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Search of human proteins with 148596992
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148596992 heart alpha-kinase [Homo sapiens]
(2170 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148596992 heart alpha-kinase [Homo sapiens] 4366 0.0
gi|115511036 alpha-kinase 3 [Homo sapiens] 330 7e-90
gi|18921093 transient receptor potential cation channel, subfami... 76 3e-13
gi|148612863 transient receptor potential cation channel, subfam... 70 2e-11
gi|110349719 titin isoform N2-A [Homo sapiens] 64 2e-09
gi|110349717 titin isoform novex-2 [Homo sapiens] 64 2e-09
gi|110349713 titin isoform novex-1 [Homo sapiens] 64 2e-09
gi|110349715 titin isoform N2-B [Homo sapiens] 64 2e-09
gi|144226847 obscurin-like 1 [Homo sapiens] 63 3e-09
gi|110349721 titin isoform novex-3 [Homo sapiens] 58 1e-07
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 56 4e-07
gi|140560917 myomesin 1 isoform b [Homo sapiens] 55 7e-07
gi|140560919 myomesin 1 isoform a [Homo sapiens] 55 7e-07
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 54 1e-06
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 54 1e-06
gi|153792294 myopalladin [Homo sapiens] 54 1e-06
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 54 2e-06
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 54 2e-06
gi|157785645 SPEG complex locus [Homo sapiens] 53 4e-06
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 50 2e-05
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 50 2e-05
gi|9558749 elongation factor-2 kinase [Homo sapiens] 50 2e-05
gi|155969693 myomesin family, member 3 [Homo sapiens] 50 3e-05
gi|93102361 palladin [Homo sapiens] 49 4e-05
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 49 5e-05
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 49 5e-05
gi|44681484 cell division cycle associated 2 [Homo sapiens] 49 7e-05
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 48 9e-05
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 48 9e-05
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 48 9e-05
>gi|148596992 heart alpha-kinase [Homo sapiens]
Length = 2170
Score = 4366 bits (11324), Expect = 0.0
Identities = 2170/2170 (100%), Positives = 2170/2170 (100%)
Query: 1 MKDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISN 60
MKDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISN
Sbjct: 1 MKDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISN 60
Query: 61 YEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDD 120
YEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDD
Sbjct: 61 YEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDD 120
Query: 121 RDRGWKHETGTHEEERANQIDEKEHPYKEEESISPGTPRSADSSPSKSNHSLSLQSLGNL 180
RDRGWKHETGTHEEERANQIDEKEHPYKEEESISPGTPRSADSSPSKSNHSLSLQSLGNL
Sbjct: 121 RDRGWKHETGTHEEERANQIDEKEHPYKEEESISPGTPRSADSSPSKSNHSLSLQSLGNL 180
Query: 181 DISVSSSENPLGVKGTRHTGEAYDPSNTEEIANGLLFLNSSHIYEKQDRCCHKTVHSMAS 240
DISVSSSENPLGVKGTRHTGEAYDPSNTEEIANGLLFLNSSHIYEKQDRCCHKTVHSMAS
Sbjct: 181 DISVSSSENPLGVKGTRHTGEAYDPSNTEEIANGLLFLNSSHIYEKQDRCCHKTVHSMAS 240
Query: 241 KFTDGDLNNDGPHDEGLRSSQQNPKVQKYISFSLPLSEATAHIYPGDSAVANKQPSPQLS 300
KFTDGDLNNDGPHDEGLRSSQQNPKVQKYISFSLPLSEATAHIYPGDSAVANKQPSPQLS
Sbjct: 241 KFTDGDLNNDGPHDEGLRSSQQNPKVQKYISFSLPLSEATAHIYPGDSAVANKQPSPQLS 300
Query: 301 SEDSDSDYELCPEITLTYTEEFSDDDLEYLECSDVMTDYSNAVWQRNLLGTEHVFLLESD 360
SEDSDSDYELCPEITLTYTEEFSDDDLEYLECSDVMTDYSNAVWQRNLLGTEHVFLLESD
Sbjct: 301 SEDSDSDYELCPEITLTYTEEFSDDDLEYLECSDVMTDYSNAVWQRNLLGTEHVFLLESD 360
Query: 361 DEEMEFGEHCLGGCEHFLSGMGCGSRVSGDAGPMVATAGFCGHHSQPQEVGVRSSRVSKH 420
DEEMEFGEHCLGGCEHFLSGMGCGSRVSGDAGPMVATAGFCGHHSQPQEVGVRSSRVSKH
Sbjct: 361 DEEMEFGEHCLGGCEHFLSGMGCGSRVSGDAGPMVATAGFCGHHSQPQEVGVRSSRVSKH 420
Query: 421 GPSSPQTGMTLILGPHQDGTSSVTEQGRYKLPTAPEAAENDYPGIQGETRDSHQAREEFA 480
GPSSPQTGMTLILGPHQDGTSSVTEQGRYKLPTAPEAAENDYPGIQGETRDSHQAREEFA
Sbjct: 421 GPSSPQTGMTLILGPHQDGTSSVTEQGRYKLPTAPEAAENDYPGIQGETRDSHQAREEFA 480
Query: 481 SDNLLNMDESVRETEMKLLSGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVRQP 540
SDNLLNMDESVRETEMKLLSGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVRQP
Sbjct: 481 SDNLLNMDESVRETEMKLLSGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVRQP 540
Query: 541 GMKGNPKKPNANLRESTTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADAR 600
GMKGNPKKPNANLRESTTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADAR
Sbjct: 541 GMKGNPKKPNANLRESTTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADAR 600
Query: 601 ECAISTQAEQEAKTLQTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQET 660
ECAISTQAEQEAKTLQTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQET
Sbjct: 601 ECAISTQAEQEAKTLQTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQET 660
Query: 661 VRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHE 720
VRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHE
Sbjct: 661 VRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHE 720
Query: 721 EKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPE 780
EKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPE
Sbjct: 721 EKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPE 780
Query: 781 PTDTALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDT 840
PTDTALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDT
Sbjct: 781 PTDTALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDT 840
Query: 841 ELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISH 900
ELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISH
Sbjct: 841 ELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISH 900
Query: 901 TASEGATGENLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGG 960
TASEGATGENLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGG
Sbjct: 901 TASEGATGENLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGG 960
Query: 961 DKSPSPSAADTTATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIATEVHPA 1020
DKSPSPSAADTTATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIATEVHPA
Sbjct: 961 DKSPSPSAADTTATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIATEVHPA 1020
Query: 1021 KYLAVSIPEDKHAGGTEERFPRASHEKVSQFPSQVQLDHILSGATIKSTKELLCRAPSVP 1080
KYLAVSIPEDKHAGGTEERFPRASHEKVSQFPSQVQLDHILSGATIKSTKELLCRAPSVP
Sbjct: 1021 KYLAVSIPEDKHAGGTEERFPRASHEKVSQFPSQVQLDHILSGATIKSTKELLCRAPSVP 1080
Query: 1081 GVPHHVLQLPEGEGFCSNSPLQVDNLSGDKSQTVDRADFRSYEENFQERGSETKQGVQQQ 1140
GVPHHVLQLPEGEGFCSNSPLQVDNLSGDKSQTVDRADFRSYEENFQERGSETKQGVQQQ
Sbjct: 1081 GVPHHVLQLPEGEGFCSNSPLQVDNLSGDKSQTVDRADFRSYEENFQERGSETKQGVQQQ 1140
Query: 1141 SLSQQGSLSAPDFQQSLPTTSAAQEERNLVPTAHSPASSREGAGQRSGWGTRVSVVAETA 1200
SLSQQGSLSAPDFQQSLPTTSAAQEERNLVPTAHSPASSREGAGQRSGWGTRVSVVAETA
Sbjct: 1141 SLSQQGSLSAPDFQQSLPTTSAAQEERNLVPTAHSPASSREGAGQRSGWGTRVSVVAETA 1200
Query: 1201 GEEDSQALSNVPSLSDILLEESKEYRPGNWEAGNKLKIITLEASASEIWPPRQLTNSESK 1260
GEEDSQALSNVPSLSDILLEESKEYRPGNWEAGNKLKIITLEASASEIWPPRQLTNSESK
Sbjct: 1201 GEEDSQALSNVPSLSDILLEESKEYRPGNWEAGNKLKIITLEASASEIWPPRQLTNSESK 1260
Query: 1261 ASDGGLIIPDKVWAVPDSLKADAVVPELAPSEIAALAHSPEDAESALADSRESHKGEEPT 1320
ASDGGLIIPDKVWAVPDSLKADAVVPELAPSEIAALAHSPEDAESALADSRESHKGEEPT
Sbjct: 1261 ASDGGLIIPDKVWAVPDSLKADAVVPELAPSEIAALAHSPEDAESALADSRESHKGEEPT 1320
Query: 1321 ISVHWRSLSSRGFSQPRLLESSVDPVDEKELSVTDSLSAASETGGKENVNNVSQDQEEKQ 1380
ISVHWRSLSSRGFSQPRLLESSVDPVDEKELSVTDSLSAASETGGKENVNNVSQDQEEKQ
Sbjct: 1321 ISVHWRSLSSRGFSQPRLLESSVDPVDEKELSVTDSLSAASETGGKENVNNVSQDQEEKQ 1380
Query: 1381 LKMDHTAFFKKFLTCPKILESSVDPIDEISVIEYTRAGKPEPSETTPQGAREGGQSNDGN 1440
LKMDHTAFFKKFLTCPKILESSVDPIDEISVIEYTRAGKPEPSETTPQGAREGGQSNDGN
Sbjct: 1381 LKMDHTAFFKKFLTCPKILESSVDPIDEISVIEYTRAGKPEPSETTPQGAREGGQSNDGN 1440
Query: 1441 MGHEAEIQPAILQVPCLQGTILSENRISRSQEGSMKQEAEQIQPEEAKTAIWQVLQPSEG 1500
MGHEAEIQPAILQVPCLQGTILSENRISRSQEGSMKQEAEQIQPEEAKTAIWQVLQPSEG
Sbjct: 1441 MGHEAEIQPAILQVPCLQGTILSENRISRSQEGSMKQEAEQIQPEEAKTAIWQVLQPSEG 1500
Query: 1501 GERIPSGCSIGQIQESSDGSLGEAEQSKKDKAELISPTSPLSSCLPIMTHASLGVDTHNS 1560
GERIPSGCSIGQIQESSDGSLGEAEQSKKDKAELISPTSPLSSCLPIMTHASLGVDTHNS
Sbjct: 1501 GERIPSGCSIGQIQESSDGSLGEAEQSKKDKAELISPTSPLSSCLPIMTHASLGVDTHNS 1560
Query: 1561 TGQIHDVPENDIVEPRKRQYVFPVSQKRGTIENERGKPLPSSPDLTRFPCTSSPEGNVTD 1620
TGQIHDVPENDIVEPRKRQYVFPVSQKRGTIENERGKPLPSSPDLTRFPCTSSPEGNVTD
Sbjct: 1561 TGQIHDVPENDIVEPRKRQYVFPVSQKRGTIENERGKPLPSSPDLTRFPCTSSPEGNVTD 1620
Query: 1621 FLISHKMEEPKIEVLQIGETKPPSSSSSSAKTLAFISGERELEKAPKLLQDPCQKGTLGC 1680
FLISHKMEEPKIEVLQIGETKPPSSSSSSAKTLAFISGERELEKAPKLLQDPCQKGTLGC
Sbjct: 1621 FLISHKMEEPKIEVLQIGETKPPSSSSSSAKTLAFISGERELEKAPKLLQDPCQKGTLGC 1680
Query: 1681 AKKSREREKSLEARAGKSPGTLTAVTGSEEVKRKPEAPGSGHLAEGVKKKILSRVAALRL 1740
AKKSREREKSLEARAGKSPGTLTAVTGSEEVKRKPEAPGSGHLAEGVKKKILSRVAALRL
Sbjct: 1681 AKKSREREKSLEARAGKSPGTLTAVTGSEEVKRKPEAPGSGHLAEGVKKKILSRVAALRL 1740
Query: 1741 KLEEKENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEH 1800
KLEEKENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEH
Sbjct: 1741 KLEEKENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEH 1800
Query: 1801 SGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSAGDNSTVSFAIVQASPKDQGLYYCCI 1860
SGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSAGDNSTVSFAIVQASPKDQGLYYCCI
Sbjct: 1801 SGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSAGDNSTVSFAIVQASPKDQGLYYCCI 1860
Query: 1861 KNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIAT 1920
KNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIAT
Sbjct: 1861 KNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIAT 1920
Query: 1921 EELHFGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQ 1980
EELHFGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQ
Sbjct: 1921 EELHFGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQ 1980
Query: 1981 ECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKY 2040
ECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKY
Sbjct: 1981 ECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKY 2040
Query: 2041 SIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGY 2100
SIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGY
Sbjct: 2041 SIRDGKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGY 2100
Query: 2101 KGFKGNCSMTFIDQFKALHQCNKYCKMLGLKSLQNNNQKQKQPSIGKSKVQTNSMTIKKA 2160
KGFKGNCSMTFIDQFKALHQCNKYCKMLGLKSLQNNNQKQKQPSIGKSKVQTNSMTIKKA
Sbjct: 2101 KGFKGNCSMTFIDQFKALHQCNKYCKMLGLKSLQNNNQKQKQPSIGKSKVQTNSMTIKKA 2160
Query: 2161 GPETPGEKKT 2170
GPETPGEKKT
Sbjct: 2161 GPETPGEKKT 2170
>gi|115511036 alpha-kinase 3 [Homo sapiens]
Length = 1907
Score = 330 bits (847), Expect = 7e-90
Identities = 199/509 (39%), Positives = 286/509 (56%), Gaps = 20/509 (3%)
Query: 1681 AKKSREREKSLEARAGKS--PGTLTAVTGSEEVKRKPEAPGS-GHLAEGVKKKILSRVAA 1737
A++ R K A G++ P + T S RK PGS G + R A+
Sbjct: 1365 ARRKRFLPKVRAAGDGEATTPEERESPTVSPRGPRKSLVPGSPGTPGRERRSPTQGRKAS 1424
Query: 1738 -LRLKLEEKENIRKNSAFLKKMPKLETSLSHTEEKQDP--KKPSCKREGRAPVLLKKIQA 1794
L + E+E + K L+T ++ E KQ+ K K +AP +++KI+
Sbjct: 1425 MLEVPRAEEELAAGDLGPSPKAGGLDTEVALDEGKQETLAKPRKAKDLLKAPQVIRKIRV 1484
Query: 1795 EMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSAGDNSTVSFAIVQASPKDQG 1854
E FP+ SG++KL CQF I DS + W KD + + +V RSAGD + AIVQASP D G
Sbjct: 1485 EQFPDASGSLKLWCQFFNILSDSVLTWAKDQRPVGEVGRSAGDEGPAALAIVQASPVDCG 1544
Query: 1855 LYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRL 1914
+Y C I N +G + +F L+ EVL SR++ + EEIE + ++F + +G +L
Sbjct: 1545 VYRCTIHNEHGSASTDFCLSPEVLSGFISREEGEVGEEIEMTPMVFAKGLADSGCWGDKL 1604
Query: 1915 RGQIATEELH---FGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELI 1971
G++ +EEL +G G+ RKA ++ V++GL P+F+ G C++KV + + +G + L+
Sbjct: 1605 FGRLVSEELRGGGYGCGL-RKASQAKVIYGLEPIFESGRTCIIKVSSLLVFGPSSETSLV 1663
Query: 1972 QRNYKLAAQECYVQNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEE 2031
RNY + Q C +QN +R Y KI+AAEA+ GFGEVPEIIP++LI+RP NNIPYAT+EE
Sbjct: 1664 GRNYDVTIQGCKIQNMSREYCKIFAAEARAAPGFGEVPEIIPLYLIYRPANNIPYATLEE 1723
Query: 2032 ELIGEFVKYSIRDG--KEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLT 2089
+L Y R+ E SEA QKC TFQHW+YQ T+G LVTD+ GV K+T
Sbjct: 1724 DLGKPLESYCSREWGCAEAPTASGSSEAMQKCQTFQHWLYQWTNGSFLVTDLAGVDWKMT 1783
Query: 2090 DVGIATLAKGYKGFKGNCSMTFIDQFKALHQCNKYCKMLGLKSL--------QNNNQKQK 2141
DV IAT +GY+G K +C +D+F + HQCN YC++LGL L Q + K
Sbjct: 1784 DVQIATKLRGYQGLKESCFPALLDRFASSHQCNAYCELLGLTPLKGPEAAHPQAKAKGSK 1843
Query: 2142 QPSIGKSKVQTNSMTIKKAGPETPGEKKT 2170
PS G+ Q + KK P G +K+
Sbjct: 1844 SPSAGRKGSQLSPQPQKKGLPSPQGTRKS 1872
Score = 80.9 bits (198), Expect = 1e-14
Identities = 41/96 (42%), Positives = 56/96 (58%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F +TL S+ V E SD CI++G P+PEVTWYK+ +D + YE H L
Sbjct: 281 FETTLKSRSVSEDSDVRFTCIVTGYPEPEVTWYKDDTELDRYCGLPKYEITHQGNRHTLQ 340
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
L C + DAA+YQ SA+NS G++ CS +EV +E
Sbjct: 341 LYRCREEDAAIYQASAQNSKGIVSCSGVLEVGTMTE 376
>gi|18921093 transient receptor potential cation channel, subfamily M,
member 6 [Homo sapiens]
Length = 2022
Score = 76.3 bits (186), Expect = 3e-13
Identities = 67/248 (27%), Positives = 101/248 (40%), Gaps = 16/248 (6%)
Query: 1927 EGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYVQN 1986
+G RKA R + KPG ++K + + R ++ Q + L +Q
Sbjct: 1776 DGGLRKAMRVVSTWSEDDILKPGQVFIVK--SFLPEVVRTWHKIFQESTVLHLCLREIQQ 1833
Query: 1987 TARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRDGK 2046
IY + P + +FLI+ N + T+E+ + GEF KY+ +G
Sbjct: 1834 QRAAQKLIYTFNQVKPQTIPYTPRFLEVFLIYCHSAN-QWLTIEKYMTGEFRKYNNNNGD 1892
Query: 2047 EINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGI----ATLAKGYKG 2102
EI E F HW Y+ T G LLV D+QGVG LTD + ++G
Sbjct: 1893 EITPTNTLEEL---MLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEVKQSRGMVF 1949
Query: 2103 FKGNCSMTFIDQFKALHQCNKYCKMLGLKSLQNNNQKQKQPSIGKSKVQTNSMTIKKAGP 2162
N I F A H CN C+ L L L+ N+ ++ + T + IK
Sbjct: 1950 GPANLGEDAIRNFIAKHHCNSCCRKLKLPDLKRNDYSPERIN------STFGLEIKIESA 2003
Query: 2163 ETPGEKKT 2170
E P ++T
Sbjct: 2004 EEPPARET 2011
>gi|148612863 transient receptor potential cation channel, subfamily
M, member 7 [Homo sapiens]
Length = 1865
Score = 70.1 bits (170), Expect = 2e-11
Identities = 48/138 (34%), Positives = 65/138 (47%), Gaps = 18/138 (13%)
Query: 2009 PEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRDGKEINFLRRESEAGQKCCTFQHWV 2068
P + +FL++ +A VEE + GEF KY+ +G EI E F HW
Sbjct: 1700 PRFLEVFLLYCHSAGQWFA-VEECMTGEFRKYNNNNGDEIIPTNTLEEI---MLAFSHWT 1755
Query: 2069 YQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFKGNCSMTF---------IDQFKALH 2119
Y+ T G LLV D+QGVG LTD + + K +C M F I F+A H
Sbjct: 1756 YEYTRGELLVLDLQGVGENLTDPSVIKAEE-----KRSCDMVFGPANLGEDAIKNFRAKH 1810
Query: 2120 QCNKYCKMLGLKSLQNNN 2137
CN C+ L L L+ N+
Sbjct: 1811 HCNSCCRKLKLPDLKRND 1828
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 63.5 bits (153), Expect = 2e-09
Identities = 35/92 (38%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F L + V +S+A L C ++G PKP V WY+ G+ I G+ + F+ Y H L
Sbjct: 30930 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGY-HQLI 30988
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
++ T +DA VYQ+ A N G + +AS+EVE
Sbjct: 30989 IASVTDDDATVYQVRATNQGGSVSGTASLEVE 31020
Score = 62.0 bits (149), Expect = 6e-09
Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F+S SQ + E + + C ISG+P PE+ W+KN I I SN ++ ++ L
Sbjct: 33136 FISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI---SISSNVSISRSRNVYSLE 33192
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETGTHE 133
+ + +D+ Y I AKN G +AS+ V E P L D + +
Sbjct: 33193 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQS 33252
Query: 134 EERANQIDEKEHPYKEEESISPGTPRSADSSPSKSNHSLSLQSLGNLD---ISVSSS 187
+ + K+E S S + SA S S+S QS+ ++ + +SSS
Sbjct: 33253 VQMSAS--------KQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSS 33301
Score = 52.8 bits (125), Expect = 4e-06
Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 6/111 (5%)
Query: 9 RPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY 68
+ P F+ L +V + SD L C ++G P EVTW KN + I S Y +
Sbjct: 4952 KEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSS---KKYTLTDRVS 5008
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLED 119
+ LH++ C +D YQ N G CS V ++ E P +E+
Sbjct: 5009 VFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK---EPPSFIKKIEN 5056
Score = 49.7 bits (117), Expect = 3e-05
Identities = 24/70 (34%), Positives = 38/70 (54%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
I+ P+P VTWYK+GQ I Y F ++ ++ L ++ T +D A Y + A+N +G
Sbjct: 31713 ITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG 31772
Query: 95 MICCSASVEV 104
C A + V
Sbjct: 31773 EDSCKAKLTV 31782
Score = 47.8 bits (112), Expect = 1e-04
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 8/111 (7%)
Query: 22 KVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY--IHVLHLSCCTK 79
+V E A RC ++G P+P+V WY NGQ +I + F +Y IH L + C
Sbjct: 1851 RVLEGETARFRCRVTGYPQPKVNWYLNGQ------LIRKSKRFRVRYDGIHYLDIVDCKS 1904
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETG 130
D +++A+N G+I +E++ + + + R HE G
Sbjct: 1905 YDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPG 1955
Score = 47.8 bits (112), Expect = 1e-04
Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query: 34 IISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSF 93
+ISG+P+P+++WYK Q + +F + + L L DAAVY AKN +
Sbjct: 3261 VISGRPQPKISWYKEEQLLSTG---FKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDY 3317
Query: 94 GMICCSASVEVE 105
G+ SAS+ VE
Sbjct: 3318 GVATTSASLSVE 3329
Score = 46.2 bits (108), Expect = 3e-04
Identities = 30/92 (32%), Positives = 39/92 (42%), Gaps = 3/92 (3%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P FLS S A C ++G P E W K+G A+ S N+ + + H
Sbjct: 3550 PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPS---PNWRISDAENKH 3606
Query: 71 VLHLSCCTKNDAAVYQISAKNSFGMICCSASV 102
+L LS T D VY A N FG C A +
Sbjct: 3607 ILELSNLTIQDRGVYSCKASNKFGADICQAEL 3638
Score = 45.4 bits (106), Expect = 6e-04
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 3/98 (3%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S V EK L C+++G P+ +V W K+G+ I S S FEN + + K
Sbjct: 5149 SVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFS--MSFENN-VASFRIQSVMK 5205
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNL 117
D+ Y +N FG C A + V + P + L
Sbjct: 5206 QDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKL 5243
Score = 44.7 bits (104), Expect = 0.001
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAK 90
L C ++G P+ V WYK+G+ + S ++F I L + + DA Y +
Sbjct: 5723 LECKVAGTPELSVEWYKDGKLLTSS---QKHKFSFYNKISSLRILSVERQDAGTYTFQVQ 5779
Query: 91 NSFGMICCSASVEVECSSENPQLSPNLED 119
N+ G C+A V+V + P + L++
Sbjct: 5780 NNVGKSSCTAVVDVSDRAVPPSFTRRLKN 5808
Score = 44.7 bits (104), Expect = 0.001
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAK 90
L C+++G P+ W+K+G+ + ++ F N+ + L + C +D +Y K
Sbjct: 6664 LECVVTGTPELSAKWFKDGRELSADS--KHHITFINK-VASLKIPCAEMSDKGLYSFEVK 6720
Query: 91 NSFGMICCSASVEVECSSENPQLSPNLED 119
NS G C+ SV V P L+D
Sbjct: 6721 NSVGKSNCTVSVHVSDRIVPPSFIRKLKD 6749
Score = 44.7 bits (104), Expect = 0.001
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 1762 ETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICW 1821
+T+ S K +PK P + PV++ +Q S +V A T W
Sbjct: 32830 KTTESTVTRKTEPKAP--EPISSKPVIVTGLQDTTVS--SDSVAKFAVKATGEPRPTAIW 32885
Query: 1822 TKDSKSIAQ--VQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLK 1879
TKD K+I Q + + D I + D GLY C +KNS G V++ LT + +K
Sbjct: 32886 TKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 32945
Query: 1880 QLSSRQ 1885
+++
Sbjct: 32946 DTEAQK 32951
Score = 44.3 bits (103), Expect = 0.001
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 27 SDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQ 86
SD +L+C ISG P EV W K+ + + S ++ + LH+ +D Y
Sbjct: 6473 SDVILQCEISGTPPFEVVWVKDRKQVRNS---KKFKITSKHFDTSLHILNLEASDVGEYH 6529
Query: 87 ISAKNSFGMICCSASVEVECSSENPQLSPNLED 119
A N G CS SV+ + E P+ L D
Sbjct: 6530 CKATNEVGSDTCSCSVKFK---EPPRFVKKLSD 6559
Score = 43.9 bits (102), Expect = 0.002
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F L S V E S A ISG P PEV+W+++GQ I S + F + L
Sbjct: 8 FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK-LT 66
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLE 118
+ TK ++ Y + A N G +A + V+ + P L+
Sbjct: 67 IPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ 111
Score = 42.7 bits (99), Expect = 0.004
Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 4/105 (3%)
Query: 5 EGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
E P PP +S L + V E L C ISG P P VTWY+ I+ S +++
Sbjct: 937 EIPVTPPT-LVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESS---IDFQIT 992
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
I L + D+ + SA N G + S + V+ S E
Sbjct: 993 FQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 1037
Score = 42.7 bits (99), Expect = 0.004
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 4/84 (4%)
Query: 8 QRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
+ PP+ F L Q V E + AVL C +S + +V W+KNG I S YE +
Sbjct: 12281 KEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKS---KKYEIVADG 12336
Query: 68 YIHVLHLSCCTKNDAAVYQISAKN 91
+ L + CT D Y AK+
Sbjct: 12337 RVRKLVIHDCTPEDIKTYTCDAKD 12360
Score = 42.4 bits (98), Expect = 0.005
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 2/109 (1%)
Query: 2 KDSEGPQRPPL-CFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISN 60
++ GP P F++ + QK+ E V C + G PKP V W K+G + +G
Sbjct: 1071 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT-TGYRYK 1129
Query: 61 YEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
+ + L +S +DA Y I +N G SAS+ E E
Sbjct: 1130 VSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1178
Score = 42.4 bits (98), Expect = 0.005
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
SQ V + SDA R + G+P PE WYKNG I+ S I Y ++ + L + T
Sbjct: 2086 SQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI--YWYWPEDNVCELVIRDVTA 2143
Query: 80 NDAAVYQISAKNSFG 94
D+A + A N G
Sbjct: 2144 EDSASIMVKAINIAG 2158
Score = 42.0 bits (97), Expect = 0.007
Identities = 47/195 (24%), Positives = 79/195 (40%), Gaps = 31/195 (15%)
Query: 1699 PGTLTAVTGSEEVK----RKPEAPGSGHLAEGVKKKILSRVAALRLKLEEKENIRKNSAF 1754
PG +T V + KPE+ G KI V ++ K EK +
Sbjct: 25299 PGRVTLVDVTRNTATIKWEKPESDGGS--------KITGYVVEMQTKGSEKWS---TCTQ 25347
Query: 1755 LKKMPKLETSLSHTEE------KQDPKKPSCKREGRAPVLLKKIQAEM---FPEHSGNVK 1805
+K + + L+ EE + K S R+ PV+ + I+ + P H+ NVK
Sbjct: 25348 VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVK 25407
Query: 1806 LSCQFA-----EIHEDSTICWTKDSKSIAQVQRS--AGDNSTVSFAIVQASPKDQGLYYC 1858
Q + +T+ W KD +++ + R + + S +I +AS +D G Y
Sbjct: 25408 AREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYEL 25467
Query: 1859 CIKNSYGKVTAEFNL 1873
C+ NS G +T +
Sbjct: 25468 CVSNSAGSITVPITI 25482
Score = 41.2 bits (95), Expect = 0.011
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 3/100 (3%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S KV L C ++G P+ W+K+G+ + + Y+ + L +
Sbjct: 7594 SIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSD---NKYKISFFNKVSGLKIINVAP 7650
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLED 119
+D+ VY +N G C+AS++V + P + L++
Sbjct: 7651 SDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKE 7690
Score = 40.8 bits (94), Expect = 0.015
Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 3/109 (2%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P F+ L KV A L+C ++G P+ V+WYK + + + Y+ +
Sbjct: 7960 PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPT---TTYKMHFRNNVA 8016
Query: 71 VLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLED 119
L + ND+ Y A+NS G + S + V+ P S L D
Sbjct: 8017 TLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRD 8065
Score = 40.4 bits (93), Expect = 0.019
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 9 RPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY 68
+ P F+ TL + ++A+L+C +SG E++W+K+ + I S Y F +
Sbjct: 3828 KEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSS---KKYRLFSQKS 3884
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFGMICCSAS 101
+ L + D Y+ N G C A+
Sbjct: 3885 LVCLEIFSFNSADVGEYECVVANEVGKCGCMAT 3917
Score = 40.0 bits (92), Expect = 0.025
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S + + ++ E C +SG P P++ WYK+G+ I G +F ++ L
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGRAS-LR 1350
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE--NPQLSPNLE 118
+ D +Y A N G CS + VE ++ P P LE
Sbjct: 1351 IPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLE 1397
Score = 40.0 bits (92), Expect = 0.025
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF-ENQYIHVL 72
F L + + E +SG P P + W K+GQ + + N E E + L
Sbjct: 31797 FKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLS---LGPNIEIIHEGLDYYAL 31853
Query: 73 HLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
H+ D Y+++A N+ G C A ++VE
Sbjct: 31854 HIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 31886
Score = 39.7 bits (91), Expect = 0.033
Identities = 25/98 (25%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 9 RPPLCFLSTLLSQKVPEKSDAV-LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
+ P F+ L + KV ++ +++ L C ISG P+ +V+W++N + S Y
Sbjct: 6361 KEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESW---KYNMSFIN 6417
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
+ +L ++ + D+ Y A N G CS ++ V+
Sbjct: 6418 SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455
Score = 39.7 bits (91), Expect = 0.033
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P F+ L Q V E DAV C +S + K V WY+NG+ I Y+F ++ IH
Sbjct: 12822 PTEFVEHLEDQTVTEFDDAVFSCQLSRE-KANVKWYRNGREIKEG---KKYKFEKDGSIH 12877
Query: 71 VLHLSCCTKNDAAVY 85
L + C +D Y
Sbjct: 12878 RLIIKDCRLDDECEY 12892
Score = 39.7 bits (91), Expect = 0.033
Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 5/87 (5%)
Query: 21 QKVPEKSDAVLRCII--SGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCT 78
Q SD+V + + +G+P+P W K+G+AI G Y+ E++ L +
Sbjct: 32859 QDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGG---KYKLSEDKGGFFLEIHKTD 32915
Query: 79 KNDAAVYQISAKNSFGMICCSASVEVE 105
+D+ +Y + KNS G + S + ++
Sbjct: 32916 TSDSGLYTCTVKNSAGSVSSSCKLTIK 32942
Score = 39.3 bits (90), Expect = 0.042
Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 6/90 (6%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A L C + G P +VTW+KN + + S + Y F N +L ++ D+ Y
Sbjct: 3755 ARLHCKLKGSPVIQVTWFKNNKELSESNTVRMY--FVNSEA-ILDITDVKVEDSGSYSCE 3811
Query: 89 AKNSFGMICCSASVEVECSSENPQLSPNLE 118
A N G CS + ++ E P LE
Sbjct: 3812 AVNDVGSDSCSTEIVIK---EPPSFIKTLE 3838
Score = 39.3 bits (90), Expect = 0.042
Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 4/98 (4%)
Query: 9 RPPLCFLSTLLSQKVPEKSDAV-LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
+ P F+ L ++ +K DA L C ++G P ++TW+ N + I S S + +
Sbjct: 4296 KEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKES---SKHRMSFVE 4352
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
VL L+ D+ Y A+N G CS+ V V+
Sbjct: 4353 STAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVK 4390
Score = 38.5 bits (88), Expect = 0.072
Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Query: 25 EKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAV 84
+ ++ L C +SG P EV WYK+ + + S Y+ + +H+ +D
Sbjct: 5530 KNAEVSLECELSGTPPFEVVWYKDKRQLRSS---KKYKIASKNFHTSIHILNVDTSDIGE 5586
Query: 85 YQISAKNSFGMICCSASVEVE 105
Y A+N G C +V+++
Sbjct: 5587 YHCKAQNEVGSDTCVCTVKLK 5607
Score = 38.5 bits (88), Expect = 0.072
Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAK 90
++ ++ G+P P VTW+K+G I+ N E + L + T++ VY + AK
Sbjct: 27978 IKALVQGRPVPRVTWFKDGVEIEKR---MNMEITDVLGSTSLFVRDATRDHRGVYTVEAK 28034
Query: 91 NSFGMICCSASVEVE 105
N+ G V+V+
Sbjct: 28035 NASGSAKAEIKVKVQ 28049
Score = 37.4 bits (85), Expect = 0.16
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 3/75 (4%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAK 90
L CI++G + W+K+ Q I S Y+F + L +S D+ Y SA
Sbjct: 4694 LECIVAGSHPISIQWFKDDQEISAS---EKYKFSFHDNTAFLEISQLEGTDSGTYTCSAT 4750
Query: 91 NSFGMICCSASVEVE 105
N G CS + V+
Sbjct: 4751 NKAGHNQCSGHLTVK 4765
Score = 37.4 bits (85), Expect = 0.16
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P F+ L + VL C +SG V W+++G I SG F EN +
Sbjct: 6740 PPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEI-VSGPKCQSSFSEN--VC 6796
Query: 71 VLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
L+LS +D +Y A N G CSA + V+
Sbjct: 6797 TLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 6831
Score = 37.4 bits (85), Expect = 0.16
Identities = 19/79 (24%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 27 SDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQ 86
+D L C + G P V+WYK+ + + Y+ ++ +H+ D YQ
Sbjct: 7414 ADVHLECELQGTPPFHVSWYKDKRELRSG---KKYKIMSENFLTSIHILNVDAADIGEYQ 7470
Query: 87 ISAKNSFGMICCSASVEVE 105
A N G C S+ ++
Sbjct: 7471 CKATNDVGSDTCVGSIALK 7489
Score = 37.4 bits (85), Expect = 0.16
Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A L C I G+P P++ WY+ G+ + S Y+ + H L + + D VY
Sbjct: 30550 AQLSCQIVGRPLPDIKWYRFGKELIQS---RKYKMSSDGRTHTLTVMTEEQEDEGVYTCI 30606
Query: 89 AKNSFGMICCSASVEVECSSENPQLSP 115
A N G + S+ + ++ + PQ P
Sbjct: 30607 ATNEVGEVETSSKLLLQAT---PQFHP 30630
Score = 37.4 bits (85), Expect = 0.16
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S V E A C G+P P VTW + GQ + S + ++ +Y +S
Sbjct: 32569 SMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTS---ARHQVTTTKYKSTFEISSVQA 32625
Query: 80 NDAAVYQISAKNSFG 94
+D Y + +NS G
Sbjct: 32626 SDEGNYSVVVENSEG 32640
Score = 37.0 bits (84), Expect = 0.21
Identities = 22/96 (22%), Positives = 38/96 (39%), Gaps = 3/96 (3%)
Query: 9 RPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY 68
+ P +S V + A L+ SG + W+K+GQ + + S Y+
Sbjct: 4576 KEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELT---LGSKYKISVTDT 4632
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+ +L + K D+ Y +N G C A + V
Sbjct: 4633 VSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINV 4668
Score = 37.0 bits (84), Expect = 0.21
Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 11 PLCFLSTLLSQKVPEKSDAV-LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYI 69
P F+ L + K+ + D+ L C I+G P+ V W++N + S Y +
Sbjct: 5422 PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPAS---DKYRMTFIDSV 5478
Query: 70 HVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
V+ ++ + D+ + A+N G CS V V+
Sbjct: 5479 AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 5514
Score = 37.0 bits (84), Expect = 0.21
Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 27 SDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQ 86
SD VL + G+P+P++ W K + +D +S ++ + V+ C ++D+ Y
Sbjct: 29063 SDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS-LQYTGKRATAVIKF--CDRSDSGKYT 29119
