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Search of human proteins with 148539848
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
(839 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 1697 0.0
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 1681 0.0
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 1146 0.0
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 1132 0.0
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 822 0.0
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 808 0.0
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 412 e-115
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 396 e-110
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 347 2e-95
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 344 2e-94
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 342 1e-93
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 339 5e-93
gi|116534898 desmoglein 2 preproprotein [Homo sapiens] 320 3e-87
gi|197313787 desmoglein 4 isoform 1 [Homo sapiens] 310 4e-84
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] 310 4e-84
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 289 9e-78
gi|119964718 desmoglein 3 preproprotein [Homo sapiens] 285 9e-77
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 262 9e-70
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 261 1e-69
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 261 1e-69
gi|119703744 desmoglein 1 preproprotein [Homo sapiens] 253 5e-67
gi|221316595 cadherin 17 precursor [Homo sapiens] 246 5e-65
gi|221316593 cadherin 17 precursor [Homo sapiens] 246 5e-65
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 244 3e-64
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 243 7e-64
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 240 5e-63
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 234 3e-61
gi|16753221 cadherin 22 precursor [Homo sapiens] 232 9e-61
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 229 6e-60
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 216 7e-56
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 1697 bits (4395), Expect = 0.0
Identities = 839/839 (100%), Positives = 839/839 (100%)
Query: 1 MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRS 60
MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRS
Sbjct: 1 MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRS 60
Query: 61 ADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVS 120
ADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVS
Sbjct: 61 ADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVS 120
Query: 121 KTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDK 180
KTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDK
Sbjct: 121 KTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDK 180
Query: 181 EPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNH 240
EPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNH
Sbjct: 181 EPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNH 240
Query: 241 PVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPS 300
PVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPS
Sbjct: 241 PVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPS 300
Query: 301 TGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAY 360
TGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAY
Sbjct: 301 TGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAY 360
Query: 361 EAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVV 420
EAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVV
Sbjct: 361 EAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVV 420
Query: 421 KPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRI 480
KPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRI
Sbjct: 421 KPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRI 480
Query: 481 KENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETP 540
KENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETP
Sbjct: 481 KENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETP 540
Query: 541 KNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPD 600
KNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPD
Sbjct: 541 KNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPD 600
Query: 601 EPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAA 660
EPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAA
Sbjct: 601 EPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAA 660
Query: 661 TKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKG 720
TKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKG
Sbjct: 661 TKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKG 720
Query: 721 KRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIE 780
KRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIE
Sbjct: 721 KRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIE 780
Query: 781 MMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIRGHTG 839
MMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIRGHTG
Sbjct: 781 MMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIRGHTG 839
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 1681 bits (4353), Expect = 0.0
Identities = 831/832 (99%), Positives = 832/832 (100%)
Query: 1 MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRS 60
MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRS
Sbjct: 1 MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRS 60
Query: 61 ADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVS 120
ADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVS
Sbjct: 61 ADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVS 120
Query: 121 KTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDK 180
KTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDK
