSSPQE------PK-----RPSQLPSPSSQLPTEAQLPPTHPGTPKPQ------- 4347
P P++ PK P P+P PT Q PT +PKPQ
Sbjct: 847 DPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFS 906
Query: 4348 ---GPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAET--QKPEQSSLVPG-HLDQ 4401
G + P + + + LF G + NL T Q S PG + Q
Sbjct: 907 LNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ 966
Query: 4402 VNGQVVPEASQLSIKQEPREEPCALGAQSVKRE 4434
P SQ K + P + VK+E
Sbjct: 967 APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKE 999
Score = 47.8 bits (112), Expect = 3e-04
Identities = 71/274 (25%), Positives = 94/274 (34%), Gaps = 41/274 (14%)
Query: 2350 QEPPPAQALAPSP-----PSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLP 2404
QE P +Q + SP P+ P F S D AQPP P P PPPP PP P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP------PPPPPP 2422
Query: 2405 SDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFA 2464
P P SP+ + LT SPVT D + + R
Sbjct: 2423 PPPPLPPPTSPKPTILPKKKLT---------VASPVTTATPLFDAVTTLETTAVLRSNGL 2473
Query: 2465 PLHK----PPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVR 2520
P+ + P P PP+ + L T P+ P P + + Q P +
Sbjct: 2474 PVTRICTTAPPPVPPKPSSIPSGLVFTHRPE---PSKPPIAPKPVIPQLPTTTQKPTDIH 2530
Query: 2521 SPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNY 2580
TG + + + V K P P L P +S P K + Y
Sbjct: 2531 PKPTGLSLTSSMTLNL-----VTSADYKLPSPTSPLSPHSNKSS-----PRFSKSLTETY 2580
Query: 2581 TVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPS 2614
V T PS P P+ S ++ PL PS
Sbjct: 2581 VVIT---LPS-EPGTPTDSSASQAITSWPLGSPS 2610
Score = 45.8 bits (107), Expect = 0.001
Identities = 115/513 (22%), Positives = 169/513 (32%), Gaps = 52/513 (10%)
Query: 498 PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPP 557
P ES S PP +P S + + S P L++ + E + FE+S
Sbjct: 2169 PSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDS----- 2223
Query: 558 PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPL 617
EE+ +S S + P E S +P A + + S P
Sbjct: 2224 -EEISSSTYFPGSIIDYPEEISVSLD--RTAPPDGRASADHIVISLSDMASSIIESVVPK 2280
Query: 618 SPPPEASRLSPP---PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
P A +S E P+ +E+ EV L L +S LS
Sbjct: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEV--LEAYRDKKELEAERTKSSLS-- 2336
Query: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734
E+ PP + P E T+ S + E LP + LP +P+
Sbjct: 2337 --ETVFDHPPSSVIALPMKEQLSTTY--FTSGETFGQEKPASQLPSGSPSVSSLPAKPRP 2392
Query: 735 CPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794
RS +S +P P P P P P P P +P + + SP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA 2452
Query: 795 PHLSPQPEELHLSPQTEEPHL----------SPVPEEPCLSPQPEESHLSPQSEEPCLSP 844
L L + L PVP +P P P+ +P ++P
Sbjct: 2453 TPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAP 2512
Query: 845 RPEESHLSPELEKP-PLSPRP-----------EKPPEEPGQCPAPEELPLFPPPGE--PS 890
+P L +KP + P+P + P+P PL P + P
Sbjct: 2513 KPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTS-PLSPHSNKSSPR 2571
Query: 891 LSPLLGEPAL-----SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPP--DPLPPPLSPII 943
S L E + SEPG P S + + P G PS + P +PP + I
Sbjct: 2572 FSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEI 2631
Query: 944 TAAAPPALSPLGELEYPFGAKGDSDPESPLAAP 976
++ G L+ F A + P S AAP
Sbjct: 2632 PISSEQTFYISGALQ-TFSATPVTAPSSFQAAP 2663
Score = 45.4 bits (106), Expect = 0.002
Identities = 51/205 (24%), Positives = 71/205 (34%), Gaps = 21/205 (10%)
Query: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS 477
P G V P P L + P PPP P PPP PPP P S
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP----PPPPLPPPTS 2432
Query: 478 PLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET--- 534
P P L + SP++ + P + LE + + P + T
Sbjct: 2433 PKPTILPKKKLTVASPVT--------TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPP 2484
Query: 535 PLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPP 594
P+ P P + P F P P + P +P P +L P + P P+ + +S
Sbjct: 2485 PVPPKPSSIPSGLVFTH---RPEPSKPPIAPKPVIPQL-PTTTQKPTDIHPKPTGLS--L 2538
Query: 595 EASRLFPPFEESPLSPPPEESPLSP 619
+S + P SPLSP
Sbjct: 2539 TSSMTLNLVTSADYKLPSPTSPLSP 2563
Score = 42.4 bits (98), Expect = 0.013
Identities = 68/317 (21%), Positives = 109/317 (34%), Gaps = 68/317 (21%)
Query: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206
+G G + P P V + PF + + + + P PP PP P P P
Sbjct: 2363 SGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP 2422
Query: 2207 AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG 2266
PP+ PP P++P P + P+ L V
Sbjct: 2423 PPPPL------------------PP------PTSPKPTILPK----KKLTV--------- 2445
Query: 2267 KASEPLLSPPPFGESRKALE---------VKKEELGASSPSYGPPNLGFVDSPSSGTHLG 2317
+ P+ + P ++ LE + + ++P PP + S TH
Sbjct: 2446 --ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTH-- 2501
Query: 2318 GLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE-PPPAQALAPSPPSHPDIFRPGSYTD 2376
P+ K P+ P+ V PQ P +P + P L+ + ++ Y
Sbjct: 2502 -----RPEPSKPPIAPK--PVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKL 2554
Query: 2377 PYAQPPLTPRPQPPPPESCCALPPR----SLPSDPFSRVPASPQSQSSSQSPLTPRPLSA 2432
P PL+P P +L +LPS+ P +P S+SQ+ +T PL +
Sbjct: 2555 PSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSE-----PGTPTDSSASQA-ITSWPLGS 2608
Query: 2433 EAFCPSPVTPRFQSPDP 2449
+ V P F P
Sbjct: 2609 PSKDLVSVEPVFSVVPP 2625
Score = 40.8 bits (94), Expect = 0.038
Identities = 68/279 (24%), Positives = 97/279 (34%), Gaps = 39/279 (13%)
Query: 835 PQSEEPCLSP-------RPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPG 887
P S+ P SP +P S L+ P P PP P P P P PPP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 888 EPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAA 947
P +L + L+ SP+ PL + + ++ + L P++ I T A
Sbjct: 2432 SPK-PTILPKKKLT-----VASPVTTATPLFDAVTTLETTAVLRSNGL--PVTRICTTAP 2483
Query: 948 PPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007
PP P P G PE S PP A P+PV P +
Sbjct: 2484 PPV--PPKPSSIPSGLVFTHRPEP-----------SKPPIA----PKPVIPQL------- 2519
Query: 1008 PVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDE 1067
P P + P P S +L S + P PLS S S +++
Sbjct: 2520 PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTET 2579
Query: 1068 AELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAP 1106
+ + +E + + A + + PL SP DL P
Sbjct: 2580 YVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEP 2618
Score = 40.0 bits (92), Expect = 0.064
Identities = 31/91 (34%), Positives = 40/91 (43%), Gaps = 15/91 (16%)
Query: 4881 QESPAPEPPTQHSYTYNVSNLDVR----------QLSAPPPEEPSPPPSPLAPSPASPPT 4930
QE PA + P S + +VS+L + +SA PP P PPP P P P PP
Sbjct: 2369 QEKPASQLP---SGSPSVSSLPAKPRPFFRSSSLDISAQPP--PPPPPPPPPPPPPPPPP 2423
Query: 4931 EPLVELPTEPLAEPPVPSPLPLASSPESARP 4961
P + PT P L +AS +A P
Sbjct: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 39.7 bits (91), Expect = 0.084
Identities = 48/184 (26%), Positives = 74/184 (40%), Gaps = 25/184 (13%)
Query: 520 LSPPEESPPSPAL------ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEAS--- 570
+S PE++ +L ++ P S SPP ++ P P E+ S A
Sbjct: 3553 ISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKK--RPTPLEIGYSSHLRADSTV 3610
Query: 571 RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE------SP---LSPPPEESPLSPPP 621
+L+P P +SP SP+SP F P+E+ SP L P + P + P
Sbjct: 3611 QLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPK 3670
Query: 622 EASRLSPPPED-SPMSPPPEESPMSP----PPEVSRLSPLPVVSRLSPPPEESPLSPPPE 676
A + D P+SP +ES +P ++ S S + + +PPPE
Sbjct: 3671 TAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPE 3730
Query: 677 ESPT 680
E T
Sbjct: 3731 EIST 3734
Score = 39.3 bits (90), Expect = 0.11
Identities = 40/132 (30%), Positives = 53/132 (40%), Gaps = 19/132 (14%)
Query: 446 ESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP 505
+S P S TSPP + R P P E+ S A + P SP SP+SP
Sbjct: 3572 DSDTQSPQYLSATSPPKDKKR--PTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP 3629
Query: 506 PPESSPFSPLE------ESPLSPPEESPPSPALETPLSPPPEASPLSPPF------EESP 553
SP LE E PL P++ P L ++ P ASP + + P
Sbjct: 3630 ---LSPGKALESAFVPYEKPL--PDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKP 3684
Query: 554 LSPPPEELPTSP 565
LSP +E +P
Sbjct: 3685 LSPTADESSRAP 3696
Score = 38.5 bits (88), Expect = 0.19
Identities = 81/346 (23%), Positives = 123/346 (35%), Gaps = 67/346 (19%)
Query: 4617 SNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDL 4676
S P +S+PP+ PS+ + + T +S + +LD
Sbjct: 2167 SEPSESATSVPPSDTPSLTSSVSSVCTTDS---------------------SSPITTLDS 2205
Query: 4677 LAALPTPPHNQTEDVRMESDEDSDS---PDSIVPASSPESI-LGEEAPRFPHLGSGRW-- 4730
+ + T P + +S+E S S P SI+ S+ L AP +
Sbjct: 2206 ITTVYTEPVDMITKFE-DSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVI 2264
Query: 4731 EQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSA 4790
D A S + ++P+ PV DT + L + K PV +K G+ + + + +
Sbjct: 2265 SLSDMASSIIESVVPKPEGPV-ADTV---STDLLISEKDPVKKAKKETGNGIILEVLEAY 2320
Query: 4791 AAAKNLNGVMV--AVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGK 4848
K L +++E + P+S + P + T GE G L
Sbjct: 2321 RDKKELEAERTKSSLSETVFDHPPSSV-IALPMKEQLSTTYFTSGETFGQEKPASQLPSG 2379
Query: 4849 SPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSA 4908
SP + A + S LDI + + P P PP
Sbjct: 2380 SPS-----VSSLPAKPRPFFRSSSLDISA----QPPPPPPP------------------- 2411
Query: 4909 PPPEEPSPPPSPLAPSPASPPTEPL-VELPTEPL-AEPPVPSPLPL 4952
PPP P PPP P P P PPT P LP + L PV + PL
Sbjct: 2412 PPPPPPPPPPPP--PPPLPPPTSPKPTILPKKKLTVASPVTTATPL 2455
Score = 37.4 bits (85), Expect = 0.42
Identities = 52/213 (24%), Positives = 74/213 (34%), Gaps = 12/213 (5%)
Query: 460 PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP 519
P E L+ PE+ +LH S +P + P S L +SSP ES
Sbjct: 1697 PELEMESLTDSPEDRSRGEGSSSLHAS---SFTPGTSPTSVSSLDEDSDSSPSHKKGESK 1753
Query: 520 LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579
P L + E L E E+ +S+ S ++
Sbjct: 1754 QQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDE 1813
Query: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP 639
+ E P +PP S P E++ SP E + E R S + P
Sbjct: 1814 LRAQRRRERPKTPPSNLS----PIEDA--SPTEELRQAAEMEELHRSSCSEYSPSIESDP 1867
Query: 640 EESPMSPPP--EVSRLSPLP-VVSRLSPPPEES 669
E +SP EV ++ LP VS SP E+S
Sbjct: 1868 EGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQS 1900
Score = 36.2 bits (82), Expect = 0.93
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 4548 SEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQL-RGAFGSGALPTGPDY 4606
SE + + LP+ E T F+ FG P SQL G+ +LP P
Sbjct: 2336 SETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPA---SQLPSGSPSVSSLPAKPRP 2392
Query: 4607 YSQLLTKNNLSNPPTPPSSLPPTPPP 4632
+ + + + + PP PP PP PPP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPP 2418
Score = 36.2 bits (82), Expect = 0.93
Identities = 49/195 (25%), Positives = 70/195 (35%), Gaps = 17/195 (8%)
Query: 2107 PPQPGALGSPPPAAAPTIF------IGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELF 2160
PP P PP + PTI + SP T A A L+ A +
Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRIC 2479
Query: 2161 LKLPPQVPAQVPSQDPFGLAPAYPLEP-RFPTAP-PTYPPYPSPTGAPA----QPPMLGA 2214
PP VP + PS P GL + EP + P AP P P P+ T P +P L
Sbjct: 2480 TTAPPPVPPK-PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSL 2538
Query: 2215 SSRPGAG--QPGEFHTTPPGTP--RHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASE 2270
+S ++ P +P H + F K + + +P PG ++
Sbjct: 2539 TSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSAS 2598
Query: 2271 PLLSPPPFGESRKAL 2285
++ P G K L
Sbjct: 2599 QAITSWPLGSPSKDL 2613
Score = 35.8 bits (81), Expect = 1.2
Identities = 25/68 (36%), Positives = 26/68 (38%), Gaps = 10/68 (14%)
Query: 4275 QELGAGPRPQGPPR---LPAPPGALSTGPVLG-------PVHPTPPPSSPQEPKRPSQLP 4324
QE A P G P LPA P L P P PPP P P P LP
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 4325 SPSSQLPT 4332
P+S PT
Sbjct: 2429 PPTSPKPT 2436
Score = 35.4 bits (80), Expect = 1.6
Identities = 35/118 (29%), Positives = 48/118 (40%), Gaps = 21/118 (17%)
Query: 4276 ELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQE---PKRPSQLPSP------ 4326
++ A P P PP P PP P P P PPP+SP+ PK+ + SP
Sbjct: 2400 DISAQPPPPPPPPPPPPPP-----PPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Query: 4327 ----SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
+ L T A L G P + T PPP P++ + +F+ P PP
Sbjct: 2455 LFDAVTTLETTAVLRSN--GLPVTRICTTAPPPVPPKPSSIP-SGLVFTHRPEPSKPP 2509
Score = 34.7 bits (78), Expect = 2.7
Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 6/83 (7%)
Query: 4297 STGPVLGPVHPTP--PPSSPQEPKRPSQLPSP---SSQLPTEAQLPPTHPGTPKPQGPTL 4351
++G G P P SP P++ P P SS L AQ PP P P P P
Sbjct: 2362 TSGETFGQEKPASQLPSGSPSVSSLPAK-PRPFFRSSSLDISAQPPPPPPPPPPPPPPPP 2420
Query: 4352 EPPPGRVSPAAAQLADTLFSKGL 4374
PPP + P + L K L
Sbjct: 2421 PPPPPPLPPPTSPKPTILPKKKL 2443
Score = 33.9 bits (76), Expect = 4.6
Identities = 51/184 (27%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 695 DSPTSPPPEDSPASPPPEDSLMSLPLE--ESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL 752
DS T P S A+ PP+D PLE S L QL P SP P+ P +
Sbjct: 3572 DSDTQSPQYLS-ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAP-------SP-PKSPKV 3622
Query: 753 SPRPEEPHLSP-----QAEEPHLSPQPEEPCLCAVPEEPHLSPQAE-GPHLSPQPEELHL 806
P P LSP A P+ P P++ +SPQ P ++ P
Sbjct: 3623 LYSPISP-LSPGKALESAFVPYEKPLPDD-----------ISPQKVLHPDMAKVPPA--- 3667
Query: 807 SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEK 866
SP+T + + + LSP +ES +P + + ++ S +K P
Sbjct: 3668 SPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNP 3727
Query: 867 PPEE 870
PPEE
Sbjct: 3728 PPEE 3731
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 150 bits (379), Expect = 3e-35
Identities = 198/692 (28%), Positives = 255/692 (36%), Gaps = 145/692 (20%)
Query: 441 LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALH-LSRPLEESPLSPPPE 499
LP P S PP E P AS S A P A L RP S S
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS---S 245
Query: 500 ESPLSPPPESSPFSPLEESPLSPPEESPPSP----ALETPLSPPP--EASPLSPPFEESP 553
+PLS P S P + +P +P S P P AL P PP +A+P P SP
Sbjct: 246 ATPLSSPARSGPSA--RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 554 LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE 613
L+ +P P A+ S P P +P +L P PL+PP
Sbjct: 304 LA--------TPSPSAALQSQAPPTLPATPHSSSL-------TCQLATPL---PLAPP-- 343
Query: 614 ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673
SP +PP + SPP +PP + + P L P P SPL+
Sbjct: 344 -SPSAPPSLQTLPSPPA-----TPPSQATTSLGSPT------LQATHSFLPSPPLSPLAT 391
Query: 674 PPEESPTSPPPEASRLSPPPEDSPTSPP--PEDSP-ASPPPE-DSLMSLPLEESPLLPLP 729
PP P +PP L+ PP +P SPP P SP A+P P+ + +++ L ++P P P
Sbjct: 392 PP---PQAPP----ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444
Query: 730 EEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLS 789
P P S P P +SP A P +P P L A P + S
Sbjct: 445 SPPVQAPFSP----------------PASPPVSPSATPPSQAP----PSLAAPPLQVPPS 484
Query: 790 PQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEES 849
P A P +SP P +P P +P + + PQ+
Sbjct: 485 PPASPP----------MSPSATPPPQAP---PPLAAPPLQLAKPPPQA------------ 519
Query: 850 HLSPELEKPPLSPRPEKPPEEPGQCP--APEELPLFP---PPGEPSLSPLLGEPALSEPG 904
P L PPL P P PGQ P LP+ P PP P P+L P L P
Sbjct: 520 --PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP--PQAPPVLAAPLLQVPP 575
Query: 905 EPPLSPL-------PEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP-ALSPLGE 956
PP SP P P + P L+ L P P PP SP T + P A
Sbjct: 576 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 635
Query: 957 LEYPFGAKG-DSDPESPLAAPILETPISPPPEANCT-------DPEPVPPMILPPSPGSP 1008
P +G DS PE AA SPPP+A P PP+ +PG+P
Sbjct: 636 TSTPEELRGYDSGPEGGAAA-------SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 688
Query: 1009 VGPASPILMEPLPPQCSPLLQHSL--VPQNSPPSQCSP-PALPLSVPSPLSPIGK-VVGV 1064
+ P PP P L + + P +P P PSP + GK G
Sbjct: 689 L---------PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 739
Query: 1065 SDEAELHEMETEKVSEPECPALEPSATSPLPS 1096
A + ++ E AL+ S L S
Sbjct: 740 GAGASSRSPKQARLGELPLGALQASVVQHLLS 771
Score = 139 bits (349), Expect = 1e-31
Identities = 201/753 (26%), Positives = 257/753 (34%), Gaps = 137/753 (18%)
Query: 494 LSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPL----SPPPEASPLSPPF 549
L+P P SP PPP +P L P E + PE++P + P
Sbjct: 25 LTPRPPGSPRPPPP----VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80
Query: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP--FEESP 607
+ S P S PP + R P SP P+S P AS P +
Sbjct: 81 RSAGTS---SRNPASRPPASGRGERAPPAKNTSP----GPVSSPGRASGTTRPGPLGQKG 133
Query: 608 LSPPPEES----PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLS--------- 654
L EE+ + P+ S LS P +P +P P ++R S
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGP----TPGTPSPAMARRSRAAGTEVGL 189
Query: 655 PLPVVSRLSPPPEESP---LSPPPEESPTSPPPEASRLS--------PPPEDSPTSPPPE 703
P P S PP E P +S E S T P P A R P +S P
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 704 DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE--PHLSPRPEEPHL 761
SPA P S P +P P +P+ P ++P ++ P L P P
Sbjct: 250 SSPARSGP--SARGTP--RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
Query: 762 SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEE--PHLSPVP 819
+P S P P L A P L+ Q P L L+P + P L +P
Sbjct: 306 TPSPSAALQSQAP--PTLPATPHSSSLTCQLATP--------LPLAPPSPSAPPSLQTLP 355
Query: 820 EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEE 879
P P + L SP + +H L PPLSP PP+ P P
Sbjct: 356 SPPATPPSQATTSLG--------SPTLQATHSF--LPSPPLSPLATPPPQAPPALALPPL 405
Query: 880 LPLFPPPGEPSLSPL----------LGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929
PP P LSPL L L P PP SP P + P SP P +SP
Sbjct: 406 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPSA 464
Query: 930 MPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEAN 989
PP PP L AAPP P SP A+P + +PPP+A
Sbjct: 465 TPPSQAPPSL------AAPPL----------------QVPPSPPASPPMSPSATPPPQAP 502
Query: 990 CTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPL 1049
PP+ PP + P +P + P Q P S Q S P PL
Sbjct: 503 -------PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555
Query: 1050 SVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCP----- 1104
+ P P +P V+ A L ++ S P P L+ P P P +S P
Sbjct: 556 ATPPPQAP--PVLA----APLLQVPP---SPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 606
Query: 1105 -APSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPV 1163
AP P P ++ L G D G TP EL+G + A
Sbjct: 607 LAPGPPPPPS-----RSPSSTLSGPDLAGHSSSATSTP----EELRGYDSGPEGGAAASP 657
Query: 1164 TPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTP 1196
P C A P AP AP P
Sbjct: 658 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 690
Score = 133 bits (335), Expect = 4e-30
Identities = 132/406 (32%), Positives = 167/406 (41%), Gaps = 79/406 (19%)
Query: 406 PKEPGPLQCEAKPLGKAGVQLEPQLEAP-LNEEMPLLPPPEESPLSPPPEESPTS----- 459
P P LQ P Q L +P L LP P SPL+ PP ++P +
Sbjct: 345 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 404
Query: 460 -----PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSP 514
PP + LSP P +P A+HL ++P SPPP PP +PFSP
Sbjct: 405 LQAPPSPPASPPLSPLATPSPQAPNALAVHLL----QAPFSPPPS------PPVQAPFSP 454
Query: 515 LEESPLS----PPEESPPS---PALETPLSPP------PEASPLSPPFEESPLSPPPEEL 561
P+S PP ++PPS P L+ P SPP P A+P PP PL+ PP +L
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP--PPQAPPPLAAPPLQL 512
Query: 562 PTSPPPEASRLSPPPEESPMSPP---PEESPMSPPPEASRLFPPFEESPLSPPPEESPLS 618
PP L+ PP ++ SPP P ++P SP SPL+ PP ++P
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS-------LPMSPLATPPPQAP-- 563
Query: 619 PPPEASRLSPPPEDSPMSPPPEESPMSPP---PEVSRLSP---LPVVSRLSPPPEESP-- 670
P A L PP SP + P ++P PP P+ S P L + PPP SP
Sbjct: 564 PVLAAPLLQVPP--SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 621
Query: 671 -LSPPP----EESPTSPPPEASRLSPPPE-DSPTSPPPEDSPASPPP----EDSLMSLPL 720
LS P S TS P E PE + SPPP+ A+ P L
Sbjct: 622 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 681
Query: 721 EESPLLPLPEEPQLCPRS----------EGPHLSPRPEEPHLSPRP 756
+P PLP P P S EGP S P L P P
Sbjct: 682 RGAPGAPLPWPPATGPGSADGLCTIYETEGPE-SATPAPGALDPGP 726
Score = 116 bits (290), Expect = 7e-25
Identities = 187/695 (26%), Positives = 243/695 (34%), Gaps = 97/695 (13%)
Query: 2053 PAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGA 2112
PAA + P A+ ++ + + ++ + G AR T R H P G
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSS----SATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277
Query: 2113 LGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVP 2172
PP P P + A G L + P P + L + PP +PA
Sbjct: 278 QALRPPQVTP---------PRKDAAPALGPLSSSPLATPSPSAA--LQSQAPPTLPATPH 326
Query: 2173 SQD-PFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPP 2231
S LA PL P P+APP+ PSP PA PP +S G+ H+ P
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSP---PATPPSQATTSL-GSPTLQATHSFLP 382
Query: 2232 GTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEE 2291
P +TP P P +L L P SP PL +P P + A+ + +
Sbjct: 383 SPPLSPLATPPPQAPPAL-ALPPLQAPPSPPAS--PPLSPLATPSPQAPNALAVHLLQAP 439
Query: 2292 LGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE 2351
SP PP P+S P++P A+ P L P +
Sbjct: 440 F---SPPPSPPVQAPFSPPAS----------------PPVSPSATPPSQAPPSLAAPPLQ 480
Query: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL---TPRPQPP-----PPESCCALPPRSL 2403
PP+ SPP P P P A PPL P PQ P PP PP S
Sbjct: 481 VPPSPPA--SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 538
Query: 2404 PSD-PFSRVPASPQSQSSSQSPLTPRPLSAEAF--CPS-PVTPRFQSPDPYSRPP----- 2454
P PFS + P S ++ P P L+A PS P +P Q+P RPP
Sbjct: 539 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP---RRPPTPGPD 595
Query: 2455 ---SRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511
S P+ AP PP + P LA S A P L +G
Sbjct: 596 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 655
Query: 2512 SGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPT 2571
S P + + A+ P+P F A G P PP PG G+ + + T
Sbjct: 656 SPPPDAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWPPATGPG--SADGLCTIY---ET 709
Query: 2572 LGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHG 2631
G P+S T A G P SP G S G G S P A G LP G
Sbjct: 710 EG-PESA--TPAPGALDPGPSP-GTSGGKAAAGAGAG---ASSRSPKQARLGELPL---G 759
Query: 2632 ASQRSGI------TSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQR 2685
A Q S + T + E G G AE G + LS EL R
Sbjct: 760 ALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAEL------GR 813
Query: 2686 LRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSW 2720
ELL R ++ T+ + P G W
Sbjct: 814 WAELLSPLDESRASI--TSVTSFSPDDVASPQGDW 846
Score = 98.2 bits (243), Expect = 2e-19
Identities = 203/817 (24%), Positives = 263/817 (32%), Gaps = 186/817 (22%)
Query: 2087 QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPP 2146
+ K G AR A L P PG+ PPP + + G A+
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE-----R 61
Query: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYP-PYPSP--T 2203
AG + G P E + P A S++P PA R P A T P P SP
Sbjct: 62 AGGIGGATIP-ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
Query: 2204 GAPAQPPMLG----------------ASSRP-----GAGQPGEFHTTPPGTPRHQPS--- 2239
+P LG A+ P AG + PGTP +
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 2240 ----------TPDPFLKPRCP----------------SLDNLAVPESPGVGGG------- 2266
P P +PR P + + A P GGG
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 2267 ---KASEPLLSPPPFGESRKAL--------EVKKEELGASSPSY-------GPPNLGFVD 2308
++ PL SP G S + + K + L A P P LG +
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 2309 SPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ-SPGLGLRPQEP--PPAQALAPSPPSH 2365
S T L++ P TP +S + Q + L L P P PP+ PSPP+
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
Query: 2366 PDIFRPGSYTDPYAQ--------PPLTPRPQPPP-PESCCALPPRSLPSDPFSRVPASPQ 2416
P S P Q PPL+P PPP ALPP P P + P SP
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
Query: 2417 SQSSSQ--------------------------SPLTPRPLSAEAFCPSPVTPRFQSPDPY 2450
+ S Q SP P+S A PS P +P P
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP-PL 479
Query: 2451 SRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKV 2510
PPS P S P +P PP PP +A LA A P AL P L +
Sbjct: 480 QVPPSPPAS-PPMSPSATPPPQAPPPLAAPPLQLAKPPPQA---PPALATPPLQALPSPP 535
Query: 2511 PS--GQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGP 2568
S GQ P + + + TP P P + P L+ P P P P
Sbjct: 536 ASFPGQAPFSPSASLPMSPLATPPPQA---PPVLAAPLLQVPPSPPASPTLQAPRRPPTP 592
Query: 2569 GP--TLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL---------- 2616
GP ++ P+ T PS SP SG + S P L
Sbjct: 593 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 652
Query: 2617 --PPPAPDGSLPYLSHGASQRSGITSPVEKREDPG--------TGMGSS----------- 2655
P PD L H A+ G P+ R PG TG GS+
Sbjct: 653 AAASPPPDAELA-ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 711
Query: 2656 -LATAELPGTQDPGMS----------GLSQTELEKQRQRQRLREL--------LIRQQIQ 2696
+ PG DPG S G + ++ RL EL +++ +
Sbjct: 712 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLS 771
Query: 2697 RNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLS 2733
R L E AA +G GP G+ G + A LS
Sbjct: 772 RTLLLAAAEGAAGGSGG-GPGGAEGGGVTGGARAALS 807
Score = 75.5 bits (184), Expect = 1e-12
Identities = 184/794 (23%), Positives = 262/794 (32%), Gaps = 174/794 (21%)
Query: 2213 GASSR-PGAGQPGEFHTTPPGTPRHQPSTPDPFLK--------------PRCPSLDNLAV 2257
GA++R P A PG PPG+PR P L+ R + +
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 2258 PES-PGVG-----GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSP- 2310
PES P G G + P PP G +A K +SP G V SP
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN-----TSP-------GPVSSPG 118
Query: 2311 -SSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIF 2369
+SGT G PL + ++ + + E P AL+
Sbjct: 119 RASGTTRPG-----------PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP 167
Query: 2370 RPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRP 2429
PG+ + A+ + P + PR P V ++ + ++ SP R
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
Query: 2430 LSAEAFCPSPVTPRFQSP-DPYSRPP-SRPQSRD-PFAPLH-KPPRPQ------PPEVAF 2479
SA P + S P S P S P +R P AP H P+P+ PP+V
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287
Query: 2480 KAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFP 2539
A P A P+ P+ L ++ P P S + TP P+ P
Sbjct: 288 PRKDAAPALGPLSSSPLATPS-PSAALQSQAPPTLPAT-PHSSSLTCQLATPLPLAPPSP 345
Query: 2540 QAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSG 2599
A PSL+ +P P PP + G PTL AT +F PS
Sbjct: 346 SA--PPSLQT-LPSPPATPPSQATTSLG-SPTLQ---------ATHSFLPS--------- 383
Query: 2600 STGESYGLSPLRPPSVLPPPAPDG-SLPYLSHGASQRSGITSPVEKREDPGTGMGSSLAT 2658
PL P + PP AP +LP L S + + P+ P ++LA
Sbjct: 384 --------PPLSPLATPPPQAPPALALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAV 433
Query: 2659 AELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPG 2718
L P S Q A + PP
Sbjct: 434 HLLQAPFSPPPSPPVQ---------------------------------APFSPPASPPV 460
Query: 2719 SWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDD-------- 2770
S A P S A L+ + + +PPS + P + P + P
Sbjct: 461 SPSATPPSQAPPSLA------------APPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508
Query: 2771 --RLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPY--PGSLPLQQQQQQLWQQQQATAA 2826
+L++PPP A P+ + L +F +AP+ SLP+ Q AA
Sbjct: 509 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
Query: 2827 TSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQK 2886
++ S P++P + R+ PGP V GP +
Sbjct: 569 PLLQVPPSP--PASPTLQAPRR----------PPTPGPDTSVSGP-----------RLTL 605
Query: 2887 GLGPGGTPFPGQGPPQRPRFYPVS--EDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNN 2944
L PG P P + P ++ PE LRG S PP EL
Sbjct: 606 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL-A 664
Query: 2945 SLHPTPHTKGPTLP 2958
+ HP ++GP P
Sbjct: 665 ACHPAAWSRGPAPP 678
Score = 72.0 bits (175), Expect = 2e-11
Identities = 138/555 (24%), Positives = 180/555 (32%), Gaps = 85/555 (15%)
Query: 2449 PYSRPPSRPQSRDPFAPLHKPP-RPQPPEVAFKAGS-----LAHTSLGAGGFPAALPAGP 2502
P +R P R P +P PP P V AG+ LA + G GG A
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI 2562
AG + S + P R P +G P P + T P V P +PG G+
Sbjct: 77 AGPTRSAGTSSRNPAS-RPPASGRGERAP-PAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134
Query: 2563 NSHFGPGPTLGK----PQSTNYTVATGNFHPSGSPLGPS------SGSTGESYGLSPLRP 2612
GK P+ + + +P PS S + G GL P
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL-PRPA 193
Query: 2613 PSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTG---------MGSSLATAELPG 2663
PS P P +G +S + + SP +R G + SS P
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 2664 TQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAE 2723
P G + + + + + L Q+ AA A+GP S
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT--------PPRKDAAPALGPLSSSPLA 305
Query: 2724 PSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSS 2783
SP+ S+ T SSL + L P + PS L P PPATP S
Sbjct: 306 TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL--PSPPATPPS 363
Query: 2784 MDVNSRQLVGGS---QAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPST 2840
S GS QA + P P PL Q A ++ PS
Sbjct: 364 QATTSL----GSPTLQATHSFLPSPPLSPLATPPPQ--------APPALALPPLQAPPSP 411
Query: 2841 PG-PELGRQALGSPLAGISTR---LPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFP 2896
P P L A SP A + L P P P P A F P
Sbjct: 412 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-----------------P 454
Query: 2897 GQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPA-PELNNSLHPTPHTKGP 2955
PP P P S+ P LA P Q P +PPA P ++ S P P P
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAP----------PLQVPPSPPASPPMSPSATPPPQAPPP 504
Query: 2956 TLPTGLELVNRPPSS 2970
L+L PP +
Sbjct: 505 LAAPPLQLAKPPPQA 519
Score = 68.2 bits (165), Expect = 2e-10
Identities = 106/399 (26%), Positives = 137/399 (34%), Gaps = 58/399 (14%)
Query: 4023 GKEQNTVDPAVSSEATEGPSTHQGGPLAIGTT----------PESM-ATEPGEVKPSLSG 4071
G Q ++SS AT S + GP A GT P+ + A P +V P
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291
Query: 4072 DSQLL---LVQPQPQPQPSS-LQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEA 4127
+ L P P PS+ LQ Q P LP A + L S S
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA---TPLPLAPPSPSAP 348
Query: 4128 SSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSG--QGL 4185
S+ L + P+ S+ L L P + PP+ P L Q
Sbjct: 349 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP 408
Query: 4186 PGVGIMPTVGQLRA---QLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPP 4242
P P + L Q LA + SP +QA + TPP
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVSPSATPP 467
Query: 4243 YQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVL 4302
Q P + +P L P P P A P PQ PP L APP L+ P
Sbjct: 468 SQAPPSLAAP---------PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518
Query: 4303 GP---------VHPTPPPSSP-QEPKRPS-QLP-SPSSQLPTEA---------QLPPTHP 4341
P P+PP S P Q P PS LP SP + P +A Q+PP+ P
Sbjct: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578
Query: 4342 GTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
+P Q P P PG ++ + L P PP
Sbjct: 579 ASPTLQAPRRPPTPG----PDTSVSGPRLTLALAPGPPP 613
Score = 67.0 bits (162), Expect = 5e-10
Identities = 148/584 (25%), Positives = 191/584 (32%), Gaps = 130/584 (22%)
Query: 4012 PGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSG 4071
PG LG L E+ +ATE P L+ G ++ PG P+++
Sbjct: 126 PGPLGQKGLRISAEETVA----RGKATEAPKR---SALSAGARRDTSGPTPGTPSPAMAR 178
Query: 4072 DSQLLLVQPQ-PQPQPSSLQLQPPLRLPGQQQQQVSLLHT------------AGGGSHGQ 4118
S+ + P+P PS+ + +PP P + S T AGGG
Sbjct: 179 RSRAAGTEVGLPRPAPSA-RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 4119 LGSGSSSEASSV-------------PHLLAQPSVSLGDQPGSMTQNLLGPQQPMLER--- 4162
SS A+ + P A PS QP L P Q R
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPS-----QPKPKGLQALRPPQVTPPRKDA 292
Query: 4163 -PMQNNTGPQP---PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQ 4218
P P P P LQS Q P + P L QL L P SP
Sbjct: 293 APALGPLSSSPLATPSPSAALQS-QAPPTLPATPHSSSLTCQLATPLPLAPP----SPSA 347
Query: 4219 QQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELG 4278
LQ L +PP P T+ L G Q P P PL
Sbjct: 348 PPSLQTL-------------PSPPATPPSQATTSL-GSPTLQATHSFLPSPPLSPL---- 389
Query: 4279 AGPRPQGPPRL--------PAPPGALSTGPVLGP---------VHP-----TPPPSSPQE 4316
A P PQ PP L P+PP + P+ P VH +PPPS P +
Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449
Query: 4317 -----PKRPSQLPS--PSSQLPTE-----AQLPPTHPGTPKPQGPTLEPPPGRVSPAAA- 4363
P P PS P SQ P Q+PP+ P +P P P+ PPP P AA
Sbjct: 450 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAP 508
Query: 4364 ---------QLADTLFSKGLGPWDPPDNLAETQKP-EQSSLVPGHLDQVNGQVVPEASQL 4413
Q L + L P Q P S+ +P P
Sbjct: 509 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
Query: 4414 SIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQ 4473
+ Q P P + Q+ +R P P TS ++GPR L L
Sbjct: 569 PLLQVPPSPPASPTLQAPRR----PPTPGPDTS----VSGPR------LTLALAPGPPPP 614
Query: 4474 LSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKP 4517
S S ++ GH S ++L+G S E AA P
Sbjct: 615 PSRSPSSTLSGPDLAGH-SSSATSTPEELRGYDSGPEGGAAASP 657
Score = 66.2 bits (160), Expect = 8e-10
Identities = 167/690 (24%), Positives = 228/690 (33%), Gaps = 118/690 (17%)
Query: 4325 SPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA 4384
+P+++ P L P PG+P+P PPP V+PAA ++ + G P LA
Sbjct: 16 TPAARAP--GLLTPRPPGSPRP------PPP--VTPAALRVLGAAGAVGRKP------LA 59
Query: 4385 ETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALG----AQSVKREANGEPI 4440
E + +P + P S + + P P A G A K + G P+
Sbjct: 60 ERAGGIGGATIPESAPRAG----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG-PV 114
Query: 4441 GAPGTSNHLLLAGPRSEAGHLLL--QKLLRAKNVQLSTGRG-SEGLRAEINGHIDSKLAG 4497
+PG ++ GP + G + + + R K + S G R + +G
Sbjct: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG-------- 166
Query: 4498 LEQKLQGTPS----NKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLK 4553
GTPS + AA + P+P + RK + +E
Sbjct: 167 ---PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA 223
Query: 4554 QLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTK 4613
++ + L PA + S P S P RG P P + SQ K
Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSS--PARSGPSARGT------PRAPAHPSQPKPK 275
Query: 4614 NNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKS 4673
+ P P PP G S L AA + L T S
Sbjct: 276 GLQALRP------PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
Query: 4674 LDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQE 4733
L A P P + +P S+ SP + +A LGS Q
Sbjct: 330 LTCQLATPLPL----------APPSPSAPPSLQTLPSPPATPPSQATT--SLGSPTL-QA 376
Query: 4734 DRALSPVIPLIPRASIPVFPDTKPYGALG-LEVPGKLPVTTWEKGKGSEVSVMLTVSAAA 4792
+ P PL P A+ P P P AL L+ P P + +S + T S A
Sbjct: 377 THSFLPSPPLSPLATPP--PQAPPALALPPLQAPPSPPASP-------PLSPLATPSPQA 427
Query: 4793 AKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDT 4852
L AV L + P P P +A P P P
Sbjct: 428 PNAL-----AVHLLQAPFSPP------PSPPVQAPFSPPASPPVSPSATP-------PSQ 469
Query: 4853 GPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPE 4912
P L +P S SP+ PP Q L QL+ PPP+
Sbjct: 470 APPSLAAPPLQVPPSPPASP--------PMSPSATPPPQAPPPLAAPPL---QLAKPPPQ 518
Query: 4913 EP----SPP----PSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
P +PP PSP A P P P LP PLA PP +P LA+ P P
Sbjct: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578
Query: 4965 ARPPEEGEDSRPPRLKKWKGVRWKRLRLLL 4994
A P + RPP V RL L L
Sbjct: 579 ASPTLQA-PRRPPTPGPDTSVSGPRLTLAL 607
Score = 64.3 bits (155), Expect = 3e-09
Identities = 164/715 (22%), Positives = 226/715 (31%), Gaps = 149/715 (20%)
Query: 4281 PRPQGPPRLPAP--PGALSTGPVLGPVHPTP-------------PPSSPQE-PKRPSQLP 4324
PRP G PR P P P AL G V P P S+P+ P R +
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86
Query: 4325 S--PSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGL--GPWDPP 4380
S P+S+ P + P GP PGR S L KGL +
Sbjct: 87 SRNPASRPPASGRGERAPPAKNTSPGPV--SSPGRAS--GTTRPGPLGQKGLRISAEETV 142
Query: 4381 DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPI 4440
T+ P++S+L G +G P ++ + R A G + G P
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGP-TPGTPSPAMARRSR----AAGTEV------GLPR 191
Query: 4441 GAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQ 4500
AP GPR GL+ + + S L
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251
Query: 4501 KLQGTPSNK-EDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQEL 4559
+ PS + A P PKPK +Q V+ +K A+ AL L
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK-------DAAPAL-----GPL 299
Query: 4560 SLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNP 4619
S PL P+ +A AP LP P + S L + P
Sbjct: 300 SSSPLATPSPSAALQSQAP-------------------PTLPATP-HSSSLTCQLATPLP 339
Query: 4620 PTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAA 4679
PPS P+ PPS+Q TP P A ++ S L+ T L+
Sbjct: 340 LAPPS---PSAPPSLQTLPSPPATP-------PSQATTSLGSP-TLQATHSFLPSPPLSP 388
Query: 4680 LPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSP 4739
L TPP + + + SP PAS P S L +P+ P+ + Q + P
Sbjct: 389 LATPPPQAPPALALPPLQAPPSP----PASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444
Query: 4740 VIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGV 4799
P+ S P P P + P L + S ++ SA
Sbjct: 445 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504
Query: 4800 MVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQ 4859
+ A L K P P++P T P + P
Sbjct: 505 L-AAPPLQLAKPP-------PQAPPALATPPLQALPSPP--------------------- 535
Query: 4860 FDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS 4919
A PG AP P+ ++L + L+ PPP+ P +
Sbjct: 536 --ASFPG-----------------QAPFSPS--------ASLPMSPLATPPPQAPPVLAA 568
Query: 4920 PLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPE------SARPKPRARPP 4968
PL P SPP P ++ P PP P P S P P P +R P
Sbjct: 569 PLLQVPPSPPASPTLQAP----RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619
Score = 57.0 bits (136), Expect = 5e-07
Identities = 102/394 (25%), Positives = 141/394 (35%), Gaps = 53/394 (13%)
Query: 4037 ATEGPSTHQGGPL-AIGTTPESMATEP-----GEVKPSLSGDSQLLLVQPQPQPQPSSLQ 4090
AT S + GP + GT+ + A+ P GE P S P P +S
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP----GPVSSPGRASGT 123
Query: 4091 LQP-PLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMT 4149
+P PL GQ+ ++S T G + S+ A A+ S G PG+ +
Sbjct: 124 TRPGPL---GQKGLRISAEETVARGKATEAPKRSALSAG------ARRDTS-GPTPGTPS 173
Query: 4150 QNLLGPQQPM-----LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGV 4204
+ + L RP + P+PP GP P+ R G
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPS-ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
Query: 4205 LAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLG 4264
+ P R LS A + + + R TP +Q P +GL +P
Sbjct: 233 GLQRPASRSLSSS------ATPLSSPARSGPSARGTPRAPAHPSQPKP-KGLQALRPPQV 285
Query: 4265 GFP----GPQTGPLQELG-AGPRP------QGPPRLPAPPGA------LSTGPVLGPVHP 4307
P P GPL A P P Q PP LPA P + L+T L P P
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345
Query: 4308 TPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLAD 4367
+ PPS P P+ PS ++ L TH P P L PP + PA A
Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA--LP 403
Query: 4368 TLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQ 4401
L + P PP + T P+ + + HL Q
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437
Score = 55.5 bits (132), Expect = 1e-06
Identities = 110/431 (25%), Positives = 145/431 (33%), Gaps = 74/431 (17%)
Query: 3997 LGPGMPAKP--LQHFSSPGALGPTLLLTGKEQNTVD--------PAVSSEATEGPSTHQG 4046
L P P+ P LQ SP A P+ T T+ P +S AT P
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA--- 396
Query: 4047 GPLAIGTTPESMATEPGEVKPSLSGDSQLL-LVQPQPQPQPSSLQ---LQPPLRLPGQQQ 4102
P ++A P + PS L L P PQ P++L LQ P P
Sbjct: 397 --------PPALALPPLQAPPSPPASPPLSPLATPSPQA-PNALAVHLLQAPFSPPPSPP 447
Query: 4103 QQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLER 4162
Q A S S++ S P LA P + + P + P P
Sbjct: 448 VQAPFSPPASPPV-----SPSATPPSQAPPSLAAPPLQVPPSPPASP-----PMSPSATP 497
Query: 4163 PMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQL 4222
P Q PP P LQ + P L+A L A P SP +
Sbjct: 498 PPQ----APPPLAAPPLQLAKPPPQAPPALATPPLQA-LPSPPASFPGQAPFSPSASLPM 552
Query: 4223 QALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF--------PGPQT--- 4271
L TPP Q P +PL + P PGP T
Sbjct: 553 SPLA-------------TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 599
Query: 4272 GPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS--PSSQ 4329
GP L P P PP P + +GP L H + S+P+E + P ++
Sbjct: 600 GPRLTLALAPGPPPPPS--RSPSSTLSGPDLAG-HSSSATSTPEELRGYDSGPEGGAAAS 656
Query: 4330 LPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389
P +A+L HP +GP PP A + G G D + ET+ P
Sbjct: 657 PPPDAELAACHPAAWS-RGPA---PPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 712
Query: 4390 EQSSLVPGHLD 4400
E ++ PG LD
Sbjct: 713 ESATPAPGALD 723
Score = 38.9 bits (89), Expect = 0.14
Identities = 95/363 (26%), Positives = 116/363 (31%), Gaps = 70/363 (19%)
Query: 3076 ANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASV-------LPEVKPKVEEGGRH 3128
A E +R AL G GP P A A R A P +P+ G
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206
Query: 3129 PSPCQFTIATPKVEPAPAAN---SLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASF 3185
S + + EP+PAA S G GL+ SR P SS + A
Sbjct: 207 KSVSSASEHST-TEPSPAARRRPSAGGGLQ----RPASRSLSSSATPLSSPARSGPSAR- 260
Query: 3186 GATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASEL 3245
T PAH P P L +T P AA L + SS +A+
Sbjct: 261 -GTPRAPAHPSQPKPKGLQA---------LRPPQVTPPRKDAAPA--LGPLSSSPLATPS 308
Query: 3246 PLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSL-LSAPGPAQAMSLPHEGSSP 3304
P LQ + + P Q L L+ P P+ SL S P
Sbjct: 309 P----------SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358
Query: 3305 SLAGSQQQLSLG--LAGARQPGLPQPLM-------PTQPPAHALQQRLAP---------- 3345
+ SQ SLG A LP P + P PPA AL AP
Sbjct: 359 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 418
Query: 3346 SMAMVSNQGHMLSGQHGGQAGLVPQQS-----------SQPVL-SQKPMGTMPPSMCMKP 3393
+A S Q H QA P S S PV S P PPS+ P
Sbjct: 419 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 478
Query: 3394 QQL 3396
Q+
Sbjct: 479 LQV 481
Score = 37.7 bits (86), Expect = 0.32
Identities = 73/298 (24%), Positives = 96/298 (32%), Gaps = 51/298 (17%)
Query: 4031 PAVSSEAT---EGPSTHQGGPLAIGTTPESM------ATEPGEVKPSLSGDSQLLLVQPQ 4081
P VS AT + P + PL + +P + AT P + P L+ L L +P
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP-LQLAKPP 516
Query: 4082 PQPQPS----SLQL--QPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA 4135
PQ P+ LQ PP PGQ S S ++ P +LA
Sbjct: 517 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM---------SPLATPPPQAPPVLA 567
Query: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVG 4195
P + + P P P L+ P + PP PGP + + P
Sbjct: 568 APLLQVPPSP---------PASPTLQAPRR------PPTPGPDTSVSGPRLTLALAPGPP 612
Query: 4196 QLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQG 4255
++ P L S + L + A PP E P
Sbjct: 613 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA-CHPAAW 671
Query: 4256 LLGCQPQLG--GFPG------PQTGPLQELGAGP--RPQGPPRLPAPPGALSTGPVLG 4303
G P L G PG P TGP G +GP PGAL GP G
Sbjct: 672 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 729
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 146 bits (369), Expect = 5e-34
Identities = 153/622 (24%), Positives = 244/622 (39%), Gaps = 77/622 (12%)
Query: 362 AEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGK 421
AE T + +P EP T EP S PKEP P ++ P
Sbjct: 201 AETTTKGPALTTPKEPTPTTPKEP----------------ASTTPKEPTPTTIKSAPTTP 244
Query: 422 AGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTS---PPPEASRLSPPPEELPASP 478
AP + P +E + P E +PT+ P P ++ +P + PA
Sbjct: 245 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 304
Query: 479 LPEALHLSRPLEESPLSP--PPEESPLSPPP---ESSPFSPLEESPLSPPEESPPSPALE 533
P+ + P E +P +P P +P P P E +P +P E +P +P + +P +P
Sbjct: 305 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 364
Query: 534 TPLSP-PPEASPLSPPFEESPLSPPP---EELPTS---PPPEASRLSPPPEESPMSPPPE 586
P +P P + P +P P P + PT+ P P ++ +P + P SP
Sbjct: 365 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTT 423
Query: 587 ESPMSPPPEASRLFPPFEESPLSP--PPEESPLSPPPEASRLSPP--PEDSPMSPPPEES 642
+ P P+ P + +P +P P +P P P ++ P P++ + P E +
Sbjct: 424 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483
Query: 643 PMSP----PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP------PPEASRLSPP 692
P +P P +L+P PEE + P E +PT+P P+A+ + P
Sbjct: 484 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 543
Query: 693 PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL 752
E +PT+P PA P++ + P E +P P P + P +P L
Sbjct: 544 KEPAPTTP---KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL-KEPAPTTPKKPAPKEL 599
Query: 753 SPRPEEPHLSPQAEEP-HLSPQ------PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805
+P + S ++P +P+ P+EP E +P+ P +P
Sbjct: 600 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP---- 655
Query: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
+P T + P P+E L+P + S S++P P+E+ +P K P P+
Sbjct: 656 -APTTPK---KPAPKE--LAPTTTKGPTSTTSDKPA-PTTPKET--APTTPKEPAPTTPK 706
Query: 866 KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSL 925
KP + P P + P + + P S P E P P+ L SP EP
Sbjct: 707 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPK-EPG- 763
Query: 926 SPQLMPPDPLPPPLSPIITAAA 947
+P P P +T A
Sbjct: 764 ----VPTTKTPAATKPEMTTTA 781
Score = 144 bits (363), Expect = 2e-33
Identities = 146/593 (24%), Positives = 226/593 (38%), Gaps = 67/593 (11%)
Query: 416 AKPLGKAGVQLE-PQLEAPLNEEMPLLP--PPEESPLSPPPEE------SPTSPPPEASR 466
AKP KA + P L P E P P P +P P P +P P P ++
Sbjct: 195 AKPTPKAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 253
Query: 467 LSPPPEELPASPLPEALHLSRPLEESPLS---PPPEESPLSP--PPESSPFSPLEESPLS 521
+P + PA + + P E +P + P P + +P P E +P +P + +P +
Sbjct: 254 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 313
Query: 522 PPEESPPSPALETPLSPPPEASPLSPPFEESPLSP----PPEELPTSPPPEASRLSPPPE 577
P E +P +P TP +P A P +P P P + PT+P A P
Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373
Query: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP--PPEASRLSP----PPE 631
+ P +P P P ++ P + P + +P +P P + P P E
Sbjct: 374 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 433
Query: 632 DSPMSP--PPEESPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPEESPTSP----P 683
+P +P P +P P P + P P ++ P P+E + P E +PT+P P
Sbjct: 434 PAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 492
Query: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP------LPEEPQLCPR 737
+L+P + P PE+ A PE+ + P E +P P P+EP P
Sbjct: 493 TTPEKLAPTTPEKPAPTTPEEL-APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP--APT 549
Query: 738 SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797
+ P+EP + E +P+ P +P P++P +P+ P
Sbjct: 550 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP----TTPKKP--APKELAPTT 603
Query: 798 SPQPEELHL---SPQTEEPHLSPVPEEPCLSPQPEESHLSP--------QSEEPCLSPRP 846
+ +P +P T + P+EP + E + +P + P +P
Sbjct: 604 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 663
Query: 847 EESHLSPELEKPPLSPRPEKP----PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902
L+P K P S +KP P+E E P P P+ +P P SE
Sbjct: 664 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE 722
Query: 903 PGEPPLSPLPEELPLSP-SGEPSLSPQLMPPDPLPPPLSP-IITAAAPPALSP 953
P + P + SP P LS + P P P + T P A P
Sbjct: 723 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 775
Score = 133 bits (334), Expect = 6e-30
Identities = 157/658 (23%), Positives = 247/658 (37%), Gaps = 124/658 (18%)
Query: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG-KAGVQLEPQLE 431
+P EP T EP T PKEP P E P K P+
Sbjct: 313 TPKEPAPTTPKEP----------------TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 356
Query: 432 APLNEEMPLLPPPEESPLSPPPEESPTSPP---PEASRLSPPPEELPASPLPEALHLSRP 488
AP + P P+E + E SPT+P P ++ +P + PA P + P
Sbjct: 357 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTP 415
Query: 489 LEESPLSPP------PEESPLSPPPESSPFSPLEESPLSPPEESPPS---PALETPLSPP 539
E SP + P+E + P + +P +P E +P +P E +P + PA TP P
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475
Query: 540 PEASPLSPPFEESPLSPP-PEEL-PTSP----PPEASRLSPPPEESPMSPPPEESPMSPP 593
P + P L+P PE+L PT+P P L+P E P PEE P
Sbjct: 476 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE-PAPTT 534
Query: 594 PEASRLFPPFEESPLSP-------PPEESPLSPPPEA---------SRLSPPPEDSPMSP 637
P+A+ P E +P +P P E +P +P A + L P +P P
Sbjct: 535 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 594
Query: 638 PPEE---SPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPEESPTSPPPEA-SRLSP 691
P+E + P + P P + + P P+E + P E +PT+P A + L
Sbjct: 595 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 654
Query: 692 PPEDSPTSPPPE---------------DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736
P +P P P+ D PA P+++ + P E +P P P P
Sbjct: 655 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT-P 713
Query: 737 RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL----SPQA 792
+ P S P + P H SP P LS +P L P+EP + +P A
Sbjct: 714 ETPPPTTS-EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 772
Query: 793 EGPHLSPQPEE------LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE------- 839
P ++ ++ L +P+T E + + ES ++ + +
Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 832
Query: 840 ------------PCLSPR----------------PEESHLSPE--LEKPPLSPRPEKPPE 869
L+P+ PEE+ + +P+P+KP +
Sbjct: 833 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 892
Query: 870 EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927
P + + ++ P +P +P + + P P S + E + L + P+ +P
Sbjct: 893 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAM-LQTTTRPNQTP 949
Score = 130 bits (327), Expect = 4e-29
Identities = 169/750 (22%), Positives = 249/750 (33%), Gaps = 89/750 (11%)
Query: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPE------------ESPPSPALETPLSPPP 540
P++P P P S + + + +E+ + E + + A ET
Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182
Query: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP--PPEESPMSPPPEASR 598
A L+P + P E T P L+ P E +P +P P +P P P +
Sbjct: 183 SAKDLAPTSKVLAKPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTPTTIK 238
Query: 599 LFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV 658
P + P + +P +P A + P + P + P P ++ +P
Sbjct: 239 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 298
Query: 659 VSRLSPPPEESPLSPPPEESPTSP--PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM 716
P++ + P E +PT+P P + P P +P PA P+
Sbjct: 299 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 717 SLPLEESPLLP--------------LPEEPQLCPRSEGPHLS--PRPEEPHLSP-RPEEP 759
+ P E +P P P+EP P + P P +P P+EP
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 418
Query: 760 HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819
SP + P+EP + +P+ P +P +P T + P
Sbjct: 419 --SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP-----APTTTKKPAPTTP 471
Query: 820 EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP-PLSPRPEKP--PEEPGQCPA 876
+EP + E + +P+ L+P E EKP P +P P PEEP
Sbjct: 472 KEPAPTTPKETAPTTPKK----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 527
Query: 877 PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
E P P P+ EPA + P EP + E P +P +P+ P L
Sbjct: 528 EEPAPTTPKAAAPNTPK---EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 584
Query: 937 PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV 996
P AP L+P E P D P +P A T EP
Sbjct: 585 EPAPTTPKKPAPKELAPTTTKE-PTSTTCDK-----------PAPTTPKGTAPTTPKEPA 632
Query: 997 PPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLS 1056
P P+P +P G A L EP P L P + P + P+P +
Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK----GPTSTTSDKPAPTT 688
Query: 1057 PIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116
P E T K P P P TS ++S P + P S
Sbjct: 689 PKETAPTTPKEP---APTTPKKPAPTTPETPPPTTS-------EVSTPTTTKEPTTIHKS 738
Query: 1117 GLGEDTAPLDGIDAP----GSQPEPG----QTPGSLASELKGSPVLLDPEELAPVTPMEV 1168
E T L P S EPG +TP + E+ + E TP
Sbjct: 739 P-DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 797
Query: 1169 YPECKQTAGQGSPCEEQEEPRAPVAPTPPT 1198
K T + E+ E + T T
Sbjct: 798 TAAPKMTKETATTTEKTTESKITATTTQVT 827
Score = 92.8 bits (229), Expect = 8e-18
Identities = 135/583 (23%), Positives = 200/583 (34%), Gaps = 72/583 (12%)
Query: 670 PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
P++P P P S + + L+ E + + + + + +E+ +
Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182
Query: 730 EEPQLCPRSEG-PHLSPRPEEPHLSPR---PEEPHLSPQAEEPHLSPQPEEPCLCAVPEE 785
L P S+ +P+ E P P+EP +P + S P+EP +
Sbjct: 183 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP--TPTTPKEPASTTPKEPTPTTIKSA 240
Query: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS-- 843
P + P P +P T P+EP + E + +P+ P +
Sbjct: 241 PTTPKE-------PAPTTTKSAPTT--------PKEPAPTTTKEPAPTTPKEPAPTTTKE 285
Query: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL-SPLLGEPALSE 902
P P + +P K P P+KP + PAP P P P P +P EPA +
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPTPTTPKEPAPTTKEPAPTT 344
Query: 903 PGEP----PLSPLP----EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL--- 951
P EP P P P E P +P EP+ + P P +P T +AP
Sbjct: 345 PKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 403
Query: 952 SPLGELEYPFGAKGDSDPESPLAAPILE---TPISPPPEANCTDPEPVPPMILPPSPGSP 1008
+P P K S + AP P +P A T EP P P+P +
Sbjct: 404 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463
Query: 1009 VGPASPILMEPLPP---QCSPLLQHSLVPQNSPPSQCSPPALPL-SVPSPLSPIGKVVGV 1064
PA EP P + +P L P + P P + P L+P
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523
Query: 1065 SDEAELHEMETEKVSEPECPALEPSATSPL-PSPMGDLSCPAPSPAPALDDFSGLGEDTA 1123
E T K + P P EP+ T+P P+P + P+P + + TA
Sbjct: 524 PTTPEEPAPTTPKAAAPNTPK-EPAPTTPKEPAPT---TPKEPAPTTPKETAPTTPKGTA 579
Query: 1124 PLDGID--------------APGSQPEPGQT---------PGSLASELKGSPVLLDPEEL 1160
P + AP + EP T P A P P+E
Sbjct: 580 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP 639
Query: 1161 APVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSD 1203
AP TP P + +P + + AP PT SD
Sbjct: 640 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 682
Score = 91.3 bits (225), Expect = 2e-17
Identities = 134/572 (23%), Positives = 197/572 (34%), Gaps = 63/572 (11%)
Query: 2108 PQPGALGSPPPAA---APTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDS---PGELFL 2161
P P + S P APT +PTTP + + P P P + P
Sbjct: 232 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 291
Query: 2162 KLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAG 2221
K P P + P AP P EP PT P P+PT P +P + P
Sbjct: 292 KSAPTTPKEPAPTTPKKPAPTTPKEP-----APTTPKEPTPT-TPKEP--APTTKEPAPT 343
Query: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGES 2281
P E T P P P+TP K P+ P+ P K P P +
Sbjct: 344 TPKEPAPTAPKKP--APTTP----KEPAPT-----TPKEPAPTTTKEPSPTTPKEPAPTT 392
Query: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTP-RASQVEP 2340
K+ +E A + + P SP++ K P AP TP + + P
Sbjct: 393 TKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP----APTTPKKPAPTTP 447
Query: 2341 QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP--PPESCCAL 2398
+ P P+EP P P+P T P P TP+ P P +
Sbjct: 448 KEPA-PTTPKEPAPTTTKKPAP------------TTPKEPAPTTPKETAPTTPKKLTPTT 494
Query: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP-PSRP 2457
P + P+ P P +P+ + + +P P P + E P+P TP+ +P+ P P+ P
Sbjct: 495 PEKLAPTTPEKPAPTTPE-ELAPTTPEEPTPTTPEE--PAPTTPKAAAPNTPKEPAPTTP 551
Query: 2458 QSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPN 2517
+ P P K P P P+ A T+ G P L P P
Sbjct: 552 KEPAPTTP--KEPAPTTPK------ETAPTT-PKGTAPTTLKEPAPTTPKKPAPKELAPT 602
Query: 2518 FVRSP-GTGAFVGTPSPMRFTFPQAVGEPS-LKPPVPQPGLPPPHGINSHFGPGPTLGKP 2575
+ P T P+ + T P EP+ P P P P + P PT K
Sbjct: 603 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 662
Query: 2576 QSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQR 2635
+ T P+ + + +T + + + P+ P P + P +
Sbjct: 663 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-- 720
Query: 2636 SGITSPVEKREDPGTGMGSSLATAELPGTQDP 2667
S +++P +E +T EL P
Sbjct: 721 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 752
Score = 63.5 bits (153), Expect = 5e-09
Identities = 91/385 (23%), Positives = 134/385 (34%), Gaps = 57/385 (14%)
Query: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQV 2167
P+ A +P A T +PTTP + + P P P +P E P
Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET----APTT 486
Query: 2168 PAQVPSQDPFGLAPAYPLEPRFPTAP----PTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223
P ++ P LAP P +P PT P PT P P+PT P +P A + P A P
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPA-PTTPEELAPTTPEEPTPT-TPEEP----APTTPKAAAP 540
Query: 2224 GEFHTTPPGTPRHQ-PSTPDPFLKPRCPSLDNLAVPESP-GVGGGKASEPLLSPPPFGES 2281
P TP+ P+TP K P+ P +P G EP + P
Sbjct: 541 NTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596
Query: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ 2341
++ +E +++ P +P++ K P AP TP+ +
Sbjct: 597 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP----APTTPKGTAPTTL 652
Query: 2342 SPGLGLRPQEPPPAQAL---------------APSPPSH--PDIFRPGSYTDPYAQPPLT 2384
P++P P + AP+ P P + + T P P T
Sbjct: 653 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 712
Query: 2385 PRPQPPPPESCCALP-----PRSLPSDPFSRVP---ASPQSQSSSQSPLTPRPLSAEAFC 2436
P PPP S + P P ++ P P A P ++ SP P
Sbjct: 713 PE-TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG-------V 764
Query: 2437 PSPVTPRFQSPDPYSRPPSRPQSRD 2461
P+ TP P+ + + RD
Sbjct: 765 PTTKTPAATKPEMTTTAKDKTTERD 789
Score = 53.9 bits (128), Expect = 4e-06
Identities = 94/455 (20%), Positives = 143/455 (31%), Gaps = 52/455 (11%)
Query: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPL-LSPPPFGESRKALEVKKEE 2291
TP+ + +T P L P P+ P K P + P A K
Sbjct: 198 TPKAETTTKGPALTT--PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS- 254
Query: 2292 LGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE 2351
++P P +P++ K P AP T +++ P+ P P++
Sbjct: 255 -APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP----APTTTKSAPTTPKEPA-PTTPKK 308
Query: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPR-PQPPPPESCCALPPRSLPSDPFSR 2410
P P P+P T P P TP+ P P E P P+ P
Sbjct: 309 PAPTTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 356
Query: 2411 VPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP 2470
P +P+ + + +P P P + + PSP TP+ +P P+ + P P
Sbjct: 357 APTTPKEPAPT-TPKEPAPTTTKE--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413
Query: 2471 RPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP-PNFVRSPG------ 2523
P+ P T PA + A +P P + P
Sbjct: 414 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 473
Query: 2524 ------TGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTL-GKPQ 2576
TP + T P+ + + P P P P + P PT +P
Sbjct: 474 PAPTTPKETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEEPA 531
Query: 2577 STNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP----PPAPDGSLPYLSHGA 2632
T A N +P P+ + E +P P P P P G+ P
Sbjct: 532 PTTPKAAAPN-----TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 586
Query: 2633 SQRSGITSPVEKREDPGTGMGSSLATAELPGTQDP 2667
+ + P K P T + T + P P
Sbjct: 587 APTTP-KKPAPKELAPTTTKEPTSTTCDKPAPTTP 620
Score = 49.3 bits (116), Expect = 1e-04
Identities = 83/387 (21%), Positives = 117/387 (30%), Gaps = 50/387 (12%)
Query: 4601 PTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARD 4660
PT P S TK P P+ P P K TP E K A
Sbjct: 412 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 471
Query: 4661 SERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPE---SILGE 4717
E A E PT P +P+ + P + E + E
Sbjct: 472 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEE 529
Query: 4718 EAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFP-DTKPYGALGLEVPGKLPVTTWEK 4776
AP P + +E +P P P + P P T P G P T E
Sbjct: 530 PAPTTPKAAAPNTPKEP---APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 586
Query: 4777 GKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAE 4836
T A K L + K P S P GT P +
Sbjct: 587 AP-------TTPKKPAPKELAPT--------TTKEPTSTTCDKPAPTTPKGTAPTTPKEP 631
Query: 4837 GPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSL-----LKQESPAPEPPTQ 4891
P ++ T P LK+ P +L + + PAP P