Query: 87 ISAKNSFGMICCSASVEV 104
++ KN+ G S V+V
Sbjct: 29120 LTVKNASGTKAVSVMVKV 29137
Score = 37.0 bits (84), Expect = 0.21
Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 36 SGQPKPEVTWYKNGQAIDGSGIISNYE-FFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
SG+P P +TW K ID +G +Y+ + ++ + + DA Y + AKN FG
Sbjct: 31052 SGKPDPVITWQKGQDLIDNNG---HYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 31108
Query: 95 MICCSASVEVECSSENP---QLSPNLEDDRDRGWKHETGTHEEERANQIDEK 143
+ + ++V + P ++S D + W + N I EK
Sbjct: 31109 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEK 31160
Score = 36.6 bits (83), Expect = 0.28
Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1786 PVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSA--GDNSTVSF 1843
P +L+++Q SG C I W K+ + ++ + D +
Sbjct: 3239 PQVLQELQPVTV--QSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 1844 AIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQD 1886
+++A P+D +Y C KN YG T +L+ EV + +S Q+
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3339
Score = 36.6 bits (83), Expect = 0.28
Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 22 KVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKND 81
+V ++ D +L ++G P E+TW+K+ + Y+ F ++ L + D
Sbjct: 4403 EVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSG---RKYKTFIQDHLVSLQILKFVAAD 4459
Query: 82 AAVYQISAKNSFGMICCSASV 102
A YQ N G CSA V
Sbjct: 4460 AGEYQCRVTNEVGSSICSARV 4480
Score = 36.6 bits (83), Expect = 0.28
Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
+ G+PKP VTW K Q + + + N+E I L+++ C ++D+ Y ++A+N G
Sbjct: 21089 VLGRPKPTVTWKKGDQILKQTQRV-NFETTATSTI--LNINECVRSDSGPYPLTARNIVG 21145
Query: 95 MICCSASVEV 104
+ +++V
Sbjct: 21146 EVGDVITIQV 21155
Score = 36.2 bits (82), Expect = 0.36
Identities = 22/74 (29%), Positives = 31/74 (41%), Gaps = 3/74 (4%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAK 90
L C + K VTW K+GQ + +Y+ I L + D+ Y +A
Sbjct: 3663 LECQVDEDRKVTVTWSKDGQKLPPG---KDYKICFEDKIATLEIPLAKLKDSGTYVCTAS 3719
Query: 91 NSFGMICCSASVEV 104
N G CSA+V V
Sbjct: 3720 NEAGSSSCSATVTV 3733
Score = 36.2 bits (82), Expect = 0.36
Identities = 27/100 (27%), Positives = 41/100 (41%), Gaps = 3/100 (3%)
Query: 6 GPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFE 65
G Q PP S+ V + C I G P+ +V WYK+ I S S +
Sbjct: 7300 GVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQES---SKFRMSF 7356
Query: 66 NQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
+ VL + + D+ Y A N+ G S S++V+
Sbjct: 7357 VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396
Score = 36.2 bits (82), Expect = 0.36
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 7/88 (7%)
Query: 19 LSQKVPEKSDAVLRCIIS--GQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSC 76
L + V ++ A LR ++S G+P P +TW K G + II E + +L +
Sbjct: 29452 LKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYS-----LLIVDK 29506
Query: 77 CTKNDAAVYQISAKNSFGMICCSASVEV 104
+ DA Y I A+N G + V+V
Sbjct: 29507 VNRYDAGKYTIEAENQSGKKSATVLVKV 29534
Score = 35.8 bits (81), Expect = 0.47
Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 10/151 (6%)
Query: 32 RCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKN 91
+C ++G ++TW K+ + I G NY+ + L + K DA Y A N
Sbjct: 7232 KCHVTGTAPIKITWAKDNREIRPGG---NYKMTLVENTATLTVLKVGKGDAGQYTCYASN 7288
Query: 92 SFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEE 151
G CSA + V+ E P+ LE R + E +E + + K YK+E
Sbjct: 7289 IAGKDSCSAQLGVQ---EPPRFIKKLEPSRIVK-QDEFTRYECKIGGSPEIKVLWYKDET 7344
Query: 152 SISPGTP---RSADSSPSKSNHSLSLQSLGN 179
I + DS H+LS++ G+
Sbjct: 7345 EIQESSKFRMSFVDSVAVLEMHNLSVEDSGD 7375
Score = 35.8 bits (81), Expect = 0.47
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 12/142 (8%)
Query: 12 LCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKN--GQAIDGSGIISNYEFFENQYI 69
L F+S S +V EK+ A + G P P V W K Q G + + + E +
Sbjct: 8454 LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAK-- 8511
Query: 70 HVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHET 129
L + TK D+ +Y+ A N G I + +++V+ + ++ +L + +
Sbjct: 8512 --LEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILKK 8569
Query: 130 GTHEEERAN------QIDEKEH 145
G EEE + +D KE+
Sbjct: 8570 GAGEEEEIDIMELLKNVDPKEY 8591
Score = 35.8 bits (81), Expect = 0.47
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 28 DAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQI 87
D + + G+P+P ++W K+G+ + + + N E E VLH+ K+D Y +
Sbjct: 24328 DLKIEIPVIGRPRPNISWVKDGEPLKQTTRV-NVE--ETATSTVLHIKEGNKDDFGKYTV 24384
Query: 88 SAKNSFGMICCSASVEV 104
+A NS G + SV V
Sbjct: 24385 TATNSAGTATENLSVIV 24401
Score = 35.4 bits (80), Expect = 0.61
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 10/95 (10%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYI 69
P LC+L+ E S+ L+ I G+P P V+W K + +S N +
Sbjct: 19988 PDLCYLAK-------ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTL 20040
Query: 70 HVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
V C K+DA Y I+ KN G + S++V
Sbjct: 20041 IVYD---CQKSDAGKYTITLKNVAGTKEGTISIKV 20072
Score = 35.4 bits (80), Expect = 0.61
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFEN--QYIHVLHLSCCTKNDAAVYQIS 88
L + G+P P +TW+ + + S I+ EN Y H++ + K A Y++
Sbjct: 30648 LHVMYIGRPVPAMTWFHGQKLLQNSENIT----IENTEHYTHLVMKNVQRKTHAGKYKVQ 30703
Query: 89 AKNSFGMICCSASVEVECSSENP 111
N FG + VE++ + P
Sbjct: 30704 LSNVFGTVDAILDVEIQDKPDKP 30726
Score = 35.4 bits (80), Expect = 0.61
Identities = 20/82 (24%), Positives = 34/82 (41%), Gaps = 1/82 (1%)
Query: 23 VPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDA 82
+ E + C +G+P PEVTW G+ I S + + L + K D
Sbjct: 33340 IDEGKVLTVACAFTGEPTPEVTWSCGGRKIH-SQEQGRFHIENTDDLTTLIIMDVQKQDG 33398
Query: 83 AVYQISAKNSFGMICCSASVEV 104
+Y +S N FG + ++ +
Sbjct: 33399 GLYTLSLGNEFGSDSATVNIHI 33420
Score = 35.0 bits (79), Expect = 0.80
Identities = 21/91 (23%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A L+C + G P+ ++WYK + + Y+ + L ++ +D Y
Sbjct: 7037 ATLQCKVDGTPEIRISWYKEHTKLRSA---PAYKMQFKNNVASLVINKVDHSDVGEYSCK 7093
Query: 89 AKNSFGMICCSASVEVECSSENPQLSPNLED 119
A NS G + SA + ++ P + L+D
Sbjct: 7094 ADNSVGAVASSAVLVIKARKLPPFFARKLKD 7124
Score = 35.0 bits (79), Expect = 0.80
Identities = 23/94 (24%), Positives = 36/94 (38%), Gaps = 3/94 (3%)
Query: 9 RPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY 68
+ P F+ L + + +L +G P VTW KNG + S +
Sbjct: 7865 KAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPS---QRCNITTTEK 7921
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFGMICCSASV 102
+L + T DA Y +N+ G CSA +
Sbjct: 7922 SAILEIPSSTVEDAGQYNCYIENASGKDSCSAQI 7955
Score = 35.0 bits (79), Expect = 0.80
Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 17/159 (10%)
Query: 7 PQRPPLCFLSTLLSQKVPEKSDAVLR--CIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
PQ PP L + + + LR +++G+P P W K +D ++ +
Sbjct: 15098 PQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 15157
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV-ECSSENPQLSP-------- 115
+++ I + + D Y I+A NS G +A VEV + L P
Sbjct: 15158 KSELI----IKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 15213
Query: 116 --NLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEES 152
N D D G TG E + ++ P + E S
Sbjct: 15214 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERS 15252
Score = 34.7 bits (78), Expect = 1.0
Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 3/83 (3%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
++G V WYKN I + SN E VL + NDA +Y N G
Sbjct: 8273 VAGSQPITVAWYKNNIEIQPT---SNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAG 8329
Query: 95 MICCSASVEVECSSENPQLSPNL 117
C++S+ ++ + P +L
Sbjct: 8330 SALCTSSIVIKEPKKPPVFDQHL 8352
Score = 34.7 bits (78), Expect = 1.0
Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 4/101 (3%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S V D + ISG+PKP +TW K+G + + I+ + + + L + K
Sbjct: 23238 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD---LTTLSIKETHK 23294
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDD 120
+D Y I+ N G S + V +P P DD
Sbjct: 23295 DDGGQYGITVANVVGQKTASIEI-VTLDKPDPPKGPVKFDD 23334
Score = 34.3 bits (77), Expect = 1.4
Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 5/67 (7%)
Query: 39 PKPEVTWYKNGQAIDGSGIISNYEFFENQYIHV-LHLSCCTKNDAAVYQISAKNSFGMIC 97
P P V+W+K+G+ + S ++ +N +I L + + DA +Y I+ +N G
Sbjct: 14414 PVPTVSWHKDGKEVKASDRLT----MKNDHISAHLEVPKSVRADAGIYTITLENKLGSAT 14469
Query: 98 CSASVEV 104
S +V+V
Sbjct: 14470 ASINVKV 14476
Score = 34.3 bits (77), Expect = 1.4
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 6/122 (4%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
+ G+P+P++TW K G+ + + ++ L + + D Y ISAKNS G
Sbjct: 17932 VKGRPEPDITWTKEGKVLVRE---KRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSG 17988
Query: 95 MICCSASVEV---ECSSENPQLSPNLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEE 151
SA V V +N +++ +++ W++ E N I E P ++
Sbjct: 17989 HAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGW 18048
Query: 152 SI 153
SI
Sbjct: 18049 SI 18050
Score = 34.3 bits (77), Expect = 1.4
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 16/152 (10%)
Query: 1729 KKILSRVAALRLKLEEKENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVL 1788
+++ S++ R L E+ SA +K E SL EEK +K K A +L
Sbjct: 32512 REVKSQMTETRESLSSYEH--SASAEMKSAALEEKSL---EEKSTTRK--IKTTLAARIL 32564
Query: 1789 LKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQR----SAGDNSTVSFA 1844
K ++ S + SC + T+ W + + ++ R + ST +
Sbjct: 32565 TKPRSMTVYEGESA--RFSCD-TDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEIS 32621
Query: 1845 IVQASPKDQGLYYCCIKNSYGKVTAEFNLTAE 1876
VQAS D+G Y ++NS GK AEF LT +
Sbjct: 32622 SVQAS--DEGNYSVVVENSEGKQEAEFTLTIQ 32651
Score = 33.5 bits (75), Expect = 2.3
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Query: 9 RPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY 68
+ P F+ + + KS A + ++G P +TW K+ Q +D + Y F +
Sbjct: 5045 KEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNV--YISFVDS- 5101
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
+ L + + Y AKN G+ C A + V+
Sbjct: 5102 VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138
Score = 33.5 bits (75), Expect = 2.3
Identities = 25/94 (26%), Positives = 33/94 (35%), Gaps = 3/94 (3%)
Query: 9 RPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY 68
+ P FL L V +L +G VTW K+G I S +
Sbjct: 5983 KEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTS---EKCNIVTTEK 6039
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFGMICCSASV 102
+L + TK DA Y +N G C A V
Sbjct: 6040 TCILEILNSTKRDAGQYSCEIENEAGRDVCGALV 6073
Score = 33.5 bits (75), Expect = 2.3
Identities = 23/109 (21%), Positives = 42/109 (38%), Gaps = 3/109 (2%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P F++ L + L+C ++G P+ V+WYK + + Y + +
Sbjct: 6078 PPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPT---PEYRTYFTNNVA 6134
Query: 71 VLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLED 119
L + ND+ Y A+NS G ++ P + L+D
Sbjct: 6135 TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKD 6183
Score = 33.1 bits (74), Expect = 3.0
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 7/77 (9%)
Query: 37 GQPKPEVTWYKN-GQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGM 95
G+P PE+TW + G+ D I + + L + C +NDA Y + +NS G
Sbjct: 24050 GRPTPEITWSREEGEFTDKVQIEKGVNYTQ------LSIDNCDRNDAGKYILKLENSSGS 24103
Query: 96 ICCSASVEVECSSENPQ 112
+V+V + PQ
Sbjct: 24104 KSAFVTVKVLDTPGPPQ 24120
Score = 33.1 bits (74), Expect = 3.0
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 9/99 (9%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLR--CIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
PP + + K+ VL+ I+G+P P ++W K+G I+ + E
Sbjct: 25786 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEER---ARTEIISTD 25842
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVEC 106
+L + C + D Y ++ KN G + SV V C
Sbjct: 25843 NHTLLTVKDCIRRDTGQYVLTLKNVAG----TRSVAVNC 25877
Score = 32.7 bits (73), Expect = 4.0
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A C I P W+K G+ I S S ++YI L + D Y
Sbjct: 3473 AKFTCEIQSAPNVRFQWFKAGREIYESDKCS---IRSSKYISSLEILRTQVVDCGEYTCK 3529
Query: 89 AKNSFGMICCSASVEV 104
A N +G + C+A++ V
Sbjct: 3530 ASNEYGSVSCTATLTV 3545
Score = 32.7 bits (73), Expect = 4.0
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Query: 1818 TICWTKDSKSI-AQVQRSAG-DNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNL 1873
TI W KD+K + + RS D+++ S + A D G Y C + N G T++ L
Sbjct: 4798 TIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATL 4855
Score = 32.7 bits (73), Expect = 4.0
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
I G+P P+ +W K G+ I S I + +L + T+ DA Y I+A N FG
Sbjct: 20403 ILGKPLPKSSWSKAGKDIRPSDIT---QITSTPTSSMLTIKYATRKDAGEYTITATNPFG 20459
Score = 32.3 bits (72), Expect = 5.2
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 13/106 (12%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFE-----NQY 68
F+ L + + E S ++ +G P P++ W KN S II +++ + +
Sbjct: 1558 FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKN------SDIIVPHKYPKIRIEGTKG 1611
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFG--MICCSASVEVECSSENPQ 112
L + D+A Y +A N G C +VEVE + P+
Sbjct: 1612 EAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPE 1657
Score = 32.3 bits (72), Expect = 5.2
Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query: 33 CIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNS 92
C I+G PK V+WY +G I I + + +S ++ Y A+N
Sbjct: 4883 CQITGTPKIRVSWYLDGNEITA---IQKHGISFIDGLATFQISGARVENSGTYVCEARND 4939
Query: 93 FGMICCSASVEVE 105
G CS ++V+
Sbjct: 4940 AGTASCSIELKVK 4952
Score = 32.3 bits (72), Expect = 5.2
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 1786 PVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQR--SAGDNSTVSF 1843
P +KK++A + +++L C+ + E + W ++ + + + + NS
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIK-VSWFRNDSELHESWKYNMSFINSVALL 6422
Query: 1844 AIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAE 1876
I +AS +D G Y C N G + LT +
Sbjct: 6423 TINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455
Score = 32.3 bits (72), Expect = 5.2
Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 7/82 (8%)
Query: 15 LSTLLSQKVPEKSDAVLRCI--ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVL 72
L + ++ + V+R I +SG+P P VTW N + + I + I
Sbjct: 16526 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVI--- 16582
Query: 73 HLSCCTKNDAAVYQISAKNSFG 94
C ++ VY + AKN G
Sbjct: 16583 --KNCQRSHQGVYSLLAKNEAG 16602
Score = 32.3 bits (72), Expect = 5.2
Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 10 PPLCFLSTLLSQKVPEKS--DAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
PP LS + + K+ + L + G+P P V+W K+G + + + +
Sbjct: 19292 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPA---EGIKMAMQR 19348
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+ L L + D+ Y I+A+NS G + ++V
Sbjct: 19349 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 19385
Score = 32.0 bits (71), Expect = 6.8
Identities = 27/116 (23%), Positives = 48/116 (41%), Gaps = 5/116 (4%)
Query: 1763 TSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWT 1822
TS S + E + P + P ++ +Q + E + C+ + D + W
Sbjct: 3322 TSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQP-ARFQCRVSGT--DLKVSWY 3378
Query: 1823 KDSKSI--AQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAE 1876
K I ++ R T I +A P+D+G Y N+ G+V++ NL+ E
Sbjct: 3379 SKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3434
Score = 32.0 bits (71), Expect = 6.8
Identities = 23/90 (25%), Positives = 37/90 (41%), Gaps = 6/90 (6%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A C ++G +TW K+ + I G + ++ +L + K D+ Y
Sbjct: 6288 ADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVG---KGDSGQYTCQ 6344
Query: 89 AKNSFGMICCSASVEVECSSENPQLSPNLE 118
A N G CSA + V+ E P+ LE
Sbjct: 6345 ATNDVGKDMCSAQLSVK---EPPKFVKKLE 6371
Score = 32.0 bits (71), Expect = 6.8
Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLRCIIS--GQPKPEVTWYKNGQAIDGSGIISNYEFFE-N 66
PP L L + V ++ A LR ++ G+P+PEV W K GI+++ E
Sbjct: 25104 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK------AEGILTDRAQIEVT 25157
Query: 67 QYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENP 111
+L + T+ D+ Y ++ +N+ G +V V S P
Sbjct: 25158 SSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAP 25202
Score = 31.6 bits (70), Expect = 8.9
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Query: 1783 GRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQR--SAGDNST 1840
G AP + K+++ ++ + +LSCQ I W + K + Q ++ + D T
Sbjct: 30530 GEAPGIRKEMK-DVTTKLGEAAQLSCQIVG-RPLPDIKWYRFGKELIQSRKYKMSSDGRT 30587
Query: 1841 VSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQ 1880
+ ++ +D+G+Y C N G+V L + Q
Sbjct: 30588 HTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ 30627
Score = 31.6 bits (70), Expect = 8.9
Identities = 34/139 (24%), Positives = 56/139 (40%), Gaps = 15/139 (10%)
Query: 1746 ENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVK 1805
E ++K++A LE S+ H E K E R +K +M +
Sbjct: 33006 EEVKKSAA-----TSLEKSIVHEEIT---KTSQASEEVRTHAEIKAFSTQMSINEGQRLV 33057
Query: 1806 LSCQFAEIHEDSTICWTKDSKSIAQVQ--RSAGDNSTVSFAIVQASPKDQGLYYCCIKNS 1863
L A I + + W + + + R S + I QAS +D+G+ C K
Sbjct: 33058 LK---ANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTK 33114
Query: 1864 YGKVTAEFNLTAEVLKQLS 1882
G V +++LT + K+LS
Sbjct: 33115 EGIVKCQYDLT--LSKELS 33131
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 63.5 bits (153), Expect = 2e-09
Identities = 35/92 (38%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F L + V +S+A L C ++G PKP V WY+ G+ I G+ + F+ Y H L
Sbjct: 24625 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGY-HQLI 24683
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
++ T +DA VYQ+ A N G + +AS+EVE
Sbjct: 24684 IASVTDDDATVYQVRATNQGGSVSGTASLEVE 24715
Score = 62.0 bits (149), Expect = 6e-09
Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F+S SQ + E + + C ISG+P PE+ W+KN I I SN ++ ++ L
Sbjct: 26831 FISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI---SISSNVSISRSRNVYSLE 26887
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETGTHE 133
+ + +D+ Y I AKN G +AS+ V E P L D + +
Sbjct: 26888 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQS 26947
Query: 134 EERANQIDEKEHPYKEEESISPGTPRSADSSPSKSNHSLSLQSLGNLD---ISVSSS 187
+ + K+E S S + SA S S+S QS+ ++ + +SSS
Sbjct: 26948 VQMSAS--------KQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSS 26996
Score = 49.7 bits (117), Expect = 3e-05
Identities = 24/70 (34%), Positives = 38/70 (54%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
I+ P+P VTWYK+GQ I Y F ++ ++ L ++ T +D A Y + A+N +G
Sbjct: 25408 ITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG 25467
Query: 95 MICCSASVEV 104
C A + V
Sbjct: 25468 EDSCKAKLTV 25477
Score = 47.8 bits (112), Expect = 1e-04
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 8/111 (7%)
Query: 22 KVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY--IHVLHLSCCTK 79
+V E A RC ++G P+P+V WY NGQ +I + F +Y IH L + C
Sbjct: 1805 RVLEGETARFRCRVTGYPQPKVNWYLNGQ------LIRKSKRFRVRYDGIHYLDIVDCKS 1858
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETG 130
D +++A+N G+I +E++ + + + R HE G
Sbjct: 1859 YDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPG 1909
Score = 47.8 bits (112), Expect = 1e-04
Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query: 34 IISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSF 93
+ISG+P+P+++WYK Q + +F + + L L DAAVY AKN +
Sbjct: 3215 VISGRPQPKISWYKEEQLLSTG---FKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDY 3271
Query: 94 GMICCSASVEVE 105
G+ SAS+ VE
Sbjct: 3272 GVATTSASLSVE 3283
Score = 44.7 bits (104), Expect = 0.001
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 1762 ETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICW 1821
+T+ S K +PK P + PV++ +Q S +V A T W
Sbjct: 26525 KTTESTVTRKTEPKAP--EPISSKPVIVTGLQDTTVS--SDSVAKFAVKATGEPRPTAIW 26580
Query: 1822 TKDSKSIAQ--VQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLK 1879
TKD K+I Q + + D I + D GLY C +KNS G V++ LT + +K
Sbjct: 26581 TKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 26640
Query: 1880 QLSSRQ 1885
+++
Sbjct: 26641 DTEAQK 26646
Score = 43.9 bits (102), Expect = 0.002
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F L S V E S A ISG P PEV+W+++GQ I S + F + L
Sbjct: 8 FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK-LT 66
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLE 118
+ TK ++ Y + A N G +A + V+ + P L+
Sbjct: 67 IPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ 111
Score = 42.7 bits (99), Expect = 0.004
Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 4/105 (3%)
Query: 5 EGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
E P PP +S L + V E L C ISG P P VTWY+ I+ S +++
Sbjct: 891 EIPVTPPT-LVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESS---IDFQIT 946
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
I L + D+ + SA N G + S + V+ S E
Sbjct: 947 FQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 991
Score = 42.7 bits (99), Expect = 0.004
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 4/84 (4%)
Query: 8 QRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
+ PP+ F L Q V E + AVL C +S + +V W+KNG I S YE +
Sbjct: 5976 KEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKS---KKYEIVADG 6031
Query: 68 YIHVLHLSCCTKNDAAVYQISAKN 91
+ L + CT D Y AK+
Sbjct: 6032 RVRKLVIHDCTPEDIKTYTCDAKD 6055
Score = 42.4 bits (98), Expect = 0.005
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 2/109 (1%)
Query: 2 KDSEGPQRPPL-CFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISN 60
++ GP P F++ + QK+ E V C + G PKP V W K+G + +G
Sbjct: 1025 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT-TGYRYK 1083
Query: 61 YEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
+ + L +S +DA Y I +N G SAS+ E E
Sbjct: 1084 VSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132
Score = 42.4 bits (98), Expect = 0.005
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
SQ V + SDA R + G+P PE WYKNG I+ S I Y ++ + L + T
Sbjct: 2040 SQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI--YWYWPEDNVCELVIRDVTA 2097
Query: 80 NDAAVYQISAKNSFG 94
D+A + A N G
Sbjct: 2098 EDSASIMVKAINIAG 2112
Score = 42.0 bits (97), Expect = 0.007
Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 4/107 (3%)
Query: 3 DSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYE 62
DSE P+ F+ + + + A L + G PKP++ W+ NG + S ++Y+
Sbjct: 3641 DSEKEGTGPI-FIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPS---ADYK 3696
Query: 63 FFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
F + H L + D Y A N +G CSA +++ E
Sbjct: 3697 FVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGE 3743
Score = 42.0 bits (97), Expect = 0.007
Identities = 47/195 (24%), Positives = 79/195 (40%), Gaps = 31/195 (15%)
Query: 1699 PGTLTAVTGSEEVK----RKPEAPGSGHLAEGVKKKILSRVAALRLKLEEKENIRKNSAF 1754
PG +T V + KPE+ G KI V ++ K EK +
Sbjct: 18994 PGRVTLVDVTRNTATIKWEKPESDGGS--------KITGYVVEMQTKGSEKWS---TCTQ 19042
Query: 1755 LKKMPKLETSLSHTEE------KQDPKKPSCKREGRAPVLLKKIQAEM---FPEHSGNVK 1805
+K + + L+ EE + K S R+ PV+ + I+ + P H+ NVK
Sbjct: 19043 VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVK 19102
Query: 1806 LSCQFA-----EIHEDSTICWTKDSKSIAQVQRS--AGDNSTVSFAIVQASPKDQGLYYC 1858
Q + +T+ W KD +++ + R + + S +I +AS +D G Y
Sbjct: 19103 AREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYEL 19162
Query: 1859 CIKNSYGKVTAEFNL 1873
C+ NS G +T +
Sbjct: 19163 CVSNSAGSITVPITI 19177
Score = 40.0 bits (92), Expect = 0.025
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S + + ++ E C +SG P P++ WYK+G+ I G +F ++ L
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGRAS-LR 1304
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE--NPQLSPNLE 118
+ D +Y A N G CS + VE ++ P P LE
Sbjct: 1305 IPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLE 1351
Score = 40.0 bits (92), Expect = 0.025
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF-ENQYIHVL 72
F L + + E +SG P P + W K+GQ + + N E E + L
Sbjct: 25492 FKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLS---LGPNIEIIHEGLDYYAL 25548
Query: 73 HLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
H+ D Y+++A N+ G C A ++VE
Sbjct: 25549 HIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25581
Score = 39.7 bits (91), Expect = 0.033
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P F+ L Q V E DAV C +S + K V WY+NG+ I Y+F ++ IH
Sbjct: 6517 PTEFVEHLEDQTVTEFDDAVFSCQLSRE-KANVKWYRNGREIKEG---KKYKFEKDGSIH 6572
Query: 71 VLHLSCCTKNDAAVY 85
L + C +D Y
Sbjct: 6573 RLIIKDCRLDDECEY 6587
Score = 39.7 bits (91), Expect = 0.033
Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 5/87 (5%)
Query: 21 QKVPEKSDAVLRCII--SGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCT 78
Q SD+V + + +G+P+P W K+G+AI G Y+ E++ L +
Sbjct: 26554 QDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGG---KYKLSEDKGGFFLEIHKTD 26610
Query: 79 KNDAAVYQISAKNSFGMICCSASVEVE 105
+D+ +Y + KNS G + S + ++
Sbjct: 26611 TSDSGLYTCTVKNSAGSVSSSCKLTIK 26637
Score = 38.5 bits (88), Expect = 0.072
Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAK 90
++ ++ G+P P VTW+K+G I+ N E + L + T++ VY + AK
Sbjct: 21673 IKALVQGRPVPRVTWFKDGVEIEKR---MNMEITDVLGSTSLFVRDATRDHRGVYTVEAK 21729
Query: 91 NSFGMICCSASVEVE 105
N+ G V+V+
Sbjct: 21730 NASGSAKAEIKVKVQ 21744
Score = 37.4 bits (85), Expect = 0.16
Identities = 40/160 (25%), Positives = 64/160 (40%), Gaps = 24/160 (15%)
Query: 1764 SLSHTEEKQDPKKPSCKRE-GRAPVLLKKIQAEMFPEHSGNVKLSC----QFAEIHEDST 1818
SLS E + K K G AP + +Q +V + C QF + +D +
Sbjct: 3466 SLSQIAESTELSKECAKESTGEAPKIFLHLQ---------DVTVKCGDTAQFLCVLKDDS 3516
Query: 1819 ---ICWTKDSKSIAQVQR-SAGDNSTVSF-AIVQASPKDQGLYYCCIKNSYGKVTAEFNL 1873
+ WT + I + +R N + F I DQGLY C + N G+ T L
Sbjct: 3517 FIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVL 3576
Query: 1874 TAE-----VLKQLSSRQDTKGCEEIEFSQLIFKEDFLHDS 1908
+ E +L + ++ +E S L +E+ LH +
Sbjct: 3577 SVEGAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSA 3616
Score = 37.4 bits (85), Expect = 0.16
Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A L C I G+P P++ WY+ G+ + S Y+ + H L + + D VY
Sbjct: 24245 AQLSCQIVGRPLPDIKWYRFGKELIQS---RKYKMSSDGRTHTLTVMTEEQEDEGVYTCI 24301
Query: 89 AKNSFGMICCSASVEVECSSENPQLSP 115
A N G + S+ + ++ + PQ P
Sbjct: 24302 ATNEVGEVETSSKLLLQAT---PQFHP 24325
Score = 37.4 bits (85), Expect = 0.16
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S V E A C G+P P VTW + GQ + S + ++ +Y +S
Sbjct: 26264 SMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTS---ARHQVTTTKYKSTFEISSVQA 26320
Query: 80 NDAAVYQISAKNSFG 94
+D Y + +NS G
Sbjct: 26321 SDEGNYSVVVENSEG 26335
Score = 37.0 bits (84), Expect = 0.21
Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 27 SDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQ 86
SD VL + G+P+P++ W K + +D +S ++ + V+ C ++D+ Y
Sbjct: 22758 SDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS-LQYTGKRATAVIKF--CDRSDSGKYT 22814
Query: 87 ISAKNSFGMICCSASVEV 104
++ KN+ G S V+V
Sbjct: 22815 LTVKNASGTKAVSVMVKV 22832
Score = 37.0 bits (84), Expect = 0.21
Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 36 SGQPKPEVTWYKNGQAIDGSGIISNYE-FFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
SG+P P +TW K ID +G +Y+ + ++ + + DA Y + AKN FG
Sbjct: 24747 SGKPDPVITWQKGQDLIDNNG---HYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 24803
Query: 95 MICCSASVEVECSSENP---QLSPNLEDDRDRGWKHETGTHEEERANQIDEK 143
+ + ++V + P ++S D + W + N I EK
Sbjct: 24804 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEK 24855
Score = 36.6 bits (83), Expect = 0.28
Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1786 PVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSA--GDNSTVSF 1843
P +L+++Q SG C I W K+ + ++ + D +
Sbjct: 3193 PQVLQELQPVTV--QSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 1844 AIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQD 1886
+++A P+D +Y C KN YG T +L+ EV + +S Q+
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3293
Score = 36.6 bits (83), Expect = 0.28
Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
+ G+PKP VTW K Q + + + N+E I L+++ C ++D+ Y ++A+N G
Sbjct: 14784 VLGRPKPTVTWKKGDQILKQTQRV-NFETTATSTI--LNINECVRSDSGPYPLTARNIVG 14840
Query: 95 MICCSASVEV 104
+ +++V
Sbjct: 14841 EVGDVITIQV 14850
Score = 36.2 bits (82), Expect = 0.36
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 7/88 (7%)
Query: 19 LSQKVPEKSDAVLRCIIS--GQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSC 76
L + V ++ A LR ++S G+P P +TW K G + II E + +L +
Sbjct: 23147 LKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYS-----LLIVDK 23201
Query: 77 CTKNDAAVYQISAKNSFGMICCSASVEV 104
+ DA Y I A+N G + V+V
Sbjct: 23202 VNRYDAGKYTIEAENQSGKKSATVLVKV 23229
Score = 35.8 bits (81), Expect = 0.47
Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 6/144 (4%)
Query: 1763 TSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWT 1822
TS S + E + P + P ++ +Q + E + C+ + D + W
Sbjct: 3276 TSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQP-ARFQCRVSGT--DLKVSWY 3332
Query: 1823 KDSKSI--AQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQ 1880
K I ++ R T I +A P+D+G Y N+ G+V++ NL+ EV +
Sbjct: 3333 SKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEV-QA 3391
Query: 1881 LSSRQDTKGCEEIEFSQLIFKEDF 1904
L + K E SQ + F
Sbjct: 3392 LDRQSSGKDVRESAKSQAVADSSF 3415
Score = 35.8 bits (81), Expect = 0.47
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 28 DAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQI 87
D + + G+P+P ++W K+G+ + + + N E E VLH+ K+D Y +
Sbjct: 18023 DLKIEIPVIGRPRPNISWVKDGEPLKQTTRV-NVE--ETATSTVLHIKEGNKDDFGKYTV 18079
Query: 88 SAKNSFGMICCSASVEV 104
+A NS G + SV V
Sbjct: 18080 TATNSAGTATENLSVIV 18096
Score = 35.4 bits (80), Expect = 0.61
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 10/95 (10%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYI 69
P LC+L+ E S+ L+ I G+P P V+W K + +S N +
Sbjct: 13683 PDLCYLAK-------ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTL 13735
Query: 70 HVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
V C K+DA Y I+ KN G + S++V
Sbjct: 13736 IVYD---CQKSDAGKYTITLKNVAGTKEGTISIKV 13767
Score = 35.4 bits (80), Expect = 0.61
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFEN--QYIHVLHLSCCTKNDAAVYQIS 88
L + G+P P +TW+ + + S I+ EN Y H++ + K A Y++
Sbjct: 24343 LHVMYIGRPVPAMTWFHGQKLLQNSENIT----IENTEHYTHLVMKNVQRKTHAGKYKVQ 24398
Query: 89 AKNSFGMICCSASVEVECSSENP 111
N FG + VE++ + P
Sbjct: 24399 LSNVFGTVDAILDVEIQDKPDKP 24421
Score = 35.4 bits (80), Expect = 0.61
Identities = 20/82 (24%), Positives = 34/82 (41%), Gaps = 1/82 (1%)
Query: 23 VPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDA 82