Sbjct: 121 KTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDK 180
Query: 181 EPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNH 240
EPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNH
Sbjct: 181 EPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNH 240
Query: 241 PVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPS 300
PVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPS
Sbjct: 241 PVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPS 300
Query: 301 TGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAY 360
TGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAY
Sbjct: 301 TGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAY 360
Query: 361 EAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVV 420
EAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVV
Sbjct: 361 EAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVV 420
Query: 421 KPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRI 480
KPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRI
Sbjct: 421 KPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRI 480
Query: 481 KENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETP 540
KENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETP
Sbjct: 481 KENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETP 540
Query: 541 KNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPD 600
KNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPD
Sbjct: 541 KNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPD 600
Query: 601 EPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAA 660
EPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAA
Sbjct: 601 EPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAA 660
Query: 661 TKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKG 720
TKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKG
Sbjct: 661 TKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKG 720
Query: 721 KRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIE 780
KRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIE
Sbjct: 721 KRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIE 780
Query: 781 MMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEE 832
MMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGE+
Sbjct: 781 MMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEK 832
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 1146 bits (2965), Expect = 0.0
Identities = 560/843 (66%), Positives = 669/843 (79%), Gaps = 5/843 (0%)
Query: 1 MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRS 60
M AA P S GA+C LLLTL I A +ACK V L+VPSKL+A+K++GRVNL+ECF +
Sbjct: 1 MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTA 60
Query: 61 ADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVS 120
A+LI SSDPDF++L DGSVYT + LS +KRSFTI LS+ Q +K++ V LEHQ KV
Sbjct: 61 ANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVL 120
Query: 121 KTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDK 180
K RHT+E VLRRAKRRWAPIPCSM ENSLGPFPLFLQQV+SD AQNYT++YSI G GVD+
Sbjct: 121 KKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQ 180
Query: 181 EPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNH 240
EP NLFY+ERDTGNL+CTRPVDRE+Y+ F++IA+A+T DGY+ +LPLPL I++EDENDN+
Sbjct: 181 EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY 240
Query: 241 PVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPS 300
P+FTE Y F + E+ R GTTVG VCATD+DEPDTMHTRLKYSI+ Q P SP LFS+HP+
Sbjct: 241 PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPT 300
Query: 301 TGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAY 360
TGVITT S LDRE++DKY L +KVQDMDGQ+FGL TSTCII + D ND+ PTF + +Y
Sbjct: 301 TGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY 360
Query: 361 EAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVV 420
VEEN +VEILR+ +EDKDL+NTANWR N+TILKGNENG+FKI TD +TNEGVL VV
Sbjct: 361 VTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVV 420
Query: 421 KPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRI 480
KPLNYEE +Q+ L+IGV NEAPF+R+ +A++ A VTV+V D DEGPEC P Q VR+
Sbjct: 421 KPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRM 480
Query: 481 KENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETP 540
KEN VG+ NGYKAYDPE R+ +G+RYKKL DP GW+TIDE +GSI + LDRE ET
Sbjct: 481 KENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETI 540
Query: 541 KNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPD 600
KN +YNITVLA D+ R+CTGTL + ++DVNDN P I ++ V+ICKP M +I+AVDPD
Sbjct: 541 KNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPD 600
Query: 601 EPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAA 660
EP+HG PF FSL +++ E+ R+W L +NDTAARLSYQ + F Y +PITV+DR G ++
Sbjct: 601 EPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSS 660
Query: 661 TKLLRVNLCECTHPTQC--RATSR--STGVILGKWAILAILLGIALLFSVLLTLVCGVFG 716
L V LC+C C R R GV LGKWAILAILLGIALLF +L TLVCG G
Sbjct: 661 VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
Query: 717 ATK-GKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGG 775
+K K P+DLAQQNLI+SNTEAPGDD+V SANGF TQT S+QG CGT+GSG+KNGG
Sbjct: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGG 780
Query: 776 QETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIR 835
QETIEM+KGG+QT ESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIR
Sbjct: 781 QETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIR 840
Query: 836 GHT 838
GHT
Sbjct: 841 GHT 843
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 1132 bits (2929), Expect = 0.0
Identities = 553/837 (66%), Positives = 663/837 (79%), Gaps = 5/837 (0%)
Query: 1 MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRS 60
M AA P S GA+C LLLTL I A +ACK V L+VPSKL+A+K++GRVNL+ECF +
Sbjct: 1 MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTA 60
Query: 61 ADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLEHQKKVS 120