Sbjct: 632 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-- 689
Query: 4892 HSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPS--P 4949
++ + P+EP+ P +P P+P +P T P PT P + P
Sbjct: 690 ------------KETAPTTPKEPA-PTTPKKPAPTTPETPP----PTTSEVSTPTTTKEP 732
Query: 4950 LPLASSPESARPKPRARPPEEGEDSRP 4976
+ SP+ + P+ A P + ++ P
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSP 759
Score = 47.0 bits (110), Expect = 5e-04
Identities = 82/383 (21%), Positives = 115/383 (30%), Gaps = 35/383 (9%)
Query: 4612 TKNNLSNPPTPPSSLPPTPPPSVQQ--KMVNGVTPSEELGEHPKDAASARDSERALRDTS 4669
T + + PT P PT S K T E PK+ A E A T
Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 292
Query: 4670 EVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGR 4729
+ A PT P E + + P E AP P +
Sbjct: 293 SAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 351
Query: 4730 WEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPG-----KLPVTTWEKGKGSEVSV 4784
++ +P P P TK + P P TT E + S
Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411
Query: 4785 MLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKG 4844
T + + + P P+ PA T PK+ P +K
Sbjct: 412 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKE---PAPTTTKKP 466
Query: 4845 LEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVR 4904
+ P K+ P + + L+ E PAP P
Sbjct: 467 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP--------------E 512
Query: 4905 QLSAPPPEEPSPP----PSPLAPSPASP--PTEPLVELPTEPLAEPPVPSPLPLASSPES 4958
+L+ PEEP+P P+P P A+P P EP P EP P P + E+
Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP--APTTPKEPAPTTPKET 570
Query: 4959 ARPKPRARPPEEGEDSRPPRLKK 4981
A P+ P ++ P KK
Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKK 593
Score = 40.8 bits (94), Expect = 0.038
Identities = 112/590 (18%), Positives = 185/590 (31%), Gaps = 66/590 (11%)
Query: 3999 PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESM 4058
P P KP ++P PT T KE P + T+ P+ A +
Sbjct: 303 PTTPKKPAP--TTPKEPAPT---TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357
Query: 4059 ATEPGEVKPSLSGD-SQLLLVQPQP----QPQPSSLQLQPPLRLPGQQQQQVSLLHTAGG 4113
T P E P+ + + +P P +P P++ + P T
Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT---------------TTKE 402
Query: 4114 GSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPP 4173
+ S ++ P +P+ + +P T P P P T P+ P
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP----TTPKEP 458
Query: 4174 KPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQ 4233
P + P PT + A L+P ++ A +L
Sbjct: 459 APTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEELAP 516
Query: 4234 SQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP--PRLPA 4291
+ TP E T+P P P P T P + P+ P P+ A
Sbjct: 517 TTPEEPTPTTPEEPAPTTPK----AAAPNTPKEPAPTT-PKEPAPTTPKEPAPTTPKETA 571
Query: 4292 PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTL 4351
P T P P P++P++P P +L +++ PT P TPK PT
Sbjct: 572 PTTPKGTAPT---TLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627
Query: 4352 EPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAET-QKPEQSSLVPGHLDQVNGQVVPEA 4410
P +P + A T KG P + T +KP L P +
Sbjct: 628 PKEPAPTTP--KEPAPTT-PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684
Query: 4411 SQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAK 4470
+ + K+ P + K+ A P P T++ + E
Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE------------- 731
Query: 4471 NVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPK-----RV 4525
+ + + E++ K K G P+ K AA + +T K R
Sbjct: 732 --PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 789
Query: 4526 QKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSL 4575
+ + ++ K+ KE + ++ + + T T F +
Sbjct: 790 LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 839
Score = 40.8 bits (94), Expect = 0.038
Identities = 84/369 (22%), Positives = 108/369 (29%), Gaps = 49/369 (13%)
Query: 4620 PTPPSSLPPTP--PPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLL 4677
PT S P TP P K TP E PK A E A E
Sbjct: 405 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 464
Query: 4678 AALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRAL 4737
PT P E+ + P + P ++PE + AP P + +E L
Sbjct: 465 KPAPTTPKEPAPTTPKETAPTT--PKKLTP-TTPEKL----APTTPEKPAPTTPEE---L 514
Query: 4738 SPVIPLIPRASIPVFP-DTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNL 4796
+P P P + P P T P A P T E + T A
Sbjct: 515 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 574
Query: 4797 NGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDW 4856
L P + P+ PA P + +K T P
Sbjct: 575 PKGTAPTT--LKEPAPTT-----PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627
Query: 4857 LKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSP 4916
K+ P + PAP P + T L P P P
Sbjct: 628 PKEPAPTTP----------------KEPAPTTPKGTAPT---------TLKEPAPTTPKK 662
Query: 4917 P-PSPLAPSPASPPTEPLVE--LPTEPLAEPPVPSPLPLASSPESARP-KPRARPPEEGE 4972
P P LAP+ PT + PT P P P ++P+ P P PP E
Sbjct: 663 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 722
Query: 4973 DSRPPRLKK 4981
S P K+
Sbjct: 723 VSTPTTTKE 731
Score = 38.1 bits (87), Expect = 0.24
Identities = 34/123 (27%), Positives = 44/123 (35%), Gaps = 13/123 (10%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP--PRLPAPPGALS 4297
TP P T P P P P T P + P+ P P+ P P +
Sbjct: 274 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPTP----T 328
Query: 4298 TGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR 4357
T P P P++P+EP + P PT + P P TPK PT P
Sbjct: 329 TPKEPAPTTKEPAPTTPKEPAPTA----PKKPAPTTPKEPA--PTTPKEPAPTTTKEPSP 382
Query: 4358 VSP 4360
+P
Sbjct: 383 TTP 385
Score = 35.8 bits (81), Expect = 1.2
Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 3/108 (2%)
Query: 4877 SLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP-PEEPSPPPSPLAP-SPASP-PTEPL 4933
+L + P P P + + T SAP P+EP+P + AP +P P PT
Sbjct: 209 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 268
Query: 4934 VELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKK 4981
PT P P + P ++ +SA P+ P + P K+
Sbjct: 269 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316
Score = 34.7 bits (78), Expect = 2.7
Identities = 36/126 (28%), Positives = 44/126 (34%), Gaps = 8/126 (6%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPP--RLPAPPGALS 4297
TP T P + P P P T + P+ P + PAP
Sbjct: 220 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT--TKSAPTTPKEPAPTTTKEPAPTTPKE 277
Query: 4298 TGPVLGPVH-PTPPPSSPQEPKRPSQLPSPSSQLPTEAQLP-PTHPGTPKPQGPTLEPPP 4355
P PT S+P PK P+ +P PT + P PT P P P P EP P
Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPTPTTPK-EPAP 335
Query: 4356 GRVSPA 4361
PA
Sbjct: 336 TTKEPA 341
Score = 33.9 bits (76), Expect = 4.6
Identities = 44/198 (22%), Positives = 68/198 (34%), Gaps = 11/198 (5%)
Query: 4165 QNNTGPQP-PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQ 4223
+N T +P PKP V ++G GL T ++ +P++ P +
Sbjct: 71 KNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSL 130
Query: 4224 ALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRP 4283
+ S V + + T T+ Q + + +T +++ A
Sbjct: 131 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTS--AKETQSIEKTSAKDLA 188
Query: 4284 QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT 4343
L P T GP TP +P PK P+ +P PT + PT P
Sbjct: 189 PTSKVLAKPTPKAET-TTKGPALTTPKEPTPTTPKEPAS-TTPKEPTPTTIKSAPTTPKE 246
Query: 4344 PKP----QGPTL--EPPP 4355
P P PT EP P
Sbjct: 247 PAPTTTKSAPTTPKEPAP 264
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 146 bits (369), Expect = 5e-34
Identities = 153/622 (24%), Positives = 244/622 (39%), Gaps = 77/622 (12%)
Query: 362 AEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGK 421
AE T + +P EP T EP S PKEP P ++ P
Sbjct: 242 AETTTKGPALTTPKEPTPTTPKEP----------------ASTTPKEPTPTTIKSAPTTP 285
Query: 422 AGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTS---PPPEASRLSPPPEELPASP 478
AP + P +E + P E +PT+ P P ++ +P + PA
Sbjct: 286 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 345
Query: 479 LPEALHLSRPLEESPLSP--PPEESPLSPPP---ESSPFSPLEESPLSPPEESPPSPALE 533
P+ + P E +P +P P +P P P E +P +P E +P +P + +P +P
Sbjct: 346 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 405
Query: 534 TPLSP-PPEASPLSPPFEESPLSPPP---EELPTS---PPPEASRLSPPPEESPMSPPPE 586
P +P P + P +P P P + PT+ P P ++ +P + P SP
Sbjct: 406 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTT 464
Query: 587 ESPMSPPPEASRLFPPFEESPLSP--PPEESPLSPPPEASRLSPP--PEDSPMSPPPEES 642
+ P P+ P + +P +P P +P P P ++ P P++ + P E +
Sbjct: 465 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524
Query: 643 PMSP----PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP------PPEASRLSPP 692
P +P P +L+P PEE + P E +PT+P P+A+ + P
Sbjct: 525 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 584
Query: 693 PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL 752
E +PT+P PA P++ + P E +P P P + P +P L
Sbjct: 585 KEPAPTTP---KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL-KEPAPTTPKKPAPKEL 640
Query: 753 SPRPEEPHLSPQAEEP-HLSPQ------PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805
+P + S ++P +P+ P+EP E +P+ P +P
Sbjct: 641 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP---- 696
Query: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
+P T + P P+E L+P + S S++P P+E+ +P K P P+
Sbjct: 697 -APTTPK---KPAPKE--LAPTTTKGPTSTTSDKPA-PTTPKET--APTTPKEPAPTTPK 747
Query: 866 KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSL 925
KP + P P + P + + P S P E P P+ L SP EP
Sbjct: 748 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPK-EPG- 804
Query: 926 SPQLMPPDPLPPPLSPIITAAA 947
+P P P +T A
Sbjct: 805 ----VPTTKTPAATKPEMTTTA 822
Score = 144 bits (363), Expect = 2e-33
Identities = 146/593 (24%), Positives = 226/593 (38%), Gaps = 67/593 (11%)
Query: 416 AKPLGKAGVQLE-PQLEAPLNEEMPLLP--PPEESPLSPPPEE------SPTSPPPEASR 466
AKP KA + P L P E P P P +P P P +P P P ++
Sbjct: 236 AKPTPKAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 294
Query: 467 LSPPPEELPASPLPEALHLSRPLEESPLS---PPPEESPLSP--PPESSPFSPLEESPLS 521
+P + PA + + P E +P + P P + +P P E +P +P + +P +
Sbjct: 295 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 354
Query: 522 PPEESPPSPALETPLSPPPEASPLSPPFEESPLSP----PPEELPTSPPPEASRLSPPPE 577
P E +P +P TP +P A P +P P P + PT+P A P
Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414
Query: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP--PPEASRLSP----PPE 631
+ P +P P P ++ P + P + +P +P P + P P E
Sbjct: 415 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 474
Query: 632 DSPMSP--PPEESPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPEESPTSP----P 683
+P +P P +P P P + P P ++ P P+E + P E +PT+P P
Sbjct: 475 PAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 533
Query: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP------LPEEPQLCPR 737
+L+P + P PE+ A PE+ + P E +P P P+EP P
Sbjct: 534 TTPEKLAPTTPEKPAPTTPEEL-APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP--APT 590
Query: 738 SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797
+ P+EP + E +P+ P +P P++P +P+ P
Sbjct: 591 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP----TTPKKP--APKELAPTT 644
Query: 798 SPQPEELHL---SPQTEEPHLSPVPEEPCLSPQPEESHLSP--------QSEEPCLSPRP 846
+ +P +P T + P+EP + E + +P + P +P
Sbjct: 645 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 704
Query: 847 EESHLSPELEKPPLSPRPEKP----PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902
L+P K P S +KP P+E E P P P+ +P P SE
Sbjct: 705 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE 763
Query: 903 PGEPPLSPLPEELPLSP-SGEPSLSPQLMPPDPLPPPLSP-IITAAAPPALSP 953
P + P + SP P LS + P P P + T P A P
Sbjct: 764 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 816
Score = 133 bits (334), Expect = 6e-30
Identities = 157/658 (23%), Positives = 247/658 (37%), Gaps = 124/658 (18%)
Query: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG-KAGVQLEPQLE 431
+P EP T EP T PKEP P E P K P+
Sbjct: 354 TPKEPAPTTPKEP----------------TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 397
Query: 432 APLNEEMPLLPPPEESPLSPPPEESPTSPP---PEASRLSPPPEELPASPLPEALHLSRP 488
AP + P P+E + E SPT+P P ++ +P + PA P + P
Sbjct: 398 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTP 456
Query: 489 LEESPLSPP------PEESPLSPPPESSPFSPLEESPLSPPEESPPS---PALETPLSPP 539
E SP + P+E + P + +P +P E +P +P E +P + PA TP P
Sbjct: 457 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 516
Query: 540 PEASPLSPPFEESPLSPP-PEEL-PTSP----PPEASRLSPPPEESPMSPPPEESPMSPP 593
P + P L+P PE+L PT+P P L+P E P PEE P
Sbjct: 517 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE-PAPTT 575
Query: 594 PEASRLFPPFEESPLSP-------PPEESPLSPPPEA---------SRLSPPPEDSPMSP 637
P+A+ P E +P +P P E +P +P A + L P +P P
Sbjct: 576 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 635
Query: 638 PPEE---SPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPEESPTSPPPEA-SRLSP 691
P+E + P + P P + + P P+E + P E +PT+P A + L
Sbjct: 636 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 695
Query: 692 PPEDSPTSPPPE---------------DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736
P +P P P+ D PA P+++ + P E +P P P P
Sbjct: 696 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT-P 754
Query: 737 RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL----SPQA 792
+ P S P + P H SP P LS +P L P+EP + +P A
Sbjct: 755 ETPPPTTS-EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 813
Query: 793 EGPHLSPQPEE------LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE------- 839
P ++ ++ L +P+T E + + ES ++ + +
Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 873
Query: 840 ------------PCLSPR----------------PEESHLSPE--LEKPPLSPRPEKPPE 869
L+P+ PEE+ + +P+P+KP +
Sbjct: 874 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 933
Query: 870 EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927
P + + ++ P +P +P + + P P S + E + L + P+ +P
Sbjct: 934 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAM-LQTTTRPNQTP 990
Score = 130 bits (327), Expect = 4e-29
Identities = 169/750 (22%), Positives = 249/750 (33%), Gaps = 89/750 (11%)
Query: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPE------------ESPPSPALETPLSPPP 540
P++P P P S + + + +E+ + E + + A ET
Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 223
Query: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP--PPEESPMSPPPEASR 598
A L+P + P E T P L+ P E +P +P P +P P P +
Sbjct: 224 SAKDLAPTSKVLAKPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTPTTIK 279
Query: 599 LFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV 658
P + P + +P +P A + P + P + P P ++ +P
Sbjct: 280 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 339
Query: 659 VSRLSPPPEESPLSPPPEESPTSP--PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM 716
P++ + P E +PT+P P + P P +P PA P+
Sbjct: 340 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 717 SLPLEESPLLP--------------LPEEPQLCPRSEGPHLS--PRPEEPHLSP-RPEEP 759
+ P E +P P P+EP P + P P +P P+EP
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 459
Query: 760 HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819
SP + P+EP + +P+ P +P +P T + P
Sbjct: 460 --SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP-----APTTTKKPAPTTP 512
Query: 820 EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP-PLSPRPEKP--PEEPGQCPA 876
+EP + E + +P+ L+P E EKP P +P P PEEP
Sbjct: 513 KEPAPTTPKETAPTTPKK----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 568
Query: 877 PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
E P P P+ EPA + P EP + E P +P +P+ P L
Sbjct: 569 EEPAPTTPKAAAPNTPK---EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 625
Query: 937 PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV 996
P AP L+P E P D P +P A T EP
Sbjct: 626 EPAPTTPKKPAPKELAPTTTKE-PTSTTCDK-----------PAPTTPKGTAPTTPKEPA 673
Query: 997 PPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLS 1056
P P+P +P G A L EP P L P + P + P+P +
Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK----GPTSTTSDKPAPTT 729
Query: 1057 PIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116
P E T K P P P TS ++S P + P S
Sbjct: 730 PKETAPTTPKEP---APTTPKKPAPTTPETPPPTTS-------EVSTPTTTKEPTTIHKS 779
Query: 1117 GLGEDTAPLDGIDAP----GSQPEPG----QTPGSLASELKGSPVLLDPEELAPVTPMEV 1168
E T L P S EPG +TP + E+ + E TP
Sbjct: 780 P-DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 838
Query: 1169 YPECKQTAGQGSPCEEQEEPRAPVAPTPPT 1198
K T + E+ E + T T
Sbjct: 839 TAAPKMTKETATTTEKTTESKITATTTQVT 868
Score = 92.8 bits (229), Expect = 8e-18
Identities = 135/583 (23%), Positives = 200/583 (34%), Gaps = 72/583 (12%)
Query: 670 PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
P++P P P S + + L+ E + + + + + +E+ +
Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 223
Query: 730 EEPQLCPRSEG-PHLSPRPEEPHLSPR---PEEPHLSPQAEEPHLSPQPEEPCLCAVPEE 785
L P S+ +P+ E P P+EP +P + S P+EP +
Sbjct: 224 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP--TPTTPKEPASTTPKEPTPTTIKSA 281
Query: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS-- 843
P + P P +P T P+EP + E + +P+ P +
Sbjct: 282 PTTPKE-------PAPTTTKSAPTT--------PKEPAPTTTKEPAPTTPKEPAPTTTKE 326
Query: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL-SPLLGEPALSE 902
P P + +P K P P+KP + PAP P P P P +P EPA +
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPTPTTPKEPAPTTKEPAPTT 385
Query: 903 PGEP----PLSPLP----EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL--- 951
P EP P P P E P +P EP+ + P P +P T +AP
Sbjct: 386 PKEPAPTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 444
Query: 952 SPLGELEYPFGAKGDSDPESPLAAPILE---TPISPPPEANCTDPEPVPPMILPPSPGSP 1008
+P P K S + AP P +P A T EP P P+P +
Sbjct: 445 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504
Query: 1009 VGPASPILMEPLPP---QCSPLLQHSLVPQNSPPSQCSPPALPL-SVPSPLSPIGKVVGV 1064
PA EP P + +P L P + P P + P L+P
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564
Query: 1065 SDEAELHEMETEKVSEPECPALEPSATSPL-PSPMGDLSCPAPSPAPALDDFSGLGEDTA 1123
E T K + P P EP+ T+P P+P + P+P + + TA
Sbjct: 565 PTTPEEPAPTTPKAAAPNTPK-EPAPTTPKEPAPT---TPKEPAPTTPKETAPTTPKGTA 620
Query: 1124 PLDGID--------------APGSQPEPGQT---------PGSLASELKGSPVLLDPEEL 1160
P + AP + EP T P A P P+E
Sbjct: 621 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP 680
Query: 1161 APVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSD 1203
AP TP P + +P + + AP PT SD
Sbjct: 681 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 723
Score = 91.3 bits (225), Expect = 2e-17
Identities = 134/572 (23%), Positives = 197/572 (34%), Gaps = 63/572 (11%)
Query: 2108 PQPGALGSPPPAA---APTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDS---PGELFL 2161
P P + S P APT +PTTP + + P P P + P
Sbjct: 273 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 332
Query: 2162 KLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAG 2221
K P P + P AP P EP PT P P+PT P +P + P
Sbjct: 333 KSAPTTPKEPAPTTPKKPAPTTPKEP-----APTTPKEPTPT-TPKEP--APTTKEPAPT 384
Query: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGES 2281
P E T P P P+TP K P+ P+ P K P P +
Sbjct: 385 TPKEPAPTAPKKP--APTTP----KEPAPT-----TPKEPAPTTTKEPSPTTPKEPAPTT 433
Query: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTP-RASQVEP 2340
K+ +E A + + P SP++ K P AP TP + + P
Sbjct: 434 TKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP----APTTPKKPAPTTP 488
Query: 2341 QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP--PPESCCAL 2398
+ P P+EP P P+P T P P TP+ P P +
Sbjct: 489 KEPA-PTTPKEPAPTTTKKPAP------------TTPKEPAPTTPKETAPTTPKKLTPTT 535
Query: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP-PSRP 2457
P + P+ P P +P+ + + +P P P + E P+P TP+ +P+ P P+ P
Sbjct: 536 PEKLAPTTPEKPAPTTPE-ELAPTTPEEPTPTTPEE--PAPTTPKAAAPNTPKEPAPTTP 592
Query: 2458 QSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPN 2517
+ P P K P P P+ A T+ G P L P P
Sbjct: 593 KEPAPTTP--KEPAPTTPK------ETAPTT-PKGTAPTTLKEPAPTTPKKPAPKELAPT 643
Query: 2518 FVRSP-GTGAFVGTPSPMRFTFPQAVGEPS-LKPPVPQPGLPPPHGINSHFGPGPTLGKP 2575
+ P T P+ + T P EP+ P P P P + P PT K
Sbjct: 644 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 703
Query: 2576 QSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQR 2635
+ T P+ + + +T + + + P+ P P + P +
Sbjct: 704 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-- 761
Query: 2636 SGITSPVEKREDPGTGMGSSLATAELPGTQDP 2667
S +++P +E +T EL P
Sbjct: 762 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 793
Score = 63.5 bits (153), Expect = 5e-09
Identities = 91/385 (23%), Positives = 134/385 (34%), Gaps = 57/385 (14%)
Query: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQV 2167
P+ A +P A T +PTTP + + P P P +P E P
Sbjct: 472 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET----APTT 527
Query: 2168 PAQVPSQDPFGLAPAYPLEPRFPTAP----PTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223
P ++ P LAP P +P PT P PT P P+PT P +P A + P A P
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPA-PTTPEELAPTTPEEPTPT-TPEEP----APTTPKAAAP 581
Query: 2224 GEFHTTPPGTPRHQ-PSTPDPFLKPRCPSLDNLAVPESP-GVGGGKASEPLLSPPPFGES 2281
P TP+ P+TP K P+ P +P G EP + P
Sbjct: 582 NTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637
Query: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ 2341
++ +E +++ P +P++ K P AP TP+ +
Sbjct: 638 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP----APTTPKGTAPTTL 693
Query: 2342 SPGLGLRPQEPPPAQAL---------------APSPPSH--PDIFRPGSYTDPYAQPPLT 2384
P++P P + AP+ P P + + T P P T
Sbjct: 694 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 753
Query: 2385 PRPQPPPPESCCALP-----PRSLPSDPFSRVP---ASPQSQSSSQSPLTPRPLSAEAFC 2436
P PPP S + P P ++ P P A P ++ SP P
Sbjct: 754 PE-TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG-------V 805
Query: 2437 PSPVTPRFQSPDPYSRPPSRPQSRD 2461
P+ TP P+ + + RD
Sbjct: 806 PTTKTPAATKPEMTTTAKDKTTERD 830
Score = 53.9 bits (128), Expect = 4e-06
Identities = 94/455 (20%), Positives = 143/455 (31%), Gaps = 52/455 (11%)
Query: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPL-LSPPPFGESRKALEVKKEE 2291
TP+ + +T P L P P+ P K P + P A K
Sbjct: 239 TPKAETTTKGPALTT--PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS- 295
Query: 2292 LGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE 2351
++P P +P++ K P AP T +++ P+ P P++
Sbjct: 296 -APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP----APTTTKSAPTTPKEPA-PTTPKK 349
Query: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPR-PQPPPPESCCALPPRSLPSDPFSR 2410
P P P+P T P P TP+ P P E P P+ P
Sbjct: 350 PAPTTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 397
Query: 2411 VPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP 2470
P +P+ + + +P P P + + PSP TP+ +P P+ + P P
Sbjct: 398 APTTPKEPAPT-TPKEPAPTTTKE--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454
Query: 2471 RPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP-PNFVRSPG------ 2523
P+ P T PA + A +P P + P
Sbjct: 455 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 514
Query: 2524 ------TGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTL-GKPQ 2576
TP + T P+ + + P P P P + P PT +P
Sbjct: 515 PAPTTPKETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEEPA 572
Query: 2577 STNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP----PPAPDGSLPYLSHGA 2632
T A N +P P+ + E +P P P P P G+ P
Sbjct: 573 PTTPKAAAPN-----TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 627
Query: 2633 SQRSGITSPVEKREDPGTGMGSSLATAELPGTQDP 2667
+ + P K P T + T + P P
Sbjct: 628 APTTP-KKPAPKELAPTTTKEPTSTTCDKPAPTTP 661
Score = 49.3 bits (116), Expect = 1e-04
Identities = 83/387 (21%), Positives = 117/387 (30%), Gaps = 50/387 (12%)
Query: 4601 PTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARD 4660
PT P S TK P P+ P P K TP E K A
Sbjct: 453 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 512
Query: 4661 SERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPE---SILGE 4717
E A E PT P +P+ + P + E + E
Sbjct: 513 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEE 570
Query: 4718 EAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFP-DTKPYGALGLEVPGKLPVTTWEK 4776
AP P + +E +P P P + P P T P G P T E
Sbjct: 571 PAPTTPKAAAPNTPKEP---APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 627
Query: 4777 GKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAE 4836
T A K L + K P S P GT P +
Sbjct: 628 AP-------TTPKKPAPKELAPT--------TTKEPTSTTCDKPAPTTPKGTAPTTPKEP 672
Query: 4837 GPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSL-----LKQESPAPEPPTQ 4891
P ++ T P LK+ P +L + + PAP P
Sbjct: 673 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-- 730
Query: 4892 HSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPS--P 4949
++ + P+EP+ P +P P+P +P T P PT P + P
Sbjct: 731 ------------KETAPTTPKEPA-PTTPKKPAPTTPETPP----PTTSEVSTPTTTKEP 773
Query: 4950 LPLASSPESARPKPRARPPEEGEDSRP 4976
+ SP+ + P+ A P + ++ P
Sbjct: 774 TTIHKSPDESTPELSAEPTPKALENSP 800
Score = 47.0 bits (110), Expect = 5e-04
Identities = 82/383 (21%), Positives = 115/383 (30%), Gaps = 35/383 (9%)
Query: 4612 TKNNLSNPPTPPSSLPPTPPPSVQQ--KMVNGVTPSEELGEHPKDAASARDSERALRDTS 4669
T + + PT P PT S K T E PK+ A E A T
Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 333
Query: 4670 EVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGR 4729
+ A PT P E + + P E AP P +
Sbjct: 334 SAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 392
Query: 4730 WEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPG-----KLPVTTWEKGKGSEVSV 4784
++ +P P P TK + P P TT E + S
Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452
Query: 4785 MLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKG 4844
T + + + P P+ PA T PK+ P +K
Sbjct: 453 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKE---PAPTTTKKP 507
Query: 4845 LEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVR 4904
+ P K+ P + + L+ E PAP P
Sbjct: 508 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP--------------E 553
Query: 4905 QLSAPPPEEPSPP----PSPLAPSPASP--PTEPLVELPTEPLAEPPVPSPLPLASSPES 4958
+L+ PEEP+P P+P P A+P P EP P EP P P + E+
Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP--APTTPKEPAPTTPKET 611
Query: 4959 ARPKPRARPPEEGEDSRPPRLKK 4981
A P+ P ++ P KK
Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKK 634
Score = 40.8 bits (94), Expect = 0.038
Identities = 112/590 (18%), Positives = 185/590 (31%), Gaps = 66/590 (11%)
Query: 3999 PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESM 4058
P P KP ++P PT T KE P + T+ P+ A +
Sbjct: 344 PTTPKKPAP--TTPKEPAPT---TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398
Query: 4059 ATEPGEVKPSLSGD-SQLLLVQPQP----QPQPSSLQLQPPLRLPGQQQQQVSLLHTAGG 4113
T P E P+ + + +P P +P P++ + P T
Sbjct: 399 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT---------------TTKE 443
Query: 4114 GSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPP 4173
+ S ++ P +P+ + +P T P P P T P+ P
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP----TTPKEP 499
Query: 4174 KPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQ 4233
P + P PT + A L+P ++ A +L
Sbjct: 500 APTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEELAP 557
Query: 4234 SQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP--PRLPA 4291
+ TP E T+P P P P T P + P+ P P+ A
Sbjct: 558 TTPEEPTPTTPEEPAPTTPK----AAAPNTPKEPAPTT-PKEPAPTTPKEPAPTTPKETA 612
Query: 4292 PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTL 4351
P T P P P++P++P P +L +++ PT P TPK PT
Sbjct: 613 PTTPKGTAPT---TLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 668
Query: 4352 EPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAET-QKPEQSSLVPGHLDQVNGQVVPEA 4410
P +P + A T KG P + T +KP L P +
Sbjct: 669 PKEPAPTTP--KEPAPTT-PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725
Query: 4411 SQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAK 4470
+ + K+ P + K+ A P P T++ + E
Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE------------- 772
Query: 4471 NVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPK-----RV 4525
+ + + E++ K K G P+ K AA + +T K R
Sbjct: 773 --PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 830
Query: 4526 QKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSL 4575
+ + ++ K+ KE + ++ + + T T F +
Sbjct: 831 LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 880
Score = 40.8 bits (94), Expect = 0.038
Identities = 84/369 (22%), Positives = 108/369 (29%), Gaps = 49/369 (13%)
Query: 4620 PTPPSSLPPTP--PPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLL 4677
PT S P TP P K TP E PK A E A E
Sbjct: 446 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 505
Query: 4678 AALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRAL 4737
PT P E+ + P + P ++PE + AP P + +E L
Sbjct: 506 KPAPTTPKEPAPTTPKETAPTT--PKKLTP-TTPEKL----APTTPEKPAPTTPEE---L 555
Query: 4738 SPVIPLIPRASIPVFP-DTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNL 4796
+P P P + P P T P A P T E + T A
Sbjct: 556 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 615
Query: 4797 NGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDW 4856
L P + P+ PA P + +K T P
Sbjct: 616 PKGTAPTT--LKEPAPTT-----PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 668
Query: 4857 LKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSP 4916
K+ P + PAP P + T L P P P
Sbjct: 669 PKEPAPTTP----------------KEPAPTTPKGTAPT---------TLKEPAPTTPKK 703
Query: 4917 P-PSPLAPSPASPPTEPLVE--LPTEPLAEPPVPSPLPLASSPESARP-KPRARPPEEGE 4972
P P LAP+ PT + PT P P P ++P+ P P PP E
Sbjct: 704 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 763
Query: 4973 DSRPPRLKK 4981
S P K+
Sbjct: 764 VSTPTTTKE 772
Score = 38.1 bits (87), Expect = 0.24
Identities = 34/123 (27%), Positives = 44/123 (35%), Gaps = 13/123 (10%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP--PRLPAPPGALS 4297
TP P T P P P P T P + P+ P P+ P P +
Sbjct: 315 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPTP----T 369
Query: 4298 TGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR 4357
T P P P++P+EP + P PT + P P TPK PT P
Sbjct: 370 TPKEPAPTTKEPAPTTPKEPAPTA----PKKPAPTTPKEPA--PTTPKEPAPTTTKEPSP 423
Query: 4358 VSP 4360
+P
Sbjct: 424 TTP 426
Score = 35.8 bits (81), Expect = 1.2
Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 3/108 (2%)
Query: 4877 SLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP-PEEPSPPPSPLAP-SPASP-PTEPL 4933
+L + P P P + + T SAP P+EP+P + AP +P P PT
Sbjct: 250 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 309
Query: 4934 VELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKK 4981
PT P P + P ++ +SA P+ P + P K+
Sbjct: 310 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357
Score = 34.7 bits (78), Expect = 2.7
Identities = 36/126 (28%), Positives = 44/126 (34%), Gaps = 8/126 (6%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPP--RLPAPPGALS 4297
TP T P + P P P T + P+ P + PAP
Sbjct: 261 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT--TKSAPTTPKEPAPTTTKEPAPTTPKE 318
Query: 4298 TGPVLGPVH-PTPPPSSPQEPKRPSQLPSPSSQLPTEAQLP-PTHPGTPKPQGPTLEPPP 4355
P PT S+P PK P+ +P PT + P PT P P P P EP P
Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPTPTTPK-EPAP 376
Query: 4356 GRVSPA 4361
PA
Sbjct: 377 TTKEPA 382
Score = 33.9 bits (76), Expect = 4.6
Identities = 44/198 (22%), Positives = 68/198 (34%), Gaps = 11/198 (5%)
Query: 4165 QNNTGPQP-PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQ 4223
+N T +P PKP V ++G GL T ++ +P++ P +
Sbjct: 112 KNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSL 171
Query: 4224 ALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRP 4283
+ S V + + T T+ Q + + +T +++ A
Sbjct: 172 PPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTS--AKETQSIEKTSAKDLA 229
Query: 4284 QGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT 4343
L P T GP TP +P PK P+ +P PT + PT P
Sbjct: 230 PTSKVLAKPTPKAET-TTKGPALTTPKEPTPTTPKEPAS-TTPKEPTPTTIKSAPTTPKE 287
Query: 4344 PKP----QGPTL--EPPP 4355
P P PT EP P
Sbjct: 288 PAPTTTKSAPTTPKEPAP 305
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 146 bits (369), Expect = 5e-34
Identities = 153/622 (24%), Positives = 244/622 (39%), Gaps = 77/622 (12%)
Query: 362 AEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGK 421
AE T + +P EP T EP S PKEP P ++ P
Sbjct: 294 AETTTKGPALTTPKEPTPTTPKEP----------------ASTTPKEPTPTTIKSAPTTP 337
Query: 422 AGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTS---PPPEASRLSPPPEELPASP 478
AP + P +E + P E +PT+ P P ++ +P + PA
Sbjct: 338 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 397
Query: 479 LPEALHLSRPLEESPLSP--PPEESPLSPPP---ESSPFSPLEESPLSPPEESPPSPALE 533
P+ + P E +P +P P +P P P E +P +P E +P +P + +P +P
Sbjct: 398 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 457
Query: 534 TPLSP-PPEASPLSPPFEESPLSPPP---EELPTS---PPPEASRLSPPPEESPMSPPPE 586
P +P P + P +P P P + PT+ P P ++ +P + P SP
Sbjct: 458 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTT 516
Query: 587 ESPMSPPPEASRLFPPFEESPLSP--PPEESPLSPPPEASRLSPP--PEDSPMSPPPEES 642
+ P P+ P + +P +P P +P P P ++ P P++ + P E +
Sbjct: 517 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576
Query: 643 PMSP----PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP------PPEASRLSPP 692
P +P P +L+P PEE + P E +PT+P P+A+ + P
Sbjct: 577 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 636
Query: 693 PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL 752
E +PT+P PA P++ + P E +P P P + P +P L
Sbjct: 637 KEPAPTTP---KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL-KEPAPTTPKKPAPKEL 692
Query: 753 SPRPEEPHLSPQAEEP-HLSPQ------PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805
+P + S ++P +P+ P+EP E +P+ P +P
Sbjct: 693 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP---- 748
Query: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
+P T + P P+E L+P + S S++P P+E+ +P K P P+
Sbjct: 749 -APTTPK---KPAPKE--LAPTTTKGPTSTTSDKPA-PTTPKET--APTTPKEPAPTTPK 799
Query: 866 KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSL 925
KP + P P + P + + P S P E P P+ L SP EP
Sbjct: 800 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPK-EPG- 856
Query: 926 SPQLMPPDPLPPPLSPIITAAA 947
+P P P +T A
Sbjct: 857 ----VPTTKTPAATKPEMTTTA 874
Score = 144 bits (363), Expect = 2e-33
Identities = 146/593 (24%), Positives = 226/593 (38%), Gaps = 67/593 (11%)
Query: 416 AKPLGKAGVQLE-PQLEAPLNEEMPLLP--PPEESPLSPPPEE------SPTSPPPEASR 466
AKP KA + P L P E P P P +P P P +P P P ++
Sbjct: 288 AKPTPKAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 346
Query: 467 LSPPPEELPASPLPEALHLSRPLEESPLS---PPPEESPLSP--PPESSPFSPLEESPLS 521
+P + PA + + P E +P + P P + +P P E +P +P + +P +
Sbjct: 347 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 406
Query: 522 PPEESPPSPALETPLSPPPEASPLSPPFEESPLSP----PPEELPTSPPPEASRLSPPPE 577
P E +P +P TP +P A P +P P P + PT+P A P
Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466
Query: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP--PPEASRLSP----PPE 631
+ P +P P P ++ P + P + +P +P P + P P E
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526
Query: 632 DSPMSP--PPEESPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPEESPTSP----P 683
+P +P P +P P P + P P ++ P P+E + P E +PT+P P
Sbjct: 527 PAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 585
Query: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP------LPEEPQLCPR 737
+L+P + P PE+ A PE+ + P E +P P P+EP P
Sbjct: 586 TTPEKLAPTTPEKPAPTTPEEL-APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP--APT 642
Query: 738 SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797
+ P+EP + E +P+ P +P P++P +P+ P
Sbjct: 643 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP----TTPKKP--APKELAPTT 696
Query: 798 SPQPEELHL---SPQTEEPHLSPVPEEPCLSPQPEESHLSP--------QSEEPCLSPRP 846
+ +P +P T + P+EP + E + +P + P +P
Sbjct: 697 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 756
Query: 847 EESHLSPELEKPPLSPRPEKP----PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902
L+P K P S +KP P+E E P P P+ +P P SE
Sbjct: 757 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE 815
Query: 903 PGEPPLSPLPEELPLSP-SGEPSLSPQLMPPDPLPPPLSP-IITAAAPPALSP 953
P + P + SP P LS + P P P + T P A P
Sbjct: 816 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 868
Score = 133 bits (334), Expect = 6e-30
Identities = 157/658 (23%), Positives = 247/658 (37%), Gaps = 124/658 (18%)
Query: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG-KAGVQLEPQLE 431
+P EP T EP T PKEP P E P K P+
Sbjct: 406 TPKEPAPTTPKEP----------------TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 449
Query: 432 APLNEEMPLLPPPEESPLSPPPEESPTSPP---PEASRLSPPPEELPASPLPEALHLSRP 488
AP + P P+E + E SPT+P P ++ +P + PA P + P
Sbjct: 450 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTP 508
Query: 489 LEESPLSPP------PEESPLSPPPESSPFSPLEESPLSPPEESPPS---PALETPLSPP 539
E SP + P+E + P + +P +P E +P +P E +P + PA TP P
Sbjct: 509 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 568
Query: 540 PEASPLSPPFEESPLSPP-PEEL-PTSP----PPEASRLSPPPEESPMSPPPEESPMSPP 593
P + P L+P PE+L PT+P P L+P E P PEE P
Sbjct: 569 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE-PAPTT 627
Query: 594 PEASRLFPPFEESPLSP-------PPEESPLSPPPEA---------SRLSPPPEDSPMSP 637
P+A+ P E +P +P P E +P +P A + L P +P P
Sbjct: 628 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 687
Query: 638 PPEE---SPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPEESPTSPPPEA-SRLSP 691
P+E + P + P P + + P P+E + P E +PT+P A + L
Sbjct: 688 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 747
Query: 692 PPEDSPTSPPPE---------------DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736
P +P P P+ D PA P+++ + P E +P P P P
Sbjct: 748 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT-P 806
Query: 737 RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL----SPQA 792
+ P S P + P H SP P LS +P L P+EP + +P A
Sbjct: 807 ETPPPTTS-EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 865
Query: 793 EGPHLSPQPEE------LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE------- 839
P ++ ++ L +P+T E + + ES ++ + +
Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 925
Query: 840 ------------PCLSPR----------------PEESHLSPE--LEKPPLSPRPEKPPE 869
L+P+ PEE+ + +P+P+KP +
Sbjct: 926 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 985
Query: 870 EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927
P + + ++ P +P +P + + P P S + E + L + P+ +P
Sbjct: 986 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAM-LQTTTRPNQTP 1042
Score = 130 bits (327), Expect = 4e-29
Identities = 169/750 (22%), Positives = 249/750 (33%), Gaps = 89/750 (11%)
Query: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPE------------ESPPSPALETPLSPPP 540
P++P P P S + + + +E+ + E + + A ET
Sbjct: 216 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 275
Query: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP--PPEESPMSPPPEASR 598
A L+P + P E T P L+ P E +P +P P +P P P +
Sbjct: 276 SAKDLAPTSKVLAKPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTPTTIK 331
Query: 599 LFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV 658
P + P + +P +P A + P + P + P P ++ +P
Sbjct: 332 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 391
Query: 659 VSRLSPPPEESPLSPPPEESPTSP--PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM 716
P++ + P E +PT+P P + P P +P PA P+
Sbjct: 392 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Query: 717 SLPLEESPLLP--------------LPEEPQLCPRSEGPHLS--PRPEEPHLSP-RPEEP 759
+ P E +P P P+EP P + P P +P P+EP
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511
Query: 760 HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819
SP + P+EP + +P+ P +P +P T + P
Sbjct: 512 --SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP-----APTTTKKPAPTTP 564
Query: 820 EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP-PLSPRPEKP--PEEPGQCPA 876
+EP + E + +P+ L+P E EKP P +P P PEEP
Sbjct: 565 KEPAPTTPKETAPTTPKK----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 620
Query: 877 PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
E P P P+ EPA + P EP + E P +P +P+ P L
Sbjct: 621 EEPAPTTPKAAAPNTPK---EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 677
Query: 937 PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV 996
P AP L+P E P D P +P A T EP
Sbjct: 678 EPAPTTPKKPAPKELAPTTTKE-PTSTTCDK-----------PAPTTPKGTAPTTPKEPA 725
Query: 997 PPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLS 1056
P P+P +P G A L EP P L P + P + P+P +
Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK----GPTSTTSDKPAPTT 781
Query: 1057 PIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116
P E T K P P P TS ++S P + P S
Sbjct: 782 PKETAPTTPKEP---APTTPKKPAPTTPETPPPTTS-------EVSTPTTTKEPTTIHKS 831
Query: 1117 GLGEDTAPLDGIDAP----GSQPEPG----QTPGSLASELKGSPVLLDPEELAPVTPMEV 1168
E T L P S EPG +TP + E+ + E TP
Sbjct: 832 P-DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 890
Query: 1169 YPECKQTAGQGSPCEEQEEPRAPVAPTPPT 1198
K T + E+ E + T T
Sbjct: 891 TAAPKMTKETATTTEKTTESKITATTTQVT 920
Score = 97.1 bits (240), Expect = 4e-19
Identities = 165/754 (21%), Positives = 251/754 (33%), Gaps = 92/754 (12%)
Query: 507 PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP 566
P+ F +P SPP +PPP + + PP + T
Sbjct: 57 PDYESFCAEVHNPTSPPSSKK---------APPPSGASQTIKSTTKRSPKPPNKKKTKKV 107
Query: 567 PEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626
E+ ++ EE +S E S S +S + S S E + ++
Sbjct: 108 IESEEIT---EEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKK 164
Query: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS-----RLSPPPE---ESPLSPPPEES 678
+ + PP + S P S ++S P+ P++P P
Sbjct: 165 NRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP 224
Query: 679 PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
P S + + L+ E + + + + + +E+ + L P S
Sbjct: 225 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 284
Query: 739 EG-PHLSPRPEEPHLSPR---PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794
+ +P+ E P P+EP +P + S P+EP + P +
Sbjct: 285 KVLAKPTPKAETTTKGPALTTPKEP--TPTTPKEPASTTPKEPTPTTIKSAPTTPKE--- 339
Query: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS--PRPEESHLS 852
P P +P T P+EP + E + +P+ P + P P + +
Sbjct: 340 ----PAPTTTKSAPTT--------PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 387
Query: 853 PELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL-SPLLGEPALSEPGEP----P 907
P K P P+KP + PAP P P P P +P EPA + P EP P
Sbjct: 388 PTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 446
Query: 908 LSPLP----EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL---SPLGELEYP 960
P P E P +P EP+ + P P +P T +AP +P P
Sbjct: 447 KKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 505
Query: 961 FGAKGDSDPESPLAAPILE---TPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILM 1017
K S + AP P +P A T EP P P+P + PA
Sbjct: 506 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 565
Query: 1018 EPLPP---QCSPLLQHSLVPQNSPPSQCSPPALPL-SVPSPLSPIGKVVGVSDEAELHEM 1073
EP P + +P L P + P P + P L+P E
Sbjct: 566 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 625
Query: 1074 ETEKVSEPECPALEPSATSPL-PSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGID--- 1129
T K + P P EP+ T+P P+P + P+P + + TAP +
Sbjct: 626 TTPKAAAPNTPK-EPAPTTPKEPAPT---TPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 681
Query: 1130 -----------APGSQPEPGQT---------PGSLASELKGSPVLLDPEELAPVTPMEVY 1169
AP + EP T P A P P+E AP TP
Sbjct: 682 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 741
Query: 1170 PECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSD 1203
P + +P + + AP PT SD
Sbjct: 742 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 775
Score = 91.3 bits (225), Expect = 2e-17
Identities = 134/572 (23%), Positives = 197/572 (34%), Gaps = 63/572 (11%)
Query: 2108 PQPGALGSPPPAA---APTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDS---PGELFL 2161
P P + S P APT +PTTP + + P P P + P
Sbjct: 325 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 384
Query: 2162 KLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAG 2221
K P P + P AP P EP PT P P+PT P +P + P
Sbjct: 385 KSAPTTPKEPAPTTPKKPAPTTPKEP-----APTTPKEPTPT-TPKEP--APTTKEPAPT 436
Query: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGES 2281
P E T P P P+TP K P+ P+ P K P P +
Sbjct: 437 TPKEPAPTAPKKP--APTTP----KEPAPT-----TPKEPAPTTTKEPSPTTPKEPAPTT 485
Query: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTP-RASQVEP 2340
K+ +E A + + P SP++ K P AP TP + + P
Sbjct: 486 TKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP----APTTPKKPAPTTP 540
Query: 2341 QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP--PPESCCAL 2398
+ P P+EP P P+P T P P TP+ P P +
Sbjct: 541 KEPA-PTTPKEPAPTTTKKPAP------------TTPKEPAPTTPKETAPTTPKKLTPTT 587
Query: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP-PSRP 2457
P + P+ P P +P+ + + +P P P + E P+P TP+ +P+ P P+ P
Sbjct: 588 PEKLAPTTPEKPAPTTPE-ELAPTTPEEPTPTTPEE--PAPTTPKAAAPNTPKEPAPTTP 644
Query: 2458 QSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPN 2517
+ P P K P P P+ A T+ G P L P P
Sbjct: 645 KEPAPTTP--KEPAPTTPK------ETAPTT-PKGTAPTTLKEPAPTTPKKPAPKELAPT 695
Query: 2518 FVRSP-GTGAFVGTPSPMRFTFPQAVGEPS-LKPPVPQPGLPPPHGINSHFGPGPTLGKP 2575
+ P T P+ + T P EP+ P P P P + P PT K
Sbjct: 696 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 755
Query: 2576 QSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQR 2635
+ T P+ + + +T + + + P+ P P + P +
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-- 813
Query: 2636 SGITSPVEKREDPGTGMGSSLATAELPGTQDP 2667
S +++P +E +T EL P
Sbjct: 814 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 845
Score = 63.5 bits (153), Expect = 5e-09
Identities = 91/385 (23%), Positives = 134/385 (34%), Gaps = 57/385 (14%)
Query: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQV 2167
P+ A +P A T +PTTP + + P P P +P E P
Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET----APTT 579
Query: 2168 PAQVPSQDPFGLAPAYPLEPRFPTAP----PTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223
P ++ P LAP P +P PT P PT P P+PT P +P A + P A P
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPA-PTTPEELAPTTPEEPTPT-TPEEP----APTTPKAAAP 633
Query: 2224 GEFHTTPPGTPRHQ-PSTPDPFLKPRCPSLDNLAVPESP-GVGGGKASEPLLSPPPFGES 2281
P TP+ P+TP K P+ P +P G EP + P
Sbjct: 634 NTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689
Query: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ 2341
++ +E +++ P +P++ K P AP TP+ +
Sbjct: 690 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP----APTTPKGTAPTTL 745
Query: 2342 SPGLGLRPQEPPPAQAL---------------APSPPSH--PDIFRPGSYTDPYAQPPLT 2384
P++P P + AP+ P P + + T P P T
Sbjct: 746 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 805
Query: 2385 PRPQPPPPESCCALP-----PRSLPSDPFSRVP---ASPQSQSSSQSPLTPRPLSAEAFC 2436
P PPP S + P P ++ P P A P ++ SP P
Sbjct: 806 PE-TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG-------V 857
Query: 2437 PSPVTPRFQSPDPYSRPPSRPQSRD 2461
P+ TP P+ + + RD
Sbjct: 858 PTTKTPAATKPEMTTTAKDKTTERD 882
Score = 53.9 bits (128), Expect = 4e-06
Identities = 94/455 (20%), Positives = 143/455 (31%), Gaps = 52/455 (11%)
Query: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPL-LSPPPFGESRKALEVKKEE 2291
TP+ + +T P L P P+ P K P + P A K
Sbjct: 291 TPKAETTTKGPALTT--PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS- 347
Query: 2292 LGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE 2351
++P P +P++ K P AP T +++ P+ P P++
Sbjct: 348 -APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP----APTTTKSAPTTPKEPA-PTTPKK 401
Query: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPR-PQPPPPESCCALPPRSLPSDPFSR 2410
P P P+P T P P TP+ P P E P P+ P
Sbjct: 402 PAPTTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 449
Query: 2411 VPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP 2470
P +P+ + + +P P P + + PSP TP+ +P P+ + P P
Sbjct: 450 APTTPKEPAPT-TPKEPAPTTTKE--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506
Query: 2471 RPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP-PNFVRSPG------ 2523
P+ P T PA + A +P P + P
Sbjct: 507 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 566
Query: 2524 ------TGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTL-GKPQ 2576
TP + T P+ + + P P P P + P PT +P
Sbjct: 567 PAPTTPKETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEEPA 624
Query: 2577 STNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP----PPAPDGSLPYLSHGA 2632
T A N +P P+ + E +P P P P P G+ P
Sbjct: 625 PTTPKAAAPN-----TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 679
Query: 2633 SQRSGITSPVEKREDPGTGMGSSLATAELPGTQDP 2667
+ + P K P T + T + P P
Sbjct: 680 APTTP-KKPAPKELAPTTTKEPTSTTCDKPAPTTP 713
Score = 49.3 bits (116), Expect = 1e-04
Identities = 83/387 (21%), Positives = 117/387 (30%), Gaps = 50/387 (12%)
Query: 4601 PTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARD 4660
PT P S TK P P+ P P K TP E K A
Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 564
Query: 4661 SERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPE---SILGE 4717
E A E PT P +P+ + P + E + E
Sbjct: 565 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEE 622
Query: 4718 EAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFP-DTKPYGALGLEVPGKLPVTTWEK 4776
AP P + +E +P P P + P P T P G P T E
Sbjct: 623 PAPTTPKAAAPNTPKEP---APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 679
Query: 4777 GKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAE 4836
T A K L + K P S P GT P +
Sbjct: 680 AP-------TTPKKPAPKELAPT--------TTKEPTSTTCDKPAPTTPKGTAPTTPKEP 724
Query: 4837 GPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSL-----LKQESPAPEPPTQ 4891
P ++ T P LK+ P +L + + PAP P
Sbjct: 725 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-- 782
Query: 4892 HSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPS--P 4949
++ + P+EP+ P +P P+P +P T P PT P + P
Sbjct: 783 ------------KETAPTTPKEPA-PTTPKKPAPTTPETPP----PTTSEVSTPTTTKEP 825
Query: 4950 LPLASSPESARPKPRARPPEEGEDSRP 4976
+ SP+ + P+ A P + ++ P
Sbjct: 826 TTIHKSPDESTPELSAEPTPKALENSP 852
Score = 47.0 bits (110), Expect = 5e-04
Identities = 82/383 (21%), Positives = 115/383 (30%), Gaps = 35/383 (9%)
Query: 4612 TKNNLSNPPTPPSSLPPTPPPSVQQ--KMVNGVTPSEELGEHPKDAASARDSERALRDTS 4669
T + + PT P PT S K T E PK+ A E A T
Sbjct: 326 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385
Query: 4670 EVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGR 4729
+ A PT P E + + P E AP P +
Sbjct: 386 SAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 444
Query: 4730 WEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPG-----KLPVTTWEKGKGSEVSV 4784
++ +P P P TK + P P TT E + S
Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504
Query: 4785 MLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKG 4844
T + + + P P+ PA T PK+ P +K
Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKE---PAPTTTKKP 559
Query: 4845 LEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVR 4904
+ P K+ P + + L+ E PAP P
Sbjct: 560 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP--------------E 605
Query: 4905 QLSAPPPEEPSPP----PSPLAPSPASP--PTEPLVELPTEPLAEPPVPSPLPLASSPES 4958
+L+ PEEP+P P+P P A+P P EP P EP P P + E+
Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP--APTTPKEPAPTTPKET 663
Query: 4959 ARPKPRARPPEEGEDSRPPRLKK 4981
A P+ P ++ P KK
Sbjct: 664 APTTPKGTAPTTLKEPAPTTPKK 686
Score = 42.7 bits (99), Expect = 0.010
Identities = 84/389 (21%), Positives = 128/389 (32%), Gaps = 47/389 (12%)
Query: 4604 PDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSER 4663
PDY S + NP +PPSS PPPS + + T + K +SE
Sbjct: 57 PDYESFCA---EVHNPTSPPSS-KKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEE 112
Query: 4664 ALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPA--SSPESILGEEAPR 4721
T H+ +E+ S S S S + SS S E +
Sbjct: 113 I-----------------TEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQK 155
Query: 4722 FPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSE 4781
+ + + + +P P++ A GL+ G VTT +
Sbjct: 156 KLKVKDNKKNRTKKKPTPKPPVVDEAGS------------GLD-NGDFKVTTPDTSTTQH 202
Query: 4782 VSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGK 4841
V + AK +N + K + + E+ + GK
Sbjct: 203 NKVSTSPKITTAKPINPRPSLPPNSDTSK--ETSLTVNKETTVETKETTTTNKQTSTDGK 260
Query: 4842 EKGLEGKSPD----TGPDWLKQFDAVLPGYTLKSQLDIL--SLLKQESPAPEPPTQHSYT 4895
EK K T L VL T K++ +L + P P P + + T
Sbjct: 261 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST 320
Query: 4896 YNVSNLDVRQLSAPP-PEEPSPPPSPLAP-SPASP-PTEPLVELPTEPLAEPPVPSPLPL 4952
SAP P+EP+P + AP +P P PT PT P P + P
Sbjct: 321 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 380
Query: 4953 ASSPESARPKPRARPPEEGEDSRPPRLKK 4981
++ +SA P+ P + P K+
Sbjct: 381 PTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409
Score = 40.8 bits (94), Expect = 0.038
Identities = 112/590 (18%), Positives = 185/590 (31%), Gaps = 66/590 (11%)
Query: 3999 PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESM 4058
P P KP ++P PT T KE P + T+ P+ A +
Sbjct: 396 PTTPKKPAP--TTPKEPAPT---TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450
Query: 4059 ATEPGEVKPSLSGD-SQLLLVQPQP----QPQPSSLQLQPPLRLPGQQQQQVSLLHTAGG 4113
T P E P+ + + +P P +P P++ + P T
Sbjct: 451 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT---------------TTKE 495
Query: 4114 GSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPP 4173
+ S ++ P +P+ + +P T P P P T P+ P
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP----TTPKEP 551
Query: 4174 KPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQ 4233
P + P PT + A L+P ++ A +L
Sbjct: 552 APTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEELAP 609
Query: 4234 SQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP--PRLPA 4291
+ TP E T+P P P P T P + P+ P P+ A
Sbjct: 610 TTPEEPTPTTPEEPAPTTPK----AAAPNTPKEPAPTT-PKEPAPTTPKEPAPTTPKETA 664
Query: 4292 PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTL 4351
P T P P P++P++P P +L +++ PT P TPK PT
Sbjct: 665 PTTPKGTAPT---TLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 720
Query: 4352 EPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAET-QKPEQSSLVPGHLDQVNGQVVPEA 4410
P +P + A T KG P + T +KP L P +
Sbjct: 721 PKEPAPTTP--KEPAPTT-PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777
Query: 4411 SQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAK 4470
+ + K+ P + K+ A P P T++ + E
Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE------------- 824
Query: 4471 NVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPK-----RV 4525
+ + + E++ K K G P+ K AA + +T K R
Sbjct: 825 --PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 882
Query: 4526 QKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSL 4575
+ + ++ K+ KE + ++ + + T T F +
Sbjct: 883 LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 932
Score = 40.8 bits (94), Expect = 0.038
Identities = 84/369 (22%), Positives = 108/369 (29%), Gaps = 49/369 (13%)
Query: 4620 PTPPSSLPPTP--PPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLL 4677
PT S P TP P K TP E PK A E A E
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 557
Query: 4678 AALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRAL 4737
PT P E+ + P + P ++PE + AP P + +E L
Sbjct: 558 KPAPTTPKEPAPTTPKETAPTT--PKKLTP-TTPEKL----APTTPEKPAPTTPEE---L 607
Query: 4738 SPVIPLIPRASIPVFP-DTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNL 4796
+P P P + P P T P A P T E + T A
Sbjct: 608 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 667
Query: 4797 NGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDW 4856
L P + P+ PA P + +K T P
Sbjct: 668 PKGTAPTT--LKEPAPTT-----PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 720
Query: 4857 LKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSP 4916
K+ P + PAP P + T L P P P
Sbjct: 721 PKEPAPTTP----------------KEPAPTTPKGTAPT---------TLKEPAPTTPKK 755
Query: 4917 P-PSPLAPSPASPPTEPLVE--LPTEPLAEPPVPSPLPLASSPESARP-KPRARPPEEGE 4972
P P LAP+ PT + PT P P P ++P+ P P PP E
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 815
Query: 4973 DSRPPRLKK 4981
S P K+
Sbjct: 816 VSTPTTTKE 824
Score = 38.1 bits (87), Expect = 0.24
Identities = 34/123 (27%), Positives = 44/123 (35%), Gaps = 13/123 (10%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP--PRLPAPPGALS 4297
TP P T P P P P T P + P+ P P+ P P +
Sbjct: 367 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPTP----T 421
Query: 4298 TGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR 4357
T P P P++P+EP + P PT + P P TPK PT P
Sbjct: 422 TPKEPAPTTKEPAPTTPKEPAPTA----PKKPAPTTPKEPA--PTTPKEPAPTTTKEPSP 475
Query: 4358 VSP 4360
+P
Sbjct: 476 TTP 478
Score = 36.6 bits (83), Expect = 0.71
Identities = 57/296 (19%), Positives = 104/296 (35%), Gaps = 24/296 (8%)
Query: 4067 PSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSE 4126
P SG SQ + + P+P + + + + ++++ H+ S SSS
Sbjct: 79 PPPSGASQTIKSTTKRSPKPPNKKKTKKVI----ESEEITEEHSVSENQESSSSSSSSSS 134
Query: 4127 ASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQP-PKPGPVLQSGQGL 4185
+S++ + + + + + + ++ +N T +P PKP V ++G GL
Sbjct: 135 SSTIRKIKSSKNSAANRELQKKLK---------VKDNKKNRTKKKPTPKPPVVDEAGSGL 185
Query: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245
T ++ +P++ P + + S V + +
Sbjct: 186 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 245
Query: 4246 PGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPV 4305
T T+ Q + + +T +++ A L P T GP
Sbjct: 246 KETTTTNKQTSTDGKEKTTS--AKETQSIEKTSAKDLAPTSKVLAKPTPKAET-TTKGPA 302
Query: 4306 HPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP----QGPTL--EPPP 4355
TP +P PK P+ +P PT + PT P P P PT EP P
Sbjct: 303 LTTPKEPTPTTPKEPAS-TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP 357
Score = 34.7 bits (78), Expect = 2.7
Identities = 36/126 (28%), Positives = 44/126 (34%), Gaps = 8/126 (6%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPP--RLPAPPGALS 4297
TP T P + P P P T + P+ P + PAP
Sbjct: 313 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT--TKSAPTTPKEPAPTTTKEPAPTTPKE 370
Query: 4298 TGPVLGPVH-PTPPPSSPQEPKRPSQLPSPSSQLPTEAQLP-PTHPGTPKPQGPTLEPPP 4355
P PT S+P PK P+ +P PT + P PT P P P P EP P
Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPTPTTPK-EPAP 428
Query: 4356 GRVSPA 4361
PA
Sbjct: 429 TTKEPA 434
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 146 bits (369), Expect = 5e-34
Identities = 153/622 (24%), Positives = 244/622 (39%), Gaps = 77/622 (12%)
Query: 362 AEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGK 421
AE T + +P EP T EP S PKEP P ++ P
Sbjct: 335 AETTTKGPALTTPKEPTPTTPKEP----------------ASTTPKEPTPTTIKSAPTTP 378
Query: 422 AGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTS---PPPEASRLSPPPEELPASP 478
AP + P +E + P E +PT+ P P ++ +P + PA
Sbjct: 379 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 438
Query: 479 LPEALHLSRPLEESPLSP--PPEESPLSPPP---ESSPFSPLEESPLSPPEESPPSPALE 533
P+ + P E +P +P P +P P P E +P +P E +P +P + +P +P
Sbjct: 439 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 498
Query: 534 TPLSP-PPEASPLSPPFEESPLSPPP---EELPTS---PPPEASRLSPPPEESPMSPPPE 586
P +P P + P +P P P + PT+ P P ++ +P + P SP
Sbjct: 499 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTT 557
Query: 587 ESPMSPPPEASRLFPPFEESPLSP--PPEESPLSPPPEASRLSPP--PEDSPMSPPPEES 642
+ P P+ P + +P +P P +P P P ++ P P++ + P E +
Sbjct: 558 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617
Query: 643 PMSP----PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP------PPEASRLSPP 692
P +P P +L+P PEE + P E +PT+P P+A+ + P
Sbjct: 618 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 677
Query: 693 PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL 752
E +PT+P PA P++ + P E +P P P + P +P L
Sbjct: 678 KEPAPTTP---KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL-KEPAPTTPKKPAPKEL 733
Query: 753 SPRPEEPHLSPQAEEP-HLSPQ------PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805
+P + S ++P +P+ P+EP E +P+ P +P
Sbjct: 734 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP---- 789
Query: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
+P T + P P+E L+P + S S++P P+E+ +P K P P+
Sbjct: 790 -APTTPK---KPAPKE--LAPTTTKGPTSTTSDKPA-PTTPKET--APTTPKEPAPTTPK 840