+ E + C +G+P PEVTW G+ I S + + L + K D
Sbjct: 27035 IDEGKVLTVACAFTGEPTPEVTWSCGGRKIH-SQEQGRFHIENTDDLTTLIIMDVQKQDG 27093
Query: 83 AVYQISAKNSFGMICCSASVEV 104
+Y +S N FG + ++ +
Sbjct: 27094 GLYTLSLGNEFGSDSATVNIHI 27115
Score = 35.0 bits (79), Expect = 0.80
Identities = 33/139 (23%), Positives = 50/139 (35%), Gaps = 6/139 (4%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A C I P W+K G+ I S S ++YI L + D Y
Sbjct: 4546 AKFTCEIQSAPNVRFQWFKAGREIYESDKCS---IRSSKYISSLEILRTQVVDCGEYTCK 4602
Query: 89 AKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETGTHE--EERANQIDEKEHP 146
A N +G + C+A++ V ++ L +R K E +R + + K P
Sbjct: 4603 ASNEYGSVSCTATLTVTVPGGEKKVR-KLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEP 4661
Query: 147 YKEEESISPGTPRSADSSP 165
K E+ P P P
Sbjct: 4662 KKLEKVKKPAVPEPPPPKP 4680
Score = 35.0 bits (79), Expect = 0.80
Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 17/159 (10%)
Query: 7 PQRPPLCFLSTLLSQKVPEKSDAVLR--CIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
PQ PP L + + + LR +++G+P P W K +D ++ +
Sbjct: 8793 PQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 8852
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV-ECSSENPQLSP-------- 115
+++ I + + D Y I+A NS G +A VEV + L P
Sbjct: 8853 KSELI----IKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8908
Query: 116 --NLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEES 152
N D D G TG E + ++ P + E S
Sbjct: 8909 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERS 8947
Score = 34.7 bits (78), Expect = 1.0
Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 4/101 (3%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S V D + ISG+PKP +TW K+G + + I+ + + + L + K
Sbjct: 16933 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD---LTTLSIKETHK 16989
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDD 120
+D Y I+ N G S + V +P P DD
Sbjct: 16990 DDGGQYGITVANVVGQKTASIEI-VTLDKPDPPKGPVKFDD 17029
Score = 34.3 bits (77), Expect = 1.4
Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 5/67 (7%)
Query: 39 PKPEVTWYKNGQAIDGSGIISNYEFFENQYIHV-LHLSCCTKNDAAVYQISAKNSFGMIC 97
P P V+W+K+G+ + S ++ +N +I L + + DA +Y I+ +N G
Sbjct: 8109 PVPTVSWHKDGKEVKASDRLT----MKNDHISAHLEVPKSVRADAGIYTITLENKLGSAT 8164
Query: 98 CSASVEV 104
S +V+V
Sbjct: 8165 ASINVKV 8171
Score = 34.3 bits (77), Expect = 1.4
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 6/122 (4%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
+ G+P+P++TW K G+ + + ++ L + + D Y ISAKNS G
Sbjct: 11627 VKGRPEPDITWTKEGKVLVRE---KRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSG 11683
Query: 95 MICCSASVEV---ECSSENPQLSPNLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEE 151
SA V V +N +++ +++ W++ E N I E P ++
Sbjct: 11684 HAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGW 11743
Query: 152 SI 153
SI
Sbjct: 11744 SI 11745
Score = 34.3 bits (77), Expect = 1.4
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 16/152 (10%)
Query: 1729 KKILSRVAALRLKLEEKENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVL 1788
+++ S++ R L E+ SA +K E SL EEK +K K A +L
Sbjct: 26207 REVKSQMTETRESLSSYEH--SASAEMKSAALEEKSL---EEKSTTRK--IKTTLAARIL 26259
Query: 1789 LKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQR----SAGDNSTVSFA 1844
K ++ S + SC + T+ W + + ++ R + ST +
Sbjct: 26260 TKPRSMTVYEGESA--RFSCD-TDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEIS 26316
Query: 1845 IVQASPKDQGLYYCCIKNSYGKVTAEFNLTAE 1876
VQAS D+G Y ++NS GK AEF LT +
Sbjct: 26317 SVQAS--DEGNYSVVVENSEGKQEAEFTLTIQ 26346
Score = 33.1 bits (74), Expect = 3.0
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 7/77 (9%)
Query: 37 GQPKPEVTWYKN-GQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGM 95
G+P PE+TW + G+ D I + + L + C +NDA Y + +NS G
Sbjct: 17745 GRPTPEITWSREEGEFTDKVQIEKGVNYTQ------LSIDNCDRNDAGKYILKLENSSGS 17798
Query: 96 ICCSASVEVECSSENPQ 112
+V+V + PQ
Sbjct: 17799 KSAFVTVKVLDTPGPPQ 17815
Score = 33.1 bits (74), Expect = 3.0
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 9/99 (9%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLR--CIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
PP + + K+ VL+ I+G+P P ++W K+G I+ + E
Sbjct: 19481 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEER---ARTEIISTD 19537
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVEC 106
+L + C + D Y ++ KN G + SV V C
Sbjct: 19538 NHTLLTVKDCIRRDTGQYVLTLKNVAG----TRSVAVNC 19572
Score = 32.7 bits (73), Expect = 4.0
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
I G+P P+ +W K G+ I S I + +L + T+ DA Y I+A N FG
Sbjct: 14098 ILGKPLPKSSWSKAGKDIRPSDIT---QITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14154
Score = 32.3 bits (72), Expect = 5.2
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 13/106 (12%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFE-----NQY 68
F+ L + + E S ++ +G P P++ W KN S II +++ + +
Sbjct: 1512 FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKN------SDIIVPHKYPKIRIEGTKG 1565
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFG--MICCSASVEVECSSENPQ 112
L + D+A Y +A N G C +VEVE + P+
Sbjct: 1566 EAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPE 1611
Score = 32.3 bits (72), Expect = 5.2
Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 7/82 (8%)
Query: 15 LSTLLSQKVPEKSDAVLRCI--ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVL 72
L + ++ + V+R I +SG+P P VTW N + + I + I
Sbjct: 10221 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVI--- 10277
Query: 73 HLSCCTKNDAAVYQISAKNSFG 94
C ++ VY + AKN G
Sbjct: 10278 --KNCQRSHQGVYSLLAKNEAG 10297
Score = 32.3 bits (72), Expect = 5.2
Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 10 PPLCFLSTLLSQKVPEKS--DAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
PP LS + + K+ + L + G+P P V+W K+G + + + +
Sbjct: 12987 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPA---EGIKMAMQR 13043
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+ L L + D+ Y I+A+NS G + ++V
Sbjct: 13044 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 13080
Score = 32.0 bits (71), Expect = 6.8
Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLRCIIS--GQPKPEVTWYKNGQAIDGSGIISNYEFFE-N 66
PP L L + V ++ A LR ++ G+P+PEV W K GI+++ E
Sbjct: 18799 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK------AEGILTDRAQIEVT 18852
Query: 67 QYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENP 111
+L + T+ D+ Y ++ +N+ G +V V S P
Sbjct: 18853 SSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAP 18897
Score = 31.6 bits (70), Expect = 8.9
Identities = 23/103 (22%), Positives = 41/103 (39%), Gaps = 20/103 (19%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P FL L + + A+ + G+P P VTW+K N + + Y
Sbjct: 3766 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFK-----------ENKQLCTSVYYT 3814
Query: 71 VLH---------LSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
++H ++ + D+ +Y A+N G C+A + V
Sbjct: 3815 IIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 31.6 bits (70), Expect = 8.9
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Query: 1783 GRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQR--SAGDNST 1840
G AP + K+++ ++ + +LSCQ I W + K + Q ++ + D T
Sbjct: 24225 GEAPGIRKEMK-DVTTKLGEAAQLSCQIVG-RPLPDIKWYRFGKELIQSRKYKMSSDGRT 24282
Query: 1841 VSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQ 1880
+ ++ +D+G+Y C N G+V L + Q
Sbjct: 24283 HTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ 24322
Score = 31.6 bits (70), Expect = 8.9
Identities = 34/139 (24%), Positives = 56/139 (40%), Gaps = 15/139 (10%)
Query: 1746 ENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVK 1805
E ++K++A LE S+ H E K E R +K +M +
Sbjct: 26701 EEVKKSAA-----TSLEKSIVHEEIT---KTSQASEEVRTHAEIKAFSTQMSINEGQRLV 26752
Query: 1806 LSCQFAEIHEDSTICWTKDSKSIAQVQ--RSAGDNSTVSFAIVQASPKDQGLYYCCIKNS 1863
L A I + + W + + + R S + I QAS +D+G+ C K
Sbjct: 26753 LK---ANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTK 26809
Query: 1864 YGKVTAEFNLTAEVLKQLS 1882
G V +++LT + K+LS
Sbjct: 26810 EGIVKCQYDLT--LSKELS 26826
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 63.5 bits (153), Expect = 2e-09
Identities = 35/92 (38%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F L + V +S+A L C ++G PKP V WY+ G+ I G+ + F+ Y H L
Sbjct: 24558 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGY-HQLI 24616
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
++ T +DA VYQ+ A N G + +AS+EVE
Sbjct: 24617 IASVTDDDATVYQVRATNQGGSVSGTASLEVE 24648
Score = 62.0 bits (149), Expect = 6e-09
Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F+S SQ + E + + C ISG+P PE+ W+KN I I SN ++ ++ L
Sbjct: 26764 FISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI---SISSNVSISRSRNVYSLE 26820
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETGTHE 133
+ + +D+ Y I AKN G +AS+ V E P L D + +
Sbjct: 26821 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQS 26880
Query: 134 EERANQIDEKEHPYKEEESISPGTPRSADSSPSKSNHSLSLQSLGNLD---ISVSSS 187
+ + K+E S S + SA S S+S QS+ ++ + +SSS
Sbjct: 26881 VQMSAS--------KQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSS 26929
Score = 49.7 bits (117), Expect = 3e-05
Identities = 24/70 (34%), Positives = 38/70 (54%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
I+ P+P VTWYK+GQ I Y F ++ ++ L ++ T +D A Y + A+N +G
Sbjct: 25341 ITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG 25400
Query: 95 MICCSASVEV 104
C A + V
Sbjct: 25401 EDSCKAKLTV 25410
Score = 47.8 bits (112), Expect = 1e-04
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 8/111 (7%)
Query: 22 KVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY--IHVLHLSCCTK 79
+V E A RC ++G P+P+V WY NGQ +I + F +Y IH L + C
Sbjct: 1805 RVLEGETARFRCRVTGYPQPKVNWYLNGQ------LIRKSKRFRVRYDGIHYLDIVDCKS 1858
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETG 130
D +++A+N G+I +E++ + + + R HE G
Sbjct: 1859 YDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPG 1909
Score = 47.8 bits (112), Expect = 1e-04
Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query: 34 IISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSF 93
+ISG+P+P+++WYK Q + +F + + L L DAAVY AKN +
Sbjct: 3215 VISGRPQPKISWYKEEQLLSTG---FKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDY 3271
Query: 94 GMICCSASVEVE 105
G+ SAS+ VE
Sbjct: 3272 GVATTSASLSVE 3283
Score = 44.7 bits (104), Expect = 0.001
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 1762 ETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICW 1821
+T+ S K +PK P + PV++ +Q S +V A T W
Sbjct: 26458 KTTESTVTRKTEPKAP--EPISSKPVIVTGLQDTTVS--SDSVAKFAVKATGEPRPTAIW 26513
Query: 1822 TKDSKSIAQ--VQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLK 1879
TKD K+I Q + + D I + D GLY C +KNS G V++ LT + +K
Sbjct: 26514 TKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 26573
Query: 1880 QLSSRQ 1885
+++
Sbjct: 26574 DTEAQK 26579
Score = 44.3 bits (103), Expect = 0.001
Identities = 45/181 (24%), Positives = 75/181 (41%), Gaps = 16/181 (8%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F+ L S +V +SG PKPE+ W+ N Q I + + + F E+ + ++
Sbjct: 3421 FIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVV-FHFEESTGMALML 3479
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWK------- 126
+ A Y A NS G C+A++ V + L +E + + K
Sbjct: 3480 IVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFL 3539
Query: 127 --HETGTHEEE-RANQIDEKEHPYKEEESISPGTPRSADSSPSKSNHSLSLQSLGNLDIS 183
E G H E + ++I+E E S SP P DS + + ++ + N DIS
Sbjct: 3540 SAEEEGLHSAELQLSKINET----LELLSESPVYPTKFDSE-KEGTGPIFIKEVSNADIS 3594
Query: 184 V 184
+
Sbjct: 3595 M 3595
Score = 43.9 bits (102), Expect = 0.002
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F L S V E S A ISG P PEV+W+++GQ I S + F + L
Sbjct: 8 FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK-LT 66
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLE 118
+ TK ++ Y + A N G +A + V+ + P L+
Sbjct: 67 IPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ 111
Score = 42.7 bits (99), Expect = 0.004
Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 4/105 (3%)
Query: 5 EGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
E P PP +S L + V E L C ISG P P VTWY+ I+ S +++
Sbjct: 891 EIPVTPPT-LVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESS---IDFQIT 946
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
I L + D+ + SA N G + S + V+ S E
Sbjct: 947 FQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 991
Score = 42.7 bits (99), Expect = 0.004
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 4/84 (4%)
Query: 8 QRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
+ PP+ F L Q V E + AVL C +S + +V W+KNG I S YE +
Sbjct: 5909 KEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKS---KKYEIVADG 5964
Query: 68 YIHVLHLSCCTKNDAAVYQISAKN 91
+ L + CT D Y AK+
Sbjct: 5965 RVRKLVIHDCTPEDIKTYTCDAKD 5988
Score = 42.4 bits (98), Expect = 0.005
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 2/109 (1%)
Query: 2 KDSEGPQRPPL-CFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISN 60
++ GP P F++ + QK+ E V C + G PKP V W K+G + +G
Sbjct: 1025 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT-TGYRYK 1083
Query: 61 YEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
+ + L +S +DA Y I +N G SAS+ E E
Sbjct: 1084 VSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132
Score = 42.4 bits (98), Expect = 0.005
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
SQ V + SDA R + G+P PE WYKNG I+ S I Y ++ + L + T
Sbjct: 2040 SQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI--YWYWPEDNVCELVIRDVTA 2097
Query: 80 NDAAVYQISAKNSFG 94
D+A + A N G
Sbjct: 2098 EDSASIMVKAINIAG 2112
Score = 42.0 bits (97), Expect = 0.007
Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 4/107 (3%)
Query: 3 DSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYE 62
DSE P+ F+ + + + A L + G PKP++ W+ NG + S ++Y+
Sbjct: 3574 DSEKEGTGPI-FIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPS---ADYK 3629
Query: 63 FFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
F + H L + D Y A N +G CSA +++ E
Sbjct: 3630 FVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGE 3676
Score = 42.0 bits (97), Expect = 0.007
Identities = 47/195 (24%), Positives = 79/195 (40%), Gaps = 31/195 (15%)
Query: 1699 PGTLTAVTGSEEVK----RKPEAPGSGHLAEGVKKKILSRVAALRLKLEEKENIRKNSAF 1754
PG +T V + KPE+ G KI V ++ K EK +
Sbjct: 18927 PGRVTLVDVTRNTATIKWEKPESDGGS--------KITGYVVEMQTKGSEKWS---TCTQ 18975
Query: 1755 LKKMPKLETSLSHTEE------KQDPKKPSCKREGRAPVLLKKIQAEM---FPEHSGNVK 1805
+K + + L+ EE + K S R+ PV+ + I+ + P H+ NVK
Sbjct: 18976 VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVK 19035
Query: 1806 LSCQFA-----EIHEDSTICWTKDSKSIAQVQRS--AGDNSTVSFAIVQASPKDQGLYYC 1858
Q + +T+ W KD +++ + R + + S +I +AS +D G Y
Sbjct: 19036 AREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYEL 19095
Query: 1859 CIKNSYGKVTAEFNL 1873
C+ NS G +T +
Sbjct: 19096 CVSNSAGSITVPITI 19110
Score = 40.0 bits (92), Expect = 0.025
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S + + ++ E C +SG P P++ WYK+G+ I G +F ++ L
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGRAS-LR 1304
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE--NPQLSPNLE 118
+ D +Y A N G CS + VE ++ P P LE
Sbjct: 1305 IPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLE 1351
Score = 40.0 bits (92), Expect = 0.025
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF-ENQYIHVL 72
F L + + E +SG P P + W K+GQ + + N E E + L
Sbjct: 25425 FKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLS---LGPNIEIIHEGLDYYAL 25481
Query: 73 HLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
H+ D Y+++A N+ G C A ++VE
Sbjct: 25482 HIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25514
Score = 39.7 bits (91), Expect = 0.033
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P F+ L Q V E DAV C +S + K V WY+NG+ I Y+F ++ IH
Sbjct: 6450 PTEFVEHLEDQTVTEFDDAVFSCQLSRE-KANVKWYRNGREIKEG---KKYKFEKDGSIH 6505
Query: 71 VLHLSCCTKNDAAVY 85
L + C +D Y
Sbjct: 6506 RLIIKDCRLDDECEY 6520
Score = 39.7 bits (91), Expect = 0.033
Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 5/87 (5%)
Query: 21 QKVPEKSDAVLRCII--SGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCT 78
Q SD+V + + +G+P+P W K+G+AI G Y+ E++ L +
Sbjct: 26487 QDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGG---KYKLSEDKGGFFLEIHKTD 26543
Query: 79 KNDAAVYQISAKNSFGMICCSASVEVE 105
+D+ +Y + KNS G + S + ++
Sbjct: 26544 TSDSGLYTCTVKNSAGSVSSSCKLTIK 26570
Score = 38.5 bits (88), Expect = 0.072
Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAK 90
++ ++ G+P P VTW+K+G I+ N E + L + T++ VY + AK
Sbjct: 21606 IKALVQGRPVPRVTWFKDGVEIEKR---MNMEITDVLGSTSLFVRDATRDHRGVYTVEAK 21662
Query: 91 NSFGMICCSASVEVE 105
N+ G V+V+
Sbjct: 21663 NASGSAKAEIKVKVQ 21677
Score = 37.4 bits (85), Expect = 0.16
Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A L C I G+P P++ WY+ G+ + S Y+ + H L + + D VY
Sbjct: 24178 AQLSCQIVGRPLPDIKWYRFGKELIQS---RKYKMSSDGRTHTLTVMTEEQEDEGVYTCI 24234
Query: 89 AKNSFGMICCSASVEVECSSENPQLSP 115
A N G + S+ + ++ + PQ P
Sbjct: 24235 ATNEVGEVETSSKLLLQAT---PQFHP 24258
Score = 37.4 bits (85), Expect = 0.16
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S V E A C G+P P VTW + GQ + S + ++ +Y +S
Sbjct: 26197 SMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTS---ARHQVTTTKYKSTFEISSVQA 26253
Query: 80 NDAAVYQISAKNSFG 94
+D Y + +NS G
Sbjct: 26254 SDEGNYSVVVENSEG 26268
Score = 37.0 bits (84), Expect = 0.21
Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 27 SDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQ 86
SD VL + G+P+P++ W K + +D +S ++ + V+ C ++D+ Y
Sbjct: 22691 SDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS-LQYTGKRATAVIKF--CDRSDSGKYT 22747
Query: 87 ISAKNSFGMICCSASVEV 104
++ KN+ G S V+V
Sbjct: 22748 LTVKNASGTKAVSVMVKV 22765
Score = 37.0 bits (84), Expect = 0.21
Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 36 SGQPKPEVTWYKNGQAIDGSGIISNYE-FFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
SG+P P +TW K ID +G +Y+ + ++ + + DA Y + AKN FG
Sbjct: 24680 SGKPDPVITWQKGQDLIDNNG---HYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 24736
Query: 95 MICCSASVEVECSSENP---QLSPNLEDDRDRGWKHETGTHEEERANQIDEK 143
+ + ++V + P ++S D + W + N I EK
Sbjct: 24737 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEK 24788
Score = 36.6 bits (83), Expect = 0.28
Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1786 PVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSA--GDNSTVSF 1843
P +L+++Q SG C I W K+ + ++ + D +
Sbjct: 3193 PQVLQELQPVTV--QSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 1844 AIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQD 1886
+++A P+D +Y C KN YG T +L+ EV + +S Q+
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3293
Score = 36.6 bits (83), Expect = 0.28
Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
+ G+PKP VTW K Q + + + N+E I L+++ C ++D+ Y ++A+N G
Sbjct: 14717 VLGRPKPTVTWKKGDQILKQTQRV-NFETTATSTI--LNINECVRSDSGPYPLTARNIVG 14773
Query: 95 MICCSASVEV 104
+ +++V
Sbjct: 14774 EVGDVITIQV 14783
Score = 36.2 bits (82), Expect = 0.36
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 7/88 (7%)
Query: 19 LSQKVPEKSDAVLRCIIS--GQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSC 76
L + V ++ A LR ++S G+P P +TW K G + II E + +L +
Sbjct: 23080 LKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYS-----LLIVDK 23134
Query: 77 CTKNDAAVYQISAKNSFGMICCSASVEV 104
+ DA Y I A+N G + V+V
Sbjct: 23135 VNRYDAGKYTIEAENQSGKKSATVLVKV 23162
Score = 35.8 bits (81), Expect = 0.47
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 28 DAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQI 87
D + + G+P+P ++W K+G+ + + + N E E VLH+ K+D Y +
Sbjct: 17956 DLKIEIPVIGRPRPNISWVKDGEPLKQTTRV-NVE--ETATSTVLHIKEGNKDDFGKYTV 18012
Query: 88 SAKNSFGMICCSASVEV 104
+A NS G + SV V
Sbjct: 18013 TATNSAGTATENLSVIV 18029
Score = 35.4 bits (80), Expect = 0.61
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 10/95 (10%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYI 69
P LC+L+ E S+ L+ I G+P P V+W K + +S N +
Sbjct: 13616 PDLCYLAK-------ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTL 13668
Query: 70 HVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
V C K+DA Y I+ KN G + S++V
Sbjct: 13669 IVYD---CQKSDAGKYTITLKNVAGTKEGTISIKV 13700
Score = 35.4 bits (80), Expect = 0.61
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFEN--QYIHVLHLSCCTKNDAAVYQIS 88
L + G+P P +TW+ + + S I+ EN Y H++ + K A Y++
Sbjct: 24276 LHVMYIGRPVPAMTWFHGQKLLQNSENIT----IENTEHYTHLVMKNVQRKTHAGKYKVQ 24331
Query: 89 AKNSFGMICCSASVEVECSSENP 111
N FG + VE++ + P
Sbjct: 24332 LSNVFGTVDAILDVEIQDKPDKP 24354
Score = 35.4 bits (80), Expect = 0.61
Identities = 20/82 (24%), Positives = 34/82 (41%), Gaps = 1/82 (1%)
Query: 23 VPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDA 82
+ E + C +G+P PEVTW G+ I S + + L + K D
Sbjct: 26968 IDEGKVLTVACAFTGEPTPEVTWSCGGRKIH-SQEQGRFHIENTDDLTTLIIMDVQKQDG 27026
Query: 83 AVYQISAKNSFGMICCSASVEV 104
+Y +S N FG + ++ +
Sbjct: 27027 GLYTLSLGNEFGSDSATVNIHI 27048
Score = 35.0 bits (79), Expect = 0.80
Identities = 33/139 (23%), Positives = 50/139 (35%), Gaps = 6/139 (4%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A C I P W+K G+ I S S ++YI L + D Y
Sbjct: 4479 AKFTCEIQSAPNVRFQWFKAGREIYESDKCS---IRSSKYISSLEILRTQVVDCGEYTCK 4535
Query: 89 AKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETGTHE--EERANQIDEKEHP 146
A N +G + C+A++ V ++ L +R K E +R + + K P
Sbjct: 4536 ASNEYGSVSCTATLTVTVPGGEKKVR-KLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEP 4594
Query: 147 YKEEESISPGTPRSADSSP 165
K E+ P P P
Sbjct: 4595 KKLEKVKKPAVPEPPPPKP 4613
Score = 35.0 bits (79), Expect = 0.80
Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 17/159 (10%)
Query: 7 PQRPPLCFLSTLLSQKVPEKSDAVLR--CIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
PQ PP L + + + LR +++G+P P W K +D ++ +
Sbjct: 8726 PQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 8785
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV-ECSSENPQLSP-------- 115
+++ I + + D Y I+A NS G +A VEV + L P
Sbjct: 8786 KSELI----IKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8841
Query: 116 --NLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEES 152
N D D G TG E + ++ P + E S
Sbjct: 8842 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERS 8880
Score = 34.7 bits (78), Expect = 1.0
Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 4/101 (3%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S V D + ISG+PKP +TW K+G + + I+ + + + L + K
Sbjct: 16866 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD---LTTLSIKETHK 16922
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDD 120
+D Y I+ N G S + V +P P DD
Sbjct: 16923 DDGGQYGITVANVVGQKTASIEI-VTLDKPDPPKGPVKFDD 16962
Score = 34.3 bits (77), Expect = 1.4
Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 5/67 (7%)
Query: 39 PKPEVTWYKNGQAIDGSGIISNYEFFENQYIHV-LHLSCCTKNDAAVYQISAKNSFGMIC 97
P P V+W+K+G+ + S ++ +N +I L + + DA +Y I+ +N G
Sbjct: 8042 PVPTVSWHKDGKEVKASDRLT----MKNDHISAHLEVPKSVRADAGIYTITLENKLGSAT 8097
Query: 98 CSASVEV 104
S +V+V
Sbjct: 8098 ASINVKV 8104
Score = 34.3 bits (77), Expect = 1.4
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 6/122 (4%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
+ G+P+P++TW K G+ + + ++ L + + D Y ISAKNS G
Sbjct: 11560 VKGRPEPDITWTKEGKVLVRE---KRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSG 11616
Query: 95 MICCSASVEV---ECSSENPQLSPNLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEE 151
SA V V +N +++ +++ W++ E N I E P ++
Sbjct: 11617 HAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGW 11676
Query: 152 SI 153
SI
Sbjct: 11677 SI 11678
Score = 34.3 bits (77), Expect = 1.4
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 16/152 (10%)
Query: 1729 KKILSRVAALRLKLEEKENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVL 1788
+++ S++ R L E+ SA +K E SL EEK +K K A +L
Sbjct: 26140 REVKSQMTETRESLSSYEH--SASAEMKSAALEEKSL---EEKSTTRK--IKTTLAARIL 26192
Query: 1789 LKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQR----SAGDNSTVSFA 1844
K ++ S + SC + T+ W + + ++ R + ST +
Sbjct: 26193 TKPRSMTVYEGESA--RFSCD-TDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEIS 26249
Query: 1845 IVQASPKDQGLYYCCIKNSYGKVTAEFNLTAE 1876
VQAS D+G Y ++NS GK AEF LT +
Sbjct: 26250 SVQAS--DEGNYSVVVENSEGKQEAEFTLTIQ 26279
Score = 33.1 bits (74), Expect = 3.0
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 7/77 (9%)
Query: 37 GQPKPEVTWYKN-GQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGM 95
G+P PE+TW + G+ D I + + L + C +NDA Y + +NS G
Sbjct: 17678 GRPTPEITWSREEGEFTDKVQIEKGVNYTQ------LSIDNCDRNDAGKYILKLENSSGS 17731
Query: 96 ICCSASVEVECSSENPQ 112
+V+V + PQ
Sbjct: 17732 KSAFVTVKVLDTPGPPQ 17748
Score = 33.1 bits (74), Expect = 3.0
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 9/99 (9%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLR--CIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
PP + + K+ VL+ I+G+P P ++W K+G I+ + E
Sbjct: 19414 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEER---ARTEIISTD 19470
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVEC 106
+L + C + D Y ++ KN G + SV V C
Sbjct: 19471 NHTLLTVKDCIRRDTGQYVLTLKNVAG----TRSVAVNC 19505
Score = 32.7 bits (73), Expect = 4.0
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
I G+P P+ +W K G+ I S I + +L + T+ DA Y I+A N FG
Sbjct: 14031 ILGKPLPKSSWSKAGKDIRPSDIT---QITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14087
Score = 32.3 bits (72), Expect = 5.2
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 13/106 (12%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFE-----NQY 68
F+ L + + E S ++ +G P P++ W KN S II +++ + +
Sbjct: 1512 FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKN------SDIIVPHKYPKIRIEGTKG 1565
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFG--MICCSASVEVECSSENPQ 112
L + D+A Y +A N G C +VEVE + P+
Sbjct: 1566 EAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPE 1611
Score = 32.3 bits (72), Expect = 5.2
Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 7/82 (8%)
Query: 15 LSTLLSQKVPEKSDAVLRCI--ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVL 72
L + ++ + V+R I +SG+P P VTW N + + I + I
Sbjct: 10154 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVI--- 10210
Query: 73 HLSCCTKNDAAVYQISAKNSFG 94
C ++ VY + AKN G
Sbjct: 10211 --KNCQRSHQGVYSLLAKNEAG 10230
Score = 32.3 bits (72), Expect = 5.2
Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 10 PPLCFLSTLLSQKVPEKS--DAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
PP LS + + K+ + L + G+P P V+W K+G + + + +
Sbjct: 12920 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPA---EGIKMAMQR 12976
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+ L L + D+ Y I+A+NS G + ++V
Sbjct: 12977 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 13013
Score = 32.0 bits (71), Expect = 6.8
Identities = 27/116 (23%), Positives = 48/116 (41%), Gaps = 5/116 (4%)
Query: 1763 TSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWT 1822
TS S + E + P + P ++ +Q + E + C+ + D + W
Sbjct: 3276 TSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQP-ARFQCRVSGT--DLKVSWY 3332
Query: 1823 KDSKSI--AQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAE 1876
K I ++ R T I +A P+D+G Y N+ G+V++ NL+ E
Sbjct: 3333 SKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3388
Score = 32.0 bits (71), Expect = 6.8
Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLRCIIS--GQPKPEVTWYKNGQAIDGSGIISNYEFFE-N 66
PP L L + V ++ A LR ++ G+P+PEV W K GI+++ E
Sbjct: 18732 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK------AEGILTDRAQIEVT 18785
Query: 67 QYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENP 111
+L + T+ D+ Y ++ +N+ G +V V S P
Sbjct: 18786 SSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAP 18830
Score = 31.6 bits (70), Expect = 8.9
Identities = 23/103 (22%), Positives = 41/103 (39%), Gaps = 20/103 (19%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P FL L + + A+ + G+P P VTW+K N + + Y
Sbjct: 3699 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFK-----------ENKQLCTSVYYT 3747
Query: 71 VLH---------LSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
++H ++ + D+ +Y A+N G C+A + V
Sbjct: 3748 IIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3790
Score = 31.6 bits (70), Expect = 8.9
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Query: 1783 GRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQR--SAGDNST 1840
G AP + K+++ ++ + +LSCQ I W + K + Q ++ + D T
Sbjct: 24158 GEAPGIRKEMK-DVTTKLGEAAQLSCQIVG-RPLPDIKWYRFGKELIQSRKYKMSSDGRT 24215
Query: 1841 VSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQ 1880
+ ++ +D+G+Y C N G+V L + Q
Sbjct: 24216 HTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ 24255
Score = 31.6 bits (70), Expect = 8.9
Identities = 34/139 (24%), Positives = 56/139 (40%), Gaps = 15/139 (10%)
Query: 1746 ENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVK 1805
E ++K++A LE S+ H E K E R +K +M +
Sbjct: 26634 EEVKKSAA-----TSLEKSIVHEEIT---KTSQASEEVRTHAEIKAFSTQMSINEGQRLV 26685
Query: 1806 LSCQFAEIHEDSTICWTKDSKSIAQVQ--RSAGDNSTVSFAIVQASPKDQGLYYCCIKNS 1863
L A I + + W + + + R S + I QAS +D+G+ C K
Sbjct: 26686 LK---ANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTK 26742
Query: 1864 YGKVTAEFNLTAEVLKQLS 1882
G V +++LT + K+LS
Sbjct: 26743 EGIVKCQYDLT--LSKELS 26759
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 63.5 bits (153), Expect = 2e-09
Identities = 35/92 (38%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F L + V +S+A L C ++G PKP V WY+ G+ I G+ + F+ Y H L
Sbjct: 24433 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGY-HQLI 24491
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
++ T +DA VYQ+ A N G + +AS+EVE
Sbjct: 24492 IASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523
Score = 62.0 bits (149), Expect = 6e-09
Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 14/177 (7%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F+S SQ + E + + C ISG+P PE+ W+KN I I SN ++ ++ L
Sbjct: 26639 FISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI---SISSNVSISRSRNVYSLE 26695
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETGTHE 133
+ + +D+ Y I AKN G +AS+ V E P L D + +
Sbjct: 26696 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQS 26755
Query: 134 EERANQIDEKEHPYKEEESISPGTPRSADSSPSKSNHSLSLQSLGNLD---ISVSSS 187
+ + K+E S S + SA S S+S QS+ ++ + +SSS
Sbjct: 26756 VQMSAS--------KQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSS 26804
Score = 49.7 bits (117), Expect = 3e-05
Identities = 24/70 (34%), Positives = 38/70 (54%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
I+ P+P VTWYK+GQ I Y F ++ ++ L ++ T +D A Y + A+N +G
Sbjct: 25216 ITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYG 25275