A+LI SSDPDF++L DGSVYT + LS +KRSFTI LS+ Q +K++ V LEHQ KV
Sbjct: 61 ANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVL 120
Query: 121 KTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDK 180
K RHT+E VLRRAKRRWAPIPCSM ENSLGPFPLFLQQV+SD AQNYT++YSI G GVD+
Sbjct: 121 KKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQ 180
Query: 181 EPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNH 240
EP NLFY+ERDTGNL+CTRPVDRE+Y+ F++IA+A+T DGY+ +LPLPL I++EDENDN+
Sbjct: 181 EPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNY 240
Query: 241 PVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPS 300
P+FTE Y F + E+ R GTTVG VCATD+DEPDTMHTRLKYSI+ Q P SP LFS+HP+
Sbjct: 241 PIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPT 300
Query: 301 TGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAY 360
TGVITT S LDRE++DKY L +KVQDMDGQ+FGL TSTCII + D ND+ PTF + +Y
Sbjct: 301 TGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSY 360
Query: 361 EAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVV 420
VEEN +VEILR+ +EDKDL+NTANWR N+TILKGNENG+FKI TD +TNEGVL VV
Sbjct: 361 VTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVV 420
Query: 421 KPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRI 480
KPLNYEE +Q+ L+IGV NEAPF+R+ +A++ A VTV+V D DEGPEC P Q VR+
Sbjct: 421 KPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRM 480
Query: 481 KENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETP 540
KEN VG+ NGYKAYDPE R+ +G+RYKKL DP GW+TIDE +GSI + LDRE ET
Sbjct: 481 KENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETI 540
Query: 541 KNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPD 600
KN +YNITVLA D+ R+CTGTL + ++DVNDN P I ++ V+ICKP M +I+AVDPD
Sbjct: 541 KNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPD 600
Query: 601 EPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAA 660
EP+HG PF FSL +++ E+ R+W L +NDTAARLSYQ + F Y +PITV+DR G ++
Sbjct: 601 EPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSS 660
Query: 661 TKLLRVNLCECTHPTQC--RATSR--STGVILGKWAILAILLGIALLFSVLLTLVCGVFG 716
L V LC+C C R R GV LGKWAILAILLGIALLF +L TLVCG G
Sbjct: 661 VTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASG 720
Query: 717 ATK-GKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGG 775
+K K P+DLAQQNLI+SNTEAPGDD+V SANGF TQT S+QG CGT+GSG+KNGG
Sbjct: 721 TSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGG 780
Query: 776 QETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEE 832
QETIEM+KGG+QT ESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGE+
Sbjct: 781 QETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEK 837
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 822 bits (2123), Expect = 0.0
Identities = 428/834 (51%), Positives = 576/834 (69%), Gaps = 20/834 (2%)
Query: 15 CLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRSADLIRSSDPDFRVL 74
C LL +L++ + +AC+KV L VPS L+A+ ++G+VNLEEC +SA LIRSSDP FR+L
Sbjct: 13 CKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSASLIRSSDPAFRIL 72
Query: 75 NDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLE-HQKKVSKTRHTRETVLRRA 133
DGS+YT + LS +++SF+I+LSD +++ Q+E+ V+L + K K RHT++T L+R+
Sbjct: 73 EDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPKKRHTKDTALKRS 132
Query: 134 KRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTG 193
KRRWAPIP S+ ENSLGPFP +QQ++SDAAQNYT+FYSISG GVDKEP NLFYIE+DTG
Sbjct: 133 KRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYIEKDTG 192
Query: 194 NLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVL 253
++FCTR +DRE+Y+ F L YA+TADGY+ + PLPL I++ED+NDN P F + F V
Sbjct: 193 DIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVP 252
Query: 254 ESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDR 313
E+ R GT+VG V ATD DEPDT+HTRLKY ILQQ P P FS+HP TGVITT + +LDR
Sbjct: 253 ENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVITTTTPFLDR 312
Query: 314 EVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEI 373
E D Y LIM+V+DM GQ FGL T T I++ D NDN P+F + +Y VEEN +VEI
Sbjct: 313 EKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENRIDVEI 372
Query: 374 LRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNL 433
LR+ ++D+DL NT + + + IL+GNENG+F ISTD TNEGVL VVKPLNYE NRQV L
Sbjct: 373 LRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVIL 432
Query: 434 EIGVNNEAPFARDIPRVT-ALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKING 492
++GV NEA F++ T + VTV + D DEGPEC P + ++ ++ G ++ G
Sbjct: 433 QVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLG 492
Query: 493 YKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAI 552
YKA DPE +G GLRY+KL D W I++ +G + T K+LDRE + KN YNI+V+A+
Sbjct: 493 YKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVAV 552
Query: 553 DKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGAPFYFSL 612
D RSCTGTL V+++D ND+ P+I +E V IC+ + + VDPD P +G PF F L
Sbjct: 553 DAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKPVDPDGPENGPPFQFFL 611
Query: 613 PNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKLLRVNLCECT 672
N++ S+ W++ + + A L ++N + Y++PI +KDR G AT +L V +C+C+
Sbjct: 612 DNSA---SKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDCS 668
Query: 673 HPTQCRATSRST-----GVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDL 727
P++CR +ST VILG+WAILA++LG LL +L T C T K FPED+
Sbjct: 669 TPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRTVKKCFPEDI 728
Query: 728 AQQNLIISNTEAPGDDRVCSANGFMTQTTNN---SSQGFCGTMGSGMKNGGQETIEMMKG 784
AQQNLI+SNTE PG++ V AN + T+N +S G G+K Q++ EM+KG
Sbjct: 729 AQQNLIVSNTEGPGEE-VTEANIRLPMQTSNICDTSMSVGTVGGQGIKT--QQSFEMVKG 785
Query: 785 GNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIRGHT 838
G TL+S +G G H TL+S + G + D RY Y++W SFTQPRLGEESIRGHT
Sbjct: 786 G-YTLDSNKGGG-HQTLESVK-GVGQGDTGRYAYTDWQSFTQPRLGEESIRGHT 836