Query: 866 KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSL 925
KP + P P + P + + P S P E P P+ L SP EP
Sbjct: 841 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP-ELSAEPTPKALENSPK-EPG- 897
Query: 926 SPQLMPPDPLPPPLSPIITAAA 947
+P P P +T A
Sbjct: 898 ----VPTTKTPAATKPEMTTTA 915
Score = 144 bits (363), Expect = 2e-33
Identities = 146/593 (24%), Positives = 226/593 (38%), Gaps = 67/593 (11%)
Query: 416 AKPLGKAGVQLE-PQLEAPLNEEMPLLP--PPEESPLSPPPEE------SPTSPPPEASR 466
AKP KA + P L P E P P P +P P P +P P P ++
Sbjct: 329 AKPTPKAETTTKGPALTTP-KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 387
Query: 467 LSPPPEELPASPLPEALHLSRPLEESPLS---PPPEESPLSP--PPESSPFSPLEESPLS 521
+P + PA + + P E +P + P P + +P P E +P +P + +P +
Sbjct: 388 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 447
Query: 522 PPEESPPSPALETPLSPPPEASPLSPPFEESPLSP----PPEELPTSPPPEASRLSPPPE 577
P E +P +P TP +P A P +P P P + PT+P A P
Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507
Query: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP--PPEASRLSP----PPE 631
+ P +P P P ++ P + P + +P +P P + P P E
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567
Query: 632 DSPMSP--PPEESPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPEESPTSP----P 683
+P +P P +P P P + P P ++ P P+E + P E +PT+P P
Sbjct: 568 PAPTTPKKPAPTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 626
Query: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP------LPEEPQLCPR 737
+L+P + P PE+ A PE+ + P E +P P P+EP P
Sbjct: 627 TTPEKLAPTTPEKPAPTTPEEL-APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP--APT 683
Query: 738 SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797
+ P+EP + E +P+ P +P P++P +P+ P
Sbjct: 684 TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP----TTPKKP--APKELAPTT 737
Query: 798 SPQPEELHL---SPQTEEPHLSPVPEEPCLSPQPEESHLSP--------QSEEPCLSPRP 846
+ +P +P T + P+EP + E + +P + P +P
Sbjct: 738 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 797
Query: 847 EESHLSPELEKPPLSPRPEKP----PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902
L+P K P S +KP P+E E P P P+ +P P SE
Sbjct: 798 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE 856
Query: 903 PGEPPLSPLPEELPLSP-SGEPSLSPQLMPPDPLPPPLSP-IITAAAPPALSP 953
P + P + SP P LS + P P P + T P A P
Sbjct: 857 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 909
Score = 133 bits (334), Expect = 6e-30
Identities = 157/658 (23%), Positives = 247/658 (37%), Gaps = 124/658 (18%)
Query: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG-KAGVQLEPQLE 431
+P EP T EP T PKEP P E P K P+
Sbjct: 447 TPKEPAPTTPKEP----------------TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 490
Query: 432 APLNEEMPLLPPPEESPLSPPPEESPTSPP---PEASRLSPPPEELPASPLPEALHLSRP 488
AP + P P+E + E SPT+P P ++ +P + PA P + P
Sbjct: 491 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTP 549
Query: 489 LEESPLSPP------PEESPLSPPPESSPFSPLEESPLSPPEESPPS---PALETPLSPP 539
E SP + P+E + P + +P +P E +P +P E +P + PA TP P
Sbjct: 550 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 609
Query: 540 PEASPLSPPFEESPLSPP-PEEL-PTSP----PPEASRLSPPPEESPMSPPPEESPMSPP 593
P + P L+P PE+L PT+P P L+P E P PEE P
Sbjct: 610 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE-PAPTT 668
Query: 594 PEASRLFPPFEESPLSP-------PPEESPLSPPPEA---------SRLSPPPEDSPMSP 637
P+A+ P E +P +P P E +P +P A + L P +P P
Sbjct: 669 PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 728
Query: 638 PPEE---SPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPEESPTSPPPEA-SRLSP 691
P+E + P + P P + + P P+E + P E +PT+P A + L
Sbjct: 729 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE 788
Query: 692 PPEDSPTSPPPE---------------DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736
P +P P P+ D PA P+++ + P E +P P P P
Sbjct: 789 PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT-P 847
Query: 737 RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL----SPQA 792
+ P S P + P H SP P LS +P L P+EP + +P A
Sbjct: 848 ETPPPTTS-EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 906
Query: 793 EGPHLSPQPEE------LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE------- 839
P ++ ++ L +P+T E + + ES ++ + +
Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 966
Query: 840 ------------PCLSPR----------------PEESHLSPE--LEKPPLSPRPEKPPE 869
L+P+ PEE+ + +P+P+KP +
Sbjct: 967 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 1026
Query: 870 EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927
P + + ++ P +P +P + + P P S + E + L + P+ +P
Sbjct: 1027 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAM-LQTTTRPNQTP 1083
Score = 130 bits (327), Expect = 4e-29
Identities = 169/750 (22%), Positives = 249/750 (33%), Gaps = 89/750 (11%)
Query: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPE------------ESPPSPALETPLSPPP 540
P++P P P S + + + +E+ + E + + A ET
Sbjct: 257 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 316
Query: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP--PPEESPMSPPPEASR 598
A L+P + P E T P L+ P E +P +P P +P P P +
Sbjct: 317 SAKDLAPTSKVLAKPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTPTTIK 372
Query: 599 LFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV 658
P + P + +P +P A + P + P + P P ++ +P
Sbjct: 373 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 432
Query: 659 VSRLSPPPEESPLSPPPEESPTSP--PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM 716
P++ + P E +PT+P P + P P +P PA P+
Sbjct: 433 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Query: 717 SLPLEESPLLP--------------LPEEPQLCPRSEGPHLS--PRPEEPHLSP-RPEEP 759
+ P E +P P P+EP P + P P +P P+EP
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552
Query: 760 HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819
SP + P+EP + +P+ P +P +P T + P
Sbjct: 553 --SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP-----APTTTKKPAPTTP 605
Query: 820 EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP-PLSPRPEKP--PEEPGQCPA 876
+EP + E + +P+ L+P E EKP P +P P PEEP
Sbjct: 606 KEPAPTTPKETAPTTPKK----LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 661
Query: 877 PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
E P P P+ EPA + P EP + E P +P +P+ P L
Sbjct: 662 EEPAPTTPKAAAPNTPK---EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 718
Query: 937 PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV 996
P AP L+P E P D P +P A T EP
Sbjct: 719 EPAPTTPKKPAPKELAPTTTKE-PTSTTCDK-----------PAPTTPKGTAPTTPKEPA 766
Query: 997 PPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLS 1056
P P+P +P G A L EP P L P + P + P+P +
Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK----GPTSTTSDKPAPTT 822
Query: 1057 PIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116
P E T K P P P TS ++S P + P S
Sbjct: 823 PKETAPTTPKEP---APTTPKKPAPTTPETPPPTTS-------EVSTPTTTKEPTTIHKS 872
Query: 1117 GLGEDTAPLDGIDAP----GSQPEPG----QTPGSLASELKGSPVLLDPEELAPVTPMEV 1168
E T L P S EPG +TP + E+ + E TP
Sbjct: 873 P-DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 931
Query: 1169 YPECKQTAGQGSPCEEQEEPRAPVAPTPPT 1198
K T + E+ E + T T
Sbjct: 932 TAAPKMTKETATTTEKTTESKITATTTQVT 961
Score = 97.1 bits (240), Expect = 4e-19
Identities = 165/754 (21%), Positives = 251/754 (33%), Gaps = 92/754 (12%)
Query: 507 PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP 566
P+ F +P SPP +PPP + + PP + T
Sbjct: 98 PDYESFCAEVHNPTSPPSSKK---------APPPSGASQTIKSTTKRSPKPPNKKKTKKV 148
Query: 567 PEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626
E+ ++ EE +S E S S +S + S S E + ++
Sbjct: 149 IESEEIT---EEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKK 205
Query: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS-----RLSPPPE---ESPLSPPPEES 678
+ + PP + S P S ++S P+ P++P P
Sbjct: 206 NRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP 265
Query: 679 PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
P S + + L+ E + + + + + +E+ + L P S
Sbjct: 266 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 325
Query: 739 EG-PHLSPRPEEPHLSPR---PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794
+ +P+ E P P+EP +P + S P+EP + P +
Sbjct: 326 KVLAKPTPKAETTTKGPALTTPKEP--TPTTPKEPASTTPKEPTPTTIKSAPTTPKE--- 380
Query: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS--PRPEESHLS 852
P P +P T P+EP + E + +P+ P + P P + +
Sbjct: 381 ----PAPTTTKSAPTT--------PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 428
Query: 853 PELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL-SPLLGEPALSEPGEP----P 907
P K P P+KP + PAP P P P P +P EPA + P EP P
Sbjct: 429 PTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 487
Query: 908 LSPLP----EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL---SPLGELEYP 960
P P E P +P EP+ + P P +P T +AP +P P
Sbjct: 488 KKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 546
Query: 961 FGAKGDSDPESPLAAPILE---TPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILM 1017
K S + AP P +P A T EP P P+P + PA
Sbjct: 547 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 606
Query: 1018 EPLPP---QCSPLLQHSLVPQNSPPSQCSPPALPL-SVPSPLSPIGKVVGVSDEAELHEM 1073
EP P + +P L P + P P + P L+P E
Sbjct: 607 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 666
Query: 1074 ETEKVSEPECPALEPSATSPL-PSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGID--- 1129
T K + P P EP+ T+P P+P + P+P + + TAP +
Sbjct: 667 TTPKAAAPNTPK-EPAPTTPKEPAPT---TPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 722
Query: 1130 -----------APGSQPEPGQT---------PGSLASELKGSPVLLDPEELAPVTPMEVY 1169
AP + EP T P A P P+E AP TP
Sbjct: 723 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 782
Query: 1170 PECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSD 1203
P + +P + + AP PT SD
Sbjct: 783 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 816
Score = 91.3 bits (225), Expect = 2e-17
Identities = 134/572 (23%), Positives = 197/572 (34%), Gaps = 63/572 (11%)
Query: 2108 PQPGALGSPPPAA---APTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDS---PGELFL 2161
P P + S P APT +PTTP + + P P P + P
Sbjct: 366 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 425
Query: 2162 KLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAG 2221
K P P + P AP P EP PT P P+PT P +P + P
Sbjct: 426 KSAPTTPKEPAPTTPKKPAPTTPKEP-----APTTPKEPTPT-TPKEP--APTTKEPAPT 477
Query: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGES 2281
P E T P P P+TP K P+ P+ P K P P +
Sbjct: 478 TPKEPAPTAPKKP--APTTP----KEPAPT-----TPKEPAPTTTKEPSPTTPKEPAPTT 526
Query: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTP-RASQVEP 2340
K+ +E A + + P SP++ K P AP TP + + P
Sbjct: 527 TKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP----APTTPKKPAPTTP 581
Query: 2341 QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP--PPESCCAL 2398
+ P P+EP P P+P T P P TP+ P P +
Sbjct: 582 KEPA-PTTPKEPAPTTTKKPAP------------TTPKEPAPTTPKETAPTTPKKLTPTT 628
Query: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP-PSRP 2457
P + P+ P P +P+ + + +P P P + E P+P TP+ +P+ P P+ P
Sbjct: 629 PEKLAPTTPEKPAPTTPE-ELAPTTPEEPTPTTPEE--PAPTTPKAAAPNTPKEPAPTTP 685
Query: 2458 QSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPN 2517
+ P P K P P P+ A T+ G P L P P
Sbjct: 686 KEPAPTTP--KEPAPTTPK------ETAPTT-PKGTAPTTLKEPAPTTPKKPAPKELAPT 736
Query: 2518 FVRSP-GTGAFVGTPSPMRFTFPQAVGEPS-LKPPVPQPGLPPPHGINSHFGPGPTLGKP 2575
+ P T P+ + T P EP+ P P P P + P PT K
Sbjct: 737 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 796
Query: 2576 QSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQR 2635
+ T P+ + + +T + + + P+ P P + P +
Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-- 854
Query: 2636 SGITSPVEKREDPGTGMGSSLATAELPGTQDP 2667
S +++P +E +T EL P
Sbjct: 855 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 886
Score = 63.5 bits (153), Expect = 5e-09
Identities = 91/385 (23%), Positives = 134/385 (34%), Gaps = 57/385 (14%)
Query: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQV 2167
P+ A +P A T +PTTP + + P P P +P E P
Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET----APTT 620
Query: 2168 PAQVPSQDPFGLAPAYPLEPRFPTAP----PTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223
P ++ P LAP P +P PT P PT P P+PT P +P A + P A P
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPA-PTTPEELAPTTPEEPTPT-TPEEP----APTTPKAAAP 674
Query: 2224 GEFHTTPPGTPRHQ-PSTPDPFLKPRCPSLDNLAVPESP-GVGGGKASEPLLSPPPFGES 2281
P TP+ P+TP K P+ P +P G EP + P
Sbjct: 675 NTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730
Query: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ 2341
++ +E +++ P +P++ K P AP TP+ +
Sbjct: 731 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP----APTTPKGTAPTTL 786
Query: 2342 SPGLGLRPQEPPPAQAL---------------APSPPSH--PDIFRPGSYTDPYAQPPLT 2384
P++P P + AP+ P P + + T P P T
Sbjct: 787 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 846
Query: 2385 PRPQPPPPESCCALP-----PRSLPSDPFSRVP---ASPQSQSSSQSPLTPRPLSAEAFC 2436
P PPP S + P P ++ P P A P ++ SP P
Sbjct: 847 PE-TPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG-------V 898
Query: 2437 PSPVTPRFQSPDPYSRPPSRPQSRD 2461
P+ TP P+ + + RD
Sbjct: 899 PTTKTPAATKPEMTTTAKDKTTERD 923
Score = 53.9 bits (128), Expect = 4e-06
Identities = 94/455 (20%), Positives = 143/455 (31%), Gaps = 52/455 (11%)
Query: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPL-LSPPPFGESRKALEVKKEE 2291
TP+ + +T P L P P+ P K P + P A K
Sbjct: 332 TPKAETTTKGPALTT--PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS- 388
Query: 2292 LGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE 2351
++P P +P++ K P AP T +++ P+ P P++
Sbjct: 389 -APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEP----APTTTKSAPTTPKEPA-PTTPKK 442
Query: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPR-PQPPPPESCCALPPRSLPSDPFSR 2410
P P P+P T P P TP+ P P E P P+ P
Sbjct: 443 PAPTTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 490
Query: 2411 VPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP 2470
P +P+ + + +P P P + + PSP TP+ +P P+ + P P
Sbjct: 491 APTTPKEPAPT-TPKEPAPTTTKE--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 547
Query: 2471 RPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP-PNFVRSPG------ 2523
P+ P T PA + A +P P + P
Sbjct: 548 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 607
Query: 2524 ------TGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTL-GKPQ 2576
TP + T P+ + + P P P P + P PT +P
Sbjct: 608 PAPTTPKETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEEPA 665
Query: 2577 STNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP----PPAPDGSLPYLSHGA 2632
T A N +P P+ + E +P P P P P G+ P
Sbjct: 666 PTTPKAAAPN-----TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 720
Query: 2633 SQRSGITSPVEKREDPGTGMGSSLATAELPGTQDP 2667
+ + P K P T + T + P P
Sbjct: 721 APTTP-KKPAPKELAPTTTKEPTSTTCDKPAPTTP 754
Score = 49.3 bits (116), Expect = 1e-04
Identities = 83/387 (21%), Positives = 117/387 (30%), Gaps = 50/387 (12%)
Query: 4601 PTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARD 4660
PT P S TK P P+ P P K TP E K A
Sbjct: 546 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 605
Query: 4661 SERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPE---SILGE 4717
E A E PT P +P+ + P + E + E
Sbjct: 606 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTT--PEKPAPTTPEELAPTTPEEPTPTTPEE 663
Query: 4718 EAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFP-DTKPYGALGLEVPGKLPVTTWEK 4776
AP P + +E +P P P + P P T P G P T E
Sbjct: 664 PAPTTPKAAAPNTPKEP---APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 720
Query: 4777 GKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAE 4836
T A K L + K P S P GT P +
Sbjct: 721 AP-------TTPKKPAPKELAPT--------TTKEPTSTTCDKPAPTTPKGTAPTTPKEP 765
Query: 4837 GPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSL-----LKQESPAPEPPTQ 4891
P ++ T P LK+ P +L + + PAP P
Sbjct: 766 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-- 823
Query: 4892 HSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPS--P 4949
++ + P+EP+ P +P P+P +P T P PT P + P
Sbjct: 824 ------------KETAPTTPKEPA-PTTPKKPAPTTPETPP----PTTSEVSTPTTTKEP 866
Query: 4950 LPLASSPESARPKPRARPPEEGEDSRP 4976
+ SP+ + P+ A P + ++ P
Sbjct: 867 TTIHKSPDESTPELSAEPTPKALENSP 893
Score = 47.0 bits (110), Expect = 5e-04
Identities = 82/383 (21%), Positives = 115/383 (30%), Gaps = 35/383 (9%)
Query: 4612 TKNNLSNPPTPPSSLPPTPPPSVQQ--KMVNGVTPSEELGEHPKDAASARDSERALRDTS 4669
T + + PT P PT S K T E PK+ A E A T
Sbjct: 367 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 426
Query: 4670 EVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGR 4729
+ A PT P E + + P E AP P +
Sbjct: 427 SAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 485
Query: 4730 WEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPG-----KLPVTTWEKGKGSEVSV 4784
++ +P P P TK + P P TT E + S
Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545
Query: 4785 MLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKG 4844
T + + + P P+ PA T PK+ P +K
Sbjct: 546 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKE---PAPTTTKKP 600
Query: 4845 LEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVR 4904
+ P K+ P + + L+ E PAP P
Sbjct: 601 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP--------------E 646
Query: 4905 QLSAPPPEEPSPP----PSPLAPSPASP--PTEPLVELPTEPLAEPPVPSPLPLASSPES 4958
+L+ PEEP+P P+P P A+P P EP P EP P P + E+
Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP--APTTPKEPAPTTPKET 704
Query: 4959 ARPKPRARPPEEGEDSRPPRLKK 4981
A P+ P ++ P KK
Sbjct: 705 APTTPKGTAPTTLKEPAPTTPKK 727
Score = 42.7 bits (99), Expect = 0.010
Identities = 84/389 (21%), Positives = 128/389 (32%), Gaps = 47/389 (12%)
Query: 4604 PDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSER 4663
PDY S + NP +PPSS PPPS + + T + K +SE
Sbjct: 98 PDYESFCA---EVHNPTSPPSS-KKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEE 153
Query: 4664 ALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPA--SSPESILGEEAPR 4721
T H+ +E+ S S S S + SS S E +
Sbjct: 154 I-----------------TEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQK 196
Query: 4722 FPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSE 4781
+ + + + +P P++ A GL+ G VTT +
Sbjct: 197 KLKVKDNKKNRTKKKPTPKPPVVDEAGS------------GLD-NGDFKVTTPDTSTTQH 243
Query: 4782 VSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGK 4841
V + AK +N + K + + E+ + GK
Sbjct: 244 NKVSTSPKITTAKPINPRPSLPPNSDTSK--ETSLTVNKETTVETKETTTTNKQTSTDGK 301
Query: 4842 EKGLEGKSPD----TGPDWLKQFDAVLPGYTLKSQLDIL--SLLKQESPAPEPPTQHSYT 4895
EK K T L VL T K++ +L + P P P + + T
Sbjct: 302 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST 361
Query: 4896 YNVSNLDVRQLSAPP-PEEPSPPPSPLAP-SPASP-PTEPLVELPTEPLAEPPVPSPLPL 4952
SAP P+EP+P + AP +P P PT PT P P + P
Sbjct: 362 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA 421
Query: 4953 ASSPESARPKPRARPPEEGEDSRPPRLKK 4981
++ +SA P+ P + P K+
Sbjct: 422 PTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450
Score = 40.8 bits (94), Expect = 0.038
Identities = 112/590 (18%), Positives = 185/590 (31%), Gaps = 66/590 (11%)
Query: 3999 PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESM 4058
P P KP ++P PT T KE P + T+ P+ A +
Sbjct: 437 PTTPKKPAP--TTPKEPAPT---TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491
Query: 4059 ATEPGEVKPSLSGD-SQLLLVQPQP----QPQPSSLQLQPPLRLPGQQQQQVSLLHTAGG 4113
T P E P+ + + +P P +P P++ + P T
Sbjct: 492 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT---------------TTKE 536
Query: 4114 GSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPP 4173
+ S ++ P +P+ + +P T P P P T P+ P
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP----TTPKEP 592
Query: 4174 KPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQ 4233
P + P PT + A L+P ++ A +L
Sbjct: 593 APTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEELAP 650
Query: 4234 SQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP--PRLPA 4291
+ TP E T+P P P P T P + P+ P P+ A
Sbjct: 651 TTPEEPTPTTPEEPAPTTPK----AAAPNTPKEPAPTT-PKEPAPTTPKEPAPTTPKETA 705
Query: 4292 PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTL 4351
P T P P P++P++P P +L +++ PT P TPK PT
Sbjct: 706 PTTPKGTAPT---TLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 761
Query: 4352 EPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAET-QKPEQSSLVPGHLDQVNGQVVPEA 4410
P +P + A T KG P + T +KP L P +
Sbjct: 762 PKEPAPTTP--KEPAPTT-PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 818
Query: 4411 SQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAK 4470
+ + K+ P + K+ A P P T++ + E
Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE------------- 865
Query: 4471 NVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPK-----RV 4525
+ + + E++ K K G P+ K AA + +T K R
Sbjct: 866 --PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 923
Query: 4526 QKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSL 4575
+ + ++ K+ KE + ++ + + T T F +
Sbjct: 924 LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 973
Score = 40.8 bits (94), Expect = 0.038
Identities = 84/369 (22%), Positives = 108/369 (29%), Gaps = 49/369 (13%)
Query: 4620 PTPPSSLPPTP--PPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLL 4677
PT S P TP P K TP E PK A E A E
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 598
Query: 4678 AALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRAL 4737
PT P E+ + P + P ++PE + AP P + +E L
Sbjct: 599 KPAPTTPKEPAPTTPKETAPTT--PKKLTP-TTPEKL----APTTPEKPAPTTPEE---L 648
Query: 4738 SPVIPLIPRASIPVFP-DTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNL 4796
+P P P + P P T P A P T E + T A
Sbjct: 649 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 708
Query: 4797 NGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDW 4856
L P + P+ PA P + +K T P
Sbjct: 709 PKGTAPTT--LKEPAPTT-----PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 761
Query: 4857 LKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSP 4916
K+ P + PAP P + T L P P P
Sbjct: 762 PKEPAPTTP----------------KEPAPTTPKGTAPT---------TLKEPAPTTPKK 796
Query: 4917 P-PSPLAPSPASPPTEPLVE--LPTEPLAEPPVPSPLPLASSPESARP-KPRARPPEEGE 4972
P P LAP+ PT + PT P P P ++P+ P P PP E
Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 856
Query: 4973 DSRPPRLKK 4981
S P K+
Sbjct: 857 VSTPTTTKE 865
Score = 38.1 bits (87), Expect = 0.24
Identities = 34/123 (27%), Positives = 44/123 (35%), Gaps = 13/123 (10%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP--PRLPAPPGALS 4297
TP P T P P P P T P + P+ P P+ P P +
Sbjct: 408 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPTP----T 462
Query: 4298 TGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR 4357
T P P P++P+EP + P PT + P P TPK PT P
Sbjct: 463 TPKEPAPTTKEPAPTTPKEPAPTA----PKKPAPTTPKEPA--PTTPKEPAPTTTKEPSP 516
Query: 4358 VSP 4360
+P
Sbjct: 517 TTP 519
Score = 36.6 bits (83), Expect = 0.71
Identities = 57/296 (19%), Positives = 104/296 (35%), Gaps = 24/296 (8%)
Query: 4067 PSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSE 4126
P SG SQ + + P+P + + + + ++++ H+ S SSS
Sbjct: 120 PPPSGASQTIKSTTKRSPKPPNKKKTKKVI----ESEEITEEHSVSENQESSSSSSSSSS 175
Query: 4127 ASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQP-PKPGPVLQSGQGL 4185
+S++ + + + + + + ++ +N T +P PKP V ++G GL
Sbjct: 176 SSTIRKIKSSKNSAANRELQKKLK---------VKDNKKNRTKKKPTPKPPVVDEAGSGL 226
Query: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245
T ++ +P++ P + + S V + +
Sbjct: 227 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 286
Query: 4246 PGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPV 4305
T T+ Q + + +T +++ A L P T GP
Sbjct: 287 KETTTTNKQTSTDGKEKTTS--AKETQSIEKTSAKDLAPTSKVLAKPTPKAET-TTKGPA 343
Query: 4306 HPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP----QGPTL--EPPP 4355
TP +P PK P+ +P PT + PT P P P PT EP P
Sbjct: 344 LTTPKEPTPTTPKEPAS-TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP 398
Score = 34.7 bits (78), Expect = 2.7
Identities = 36/126 (28%), Positives = 44/126 (34%), Gaps = 8/126 (6%)
Query: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPP--RLPAPPGALS 4297
TP T P + P P P T + P+ P + PAP
Sbjct: 354 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT--TKSAPTTPKEPAPTTTKEPAPTTPKE 411
Query: 4298 TGPVLGPVH-PTPPPSSPQEPKRPSQLPSPSSQLPTEAQLP-PTHPGTPKPQGPTLEPPP 4355
P PT S+P PK P+ +P PT + P PT P P P P EP P
Sbjct: 412 PAPTTTKEPAPTTTKSAPTTPKEPAP-TTPKKPAPTTPKEPAPTTPKEPTPTTPK-EPAP 469
Query: 4356 GRVSPA 4361
PA
Sbjct: 470 TTKEPA 475
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 144 bits (362), Expect = 3e-33
Identities = 104/349 (29%), Positives = 130/349 (37%), Gaps = 54/349 (15%)
Query: 436 EEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLS 495
EE P L SP P PP PP P P P+ P
Sbjct: 26 EESPSLIAGNPQGPSPQGGNKPQGPP--------PPPGKPQGPPPQG-------GNKPQG 70
Query: 496 PPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE--ESP 553
PPP P PPP+ S SP P+ PP + PPP P PP + P
Sbjct: 71 PPPPGKPQGPPPQGDK-SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRP 129
Query: 554 LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE 613
PPP P PPP+ + SP SPP + P PPP+ + PPP
Sbjct: 130 QGPPPPGKPQGPPPQGDK-----SRSPRSPPGK--PQGPPPQGG------NQPQGPPPPP 176
Query: 614 ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673
P PPP+ + P PPP P PPP+ + SR S P P P
Sbjct: 177 GKPQGPPPQGGK-------KPQGPPPPGKPQGPPPQGDK-------SRSSQSPPGKPQGP 222
Query: 674 PPE--ESPTSPPPEASR-LSPPPE--DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL 728
PP+ P PPP + PPP+ + P PPP P PP + S P P
Sbjct: 223 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQ 282
Query: 729 --PEEPQLCPRSEGPHLSPRPEEPHLSP--RPEEPHLSPQAEEPHLSPQ 773
P++ P+ P P++P P +P+ P PQ P PQ
Sbjct: 283 GPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 132 bits (331), Expect = 1e-29
Identities = 103/335 (30%), Positives = 124/335 (37%), Gaps = 67/335 (20%)
Query: 406 PKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPE----------- 454
P+ P P Q KP G +PQ P P PPP P PPP+
Sbjct: 36 PQGPSP-QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP 94
Query: 455 ESPTSPPPEASRL---SPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSP 511
P PPP+ PPP P P P+ P PPP P PPP+
Sbjct: 95 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG-------GNRPQGPPPPGKPQGPPPQGDK 147
Query: 512 FSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE--ESPLSPPPEELPTSPPPEA 569
S SP P+ PP + PPP P PP + + P PPP P PPP+
Sbjct: 148 -SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQG 206
Query: 570 --SRLSPPPEESPMSPPPE--ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASR 625
SR S P P PPP+ P P PPP P PPP+
Sbjct: 207 DKSRSSQSPPGKPQGPPPQGGNQPQGP-----------------PPPPGKPQGPPPQGG- 248
Query: 626 LSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEE--SPTSPP 683
+ P PPP P PP + S S SPP + P PP +E +P PP
Sbjct: 249 ------NKPQGPPPPGKPQGPPAQGGSKSQ----SARSPPGK--PQGPPQQEGNNPQGPP 296
Query: 684 PEA----SRLSPPPEDSPTSP--PPEDSPASPPPE 712
P A + PP P P PP+ S PP+
Sbjct: 297 PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 119 bits (299), Expect = 6e-26
Identities = 102/346 (29%), Positives = 129/346 (37%), Gaps = 63/346 (18%)
Query: 524 EESPPSPALETPLSPPPEAS--PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPM 581
+E PS P P P+ P PP PP P PPP+ P
Sbjct: 25 QEESPSLIAGNPQGPSPQGGNKPQGPP--------PPPGKPQGPPPQGGN-------KPQ 69
Query: 582 SPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL---SPPPEDSPMSPP 638
PPP P PPP+ + SP SPP + P PPP+ PPP P PP
Sbjct: 70 GPPPPGKPQGPPPQGDK-----SRSPRSPPGK--PQGPPPQGGNQPQGPPPPPGKPQGPP 122
Query: 639 PE--ESPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPE--ESPTSPPPEASR-LSP 691
P+ P PPP P P + P P P PPP+ P PPP + P
Sbjct: 123 PQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 182
Query: 692 PPE--DSPTSPPPEDSPASPPPE-DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE 748
PP+ P PPP P PPP+ D S +SP P +PQ P P+
Sbjct: 183 PPQGGKKPQGPPPPGKPQGPPPQGDKSRS---SQSP----PGKPQ----------GPPPQ 225
Query: 749 EPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP-----HLSPQAEGPHLSPQ--P 801
+ P P PQ P +P+ P P+ P S A P PQ P
Sbjct: 226 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPP 285
Query: 802 EELHLSPQTEEPHLSPVPEEPCLSP--QPEESHLSPQSEEPCLSPR 845
++ +PQ P P++P P QP+ PQ P P+
Sbjct: 286 QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 110 bits (274), Expect = 5e-23
Identities = 90/330 (27%), Positives = 117/330 (35%), Gaps = 56/330 (16%)
Query: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621
P P P+ P PPP P PPP+ P PPP P PPP
Sbjct: 36 PQGPSPQGGNKPQGP------PPPPGKPQGPPPQGGN-------KPQGPPPPGKPQGPPP 82
Query: 622 EASRLSPP--PEDSPMSPPPE--ESPMSPPPEVSRLSPLPVVSRLSPPPE--ESPLSPPP 675
+ + P P P PPP+ P PPP P PPP+ P PPP
Sbjct: 83 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP--------PPGKPQGPPPQGGNRPQGPPP 134
Query: 676 EESPTSPPPEASRLSPP--PEDSPTSPPPE--DSPASPPPEDSLMSLPLEESPLLPLPEE 731
P PPP+ + P P P PPP+ + P PPP P P
Sbjct: 135 PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP-----------PPGKPQGPP 183
Query: 732 PQLCPRSEGPHLSPRPEEP----HLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPH 787
PQ + +GP +P+ P S + P PQ P QP+ P P +P
Sbjct: 184 PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP--PPPPGKPQ 241
Query: 788 -LSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQ--PEESHLSPQSEEPCLSP 844
PQ P P P + S P PQ P++ +PQ P
Sbjct: 242 GPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG 301
Query: 845 RPEESHLSPELE-----KPPLSPRPEKPPE 869
P++ P + +PP RP +PP+
Sbjct: 302 NPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 87.0 bits (214), Expect = 5e-16
Identities = 92/304 (30%), Positives = 111/304 (36%), Gaps = 56/304 (18%)
Query: 2335 ASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPES 2394
A + SP G +PQ PPP PP P P P PP +PQ PPP+
Sbjct: 33 AGNPQGPSPQGGNKPQGPPP-------PPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQG 84
Query: 2395 CCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSR-- 2452
+ PRS P P P Q +Q P P P R Q P P +
Sbjct: 85 DKSRSPRSPPGK-----PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQ 139
Query: 2453 --PPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKV 2510
PP +SR P +P KP P P GG P P G+
Sbjct: 140 GPPPQGDKSRSPRSPPGKPQGPPP----------------QGGNQPQGPPPPPGK----- 178
Query: 2511 PSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP--SLKPPVPQPGLPPPHGINSHFGP 2568
P G PP + P G P P + P G+ S + P +P PPP G N GP
Sbjct: 179 PQGPPPQGGKKP-----QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP 233
Query: 2569 GPTLGKPQSTNYTVATGNF----HPSGSPLGP--SSGSTGESYGLSPLRPPSVLPPPAPD 2622
P GKPQ GN P G P GP GS +S P +P PP +
Sbjct: 234 PPPPGKPQGP--PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQG---PPQQE 288
Query: 2623 GSLP 2626
G+ P
Sbjct: 289 GNNP 292
Score = 84.0 bits (206), Expect = 4e-15
Identities = 92/326 (28%), Positives = 119/326 (36%), Gaps = 53/326 (16%)
Query: 669 SPLSPPPE--ESPTSPPPEASR-LSPPPE--DSPTSPPPEDSPASPPPEDSLMSLPLEES 723
+P P P+ P PPP + PPP+ + P PPP P PPP+ P
Sbjct: 35 NPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP-RSP 93
Query: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ--PEEPCLCA 781
P P PQ + +GP P P +P P P+ + PQ P PQ P +
Sbjct: 94 PGKPQGPPPQGGNQPQGP--PPPPGKPQ-GPPPQGGN-RPQGPPPPGKPQGPPPQGDKSR 149
Query: 782 VPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQ--PEESHLSPQSEE 839
P P PQ P QP+ P P PQ P + PQ
Sbjct: 150 SPRSPPGKPQGPPPQGGNQPQG---------------PPPPPGKPQGPPPQGGKKPQGPP 194
Query: 840 PCLSPR--PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897
P P+ P + S + PP +P+ PP + G P PPPG+P P G
Sbjct: 195 PPGKPQGPPPQGDKSRSSQSPP--GKPQGPPPQGGNQPQGPP----PPPGKPQGPPPQGG 248
Query: 898 PALSEPGEPPLSPLPEELPL----------SPSGEPSLSPQL---MPPDPLPPPLSPIIT 944
++P PP P+ P SP G+P PQ P P PP
Sbjct: 249 ---NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 305
Query: 945 AAAPPALSPLGELEYPFGAKGDSDPE 970
APPA P G P G + P+
Sbjct: 306 PQAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 80.5 bits (197), Expect = 4e-14
Identities = 91/354 (25%), Positives = 124/354 (35%), Gaps = 72/354 (20%)
Query: 678 SPTSPPPEASRLS---PPPEDSPTSPPPE--DSPASPPPEDSLMSLPLEESPLLPLPEEP 732
+P P P+ PPP P PPP+ + P PPP P +P
Sbjct: 35 NPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP-----------------PGKP 77
Query: 733 QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA 792
Q GP P + S P P PQ P QP+ P P
Sbjct: 78 Q------GP-----PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP------------PPP 114
Query: 793 EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLS 852
G P P+ P P P +P P + SP+S P +
Sbjct: 115 PGKPQGPPPQG------GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 168
Query: 853 PELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLP 912
P+ PP +P+ PP + G+ P PPPG+P P G+ + S S P
Sbjct: 169 PQGPPPPPG-KPQGPPPQGGKKPQGP-----PPPGKPQGPPPQGDKSRS-------SQSP 215
Query: 913 EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESP 972
P P + PQ PP P P P P P G+ + P A+G S +S
Sbjct: 216 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-PAQGGSKSQSA 274
Query: 973 LAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSP 1026
+ P PP+ +P+ PP P+ G+P P +P +P P P
Sbjct: 275 RSPP---GKPQGPPQQEGNNPQGPPP----PAGGNPQQPQAPPAGQPQGPPRPP 321
Score = 79.7 bits (195), Expect = 7e-14
Identities = 97/361 (26%), Positives = 118/361 (32%), Gaps = 71/361 (19%)
Query: 2258 PESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLG 2317
P+ P GG ++P PPP G+ + G + P GPP G P
Sbjct: 36 PQGPSPQGG--NKPQGPPPPPGKPQGP-----PPQGGNKPQ-GPPPPGKPQGPPP----- 82
Query: 2318 GLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDP 2377
D ++P +P P G G +PQ PPP PP P P P
Sbjct: 83 -----QGDKSRSPRSPPGKPQGPPPQG-GNQPQGPPP-------PPGKPQGPPPQGGNRP 129
Query: 2378 YAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCP 2437
PP +PQ PPP+ + PRS P P P Q +Q P P P
Sbjct: 130 QGPPP-PGKPQGPPPQGDKSRSPRSPPGKP-----QGPPPQGGNQPQGPPPPPGKPQGPP 183
Query: 2438 SPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP-RPQPPEVAFKAGSLAHTSLGAGGFPA 2496
+ Q P P +P P D PP +PQ P GG
Sbjct: 184 PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQ-------------GGNQP 230
Query: 2497 ALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVG----EPSLKPPVP 2552
P P G+ P G PP P G P P + P A G + + PP
Sbjct: 231 QGPPPPPGK-----PQGPPPQGGNKPQ-----GPPPPGKPQGPPAQGGSKSQSARSPPGK 280
Query: 2553 QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRP 2612
G P G N P P G PQ P P G G G P RP
Sbjct: 281 PQGPPQQEGNNPQGPPPPAGGNPQ-----------QPQAPPAGQPQGPPRPPQGGRPSRP 329
Query: 2613 P 2613
P
Sbjct: 330 P 330
Score = 77.0 bits (188), Expect = 5e-13
Identities = 91/321 (28%), Positives = 108/321 (33%), Gaps = 49/321 (15%)
Query: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTY----PPYPSPTGAPAQPPMLGASSRPGA 2220
PQ P+ P G P P P PP P P P G P PP G SR
Sbjct: 36 PQGPSPQGGNKPQGPPPP----PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91
Query: 2221 GQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE 2280
PG+ PP P P KP+ P P GG + P PPP
Sbjct: 92 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGP----------PPQGGNRPQGP---PPPGKP 138
Query: 2281 SRKALEVKKEELGASSPS--YGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQV 2338
+ K S P GPP P G G P K P
Sbjct: 139 QGPPPQGDKSRSPRSPPGKPQGPP-------PQGGNQPQG---PPPPPGKPQGPPPQGGK 188
Query: 2339 EPQSPGLGLRPQEPPP---AQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPE-- 2393
+PQ P +PQ PPP + SPP P P P PP +PQ PPP+
Sbjct: 189 KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 248
Query: 2394 -SCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR-PLSAEAFCPSPVTPRFQSPDPYS 2451
PP P P ++ +SQS+ P P+ P E P P P
Sbjct: 249 NKPQGPPPPGKPQGPPAQ--GGSKSQSARSPPGKPQGPPQQEGNNPQ------GPPPPAG 300
Query: 2452 RPPSRPQSRDPFAPLHKPPRP 2472
P +PQ+ P PPRP
Sbjct: 301 GNPQQPQA-PPAGQPQGPPRP 320
Score = 70.5 bits (171), Expect = 4e-11
Identities = 85/295 (28%), Positives = 112/295 (37%), Gaps = 22/295 (7%)
Query: 773 QPEEPCLCAV-PEEPHLSPQAEG-PHLSPQPEELHLSPQTE---EPHLSPVPEEPCLSPQ 827
Q E P L A P+ P SPQ P P P P + +P P P +P P
Sbjct: 25 QEESPSLIAGNPQGP--SPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82
Query: 828 PEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG---QCPAPEELPLFP 884
+ SP+S P + P+ PP +P+ PP + G Q P P P P
Sbjct: 83 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG-KPQGPPPQGGNRPQGPPPPGKPQGP 141
Query: 885 PP-GEPSLSPLL--GEPALSEP---GEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPP 938
PP G+ S SP G+P P +P P P P P + PQ PP P P
Sbjct: 142 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQ-GPPPPGKPQ 200
Query: 939 LSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPP 998
P + + SP G+ + P +G + P+ P P P PPP+ P+ PP
Sbjct: 201 GPPPQGDKSRSSQSPPGKPQGP-PPQGGNQPQGPPPPP--GKPQGPPPQGG-NKPQGPPP 256
Query: 999 MILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPS 1053
P P + G S P P Q PQ PP P P + P+
Sbjct: 257 PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA 311
Score = 69.3 bits (168), Expect = 1e-10
Identities = 103/375 (27%), Positives = 125/375 (33%), Gaps = 92/375 (24%)
Query: 2197 PPYPSPTGA--PAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPR--CPSL 2252
P PSP G P PP P G+P PP ++P P P KP+ P
Sbjct: 36 PQGPSPQGGNKPQGPP-------PPPGKP----QGPPPQGGNKPQGPPPPGKPQGPPPQG 84
Query: 2253 DNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSS 2312
D P SP GK PPP G + P PP G P
Sbjct: 85 DKSRSPRSP---PGKPQ----GPPP--------------QGGNQPQGPPPPPGKPQGP-- 121
Query: 2313 GTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPA--QALAP-SPPSHPDIF 2369
P PQ P +PQ PPP ++ +P SPP P
Sbjct: 122 --------------------PPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 161
Query: 2370 RPGSYTDPYAQPPLTPRPQPPPPE---SCCALPPRSLPSDPFSRVPASPQSQSSSQSPLT 2426
P P PP +PQ PPP+ PP P P + S SQS P
Sbjct: 162 PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQG 221
Query: 2427 PRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAH 2486
P P + Q P P PP +PQ P +KP P PP +
Sbjct: 222 PPPQGGN---------QPQGPPP---PPGKPQGPPPQGG-NKPQGPPPPGKPQGPPAQGG 268
Query: 2487 TSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPS 2546
+ + P P GP + P G PP P G +P + P A G+P
Sbjct: 269 SKSQSARSPPGKPQGPP-QQEGNNPQGPPP-----PAGG------NPQQPQAPPA-GQPQ 315
Query: 2547 LKPPVPQPGLP--PP 2559
P PQ G P PP
Sbjct: 316 GPPRPPQGGRPSRPP 330
Score = 63.9 bits (154), Expect = 4e-09
Identities = 88/311 (28%), Positives = 101/311 (32%), Gaps = 74/311 (23%)
Query: 2091 GDIARKTDRPALHLRIPPQPGA---LGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPA 2147
GD +R P + PP G G PPP P G P P G + PP
Sbjct: 84 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ---GPP--PQGGNRPQG---PPPP 135
Query: 2148 GSVPGPDSPGELFL--KLPPQVPAQVPSQDPFGLAP-AYPLEPRFPTAPPTY----PPYP 2200
G GP G+ + PP P P Q G P P P P PP P P
Sbjct: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGKKPQGP 193
Query: 2201 SPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPES 2260
P G P PP G SR PG+ PP P P KP+ P
Sbjct: 194 PPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP---------- 243
Query: 2261 PGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLE 2320
P GG K PPP G+ + GPP G S S+
Sbjct: 244 PPQGGNKPQ----GPPPPGKPQ-----------------GPPAQGGSKSQSA-------- 274
Query: 2321 LKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ 2380
++P P Q PQ G PQ PPP P P P P +
Sbjct: 275 -RSP--------PGKPQGPPQQE--GNNPQGPPPPAGGNPQQPQAP----PAGQPQGPPR 319
Query: 2381 PPLTPRPQPPP 2391
PP RP PP
Sbjct: 320 PPQGGRPSRPP 330
Score = 61.6 bits (148), Expect = 2e-08
Identities = 79/284 (27%), Positives = 97/284 (34%), Gaps = 47/284 (16%)
Query: 2387 PQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS 2446
PQ P P+ P+ P P PQ + Q P P P P Q
Sbjct: 36 PQGPSPQG--GNKPQGPPPPPGKPQGPPPQGGNKPQGP------------PPPGKP--QG 79
Query: 2447 PDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPA----GP 2502
P PP +SR P +P KP P P + G+ G P P P
Sbjct: 80 P-----PPQGDKSRSPRSPPGKPQGPPP-----QGGNQPQGPPPPPGKPQGPPPQGGNRP 129
Query: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP-QPGLPPPHG 2561
G P G PP +S + G P PQ +P PP P +P PPP G
Sbjct: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGPPPQG 186
Query: 2562 INSHFGPGPTLGKPQS--TNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPP 2619
GP P GKPQ + + P G P GP G P PP PP
Sbjct: 187 GKKPQGPPPP-GKPQGPPPQGDKSRSSQSPPGKPQGPPPQG-----GNQPQGPPP--PPG 238
Query: 2620 APDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPG 2663
P G P G ++ G P + + P G S + PG
Sbjct: 239 KPQGPPP---QGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG 279
Score = 59.3 bits (142), Expect = 1e-07
Identities = 84/291 (28%), Positives = 95/291 (32%), Gaps = 37/291 (12%)
Query: 2492 GGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPV 2551
GG P P G+ P G PP P G P P + P G+ S P
Sbjct: 43 GGNKPQGPPPPPGK-----PQGPPPQGGNKPQ-----GPPPPGKPQGPPPQGDKSRSPRS 92
Query: 2552 P--QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSP 2609
P +P PPP G N GP P GKPQ G P G P P G
Sbjct: 93 PPGKPQGPPPQGGNQPQGPPPPPGKPQG---PPPQGGNRPQGPP-PPGKPQGPPPQGDKS 148
Query: 2610 LRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPG-TQDPG 2668
P S PP P G P G +Q G P K + P G PG Q P
Sbjct: 149 RSPRS--PPGKPQGPPP---QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP 203
Query: 2669 MSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPA 2728
G +K R Q Q Q + GPP G +P P
Sbjct: 204 PQG------DKSRSSQSPPGKPQGPPPQGG--NQPQGPPPPPGKPQGPPPQGGNKPQGP- 254
Query: 2729 FEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPA 2779
+ Q P A KS PP K GP G+ P PPPPA
Sbjct: 255 -PPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG-----PPPPA 299
Score = 58.5 bits (140), Expect = 2e-07
Identities = 89/340 (26%), Positives = 117/340 (34%), Gaps = 58/340 (17%)
Query: 856 EKPPL-SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEE 914
E P L + P+ P + G P PPPG+P P G ++P PP P+
Sbjct: 27 ESPSLIAGNPQGPSPQGGNKPQGPP----PPPGKPQGPPPQGG---NKPQGPPPPGKPQG 79
Query: 915 LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLA 974
P P G+ S SP+ P P PP PP P G+ + P +G + P+ P
Sbjct: 80 PP--PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP--PPGKPQGP-PPQGGNRPQGP-- 132
Query: 975 APILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVP 1034
P P PPP+ + + PP G P GP +P P P P
Sbjct: 133 -PPPGKPQGPPPQGDKSRSPRSPP-------GKPQGPPPQGGNQPQGPPPPP-----GKP 179
Query: 1035 QNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL 1094
Q PP P P P P P G + +K + P +P
Sbjct: 180 QGPPPQGGKKPQGP---PPPGKPQGP-----------PPQGDKSRSSQSPPGKPQG---- 221
Query: 1095 PSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVL 1154
P P G P P P P G + P P PG+ G A S
Sbjct: 222 PPPQGGNQPQGPPPPPG-------KPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSA 274
Query: 1155 LDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAP 1194
P P P + P+ + QG P P+ P AP
Sbjct: 275 RSP----PGKP-QGPPQQEGNNPQGPPPPAGGNPQQPQAP 309
Score = 57.4 bits (137), Expect = 4e-07
Identities = 111/437 (25%), Positives = 125/437 (28%), Gaps = 148/437 (33%)
Query: 2545 PSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGES 2604
PSL PQ P P G N GP P GKPQ G P P G+
Sbjct: 29 PSLIAGNPQG--PSPQGGNKPQGPPPPPGKPQ--------------GPP--PQGGN---- 66
Query: 2605 YGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGT 2664
P PP PP P G P G RS + P + + P G PG
Sbjct: 67 ---KPQGPP---PPGKPQGPPP---QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 117
Query: 2665 QDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEP 2724
GPP G P
Sbjct: 118 PQ------------------------------------------------GPPPQGGNRP 129
Query: 2725 SSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSM 2784
P +G P DKS PP K GP G+ P PPPP P
Sbjct: 130 QGPPPPGKPQGPPPQG---DKSRSPRSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGP 182
Query: 2785 DVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPE 2844
GG + Q P PG Q + Q+ P P P+
Sbjct: 183 PPQ-----GGKKP--QGPPPPGKPQGPPPQGDKSRSSQSPPGK----------PQGPPPQ 225
Query: 2845 LGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPG--QGPPQ 2902
G Q G P P PG+P P Q G P G P PG QGPP
Sbjct: 226 GGNQPQGPP--------PPPGKPQGPPP------------QGGNKPQGPPPPGKPQGPP- 264
Query: 2903 RPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKG-PTLPTGL 2961
A G + + PP KP PP E NN P P G P P
Sbjct: 265 --------------AQGGSKSQSARS-PPGKPQGPPQQEGNNPQGPPPPAGGNPQQP--- 306
Query: 2962 ELVNRPPSSTELGRPNP 2978
PP+ G P P
Sbjct: 307 ---QAPPAGQPQGPPRP 320
Score = 50.4 bits (119), Expect = 5e-05
Identities = 68/243 (27%), Positives = 84/243 (34%), Gaps = 50/243 (20%)
Query: 4139 VSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPP--KP-GPVLQSGQGLPGVGIMPTVG 4195
VS + P + N GP +P GP PP KP GP Q G G P G
Sbjct: 23 VSQEESPSLIAGNPQGPSPQGGNKPQ----GPPPPPGKPQGPPPQGGNKPQGP---PPPG 75
Query: 4196 QLRAQL-QGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQ 4254
+ + QG +++P+ PQ Q Q PP Q P Q
Sbjct: 76 KPQGPPPQGDKSRSPRSPPGKPQGPPP-----------QGGNQPQGPPPPPGKPQGPPPQ 124
Query: 4255 GLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSP 4314
G G +PQ PG GP + P+ PP P P P G P PP P
Sbjct: 125 G--GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP------PPQGGNQPQGPPPPP 176
Query: 4315 QEPKRP----------------SQLPSPSSQLPTEAQLPPTHPGTPKPQGPTL----EPP 4354
+P+ P Q P P +Q PP P P PQG PP
Sbjct: 177 GKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPP 236
Query: 4355 PGR 4357
PG+
Sbjct: 237 PGK 239
Score = 45.4 bits (106), Expect = 0.002
Identities = 57/196 (29%), Positives = 71/196 (36%), Gaps = 48/196 (24%)
Query: 4235 QAVRQTPPYQEPGT-QTSPLQGLLGCQPQ-LGGFPGPQTGPLQELGAGP-------RPQG 4285
Q + P PG Q P QG G QPQ PG GP + G P +PQG
Sbjct: 144 QGDKSRSPRSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG 201
Query: 4286 PP-------RLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRP-------SQLPSPSSQLP 4331
PP +PPG P G P PP P +P+ P Q P P P
Sbjct: 202 PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----P 257
Query: 4332 TEAQLPPTHPGTP---------KPQGPTLE--------PPPGRVSPAAAQLADTLFSKGL 4374
+ Q PP G+ KPQGP + PPP +P Q +
Sbjct: 258 GKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA--GQPQ 315
Query: 4375 GPWDPPDNLAETQKPE 4390
GP PP ++ P+
Sbjct: 316 GPPRPPQGGRPSRPPQ 331
Score = 42.7 bits (99), Expect = 0.010
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 7/77 (9%)
Query: 4909 PPPEEPSPPP------SPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLA-SSPESARP 4961
PPP +P PP S A SP P P + P PP P +P + +P
Sbjct: 255 PPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP 314
Query: 4962 KPRARPPEEGEDSRPPR 4978
+ RPP+ G SRPP+
Sbjct: 315 QGPPRPPQGGRPSRPPQ 331
Score = 38.5 bits (88), Expect = 0.19
Identities = 28/85 (32%), Positives = 34/85 (40%), Gaps = 17/85 (20%)
Query: 4911 PEEPSPPPSPLAP--------SPASPPTEPLVELP---TEPLAEPPVP----SPLPLASS 4955
P+ P PP P P SP SPP +P P +P PP P P P +
Sbjct: 68 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 127
Query: 4956 PESARPKP--RARPPEEGEDSRPPR 4978
P P PP +G+ SR PR
Sbjct: 128 RPQGPPPPGKPQGPPPQGDKSRSPR 152
Score = 37.4 bits (85), Expect = 0.42
Identities = 40/155 (25%), Positives = 52/155 (33%), Gaps = 35/155 (22%)
Query: 4827 GTEPKKGEAEGP----GGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQE 4882
G P G+ +GP G K +G GP P KS+ K +
Sbjct: 49 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP----------PPQGDKSRSPRSPPGKPQ 98
Query: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942
P P+ Q Q PPP +P PP P PP P +P
Sbjct: 99 GPPPQGGNQP------------QGPPPPPGKPQGPPPQGGNRPQGPPP------PGKPQG 140
Query: 4943 EPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
PP + SP S KP+ PP+ G + P
Sbjct: 141 PPPQGDK---SRSPRSPPGKPQGPPPQGGNQPQGP 172
Score = 37.4 bits (85), Expect = 0.42
Identities = 71/242 (29%), Positives = 84/242 (34%), Gaps = 47/242 (19%)
Query: 3622 SQSPRLLTKLPGQLLPGHGLQP---------PQGPPGGQAGGLRLTPGGMALPGQPGGPF 3672
S+SPR P P G QP PQGPP GG R P G PG+P GP
Sbjct: 87 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--PQGGNR--PQGPPPPGKPQGPP 142
Query: 3673 LNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLAL---RSLGPDSRLLQERQLQLQQQRMQ 3729
++ + G P GG P + GP + ++ Q + Q
Sbjct: 143 PQGDKSRSPRSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200
Query: 3730 ----LAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGP------KPQGLMPP 3779
K + Q + Q G Q QGP + GP KPQG PP
Sbjct: 201 GPPPQGDKSRSSQSPPGKPQ---GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 257
Query: 3780 SSHQGLLVQQLS--------PQPPQGP--------QGMLGPAQVAVLQQQHPGALGPQGP 3823
QG Q S P PQGP QG PA Q Q P A PQGP
Sbjct: 258 GKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 317
Query: 3824 HR 3825
R
Sbjct: 318 PR 319
Score = 36.2 bits (82), Expect = 0.93
Identities = 25/79 (31%), Positives = 32/79 (40%), Gaps = 13/79 (16%)
Query: 4911 PEEPSPPPSPLAP--------SPASPPTEPLVELP---TEPLAEPPVPSPLPLASSPESA 4959
P+ P PP P P SP SPP +P P +P PP P P P+
Sbjct: 129 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQGG 187
Query: 4960 RPKPRARPPEEGEDSRPPR 4978
+ KP+ PP PP+
Sbjct: 188 K-KPQGPPPPGKPQGPPPQ 205
Score = 35.4 bits (80), Expect = 1.6
Identities = 21/69 (30%), Positives = 27/69 (39%), Gaps = 9/69 (13%)
Query: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968
PPP +P PP P PP P +P PP + SP KP+ PP
Sbjct: 174 PPPGKPQGPPPQGGKKPQGPPP------PGKPQGPPPQGDKSRSSQSPPG---KPQGPPP 224
Query: 4969 EEGEDSRPP 4977
+ G + P
Sbjct: 225 QGGNQPQGP 233
Score = 35.0 bits (79), Expect = 2.1
Identities = 19/67 (28%), Positives = 25/67 (37%), Gaps = 2/67 (2%)
Query: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970
P+ P PP P P P + P +P PP P P KP+ PP+
Sbjct: 190 PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG--KPQGPPPQG 247
Query: 4971 GEDSRPP 4977
G + P
Sbjct: 248 GNKPQGP 254
Score = 35.0 bits (79), Expect = 2.1
Identities = 36/125 (28%), Positives = 46/125 (36%), Gaps = 12/125 (9%)
Query: 359 RSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPG-----PLQ 413
+S + Q P + PP+ G+ P P QG P G P PG P Q
Sbjct: 208 KSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP-QGPPPQGGNKPQGPPPPGKPQGPPAQ 266
Query: 414 CEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEE--SPLSP--PPEESPTSPP--PEASRL 467
+K +PQ P PPP +P P PP P PP P+ R
Sbjct: 267 GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 326
Query: 468 SPPPE 472
S PP+
Sbjct: 327 SRPPQ 331
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 142 bits (359), Expect = 7e-33
Identities = 119/358 (33%), Positives = 155/358 (43%), Gaps = 46/358 (12%)
Query: 380 TPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMP 439
TP P + +G P+ P P + KP G ++ PQ+ P + P
Sbjct: 238 TPLSSPARSGPSARGTPRA-------PAHPS----QPKPKGLQALR-PPQVTPPRKDAAP 285
Query: 440 LLPPPEESPLSPPPEESPTSP--PPEASRLSPPPEELPA-------SPLPEALHLSRPLE 490
L P SPL+ P +P SP PP L PP P+ SP +A H P
Sbjct: 286 ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345
Query: 491 E-SPLSPPPEESP--LSPPPESSPFSPLEESPLSP-PEESPPSP------ALETPLSPPP 540
SPL+ PP ++P L+ PP +P SP PLSP SP +P L+ P SPPP
Sbjct: 346 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 405
Query: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF 600
+ P+ PF P SPP T P L+ PP + P SP P SPP S
Sbjct: 406 -SPPVQAPF-SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP-----PASPPMSPSATP 458
Query: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP---PEESPMSPPPEVSRLSPLP 657
PP PL+ PP + PP L+ PP + SPP P ++P SP + +SPL
Sbjct: 459 PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP-MSPLA 517
Query: 658 VVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP-EDSPTSPPPED---SPASPPP 711
+PP +PL P P SP +A R P P D+ S P +P PPP
Sbjct: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575
Score = 139 bits (349), Expect = 1e-31
Identities = 210/801 (26%), Positives = 273/801 (34%), Gaps = 130/801 (16%)
Query: 351 KAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPG 410
KA+ G R+ A + + + P P P P AL V G
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK---------- 56
Query: 411 PLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPP 470
PL A +G A + P P P +PP + + P R S
Sbjct: 57 PLAERAGGIGGATIPESAPRAGPTRTSRP--PASGRGERAPPAKNTSPGPVSSPGRASGT 114
Query: 471 PEELPASPLPEALHLSRPLEESPLSPPPEESPLS---------PPPESSPFSPLEESPLS 521
P + + + P+ S LS P P + + S +
Sbjct: 115 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 174
Query: 522 PPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASR-------LSP 574
E P PA PP E S +S E T P P A R L
Sbjct: 175 GTEVGLPRPAPSARPRPPTEGPRKS-------VSSASEHSTTEPSPAARRRPSAGGGLQR 227
Query: 575 PPEES-PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPED- 632
P S S P SP P A R P P P P+ PP+ ++PP +D
Sbjct: 228 PASRSLSSSATPLSSPARSGPSA-RGTPRAPAHPSQPKPKGLQALRPPQ---VTPPRKDA 283
Query: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT---SPPPEA--S 687
+P P SP++ P + SP S + P SP + PP ++ T SP +A S
Sbjct: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLP---SPPATPPSQATTSLGSPTLQATHS 340
Query: 688 RLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL---- 743
L PP +PPP+ PA P P PL PL P + HL
Sbjct: 341 FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400
Query: 744 -SPRPEEPHLSP--RPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQ 800
SP P P +P P P +SP A P +P P L A P + SP A P
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAP----PSLAAPPLQVPPSPPASPP----- 451
Query: 801 PEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPL 860
+SP P +P P L+ P + P P L+ P L
Sbjct: 452 -----MSPSATPPPQAPPP----LAAPPLQLAKPPPQAPPALATPP-------------L 489
Query: 861 SPRPEKPPEEPGQCP--APEELPLFP---PPGEPSLSPLLGEPALSEPGEPPLSPL---- 911
P P PGQ P LP+ P PP P P+L P L P PP SP
Sbjct: 490 QALPSPPASFPGQAPFSPSASLPMSPLATPP--PQAPPVLAAPLLQVPPSPPASPTLQAP 547
Query: 912 ---PEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP-ALSPLGELEYPFGAKG-D 966
P P + P L+ L P P PP SP T + P A P +G D
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 607
Query: 967 SDPESPLAAPILETPISPPPEANCT-------DPEPVPPMILPPSPGSPVGPASPILMEP 1019
S PE AA SPPP+A P PP+ +PG+P+ P
Sbjct: 608 SGPEGGAAA-------SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL---------P 651
Query: 1020 LPPQCSPLLQHSL--VPQNSPPSQCSP-PALPLSVPSPLSPIGK-VVGVSDEAELHEMET 1075
PP P L + + P +P P PSP + GK G A +
Sbjct: 652 WPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 711
Query: 1076 EKVSEPECPALEPSATSPLPS 1096
++ E AL+ S L S
Sbjct: 712 ARLGELPLGALQASVVQHLLS 732
Score = 131 bits (329), Expect = 2e-29
Identities = 194/724 (26%), Positives = 242/724 (33%), Gaps = 144/724 (19%)
Query: 529 SPALETP--LSPPPEASPLSPPFEESPLSPP----------------------------P 558
+PA P L+P P SP PP P++P P
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPP----PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 559 EELPTSPPPEASRLSPPP----EESPMSPPPEESPMSPPPEASRLFPP--FEESPLSPPP 612
E P + P SR PP E +P + P+S P AS P + L
Sbjct: 72 ESAPRAGPTRTSR--PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129
Query: 613 EES----PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668
EE+ + P+ S LS P +P +P P ++R S P P
Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGP----TPGTPSPAMARRSRAAGTEVGLPRPAP 185
Query: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL 728
S PP E P AS E S T P SPA+ + L S L
Sbjct: 186 SARPRPPTEGPRKSVSSAS------EHSTTEP----SPAARRRPSAGGGLQRPASRSLSS 235
Query: 729 PEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL 788
P P GP P P +P+ L QA P PQ P A P L
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGL--QALRP---PQVTPPRKDAAPA---L 287
Query: 789 SPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE 848
P + P +P P SP P L +P P P + L SP +
Sbjct: 288 GPLSSSPLATPSPSAPP-SPSAP-PSLQTLPSPPATPPSQATTSLG--------SPTLQA 337
Query: 849 SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPL----------LGEP 898
+H L PPLSP PP+ P P PP P LSPL L
Sbjct: 338 THSF--LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 395
Query: 899 ALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELE 958
L P PP SP P + P SP P +SP PP PP L AAPP
Sbjct: 396 LLQAPFSPPPSP-PVQAPFSPPASPPVSPSATPPSQAPPSL------AAPPL-------- 440
Query: 959 YPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILME 1018
P SP A+P + +PPP+A PP+ PP + P +P +
Sbjct: 441 --------QVPPSPPASPPMSPSATPPPQAP-------PPLAAPPLQLAKPPPQAPPALA 485
Query: 1019 PLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKV 1078
P Q P S Q S P PL+ P P +P V+ A L ++
Sbjct: 486 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP--PVLA----APLLQVPP--- 536
Query: 1079 SEPECPALEPSATSPLPSPMGDLSCP------APSPAPALDDFSGLGEDTAPLDGIDAPG 1132
S P P L+ P P P +S P AP P P ++ L G D G
Sbjct: 537 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS-----RSPSSTLSGPDLAG 591
Query: 1133 SQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPV 1192
TP EL+G + A P C A P AP
Sbjct: 592 HSSSATSTP----EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 647
Query: 1193 APTP 1196
AP P
Sbjct: 648 APLP 651
Score = 113 bits (283), Expect = 5e-24
Identities = 219/848 (25%), Positives = 295/848 (34%), Gaps = 125/848 (14%)
Query: 1910 GTPGLEGSRTPLQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGG-FFSPEPGE 1968
G G G + +R GG+ +P S+P + P ER + PG
Sbjct: 48 GAAGAVGRKPLAERA---GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGP 104
Query: 1969 PDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINF 2028
SP SG T P P + GL + K E + S +S + +
Sbjct: 105 VSSPGRASGTTRPG----PLGQ---KGLRISAEETVARGKATEAPKRSALSAGARRDTSG 157
Query: 2029 PNLKQDYPDWSSRCKQI---MKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQIN 2085
P P + R + + L R P+A P + + + ++ + + + +
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217
Query: 2086 KQTKVGDIARKTDRP----ALHLRIPPQ--PGALGSPPPAAAPTIFIGSPTTPAGLSTSA 2139
+ + G + R R A L P + P A G+P A P S P GL
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP-----SQPKPKGLQA-- 270
Query: 2140 DGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVP-SQDPFGLAPAYPLEPRFPTAPPTYPP 2198
L+PP + P D+ PA P S P LA P P P+APP+
Sbjct: 271 ---LRPPQVTPPRKDA-----------APALGPLSSSP--LATPSPSAPPSPSAPPSLQT 314
Query: 2199 YPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVP 2258
PSP PA PP +S G+ H+ P P +TP P P +L L P
Sbjct: 315 LPSP---PATPPSQATTSL-GSPTLQATHSFLPSPPLSPLATPPPQAPPAL-ALPPLQAP 369
Query: 2259 ESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGG 2318
SP PL +P P + A+ + + SP PP P+S
Sbjct: 370 PSPPAS--PPLSPLATPSPQAPNALAVHLLQAPF---SPPPSPPVQAPFSPPAS------ 418
Query: 2319 LELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPY 2378
P++P A+ P L P + PP+ SPP P P P
Sbjct: 419 ----------PPVSPSATPPSQAPPSLAAPPLQVPPSPPA--SPPMSPSATPPPQAPPPL 466
Query: 2379 AQPPL---TPRPQPP-----PPESCCALPPRSLPSD-PFSRVPASPQSQSSSQSPLTPRP 2429
A PPL P PQ P PP PP S P PFS + P S ++ P P
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526
Query: 2430 LSAEAF--CPS-PVTPRFQSPDPYSRPP--------SRPQSRDPFAPLHKPPRPQPPEVA 2478
L+A PS P +P Q+P RPP S P+ AP PP + P
Sbjct: 527 LAAPLLQVPPSPPASPTLQAP---RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 583
Query: 2479 FKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTF 2538
LA S A P L +G S P + + A+ P+P F
Sbjct: 584 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP-PLAF 642
Query: 2539 PQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSS 2598
A G P PP PG G+ + + T G P+S T A G P SP G S
Sbjct: 643 RGAPGAPLPWPPATGPG--SADGLCTIY---ETEG-PESA--TPAPGALDPGPSP-GTSG 693
Query: 2599 GSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGI------TSPVEKREDPGTGM 2652
G G S P A G LP GA Q S + T + E G
Sbjct: 694 GKAAAGAGAG---ASSRSPKQARLGELPL---GALQASVVQHLLSRTLLLAAAEGAAGGS 747
Query: 2653 GSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAG 2712
G AE G + LS EL R ELL R ++ T+ +
Sbjct: 748 GGGPGGAEGGGVTGGARAALSDAEL------GRWAELLSPLDESRASI--TSVTSFSPDD 799
Query: 2713 AVGPPGSW 2720
P G W
Sbjct: 800 VASPQGDW 807
Score = 99.0 bits (245), Expect = 1e-19
Identities = 196/780 (25%), Positives = 263/780 (33%), Gaps = 151/780 (19%)
Query: 2087 QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFI-------------------- 2126
+ K G AR A L P PG+ PPP + +
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 2127 ----------GSPTTPAGLSTSADGFLKPPA-GSVPGP-DSPGELFLKLPP----QVPAQ 2170
PT + S G PPA + PGP SPG P Q +