Query: 95 MICCSASVEV 104
C A + V
Sbjct: 25276 EDSCKAKLTV 25285
Score = 48.9 bits (115), Expect = 5e-05
Identities = 67/294 (22%), Positives = 116/294 (39%), Gaps = 37/294 (12%)
Query: 34 IISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSF 93
+ISG+P+P+++WYK Q + +F + + L L DAAVY AKN +
Sbjct: 3215 VISGRPQPKISWYKEEQLLSTG---FKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDY 3271
Query: 94 GMICCSASVEVEC------SSENPQLSPNLEDD-RDRGWKHETGTHEEERANQIDEKEHP 146
G+ SAS+ VE E P P + +D + R + D K
Sbjct: 3272 GVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSW 3331
Query: 147 YKEEESISPGTPRSADSSPSKSNHSLSLQSLGNLDISVSSSENPLGVKGTRHTGEAYDPS 206
Y +++ I PS+ + L+I+ + E+ +GT +
Sbjct: 3332 YSKDKKI----------KPSRFFRMTQFEDTYQLEIAEAYPED----EGTYTFVASNAVG 3377
Query: 207 NTEEIANGLLFLNSSHIYEKQDRCCHKTVHSMASKFTDGDLNNDGPHDEGLRSSQ-QNPK 265
AN L S ++E+ ++ + +S F + +EGL S++ Q K
Sbjct: 3378 QVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAE-------EEGLHSAELQLSK 3430
Query: 266 VQKYISFSLPLSEATAHIYPGDSAVANKQPSPQLSSEDSDSDYELCPEITLTYT 319
+ + + LSE+ +YP + P E S++D + TL+ T
Sbjct: 3431 INETLEL---LSESP--VYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVT 3479
Score = 47.8 bits (112), Expect = 1e-04
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 8/111 (7%)
Query: 22 KVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY--IHVLHLSCCTK 79
+V E A RC ++G P+P+V WY NGQ +I + F +Y IH L + C
Sbjct: 1805 RVLEGETARFRCRVTGYPQPKVNWYLNGQ------LIRKSKRFRVRYDGIHYLDIVDCKS 1858
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETG 130
D +++A+N G+I +E++ + + + R HE G
Sbjct: 1859 YDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPG 1909
Score = 44.7 bits (104), Expect = 0.001
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 1762 ETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICW 1821
+T+ S K +PK P + PV++ +Q S +V A T W
Sbjct: 26333 KTTESTVTRKTEPKAP--EPISSKPVIVTGLQDTTVS--SDSVAKFAVKATGEPRPTAIW 26388
Query: 1822 TKDSKSIAQ--VQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLK 1879
TKD K+I Q + + D I + D GLY C +KNS G V++ LT + +K
Sbjct: 26389 TKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 26448
Query: 1880 QLSSRQ 1885
+++
Sbjct: 26449 DTEAQK 26454
Score = 43.9 bits (102), Expect = 0.002
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F L S V E S A ISG P PEV+W+++GQ I S + F + L
Sbjct: 8 FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK-LT 66
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLE 118
+ TK ++ Y + A N G +A + V+ + P L+
Sbjct: 67 IPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ 111
Score = 42.7 bits (99), Expect = 0.004
Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 4/105 (3%)
Query: 5 EGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
E P PP +S L + V E L C ISG P P VTWY+ I+ S +++
Sbjct: 891 EIPVTPPT-LVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESS---IDFQIT 946
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
I L + D+ + SA N G + S + V+ S E
Sbjct: 947 FQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 991
Score = 42.7 bits (99), Expect = 0.004
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 4/84 (4%)
Query: 8 QRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
+ PP+ F L Q V E + AVL C +S + +V W+KNG I S YE +
Sbjct: 5784 KEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKS---KKYEIVADG 5839
Query: 68 YIHVLHLSCCTKNDAAVYQISAKN 91
+ L + CT D Y AK+
Sbjct: 5840 RVRKLVIHDCTPEDIKTYTCDAKD 5863
Score = 42.4 bits (98), Expect = 0.005
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 2/109 (1%)
Query: 2 KDSEGPQRPPL-CFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISN 60
++ GP P F++ + QK+ E V C + G PKP V W K+G + +G
Sbjct: 1025 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT-TGYRYK 1083
Query: 61 YEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
+ + L +S +DA Y I +N G SAS+ E E
Sbjct: 1084 VSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132
Score = 42.4 bits (98), Expect = 0.005
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
SQ V + SDA R + G+P PE WYKNG I+ S I Y ++ + L + T
Sbjct: 2040 SQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI--YWYWPEDNVCELVIRDVTA 2097
Query: 80 NDAAVYQISAKNSFG 94
D+A + A N G
Sbjct: 2098 EDSASIMVKAINIAG 2112
Score = 42.0 bits (97), Expect = 0.007
Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 4/107 (3%)
Query: 3 DSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYE 62
DSE P+ F+ + + + A L + G PKP++ W+ NG + S ++Y+
Sbjct: 3449 DSEKEGTGPI-FIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPS---ADYK 3504
Query: 63 FFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
F + H L + D Y A N +G CSA +++ E
Sbjct: 3505 FVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGE 3551
Score = 42.0 bits (97), Expect = 0.007
Identities = 47/195 (24%), Positives = 79/195 (40%), Gaps = 31/195 (15%)
Query: 1699 PGTLTAVTGSEEVK----RKPEAPGSGHLAEGVKKKILSRVAALRLKLEEKENIRKNSAF 1754
PG +T V + KPE+ G KI V ++ K EK +
Sbjct: 18802 PGRVTLVDVTRNTATIKWEKPESDGGS--------KITGYVVEMQTKGSEKWS---TCTQ 18850
Query: 1755 LKKMPKLETSLSHTEE------KQDPKKPSCKREGRAPVLLKKIQAEM---FPEHSGNVK 1805
+K + + L+ EE + K S R+ PV+ + I+ + P H+ NVK
Sbjct: 18851 VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVK 18910
Query: 1806 LSCQFA-----EIHEDSTICWTKDSKSIAQVQRS--AGDNSTVSFAIVQASPKDQGLYYC 1858
Q + +T+ W KD +++ + R + + S +I +AS +D G Y
Sbjct: 18911 AREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYEL 18970
Query: 1859 CIKNSYGKVTAEFNL 1873
C+ NS G +T +
Sbjct: 18971 CVSNSAGSITVPITI 18985
Score = 40.0 bits (92), Expect = 0.025
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S + + ++ E C +SG P P++ WYK+G+ I G +F ++ L
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGRAS-LR 1304
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE--NPQLSPNLE 118
+ D +Y A N G CS + VE ++ P P LE
Sbjct: 1305 IPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLE 1351
Score = 40.0 bits (92), Expect = 0.025
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF-ENQYIHVL 72
F L + + E +SG P P + W K+GQ + + N E E + L
Sbjct: 25300 FKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLS---LGPNIEIIHEGLDYYAL 25356
Query: 73 HLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
H+ D Y+++A N+ G C A ++VE
Sbjct: 25357 HIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389
Score = 39.7 bits (91), Expect = 0.033
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P F+ L Q V E DAV C +S + K V WY+NG+ I Y+F ++ IH
Sbjct: 6325 PTEFVEHLEDQTVTEFDDAVFSCQLSRE-KANVKWYRNGREIKEG---KKYKFEKDGSIH 6380
Query: 71 VLHLSCCTKNDAAVY 85
L + C +D Y
Sbjct: 6381 RLIIKDCRLDDECEY 6395
Score = 39.7 bits (91), Expect = 0.033
Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 5/87 (5%)
Query: 21 QKVPEKSDAVLRCII--SGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCT 78
Q SD+V + + +G+P+P W K+G+AI G Y+ E++ L +
Sbjct: 26362 QDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGG---KYKLSEDKGGFFLEIHKTD 26418
Query: 79 KNDAAVYQISAKNSFGMICCSASVEVE 105
+D+ +Y + KNS G + S + ++
Sbjct: 26419 TSDSGLYTCTVKNSAGSVSSSCKLTIK 26445
Score = 38.5 bits (88), Expect = 0.072
Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAK 90
++ ++ G+P P VTW+K+G I+ N E + L + T++ VY + AK
Sbjct: 21481 IKALVQGRPVPRVTWFKDGVEIEKR---MNMEITDVLGSTSLFVRDATRDHRGVYTVEAK 21537
Query: 91 NSFGMICCSASVEVE 105
N+ G V+V+
Sbjct: 21538 NASGSAKAEIKVKVQ 21552
Score = 37.4 bits (85), Expect = 0.16
Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A L C I G+P P++ WY+ G+ + S Y+ + H L + + D VY
Sbjct: 24053 AQLSCQIVGRPLPDIKWYRFGKELIQS---RKYKMSSDGRTHTLTVMTEEQEDEGVYTCI 24109
Query: 89 AKNSFGMICCSASVEVECSSENPQLSP 115
A N G + S+ + ++ + PQ P
Sbjct: 24110 ATNEVGEVETSSKLLLQAT---PQFHP 24133
Score = 37.4 bits (85), Expect = 0.16
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S V E A C G+P P VTW + GQ + S + ++ +Y +S
Sbjct: 26072 SMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTS---ARHQVTTTKYKSTFEISSVQA 26128
Query: 80 NDAAVYQISAKNSFG 94
+D Y + +NS G
Sbjct: 26129 SDEGNYSVVVENSEG 26143
Score = 37.0 bits (84), Expect = 0.21
Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 27 SDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQ 86
SD VL + G+P+P++ W K + +D +S ++ + V+ C ++D+ Y
Sbjct: 22566 SDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS-LQYTGKRATAVIKF--CDRSDSGKYT 22622
Query: 87 ISAKNSFGMICCSASVEV 104
++ KN+ G S V+V
Sbjct: 22623 LTVKNASGTKAVSVMVKV 22640
Score = 37.0 bits (84), Expect = 0.21
Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 36 SGQPKPEVTWYKNGQAIDGSGIISNYE-FFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
SG+P P +TW K ID +G +Y+ + ++ + + DA Y + AKN FG
Sbjct: 24555 SGKPDPVITWQKGQDLIDNNG---HYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 24611
Query: 95 MICCSASVEVECSSENP---QLSPNLEDDRDRGWKHETGTHEEERANQIDEK 143
+ + ++V + P ++S D + W + N I EK
Sbjct: 24612 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEK 24663
Score = 36.6 bits (83), Expect = 0.28
Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1786 PVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSA--GDNSTVSF 1843
P +L+++Q SG C I W K+ + ++ + D +
Sbjct: 3193 PQVLQELQPVTV--QSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 1844 AIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQD 1886
+++A P+D +Y C KN YG T +L+ EV + +S Q+
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3293
Score = 36.6 bits (83), Expect = 0.28
Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
+ G+PKP VTW K Q + + + N+E I L+++ C ++D+ Y ++A+N G
Sbjct: 14592 VLGRPKPTVTWKKGDQILKQTQRV-NFETTATSTI--LNINECVRSDSGPYPLTARNIVG 14648
Query: 95 MICCSASVEV 104
+ +++V
Sbjct: 14649 EVGDVITIQV 14658
Score = 36.2 bits (82), Expect = 0.36
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 7/88 (7%)
Query: 19 LSQKVPEKSDAVLRCIIS--GQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSC 76
L + V ++ A LR ++S G+P P +TW K G + II E + +L +
Sbjct: 22955 LKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYS-----LLIVDK 23009
Query: 77 CTKNDAAVYQISAKNSFGMICCSASVEV 104
+ DA Y I A+N G + V+V
Sbjct: 23010 VNRYDAGKYTIEAENQSGKKSATVLVKV 23037
Score = 35.8 bits (81), Expect = 0.47
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 28 DAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQI 87
D + + G+P+P ++W K+G+ + + + N E E VLH+ K+D Y +
Sbjct: 17831 DLKIEIPVIGRPRPNISWVKDGEPLKQTTRV-NVE--ETATSTVLHIKEGNKDDFGKYTV 17887
Query: 88 SAKNSFGMICCSASVEV 104
+A NS G + SV V
Sbjct: 17888 TATNSAGTATENLSVIV 17904
Score = 35.4 bits (80), Expect = 0.61
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 10/95 (10%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYI 69
P LC+L+ E S+ L+ I G+P P V+W K + +S N +
Sbjct: 13491 PDLCYLAK-------ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTL 13543
Query: 70 HVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
V C K+DA Y I+ KN G + S++V
Sbjct: 13544 IVYD---CQKSDAGKYTITLKNVAGTKEGTISIKV 13575
Score = 35.4 bits (80), Expect = 0.61
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFEN--QYIHVLHLSCCTKNDAAVYQIS 88
L + G+P P +TW+ + + S I+ EN Y H++ + K A Y++
Sbjct: 24151 LHVMYIGRPVPAMTWFHGQKLLQNSENIT----IENTEHYTHLVMKNVQRKTHAGKYKVQ 24206
Query: 89 AKNSFGMICCSASVEVECSSENP 111
N FG + VE++ + P
Sbjct: 24207 LSNVFGTVDAILDVEIQDKPDKP 24229
Score = 35.4 bits (80), Expect = 0.61
Identities = 20/82 (24%), Positives = 34/82 (41%), Gaps = 1/82 (1%)
Query: 23 VPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDA 82
+ E + C +G+P PEVTW G+ I S + + L + K D
Sbjct: 26843 IDEGKVLTVACAFTGEPTPEVTWSCGGRKIH-SQEQGRFHIENTDDLTTLIIMDVQKQDG 26901
Query: 83 AVYQISAKNSFGMICCSASVEV 104
+Y +S N FG + ++ +
Sbjct: 26902 GLYTLSLGNEFGSDSATVNIHI 26923
Score = 35.0 bits (79), Expect = 0.80
Identities = 33/139 (23%), Positives = 50/139 (35%), Gaps = 6/139 (4%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A C I P W+K G+ I S S ++YI L + D Y
Sbjct: 4354 AKFTCEIQSAPNVRFQWFKAGREIYESDKCS---IRSSKYISSLEILRTQVVDCGEYTCK 4410
Query: 89 AKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETGTHE--EERANQIDEKEHP 146
A N +G + C+A++ V ++ L +R K E +R + + K P
Sbjct: 4411 ASNEYGSVSCTATLTVTVPGGEKKVR-KLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEP 4469
Query: 147 YKEEESISPGTPRSADSSP 165
K E+ P P P
Sbjct: 4470 KKLEKVKKPAVPEPPPPKP 4488
Score = 35.0 bits (79), Expect = 0.80
Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 17/159 (10%)
Query: 7 PQRPPLCFLSTLLSQKVPEKSDAVLR--CIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
PQ PP L + + + LR +++G+P P W K +D ++ +
Sbjct: 8601 PQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 8660
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV-ECSSENPQLSP-------- 115
+++ I + + D Y I+A NS G +A VEV + L P
Sbjct: 8661 KSELI----IKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8716
Query: 116 --NLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEES 152
N D D G TG E + ++ P + E S
Sbjct: 8717 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERS 8755
Score = 34.7 bits (78), Expect = 1.0
Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 8/145 (5%)
Query: 1763 TSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWT 1822
TS S + E + P + P ++ +Q + E + C+ + D + W
Sbjct: 3276 TSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQP-ARFQCRVSGT--DLKVSWY 3332
Query: 1823 KDSKSI--AQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQ 1880
K I ++ R T I +A P+D+G Y N+ G+V++ NL+ E +
Sbjct: 3333 SKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES 3392
Query: 1881 LSSRQDTKGCEEIEFSQLIFKEDFL 1905
+ + +EIE F FL
Sbjct: 3393 ILHERIE---QEIEMEMKEFSSSFL 3414
Score = 34.7 bits (78), Expect = 1.0
Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 4/101 (3%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S V D + ISG+PKP +TW K+G + + I+ + + + L + K
Sbjct: 16741 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD---LTTLSIKETHK 16797
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDD 120
+D Y I+ N G S + V +P P DD
Sbjct: 16798 DDGGQYGITVANVVGQKTASIEI-VTLDKPDPPKGPVKFDD 16837
Score = 34.3 bits (77), Expect = 1.4
Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 5/67 (7%)
Query: 39 PKPEVTWYKNGQAIDGSGIISNYEFFENQYIHV-LHLSCCTKNDAAVYQISAKNSFGMIC 97
P P V+W+K+G+ + S ++ +N +I L + + DA +Y I+ +N G
Sbjct: 7917 PVPTVSWHKDGKEVKASDRLT----MKNDHISAHLEVPKSVRADAGIYTITLENKLGSAT 7972
Query: 98 CSASVEV 104
S +V+V
Sbjct: 7973 ASINVKV 7979
Score = 34.3 bits (77), Expect = 1.4
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 6/122 (4%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
+ G+P+P++TW K G+ + + ++ L + + D Y ISAKNS G
Sbjct: 11435 VKGRPEPDITWTKEGKVLVRE---KRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSG 11491
Query: 95 MICCSASVEV---ECSSENPQLSPNLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEE 151
SA V V +N +++ +++ W++ E N I E P ++
Sbjct: 11492 HAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGW 11551
Query: 152 SI 153
SI
Sbjct: 11552 SI 11553
Score = 34.3 bits (77), Expect = 1.4
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 16/152 (10%)
Query: 1729 KKILSRVAALRLKLEEKENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVL 1788
+++ S++ R L E+ SA +K E SL EEK +K K A +L
Sbjct: 26015 REVKSQMTETRESLSSYEH--SASAEMKSAALEEKSL---EEKSTTRK--IKTTLAARIL 26067
Query: 1789 LKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQR----SAGDNSTVSFA 1844
K ++ S + SC + T+ W + + ++ R + ST +
Sbjct: 26068 TKPRSMTVYEGESA--RFSCD-TDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEIS 26124
Query: 1845 IVQASPKDQGLYYCCIKNSYGKVTAEFNLTAE 1876
VQAS D+G Y ++NS GK AEF LT +
Sbjct: 26125 SVQAS--DEGNYSVVVENSEGKQEAEFTLTIQ 26154
Score = 33.1 bits (74), Expect = 3.0
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 7/77 (9%)
Query: 37 GQPKPEVTWYKN-GQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGM 95
G+P PE+TW + G+ D I + + L + C +NDA Y + +NS G
Sbjct: 17553 GRPTPEITWSREEGEFTDKVQIEKGVNYTQ------LSIDNCDRNDAGKYILKLENSSGS 17606
Query: 96 ICCSASVEVECSSENPQ 112
+V+V + PQ
Sbjct: 17607 KSAFVTVKVLDTPGPPQ 17623
Score = 33.1 bits (74), Expect = 3.0
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 9/99 (9%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLR--CIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
PP + + K+ VL+ I+G+P P ++W K+G I+ + E
Sbjct: 19289 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEER---ARTEIISTD 19345
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVEC 106
+L + C + D Y ++ KN G + SV V C
Sbjct: 19346 NHTLLTVKDCIRRDTGQYVLTLKNVAG----TRSVAVNC 19380
Score = 32.7 bits (73), Expect = 4.0
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 35 ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFG 94
I G+P P+ +W K G+ I S I + +L + T+ DA Y I+A N FG
Sbjct: 13906 ILGKPLPKSSWSKAGKDIRPSDIT---QITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962
Score = 32.3 bits (72), Expect = 5.2
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 13/106 (12%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFE-----NQY 68
F+ L + + E S ++ +G P P++ W KN S II +++ + +
Sbjct: 1512 FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKN------SDIIVPHKYPKIRIEGTKG 1565
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFG--MICCSASVEVECSSENPQ 112
L + D+A Y +A N G C +VEVE + P+
Sbjct: 1566 EAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPE 1611
Score = 32.3 bits (72), Expect = 5.2
Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 7/82 (8%)
Query: 15 LSTLLSQKVPEKSDAVLRCI--ISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVL 72
L + ++ + V+R I +SG+P P VTW N + + I + I
Sbjct: 10029 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVI--- 10085
Query: 73 HLSCCTKNDAAVYQISAKNSFG 94
C ++ VY + AKN G
Sbjct: 10086 --KNCQRSHQGVYSLLAKNEAG 10105
Score = 32.3 bits (72), Expect = 5.2
Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 10 PPLCFLSTLLSQKVPEKS--DAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
PP LS + + K+ + L + G+P P V+W K+G + + + +
Sbjct: 12795 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPA---EGIKMAMQR 12851
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+ L L + D+ Y I+A+NS G + ++V
Sbjct: 12852 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 12888
Score = 32.0 bits (71), Expect = 6.8
Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
Query: 10 PPLCFLSTLLSQKVPEKSDAVLRCIIS--GQPKPEVTWYKNGQAIDGSGIISNYEFFE-N 66
PP L L + V ++ A LR ++ G+P+PEV W K GI+++ E
Sbjct: 18607 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK------AEGILTDRAQIEVT 18660
Query: 67 QYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENP 111
+L + T+ D+ Y ++ +N+ G +V V S P
Sbjct: 18661 SSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAP 18705
Score = 31.6 bits (70), Expect = 8.9
Identities = 23/103 (22%), Positives = 41/103 (39%), Gaps = 20/103 (19%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P FL L + + A+ + G+P P VTW+K N + + Y
Sbjct: 3574 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFK-----------ENKQLCTSVYYT 3622
Query: 71 VLH---------LSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
++H ++ + D+ +Y A+N G C+A + V
Sbjct: 3623 IIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 31.6 bits (70), Expect = 8.9
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Query: 1783 GRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQR--SAGDNST 1840
G AP + K+++ ++ + +LSCQ I W + K + Q ++ + D T
Sbjct: 24033 GEAPGIRKEMK-DVTTKLGEAAQLSCQIVG-RPLPDIKWYRFGKELIQSRKYKMSSDGRT 24090
Query: 1841 VSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQ 1880
+ ++ +D+G+Y C N G+V L + Q
Sbjct: 24091 HTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ 24130
Score = 31.6 bits (70), Expect = 8.9
Identities = 34/139 (24%), Positives = 56/139 (40%), Gaps = 15/139 (10%)
Query: 1746 ENIRKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVK 1805
E ++K++A LE S+ H E K E R +K +M +
Sbjct: 26509 EEVKKSAA-----TSLEKSIVHEEIT---KTSQASEEVRTHAEIKAFSTQMSINEGQRLV 26560
Query: 1806 LSCQFAEIHEDSTICWTKDSKSIAQVQ--RSAGDNSTVSFAIVQASPKDQGLYYCCIKNS 1863
L A I + + W + + + R S + I QAS +D+G+ C K
Sbjct: 26561 LK---ANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTK 26617
Query: 1864 YGKVTAEFNLTAEVLKQLS 1882
G V +++LT + K+LS
Sbjct: 26618 EGIVKCQYDLT--LSKELS 26634
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 63.2 bits (152), Expect = 3e-09
Identities = 41/116 (35%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Query: 1 MKDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISN 60
MK S G Q P CFL +V ++A L+C++ G+P P V W K GQ + S +S
Sbjct: 1 MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLS- 59
Query: 61 YEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV-ECSSENPQLSP 115
F + H L L+ DA VY A+N+ G +A+V V E + +P+L P
Sbjct: 60 --FPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQP 113
Score = 40.0 bits (92), Expect = 0.025
Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 6/109 (5%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH--- 70
FL+ SQ V ++ VL C G P+P + W K+G A+D S++ +
Sbjct: 130 FLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPG 189
Query: 71 ---VLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPN 116
L + D+ VY A+N+ G A ++V E+P P+
Sbjct: 190 ASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPD 238
Score = 38.5 bits (88), Expect = 0.072
Identities = 35/145 (24%), Positives = 59/145 (40%), Gaps = 14/145 (9%)
Query: 23 VPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDA 82
V E A RC + G+P+PE+ W+ G+ + Y + + VL + C D
Sbjct: 257 VNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGF--VLKVLYCQAKDR 314
Query: 83 AVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETGTHEEERAN---- 138
+Y +A+NS G + + V + P+L G +H E + N
Sbjct: 315 GLYVCAARNSAGQTLSAVQLHV----KEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIP 370
Query: 139 ----QIDEKEHPYKEEESISPGTPR 159
+ D++ P ++ E I GT R
Sbjct: 371 TAWFREDQRLLPCRKYEQIEEGTVR 395
Score = 33.5 bits (75), Expect = 2.3
Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 4/75 (5%)
Query: 15 LSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHL 74
+S L V E DA RC +S P +VTW +NG + E +N +L L
Sbjct: 1363 VSELTPLTVHEGDDATFRCEVS-PPDADVTWLRNGAVVTPG---PQVEMAQNGSSRILTL 1418
Query: 75 SCCTKNDAAVYQISA 89
C DA + A
Sbjct: 1419 RGCQLGDAGTVTLRA 1433
Score = 32.0 bits (71), Expect = 6.8
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 13/96 (13%)
Query: 1785 APVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSA--------- 1835
APV L +++ + V L+C+ + E T+ W KD ++ +V S+
Sbjct: 127 APVFLTGPRSQ-WVLRGAEVVLTCRAGGLPEP-TLYWEKDGMALDEVWDSSHFALQPGRA 184
Query: 1836 --GDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTA 1869
G ++++ I+ A D G+Y C +N++G A
Sbjct: 185 EDGPGASLALRILAARLPDSGVYVCHARNAHGHAQA 220
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 57.8 bits (138), Expect = 1e-07
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Query: 3 DSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYE 62
D E + PP F+ + K+PE SDAV +C + G P PEV WYK I+ I Y
Sbjct: 5372 DLEVFEMPPR-FIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNI--KYV 5428
Query: 63 FFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICC 98
E + H L + +D+A Y+ A N G C
Sbjct: 5429 ISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAIC 5464
Score = 50.1 bits (118), Expect = 2e-05
Identities = 61/277 (22%), Positives = 108/277 (38%), Gaps = 27/277 (9%)
Query: 4 SEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEF 63
S+ PP + E +L C+ISG+P+P VTW++NG + + ++F
Sbjct: 4151 SDITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQN---QKFQF 4207
Query: 64 FENQYIHVLHLSCCTKNDAAVYQISAKNSFGMI--CCSASVEVECSSENPQLSPNLEDDR 121
E H L++ D+ Y+ A+N+ G + +VE EN Q E+
Sbjct: 4208 EEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPVTYRENSQ----FENIG 4263
Query: 122 DRGWKHETGTHEEERANQIDEKEHPYKEEESISPGTPRSADSSPSKSNHSLSLQSLGNLD 181
+ K+ +++ + + H Y + P TP + S ++ SL+++ +D
Sbjct: 4264 EIYGKYSRDQQLQDQGESV--RAHFY--DYPAGPFTPWTNVKEYSVRDYFQSLETIEQID 4319
Query: 182 ------ISVSSSENPLGVKGTRHTGEAYDPSNTEEI---ANGLLFLNSSHIYEKQD-RCC 231
S + P V G T + P E I A G H+ EK
Sbjct: 4320 QKEQVRCIPSREKIPRFVHGASRTIKISKPIRAEFIQCQAEG----KERHVSEKSKLHQA 4375
Query: 232 HKTVHSMASKFTDGDLNNDGPHDEGLRSSQQNPKVQK 268
TV+ F+D + + ++ G + VQ+
Sbjct: 4376 EGTVYPFVDDFSDVTIKKEIRNNFGKLGRSEKENVQE 4412
Score = 47.8 bits (112), Expect = 1e-04
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 8/111 (7%)
Query: 22 KVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY--IHVLHLSCCTK 79
+V E A RC ++G P+P+V WY NGQ +I + F +Y IH L + C
Sbjct: 1851 RVLEGETARFRCRVTGYPQPKVNWYLNGQ------LIRKSKRFRVRYDGIHYLDIVDCKS 1904
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHETG 130
D +++A+N G+I +E++ + + + R HE G
Sbjct: 1905 YDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPG 1955
Score = 47.8 bits (112), Expect = 1e-04
Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query: 34 IISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNSF 93
+ISG+P+P+++WYK Q + +F + + L L DAAVY AKN +
Sbjct: 3261 VISGRPQPKISWYKEEQLLSTG---FKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDY 3317
Query: 94 GMICCSASVEVE 105
G+ SAS+ VE
Sbjct: 3318 GVATTSASLSVE 3329
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
Query: 5 EGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
EGP R F+ + P + A +C++ G P+P V WYK+G+ + G
Sbjct: 5511 EGPPR----FIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEE--- 5563
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGM 95
H L ++ K+D Y+ A N GM
Sbjct: 5564 SGTGFHNLFITSLVKSDEGEYRCVATNKSGM 5594
Score = 43.9 bits (102), Expect = 0.002
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F L S V E S A ISG P PEV+W+++GQ I S + F + L
Sbjct: 8 FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK-LT 66
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLE 118
+ TK ++ Y + A N G +A + V+ + P L+
Sbjct: 67 IPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ 111
Score = 42.7 bits (99), Expect = 0.004
Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 4/105 (3%)
Query: 5 EGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
E P PP +S L + V E L C ISG P P VTWY+ I+ S +++
Sbjct: 937 EIPVTPPT-LVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESS---IDFQIT 992
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
I L + D+ + SA N G + S + V+ S E
Sbjct: 993 FQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 1037
Score = 42.4 bits (98), Expect = 0.005
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 2/109 (1%)
Query: 2 KDSEGPQRPPL-CFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISN 60
++ GP P F++ + QK+ E V C + G PKP V W K+G + +G
Sbjct: 1071 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT-TGYRYK 1129
Query: 61 YEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
+ + L +S +DA Y I +N G SAS+ E E
Sbjct: 1130 VSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1178
Score = 42.4 bits (98), Expect = 0.005
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
SQ V + SDA R + G+P PE WYKNG I+ S I Y ++ + L + T
Sbjct: 2086 SQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI--YWYWPEDNVCELVIRDVTA 2143
Query: 80 NDAAVYQISAKNSFG 94
D+A + A N G
Sbjct: 2144 EDSASIMVKAINIAG 2158
Score = 42.0 bits (97), Expect = 0.007
Identities = 40/167 (23%), Positives = 65/167 (38%), Gaps = 19/167 (11%)
Query: 7 PQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFEN 66
PQR P FL + SQ+V E C G P+P VTWY N I + N+
Sbjct: 3939 PQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRN---QNFIIHSL 3995
Query: 67 QYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWK 126
+ +L LS + N +G + ++ ++V+ ++ + +
Sbjct: 3996 ENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVP------VF 4049
Query: 127 HETGTHEEERANQIDEKE--HPYKEEE--------SISPGTPRSADS 163
H+ EEE A D+ + HP +E +P P S D+
Sbjct: 4050 HDYLDEEEELALVFDQAKGAHPSMSQEGQTNLHLLKTNPPVPPSGDT 4096
Score = 40.0 bits (92), Expect = 0.025
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 4/107 (3%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S + + ++ E C +SG P P++ WYK+G+ I G +F ++ L
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGRAS-LR 1350
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE--NPQLSPNLE 118
+ D +Y A N G CS + VE ++ P P LE
Sbjct: 1351 IPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLE 1397
Score = 36.6 bits (83), Expect = 0.28
Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1786 PVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSA--GDNSTVSF 1843
P +L+++Q SG C I W K+ + ++ + D +
Sbjct: 3239 PQVLQELQPVTV--QSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 1844 AIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQLSSRQD 1886
+++A P+D +Y C KN YG T +L+ EV + +S Q+
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3339
Score = 32.7 bits (73), Expect = 4.0
Identities = 37/176 (21%), Positives = 66/176 (37%), Gaps = 21/176 (11%)
Query: 1763 TSLSHTEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWT 1822
TS S + E + P + P ++ +Q + E + C+ + D + W
Sbjct: 3322 TSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQP-ARFQCRVSGT--DLKVSWY 3378
Query: 1823 KDSKSI--AQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEV--- 1877
K I ++ R T I +A P+D+G Y N+ G+V++ NL+ E
Sbjct: 3379 SKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES 3438
Query: 1878 -------------LKQLSSRQDTKGCEEIEFSQLIFKEDFLHDSYFGGRLRGQIAT 1920
+K+L S +++ E ED H S R +I++
Sbjct: 3439 ILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISS 3494
Score = 32.3 bits (72), Expect = 5.2
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 13/106 (12%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFE-----NQY 68
F+ L + + E S ++ +G P P++ W KN S II +++ + +
Sbjct: 1558 FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKN------SDIIVPHKYPKIRIEGTKG 1611
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFG--MICCSASVEVECSSENPQ 112
L + D+A Y +A N G C +VEVE + P+
Sbjct: 1612 EAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPE 1657
Score = 32.3 bits (72), Expect = 5.2
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 1/92 (1%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAI-DGSGIISNYEFFENQYIHVL 72
F L + V E V C + P PE+TW+ N + I G I E + + L
Sbjct: 3506 FTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSL 3565
Query: 73 HLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+ D+ Y++ A NS G +AS+ V
Sbjct: 3566 EIKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 55.8 bits (133), Expect = 4e-07
Identities = 261/1297 (20%), Positives = 415/1297 (31%), Gaps = 215/1297 (16%)
Query: 413 RSSRVSKHGPSSPQTGM----TLILGPHQDGTSSVTEQGRYKLPTAPEAAENDYPGIQGE 468
R S S P S T + T GP Q+ T+S + G +P + G +
Sbjct: 2577 RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQEST 2636
Query: 469 TRDSHQAREEFASDNLLNMDESVRETEMKLLSGESENSGMSQCWETAADKRVGGKDLWSK 528