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 808 bits (2087), Expect = 0.0
Identities = 421/828 (50%), Positives = 570/828 (68%), Gaps = 20/828 (2%)
Query: 15 CLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRSADLIRSSDPDFRVL 74
C LL +L++ + +AC+KV L VPS L+A+ ++G+VNLEEC +SA LIRSSDP FR+L
Sbjct: 13 CKQLLFSLLVLTLLCDACQKVYLRVPSHLQAETLVGKVNLEECLKSASLIRSSDPAFRIL 72
Query: 75 NDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLE-HQKKVSKTRHTRETVLRRA 133
DGS+YT + LS +++SF+I+LSD +++ Q+E+ V+L + K K RHT++T L+R+
Sbjct: 73 EDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKSPKKRHTKDTALKRS 132
Query: 134 KRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTG 193
KRRWAPIP S+ ENSLGPFP +QQ++SDAAQNYT+FYSISG GVDKEP NLFYIE+DTG
Sbjct: 133 KRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYIEKDTG 192
Query: 194 NLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVL 253
++FCTR +DRE+Y+ F L YA+TADGY+ + PLPL I++ED+NDN P F + F V
Sbjct: 193 DIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVP 252
Query: 254 ESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDR 313
E+ R GT+VG V ATD DEPDT+HTRLKY ILQQ P P FS+HP TGVITT + +LDR
Sbjct: 253 ENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVITTTTPFLDR 312
Query: 314 EVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEI 373
E D Y LIM+V+DM GQ FGL T T I++ D NDN P+F + +Y VEEN +VEI
Sbjct: 313 EKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENRIDVEI 372
Query: 374 LRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNL 433
LR+ ++D+DL NT + + + IL+GNENG+F ISTD TNEGVL VVKPLNYE NRQV L
Sbjct: 373 LRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVIL 432
Query: 434 EIGVNNEAPFARDIPRVT-ALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKING 492
++GV NEA F++ T + VTV + D DEGPEC P + ++ ++ G ++ G
Sbjct: 433 QVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLG 492
Query: 493 YKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAI 552
YKA DPE +G GLRY+KL D W I++ +G + T K+LDRE + KN YNI+V+A+
Sbjct: 493 YKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVAV 552
Query: 553 DKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGAPFYFSL 612
D RSCTGTL V+++D ND+ P+I +E V IC+ + + VDPD P +G PF F L
Sbjct: 553 DAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKPVDPDGPENGPPFQFFL 611
Query: 613 PNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKLLRVNLCECT 672
N++ S+ W++ + + A L ++N + Y++PI +KDR G AT +L V +C+C+
Sbjct: 612 DNSA---SKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDCS 668
Query: 673 HPTQCRATSRST-----GVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDL 727
P++CR +ST VILG+WAILA++LG LL +L T C T K FPED+
Sbjct: 669 TPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRTVKKCFPEDI 728
Query: 728 AQQNLIISNTEAPGDDRVCSANGFMTQTTNN---SSQGFCGTMGSGMKNGGQETIEMMKG 784
AQQNLI+SNTE PG++ V AN + T+N +S G G+K Q++ EM+KG
Sbjct: 729 AQQNLIVSNTEGPGEE-VTEANIRLPMQTSNICDTSMSVGTVGGQGIKT--QQSFEMVKG 785
Query: 785 GNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEE 832
G TL+S +G G H TL+S + G + D RY Y++W SFTQPRLGE+
Sbjct: 786 G-YTLDSNKGGG-HQTLESVK-GVGQGDTGRYAYTDWQSFTQPRLGEK 830
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 412 bits (1059), Expect = e-115
Identities = 251/710 (35%), Positives = 378/710 (53%), Gaps = 33/710 (4%)
Query: 66 SSDP-DFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLE-----HQKKV 119
SS+P DF+V DG VY R+ LS + F I+ DK Q + +V V L ++ V
Sbjct: 73 SSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLKPTLTEESV 132
Query: 120 SKTRHTRETV-----------LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYT 168
++ E V L+R KR W P ++ ENS GPFP L ++ SD +N +
Sbjct: 133 KESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLS 192
Query: 169 VFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLP 228
+ YS++G G D+ P +F I +G L T+P+DRE+ F L A+A +G + P+
Sbjct: 193 LRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPID 252
Query: 229 LPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQT 288
+ I V D NDN P F ++N V E S+PGT V V A D D+P+ ++ L+Y I+ Q
Sbjct: 253 IVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQA 312
Query: 289 PR--SPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQ-FFGLIGTSTCIITV 345
P SP +F+++ TG I TV+ LDRE V +Y+LI++ DM+G +GL T+T +ITV
Sbjct: 313 PSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITV 372
Query: 346 TDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFK 405
TD NDN P F + V EN ++ + + + DKD +T W + I G+ G F
Sbjct: 373 TDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFA 432
Query: 406 ISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDL 465
I TD +N+G+++VVKP+++E NR L + N+ P A+ I + A V+V V D+
Sbjct: 433 IQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQH-PPQSTATVSVTVIDV 491
Query: 466 DEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISG 525
+E P P + +R +E L G+ + + A DP+ +RY KL DP W+ ID ++G
Sbjct: 492 NENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNG 551
Query: 526 SIITSKILDREVETPKNELYNITVLAIDK--DDRSCTGTLAVNIEDVNDNPPEILQEYVV 583
I T +LDRE KN +YN T LA D S TGTL + + D+NDN P++L +
Sbjct: 552 QITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAE 611
Query: 584 ICK-PKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQ---K 639
C+ P +I A+D D + PF F LP + I R W++T++N A+L+ +
Sbjct: 612 TCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFL 671
Query: 640 NAGFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLG 699
AG E I IT ++ +LRV +C+C C R G LG AI+AILL
Sbjct: 672 EAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLC 731
Query: 700 IALLFSVLLTLVCGVFGATKGKRF------PEDLAQQNLIISNTEAPGDD 743
I +L ++L V + K ++ PED + N++ + E G++
Sbjct: 732 IIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEE 781
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 396 bits (1018), Expect = e-110
Identities = 247/747 (33%), Positives = 394/747 (52%), Gaps = 50/747 (6%)