Sbjct: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 126
Query: 2171 VPSQDPF--GLAPAYPLE------PRFPTAPPTYPPYPSP--------TGAPAQPPMLGA 2214
+ +++ G A P R T+ PT P PSP G P
Sbjct: 127 ISAEETVARGKATEAPKRSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVGLPRPAP 185
Query: 2215 SSRP---------GAGQPGEFHTTPPG-TPRHQPSTPDPFLKPRCPSLDNLAVP-ESPGV 2263
S+RP E TT P R +PS +P SL + A P SP
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245
Query: 2264 GGGKA----------SEP------LLSPPPFGESRKAL-----EVKKEELGASSPS---- 2298
G A S+P L PP RK + L SPS
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305
Query: 2299 -YGPPNLGFVDSP------SSGTHLGGLELKTPDVF--KAPLTPRASQVEPQSPGLGLRP 2349
PP+L + SP + T LG L+ F PL+P A+ P L L P
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 2350 QEPPPAQALAP--SPPSHPDIFRPGSYTDPYAQPPLTPRPQPP--PPESCCALPPRSLPS 2405
+ PP+ +P SP + P P + Q P +P P PP P S A PP S +
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 425
Query: 2406 DPFSRVP---ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDP 2462
P S+ P A+P Q P +P P+S A TP Q+P P + PP + P
Sbjct: 426 TPPSQAPPSLAAPPLQVPPSPPASP-PMSPSA------TPPPQAPPPLAAPPLQLAKPPP 478
Query: 2463 FAP----------LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALP--AGPAGELHAKV 2510
AP L PP P + F + S A P A P A P ++
Sbjct: 479 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538
Query: 2511 PSG---QPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPP----HGIN 2563
P+ Q P +PG V P R T A G P P L P H +
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSGP---RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595
Query: 2564 SHFGP--------GPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSV 2615
+ P GP G S HP+ GP+ +PL P
Sbjct: 596 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 655
Query: 2616 LPPPAPDGSLP-YLSHGASQRSGITSPVEKREDPGTGMGSSLATAEL-PGTQDPGMSGLS 2673
P + DG Y + G + ++ PGT G + A A ++ P + L
Sbjct: 656 TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 715
Query: 2674 QTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLS 2733
+ L L+ +++ + R L E AA +G GP G+ G + A LS
Sbjct: 716 ELPL------GALQASVVQHLLSRTLLLAAAEGAAGGSGG-GPGGAEGGGVTGGARAALS 768
Score = 69.7 bits (169), Expect = 8e-11
Identities = 131/540 (24%), Positives = 173/540 (32%), Gaps = 94/540 (17%)
Query: 2449 PYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG--EL 2506
P +R P R P +P +PP P P G+ G P A AG G +
Sbjct: 17 PAARAPGLLTPRPPGSP--RPPPPVTPAALRVLGAAG----AVGRKPLAERAGGIGGATI 70
Query: 2507 HAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHF 2566
P P R P +G P P + T P V P +PG
Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAP-PAKNTSPGPVSSPGRASGTTRPG----------- 118
Query: 2567 GPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLP 2626
P G S TVA G + S+G+ ++ G +P P ++
Sbjct: 119 -PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP---------GTPSPAMA 168
Query: 2627 YLSHGASQRSGITSPVE--KREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQ 2684
S A G+ P + P G S+++A T +P + + QR
Sbjct: 169 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228
Query: 2685 RLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQD 2744
R L L + +A G P A PS P + L + P
Sbjct: 229 ASRSL----SSSATPLSSPARSGPSARGTPRAP----AHPSQPKPKGLQALRPPQV---- 276
Query: 2745 KSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPY 2804
PP K + P LGP S L+ P P A PS S Q + P
Sbjct: 277 ------TPPRKDAAPALGP---LSSSPLATPSPSAPPSPSAPPSLQTL----------PS 317
Query: 2805 PGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGP 2864
P + P Q L + A P P L A P A + LP
Sbjct: 318 PPATPPSQATTSLGSP-----------TLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366
Query: 2865 GEPVPGPAGP-----------AQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSED- 2912
P PA P A H +Q P +P P Q P P PVS
Sbjct: 367 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPSA 425
Query: 2913 -PHRLAPEGLRGLAVSGLPPQKPSAPPA-PELNNSLHPTPHTKGPTLPTGLELVNRPPSS 2970
P AP L + P Q P +PPA P ++ S P P P L+L PP +
Sbjct: 426 TPPSQAPPSL-----AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480
Score = 69.7 bits (169), Expect = 8e-11
Identities = 153/656 (23%), Positives = 217/656 (33%), Gaps = 121/656 (18%)
Query: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPP 2392
PRA P R + PPA+ +P P S P + P Q L +
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134
Query: 2393 ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSR 2452
P+ S + A + +S +P TP P A + P P +R
Sbjct: 135 RGKATEAPKR------SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 188
Query: 2453 PPSRPQSRDP-----FAPLHKPPRPQP-----PEVAFKAGSLAHTSLGAGGFPAALPA-- 2500
P RP + P A H P P P A SL + P + PA
Sbjct: 189 P--RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246
Query: 2501 GPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQP-GLPPP 2559
GP+ + P+ P+ + G A P + T P+ P+L P P P P
Sbjct: 247 GPSARGTPRAPAH--PSQPKPKGLQAL----RPPQVTPPRKDAAPALGPLSSSPLATPSP 300
Query: 2560 HGINSHFGPGP--TLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP 2617
S P TL P +T + AT + GSP ++ S S LSPL P P
Sbjct: 301 SAPPSPSAPPSLQTLPSPPATPPSQATTSL---GSPTLQATHSFLPSPPLSPLATP---P 354
Query: 2618 PPAPDG-SLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTE 2676
P AP +LP L S + + P+ P ++LA L P S Q
Sbjct: 355 PQAPPALALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-- 410
Query: 2677 LEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQ 2736
A + PP S A P S A L+
Sbjct: 411 -------------------------------APFSPPASPPVSPSATPPSQAPPSLA--- 436
Query: 2737 TPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDD----------RLSRPPPPATPSSMDV 2786
+ + +PPS + P + P + P +L++PPP A P+
Sbjct: 437 ---------APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487
Query: 2787 NSRQLVGGSQAFYQRAPY--PGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPE 2844
+ L +F +AP+ SLP+ Q AA ++ S P++P +
Sbjct: 488 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP--PASPTLQ 545
Query: 2845 LGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRP 2904
R+ PGP V GP + L PG P P + P
Sbjct: 546 APRR----------PPTPGPDTSVSGP-----------RLTLALAPGPPPPPSRSPSSTL 584
Query: 2905 RFYPVS--EDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLP 2958
++ PE LRG S PP EL + HP ++GP P
Sbjct: 585 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL-AACHPAAWSRGPAPP 639
Score = 67.0 bits (162), Expect = 5e-10
Identities = 109/392 (27%), Positives = 139/392 (35%), Gaps = 74/392 (18%)
Query: 4023 GKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQP 4082
G Q ++SS AT S + GP A GT P + A PS
Sbjct: 223 GGLQRPASRSLSSSATPLSSPARSGPSARGT-PRAPA------HPS-------------- 261
Query: 4083 QPQPSSLQ-LQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSS---EASSVPHLLAQPS 4138
QP+P LQ L+PP P ++ +L G S L + S S S+ P L PS
Sbjct: 262 QPKPKGLQALRPPQVTPPRKDAAPAL----GPLSSSPLATPSPSAPPSPSAPPSLQTLPS 317
Query: 4139 VSLGDQPGSMTQNLLGPQ----QPMLERPMQNNTGPQPPKPGPVLQSG--QGLPGVGIMP 4192
P T +L P L P + PP+ P L Q P P
Sbjct: 318 PP-ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP 376
Query: 4193 TVGQLRA---QLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQ 4249
+ L Q LA + SP +QA + TPP Q P +
Sbjct: 377 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSL 435
Query: 4250 TSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGP----- 4304
+P L P P P A P PQ PP L APP L+ P P
Sbjct: 436 AAP---------PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486
Query: 4305 ----VHPTPPPSSP-QEPKRPS-QLP-SPSSQLPTEA---------QLPPTHPGTPKPQG 4348
P+PP S P Q P PS LP SP + P +A Q+PP+ P +P Q
Sbjct: 487 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546
Query: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380
P P PG ++ + L P PP
Sbjct: 547 PRRPPTPG----PDTSVSGPRLTLALAPGPPP 574
Score = 66.6 bits (161), Expect = 6e-10
Identities = 150/672 (22%), Positives = 221/672 (32%), Gaps = 135/672 (20%)
Query: 4325 SPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA 4384
+P+++ P L P PG+P+P PPP V+PAA ++ + G P LA
Sbjct: 16 TPAARAP--GLLTPRPPGSPRP------PPP--VTPAALRVLGAAGAVGRKP------LA 59
Query: 4385 ETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGE--PIGA 4442
E + G +PE++ + P + + N P+ +
Sbjct: 60 E------------RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS 107
Query: 4443 PGTSNHLLLAGPRSEAGHLLL--QKLLRAKNVQLSTGRG-SEGLRAEINGHID------- 4492
PG ++ GP + G + + + R K + S G R + +G
Sbjct: 108 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 167
Query: 4493 ---SKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLV---SSRKKLRKEDGVR 4546
S+ AG E G P A R P K V AS+ S + R G
Sbjct: 168 ARRSRAAGTE---VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 224
Query: 4547 ASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDY 4606
+ L S PL+ PA + + P P Q + +G P
Sbjct: 225 LQRPASRSLSS--SATPLSSPARSGPSARGTPRAPAHP--SQPKPKGLQALRPPQVTPPR 280
Query: 4607 YSQLLTKNNLSNPP--TPPSSLPPTP--PPSVQQKMVNGVTPSEELGEHPKDAASARDSE 4662
LS+ P TP S PP+P PPS+Q TP P A ++ S
Sbjct: 281 KDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATP-------PSQATTSLGSP 333
Query: 4663 RALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRF 4722
L+ T L+ L TPP + + + SP PAS P S L +P+
Sbjct: 334 -TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP----PASPPLSPLATPSPQA 388
Query: 4723 PHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEV 4782
P+ + Q + P P+ S P P P + P L +
Sbjct: 389 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 448
Query: 4783 SVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKE 4842
S ++ SA + A L K P P++P T P + P
Sbjct: 449 SPPMSPSATPPPQAPPPL-AAPPLQLAKPP-------PQAPPALATPPLQALPSPP---- 496
Query: 4843 KGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLD 4902
A PG AP P+ ++L
Sbjct: 497 -------------------ASFPG-----------------QAPFSPS--------ASLP 512
Query: 4903 VRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPE----- 4957
+ L+ PPP+ P +PL P SPP P ++ P PP P P S P
Sbjct: 513 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP----RRPPTPGPDTSVSGPRLTLAL 568
Query: 4958 -SARPKPRARPP 4968
P P +R P
Sbjct: 569 APGPPPPPSRSP 580
Score = 61.6 bits (148), Expect = 2e-08
Identities = 139/564 (24%), Positives = 189/564 (33%), Gaps = 120/564 (21%)
Query: 4012 PGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSG 4071
PG LG L E+ +ATE P L+ G ++ PG P+++
Sbjct: 117 PGPLGQKGLRISAEETVA----RGKATEAPKR---SALSAGARRDTSGPTPGTPSPAMAR 169
Query: 4072 DSQLLLVQPQ-PQPQPSSLQLQPPLRLPGQQQQQVSLLHT------------AGGGSHGQ 4118
S+ + P+P PS+ + +PP P + S T AGGG
Sbjct: 170 RSRAAGTEVGLPRPAPSA-RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228
Query: 4119 LGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPV 4178
SS A+ L+ P+ S G+ P P +P + +PP+ P
Sbjct: 229 ASRSLSSSATP----LSSPARSGPSARGTPR----APAHPSQPKP-KGLQALRPPQVTP- 278
Query: 4179 LQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVR 4238
P P +G L + LA SP LQ L
Sbjct: 279 -------PRKDAAPALGPLSSS---PLATPSPSAPPSPSAPPSLQTL------------- 315
Query: 4239 QTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRL--------P 4290
+PP P T+ L G Q P P PL A P PQ PP L P
Sbjct: 316 PSPPATPPSQATTSL-GSPTLQATHSFLPSPPLSPL----ATPPPQAPPALALPPLQAPP 370
Query: 4291 APPGALSTGPVLGP---------VHP-----TPPPSSPQE-----PKRPSQLPS--PSSQ 4329
+PP + P+ P VH +PPPS P + P P PS P SQ
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430
Query: 4330 LPTE-----AQLPPTHPGTPKPQGPTLEPPPGRVSPAAA----------QLADTLFSKGL 4374
P Q+PP+ P +P P P+ PPP P AA Q L + L
Sbjct: 431 APPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 489
Query: 4375 GPWDPPDNLAETQKP-EQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKR 4433
P Q P S+ +P P + Q P P + Q+ +R
Sbjct: 490 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 549
Query: 4434 EANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDS 4493
P P TS ++GPR L L S S ++ GH S
Sbjct: 550 ----PPTPGPDTS----VSGPR------LTLALAPGPPPPPSRSPSSTLSGPDLAGH-SS 594
Query: 4494 KLAGLEQKLQGTPSNKEDAAARKP 4517
++L+G S E AA P
Sbjct: 595 SATSTPEELRGYDSGPEGGAAASP 618
Score = 54.3 bits (129), Expect = 3e-06
Identities = 73/311 (23%), Positives = 111/311 (35%), Gaps = 37/311 (11%)
Query: 4115 SHGQLGSGSSSEASSVPHLLAQPSVSLGDQP----GSMTQNLLGPQQPMLERPMQNNT-G 4169
S G + S + ++ P L Q + + + G T+ P++ L + +T G
Sbjct: 101 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE---APKRSALSAGARRDTSG 157
Query: 4170 PQPPKPGPVLQSGQGLPG--VGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLM 4227
P P P P + G VG+ R + + P+ S + +
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP---TEGPRKSVSSASEHSTTEPSPA 214
Query: 4228 QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQG-- 4285
R+ + Q P + + +PL P G P P Q P+P+G
Sbjct: 215 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-----PKPKGLQ 269
Query: 4286 --------PPRLPAPP--GALSTGPVL-----GPVHPTPPPSSPQEPKRPSQLPSPSSQL 4330
PPR A P G LS+ P+ P P+ PPS P P+ PS ++
Sbjct: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329
Query: 4331 PTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE 4390
L TH P P L PP + PA A L + P PP + T P+
Sbjct: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALA--LPPLQAPPSPPASPPLSPLATPSPQ 387
Query: 4391 QSSLVPGHLDQ 4401
+ + HL Q
Sbjct: 388 APNALAVHLLQ 398
Score = 53.9 bits (128), Expect = 4e-06
Identities = 109/429 (25%), Positives = 144/429 (33%), Gaps = 74/429 (17%)
Query: 3999 PGMPAKP--LQHFSSPGALGPTLLLTGKEQNTVD--------PAVSSEATEGPSTHQGGP 4048
P P+ P LQ SP A P+ T T+ P +S AT P
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA----- 357
Query: 4049 LAIGTTPESMATEPGEVKPSLSGDSQLL-LVQPQPQPQPSSLQ---LQPPLRLPGQQQQQ 4104
P ++A P + PS L L P PQ P++L LQ P P Q
Sbjct: 358 ------PPALALPPLQAPPSPPASPPLSPLATPSPQA-PNALAVHLLQAPFSPPPSPPVQ 410
Query: 4105 VSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPM 4164
A S S++ S P LA P + + P + P P P
Sbjct: 411 APFSPPASPPV-----SPSATPPSQAPPSLAAPPLQVPPSPPASP-----PMSPSATPPP 460
Query: 4165 QNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQA 4224
Q PP P LQ + P L+A L A P SP +
Sbjct: 461 Q----APPPLAAPPLQLAKPPPQAPPALATPPLQA-LPSPPASFPGQAPFSPSASLPMSP 515
Query: 4225 LLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF--------PGPQT---GP 4273
L TPP Q P +PL + P PGP T GP
Sbjct: 516 LA-------------TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 562
Query: 4274 LQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS--PSSQLP 4331
L P P PP P + +GP L H + S+P+E + P ++ P
Sbjct: 563 RLTLALAPGPPPPPS--RSPSSTLSGPDLAG-HSSSATSTPEELRGYDSGPEGGAAASPP 619
Query: 4332 TEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQ 4391
+A+L HP +GP PP A + G G D + ET+ PE
Sbjct: 620 PDAELAACHPAAWS-RGPA---PPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 675
Query: 4392 SSLVPGHLD 4400
++ PG LD
Sbjct: 676 ATPAPGALD 684
Score = 53.9 bits (128), Expect = 4e-06
Identities = 31/85 (36%), Positives = 38/85 (44%), Gaps = 16/85 (18%)
Query: 4906 LSAPPPEEP------------SPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLA 4953
L+ P P+ P SPPPSP +P SPP P P P A PP +P LA
Sbjct: 381 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP----PVSPSATPPSQAPPSLA 436
Query: 4954 SSPESARPKPRARPPEEGEDSRPPR 4978
+ P P P A PP + PP+
Sbjct: 437 APPLQVPPSPPASPPMSPSATPPPQ 461
Score = 47.0 bits (110), Expect = 5e-04
Identities = 168/743 (22%), Positives = 227/743 (30%), Gaps = 139/743 (18%)
Query: 4281 PRPQGPPRLPAP--PGALSTGPVLGPVHPTP-------------PPSSPQE-PKRPSQLP 4324
PRP G PR P P P AL G V P P S+P+ P R S+ P
Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPP 86
Query: 4325 SPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA 4384
+ + PP +P P PGR S L KGL + +A
Sbjct: 87 ASGRG----ERAPPAKNTSPGPVSS-----PGRASGTTRP--GPLGQKGLRI-SAEETVA 134
Query: 4385 E---TQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIG 4441
T+ P++S+L G +G P ++ + R A G + G P
Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPT-PGTPSPAMARRSR----AAGTEV------GLPRP 183
Query: 4442 APGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQK 4501
AP GPR GL+ + + S L
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 4502 LQGTPSNK-EDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELS 4560
+ PS + A P PKPK +Q V+ +K A+ AL LS
Sbjct: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK-------DAAPAL-----GPLS 291
Query: 4561 LLPLTEPAITANFSLFAPFG----SGCPVNGQSQLRGAFGS---------------GALP 4601
PL P+ +A S AP P SQ + GS L
Sbjct: 292 SSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 351
Query: 4602 TGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDS 4661
T P L L PP+PP+S P +P + + N L H A +
Sbjct: 352 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA------LAVHLLQAPFSPPP 405
Query: 4662 ERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPR 4721
++ + ++ TPP + + SP PAS P S P+
Sbjct: 406 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP----PASPPMSPSATPPPQ 461
Query: 4722 FPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGAL---GLEVPGKLPVTTWEKGK 4778
P A P+ P P T P AL PG+ P +
Sbjct: 462 AP---------PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP----- 507
Query: 4779 GSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGT--EPKKGEAE 4836
S L +S A V A LL + P SP + T P++
Sbjct: 508 ----SASLPMSPLATPPPQAPPVLAAPLLQV----------PPSPPASPTLQAPRRPPTP 553
Query: 4837 GPGGKEKGLE---GKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHS 4893
GP G +P P + + L G L S P
Sbjct: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH--------SSSATSTPEELRG 605
Query: 4894 YTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSP---- 4949
Y S + ++PPP+ P A S P P PL PP P
Sbjct: 606 YD---SGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 662
Query: 4950 ----LPLASSPESARPKPRARPP 4968
+ PESA P P A P
Sbjct: 663 GLCTIYETEGPESATPAPGALDP 685
Score = 39.7 bits (91), Expect = 0.084
Identities = 105/458 (22%), Positives = 139/458 (30%), Gaps = 117/458 (25%)
Query: 2543 GEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTG 2602
G + P PGL P S P P P + A G PL +G G
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVT--PAALRVLGAAGAV--GRKPLAERAGGIG 66
Query: 2603 ESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELP 2662
+ +P AP S + G +P K PG A+
Sbjct: 67 GA----------TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRAS---- 112
Query: 2663 GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGA 2722
GT PG G Q+ + + + R + + +A +AGA
Sbjct: 113 GTTRPGPLG------------QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP 160
Query: 2723 EPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPS 2782
SPA + SR AGT+ VGLP RP P A P
Sbjct: 161 GTPSPAMARRSRA----AGTE-----VGLP---------------------RPAPSARPR 190
Query: 2783 SMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPG 2842
R+ V + P P + +++ +A ++ S S+
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAA------------RRRPSAGGGLQRPASRSLSSSAT 238
Query: 2843 PELGRQALGSPLAGISTRLPG-PGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPP 2901
P L A P A + R P P +P P KGL PP
Sbjct: 239 P-LSSPARSGPSARGTPRAPAHPSQPKP----------------KGL-------QALRPP 274
Query: 2902 QRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTK-------- 2953
Q P + A L L+ S L PSAPP+P SL P
Sbjct: 275 Q-------VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327
Query: 2954 ----GPTLPTGLELVNRPPSSTELGRPNPLALEAGKLP 2987
PTL + PP S L P P A A LP
Sbjct: 328 TSLGSPTLQATHSFLPSPPLS-PLATPPPQAPPALALP 364
Score = 37.7 bits (86), Expect = 0.32
Identities = 73/298 (24%), Positives = 96/298 (32%), Gaps = 51/298 (17%)
Query: 4031 PAVSSEAT---EGPSTHQGGPLAIGTTPESM------ATEPGEVKPSLSGDSQLLLVQPQ 4081
P VS AT + P + PL + +P + AT P + P L+ L L +P
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP-LQLAKPP 477
Query: 4082 PQPQPS----SLQL--QPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA 4135
PQ P+ LQ PP PGQ S S ++ P +LA
Sbjct: 478 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM---------SPLATPPPQAPPVLA 528
Query: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVG 4195
P + + P P P L+ P + PP PGP + + P
Sbjct: 529 APLLQVPPSP---------PASPTLQAPRR------PPTPGPDTSVSGPRLTLALAPGPP 573
Query: 4196 QLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQG 4255
++ P L S + L + A PP E P
Sbjct: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA-CHPAAW 632
Query: 4256 LLGCQPQLG--GFPG------PQTGPLQELGAGP--RPQGPPRLPAPPGALSTGPVLG 4303
G P L G PG P TGP G +GP PGAL GP G
Sbjct: 633 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 690
Score = 35.8 bits (81), Expect = 1.2
Identities = 62/274 (22%), Positives = 88/274 (32%), Gaps = 50/274 (18%)
Query: 4711 PESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLP 4770
P S GE AP + G RA P P G GL + +
Sbjct: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRP-------------GPLGQKGLRISAEET 132
Query: 4771 VTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEP 4830
V +GK +E +SA A ++ +G P P
Sbjct: 133 VA---RGKATEAPKRSALSAGARRDTSG------------------------PTPGTPSP 165
Query: 4831 KKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPT 4890
G E GL +P P + + S + P+
Sbjct: 166 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 225
Query: 4891 QHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPP----V 4946
Q + ++S+ LS+P PS +P AP+ S P ++ P PP
Sbjct: 226 QRPASRSLSS-SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 284
Query: 4947 PSPLPLASSPESARPKPRARPPEEGEDSRPPRLK 4980
P+ PL+SSP A P P A P S PP L+
Sbjct: 285 PALGPLSSSP-LATPSPSAPP----SPSAPPSLQ 313
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 142 bits (358), Expect = 9e-33
Identities = 188/614 (30%), Positives = 231/614 (37%), Gaps = 121/614 (19%)
Query: 3684 QHSGGAGSLAGPSGG--FFPGNLALRSLGPDSRLLQERQLQLQQ-----------QRMQL 3730
Q G+ L PS G F N AL + P + Q Q Q Q Q +
Sbjct: 374 QGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQS-QAQPQTGSGASRALPSWQEVSH 432
Query: 3731 AQKLQQ----QQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP-----QGLMPPSS 3781
AQ+L+Q +QQ + QQH QQQ Q + GP P + + PS
Sbjct: 433 AQQLKQIAANRQQHARMQQH-------QQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSF 485
Query: 3782 HQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLA 3841
Q Q SP P G G G ++V G QG H VLM Q S
Sbjct: 486 GQQTFSPQSSPMP--GVAGGSGQSKVMANYMYKAGP-SAQGGHLDVLMQQKPQDLSRSFI 542
Query: 3842 QQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQ 3901
M R QG+ L H + L +Q SL
Sbjct: 543 NNPHPAMEPR---------------QGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYT 587
Query: 3902 QQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQ----LQQQQQQLQQ 3957
QQQQ QQQQQ QQQQQQQ QQQQQ QQQQ QQQQ QQQQQQQ QQQQQQ QQ
Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647
Query: 3958 QQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQ--------------QQQQQQVALGPGMPA 4003
QQQQQQQQ QQQQQQQQ +++L S QQ Q Q G G
Sbjct: 648 QQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQV 707
Query: 4004 KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLA-IGTTPESMATEP 4062
Q +G QNT P+ S P+T G + + + +
Sbjct: 708 SQQQRQDQHSVVG---------QNT-GPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKK 757
Query: 4063 GEVKPSLSGDSQLLLVQPQ---------PQPQPSSLQLQPPLRLPGQQQQQVSLLHTA-- 4111
++ + Q LL+Q Q PQ Q + +PP Q++ ++ TA
Sbjct: 758 QTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQY 817
Query: 4112 -GGGSHGQLGSGS--------------SSEASSVPHLLAQPSVSLGDQPGSMTQNL---- 4152
GG S L S +S S H PS+S Q M NL
Sbjct: 818 SGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQ 877
Query: 4153 -------LGPQQPMLER-PMQ------NNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLR 4198
G Q +R P Q N P+PP GP + G G + QLR
Sbjct: 878 PNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLR 937
Query: 4199 AQLQGVLAKNPQLR 4212
L +A P R
Sbjct: 938 PNLTHSMASMPPQR 951
Score = 95.5 bits (236), Expect = 1e-18
Identities = 114/420 (27%), Positives = 162/420 (38%), Gaps = 57/420 (13%)
Query: 3570 QQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLT 3629
Q+ +QL Q+ +++H + QQ QQQ Q + + PS P
Sbjct: 428 QEVSHAQQLKQIAANRQQHARM---------QQHQQQHQPTNWSALPSSAGPSPGPFGQE 478
Query: 3630 KLPGQLLPGHGLQPPQGPPGGQAGG---LRLTPGGM--ALPGQPGGPFLNTALAQQQQQQ 3684
K+P P P G AGG ++ M A P GG L QQ+ Q
Sbjct: 479 KIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHL--DVLMQQKPQD 536
Query: 3685 HSGGAGSLAGPS-----GGFFP--------GNLALRSLGPDSR---LLQERQLQLQQQRM 3728
S + P+ G P N + S+ P LL Q Q QQQ+
Sbjct: 537 LSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQ 596
Query: 3729 QLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQ 3788
Q Q+ QQQQQQQQQQQ QQQQQQ + Q + Q
Sbjct: 597 QQQQQQQQQQQQQQQQQQ-------QQQQQQQSSISAQQ----------QQQQQSSISAQ 639
Query: 3789 QLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGL- 3847
Q Q Q Q Q QQQ P + Q Q L+ L L QQ Q
Sbjct: 640 QQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQP 699
Query: 3848 ---MGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMS-HSGQPKLSAQPMGSLQQLQQQ 3903
MG+++ QQQ+Q QH G G S + ++G +++Q QQL +
Sbjct: 700 IAGMGYQV---SQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGK 756
Query: 3904 QQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQ 3963
+Q Q+Q ++Q+QQ LQQQ +++ Q Q + + + Q++ + Q Q
Sbjct: 757 KQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQ 816
Score = 70.9 bits (172), Expect = 3e-11
Identities = 135/560 (24%), Positives = 205/560 (36%), Gaps = 92/560 (16%)
Query: 3226 PAASGDELDKMESSLVASELPLLIEDLLEHEKKELQK------KQQLSAQLQPAQQQQQQ 3279
P S EL+ M ++ + + P I DL + ++ + K + ++ P Q
Sbjct: 319 PPMSDLELENMINATIKQDDPFNI-DLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPS 377
Query: 3280 QQQHSLLSAPGPAQAMS---LPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPA 3336
+ GPA +M+ L PS+ SQ Q G +R L Q +
Sbjct: 378 GSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRA------LPSWQEVS 431
Query: 3337 HALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQL 3396
HA Q + + Q H QH QQ QP +P S P
Sbjct: 432 HAQQLK----QIAANRQQHARMQQH--------QQQHQPT----NWSALPSSAGPSPGPF 475
Query: 3397 AMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVS 3456
++ + SF T F+ + P + G KVMA P +
Sbjct: 476 GQEKIPSPSFGQQT----FSPQSSPMP----GVAGGSGQSKVMANYMYKAGPSAQGGHLD 527
Query: 3457 LLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFH 3516
+L Q+ S N+ A +P Q P LFH
Sbjct: 528 VLMQQKPQDLSRSFINN-------PHPAMEPRQGNTKP-------------------LFH 561
Query: 3517 --TQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKI 3574
+ Q Q VL Q ++ S +Q+ ++ ++ + ++ + +QQ +
Sbjct: 562 FNSDQANQQMPSVLPSQ---NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 618
Query: 3575 QKQLD-QVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPG 3633
Q+Q ++QQ++ +++ A+ + +QQQQQQQQQQQQQQ PS P
Sbjct: 619 QQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQ-------PA 671
Query: 3634 QLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLA 3693
Q LP QP P L L + QP QQ+Q QHS G
Sbjct: 672 QSLPS---QPLLRSPLPLQQKLLL----QQMQNQPIAGMGYQVSQQQRQDQHS-VVGQNT 723
Query: 3694 GPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAI 3753
GPS P + S + +Q L QQ M Q LQ+Q +Q+QQ LL Q +
Sbjct: 724 GPS----PSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQL-LLQQQML 778
Query: 3754 QQQQQQGPGVQTNQALGPKP 3773
++ P Q N+ L P
Sbjct: 779 ADAEKIAPQDQINRHLSRPP 798
Score = 44.3 bits (103), Expect = 0.003
Identities = 68/312 (21%), Positives = 101/312 (32%), Gaps = 46/312 (14%)
Query: 3945 QQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAK 4004
Q Q Q Q + Q+ QQ +Q+ Q + QQQ Q A
Sbjct: 409 QSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPT----NWSAL 464
Query: 4005 PLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGE 4064
P SPG G ++ P+ + S+ G + MA +
Sbjct: 465 PSSAGPSPGPFG--------QEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYK 516
Query: 4065 VKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSS 4124
PS G +L+Q +PQ S P + +Q L H ++ Q+ S
Sbjct: 517 AGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLP 576
Query: 4125 SEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQG 4184
S+ +PS+ Q Q QQ ++ Q Q
Sbjct: 577 SQN--------KPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQ------------- 615
Query: 4185 LPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQ 4244
Q + Q + A+ Q + S QQQ Q Q+Q QQ Q +Q Q
Sbjct: 616 -----------QQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQ 664
Query: 4245 EPGTQTSPLQGL 4256
+P +Q P Q L
Sbjct: 665 QPSSQ--PAQSL 674
Score = 43.1 bits (100), Expect = 0.008
Identities = 69/255 (27%), Positives = 96/255 (37%), Gaps = 30/255 (11%)
Query: 4012 PGALGPTLLLTGKEQNTVDPAVSSEATEG-PSTHQGGPLAIGTTPE-SMATEPGEVKPSL 4069
P + GP + +T P S ++ P T G A+ + E S A + ++ +
Sbjct: 384 PPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANR 443
Query: 4070 SGDSQLLLVQPQPQPQ-----PSSLQLQP------PLRLPGQQQQQVSLLHTAGGGSHGQ 4118
+++ Q Q QP PSS P + P QQ S + G G
Sbjct: 444 QQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAG- 502
Query: 4119 LGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPV 4178
GSG S ++ + A PS G M Q PQ L R NN P P
Sbjct: 503 -GSGQSKVMANYMYK-AGPSAQGGHLDVLMQQK---PQD--LSRSFINN-------PHPA 548
Query: 4179 LQSGQGLPGVGIMPTVGQLRAQLQGVLAKN--PQLRHLSPQQQQQLQALLMQRQLQQSQA 4236
++ QG Q Q+ VL P L H + QQQQQ Q Q+Q QQ Q
Sbjct: 549 MEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQ 608
Query: 4237 VRQTPPYQEPGTQTS 4251
+Q Q+ Q+S
Sbjct: 609 QQQQQQQQQQQQQSS 623
Score = 42.7 bits (99), Expect = 0.010
Identities = 156/732 (21%), Positives = 247/732 (33%), Gaps = 153/732 (20%)
Query: 2190 PTAPPTYPPYPSPTGAPAQPP------------MLGASSRPGAGQPGEFHTTPPGTPRHQ 2237
P PP PP S A A PP +L +S+ G+G P TP Q
Sbjct: 105 PPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQ 164
Query: 2238 PSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFG-ESRKALEVKKEELGASS 2296
++ L+ SL V P S P G L++K+ +G +
Sbjct: 165 RNSALIALQG---SLKRKQVVNL---------SPANSKRPNGFVDNSFLDIKRIRVGENL 212
Query: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPG-----LGLRPQE 2351
S G L +++ S G L + + K P + SPG +GL+ +
Sbjct: 213 -SAGQGGLQ-INNGQSQIMSGTLPMSQAPLRKTNTLPSHTH----SPGNGLFNMGLKEVK 266
Query: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLP------- 2404
P + L+ S + + + + Y P P E L S+P
Sbjct: 267 KEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLEL 326
Query: 2405 ----------SDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPP 2454
DPF+ + QSQ S+ P P SP + S P RPP
Sbjct: 327 ENMINATIKQDDPFN-IDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPP 385
Query: 2455 SRPQ--SRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGG---FPAALPAGPAGEL--- 2506
S S A P P P+ S A G+G P+ A +L
Sbjct: 386 SAGPAFSMANSALSTSSPIPSVPQ------SQAQPQTGSGASRALPSWQEVSHAQQLKQI 439
Query: 2507 ------HAKVPSGQ----PPNFVRSPGTGAFVGTPSPMRFTFPQ----AVGEPSLKPPV- 2551
HA++ Q P N+ P + PSP F + + G+ + P
Sbjct: 440 AANRQQHARMQQHQQQHQPTNWSALPSSAG----PSPGPFGQEKIPSPSFGQQTFSPQSS 495
Query: 2552 PQPGLPPPHG-----INSHFGPGPTLG----------KPQSTNYTVATGNFHPSGSPLGP 2596
P PG+ G N + GP+ KPQ + + N HP+ + P
Sbjct: 496 PMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFIN-NPHPA---MEP 551
Query: 2597 SSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGS-- 2654
G+T + + + +P P + P L H Q+ ++++
Sbjct: 552 RQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQ 611
Query: 2655 ----------SLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEK 2704
S +A+ Q +S Q + ++Q+Q+Q+ +QQ Q+ +Q++
Sbjct: 612 QQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQ------QQQQQQQQQQQQQ 665
Query: 2705 ETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAG---------TQDKSSLVGLPPSK 2755
++ A P P P AG QD+ S+VG
Sbjct: 666 PSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVG----- 720
Query: 2756 LSGPILGPGSFPSDDRLSRPPPPA--TPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQ 2813
G PS + S P + S + ++QL+G Q ++ + +Q
Sbjct: 721 -----QNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQ--------IMEQ 767
Query: 2814 QQQLWQQQQATA 2825
+QQL QQQ A
Sbjct: 768 KQQLLLQQQMLA 779
Score = 36.6 bits (83), Expect = 0.71
Identities = 178/882 (20%), Positives = 280/882 (31%), Gaps = 156/882 (17%)
Query: 3186 GATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGG-PAASGDELDKMESSLVASE 3244
G T GP P +GP F + + AL+ P+ + S +
Sbjct: 371 GLTQGPSGSPQLRPPSAGPA-------FSMANSALSTSSPIPSVPQSQAQPQTGSGASRA 423
Query: 3245 LPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPA------------ 3292
LP E + K++ +Q A++Q QQQ Q +L S+ GP+
Sbjct: 424 LPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSP 483
Query: 3293 ---QAMSLPHEGSSPSLAGSQQQLSL------GLAGARQPGLPQPLMPTQPPAHALQQRL 3343
Q P P +AG Q + + Q G LM +P +
Sbjct: 484 SFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFIN 543
Query: 3344 APSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLA 3403
P AM QG+ H Q++Q + S P P + QQ QQQ
Sbjct: 544 NPHPAMEPRQGNTKPLFHFNS-----DQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQ 598
Query: 3404 NSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLS 3463
+ + ++ Q S A +QQ S+ AQ+
Sbjct: 599 QQQQQQQQQQQQQQQQ----------------QQQQQQQSSISAQQQQQQQSSISAQQQQ 642
Query: 3464 GGPSSDLQNHVAAGSGQERSAGDP-SQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQ 3522
Q Q++ P SQP + P +Q ++ Q + L QQ+
Sbjct: 643 QQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLP--SQPLLRSPLPLQQKLLL---QQMQN 697
Query: 3523 MQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVR 3582
+ + Q+ ++ + Q T + QQS + +QL +
Sbjct: 698 QPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQL--MG 755
Query: 3583 KQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQ 3642
K+Q +M +Q+QQ QQQ A Q R L++ P P + Q
Sbjct: 756 KKQTLQRQIM-------EQKQQLLLQQQMLADAEKIAPQDQINRHLSRPP----PDYKDQ 804
Query: 3643 PPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPG 3702
R G M Q Q+SGG+ +++ S
Sbjct: 805 -------------RRNVGNM-----------------QPTAQYSGGSSTISLNSNQALAN 834
Query: 3703 NLALRS-LGPDSRLLQER------QLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQ 3755
++ + L P+S LL L Q M + L Q + Q+ Q+
Sbjct: 835 PVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQR 894
Query: 3756 QQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHP 3815
+Q Q N + P+P L P +++ G V QQ P
Sbjct: 895 NPKQLLANQNNPMM-PRPPTLGPSNNNN---------------VATFGAGSVGNSQQLRP 938
Query: 3816 GALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSH 3875
+T S P Q+ +M TA Q+ G S
Sbjct: 939 N------------LTHSMASMPP---QRTSNVMITSNTTAPNWASQE---------GTSK 974
Query: 3876 LQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQ 3935
Q++L S + P G+ Q LQQ QQ Q+ + QL Q +
Sbjct: 975 QQEALTSAGVR-----FPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQL--TPAVQMR 1027
Query: 3936 QQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV 3995
Q+ Q Q + L + Q Q Q G LNQSRT ++
Sbjct: 1028 PMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTG-LNQSRTGINQPPSLTPSN 1086
Query: 3996 ALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEA 4037
P ++ Q L L ++ + + PA++S+A
Sbjct: 1087 FPSPNQSSRAFQGTDHSSDLAFDFL--SQQNDNMGPALNSDA 1126
Score = 36.2 bits (82), Expect = 0.93
Identities = 43/181 (23%), Positives = 66/181 (36%), Gaps = 27/181 (14%)
Query: 969 PESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLL 1028
P P+ ++++ SP T P + PPS G A+ L P P
Sbjct: 355 PSLPMEKIVIKSEYSP----GLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVP-- 408
Query: 1029 QHSLVPQN-SPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE 1087
Q PQ S S+ P +S L K + + + + ++ +P +
Sbjct: 409 QSQAQPQTGSGASRALPSWQEVSHAQQL----KQIAANRQQHARMQQHQQQHQPTNWSAL 464
Query: 1088 PSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASE 1147
PS+ P P P G P+PS G+ T +P S P PG GS S+
Sbjct: 465 PSSAGPSPGPFGQEKIPSPS----------FGQQTF------SPQSSPMPGVAGGSGQSK 508
Query: 1148 L 1148
+
Sbjct: 509 V 509
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 141 bits (355), Expect = 2e-32
Identities = 163/592 (27%), Positives = 228/592 (38%), Gaps = 131/592 (22%)
Query: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPA---------S 477
+P++ P P P P P PPP P PPP S P A +
Sbjct: 612 QPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTIT 671
Query: 478 PLPEALHLSRPLEESPLSP-------------------PPEESPLSPPPESSPFSPLEES 518
L A S L + P P PP P PP S + L+ +
Sbjct: 672 RLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA 731
Query: 519 PLSP--PEESPPSPALE-------TPLSPPPEASPLSPPFEESPLSP--PPEELPTSPPP 567
P +P P+ S P P L+ T ++PP +P PP +PL P PP+ L T P P
Sbjct: 732 PCAPSLPQFSAPPPPLKIHQVQHITQVAPP---TPPPPPPIPAPLPPQAPPKPLVTIPAP 788
Query: 568 EASRL-------SPPPEESPMSPPPEESPMSP----PPEASRLFPPFEESPLSPP----- 611
+++ + PP +P PP ++ P P PP PP P+ PP
Sbjct: 789 TSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS-----PPTPPVPVPPPTLPKQ 843
Query: 612 ------PEESPLSPPPE-----ASRLSPPP-----EDSPMSP-PPEESPMSPPPEVSRLS 654
P SPLSP P AS+ PPP E P+ P P +P SPP ++
Sbjct: 844 QSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPK 903
Query: 655 ------PLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708
P+P PPPE S + PPP P SP P +PPP PT+ P D S
Sbjct: 904 WQPSSIPVPSPDFPPPPPESSLVFPPP---PPSPVP-----APPPPPPPTASPTPDKSGS 955
Query: 709 PPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP 768
P + S S P + P P P+ S G P P+ P + + +P AE
Sbjct: 956 PGKKTSKTSSPGGKKP-PPTPQRNSSIKSSSGAE-HPEPKRPSVDSLVSK--FTPPAES- 1010
Query: 769 HLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP---VPEEPCLS 825
P + L P P P+P +L+LS L + P LS
Sbjct: 1011 ------------GSPSKETLPP----PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLS 1054
Query: 826 PQPEESHL---SPQSEEPCLSPRPEESHLSPELEKPPL-----SPRPEKPPEEPGQCPAP 877
+ ++S + SP S+ P PE P +E P + SP+ +P Q +
Sbjct: 1055 GRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQW-SK 1113
Query: 878 EELPLFPPPGEPSL--SPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927
+ PPP P S L + +SE +P ++ + ++P SP S+ P
Sbjct: 1114 MSVKKAPPPTRPKRNDSTRLTQAEISE--QPTMATVVPQVPTSPKSSLSVQP 1163
Score = 134 bits (336), Expect = 3e-30
Identities = 154/570 (27%), Positives = 213/570 (37%), Gaps = 95/570 (16%)
Query: 515 LEESPLSPPEE-SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLS 573
LEES + E + P +L PLSP P+ + SP PPP P PPP
Sbjct: 587 LEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPP------ 640
Query: 574 PPPEESPMSPPPEESPMSPPPEASRLFPPF--------------EESPLSPPPEESPLSP 619
PPP PPP P P A P F L PP +
Sbjct: 641 PPP------PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQS 694
Query: 620 PPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESP 679
++ PP PPP P +P +++L P P P S PP
Sbjct: 695 QSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA------PSLPQFSAPPPPLK 748
Query: 680 TSPPPEASRLSPPPEDSPTSPPPEDSPASP-PPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
++++PP +P PPP +P P P L+++P S P Q P +
Sbjct: 749 IHQVQHITQVAPP---TPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805
Query: 739 EGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ-PEEPCLCAVPEEPHLSPQAEGPHL 797
P + P ++P P P P P P P++ CA P LSP P +
Sbjct: 806 PTPPVPPAKKQPAF-PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPV---PSV 861
Query: 798 SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEK 857
Q ++ Q P P E L P P ++++PQS P + +P+ S +
Sbjct: 862 VKQ-----IASQFPPPPTPPAMESQPLKPVP--ANVAPQS-PPAVKAKPKWQPSSIPV-- 911
Query: 858 PPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPL 917
P P+ PP P PE +FPPP P PA P P SP P++
Sbjct: 912 ----PSPDFPP------PPPESSLVFPPP------PPSPVPAPPPPPPPTASPTPDK--- 952
Query: 918 SPSGEP--SLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAA 975
SG P S P PPP T ++ E+P +P+ P +
Sbjct: 953 --SGSPGKKTSKTSSPGGKKPPP-----TPQRNSSIKSSSGAEHP-------EPKRP-SV 997
Query: 976 PILETPISPPPEANCTDPEPVPPMILPPSPG--SPVGPASP-ILMEPLPPQCSPLL---- 1028
L + +PP E+ E +PP PP PG + G P +L + +P+L
Sbjct: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057
Query: 1029 QHSLVPQNSPPSQCSPPALPLSVPSPLSPI 1058
+ S+V SPPS P P PL PI
Sbjct: 1058 KDSVVEFPSPPSDSDFPPPPPETELPLPPI 1087
Score = 131 bits (330), Expect = 2e-29
Identities = 180/688 (26%), Positives = 256/688 (37%), Gaps = 131/688 (19%)
Query: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPL--SPPPEASPLSPPF- 549
PLSP P+ ++P S P PL P PP PP P PL P A +P F
Sbjct: 608 PLSPQPKI--VTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFV 665
Query: 550 ---------EESPLSPPPEELPTSPPPEASRLSPP---PEESPMSPPPEESPMSPPPEAS 597
S S + PT P ++ + P P + PPP P PPP
Sbjct: 666 KYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP---PPPPPPTPG 722
Query: 598 RLFPPFEESPLSPPPEESPLSPPP-------EASRLSPPPEDSPMSPPPEESPMSP---- 646
+ +P +P + PPP ++++PP +P PPP +P+ P
Sbjct: 723 SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPP---TPPPPPPIPAPLPPQAPP 779
Query: 647 ------PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSP 700
P S + PVV++ +PP P+ PP ++ P P AS + P SP +P
Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV-PPAKKQPAFP---ASYIPP----SPPTP 831
Query: 701 PPEDSPASPPPEDSLMSLPLEESPLLPLPE-EPQLCPRSEGPHLSPRPEEPHLSPRPEEP 759
P P + P + S + P SPL P+P Q+ + P P E L P P
Sbjct: 832 PVPVPPPTLPKQQSFCAKP-PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP--A 888
Query: 760 HLSPQAEEPHLSPQPE-EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPV 818
+++PQ+ P + +P+ +P VP P P P PE + P P SPV
Sbjct: 889 NVAPQS-PPAVKAKPKWQPSSIPVP-SPDFPP--------PPPESSLVFP---PPPPSPV 935
Query: 819 PEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPE 878
P P P P P SP P++S + SP +KPP P + + +
Sbjct: 936 PAPP---PPP----------PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIK 982
Query: 879 EL--PLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
P P PS+ L+ + + P E SP E LP P+ P + LP
Sbjct: 983 SSSGAEHPEPKRPSVDSLVSK--FTPPAESG-SPSKETLP-PPAAPPKPGKLNLSGVNLP 1038
Query: 937 PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV 996
L +A P LS G+ DS E P SPP +++ P P
Sbjct: 1039 GVLQQGCVSAKAPVLSGRGK---------DSVVEFP----------SPPSDSDFPPPPPE 1079
Query: 997 PPMILPP--SPGSPVGPASP--ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP 1052
+ LPP P G SP ++ P P Q S + P P S
Sbjct: 1080 TELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRL------ 1133
Query: 1053 SPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPA--- 1109
+AE+ E T P+ P S+ S P + DL+ +
Sbjct: 1134 -------------TQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITR 1180
Query: 1110 -PALDDFSGLGEDTAPLDGIDAPGSQPE 1136
+L E TA +D + P PE
Sbjct: 1181 HGSLSSRMSRAEPTATMDDMALPPPPPE 1208
Score = 103 bits (256), Expect = 6e-21
Identities = 154/639 (24%), Positives = 220/639 (34%), Gaps = 106/639 (16%)
Query: 648 PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA 707
P S + PL ++ P S SPP P PPP PPP P+ P A
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660
Query: 708 SP-----PPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS 762
+P L + L P P + +S P + P P P P +
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 763 PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH-LSPQTEEPHLSPVPEE 821
P + L P P P L PQ P P P ++H + T+ +P P
Sbjct: 721 PGSAMAQLKPAPCAPSL----------PQFSAP---PPPLKIHQVQHITQVAPPTPPPPP 767
Query: 822 PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELP 881
P +P P ++ P P +P ++ + P +P P PP ++ P
Sbjct: 768 PIPAPLPPQAPPKPLVTIP--APTSTKTVAPVVTQAAPPTPTPPVPP--------AKKQP 817
Query: 882 LFP----PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL---MPPDP 934
FP PP P +P + P + P + P PLSP PS+ Q+ PP P
Sbjct: 818 AFPASYIPPSPP--TPPVPVPPPTLPKQQSFCAKPPPSPLSP--VPSVVKQIASQFPPPP 873
Query: 935 LPP-----PLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEAN 989
PP PL P+ AP P + A P + P P +
Sbjct: 874 TPPAMESQPLKPVPANVAP------------------QSPPAVKAKPKWQPSSIPVPSPD 915
Query: 990 CTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVP-----QNSPPSQCSP 1044
P P ++ PP P SPV PA P P PP SP S P + S P P
Sbjct: 916 FPPPPPESSLVFPPPPPSPV-PAPP---PPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP 971
Query: 1045 PALPLSVPSPLSPIGKVVGVSDEAELHEMETE-----KVSEPECPALEPSATSPLPSPMG 1099
P P S S G + + ++ + P L P A P P +
Sbjct: 972 PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLN 1031
Query: 1100 DLSCPAP---------SPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKG 1150
P + AP L SG G+D+ ++ P + P +EL
Sbjct: 1032 LSGVNLPGVLQQGCVSAKAPVL---SGRGKDSV----VEFPSPPSDSDFPPPPPETELP- 1083
Query: 1151 SPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISN 1210
L P E+ V P+ Q + +AP PPT K N+ +
Sbjct: 1084 ----LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAP----PPTRPKR---NDSTR 1132
Query: 1211 LSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVS 1249
L+Q + S P ++ SLS++ G D++
Sbjct: 1133 LTQAEISEQ-PTMATVVPQVPTSPKSSLSVQPGFLADLN 1170
Score = 96.7 bits (239), Expect = 6e-19
Identities = 172/673 (25%), Positives = 231/673 (34%), Gaps = 108/673 (16%)
Query: 2173 SQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPG 2232
S P + P +P P PP PP P P P PP L + S P AG
Sbjct: 610 SPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669
Query: 2233 TPRHQPSTPDP---FLKPRCPSLDNLAV-PESPGVGGGKASEPLLSPPPFGESRKALEVK 2288
R Q ++ F P P + + +V P+ G P PPP ++K
Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLK 729
Query: 2289 KEELGASSPSY-GPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGL 2347
S P + PP + T + P APL P+A P P + +
Sbjct: 730 PAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA----PPKPLVTI 785
Query: 2348 ------RPQEPPPAQALAPS-----PPSHPDIFRPGSYTDPYAQPPLTPRPQPPP----P 2392
+ P QA P+ PP+ P SY P PP P P PPP
Sbjct: 786 PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP--SPPTPPVPVPPPTLPKQ 843
Query: 2393 ESCCALPPRSLPSDPF--------SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPV--TP 2442
+S CA PP S P P S+ P P + PL P P + P V P
Sbjct: 844 QSFCAKPPPS-PLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKP 902
Query: 2443 RFQS-----PDPYSRPPSRPQSR-----DPFAPLHKPPRPQPPEVA---FKAGS----LA 2485
++Q P P PP P+S P +P+ PP P PP + K+GS +
Sbjct: 903 KWQPSSIPVPSP-DFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTS 961
Query: 2486 HTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP 2545
TS G P P P K SG + P + V +FT P G P
Sbjct: 962 KTSSPGGKKP---PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS-----KFTPPAESGSP 1013
Query: 2546 SLKPPVPQPGLPPPHGINSHFG---PGPTLGKPQSTNYTVATGNFHPS--GSPLGPSSGS 2600
S K +P P PP G + G PG S V +G S P PS
Sbjct: 1014 S-KETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSD-- 1070
Query: 2601 TGESYGLSPLRPPSVLPPPAPDGSLPYLS-HGASQRSGITSPVEKREDPGTGMGSSLATA 2659
S PPP P+ LP + SG TSP +P S ++
Sbjct: 1071 -------------SDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVK 1117
Query: 2660 ELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGS 2719
+ P P K+ RL + I +Q T+ + T+ ++ +V PG
Sbjct: 1118 KAPPPTRP-----------KRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSV-QPGF 1165
Query: 2720 WGAEPSSPAFEQLSR--------GQTPFAGTQDKSSLVGLPPSKLSGPI---LGPGSFPS 2768
+ + ++R + T D +L PP LS G
Sbjct: 1166 LADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISG 1225
Query: 2769 DDRLSRPPPPATP 2781
L R PPPA P
Sbjct: 1226 YATLRRGPPPAPP 1238
Score = 78.6 bits (192), Expect = 2e-13
Identities = 97/355 (27%), Positives = 138/355 (38%), Gaps = 46/355 (12%)
Query: 401 VTSMQPKEPGPLQCEAKPLGKAGVQLEPQ----LEAPLNEEMPLLPPPEESPLSPPPEES 456
+ S P P P E++PL + PQ ++A + +P P PPPE S
Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924
Query: 457 PTSPPPEASRL--SPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESS---- 510
PPP S + PPP ASP P+ SP ++ P +P SS
Sbjct: 925 LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSS 984
Query: 511 -------PFSPLEESPLS---PPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE 560
P P +S +S PP ES SP+ ET PPP A P S ++ P
Sbjct: 985 SGAEHPEPKRPSVDSLVSKFTPPAES-GSPSKET--LPPPAAPPKPGKLNLSGVNLPGVL 1041
Query: 561 LPTSPPPEASRLSPPPEESPM---SPPPEESPMSPPPEASRLFPPFEESPL---SPPPEE 614
+A LS ++S + SPP + PPPE PP E + + P+
Sbjct: 1042 QQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKV 1101
Query: 615 SPLSPPPEA-SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673
+ ++P P+ S++S P P +S E+S + V P +S LS
Sbjct: 1102 AVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSV 1161
Query: 674 PP-----------EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMS 717
P +S T +SR+S PT+ D A PPP L+S
Sbjct: 1162 QPGFLADLNRTLQRKSITRHGSLSSRMS---RAEPTA--TMDDMALPPPPPELLS 1211
Score = 70.5 bits (171), Expect = 4e-11
Identities = 121/482 (25%), Positives = 151/482 (31%), Gaps = 133/482 (27%)
Query: 2110 PGALGSPPPAAAPTIFIGSPTT---PAGLSTSADGFLKPPAG----------SVPGPDSP 2156
P + PPP P GS PA + S F PP V P P
Sbjct: 705 PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP 764
Query: 2157 GELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASS 2216
PP +PA +P Q P P T P PT P PP A
Sbjct: 765 P------PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP---AKK 815
Query: 2217 RPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAV--PESPGVGGGKASEPLLS 2274
+P P + P TP P P P P + P SP LS
Sbjct: 816 QPAF--PASYIPPSPPTP------PVPVPPPTLPKQQSFCAKPPPSP-----------LS 856
Query: 2275 PPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPR 2334
P P V K+ P PP + PL P
Sbjct: 857 PVP--------SVVKQIASQFPPPPTPPAME----------------------SQPLKPV 886
Query: 2335 ASQVEPQS-PGLGLRPQEPP-----PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ 2388
+ V PQS P + +P+ P P+ P PP +F P PP +P P
Sbjct: 887 PANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP---------PPPSPVPA 937
Query: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPL---------SAEAFCPSP 2439
PPPP PP + P+ S P S++SS P P S+ A P P
Sbjct: 938 PPPPP-----PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP 992
Query: 2440 VTPRFQSPDPYSRPP--SRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAA 2497
P S PP S S++ P PP+P G L +L P
Sbjct: 993 KRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP---------GKL---NLSGVNLPGV 1040
Query: 2498 LPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLP 2557
L G + AK P + G + V PSP + PP P+ LP
Sbjct: 1041 LQQGC---VSAKAP------VLSGRGKDSVVEFPSP--------PSDSDFPPPPPETELP 1083
Query: 2558 PP 2559
P
Sbjct: 1084 LP 1085
Score = 57.4 bits (137), Expect = 4e-07
Identities = 103/406 (25%), Positives = 136/406 (33%), Gaps = 93/406 (22%)
Query: 2354 PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP------RSLPS-- 2405
P +L P P I P YT PPL P P PPPP PP +S PS
Sbjct: 601 PYTSLVPPLSPQPKIVTP--YTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAG 658
Query: 2406 ---------DPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456
+R+ + Q + P TP + +++ P + P P PP
Sbjct: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPP 718
Query: 2457 PQSRDPFAPLHKPP---------RPQPPEVAFKAGSLAHTSLGA-------GGFPAALPA 2500
P A L P P PP K + H + A PA LP
Sbjct: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPP---LKIHQVQHITQVAPPTPPPPPPIPAPLPP 775
Query: 2501 GPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSP------MRFTFPQAVGEPS-LKPPVPQ 2553
+ +P+ V T A TP+P + FP + PS PPVP
Sbjct: 776 QAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPV 835
Query: 2554 P-----------GLPPPHGIN----------SHFGPGPTLG--------------KPQST 2578
P PPP ++ S F P PT PQS
Sbjct: 836 PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSP 895
Query: 2579 NYTVATGNFHPSGSPLGPSSG---STGESYGLSPLRPPSVL---PPPAPDGSLPYLSHGA 2632
A + PS P+ PS ES + P PPS + PPP P + P
Sbjct: 896 PAVKAKPKWQPSSIPV-PSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG 954
Query: 2633 S---QRSGITSPVEKREDPGTGMGSSLAT---AELPGTQDPGMSGL 2672
S + S +SP K+ P SS+ + AE P + P + L
Sbjct: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000
Score = 52.4 bits (124), Expect = 1e-05
Identities = 91/382 (23%), Positives = 131/382 (34%), Gaps = 80/382 (20%)
Query: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166
P P A+ + P +I + SP P S+ F PP VP P
Sbjct: 892 PQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPP------------ 939
Query: 2167 VPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEF 2226
P PPT P P +G+P + +S PG +P
Sbjct: 940 -----------------------PPPPPTASPTPDKSGSPGK--KTSKTSSPGGKKP--- 971
Query: 2227 HTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALE 2286
TP + S+ +P+ PS+D+L +P G S+ L PP
Sbjct: 972 PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPP---------- 1021
Query: 2287 VKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTP---RASQVEPQSP 2343
A+ P G NL SG +L G+ + KAP+ + S VE SP
Sbjct: 1022 -------AAPPKPGKLNL-------SGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSP 1067
Query: 2344 GLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSL 2403
PPP L P P +F T P + P+PQ S PP +
Sbjct: 1068 PSDSDFPPPPPETELPLPPIEIPAVF--SGNTSPKV-AVVNPQPQQWSKMSVKKAPPPTR 1124
Query: 2404 P----SDPFSRVPASPQSQSSSQSPLTP-RPLSAEAFCPSPV-----TPRFQSPDPYSRP 2453
P S ++ S Q ++ P P P S+ + P + T + +S +
Sbjct: 1125 PKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSL 1184
Query: 2454 PSRPQSRDPFAPLHKPPRPQPP 2475
SR +P A + P PP
Sbjct: 1185 SSRMSRAEPTATMDDMALPPPP 1206
Score = 51.2 bits (121), Expect = 3e-05
Identities = 166/788 (21%), Positives = 260/788 (32%), Gaps = 121/788 (15%)
Query: 3913 QQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQ 3972
+ Q Q + Q + Q + + ++ QL++ + + + +
Sbjct: 545 ESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTS 604
Query: 3973 QQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPA 4032
L Q + +++P Q L P P P P P + + P
Sbjct: 605 LVPPLSPQPK-IVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPM 663
Query: 4033 VSSEAT----EGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSS 4088
+T + S H G A+ P + VKP + ++ P P P P +
Sbjct: 664 FVKYSTITRLQNASQHSG---ALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 4089 LQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSM 4148
PG Q+ + A S+P A P Q +
Sbjct: 721 ---------PGSAMAQLK----------------PAPCAPSLPQFSAPPPPLKIHQVQHI 755
Query: 4149 TQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGI-MPTVGQLRAQLQGVLAK 4207
TQ + P P P PP P P+ P V I PT + A + A
Sbjct: 756 TQ--VAPPTPP----------PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP 803
Query: 4208 NPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQT-------SPLQGLLGCQ 4260
+ P ++Q + V PP P Q+ SPL +
Sbjct: 804 PTPTPPVPPAKKQPAFPASYIPPSPPTPPV-PVPPPTLPKQQSFCAKPPPSPLSPVPSVV 862
Query: 4261 PQLGG-FPGPQTGPLQE------LGAGPRPQGPPRLPAPPG-ALSTGPVLGPVHPTPPPS 4312
Q+ FP P T P E + A PQ PP + A P S+ PV P P PPP
Sbjct: 863 KQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPE 922
Query: 4313 SPQ--EPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLF 4370
S P PS +P+P P P PT P P + + + T
Sbjct: 923 SSLVFPPPPPSPVPAP-----------------PPPPPPTASPTPDKSGSPGKKTSKTSS 965
Query: 4371 SKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQS 4430
G P PP P+++S + +G PE + S+ + + S
Sbjct: 966 PGGKKP--PP-------TPQRNSSIKSS----SGAEHPEPKRPSVDSLVSKFTPPAESGS 1012
Query: 4431 VKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGH 4490
+E P AP L L+G +L Q + AK LS GRG + + +
Sbjct: 1013 PSKETLPPP-AAPPKPGKLNLSGVNLPG--VLQQGCVSAKAPVLS-GRGKDSVVEFPSPP 1068
Query: 4491 IDSKL--AGLEQKLQGTP--------SNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLR 4540
DS E +L P N A + P+P++ K S + + +
Sbjct: 1069 SDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVA--VVNPQPQQWSKMSVKKAPPPTRPK 1126
Query: 4541 KEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGAL 4600
+ D R ++A + + +++P + + SL G +N Q + G+L
Sbjct: 1127 RNDSTRLTQAEISEQPTMATVVP--QVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSL 1184
Query: 4601 PTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNG---VTPSEELGEHPKDAAS 4657
+ T ++++ PP PP L S QQK G ++ L P A
Sbjct: 1185 SSRMSRAEPTATMDDMALPPPPPELL------SDQQKAGYGGSHISGYATLRRGPPPAPP 1238
Query: 4658 ARDSERAL 4665
RD L
Sbjct: 1239 KRDQNTKL 1246
Score = 47.4 bits (111), Expect = 4e-04
Identities = 95/423 (22%), Positives = 140/423 (33%), Gaps = 73/423 (17%)
Query: 2409 SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHK 2468
+R+ + + +S PL+P+P + S +P P P PP P
Sbjct: 593 ARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP--------P 644
Query: 2469 PPRPQPPEVAFKAGS-------------LAHTSLGAGGF--PAALPAGPAGEL------- 2506
PP P P + A AGS L + S +G P P + +
Sbjct: 645 PPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP 704
Query: 2507 -HAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP------------SLKPPVPQ 2553
+ VP PP +PG+ P+P + PQ P + PP P
Sbjct: 705 PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP 764
Query: 2554 PGLPPPHGINSHFGPGP--TLGKPQSTNYT--VATGNFHPSGS-PLGPSSGSTGESYGLS 2608
P P P + P P T+ P ST V T P+ + P+ P+
Sbjct: 765 PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI 824
Query: 2609 PLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPG 2668
P PP+ P P P +LP Q+S P P + +A+ P P
Sbjct: 825 PPSPPTP-PVPVPPPTLP------KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPA 877
Query: 2669 MSGLSQTELEKQRQRQRLRELLIRQQIQRNTL---RQEKETAAAAAGAVGPPGSWGAEPS 2725
M + Q + + + Q +++ + + V PP P+
Sbjct: 878 MESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA 937
Query: 2726 SPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMD 2785
P + TP DKS G SK S P G P PP P SS+
Sbjct: 938 PPPPPPPTASPTP-----DKSGSPGKKTSKTSSP---GGKKP-------PPTPQRNSSIK 982
Query: 2786 VNS 2788
+S
Sbjct: 983 SSS 985
Score = 47.0 bits (110), Expect = 5e-04
Identities = 63/242 (26%), Positives = 85/242 (35%), Gaps = 42/242 (17%)
Query: 4754 DTKPYGALGLE-VPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSM--K 4810
DT+P G + + + + W++G E S S A +++N ++ LS K
Sbjct: 560 DTQPAGHVRSQSIVSSVFSEAWKRGTQLEES-----SKARMESMNRPYTSLVPPLSPQPK 614
Query: 4811 IPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKS-PDTGPDWLKQFDAVLPGYTL 4869
I Y P P P P L +S P G + P +
Sbjct: 615 IVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAG--------SAAPMFVK 666
Query: 4870 KSQLDILSLLKQESPA----PEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSP----- 4920
S + L Q S A P PP S + L PPP P PPP+P
Sbjct: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA 726
Query: 4921 -LAPSPASPPTEPLVELPTEPL-------------AEPPVPSPLPLASSPESARPKPRAR 4966
L P+P + P+ P P PL PP P P+P A P A PKP
Sbjct: 727 QLKPAPCA-PSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIP-APLPPQAPPKPLVT 784
Query: 4967 PP 4968
P
Sbjct: 785 IP 786
Score = 46.6 bits (109), Expect = 7e-04
Identities = 89/382 (23%), Positives = 127/382 (33%), Gaps = 66/382 (17%)
Query: 4619 PPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLA 4678
PP PP PP PPP + PS+ A R + + L
Sbjct: 634 PPPPPPPPPPPPPPPL---------PSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684
Query: 4679 ALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALS 4738
PTPP Q++ V+ + P+ +VP P P P GS + + +
Sbjct: 685 KPPTPPVMQSQSVKPQI---LVPPNGVVPPPPPP-------PPPPTPGSAMAQLKP---A 731
Query: 4739 PVIPLIPRASIP--------------VFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSV 4784
P P +P+ S P V P T P +P LP K
Sbjct: 732 PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP---PIPAPLPPQAPPKP------- 781
Query: 4785 MLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKG 4844
++T+ A + VA +++ P + P PA+ +P + P
Sbjct: 782 LVTIPAPTSTK------TVAPVVTQAAPPTPTP--PVPPAKK--QPAFPASYIPPSPPTP 831
Query: 4845 LEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILS-LLKQESPAPEPPTQHSYTY-----NV 4898
P T P + F A P L ++ + Q P P PP S NV
Sbjct: 832 PVPVPPPTLPKQ-QSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANV 890
Query: 4899 SNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSP-- 4956
+ + A P +PS P P P PP LV P P P P P P +SP
Sbjct: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTP 950
Query: 4957 -ESARPKPRARPPEEGEDSRPP 4977
+S P + +PP
Sbjct: 951 DKSGSPGKKTSKTSSPGGKKPP 972
Score = 40.4 bits (93), Expect = 0.049
Identities = 49/214 (22%), Positives = 75/214 (35%), Gaps = 10/214 (4%)
Query: 2767 PSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAA 2826
PS + S PPPP + + Q+ + P P LP Q + L T+
Sbjct: 735 PSLPQFSAPPPPLKIHQVQ-HITQVAPPTPP--PPPPIPAPLPPQAPPKPLVTIPAPTST 791
Query: 2827 TSMRFAMSARFPSTPGPEL--GRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNV 2884
++ ++ P TP P + ++ P + I P P PVP P P Q
Sbjct: 792 KTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPP 851
Query: 2885 QKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNN 2944
L P + Q +P P + + L+ + + P P+ P+
Sbjct: 852 PSPLSPVPSVVK-----QIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQP 906