T S S T L + +SG+ + T G S
Sbjct: 2637 TFHS-----------------SPGSTHTTLFPDSTTSSGIVEA-STRVHSSTG-----SP 2673
Query: 529 RGSRKSARVRQPGMKGNPKKPNANLRESTTEGTLHLCSAKESAEPPLTQSDKRETSHTTA 588
R + A PG++G ESTT T H S + PP T + E S T
Sbjct: 2674 RTTLSPASSTSPGLQG----------ESTTFQT-HPASTHTTPSPPSTATAPVEESTTYH 2722
Query: 589 AATGRSSHADARECAISTQAEQEAKTL------QTSTDSVSKEGNTNCKGEGMQVNTLFE 642
+ G S+ + +T E T+ + T S T+ +GE
Sbjct: 2723 RSPG-STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST------- 2774
Query: 643 TSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENA 702
TS++ S T +S + +S P SP T + S ++LG +
Sbjct: 2775 TSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP---RSPTTTLSPASMTSLGVGEESTT 2831
Query: 703 SLAQ----HSEVKPC--TCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVF 756
S +Q HS V P T EE + P + + + + E P F
Sbjct: 2832 SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGE--EPTTF 2889
Query: 757 SRHLPKDARADFREPVAVS---------VASPEPTDTALTLENVCDEPRDREAVCAMECF 807
F E S SP T T L + +
Sbjct: 2890 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS-- 2947
Query: 808 EAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDTE------------LAEGQNKVSDLCSS 855
+G GT S V + +P + TE L+E S
Sbjct: 2948 -SGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 3006
Query: 856 NDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISH--TASEGATGENLAK 913
D TL T + S+ S+ G++ + ST T +S TAS + G A
Sbjct: 3007 PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEAT 3066
Query: 914 VENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTA 973
+ + +S GQ+ + +S G ET LL + + S + TT
Sbjct: 3067 LSPGSTTASSL---GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 3123
Query: 974 TPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIATEVHPAKYLAVSIPEDKHA 1033
TPAS +S L + FQ+ + DT+ T P V + H+
Sbjct: 3124 TPASSTS---------AGLQEESTTFQSWPSSSDTTPSPPGTTAAP-----VEVSTTYHS 3169
Query: 1034 GGTEERFPRASHEKVSQFPSQVQLDHILSGATIKSTKELLCRAPSVPGVPHHVLQLPEGE 1093
PS H + +T E S PG L
Sbjct: 3170 R-----------------PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTAL------ 3206
Query: 1094 GFCSNSPLQVDNLSGDKSQTVDRADFRSYEENFQERGSETKQGVQQQSLSQQGSLSAPDF 1153
F + S V L G+ + + + E GS T G+ ++S + S +PD
Sbjct: 3207 -FPTRSATSV--LVGEPTTSPISS---GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT 3260
Query: 1154 QQS-LPTTSAAQEERNLVPTAHS-PASSREGAGQRSGWGTRVSVVAETAGEEDSQALSNV 1211
S TTS+ E + T+HS P S+ A S VS ++S A +
Sbjct: 3261 TLSPASTTSSGVSEEST--TSHSRPGSTHTTAFPGSTTMPGVS--------QESTASHSS 3310
Query: 1212 PSLSDILLEESKEYRPGNWEAGNKLKIITLEASASEIWPPRQLTNSESKASDGGLIIPDK 1271
P +D L PG+ +AS + P +S +++ L+
Sbjct: 3311 PGSTDTTLS------PGS-------------TTASSLGPESTTFHSGPGSTETTLL---- 3347
Query: 1272 VWAVPDSLKADAVVPELAPSEIAALAHSPEDAESALADSRESHKGEEPTISVHWRSLSSR 1331
PD+ A ++ P + S + L+ + + + E T W +
Sbjct: 3348 ----PDNTTASGLLEASTP-----VHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDT 3398
Query: 1332 GFSQPRLLESSVDPVDEKELSVTDSLSAASETGGKENVNNVSQDQEEKQLKMDHTAFFKK 1391
+ P + V ELS T S +S + ++ + + E+ + +
Sbjct: 3399 TPAPPTTTSAFV------ELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 3452
Query: 1392 FLTCPKILESSVDPIDEISVIEYTRAGKPEPSETTPQGAREGGQSNDGNMGHEAEIQPAI 1451
T P S+ + E S ++ G + P+ G+ + H + I
Sbjct: 3453 --TTPSPARSTTSGLVEESTTYHSSPGSTQTMHF-PESDTTSGRGEESTTSHSSTTH-TI 3508
Query: 1452 LQVPCLQGTILSENRISRSQEGSMK------------QEAEQIQPEEAKTAIWQVLQPSE 1499
P ++ E S GS + E ++ A ++ P+
Sbjct: 3509 SSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPAR 3568
Query: 1500 G------GERIPSGCSIGQIQESS-DGSLGEAEQSKKDKAELISPTSPLSSCLPIMTHAS 1552
GE S S G ++ ++ GS S+K SP SP ++ P T +S
Sbjct: 3569 STTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSS 3628
Query: 1553 LGVDTHNSTGQIHDVPENDIVEPRKRQYVFPVSQKRGTIENERGKPLPSSPDLTRFPCTS 1612
GV ++T H P + P + T + P S D T P ++
Sbjct: 3629 -GVSEESTTS--HSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS----PGSTDTTLLPAST 3681
Query: 1613 SPEGNVTDFLISHKMEEPKIEVLQIGETKPPSSSSSS 1649
+ G+ + SH L G T S S
Sbjct: 3682 TTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQES 3718
Score = 48.1 bits (113), Expect = 9e-05
Identities = 254/1277 (19%), Positives = 408/1277 (31%), Gaps = 185/1277 (14%)
Query: 403 HHSQP--------QEVGVRSSRVSKHGPSSPQTGMTLILGPHQDGTSSVTEQGRYKLPTA 454
+HS P E S R + S T T+ P TS++ E+ +
Sbjct: 1915 YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST--TSALVEEPTSYHSSP 1972
Query: 455 PEAAENDYPGIQGETRDSHQAREEFASDNLLNMDESVRETEMKLLSGESENSGMSQ-CWE 513
A +P + S ++ +S + + +L GES S +S E
Sbjct: 1973 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 2032
Query: 514 TAADKRVGGKDLWSKRGSRKSARVRQPGMKGNPKKPNAN--LRESTTE----GTLHLCSA 567
T A S++ + + R P +P ++ ESTT G+ H +
Sbjct: 2033 TTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 2092
Query: 568 KESAEPPLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQEAKTLQTSTDSVSKEGN 627
+S P S TSH++ +T + + + +Q + + STD+ G+
Sbjct: 2093 PDSTTTP-GLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGS 2151
Query: 628 TNCKGEGMQVNTLFE----------------------------------TSQVPDWSDPP 653
T G + T T+ P S P
Sbjct: 2152 TTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 2211
Query: 654 QVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPC 713
+Q + T +T S S P+ +P +TT S ++ H
Sbjct: 2212 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS-------PGSTPTTHFPASST 2264
Query: 714 TCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVA 773
T G H EK + PD S + E+ + SR P +
Sbjct: 2265 TSG--HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT----SRISPGSTEIT---TLP 2315
Query: 774 VSVASPEPTDTALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQ 833
S +P ++ + T + P + +M G++ T T S G SP
Sbjct: 2316 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST---TSRSQPGSTHSTVSPA 2372
Query: 834 EICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTST 893
+ L+E V + +T T T ++ + + P T T
Sbjct: 2373 S--TTTPGLSEESTTVYSSSPGSTET------TVFPRTPTTSVRGEEPTTFHSRPASTHT 2424
Query: 894 FTLNISHTASEGATGENLA------KVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLS 947
TL + + G T E+ A + +T G+E + +S G T L
Sbjct: 2425 -TLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSP 2483
Query: 948 SENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKPTTLTANNECFQATRETED 1007
+ + E SPS+ +TT P S ++ EK TT + AT
Sbjct: 2484 ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTT--PSLSEKSTTFYTSPRSPDATLSPAT 2541
Query: 1008 TSTVTIATE-----VHPAKYLAVSIPEDKHAGGTEERFPRASHEKVSQFPSQVQLDHILS 1062
T++ ++ E P + P+ G R SH P + +
Sbjct: 2542 TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGL-SRHSTTSHSS----PGSTDTTLLPA 2596
Query: 1063 GATIKSTKELLCRAPSVPGVPHHVLQL---------PEGEGFCSNSPLQVDNLSGDK--S 1111
T + + S PG L E F S+ L D S
Sbjct: 2597 STTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTS 2656
Query: 1112 QTVDRADFRSYEENFQER-----GSETKQGVQQQSLSQQGSLSAPDFQQSLPTTSAAQEE 1166
+ A R + R S T G+Q +S + Q ++ S P+T+ A E
Sbjct: 2657 SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVE 2716
Query: 1167 RNL--------VPTAHSPASS-REGAGQRS---------GWGTRVSVVAETAGEEDSQAL 1208
+ PT H PASS G ++S T S + T+G +S
Sbjct: 2717 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS 2776
Query: 1209 SNVPSLSDILLEESKEYRPGNWEAGNKLKIITLEASASEIWPPRQLTNSESKASDGGLII 1268
P ++I PG EAS + PR T + S AS L +
Sbjct: 2777 RISPGSTEITTLPGSTTTPG-----------LSEASTTFYSSPRSPTTTLSPASMTSLGV 2825
Query: 1269 PDKVW---AVPDSL-----KADAVVPELAPSEIAALAHSPEDAESAL--ADSRESHKGEE 1318
++ + P S A P L+ + SP E+ + + S +GEE
Sbjct: 2826 GEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEE 2885
Query: 1319 PTISVHWRSLSSRGFSQPRLLESSVDPVDEKELSVTDSLSAASETGGKENVNNVSQDQEE 1378
PT + H R S+ E S +E + A+++TG + +E
Sbjct: 2886 PT-TFHSRPASTH---TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEES 2941
Query: 1379 KQLKMDH-----TAFFKKFLTCPKILESSVDPIDEISVIEYTRAGKPEPSETTPQGAREG 1433
T + T + ES+ + S T G P TTP + +
Sbjct: 2942 TTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP----TTPSLSEKS 2997
Query: 1434 GQSNDGNMGHEAEIQPAILQVPCLQGTILSENRISRSQEGSMKQEAEQIQPEEAKTAIWQ 1493
+A + PA + E+ S SQ GS A P+ T+
Sbjct: 2998 TTFYTSPRSPDATLSPA----TTTSSGVSEESSTSHSQPGSTHTTA---FPDSTTTS--- 3047
Query: 1494 VLQPSEGGERIPSGCSIGQIQES-SDGSLGEAEQSKKDKAELISPTSPLSSCLPIMTHAS 1552
E S S G + + S GS + ++ SP ++ LP T S
Sbjct: 3048 ----GLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITS 3103
Query: 1553 ----LGVDTHNSTGQIH 1565
TH+STG +H
Sbjct: 3104 GLVEASTPTHSSTGSLH 3120
Score = 45.4 bits (106), Expect = 6e-04
Identities = 258/1370 (18%), Positives = 439/1370 (32%), Gaps = 173/1370 (12%)
Query: 403 HHSQP--------QEVGVRSSRVSKHGPSSPQTGMTLILGPHQDGTSSVTEQGRYKLPTA 454
+HS P E S R + S T T+ P TS++ E+ +
Sbjct: 3472 YHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPST--TSALVEEPTSYHSSP 3529
Query: 455 PEAAENDYPGIQGETRDSHQAREEFASDNLLNMDESVRETEMKLLSGESENSGMSQ-CWE 513
A +P + S ++ +S + + +L GES S +S E
Sbjct: 3530 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 3589
Query: 514 TAADKRVGGKDLWSKRGSRKSARVRQPGMKGNPKKPNAN--LRESTTE----GTLHLCSA 567
T A S++ + + R P +P ++ ESTT G+ H +
Sbjct: 3590 TTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 3649
Query: 568 KESAEPPLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQEAKTLQTSTDSVSKEGN 627
+S P S TSH++ +T + + + S+Q + + STD+ G+
Sbjct: 3650 PDSTTTP-GLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGS 3708
Query: 628 TNCKGEGMQVNTLFE------TSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEES 681
T G + T T+ PD + + V+ + R S PA S
Sbjct: 3709 TTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTTLSPASSTS 3767
Query: 682 PFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQ 741
P G+ E+ + H T P
Sbjct: 3768 P-------------GLQGESTAFQTHPASTHTTPSPPSTATAP----------------- 3797
Query: 742 SISEANDETMSPGVF-SRHLPKDARAD-FREPVAVSVASPEPTDTALTLENVCDEPRDRE 799
+ E+ SPG + H P + E + +SP+ + T + + R
Sbjct: 3798 -VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 3856
Query: 800 AVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAEGQNKVSDLCSSNDKT 859
+ T T+ P L+E S T
Sbjct: 3857 TTSRIS-----PGSTEITTLPGSTTTP--------------GLSEASTTFYSSPRSPTTT 3897
Query: 860 LEVFFQTQVSETSVSTCKSSKDGN--SVMSPLFTSTFTLNISHT----ASEGATGENLAK 913
L T + ST S+ G+ S +SP T+T L+ T +S G+T
Sbjct: 3898 LSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGST------ 3951
Query: 914 VENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTA 973
E + +P ++T +E+P+ +S L +E++ E P A+ T
Sbjct: 3952 -ETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG 4010
Query: 974 TPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIATEVHPAKYLAVSIPEDKHA 1033
PA+ ++ + E+ TT +++ ++T + E P++ L+ S E
Sbjct: 4011 LPATLTT--ADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSR-LSPSSTETTTL 4067
Query: 1034 GGTEERFPRASHEKVSQFPSQVQLDHILSGATIKST--KELLCRAPSVPGVPHHVLQLPE 1091
G+ P S + + + S D LS AT S+ E + S PG H P+
Sbjct: 4068 PGSPTT-PSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH-TTAFPD 4125
Query: 1092 GE--GFCSNSPLQVDNLSGDKSQTVDRADFRSYEENFQERGSETKQGVQQQSLSQQGSLS 1149
S P + G T+ + Q + G + +L +++
Sbjct: 4126 STTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTIT 4185
Query: 1150 APDFQQSLPTTSAAQEERNLVPTAHSPASSREGAGQRSGWGTRVSVVAETAGEEDSQALS 1209
+ + S PT S+ + T +PASS T +E+S
Sbjct: 4186 SGLVEASTPTHSSTGS----LHTTLTPASS-----------------TSTGLQEESTTFQ 4224
Query: 1210 NVPSLSDILLEESKEYRPGNWEAGNKLKIITLEASASEIWPPRQLTNSESKASDGGLIIP 1269
+ PS SD P + A + +E S + P + AS L
Sbjct: 4225 SWPSSSDTTPS------PPSTTA------VPVEVSTTYHSRPSSTPTTHFSASSTTLGRS 4272
Query: 1270 DKVWAVPDSLKADAVVPELAPSEIAALAHSPEDAESALAD-SRESHKGEEPTISVHWRSL 1328
++ V S A L P+ A E S ++ S E+ T +
Sbjct: 4273 EESTTVHSSPGATGTA--LFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEK 4330
Query: 1329 SSRGFSQPRLLESSVDPVDEKELSVTDSLSAASETGGKENVNNVSQDQEEKQLKMDHTAF 1388
S+ +S PR ++++ P V++ + + G + + + TA
Sbjct: 4331 STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTAS 4390
Query: 1389 FKKFLTCPKILESSVDPIDEISVIEYTRAGKPEPSETT--PQGAREGGQSNDGNMGHEAE 1446
+ L + T P +ETT P G H +
Sbjct: 4391 HSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSST 4450
Query: 1447 IQPAILQVPCLQGTILSENRISRSQEGSMKQEAEQIQPEEAKTAIWQVLQPSEGGERIPS 1506
P P T E+ +S S P +A ++ S G PS
Sbjct: 4451 GSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPA---PPTTTSAFVELSTTSHGS---PS 4504
Query: 1507 GCSIGQIQESSDGSLGEAEQS----KKDKAELISPTSPLSSCLPIMTHASLGVDTHNSTG 1562
SS +LG +E+S A +P+ S+ ++ ++ + ST
Sbjct: 4505 STPTTHFSASST-TLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQ 4563
Query: 1563 QIHDVPENDIVEPRKRQYVFPVSQKRGTIENERGKPL------------PSSPDLTRFPC 1610
+H PE++ R + S TI + P S T FP
Sbjct: 4564 TMH-FPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPD 4622
Query: 1611 TSSPEGNVTDFLISHKMEEPKIEV---------LQIGETKPPSSSSSSAKTLAFISGERE 1661
+S+ G + SH ++ + + +GE+ SS S +T A
Sbjct: 4623 SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT 4682
Query: 1662 ---LEKAPKLLQDPCQKGTLGCAKKSREREKSLEARAGKSPGTLTAVTGS 1708
EK+ P T + S +S E+ S TA T S
Sbjct: 4683 PGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 4732
Score = 42.0 bits (97), Expect = 0.007
Identities = 247/1261 (19%), Positives = 394/1261 (31%), Gaps = 227/1261 (18%)
Query: 545 NPKKPNANLRESTTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADARECAI 604
+P+ P+A L +TT + S++ TSH+ +T ++ D+ +
Sbjct: 1446 SPRSPDATLSPATTTSS--------------GVSEESSTSHSQPGSTHTTAFPDSTTTSD 1491
Query: 605 STQAEQEAKTLQTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQETVRET 664
+Q + + Q ST++ G+T G Q T S P + +T
Sbjct: 1492 LSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH--------SSPGDTETTLLPDDT 1543
Query: 665 ISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQD 724
I+ + A + T T + S G+ +E+ +
Sbjct: 1544 ITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTF-------------------- 1583
Query: 725 RDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVA-SPEPTD 783
QS ++D T SP P A PV VS P+
Sbjct: 1584 ----------------QSWPSSSDTTPSP-------PGTTAA----PVEVSTTYHSRPSS 1616
Query: 784 TALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDS----LVGRPVDKYSPQEICSVD 839
T T + R G GT S LVG P SP S +
Sbjct: 1617 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT--SPISSGSTE 1674
Query: 840 TELAEGQNKVSDLCS----------SNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPL 889
T G + L S D TL T + ST S+ G++ +
Sbjct: 1675 TTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 1734
Query: 890 FTSTFTLNISHTA-----SEGATGENLAK---VENSTYPLASTVHAGQEQ------PSPS 935
ST +S + S G+T L+ +S P ++T H+ P +
Sbjct: 1735 PGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNT 1794
Query: 936 NSGGLDE--TQLLSSENNPLVQFKEGGDKSPS---------PSAADTT-ATPASYSSIVS 983
+ GL E T + SS +P G + PS+ DT A P + S+ V
Sbjct: 1795 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVE 1854
Query: 984 F-------PWEKPTT-LTANNECFQATRE--TEDTSTVTIATEVHPAKYLAVSIPEDKHA 1033
P PTT +A++ + E T +S V AT PA+ + E+ A
Sbjct: 1855 LSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTA 1914
Query: 1034 GGTEERFPRASHEKVSQFPSQVQLDHILSGATIKSTKELLCRAPSVPGVPHHVLQLPEGE 1093
+ P Q H +T E + S H + P
Sbjct: 1915 YHSS--------------PGSTQTMHFPESSTASGRSEESRTSHS--STTHTISSPPSTT 1958
Query: 1094 GFCSNSPLQVDNLSGDKSQTVDRADFRSYEENFQERGSETKQGVQQQSLSQQGSLSAPDF 1153
P + G + T + ++ G + S G++ P
Sbjct: 1959 SALVEEPTSYHSSPGSTATT-------HFPDSSTTSGRSEESTASHSSQDATGTIVLP-- 2009
Query: 1154 QQSLPTTSAAQEERNLVPTAHSPASSREGAGQRSGWG-TRVSVVAETAGEEDSQALSNVP 1212
+ TTS E P + + G + G + S ++ + LS
Sbjct: 2010 --ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPAS 2067
Query: 1213 SLSDILLEES--KEYRPGNWEAGNKLKIITLEASASEIWPPRQLTNSESKASDGGLIIPD 1270
+ S + EES RPG+ T S P ++ S +S G
Sbjct: 2068 TTSSGVSEESTTSHSRPGSTH--------TTAFPDSTTTPGLSRHSTTSHSSPGST---- 2115
Query: 1271 KVWAVPDSLKADAVVPELAPSEIAALAHS-PEDAESALADSRESHKGEEPTISVHWRSLS 1329
D+ A PS+ + +HS P ++AL+ T ++ + S
Sbjct: 2116 ------DTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGS--------TTALSFGQES 2161
Query: 1330 SRGFSQPRLLESSVDPVDEKELSVTDSLSAASETGGKENVNNVSQDQEEKQLKMDHTAFF 1389
+ S P +++ P + ++ + + G L+ + TAF
Sbjct: 2162 TTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQ 2221
Query: 1390 K---KFLTCPKILESSVDPIDEISVIEYTRAGKPEPSETTPQGAREGGQSNDGNMGHEAE 1446
T P ++ P++E + Y R+ P+ P + G S + H +
Sbjct: 2222 THPASTHTTPSPPSTATAPVEESTT--YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS- 2278
Query: 1447 IQPAILQVPCLQGTILSENRISRSQEGSMKQEAEQIQPEEAKTAIWQVLQP--SEGGERI 1504
P GT S + S G E T P SE
Sbjct: 2279 --------PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 2330
Query: 1505 PSG--CSIGQIQESSDGSLGEAEQSKKDKAE---LISPTSPLSSCLPIMTHASLGVDTHN 1559
S + +S SLG E+S +++ S SP S+ P ++ S V + +
Sbjct: 2331 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 2390
Query: 1560 ----STGQIHDVPENDIVEPRKRQYVFPVSQKRGTIENERGKPLPSSPDLTRFPCTSSPE 1615
T P + + + T+ E + + T FP SP
Sbjct: 2391 PGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP--GSPA 2448
Query: 1616 GNVTDFLISHKMEEPKIEVLQIGE--TKPPSSSSSSAKTLA----FISGERELEKAPKLL 1669
T + + +GE T PSSS S+ TL+ SG +L
Sbjct: 2449 STQTGLPAT-------LTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLS 2501
Query: 1670 QDPCQKGTL-GCAKKSREREKSL-------EARAGKSPGTLTAVTGSEEVKRKPEAPGSG 1721
+ TL G EKS A SP T T+ SEE PGS
Sbjct: 2502 PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGST 2561
Query: 1722 H 1722
H
Sbjct: 2562 H 2562
Score = 40.8 bits (94), Expect = 0.015
Identities = 170/821 (20%), Positives = 270/821 (32%), Gaps = 151/821 (18%)
Query: 920 PLAST--VHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPAS 977
P ST V G PSP +SG ++ T L S P + K S SP + DTT PAS
Sbjct: 596 PAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYS-SPRSPDTTHLPAS 654
Query: 978 YSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIATEVHPAKYLAVSIPEDKHAGGTE 1037
+S + +E+++T + P + P G T
Sbjct: 655 MTS---------------------SGVSEESTT----SHSRPGSTHTTAFP-----GST- 683
Query: 1038 ERFPRASHEKVSQFPSQVQLDHILS-GATIKSTKELLCRAPSVPGVPHHVLQLPEGEGFC 1096
P S E + S D LS G+T S+ G + G
Sbjct: 684 -TMPGLSQESTASHSSPGPTDTTLSPGSTTASSL----------GPEYTTFHSRPGS--- 729
Query: 1097 SNSPLQVDNLSGD---KSQTVDRADFRSYEENFQERGSETKQGVQQQSLSQQGSLSAPDF 1153
+ + L DN + ++ + RS GS T+QG +S + S+ D
Sbjct: 730 TETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQG---ESTTFHSWPSSKDT 786
Query: 1154 QQSLPTTSAAQEERNLVPTAHSPASSREGAGQRSGWGTRVSVVAETAGEEDSQALSNVPS 1213
+ + PTT++A E + T+H SS T +S + T+G
Sbjct: 787 RPAPPTTTSAFVEPS--TTSHGSPSSIP--------TTHISARSTTSG------------ 824
Query: 1214 LSDILLEESKEYR--PGNWEAGNKLKIITLEASASEIWPPRQLTNSESKASDGGLIIPDK 1271
L+EES Y PG+ + T+ S+ R ++ S +S
Sbjct: 825 ----LVEESTTYHSSPGSTQ--------TMHFPESDTTSGRGEESTTSHSS-----TTHT 867
Query: 1272 VWAVPDSLKADAVVPELAPSE--IAALAHSPEDAESA--LADSRESHKGEEPTISVHWRS 1327
+ + P + A P S A H P+ + ++ +S SH ++ T ++
Sbjct: 868 ISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI---V 924
Query: 1328 LSSRGFSQPRLLESSVDPVDEKELSVTDSLSAASETGGKENVNNVSQDQEEKQLKMDHTA 1387
L +R + L ES+ P+ + T +L ++ T G L T
Sbjct: 925 LPARSTTSVLLGESTTSPISSGSMETT-ALPGSTTTPG---------------LSERSTT 968
Query: 1388 FFKKFLTCPKILESSVDPIDEISVIEYTRAGKPEPSETT--PQGAREGGQSNDGNMGHEA 1445
F + L + +S T +P + TT P G S H +
Sbjct: 969 FHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 1028
Query: 1446 EIQPAILQVPCLQGTILSENRISRSQEGSMKQEAEQIQPEEAKTAIWQVLQPSEGGERIP 1505
P L + + S + T Q S P
Sbjct: 1029 ---PGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNP 1085
Query: 1506 SGCSIGQIQESSDGSLGEAEQSKKDKAELISP---TSPLSSCLPIMTHASLGVDTHNSTG 1562
+S+ S G E S + + SP SP SS P + S TH ++
Sbjct: 1086 GSTHTTLFPDSTTSS-GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 1144
Query: 1563 QIHDVPENDIVEPRKRQYVFPVSQKRGTIENERGKPLPSSPDLTRFPCTSSPEGNVTDFL 1622
P + P + + S P S T FP +S+ G+
Sbjct: 1145 HTTPSPPSTATAPVEESTTYHRS--------------PGSTPTTHFPASSTTSGHSEKST 1190
Query: 1623 ISHKMEEPKIEVLQIGETKPPSSSSSSAKTLAFISGERELEKAPKLLQDPCQKGTLGCAK 1682
I H + G T PSS+ S+ + R + ++ P T G ++
Sbjct: 1191 IFHSSPDAS------GTT--PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSE 1242
Query: 1683 KSREREKSLEA-RAGKSPGTLTAVTGSEEVKRKPEAPGSGH 1722
S S + SP ++T++ EE PGS H
Sbjct: 1243 ASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTH 1283
Score = 40.8 bits (94), Expect = 0.015
Identities = 164/850 (19%), Positives = 275/850 (32%), Gaps = 128/850 (15%)
Query: 403 HHSQP--------QEVGVRSSRVSKHGPSSPQTGMTLILGPHQDGTSSVTEQGRYKLPTA 454
+HS P E S R + S T T+ P TS++ E+ +
Sbjct: 832 YHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPST--TSALVEEPTSYHSSP 889
Query: 455 PEAAENDYPGIQGETRDSHQAREEFASDNLLNMDESVRETEMKLLSGESENSGMSQ-CWE 513
A +P + S ++ +S + + +L GES S +S E
Sbjct: 890 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 949
Query: 514 TAADKRVGGKDLWSKRGSRKSARVRQPGMKGNPKKPNAN--LRESTTE----GTLHLCSA 567
T A S+R + + R P +P ++ ESTT G+ H +
Sbjct: 950 TTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAF 1009
Query: 568 KESAEPPLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQEAKTLQTSTDSVSKEGN 627
+S P S TSH++ +T + + + +Q + + STD+ G+
Sbjct: 1010 PDSTTTP-GLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGS 1068
Query: 628 TNCKGEGMQVNTLFE----------------------------------TSQVPDWSDPP 653
T G + T T+ P S P
Sbjct: 1069 TTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 1128
Query: 654 QVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPC 713
+Q + T +T S S P+ +P +TT S ++ H
Sbjct: 1129 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS-------PGSTPTTHFPASST 1181
Query: 714 TCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVA 773
T G H EK + PD S + E+ + SR P +
Sbjct: 1182 TSG--HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT----SRISPGSTEIT---TLP 1232
Query: 774 VSVASPEPTDTALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQ 833
S +P ++ + T + P + +M G++ T T S G SP
Sbjct: 1233 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST---TSRSQPGSTHSTVSPA 1289
Query: 834 EICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTST 893
T + + SS T +T V S +T ++ + S ++
Sbjct: 1290 ST----TTPGLSEESTTVYSSSRGST-----ETTVFPHSTTTSVHGEEPTTFHSRPASTH 1340
Query: 894 FTLNISHTASEGATGENLA------KVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLS 947
TL + + G T E+ A + +T G+E + +S G T+L
Sbjct: 1341 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSP 1400
Query: 948 SENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKPTT--LTANNECFQATRET 1005
+ + E SPS+ +TT P S PTT L+ + F + +
Sbjct: 1401 ARSTTSGLVGESTPSRLSPSSTETTTLPGS-----------PTTPSLSEKSTTFYTSPRS 1449
Query: 1006 EDTSTVTIATEVHPAKYLAVSIPEDKHAGGTEERFPRASHEKVSQFPSQVQLDHILSGAT 1065
D + + PA + + E+ T P ++H + FP + T
Sbjct: 1450 PDAT-------LSPATTTSSGVSEE---SSTSHSQPGSTH--TTAFPDSTTTSDLSQEPT 1497
Query: 1066 IKSTKELLCRAPSVPG------VPHHVLQLPEGEGFCSNSPLQVDNLSGD--KSQTVDRA 1117
+ + A PG + G + L D ++ ++ T +
Sbjct: 1498 TSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHS 1557
Query: 1118 DFRSYEENFQERGSETKQGVQQQSLSQQGSLSAPDFQQSLPTTSAAQEE--------RNL 1169
S S T G+Q++S + Q S+ D S P T+AA E +
Sbjct: 1558 STGSLHTTLTP-ASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSS 1616
Query: 1170 VPTAHSPASS 1179
PT H ASS
Sbjct: 1617 TPTTHFSASS 1626
Score = 40.0 bits (92), Expect = 0.025
Identities = 166/802 (20%), Positives = 261/802 (32%), Gaps = 109/802 (13%)
Query: 422 PSSPQTGMTLILGPHQDGTSSVT-EQGRYKLPTAPEAAENDYPGIQGETRDSHQAREEFA 480
P+S QTG+ L G S T T A + G+ GE+ S
Sbjct: 2447 PASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRL------ 2500
Query: 481 SDNLLNMDESVRETEMKLLSGESENSGMSQCWET------AADKRVGGKDLWSKRGSRKS 534
S TE L G +S+ T + D + S S +S
Sbjct: 2501 ---------SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 2551
Query: 535 ARVR-QPGMKGNPKKPNANLRESTTEGTLHLCSAKESAEPPL-----TQSDKRETSHTTA 588
+ QPG P++ + + S+ S + L T S + S T+
Sbjct: 2552 STSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 2611
Query: 589 AATGRSSHADARECAISTQAEQEAKTLQTST---------DSVSKEGNTNCKGEGMQVNT 639
++ G + A + + QE+ T +S DS + G
Sbjct: 2612 SSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 2671
Query: 640 LFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHK 699
T+ P S P +Q + T +T S S P+ +P +TT S
Sbjct: 2672 SPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRS------- 2724
Query: 700 ENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVFSRH 759
++ H T G H EK + PD S + E+ + SR
Sbjct: 2725 PGSTPTTHFPASSTTSG--HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT----SRI 2778
Query: 760 LPKDARADFREPVAVSVASPEPTDTALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTI 819
P + S +P ++ + T + P + +M G++ T T
Sbjct: 2779 SPGSTEIT---TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST---TS 2832
Query: 820 DSLVGRPVDKYSPQEICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSS 879
S G SP T + + SS T +T V S +T
Sbjct: 2833 RSQPGSTHSTVSPAST----TTPGLSEESTTVYSSSPGST-----ETTVFPRSTTTSVRG 2883
Query: 880 KDGNSVMSPLFTSTFTLNISHTASEGATGENLA------KVENSTYPLASTVHAGQEQPS 933
++ + S ++ TL + + G T E+ A + +T G+E +
Sbjct: 2884 EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT 2943
Query: 934 PSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKPTTLT 993
+S G T L + + E SPS+ +TT P S ++ EK TT
Sbjct: 2944 FPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTT--PSLSEKSTTFY 3001
Query: 994 ANNECFQATRETEDTSTVTIATE-----VHPAKYLAVSIPEDKHAGGTEERFPRASHEKV 1048
+ AT T++ ++ E P + P+ G + P ASH
Sbjct: 3002 TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQE-PTASHS-- 3058
Query: 1049 SQFPSQVQLDHILSGATIKSTKELLCRAPSVPGVPHHVLQLPEG---EGFCSNSPLQVDN 1105
SQ ++ L T S + S PG L LP+ G S +
Sbjct: 3059 SQGSTEATLSP--GSTTASSLGQQSTTFHSSPGDTETTL-LPDDTITSGLVEAS-TPTHS 3114
Query: 1106 LSGDKSQTVDRADFRSYEENFQERGSETKQGVQQQSLSQQGSLSAPDFQQSLPTTSAAQE 1165
+G T+ A S T G+Q++S + Q S+ D S P T+AA
Sbjct: 3115 STGSLHTTLTPA-------------SSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPV 3161
Query: 1166 E--------RNLVPTAHSPASS 1179
E + PT H ASS
Sbjct: 3162 EVSTTYHSRPSSTPTTHFSASS 3183
>gi|140560917 myomesin 1 isoform b [Homo sapiens]
Length = 1589
Score = 55.1 bits (131), Expect = 7e-07
Identities = 32/86 (37%), Positives = 42/86 (48%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S V EK + L C I+G P+P VTWYKN I+ Y +H L ++ C
Sbjct: 285 SHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDF 344
Query: 80 NDAAVYQISAKNSFGMICCSASVEVE 105
D A Y+ SA N G + ASV V+
Sbjct: 345 EDTAQYRASAMNVKGELSAYASVVVK 370
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/79 (30%), Positives = 40/79 (50%)
Query: 1803 NVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKN 1862
NV L C+ A I +++ I W KD + I+ ++ + + I + S KD G+Y +K+
Sbjct: 1277 NVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKD 1336
Query: 1863 SYGKVTAEFNLTAEVLKQL 1881
GK + L E K+L
Sbjct: 1337 DRGKDKSRLKLVDEAFKEL 1355
Score = 33.5 bits (75), Expect = 2.3
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIIS-NYEFFENQYIHVLHLSCCTKNDAAVYQISA 89
L C + G P PEV+W KN +A+ + +E Y + +S D+ Y +
Sbjct: 1496 LTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA---DSGKYGLVV 1552
Query: 90 KNSFGMICCSASVEVECSSENPQLS 114
KN +G +V V E +++
Sbjct: 1553 KNKYGSETSDFTVSVFIPEEEARMA 1577
Score = 32.3 bits (72), Expect = 5.2
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 7/61 (11%)
Query: 1819 ICWTKDSKSIAQ-----VQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNL 1873
+ W K+ K++A ++ AG T F I S D G Y +KN YG T++F +
Sbjct: 1508 VSWLKNEKALASDDHCNLKFEAG--RTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTV 1565
Query: 1874 T 1874
+
Sbjct: 1566 S 1566
>gi|140560919 myomesin 1 isoform a [Homo sapiens]
Length = 1685
Score = 55.1 bits (131), Expect = 7e-07
Identities = 32/86 (37%), Positives = 42/86 (48%)
Query: 20 SQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTK 79
S V EK + L C I+G P+P VTWYKN I+ Y +H L ++ C
Sbjct: 285 SHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDF 344
Query: 80 NDAAVYQISAKNSFGMICCSASVEVE 105
D A Y+ SA N G + ASV V+
Sbjct: 345 EDTAQYRASAMNVKGELSAYASVVVK 370
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/79 (30%), Positives = 40/79 (50%)
Query: 1803 NVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKN 1862
NV L C+ A I +++ I W KD + I+ ++ + + I + S KD G+Y +K+
Sbjct: 1373 NVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKD 1432
Query: 1863 SYGKVTAEFNLTAEVLKQL 1881
GK + L E K+L
Sbjct: 1433 DRGKDKSRLKLVDEAFKEL 1451
Score = 33.5 bits (75), Expect = 2.3
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIIS-NYEFFENQYIHVLHLSCCTKNDAAVYQISA 89
L C + G P PEV+W KN +A+ + +E Y + +S D+ Y +
Sbjct: 1592 LTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA---DSGKYGLVV 1648
Query: 90 KNSFGMICCSASVEVECSSENPQLS 114
KN +G +V V E +++
Sbjct: 1649 KNKYGSETSDFTVSVFIPEEEARMA 1673
Score = 32.3 bits (72), Expect = 5.2
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 7/61 (11%)
Query: 1819 ICWTKDSKSIAQ-----VQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNL 1873
+ W K+ K++A ++ AG T F I S D G Y +KN YG T++F +
Sbjct: 1604 VSWLKNEKALASDDHCNLKFEAG--RTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTV 1661
Query: 1874 T 1874
+
Sbjct: 1662 S 1662
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 54.3 bits (129), Expect = 1e-06
Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S SQ+V E RC +SG PKPEV W+ G + + E +E+ H L
Sbjct: 416 FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE--GSIEVYEDAGSHYLC 473
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
L D+ Y +A N+ G + CS +++VE
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
Score = 48.9 bits (115), Expect = 5e-05
Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 6/91 (6%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S L V E D VL+C + G P P +TW NGQ I + E LH
Sbjct: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE------LH 569
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+ D Y A+N+ G + CSA V V
Sbjct: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Score = 46.2 bits (108), Expect = 3e-04
Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F T+ +V E S A C I G P PEV W+K+ Q+I S ++ E+ ++
Sbjct: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF-QIDYDEDGNCSLII 1818
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
C +DA Y A NS G C+A + VE E
Sbjct: 1819 SDVCGDDDAK-YTCKAVNSLGEATCTAELIVETMEE 1853
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 19/130 (14%)
Query: 1764 SLSHTEEKQDPKKP-SCKR--------------EGRAPVLLKKIQAEMFPEHSGNVKLSC 1808
S S E K+D K +CKR +G AP +K+Q ++ + L C
Sbjct: 1061 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLLLQC 1119
Query: 1809 QFAEIHEDSTICWTKDSKSIAQVQRS--AGDNSTVSFAIVQASPKDQGLYYCCIKNSYGK 1866
Q + +TI WT + K++ + + + S S +I +A P+D+GLY C KN G+
Sbjct: 1120 QVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1178
Query: 1867 VTAEFNLTAE 1876
+T +
Sbjct: 1179 AECSCQVTVD 1188
Score = 42.0 bits (97), Expect = 0.007
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 4/100 (4%)