Query: 43 LEADKIIGRVNLEECFRSADL-IRSSDPDFRVLNDGSVYTARAVALSDKKRSFTI--WLS 99
LE +K++ +V C + ++ DF+V DG+V+ R + + ++ +FT+ W S
Sbjct: 49 LEGEKLL-QVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDS 107
Query: 100 DKRKQTQKEVTVLLE--------HQKKVSKT------------------RHTRETVLRRA 133
++ V +L+ H+ + K +H LRR
Sbjct: 108 QTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRR 167
Query: 134 KRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTG 193
KR W P ++ ENS GPFP L ++ SD + + YSI+G G D+ P+ +F I+ +G
Sbjct: 168 KRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSG 227
Query: 194 NLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVL 253
++ TRP+DREE+ + L A+A +G + P+ L I V D NDN P F +YN V
Sbjct: 228 RMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVD 287
Query: 254 ESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSP--GLFSVHPSTGVITTVSHYL 311
E S+PGT V V A D D+ T + ++Y I+ QTP+SP +F+++ TG I TV+ L
Sbjct: 288 EGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGL 347
Query: 312 DREVVDKYSLIMKVQDMDGQF-FGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFN 370
DRE V +Y++I++ DM+G +GL T+T IITVTD NDN P F + + V EN
Sbjct: 348 DREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVE 407
Query: 371 VEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQ 430
+ + + D+D ++ NW + I+ G+ +GHF + TD TNEG+++VVK ++YE NR
Sbjct: 408 TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRA 467
Query: 431 VNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKI 490
L + V+N+AP A I +++ + A VT+ + D++E P + +R++E + G+ +
Sbjct: 468 FMLTVMVSNQAPLASGI-QMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVL 526
Query: 491 NGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVL 550
+ A DP+ +RY KL DP W+ I+ +G I T+ +LDRE KN +Y T L
Sbjct: 527 TTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFL 586
Query: 551 AIDK--DDRSCTGTLAVNIEDVNDNPPEILQEYVVIC-KPKMGYTDILAVDPDEPVHGAP 607
A D S TGTL + + D+NDN PE+L + IC KP + +I A D D + P
Sbjct: 587 AADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGP 646
Query: 608 FYFSLPNTSPEISRLWSLTKVNDTAARLSYQ---KNAGFQEYTIPITVKDRAGQ--AATK 662
+ F LP + + W++T++N A+LS + AG Y +PI V D + T
Sbjct: 647 YVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGM--YDVPIIVTDSGNPPLSNTS 704
Query: 663 LLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKR 722
+++V +C C C LG AI+AIL+ I +L +++L V + K +
Sbjct: 705 IIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERH 764
Query: 723 F------PEDLAQQNLIISNTEAPGDD 743
PED + N++ + E G++
Sbjct: 765 TKQLLIDPEDDVRDNILKYDEEGGGEE 791
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 347 bits (891), Expect = 2e-95
Identities = 213/621 (34%), Positives = 325/621 (52%), Gaps = 18/621 (2%)
Query: 129 VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYI 188
+LRR KR W P S+ EN GPFP L Q++S+ ++ +FYSI+G G D P +F +
Sbjct: 101 ILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAV 160
Query: 189 ERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIY 248
E++TG L +P+DREE ++L +A + +G S + P+ + I V D+ND+ P FT+ +
Sbjct: 161 EKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTF 220
Query: 249 NFEVLESSRPGTTVGVVCATDRDEP-DTMHTRLKYSILQQTPRSPG--LFSVHPSTGVIT 305
VLE PGT+V V ATD D+ T + + YSI Q P+ P +F++H STG I+
Sbjct: 221 RGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTIS 280
Query: 306 TVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVE 365
+S LDRE V +Y+L ++ DMDG G T+ ++ + D+NDNAP F YEA V
Sbjct: 281 VISSGLDREKVPEYTLTIQATDMDGD--GSTTTAVAVVEILDANDNAPMFDPQKYEAHVP 338
Query: 366 ENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNY 425
ENA E+ R+ + D D N+ WR + I+ G++ HF I+T E+N+G+L+ K L++
Sbjct: 339 ENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDF 398
Query: 426 EENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLA 485
E Q L + V NEAPF +P T A + VHV D++E P P ++ V ++E +
Sbjct: 399 EAKNQHTLYVEVTNEAPFVLKLPTST----ATIVVHVEDVNEAPVFVPPSKVVEVQEGIP 454
Query: 486 VGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVET-PKNEL 544
G + Y A DP+ N + Y+ L DP GW+ +D SG + LDRE E +N +
Sbjct: 455 TGEPVCVYTAEDPDKEN-QKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNI 513
Query: 545 YNITVLAIDKDD--RSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEP 602
Y + VLA+D + TGTL + + DVND+ P + IC + D D
Sbjct: 514 YEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLS 573
Query: 603 VHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATK 662
H +PF L + S +I + + DT LS +K Y + +++ D +
Sbjct: 574 PHTSPFQAQLTDDS-DIYWTAEVNEEGDTVV-LSLKKFLKQDTYDVHLSLSDHGNKEQLT 631
Query: 663 LLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKR 722
++R +C+C + G IL +L +L + L VLL LV +
Sbjct: 632 VIRATVCDCHGHVETCPGPWKGGFIL---PVLGAVLALLFLLLVLLLLVRKKRKIKEPLL 688
Query: 723 FPEDLAQQNLIISNTEAPGDD 743
PED + N+ E G++
Sbjct: 689 LPEDDTRDNVFYYGEEGGGEE 709
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 344 bits (883), Expect = 2e-94
Identities = 235/637 (36%), Positives = 334/637 (52%), Gaps = 29/637 (4%)
Query: 126 RETVLRRAKRRWAPIPCSMQENSLG-PFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLN 184
R L R +R W P S+ EN P+PL Q++SD Q +V YSI G GVD+EP
Sbjct: 36 RAPALSRVRRAWVIPPISVSENHKRLPYPLV--QIKSDKQQLGSVIYSIQGPGVDEEPRG 93
Query: 185 LFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFT 244
+F I++ TG +F +DRE+ D F L A+A G + + P L I V D+NDN P F
Sbjct: 94 VFSIDKFTGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFL 153
Query: 245 EAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVI 304
+ + VLE + PGT V ATD D+P+T + L++SILQQ SP LFS+ TG I
Sbjct: 154 QEAFTGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQ--GSPELFSIDELTGEI 211
Query: 305 TTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFV 364
TV LDREVV Y+L ++V DM G GL T++ IIT+ D NDNAP F ++ +
Sbjct: 212 RTVQVGLDREVVAVYNLTLQVADMSGD--GLTATASAIITLDDINDNAPEFTRDEFFMEA 269