Query: 2945 SLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNP 2978
S P P P P LV PP + + P P
Sbjct: 907 SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940
Score = 39.3 bits (90), Expect = 0.11
Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 12/106 (11%)
Query: 4885 APEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP 4944
+P+P YT + Q S P P P PPP P P P PP P P+ A P
Sbjct: 610 SPQPKIVTPYTAS-------QPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662
Query: 4945 -----PVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGV 4985
+ L AS A KP P + + +P L GV
Sbjct: 663 MFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGV 708
Score = 38.5 bits (88), Expect = 0.19
Identities = 34/141 (24%), Positives = 48/141 (34%), Gaps = 40/141 (28%)
Query: 4877 SLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASP-------- 4928
SL+ SP P+ T ++ + L PPP P PPP P PS ++P
Sbjct: 604 SLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPM 663
Query: 4929 -----------------------PTEPLVE---------LPTEPLAEPPVPSPLPLASSP 4956
PT P+++ +P + PP P P P
Sbjct: 664 FVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGS 723
Query: 4957 ESARPKPRARPPEEGEDSRPP 4977
A+ KP P + S PP
Sbjct: 724 AMAQLKPAPCAPSLPQFSAPP 744
Score = 33.9 bits (76), Expect = 4.6
Identities = 79/357 (22%), Positives = 115/357 (32%), Gaps = 68/357 (19%)
Query: 4619 PPTPPSSLPPTPPPSV-QQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSL-DL 4676
PP+PP+ P PPP++ +Q+ P L P S VK +
Sbjct: 825 PPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVP----------------SVVKQIASQ 868
Query: 4677 LAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRA 4736
PTPP MES P ++ P S P +W+
Sbjct: 869 FPPPPTPP-------AMESQPLKPVPANVAPQSPPAV-----------KAKPKWQPSSIP 910
Query: 4737 L-SPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAK- 4794
+ SP P P S VFP P P + GS S+ K
Sbjct: 911 VPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKK 970
Query: 4795 -------NLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEG 4847
N + + AE K P+ ++ +P P K P K G
Sbjct: 971 PPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPK--PG 1028
Query: 4848 KSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPA--PEPPTQHSYTYNVSNLDVRQ 4905
K +G + VL + ++ +LS ++S P PP+ +
Sbjct: 1029 KLNLSGVN----LPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFP---------- 1074
Query: 4906 LSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPK 4962
PPPE P P P+ S T P V + +P S + + +P RPK
Sbjct: 1075 --PPPPETELPLPPIEIPAVFSGNTSPKVAVVN---PQPQQWSKMSVKKAPPPTRPK 1126
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 139 bits (351), Expect = 6e-32
Identities = 121/321 (37%), Positives = 150/321 (46%), Gaps = 53/321 (16%)
Query: 3695 PSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQ 3754
P+ +PG L G + + +Q+ + Q+ +QQ QQ Q +LGQ ++
Sbjct: 1869 PTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVH 1928
Query: 3755 QQQQQGP-GVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAV--LQ 3811
Q G+QT+Q G P SH GL Q GP G + P + Q
Sbjct: 1929 QMTPSSSYGLQTSQ-------GYTPYVSHVGL-------QQHTGPAGTMVPPSYSSQPYQ 1974
Query: 3812 QQHPGALGPQGPHRQVLMTQSRVLSSPQ--LAQQGQGLMGHRLVTAQQQQQQQQHQQQGS 3869
HP L+ +R L Q GH L + Q+ Q
Sbjct: 1975 STHPST-------NPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQT------- 2020
Query: 3870 MAGLSHLQQSLMSHSGQPKLSAQPMG----SLQQLQQQQQLQQQQQLQQQQQQQLQQQQQ 3925
LQQ+ M + P +SAQ + S L +QQQ QQQQQ QQQQQQQ QQQQQ
Sbjct: 2021 ------LQQTPMISTMTP-MSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQ 2073
Query: 3926 LQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLL 3985
QQ ++QQQQQQ L+QQQQQQ QQQQQQ QQQQQQQQQQ Q QQQQQQ Q +
Sbjct: 2074 QQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQS 2133
Query: 3986 SPQ---------QQQQQQVAL 3997
PQ QQQQQ AL
Sbjct: 2134 QPQFQRQGLQQTQQQQQTAAL 2154
Score = 68.2 bits (165), Expect = 2e-10
Identities = 76/250 (30%), Positives = 96/250 (38%), Gaps = 45/250 (18%)
Query: 3683 QQHSGGAGSLAGPSGGFFPGNLALRSLGP----DSRLLQERQL-QLQQQRMQLAQKLQQQ 3737
QQH+G AG++ PS P S P +R LQ+R + QQ L
Sbjct: 1954 QQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
Query: 3738 QQ---QQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP 3794
Q+ Q QQ ++ + Q GV++ L P Q QQ Q
Sbjct: 2014 QRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAIL---------PEQQQQQQQQQQQQQQ 2064
Query: 3795 PQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVT 3854
Q Q Q + QQQ +Q+L Q + Q QQ Q
Sbjct: 2065 QQQQQQQQQQQQYHIRQQQ----------QQQILRQQQQQQQQQQQQQQQQ--------Q 2106
Query: 3855 AQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQ 3914
QQQQQQQQHQQ QQ + QP+ +QP Q LQQ QQ QQ L +
Sbjct: 2107 QQQQQQQQQHQQ----------QQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVR 2156
Query: 3915 QQQQQLQQQQ 3924
Q QQQL Q
Sbjct: 2157 QLQQQLSNTQ 2166
Score = 66.2 bits (160), Expect = 8e-10
Identities = 90/318 (28%), Positives = 116/318 (36%), Gaps = 81/318 (25%)
Query: 3596 RNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGH-GLQPPQGPPGGQAGG 3654
+ ++ +QQ QQ Q S+V ++PS S L T H GLQ GP G
Sbjct: 1907 QGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGP-----AG 1961
Query: 3655 LRLTPGGMALPGQPGGPFLNTAL--------------AQQQQQQHSGGAGSLAGPSGGFF 3700
+ P + P Q P N L QQ + G S S
Sbjct: 1962 TMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTL 2021
Query: 3701 PGNLALRSLGP-----------DSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLG 3749
+ ++ P + +L E+Q Q QQQ+ Q Q+ QQQQQQQQQQ H+
Sbjct: 2022 QQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR- 2080
Query: 3750 QVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAV 3809
QQQQQQ +L QQ Q Q Q Q
Sbjct: 2081 ----QQQQQQ-------------------------ILRQQQQQQQQQQQQQQQQQQQQQQ 2111
Query: 3810 LQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGS 3869
QQQH Q +Q Q + S PQ +QG QQ QQQQQ +
Sbjct: 2112 QQQQH-----QQQQQQQAAPPQPQPQSQPQFQRQG----------LQQTQQQQQ-----T 2151
Query: 3870 MAGLSHLQQSLMSHSGQP 3887
A + LQQ L + QP
Sbjct: 2152 AALVRQLQQQLSNTQPQP 2169
Score = 48.9 bits (115), Expect = 1e-04
Identities = 41/149 (27%), Positives = 70/149 (46%), Gaps = 10/149 (6%)
Query: 3480 QERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQ-LKVLEEQIGVHRKS 3538
Q+R +G Q PT+ G+ + QR + L T + M + Q GV
Sbjct: 1992 QQRPSGYVHQ---QAPTYGHGLTST--QRFSHQTLQQTPMISTMTPMSAQGVQAGVRST- 2045
Query: 3539 RKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKI-QKQLDQVRKQQKEHTNLMAEYRN 3597
A+ +Q+ ++ ++ + ++ + +QQ I Q+Q Q+ +QQ++ + +
Sbjct: 2046 --AILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQ 2103
Query: 3598 KQQQQQQQQQQQQQQHSAVLALSPSQSPR 3626
+QQQQQQQQQQQ QQ A P P+
Sbjct: 2104 QQQQQQQQQQQQHQQQQQQQAAPPQPQPQ 2132
Score = 42.0 bits (97), Expect = 0.017
Identities = 95/445 (21%), Positives = 140/445 (31%), Gaps = 64/445 (14%)
Query: 3815 PGALGPQGPHRQVLMTQSRVLSSPQLAQQ----GQGLMGHRLVTAQQQQQQQQHQQQGSM 3870
PGA P R+ T+ + S P + G G G VT H GS+
Sbjct: 1772 PGAAPPSTEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLLH--HPNPGSI 1829
Query: 3871 AGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQ 3930
L++ Q S+ ++ L A G + +L Q+ + +
Sbjct: 1830 THLNYRQGSIGLYTQNQPLPAG--GPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMG 1887
Query: 3931 LQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQ----QQQFQQQQQQQQMGL-LNQSRTLL 3985
L+ + + +QQQ + Q Q+ QQ QQ Q Q Q GL +Q T
Sbjct: 1888 LEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPY 1947
Query: 3986 SPQQQQQQQVA-----LGPGMPAKPLQHF---SSPGALGPTLLLTGKEQNTVDPAVSSEA 4037
QQ + P ++P Q ++P + PT L + V +
Sbjct: 1948 VSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYG 2007
Query: 4038 TEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRL 4097
ST + + TP P + +G ++ P+ Q Q Q Q +
Sbjct: 2008 HGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAIL-PEQQQQQQQQQQQQQQQQ 2066
Query: 4098 PGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQ 4157
QQQQQ H +L Q Q Q QQ
Sbjct: 2067 QQQQQQQQQQYHI---------------RQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQ 2111
Query: 4158 PMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQ 4217
+ Q PP+P P Q + Q QG+ Q
Sbjct: 2112 QQQQHQQQQQQQAAPPQPQPQSQP----------------QFQRQGL-----------QQ 2144
Query: 4218 QQQQLQALLMQRQLQQSQAVRQTPP 4242
QQQ Q + RQLQQ + Q P
Sbjct: 2145 TQQQQQTAALVRQLQQQLSNTQPQP 2169
Score = 41.6 bits (96), Expect = 0.022
Identities = 92/389 (23%), Positives = 141/389 (36%), Gaps = 45/389 (11%)
Query: 2333 PRASQVEPQSPGLGLRPQ-EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
PRA +EP L L P+ E PPA L P+ P P A PP T +
Sbjct: 1734 PRAYYLEP----LPLPPEDEEPPAPTLLEPEKKAPE---PPKTDKPGAAPPSTEERKKKS 1786
Query: 2392 PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP-----VTPRFQS 2446
+ RS P+ P +S P L P+P + R S
Sbjct: 1787 TKG----KKRSQPATKTEDYGMGP-GRSGPYGVTVPPDLLHH---PNPGSITHLNYRQGS 1838
Query: 2447 PDPYSRPPSRPQSR---DPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGF-PAALPAGP 2502
Y++ P DP+ P+ P + P + G L T G G P++
Sbjct: 1839 IGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYP-GVLPTTMTGVMGLEPSSYKTSV 1897
Query: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI 2562
+ VP GQ G +G S + T + G + + P G+
Sbjct: 1898 YRQQQPAVPQGQRLRQQLQQSQG-MLGQSSVHQMTPSSSYGLQTSQGYTPYVSHV---GL 1953
Query: 2563 NSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPD 2622
H GP T+ P ++ + HPS +P + + RP + AP
Sbjct: 1954 QQHTGPAGTMVPPSYSSQPYQST--HPSTNP------TLVDPTRHLQQRPSGYVHQQAPT 2005
Query: 2623 -----GSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTEL 2677
S SH Q++ + S + G G +TA LP Q Q +
Sbjct: 2006 YGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVR-STAILPEQQQQQQQQQQQQQQ 2064
Query: 2678 EKQRQRQRLRELL-IRQQIQRNTLRQEKE 2705
++Q+Q+Q+ ++ IRQQ Q+ LRQ+++
Sbjct: 2065 QQQQQQQQQQQQYHIRQQQQQQILRQQQQ 2093
Score = 40.8 bits (94), Expect = 0.038
Identities = 83/346 (23%), Positives = 122/346 (35%), Gaps = 60/346 (17%)
Query: 3089 VEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQ-----FTIATPKVEP 3143
+EP PL PE+ PPA EP + P PK ++ G P + T + +P
Sbjct: 1739 LEPLPLPPEDEEPPAPTLLEPEKKAPEP---PKTDKPGAAPPSTEERKKKSTKGKKRSQP 1795
Query: 3144 APAANSLGLGLKPGQS----MMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPS 3199
A G+G PG+S + D P S + + S G L T +
Sbjct: 1796 ATKTEDYGMG--PGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIG--------LYTQN 1845
Query: 3200 PLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKE 3259
GG + + LP P G L + ++ E + ++
Sbjct: 1846 QPLPAGGPRVDPYRPVRLPMQKLPTRPTYPG-VLPTTMTGVMGLEPSSYKTSVYRQQQPA 1904
Query: 3260 LQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSL-PHEGSSPSLAGSQQQLSLGLA 3318
+ + Q+L QLQ +Q Q H + P+ + L +G +P ++ Q G A
Sbjct: 1905 VPQGQRLRQQLQQSQGMLGQSSVHQMT----PSSSYGLQTSQGYTPYVSHVGLQQHTGPA 1960
Query: 3319 GARQPG--LPQPLMPTQP--------PAHALQQRLAPSM-AMVSNQGHMLSGQHGGQAGL 3367
G P QP T P P LQQR + + GH L+
Sbjct: 1961 GTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTS-------- 2012
Query: 3368 VPQQSSQPVLSQKPM-GTMPP-----------SMCMKPQQLAMQQQ 3401
Q+ S L Q PM TM P S + P+Q QQQ
Sbjct: 2013 -TQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQ 2057
Score = 40.8 bits (94), Expect = 0.038
Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Query: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQL 3313
+ ++++ Q++QQ Q Q QQQQQ QQQ +AP Q S P QQQ
Sbjct: 2091 QQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQ 2150
Query: 3314 SLGLAGARQPGLPQPLMPTQP 3334
+ L RQ L Q L TQP
Sbjct: 2151 TAAL--VRQ--LQQQLSNTQP 2167
Score = 39.3 bits (90), Expect = 0.11
Identities = 43/153 (28%), Positives = 55/153 (35%), Gaps = 41/153 (26%)
Query: 3594 EYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAG 3653
+ + +QQQQQQQQQQQQQQ + Q ++L + Q Q Q
Sbjct: 2054 QQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQ-------- 2105
Query: 3654 GLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDS 3713
QQQQQQH A P P S
Sbjct: 2106 ---------------------QQQQQQQQQQHQQQQQQQAAPP-----------QPQPQS 2133
Query: 3714 RLLQERQ-LQLQQQRMQLAQKLQQQQQQQQQQQ 3745
+ +RQ LQ QQ+ Q A ++Q QQQ Q
Sbjct: 2134 QPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166
Score = 37.0 bits (84), Expect = 0.55
Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 15/131 (11%)
Query: 3495 PTFAQGV--------INEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQ 3546
P AQGV I Q+Q ++ QQ Q Q + ++Q + ++ ++ + +Q
Sbjct: 2032 PMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQ 2091
Query: 3547 RTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQ 3606
+ ++ ++ + + QQ + Q+Q Q ++QQ + + + Q+Q QQ
Sbjct: 2092 QQQQQQQQQQQQQQQQ-------QQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQ 2144
Query: 3607 QQQQQQHSAVL 3617
QQQQQ +A++
Sbjct: 2145 TQQQQQTAALV 2155
Score = 35.4 bits (80), Expect = 1.6
Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 8/56 (14%)
Query: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP 558
L P P + PL PL P +E PP+P L P PE PP + P + PP
Sbjct: 1730 LRPRPRAYYLEPL---PLPPEDEEPPAPTLLEPEKKAPE-----PPKTDKPGAAPP 1777
Score = 35.4 bits (80), Expect = 1.6
Identities = 28/84 (33%), Positives = 37/84 (44%)
Query: 4196 QLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQG 4255
Q + Q Q + + Q + L QQQQQ Q Q+Q QQ Q +Q Q+ Q +P Q
Sbjct: 2070 QQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQP 2129
Query: 4256 LLGCQPQLGGFPGPQTGPLQELGA 4279
QPQ QT Q+ A
Sbjct: 2130 QPQSQPQFQRQGLQQTQQQQQTAA 2153
Score = 34.7 bits (78), Expect = 2.7
Identities = 32/123 (26%), Positives = 41/123 (33%), Gaps = 8/123 (6%)
Query: 3252 LLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQ 3311
+L ++++ Q++QQ Q Q QQQQQQQQ H + QQ
Sbjct: 2047 ILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQ 2106
Query: 3312 QLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQ 3371
Q Q Q P QP S QG + Q A LV Q
Sbjct: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQ--------SQPQFQRQGLQQTQQQQQTAALVRQL 2158
Query: 3372 SSQ 3374
Q
Sbjct: 2159 QQQ 2161
Score = 33.9 bits (76), Expect = 4.6
Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 11/59 (18%)
Query: 644 MSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP 702
+ P P L PLP+ PP +E P +PT PE PP D P + PP
Sbjct: 1730 LRPRPRAYYLEPLPL-----PPEDEEP------PAPTLLEPEKKAPEPPKTDKPGAAPP 1777
Score = 33.1 bits (74), Expect = 7.9
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 10/91 (10%)
Query: 493 PLSPPPEESPLSPPP----ESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPP 548
P P P + P P E S S LE+ LS + PS ++ P+ S SP
Sbjct: 631 PRPPSPFDDPADDPEHKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPT 690
Query: 549 FE-ESPLSPPPEELPTSPPPEASRLSPPPEE 578
E SP PE+ P + PPP+E
Sbjct: 691 MPCEGKGSPSPEK-----PDVEKEVKPPPKE 716
Score = 33.1 bits (74), Expect = 7.9
Identities = 41/165 (24%), Positives = 61/165 (36%), Gaps = 24/165 (14%)
Query: 787 HLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846
HL P+ +L P P L P+ EEP + E +P+P P++++P +P P
Sbjct: 1729 HLRPRPRAYYLEPLP----LPPEDEEPPAPTLLEPEKKAPEP------PKTDKPGAAP-P 1777
Query: 847 EESHLSPELEKPPLSPRPEKPPEEPGQCP---------APEELPLFPPPGE-PSLSPLLG 896
+ K +P E+ G P P +L P PG L+ G
Sbjct: 1778 STEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQG 1837
Query: 897 EPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP 941
L +P + P P P P Q +P P P + P
Sbjct: 1838 SIGLYTQNQPLPAGGPRVDPYRPVRLPM---QKLPTRPTYPGVLP 1879
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 137 bits (346), Expect = 2e-31
Identities = 159/513 (30%), Positives = 218/513 (42%), Gaps = 108/513 (21%)
Query: 3658 TPGGMALPGQPG-GPFLNTALAQQQQQQHSG-GAGSLAGPSGGFFPGNLALRSLGPDSRL 3715
TPG L + GP T + + Q + G G +L+G SGG S +
Sbjct: 6 TPGNRGLTARMEVGPATETFVLELQCLEDGGPGPDTLSGGSGG---------SESQEEEE 56
Query: 3716 LQERQLQLQQQRMQL---AQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPK 3772
QER Q+ + A ++ ++ + Q++ L QQ +Q P Q P+
Sbjct: 57 PQERNSSPQRPAVSAPVGASEIAEETRPGQRELQL-------QQLEQQPEPQQQ----PQ 105
Query: 3773 PQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQS 3832
+ L P H +L QP Q Q L Q Q++H Q H Q L +
Sbjct: 106 HEQLQQPQPHL-----ELQQQPQQDGQQQLSQLQ----QEKH------QSVHHQELKPEL 150
Query: 3833 RVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQ 3892
+++ Q Q QQ Q+QQ+ QQQ Q+ L + Q + Q
Sbjct: 151 QLMHQQQQLQP------------QQVQEQQRLQQQ---------QEQLQTQQAQEQQVLQ 189
Query: 3893 PMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ--------- 3943
LQQ Q+QQL QQQQ Q QQQQ LQQQ+QLQQQQ QQQQ+Q Q QQQ
Sbjct: 190 QQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQ 249
Query: 3944 -QQQQLQQQQQQLQQQQQQQQQQFQQQQ---QQQQMGLLNQSRTLLSPQQQQQQQVALGP 3999
QQQ LQQQQ QLQQQ +QQQ QQQ QQQ+ Q + LL QQ+Q QQ L P
Sbjct: 250 LQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQP 309
Query: 4000 GMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA 4059
P +P + L P L G EQ E + Q
Sbjct: 310 -PPLEPEEEEEVELELMPVDL--GSEQELEQQRQELERQQELERQQ-------------- 352
Query: 4060 TEPGEVKPSLSGDSQLL---LVQPQPQPQPSSLQLQ-PPLRLPGQQQQ------------ 4103
E +++ L + Q L L Q Q Q + +QL+ P+ L QQQ+
Sbjct: 353 -EQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPEL 411
Query: 4104 QVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQ 4136
Q+ L+ AGGG G+ ++ + +++ Q
Sbjct: 412 QLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQ 444
Score = 107 bits (266), Expect = 4e-22
Identities = 131/418 (31%), Positives = 176/418 (42%), Gaps = 104/418 (24%)
Query: 3569 EQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLL 3628
EQQ + Q+Q + QQ + E + + QQ QQQ Q QQ P L
Sbjct: 95 EQQPEPQQQPQHEQLQQPQPH---LELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQ 151
Query: 3629 TKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGG 3688
Q L +Q Q RL QQQQ+Q
Sbjct: 152 LMHQQQQLQPQQVQEQQ----------RL---------------------QQQQEQ---- 176
Query: 3689 AGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLL 3748
L + L Q+ QLQ Q Q QL LQQQQ+Q QQQQ L
Sbjct: 177 ---------------LQTQQAQEQQVLQQQEQLQQQVQEQQL---LQQQQEQLQQQQLLQ 218
Query: 3749 GQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVA 3808
Q +QQQQ Q Q + L + Q L+ QG L QQL Q Q A
Sbjct: 219 QQEQLQQQQFQ----QQQEQLQQQQQLLL--LQQQGQLQQQLLQQ------------QQA 260
Query: 3809 VLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQG 3868
LQQQ L Q AQ Q L+ + QQQQQQQ QQQ
Sbjct: 261 QLQQQ---------------------LLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQ 299
Query: 3869 SMAGLSHLQQSLMSHSGQPKLSAQPM----GSLQQLQQQ-QQLQQQQQLQQQQQQ---QL 3920
LQ + + ++ + M GS Q+L+QQ Q+L++QQ+L++QQ+Q QL
Sbjct: 300 EQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQL 359
Query: 3921 QQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLL 3978
+ Q++LQQ + Q +QQQQQL +QQ+ QL+ +L QQQ+ Q + Q + Q+ L+
Sbjct: 360 KLQEELQQLEQQLEQQQQQL-EQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELV 416
Score = 86.7 bits (213), Expect = 6e-16
Identities = 135/515 (26%), Positives = 197/515 (38%), Gaps = 101/515 (19%)
Query: 3809 VLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQG---LMGHRLVTAQQQQQQQQHQ 3865
+L Q PG G T++ VL L G G L G + Q++++ Q
Sbjct: 1 MLHQPTPGNRGLTARMEVGPATETFVLELQCLEDGGPGPDTLSGGS--GGSESQEEEEPQ 58
Query: 3866 QQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQ- 3924
++ S S + ++ + G +++ + ++LQ QQ QQ + QQ Q +QLQQ Q
Sbjct: 59 ERNS----SPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQP 114
Query: 3925 QLQQQQLQQQQQQQQLQQQQQQ--------------QLQQQQQQLQQQQQQQQQQFQQQQ 3970
L+ QQ QQ QQQL Q QQ+ QL QQQQLQ QQ Q+QQ+ QQQQ
Sbjct: 115 HLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQ 174
Query: 3971 QQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVD 4030
+Q L QQ Q+QQV + +Q LL +EQ
Sbjct: 175 EQ------------LQTQQAQEQQVLQQQEQLQQQVQE--------QQLLQQQQEQLQQQ 214
Query: 4031 PAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQ 4090
+ + Q + + L QLLL+Q Q Q Q LQ
Sbjct: 215 QLLQQQEQLQQQQFQ------------------QQQEQLQQQQQLLLLQQQGQLQQQLLQ 256
Query: 4091 LQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQ 4150
Q Q Q Q LL +A LL Q L Q Q
Sbjct: 257 QQ-------QAQLQQQLLE--------------QQQAQLQQQLLLQQQEQLQQQ---QQQ 292
Query: 4151 NLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQ 4210
LL QQ L++ Q +P P+ + + +MP +L+ + +
Sbjct: 293 QLLQQQQEQLQQ--------QQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELER 344
Query: 4211 LRHLSPQQQQQLQALLMQRQL----QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF 4266
+ L QQ+Q+ L +Q +L QQ + +Q QE + +P++ LG Q Q
Sbjct: 345 QQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVE--LGAQQQEVQL 402
Query: 4267 PGPQTGPLQELGAGPRP-QGPPRLPAPPGALSTGP 4300
P +L P G +P P A+ P
Sbjct: 403 ELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAP 437
Score = 70.5 bits (171), Expect = 4e-11
Identities = 128/518 (24%), Positives = 191/518 (36%), Gaps = 191/518 (36%)
Query: 3464 GGPSSDLQNHVAAGSG-------QERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFH 3516
GGP D + + GS QER++ P +P + P A + E Q E L
Sbjct: 35 GGPGPDTLSGGSGGSESQEEEEPQERNSS-PQRPAVSAPVGASEIAEETRPGQRELQLQQ 93
Query: 3517 TQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLV--------- 3567
+Q + Q + EQ+ ++ + L +Q+ + ++ + EK + V
Sbjct: 94 LEQQPEPQQQPQHEQL---QQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPEL 150
Query: 3568 -------------TEQQSKIQKQLDQVRKQQKEHTNLMA----------EYRNKQQQQQQ 3604
++Q ++Q+Q +Q++ QQ + ++ E + QQQQ+Q
Sbjct: 151 QLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQ 210
Query: 3605 QQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMAL 3664
QQQQ Q L Q + + QLL L QG
Sbjct: 211 LQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLL----LLQQQGQ----------------- 249
Query: 3665 PGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQ 3724
L L QQQQ Q +LL+++Q QLQ
Sbjct: 250 --------LQQQLLQQQQAQ--------------------------LQQQLLEQQQAQLQ 275
Query: 3725 QQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQG 3784
QQ + LQQQ+Q QQQQQ Q +QQQQ+Q
Sbjct: 276 QQLL-----LQQQEQLQQQQQ----QQLLQQQQEQ------------------------- 301
Query: 3785 LLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQG 3844
L QQL P PP P+ + V + P LG S +L QQ
Sbjct: 302 LQQQQLQP-PPLEPE-----EEEEVELELMPVDLG----------------SEQELEQQR 339
Query: 3845 QGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQ 3904
Q L QQ+ ++QQ Q+Q QL+ Q+
Sbjct: 340 QEL------ERQQELERQQEQRQ------------------------------LQLKLQE 363
Query: 3905 QLQQ-QQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQ 3941
+LQQ +QQL+QQQQQ QQ+ QL+ ++ QQQ++Q
Sbjct: 364 ELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQ 401
Score = 55.8 bits (133), Expect = 1e-06
Identities = 77/341 (22%), Positives = 133/341 (39%), Gaps = 40/341 (11%)
Query: 3502 INEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADA 3561
+ E + Q ++ TQQ + Q+ +EQ+ + ++ L +Q ++ +
Sbjct: 164 VQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQL 223
Query: 3562 EKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVL---- 3617
++ + +Q+ Q+Q + +QQ + + + + Q QQQ +QQQ Q +L
Sbjct: 224 QQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQ 283
Query: 3618 -ALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTA 3676
L Q +LL + QL PP P + L L P + +
Sbjct: 284 EQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQE--------- 334
Query: 3677 LAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQ--LQQQRMQLAQKL 3734
L QQ+Q+ L R ++RQLQ LQ++ QL Q+L
Sbjct: 335 LEQQRQE----------------------LERQQELERQQEQRQLQLKLQEELQQLEQQL 372
Query: 3735 QQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQ-GLMPPSSHQGLLVQQLSPQ 3793
+QQQQQ +QQ+ L ++ QQ + P+ Q L+P + G V
Sbjct: 373 EQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAGGGGAAVPGAPAA 432
Query: 3794 PPQGPQGMLGPAQVAVLQQ-QHPGALGPQGPHRQVLMTQSR 3833
P G + ++ VL P + GP +T +R
Sbjct: 433 VVVAPPGYVVVQELMVLPAVAAPAVVAIPGPAGSAALTPAR 473
Score = 51.2 bits (121), Expect = 3e-05
Identities = 112/487 (22%), Positives = 182/487 (37%), Gaps = 98/487 (20%)
Query: 3189 GGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLL 3248
GGP P LSG G S ++ E + P PA S + +S +A E
Sbjct: 35 GGPG-----PDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAP----VGASEIAEETRPG 85
Query: 3249 IEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAG 3308
+ E + Q +QQ Q QP +Q QQ Q H L P G
Sbjct: 86 -----QRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQ--------------QQPQQDG 126
Query: 3309 SQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMA-----MVSNQGHMLSGQHGG 3363
QQQLS Q Q L P H QQ+L P + Q + + Q
Sbjct: 127 -QQQLSQLQQEKHQSVHHQELKPELQLMHQ-QQQLQPQQVQEQQRLQQQQEQLQTQQAQE 184
Query: 3364 QAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDP 3423
Q L Q+ Q + ++ + + Q L Q+QL F +
Sbjct: 185 QQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQ----------EQ 234
Query: 3424 IAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERS 3483
+ + + + L + QG + + +QQ + L Q+L + LQ
Sbjct: 235 LQQQQQLLL-----LQQQGQL--QQQLLQQQQAQLQQQLLEQQQAQLQQ----------- 276
Query: 3484 AGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALC 3543
Q ++ + +Q Q ++ QQLLQ Q + L++Q +
Sbjct: 277 ---------------QLLLQQQEQLQQQQ----QQQLLQQQQEQLQQQ------QLQPPP 311
Query: 3544 AKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNL-MAEYRNKQQQQ 3602
+ ++ E D + + +Q+ ++++Q + R+Q++ L + E + +QQ
Sbjct: 312 LEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQ 371
Query: 3603 QQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPP-QGPPGGQAGGLRLTPGG 3661
+QQQQQ +Q L L+P + ++ +L P +QP Q AGG GG
Sbjct: 372 LEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTP---VQPELQLELVPAAGG-----GG 423
Query: 3662 MALPGQP 3668
A+PG P
Sbjct: 424 AAVPGAP 430
Score = 36.2 bits (82), Expect = 0.93
Identities = 40/166 (24%), Positives = 68/166 (40%), Gaps = 26/166 (15%)
Query: 3226 PAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQL-----SAQLQPAQQQQQQQ 3280
P +E +++E L+ +L E LE +++EL+++Q+L QLQ Q++ QQ
Sbjct: 310 PPLEPEEEEEVELELMPVDLGS--EQELEQQRQELERQQELERQQEQRQLQLKLQEELQQ 367
Query: 3281 QQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSL-----------------GLAGARQP 3323
+ L + + E + L QQ++ L G GA P
Sbjct: 368 LEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAGGGGAAVP 427
Query: 3324 GLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVP 3369
G P ++ PP + + Q L A+ + + G G A L P
Sbjct: 428 GAPAAVV-VAPPGYVVVQELMVLPAVAAPAVVAIPGP-AGSAALTP 471
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 135 bits (341), Expect = 9e-31
Identities = 240/890 (26%), Positives = 303/890 (34%), Gaps = 133/890 (14%)
Query: 329 GSAELNPNSEWFENYSLCHRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDAL 388
G A + P SE + LC+ KA T+ E CS SP E P
Sbjct: 85 GGAGVGPASEE-DMTKLCNHRRKAVAMATLYRSMET---TCSHSSPGEGAS-----PQMF 135
Query: 389 YVACQGQPKGGHVTSMQPKEP---GPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPE 445
+ G P + P P GP +P + Q P L P P L P
Sbjct: 136 HTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVS--QAFPTLAGPGGLFPPRLADPV 193
Query: 446 ESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP 505
S S P P P + PP L A L L S L PP S
Sbjct: 194 PSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSS 253
Query: 506 PPESSPFSPLEESPLSPPEESPPS---PALETPLSPPPEAS-PLSPPFEESPL-SPPPEE 560
PP P ++ PP PPS PA P S PP +S + P PL P E
Sbjct: 254 PPSDPPLFHCSDALTPPP--LPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVE 311
Query: 561 LPTSPPPEASRL---SPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPL 617
P +PP AS L + + P+ PP P +A P S P + P
Sbjct: 312 GPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQA----PSASHSSSLRPSQRRPR 367
Query: 618 SPPP-----EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP--LPVVSRLSPPPEESP 670
PP E P P +P P P S P + P L ++ +P P S
Sbjct: 368 RPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSD 427
Query: 671 LS----------PPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720
S PPP + PP+ P TS P +P P + P+
Sbjct: 428 GSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAP-PAASKAPV 486
Query: 721 EESPLLPLPEE------PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP 774
SP+L P E CP P L+ P SP + LS L P
Sbjct: 487 VPSPVLQSPSEGLGMGAGPACPL---PPLAGGEAFPFPSPE-QGLALSGAGFPGMLGALP 542
Query: 775 EEPCLCAVPEEPHLSPQ----AEGPHLSPQPEELHLSPQTEEPHLSP-VPEEP-----CL 824
L P P L+ G P PE L P P L+P PE P L
Sbjct: 543 LPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASL 602
Query: 825 SPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFP 884
P P L P P P + P L P + E E G P+ E P
Sbjct: 603 LPPPPSDLLPP----PSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGG-PSGE-----P 652
Query: 885 PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS----PSGEPSLSPQLMPPDPLPPPLS 940
G LSPLL P LS P P L L L + PSG P L P P PP S
Sbjct: 653 FSGLGDLSPLL-FPPLSAP--PTLIALNSALLAATLDPPSGTPPQPCVLSAPQP-GPPTS 708
Query: 941 PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMI 1000
+ TA P S LG+ A +S L +P+L + + + P +P ++
Sbjct: 709 SVTTATTDPGASSLGK------APSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLL 762
Query: 1001 LPPSP---GS------PVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSV 1051
PP P G P G A P L E P + LLQ +P P + C PP P S
Sbjct: 763 QPPGPLLSGQLGLQLLPGGGAPPPLSEASSP-LACLLQSLQIPPEQPEAPCLPPESPASA 821
Query: 1052 PSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPA 1111
P + + P AL P SP P P+ +L S
Sbjct: 822 LEP----------------------EPARPPLSALAPPHGSPDP-PVPELLTGRGSGKRG 858
Query: 1112 L---DDFSGLGEDTAPLDGIDAPGSQPEPGQ------TPGSLASELKGSP 1152
G+ + P G PGS+ EPG+ T G +++ SP
Sbjct: 859 RRGGGGLRGINGEARPARG-RKPGSRREPGRLALKWGTRGGFNGQMERSP 907
Score = 133 bits (335), Expect = 4e-30
Identities = 228/882 (25%), Positives = 295/882 (33%), Gaps = 178/882 (20%)
Query: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPM 590
++ET S SP + +SP P P++ PP + P P S PPE
Sbjct: 116 SMETTCSHSSPGEGASPQMFHT-VSPGP---PSARPPCRVPPTTPLNGGPGSLPPE---- 167
Query: 591 SPPPEASRLFPPFE-ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPE 649
PP S+ FP L PP P+ +S P ++P PP PPP
Sbjct: 168 --PPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPP------PPPA 219
Query: 650 VSRLSP-----LPVVSRLSPPPEESPLSPPPEESPTSPPPE---ASRLSPPPEDSPTSPP 701
+S +P + S L P SP +P SP S PP + L+PPP + P
Sbjct: 220 ISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLP 279
Query: 702 PEDSPASPPPEDSL-MSLPLEESPL--LPLPEEPQLCP-----------RSEGPHLSPRP 747
PAS PP S M LPL PL P E P P +++ P L P
Sbjct: 280 AHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPS 339
Query: 748 EEPHLSPRPEEPHLS------PQAEEPHLSPQPEEPCLCAVPEEPHLS-PQAEGPHLSPQ 800
PR + P S P P P P+ P S P+A P PQ
Sbjct: 340 TLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAP--VPQ 397
Query: 801 PEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPL 860
P L Q P + + P P + + + L P P S SP + P+
Sbjct: 398 PFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPI 457
Query: 861 SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE------------PPL 908
+P P G + +P P P S +P++ P L P E PPL
Sbjct: 458 --QPSLPGTTSGSLSS---VPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPL 512
Query: 909 S-------PLPEE-LPLSPSGEPSLSPQLMPPDPL-PPPLSPIIT---------AAAPPA 950
+ P PE+ L LS +G P + L P L PP SP++ P
Sbjct: 513 AGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPP 572
Query: 951 LSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPP----------MI 1000
PL L P G P P +L + PPP ++ P PP +
Sbjct: 573 PEPL--LPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLA 630
Query: 1001 LPPSPG-----------------SPVGPASPILMEPL--PPQCSPLLQHSLVPQNSPPSQ 1041
L P+ G S +G SP+L PL PP L L PPS
Sbjct: 631 LGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSG 690
Query: 1042 CSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL--PSPMG 1099
P LS P P P V + + + P P SPL S +G
Sbjct: 691 TPPQPCVLSAPQPGPPTSSVTTATTDPGASSLG----KAPSNSGRPPQLLSPLLGASLLG 746
Query: 1100 DLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEE 1159
DLS SP G+ P Q PG L S G +L
Sbjct: 747 DLSSLTSSP-----------------------GALPSLLQPPGPLLSGQLGLQLLPGGGA 783
Query: 1160 LAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASAS 1219
P++ C + Q P E+P AP P + S L A
Sbjct: 784 PPPLSEASSPLACLLQSLQIPP----EQPEAPCLPPE---------SPASALEPEPARPP 830
Query: 1220 FPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAI 1279
P GSPDP L+ G + R G LR G
Sbjct: 831 LSALAPPHGSPDPPVPELLT---GRGSGKRGRRGGGGLR-----------------GING 870
Query: 1280 SGGKAEGEKGRRRSSPARSRIKQGRSSSFPGR--RRPRGGAH 1319
A G K R P R +K G F G+ R PR H
Sbjct: 871 EARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHH 912
Score = 94.0 bits (232), Expect = 4e-18
Identities = 204/783 (26%), Positives = 255/783 (32%), Gaps = 114/783 (14%)
Query: 2216 SRPGAG-QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG---------G 2265
S PG G P FHT PG P +P P P +L PE P V G
Sbjct: 124 SSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLP-PEPPSVSQAFPTLAGPG 182
Query: 2266 GKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPD 2325
G L P P G S + + A SP+ PP +++PS P
Sbjct: 183 GLFPPRLADPVPSGGSSSPRFLPRGN--APSPAPPPPPAISLNAPSYNWGAALRSSLVPS 240
Query: 2326 VFKAPLTPRASQVEPQSPGL-----GLRPQEPPPAQALA--PSPPSHPDIFRPGSYTD-- 2376
+P P AS P P L L P PP+ L P P S P + +
Sbjct: 241 DLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLV 300
Query: 2377 --PYAQPPLTPRPQPPPPESCCAL--------PPRSLPSDPFSRVPASPQSQSSSQSPLT 2426
P P P PP + L PP PS R P + +S S L
Sbjct: 301 LGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLR 360
Query: 2427 P------RPLSAEAFCPS--PVTPRF---QSPDPYSRPPSRPQSRDPFAP----LHKPPR 2471
P RP + P TPR ++P P +P S P+ P P L P
Sbjct: 361 PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPT 420
Query: 2472 PQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTP 2531
P P S + S G A LP P + SG PP R P + GT
Sbjct: 421 PGP--------SHSDGSFNLLGSDAHLPPPPT------LSSGSPPQ-PRHPIQPSLPGTT 465
Query: 2532 SPMRFTFPQAVGEP--SLKPPVPQPGLPPP-HGINSHFGPGPTLGKPQSTNYTVATGNFH 2588
S + P A P S P VP P L P G+ G GP P +A G
Sbjct: 466 SGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLG--MGAGPACPLPP-----LAGGEAF 518
Query: 2589 PSGSP-LGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRED 2647
P SP G + G L L P L P P L + G G P E
Sbjct: 519 PFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLP 578
Query: 2648 PGTGMGSSLATAELPGTQDPGMSGLSQTELE----KQRQRQRLRELLIRQQIQRNTLRQE 2703
P G G LA E G S L + L + T
Sbjct: 579 PPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDG 638
Query: 2704 KETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGP 2763
+ +A A G G P S + S F LS T L+ L + L+ + P
Sbjct: 639 EGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPT----------LIALNSALLAATLDPP 688
Query: 2764 GSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQ-- 2821
P + P P P+S + G S +AP P Q L
Sbjct: 689 SGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSL--GKAPSNSGRPPQLLSPLLGASLLG 746
Query: 2822 QATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELR 2881
++ TS A+ + PGP L Q LG L LPG G P P + L
Sbjct: 747 DLSSLTSSPGALPSLL-QPPGPLLSGQ-LGLQL------LPGGGAPPPLSEASSPLACLL 798
Query: 2882 HNVQKGLGPGGTPFPGQGPPQRPRF--YPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPA 2939
++Q PP++P P L PE R + PP PP
Sbjct: 799 QSLQI-------------PPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPV 845
Query: 2940 PEL 2942
PEL
Sbjct: 846 PEL 848
Score = 68.6 bits (166), Expect = 2e-10
Identities = 137/508 (26%), Positives = 173/508 (34%), Gaps = 102/508 (20%)
Query: 2100 PALHLRIPPQPGALGSPPPAAAPTIFIGS----PTTPAGLSTSADGFLKPPAGSVPGPDS 2155
P+ L+ P + +G+ P P + G P+ GL+ S GF G++P P S
Sbjct: 488 PSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF-PGMLGALPLPLS 546
Query: 2156 PGELFLKLPPQVPAQVPSQDPFGLAPAY----PLEPRFPTAPPTYPPYPSPTGAPAQPPM 2211
G+ PP P+ + + FG+ P EP P PP P P G P P +
Sbjct: 547 LGQ-----PP--PSPLLNHSLFGVLTGGGGQPPPEPLLP--PPGGPGPPLAPGEPEGPSL 597
Query: 2212 LGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG-----GG 2266
L AS P PP PS P L L L G G GG
Sbjct: 598 LVASLLP----------PPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGG 647
Query: 2267 KASEPL-----LSP---PPFGESRKALEVKKEELGAS--SPSYGPPNLGFVDSPSSGTHL 2316
+ EP LSP PP + + L A+ PS PP + +P G
Sbjct: 648 PSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPT 707
Query: 2317 GGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPA---------QALAPSPPSHPD 2367
+ T D P AS + G PQ P +L SP + P
Sbjct: 708 SSVTTATTD-------PGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPS 760
Query: 2368 IFRP-GSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLT 2426
+ +P G L P PPP S + P L S Q P
Sbjct: 761 LLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACL--------------LQSLQIP-- 804
Query: 2427 PRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAH 2486
P EA C P +P +RPP AP H P P PE+ GS
Sbjct: 805 --PEQPEAPCLPPESPASALEPEPARPPL-----SALAPPHGSPDPPVPELLTGRGSGKR 857
Query: 2487 TSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPG--------TGAFVG--TPSPMRF 2536
G GG G GE A+ G+ P R PG G F G SP R
Sbjct: 858 GRRGGGGL-----RGINGE--ARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRT 910
Query: 2537 TFPQAVGEPSLKPPVPQPGLPPPHGINS 2564
Q GE L +P PPP G +S
Sbjct: 911 HHWQHNGE--LAEGGAEPKDPPPPGPHS 936
Score = 67.4 bits (163), Expect = 4e-10
Identities = 139/539 (25%), Positives = 179/539 (33%), Gaps = 125/539 (23%)
Query: 2485 AHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVG- 2543
+H+S G G P G A+ P PP + G G+ P + FP G
Sbjct: 122 SHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGP 181
Query: 2544 ----EPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPS--------- 2590
P L PVP G P + P P P + + + N+ +
Sbjct: 182 GGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSD 241
Query: 2591 -GSPLGPSSGSTGES----YGLSPLRPPSVLPP----PAPDG--SLPYLSHGASQRSGIT 2639
GSP P + S+ S + S P LPP PA G S P +S +
Sbjct: 242 LGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVL 301
Query: 2640 SPV---EKREDPGTG--MGSSLATA-----------------ELPGTQDPGMSGLSQTEL 2677
P+ E PG + SSL +A P Q P S S
Sbjct: 302 GPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRP 361
Query: 2678 EKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQT 2737
++R R+ + + T R+ + A A V P S EPS P +
Sbjct: 362 SQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPA---PVPQPFSL-PEPSQPILPSV----- 412
Query: 2738 PFAGTQDKSSLVGLPPSKLSGPILGPGSF---PSDDRLSRPPPPATPSSMDVNSRQLV-- 2792
SL+GLP GP GSF SD L PPPP S R +
Sbjct: 413 --------LSLLGLP---TPGPSHSDGSFNLLGSDAHL--PPPPTLSSGSPPQPRHPIQP 459
Query: 2793 ------GGSQAFYQRAPYPGSL--------PLQQQQQQLWQQQQATAATSMRFAMSARFP 2838
GS + AP P + P+ Q + A A FP
Sbjct: 460 SLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFP 519
Query: 2839 STPGPELGRQALGSPLAGISTRLPGP---GEPVPGPAGPAQFIELRHNVQKGL-GPGGTP 2894
P PE G G+ G+ LP P G+P P P L H++ L G GG P
Sbjct: 520 -FPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPL-------LNHSLFGVLTGGGGQP 571
Query: 2895 FP--------GQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPP------QKPSAPPA 2939
P G GPP P PEG L S LPP PSAPP+
Sbjct: 572 PPEPLLPPPGGPGPPLAPG-----------EPEGPSLLVASLLPPPPSDLLPPPSAPPS 619
Score = 66.2 bits (160), Expect = 8e-10
Identities = 179/740 (24%), Positives = 240/740 (32%), Gaps = 131/740 (17%)
Query: 2311 SSGTHLGGLE--LKTPDVFK----APLTPRASQVEPQSPG----LGLRPQEPPPAQALAP 2360
S GT GLE L P VF AP+TP + V P S L ++ L
Sbjct: 56 SDGTCKCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYR 115
Query: 2361 SPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSS 2420
S + PG P Q T P PP C +PP + P + P S +
Sbjct: 116 SMETTCSHSSPGEGASP--QMFHTVSPGPPSARPPCRVPPTT----PLNGGPGSLPPEPP 169
Query: 2421 SQSPLTPRPLSAEAFCPSPVTPRFQSPDPY---SRPPSRPQSRDPFAPLHKPPRPQPPEV 2477
S S P P PR P P S P P+ P P P PP +
Sbjct: 170 SVSQAFPTLAGPGGLFP----PRLADPVPSGGSSSPRFLPRGNAP-----SPAPPPPPAI 220
Query: 2478 AFKAGSLAH-TSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRF 2536
+ A S +L + P+ L + PA + PS PP F S A P P
Sbjct: 221 SLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPS-DPPLFHCSD---ALTPPPLPPSN 276
Query: 2537 TFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGP 2596
P G P+ +PPV + P + G PT+ P + + L
Sbjct: 277 NLPAHPG-PASQPPVSSATMHLPLVLGP-LGGAPTVEGPGAPPF-------------LAS 321
Query: 2597 SSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGT-----G 2651
S S PL PPS L P P SH +S R P R P G
Sbjct: 322 SLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRP---RRPPTVFRLLEG 378
Query: 2652 MGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAA 2711
G P P S E Q I + L +
Sbjct: 379 RGPQTPRRSRPRAPAPVPQPFSLPEPS--------------QPILPSVLSLLGLPTPGPS 424
Query: 2712 GAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDR 2771
+ G G++ P LS G P + SL G LS PG+ P+
Sbjct: 425 HSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSV---PGA-PAPPA 480
Query: 2772 LSRPPPPATPSSMDVNSRQLVG-----------GSQAFYQRAP----------YPGSLPL 2810
S+ P +P + +G G +AF +P +PG L
Sbjct: 481 ASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGA 540
Query: 2811 QQQQQQLWQQQQATAATSMRFAMSARF------------PSTPGPELGRQALGSPLAGIS 2858
L Q + F + P PGP L P ++
Sbjct: 541 LPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVA 600
Query: 2859 TRLPGP-GEPVPGPAGP-----AQFIEL----------RHNVQKGLGPGGTPFPGQGPPQ 2902
+ LP P + +P P+ P A F+ L + + GP G PF G G
Sbjct: 601 SLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLS 660
Query: 2903 RPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPT--- 2959
F P+S P +A LA + PP PP P + ++ P P T T T
Sbjct: 661 PLLFPPLSAPPTLIALNSAL-LAATLDPPS--GTPPQPCVLSAPQPGPPTSSVTTATTDP 717
Query: 2960 GLELVNRPPSSTELGRPNPL 2979
G + + PS++ GRP L
Sbjct: 718 GASSLGKAPSNS--GRPPQL 735
Score = 53.5 bits (127), Expect = 6e-06
Identities = 140/540 (25%), Positives = 181/540 (33%), Gaps = 115/540 (21%)
Query: 3987 PQQQQQQQVALGPG--MPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTH 4044
P Q GPG P + S G+ P L G + P + + PS +
Sbjct: 169 PSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYN 228
Query: 4045 QGG-------PLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQP-------------QP 4084
G P +G+ P A+ P L S L P P QP
Sbjct: 229 WGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQP 288
Query: 4085 QPSSLQLQPPLRL-----------PGQQQQQVS-LLHTAGGGSHGQL-------GSGSSS 4125
SS + PL L PG S LL A H L G +
Sbjct: 289 PVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRA 348
Query: 4126 EASSVPHLLA-QPSVSLGDQPGSMTQNL--LGPQQPMLERPMQNNTGPQP---PKPG-PV 4178
+A S H + +PS +P ++ + L GPQ P RP PQP P+P P+
Sbjct: 349 QAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPI 408
Query: 4179 LQSGQGLPGVGIMPTVGQLRAQ----LQGVLAKNPQLRHLS----PQQQQQLQALLMQRQ 4230
L S L G +PT G + L G A P LS PQ + +Q L
Sbjct: 409 LPSVLSLLG---LPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTT 465
Query: 4231 LQQSQAVRQTP--------PYQEPGTQTSPLQGL-LGCQPQL------GG----FPGPQT 4271
+V P P SP +GL +G P GG FP P+
Sbjct: 466 SGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQ 525
Query: 4272 GPLQE-------LGAGPRPQGPPRLPAPP-------GALSTG-------PVLGPVHPTPP 4310
G LGA P P + P P G L+ G P+L P P
Sbjct: 526 GLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGP 585
Query: 4311 PSSPQEPKRPSQL------PSPSSQLPTEAQLPPTHPGTPKP---QGPTLEPPPGRVSPA 4361
P +P EP+ PS L P PS LP + P + P GPT G A
Sbjct: 586 PLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGA 645
Query: 4362 AAQLADTLFSKGLGPWD----PPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQ 4417
+ GLG PP + T S+L+ LD +G P+ LS Q
Sbjct: 646 GGPSGEPF--SGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSG-TPPQPCVLSAPQ 702
Score = 53.5 bits (127), Expect = 6e-06
Identities = 133/518 (25%), Positives = 174/518 (33%), Gaps = 82/518 (15%)
Query: 3985 LSPQQQQQQQVALGPGMPAKPLQHFSS-PGALGPTLLLTGKEQNTVDPAVSSEATEGPST 4043
LS Q + + P +P SS PGA P P V S + PS
Sbjct: 445 LSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKA-------PVVPSPVLQSPSE 497
Query: 4044 HQG---------GPLAIGT-----TPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPS-S 4088
G PLA G +PE G P + G L L QP P P +
Sbjct: 498 GLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLN 557
Query: 4089 LQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSM 4148
L L G Q LL GG + V LL P L P +
Sbjct: 558 HSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAP 617
Query: 4149 TQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVG-IMPTVGQLRAQLQGVLAK 4207
NLL P+L G + G SG+ G+G + P + + ++A
Sbjct: 618 PSNLLASFLPLLALGPTAGDG-EGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIAL 676
Query: 4208 NPQL--RHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTS-PLQGLLGCQPQLG 4264
N L L P Q ++ A + PP T T+ P LG P
Sbjct: 677 NSALLAATLDPPSGTPPQPCVLS-------APQPGPPTSSVTTATTDPGASSLGKAPSNS 729
Query: 4265 GFPGPQTGPLQELGAG---------PRPQGPPRLPAPPGALSTGPV---LGPVHPTPPPS 4312
G P PL LGA P P L PPG L +G + L P PPP
Sbjct: 730 GRPPQLLSPL--LGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPL 787
Query: 4313 SPQEPKRPSQLPSPSSQLPTEAQ----LPPTHPGT---PKPQGPTLE---PPPGRVSPAA 4362
S E P S Q+P E LPP P + P+P P L PP G P
Sbjct: 788 S--EASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPV 845
Query: 4363 AQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREE 4422
+L L +G G ++ G L +NG+ P + K R E
Sbjct: 846 PEL---LTGRGSG--------------KRGRRGGGGLRGINGEARPARGR---KPGSRRE 885
Query: 4423 PCALGAQ-SVKREANGEPIGAPGTSNHLLLAGPRSEAG 4459
P L + + NG+ +P ++H G +E G
Sbjct: 886 PGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGG 923
Score = 47.4 bits (111), Expect = 4e-04
Identities = 181/815 (22%), Positives = 254/815 (31%), Gaps = 133/815 (16%)
Query: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPA 4291
Q V PP P + P L G L P P AGP PPRL
Sbjct: 133 QMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEP-PSVSQAFPTLAGPGGLFPPRLAD 191
Query: 4292 P-PGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPT 4350
P P S+ P P P P+ P P PS + + L P+ G+P +
Sbjct: 192 PVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHAS 251
Query: 4351 LEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEA 4410
PP P +D L P P +NL P A
Sbjct: 252 SSPPS---DPPLFHCSDALTPP---PLPPSNNLPAHPGP--------------------A 285
Query: 4411 SQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAK 4470
SQ + P LG G P P ++ LL A +++ L L+ +
Sbjct: 286 SQPPVSSATMHLPLVLGPLGGAPTVEG-PGAPPFLASSLLSAAAKAQHPPLPPPSTLQGR 344
Query: 4471 NVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASD 4530
+ S S L +++ + P+ R P TP+ R
Sbjct: 345 RPRAQAPSASHS----------SSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSR------ 388
Query: 4531 RLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQ 4590
R E L LSLL L P + + F GS +
Sbjct: 389 ----PRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPT 444
Query: 4591 LRGAFGSGALPTGPDYYSQL-LTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELG 4649
L GS P P S T +LS+ P P+ + P V ++ + +G
Sbjct: 445 LSS--GSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMG 502
Query: 4650 EHPKDAASARDSERALRDTSEVKSLDL--------LAALPTPPHNQTEDVRMESDEDSDS 4701
P A S + L L L ALP P + + S
Sbjct: 503 AGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLP---------LSLGQPPPS 553
Query: 4702 P---DSIVPASS-------PESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPV 4751
P S+ + PE +L P L G E ++ ++P P +P
Sbjct: 554 PLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPP 613
Query: 4752 FPDTKPYGALGLEVPGKLPVTTWEKGKGS----------------EVSVMLTVSAAAAKN 4795
P P L +P T G+GS ++S +L +A
Sbjct: 614 -PSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPT 672
Query: 4796 L----NGVMVAVAELLSMKIPNSYEVLFPE------SPARAGTEP---KKGEAEGPGGKE 4842
L + ++ A + S P + P+ S A T+P G+A G+
Sbjct: 673 LIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRP 732
Query: 4843 KGLEGKSPDTGPDWLKQFDAVL------------PGYTLKSQLDILSLLKQESPAPEPPT 4890
L SP G L ++ PG L QL + L +P PP
Sbjct: 733 PQL--LSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAP---PPL 787
Query: 4891 QHSYTYNVSNLDVRQLSAPPPEEPSPPP----SPLAPSPASPPTEPLVELPTEPLAEPPV 4946
+ + L Q+ PE P PP S L P PA PP L P +PPV
Sbjct: 788 SEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALA--PPHGSPDPPV 845
Query: 4947 PSPLPLASSPESARPKPRARPPEEGEDSRPPRLKK 4981
P L S + R GE +RP R +K
Sbjct: 846 PELLTGRGSGKRGRRGGGGLRGINGE-ARPARGRK 879
Score = 35.4 bits (80), Expect = 1.6
Identities = 62/233 (26%), Positives = 81/233 (34%), Gaps = 46/233 (19%)
Query: 3625 PRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQ 3684
P L + P Q P H +QP PG +G L PG A P P + + + Q +
Sbjct: 443 PTLSSGSPPQ--PRHPIQPSL--PGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEG 498
Query: 3685 HSGGAG------SLAGPSGGFFPG---NLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQ 3735
GAG LAG FP LAL G L + L L
Sbjct: 499 LGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGML----------GALPLPLSLG 548
Query: 3736 QQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPP 3795
Q L G + G G Q P P+ L+PP G L+P P
Sbjct: 549 QPPPSPLLNHSLFGVLT-------GGGGQ------PPPEPLLPPPGGPG---PPLAPGEP 592
Query: 3796 QGPQGMLGPAQVAVLQQQHPGAL--GPQGPHRQVLMTQSRVLSSPQLAQQGQG 3846
+GP + VA L P L P P +L + +L+ A G+G
Sbjct: 593 EGPSLL-----VASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEG 640
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 134 bits (337), Expect = 3e-30
Identities = 86/225 (38%), Positives = 120/225 (53%), Gaps = 25/225 (11%)
Query: 5336 TGCARSEPKILTHYK-RPHTLNSTSMSKAYQSTFTGETNTPY----SKQFVHSKSSQYRR 5390
TGCARSE K + LNS+ S T + P S + + S+ RR
Sbjct: 1701 TGCARSEGFYTIDKKDKLRYLNSSRASTDEPPADTQGMSIPAQPHASTRAGSERRSEQRR 1760
Query: 5391 LRTEW-----------------KNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRN 5433
L + + K + +S I GL+A + + MVIEY+G IR
Sbjct: 1761 LLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQ 1820
Query: 5434 EVANRREKIYEEQNRGI-YMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVTFDKED 5492
+A+ REK YE++ G YMFR++++ +IDAT G AR+INHSC PNC A+V+T + +
Sbjct: 1821 VIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQK 1880
Query: 5493 KIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN 5537
KI+I S + I EE+TYDY+F ED KIPC CG+ NCR +N
Sbjct: 1881 KIVIYSKQHINVNEEITYDYKFPIED--VKIPCLCGSENCRGTLN 1923
Score = 100 bits (249), Expect = 4e-20
Identities = 150/572 (26%), Positives = 218/572 (38%), Gaps = 120/572 (20%)
Query: 505 PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLS--PPPEELP 562
PP ++ P + PP ++ P+P ++ SP ++P++ PPP E P
Sbjct: 366 PPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSP-----------YQTPVAHFPPPPEEP 414
Query: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
T+ +R S +P PP PP E P +E P +PP PPP+
Sbjct: 415 TATAAFGARDSGEFRRAPAPPP------LPPAE-----PLAKEKPGTPPG-----PPPPD 458
Query: 623 ASRL----------SPPPEDSPMSPPPEESPMSP-PPEVSRLSPLPVVSR--------LS 663
+ + SP P DSP +P E SP P P S S + ++ + L
Sbjct: 459 TNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLR 518
Query: 664 PPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723
P ++ L E SP S +S+LSP S P P PP S LE+
Sbjct: 519 EPDSDTELQ--MEGSPIS--SSSSQLSPLAPFGTNSQPGFRGPT--PPSSRPSSTGLEDI 572
Query: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783
PLP+ + G L PRP P P P + L Q E L V
Sbjct: 573 SPTPLPDSDEDEELDLG--LGPRP-----PPEPGPP------DPAGLLSQTAEVALDLVG 619
Query: 784 EE-PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCL 842
+ P EG S + E+ +E +P+ C P + + L
Sbjct: 620 DRTPTSEKMDEGQQSSGEDMEI----SDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVL 675
Query: 843 SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSE 902
+P L P PPL P P PP +PG P P LP PPP P+ PA++
Sbjct: 676 AP---TLPLPPPPGFPPLPPPPPPPPPQPG-FPMPPPLPPPPPPPPPA------HPAVTV 725
Query: 903 PGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELE--YP 960
P PP PLP +P +PP P+ PPL P PP L P+ +++ +
Sbjct: 726 P--PP--PLP-------------APPGVPPPPILPPLPPF-----PPGLFPVMQVDMSHV 763
Query: 961 FGAKGDSDPES-PLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEP 1019
G + P S + +L ++ + C P PP + + + G +
Sbjct: 764 LGGQWGGMPMSFQMQTQVLSRLMT--GQGAC----PYPPFMAAAAAAASAG----LQFVN 813
Query: 1020 LPPQCSPLLQHSLVP---QNSPPSQCSPPALP 1048
LPP P + P Q+ PP P++P
Sbjct: 814 LPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVP 845
Score = 98.2 bits (243), Expect = 2e-19
Identities = 176/656 (26%), Positives = 223/656 (33%), Gaps = 101/656 (15%)
Query: 406 PKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEAS 465
PK G + A+PL E + E+ L+EE EE+ E+ +
Sbjct: 1014 PKGVGVRRRPARPLELDSGGEEDEKES-LSEEQESTEEEEEAEEEEEEEDDDDDDSDDRD 1072
Query: 466 RLSPPPEELPASPLPEALHLSRPLEE--SPLSPPPEESPLSPPPESSPFSPLEESPLSPP 523
E+ S E EE S ++ E + S ESS F ES S
Sbjct: 1073 ESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSS 1132
Query: 524 EESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL----------PTSPPPEASRLS 573
E+ A E E EES S PE+ P +P ++ +
Sbjct: 1133 EDEEEVVAREEEEEEEEEEMVA----EESMASAGPEDFEQDGEEAALAPGAPAVDSLGME 1188
Query: 574 PPPEESPMSPPPEESP--MSPPPEASRLFPPFEESPLSP--PPEESPLS--------PPP 621
+ + PEE P + PP P E P PPEE LS P P
Sbjct: 1189 EEVDIETEAVAPEERPSMLDEPP-----LPVGVEEPADSREPPEEPGLSQEGAMLLSPEP 1243
Query: 622 EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS 681
A + P SP P + + P P + + PLP+ L PP P SPPPE T
Sbjct: 1244 PAKEVEARPPLSPERAPEHDLEVEPEPPM--MLPLPLQPPLPPPRPPRPPSPPPEPETT- 1300
Query: 682 PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM--SLPLEESPLLPLPEEPQLCPRSE 739
+AS S PPE P ED P P + S E P P EP L S
Sbjct: 1301 ---DASHPSVPPE-----PLAEDHPPHTPGLCGSLAKSQSTETVPATP-GGEPPLSGGSS 1351
Query: 740 GPHLSPR--PEEPHLSPRPEEPHLS----PQAEEPHLS-----PQPEEPCLCAV-PEEPH 787
G LS P P P P P LS P+ S +P P L V P
Sbjct: 1352 GLSLSSPQVPGSPFSYPAPS-PSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTG 1410
Query: 788 LSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE-PCLSPQPEESHLSPQSEEPCLSPRP 846
+ GP SP E L P P+P P P + + P L P P
Sbjct: 1411 RRDERSGPLASPVLLETGL------PLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAP 1464
Query: 847 EESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEP 906
S PP+ +P +P P P L L P P LG L PG+P
Sbjct: 1465 LASC------PPPMKRKPGRPRRSP-----PSMLSLDGPLVRPPAGAALGRELLLLPGQP 1513
Query: 907 PLSPLPEE-------LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELE- 958
P L +G P+ P L P P PPP P+ P P EL+
Sbjct: 1514 QTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPV-----EPTKLPFKELDN 1568
Query: 959 ------YPFGAKG-DSDPESPLAAPILETPISPPPEANCTD--PEPVPPMILPPSP 1005
P G +G D E + P PP+ D P P + PP P
Sbjct: 1569 QWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624
Score = 97.4 bits (241), Expect = 3e-19
Identities = 126/434 (29%), Positives = 164/434 (37%), Gaps = 59/434 (13%)
Query: 367 PVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQL 426
P SR P EPG + A+ ++ +P V + P P E P V+
Sbjct: 1219 PADSREPPEEPG---LSQEGAMLLS--PEPPAKEVEARPPLSP-----ERAPEHDLEVEP 1268
Query: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLS 486
EP + PL + PL PP P SPPPE T +AS S PPE L P L
Sbjct: 1269 EPPMMLPLPLQPPLPPPRPPRPPSPPPEPETT----DASHPSVPPEPLAEDHPPHTPGLC 1324
Query: 487 RPLEESPLSPPPEESPLSPPPESSPFSPLEES----PLSPPEESPPSPALET---PLSPP 539
L +S + +P PP S S L S P SP PSP+L + P +P
Sbjct: 1325 GSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPG 1384
Query: 540 PEASPLSPPFEE--SPLSPPPEELPTSPPPEAS-RLSPPPEESPMSPPPEESPMSPPPEA 596
+ S +P F E PL P LPT E S L+ P P P P+ P
Sbjct: 1385 RDFS-FTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLAL 1443
Query: 597 SRLFPPFEESPLS-PPPEESPL-SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLS 654
+ +P PP +PL S PP R P SP S + P+ PP + L
Sbjct: 1444 PAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALG 1503
Query: 655 PLPVVSRLSPPPEESPLSPPPEESPT-----------SPPPEASRLSPPPEDSPTSPPPE 703
+ L P ++P+ P + T +PPP PP+ P PPP
Sbjct: 1504 RELL---LLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPL-----PPQPPPPPPPPP 1555
Query: 704 DSPASPPPEDSLMSLPLEESPLLP-----LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE 758
P P ++ P E P P + EE +S GP P P+
Sbjct: 1556 VEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRP--------PKKRH 1607
Query: 759 PHLSPQAEEPHLSP 772
L P A P LSP
Sbjct: 1608 EDLVPPAGSPELSP 1621
Score = 92.4 bits (228), Expect = 1e-17
Identities = 151/605 (24%), Positives = 201/605 (33%), Gaps = 96/605 (15%)
Query: 486 SRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPL 545
+RPLE E+ LS ES+ E ++ E + L
Sbjct: 1024 ARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTAL 1083
Query: 546 SPPFEESPLSPPPEELPT--SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603
S E+ EE + + EA+ S E S E SP S E +
Sbjct: 1084 SEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREE 1143
Query: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLS 663
EE EE E S S PED EE+ ++P P V L
Sbjct: 1144 EE-------EEEEEEMVAEESMASAGPED--FEQDGEEAALAPGA--------PAVDSLG 1186
Query: 664 PPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723
E E +P S L PP P + + PPE+ +S +E
Sbjct: 1187 MEEEVDI-----ETEAVAPEERPSMLDEPPLPVGVEEPAD---SREPPEEPGLS---QEG 1235
Query: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783
+L PE P + P R E L PE P + P +P L P P P + P
Sbjct: 1236 AMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPP-PRPPRPPSPP 1294
Query: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843
EP + + H S PE L + PH + S E +P E P
Sbjct: 1295 PEPETT---DASHPSVPPEPL---AEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSG 1348
Query: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEE-----LPLFPPPGEPSLSPL---- 894
S SP++ P S P G P P F P P L P+
Sbjct: 1349 GSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLP 1408
Query: 895 ----------LGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIIT 944
L P L E G P PLP LPL+ L Q P PLPP L P
Sbjct: 1409 TGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAV--LRAQARAPTPLPP-LLPAPL 1465
Query: 945 AAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPS 1004
A+ PP P K SP + L+ P+ PP E ++LP
Sbjct: 1466 ASCPP----------PMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGREL---LLLPGQ 1512
Query: 1005 PGSPVGPAS--------------------PILMEPLPPQCSPLLQHSLVP----QNSPPS 1040
P +PV P++ P+ +P PP P ++ + +P N PS
Sbjct: 1513 PQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPS 1572
Query: 1041 QCSPP 1045
+ PP
Sbjct: 1573 EAIPP 1577
Score = 83.2 bits (204), Expect = 7e-15
Identities = 103/362 (28%), Positives = 127/362 (35%), Gaps = 89/362 (24%)
Query: 381 PTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPL 440
P +EP A A G G P P A+PL K P P M L
Sbjct: 410 PPEEPTA--TAAFGARDSGEFRRAPAPPPLP---PAEPLAKEKPGTPPGPPPPDTNSMEL 464
Query: 441 --------LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRP---- 488
P P +SP +P E SP P L E L + L L P
Sbjct: 465 GGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDT 524
Query: 489 ---LEESPLSPPPEE-SPLSP-------------PPESSPFS---------PLEES---- 518
+E SP+S + SPL+P PP S P S PL +S
Sbjct: 525 ELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDE 584
Query: 519 -------PLSPPEESPPSPA------LETPLSPPPEASPLSPPFEESPLSP------PPE 559
P PPE PP PA E L + +P S +E S +
Sbjct: 585 ELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDD 644
Query: 560 ELPTSPPPEASRLSP---PPEESPMSPP---PEESPMSPPPEASRLFPPFEESPLSPPPE 613
E+P++P A P P + ++ P P+ PPP FPP P PPP+
Sbjct: 645 EMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPG----FPPLPPPPPPPPPQ 700
Query: 614 ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673
PPP L PPP P PP + PPP PLP + PPP PL P
Sbjct: 701 PGFPMPPP----LPPPP---PPPPPAHPAVTVPPP------PLPAPPGVPPPPILPPLPP 747
Query: 674 PP 675
P
Sbjct: 748 FP 749
Score = 82.0 bits (201), Expect = 1e-14
Identities = 129/477 (27%), Positives = 176/477 (36%), Gaps = 90/477 (18%)
Query: 685 EASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLS 744
EA+ S E S E SP+S E+ +++ EE EE ++
Sbjct: 1108 EATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEE-----EEEEMVA-------- 1154
Query: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQP-EE 803
EE S PE+ EE L+P + EE + +A P P +E
Sbjct: 1155 ---EESMASAGPED--FEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDE 1209
Query: 804 LHLSPQTEEPHLS-PVPEEPCLSPQ------PEESHLSPQSEEPCLSPRPEESHLSPELE 856
L EEP S PEEP LS + PE ++ P R E L E E
Sbjct: 1210 PPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPE 1269
Query: 857 KPPLSPRPEKPPEEPGQCPAPEELPLFP-------------------PPGEPSLSPLLGE 897
P + P P +PP P + P P P P PP P L L +
Sbjct: 1270 PPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAK 1329