Query: 7 PQRPPL-CFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFE 65
P +P FL L KV + S + +SG P PEV W NG I S ++ F +
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES---EDFHFEQ 673
Query: 66 NQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
H L + D Y A NS G + A + V+
Sbjct: 674 RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Score = 41.2 bits (95), Expect = 0.011
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F+S S ++ C I+G P P V W ++G+A+ ++E +N+ + L
Sbjct: 723 FISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKD--TGHFEVLQNEDVFTLV 780
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSS 108
L A Y+I KN G C S+ ++ SS
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSS 815
Score = 40.8 bits (94), Expect = 0.015
Identities = 36/144 (25%), Positives = 57/144 (39%), Gaps = 10/144 (6%)
Query: 33 CIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNS 92
C I+G+P+P+VTW K + S +S E + VL + ++D VY N
Sbjct: 182 CKITGRPQPQVTWLKGNVPLQPSARVS---VSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
Query: 93 FGMICCSASVEVE-CSSENPQLSPNLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEE 151
G SA + ++ S N + K T +E +++D E K +
Sbjct: 239 SGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE--SKLDSLEAAAKSKN 296
Query: 152 SISP----GTPRSADSSPSKSNHS 171
SP P +A+S P S
Sbjct: 297 CSSPQRGGSPPWAANSQPQPPRES 320
Score = 35.0 bits (79), Expect = 0.80
Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 7/124 (5%)
Query: 2 KDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNY 61
K SE P F L V E +L+C +S P + W NG+ + + I
Sbjct: 1089 KRSESQGTAP-AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-- 1145
Query: 62 EFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE--CSSENPQLSPNLED 119
+ + + + D +Y+ AKN G CS V V+ +SEN + +P ++
Sbjct: 1146 -LSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK-APEMKS 1203
Query: 120 DRDR 123
R +
Sbjct: 1204 RRPK 1207
Score = 34.3 bits (77), Expect = 1.4
Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 23 VPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSG---IISNYEFFENQYIHVLHLSCCTK 79
+ E + A + G P+P+VTW++NGQ I G + + IH +H +
Sbjct: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH-----E 98
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECS 107
D Y A N G + + VE S
Sbjct: 99 EDRGKYTCEATNGSGARQVTVELTVEGS 126
Score = 32.0 bits (71), Expect = 6.8
Identities = 47/241 (19%), Positives = 93/241 (38%), Gaps = 30/241 (12%)
Query: 1670 QDPCQKGTLGCAKKSREREKSLEARAGKSPGTLTAVTGSEEVKRKPEAPGSGHLAEGVKK 1729
Q P + C R ++ + S TL A V+ +P APG G L+ ++
Sbjct: 315 QPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA----RVQPEPRAPGLGVLSPSGEE 370
Query: 1730 KILSRVAALRLKLEEKENIRKNSAFLKKMPKLETS--LSHTEEKQDPKKPSCKREGRAPV 1787
+ ++ + + F + P L + +S ++ P + +R+ P
Sbjct: 371 R-------------KRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEG--QRDSAFPK 415
Query: 1788 LLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSAG---DNSTVSFA 1844
K Q++ E+ VK C+ + I + + W + + + + S D +
Sbjct: 416 FESKPQSQEVKENQ-TVKFRCEVSGIPKPE-VAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 1845 IVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQL----SSRQDTKGCEEIEFSQLIF 1900
+++A +D G Y C N+ G+++ + L E L + S K C IE +
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
Query: 1901 K 1901
+
Sbjct: 534 Q 534
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 54.3 bits (129), Expect = 1e-06
Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S SQ+V E RC +SG PKPEV W+ G + + E +E+ H L
Sbjct: 416 FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE--GSIEVYEDAGSHYLC 473
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
L D+ Y +A N+ G + CS +++VE
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
Score = 48.9 bits (115), Expect = 5e-05
Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 6/91 (6%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S L V E D VL+C + G P P +TW NGQ I + E LH
Sbjct: 516 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE------LH 569
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+ D Y A+N+ G + CSA V V
Sbjct: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Score = 46.2 bits (108), Expect = 3e-04
Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F T+ +V E S A C I G P PEV W+K+ Q+I S ++ E+ ++
Sbjct: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF-QIDYDEDGNCSLII 1869
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
C +DA Y A NS G C+A + VE E
Sbjct: 1870 SDVCGDDDAK-YTCKAVNSLGEATCTAELIVETMEE 1904
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 19/130 (14%)
Query: 1764 SLSHTEEKQDPKKP-SCKR--------------EGRAPVLLKKIQAEMFPEHSGNVKLSC 1808
S S E K+D K +CKR +G AP +K+Q ++ + L C
Sbjct: 1061 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLLLQC 1119
Query: 1809 QFAEIHEDSTICWTKDSKSIAQVQRS--AGDNSTVSFAIVQASPKDQGLYYCCIKNSYGK 1866
Q + +TI WT + K++ + + + S S +I +A P+D+GLY C KN G+
Sbjct: 1120 QVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1178
Query: 1867 VTAEFNLTAE 1876
+T +
Sbjct: 1179 AECSCQVTVD 1188
Score = 42.0 bits (97), Expect = 0.007
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 4/100 (4%)
Query: 7 PQRPPL-CFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFE 65
P +P FL L KV + S + +SG P PEV W NG I S ++ F +
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES---EDFHFEQ 673
Query: 66 NQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
H L + D Y A NS G + A + V+
Sbjct: 674 RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Score = 41.2 bits (95), Expect = 0.011
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F+S S ++ C I+G P P V W ++G+A+ ++E +N+ + L
Sbjct: 723 FISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKD--TGHFEVLQNEDVFTLV 780
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSS 108
L A Y+I KN G C S+ ++ SS
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSS 815
Score = 40.8 bits (94), Expect = 0.015
Identities = 36/144 (25%), Positives = 57/144 (39%), Gaps = 10/144 (6%)
Query: 33 CIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNS 92
C I+G+P+P+VTW K + S +S E + VL + ++D VY N
Sbjct: 182 CKITGRPQPQVTWLKGNVPLQPSARVS---VSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
Query: 93 FGMICCSASVEVE-CSSENPQLSPNLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEE 151
G SA + ++ S N + K T +E +++D E K +
Sbjct: 239 SGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE--SKLDSLEAAAKSKN 296
Query: 152 SISP----GTPRSADSSPSKSNHS 171
SP P +A+S P S
Sbjct: 297 CSSPQRGGSPPWAANSQPQPPRES 320
Score = 35.0 bits (79), Expect = 0.80
Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 7/124 (5%)
Query: 2 KDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNY 61
K SE P F L V E +L+C +S P + W NG+ + + I
Sbjct: 1089 KRSESQGTAP-AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-- 1145
Query: 62 EFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE--CSSENPQLSPNLED 119
+ + + + D +Y+ AKN G CS V V+ +SEN + +P ++
Sbjct: 1146 -LSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK-APEMKS 1203
Query: 120 DRDR 123
R +
Sbjct: 1204 RRPK 1207
Score = 34.3 bits (77), Expect = 1.4
Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 23 VPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSG---IISNYEFFENQYIHVLHLSCCTK 79
+ E + A + G P+P+VTW++NGQ I G + + IH +H +
Sbjct: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH-----E 98
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECS 107
D Y A N G + + VE S
Sbjct: 99 EDRGKYTCEATNGSGARQVTVELTVEGS 126
Score = 32.0 bits (71), Expect = 6.8
Identities = 47/241 (19%), Positives = 93/241 (38%), Gaps = 30/241 (12%)
Query: 1670 QDPCQKGTLGCAKKSREREKSLEARAGKSPGTLTAVTGSEEVKRKPEAPGSGHLAEGVKK 1729
Q P + C R ++ + S TL A V+ +P APG G L+ ++
Sbjct: 315 QPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA----RVQPEPRAPGLGVLSPSGEE 370
Query: 1730 KILSRVAALRLKLEEKENIRKNSAFLKKMPKLETS--LSHTEEKQDPKKPSCKREGRAPV 1787
+ ++ + + F + P L + +S ++ P + +R+ P
Sbjct: 371 R-------------KRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEG--QRDSAFPK 415
Query: 1788 LLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICWTKDSKSIAQVQRSAG---DNSTVSFA 1844
K Q++ E+ VK C+ + I + + W + + + + S D +
Sbjct: 416 FESKPQSQEVKENQ-TVKFRCEVSGIPKPE-VAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 1845 IVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVLKQL----SSRQDTKGCEEIEFSQLIF 1900
+++A +D G Y C N+ G+++ + L E L + S K C IE +
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
Query: 1901 K 1901
+
Sbjct: 534 Q 534
>gi|153792294 myopalladin [Homo sapiens]
Length = 1320
Score = 54.3 bits (129), Expect = 1e-06
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Query: 5 EGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
E P P F L S++VPE + L CI+ G P P+V WY G+ ++ S +
Sbjct: 262 EEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENS---PDIHIV 318
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE-CSSENPQLSPNLED 119
+ +H L ++ + D Y A N +G SA + +E SS + + PN E+
Sbjct: 319 QAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEE 374
Score = 41.6 bits (96), Expect = 0.009
Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 23/113 (20%)
Query: 22 KVPEKSDAVLRCIISGQPKPEVTWYKNGQAI-----------DGSGIISNYEFFENQYIH 70
+V E S C I G P P+V W+K+G+ I +G G S
Sbjct: 955 RVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCS----------- 1003
Query: 71 VLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDR 123
LH+ T +D Y I A N G I CS + V+ +L+ + R R
Sbjct: 1004 -LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGR 1055
Score = 40.8 bits (94), Expect = 0.015
Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 15 LSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHL 74
L L + VPE L C + G P P W K+ + I + + Y +L +
Sbjct: 1175 LEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLL-I 1233
Query: 75 SCCTKNDAAVYQISAKNSFGMICCSASVEV 104
K+DA Y +SAKN G++ C+A +++
Sbjct: 1234 QPAKKSDAGWYTLSAKNEAGIVSCTARLDI 1263
Score = 39.7 bits (91), Expect = 0.033
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Query: 31 LRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAK 90
L C +SG P PE+TW NGQ + S+ +H L + T+ DA Y+ A
Sbjct: 1092 LDCKVSGLPPPELTWLLNGQPVLPDA--SHKMLVRETGVHSLLIDPLTQRDAGTYKCIAT 1149
Query: 91 NSFGMICCSASVEV 104
N G S + V
Sbjct: 1150 NKTGQNSFSLELSV 1163
Score = 38.1 bits (87), Expect = 0.095
Identities = 48/213 (22%), Positives = 81/213 (38%), Gaps = 27/213 (12%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYE-----FFENQY 68
F L + E V C + G P P+V WY+ G I+ S + E +
Sbjct: 437 FTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEE 496
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKHE 128
I L ++ D+ + +A N +G + A + V + ED + G H
Sbjct: 497 ICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGN----------EDLSNNGSLHS 546
Query: 129 TGTHEEERANQIDEKEHPYKEEESI-SPGTPR----SADSSPSKSNHSLSLQSLGNL--D 181
+ A + + P+ E S+ P P+ + + +S+ + L+ NL D
Sbjct: 547 ANSTTNLAAIE-PQPSPPHSEPPSVEQPPKPKLEGVLVNHNEPRSSSRIGLRVHFNLPED 605
Query: 182 ISVSSSENPLGVKGTRHTGEAYDPSNTEEIANG 214
S + + GV TR T P + +E NG
Sbjct: 606 DKGSEASSEAGVVTTRQT----RPDSFQERFNG 634
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 53.9 bits (128), Expect = 2e-06
Identities = 38/151 (25%), Positives = 71/151 (47%), Gaps = 10/151 (6%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY-IHVL 72
FL+ L +Q+V + C+++GQP P V W+K+G+ ++ +Y E+Q H L
Sbjct: 5128 FLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEED---DHYMINEDQQGGHQL 5184
Query: 73 HLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRD--RGWKHETG 130
++ D VY+ A+NS G+ A + V+ +S + + + + + +
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244
Query: 131 THEEERANQIDEKEHPYKEEE----SISPGT 157
+E + DE + P EE ++PGT
Sbjct: 5245 REQEGTESTTDEGQLPQVVEELRDLQVAPGT 5275
Score = 47.4 bits (111), Expect = 2e-04
Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 5/104 (4%)
Query: 1 MKDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISN 60
M+ P PP T V E A L C ++G+PKPE W K+GQ +
Sbjct: 230 MRAEGAPASPPSTGTRTCT---VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVV 286
Query: 61 YEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
YE + + VL + C ++D +Y +A N G S V V
Sbjct: 287 YEDAQENF--VLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 46.2 bits (108), Expect = 3e-04
Identities = 39/161 (24%), Positives = 65/161 (40%), Gaps = 9/161 (5%)
Query: 8 QRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
Q PP F++ + + E DA C I G P P++ WYK+G + +
Sbjct: 6105 QVPPR-FVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSG 6163
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRGWKH 127
+ VL + +K D +Y+ N G SA E ++P L + R+ +
Sbjct: 6164 LL-VLVIRAASKEDLGLYECELVNRLG----SARASAELRIQSPMLQAQEQCHRE---QL 6215
Query: 128 ETGTHEEERANQIDEKEHPYKEEESISPGTPRSADSSPSKS 168
E+ ++ +K +E + +PR SPSKS
Sbjct: 6216 VAAVEVTEQETKVPKKTVIIEETITTVVKSPRGQRRSPSKS 6256
Score = 45.1 bits (105), Expect = 8e-04
Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
FL S +V E S+A RC + G P+P V+W K+G+ + G E L
Sbjct: 112 FLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRL-GEPDGPRVRVEELGEASALR 170
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSP 115
+ D Y++ A+N G +A++ V+ + + P
Sbjct: 171 IRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRP 212
Score = 38.5 bits (88), Expect = 0.072
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 21 QKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKN 80
Q P A + + G P P + W+K+GQ + S ++ + + +H L + T+
Sbjct: 5270 QVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTAS---AHIRMTDKKILHTLEIISVTRE 5326
Query: 81 DAAVYQISAKNSFGMICCSASVEVECSSENPQLSP 115
D+ Y N+ G SA + V + P+ P
Sbjct: 5327 DSGQYAAYISNAMGAAYSSARLLVR-GPDEPEEKP 5360
Score = 37.4 bits (85), Expect = 0.16
Identities = 20/89 (22%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 28 DAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQI 87
DA L C I G P P+V+W K+ Q + + + ++ ++ L + D+ Y
Sbjct: 26 DATLSCQIVGNPTPQVSWEKDQQPVAAG---ARFRLAQDGDLYRLTILDLALGDSGQYVC 82
Query: 88 SAKNSFGMICCSASVEVECSSENPQLSPN 116
A+N+ G + ++V+ + + +P+
Sbjct: 83 RARNAIGEAFAAVGLQVDAEAACAEQAPH 111
Score = 34.3 bits (77), Expect = 1.4
Identities = 11/22 (50%), Positives = 18/22 (81%)
Query: 31 LRCIISGQPKPEVTWYKNGQAI 52
L C ++G PKP ++WYK+G+A+
Sbjct: 6033 LACRVTGTPKPVISWYKDGKAV 6054
Score = 32.7 bits (73), Expect = 4.0
Identities = 30/148 (20%), Positives = 63/148 (42%), Gaps = 14/148 (9%)
Query: 1749 RKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRA-PVLLKKIQAEMFPEHSGNVKLS 1807
R+++ LK + + + + + S + E R PV+ K ++ E G + L
Sbjct: 2610 RRHTLVLKSIQRADAGIVRASSLK--VSTSARLEVRVKPVVFLKALDDLSAEERGTLALQ 2667
Query: 1808 CQFAEIHEDSTICWTKDSKSIAQVQR-----SAGDNSTVSFAIVQASPKDQGLYYCCIKN 1862
C+ ++ ++ + W KD + + +AG V + SP+D GLY C + +
Sbjct: 2668 CEVSD--PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLV---VHDVSPEDAGLYTCHVGS 2722
Query: 1863 SYGKVTAE-FNLTAEVLKQLSSRQDTKG 1889
+ +L + K+L + + +G
Sbjct: 2723 EETRARVRVHDLHVGITKRLKTMEVLEG 2750
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 53.9 bits (128), Expect = 2e-06
Identities = 38/151 (25%), Positives = 71/151 (47%), Gaps = 10/151 (6%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY-IHVL 72
FL+ L +Q+V + C+++GQP P V W+K+G+ ++ +Y E+Q H L
Sbjct: 5128 FLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEED---DHYMINEDQQGGHQL 5184
Query: 73 HLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRD--RGWKHETG 130
++ D VY+ A+NS G+ A + V+ +S + + + + + +
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244
Query: 131 THEEERANQIDEKEHPYKEEE----SISPGT 157
+E + DE + P EE ++PGT
Sbjct: 5245 REQEGTESTTDEGQLPQVVEELRDLQVAPGT 5275
Score = 47.4 bits (111), Expect = 2e-04
Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 5/104 (4%)
Query: 1 MKDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISN 60
M+ P PP T V E A L C ++G+PKPE W K+GQ +
Sbjct: 230 MRAEGAPASPPSTGTRTCT---VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVV 286
Query: 61 YEFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
YE + + VL + C ++D +Y +A N G S V V
Sbjct: 287 YEDAQENF--VLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 45.1 bits (105), Expect = 8e-04
Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
FL S +V E S+A RC + G P+P V+W K+G+ + G E L
Sbjct: 112 FLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRL-GEPDGPRVRVEELGEASALR 170
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSP 115
+ D Y++ A+N G +A++ V+ + + P
Sbjct: 171 IRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRP 212
Score = 42.7 bits (99), Expect = 0.004
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Query: 29 AVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQIS 88
A II G P+P VTWYK+ + S +S + + + H++ DA VY
Sbjct: 6374 AQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVA---SKDAGVYTCL 6430
Query: 89 AKNSFGMICCSASVEVECSSENP 111
A+N+ G + C A + V P
Sbjct: 6431 AQNTGGQVLCKAELLVLGGDNEP 6453
Score = 41.2 bits (95), Expect = 0.011
Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Query: 8 QRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQ 67
Q PP F++ + + E DA C I G P P++ WYK+G + +
Sbjct: 6105 QVPPR-FVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSG 6163
Query: 68 YIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
+ VL + +K D +Y+ N G SA + ++
Sbjct: 6164 LL-VLVIRAASKEDLGLYECELVNRLGSARASAELRIQ 6200
Score = 39.7 bits (91), Expect = 0.033
Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 5/102 (4%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
FL L + V L C +S QP + TW K+G ++ S + +N +L
Sbjct: 7465 FLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKN--FQLLT 7522
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSP 115
+ D VY S N+ G + + + +E P SP
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVLR---KAERPSSSP 7561
Score = 38.5 bits (88), Expect = 0.072
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 21 QKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKN 80
Q P A + + G P P + W+K+GQ + S ++ + + +H L + T+
Sbjct: 5270 QVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTAS---AHIRMTDKKILHTLEIISVTRE 5326
Query: 81 DAAVYQISAKNSFGMICCSASVEVECSSENPQLSP 115
D+ Y N+ G SA + V + P+ P
Sbjct: 5327 DSGQYAAYISNAMGAAYSSARLLVR-GPDEPEEKP 5360
Score = 37.4 bits (85), Expect = 0.16
Identities = 20/89 (22%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 28 DAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQI 87
DA L C I G P P+V+W K+ Q + + + ++ ++ L + D+ Y
Sbjct: 26 DATLSCQIVGNPTPQVSWEKDQQPVAAG---ARFRLAQDGDLYRLTILDLALGDSGQYVC 82
Query: 88 SAKNSFGMICCSASVEVECSSENPQLSPN 116
A+N+ G + ++V+ + + +P+
Sbjct: 83 RARNAIGEAFAAVGLQVDAEAACAEQAPH 111
Score = 36.6 bits (83), Expect = 0.28
Identities = 51/195 (26%), Positives = 80/195 (41%), Gaps = 28/195 (14%)
Query: 1712 KRKPEAPGSGHLAEGVKKKILSRVAALRLKLEEKENIRKNSAFLKKMPKLETSLSHTEEK 1771
KRK +P + L A L L+ K ++ S LK P+ EK
Sbjct: 7386 KRKWSSPSRSLFHFPGRHLPLDEPAELGLRERVKASVEHISRILKGRPE-------GLEK 7438
Query: 1772 QDP--KKPSC--------KREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTICW 1821
+ P KKP K RAP L+++ E +V L+CQ + + W
Sbjct: 7439 EGPPRKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQ-SVTLACQVSA-QPAAQATW 7496
Query: 1822 TKDS---KSIAQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAEVL 1878
+KD +S ++V SA + I+ +D G+Y C + N+ G VT T VL
Sbjct: 7497 SKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVT-----TTGVL 7551
Query: 1879 KQLSSRQDTKGCEEI 1893
++ + R + C +I
Sbjct: 7552 RK-AERPSSSPCPDI 7565
Score = 34.3 bits (77), Expect = 1.4
Identities = 11/22 (50%), Positives = 18/22 (81%)
Query: 31 LRCIISGQPKPEVTWYKNGQAI 52
L C ++G PKP ++WYK+G+A+
Sbjct: 6033 LACRVTGTPKPVISWYKDGKAV 6054
Score = 32.7 bits (73), Expect = 4.0
Identities = 30/148 (20%), Positives = 63/148 (42%), Gaps = 14/148 (9%)
Query: 1749 RKNSAFLKKMPKLETSLSHTEEKQDPKKPSCKREGRA-PVLLKKIQAEMFPEHSGNVKLS 1807
R+++ LK + + + + + S + E R PV+ K ++ E G + L
Sbjct: 2610 RRHTLVLKSIQRADAGIVRASSLK--VSTSARLEVRVKPVVFLKALDDLSAEERGTLALQ 2667
Query: 1808 CQFAEIHEDSTICWTKDSKSIAQVQR-----SAGDNSTVSFAIVQASPKDQGLYYCCIKN 1862
C+ ++ ++ + W KD + + +AG V + SP+D GLY C + +
Sbjct: 2668 CEVSD--PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLV---VHDVSPEDAGLYTCHVGS 2722
Query: 1863 SYGKVTAE-FNLTAEVLKQLSSRQDTKG 1889
+ +L + K+L + + +G
Sbjct: 2723 EETRARVRVHDLHVGITKRLKTMEVLEG 2750
Score = 32.0 bits (71), Expect = 6.8
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 1807 SCQFAEIHEDS---TICWTKDSKSIAQVQRSAG--DNSTVSFAIVQASPKDQGLYYCCIK 1861
+ QF I E ++ W KDS + R + + +T S + + KD G+Y C +
Sbjct: 6373 TAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQ 6432
Query: 1862 NSYGKVTAEFNL 1873
N+ G+V + L
Sbjct: 6433 NTGGQVLCKAEL 6444
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 52.8 bits (125), Expect = 4e-06
Identities = 38/117 (32%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
Query: 5 EGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFF 64
E P P+ F L + V +D +L+CII+ P P+V+W+K+G A+ G +
Sbjct: 716 EEPLEAPV-FEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEG 774
Query: 65 ENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE-CSSENPQLSPNLEDD 120
E H L L DA Y +A N G C+AS+ V S +P SP D+
Sbjct: 775 ER---HTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDE 828
Score = 49.3 bits (116), Expect = 4e-05
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 5/99 (5%)
Query: 9 RPPLCFLSTLLSQKVP--EKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFEN 66
RP L L T L + V E A C ISG P P VTW G ++ S N ++
Sbjct: 1059 RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEES---ENLRLRQD 1115
Query: 67 QYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
+H LH++ D +Y +SA N+ G CSA + VE
Sbjct: 1116 GGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154
Score = 48.9 bits (115), Expect = 5e-05
Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 6/115 (5%)
Query: 2 KDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNY 61
+ S+ + P F +L+ Q V E D ++ + G+PKP V+W +N Q +
Sbjct: 859 RSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRP----DQR 914
Query: 62 EFFENQY--IHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLS 114
F E + L + + DA Y A N +G C A +EV E+ L+
Sbjct: 915 RFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLA 969
Score = 44.7 bits (104), Expect = 0.001
Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 10/91 (10%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
FL L + V SD LR ++SG P+P + W+++GQ + + L
Sbjct: 45 FLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPS----------CLW 94
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
L C DA VY A+N G C A + V
Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125
Score = 41.6 bits (96), Expect = 0.009
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
FL L +V +A+L C ++G P P ++W+ NG I S + + + +H L
Sbjct: 1190 FLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSS---DDRRMTQYRDVHRLV 1246
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
A VY+ N G C A + V
Sbjct: 1247 FPAVGPQHAGVYKSVIANKLGKAACYAHLYV 1277
Score = 40.4 bits (93), Expect = 0.019
Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S + +V A ++ G+P P++ WYK+ + S +S + + EN+ V+
Sbjct: 1487 FESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVS-FVYEENECSLVV- 1544
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNLEDDRDRG 124
LS + D VY +A+N G + C A + V + ++ ED+ RG
Sbjct: 1545 LSTGAQ-DGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDEDHRG 1594
Score = 34.3 bits (77), Expect = 1.4
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIH 70
P F L Q + E A L C+ + P P ++W K+ +++ + + +
Sbjct: 2583 PPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGR--Q 2640
Query: 71 VLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+L + K A +Y+ SA N G I S +V V
Sbjct: 2641 LLSIPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 50.4 bits (119), Expect = 2e-05
Identities = 79/382 (20%), Positives = 141/382 (36%), Gaps = 46/382 (12%)
Query: 421 GPSSPQTGMTLILGPHQDGTSSVTEQGRYKLPTAPEAAENDYPGIQGETRDSHQAREEFA 480
GP Q G LG +D ++ + E+A Q T +S + E
Sbjct: 122 GPKDRQEGGNSRLGSDEDSDDTIQ--------ASEESAPQGQDSAQDTTSESRELDNEDR 173
Query: 481 SDNLLNMDESVRETEMK--LLSGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVR 538
D+ +S +E+E + + G S+ D+ + D S R R ++R+
Sbjct: 174 VDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMN 233
Query: 539 QPGMKGNPKKPN---ANLRESTTEGTLHLCSAKESAEPPLTQSDKRE------------- 582
GMK N AN ++S L S K + +++ D R
Sbjct: 234 SAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKS 293
Query: 583 --TSHTTAAATG-----RSSHADARECAISTQAEQEAKTLQTSTDSVSKEGNTNCKGEGM 635
T ++ + TG R S D++E + +++E++ + + S+E N + +
Sbjct: 294 DSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS 353
Query: 636 QVNTLFETSQVPDWSDPPQVQVQE-----TVRETISCSQMPAFSEPAGEESPFTGTTTIS 690
+ + D DP V++ + E S + + SE E++ + +++
Sbjct: 354 ESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLN 413
Query: 691 FSNLG--GVHKENAS----LAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLK--YEQS 742
FS EN+S L HS H E+ D D +ED +S
Sbjct: 414 FSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKS 473
Query: 743 ISEANDETMSPGVFSRHLPKDA 764
SE + + + + SR L DA
Sbjct: 474 SSEEDGQLKNIEIESRKLTVDA 495
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 50.4 bits (119), Expect = 2e-05
Identities = 79/382 (20%), Positives = 141/382 (36%), Gaps = 46/382 (12%)
Query: 421 GPSSPQTGMTLILGPHQDGTSSVTEQGRYKLPTAPEAAENDYPGIQGETRDSHQAREEFA 480
GP Q G LG +D ++ + E+A Q T +S + E
Sbjct: 106 GPKDRQEGGNSRLGSDEDSDDTIQ--------ASEESAPQGQDSAQDTTSESRELDNEDR 157
Query: 481 SDNLLNMDESVRETEMK--LLSGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVR 538
D+ +S +E+E + + G S+ D+ + D S R R ++R+
Sbjct: 158 VDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMN 217
Query: 539 QPGMKGNPKKPN---ANLRESTTEGTLHLCSAKESAEPPLTQSDKRE------------- 582
GMK N AN ++S L S K + +++ D R
Sbjct: 218 SAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKS 277
Query: 583 --TSHTTAAATG-----RSSHADARECAISTQAEQEAKTLQTSTDSVSKEGNTNCKGEGM 635
T ++ + TG R S D++E + +++E++ + + S+E N + +
Sbjct: 278 DSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS 337
Query: 636 QVNTLFETSQVPDWSDPPQVQVQE-----TVRETISCSQMPAFSEPAGEESPFTGTTTIS 690
+ + D DP V++ + E S + + SE E++ + +++
Sbjct: 338 ESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLN 397
Query: 691 FSNLG--GVHKENAS----LAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLK--YEQS 742
FS EN+S L HS H E+ D D +ED +S
Sbjct: 398 FSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKS 457
Query: 743 ISEANDETMSPGVFSRHLPKDA 764
SE + + + + SR L DA
Sbjct: 458 SSEEDGQLKNIEIESRKLTVDA 479
>gi|9558749 elongation factor-2 kinase [Homo sapiens]
Length = 725
Score = 50.1 bits (118), Expect = 2e-05
Identities = 56/245 (22%), Positives = 104/245 (42%), Gaps = 21/245 (8%)
Query: 1925 FGEGVHRKAFRSTVMHGLMPVFKPGHACVLKVHNAIAYGTRNNDELIQRNYKLAAQECYV 1984
FG G R+ FR+ + + HA K A Y + E + R+ ++ +
Sbjct: 138 FGRGAMRECFRTKKLSNFL------HAQQWK--GASNYVAKRYIEPVDRDVYF--EDVRL 187
Query: 1985 QNTARYYAKIYAAEAQPLEGFGEVPEIIPIFLIHRPENNIPYATVEEELIGEFVKYSIRD 2044
Q A+ + + Y P + ++ ++ I L RP P +E + G+++KY+
Sbjct: 188 QMEAKLWGEEYNRHKPPKQV--DIMQMCIIELKDRPGK--PLFHLEHYIEGKYIKYNSNS 243
Query: 2045 GKEINFLRRESEAGQKCCTFQHWVYQKTSGCLLVTDMQGVGMKLTDVGIATLAKGYKGFK 2104
G R+ F H+ ++++ L+V D+QGVG TD I T G
Sbjct: 244 G-----FVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHT-ETGTDFGD 297
Query: 2105 GNCSMTFIDQFKALHQCNKYCKMLGLKSLQNNNQKQKQPSIGKSKVQTNSMTIKKAGPET 2164
GN + + F H CN+ C+ +GL + + +++ +K+ ++ TI + E
Sbjct: 298 GNLGVRGMALFFYSHACNRICESMGLAPF-DLSPRERDAVNQNTKLLQSAKTILRGTEEK 356
Query: 2165 PGEKK 2169
G +
Sbjct: 357 CGSPR 361
>gi|155969693 myomesin family, member 3 [Homo sapiens]
Length = 1437
Score = 49.7 bits (117), Expect = 3e-05
Identities = 30/92 (32%), Positives = 39/92 (42%), Gaps = 1/92 (1%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGI-ISNYEFFENQYIHVL 72
F L S V E + +L C + P P+VTWYKN ID Y N + L
Sbjct: 156 FWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSL 215
Query: 73 HLSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+ C D+A Y + KN+ G A V V
Sbjct: 216 EIRRCAIEDSATYTVRVKNAHGQASSFAKVLV 247
Score = 39.3 bits (90), Expect = 0.042
Identities = 21/90 (23%), Positives = 36/90 (40%), Gaps = 3/90 (3%)
Query: 23 VPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDA 82
+ E L CI+SG P PE++W KN Q + + Y + + D+
Sbjct: 1346 IMEDKTLCLTCIVSGDPTPEISWLKNDQPVT---FLDRYRMEVRGTEVTITIEKVNSEDS 1402
Query: 83 AVYQISAKNSFGMICCSASVEVECSSENPQ 112
Y + KN +G ++ V + P+
Sbjct: 1403 GRYGVFVKNKYGSETGQVTISVFKHGDEPK 1432
>gi|93102361 palladin [Homo sapiens]
Length = 1106
Score = 49.3 bits (116), Expect = 4e-05
Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 2/99 (2%)
Query: 9 RPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQY 68
+PP+ F+ L + V + L C + G P P++ W K +++ S + + Y
Sbjct: 1008 KPPV-FIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGY 1066
Query: 69 IHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVECS 107
I +L + TK DA Y +SAKN G++ C+A ++V S
Sbjct: 1067 ICLL-IQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 1104
Score = 46.2 bits (108), Expect = 3e-04
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 2/104 (1%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F+ L SQ+V E S L C ++G P P V W+ G+ + + I + E +H L
Sbjct: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIH--CEGGDLHTLI 330
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSENPQLSPNL 117
++ ++D Y A N G SA V +E +S S +L
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL 374
Score = 42.7 bits (99), Expect = 0.004
Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 11/118 (9%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHV-- 71
F L K+ E C ++G PKP++ W+K+G+ I S++ +
Sbjct: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPK---SDHYTIQRDLDGTCS 835
Query: 72 LHLSCCTKNDAAVYQISAKNSFGMICCSASVEVEC------SSENPQLSPNLEDDRDR 123
LH + T +D Y I A N G I C+ + V+ S +P P++ R R
Sbjct: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR 893
Score = 37.4 bits (85), Expect = 0.16
Identities = 30/118 (25%), Positives = 48/118 (40%), Gaps = 6/118 (5%)
Query: 11 PLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYE-----FFE 65
P F L + V E VL C + G P +V W++ G I S + E
Sbjct: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
Query: 66 NQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEV-ECSSENPQLSPNLEDDRD 122
+ I L ++ DA ++ SA+N +G +A + V ++EN E + D
Sbjct: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNND 557
Score = 31.6 bits (70), Expect = 8.9
Identities = 16/62 (25%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 33 CIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNS 92
C +SG P P+++W +G+ + ++ +H L + T DA +Y A N