Query: 365 EENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLN 424
E V++ R+ +ED+DL + NW FTIL+G+ +G F I TD +TNEGVLS+VK L+
Sbjct: 270 IEAVSGVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALD 329
Query: 425 YEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENL 484
YE L++ V NEAP R +A V VHV+D +E P + E
Sbjct: 330 YESCEHYELKVSVQNEAPLQAAALRAER-GQAKVRVHVQDTNEPPVFQENPLRTSLAEGA 388
Query: 485 AVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNEL 544
G+ + + A DP+ L Y K +DP+ W+ +D +G I T +L K
Sbjct: 389 PPGTLVATFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGW 448
Query: 545 YNITVLAID--KDDRSCTGTLAVNIEDVNDNPPEIL--QEYVVICKPKMGYTDIL-AVDP 599
Y VLA D R+ TGTL++ I +VND+ P + + +P G +L A D
Sbjct: 449 YRAIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGLLLGATDE 508
Query: 600 DEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARL--SYQKNAGFQEYTIPITVKDRAG 657
D P HGAPF+F L PE+ R WSL++VN + ARL +Q G ++ + +
Sbjct: 509 DLPPHGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPRHQVPEGLHRLSLLLRDSGQPP 568
Query: 658 QAATKLLRVNLCECTH-----PTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLV- 711
Q + L V +C C P + TG+ LG L I+L ALL VL+ LV
Sbjct: 569 QQREQPLNVTVCRCGKDGVCLPGAAALLAGGTGLSLG---ALVIVLASALLLLVLVLLVA 625
Query: 712 --CGVFGATKGKRF---PEDLAQQNLIISNTEAPGDD 743
+ ++GK P+D + N++ + + G++
Sbjct: 626 LRARFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEE 662
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 342 bits (876), Expect = 1e-93
Identities = 224/655 (34%), Positives = 346/655 (52%), Gaps = 30/655 (4%)
Query: 37 LNVPSKLEADKIIGRVNLEECFRSADLIRS--SDPDFRVLNDGSVYTARAVALSDKKRSF 94
+N P++ D+ I + +C + D +R S P F+V +DG + R + K
Sbjct: 38 INQPAEFIEDQSILNLTFSDC-KGNDKLRYEVSSPYFKVNSDGGLVALRNITAVGK---- 92
Query: 95 TIWLSDKRKQTQKEVTVLLEHQKKVSKT-----RHTRETVLRRAKRRWAPIPCSMQENSL 149
T+++ + + +++ K + + + R + + R KR P + EN
Sbjct: 93 TLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQR 152
Query: 150 GPFPLFLQQV-ESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDV 208
PFP + +V +SD + + ++G+GVD+EP +F I +TG++ TR +DRE V
Sbjct: 153 QPFPRDVGKVVDSDRPERSK--FRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAV 210
Query: 209 FDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCAT 268
+ L + +G + + P+PL + V D+NDN P+F E Y V+E S GTTV + A
Sbjct: 211 YQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAF 270
Query: 269 DRDEPDTMHTRLKYSILQQTPR--SPGLFSVHPSTGVITTVSH--YLDREVVD--KYSLI 322
D D+P T + L+Y+I QQTP SP +F + P G I TV LDRE ++ KY LI
Sbjct: 271 DADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELI 330
Query: 323 MKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKD 382
++ QDM G GL GT+T I + D ND++P F + ++A VEE A V I+ + +EDKD
Sbjct: 331 IEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGV-IVNLTVEDKD 389
Query: 383 LINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAP 442
T WR +TI+ GN F+I T+ +TNEG+LSVVKPL+YE + L I V NE P
Sbjct: 390 DPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDP 449
Query: 443 FARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRN 502
D+ + + A V + V D++EGP P V +E+L+VGS + A DP++
Sbjct: 450 LVPDVSYGPS-STATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQ 508
Query: 503 GNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAIDKDDRSCTGT 562
+RY DP GW+ I+ I+G++ T+ +LDRE N +Y LAID + TGT
Sbjct: 509 HQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGT 568
Query: 563 --LAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGA--PFYFSLPNTSPE 618
L + +EDVNDN P I +C + ++ D+ +H PF F + +
Sbjct: 569 GTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVP 628
Query: 619 ISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKL--LRVNLCEC 671
++W ++K+N+T A +S +N Y +PI V D T + LRV +C C
Sbjct: 629 -DKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSC 682
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 339 bits (870), Expect = 5e-93
Identities = 238/728 (32%), Positives = 364/728 (50%), Gaps = 37/728 (5%)
Query: 43 LEADKIIGRVNLEECF-RSADLIRSSDPDFRVLNDGSVYTARAVALSDKKRSFTI--WLS 99
LE +++GRVN E+C R S D F+V DG + R + + + F + W S
Sbjct: 46 LERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDS 105
Query: 100 DKRKQTQKEVTVLL-------EHQKKVSKTRHTRETV------LRRAKRRWAPIPCSMQE 146
RK + K + HQ VS + T LRR KR W P S E
Sbjct: 106 TYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPE 165
Query: 147 NSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEY 206
N GPFP L Q++S+ + VFYSI+G+G D P+ +F IER+TG L T P+DRE
Sbjct: 166 NEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERI 225
Query: 207 DVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVC 266
+ L ++A +++G + + P+ + I V D+NDN P FT+ ++ V+E + PGT+V V
Sbjct: 226 ATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVT 285
Query: 267 ATDRDEP-DTMHTRLKYSILQQTPRSP--GLFSVHPSTGVITTVSHYLDREVVDKYSLIM 323
ATD D+ +T + + Y+IL Q P P +F+++ +TGVI+ V+ LDRE Y+L++
Sbjct: 286 ATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVV 345
Query: 324 KVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKDL 383
+ D+ G+ GL T+T +ITVTD+NDN P F Y+ V EN NV I + + D D
Sbjct: 346 QAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADA 403
Query: 384 INTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPF 443
NT W +TIL ++ G F ++T+ N+G+L K L++E +Q L + V N PF
Sbjct: 404 PNTPAWEAVYTIL-NDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPF 462
Query: 444 ARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNG 503
+ T A VTV V D++E P P + V + E+ VG +I Y A +P+
Sbjct: 463 EVSLTTST----ATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFME 518
Query: 504 NGLRYKKLHDPKGWITIDEISGSIITSKILDRE-VETPKNELYNITVLAIDKDD--RSCT 560
+ Y+ D W+ I+ +G+I T LDRE E KN Y ++A D + T
Sbjct: 519 QKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGT 578