Query: 898 PALSEP------GEPPLSPLPEELPLS-----------PSGEPSLSPQLMPPDP-LPPPL 939
+E GEPPLS L LS P+ PSLS +P P
Sbjct: 1330 SQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSF 1389
Query: 940 SPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPI-LETPISPPPEANCTDPEPVP- 997
+P + + P L P+ L P G + + PLA+P+ LET + P P P+P
Sbjct: 1390 TPTFSEPSGPLLLPVCPL--PTGRR--DERSGPLASPVLLETGLPLPLPL----PLPLPL 1441
Query: 998 --PMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPL 1055
P +L +P P P+L PL P+ + P+ SPPS L L P
Sbjct: 1442 ALPAVLRAQARAPT-PLPPLLPAPLASCPPPMKRKPGRPRRSPPSM-----LSLDGPLVR 1495
Query: 1056 SPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPAL 1112
P G +G EL + +P+ P PS P + + P+P P L
Sbjct: 1496 PPAGAALG----RELLLLP----GQPQTPVF-PSTHDPRTVTLDFRNAGIPAPPPPL 1543
Score = 78.6 bits (192), Expect = 2e-13
Identities = 107/389 (27%), Positives = 140/389 (35%), Gaps = 92/389 (23%)
Query: 442 PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS-------------------PLPEA 482
PPP ++ +P + + + + PPPEE P + PLP A
Sbjct: 382 PPPAQATPAPGFKSAFSPYQTPVAHFPPPPEE-PTATAAFGARDSGEFRRAPAPPPLPPA 440
Query: 483 LHLSRPLEESPLSPPPEES-----------PLSPPPESSPFSP-LEESPLSP--PEESPP 528
L++ +P PPP ++ SP P SP +P LE SP P P +S
Sbjct: 441 EPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLD 500
Query: 529 S------------------PALETPLSPPPEASPLSPPFEE-SPLSP------------- 556
S P +T L E SP+S + SPL+P
Sbjct: 501 SRIEMLLKEQRTKLLFLREPDSDTELQ--MEGSPISSSSSQLSPLAPFGTNSQPGFRGPT 558
Query: 557 PPEELPTSPPPEASRLSPPP-----EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611
PP P+S E +P P EE + P P PP+ + L E L
Sbjct: 559 PPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLV 618
Query: 612 PEESPLSPPPEASRLSPPPE----DSPMSPPPEESPMSPPPEVSRLSPLPVV--SRLSPP 665
+ +P S + + S + D M P S P P V V S L+P
Sbjct: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAP- 677
Query: 666 PEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL 725
PL PPP P PPP PPP+ PPP P PPP + P P
Sbjct: 678 --TLPLPPPPGFPPLPPPPP----PPPPQPGFPMPPPLPPPPPPPPP----AHPAVTVPP 727
Query: 726 LPLPEEPQLCPRSEGPHLSPRPEEPHLSP 754
PLP P + P P L P P P L P
Sbjct: 728 PPLPAPPGVPPPPILPPLPPFP--PGLFP 754
Score = 78.2 bits (191), Expect = 2e-13
Identities = 189/854 (22%), Positives = 271/854 (31%), Gaps = 151/854 (17%)
Query: 402 TSMQPKEPGPLQCEAKP--LGKAGVQLEPQLEAPLNEEMPL----LPPPEESPLSPPP-- 453
T+ QP GP ++P G + P ++ +EE+ L PPPE P P
Sbjct: 548 TNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLL 607
Query: 454 ------------EESPTSPPPEASRLSP------PPEELPASPLPEALHLSRPLEESP-- 493
+ +PTS + + S +E+P++P+ A +P+ +P
Sbjct: 608 SQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSA-DCPKPMVVTPGA 666
Query: 494 --LSPPPEESPLSPPPESSPFSPLEESPLSPPEES--PPSPALETPLSPPPEASPL---- 545
++ P +P P P F PL P PP + P P L P PPP A P
Sbjct: 667 AAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVP 726
Query: 546 SPPFEESPLSPPPEELPTSPP--PEASRLSPPPEESPMSPPPEESPMSPPPEA---SRL- 599
PP P PPP LP PP P + + PMS + SRL
Sbjct: 727 PPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLM 786
Query: 600 -------FPPFEESPLSP----------PPEESPLS----PPPEASRLSPPPEDSPMSPP 638
+PPF + + PP P S P P P+ P PP
Sbjct: 787 TGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPP 846
Query: 639 PEESPMSPPPEVSRLSP--LPVVSRLSPPPEESPLSPPPEESPTSPPPE---ASRLSPPP 693
P P P + + L V+ L + E E
Sbjct: 847 PGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKA 906
Query: 694 EDSPTSPPPEDSPASPPPEDSLMSLPLEE------------------SPLLPLPEEPQLC 735
+P P P+D + S LE + LP
Sbjct: 907 SLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLPSFK--V 964
Query: 736 PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP 795
R E P + ++ L P ++E + PC A + P+ G
Sbjct: 965 KRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRD-----PKGVGV 1019
Query: 796 HLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPEL 855
P L L EE + EE + + EE+ + E+ + +
Sbjct: 1020 RRRPA-RPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDD 1078
Query: 856 EKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPA---LSEPGEPPLSPLP 912
E LS EK + G E + + E + S E + S P S
Sbjct: 1079 EDTALSEASEK---DEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDE 1135
Query: 913 EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESP 972
EE+ E +++ + + +A P GE + P +P
Sbjct: 1136 EEVVAREEEEEEEEEEMVAEESM--------ASAGPEDFEQDGE-------EAALAPGAP 1180
Query: 973 LAAPI-LETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHS 1031
+ +E + EA PE P M+ P PVG P + P P L
Sbjct: 1181 AVDSLGMEEEVDIETEA--VAPEERPSML--DEPPLPVGVEEPA--DSREPPEEPGLSQE 1234
Query: 1032 LVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT 1091
SP PPA + PLSP + A H++E E PE P + P
Sbjct: 1235 GAMLLSP----EPPAKEVEARPPLSP--------ERAPEHDLEVE----PEPPMMLPLPL 1278
Query: 1092 SPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGS 1151
P P P+P P P D S PL ++ P TPG L GS
Sbjct: 1279 QPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPL-------AEDHPPHTPG-----LCGS 1326
Query: 1152 PVLLDPEELAPVTP 1165
E P TP
Sbjct: 1327 LAKSQSTETVPATP 1340
Score = 73.9 bits (180), Expect = 4e-12
Identities = 144/586 (24%), Positives = 204/586 (34%), Gaps = 93/586 (15%)
Query: 501 SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE 560
S ++P +PFS + + S ++P S TPL+P +P S S P P
Sbjct: 241 SSVTPNSGGTPFSQ-DTAYSSCRLDTPNSYGQGTPLTPRL-GTPFSQDSSYSSRQPTPSY 298
Query: 561 LPTSPPP-------EASRLSPPPEESPMSPPPEESP-MSPPPEASRLFPPFEESPLSPPP 612
L + P S+ + SP ++ A+ F + P
Sbjct: 299 LFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVG 358
Query: 613 EESPLSPPPEASRLSPPPEDSPM---SPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEES 669
S PP ++ P+DS +PPP ++ +P + S SP PPP E
Sbjct: 359 GTGGSSGPPFKAQ----PQDSATFAHTPPPAQATPAPGFK-SAFSPYQTPVAHFPPPPEE 413
Query: 670 PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP--PEDSLMSLPLEESPLLP 727
P + + S E R PP P P ++ P +PP P S+ L P
Sbjct: 414 PTATAAFGARDSG--EFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFG 471
Query: 728 LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPH 787
EP C P L P P E+PH S + L + L +
Sbjct: 472 WSPEP--CDSPGTPTLESSPAGP------EKPHDSLDSRIEMLLKEQRTKLLFLREPDSD 523
Query: 788 LSPQAEGPHLSPQPEELH-LSP---QTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843
Q EG +S +L L+P ++ P P S +P + L E+ +
Sbjct: 524 TELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPP----SSRPSSTGL----EDISPT 575
Query: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP 903
P P+ S E E+ L P +PP EPG PP L E AL
Sbjct: 576 PLPD----SDEDEELDLGLGP-RPPPEPG------------PPDPAGLLSQTAEVALDLV 618
Query: 904 GE-PPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFG 962
G+ P S +E S + +S MP P+ P P A +
Sbjct: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAA---------- 668
Query: 963 AKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPI-----LM 1017
+AAP + P P P P P P + PP P P P P+
Sbjct: 669 ----------VAAPSVLAPTLPLP------PPPGFPPLPPPPPPPPPQPGFPMPPPLPPP 712
Query: 1018 EPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSP--LSPIGKV 1061
P PP P + P +PP PP LP P P L P+ +V
Sbjct: 713 PPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQV 758
Score = 69.3 bits (168), Expect = 1e-10
Identities = 113/450 (25%), Positives = 144/450 (32%), Gaps = 40/450 (8%)
Query: 2118 PAAAPTIFIGSPTTPAGLSTSADGFLKP--PAGSVPG-----PDSPGELFLKLPPQVPAQ 2170
P P++ + P P G+ AD P P S G P+ P + PP P +
Sbjct: 1200 PEERPSM-LDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER 1258
Query: 2171 VPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTP 2230
P D + P P+ P PP PP P +P P +S P P
Sbjct: 1259 APEHD-LEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHP 1317
Query: 2231 PGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKE 2290
P TP S P+ P S G G S P + PF + +
Sbjct: 1318 PHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSG 1377
Query: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ 2350
L + P F +P+ G L L V P R + P + + L
Sbjct: 1378 GLPRT------PGRDFSFTPTFSEPSGPLLL---PVCPLPTGRRDERSGPLASPVLLETG 1428
Query: 2351 EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ---PPPPESCCALPPRSLPS-- 2405
P P P P + P + R + P PPL P P PPP + P RS PS
Sbjct: 1429 LPLPLPLPLPLPLALPAVLRAQARA-PTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSML 1487
Query: 2406 ---DPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDP 2462
P R PA + + L P F PS PR + D R P P
Sbjct: 1488 SLDGPLVRPPAG--AALGRELLLLPGQPQTPVF-PSTHDPRTVTLD--FRNAGIPAPPPP 1542
Query: 2463 FAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP 2522
P PP P PP K L L A+P GP G +
Sbjct: 1543 LPPQPPPPPPPPPVEPTK---LPFKELDNQWPSEAIPPGPRGR-----DEVTEEYMELAK 1594
Query: 2523 GTGAFVGTPSPMRFTFPQAVGEPSLKPPVP 2552
G + P G P L PP P
Sbjct: 1595 SRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624
Score = 68.9 bits (167), Expect = 1e-10
Identities = 116/457 (25%), Positives = 148/457 (32%), Gaps = 75/457 (16%)
Query: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALH-LSRPLEESPLSPPPEESPLSPPPE 508
S PP ++ + PP + PA A P+ P PPPEE +
Sbjct: 364 SGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFP--PPPEEPTATAAFG 421
Query: 509 SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPE 568
+ +P P P P A PL+ +P PPP P
Sbjct: 422 ARDSGEFRRAPAPP---------------PLPPAEPLAKEKPGTPPGPPP------PDTN 460
Query: 569 ASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP 628
+ L P SP P +SP +P E+S P L E + L
Sbjct: 461 SMELGGRPTFG-WSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLRE 519
Query: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
P D+ + E SP+S S+LSPL S P P PP P+S E
Sbjct: 520 PDSDTELQ--MEGSPIS--SSSSQLSPLAPFGTNSQPGFRGP--TPPSSRPSSTGLEDIS 573
Query: 689 LSPPPEDSPTS---------PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSE 739
+P P+ PPPE P P L+S E + L P E
Sbjct: 574 PTPLPDSDEDEELDLGLGPRPPPEPGPPDPA---GLLSQTAEVALDLVGDRTPTSEKMDE 630
Query: 740 GPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSP 799
G S E P P S +P + P AV L+P L P
Sbjct: 631 GQQSSGEDMEISDDEMPSAPITSADCPKPMV----VTPGAAAVAAPSVLAPTLP---LPP 683
Query: 800 QPEELHLSPQTEEPHLSP-VPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP 858
P L P P P P P L P P P P +H + + P
Sbjct: 684 PPGFPPLPPPPPPPPPQPGFPMPPPLPPPP---------------PPPPPAHPAVTVPPP 728
Query: 859 PLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895
PL P PG P P PL PP P L P++
Sbjct: 729 PL-------PAPPGVPPPPILPPL--PPFPPGLFPVM 756
Score = 62.8 bits (151), Expect = 9e-09
Identities = 136/540 (25%), Positives = 182/540 (33%), Gaps = 131/540 (24%)
Query: 2119 AAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFG 2178
A A F GS P G G PP + P + F PP PAQ F
Sbjct: 340 AGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSAT---FAHTPP--PAQATPAPGFK 394
Query: 2179 LAPA--------YPLEPRFPTAPPTYPPYPSPT--GAPAQPPMLGASSRPGAGQPGEFHT 2228
A + +P P PTA + S APA PP+ A +PG
Sbjct: 395 SAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPL-AKEKPG---- 449
Query: 2229 TPPGTPRHQPST------------PDPFLKPRCPSLDNL-AVPESPGVGGGKASEPLLSP 2275
TPPG P ++ P+P P P+L++ A PE P E LL
Sbjct: 450 TPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKE 509
Query: 2276 PPFG-------ESRKALEVKKEELGASSPSYGP---------PNLGFVDSPSSGTHLGGL 2319
+S L+++ + +SS P P PSS GL
Sbjct: 510 QRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGL 569
Query: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPP----PAQALAPSPPSHPDIFRPGSYT 2375
E D+ PL P + + E GLG RP P PA L+ + D+ + T
Sbjct: 570 E----DISPTPL-PDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPT 624
Query: 2376 -------------------DPYAQPPLT----PRPQPPPPESCCALPPRSL-PSDPFSRV 2411
D P+T P+P P + P L P+ P
Sbjct: 625 SEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPP 684
Query: 2412 PASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPR 2471
P P PL P P P P P F P P PP P P + PP
Sbjct: 685 PGFP--------PLPPPPP------PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL 730
Query: 2472 PQPPEV----------AFKAG-------SLAHTSLGA-GGFPAALPAGPAGELHAKVPSG 2513
P PP V F G ++H G GG P + ++ +++ +G
Sbjct: 731 PAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQM--QTQVLSRLMTG 788
Query: 2514 QP----PNFVRSPGTGA-----FVGTPSPMRFTFPQAVGEPSLK---PPVPQ--PGLPPP 2559
Q P F+ + A FV P P R F + P PP+P+ P +PPP
Sbjct: 789 QGACPYPPFMAAAAAAASAGLQFVNLP-PYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPP 847
Score = 61.2 bits (147), Expect = 3e-08
Identities = 120/463 (25%), Positives = 165/463 (35%), Gaps = 74/463 (15%)
Query: 2245 LKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNL 2304
L P P++D+L + E + +A P P E L V EE S P L
Sbjct: 1175 LAPGAPAVDSLGMEEEVDIET-EAVAPEERPSMLDEP--PLPVGVEEPADSREPPEEPGL 1231
Query: 2305 GFVDSPSSGTHLGGLELKTPDV-FKAPLTPRAS-----QVEPQSPGLGLRPQEPPPAQAL 2358
G L E +V + PL+P + +VEP+ P + P +PP
Sbjct: 1232 S-----QEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPR 1286
Query: 2359 APSPPSHPDIFRPGSYTDPYAQPPLTPRP----QPPPPESCCALPPRSLPSDPFSRVPAS 2414
P PPS P P T + P + P P PP C +S ++ VPA+
Sbjct: 1287 PPRPPSPP----PEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTE---TVPAT 1339
Query: 2415 PQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS----RPPSR-----PQSRDPFAP 2465
P + + LS+ SP + SP S R P R P +P P
Sbjct: 1340 PGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGP 1399
Query: 2466 LHKPPRPQPP-EVAFKAGSLAHTSLGAGGFPAALP-------AGPAG-ELHAKVPSGQPP 2516
L P P P ++G LA L G P LP A PA A+ P+ PP
Sbjct: 1400 LLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPP 1459
Query: 2517 NFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPP----VPQPGLPPPHGINSHFGPGPTL 2572
+ +P P PM+ + G P PP + P + PP G + G L
Sbjct: 1460 -LLPAP----LASCPPPMK----RKPGRPRRSPPSMLSLDGPLVRPPAG--AALGRELLL 1508
Query: 2573 --GKPQSTNY------TVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGS 2624
G+PQ+ + T +F +G P P L P PP PPP
Sbjct: 1509 LPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPP--------LPPQPPPPPPPPPVEPTK 1560
Query: 2625 LPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDP 2667
LP+ S P + D T LA + P + P
Sbjct: 1561 LPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPP 1603
Score = 61.2 bits (147), Expect = 3e-08
Identities = 77/290 (26%), Positives = 96/290 (33%), Gaps = 41/290 (14%)
Query: 354 GGQTIRSVAEQHTPVCSRFSPPEP------GDTP-TDEPDALYVACQGQPKGGHVTSMQP 406
GG + S++ P S FS P P G P T D + +P G + + P
Sbjct: 1348 GGSSGLSLSSPQVPG-SPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCP 1406
Query: 407 KEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPL---LPPPEESPLSPPPEESPTSPPPE 463
G + PL V LE L PL +PL LP + P P P P
Sbjct: 1407 LPTGRRDERSGPLASP-VLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPL 1465
Query: 464 ASRLSPPPEELPASPL---PEALHLSRPLEESP----------LSPPPEESPLSPPPESS 510
AS PP + P P P L L PL P L P ++P+ P
Sbjct: 1466 AS-CPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDP 1524
Query: 511 PFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEAS 570
L+ P PP P P PPP P PF+E P E +P P
Sbjct: 1525 RTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDE 1584
Query: 571 ---------------RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605
R P + PP +SPP R FEE
Sbjct: 1585 VTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEE 1634
Score = 60.5 bits (145), Expect = 5e-08
Identities = 105/402 (26%), Positives = 136/402 (33%), Gaps = 100/402 (24%)
Query: 792 AEGPHLSPQPEELHLSPQTEEP-HLSPVPE-EPCLSP-QPEESHLSPQSEEPCLSPR--- 845
+ GP QP++ T P +P P + SP Q +H P EEP +
Sbjct: 363 SSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGA 422
Query: 846 PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905
+ PPL P E+PG P P PPP S+ L G P E
Sbjct: 423 RDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGP------PPPDTNSME-LGGRPTFGWSPE 475
Query: 906 PPLSPLPEELPLSPSG------------EPSLSPQ------LMPPDP---LPPPLSPIIT 944
P SP L SP+G E L Q L PD L SPI +
Sbjct: 476 PCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISS 535
Query: 945 AAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPS 1004
+++ LSPL PFG P P P + T E + P LP S
Sbjct: 536 SSSQ--LSPLA----PFGTNSQ---------PGFRGPTPPSSRPSSTGLEDISPTPLPDS 580
Query: 1005 PGSP-----VGPASPILMEPLPPQCSPLLQHS------LVPQNSPPSQCSPPALPLSVPS 1053
+GP P EP PP + LL + LV +P S+ S
Sbjct: 581 DEDEELDLGLGPRPP--PEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSS--- 635
Query: 1054 PLSPIGKVVGVSDEAELHEMETEKVSEPECP---ALEPSA-----------TSPLPSPMG 1099
G+ + +SD+ EM + ++ +CP + P A T PLP P G
Sbjct: 636 -----GEDMEISDD----EMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPG 686
Query: 1100 DLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTP 1141
P P P P P G P P P P
Sbjct: 687 FPPLPPPPPPP------------PPQPGFPMPPPLPPPPPPP 716
Score = 60.1 bits (144), Expect = 6e-08
Identities = 122/504 (24%), Positives = 180/504 (35%), Gaps = 133/504 (26%)
Query: 3957 QQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQ--QQQQQQVALGPGMPA----------- 4003
+ +++ + ++++++++ + +S P+ +Q ++ AL PG PA
Sbjct: 1133 EDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVD 1192
Query: 4004 ---KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMAT 4060
+ + P L L G E+ PA S E E P Q G + + +PE A
Sbjct: 1193 IETEAVAPEERPSMLDEPPLPVGVEE----PADSREPPEEPGLSQEGAMLL--SPEPPAK 1246
Query: 4061 EPGEVKPSLSGD---SQLLLVQPQPQPQPSSLQLQPPL---------------------- 4095
E E +P LS + L V+P+P P L LQPPL
Sbjct: 1247 EV-EARPPLSPERAPEHDLEVEPEP-PMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASH 1304
Query: 4096 -RLPGQQQQQVSLLHTAG-----------------GGSHGQLGSGSSSEASSVPHL---- 4133
+P + + HT G G L GSS + S P +
Sbjct: 1305 PSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSP 1364
Query: 4134 ----LAQPSVSLGDQPG------SMTQNLLGPQQPMLERPMQNNTGPQPPKPGPV----- 4178
PS+S G P S T P P+L TG + + GP+
Sbjct: 1365 FSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVL 1424
Query: 4179 LQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVR 4238
L++G LP +P L A L+ L L P + ++ + R
Sbjct: 1425 LETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRP----R 1480
Query: 4239 QTPP--YQEPGTQTSPLQG--------LLGCQPQLGGFPG---PQTGPLQELGAGPRPQG 4285
++PP G P G LL QPQ FP P+T L AG
Sbjct: 1481 RSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAG----- 1535
Query: 4286 PPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLP--SPSSQLPTEAQLPPTHPG- 4342
+PAPP P+ P PPP P P P++LP +Q P+EA +PP G
Sbjct: 1536 ---IPAPPP---------PLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEA-IPPGPRGR 1582
Query: 4343 ---------TPKPQGPTLEPPPGR 4357
K +GP PP R
Sbjct: 1583 DEVTEEYMELAKSRGPWRRPPKKR 1606
Score = 57.8 bits (138), Expect = 3e-07
Identities = 85/332 (25%), Positives = 110/332 (33%), Gaps = 39/332 (11%)
Query: 361 VAEQHTP----VCSRFSPPEPGDT----PTDEPDALYVACQGQPKGGHVTSMQ-PKEPGP 411
+AE H P +C + + +T P EP G G ++S Q P P
Sbjct: 1312 LAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPL-----SGGSSGLSLSSPQVPGSPFS 1366
Query: 412 LQCEAKPLGKAGVQLEPQLEAPLNEEM-----PLLPPPEESPLSPPPEES-PTSPPPEAS 465
+ L G+ P + PLL P P E S P + P
Sbjct: 1367 YPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLE 1426
Query: 466 RLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE 525
P P LP PLP AL + +P P PL P P +S P++ P P
Sbjct: 1427 TGLPLPLPLPL-PLPLALPAVLRAQARAPTPLP---PLLPAPLASCPPPMKRKPGRPRRS 1482
Query: 526 SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPP 585
P +L+ PL PP + L P P P++ P L P PPP
Sbjct: 1483 PPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPP 1542
Query: 586 EESPMSPPPEASRLFP---PFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642
PPP + P PF+E P E P P R + M
Sbjct: 1543 LPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGP-----RGRDEVTEEYMELAKSRG 1597
Query: 643 PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
P PP+ L PP LSPP
Sbjct: 1598 PWRRPPKKRH-------EDLVPPAGSPELSPP 1622
Score = 55.1 bits (131), Expect = 2e-06
Identities = 89/341 (26%), Positives = 122/341 (35%), Gaps = 67/341 (19%)
Query: 940 SPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM 999
SP +TA A + G + PFGA G + S P P+ + T PP
Sbjct: 333 SPAVTAVAGATAAFRGSSDLPFGAVGGTGGSS-------GPPFKAQPQDSATFAHTPPPA 385
Query: 1000 ILPPSPG--SPVGP-ASPILMEPLPPQCSPLLQHSLVPQNS------PPSQCSPPALPLS 1050
P+PG S P +P+ P PP+ P + ++S P PPA PL+
Sbjct: 386 QATPAPGFKSAFSPYQTPVAHFPPPPE-EPTATAAFGARDSGEFRRAPAPPPLPPAEPLA 444
Query: 1051 VPSPLSPIGKVVGVSDEAELHEMET-----EKVSEPECPALEPSATSPLPSPMGDLSCPA 1105
P +P G ++ EL T E P P LE S P
Sbjct: 445 KEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGP------------ 492
Query: 1106 PSPAPALDDFSG--LGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPV 1163
P +LD L E L + P S E +++GSP+ +L+P+
Sbjct: 493 EKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTE---------LQMEGSPISSSSSQLSPL 543
Query: 1164 TPMEVYPECKQTAGQGSPCEEQEEPRA----PVAPTPPTLIKSDIVNEISNLSQGDASAS 1219
P G P P + ++PTP L SD E+ +L G
Sbjct: 544 APFGT----NSQPGFRGPTPPSSRPSSTGLEDISPTP--LPDSDEDEEL-DLGLG----- 591
Query: 1220 FPGSEPLLGSPDPEGGGSLSME-----LGVSTDVSPARDEG 1255
P P G PDP G S + E +G T S DEG
Sbjct: 592 -PRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEG 631
Score = 50.1 bits (118), Expect = 6e-05
Identities = 144/593 (24%), Positives = 191/593 (32%), Gaps = 129/593 (21%)
Query: 2384 TPRPQPPPPESCCALPPRSL-PSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTP 2442
TP Q SC P S P + +P SQ SS S P P + F P
Sbjct: 250 TPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTP--SYLFSQDPAVT 307
Query: 2443 RFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGP 2502
F++ S+ R +H P V AG+ A G+ P G
Sbjct: 308 -FKARRHESKFTDAYNRRHEHHYVHNSPA-----VTAVAGATA-AFRGSSDLPFGAVGGT 360
Query: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI 2562
G S PP + + F TP P + T A G S P P
Sbjct: 361 GG-------SSGPPFKAQPQDSATFAHTPPPAQAT--PAPGFKSAFSPYQTPV------- 404
Query: 2563 NSHFGPGPTLGKPQSTNYTVATGNFH--PSGSPLGPSSGSTGESYGLSPLRPPSVLPPPA 2620
+HF P P + +G F P+ PL P+ E G P PP
Sbjct: 405 -AHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPP-------GPPP 456
Query: 2621 PDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQ 2680
PD + L G G SP E + PGT S G + P S S+ E+ +
Sbjct: 457 PDTNSMEL--GGRPTFG-WSP-EPCDSPGTPTLESSPA----GPEKPHDSLDSRIEMLLK 508
Query: 2681 RQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFA 2740
QR +L L +R+ L+ E ++++ + P +G S P F RG TP +
Sbjct: 509 EQRTKL--LFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTN-SQPGF----RGPTPPS 561
Query: 2741 GTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLS-----RPPPPATPSSMDVNSRQLVGGS 2795
+ L + P+ L P S D+ L RPPP P
Sbjct: 562 SRPSSTGLEDISPTPL------PDS-DEDEELDLGLGPRPPPEPGP-------------- 600
Query: 2796 QAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGS--- 2852
P P L Q A A + + R P++ + G+Q+ G
Sbjct: 601 -------PDPAGL----------LSQTAEVALDL---VGDRTPTSEKMDEGQQSSGEDME 640
Query: 2853 ------PLAGI-STRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPR 2905
P A I S P P PG A A L + PG P P PP P+
Sbjct: 641 ISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQ 700
Query: 2906 FYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLP 2958
G P P PP P HP P LP
Sbjct: 701 ---------------------PGFP-MPPPLPPPPPPPPPAHPAVTVPPPPLP 731
Score = 47.0 bits (110), Expect = 5e-04
Identities = 105/445 (23%), Positives = 147/445 (33%), Gaps = 96/445 (21%)
Query: 4567 PAITANFSLFAPFGSGCPVNGQSQLR-GAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSS 4625
PA+TA A F G S L GA G +GP + +Q ++ P P +
Sbjct: 334 PAVTAVAGATAAF------RGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQA 387
Query: 4626 LPPTPPPSVQQKMVNGVTPSEELGEHPKD-----AASARDSERALR-------DTSEVKS 4673
TP P + TP P++ A ARDS R +E +
Sbjct: 388 ---TPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLA 444
Query: 4674 LDLLAALPTPPHNQTEDVRME-------SDEDSDSPDSIVPASSP--------------E 4712
+ P PP T + + S E DSP + SSP E
Sbjct: 445 KEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIE 504
Query: 4713 SILGEEAPRFPHLGSGRWEQE-----------DRALSPVIPL----IPRASIPVFPDTKP 4757
+L E+ + L + E LSP+ P P P P ++P
Sbjct: 505 MLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRP 564
Query: 4758 YGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEV 4817
+ GLE P+ S+ L + A LLS + ++
Sbjct: 565 -SSTGLEDISPTPLPD------SDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDL 617
Query: 4818 LFPESPARAGTEPKKGEAEGPGGKEKGLEG----KSPDTGPDWLKQFDAVLPGYTLKSQL 4873
+ +P T K E + G++ + +P T D K V PG + +
Sbjct: 618 VGDRTP----TSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPM-VVTPG---AAAV 669
Query: 4874 DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEE------PSPPPSPLAPSPAS 4927
S+L P P PP L PPP P PPP P P P
Sbjct: 670 AAPSVLAPTLPLPPPP------------GFPPLPPPPPPPPPQPGFPMPPPLP-PPPPPP 716
Query: 4928 PPTEPLVELPTEPLAEPPVPSPLPL 4952
PP P V +P PL PP P P+
Sbjct: 717 PPAHPAVTVPPPPLPAPPGVPPPPI 741
Score = 45.8 bits (107), Expect = 0.001
Identities = 102/428 (23%), Positives = 146/428 (34%), Gaps = 80/428 (18%)
Query: 4619 PPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLA 4678
PP PP P P P V P +HP S ++ +S + +
Sbjct: 1284 PPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGS------LAKSQSTETVP 1337
Query: 4679 ALP---TPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDR 4735
A P P + + + S + SP S PA SP S+ PR P GR D
Sbjct: 1338 ATPGGEPPLSGGSSGLSLSSPQVPGSPFSY-PAPSP-SLSSGGLPRTP----GR----DF 1387
Query: 4736 ALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKN 4795
+ +P ++P G L LPV G+ E S L
Sbjct: 1388 SFTPTF-------------SEPSGPL------LLPVCPLPTGRRDERSGPLA-------- 1420
Query: 4796 LNGVMVAVAELLSMKIPNSYEVLFP---ESPARAGTE-----PKKGEAEGPGGKEKGLEG 4847
+ V++ L + +P + P + ARA T P + P K K G
Sbjct: 1421 -SPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRK--PG 1477
Query: 4848 KSPDTGPDWLKQFDAVL----PGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDV 4903
+ P P + D L G L +L +L Q P + T + N +
Sbjct: 1478 R-PRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGI 1536
Query: 4904 RQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSP----------LPLA 4953
APPP P PP P P P P P EL + +E P P + LA
Sbjct: 1537 ---PAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELA 1593
Query: 4954 SSPESARPKPRAR-----PPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQEDERE 5008
S R P+ R PP + PP+ ++ + +L I G +ED R
Sbjct: 1594 KSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRF 1653
Query: 5009 VAEFMEQL 5016
+ E+L
Sbjct: 1654 LCVTYERL 1661
Score = 43.9 bits (102), Expect = 0.004
Identities = 72/303 (23%), Positives = 105/303 (34%), Gaps = 46/303 (15%)
Query: 4054 TPESMATEPGEVKPSLSGDSQLLLVQPQPQPQ-------PSSLQLQPPLRLPGQQQQQVS 4106
TP ++ G KP S DS++ ++ + + + S +LQ Q+S
Sbjct: 482 TPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLS 541
Query: 4107 LLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQN 4166
L A G++ Q G + SS P +S P S + +
Sbjct: 542 PL--APFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDE-----------DEELDL 588
Query: 4167 NTGPQPP-KPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQAL 4225
GP+PP +PGP G++ ++ L G + P + QQ + +
Sbjct: 589 GLGPRPPPEPGPP-------DPAGLLSQTAEVALDLVG--DRTPTSEKMDEGQQSSGEDM 639
Query: 4226 LMQRQLQQSQAVRQT----PPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGP 4281
+ S + P PG +L P L P P G P
Sbjct: 640 EISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLA--PTLPLPPPP--------GFPP 689
Query: 4282 RPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHP 4341
P PP P PG P L P P PPP+ P P LP+P +P LPP P
Sbjct: 690 LPPPPPPPPPQPG-FPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG-VPPPPILPPLPP 747
Query: 4342 GTP 4344
P
Sbjct: 748 FPP 750
Score = 41.6 bits (96), Expect = 0.022
Identities = 28/74 (37%), Positives = 29/74 (39%), Gaps = 11/74 (14%)
Query: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346
P LP PP P P P PPP P +P P P P P PP HP P
Sbjct: 677 PTLPLPP------PPGFPPLPPPPPPPPPQPGFPMPPPLP----PPPPPPPPAHPAVTVP 726
Query: 4347 QGPTLEPPPGRVSP 4360
P L PPG P
Sbjct: 727 P-PPLPAPPGVPPP 739
Score = 40.8 bits (94), Expect = 0.038
Identities = 49/178 (27%), Positives = 59/178 (33%), Gaps = 37/178 (20%)
Query: 2104 LRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKL 2163
L +PP PG PPP P G P P PA +VP P P +
Sbjct: 679 LPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPP 738
Query: 2164 PPQVPAQVPSQDPFGLAPAYPLE-----------------------PRFPTAPPT--YPP 2198
PP +P P P GL P ++ R T YPP
Sbjct: 739 PPILPPLPPF--PPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPP 796
Query: 2199 YPSPTGAPAQ--------PPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPR 2248
+ + A A PP G S +G PG PP P+ PS P P PR
Sbjct: 797 FMAAAAAAASAGLQFVNLPPYRGPFSLSNSG-PGRGQHWPP-LPKFDPSVPPPGYMPR 852
Score = 40.0 bits (92), Expect = 0.064
Identities = 86/327 (26%), Positives = 112/327 (34%), Gaps = 81/327 (24%)
Query: 2702 QEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPP-------- 2753
Q ET A G PP S G+ S + Q+ + S GLP
Sbjct: 1331 QSTETVPATPGGE-PPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSF 1389
Query: 2754 ----SKLSGPILGPGS-FPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSL 2808
S+ SGP+L P P+ R R P A+P ++ P P L
Sbjct: 1390 TPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLP------------LPLPLPL 1437
Query: 2809 PLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPV 2868
PL + + Q A A T + + A S P P ++ G P + L G V
Sbjct: 1438 PLPLALPAVLRAQ-ARAPTPLPPLLPAPLASCPPPM--KRKPGRPRRSPPSMLSLDGPLV 1494
Query: 2869 PGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSG 2928
PAG A LG PGQ PQ P F P + DP + + R +
Sbjct: 1495 RPPAGAA------------LGRELLLLPGQ--PQTPVF-PSTHDPRTVTLD-FRNAGIPA 1538
Query: 2929 ----LPPQKPSAPPAP----------ELNN-----SLHPTPHTKGPTLPTGLELV----- 2964
LPPQ P PP P EL+N ++ P P + +EL
Sbjct: 1539 PPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGP 1598
Query: 2965 -NRPP-----------SSTELGRPNPL 2979
RPP S EL P PL
Sbjct: 1599 WRRPPKKRHEDLVPPAGSPELSPPQPL 1625
Score = 39.7 bits (91), Expect = 0.084
Identities = 65/271 (23%), Positives = 96/271 (35%), Gaps = 32/271 (11%)
Query: 3091 PGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRH-PSPCQFTIATPKVEPAPAANS 3149
P P P PPP + ++ SV PE P E+ H P C + E PA
Sbjct: 1285 PRPPRPPS-PPPEPETTDASHPSVPPE--PLAEDHPPHTPGLCGSLAKSQSTETVPATPG 1341
Query: 3150 LGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSL 3209
L G S + ++ PFS + +S G P S P G L
Sbjct: 1342 GEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLL 1401
Query: 3210 LEKFELESGALTLPGGPAASGDELDKMESSL-----VASELPLLIEDLLEHEKKELQKKQ 3264
L L +G GP AS L E+ L + LPL + +L + +
Sbjct: 1402 LPVCPLPTGRRDERSGPLASPVLL---ETGLPLPLPLPLPLPLALPAVLRAQARAPTPLP 1458
Query: 3265 QL----SAQLQPAQQQ---QQQQQQHSLLSAPGP-----------AQAMSLPHEGSSPSL 3306
L A P ++ + ++ S+LS GP + + LP + +P
Sbjct: 1459 PLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVF 1518
Query: 3307 AGSQ--QQLSLGLAGARQPGLPQPLMPTQPP 3335
+ + ++L A P P PL P PP
Sbjct: 1519 PSTHDPRTVTLDFRNAGIPAPPPPLPPQPPP 1549
Score = 39.3 bits (90), Expect = 0.11
Identities = 63/261 (24%), Positives = 89/261 (34%), Gaps = 57/261 (21%)
Query: 4511 DAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAIT 4570
D+ L P +K D L S + L KE + EL + + +
Sbjct: 478 DSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSS 537
Query: 4571 ANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLP--- 4627
+ S APFG+ N Q RG PTPPSS P
Sbjct: 538 SQLSPLAPFGT----NSQPGFRG--------------------------PTPPSSRPSST 567
Query: 4628 ------PTPPPSVQQKMVNGVTPSEEL----GEHPKDAASARDSERALRDTSEVKSLDLL 4677
PTP P + EEL G P D L T+EV +LDL+
Sbjct: 568 GLEDISPTPLPDSDE--------DEELDLGLGPRPPPEPGPPDPAGLLSQTAEV-ALDLV 618
Query: 4678 AALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWE-QEDRA 4736
TP + ++ + S ED + D +P++ I + P+ + G
Sbjct: 619 GDR-TPTSEKMDEGQQSSGEDMEISDDEMPSAP---ITSADCPKPMVVTPGAAAVAAPSV 674
Query: 4737 LSPVIPLIPRASIPVFPDTKP 4757
L+P +PL P P P P
Sbjct: 675 LAPTLPLPPPPGFPPLPPPPP 695
Score = 38.9 bits (89), Expect = 0.14
Identities = 25/68 (36%), Positives = 26/68 (38%), Gaps = 6/68 (8%)
Query: 4289 LPAPPGALSTGPVLGPVHPTPPPS--SPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346
LP PPG P L P P PPP P P P P P P PP P P
Sbjct: 681 LPPPPGF----PPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGV 736
Query: 4347 QGPTLEPP 4354
P + PP
Sbjct: 737 PPPPILPP 744
Score = 38.9 bits (89), Expect = 0.14
Identities = 43/170 (25%), Positives = 61/170 (35%), Gaps = 25/170 (14%)
Query: 4812 PNSYEVLFPESPARAGTEP---KKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYT 4868
P + E P G E + E PG ++G SP+ ++ + P
Sbjct: 1200 PEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERA 1259
Query: 4869 LKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP--PEEPSPPPSPLAPSPA 4926
+ L++ PEPP + L ++ PP P PSPPP P +
Sbjct: 1260 PEHDLEV---------EPEPPM-------MLPLPLQPPLPPPRPPRPPSPPPEPETTDAS 1303
Query: 4927 SP--PTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDS 4974
P P EPL E P P + L + S E+ P PP G S
Sbjct: 1304 HPSVPPEPLAE--DHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSS 1351
Score = 35.8 bits (81), Expect = 1.2
Identities = 82/368 (22%), Positives = 130/368 (35%), Gaps = 44/368 (11%)
Query: 4627 PPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTS-EVKSLDL----LAALP 4681
PP S QK + T +E +D S R+ +R + DT E+ D + P
Sbjct: 969 PPDTTSSGDQKRLRPSTSVDE-----EDEESERERDRDMADTPCELAKRDPKGVGVRRRP 1023
Query: 4682 TPP----HNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRAL 4737
P ED + E+ +S + A E ++ + ED AL
Sbjct: 1024 ARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTAL 1083
Query: 4738 SPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLN 4797
S AS D+ + + ++ E + SE S +++++
Sbjct: 1084 S-------EASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEE 1136
Query: 4798 GVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAE----GPGGKEKGLEGKSPDTG 4853
V+ E + E++ ES A AG E + + E PG G +
Sbjct: 1137 EVVAREEE----EEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVD 1192
Query: 4854 PDWLKQFDAVLPGYTLKSQLDILSL---LKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP 4910
+ +AV P S LD L +++ + + EPP + + + L LS P
Sbjct: 1193 IET----EAVAPEER-PSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAML----LSPEP 1243
Query: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP-PVPSPLPLASSPESARPKPRARPPE 4969
P + PL+P A P L P P+ P P+ PLP P P P +
Sbjct: 1244 PAKEVEARPPLSPERA--PEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTD 1301
Query: 4970 EGEDSRPP 4977
S PP
Sbjct: 1302 ASHPSVPP 1309
Score = 35.0 bits (79), Expect = 2.1
Identities = 30/103 (29%), Positives = 39/103 (37%), Gaps = 8/103 (7%)
Query: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLA-PSPASPPTEPLVELPTEPLA 4942
P PE PT + + + R+ APPP PP PLA P +PP P + + L
Sbjct: 409 PPPEEPTATAAFGARDSGEFRRAPAPPP---LPPAEPLAKEKPGTPPGPPPPDTNSMELG 465
Query: 4943 EPPV----PSPLPLASSPESARPKPRARPPEEGEDSRPPRLKK 4981
P P P +P P + DSR L K
Sbjct: 466 GRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLK 508
Score = 33.5 bits (75), Expect = 6.0
Identities = 41/156 (26%), Positives = 49/156 (31%), Gaps = 40/156 (25%)
Query: 4266 FPGPQTGPLQELGAGPRPQGPP-------------------RLPAPPGALSTGPVLGPVH 4306
F G P +G GPP PAP + P PV
Sbjct: 346 FRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVA 405
Query: 4307 PTPPPSSPQEPKRPSQLPSPSS----QLPTEAQLPPTHP-GTPKPQGPTLEPPPGRVS-- 4359
PPP P+EP + + S + P LPP P KP P PPP S
Sbjct: 406 HFPPP--PEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSME 463
Query: 4360 ------------PAAAQLADTLFSKGLGPWDPPDNL 4383
P + TL S GP P D+L
Sbjct: 464 LGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSL 499
Score = 33.5 bits (75), Expect = 6.0
Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 16/71 (22%)
Query: 2900 PPQRPRFYP-----VSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPT----- 2949
PP P P V +P + P L+ PP+ PS PP PE ++ HP+
Sbjct: 1252 PPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP 1311
Query: 2950 ------PHTKG 2954
PHT G
Sbjct: 1312 LAEDHPPHTPG 1322
Score = 33.1 bits (74), Expect = 7.9
Identities = 24/60 (40%), Positives = 27/60 (45%), Gaps = 9/60 (15%)
Query: 4261 PQLGGFPGPQTGPLQELGAGPRPQGP------PRLPAPPGALSTGPVLGPVHPTPPPSSP 4314
P GFP P PL P P P P LPAPPG + P+L P+ P PP P
Sbjct: 698 PPQPGFPMPP--PLPPPPPPPPPAHPAVTVPPPPLPAPPG-VPPPPILPPLPPFPPGLFP 754
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 133 bits (335), Expect = 4e-30
Identities = 137/389 (35%), Positives = 171/389 (43%), Gaps = 84/389 (21%)
Query: 3844 GQGLMGHRLVTAQQQQQQQQHQQQGSMAGLS-HLQQSLMSHSGQPKLSAQPMGSLQQLQQ 3902
GQ L G + A Q Q +G++ H + + + Q +L Q + +LQQ QQ
Sbjct: 107 GQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQV-ALQQQQQ 165
Query: 3903 QQQLQQQQQLQQQQQQQLQQQQQL----------------QQQQLQQQQQQQQ----LQQ 3942
QQQ QQQQQ QQQQQ QQQQQ QQQQLQQQQQQQQ L
Sbjct: 166 QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHH 225
Query: 3943 QQQQQLQQQQQQLQQ----QQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQ------ 3992
Q QQQ+QQQQQQLQ+ Q QQQQQQ QQQQQQQQ L Q P QQ Q
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285
Query: 3993 ----------QQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVS-SEATEGP 4041
Q P P +P + P L P Q+ P VS ++A G
Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPP--------QSQTQPLVSQAQALPGQ 337
Query: 4042 STHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRL--PG 4099
+ PL P + P VQPQ Q Q +++Q ++ PG
Sbjct: 338 MLYTQPPLKFVRAPMVVQQPP---------------VQPQVQQQQTAVQTAQAAQMVAPG 382
Query: 4100 QQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQP-GSMTQNLLGPQQP 4158
Q +L A GG H + ++ S++P S+ LG QP ++Q+ L P
Sbjct: 383 VQMITEAL---AQGGMHIRARFPPTTAVSAIP----SSSIPLGRQPMAQVSQSSL----P 431
Query: 4159 MLERPM--QNNTGPQ--PPKPGPVLQSGQ 4183
ML P Q PQ PP P P Q GQ
Sbjct: 432 MLSSPSPGQQVQTPQSMPPPPQPSPQPGQ 460
Score = 105 bits (263), Expect = 1e-21
Identities = 169/611 (27%), Positives = 215/611 (35%), Gaps = 177/611 (28%)
Query: 3637 PGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGP- 3695
P + LQ G P A G+ + P G PGQ G G G++ P
Sbjct: 81 PMNALQSLTGGPAAGAAGIGMPPRG---PGQSLGGM--------------GSLGAMGQPM 123
Query: 3696 --SGGFFPGN--LALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQV 3751
SG PG +A S+ S + QLQLQQ LQQQQQQQQ
Sbjct: 124 SLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVA------LQQQQQQQQ--------- 168
Query: 3752 AIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQ 3811
QQQQQ L QQ Q Q Q AQ + +Q
Sbjct: 169 -FQQQQQAA-------------------------LQQQQQQQQQQQFQ-----AQQSAMQ 197
Query: 3812 QQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMA 3871
QQ Q ++ Q + L Q QQ L+ Q QQQ QQQ
Sbjct: 198 QQF-----------QAVVQQQQQLQQQQQQQQ-------HLIKLHHQNQQQIQQQQ---- 235
Query: 3872 GLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQL 3931
QQLQ+ QLQ QQQ QQQQQQQ QQQQ LQ Q
Sbjct: 236 --------------------------QQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPP 269
Query: 3932 QQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQ 3991
QQ QQ Q Q L QQ QQ+ Q Q Q QQ + + L PQ Q
Sbjct: 270 IQQPPMQQPQPPPSQALPQQLQQMHHTQHH-----QPPPQPQQPPVAQNQPSQLPPQSQT 324
Query: 3992 QQQVALGPGMPAK------PLQHFSSPGAL-GPTLLLTGKEQNTVDPAVSSEATEGPSTH 4044
Q V+ +P + PL+ +P + P + ++Q T + P
Sbjct: 325 QPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQ 384
Query: 4045 -------QGG---------PLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSS 4088
QGG A+ P S + +S S +L P P Q +
Sbjct: 385 MITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQT 444
Query: 4089 LQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSG-SSSEASSVPHLLAQPSVSLGDQPGS 4147
Q PP P Q Q S + + SG + S +S +P QPS
Sbjct: 445 PQSMPPPPQPSPQPGQPS------SQPNSNVSSGPAPSPSSFLPSPSPQPS--------- 489
Query: 4148 MTQNLLGPQQPMLERPMQNNTGPQP-PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLA 4206
Q P+ R QN + P P P PV S +M G +A+ Q L
Sbjct: 490 --------QSPVTARTPQNFSVPSPGPLNTPVNPS-------SVMSPAGSSQAEEQQYLD 534
Query: 4207 KNPQL-RHLSP 4216
K QL +++ P
Sbjct: 535 KLKQLSKYIEP 545
Score = 65.9 bits (159), Expect = 1e-09
Identities = 108/428 (25%), Positives = 160/428 (37%), Gaps = 88/428 (20%)
Query: 3460 QRLSGGPSSDLQN---------HVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQY 3510
Q L+GGP++ G G + G P PP G+ +
Sbjct: 86 QSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVS 145
Query: 3511 EEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPE-ADAEKLKLVTE 3569
QL Q+ L+ ++Q ++ + AL +Q+ ++ + + A ++ + V +
Sbjct: 146 TATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQ 205
Query: 3570 QQSKIQKQLDQVR-------------KQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAV 3616
QQ ++Q+Q Q + +QQ++ +A+ + +QQQQQQQQQQQQQQ A+
Sbjct: 206 QQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQ-QAL 264
Query: 3617 LALSPSQSPRL-------LTKLPGQLLPGHGLQ------PPQGPPGGQAGGLRLTP---- 3659
A P Q P + LP QL H Q PQ PP Q +L P
Sbjct: 265 QAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQT 324
Query: 3660 -----GGMALPG-----QPGGPFLNTALAQQQ-------QQQ----HSGGAGSLAGP--- 3695
ALPG QP F+ + QQ QQQ + A + P
Sbjct: 325 QPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQ 384
Query: 3696 -------SGGF-----FPGNLALRSLGPDSRLLQERQ--LQLQQQRMQLAQKLQQQQQQQ 3741
GG FP A+ ++ P S + RQ Q+ Q + + QQ Q
Sbjct: 385 MITEALAQGGMHIRARFPPTTAVSAI-PSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQ 443
Query: 3742 QQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGM 3801
Q Q Q +N + GP P PSS + SPQP Q P
Sbjct: 444 TPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPS----PSS----FLPSPSPQPSQSPVTA 495
Query: 3802 LGPAQVAV 3809
P +V
Sbjct: 496 RTPQNFSV 503
Score = 60.8 bits (146), Expect = 4e-08
Identities = 145/631 (22%), Positives = 216/631 (34%), Gaps = 129/631 (20%)
Query: 4046 GGPLA----IGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQ 4101
GGP A IG P PG+ SL G L QP SL QPP G
Sbjct: 90 GGPAAGAAGIGMPPRG----PGQ---SLGGMGSL-----GAMGQPMSLSGQPPPGTSGMA 137
Query: 4102 QQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLE 4161
++++ TA + QL + + Q +L Q Q QQ ++
Sbjct: 138 PHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ 197
Query: 4162 RPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQ 4221
+ Q V+Q Q L Q + Q Q ++ + Q + QQQQQ
Sbjct: 198 QQFQ-----------AVVQQQQQLQ---------QQQQQQQHLIKLHHQNQQQIQQQQQQ 237
Query: 4222 LQALLM-----------QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQ 4270
LQ + Q+Q QQ QA++ PP Q+P P+Q QPQ P Q
Sbjct: 238 LQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQP-----PMQ-----QPQP---PPSQ 284
Query: 4271 TGP--LQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQL----- 4323
P LQ++ Q PP+ PP A + L P T P S Q P Q+
Sbjct: 285 ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS-QAQALPGQMLYTQP 343
Query: 4324 PSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR-VSPAAAQLADTLFSKG--LGPWDPP 4380
P + P Q PP P + Q + V+P + + L G + PP
Sbjct: 344 PLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPP 403
Query: 4381 DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQE---------PREEPCALGAQSV 4431
L + QV+ +P S S Q+ P + G S
Sbjct: 404 TTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSS 463
Query: 4432 KREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHI 4491
+ +N AP S+ L P+ Q + A+ Q + L +N
Sbjct: 464 QPNSNVSSGPAPSPSSFLPSPSPQPS------QSPVTARTPQNFSVPSPGPLNTPVNPSS 517
Query: 4492 DSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEAL 4551
AG Q A + K K++ K + L R+ + K D +
Sbjct: 518 VMSPAGSSQ------------AEEQQYLDKLKQLSKYIEPL---RRMINKIDKNEDRKKD 562
Query: 4552 LKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLL 4611
L ++K L + LT+P+ CP+ + A
Sbjct: 563 LSKMKSLLDI--LTDPS------------KRCPLKTLQKCEIALEK-------------- 594
Query: 4612 TKNNLSNPPTPPSSLPPTPPPSVQQKMVNGV 4642
KN+++ P PP +PPT + Q +++ V
Sbjct: 595 LKNDMAVPTPPPPPVPPTKQQYLCQPLLDAV 625
Score = 59.7 bits (143), Expect = 8e-08
Identities = 78/338 (23%), Positives = 126/338 (37%), Gaps = 50/338 (14%)
Query: 393 QGQPKGGHVTSMQPKEPGPLQCEAKPLGK-AGVQLEPQLEAPLNEEMPLLPPPE-ESPLS 450
Q Q + H+ + + +Q + + L + A +QL+ Q + ++ + + P+
Sbjct: 212 QQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ 271
Query: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESS 510
PP + P PP +A P++L + H P + P PP ++ S P S
Sbjct: 272 QPPMQQPQPPPSQAL-----PQQL--QQMHHTQHHQPPPQ--PQQPPVAQNQPSQLPPQS 322
Query: 511 PFSPLEESPLSPPEE----SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP 566
PL + P + PP + P+ + P+ P ++ + +
Sbjct: 323 QTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV--QQPPVQPQVQQQQTAVQTAQAAQMVA 380
Query: 567 PEASRLSP-------------PPEESPMSPPPEESPMSPPPEA--SRLFPPFEESPLSPP 611
P ++ PP + + P P+ P A S+ P SP
Sbjct: 381 PGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQ 440
Query: 612 PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671
++P S PP PP+ SP P P S VS P P S P P
Sbjct: 441 QVQTPQSMPP-------PPQPSPQPGQPSSQPNS---NVSS-GPAPSPSSFLPSP----- 484
Query: 672 SPPPEESPTS--PPPEASRLSPPPEDSPTSPPPEDSPA 707
SP P +SP + P S SP P ++P +P SPA
Sbjct: 485 SPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 522
Score = 57.4 bits (137), Expect = 4e-07
Identities = 67/280 (23%), Positives = 106/280 (37%), Gaps = 38/280 (13%)
Query: 803 ELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSP 862
+L L Q ++ ++ L QP P + P P+P S P+ +
Sbjct: 243 QLQLQQQQQQQQQQQQQQQQALQAQP------PIQQPPMQQPQPPPSQALPQQLQQMHHT 296
Query: 863 RPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPS-- 920
+ +PP +P Q P + P PP + PL+ + A + PG+ + P + +P
Sbjct: 297 QHHQPPPQPQQPPVAQNQPSQLPP-QSQTQPLVSQ-AQALPGQMLYTQPPLKFVRAPMVV 354
Query: 921 GEPSLSPQLMPPDP----------LPPPLSPIITAAA----------PP--ALSPLGELE 958
+P + PQ+ + P + I A A PP A+S +
Sbjct: 355 QQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSS 414
Query: 959 YPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILP-PSPGSPVG-PASPIL 1016
P G + P + ++ L SP P P+ +PP P P PG P P S +
Sbjct: 415 IPLGRQ----PMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVS 470
Query: 1017 MEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLS 1056
P P S L S P SP + +P + P PL+
Sbjct: 471 SGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLN 510
Score = 57.0 bits (136), Expect = 5e-07
Identities = 59/262 (22%), Positives = 96/262 (36%), Gaps = 32/262 (12%)
Query: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE 550
+ P+ PP + P PP ++ P L++ + + PP P + P + S L P +
Sbjct: 267 QPPIQQPPMQQPQPPPSQALP-QQLQQMHHTQHHQPPPQP--QQPPVAQNQPSQLPPQSQ 323
Query: 551 ESPLSPPPEELP-----TSPPPEASRLSPPPEESPMSPPPEESPMS-PPPEASRLFPPFE 604
PL + LP T PP + R ++ P+ P ++ + +A+++ P
Sbjct: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV 383
Query: 605 E---SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP-EESPMSPPPEVSRLSP---LP 657
+ L+ PP + + P P+ P + S P +S SP +
Sbjct: 384 QMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQ 443
Query: 658 VVSRLSPPPEESPLSPPPEESPTS-----PPPEASRLSPPPEDSPTSPP----------- 701
+ PPP+ SP P P S P P S P P P+ P
Sbjct: 444 TPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSV 503
Query: 702 PEDSPASPPPEDSLMSLPLEES 723
P P + P S + P S
Sbjct: 504 PSPGPLNTPVNPSSVMSPAGSS 525
Score = 55.1 bits (131), Expect = 2e-06
Identities = 65/263 (24%), Positives = 100/263 (38%), Gaps = 56/263 (21%)
Query: 3253 LEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQ 3312
++ ++++LQ+ QL Q Q QQQQQQQQQ L A P Q + PS A QQ
Sbjct: 231 IQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQL 290
Query: 3313 LSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQS 3372
+ QP P P QPP + NQ + L PQ
Sbjct: 291 QQMHHTQHHQP----PPQPQQPP-------------VAQNQ----------PSQLPPQSQ 323
Query: 3373 SQPVLSQ------KPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAK 3426
+QP++SQ + + T PP ++ + Q P + +
Sbjct: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ--------PPVQPQVQQQQTAVQTAQA 375
Query: 3427 AKMVA--LKGIKKVMAQGSIGV---------APGMNRQQVSLLAQRLSGGPSSDLQNHVA 3475
A+MVA ++ I + +AQG + + + + L Q ++ S L +
Sbjct: 376 AQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSS 435
Query: 3476 AGSGQE----RSAGDPSQPRPNP 3494
GQ+ +S P QP P P
Sbjct: 436 PSPGQQVQTPQSMPPPPQPSPQP 458
Score = 52.4 bits (124), Expect = 1e-05
Identities = 70/300 (23%), Positives = 113/300 (37%), Gaps = 55/300 (18%)
Query: 2334 RASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPE 2393
+A Q +P ++ +PPP+QAL P + +T + QPP P+ P
Sbjct: 262 QALQAQPPIQQPPMQQPQPPPSQAL-------PQQLQQMHHTQHH-QPPPQPQQPPVAQN 313
Query: 2394 SCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP 2453
LPP+S S+ A P +Q PL F +P+ +P
Sbjct: 314 QPSQLPPQSQTQPLVSQAQALPGQMLYTQPPL--------KFVRAPMV--------VQQP 357
Query: 2454 PSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHA----K 2509
P +PQ + + Q ++ + +L GG P + A
Sbjct: 358 PVQPQVQQQQTAVQ---TAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSS 414
Query: 2510 VPSGQPPNFVRSPGTGAFVGTPSP-MRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGP 2568
+P G+ P S + + +PSP + PQ++ P P PQPG P NS+
Sbjct: 415 IPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPP--PQPSPQPGQPSSQP-NSNVSS 471
Query: 2569 GPTLGKPQSTNYTVATGNFHPSGSP---LGPSSGSTGESYGL-------SPLRPPSVLPP 2618
GP + +F PS SP P + T +++ + +P+ P SV+ P
Sbjct: 472 GP----------APSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSP 521
Score = 49.3 bits (116), Expect = 1e-04
Identities = 55/233 (23%), Positives = 86/233 (36%), Gaps = 45/233 (19%)
Query: 374 PPEPGDTPT--DEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQL---EP 428
PP+P P ++P L Q QP + S PG + PL + +P
Sbjct: 302 PPQPQQPPVAQNQPSQLPPQSQTQP----LVSQAQALPGQMLYTQPPLKFVRAPMVVQQP 357
Query: 429 QLEAPLNEEMPLLPPPEESPLSPPPEESPTSP------------PPEASRLSPPPEELPA 476
++ + ++ + + + + P + T PP + + P +P
Sbjct: 358 PVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPL 417
Query: 477 S--PLPEALHLSRPLEESP-----------LSPPPEESPLSPPPESSPFSPLEESPLSPP 523
P+ + S P+ SP + PPP+ SP P S P S + P P
Sbjct: 418 GRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSP 477
Query: 524 EESPPSPALETPLSPPPEASPLS--PPFEESPLSPPPEELPTSPPPEASRLSP 574
PSP SP P SP++ P S SP P P +P +S +SP
Sbjct: 478 SSFLPSP------SPQPSQSPVTARTPQNFSVPSPGPLNTPVNP---SSVMSP 521
Score = 48.1 bits (113), Expect = 2e-04
Identities = 62/238 (26%), Positives = 87/238 (36%), Gaps = 31/238 (13%)
Query: 2275 PPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFK---APL 2331
PPP + ++ + + PS PP S L G L T K AP+
Sbjct: 301 PPP--------QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPM 352
Query: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
+ V+PQ Q AQ +AP T+ AQ + R + PP
Sbjct: 353 VVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQM---------ITEALAQGGMHIRARFPP 403
Query: 2392 PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451
+ A+P S+ P R P + SQSS +P P S P SP P
Sbjct: 404 TTAVSAIPSSSI---PLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQP-G 459
Query: 2452 RPPSRPQSRDPFAPLHKP------PRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503
+P S+P S P P P PQP + A + + S+ + G P P P+
Sbjct: 460 QPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPG-PLNTPVNPS 516
Score = 47.0 bits (110), Expect = 5e-04
Identities = 55/217 (25%), Positives = 80/217 (36%), Gaps = 17/217 (7%)
Query: 3188 TGGPPAHLL-TPSPLSGPGGS-SLLEKFELESGALTLPGGPAASGDELDKMESSLVASEL 3245
TGGP A P GPG S + ++L G P + ++V++
Sbjct: 89 TGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTAT 148
Query: 3246 PLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPS 3305
P L + ++ Q++QQ Q Q A QQQQQQQQ A A +
Sbjct: 149 PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQF------QA 202
Query: 3306 LAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQA 3365
+ QQQL +Q Q L+ H QQ++ + + Q Q
Sbjct: 203 VVQQQQQLQ------QQQQQQQHLIKLH---HQNQQQIQQQQQQLQRIAQLQLQQQQQQQ 253
Query: 3366 GLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQL 3402
QQ Q + +Q P+ P P A+ QQL
Sbjct: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQL 290
Score = 46.6 bits (109), Expect = 7e-04
Identities = 59/259 (22%), Positives = 103/259 (39%), Gaps = 21/259 (8%)
Query: 634 PMSPPPEESPMSPPPEV--SRLSPLPVVSRLSPPPEESPLSPP-PEESPTSPPPEASRLS 690
P+ PP + P PP + +L + PPP+ P PP + P+ PP++ +
Sbjct: 269 PIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ--PQQPPVAQNQPSQLPPQSQ--T 324
Query: 691 PPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEP 750
P + P + PP + + +++ P+ P ++ Q ++ P
Sbjct: 325 QPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQ 384
Query: 751 HLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP--EEPHLS-PQAEGPHLS-PQPEELHL 806
++ + + +A P + P ++P +P Q+ P LS P P +
Sbjct: 385 MITEALAQGGMHIRARFPPTTAVSAIPS-SSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQ 443
Query: 807 SPQTEEPHLSPVPEEPCLSPQPEES-----HLSPQSEEPCLSPRPEESHL---SPELEKP 858
+PQ+ P P P+ S QP + SP S P SP+P +S + +P+
Sbjct: 444 TPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSV 503
Query: 859 PLSPRPEKPPEEPGQCPAP 877
P SP P P P +P
Sbjct: 504 P-SPGPLNTPVNPSSVMSP 521
Score = 46.2 bits (108), Expect = 9e-04
Identities = 71/312 (22%), Positives = 122/312 (39%), Gaps = 45/312 (14%)
Query: 2678 EKQRQRQRLRELLIRQQIQRNTLRQEKETAA--AAAGAVGPPGSWGAEPSSPAFEQLSRG 2735
++Q+Q QR+ +L ++QQ Q+ +Q+++ A A PP +P P + L +
Sbjct: 233 QQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQ---QPQPPPSQALPQQ 289
Query: 2736 QTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS 2795
TQ PP P+ + ++ S+ PP + + ++ L G
Sbjct: 290 LQQMHHTQHHQP----PPQPQQPPV-------AQNQPSQLPPQSQTQPLVSQAQALPG-- 336
Query: 2796 QAFYQRAPYP---GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGS 2852
Q Y + P + +QQ Q QQQ TA + + A PG ++ +AL
Sbjct: 337 QMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV----APGVQMITEALAQ 392
Query: 2853 PLAGISTRLPGPG--EPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVS 2910
I R P +P + P + Q L +P PGQ Q P+ P
Sbjct: 393 GGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQ-QVQTPQSMPPP 451
Query: 2911 EDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPT---LPTGLELVNRP 2967
P +P+ P +PS+ P +++ P+P + P+ P+ + R
Sbjct: 452 PQP---SPQ-----------PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTART 497
Query: 2968 PSSTELGRPNPL 2979
P + + P PL
Sbjct: 498 PQNFSVPSPGPL 509
Score = 45.8 bits (107), Expect = 0.001
Identities = 59/242 (24%), Positives = 97/242 (40%), Gaps = 30/242 (12%)
Query: 395 QPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQL---EAPLN-EEMPLLPPPEESPLS 450
QP+ V QP + P Q + +PL L Q+ + PL P++ ++ P+
Sbjct: 304 QPQQPPVAQNQPSQLPP-QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV--QQPPVQ 360
Query: 451 PPPEESPTS-PPPEASRLSPPPEELPASPLPEA-LHLSRPLEESPLSPPPEESPLSPPPE 508
P ++ T+ +A+++ P ++ L + +H+ PP + + P
Sbjct: 361 PQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARF-------PPTTAVSAIPSS 413
Query: 509 SSPFS--PLEE-SPLSPPEESPPSPA--LETPLSPPPEASPLSPPFEESPLSPPPEELPT 563
S P P+ + S S P S PSP ++TP S PP P P + P S P + +
Sbjct: 414 SIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQ--PSSQPNSNVSS 471
Query: 564 SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA 623
P P S P SP P+ S + F PL+ P S + P +
Sbjct: 472 GPAPSPSSFLP-------SPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 524
Query: 624 SR 625
S+
Sbjct: 525 SQ 526
Score = 40.4 bits (93), Expect = 0.049
Identities = 51/252 (20%), Positives = 87/252 (34%), Gaps = 30/252 (11%)
Query: 893 PLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALS 952
P + +P + +P PP LP++L + + PP P P P + P L
Sbjct: 268 PPIQQPPMQQPQPPPSQALPQQLQ-----QMHHTQHHQPP---PQPQQPPVAQNQPSQLP 319
Query: 953 PLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPA 1012
P + + P ++ + P L + P+ PV P + A
Sbjct: 320 PQSQTQ-PLVSQAQALPGQMLYT---QPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQA 375
Query: 1013 SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHE 1072
+ ++ + L Q + + P P ++PS P+G+ A++ +
Sbjct: 376 AQMVAPGVQMITEALAQGGMHIRARFP----PTTAVSAIPSSSIPLGR----QPMAQVSQ 427
Query: 1073 METEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDF---SGLGEDTAPLDGID 1129
+S P P + +P P P PSP P S + AP
Sbjct: 428 SSLPMLSSPS-PGQQVQTPQSMPPP------PQPSPQPGQPSSQPNSNVSSGPAPSPSSF 480
Query: 1130 APGSQPEPGQTP 1141
P P+P Q+P
Sbjct: 481 LPSPSPQPSQSP 492
Score = 39.7 bits (91), Expect = 0.084
Identities = 59/248 (23%), Positives = 91/248 (36%), Gaps = 20/248 (8%)
Query: 2749 VGLPPSKLSGPILGPGSFPSDDR---LSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYP 2805
+G+PP + G GS + + LS PPP T S M +S +V + Q
Sbjct: 99 IGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGT-SGMAPHSMAVVSTATPQTQLQLQQ 157
Query: 2806 GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPG 2865
+L QQQQQQ QQQQA + +F QA S + +
Sbjct: 158 VALQQQQQQQQFQQQQQAALQQQQQQQQQQQF----------QAQQSAMQQQFQAVVQQQ 207
Query: 2866 EPVPGPAGPAQ-FIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGL 2924
+ + Q I+L H Q+ + Q + + + + L+
Sbjct: 208 QQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ 267
Query: 2925 AVSGLPP-QKPSAPPA---PELNNSLHPTPHTKGPTLPTGLELV-NRPPSSTELGRPNPL 2979
PP Q+P PP+ P+ +H T H + P P + N+P + PL
Sbjct: 268 PPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPL 327
Query: 2980 ALEAGKLP 2987
+A LP
Sbjct: 328 VSQAQALP 335
Score = 36.6 bits (83), Expect = 0.71
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE 4943
P P+P Q + N +V P+P PS PSP+ P++ V T
Sbjct: 450 PPPQPSPQPGQPSSQPNSNVSS-------GPAPSPSSFLPSPSPQPSQSPVTARTPQNFS 502
Query: 4944 PPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQ 5003
P P PL +P S + E E +LK+ R++ I K R+
Sbjct: 503 VPSPGPLNTPVNPSSVMSPAGSSQAE--EQQYLDKLKQLSKYIEPLRRMINKIDKNEDRK 560
Query: 5004 EDEREVAEFMEQL 5016
+D ++ ++ L
Sbjct: 561 KDLSKMKSLLDIL 573
Score = 36.2 bits (82), Expect = 0.93
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 2/74 (2%)
Query: 4904 RQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPT-EPLAEPPVPSPLPLASSPESARPK 4962
+Q+ P P P PSP P+S P + P P + P PSP P + SP +AR
Sbjct: 440 QQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQP-SQSPVTARTP 498
Query: 4963 PRARPPEEGEDSRP 4976
P G + P
Sbjct: 499 QNFSVPSPGPLNTP 512
Score = 34.3 bits (77), Expect = 3.5
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 9/84 (10%)
Query: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS--PASPPTEPLVE----LPTE 4939
P+PP + + + Q PPP+ PP + PS P T+PLV LP +
Sbjct: 278 PQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQ 337
Query: 4940 PLAEPPVPSPLPLASSPESARPKP 4963
L P PL +P + P
Sbjct: 338 MLYTQP---PLKFVRAPMVVQQPP 358
Score = 34.3 bits (77), Expect = 3.5
Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 6/86 (6%)
Query: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEP--SPPPSPLAPSPASPPTEPLVELPTEPL 4941
P+ P VS + LS+P P + +P P P P+ P +P + P +
Sbjct: 411 PSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ-PNSNV 469
Query: 4942 AEPPVPSPLPLASSPESARPKPRARP 4967
+ P PSP SP P+P P
Sbjct: 470 SSGPAPSPSSFLPSPS---PQPSQSP 492
Score = 33.9 bits (76), Expect = 4.6
Identities = 77/405 (19%), Positives = 129/405 (31%), Gaps = 36/405 (8%)
Query: 1967 GEPDS----PWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVL 2022
G+P S P G+ G P + +T L Q +LQ+ ++ ++ Q
Sbjct: 120 GQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQ----- 174
Query: 2023 YANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAES 2082
A + +Q + ++ + + ++ V + Q+ + ++ Q+Q +
Sbjct: 175 -AALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQ 233
Query: 2083 QINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGF 2142
Q + ++ + + + + Q AL + PP P + P L
Sbjct: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQM 293
Query: 2143 LKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLE-------------PRF 2189
P + P Q+P Q +Q A A P + P
Sbjct: 294 HHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMV 353
Query: 2190 PTAPPTYPPYPSP-----TGAPAQPPMLGASSRPGAGQPGEFHTT---PPGTPRHQ-PST 2240
PP P T AQ G A G H PP T PS+
Sbjct: 354 VQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSS 413
Query: 2241 PDPFLKPRCPSLDNLAVP--ESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPS 2298
P + + ++P SP G + P PPP S + + + S
Sbjct: 414 SIPLGRQPMAQVSQSSLPMLSSPSPGQ-QVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG 472
Query: 2299 YGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLT-PRASQVEPQS 2342
P F+ SPS + +TP F P P + V P S
Sbjct: 473 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 517
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 133 bits (334), Expect = 6e-30