Sbjct: 932 CKVSGLPTPDLSWQLDGKPVRPDS--AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR 989
Query: 93 FG 94
G
Sbjct: 990 AG 991
>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
Length = 1794
Score = 48.9 bits (115), Expect = 5e-05
Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 6/91 (6%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S L V E D VL+C + G P P +TW NGQ I + E LH
Sbjct: 447 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE------LH 500
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+ D Y A+N+ G + CSA V V
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Score = 46.2 bits (108), Expect = 3e-04
Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F T+ +V E S A C I G P PEV W+K+ Q+I S ++ E+ ++
Sbjct: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF-QIDYDEDGNCSLII 1749
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
C +DA Y A NS G C+A + VE E
Sbjct: 1750 SDVCGDDDAK-YTCKAVNSLGEATCTAELIVETMEE 1784
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 19/130 (14%)
Query: 1764 SLSHTEEKQDPKKP-SCKR--------------EGRAPVLLKKIQAEMFPEHSGNVKLSC 1808
S S E K+D K +CKR +G AP +K+Q ++ + L C
Sbjct: 992 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLLLQC 1050
Query: 1809 QFAEIHEDSTICWTKDSKSIAQVQRS--AGDNSTVSFAIVQASPKDQGLYYCCIKNSYGK 1866
Q + +TI WT + K++ + + + S S +I +A P+D+GLY C KN G+
Sbjct: 1051 QVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1109
Query: 1867 VTAEFNLTAE 1876
+T +
Sbjct: 1110 AECSCQVTVD 1119
Score = 42.0 bits (97), Expect = 0.007
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 4/100 (4%)
Query: 7 PQRPPL-CFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFE 65
P +P FL L KV + S + +SG P PEV W NG I S ++ F +
Sbjct: 548 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES---EDFHFEQ 604
Query: 66 NQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
H L + D Y A NS G + A + V+
Sbjct: 605 RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
Score = 41.2 bits (95), Expect = 0.011
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F+S S ++ C I+G P P V W ++G+A+ ++E +N+ + L
Sbjct: 654 FISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKD--TGHFEVLQNEDVFTLV 711
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSS 108
L A Y+I KN G C S+ ++ SS
Sbjct: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSS 746
Score = 40.8 bits (94), Expect = 0.015
Identities = 36/144 (25%), Positives = 57/144 (39%), Gaps = 10/144 (6%)
Query: 33 CIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNS 92
C I+G+P+P+VTW K + S +S E + VL + ++D VY N
Sbjct: 182 CKITGRPQPQVTWLKGNVPLQPSARVS---VSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
Query: 93 FGMICCSASVEVE-CSSENPQLSPNLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEE 151
G SA + ++ S N + K T +E +++D E K +
Sbjct: 239 SGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE--SKLDSLEAAAKSKN 296
Query: 152 SISP----GTPRSADSSPSKSNHS 171
SP P +A+S P S
Sbjct: 297 CSSPQRGGSPPWAANSQPQPPRES 320
Score = 35.0 bits (79), Expect = 0.80
Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 7/124 (5%)
Query: 2 KDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNY 61
K SE P F L V E +L+C +S P + W NG+ + + I
Sbjct: 1020 KRSESQGTAP-AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-- 1076
Query: 62 EFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE--CSSENPQLSPNLED 119
+ + + + D +Y+ AKN G CS V V+ +SEN + +P ++
Sbjct: 1077 -LSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK-APEMKS 1134
Query: 120 DRDR 123
R +
Sbjct: 1135 RRPK 1138
Score = 34.3 bits (77), Expect = 1.4
Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 23 VPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSG---IISNYEFFENQYIHVLHLSCCTK 79
+ E + A + G P+P+VTW++NGQ I G + + IH +H +
Sbjct: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH-----E 98
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECS 107
D Y A N G + + VE S
Sbjct: 99 EDRGKYTCEATNGSGARQVTVELTVEGS 126
Score = 32.0 bits (71), Expect = 6.8
Identities = 59/249 (23%), Positives = 98/249 (39%), Gaps = 57/249 (22%)
Query: 1670 QDPCQKGTLGCAKKSREREKSLEARAGKSPGTLTAVTGSEEVKRKPEAPGSGHLA-EGVK 1728
Q P + C R ++ + S TL A V+ +P APG G L+ G +
Sbjct: 315 QPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA----RVQPEPRAPGLGVLSPSGEE 370
Query: 1729 KK---------------------ILSRVAALRLKLEEKENIRKNSAFLKKMPKLETSLSH 1767
+K ++S+ A R+ +E + ++SAF PK E S
Sbjct: 371 RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQ----RDSAF----PKFE-SKPQ 421
Query: 1768 TEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTIC------- 1820
++E ++ + + EG A + E+ P S +K C E + C
Sbjct: 422 SQEVKENQTVKFRCEGLAVM-------EVAPSFSSVLK-DCAVIEGQDFVLQCSVRGTPV 473
Query: 1821 ----WTKDSKSIAQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAE 1876
W + + I Q RS + I A P+D G Y C +N+ G+V+ +T
Sbjct: 474 PRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT-- 530
Query: 1877 VLKQLSSRQ 1885
V ++ SSR+
Sbjct: 531 VHEKKSSRK 539
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 48.9 bits (115), Expect = 5e-05
Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 6/91 (6%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F S L V E D VL+C + G P P +TW NGQ I + E LH
Sbjct: 447 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE------LH 500
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEV 104
+ D Y A+N+ G + CSA V V
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Score = 46.2 bits (108), Expect = 3e-04
Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F T+ +V E S A C I G P PEV W+K+ Q+I S ++ E+ ++
Sbjct: 1742 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF-QIDYDEDGNCSLII 1800
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSSE 109
C +DA Y A NS G C+A + VE E
Sbjct: 1801 SDVCGDDDAK-YTCKAVNSLGEATCTAELIVETMEE 1835
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 19/130 (14%)
Query: 1764 SLSHTEEKQDPKKP-SCKR--------------EGRAPVLLKKIQAEMFPEHSGNVKLSC 1808
S S E K+D K +CKR +G AP +K+Q ++ + L C
Sbjct: 992 SASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ-DVHVAEGKKLLLQC 1050
Query: 1809 QFAEIHEDSTICWTKDSKSIAQVQRS--AGDNSTVSFAIVQASPKDQGLYYCCIKNSYGK 1866
Q + +TI WT + K++ + + + S S +I +A P+D+GLY C KN G+
Sbjct: 1051 QVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1109
Query: 1867 VTAEFNLTAE 1876
+T +
Sbjct: 1110 AECSCQVTVD 1119
Score = 42.0 bits (97), Expect = 0.007
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 4/100 (4%)
Query: 7 PQRPPL-CFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFE 65
P +P FL L KV + S + +SG P PEV W NG I S ++ F +
Sbjct: 548 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES---EDFHFEQ 604
Query: 66 NQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE 105
H L + D Y A NS G + A + V+
Sbjct: 605 RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
Score = 41.2 bits (95), Expect = 0.011
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 14 FLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLH 73
F+S S ++ C I+G P P V W ++G+A+ ++E +N+ + L
Sbjct: 654 FISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKD--TGHFEVLQNEDVFTLV 711
Query: 74 LSCCTKNDAAVYQISAKNSFGMICCSASVEVECSS 108
L A Y+I KN G C S+ ++ SS
Sbjct: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSS 746
Score = 40.8 bits (94), Expect = 0.015
Identities = 36/144 (25%), Positives = 57/144 (39%), Gaps = 10/144 (6%)
Query: 33 CIISGQPKPEVTWYKNGQAIDGSGIISNYEFFENQYIHVLHLSCCTKNDAAVYQISAKNS 92
C I+G+P+P+VTW K + S +S E + VL + ++D VY N
Sbjct: 182 CKITGRPQPQVTWLKGNVPLQPSARVS---VSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
Query: 93 FGMICCSASVEVE-CSSENPQLSPNLEDDRDRGWKHETGTHEEERANQIDEKEHPYKEEE 151
G SA + ++ S N + K T +E +++D E K +
Sbjct: 239 SGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE--SKLDSLEAAAKSKN 296
Query: 152 SISP----GTPRSADSSPSKSNHS 171
SP P +A+S P S
Sbjct: 297 CSSPQRGGSPPWAANSQPQPPRES 320
Score = 35.0 bits (79), Expect = 0.80
Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 7/124 (5%)
Query: 2 KDSEGPQRPPLCFLSTLLSQKVPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSGIISNY 61
K SE P F L V E +L+C +S P + W NG+ + + I
Sbjct: 1020 KRSESQGTAP-AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-- 1076
Query: 62 EFFENQYIHVLHLSCCTKNDAAVYQISAKNSFGMICCSASVEVE--CSSENPQLSPNLED 119
+ + + + D +Y+ AKN G CS V V+ +SEN + +P ++
Sbjct: 1077 -LSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK-APEMKS 1134
Query: 120 DRDR 123
R +
Sbjct: 1135 RRPK 1138
Score = 34.3 bits (77), Expect = 1.4
Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 23 VPEKSDAVLRCIISGQPKPEVTWYKNGQAIDGSG---IISNYEFFENQYIHVLHLSCCTK 79
+ E + A + G P+P+VTW++NGQ I G + + IH +H +
Sbjct: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH-----E 98
Query: 80 NDAAVYQISAKNSFGMICCSASVEVECS 107
D Y A N G + + VE S
Sbjct: 99 EDRGKYTCEATNGSGARQVTVELTVEGS 126
Score = 32.0 bits (71), Expect = 6.8
Identities = 59/249 (23%), Positives = 98/249 (39%), Gaps = 57/249 (22%)
Query: 1670 QDPCQKGTLGCAKKSREREKSLEARAGKSPGTLTAVTGSEEVKRKPEAPGSGHLA-EGVK 1728
Q P + C R ++ + S TL A V+ +P APG G L+ G +
Sbjct: 315 QPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA----RVQPEPRAPGLGVLSPSGEE 370
Query: 1729 KK---------------------ILSRVAALRLKLEEKENIRKNSAFLKKMPKLETSLSH 1767
+K ++S+ A R+ +E + ++SAF PK E S
Sbjct: 371 RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQ----RDSAF----PKFE-SKPQ 421
Query: 1768 TEEKQDPKKPSCKREGRAPVLLKKIQAEMFPEHSGNVKLSCQFAEIHEDSTIC------- 1820
++E ++ + + EG A + E+ P S +K C E + C
Sbjct: 422 SQEVKENQTVKFRCEGLAVM-------EVAPSFSSVLK-DCAVIEGQDFVLQCSVRGTPV 473
Query: 1821 ----WTKDSKSIAQVQRSAGDNSTVSFAIVQASPKDQGLYYCCIKNSYGKVTAEFNLTAE 1876
W + + I Q RS + I A P+D G Y C +N+ G+V+ +T
Sbjct: 474 PRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT-- 530
Query: 1877 VLKQLSSRQ 1885
V ++ SSR+
Sbjct: 531 VHEKKSSRK 539
>gi|44681484 cell division cycle associated 2 [Homo sapiens]
Length = 1023
Score = 48.5 bits (114), Expect = 7e-05
Identities = 106/510 (20%), Positives = 182/510 (35%), Gaps = 61/510 (11%)
Query: 743 ISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENVCDEPRDREAVC 802
+ + + + +SP F+ + DA D R P + PT L +V +P + +
Sbjct: 282 VGKGSSDAVSPDTFTAEVSSDAVPDVRSPATPACRRDLPTPKTFVLRSVLKKPSVKMCLE 341
Query: 803 AME--CFEA-GDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAEGQNKVSDLCSSNDKT 859
+++ C D GT I +L +K + E + + K + D +
Sbjct: 342 SLQEHCNNLYDDDGTHPSLISNLPNCCKEKEAEDEE-NFEAPAFLNMRKRKRVTFGEDLS 400
Query: 860 LEVFFQTQVSETSV---STCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVEN 916
EVF ++ + T + T KD + + S L + GENL +E
Sbjct: 401 PEVFDESLPANTPLRKGGTPVCKKDFSGLSSLLLEQSPVPEPLPQPDFDDKGENLENIE- 459
Query: 917 STYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPA 976
PL + S S L T SS NN +K SP T T
Sbjct: 460 ---PLQVSFAVLSSPNKSSISETLSGTDTFSSSNN--------HEKISSPKVGRITRTSN 508
Query: 977 SYSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIATEVHPAKYLAVSIPEDKHAGGT 1036
+ +VS E++ + TEV P K ++ + + T
Sbjct: 509 RRNQLVSV--------------------VEESVCNLLNTEVQPCKEKKINRRKSQETKCT 548
Query: 1037 EERFPRAS------HEKVSQFPSQVQLDHILSGATIKSTKELLCRAPSVPGVPHHVLQLP 1090
+ P+ S +K + VQ + I S K LL P +P VP +P
Sbjct: 549 KRALPKKSQVLKSCRKKKGKGKKSVQ-KSLYGERDIASKKPLLSPIPELPEVPEMTPSIP 607
Query: 1091 E----GEGFCSNSPLQVDNLSGDKSQTVDRADFRSYEENFQERGSETKQGVQQ--QSLSQ 1144
G G+ S++ +++ + K+ V R D ++ + K V + +
Sbjct: 608 SIRRLGSGYFSSNG-KLEEVKTPKN-PVKRKDLLRHDPDLHMHQGYDKYDVSEFCSYIKS 665
Query: 1145 QGSLSAPDFQQSLPTTSAAQEERNLVPTAHSPASSREGAGQRSGWGTRVSVVAETAGEED 1204
SL + T E +P A + + S ++G + VS + T EE
Sbjct: 666 SSSLGNATSDEDPNTNIMNINENKNIPKAKNKSESEN--EPKAGTDSPVSCASVT--EER 721
Query: 1205 SQALSNVPSLSDILLEESKEYRPGNWEAGN 1234
+ S P+L+ L++ +E+ G A N
Sbjct: 722 VASDSPKPALT---LQQGQEFSAGGQNAEN 748
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 48.1 bits (113), Expect = 9e-05
Identities = 112/520 (21%), Positives = 183/520 (35%), Gaps = 51/520 (9%)
Query: 556 STTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRS-----SHADARECAISTQAEQ 610
++TEG+ + AE T +D E S TTAA+T S S AD+ ST A+
Sbjct: 556 TSTEGSEMTTVSTTGAE---TTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST-ADS 611
Query: 611 EAKTL-----QTSTDSVSKEGNTNCKGEGMQVNTLF----ETSQVPDWSDPPQV---QVQ 658
E + +T+T S + T EG + T+ ET+ V + +
Sbjct: 612 ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGS 671
Query: 659 ETVRETISCSQMPAFSEPAGEES-PFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGP 717
ET + + S+ +E +G + TG+ T S G + + + SE+ +
Sbjct: 672 ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGS--ETTTTSTEGSEITTASITG 729
Query: 718 QHEEKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVA 777
+G+ + S S ET + S + +A ++
Sbjct: 730 SETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG 789
Query: 778 SPEP-TDTALTLENVCDEPRDREAVCAMECFEAGDQGTC-FDTID-SLVGRPVDKYSPQE 834
S TA + + + E T +TI S G + E
Sbjct: 790 SETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTE 849
Query: 835 ICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTF 894
T EG + S++ T T SET+ ++ + S+ + T+T
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTAT---TIGSETTTASTEGSETTTTSTEGSETTTA 906
Query: 895 TLNISHTASEGATGE--NLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNP 952
+ S + TG A E S AST G E + S +G ET +S+E +
Sbjct: 907 STEGSEITTVSTTGSETTTASTEGSETTTAST--EGSELTTVSTTG--SETITVSAEGSE 962
Query: 953 LVQFKEGGDKSPSPSAA----DTTATPASYSSIVSFPWEKPTTL-----------TANNE 997
G ++ + S A T +T S ++ S + TT+ T E
Sbjct: 963 TTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022
Query: 998 CFQATRETEDTSTVTIATEVHPAKYLAVSIPEDKHAGGTE 1037
+ E +T+TVT A A Y S G+E
Sbjct: 1023 TTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSE 1062
Score = 46.2 bits (108), Expect = 3e-04
Identities = 96/478 (20%), Positives = 157/478 (32%), Gaps = 59/478 (12%)
Query: 555 ESTTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATG-RSSHADARECAISTQAEQEAK 613
E+TT T H + S T S TT + G ++ A + +T +++K
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272
Query: 614 TLQTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAF 673
T ST + E +T+ + + P +V E + A
Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV--FAAG 330
Query: 674 SEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNF 733
SE + + TTT+S + G AS+ T G +
Sbjct: 331 SETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDSTTGSE--------------- 372
Query: 734 REDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALT---LEN 790
+ S ET + A + E VS E T ++T
Sbjct: 373 ------TTTASTEGSETTT-----------ASTEGSEATTVSTTGSETTTVSITDSETTT 415
Query: 791 VCDEPRDREAVCA--MECFEAGDQG---TCFDTIDS-LVGRPVDKYSPQEICSVDTELAE 844
C E + AV E A +G T T DS + + + +E
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475
Query: 845 GQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASE 904
S+ ++++ LE T V T +S +G+ + T + +S SE
Sbjct: 476 AYTTGSETTTASNTGLET---TTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532
Query: 905 GAT----GENLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGG 960
T G V + +T G E + S +G ET S+E + G
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGA--ETTTDSTEGSGTTAASTAG 590
Query: 961 DKSPSPSAAD---TTATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIAT 1015
++ + S AD TTA+ A + + TT + T TE + T T++T
Sbjct: 591 SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648
Score = 46.2 bits (108), Expect = 3e-04
Identities = 94/468 (20%), Positives = 165/468 (35%), Gaps = 34/468 (7%)
Query: 556 STTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQEAKTL 615
STT+ + S S E +T ++ ET TT +ATG + +T + ++T
Sbjct: 647 STTDSETTMVSTTGS-ERTITSTEGSET--TTVSATGSETTVSTEGSGTTTVSITGSETT 703
Query: 616 QTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSE 675
+ ST T EG ++ T T + + ET + S+ + S
Sbjct: 704 KVSTTGSE---TTTTSTEGSEITTASITGSE---TTTASTEGSETTTASTEGSETTSAST 757
Query: 676 PAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFRE 735
E + T +TT S + + + ++A T G + + + F E
Sbjct: 758 TGSETT--TASTTSSETTMASIMGSETTMAS-------TIGSETTKVSTASSKMTTVFTE 808
Query: 736 DLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENVCDEP 795
+ + + + A++ T S +P + S T + E
Sbjct: 809 NSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 796 RDREAVCAM----ECFEAGDQGTCFDTIDSLVGRPVDKYSPQ--EICSVDTELAEGQNKV 849
E A E A +G+ T S G S + EI +V T +E
Sbjct: 869 ESSETTTATTIGSETTTASTEGS-ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 850 SDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGE 909
++ + + E T VS T T S +G+ T+T T S T + G
Sbjct: 928 TEGSETTTASTEGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGS 981
Query: 910 NLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSA- 968
V + + G E + S++G + T + ++ + EG + + +A
Sbjct: 982 ETTTVSTAGSETTTASIEGSETTTVSSTGS-ETTTVSTTGTETTITSTEGSETTTVTTAG 1040
Query: 969 ADTTATPASYSSIVSFPWE-KPTTLTANNECFQATRETEDTSTVTIAT 1015
++TTA + S + E TT + T T D T T++T
Sbjct: 1041 SETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088
Score = 45.8 bits (107), Expect = 5e-04
Identities = 138/645 (21%), Positives = 208/645 (32%), Gaps = 73/645 (11%)
Query: 576 TQSDKRETSHTTAAATGRS----SHADARECAISTQAEQEAKTLQTSTDSVSKEGNTNCK 631
T + E S T A+T S + + E T A E KT T+ + NT
Sbjct: 433 TTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT--- 489
Query: 632 GEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPF--TGTTTI 689
G++ T+F + + + ET + + S+M S E + TG+ T
Sbjct: 490 --GLETTTVFT---IGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT 544
Query: 690 SFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDE 749
+ S G + + + SE+ + +G+ + S A E
Sbjct: 545 TVSTTG--LETTTTSTEGSEMTTVSTTGAETTTDSTEGS----------GTTAASTAGSE 592
Query: 750 TMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENVCDEPRDREAVCAMECFEA 809
T + + AD E + S E T + T +
Sbjct: 593 TTTVSTADSENTTASTAD-SETTSASTTGSETTTASTTSSETTTASTE------------ 639
Query: 810 GDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVS 869
G + T T DS S + I S TE +E VS S + E T VS
Sbjct: 640 GSETTTVSTTDSETTMVSTTGSERTITS--TEGSE-TTTVSATGSETTVSTEGSGTTTVS 696
Query: 870 ETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVHAGQ 929
T T K S G+ + + S T SE T A E S AST G
Sbjct: 697 ITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT----ASTEGSETTTAST--EGS 750
Query: 930 EQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKP 989
E S S +G T +S + S ++TT + S +
Sbjct: 751 ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT------- 803
Query: 990 TTLTANNECFQATRETEDTSTV-TIATEVHPAKYLAVSIPEDKHAGGTEERFPRASHEKV 1048
T T N+E A+ +T+TV T +E PA G+E AS E
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET--TTASTEGS 861
Query: 1049 SQFPSQVQLDHILSGATIKSTKELLCRAPSVPGVPHHVLQLPEGE-GFCSNSPLQVDNLS 1107
+ + + TI S S G E S ++ +S
Sbjct: 862 ETTTASTESSETTTATTIGSE----TTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917
Query: 1108 GDKSQTVDRADFRSYEENFQERGSE----TKQGVQQQSLSQQGS--LSAPDFQQSLPTTS 1161
S+T + S GSE + G + ++S +GS + T S
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977
Query: 1162 AAQEERNLVPTAHSPASSREGAGQR----SGWGTRVSVVAETAGE 1202
A E V TA S ++ G S G+ + V+ T E
Sbjct: 978 TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022
Score = 43.1 bits (100), Expect = 0.003
Identities = 131/663 (19%), Positives = 218/663 (32%), Gaps = 62/663 (9%)
Query: 379 SGMGCGSRVSGDAGPMVATAGFCGHHSQPQEVGVRSSRVSKHGPSSPQTGMTLILGPHQD 438
S G + AG TA G + G ++ VS G +T M +G
Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGT---ETTMVSAMGSETT 125
Query: 439 GTSSVTEQGRYKLPTAPEAAENDYPGIQ---GETRDSHQAREEFASDNLLNMDESVRETE 495
S+ + + E G + T DS + + + ET
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 496 MKLLSGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVRQPGMKGNPKKPNANLRE 555
+G + + ET G + + ++ G + +
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 556 STTEGTLHLCSAKESAEP--PLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQE-- 611
+T G+ ++ E +E T+ K T+ TT T +S + ST +
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305
Query: 612 AKTLQTSTDSVSKEGNTNCKGEGMQVNTLF----ETSQVPDWSDPPQVQVQETVRETISC 667
A T+ T VS + +V T+F ET + V T ET +
Sbjct: 306 ASTIGPETTKVSTASS--------EVTTVFAAGSETIRASTVGSETTT-VSTTGSETTTA 356
Query: 668 SQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDG 727
S M SE + + + + TTT S G AS T G + D
Sbjct: 357 SIMG--SETSTDSTTGSETTTASTE---GSETTTASTEGSEATTVSTTGSETTTVSITDS 411
Query: 728 NIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALT 787
E + ++S ET + + + +D A + S T T
Sbjct: 412 ETTTTCTEGSEMT-AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470
Query: 788 LENVCDEPRDREAVCAMEC-------FEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDT 840
E E A F G T T S + E+ +V T
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET--TAVSATGSEMTTVST 528
Query: 841 ELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISH 900
E +E + + ++ +T T VS T + T +S +G S M+ + T+
Sbjct: 529 EGSEN----TTVSTTGSET------TTVSTTGLETTTTSTEG-SEMTTVSTTGAETTTDS 577
Query: 901 TASEGATGENLAKVENSTYPLASTVH-----AGQEQPSPSNSGGLDETQLLSSENNPLVQ 955
T G T + A E +T A + + A E S S +G ET S+ ++
Sbjct: 578 TEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGS--ETTTASTTSSETTT 635
Query: 956 FKEGGDKSPSPSAADT----TATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTV 1011
G ++ + S D+ +T S +I S + TT++A + T TE + T
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS--ETTVSTEGSGTT 693
Query: 1012 TIA 1014
T++
Sbjct: 694 TVS 696
Score = 38.5 bits (88), Expect = 0.072
Identities = 47/156 (30%), Positives = 69/156 (44%), Gaps = 20/156 (12%)
Query: 866 TQVSETSV-STCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLAST 924
T SET+V ST S S + T+ +T + S T + TG + V
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTAD-SETTAASTTGSEMTTVFT-------- 179
Query: 925 VHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAA--DTTA--TPASYSS 980
AG E +PS +G ET +S+ + G ++ + S A +TTA T S ++
Sbjct: 180 --AGSETITPSTAG--SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235
Query: 981 IVSFPWEKPTTLTANNECFQATRETEDTSTVTIATE 1016
VS + T TA +E A+ TED+ T T TE
Sbjct: 236 KVSTAGSETTVSTAGSETTAAS--TEDSETNTAFTE 269
Score = 38.5 bits (88), Expect = 0.072
Identities = 115/616 (18%), Positives = 207/616 (33%), Gaps = 55/616 (8%)
Query: 440 TSSVTEQGRYKLPTAPEAAENDYPGIQGETRDSHQAREEFASDNLLNMDESVRETEMKLL 499
T+ V+ G T+ E +E I G ++ A E + + + S ET
Sbjct: 702 TTKVSTTGSETTTTSTEGSEITTASITGS--ETTTASTEGSETTTASTEGS--ETTSAST 757
Query: 500 SGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVRQPGMKGNP---KKPNANLRES 556
+G + + ET +G + + ++ +V K + + +
Sbjct: 758 TGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817
Query: 557 TTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQE---AK 613
T T + +A P T + T+ +T + ++ + E ++ E A
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877
Query: 614 TLQTSTDSVSKEGN--TNCKGEGMQVNTLF-ETSQVPDWSDPPQVQVQETVRETISCSQM 670
T+ + T + S EG+ T EG + T E S++ V T ET + S
Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEI--------TTVSTTGSETTTASTE 929
Query: 671 PAFSEPAGEESP------FTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQD 724
+ + A E TG+ TI+ S G + SE +
Sbjct: 930 GSETTTASTEGSELTTVSTTGSETITVSAEGS--ETTTVTTMGSETTTASTAGSETTTVS 987
Query: 725 RDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDT 784
G+ + ++S ET + + + E V+ A E T
Sbjct: 988 TAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS-TEGSETTTVTTAGSETTAV 1046
Query: 785 ALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAE 844
T + + G + T T D ++ + S T +
Sbjct: 1047 YTTGSETTTTSTEGSETTTVST--TGSETTTASTAD------LETTTVSTSGSGTTTAST 1098
Query: 845 GQNKVSDLCSSNDKTLEVFFQ----TQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISH 900
++ + + + KT + T VS TS T +S G+ + + T + T +S
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVST 1158
Query: 901 TASEGATGE------NLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLV 954
SE T E S AST AG E + S +G + T ++ +
Sbjct: 1159 IGSEATTSSAAGSEATTTSTEGSETTTAST--AGSETTTASTAGS-ETTTASTAGSETTT 1215
Query: 955 QFKEGGDKSPSPSAADTTATPASYSSIVSFPW----EKPTTLTANNECFQATRETEDTST 1010
G + + + + T+TP+S S + + E TA+ E + +T+T
Sbjct: 1216 ASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTT 1275
Query: 1011 VTIATEVHPAKYLAVS 1026
V+I A VS
Sbjct: 1276 VSITASGATAASTTVS 1291
Score = 37.7 bits (86), Expect = 0.12
Identities = 84/460 (18%), Positives = 154/460 (33%), Gaps = 34/460 (7%)
Query: 575 LTQSDKRETSHTTAAATGRSSHADARECAISTQAEQE-AKTLQTSTDSVSKEGN--TNCK 631
+T S+ + S T + T S+ A T +E A T + T + S EG+ T+
Sbjct: 697 ITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSAS 756
Query: 632 GEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISF 691
G + T TS + + + T+ TI + + + FT + +
Sbjct: 757 TTGSETTTASTTSSETTMASI--MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTI 814
Query: 692 SNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETM 751
++ S A + T G + +G+ + + S + ET
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874
Query: 752 SPGVFSRHLPKDARADFREPVAVSVASPEPTDTA-----LTLENVCDEPRDREAVCAMEC 806
+ A + E S E T + +T + + E
Sbjct: 875 TATTIGSETTT-ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933
Query: 807 FEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAEGQNKVSDLCSSNDKTLEVFFQT 866
A +G+ T+ + + T AEG + ++ T T
Sbjct: 934 TTASTEGSELTTVSTTGSETI------------TVSAEGSETTTVTTMGSETTTA---ST 978
Query: 867 QVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVH 926
SET+ + S+ + + T+T + S T + TG +
Sbjct: 979 AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTT 1038
Query: 927 AGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAAD----TTATPASYSSIV 982
AG E + +G ET S+E + G ++ + S AD T +T S ++
Sbjct: 1039 AGSETTAVYTTG--SETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTA 1096
Query: 983 SFPWEKPTT--LTANNECFQATRETEDTSTVTIATEVHPA 1020
S + TT +T + +T +E T+ T ++E A
Sbjct: 1097 STAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTA 1136
Score = 35.0 bits (79), Expect = 0.80
Identities = 91/485 (18%), Positives = 152/485 (31%), Gaps = 82/485 (16%)
Query: 583 TSHTTAAATGRSSHADARECAISTQAEQEAKTLQTSTDSVSKEGNTNCKGEGMQVNTLFE 642
T+ TT++ T +S A + +ST + T+T + T G ++ T+F
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSE------TTTAYTADSETTAASTTGSEMTTVFT 179
Query: 643 TSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENA 702
ET+ + + S+ S AG E+ TT + H E
Sbjct: 180 AGS-------------ETITPSTAGSETTTVST-AGSETTTVSTTGSETTTASTAHSETT 225
Query: 703 SLAQH-----------SEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETM 751
+ + SE T G + D F ED K + + + T
Sbjct: 226 AASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA 285
Query: 752 SPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENV-----CDEPRDREAVCAMEC 806
+ S P A E S PE T + V R + E
Sbjct: 286 ASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343
Query: 807 FEAGDQGTCFDTI---------DSLVGRPVDKYSPQ--EICSVDTELAEG---------- 845
G+ T DS G S + E + TE +E
Sbjct: 344 TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403
Query: 846 ------QNKVSDLCSSNDKTLEVFF--------QTQVSETSVSTCKSSKDGNSVMSPLFT 891
++ + C+ + V T+ SE ++++ S+ + T
Sbjct: 404 TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSET 463
Query: 892 STFTLNISHTASEGATGENLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENN 951
+T T S T + TG N+ + G + + S G ET +S+ +
Sbjct: 464 TTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG--SETTAVSATGS 521
Query: 952 PLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTV 1011
+ G ++ + S + T S + + E TT T +E T T T
Sbjct: 522 EMTTVSTEGSENTTVSTTGSETTTVSTTGL-----ETTTTSTEGSE--MTTVSTTGAETT 574
Query: 1012 TIATE 1016
T +TE
Sbjct: 575 TDSTE 579
Score = 31.6 bits (70), Expect = 8.9
Identities = 32/154 (20%), Positives = 63/154 (40%), Gaps = 11/154 (7%)
Query: 869 SETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVHAG 928
S T+ ++ S+ ++ T+T + S T + TG V S + +T AG
Sbjct: 13 SNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAG 72
Query: 929 QEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEK 988
E + S++G T ++ + S + S T + + +++VS +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTV---------STAGSETTTVSITGTETTMVSAMGSE 123
Query: 989 PTT--LTANNECFQATRETEDTSTVTIATEVHPA 1020
TT T++ +T +E T+ T+ +E A
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTA 157
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 48.1 bits (113), Expect = 9e-05
Identities = 112/520 (21%), Positives = 183/520 (35%), Gaps = 51/520 (9%)
Query: 556 STTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRS-----SHADARECAISTQAEQ 610
++TEG+ + AE T +D E S TTAA+T S S AD+ ST A+
Sbjct: 556 TSTEGSEMTTVSTTGAE---TTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST-ADS 611
Query: 611 EAKTL-----QTSTDSVSKEGNTNCKGEGMQVNTLF----ETSQVPDWSDPPQV---QVQ 658
E + +T+T S + T EG + T+ ET+ V + +
Sbjct: 612 ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGS 671
Query: 659 ETVRETISCSQMPAFSEPAGEES-PFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGP 717
ET + + S+ +E +G + TG+ T S G + + + SE+ +
Sbjct: 672 ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGS--ETTTTSTEGSEITTASITG 729
Query: 718 QHEEKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVA 777
+G+ + S S ET + S + +A ++
Sbjct: 730 SETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG 789
Query: 778 SPEP-TDTALTLENVCDEPRDREAVCAMECFEAGDQGTC-FDTID-SLVGRPVDKYSPQE 834
S TA + + + E T +TI S G + E
Sbjct: 790 SETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTE 849
Query: 835 ICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTF 894
T EG + S++ T T SET+ ++ + S+ + T+T
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTAT---TIGSETTTASTEGSETTTTSTEGSETTTA 906
Query: 895 TLNISHTASEGATGE--NLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNP 952
+ S + TG A E S AST G E + S +G ET +S+E +
Sbjct: 907 STEGSEITTVSTTGSETTTASTEGSETTTAST--EGSELTTVSTTG--SETITVSAEGSE 962
Query: 953 LVQFKEGGDKSPSPSAA----DTTATPASYSSIVSFPWEKPTTL-----------TANNE 997
G ++ + S A T +T S ++ S + TT+ T E
Sbjct: 963 TTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022
Query: 998 CFQATRETEDTSTVTIATEVHPAKYLAVSIPEDKHAGGTE 1037
+ E +T+TVT A A Y S G+E
Sbjct: 1023 TTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSE 1062
Score = 46.2 bits (108), Expect = 3e-04
Identities = 96/478 (20%), Positives = 157/478 (32%), Gaps = 59/478 (12%)
Query: 555 ESTTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATG-RSSHADARECAISTQAEQEAK 613
E+TT T H + S T S TT + G ++ A + +T +++K
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272
Query: 614 TLQTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAF 673
T ST + E +T+ + + P +V E + A
Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV--FAAG 330
Query: 674 SEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNF 733
SE + + TTT+S + G AS+ T G +
Sbjct: 331 SETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDSTTGSE--------------- 372
Query: 734 REDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALT---LEN 790