Query: 561 GTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEIS 620
GTL + + DVNDN P + C+ I +D D P + +PF L + + S
Sbjct: 579 GTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGA---S 635
Query: 621 RLWSLTKVNDTAARLSYQKNAGFQ--EYTIPITVKDRAGQAATKLLRVNLCECTHPTQCR 678
W++ + T + + + +Y I + + D + L V++C+C
Sbjct: 636 ANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVC 695
Query: 679 ATSRSTGVILGKWAILAILLGI-ALLFSVLLTLVCGVFGATKGKRF--PEDLAQQNLIIS 735
++ L AIL IL GI ALL +LL L+ A + PED + N+
Sbjct: 696 RKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYY 755
Query: 736 NTEAPGDD 743
+ E G++
Sbjct: 756 DEEGGGEE 763
>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
Length = 1118
Score = 320 bits (821), Expect = 3e-87
Identities = 211/686 (30%), Positives = 338/686 (49%), Gaps = 11/686 (1%)
Query: 130 LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQN--YTVFYSISGRGVDKEPLNLFY 187
L R KR W P +++E + ++ SD A+ + Y +G+G+ + P +F
Sbjct: 44 LVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFV 103
Query: 188 IERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAI 247
+DTG L T +DREE F L YA A G + + PL L I+V D NDN PVFT+ +
Sbjct: 104 FNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDV 163
Query: 248 YNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTV 307
+ V E S T V + ATD DEP+T+++++ Y I+ P P +F ++ TG I T
Sbjct: 164 FVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTT 223
Query: 308 SHYLDREVVDKYSLIMKVQDMDGQFFGL-IGTSTCIITVTDSNDNAPTFRQNAYEAFVEE 366
S LDRE Y+L ++ +D +G+ + + I + D NDN P E VEE
Sbjct: 224 SVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEE 283
Query: 367 NAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYE 426
N NVE+ RI + D D I + NW NFT GNE G+F I TD +TNEG+++++K ++YE
Sbjct: 284 NQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYE 343
Query: 427 ENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAV 486
E + ++ + V N+A F + I + V V+++ EG + + + E++
Sbjct: 344 EMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDR 403
Query: 487 GSK---INGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNE 543
SK I ++A+D + RY KL D WI++D ++ I +K+ D E +N
Sbjct: 404 SSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNG 463
Query: 544 LYNITVLAIDKD--DRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDE 601
Y + ++AI +D ++ TGT+ +N+ED+NDN P +++ IC Y ++ A D D
Sbjct: 464 TYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICH-DAEYVNVTAEDLDG 522
Query: 602 PVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSY-QKNAGFQEYTIPITVKDRAGQAA 660
+ PF FS+ + P ++ W + + T+ L +K G E I+
Sbjct: 523 HPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKLGRSEIQFLISDNQGFSCPE 582
Query: 661 TKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSV-LLTLVCGVFGATK 719
++L + +CEC H + CR + V LG AI ++L LL V LL L+C K
Sbjct: 583 KQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMCHCGKGAK 642
Query: 720 GKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETI 779
G + +N AP +D+V + + Q + + G M G +
Sbjct: 643 GFTPIPGTIEMLHPWNNEGAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSA 702
Query: 780 EMMKGGNQTLESCRGAGHHHTLDSCR 805
++KG ++ E H +L S R
Sbjct: 703 SIVKGQHEMSEMDGRWEEHRSLLSGR 728
>gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]
Length = 1059
Score = 310 bits (794), Expect = 4e-84
Identities = 196/619 (31%), Positives = 308/619 (49%), Gaps = 35/619 (5%)
Query: 125 TRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLN 184
T+ +RR KR W + +E + ++ SD N + Y ISG G+D+ P
Sbjct: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98
Query: 185 LFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFT 244
+F I TG + T VDRE +F + A + G + PL L ++V D NDN PVF+
Sbjct: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158
Query: 245 EAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVI 304
+++Y + E+S T V +CATD DE + +++++ Y I+ Q P +F ++ TG +
Sbjct: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218
Query: 305 TTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFV 364
T+S +LDRE Y+L+++ D DG GL C I V D NDN PT + +Y A +
Sbjct: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278
Query: 365 EENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLN 424
EEN + E++R+ D D T NW + IL GN+ F I TD +TNEG+L VVK L+
Sbjct: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338
Query: 425 YEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENL 484
YE+ + L IGV N+A F + ++ V + V D+ EGP P+ ++E +
Sbjct: 339 YEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGI 398
Query: 485 AVGSKIN----GYKAYDPENRN-GNGLRYKKLHDPKGWITIDEISGSIITSKILDREVET 539
S +N Y A D + N +RY HD W+ ID +G I S+ D++ +
Sbjct: 399 KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKY 458
Query: 540 PKNELYNITVLAIDK-DDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVD 598
N +Y +LAID ++ TGT+ + + D+ND P I E IC + + +
Sbjct: 459 IINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICID----SPSVLIS 514
Query: 599 PDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQ 658
+E +G+PF F + + P I+ +W + N T+A L+ ++ Y IPI VKD +
Sbjct: 515 VNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNR 574
Query: 659 AA--TKLLRVNLCECTHPTQCRATSRS----------------------TGVILGKWAIL 694
A +++++ C+C C + + + V LG I
Sbjct: 575 ACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIG 634
Query: 695 AILLGIALL-FSVLLTLVC 712
++LGI LL + LL L+C
Sbjct: 635 MMVLGILLLILAPLLLLLC 653
>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
Length = 1040
Score = 310 bits (794), Expect = 4e-84
Identities = 196/619 (31%), Positives = 308/619 (49%), Gaps = 35/619 (5%)
Query: 125 TRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLN 184
T+ +RR KR W + +E + ++ SD N + Y ISG G+D+ P
Sbjct: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98
Query: 185 LFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFT 244