Identities = 255/1018 (25%), Positives = 354/1018 (34%), Gaps = 204/1018 (20%)
Query: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPE 499
L+PPP P PP++ S PP S L PP P P P L P +P PPP
Sbjct: 138 LIPPPPPGPAPGPPQD--ISEPPGGSPLPSPPSTAPPPP-PLLLEPPPPPSMAP-PPPPV 193
Query: 500 ESPLSPPPE-SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP----- 553
LSPP SSP P +PP+ PP+P L PPP +PP SP
Sbjct: 194 LEALSPPHTLSSPSIP------TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT 247
Query: 554 -LSPP-------PEELPTSPPPEASRLSPP-----PEESPMSPPPE------ESPMSPPP 594
L PP + EA+R SPP P+ S + P PE S PPP
Sbjct: 248 RLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307
Query: 595 EASRLFP-PFEESPLSPPPEESPLSPPPEASRLSPP----------PEDSPMSPPPEESP 643
R P +E+ +P EE P L P P+ +P P E
Sbjct: 308 TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELK 367
Query: 644 MSPP--PEVSRLSPLPVVSRLSPPPEESPLSPP----PEESPTSPP-----PEASRLSPP 692
+ P P + + S R PP PL PP P +P PP P A + + P
Sbjct: 368 ATAPASPRLGQ-SQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
Query: 693 P-----EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL-SPR 746
P +SP + P P PE++ S P++ P + + +L R
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD----PSQMEKLRNELAAYLCGSR 482
Query: 747 PEEPHLSPRPEEPHLSPQAEEPHLSPQ-PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805
E+ LS RP P ++PQ++E P+ PE+ L ++P + E E
Sbjct: 483 REDRFLSHRP-GPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETE 541
Query: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
+P P + +P++ SP P + + E S +E+ KP + P
Sbjct: 542 AAPSLTLPSVDYIPQD---SPTPSVRQIRNELEARLSSAAEKEA-------KPSIGSLPP 591
Query: 866 KPPEEPGQC------------PAPEELP-----LFPPPG---EPSLSPLLGEPALSEPGE 905
KP E G+ P + LP L P + L P + A EP
Sbjct: 592 KPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAI 651
Query: 906 PPLSPL----PEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPF 961
PP + L P + L P+ L P PL P I + A + +L
Sbjct: 652 PPKATLWPATPPKATLGPA--TPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEK 709
Query: 962 GAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM------ILPPSPGSPVGPASPI 1015
+ PE P A+ + TP E + ++ +P PP SP G P
Sbjct: 710 DSGPAGQPEKP-ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKT-SPGGGEVPC 767
Query: 1016 LMEPLPPQCS----------PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVS 1065
L +P Q S L + P PP LP P+ P +
Sbjct: 768 LYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQP-------T 820
Query: 1066 DEAELHEMETEKVSEPECPALEPSA---------------TSPLPSPMGDLSCPAPSPAP 1110
DE H + E V AL +A S LP + D S A + +
Sbjct: 821 DELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSD 880
Query: 1111 ALDDFSGLGEDTAPLDGI------DAPGSQPEPGQTPGSLASELKGSPV-----LLDPEE 1159
++ G + + D+P + P + L + +G+ + PE
Sbjct: 881 SIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEP 940
Query: 1160 LAPVTPMEV--------YPECKQTAGQGSPC----EEQEEPRAPVAPTPPTLIKSDIVNE 1207
APV V +P K + SP EE+EE V P PP E
Sbjct: 941 QAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPP---------E 991
Query: 1208 ISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPET 1267
SN DPE LG + P + LR ++ P
Sbjct: 992 FSN--------------------DPEPPAPALQYLGRQSS-PPRNNYSDLRQLPNAGPGA 1030
Query: 1268 DDSLLCDAGTAISGGKAEGEKGRRR-SSPARSRIKQGRSSSFPGRRRPRGGAHGGRGR 1324
+L A G + G G R S RS IK+ P R G HGG GR
Sbjct: 1031 PPALGFSRFPA--GARYAGAGGLERFSGGGRSLIKKRLYVGEP--HRGPGLPHGGTGR 1084
Score = 83.2 bits (204), Expect = 7e-15
Identities = 240/1010 (23%), Positives = 322/1010 (31%), Gaps = 213/1010 (21%)
Query: 2066 DNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIF 2125
D+ A + + + VGD+ L + PP A G P + P
Sbjct: 101 DDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEP--- 157
Query: 2126 IGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPF--GLAPAY 2183
P G P S P P L PP P+ P P L+P +
Sbjct: 158 ------PGG----------SPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201
Query: 2184 PL-EPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTT--PPGTPRHQPST 2240
L P PT P PP P PP + A + P P T PPG S
Sbjct: 202 TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKS- 260
Query: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKA----SEPLLS-------PPPFG------ESRK 2283
D L R + P SP G A EP L+ PPP ++
Sbjct: 261 -DVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQE 319
Query: 2284 ALEVKKEELGAS--SPSYGPPNLGFVDSPSSGTHLG-GLELKTPDVFK--APLTPRASQV 2338
A E ++E GA+ +PS P F P+S + E P K AP +PR Q
Sbjct: 320 AQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS 379
Query: 2339 EPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCAL 2398
+ Q+ R PPPA P PP P + P PPL P P P A
Sbjct: 380 QSQADE---RAGTPPPA---PPLPPPAPPL--------PPPAPPLPPAAPPLPCAQKAAH 425
Query: 2399 PPRSLPSDPFSRVPA--------SPQSQSSSQSPLTPRPLS---------AEAFCPSPVT 2441
PP P S PA SP++ +SS +P+ R S A C S
Sbjct: 426 PPAGFTKTPKSSSPALKPKPNPPSPENTASS-APVDWRDPSQMEKLRNELAAYLCGSRRE 484
Query: 2442 PRFQS--PDPYSRPPSRPQSRDPFAP-----LHKPPRPQPPEVAFKA---GSLAHTSL-- 2489
RF S P P P S+ + P P L P + PP V K+ SL T
Sbjct: 485 DRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAP 544
Query: 2490 -----GAGGFPAALPA--------------GPAGELHAKVPSGQPPNFVRSPG-----TG 2525
P P A E AK G P R G G
Sbjct: 545 SLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENG 604
Query: 2526 A---------------FVGTPSPMRFTFPQAVGEPSLKP-PVPQPGLPPPHGINSHFGPG 2569
A T P P+A+ P++ P P+P +PP + P
Sbjct: 605 ADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPK 664
Query: 2570 PTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSP---LRPPSVLPPPAPDGSLP 2626
TLG +T +G P + GP+ ST + + + P P+
Sbjct: 665 ATLG--PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPAS 722
Query: 2627 YLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRL 2686
SQ G SP E P G SS A P PG + Q
Sbjct: 723 QEVSTPSQARGEGSPSEATRLPTQGARSS---AAFPPKTSPGGGEVPCLYKPHCHQSSLS 779
Query: 2687 RELLIRQQIQRNTLRQEKETAAAAAGAVGP--PGSWGAEPSSPAFEQLSRGQTPFAGTQD 2744
RE+ + A GA GP P P PA P A Q
Sbjct: 780 REVAVVM------------PTLARGGAAGPGEPVEVKEPPGLPA--------KPPASAQP 819
Query: 2745 KSSLVGLPPSKLSGPILGPGS-----FPSDDRLSRPPP-------PATPSSMDVNSRQLV 2792
L+ P ++G ++ GS + R + + P S+ +S Q
Sbjct: 820 TDELLRHP---VTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAE 876
Query: 2793 GGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGS 2852
S + + P S + + + ++ ++ P+ GP LGR A G+
Sbjct: 877 ASSDSIFHSQGTPNSFTVVPKLPKEAEKDS---------PLTTEIPNKWGPRLGRDAEGT 927
Query: 2853 PLA-GISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTP----------FPGQGPP 2901
L+ + P P PV + H + K +P F + P
Sbjct: 928 ELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIP 987
Query: 2902 QRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQK------------PSAPPA 2939
P F S DP AP L+ L PP+ P APPA
Sbjct: 988 PPPEF---SNDPEPPAP-ALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPA 1033
Score = 66.2 bits (160), Expect = 8e-10
Identities = 123/451 (27%), Positives = 168/451 (37%), Gaps = 102/451 (22%)
Query: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
PGQ ++L + PPP P+ P +SEP P SPLP SP PS +P
Sbjct: 130 PGQYG--QDLLIPPPPPGPAPGP---PQDISEP--PGGSPLP-----SP---PSTAP--- 171
Query: 931 PPDPL--PPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETP---ISP- 984
PP PL PP P + PP L L P L++P + TP I P
Sbjct: 172 PPPPLLLEPPPPPSMAPPPPPVLEAL-------------SPPHTLSSPSIPTPPDFIPPA 218
Query: 985 PPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH--SLVPQNSPPSQC 1042
PP A P P P PP+P SP + + PP + +L + + ++
Sbjct: 219 PPLAFLAPPPPPVPAPAPPAPASPHTVGTRL----FPPGGVTKWKSDVALNGRQAEATRA 274
Query: 1043 SPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEP--------------ECPALEP 1088
SPP SP P G +G + E L + KV P E P E
Sbjct: 275 SPPR------SPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEE 328
Query: 1089 SATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPG-------SQPEPGQTP 1141
AT PS + P P P+ + S + D AP D PG + P GQ+
Sbjct: 329 GATKKAPSRL-----PLP-PSFHIRPASQVYPDRAPEP--DCPGELKATAPASPRLGQSQ 380
Query: 1142 GSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIK 1201
S A E G+P P L P P P P P AP P K
Sbjct: 381 -SQADERAGTPPPAPP--LPPPAP---------------PLPPPAPPLPPAAPPLPCAQK 422
Query: 1202 SDIVNEISNLSQGDASASFPGSEPLLGSPDPEG-GGSLSMELGVSTDVSPARDEGSLRLC 1260
+ + + ++ S+S P +P P PE S ++ + + R+E + LC
Sbjct: 423 A--AHPPAGFTKTPKSSS-PALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLC 479
Query: 1261 TDSLPETDDSLLCDAGTAISGGKAEGEKGRR 1291
D L G ++ EG+KG R
Sbjct: 480 GSR--REDRFLSHRPGPTVAPQSKEGKKGPR 508
Score = 63.2 bits (152), Expect = 7e-09
Identities = 118/499 (23%), Positives = 167/499 (33%), Gaps = 104/499 (20%)
Query: 4534 SSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRG 4593
S L+ VR L QE L + P++ +F+ G+ VNG +L
Sbjct: 64 SGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYS 123
Query: 4594 AFGSGALPTGPDYYSQLLT------------KNNLSNPP------TPPSSLPPTPPPSVQ 4635
+ G P Y Q L ++S PP +PPS+ PP PP ++
Sbjct: 124 SVGD----LRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLE 179
Query: 4636 QKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMES 4695
P + P A L S D + P PP + +
Sbjct: 180 PP------PPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP--PAPP------LAFLA 225
Query: 4696 DEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDT 4755
P PA + +G FP G +W+ D AL+ RAS P P
Sbjct: 226 PPPPPVPAPAPPAPASPHTVGTRL--FPPGGVTKWKS-DVALNGRQAEATRASPPRSPAE 282
Query: 4756 KPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSY 4815
ALG P P T+ + S K+P
Sbjct: 283 PKGSALG---PNPEPHLTFPR-------------------------------SFKVP--- 305
Query: 4816 EVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDI 4875
P +P R + P + E P KE+G K+P P + P + ++ +
Sbjct: 306 ----PPTPVRTSSIPVQEAQEAPR-KEEGATKKAPSRLP--------LPPSFHIRPASQV 352
Query: 4876 LSLLKQESPAPEPPTQHSYTYNVS-NLDVRQLSA------PPPEEPSPPPSPLAPSPASP 4928
+P P+ P + T S L Q A PPP P PPP+P P PA P
Sbjct: 353 YP---DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP 409
Query: 4929 PTEPLVELP-TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKG-VR 4986
LP + A PP SS + +PKP PE S P W+ +
Sbjct: 410 LPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAP---VDWRDPSQ 466
Query: 4987 WKRLRLLLTIQKGSGRQED 5005
++LR L R+ED
Sbjct: 467 MEKLRNELAAYLCGSRRED 485
Score = 58.9 bits (141), Expect = 1e-07
Identities = 167/769 (21%), Positives = 247/769 (32%), Gaps = 98/769 (12%)
Query: 4267 PGPQTGPLQEL----GAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPP----------- 4311
PGP GP Q++ G P P P P PP L P + P PPP
Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTL 203
Query: 4312 SSPQEPKRPSQLPSPSSQLPTEAQLPP--THPGTPKPQGP----TLEPPPGRVSPAAAQL 4365
SSP P P +P P+ L A PP P P P P T PPG V+ + +
Sbjct: 204 SSPSIPTPPDFIP-PAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDV 262
Query: 4366 ADTLFSKGLGPWDPPDNLAETQKPEQSSLVPG---HLDQVNGQVVPEASQLSIKQEPREE 4422
A PP + AE P+ S+L P HL VP + + P +E
Sbjct: 263 ALNGRQAEATRASPPRSPAE---PKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQE 319
Query: 4423 PCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEG 4482
AQ R+ G AP P + H+ + G
Sbjct: 320 -----AQEAPRKEEGATKKAPSRL-------PLPPSFHIRPASQVYPDRAPEPDCPGELK 367
Query: 4483 LRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKE 4542
A + + + +++ P PL P + A+ L ++K
Sbjct: 368 ATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPP 427
Query: 4543 DGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPT 4602
G + +L P P N + AP P + +LR A
Sbjct: 428 AGFTKTPK-----SSSPALKPKPNPPSPENTASSAPVDWRDP-SQMEKLRNEL--AAYLC 479
Query: 4603 GPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSE 4662
G + L ++ P P S P + +K P+++ P
Sbjct: 480 GSRREDRFL--SHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDT---PPGVPEKSLGG 534
Query: 4663 RALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRF 4722
+L +T SL L + P + T VR +E S + SI G P+
Sbjct: 535 SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSI-GSLPPK- 592
Query: 4723 PHLGSGR----WEQEDRALSPVIPLIPRASIPVFPDT--KPYGALGLEVPGKL------- 4769
P L GR +D+ PV +P S + P T +P LG +P K
Sbjct: 593 PRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIP 652
Query: 4770 ----------------PVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPN 4813
P T + G + T A A + ++L++ K +
Sbjct: 653 PKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEK--D 710
Query: 4814 SYEVLFPESPA-RAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQ 4872
S PE PA + + P + EG + L P + A P T
Sbjct: 711 SGPAGQPEKPASQEVSTPSQARGEGSPSEATRL--------PTQGARSSAAFPPKTSPGG 762
Query: 4873 LDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEP 4932
++ L K + + P E PP P P ++ PT+
Sbjct: 763 GEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDE 822
Query: 4933 LVELP-TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLK 4980
L+ P T + E P L LA+ + K R+ G S P L+
Sbjct: 823 LLRHPVTGEVVERGSPMALLLAARQRA--QKGRSVGAALGRSSLPGSLR 869
Score = 57.0 bits (136), Expect = 5e-07
Identities = 212/933 (22%), Positives = 289/933 (30%), Gaps = 181/933 (19%)
Query: 4126 EASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGL 4185
EA S PH L+ PS+ T P P P+ P PP P P
Sbjct: 195 EALSPPHTLSSPSIP--------TPPDFIPPAP----PLAFLAPPPPPVPAPAP------ 236
Query: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245
P TVG GV + + L RQ + ++A P +
Sbjct: 237 PAPASPHTVGTRLFPPGGVT-------------KWKSDVALNGRQAEATRASPPRSPAEP 283
Query: 4246 PGTQTSPLQGLLGCQPQLGGFPGP-----QTGPLQELGAGPRPQ------GPPRLPAPPG 4294
G+ P P+ P P + P+QE PR + P RLP PP
Sbjct: 284 KGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP- 342
Query: 4295 ALSTGPVLGPVHP--TPPPSSPQEPKRPS----QLPSPSSQLPTEAQLPPTHPGTPKPQG 4348
+ P V+P P P P E K + +L SQ A PP P P P
Sbjct: 343 SFHIRPA-SQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPP-A 400
Query: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVP 4408
P L PP + PAA L + PP +T K +L P
Sbjct: 401 PPLPPPAPPLPPAAPPLPCAQKAA-----HPPAGFTKTPKSSSPALKPK----------- 444
Query: 4409 EASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLL--LAGPRSEAGHLLLQKL 4466
P E A A R+ P N L L G R E L +
Sbjct: 445 -------PNPPSPENTASSAPVDWRD----PSQMEKLRNELAAYLCGSRREDRFLSHRP- 492
Query: 4467 LRAKNVQLSTGRGSEGLRAEINGHIDSKLA-----GLEQKLQGTPSNKEDAAARKPLTPK 4521
V + G +G R + S A G+ +K G S E AA P
Sbjct: 493 --GPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPS 550
Query: 4522 PKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLP----LTEPAITANFS--- 4574
+ + D S +++R E R S A K+ K + LP L I N +
Sbjct: 551 VDYIPQ--DSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDD 608
Query: 4575 -LFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSL--PPTPP 4631
L P P + L GP + P PP + P TPP
Sbjct: 609 KLSKPVAKNLPPQSTTLLPTTSLQPKAMLGP-----AIPPKATPEPAIPPKATLWPATPP 663
Query: 4632 -----PSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHN 4686
P+ K +G T + P A++A K P
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQ 723
Query: 4687 QTEDVRMESDEDSDSPDSIVPASSPESIL---------GEEAPRF--PHLGSGRWEQEDR 4735
+ E S S + +P S G E P PH +E
Sbjct: 724 EVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE-- 781
Query: 4736 ALSPVIPLIPRASI------------PVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVS 4783
++ V+P + R P P P A + + PVT +GS ++
Sbjct: 782 -VAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
Query: 4784 VMLTVSAAAAKNLN-GVMVAVAELL-------------------SMKIPNSYEVLFPESP 4823
++L A K + G + + L S PNS+ V+ P+ P
Sbjct: 841 LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV-PKLP 899
Query: 4824 ARAGTE-PKKGEAEGPGGKEKG--LEGKSPDTGPDWLKQ-------FDAVLPGYTLKSQL 4873
A + P E G G EG +W K ++ V P +
Sbjct: 900 KEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGH- 958
Query: 4874 DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS------PAS 4927
L K S P P + N +V PPP E S P P AP+ +S
Sbjct: 959 ---PLPKSFSSPPSPSNKREEEEEEFNFEV----IPPPPEFSNDPEPPAPALQYLGRQSS 1011
Query: 4928 PPTEPLVELPTEPLAEPPVPSPLPLASSPESAR 4960
PP +L P A P P L + P AR
Sbjct: 1012 PPRNNYSDLRQLPNAGPGAPPALGFSRFPAGAR 1044
Score = 46.6 bits (109), Expect = 7e-04
Identities = 172/778 (22%), Positives = 253/778 (32%), Gaps = 149/778 (19%)
Query: 1955 SRERGGFFSPEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQ 2014
SR F S PG +P + G P P T LS + ++ LG
Sbjct: 481 SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETL------LSLPAKDTPPGVPEKSLGG 534
Query: 2015 LSTISPVLYANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRIN 2074
S ++ P++ DY S + ++ ++ A L A + A I
Sbjct: 535 SSLTETEAAPSLTLPSV--DYIPQDSPTPSVRQIRNELEAR-----LSSAAEKEAKPSIG 587
Query: 2075 KVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAG 2134
+ + + + + G K +P +PPQ L P + P +G P
Sbjct: 588 SLPPKPRLEGGRICENGADDDKLSKPVAK-NLPPQSTTL-LPTTSLQPKAMLGPAIPPKA 645
Query: 2135 LSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLE----PRFP 2190
A PP ++ P +P + L P P + S P PL+ P
Sbjct: 646 TPEPAI----PPKATL-WPATPPKA--TLGPATPLKATS------GPTTPLKATSGPAIA 692
Query: 2191 TAPPTYPPYPS---------PTGAPAQPPMLGASSRP---GAGQPGEFHTTPPGTPRHQP 2238
+ T P S P G P +P S+ G G P E P R
Sbjct: 693 STATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSA 752
Query: 2239 STPDP----------FLKPRC-------------PSL---------DNLAVPESPGV--- 2263
+ P KP C P+L + + V E PG+
Sbjct: 753 AFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAK 812
Query: 2264 --GGGKASEPLLSPPPFGE-----SRKALEVKKEELGASSPSYGPPNLGFVDSPSS-GTH 2315
+ ++ LL P GE S AL + + S G LG P S H
Sbjct: 813 PPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAA-LGRSSLPGSLRDH 871
Query: 2316 LGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSH--PDIFRPGS 2373
E + +F + TP + V P+ P +E L P+ P + R
Sbjct: 872 SHQAEASSDSIFHSQGTPNSFTVVPKLP------KEAEKDSPLTTEIPNKWGPRLGRDAE 925
Query: 2374 YTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAE 2433
T+ + T +P+P P + + P +LP P+S SS SP R E
Sbjct: 926 GTELSRRHNWT-KPEPQAPVAWERVAPSNLPQGH-----PLPKSFSSPPSPSNKREEEEE 979
Query: 2434 AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHK-PPRPQPPEVAF--KAGSLAHTSLG 2490
F + P P +S P P + PPR ++ AG A +LG
Sbjct: 980 EFNFEVIPP----PPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALG 1035
Query: 2491 AGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPP 2550
FPA AG L SG + ++ VGEP P
Sbjct: 1036 FSRFPAGARYAGAGGLERF--SGGGRSLIKKR-----------------LYVGEPHRGPG 1076
Query: 2551 VPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPL 2610
+P G + FGP P G P+ V + P G P G + G +
Sbjct: 1077 LPHGGTGRSLSSPNCFGPQP--GGPEMRR--VNSAGRAPPGGLHAPRLSLEGAARGAAEA 1132
Query: 2611 RPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAEL-PGTQDP 2667
+ + GS Y A+ RS T+ T GS + T + PGT+ P
Sbjct: 1133 KHKA-------PGSADYGFAPAAGRSPYTT---------TRYGSPINTFTVRPGTRHP 1174
Score = 46.2 bits (108), Expect = 9e-04
Identities = 101/438 (23%), Positives = 152/438 (34%), Gaps = 63/438 (14%)
Query: 3980 QSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039
QS TLL P Q + LGP +P K + P TL + T+ PA +AT
Sbjct: 621 QSTTLL-PTTSLQPKAMLGPAIPPKATPEPAIPPK--ATLWPATPPKATLGPATPLKATS 677
Query: 4040 GPST---HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQ-PSSLQLQPPL 4095
GP+T GP AI +T ++ T ++ P QP+ P+S ++ P
Sbjct: 678 GPTTPLKATSGP-AIASTATTLPTTTSQLMAEKDSG-------PAGQPEKPASQEVSTPS 729
Query: 4096 RLPGQ-QQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA----QPSVS---LGDQPGS 4147
+ G+ + + L T G S +S VP L Q S+S P
Sbjct: 730 QARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTL 789
Query: 4148 MTQNLLGPQQPMLER-----PMQNNTGPQP-------PKPGPVLQSGQGLPGVGIMPTVG 4195
GP +P+ + P + QP P G V++ G + +
Sbjct: 790 ARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRA 849
Query: 4196 QLRAQLQGVLAKNP---QLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSP 4252
Q + L ++ LR S Q + ++ + S V P + + SP
Sbjct: 850 QKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTV--VPKLPKEAEKDSP 907
Query: 4253 LQGLLGCQ--PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPP 4310
L + + P+LG + P PQ P V P+
Sbjct: 908 LTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWER-------------VAPSNL 954
Query: 4311 PSSPQEPKRPSQLPSPSSQLPTEAQ--------LPPTHPGTPKPQGPTLEPPPGRVSPAA 4362
P PK S PSPS++ E + PP P+P P L+ + SP
Sbjct: 955 PQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014
Query: 4363 AQLADTLFSKGLGPWDPP 4380
+D GP PP
Sbjct: 1015 NNYSDLRQLPNAGPGAPP 1032
Score = 45.1 bits (105), Expect = 0.002
Identities = 45/145 (31%), Positives = 57/145 (39%), Gaps = 12/145 (8%)
Query: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942
SP P PP+ L PPP +PPP P+ + + P T +PT P
Sbjct: 161 SPLPSPPS------TAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF 214
Query: 4943 EPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGV-RWKRLRLLLTIQKGSG 5001
PP P PL + P P P A P + RL GV +WK L Q +
Sbjct: 215 IPPAP-PLAFLAPPPPPVPAP-APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEAT 272
Query: 5002 RQEDEREVAEFMEQLGTALRPDKVP 5026
R R A E G+AL P+ P
Sbjct: 273 RASPPRSPA---EPKGSALGPNPEP 294
Score = 43.9 bits (102), Expect = 0.004
Identities = 99/457 (21%), Positives = 139/457 (30%), Gaps = 102/457 (22%)
Query: 4293 PGALSTGPVLGPVHPTPPPSSPQ---EPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349
PG ++ P P P P PQ EP S LPSP S P PP P P
Sbjct: 130 PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAP-----PPPPLLLEPPPPP 184
Query: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPE 4409
++ PPP V A + PP L+ P +P P
Sbjct: 185 SMAPPPPPVLEALS---------------PPHTLSSPSIPTPPDFIP-----------PA 218
Query: 4410 ASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRA 4469
+ P P G + PG + +
Sbjct: 219 PPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPG--------------------GVTKW 258
Query: 4470 KNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKED--AAARKPLTPKPKRVQK 4527
K+ GR +E RA + E K N E R P P V+
Sbjct: 259 KSDVALNGRQAEATRA------SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT 312
Query: 4528 ASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLT--------EPAITANFSLFAPF 4579
+S + +++ RKE+G L + P + EP AP
Sbjct: 313 SSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP- 371
Query: 4580 GSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMV 4639
P GQSQ + +G P PP PP + PP PPP+
Sbjct: 372 --ASPRLGQSQSQADERAGTPPPA---------------PPLPPPA-PPLPPPAPPLPPA 413
Query: 4640 NGVTPSEELGEHPKD--AASARDSERALRDTSEVKSLDLLAA---LPTPPHNQTEDVRME 4694
P + HP + + S AL+ S + A+ + +Q E +R E
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNE 473
Query: 4695 --------SDEDSDSPDSIVPASSPESILGEEAPRFP 4723
ED P +P+S G++ PR P
Sbjct: 474 LAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLP 510
Score = 40.4 bits (93), Expect = 0.049
Identities = 44/198 (22%), Positives = 68/198 (34%), Gaps = 40/198 (20%)
Query: 2771 RLSRPPPPATP--SSMDVNSRQLVGGSQAFYQRAPYP---GSLPLQQQQQQLWQQQQATA 2825
R S P PA P S++ N + ++F P P S+P+Q+ Q+ +++ AT
Sbjct: 273 RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332
Query: 2826 ATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQ 2885
R + F P ++ P + P P G + + + + +
Sbjct: 333 KAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS------QSQADER 386
Query: 2886 KGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNS 2945
G P P P PP P PP P+APP P +
Sbjct: 387 AGTPPPAPPLPPPAPPLPPP-----------------------APPLPPAAPPLPCAQKA 423
Query: 2946 LHP------TPHTKGPTL 2957
HP TP + P L
Sbjct: 424 AHPPAGFTKTPKSSSPAL 441
Score = 40.4 bits (93), Expect = 0.049
Identities = 136/636 (21%), Positives = 211/636 (33%), Gaps = 121/636 (19%)
Query: 4048 PLAIGTTPESM--ATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQV 4105
P TP+S A +P PS + V + Q L+ + L G +++
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR 486
Query: 4106 SLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQ 4165
L H G Q G + +P S+ D P + + LG
Sbjct: 487 FLSHRPGPTVAPQSKEGK--KGPRLPEKETLLSLPAKDTPPGVPEKSLGG---------- 534
Query: 4166 NNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAK------NPQLRHLSPQQQ 4219
++ P L S +P P+V Q+R +L+ L+ P + L P+ +
Sbjct: 535 SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPR 594
Query: 4220 QQLQALL---MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQE 4276
+ + + PP T+ LQ P GP
Sbjct: 595 LEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQ------------PKAMLGPAIP 642
Query: 4277 LGAGPRPQGPPRL---PAPPGALSTGPVL------GPVHPTPPPSSPQEPKRPSQLPSPS 4327
A P P PP+ PA P + GP GP P S P + LP+ +
Sbjct: 643 PKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTT 702
Query: 4328 SQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQ 4387
SQL E K GP +P PA+ +++ ++G G L TQ
Sbjct: 703 SQLMAE-----------KDSGPAGQPE----KPASQEVSTPSQARGEGSPSEATRL-PTQ 746
Query: 4388 KPEQSSLVPGHLDQVNGQV----VPEASQLSIKQE--------PREEPCALGAQSVKREA 4435
S+ P G+V P Q S+ +E R G +E
Sbjct: 747 GARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEP 806
Query: 4436 NGEPIGAPGTSNHL--LLAGP-------RSEAGHLLL---QKLLRAKNVQLSTGRGSEGL 4483
G P P ++ LL P R LLL Q+ + ++V + GR S L
Sbjct: 807 PGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSS--L 864
Query: 4484 RAEINGHIDSKLAGLEQ--KLQGTPSN-------KEDAAARKPLTPK------PKRVQKA 4528
+ H A + QGTP++ ++A PLT + P+ + A
Sbjct: 865 PGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDA 924
Query: 4529 SDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQ 4588
+S R K + +A + + S LP P + +FS P N +
Sbjct: 925 EGTELSRRHNWTKPE----PQAPVAWERVAPSNLPQGHP-LPKSFS-----SPPSPSNKR 974
Query: 4589 SQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPS 4624
+ F +P P++ SN P PP+
Sbjct: 975 EEEEEEFNFEVIPPPPEF----------SNDPEPPA 1000
Score = 38.9 bits (89), Expect = 0.14
Identities = 36/114 (31%), Positives = 45/114 (39%), Gaps = 28/114 (24%)
Query: 2867 PVPGPA-GPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLA 2925
P PGPA GP Q I PGG+P P P P P+ +P
Sbjct: 142 PPPGPAPGPPQDISEP--------PGGSPLPSP-PSTAPPPPPLLLEP------------ 180
Query: 2926 VSGLPPQKPSAPPAPELNNSLHPTPHT-KGPTLPTGLELVNRPPSSTELGRPNP 2978
PP APP P + +L P PHT P++PT + + P L P P
Sbjct: 181 ----PPPPSMAPPPPPVLEALSP-PHTLSSPSIPTPPDFIPPAPPLAFLAPPPP 229
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 133 bits (334), Expect = 6e-30
Identities = 255/1018 (25%), Positives = 354/1018 (34%), Gaps = 204/1018 (20%)
Query: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPE 499
L+PPP P PP++ S PP S L PP P P P L P +P PPP
Sbjct: 138 LIPPPPPGPAPGPPQD--ISEPPGGSPLPSPPSTAPPPP-PLLLEPPPPPSMAP-PPPPV 193
Query: 500 ESPLSPPPE-SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP----- 553
LSPP SSP P +PP+ PP+P L PPP +PP SP
Sbjct: 194 LEALSPPHTLSSPSIP------TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT 247
Query: 554 -LSPP-------PEELPTSPPPEASRLSPP-----PEESPMSPPPE------ESPMSPPP 594
L PP + EA+R SPP P+ S + P PE S PPP
Sbjct: 248 RLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307
Query: 595 EASRLFP-PFEESPLSPPPEESPLSPPPEASRLSPP----------PEDSPMSPPPEESP 643
R P +E+ +P EE P L P P+ +P P E
Sbjct: 308 TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELK 367
Query: 644 MSPP--PEVSRLSPLPVVSRLSPPPEESPLSPP----PEESPTSPP-----PEASRLSPP 692
+ P P + + S R PP PL PP P +P PP P A + + P
Sbjct: 368 ATAPASPRLGQ-SQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
Query: 693 P-----EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL-SPR 746
P +SP + P P PE++ S P++ P + + +L R
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD----PSQMEKLRNELAAYLCGSR 482
Query: 747 PEEPHLSPRPEEPHLSPQAEEPHLSPQ-PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805
E+ LS RP P ++PQ++E P+ PE+ L ++P + E E
Sbjct: 483 REDRFLSHRP-GPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETE 541
Query: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
+P P + +P++ SP P + + E S +E+ KP + P
Sbjct: 542 AAPSLTLPSVDYIPQD---SPTPSVRQIRNELEARLSSAAEKEA-------KPSIGSLPP 591
Query: 866 KPPEEPGQC------------PAPEELP-----LFPPPG---EPSLSPLLGEPALSEPGE 905
KP E G+ P + LP L P + L P + A EP
Sbjct: 592 KPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAI 651
Query: 906 PPLSPL----PEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPF 961
PP + L P + L P+ L P PL P I + A + +L
Sbjct: 652 PPKATLWPATPPKATLGPA--TPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEK 709
Query: 962 GAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM------ILPPSPGSPVGPASPI 1015
+ PE P A+ + TP E + ++ +P PP SP G P
Sbjct: 710 DSGPAGQPEKP-ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKT-SPGGGEVPC 767
Query: 1016 LMEPLPPQCS----------PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVS 1065
L +P Q S L + P PP LP P+ P +
Sbjct: 768 LYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQP-------T 820
Query: 1066 DEAELHEMETEKVSEPECPALEPSA---------------TSPLPSPMGDLSCPAPSPAP 1110
DE H + E V AL +A S LP + D S A + +
Sbjct: 821 DELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSD 880
Query: 1111 ALDDFSGLGEDTAPLDGI------DAPGSQPEPGQTPGSLASELKGSPV-----LLDPEE 1159
++ G + + D+P + P + L + +G+ + PE
Sbjct: 881 SIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEP 940
Query: 1160 LAPVTPMEV--------YPECKQTAGQGSPC----EEQEEPRAPVAPTPPTLIKSDIVNE 1207
APV V +P K + SP EE+EE V P PP E
Sbjct: 941 QAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPP---------E 991
Query: 1208 ISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPET 1267
SN DPE LG + P + LR ++ P
Sbjct: 992 FSN--------------------DPEPPAPALQYLGRQSS-PPRNNYSDLRQLPNAGPGA 1030
Query: 1268 DDSLLCDAGTAISGGKAEGEKGRRR-SSPARSRIKQGRSSSFPGRRRPRGGAHGGRGR 1324
+L A G + G G R S RS IK+ P R G HGG GR
Sbjct: 1031 PPALGFSRFPA--GARYAGAGGLERFSGGGRSLIKKRLYVGEP--HRGPGLPHGGTGR 1084
Score = 83.2 bits (204), Expect = 7e-15
Identities = 240/1010 (23%), Positives = 322/1010 (31%), Gaps = 213/1010 (21%)
Query: 2066 DNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIF 2125
D+ A + + + VGD+ L + PP A G P + P
Sbjct: 101 DDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEP--- 157
Query: 2126 IGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPF--GLAPAY 2183
P G P S P P L PP P+ P P L+P +
Sbjct: 158 ------PGG----------SPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201
Query: 2184 PL-EPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTT--PPGTPRHQPST 2240
L P PT P PP P PP + A + P P T PPG S
Sbjct: 202 TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKS- 260
Query: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKA----SEPLLS-------PPPFG------ESRK 2283
D L R + P SP G A EP L+ PPP ++
Sbjct: 261 -DVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQE 319
Query: 2284 ALEVKKEELGAS--SPSYGPPNLGFVDSPSSGTHLG-GLELKTPDVFK--APLTPRASQV 2338
A E ++E GA+ +PS P F P+S + E P K AP +PR Q
Sbjct: 320 AQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS 379
Query: 2339 EPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCAL 2398
+ Q+ R PPPA P PP P + P PPL P P P A
Sbjct: 380 QSQADE---RAGTPPPA---PPLPPPAPPL--------PPPAPPLPPAAPPLPCAQKAAH 425
Query: 2399 PPRSLPSDPFSRVPA--------SPQSQSSSQSPLTPRPLS---------AEAFCPSPVT 2441
PP P S PA SP++ +SS +P+ R S A C S
Sbjct: 426 PPAGFTKTPKSSSPALKPKPNPPSPENTASS-APVDWRDPSQMEKLRNELAAYLCGSRRE 484
Query: 2442 PRFQS--PDPYSRPPSRPQSRDPFAP-----LHKPPRPQPPEVAFKA---GSLAHTSL-- 2489
RF S P P P S+ + P P L P + PP V K+ SL T
Sbjct: 485 DRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAP 544
Query: 2490 -----GAGGFPAALPA--------------GPAGELHAKVPSGQPPNFVRSPG-----TG 2525
P P A E AK G P R G G
Sbjct: 545 SLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENG 604
Query: 2526 A---------------FVGTPSPMRFTFPQAVGEPSLKP-PVPQPGLPPPHGINSHFGPG 2569
A T P P+A+ P++ P P+P +PP + P
Sbjct: 605 ADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPK 664
Query: 2570 PTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSP---LRPPSVLPPPAPDGSLP 2626
TLG +T +G P + GP+ ST + + + P P+
Sbjct: 665 ATLG--PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPAS 722
Query: 2627 YLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRL 2686
SQ G SP E P G SS A P PG + Q
Sbjct: 723 QEVSTPSQARGEGSPSEATRLPTQGARSS---AAFPPKTSPGGGEVPCLYKPHCHQSSLS 779
Query: 2687 RELLIRQQIQRNTLRQEKETAAAAAGAVGP--PGSWGAEPSSPAFEQLSRGQTPFAGTQD 2744
RE+ + A GA GP P P PA P A Q
Sbjct: 780 REVAVVM------------PTLARGGAAGPGEPVEVKEPPGLPA--------KPPASAQP 819
Query: 2745 KSSLVGLPPSKLSGPILGPGS-----FPSDDRLSRPPP-------PATPSSMDVNSRQLV 2792
L+ P ++G ++ GS + R + + P S+ +S Q
Sbjct: 820 TDELLRHP---VTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAE 876
Query: 2793 GGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGS 2852
S + + P S + + + ++ ++ P+ GP LGR A G+
Sbjct: 877 ASSDSIFHSQGTPNSFTVVPKLPKEAEKDS---------PLTTEIPNKWGPRLGRDAEGT 927
Query: 2853 PLA-GISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTP----------FPGQGPP 2901
L+ + P P PV + H + K +P F + P
Sbjct: 928 ELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIP 987
Query: 2902 QRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQK------------PSAPPA 2939
P F S DP AP L+ L PP+ P APPA
Sbjct: 988 PPPEF---SNDPEPPAP-ALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPA 1033
Score = 66.2 bits (160), Expect = 8e-10
Identities = 123/451 (27%), Positives = 168/451 (37%), Gaps = 102/451 (22%)
Query: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
PGQ ++L + PPP P+ P +SEP P SPLP SP PS +P
Sbjct: 130 PGQYG--QDLLIPPPPPGPAPGP---PQDISEP--PGGSPLP-----SP---PSTAP--- 171
Query: 931 PPDPL--PPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETP---ISP- 984
PP PL PP P + PP L L P L++P + TP I P
Sbjct: 172 PPPPLLLEPPPPPSMAPPPPPVLEAL-------------SPPHTLSSPSIPTPPDFIPPA 218
Query: 985 PPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH--SLVPQNSPPSQC 1042
PP A P P P PP+P SP + + PP + +L + + ++
Sbjct: 219 PPLAFLAPPPPPVPAPAPPAPASPHTVGTRL----FPPGGVTKWKSDVALNGRQAEATRA 274
Query: 1043 SPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEP--------------ECPALEP 1088
SPP SP P G +G + E L + KV P E P E
Sbjct: 275 SPPR------SPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEE 328
Query: 1089 SATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPG-------SQPEPGQTP 1141
AT PS + P P P+ + S + D AP D PG + P GQ+
Sbjct: 329 GATKKAPSRL-----PLP-PSFHIRPASQVYPDRAPEP--DCPGELKATAPASPRLGQSQ 380
Query: 1142 GSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIK 1201
S A E G+P P L P P P P P AP P K
Sbjct: 381 -SQADERAGTPPPAPP--LPPPAP---------------PLPPPAPPLPPAAPPLPCAQK 422
Query: 1202 SDIVNEISNLSQGDASASFPGSEPLLGSPDPEG-GGSLSMELGVSTDVSPARDEGSLRLC 1260
+ + + ++ S+S P +P P PE S ++ + + R+E + LC
Sbjct: 423 A--AHPPAGFTKTPKSSS-PALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLC 479
Query: 1261 TDSLPETDDSLLCDAGTAISGGKAEGEKGRR 1291
D L G ++ EG+KG R
Sbjct: 480 GSR--REDRFLSHRPGPTVAPQSKEGKKGPR 508
Score = 63.2 bits (152), Expect = 7e-09
Identities = 118/499 (23%), Positives = 167/499 (33%), Gaps = 104/499 (20%)
Query: 4534 SSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRG 4593
S L+ VR L QE L + P++ +F+ G+ VNG +L
Sbjct: 64 SGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYS 123
Query: 4594 AFGSGALPTGPDYYSQLLT------------KNNLSNPP------TPPSSLPPTPPPSVQ 4635
+ G P Y Q L ++S PP +PPS+ PP PP ++
Sbjct: 124 SVGD----LRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLE 179
Query: 4636 QKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMES 4695
P + P A L S D + P PP + +
Sbjct: 180 PP------PPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP--PAPP------LAFLA 225
Query: 4696 DEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDT 4755
P PA + +G FP G +W+ D AL+ RAS P P
Sbjct: 226 PPPPPVPAPAPPAPASPHTVGTRL--FPPGGVTKWKS-DVALNGRQAEATRASPPRSPAE 282
Query: 4756 KPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSY 4815
ALG P P T+ + S K+P
Sbjct: 283 PKGSALG---PNPEPHLTFPR-------------------------------SFKVP--- 305
Query: 4816 EVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDI 4875
P +P R + P + E P KE+G K+P P + P + ++ +
Sbjct: 306 ----PPTPVRTSSIPVQEAQEAPR-KEEGATKKAPSRLP--------LPPSFHIRPASQV 352
Query: 4876 LSLLKQESPAPEPPTQHSYTYNVS-NLDVRQLSA------PPPEEPSPPPSPLAPSPASP 4928
+P P+ P + T S L Q A PPP P PPP+P P PA P
Sbjct: 353 YP---DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP 409
Query: 4929 PTEPLVELP-TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKG-VR 4986
LP + A PP SS + +PKP PE S P W+ +
Sbjct: 410 LPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAP---VDWRDPSQ 466
Query: 4987 WKRLRLLLTIQKGSGRQED 5005
++LR L R+ED
Sbjct: 467 MEKLRNELAAYLCGSRRED 485
Score = 58.9 bits (141), Expect = 1e-07
Identities = 167/769 (21%), Positives = 247/769 (32%), Gaps = 98/769 (12%)
Query: 4267 PGPQTGPLQEL----GAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPP----------- 4311
PGP GP Q++ G P P P P PP L P + P PPP
Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTL 203
Query: 4312 SSPQEPKRPSQLPSPSSQLPTEAQLPP--THPGTPKPQGP----TLEPPPGRVSPAAAQL 4365
SSP P P +P P+ L A PP P P P P T PPG V+ + +
Sbjct: 204 SSPSIPTPPDFIP-PAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDV 262
Query: 4366 ADTLFSKGLGPWDPPDNLAETQKPEQSSLVPG---HLDQVNGQVVPEASQLSIKQEPREE 4422
A PP + AE P+ S+L P HL VP + + P +E
Sbjct: 263 ALNGRQAEATRASPPRSPAE---PKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQE 319
Query: 4423 PCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEG 4482
AQ R+ G AP P + H+ + G
Sbjct: 320 -----AQEAPRKEEGATKKAPSRL-------PLPPSFHIRPASQVYPDRAPEPDCPGELK 367
Query: 4483 LRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKE 4542
A + + + +++ P PL P + A+ L ++K
Sbjct: 368 ATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPP 427
Query: 4543 DGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPT 4602
G + +L P P N + AP P + +LR A
Sbjct: 428 AGFTKTPK-----SSSPALKPKPNPPSPENTASSAPVDWRDP-SQMEKLRNEL--AAYLC 479
Query: 4603 GPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSE 4662
G + L ++ P P S P + +K P+++ P
Sbjct: 480 GSRREDRFL--SHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDT---PPGVPEKSLGG 534
Query: 4663 RALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRF 4722
+L +T SL L + P + T VR +E S + SI G P+
Sbjct: 535 SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSI-GSLPPK- 592
Query: 4723 PHLGSGR----WEQEDRALSPVIPLIPRASIPVFPDT--KPYGALGLEVPGKL------- 4769
P L GR +D+ PV +P S + P T +P LG +P K
Sbjct: 593 PRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIP 652
Query: 4770 ----------------PVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPN 4813
P T + G + T A A + ++L++ K +
Sbjct: 653 PKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEK--D 710
Query: 4814 SYEVLFPESPA-RAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQ 4872
S PE PA + + P + EG + L P + A P T
Sbjct: 711 SGPAGQPEKPASQEVSTPSQARGEGSPSEATRL--------PTQGARSSAAFPPKTSPGG 762
Query: 4873 LDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEP 4932
++ L K + + P E PP P P ++ PT+
Sbjct: 763 GEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDE 822
Query: 4933 LVELP-TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLK 4980
L+ P T + E P L LA+ + K R+ G S P L+
Sbjct: 823 LLRHPVTGEVVERGSPMALLLAARQRA--QKGRSVGAALGRSSLPGSLR 869
Score = 57.0 bits (136), Expect = 5e-07
Identities = 212/933 (22%), Positives = 289/933 (30%), Gaps = 181/933 (19%)
Query: 4126 EASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGL 4185
EA S PH L+ PS+ T P P P+ P PP P P
Sbjct: 195 EALSPPHTLSSPSIP--------TPPDFIPPAP----PLAFLAPPPPPVPAPAP------ 236
Query: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245
P TVG GV + + L RQ + ++A P +
Sbjct: 237 PAPASPHTVGTRLFPPGGVT-------------KWKSDVALNGRQAEATRASPPRSPAEP 283
Query: 4246 PGTQTSPLQGLLGCQPQLGGFPGP-----QTGPLQELGAGPRPQ------GPPRLPAPPG 4294
G+ P P+ P P + P+QE PR + P RLP PP
Sbjct: 284 KGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP- 342
Query: 4295 ALSTGPVLGPVHP--TPPPSSPQEPKRPS----QLPSPSSQLPTEAQLPPTHPGTPKPQG 4348
+ P V+P P P P E K + +L SQ A PP P P P
Sbjct: 343 SFHIRPA-SQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPP-A 400
Query: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVP 4408
P L PP + PAA L + PP +T K +L P
Sbjct: 401 PPLPPPAPPLPPAAPPLPCAQKAA-----HPPAGFTKTPKSSSPALKPK----------- 444
Query: 4409 EASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLL--LAGPRSEAGHLLLQKL 4466
P E A A R+ P N L L G R E L +
Sbjct: 445 -------PNPPSPENTASSAPVDWRD----PSQMEKLRNELAAYLCGSRREDRFLSHRP- 492
Query: 4467 LRAKNVQLSTGRGSEGLRAEINGHIDSKLA-----GLEQKLQGTPSNKEDAAARKPLTPK 4521
V + G +G R + S A G+ +K G S E AA P
Sbjct: 493 --GPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPS 550
Query: 4522 PKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLP----LTEPAITANFS--- 4574
+ + D S +++R E R S A K+ K + LP L I N +
Sbjct: 551 VDYIPQ--DSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDD 608
Query: 4575 -LFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSL--PPTPP 4631
L P P + L GP + P PP + P TPP
Sbjct: 609 KLSKPVAKNLPPQSTTLLPTTSLQPKAMLGP-----AIPPKATPEPAIPPKATLWPATPP 663
Query: 4632 -----PSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHN 4686
P+ K +G T + P A++A K P
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQ 723
Query: 4687 QTEDVRMESDEDSDSPDSIVPASSPESIL---------GEEAPRF--PHLGSGRWEQEDR 4735
+ E S S + +P S G E P PH +E
Sbjct: 724 EVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE-- 781
Query: 4736 ALSPVIPLIPRASI------------PVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVS 4783
++ V+P + R P P P A + + PVT +GS ++
Sbjct: 782 -VAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
Query: 4784 VMLTVSAAAAKNLN-GVMVAVAELL-------------------SMKIPNSYEVLFPESP 4823
++L A K + G + + L S PNS+ V+ P+ P
Sbjct: 841 LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV-PKLP 899
Query: 4824 ARAGTE-PKKGEAEGPGGKEKG--LEGKSPDTGPDWLKQ-------FDAVLPGYTLKSQL 4873
A + P E G G EG +W K ++ V P +
Sbjct: 900 KEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGH- 958
Query: 4874 DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS------PAS 4927
L K S P P + N +V PPP E S P P AP+ +S
Sbjct: 959 ---PLPKSFSSPPSPSNKREEEEEEFNFEV----IPPPPEFSNDPEPPAPALQYLGRQSS 1011
Query: 4928 PPTEPLVELPTEPLAEPPVPSPLPLASSPESAR 4960
PP +L P A P P L + P AR
Sbjct: 1012 PPRNNYSDLRQLPNAGPGAPPALGFSRFPAGAR 1044
Score = 46.6 bits (109), Expect = 7e-04
Identities = 172/778 (22%), Positives = 253/778 (32%), Gaps = 149/778 (19%)
Query: 1955 SRERGGFFSPEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQ 2014
SR F S PG +P + G P P T LS + ++ LG
Sbjct: 481 SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETL------LSLPAKDTPPGVPEKSLGG 534
Query: 2015 LSTISPVLYANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRIN 2074
S ++ P++ DY S + ++ ++ A L A + A I
Sbjct: 535 SSLTETEAAPSLTLPSV--DYIPQDSPTPSVRQIRNELEAR-----LSSAAEKEAKPSIG 587
Query: 2075 KVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAG 2134
+ + + + + G K +P +PPQ L P + P +G P
Sbjct: 588 SLPPKPRLEGGRICENGADDDKLSKPVAK-NLPPQSTTL-LPTTSLQPKAMLGPAIPPKA 645
Query: 2135 LSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLE----PRFP 2190
A PP ++ P +P + L P P + S P PL+ P
Sbjct: 646 TPEPAI----PPKATL-WPATPPKA--TLGPATPLKATS------GPTTPLKATSGPAIA 692
Query: 2191 TAPPTYPPYPS---------PTGAPAQPPMLGASSRP---GAGQPGEFHTTPPGTPRHQP 2238
+ T P S P G P +P S+ G G P E P R
Sbjct: 693 STATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSA 752
Query: 2239 STPDP----------FLKPRC-------------PSL---------DNLAVPESPGV--- 2263
+ P KP C P+L + + V E PG+
Sbjct: 753 AFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAK 812
Query: 2264 --GGGKASEPLLSPPPFGE-----SRKALEVKKEELGASSPSYGPPNLGFVDSPSS-GTH 2315
+ ++ LL P GE S AL + + S G LG P S H
Sbjct: 813 PPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAA-LGRSSLPGSLRDH 871
Query: 2316 LGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSH--PDIFRPGS 2373
E + +F + TP + V P+ P +E L P+ P + R
Sbjct: 872 SHQAEASSDSIFHSQGTPNSFTVVPKLP------KEAEKDSPLTTEIPNKWGPRLGRDAE 925
Query: 2374 YTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAE 2433
T+ + T +P+P P + + P +LP P+S SS SP R E
Sbjct: 926 GTELSRRHNWT-KPEPQAPVAWERVAPSNLPQGH-----PLPKSFSSPPSPSNKREEEEE 979
Query: 2434 AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHK-PPRPQPPEVAF--KAGSLAHTSLG 2490
F + P P +S P P + PPR ++ AG A +LG
Sbjct: 980 EFNFEVIPP----PPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALG 1035
Query: 2491 AGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPP 2550
FPA AG L SG + ++ VGEP P
Sbjct: 1036 FSRFPAGARYAGAGGLERF--SGGGRSLIKKR-----------------LYVGEPHRGPG 1076
Query: 2551 VPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPL 2610
+P G + FGP P G P+ V + P G P G + G +
Sbjct: 1077 LPHGGTGRSLSSPNCFGPQP--GGPEMRR--VNSAGRAPPGGLHAPRLSLEGAARGAAEA 1132
Query: 2611 RPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAEL-PGTQDP 2667
+ + GS Y A+ RS T+ T GS + T + PGT+ P
Sbjct: 1133 KHKA-------PGSADYGFAPAAGRSPYTT---------TRYGSPINTFTVRPGTRHP 1174
Score = 46.2 bits (108), Expect = 9e-04
Identities = 101/438 (23%), Positives = 152/438 (34%), Gaps = 63/438 (14%)
Query: 3980 QSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039
QS TLL P Q + LGP +P K + P TL + T+ PA +AT
Sbjct: 621 QSTTLL-PTTSLQPKAMLGPAIPPKATPEPAIPPK--ATLWPATPPKATLGPATPLKATS 677
Query: 4040 GPST---HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQ-PSSLQLQPPL 4095
GP+T GP AI +T ++ T ++ P QP+ P+S ++ P
Sbjct: 678 GPTTPLKATSGP-AIASTATTLPTTTSQLMAEKDSG-------PAGQPEKPASQEVSTPS 729
Query: 4096 RLPGQ-QQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA----QPSVS---LGDQPGS 4147
+ G+ + + L T G S +S VP L Q S+S P
Sbjct: 730 QARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTL 789
Query: 4148 MTQNLLGPQQPMLER-----PMQNNTGPQP-------PKPGPVLQSGQGLPGVGIMPTVG 4195
GP +P+ + P + QP P G V++ G + +
Sbjct: 790 ARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRA 849
Query: 4196 QLRAQLQGVLAKNP---QLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSP 4252
Q + L ++ LR S Q + ++ + S V P + + SP
Sbjct: 850 QKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTV--VPKLPKEAEKDSP 907
Query: 4253 LQGLLGCQ--PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPP 4310
L + + P+LG + P PQ P V P+
Sbjct: 908 LTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWER-------------VAPSNL 954
Query: 4311 PSSPQEPKRPSQLPSPSSQLPTEAQ--------LPPTHPGTPKPQGPTLEPPPGRVSPAA 4362
P PK S PSPS++ E + PP P+P P L+ + SP
Sbjct: 955 PQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014
Query: 4363 AQLADTLFSKGLGPWDPP 4380
+D GP PP
Sbjct: 1015 NNYSDLRQLPNAGPGAPP 1032
Score = 45.1 bits (105), Expect = 0.002
Identities = 45/145 (31%), Positives = 57/145 (39%), Gaps = 12/145 (8%)
Query: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942
SP P PP+ L PPP +PPP P+ + + P T +PT P
Sbjct: 161 SPLPSPPS------TAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF 214
Query: 4943 EPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGV-RWKRLRLLLTIQKGSG 5001
PP P PL + P P P A P + RL GV +WK L Q +
Sbjct: 215 IPPAP-PLAFLAPPPPPVPAP-APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEAT 272
Query: 5002 RQEDEREVAEFMEQLGTALRPDKVP 5026
R R A E G+AL P+ P
Sbjct: 273 RASPPRSPA---EPKGSALGPNPEP 294
Score = 43.9 bits (102), Expect = 0.004
Identities = 99/457 (21%), Positives = 139/457 (30%), Gaps = 102/457 (22%)
Query: 4293 PGALSTGPVLGPVHPTPPPSSPQ---EPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349
PG ++ P P P P PQ EP S LPSP S P PP P P
Sbjct: 130 PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAP-----PPPPLLLEPPPPP 184
Query: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPE 4409
++ PPP V A + PP L+ P +P P
Sbjct: 185 SMAPPPPPVLEALS---------------PPHTLSSPSIPTPPDFIP-----------PA 218
Query: 4410 ASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRA 4469
+ P P G + PG + +
Sbjct: 219 PPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPG--------------------GVTKW 258
Query: 4470 KNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKED--AAARKPLTPKPKRVQK 4527
K+ GR +E RA + E K N E R P P V+
Sbjct: 259 KSDVALNGRQAEATRA------SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT 312
Query: 4528 ASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLT--------EPAITANFSLFAPF 4579
+S + +++ RKE+G L + P + EP AP
Sbjct: 313 SSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP- 371
Query: 4580 GSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMV 4639
P GQSQ + +G P PP PP + PP PPP+
Sbjct: 372 --ASPRLGQSQSQADERAGTPPPA---------------PPLPPPA-PPLPPPAPPLPPA 413
Query: 4640 NGVTPSEELGEHPKD--AASARDSERALRDTSEVKSLDLLAA---LPTPPHNQTEDVRME 4694
P + HP + + S AL+ S + A+ + +Q E +R E
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNE 473
Query: 4695 --------SDEDSDSPDSIVPASSPESILGEEAPRFP 4723
ED P +P+S G++ PR P
Sbjct: 474 LAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLP 510
Score = 40.4 bits (93), Expect = 0.049
Identities = 44/198 (22%), Positives = 68/198 (34%), Gaps = 40/198 (20%)
Query: 2771 RLSRPPPPATP--SSMDVNSRQLVGGSQAFYQRAPYP---GSLPLQQQQQQLWQQQQATA 2825
R S P PA P S++ N + ++F P P S+P+Q+ Q+ +++ AT
Sbjct: 273 RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332
Query: 2826 ATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQ 2885
R + F P ++ P + P P G + + + + +
Sbjct: 333 KAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS------QSQADER 386
Query: 2886 KGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNS 2945
G P P P PP P PP P+APP P +
Sbjct: 387 AGTPPPAPPLPPPAPPLPPP-----------------------APPLPPAAPPLPCAQKA 423
Query: 2946 LHP------TPHTKGPTL 2957
HP TP + P L
Sbjct: 424 AHPPAGFTKTPKSSSPAL 441
Score = 40.4 bits (93), Expect = 0.049
Identities = 136/636 (21%), Positives = 211/636 (33%), Gaps = 121/636 (19%)
Query: 4048 PLAIGTTPESM--ATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQV 4105
P TP+S A +P PS + V + Q L+ + L G +++
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR 486
Query: 4106 SLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQ 4165
L H G Q G + +P S+ D P + + LG
Sbjct: 487 FLSHRPGPTVAPQSKEGK--KGPRLPEKETLLSLPAKDTPPGVPEKSLGG---------- 534
Query: 4166 NNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAK------NPQLRHLSPQQQ 4219
++ P L S +P P+V Q+R +L+ L+ P + L P+ +
Sbjct: 535 SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPR 594
Query: 4220 QQLQALL---MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQE 4276
+ + + PP T+ LQ P GP
Sbjct: 595 LEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQ------------PKAMLGPAIP 642
Query: 4277 LGAGPRPQGPPRL---PAPPGALSTGPVL------GPVHPTPPPSSPQEPKRPSQLPSPS 4327
A P P PP+ PA P + GP GP P S P + LP+ +
Sbjct: 643 PKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTT 702
Query: 4328 SQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQ 4387
SQL E K GP +P PA+ +++ ++G G L TQ
Sbjct: 703 SQLMAE-----------KDSGPAGQPE----KPASQEVSTPSQARGEGSPSEATRL-PTQ 746
Query: 4388 KPEQSSLVPGHLDQVNGQV----VPEASQLSIKQE--------PREEPCALGAQSVKREA 4435
S+ P G+V P Q S+ +E R G +E
Sbjct: 747 GARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEP 806
Query: 4436 NGEPIGAPGTSNHL--LLAGP-------RSEAGHLLL---QKLLRAKNVQLSTGRGSEGL 4483
G P P ++ LL P R LLL Q+ + ++V + GR S L
Sbjct: 807 PGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSS--L 864
Query: 4484 RAEINGHIDSKLAGLEQ--KLQGTPSN-------KEDAAARKPLTPK------PKRVQKA 4528
+ H A + QGTP++ ++A PLT + P+ + A
Sbjct: 865 PGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDA 924
Query: 4529 SDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQ 4588
+S R K + +A + + S LP P + +FS P N +
Sbjct: 925 EGTELSRRHNWTKPE----PQAPVAWERVAPSNLPQGHP-LPKSFS-----SPPSPSNKR 974
Query: 4589 SQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPS 4624
+ F +P P++ SN P PP+
Sbjct: 975 EEEEEEFNFEVIPPPPEF----------SNDPEPPA 1000
Score = 38.9 bits (89), Expect = 0.14
Identities = 36/114 (31%), Positives = 45/114 (39%), Gaps = 28/114 (24%)
Query: 2867 PVPGPA-GPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLA 2925
P PGPA GP Q I PGG+P P P P P+ +P
Sbjct: 142 PPPGPAPGPPQDISEP--------PGGSPLPSP-PSTAPPPPPLLLEP------------ 180
Query: 2926 VSGLPPQKPSAPPAPELNNSLHPTPHT-KGPTLPTGLELVNRPPSSTELGRPNP 2978
PP APP P + +L P PHT P++PT + + P L P P
Sbjct: 181 ----PPPPSMAPPPPPVLEALSP-PHTLSSPSIPTPPDFIPPAPPLAFLAPPPP 229
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
Length = 1188
Score = 133 bits (334), Expect = 6e-30
Identities = 255/1018 (25%), Positives = 354/1018 (34%), Gaps = 204/1018 (20%)
Query: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPE 499
L+PPP P PP++ S PP S L PP P P P L P +P PPP
Sbjct: 138 LIPPPPPGPAPGPPQD--ISEPPGGSPLPSPPSTAPPPP-PLLLEPPPPPSMAP-PPPPV 193
Query: 500 ESPLSPPPE-SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP----- 553
LSPP SSP P +PP+ PP+P L PPP +PP SP
Sbjct: 194 LEALSPPHTLSSPSIP------TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT 247
Query: 554 -LSPP-------PEELPTSPPPEASRLSPP-----PEESPMSPPPE------ESPMSPPP 594
L PP + EA+R SPP P+ S + P PE S PPP
Sbjct: 248 RLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307
Query: 595 EASRLFP-PFEESPLSPPPEESPLSPPPEASRLSPP----------PEDSPMSPPPEESP 643
R P +E+ +P EE P L P P+ +P P E
Sbjct: 308 TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELK 367
Query: 644 MSPP--PEVSRLSPLPVVSRLSPPPEESPLSPP----PEESPTSPP-----PEASRLSPP 692
+ P P + + S R PP PL PP P +P PP P A + + P
Sbjct: 368 ATAPASPRLGQ-SQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
Query: 693 P-----EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL-SPR 746
P +SP + P P PE++ S P++ P + + +L R
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD----PSQMEKLRNELAAYLCGSR 482
Query: 747 PEEPHLSPRPEEPHLSPQAEEPHLSPQ-PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805
E+ LS RP P ++PQ++E P+ PE+ L ++P + E E
Sbjct: 483 REDRFLSHRP-GPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETE 541
Query: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
+P P + +P++ SP P + + E S +E+ KP + P
Sbjct: 542 AAPSLTLPSVDYIPQD---SPTPSVRQIRNELEARLSSAAEKEA-------KPSIGSLPP 591
Query: 866 KPPEEPGQC------------PAPEELP-----LFPPPG---EPSLSPLLGEPALSEPGE 905
KP E G+ P + LP L P + L P + A EP
Sbjct: 592 KPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAI 651
Query: 906 PPLSPL----PEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPF 961
PP + L P + L P+ L P PL P I + A + +L
Sbjct: 652 PPKATLWPATPPKATLGPA--TPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEK 709
Query: 962 GAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM------ILPPSPGSPVGPASPI 1015
+ PE P A+ + TP E + ++ +P PP SP G P
Sbjct: 710 DSGPAGQPEKP-ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKT-SPGGGEVPC 767
Query: 1016 LMEPLPPQCS----------PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVS 1065
L +P Q S L + P PP LP P+ P +
Sbjct: 768 LYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQP-------T 820
Query: 1066 DEAELHEMETEKVSEPECPALEPSA---------------TSPLPSPMGDLSCPAPSPAP 1110
DE H + E V AL +A S LP + D S A + +
Sbjct: 821 DELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSD 880
Query: 1111 ALDDFSGLGEDTAPLDGI------DAPGSQPEPGQTPGSLASELKGSPV-----LLDPEE 1159
++ G + + D+P + P + L + +G+ + PE
Sbjct: 881 SIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEP 940
Query: 1160 LAPVTPMEV--------YPECKQTAGQGSPC----EEQEEPRAPVAPTPPTLIKSDIVNE 1207
APV V +P K + SP EE+EE V P PP E
Sbjct: 941 QAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPP---------E 991
Query: 1208 ISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPET 1267
SN DPE LG + P + LR ++ P
Sbjct: 992 FSN--------------------DPEPPAPALQYLGRQSS-PPRNNYSDLRQLPNAGPGA 1030
Query: 1268 DDSLLCDAGTAISGGKAEGEKGRRR-SSPARSRIKQGRSSSFPGRRRPRGGAHGGRGR 1324
+L A G + G G R S RS IK+ P R G HGG GR
Sbjct: 1031 PPALGFSRFPA--GARYAGAGGLERFSGGGRSLIKKRLYVGEP--HRGPGLPHGGTGR 1084
Score = 83.2 bits (204), Expect = 7e-15
Identities = 240/1010 (23%), Positives = 322/1010 (31%), Gaps = 213/1010 (21%)
Query: 2066 DNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIF 2125
D+ A + + + VGD+ L + PP A G P + P
Sbjct: 101 DDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEP--- 157
Query: 2126 IGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPF--GLAPAY 2183
P G P S P P L PP P+ P P L+P +
Sbjct: 158 ------PGG----------SPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201
Query: 2184 PL-EPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTT--PPGTPRHQPST 2240
L P PT P PP P PP + A + P P T PPG S
Sbjct: 202 TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKS- 260
Query: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKA----SEPLLS-------PPPFG------ESRK 2283
D L R + P SP G A EP L+ PPP ++
Sbjct: 261 -DVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQE 319
Query: 2284 ALEVKKEELGAS--SPSYGPPNLGFVDSPSSGTHLG-GLELKTPDVFK--APLTPRASQV 2338
A E ++E GA+ +PS P F P+S + E P K AP +PR Q
Sbjct: 320 AQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS 379
Query: 2339 EPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCAL 2398
+ Q+ R PPPA P PP P + P PPL P P P A
Sbjct: 380 QSQADE---RAGTPPPA---PPLPPPAPPL--------PPPAPPLPPAAPPLPCAQKAAH 425
Query: 2399 PPRSLPSDPFSRVPA--------SPQSQSSSQSPLTPRPLS---------AEAFCPSPVT 2441
PP P S PA SP++ +SS +P+ R S A C S
Sbjct: 426 PPAGFTKTPKSSSPALKPKPNPPSPENTASS-APVDWRDPSQMEKLRNELAAYLCGSRRE 484
Query: 2442 PRFQS--PDPYSRPPSRPQSRDPFAP-----LHKPPRPQPPEVAFKA---GSLAHTSL-- 2489
RF S P P P S+ + P P L P + PP V K+ SL T
Sbjct: 485 DRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAP 544
Query: 2490 -----GAGGFPAALPA--------------GPAGELHAKVPSGQPPNFVRSPG-----TG 2525
P P A E AK G P R G G
Sbjct: 545 SLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENG 604
Query: 2526 A---------------FVGTPSPMRFTFPQAVGEPSLKP-PVPQPGLPPPHGINSHFGPG 2569
A T P P+A+ P++ P P+P +PP + P
Sbjct: 605 ADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPK 664
Query: 2570 PTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSP---LRPPSVLPPPAPDGSLP 2626
TLG +T +G P + GP+ ST + + + P P+
Sbjct: 665 ATLG--PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPAS 722
Query: 2627 YLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRL 2686
SQ G SP E P G SS A P PG + Q
Sbjct: 723 QEVSTPSQARGEGSPSEATRLPTQGARSS---AAFPPKTSPGGGEVPCLYKPHCHQSSLS 779
Query: 2687 RELLIRQQIQRNTLRQEKETAAAAAGAVGP--PGSWGAEPSSPAFEQLSRGQTPFAGTQD 2744
RE+ + A GA GP P P PA P A Q
Sbjct: 780 REVAVVM------------PTLARGGAAGPGEPVEVKEPPGLPA--------KPPASAQP 819
Query: 2745 KSSLVGLPPSKLSGPILGPGS-----FPSDDRLSRPPP-------PATPSSMDVNSRQLV 2792
L+ P ++G ++ GS + R + + P S+ +S Q
Sbjct: 820 TDELLRHP---VTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAE 876
Query: 2793 GGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGS 2852
S + + P S + + + ++ ++ P+ GP LGR A G+
Sbjct: 877 ASSDSIFHSQGTPNSFTVVPKLPKEAEKDS---------PLTTEIPNKWGPRLGRDAEGT 927
Query: 2853 PLA-GISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTP----------FPGQGPP 2901
L+ + P P PV + H + K +P F + P
Sbjct: 928 ELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIP 987
Query: 2902 QRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQK------------PSAPPA 2939
P F S DP AP L+ L PP+ P APPA
Sbjct: 988 PPPEF---SNDPEPPAP-ALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPA 1033
Score = 66.2 bits (160), Expect = 8e-10
Identities = 123/451 (27%), Positives = 168/451 (37%), Gaps = 102/451 (22%)
Query: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
PGQ ++L + PPP P+ P +SEP P SPLP SP PS +P
Sbjct: 130 PGQYG--QDLLIPPPPPGPAPGP---PQDISEP--PGGSPLP-----SP---PSTAP--- 171
Query: 931 PPDPL--PPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETP---ISP- 984
PP PL PP P + PP L L P L++P + TP I P
Sbjct: 172 PPPPLLLEPPPPPSMAPPPPPVLEAL-------------SPPHTLSSPSIPTPPDFIPPA 218
Query: 985 PPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH--SLVPQNSPPSQC 1042
PP A P P P PP+P SP + + PP + +L + + ++
Sbjct: 219 PPLAFLAPPPPPVPAPAPPAPASPHTVGTRL----FPPGGVTKWKSDVALNGRQAEATRA 274
Query: 1043 SPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEP--------------ECPALEP 1088
SPP SP P G +G + E L + KV P E P E
Sbjct: 275 SPPR------SPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEE 328
Query: 1089 SATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPG-------SQPEPGQTP 1141
AT PS + P P P+ + S + D AP D PG + P GQ+
Sbjct: 329 GATKKAPSRL-----PLP-PSFHIRPASQVYPDRAPEP--DCPGELKATAPASPRLGQSQ 380
Query: 1142 GSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIK 1201