+ S ET + A + E VS E T ++T
Sbjct: 373 ------TTTASTEGSETTT-----------ASTEGSEATTVSTTGSETTTVSITDSETTT 415
Query: 791 VCDEPRDREAVCA--MECFEAGDQG---TCFDTIDS-LVGRPVDKYSPQEICSVDTELAE 844
C E + AV E A +G T T DS + + + +E
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475
Query: 845 GQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASE 904
S+ ++++ LE T V T +S +G+ + T + +S SE
Sbjct: 476 AYTTGSETTTASNTGLET---TTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532
Query: 905 GAT----GENLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGG 960
T G V + +T G E + S +G ET S+E + G
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGA--ETTTDSTEGSGTTAASTAG 590
Query: 961 DKSPSPSAAD---TTATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIAT 1015
++ + S AD TTA+ A + + TT + T TE + T T++T
Sbjct: 591 SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648
Score = 46.2 bits (108), Expect = 3e-04
Identities = 94/468 (20%), Positives = 165/468 (35%), Gaps = 34/468 (7%)
Query: 556 STTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQEAKTL 615
STT+ + S S E +T ++ ET TT +ATG + +T + ++T
Sbjct: 647 STTDSETTMVSTTGS-ERTITSTEGSET--TTVSATGSETTVSTEGSGTTTVSITGSETT 703
Query: 616 QTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSE 675
+ ST T EG ++ T T + + ET + S+ + S
Sbjct: 704 KVSTTGSE---TTTTSTEGSEITTASITGSE---TTTASTEGSETTTASTEGSETTSAST 757
Query: 676 PAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFRE 735
E + T +TT S + + + ++A T G + + + F E
Sbjct: 758 TGSETT--TASTTSSETTMASIMGSETTMAS-------TIGSETTKVSTASSKMTTVFTE 808
Query: 736 DLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENVCDEP 795
+ + + + A++ T S +P + S T + E
Sbjct: 809 NSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 796 RDREAVCAM----ECFEAGDQGTCFDTIDSLVGRPVDKYSPQ--EICSVDTELAEGQNKV 849
E A E A +G+ T S G S + EI +V T +E
Sbjct: 869 ESSETTTATTIGSETTTASTEGS-ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 850 SDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGE 909
++ + + E T VS T T S +G+ T+T T S T + G
Sbjct: 928 TEGSETTTASTEGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGS 981
Query: 910 NLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSA- 968
V + + G E + S++G + T + ++ + EG + + +A
Sbjct: 982 ETTTVSTAGSETTTASIEGSETTTVSSTGS-ETTTVSTTGTETTITSTEGSETTTVTTAG 1040
Query: 969 ADTTATPASYSSIVSFPWE-KPTTLTANNECFQATRETEDTSTVTIAT 1015
++TTA + S + E TT + T T D T T++T
Sbjct: 1041 SETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088
Score = 45.8 bits (107), Expect = 5e-04
Identities = 138/645 (21%), Positives = 208/645 (32%), Gaps = 73/645 (11%)
Query: 576 TQSDKRETSHTTAAATGRS----SHADARECAISTQAEQEAKTLQTSTDSVSKEGNTNCK 631
T + E S T A+T S + + E T A E KT T+ + NT
Sbjct: 433 TTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT--- 489
Query: 632 GEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPF--TGTTTI 689
G++ T+F + + + ET + + S+M S E + TG+ T
Sbjct: 490 --GLETTTVFT---IGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT 544
Query: 690 SFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDE 749
+ S G + + + SE+ + +G+ + S A E
Sbjct: 545 TVSTTG--LETTTTSTEGSEMTTVSTTGAETTTDSTEGS----------GTTAASTAGSE 592
Query: 750 TMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENVCDEPRDREAVCAMECFEA 809
T + + AD E + S E T + T +
Sbjct: 593 TTTVSTADSENTTASTAD-SETTSASTTGSETTTASTTSSETTTASTE------------ 639
Query: 810 GDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVS 869
G + T T DS S + I S TE +E VS S + E T VS
Sbjct: 640 GSETTTVSTTDSETTMVSTTGSERTITS--TEGSE-TTTVSATGSETTVSTEGSGTTTVS 696
Query: 870 ETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVHAGQ 929
T T K S G+ + + S T SE T A E S AST G
Sbjct: 697 ITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT----ASTEGSETTTAST--EGS 750
Query: 930 EQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKP 989
E S S +G T +S + S ++TT + S +
Sbjct: 751 ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT------- 803
Query: 990 TTLTANNECFQATRETEDTSTV-TIATEVHPAKYLAVSIPEDKHAGGTEERFPRASHEKV 1048
T T N+E A+ +T+TV T +E PA G+E AS E
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET--TTASTEGS 861
Query: 1049 SQFPSQVQLDHILSGATIKSTKELLCRAPSVPGVPHHVLQLPEGE-GFCSNSPLQVDNLS 1107
+ + + TI S S G E S ++ +S
Sbjct: 862 ETTTASTESSETTTATTIGSE----TTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917
Query: 1108 GDKSQTVDRADFRSYEENFQERGSE----TKQGVQQQSLSQQGS--LSAPDFQQSLPTTS 1161
S+T + S GSE + G + ++S +GS + T S
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977
Query: 1162 AAQEERNLVPTAHSPASSREGAGQR----SGWGTRVSVVAETAGE 1202
A E V TA S ++ G S G+ + V+ T E
Sbjct: 978 TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022
Score = 43.1 bits (100), Expect = 0.003
Identities = 131/663 (19%), Positives = 218/663 (32%), Gaps = 62/663 (9%)
Query: 379 SGMGCGSRVSGDAGPMVATAGFCGHHSQPQEVGVRSSRVSKHGPSSPQTGMTLILGPHQD 438
S G + AG TA G + G ++ VS G +T M +G
Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGT---ETTMVSAMGSETT 125
Query: 439 GTSSVTEQGRYKLPTAPEAAENDYPGIQ---GETRDSHQAREEFASDNLLNMDESVRETE 495
S+ + + E G + T DS + + + ET
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 496 MKLLSGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVRQPGMKGNPKKPNANLRE 555
+G + + ET G + + ++ G + +
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 556 STTEGTLHLCSAKESAEP--PLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQE-- 611
+T G+ ++ E +E T+ K T+ TT T +S + ST +
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305
Query: 612 AKTLQTSTDSVSKEGNTNCKGEGMQVNTLF----ETSQVPDWSDPPQVQVQETVRETISC 667
A T+ T VS + +V T+F ET + V T ET +
Sbjct: 306 ASTIGPETTKVSTASS--------EVTTVFAAGSETIRASTVGSETTT-VSTTGSETTTA 356
Query: 668 SQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDG 727
S M SE + + + + TTT S G AS T G + D
Sbjct: 357 SIMG--SETSTDSTTGSETTTASTE---GSETTTASTEGSEATTVSTTGSETTTVSITDS 411
Query: 728 NIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALT 787
E + ++S ET + + + +D A + S T T
Sbjct: 412 ETTTTCTEGSEMT-AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470
Query: 788 LENVCDEPRDREAVCAMEC-------FEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDT 840
E E A F G T T S + E+ +V T
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET--TAVSATGSEMTTVST 528
Query: 841 ELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISH 900
E +E + + ++ +T T VS T + T +S +G S M+ + T+
Sbjct: 529 EGSEN----TTVSTTGSET------TTVSTTGLETTTTSTEG-SEMTTVSTTGAETTTDS 577
Query: 901 TASEGATGENLAKVENSTYPLASTVH-----AGQEQPSPSNSGGLDETQLLSSENNPLVQ 955
T G T + A E +T A + + A E S S +G ET S+ ++
Sbjct: 578 TEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGS--ETTTASTTSSETTT 635
Query: 956 FKEGGDKSPSPSAADT----TATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTV 1011
G ++ + S D+ +T S +I S + TT++A + T TE + T
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS--ETTVSTEGSGTT 693
Query: 1012 TIA 1014
T++
Sbjct: 694 TVS 696
Score = 38.5 bits (88), Expect = 0.072
Identities = 47/156 (30%), Positives = 69/156 (44%), Gaps = 20/156 (12%)
Query: 866 TQVSETSV-STCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLAST 924
T SET+V ST S S + T+ +T + S T + TG + V
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTAD-SETTAASTTGSEMTTVFT-------- 179
Query: 925 VHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAA--DTTA--TPASYSS 980
AG E +PS +G ET +S+ + G ++ + S A +TTA T S ++
Sbjct: 180 --AGSETITPSTAG--SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235
Query: 981 IVSFPWEKPTTLTANNECFQATRETEDTSTVTIATE 1016
VS + T TA +E A+ TED+ T T TE
Sbjct: 236 KVSTAGSETTVSTAGSETTAAS--TEDSETNTAFTE 269
Score = 38.5 bits (88), Expect = 0.072
Identities = 118/619 (19%), Positives = 210/619 (33%), Gaps = 68/619 (10%)
Query: 440 TSSVTEQGRYKLPTAPEAAENDYPGIQGETRDSHQAREEFASDNLLNMDESVRETEMKLL 499
T+ V+ G T+ E +E I G ++ A E + + + S ET
Sbjct: 702 TTKVSTTGSETTTTSTEGSEITTASITGS--ETTTASTEGSETTTASTEGS--ETTSAST 757
Query: 500 SGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVRQPGMKGNP---KKPNANLRES 556
+G + + ET +G + + ++ +V K + + +
Sbjct: 758 TGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817
Query: 557 TTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQE---AK 613
T T + +A P T + T+ +T + ++ + E ++ E A
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877
Query: 614 TLQTSTDSVSKEGN--TNCKGEGMQVNTLF-ETSQVPDWSDPPQVQVQETVRETISCSQM 670
T+ + T + S EG+ T EG + T E S++ V T ET + S
Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEI--------TTVSTTGSETTTASTE 929
Query: 671 PAFSEPAGEESP------FTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQD 724
+ + A E TG+ TI+ S G + SE +
Sbjct: 930 GSETTTASTEGSELTTVSTTGSETITVSAEGS--ETTTVTTMGSETTTASTAGSETTTVS 987
Query: 725 RDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDT 784
G+ + ++S ET + + + E V+ A E T
Sbjct: 988 TAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS-TEGSETTTVTTAGSETTAV 1046
Query: 785 ALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAE 844
T + + G + T T D ++ + S T +
Sbjct: 1047 YTTGSETTTTSTEGSETTTVST--TGSETTTASTAD------LETTTVSTSGSGTTTAST 1098
Query: 845 GQNKVSDLCSSNDKTLEVFFQ----TQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISH 900
++ + + + KT + T VS TS T +S G+ + + T + T +S
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVST 1158
Query: 901 TASEGATGE------NLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLV 954
SE T E S AST AG E + S +G ET S+ +
Sbjct: 1159 IGSEATTSSAAGSEATTTSTEGSETTTAST--AGSETTTASTAG--SETTTASTSGSETN 1214
Query: 955 QFKEGGDKSPSPSAADTTATPA----SYSSIVSFPWEKPT------------TLTANNEC 998
G ++ +PS+A + A S ++I S +PT ++TA+
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGAT 1274
Query: 999 FQATRETEDTSTVTIATEV 1017
+T + T +T AT+V
Sbjct: 1275 AASTTVSSTTFVLTKATDV 1293
Score = 37.7 bits (86), Expect = 0.12
Identities = 84/460 (18%), Positives = 154/460 (33%), Gaps = 34/460 (7%)
Query: 575 LTQSDKRETSHTTAAATGRSSHADARECAISTQAEQE-AKTLQTSTDSVSKEGN--TNCK 631
+T S+ + S T + T S+ A T +E A T + T + S EG+ T+
Sbjct: 697 ITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSAS 756
Query: 632 GEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISF 691
G + T TS + + + T+ TI + + + FT + +
Sbjct: 757 TTGSETTTASTTSSETTMASI--MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTI 814
Query: 692 SNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETM 751
++ S A + T G + +G+ + + S + ET
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874
Query: 752 SPGVFSRHLPKDARADFREPVAVSVASPEPTDTA-----LTLENVCDEPRDREAVCAMEC 806
+ A + E S E T + +T + + E
Sbjct: 875 TATTIGSETTT-ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933
Query: 807 FEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAEGQNKVSDLCSSNDKTLEVFFQT 866
A +G+ T+ + + T AEG + ++ T T
Sbjct: 934 TTASTEGSELTTVSTTGSETI------------TVSAEGSETTTVTTMGSETTTA---ST 978
Query: 867 QVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVH 926
SET+ + S+ + + T+T + S T + TG +
Sbjct: 979 AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTT 1038
Query: 927 AGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAAD----TTATPASYSSIV 982
AG E + +G ET S+E + G ++ + S AD T +T S ++
Sbjct: 1039 AGSETTAVYTTG--SETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTA 1096
Query: 983 SFPWEKPTT--LTANNECFQATRETEDTSTVTIATEVHPA 1020
S + TT +T + +T +E T+ T ++E A
Sbjct: 1097 STAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTA 1136
Score = 35.0 bits (79), Expect = 0.80
Identities = 91/485 (18%), Positives = 152/485 (31%), Gaps = 82/485 (16%)
Query: 583 TSHTTAAATGRSSHADARECAISTQAEQEAKTLQTSTDSVSKEGNTNCKGEGMQVNTLFE 642
T+ TT++ T +S A + +ST + T+T + T G ++ T+F
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSE------TTTAYTADSETTAASTTGSEMTTVFT 179
Query: 643 TSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENA 702
ET+ + + S+ S AG E+ TT + H E
Sbjct: 180 AGS-------------ETITPSTAGSETTTVST-AGSETTTVSTTGSETTTASTAHSETT 225
Query: 703 SLAQH-----------SEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETM 751
+ + SE T G + D F ED K + + + T
Sbjct: 226 AASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA 285
Query: 752 SPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENV-----CDEPRDREAVCAMEC 806
+ S P A E S PE T + V R + E
Sbjct: 286 ASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343
Query: 807 FEAGDQGTCFDTI---------DSLVGRPVDKYSPQ--EICSVDTELAEG---------- 845
G+ T DS G S + E + TE +E
Sbjct: 344 TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403
Query: 846 ------QNKVSDLCSSNDKTLEVFF--------QTQVSETSVSTCKSSKDGNSVMSPLFT 891
++ + C+ + V T+ SE ++++ S+ + T
Sbjct: 404 TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSET 463
Query: 892 STFTLNISHTASEGATGENLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENN 951
+T T S T + TG N+ + G + + S G ET +S+ +
Sbjct: 464 TTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG--SETTAVSATGS 521
Query: 952 PLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTV 1011
+ G ++ + S + T S + + E TT T +E T T T
Sbjct: 522 EMTTVSTEGSENTTVSTTGSETTTVSTTGL-----ETTTTSTEGSE--MTTVSTTGAETT 574
Query: 1012 TIATE 1016
T +TE
Sbjct: 575 TDSTE 579
Score = 31.6 bits (70), Expect = 8.9
Identities = 32/154 (20%), Positives = 63/154 (40%), Gaps = 11/154 (7%)
Query: 869 SETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVHAG 928
S T+ ++ S+ ++ T+T + S T + TG V S + +T AG
Sbjct: 13 SNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAG 72
Query: 929 QEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEK 988
E + S++G T ++ + S + S T + + +++VS +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTV---------STAGSETTTVSITGTETTMVSAMGSE 123
Query: 989 PTT--LTANNECFQATRETEDTSTVTIATEVHPA 1020
TT T++ +T +E T+ T+ +E A
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTA 157
>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 48.1 bits (113), Expect = 9e-05
Identities = 112/520 (21%), Positives = 183/520 (35%), Gaps = 51/520 (9%)
Query: 556 STTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRS-----SHADARECAISTQAEQ 610
++TEG+ + AE T +D E S TTAA+T S S AD+ ST A+
Sbjct: 556 TSTEGSEMTTVSTTGAE---TTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST-ADS 611
Query: 611 EAKTL-----QTSTDSVSKEGNTNCKGEGMQVNTLF----ETSQVPDWSDPPQV---QVQ 658
E + +T+T S + T EG + T+ ET+ V + +
Sbjct: 612 ETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGS 671
Query: 659 ETVRETISCSQMPAFSEPAGEES-PFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGP 717
ET + + S+ +E +G + TG+ T S G + + + SE+ +
Sbjct: 672 ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGS--ETTTTSTEGSEITTASITG 729
Query: 718 QHEEKQDRDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVA 777
+G+ + S S ET + S + +A ++
Sbjct: 730 SETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG 789
Query: 778 SPEP-TDTALTLENVCDEPRDREAVCAMECFEAGDQGTC-FDTID-SLVGRPVDKYSPQE 834
S TA + + + E T +TI S G + E
Sbjct: 790 SETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTE 849
Query: 835 ICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTF 894
T EG + S++ T T SET+ ++ + S+ + T+T
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTAT---TIGSETTTASTEGSETTTTSTEGSETTTA 906
Query: 895 TLNISHTASEGATGE--NLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNP 952
+ S + TG A E S AST G E + S +G ET +S+E +
Sbjct: 907 STEGSEITTVSTTGSETTTASTEGSETTTAST--EGSELTTVSTTG--SETITVSAEGSE 962
Query: 953 LVQFKEGGDKSPSPSAA----DTTATPASYSSIVSFPWEKPTTL-----------TANNE 997
G ++ + S A T +T S ++ S + TT+ T E
Sbjct: 963 TTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022
Query: 998 CFQATRETEDTSTVTIATEVHPAKYLAVSIPEDKHAGGTE 1037
+ E +T+TVT A A Y S G+E
Sbjct: 1023 TTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSE 1062
Score = 46.2 bits (108), Expect = 3e-04
Identities = 96/478 (20%), Positives = 157/478 (32%), Gaps = 59/478 (12%)
Query: 555 ESTTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATG-RSSHADARECAISTQAEQEAK 613
E+TT T H + S T S TT + G ++ A + +T +++K
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272
Query: 614 TLQTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAF 673
T ST + E +T+ + + P +V E + A
Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV--FAAG 330
Query: 674 SEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNF 733
SE + + TTT+S + G AS+ T G +
Sbjct: 331 SETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDSTTGSE--------------- 372
Query: 734 REDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALT---LEN 790
+ S ET + A + E VS E T ++T
Sbjct: 373 ------TTTASTEGSETTT-----------ASTEGSEATTVSTTGSETTTVSITDSETTT 415
Query: 791 VCDEPRDREAVCA--MECFEAGDQG---TCFDTIDS-LVGRPVDKYSPQEICSVDTELAE 844
C E + AV E A +G T T DS + + + +E
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475
Query: 845 GQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASE 904
S+ ++++ LE T V T +S +G+ + T + +S SE
Sbjct: 476 AYTTGSETTTASNTGLET---TTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532
Query: 905 GAT----GENLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGG 960
T G V + +T G E + S +G ET S+E + G
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGA--ETTTDSTEGSGTTAASTAG 590
Query: 961 DKSPSPSAAD---TTATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTVTIAT 1015
++ + S AD TTA+ A + + TT + T TE + T T++T
Sbjct: 591 SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648
Score = 46.2 bits (108), Expect = 3e-04
Identities = 94/468 (20%), Positives = 165/468 (35%), Gaps = 34/468 (7%)
Query: 556 STTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQEAKTL 615
STT+ + S S E +T ++ ET TT +ATG + +T + ++T
Sbjct: 647 STTDSETTMVSTTGS-ERTITSTEGSET--TTVSATGSETTVSTEGSGTTTVSITGSETT 703
Query: 616 QTSTDSVSKEGNTNCKGEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSE 675
+ ST T EG ++ T T + + ET + S+ + S
Sbjct: 704 KVSTTGSE---TTTTSTEGSEITTASITGSE---TTTASTEGSETTTASTEGSETTSAST 757
Query: 676 PAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFRE 735
E + T +TT S + + + ++A T G + + + F E
Sbjct: 758 TGSETT--TASTTSSETTMASIMGSETTMAS-------TIGSETTKVSTASSKMTTVFTE 808
Query: 736 DLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENVCDEP 795
+ + + + A++ T S +P + S T + E
Sbjct: 809 NSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 796 RDREAVCAM----ECFEAGDQGTCFDTIDSLVGRPVDKYSPQ--EICSVDTELAEGQNKV 849
E A E A +G+ T S G S + EI +V T +E
Sbjct: 869 ESSETTTATTIGSETTTASTEGS-ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 850 SDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGE 909
++ + + E T VS T T S +G+ T+T T S T + G
Sbjct: 928 TEGSETTTASTEGSELTTVSTTGSETITVSAEGSE------TTTVTTMGSETTTASTAGS 981
Query: 910 NLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSA- 968
V + + G E + S++G + T + ++ + EG + + +A
Sbjct: 982 ETTTVSTAGSETTTASIEGSETTTVSSTGS-ETTTVSTTGTETTITSTEGSETTTVTTAG 1040
Query: 969 ADTTATPASYSSIVSFPWE-KPTTLTANNECFQATRETEDTSTVTIAT 1015
++TTA + S + E TT + T T D T T++T
Sbjct: 1041 SETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088
Score = 45.8 bits (107), Expect = 5e-04
Identities = 138/645 (21%), Positives = 208/645 (32%), Gaps = 73/645 (11%)
Query: 576 TQSDKRETSHTTAAATGRS----SHADARECAISTQAEQEAKTLQTSTDSVSKEGNTNCK 631
T + E S T A+T S + + E T A E KT T+ + NT
Sbjct: 433 TTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT--- 489
Query: 632 GEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPF--TGTTTI 689
G++ T+F + + + ET + + S+M S E + TG+ T
Sbjct: 490 --GLETTTVFT---IGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT 544
Query: 690 SFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDE 749
+ S G + + + SE+ + +G+ + S A E
Sbjct: 545 TVSTTG--LETTTTSTEGSEMTTVSTTGAETTTDSTEGS----------GTTAASTAGSE 592
Query: 750 TMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENVCDEPRDREAVCAMECFEA 809
T + + AD E + S E T + T +
Sbjct: 593 TTTVSTADSENTTASTAD-SETTSASTTGSETTTASTTSSETTTASTE------------ 639
Query: 810 GDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAEGQNKVSDLCSSNDKTLEVFFQTQVS 869
G + T T DS S + I S TE +E VS S + E T VS
Sbjct: 640 GSETTTVSTTDSETTMVSTTGSERTITS--TEGSE-TTTVSATGSETTVSTEGSGTTTVS 696
Query: 870 ETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVHAGQ 929
T T K S G+ + + S T SE T A E S AST G
Sbjct: 697 ITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT----ASTEGSETTTAST--EGS 750
Query: 930 EQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKP 989
E S S +G T +S + S ++TT + S +
Sbjct: 751 ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT------- 803
Query: 990 TTLTANNECFQATRETEDTSTV-TIATEVHPAKYLAVSIPEDKHAGGTEERFPRASHEKV 1048
T T N+E A+ +T+TV T +E PA G+E AS E
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET--TTASTEGS 861
Query: 1049 SQFPSQVQLDHILSGATIKSTKELLCRAPSVPGVPHHVLQLPEGE-GFCSNSPLQVDNLS 1107
+ + + TI S S G E S ++ +S
Sbjct: 862 ETTTASTESSETTTATTIGSE----TTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917
Query: 1108 GDKSQTVDRADFRSYEENFQERGSE----TKQGVQQQSLSQQGS--LSAPDFQQSLPTTS 1161
S+T + S GSE + G + ++S +GS + T S
Sbjct: 918 TTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAS 977
Query: 1162 AAQEERNLVPTAHSPASSREGAGQR----SGWGTRVSVVAETAGE 1202
A E V TA S ++ G S G+ + V+ T E
Sbjct: 978 TAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022
Score = 43.1 bits (100), Expect = 0.003
Identities = 131/662 (19%), Positives = 217/662 (32%), Gaps = 60/662 (9%)
Query: 379 SGMGCGSRVSGDAGPMVATAGFCGHHSQPQEVGVRSSRVSKHGPSSPQTGMTLILGPHQD 438
S G + AG TA G + G ++ VS G +T M +G
Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGT---ETTMVSAMGSETT 125
Query: 439 GTSSVTEQGRYKLPTAPEAAENDYPGIQ---GETRDSHQAREEFASDNLLNMDESVRETE 495
S+ + + E G + T DS + + + ET
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185
Query: 496 MKLLSGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVRQPGMKGNPKKPNANLRE 555
+G + + ET G + + ++ G + +
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 556 STTEGTLHLCSAKESAEP--PLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQE-- 611
+T G+ ++ E +E T+ K T+ TT T +S + ST +
Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305
Query: 612 AKTLQTSTDSVSKEGNTNCKGEGMQVNTLF----ETSQVPDWSDPPQVQVQETVRETISC 667
A T+ T VS + +V T+F ET + V T ET +
Sbjct: 306 ASTIGPETTKVSTASS--------EVTTVFAAGSETIRASTVGSETTT-VSTTGSETTTA 356
Query: 668 SQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDG 727
S M SE + + + + TTT S G AS T G + D
Sbjct: 357 SIMG--SETSTDSTTGSETTTASTE---GSETTTASTEGSEATTVSTTGSETTTVSITDS 411
Query: 728 NIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDTALT 787
E + ++S ET + + + +D A + S T T
Sbjct: 412 ETTTTCTEGSEMT-AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470
Query: 788 LENVCDEPRDREAVCAMEC-------FEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDT 840
E E A F G T T S + E+ +V T
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET--TAVSATGSEMTTVST 528
Query: 841 ELAEGQNKVSDLCSSNDKTLEVFFQTQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISH 900
E +E + + ++ +T T VS T + T +S +G S M+ + T+
Sbjct: 529 EGSEN----TTVSTTGSET------TTVSTTGLETTTTSTEG-SEMTTVSTTGAETTTDS 577
Query: 901 TASEGATGENLAKVENSTYPLASTVH-----AGQEQPSPSNSGGLDETQLLSSENNPLVQ 955
T G T + A E +T A + + A E S S +G ET S+ ++
Sbjct: 578 TEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGS--ETTTASTTSSETTT 635
Query: 956 FKEGGDKSPSPSAADT----TATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTV 1011
G ++ + S D+ +T S +I S + TT++A + E T+TV
Sbjct: 636 ASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTV 695
Query: 1012 TI 1013
+I
Sbjct: 696 SI 697
Score = 39.7 bits (91), Expect = 0.033
Identities = 119/619 (19%), Positives = 210/619 (33%), Gaps = 68/619 (10%)
Query: 440 TSSVTEQGRYKLPTAPEAAENDYPGIQGETRDSHQAREEFASDNLLNMDESVRETEMKLL 499
T+ V+ G T+ E +E I G ++ A E + + + S ET
Sbjct: 702 TTKVSTTGSETTTTSTEGSEITTASITGS--ETTTASTEGSETTTASTEGS--ETTSAST 757
Query: 500 SGESENSGMSQCWETAADKRVGGKDLWSKRGSRKSARVRQPGMKGNP---KKPNANLRES 556
+G + + ET +G + + ++ +V K + + +
Sbjct: 758 TGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817
Query: 557 TTEGTLHLCSAKESAEPPLTQSDKRETSHTTAAATGRSSHADARECAISTQAEQE---AK 613
T T + +A P T + T+ +T + ++ + E ++ E A
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877
Query: 614 TLQTSTDSVSKEGN--TNCKGEGMQVNTLF-ETSQVPDWSDPPQVQVQETVRETISCSQM 670
T+ + T + S EG+ T EG + T E S++ V T ET + S
Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEI--------TTVSTTGSETTTASTE 929
Query: 671 PAFSEPAGEESP------FTGTTTISFSNLGGVHKENASLAQHSEVKPCTCGPQHEEKQD 724
+ + A E TG+ TI+ S G + SE +
Sbjct: 930 GSETTTASTEGSELTTVSTTGSETITVSAEGS--ETTTVTTMGSETTTASTAGSETTTVS 987
Query: 725 RDGNIPDNFREDLKYEQSISEANDETMSPGVFSRHLPKDARADFREPVAVSVASPEPTDT 784
G+ + ++S ET + + + E V+ A E T
Sbjct: 988 TAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS-TEGSETTTVTTAGSETTAV 1046
Query: 785 ALTLENVCDEPRDREAVCAMECFEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAE 844
T + + G + T T D ++ + S T +
Sbjct: 1047 YTTGSETTTTSTEGSETTTVST--TGSETTTASTAD------LETTTVSTSGSGTTTAST 1098
Query: 845 GQNKVSDLCSSNDKTLEVFFQ----TQVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISH 900
++ + + + KT + T VS TS T +S G+ + + T + T +S
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVST 1158
Query: 901 TASEGATGE------NLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENNPLV 954
SE T E S AST AG E + S +G ET S+ +
Sbjct: 1159 IGSEATTSSAAGSEATTTSTEGSETTTAST--AGSETTTASTAG--SETTTASTSGSETN 1214
Query: 955 QFKEGGDKSPSPSAADTTATPA----SYSSIVSFPWEKPT------------TLTANNEC 998
G ++ +PS+A + A S S+I S +PT ++TA+
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGAT 1274
Query: 999 FQATRETEDTSTVTIATEV 1017
+T + T +T AT+V
Sbjct: 1275 AASTTVSSTTFVLTKATDV 1293
Score = 38.5 bits (88), Expect = 0.072
Identities = 47/156 (30%), Positives = 69/156 (44%), Gaps = 20/156 (12%)
Query: 866 TQVSETSV-STCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLAST 924
T SET+V ST S S + T+ +T + S T + TG + V
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTAD-SETTAASTTGSEMTTVFT-------- 179
Query: 925 VHAGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAA--DTTA--TPASYSS 980
AG E +PS +G ET +S+ + G ++ + S A +TTA T S ++
Sbjct: 180 --AGSETITPSTAG--SETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235
Query: 981 IVSFPWEKPTTLTANNECFQATRETEDTSTVTIATE 1016
VS + T TA +E A+ TED+ T T TE
Sbjct: 236 KVSTAGSETTVSTAGSETTAAS--TEDSETNTAFTE 269
Score = 37.7 bits (86), Expect = 0.12
Identities = 84/460 (18%), Positives = 154/460 (33%), Gaps = 34/460 (7%)
Query: 575 LTQSDKRETSHTTAAATGRSSHADARECAISTQAEQE-AKTLQTSTDSVSKEGN--TNCK 631
+T S+ + S T + T S+ A T +E A T + T + S EG+ T+
Sbjct: 697 ITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSAS 756
Query: 632 GEGMQVNTLFETSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISF 691
G + T TS + + + T+ TI + + + FT + +
Sbjct: 757 TTGSETTTASTTSSETTMASI--MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTI 814
Query: 692 SNLGGVHKENASLAQHSEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETM 751
++ S A + T G + +G+ + + S + ET
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874
Query: 752 SPGVFSRHLPKDARADFREPVAVSVASPEPTDTA-----LTLENVCDEPRDREAVCAMEC 806
+ A + E S E T + +T + + E
Sbjct: 875 TATTIGSETTT-ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933
Query: 807 FEAGDQGTCFDTIDSLVGRPVDKYSPQEICSVDTELAEGQNKVSDLCSSNDKTLEVFFQT 866
A +G+ T+ + + T AEG + ++ T T
Sbjct: 934 TTASTEGSELTTVSTTGSETI------------TVSAEGSETTTVTTMGSETTTA---ST 978
Query: 867 QVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVH 926
SET+ + S+ + + T+T + S T + TG +
Sbjct: 979 AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTT 1038
Query: 927 AGQEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAAD----TTATPASYSSIV 982
AG E + +G ET S+E + G ++ + S AD T +T S ++
Sbjct: 1039 AGSETTAVYTTG--SETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTA 1096
Query: 983 SFPWEKPTT--LTANNECFQATRETEDTSTVTIATEVHPA 1020
S + TT +T + +T +E T+ T ++E A
Sbjct: 1097 STAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTA 1136
Score = 35.0 bits (79), Expect = 0.80
Identities = 91/485 (18%), Positives = 152/485 (31%), Gaps = 82/485 (16%)
Query: 583 TSHTTAAATGRSSHADARECAISTQAEQEAKTLQTSTDSVSKEGNTNCKGEGMQVNTLFE 642
T+ TT++ T +S A + +ST + T+T + T G ++ T+F
Sbjct: 126 TNSTTSSETTVTSTAGSETTTVSTVGSE------TTTAYTADSETTAASTTGSEMTTVFT 179
Query: 643 TSQVPDWSDPPQVQVQETVRETISCSQMPAFSEPAGEESPFTGTTTISFSNLGGVHKENA 702
ET+ + + S+ S AG E+ TT + H E
Sbjct: 180 AGS-------------ETITPSTAGSETTTVST-AGSETTTVSTTGSETTTASTAHSETT 225
Query: 703 SLAQH-----------SEVKPCTCGPQHEEKQDRDGNIPDNFREDLKYEQSISEANDETM 751
+ + SE T G + D F ED K + + + T
Sbjct: 226 AASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA 285
Query: 752 SPGVFSRHLPKDARADFREPVAVSVASPEPTDTALTLENV-----CDEPRDREAVCAMEC 806
+ S P A E S PE T + V R + E
Sbjct: 286 ASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343
Query: 807 FEAGDQGTCFDTI---------DSLVGRPVDKYSPQ--EICSVDTELAEG---------- 845
G+ T DS G S + E + TE +E
Sbjct: 344 TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403
Query: 846 ------QNKVSDLCSSNDKTLEVFF--------QTQVSETSVSTCKSSKDGNSVMSPLFT 891
++ + C+ + V T+ SE ++++ S+ + T
Sbjct: 404 TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSET 463
Query: 892 STFTLNISHTASEGATGENLAKVENSTYPLASTVHAGQEQPSPSNSGGLDETQLLSSENN 951
+T T S T + TG N+ + G + + S G ET +S+ +
Sbjct: 464 TTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG--SETTAVSATGS 521
Query: 952 PLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEKPTTLTANNECFQATRETEDTSTV 1011
+ G ++ + S + T S + + E TT T +E T T T
Sbjct: 522 EMTTVSTEGSENTTVSTTGSETTTVSTTGL-----ETTTTSTEGSE--MTTVSTTGAETT 574
Query: 1012 TIATE 1016
T +TE
Sbjct: 575 TDSTE 579
Score = 31.6 bits (70), Expect = 8.9
Identities = 32/154 (20%), Positives = 63/154 (40%), Gaps = 11/154 (7%)
Query: 869 SETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVHAG 928
S T+ ++ S+ ++ T+T + S T + TG V S + +T AG
Sbjct: 13 SNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAG 72
Query: 929 QEQPSPSNSGGLDETQLLSSENNPLVQFKEGGDKSPSPSAADTTATPASYSSIVSFPWEK 988
E + S++G T ++ + S + S T + + +++VS +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTV---------STAGSETTTVSITGTETTMVSAMGSE 123
Query: 989 PTT--LTANNECFQATRETEDTSTVTIATEVHPA 1020
TT T++ +T +E T+ T+ +E A
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTA 157
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,025,708
Number of Sequences: 37866
Number of extensions: 4460146
Number of successful extensions: 16228
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 297
Number of HSP's that attempted gapping in prelim test: 13289
Number of HSP's gapped (non-prelim): 2933
length of query: 2170
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2052
effective length of database: 13,779,330
effective search space: 28275185160
effective search space used: 28275185160
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.