S A E G+P P L P P P P P AP P K
Sbjct: 381 -SQADERAGTPPPAPP--LPPPAP---------------PLPPPAPPLPPAAPPLPCAQK 422
Query: 1202 SDIVNEISNLSQGDASASFPGSEPLLGSPDPEG-GGSLSMELGVSTDVSPARDEGSLRLC 1260
+ + + ++ S+S P +P P PE S ++ + + R+E + LC
Sbjct: 423 A--AHPPAGFTKTPKSSS-PALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLC 479
Query: 1261 TDSLPETDDSLLCDAGTAISGGKAEGEKGRR 1291
D L G ++ EG+KG R
Sbjct: 480 GSR--REDRFLSHRPGPTVAPQSKEGKKGPR 508
Score = 63.2 bits (152), Expect = 7e-09
Identities = 118/499 (23%), Positives = 167/499 (33%), Gaps = 104/499 (20%)
Query: 4534 SSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRG 4593
S L+ VR L QE L + P++ +F+ G+ VNG +L
Sbjct: 64 SGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYS 123
Query: 4594 AFGSGALPTGPDYYSQLLT------------KNNLSNPP------TPPSSLPPTPPPSVQ 4635
+ G P Y Q L ++S PP +PPS+ PP PP ++
Sbjct: 124 SVGD----LRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLE 179
Query: 4636 QKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMES 4695
P + P A L S D + P PP + +
Sbjct: 180 PP------PPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP--PAPP------LAFLA 225
Query: 4696 DEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDT 4755
P PA + +G FP G +W+ D AL+ RAS P P
Sbjct: 226 PPPPPVPAPAPPAPASPHTVGTRL--FPPGGVTKWKS-DVALNGRQAEATRASPPRSPAE 282
Query: 4756 KPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSY 4815
ALG P P T+ + S K+P
Sbjct: 283 PKGSALG---PNPEPHLTFPR-------------------------------SFKVP--- 305
Query: 4816 EVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDI 4875
P +P R + P + E P KE+G K+P P + P + ++ +
Sbjct: 306 ----PPTPVRTSSIPVQEAQEAPR-KEEGATKKAPSRLP--------LPPSFHIRPASQV 352
Query: 4876 LSLLKQESPAPEPPTQHSYTYNVS-NLDVRQLSA------PPPEEPSPPPSPLAPSPASP 4928
+P P+ P + T S L Q A PPP P PPP+P P PA P
Sbjct: 353 YP---DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP 409
Query: 4929 PTEPLVELP-TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKG-VR 4986
LP + A PP SS + +PKP PE S P W+ +
Sbjct: 410 LPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAP---VDWRDPSQ 466
Query: 4987 WKRLRLLLTIQKGSGRQED 5005
++LR L R+ED
Sbjct: 467 MEKLRNELAAYLCGSRRED 485
Score = 58.9 bits (141), Expect = 1e-07
Identities = 167/769 (21%), Positives = 247/769 (32%), Gaps = 98/769 (12%)
Query: 4267 PGPQTGPLQEL----GAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPP----------- 4311
PGP GP Q++ G P P P P PP L P + P PPP
Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTL 203
Query: 4312 SSPQEPKRPSQLPSPSSQLPTEAQLPP--THPGTPKPQGP----TLEPPPGRVSPAAAQL 4365
SSP P P +P P+ L A PP P P P P T PPG V+ + +
Sbjct: 204 SSPSIPTPPDFIP-PAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDV 262
Query: 4366 ADTLFSKGLGPWDPPDNLAETQKPEQSSLVPG---HLDQVNGQVVPEASQLSIKQEPREE 4422
A PP + AE P+ S+L P HL VP + + P +E
Sbjct: 263 ALNGRQAEATRASPPRSPAE---PKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQE 319
Query: 4423 PCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEG 4482
AQ R+ G AP P + H+ + G
Sbjct: 320 -----AQEAPRKEEGATKKAPSRL-------PLPPSFHIRPASQVYPDRAPEPDCPGELK 367
Query: 4483 LRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKE 4542
A + + + +++ P PL P + A+ L ++K
Sbjct: 368 ATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPP 427
Query: 4543 DGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPT 4602
G + +L P P N + AP P + +LR A
Sbjct: 428 AGFTKTPK-----SSSPALKPKPNPPSPENTASSAPVDWRDP-SQMEKLRNEL--AAYLC 479
Query: 4603 GPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSE 4662
G + L ++ P P S P + +K P+++ P
Sbjct: 480 GSRREDRFL--SHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDT---PPGVPEKSLGG 534
Query: 4663 RALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRF 4722
+L +T SL L + P + T VR +E S + SI G P+
Sbjct: 535 SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSI-GSLPPK- 592
Query: 4723 PHLGSGR----WEQEDRALSPVIPLIPRASIPVFPDT--KPYGALGLEVPGKL------- 4769
P L GR +D+ PV +P S + P T +P LG +P K
Sbjct: 593 PRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIP 652
Query: 4770 ----------------PVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPN 4813
P T + G + T A A + ++L++ K +
Sbjct: 653 PKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEK--D 710
Query: 4814 SYEVLFPESPA-RAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQ 4872
S PE PA + + P + EG + L P + A P T
Sbjct: 711 SGPAGQPEKPASQEVSTPSQARGEGSPSEATRL--------PTQGARSSAAFPPKTSPGG 762
Query: 4873 LDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEP 4932
++ L K + + P E PP P P ++ PT+
Sbjct: 763 GEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDE 822
Query: 4933 LVELP-TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLK 4980
L+ P T + E P L LA+ + K R+ G S P L+
Sbjct: 823 LLRHPVTGEVVERGSPMALLLAARQRA--QKGRSVGAALGRSSLPGSLR 869
Score = 57.0 bits (136), Expect = 5e-07
Identities = 212/933 (22%), Positives = 289/933 (30%), Gaps = 181/933 (19%)
Query: 4126 EASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGL 4185
EA S PH L+ PS+ T P P P+ P PP P P
Sbjct: 195 EALSPPHTLSSPSIP--------TPPDFIPPAP----PLAFLAPPPPPVPAPAP------ 236
Query: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245
P TVG GV + + L RQ + ++A P +
Sbjct: 237 PAPASPHTVGTRLFPPGGVT-------------KWKSDVALNGRQAEATRASPPRSPAEP 283
Query: 4246 PGTQTSPLQGLLGCQPQLGGFPGP-----QTGPLQELGAGPRPQ------GPPRLPAPPG 4294
G+ P P+ P P + P+QE PR + P RLP PP
Sbjct: 284 KGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP- 342
Query: 4295 ALSTGPVLGPVHP--TPPPSSPQEPKRPS----QLPSPSSQLPTEAQLPPTHPGTPKPQG 4348
+ P V+P P P P E K + +L SQ A PP P P P
Sbjct: 343 SFHIRPA-SQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPP-A 400
Query: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVP 4408
P L PP + PAA L + PP +T K +L P
Sbjct: 401 PPLPPPAPPLPPAAPPLPCAQKAA-----HPPAGFTKTPKSSSPALKPK----------- 444
Query: 4409 EASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLL--LAGPRSEAGHLLLQKL 4466
P E A A R+ P N L L G R E L +
Sbjct: 445 -------PNPPSPENTASSAPVDWRD----PSQMEKLRNELAAYLCGSRREDRFLSHRP- 492
Query: 4467 LRAKNVQLSTGRGSEGLRAEINGHIDSKLA-----GLEQKLQGTPSNKEDAAARKPLTPK 4521
V + G +G R + S A G+ +K G S E AA P
Sbjct: 493 --GPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPS 550
Query: 4522 PKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLP----LTEPAITANFS--- 4574
+ + D S +++R E R S A K+ K + LP L I N +
Sbjct: 551 VDYIPQ--DSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDD 608
Query: 4575 -LFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSL--PPTPP 4631
L P P + L GP + P PP + P TPP
Sbjct: 609 KLSKPVAKNLPPQSTTLLPTTSLQPKAMLGP-----AIPPKATPEPAIPPKATLWPATPP 663
Query: 4632 -----PSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHN 4686
P+ K +G T + P A++A K P
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQ 723
Query: 4687 QTEDVRMESDEDSDSPDSIVPASSPESIL---------GEEAPRF--PHLGSGRWEQEDR 4735
+ E S S + +P S G E P PH +E
Sbjct: 724 EVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE-- 781
Query: 4736 ALSPVIPLIPRASI------------PVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVS 4783
++ V+P + R P P P A + + PVT +GS ++
Sbjct: 782 -VAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
Query: 4784 VMLTVSAAAAKNLN-GVMVAVAELL-------------------SMKIPNSYEVLFPESP 4823
++L A K + G + + L S PNS+ V+ P+ P
Sbjct: 841 LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV-PKLP 899
Query: 4824 ARAGTE-PKKGEAEGPGGKEKG--LEGKSPDTGPDWLKQ-------FDAVLPGYTLKSQL 4873
A + P E G G EG +W K ++ V P +
Sbjct: 900 KEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGH- 958
Query: 4874 DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS------PAS 4927
L K S P P + N +V PPP E S P P AP+ +S
Sbjct: 959 ---PLPKSFSSPPSPSNKREEEEEEFNFEV----IPPPPEFSNDPEPPAPALQYLGRQSS 1011
Query: 4928 PPTEPLVELPTEPLAEPPVPSPLPLASSPESAR 4960
PP +L P A P P L + P AR
Sbjct: 1012 PPRNNYSDLRQLPNAGPGAPPALGFSRFPAGAR 1044
Score = 46.6 bits (109), Expect = 7e-04
Identities = 172/778 (22%), Positives = 253/778 (32%), Gaps = 149/778 (19%)
Query: 1955 SRERGGFFSPEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQ 2014
SR F S PG +P + G P P T LS + ++ LG
Sbjct: 481 SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETL------LSLPAKDTPPGVPEKSLGG 534
Query: 2015 LSTISPVLYANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRIN 2074
S ++ P++ DY S + ++ ++ A L A + A I
Sbjct: 535 SSLTETEAAPSLTLPSV--DYIPQDSPTPSVRQIRNELEAR-----LSSAAEKEAKPSIG 587
Query: 2075 KVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAG 2134
+ + + + + G K +P +PPQ L P + P +G P
Sbjct: 588 SLPPKPRLEGGRICENGADDDKLSKPVAK-NLPPQSTTL-LPTTSLQPKAMLGPAIPPKA 645
Query: 2135 LSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLE----PRFP 2190
A PP ++ P +P + L P P + S P PL+ P
Sbjct: 646 TPEPAI----PPKATL-WPATPPKA--TLGPATPLKATS------GPTTPLKATSGPAIA 692
Query: 2191 TAPPTYPPYPS---------PTGAPAQPPMLGASSRP---GAGQPGEFHTTPPGTPRHQP 2238
+ T P S P G P +P S+ G G P E P R
Sbjct: 693 STATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSA 752
Query: 2239 STPDP----------FLKPRC-------------PSL---------DNLAVPESPGV--- 2263
+ P KP C P+L + + V E PG+
Sbjct: 753 AFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAK 812
Query: 2264 --GGGKASEPLLSPPPFGE-----SRKALEVKKEELGASSPSYGPPNLGFVDSPSS-GTH 2315
+ ++ LL P GE S AL + + S G LG P S H
Sbjct: 813 PPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAA-LGRSSLPGSLRDH 871
Query: 2316 LGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSH--PDIFRPGS 2373
E + +F + TP + V P+ P +E L P+ P + R
Sbjct: 872 SHQAEASSDSIFHSQGTPNSFTVVPKLP------KEAEKDSPLTTEIPNKWGPRLGRDAE 925
Query: 2374 YTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAE 2433
T+ + T +P+P P + + P +LP P+S SS SP R E
Sbjct: 926 GTELSRRHNWT-KPEPQAPVAWERVAPSNLPQGH-----PLPKSFSSPPSPSNKREEEEE 979
Query: 2434 AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHK-PPRPQPPEVAF--KAGSLAHTSLG 2490
F + P P +S P P + PPR ++ AG A +LG
Sbjct: 980 EFNFEVIPP----PPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALG 1035
Query: 2491 AGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPP 2550
FPA AG L SG + ++ VGEP P
Sbjct: 1036 FSRFPAGARYAGAGGLERF--SGGGRSLIKKR-----------------LYVGEPHRGPG 1076
Query: 2551 VPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPL 2610
+P G + FGP P G P+ V + P G P G + G +
Sbjct: 1077 LPHGGTGRSLSSPNCFGPQP--GGPEMRR--VNSAGRAPPGGLHAPRLSLEGAARGAAEA 1132
Query: 2611 RPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAEL-PGTQDP 2667
+ + GS Y A+ RS T+ T GS + T + PGT+ P
Sbjct: 1133 KHKA-------PGSADYGFAPAAGRSPYTT---------TRYGSPINTFTVRPGTRHP 1174
Score = 46.2 bits (108), Expect = 9e-04
Identities = 101/438 (23%), Positives = 152/438 (34%), Gaps = 63/438 (14%)
Query: 3980 QSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039
QS TLL P Q + LGP +P K + P TL + T+ PA +AT
Sbjct: 621 QSTTLL-PTTSLQPKAMLGPAIPPKATPEPAIPPK--ATLWPATPPKATLGPATPLKATS 677
Query: 4040 GPST---HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQ-PSSLQLQPPL 4095
GP+T GP AI +T ++ T ++ P QP+ P+S ++ P
Sbjct: 678 GPTTPLKATSGP-AIASTATTLPTTTSQLMAEKDSG-------PAGQPEKPASQEVSTPS 729
Query: 4096 RLPGQ-QQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA----QPSVS---LGDQPGS 4147
+ G+ + + L T G S +S VP L Q S+S P
Sbjct: 730 QARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTL 789
Query: 4148 MTQNLLGPQQPMLER-----PMQNNTGPQP-------PKPGPVLQSGQGLPGVGIMPTVG 4195
GP +P+ + P + QP P G V++ G + +
Sbjct: 790 ARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRA 849
Query: 4196 QLRAQLQGVLAKNP---QLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSP 4252
Q + L ++ LR S Q + ++ + S V P + + SP
Sbjct: 850 QKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTV--VPKLPKEAEKDSP 907
Query: 4253 LQGLLGCQ--PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPP 4310
L + + P+LG + P PQ P V P+
Sbjct: 908 LTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWER-------------VAPSNL 954
Query: 4311 PSSPQEPKRPSQLPSPSSQLPTEAQ--------LPPTHPGTPKPQGPTLEPPPGRVSPAA 4362
P PK S PSPS++ E + PP P+P P L+ + SP
Sbjct: 955 PQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014
Query: 4363 AQLADTLFSKGLGPWDPP 4380
+D GP PP
Sbjct: 1015 NNYSDLRQLPNAGPGAPP 1032
Score = 45.1 bits (105), Expect = 0.002
Identities = 45/145 (31%), Positives = 57/145 (39%), Gaps = 12/145 (8%)
Query: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942
SP P PP+ L PPP +PPP P+ + + P T +PT P
Sbjct: 161 SPLPSPPS------TAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF 214
Query: 4943 EPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGV-RWKRLRLLLTIQKGSG 5001
PP P PL + P P P A P + RL GV +WK L Q +
Sbjct: 215 IPPAP-PLAFLAPPPPPVPAP-APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEAT 272
Query: 5002 RQEDEREVAEFMEQLGTALRPDKVP 5026
R R A E G+AL P+ P
Sbjct: 273 RASPPRSPA---EPKGSALGPNPEP 294
Score = 43.9 bits (102), Expect = 0.004
Identities = 99/457 (21%), Positives = 139/457 (30%), Gaps = 102/457 (22%)
Query: 4293 PGALSTGPVLGPVHPTPPPSSPQ---EPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349
PG ++ P P P P PQ EP S LPSP S P PP P P
Sbjct: 130 PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAP-----PPPPLLLEPPPPP 184
Query: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPE 4409
++ PPP V A + PP L+ P +P P
Sbjct: 185 SMAPPPPPVLEALS---------------PPHTLSSPSIPTPPDFIP-----------PA 218
Query: 4410 ASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRA 4469
+ P P G + PG + +
Sbjct: 219 PPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPG--------------------GVTKW 258
Query: 4470 KNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKED--AAARKPLTPKPKRVQK 4527
K+ GR +E RA + E K N E R P P V+
Sbjct: 259 KSDVALNGRQAEATRA------SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT 312
Query: 4528 ASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLT--------EPAITANFSLFAPF 4579
+S + +++ RKE+G L + P + EP AP
Sbjct: 313 SSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP- 371
Query: 4580 GSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMV 4639
P GQSQ + +G P PP PP + PP PPP+
Sbjct: 372 --ASPRLGQSQSQADERAGTPPPA---------------PPLPPPA-PPLPPPAPPLPPA 413
Query: 4640 NGVTPSEELGEHPKD--AASARDSERALRDTSEVKSLDLLAA---LPTPPHNQTEDVRME 4694
P + HP + + S AL+ S + A+ + +Q E +R E
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNE 473
Query: 4695 --------SDEDSDSPDSIVPASSPESILGEEAPRFP 4723
ED P +P+S G++ PR P
Sbjct: 474 LAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLP 510
Score = 40.4 bits (93), Expect = 0.049
Identities = 44/198 (22%), Positives = 68/198 (34%), Gaps = 40/198 (20%)
Query: 2771 RLSRPPPPATP--SSMDVNSRQLVGGSQAFYQRAPYP---GSLPLQQQQQQLWQQQQATA 2825
R S P PA P S++ N + ++F P P S+P+Q+ Q+ +++ AT
Sbjct: 273 RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332
Query: 2826 ATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQ 2885
R + F P ++ P + P P G + + + + +
Sbjct: 333 KAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS------QSQADER 386
Query: 2886 KGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNS 2945
G P P P PP P PP P+APP P +
Sbjct: 387 AGTPPPAPPLPPPAPPLPPP-----------------------APPLPPAAPPLPCAQKA 423
Query: 2946 LHP------TPHTKGPTL 2957
HP TP + P L
Sbjct: 424 AHPPAGFTKTPKSSSPAL 441
Score = 40.4 bits (93), Expect = 0.049
Identities = 136/636 (21%), Positives = 211/636 (33%), Gaps = 121/636 (19%)
Query: 4048 PLAIGTTPESM--ATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQV 4105
P TP+S A +P PS + V + Q L+ + L G +++
Sbjct: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR 486
Query: 4106 SLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQ 4165
L H G Q G + +P S+ D P + + LG
Sbjct: 487 FLSHRPGPTVAPQSKEGK--KGPRLPEKETLLSLPAKDTPPGVPEKSLGG---------- 534
Query: 4166 NNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAK------NPQLRHLSPQQQ 4219
++ P L S +P P+V Q+R +L+ L+ P + L P+ +
Sbjct: 535 SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPR 594
Query: 4220 QQLQALL---MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQE 4276
+ + + PP T+ LQ P GP
Sbjct: 595 LEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQ------------PKAMLGPAIP 642
Query: 4277 LGAGPRPQGPPRL---PAPPGALSTGPVL------GPVHPTPPPSSPQEPKRPSQLPSPS 4327
A P P PP+ PA P + GP GP P S P + LP+ +
Sbjct: 643 PKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTT 702
Query: 4328 SQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQ 4387
SQL E K GP +P PA+ +++ ++G G L TQ
Sbjct: 703 SQLMAE-----------KDSGPAGQPE----KPASQEVSTPSQARGEGSPSEATRL-PTQ 746
Query: 4388 KPEQSSLVPGHLDQVNGQV----VPEASQLSIKQE--------PREEPCALGAQSVKREA 4435
S+ P G+V P Q S+ +E R G +E
Sbjct: 747 GARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEP 806
Query: 4436 NGEPIGAPGTSNHL--LLAGP-------RSEAGHLLL---QKLLRAKNVQLSTGRGSEGL 4483
G P P ++ LL P R LLL Q+ + ++V + GR S L
Sbjct: 807 PGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSS--L 864
Query: 4484 RAEINGHIDSKLAGLEQ--KLQGTPSN-------KEDAAARKPLTPK------PKRVQKA 4528
+ H A + QGTP++ ++A PLT + P+ + A
Sbjct: 865 PGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDA 924
Query: 4529 SDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQ 4588
+S R K + +A + + S LP P + +FS P N +
Sbjct: 925 EGTELSRRHNWTKPE----PQAPVAWERVAPSNLPQGHP-LPKSFS-----SPPSPSNKR 974
Query: 4589 SQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPS 4624
+ F +P P++ SN P PP+
Sbjct: 975 EEEEEEFNFEVIPPPPEF----------SNDPEPPA 1000
Score = 38.9 bits (89), Expect = 0.14
Identities = 36/114 (31%), Positives = 45/114 (39%), Gaps = 28/114 (24%)
Query: 2867 PVPGPA-GPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLA 2925
P PGPA GP Q I PGG+P P P P P+ +P
Sbjct: 142 PPPGPAPGPPQDISEP--------PGGSPLPSP-PSTAPPPPPLLLEP------------ 180
Query: 2926 VSGLPPQKPSAPPAPELNNSLHPTPHT-KGPTLPTGLELVNRPPSSTELGRPNP 2978
PP APP P + +L P PHT P++PT + + P L P P
Sbjct: 181 ----PPPPSMAPPPPPVLEALSP-PHTLSSPSIPTPPDFIPPAPPLAFLAPPPP 229
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 130 bits (326), Expect = 5e-29
Identities = 143/523 (27%), Positives = 209/523 (39%), Gaps = 95/523 (18%)
Query: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL 494
+++M P P PPP++ P PPP+ + PPP P+ P A P +S
Sbjct: 743 HQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAA-----PAMKS-- 795
Query: 495 SPPP----EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF- 549
SPPP + L P S F P+ + P P P L L PPE S +PP
Sbjct: 796 SPPPFIATQVPVLEPQLPGSVFDPI--GHFTQPILHLPQPELPPHLPQPPEHS--TPPHL 851
Query: 550 -EESPLSPPP-----EELPTSPPPEASRLSPPPEESP-MSPPPEESPMSPPPEASRLFPP 602
+ + +SPP + P+ P A+ L P P P +SP ++P+ P PP
Sbjct: 852 NQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQ-------PP 904
Query: 603 FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL 662
+ P +E P +PP + ++ + PP +P+ P +V P P+
Sbjct: 905 MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP--TPLLPSVKVQSQPPPPL---- 958
Query: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEE 722
PPP + ++ P PPP P P+ PPP+ PP L P++
Sbjct: 959 -PPPPHPSVQQQLQQQPPPPPP------PQPQ-----PPPQQQHQPPPRPVHLQ--PMQF 1004
Query: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782
S + P PQ + PH P + P P+P +P Q + H SP+
Sbjct: 1005 STHIQQPPPPQ---GQQPPHPPPGQQPP--PPQPAKPQ---QVIQHHHSPR--------- 1047
Query: 783 PEEPHLSPQAEGPHL--SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS--- 837
H S HL +P P +H SPQ + P + QP++ L S
Sbjct: 1048 ---HHKSDPYSTGHLREAPSPLMIH-SPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQ 1103
Query: 838 EEPCLSPRPEESHLSPELEKPPLSP--RPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895
+P + + E+ H SP + P SP RPE PP+ P AP L P P + P+
Sbjct: 1104 PQPLVVVKEEKIH-SPIIRSEPFSPSLRPE-PPKHPESIKAPVHL-----PQRPEMKPV- 1155
Query: 896 GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM-PPDPLPP 937
+ G P + P + P P G P Q P P+ P
Sbjct: 1156 ------DVGRPVIRPPEQNAP--PPGAPDKDKQKQEPKTPVAP 1190
Score = 125 bits (313), Expect = 2e-27
Identities = 135/500 (27%), Positives = 196/500 (39%), Gaps = 104/500 (20%)
Query: 429 QLEAPLNEEMPLLPPPEESPLSPPPEES--PTSPPP---------EASRLSPPP------ 471
Q AP+ ++ P PPP++ P PPP++ P PPP A + SPPP
Sbjct: 748 QAPAPVPQQPP--PPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQV 805
Query: 472 ----EELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPP---- 523
+LP S H ++P+ P P P PP S+P + + +SPP
Sbjct: 806 PVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLP-QPPEHSTPPHLNQHAVVSPPALHN 864
Query: 524 --EESPPSPALETPLSPPPEASP--LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579
+ P P+ PP A P +SP ++PL P P P + PP+ +E
Sbjct: 865 ALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQP---PMAQPPQVLL----EDEE 917
Query: 580 PMSPPPEESPMS-PPPEASRLFPPFEESP-----LSPPPEESPLSPPPEAS-----RLSP 628
P +PP M + ++ PP P PPP PL PPP S + P
Sbjct: 918 PPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPP---PLPPPPHPSVQQQLQQQP 974
Query: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
PP P PP + PPP L P+ + + PP PP + P PPP +
Sbjct: 975 PPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPP------PPQGQQPPHPPP--GQ 1026
Query: 689 LSPPPEDSPTSPPPEDSPASPP---PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP 745
PPP+ P P P D + L E+P + PQ+ H SP
Sbjct: 1027 QPPPPQ--PAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSP 1084
Query: 746 RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE----PHLSPQAEGPHLSPQP 801
P + +P++ L + + PQP L V EE P + + P L P+P
Sbjct: 1085 ----PQQNVQPKKQELRAASV---VQPQP----LVVVKEEKIHSPIIRSEPFSPSLRPEP 1133
Query: 802 EELHLSPQTEEPHLSPV--PEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPP 859
P+ E +PV P+ P + P P + P PE++ PP
Sbjct: 1134 ------PKHPESIKAPVHLPQRPEMKP--------VDVGRPVIRP-PEQN------APPP 1172
Query: 860 LSPRPEKPPEEPGQCPAPEE 879
+P +K +EP AP++
Sbjct: 1173 GAPDKDKQKQEPKTPVAPKK 1192
Score = 100 bits (248), Expect = 5e-20
Identities = 121/466 (25%), Positives = 160/466 (34%), Gaps = 48/466 (10%)
Query: 347 HRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDT---------PTDEPDALYVACQGQPK 397
H H Q Q V +Q P + PP P P P A + P
Sbjct: 739 HHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPP 798
Query: 398 GGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESP 457
T + EP Q G +P L P E P LP P E P +
Sbjct: 799 PFIATQVPVLEP---QLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHA 855
Query: 458 TSPPPEASRLSPPPEELPASPLPEALHL-SRPLEESPLSPPPEESPLSP-PPESSPFSPL 515
PP P + P+ P A L +P +SP ++PL P PP + P L
Sbjct: 856 VVSPPALHNALP---QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVL 912
Query: 516 --EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEAS--- 570
+E P +PP S L +PL P + PPP LP P P
Sbjct: 913 LEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP--LPPPPHPSVQQQL 970
Query: 571 RLSPPPEESPMSPPPEESPMSPPPEASRLFP-PFEESPLSPPPEESPLSPPPEASRLSPP 629
+ PPP P PP + PPP L P F PPP + P P + PP
Sbjct: 971 QQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP 1030
Query: 630 PEDSPMSPPP----EESP---MSPPPEVSRL----SPLPVVSRLSPPPEESPLSPPPEES 678
P+ P P SP S P L SPL + S + PP+++
Sbjct: 1031 PQ--PAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQN 1088
Query: 679 PTSPPPE---ASRLSPPP-----EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730
E AS + P P E+ SP P SP P + LP+
Sbjct: 1089 VQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQ 1148
Query: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776
P++ P G + PE+ +P P P Q +EP P++
Sbjct: 1149 RPEMKPVDVGRPVIRPPEQN--APPPGAPDKDKQKQEPKTPVAPKK 1192
Score = 87.8 bits (216), Expect = 3e-16
Identities = 138/624 (22%), Positives = 209/624 (33%), Gaps = 110/624 (17%)
Query: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGAS------SRP 2218
PQ P P Q P P +P P PP+ P +P + PP + P
Sbjct: 754 PQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLP 813
Query: 2219 GA--GQPGEF-----HTTPPGTPRHQPSTPDPFLKPRC--------PSLDNLAVPESPGV 2263
G+ G F H P P H P P+ P P+L N A+P+ P
Sbjct: 814 GSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHN-ALPQQPSR 872
Query: 2264 GGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKT 2323
+A+ L P P + + + L P PP + D L ++++
Sbjct: 873 PSNRAA--ALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQ- 929
Query: 2324 PDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL 2383
+ P P + ++ Q PPP PP HP + QPP
Sbjct: 930 ---LYLQQLQKVQPPTPLLPSVKVQSQPPPPL-----PPPPHPSV-----QQQLQQQPPP 976
Query: 2384 TPRPQP-PPPESCCALPPRSLPSDPFS-----RVPASPQSQS-----SSQSPLTPRPLSA 2432
P PQP PPP+ PPR + P + P PQ Q Q P P+P
Sbjct: 977 PPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKP 1036
Query: 2433 EAFCPSPVTPRFQSPDPYS-----RPPS-----RPQSRDPFAPLHKPP---RPQPPEVAF 2479
+ +PR DPYS PS PQ + H+ P QP +
Sbjct: 1037 QQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQEL 1096
Query: 2480 KAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP------------PNFVRSPGTGAF 2527
+A S+ P L ++H+ + +P P +++P
Sbjct: 1097 RAASVVQ--------PQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAP----- 1143
Query: 2528 VGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNF 2587
V P P VG P ++P P+ PPP G + Q VA
Sbjct: 1144 VHLPQRPEMK-PVDVGRPVIRP--PEQNAPPP-------GAPDKDKQKQEPKTPVA---- 1189
Query: 2588 HPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRED 2647
P + GS P P S + S A ++ ++ + +
Sbjct: 1190 -PKKDLKIKNMGSWASLVQKHPTTPSST--AKSSSDSFEQFRRAAREKEEREKALKAQAE 1246
Query: 2648 PGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETA 2707
L + +D ++ E+ R+RQ +QQ QR +Q+++
Sbjct: 1247 HAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQE------QQQQQRQEQQQQQQQQ 1300
Query: 2708 AAAAGAVGPPGSWGAEPSSPAFEQ 2731
AAA A P + ++P S +Q
Sbjct: 1301 AAAVAAAATPQAQSSQPQSMLDQQ 1324
Score = 86.7 bits (213), Expect = 6e-16
Identities = 212/1003 (21%), Positives = 330/1003 (32%), Gaps = 206/1003 (20%)
Query: 366 TPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG---KA 422
TPV + PP+P TP P QP+ + QP + P A P K
Sbjct: 236 TPVMT-VVPPQPLQTPPPVPP--------QPQPPPAPAPQPVQSHPPIIAATPQPVKTKK 286
Query: 423 GVQLEPQLEAPLN----EEMPLLPPPEES-----------PLSPPPEESPTS---PPPEA 464
GV+ + P E P LPP ++ P+ PP ++ P S P PE
Sbjct: 287 GVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEK 346
Query: 465 SRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLS----------PPPESSPFSP 514
S + + L E P P + L P S+ S
Sbjct: 347 SSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSK 406
Query: 515 LEESPLSPPEESPPSPALETP----LSPPPE-----ASPLSPPFEESPLSPPPEELPTSP 565
LE +E L +PP A L FE P E P P
Sbjct: 407 LEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE--PEEP 464
Query: 566 PPEASRLSPPPEESPMSPPPEE---SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
S + PP ++PP S S ++S E + +E + +
Sbjct: 465 VVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQ 524
Query: 623 ASRLSPPPEDSPMSPPPE--ESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680
+ LS P ++ P + E + PPP+++ + + +
Sbjct: 525 LAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVS 584
Query: 681 SPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG 740
P + PPP T E+ P + L L+ + LP E
Sbjct: 585 KKEPAPMKSKPPP----TYESEEEDKCKPMSYEEKRQLSLD---INKLPGEKL----GRV 633
Query: 741 PHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQ 800
H+ E + P+E + + +P + E + ++ PQAE +
Sbjct: 634 VHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKR--KPQAEKVDVIAG 691
Query: 801 PEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE---PCLSPRPEESHLSPELEK 857
++ +E S E + E+ ++P+S++ P + H ++++
Sbjct: 692 SSKMKGFSSSESESSS---ESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQ 748
Query: 858 PP--LSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSP----L 911
P + +P PP++P P P++ PPP P P PA+ P ++ L
Sbjct: 749 APAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVL 808
Query: 912 PEELPLS---PSG----------EPSLSPQL-MPPDPLPPPLSPIITAAAPPAL-SPLGE 956
+LP S P G +P L P L PP+ PP +PPAL + L +
Sbjct: 809 EPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQ 868
Query: 957 LEYPFGAKGDSDPESPLAAP-----ILETPISP------PPEANCTDPEP-VPPM----- 999
+ + P P P + +TP+ P PP+ D EP PP+
Sbjct: 869 QPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQM 928
Query: 1000 ---------ILPPSPGSPVGPASPILMEPLPPQCSPLLQHSL--VPQNSPPSQCSPPALP 1048
+ PP+P P PLPP P +Q L P PP Q PP
Sbjct: 929 QLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQ 988
Query: 1049 LSVPSP----LSPIGKVVGVSD------EAELHEMETEKVSEPECPALEPSATSPLPSPM 1098
P P L P+ + + H ++ P+ PA SP
Sbjct: 989 QHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQ-PAKPQQVIQHHHSPR 1047
Query: 1099 GDLSCP--------APSP----APALDDFSGLGEDTAPLDGID----------------- 1129
S P APSP +P + F L + P +
Sbjct: 1048 HHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPL 1107
Query: 1130 ------------------APGSQPEPGQTPGSLAS--------ELK----GSPVLLDPEE 1159
+P +PEP + P S+ + E+K G PV+ PE+
Sbjct: 1108 VVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQ 1167
Query: 1160 LAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKS 1202
AP G ++++EP+ PVAP IK+
Sbjct: 1168 NAP------------PPGAPDKDKQKQEPKTPVAPKKDLKIKN 1198
Score = 84.0 bits (206), Expect = 4e-15
Identities = 188/889 (21%), Positives = 293/889 (32%), Gaps = 192/889 (21%)
Query: 449 LSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPE 508
+S P + S PP+ P P + A+P P + ++P+ PL PP
Sbjct: 193 VSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPP- 251
Query: 509 SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE-----------ESPLSPP 557
P+ P + PP+PA + S PP + P + +P +
Sbjct: 252 ----------PVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTID 301
Query: 558 PEELPTSPPPE--ASRLSPPPEES-PMSPPPEESPMS---PPPEASR------------L 599
P P S PPE ++L E S P+ PP ++ P S P PE S L
Sbjct: 302 PIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGIL 361
Query: 600 FPPFEES------PLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653
F + P P + L + P + S + E E
Sbjct: 362 KEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGAD 421
Query: 654 SPLPVVS--RLSPPPEE----------------SPLSPPPEE------SPTSPPPEASRL 689
L + + +PP E + + PEE SP PPP +
Sbjct: 422 VRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPP-TKVV 480
Query: 690 SPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE 749
+PP +S DS +S + + L E QL S+ P+ +E
Sbjct: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
Query: 750 PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSP- 808
+ +E H + E + + +EP P++ + + +P + P
Sbjct: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEP----PPKKTKKNNSSNSNVSKKEPAPMKSKPP 596
Query: 809 ----QTEEPHLSPVPEEP------CLSPQPEES-----HLSPQSEEPCL-SPRPEESHLS 852
EE P+ E ++ P E H+ QS EP L + P+E +
Sbjct: 597 PTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHII-QSREPSLKNSNPDEIEID 655
Query: 853 PELEKPPL----------------SPRPEK-----------------------PPEEPGQ 873
E KP P+ EK +
Sbjct: 656 FETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSE 715
Query: 874 CPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP---QLM 930
E P G P + + +P+P++ P P P P Q
Sbjct: 716 DSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQ 775
Query: 931 PPDPLPPP-----LSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPIS-- 983
PP P PPP +P + ++ PP ++ + P DP PIL P
Sbjct: 776 PPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPEL 835
Query: 984 ----PPPEANCTDPE------PVPPMI---LPPSPGSPVGPASPILMEPL-PPQCSP-LL 1028
P P + T P PP + LP P P A+ + +P PP SP L
Sbjct: 836 PPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALT 895
Query: 1029 QHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEP 1088
Q L+PQ P PP + L P +P + + + L +++ + P P+++
Sbjct: 896 QTPLLPQ---PPMAQPPQVLLEDEEPPAP--PLTSMQMQLYLQQLQKVQPPTPLLPSVKV 950
Query: 1089 SATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASEL 1148
+ P P P P P P++ L + P P QP+P P +
Sbjct: 951 QSQPPPPLP--------PPPHPSVQ--QQLQQQPPP-----PPPPQPQP---PPQQQHQP 992
Query: 1149 KGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPP 1197
PV L P + + T ++ Q P + Q+ P P PP
Sbjct: 993 PPRPVHLQPMQFS--THIQ----------QPPPPQGQQPPHPPPGQQPP 1029
Score = 74.3 bits (181), Expect = 3e-12
Identities = 99/457 (21%), Positives = 180/457 (39%), Gaps = 72/457 (15%)
Query: 3557 PEADAEKLKLVTEQQSKIQKQ---LDQVRKQQKEHTNLMAEYRNKQQQQQQQQ------- 3606
P + +++L +Q K+Q L V+ Q + L QQQ QQQ
Sbjct: 921 PPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPP 980
Query: 3607 ------QQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPG 3660
QQQ Q + L P Q + + P P G QPP PPG Q
Sbjct: 981 QPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPP----PPQGQQPPHPPPGQQPP------- 1029
Query: 3661 GMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQ 3720
P QP P QQ Q H + P + G+L P ++ Q
Sbjct: 1030 ----PPQPAKP-------QQVIQHHHSPRHHKSDP---YSTGHLRE---APSPLMIHSPQ 1072
Query: 3721 LQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPS 3780
+ Q L + QQ Q ++Q L +Q Q + K + + P
Sbjct: 1073 MS---QFQSLTHQSPPQQNVQPKKQELRAASVVQPQP----------LVVVKEEKIHSPI 1119
Query: 3781 SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQL 3840
L P+PP+ P+ + P + + P +G R V+ + P
Sbjct: 1120 IRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVG-----RPVIRPPEQNAPPPGA 1174
Query: 3841 AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQL 3900
+ + + A ++ + ++ GS A L +Q+ + S K S+ ++
Sbjct: 1175 PDKDKQKQEPKTPVAPKKDLKIKNM--GSWASL--VQKHPTTPSSTAKSSSDSFEQFRRA 1230
Query: 3901 QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ 3960
++++ ++++ L+ Q + +++++L+Q++++ ++ + L+Q ++ ++ +++Q+
Sbjct: 1231 AREKE-EREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAH-----EEARRRQE 1284
Query: 3961 QQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVAL 3997
QQQQQ Q+QQQQQQ + Q Q Q L
Sbjct: 1285 QQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSML 1321
Score = 66.2 bits (160), Expect = 8e-10
Identities = 79/354 (22%), Positives = 119/354 (33%), Gaps = 61/354 (17%)
Query: 395 QPKGGHVTSMQPK----------EPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPP 444
+P +TSMQ + P PL K + L P + +++ PPP
Sbjct: 917 EPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPP 976
Query: 445 EESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLS 504
P PP + PPP L P+ + H+ +P PP + P
Sbjct: 977 PPPPQPQPPPQQQHQPPPRPVHL---------QPMQFSTHIQQP------PPPQGQQPPH 1021
Query: 505 PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTS 564
PPP P PP+ + P ++ SP S P+ L P L
Sbjct: 1022 PPPGQQP---------PPPQPAKPQQVIQHHHSPRHHK---SDPYSTGHLREAPSPLMIH 1069
Query: 565 PPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEAS 624
P MS + SPP + + P +E + + PL E
Sbjct: 1070 SP-------------QMSQFQSLTHQSPPQQ--NVQPKKQELRAASVVQPQPLVVVKEEK 1114
Query: 625 RLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPP 684
SP P SP P P + LP + P P+ PPE++ +PPP
Sbjct: 1115 IHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQN--APPP 1172
Query: 685 EASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
A P +D P +P +P + + ++ S + P P +S
Sbjct: 1173 GA-----PDKDKQKQEP--KTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKS 1219
Score = 62.8 bits (151), Expect = 9e-09
Identities = 93/389 (23%), Positives = 131/389 (33%), Gaps = 53/389 (13%)
Query: 2110 PGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGEL---------- 2159
P SPPP A + + P P + F +P +P P+ P L
Sbjct: 791 PAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPIL-HLPQPELPPHLPQPPEHSTPP 849
Query: 2160 -----FLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGA 2214
+ PP + +P Q A L P+ P PP P + T QPPM
Sbjct: 850 HLNQHAVVSPPALHNALPQQPSRPSNRAAALPPK-PARPPAVSPALTQTPLLPQPPM--- 905
Query: 2215 SSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLS 2274
+ P E PP T K + P+ P P V P L
Sbjct: 906 AQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPT------PLLPSVKVQSQPPPPLP 959
Query: 2275 PPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPR 2334
PPP ++ L+ ++ P PP P HL ++ T
Sbjct: 960 PPPHPSVQQQLQ--QQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFST----------- 1006
Query: 2335 ASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSY------TDPYAQPPLTPRPQ 2388
++ P G +P PPP Q P P+ P + +DPY+ L P
Sbjct: 1007 --HIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPS 1064
Query: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQS-SSQSPLTPRPLSA--EAFCPSPVTPRFQ 2445
P S +SL + P+ Q + S + P+PL E SP+
Sbjct: 1065 PLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEP 1124
Query: 2446 -SPDPYSRPPSRPQSRDPFAPLHKPPRPQ 2473
SP PP P+S AP+H P RP+
Sbjct: 1125 FSPSLRPEPPKHPESIK--APVHLPQRPE 1151
Score = 58.9 bits (141), Expect = 1e-07
Identities = 105/476 (22%), Positives = 142/476 (29%), Gaps = 82/476 (17%)
Query: 2349 PQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPF 2408
PQ+PPP P PP PP + PPPP PP S+P
Sbjct: 754 PQQPPPPPQQPPPPP-----------------PPQQQQQPPPPP------PPPSMPQQAA 790
Query: 2409 SRVPASPQSQSSSQSPLTPRPLSAEAFCP-------------SPVTPRFQSPDPYSRPPS 2455
+ +SP ++Q P+ L F P + P P +S PP
Sbjct: 791 PAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPH 850
Query: 2456 RPQSRDPFAP-LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQ 2514
Q P LH QP + +A +L PA PA L + P Q
Sbjct: 851 LNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARP---PAVSPALTQTPLLPQPPMAQ 907
Query: 2515 PPNFV---RSPGTGAFVGTPSPMRFTFPQAVGEPS---------LKPPVPQPGLPPPH-G 2561
PP + P + Q V P+ +PP P P PPPH
Sbjct: 908 PPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLP--PPPHPS 965
Query: 2562 INSHF------GPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSV 2615
+ P P P + H G P PP
Sbjct: 966 VQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPG 1025
Query: 2616 LPPPAPDGSLP--YLSHGASQRSGITSPVEK---REDPGTGMGSSLATAELPGTQDPGMS 2670
PP P + P + H S R + P RE P M + Q
Sbjct: 1026 QQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLM--------IHSPQMSQFQ 1077
Query: 2671 GLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFE 2730
L+ +Q + + +EL +Q L KE + P S P P
Sbjct: 1078 SLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHP 1137
Query: 2731 QLSRG-----QTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATP 2781
+ + Q P D V PP + + P PG+ D + P P P
Sbjct: 1138 ESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPP---PGAPDKDKQKQEPKTPVAP 1190
Score = 56.2 bits (134), Expect = 9e-07
Identities = 95/389 (24%), Positives = 121/389 (31%), Gaps = 71/389 (18%)
Query: 4079 QPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPS 4138
QP P P P Q PP P QQ + S A+ VP L Q
Sbjct: 763 QPPPPPPPQQQQQPPPPPPPPSMPQQAA---------PAMKSSPPPFIATQVPVLEPQLP 813
Query: 4139 VSLGDQPGSMTQNLLGPQQPMLE----RPMQNNTGPQ--------PPKPGPVLQSGQGLP 4186
S+ D G TQ +L QP L +P +++T P PP L P
Sbjct: 814 GSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRP 873
Query: 4187 G--VGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQ 4244
+P + L + P L P Q Q LL + PP
Sbjct: 874 SNRAAALPPKPARPPAVSPALTQTPLLPQ--PPMAQPPQVLLEDEE-------PPAPPLT 924
Query: 4245 EPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGP 4304
Q LQ L QP P P ++ P P PP P+ L P
Sbjct: 925 SMQMQLY-LQQLQKVQP-----PTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQP---- 974
Query: 4305 VHPTPPPSSPQEPKRPSQLPSP------SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRV 4358
P PPP PQ P + P P Q T Q PP G P PPPG+
Sbjct: 975 --PPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPP-----HPPPGQQ 1027
Query: 4359 SPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVP---GHLDQVNGQVVPEASQLSI 4415
P P P + P P GHL + ++ + Q+S
Sbjct: 1028 PPPPQ------------PAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQ 1075
Query: 4416 KQE-PREEPCALGAQSVKREANGEPIGAP 4443
Q + P Q K+E + P
Sbjct: 1076 FQSLTHQSPPQQNVQPKKQELRAASVVQP 1104
Score = 55.8 bits (133), Expect = 1e-06
Identities = 108/438 (24%), Positives = 145/438 (33%), Gaps = 88/438 (20%)
Query: 4080 PQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSE---ASSVPHLLAQ 4136
P PQ P Q PP P QQQQ SS A+ VP L Q
Sbjct: 752 PVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQ 811
Query: 4137 PSVSLGDQPGSMTQNLLGPQQ----PMLERPMQNNTGPQ----------------PPKPG 4176
S+ D G TQ +L Q P L +P +++T P P +P
Sbjct: 812 LPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPS 871
Query: 4177 PVLQSGQGLP-----GVGIMPTVGQLRAQLQGVLAKNPQ-LRHLSPQQQQQLQALLMQRQ 4230
LP + P + Q Q +A+ PQ L L ++ MQ
Sbjct: 872 RPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLY 931
Query: 4231 LQQSQAVR-QTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRL 4289
LQQ Q V+ TP Q+ P P L P P Q+L P P PP+
Sbjct: 932 LQQLQKVQPPTPLLPSVKVQSQP-------PPPLP--PPPHPSVQQQLQQQPPPPPPPQ- 981
Query: 4290 PAPPGALSTGPVLGPVH----------PTPPPSSPQEPKRP---SQLPSPSSQLPTEA-- 4334
P PP P PVH PPP Q+P P Q P P P +
Sbjct: 982 PQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQ 1041
Query: 4335 --QLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE-- 4390
P H P G E P SP + L PP + +K E
Sbjct: 1042 HHHSPRHHKSDPYSTGHLREAP----SPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELR 1097
Query: 4391 ------QSSLVPGHLDQVNGQVV----------------PEA--SQLSIKQEPREEPCAL 4426
LV ++++ ++ PE+ + + + Q P +P +
Sbjct: 1098 AASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDV 1157
Query: 4427 GAQSVK-REANGEPIGAP 4443
G ++ E N P GAP
Sbjct: 1158 GRPVIRPPEQNAPPPGAP 1175
Score = 53.1 bits (126), Expect = 7e-06
Identities = 115/514 (22%), Positives = 171/514 (33%), Gaps = 84/514 (16%)
Query: 3543 CAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQ 3602
C +++ +A + A + K+K + +S+ + + E MA K+
Sbjct: 674 CLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETE--MAPKSKKKGHP 731
Query: 3603 QQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGM 3662
++Q++ H + +P+ P+ P Q P Q Q PP
Sbjct: 732 GREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAP 791
Query: 3663 ALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQ 3722
A+ P PF+ T + + Q GS+ P G F + L
Sbjct: 792 AMKSSPP-PFIATQVPVLEPQL----PGSVFDPIGHF-----------------TQPILH 829
Query: 3723 LQQQRM--QLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPS 3780
L Q + L Q + Q ++ A+ Q P +N+A P+ PP+
Sbjct: 830 LPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPA 889
Query: 3781 SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQL 3840
L L PQPP M P QV +L+ + P P P
Sbjct: 890 VSPALTQTPLLPQPP-----MAQPPQV-LLEDEEP----PAPP----------------- 922
Query: 3841 AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQL 3900
L + Q Q QQ Q+ L L + P L P S+QQ
Sbjct: 923 -----------LTSMQMQLYLQQLQKVQPPTPL--LPSVKVQSQPPPPLPPPPHPSVQQQ 969
Query: 3901 QQQQ----QLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQ 3956
QQQ Q Q QQQ Q + LQ Q QQ Q QQ QQ
Sbjct: 970 LQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPP 1029
Query: 3957 QQQQQQQQQFQQQQQQQQ--------MGLLNQSRTLL---SPQQQQQQQVA--LGPGMPA 4003
Q + QQ Q + G L ++ + L SPQ Q Q + P
Sbjct: 1030 PPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNV 1089
Query: 4004 KP-LQHFSSPGALGPTLLLTGKEQNTVDPAVSSE 4036
+P Q + + P L+ KE+ P + SE
Sbjct: 1090 QPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSE 1123
Score = 50.4 bits (119), Expect = 5e-05
Identities = 84/390 (21%), Positives = 140/390 (35%), Gaps = 38/390 (9%)
Query: 3252 LLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQ 3311
LL K + Q L P+ QQQ QQQ P P Q P + P
Sbjct: 944 LLPSVKVQSQPPPPLPPPPHPSVQQQLQQQP----PPPPPPQPQPPPQQQHQPPPRPVHL 999
Query: 3312 QLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQ 3371
Q +QP PQ P PP QQ P A ++ H P+
Sbjct: 1000 QPMQFSTHIQQPPPPQGQQPPHPPPG--QQPPPPQPAKPQQ---VIQHHHS------PRH 1048
Query: 3372 SSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLD----KFAAEDIIDP---- 3423
S + P + + Q++ Q L + P ++ + A ++ P
Sbjct: 1049 HKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLV 1108
Query: 3424 IAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSL---LAQRLSGGPSSDLQNHVAAGSGQ 3480
+ K + + I+ S+ P + + + L QR P D+ V
Sbjct: 1109 VVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPV-DVGRPVIRPP-- 1165
Query: 3481 ERSAGDPSQP----RPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHR 3536
E++A P P + P + + W Q+ +
Sbjct: 1166 EQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFE 1225
Query: 3537 KSRKALCAKQRTAK--KAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAE 3594
+ R+A K+ K KA E E + E+L+ +++ + ++ D + + ++ H
Sbjct: 1226 QFRRAAREKEEREKALKAQAEHAEKEKERLR---QERMRSREDEDALEQARRAHEEARRR 1282
Query: 3595 YRNKQQQQQQQQQQQQQQHSAVLALSPSQS 3624
+QQQ+Q+QQQQQQQQ +AV A + Q+
Sbjct: 1283 QEQQQQQRQEQQQQQQQQAAAVAAAATPQA 1312
Score = 47.0 bits (110), Expect = 5e-04
Identities = 108/422 (25%), Positives = 145/422 (34%), Gaps = 84/422 (19%)
Query: 3755 QQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGM---LGPA------ 3805
QQ QQ P Q P PQ PP Q QQ P PP P M PA
Sbjct: 744 QQMQQAPAPVPQQP-PPPPQQPPPPPPPQ----QQQQPPPPPPPPSMPQQAAPAMKSSPP 798
Query: 3806 -----QVAVLQQQHPGAL-GPQGPHRQVLMTQSRVLSSPQLAQQGQG-----LMGHRLVT 3854
QV VL+ Q PG++ P G Q ++ + P L Q + L H +V+
Sbjct: 799 PFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVS 858
Query: 3855 AQQQQQ---QQQHQQQGSMAGLSH-----------------LQQSLMSHSGQPKLS---- 3890
QQ + A L L Q M+ Q L
Sbjct: 859 PPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEP 918
Query: 3891 -AQPMGSLQQ---LQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQ 3946
A P+ S+Q LQQ Q++Q L + Q Q L QQQLQQQ
Sbjct: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPP--PHPSVQQQLQQQPPP 976
Query: 3947 QLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALG----PGMP 4002
Q Q QQQ Q + Q Q + Q PQ QQ G P P
Sbjct: 977 PPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPP---PPQGQQPPHPPPGQQPPPPQP 1033
Query: 4003 AKP---LQHFSSPGALGPTLLLTGKEQNTVDPAV--SSEATEGPS-THQGGP-------- 4048
AKP +QH SP TG + P + S + ++ S THQ P
Sbjct: 1034 AKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKK 1093
Query: 4049 ------LAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQ 4102
+ P + E P + + ++P+P P S ++ P+ LP + +
Sbjct: 1094 QELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPES--IKAPVHLPQRPE 1151
Query: 4103 QQ 4104
+
Sbjct: 1152 MK 1153
Score = 45.1 bits (105), Expect = 0.002
Identities = 76/301 (25%), Positives = 113/301 (37%), Gaps = 29/301 (9%)
Query: 2145 PPAGSVPGPDSPGELFLKLP-PQVPAQVPSQDP-FGLAPAYPLEPRFPTAP-PTYPPYPS 2201
PP P P+ P P P V + Q P + P PL+ P P P PP P+
Sbjct: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
Query: 2202 PTGAPAQPPMLGASSRPGAGQPG---EFHTTPPGT--PRHQPSTPDPFLKPRCPSLDNLA 2256
P + PP++ A+ +P + G + TT P T P H+P + P +P+ L
Sbjct: 265 PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPP--EPKTTKLGQRR 322
Query: 2257 VPESPGVGGGK-ASEPLLSPPPFGESRKALEVK------KEELGASSPSYGPPNLGFVDS 2309
P K + P P S+ + ++K KE +Y P VD
Sbjct: 323 ESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDV 382
Query: 2310 PSSGTHLGGLELKTP---DVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHP 2366
+ G H +K P K+ L R + + Q G +R + +PP H
Sbjct: 383 EALGLHDYCDIIKHPMDMSTIKSKLEAREYR-DAQEFGADVRLMF---SNCYKYNPPDHE 438
Query: 2367 DIFRPGSYTD----PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQ 2422
+ D +A+ P P +P S A+PP + P S +S S S S
Sbjct: 439 VVAMARKLQDVFEMRFAKMPDEPE-EPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSD 497
Query: 2423 S 2423
S
Sbjct: 498 S 498
Score = 44.7 bits (104), Expect = 0.003
Identities = 55/195 (28%), Positives = 78/195 (40%), Gaps = 29/195 (14%)
Query: 4275 QELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEA 4334
Q++ P P P+ P PP P P PPP Q+ + P P PS +P +A
Sbjct: 744 QQMQQAPAPV--PQQPPPP----------PQQPPPPPPPQQQQQPPPPPPPPS--MPQQA 789
Query: 4335 QLPPTHPGTPKP----QGPTLEPP-PGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389
P +P P Q P LEP PG V + L + P +L Q P
Sbjct: 790 --APAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILH--LPQPELPPHL--PQPP 843
Query: 4390 EQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHL 4449
E S+ P HL+Q + V P A ++ Q+P P A + A + T L
Sbjct: 844 EHST--PPHLNQ-HAVVSPPALHNALPQQP-SRPSNRAAALPPKPARPPAVSPALTQTPL 899
Query: 4450 LLAGPRSEAGHLLLQ 4464
L P ++ +LL+
Sbjct: 900 LPQPPMAQPPQVLLE 914
Score = 44.3 bits (103), Expect = 0.003
Identities = 126/563 (22%), Positives = 184/563 (32%), Gaps = 100/563 (17%)
Query: 3857 QQQQQQQHQQQGSMAGLSHLQ--QSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQ 3914
+++++ Q ++ +AG S ++ S S S S+ S ++ + + + +Q
Sbjct: 676 RKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQ 735
Query: 3915 QQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ--QQQQQFQQQQQQ 3972
++ QQ Q QQ QQ QQQQQ QQ +
Sbjct: 736 KKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKS 795
Query: 3973 QQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSP------GALGPTLLLTGKE- 4025
+ +L PQ PG P+ HF+ P L P L +
Sbjct: 796 SPPPFIATQVPVLEPQL---------PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHS 846
Query: 4026 ------QNTV--DPAVSSEATEGPSTHQGGPLAIGTTPE-------SMATEPGEVKPSLS 4070
Q+ V PA+ + + PS A+ P ++ P +P ++
Sbjct: 847 TPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMA 906
Query: 4071 GDSQLLLVQPQPQPQP-SSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASS 4129
Q+LL +P P +S+Q+Q L+ + Q LL + S S
Sbjct: 907 QPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSV 966
Query: 4130 VPHLLAQPSVSLGDQPGSMTQNLLGP------------------------QQPMLERPMQ 4165
L QP QP Q P QQP P Q
Sbjct: 967 QQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQ 1026
Query: 4166 NNTGPQPPKPGPVLQSGQGLPGVGIMP-TVGQLRAQLQGVLAKNPQ------LRHLSPQQ 4218
PQP KP V+Q P + G LR ++ +PQ L H SP Q
Sbjct: 1027 QPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQ 1086
Query: 4219 Q------QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTG 4272
Q Q+L+A + + Q V + P ++ P L P P
Sbjct: 1087 QNVQPKKQELRAASVVQP--QPLVVVKEEKIHSPIIRSEPFSPSLR--------PEPPKH 1136
Query: 4273 PLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSP------QEPKRPSQLPSP 4326
P PQ P P G P P PPP +P QEPK P +P
Sbjct: 1137 PESIKAPVHLPQRPEMKPVDVGRPVIRP---PEQNAPPPGAPDKDKQKQEPKTP---VAP 1190
Query: 4327 SSQLPTE-----AQLPPTHPGTP 4344
L + A L HP TP
Sbjct: 1191 KKDLKIKNMGSWASLVQKHPTTP 1213
Score = 42.7 bits (99), Expect = 0.010
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 17/89 (19%)
Query: 4880 KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTE 4939
K+ P E H + + ++Q AP P++P PPP PP P P +
Sbjct: 727 KKGHPGREQKKHHHHHHQ----QMQQAPAPVPQQPPPPPQ-------QPPPPP----PPQ 771
Query: 4940 PLAEPPVPSPLPLASSPESARPKPRARPP 4968
+PP P P P S P+ A P ++ PP
Sbjct: 772 QQQQPPPPPPPP--SMPQQAAPAMKSSPP 798
Score = 42.0 bits (97), Expect = 0.017
Identities = 32/107 (29%), Positives = 42/107 (39%), Gaps = 21/107 (19%)
Query: 4881 QESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEP 4940
Q+ P P PP Q Q PPP P PP P +PA + P P
Sbjct: 762 QQPPPPPPPQQ-------------QQQPPPP--PPPPSMPQQAAPAMKSSPPPFIATQVP 806
Query: 4941 LAEPPVP----SPLPLASSPESARPKPRARP--PEEGEDSRPPRLKK 4981
+ EP +P P+ + P P+P P P+ E S PP L +
Sbjct: 807 VLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQ 853
Score = 41.6 bits (96), Expect = 0.022
Identities = 30/115 (26%), Positives = 43/115 (37%), Gaps = 7/115 (6%)
Query: 4856 WLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPS 4915
+L+Q V P L + + S + P P PP H +V +Q PPP +P
Sbjct: 931 YLQQLQKVQPPTPLLPSVKVQS----QPPPPLPPPPHP---SVQQQLQQQPPPPPPPQPQ 983
Query: 4916 PPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970
PPP P P ++ T PP P P P P+ P++
Sbjct: 984 PPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQ 1038
Score = 40.4 bits (93), Expect = 0.049
Identities = 48/204 (23%), Positives = 76/204 (37%), Gaps = 27/204 (13%)
Query: 845 RPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSP--LLGEPALSE 902
R E P + P + + PP+ P P + P P P+++P ++ P ++
Sbjct: 183 RKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPF-PAVTPDLIVQTPVMTV 241
Query: 903 PGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFG 962
PL P +P P P+ +PQ + P PII A P ++ G
Sbjct: 242 VPPQPLQT-PPPVPPQPQPPPAPAPQPVQSHP------PIIAATPQP-------VKTKKG 287
Query: 963 AKGDSDPESPLAAPILETPISPPPEANCTD---------PEPVPPMILPPSPGSPVGPAS 1013
K +D +P + P S PPE T P P +P S P S
Sbjct: 288 VKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKS 347
Query: 1014 PILMEPLPPQCSPLLQHSLVPQNS 1037
+ E L CS +L+ +++
Sbjct: 348 SKVSEQL-KCCSGILKEMFAKKHA 370
Score = 38.9 bits (89), Expect = 0.14
Identities = 42/176 (23%), Positives = 61/176 (34%), Gaps = 24/176 (13%)
Query: 4812 PNSYEVLFPESPARAGT-------EPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVL 4864
P + P+ P+R +P + A P + L + P P + D
Sbjct: 859 PPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEP 918
Query: 4865 PGYTLKS---QLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPL 4921
P L S QL + L K + P P P+ V+ S PPP P PP +
Sbjct: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPS------------VKVQSQPPPPLPPPPHPSV 966
Query: 4922 APSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
P P P P + P P P+ P + PP +G+ +PP
Sbjct: 967 QQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQ--QPP 1020
Score = 38.5 bits (88), Expect = 0.19
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP-RARP 4967
PPP + +P P P T + +P +PL PP P P P + P+P ++ P
Sbjct: 215 PPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQP--QPPPAPAPQPVQSHP 272
Query: 4968 PEEGEDSRPPRLKKWKGVRWK 4988
P +P + K KGV+ K
Sbjct: 273 PIIAATPQPVKTK--KGVKRK 291
Score = 37.7 bits (86), Expect = 0.32
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 30/113 (26%)
Query: 2370 RPGSYTDPY----AQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPL 2425
+PG T P + PP T PQP PP P ++ P PF V Q+ + +
Sbjct: 190 KPGVSTVPNTTQASTPPQTQTPQPNPP------PVQATPH-PFPAVTPDLIVQTPVMTVV 242
Query: 2426 TPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVA 2478
P+PL Q+P PP PQ + P AP +P + PP +A
Sbjct: 243 PPQPL--------------QTP-----PPVPPQPQPPPAPAPQPVQSHPPIIA 276
Score = 37.7 bits (86), Expect = 0.32
Identities = 53/227 (23%), Positives = 79/227 (34%), Gaps = 21/227 (9%)
Query: 993 PEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP-----AL 1047
P PVP PP P P +P PP P S+ Q +P + SPP +
Sbjct: 750 PAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPP----SMPQQAAPAMKSSPPPFIATQV 805
Query: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPS 1107
P+ P + +G + LH + E P P +T P + +S PA
Sbjct: 806 PVLEPQLPGSVFDPIGHFTQPILHLPQPE--LPPHLPQPPEHSTPPHLNQHAVVSPPALH 863
Query: 1108 PA-PALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTP- 1165
A P P P P QTP + P +L +E P P
Sbjct: 864 NALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPL 923
Query: 1166 ----MEVYPECKQTAGQGSP----CEEQEEPRAPVAPTPPTLIKSDI 1204
M++Y + Q +P + Q +P P+ P P ++ +
Sbjct: 924 TSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQL 970
Score = 37.7 bits (86), Expect = 0.32
Identities = 50/219 (22%), Positives = 67/219 (30%), Gaps = 31/219 (14%)
Query: 2753 PSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPY-------P 2805
P L + S PS+ + PP PA P ++ Q Q + P P
Sbjct: 859 PPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEP 918
Query: 2806 GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPG 2865
+ PL Q QL+ QQ S + S P P L S + + P P
Sbjct: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPP 978
Query: 2866 EPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLA 2925
P P P Q Q PP+ P+ H P +G
Sbjct: 979 PPQPQPPPQQQH--------------------QPPPRPVHLQPMQFSTHIQQPPPPQGQQ 1018
Query: 2926 VSGLPPQKPSAPPAP----ELNNSLHPTPHTKGPTLPTG 2960
PP + PP P ++ H H K TG
Sbjct: 1019 PPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTG 1057
Score = 37.0 bits (84), Expect = 0.55
Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 17/101 (16%)
Query: 4878 LLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELP 4937
LL+ E P P PP T L ++QL + PP+PL PS + P
Sbjct: 912 LLEDEEP-PAPPL----TSMQMQLYLQQL------QKVQPPTPLLPSVK------VQSQP 954
Query: 4938 TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPR 4978
PL PP PS P P+ +PP + + PPR
Sbjct: 955 PPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR 995
Score = 36.2 bits (82), Expect = 0.93
Identities = 20/59 (33%), Positives = 23/59 (38%)
Query: 4297 STGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPP 4355
ST P P PPP P+ P Q P +PP TP P P +PPP
Sbjct: 203 STPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPP 261
Score = 36.2 bits (82), Expect = 0.93
Identities = 67/278 (24%), Positives = 100/278 (35%), Gaps = 38/278 (13%)
Query: 2116 PPPAAAPTIFIGS---PTTPAGLSTSADGFLK--PPAGSVPGPDSPGELFLKLPPQVPAQ 2170
PP P++ + S P P S L+ PP P P P + + PP+
Sbjct: 940 PPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHL 999
Query: 2171 VPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTP 2230
P Q + P + + P PP P P PA+P + H +
Sbjct: 1000 QPMQFSTHIQQPPPPQGQQPPHPP--PGQQPPPPQPAKPQQVIQHH-----HSPRHHKSD 1052
Query: 2231 PGTPRHQPSTPDPFL--KPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVK 2288
P + H P P + P+ +L +SP + + L + + + VK
Sbjct: 1053 PYSTGHLREAPSPLMIHSPQMSQFQSL-THQSPPQQNVQPKKQELRAASVVQPQPLVVVK 1111
Query: 2289 KEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPL-TPRASQVEPQSPGLGL 2347
+E++ SP + S L K P+ KAP+ P+ +++P G
Sbjct: 1112 EEKI--HSP--------IIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVG--- 1158
Query: 2348 RPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP 2385
RP PP Q AP PP PD D Q P TP
Sbjct: 1159 RPVIRPPEQN-AP-PPGAPD-------KDKQKQEPKTP 1187
Score = 35.0 bits (79), Expect = 2.1
Identities = 40/170 (23%), Positives = 57/170 (33%), Gaps = 9/170 (5%)
Query: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTG---PVLGPVHPTPPPSSPQEPKRPSQL 4323
PG T P + P PQ P PP +T P + P P P +P Q
Sbjct: 191 PGVSTVPNTTQASTP-PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQT 249
Query: 4324 PSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNL 4383
P P P P P P P P + + ADT + P P +L
Sbjct: 250 PPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSL 309
Query: 4384 AETQKPEQSSLVPGHLDQVNGQVVPEASQL-SIKQEPREEPCALGAQSVK 4432
PE + G + + V P + +Q P E + ++ +K
Sbjct: 310 ----PPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLK 355
Score = 34.7 bits (78), Expect = 2.7
Identities = 30/124 (24%), Positives = 48/124 (38%), Gaps = 24/124 (19%)
Query: 4882 ESPAPEPP----TQHSYTYNVSNLDVR---QLSAPPPEEPSPPPSPLAPSPASPPT---- 4930
++P P PP T H + +L V+ PP +PPP P P P P
Sbjct: 209 QTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPV 268
Query: 4931 ---EPLVELPTEPL---------AEPPVPSPLPLASSPESARPKPR-ARPPEEGEDSRPP 4977
P++ +P+ A+ P+ + P S P+P+ + + E SRP
Sbjct: 269 QSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPV 328
Query: 4978 RLKK 4981
+ K
Sbjct: 329 KPPK 332
Score = 34.7 bits (78), Expect = 2.7
Identities = 47/168 (27%), Positives = 63/168 (37%), Gaps = 43/168 (25%)
Query: 3272 PAQQQQQ-----------QQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGA 3320
P QQQQQ QQ ++ S+P P A +P P L GS +
Sbjct: 769 PPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV--LEPQLPGSVFD---PIGHF 823
Query: 3321 RQP--GLPQPLMPT---QPPAH---------------ALQQRLAPSMAMVSNQGHMLSGQ 3360
QP LPQP +P QPP H AL L + SN+ L +
Sbjct: 824 TQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPK 883
Query: 3361 HGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMK------PQQLAMQQQL 3402
+ P + P+L Q PM PP + ++ P +MQ QL
Sbjct: 884 PARPPAVSPALTQTPLLPQPPM-AQPPQVLLEDEEPPAPPLTSMQMQL 930
Score = 33.9 bits (76), Expect = 4.6
Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 8/68 (11%)
Query: 3250 EDLLEHEKK---ELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSL 3306
ED LE ++ E +++Q+ Q + QQQQQQQQ ++ +A P S P S+
Sbjct: 1266 EDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQ-----SM 1320
Query: 3307 AGSQQQLS 3314
Q++L+
Sbjct: 1321 LDQQRELA 1328
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 315,519,308
Number of Sequences: 37866
Number of extensions: 23559218
Number of successful extensions: 440565
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1551
Number of HSP's successfully gapped in prelim test: 3032
Number of HSP's that attempted gapping in prelim test: 93709
Number of HSP's gapped (non-prelim): 152719
length of query: 5537
length of database: 18,247,518
effective HSP length: 125
effective length of query: 5412
effective length of database: 13,514,268
effective search space: 73139218416
effective search space used: 73139218416
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 74 (33.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.