+F I TG + T VDRE +F + A + G + PL L ++V D NDN PVF+
Sbjct: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158
Query: 245 EAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVI 304
+++Y + E+S T V +CATD DE + +++++ Y I+ Q P +F ++ TG +
Sbjct: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218
Query: 305 TTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFV 364
T+S +LDRE Y+L+++ D DG GL C I V D NDN PT + +Y A +
Sbjct: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278
Query: 365 EENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLN 424
EEN + E++R+ D D T NW + IL GN+ F I TD +TNEG+L VVK L+
Sbjct: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338
Query: 425 YEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENL 484
YE+ + L IGV N+A F + ++ V + V D+ EGP P+ ++E +
Sbjct: 339 YEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGI 398
Query: 485 AVGSKIN----GYKAYDPENRN-GNGLRYKKLHDPKGWITIDEISGSIITSKILDREVET 539
S +N Y A D + N +RY HD W+ ID +G I S+ D++ +
Sbjct: 399 KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKY 458
Query: 540 PKNELYNITVLAIDK-DDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVD 598
N +Y +LAID ++ TGT+ + + D+ND P I E IC + + +
Sbjct: 459 IINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICID----SPSVLIS 514
Query: 599 PDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQ 658
+E +G+PF F + + P I+ +W + N T+A L+ ++ Y IPI VKD +
Sbjct: 515 VNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNR 574
Query: 659 AA--TKLLRVNLCECTHPTQCRATSRS----------------------TGVILGKWAIL 694
A +++++ C+C C + + + V LG I
Sbjct: 575 ACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIG 634
Query: 695 AILLGIALL-FSVLLTLVC 712
++LGI LL + LL L+C
Sbjct: 635 MMVLGILLLILAPLLLLLC 653
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 289 bits (739), Expect = 9e-78
Identities = 199/642 (30%), Positives = 321/642 (50%), Gaps = 32/642 (4%)
Query: 122 TRHTRETV---LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGV 178
T+ T+E + LRR+KRRW ++E GPFP + ++ ++ + N ++ Y ISG GV
Sbjct: 38 TKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGV 97
Query: 179 DKEP-LNLFYIE-RDTGNLFCTRPVDRE---EYDVFDLIAYASTADGYSADLPLPLPIRV 233
D+ P + LF +E + G ++ RPVDRE + V+ + ST G D L IR+
Sbjct: 98 DEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERST--GKIVDTSLIFNIRI 155
Query: 234 EDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTP--RS 291
D ND+ P F E +N V E+ G + + A D DE +T ++++ Y ++ QTP +
Sbjct: 156 SDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKE 215
Query: 292 PGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDN 351
G F V +G I +S LD E +++L+++ +D L T+T + V + N++
Sbjct: 216 SG-FRVDRLSGEIR-LSGCLDYETAPQFTLLIRARDCGEP--SLSSTTTVHVDVQEGNNH 271
Query: 352 APTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKE 411
P F Q Y+ + E + +LR+ ++D+D T+ WR F IL GNE GHF ISTD E
Sbjct: 272 RPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPE 331
Query: 412 TNEGVLSVVKPLNYEENRQVNLEIGVNNEAPF-----ARDIPRVTALNRALVTVHVRDLD 466
TNEG+L+V+KPL+YE +L I V NE + P A A V+V V D +
Sbjct: 332 TNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDAN 391
Query: 467 EGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGS 526
+ P P + V +E G+ + + A DP+++ +RY+ +HDP W+++D+ SG
Sbjct: 392 DPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPDSQ----IRYELVHDPANWVSVDKNSGV 447
Query: 527 IITSKILDREVETPKNELYNITVLAIDK--DDRSCTGTLAVNIEDVNDNPPEI--LQEYV 582
+IT + +DRE N Y I + A+D ++ TGTL + + D+NDN P + Y+
Sbjct: 448 VITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYM 507
Query: 583 VICKPKMGY-TDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNA 641
+C+ + I A DPD PF F L NT W L + + L ++
Sbjct: 508 EVCESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLRSL 567
Query: 642 GFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQC-RATSRSTGVILGK-WAILAILLG 699
Y +P+ + D+ G + + + V +C C C G+ +G + + A +
Sbjct: 568 PRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGLTCVELADAEVGLHVGALFPVCAAFVA 627
Query: 700 IALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPG 741
+A+ LL + G D Q L++ N E+ G
Sbjct: 628 LAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKG 669
>gi|119964718 desmoglein 3 preproprotein [Homo sapiens]
Length = 999
Score = 285 bits (730), Expect = 9e-77
Identities = 214/743 (28%), Positives = 346/743 (46%), Gaps = 86/743 (11%)
Query: 113 LEHQKKVSKTRHTRETVLRRAKRRWAPI--PCSMQENSLGPFPLFLQQVESDAAQNYTVF 170
+E + + + T + RR KR W PC E++ P+ ++ SD +
Sbjct: 27 IETKGQYDEEEMTMQQAKRRQKREWVKFAKPCREGEDNSKRNPI--AKITSDYQATQKIT 84
Query: 171 YSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLP 230
Y ISG G+D+ P +F ++++TG++ T VDREE F + A A G + PL L
Sbjct: 85 YRISGVGIDQPPFGIFVVDKNTGDINITAIVDREETPSFLITCRALNAQGLDVEKPLILT 144
Query: 231 IRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPR 290
+++ D NDN PVF++ I+ E+ E+S + V ++ ATD DEP+ +++++ + I+ Q P
Sbjct: 145 VKILDINDNPPVFSQQIFMGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIVSQEPA 204
Query: 291 SPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSND 350
+F + +TG + T+++ LDRE Y L++ D DG+ GL C I V D ND
Sbjct: 205 GTPMFLLSRNTGEVRTLTNSLDREQASSYRLVVSGADKDGE--GLSTQCECNIKVKDVND 262
Query: 351 NAPTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDK 410
N P FR + Y A +EEN + E+LR + D D T NW + GNE F+I TD
Sbjct: 263 NFPMFRDSQYSARIEENILSSELLRFQVTDLDEEYTDNWLAVYFFTSGNEGNWFEIQTDP 322
Query: 411 ETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPE 470
TNEG+L VVK L+YE+ + V L I V N+A F + + + VT+ V ++ EG
Sbjct: 323 RTNEGILKVVKALDYEQLQSVKLSIAVKNKAEFHQSVISRYRVQSTPVTIQVINVREGIA 382
Query: 471 CTPAAQYVRIKENLA----VGSKINGYKAYDPE-NRNGNGLRYKKLHDPKGWITIDEISG 525
PA++ +++ ++ V + Y+A D + N+ + ++Y + G++ ID +
Sbjct: 383 FRPASKTFTVQKGISSKKLVDYILGTYQAIDEDTNKAASNVKYVMGRNDGGYLMIDSKTA 442
Query: 526 SIITSKILDREVETPKNELYNITVLAIDK-DDRSCTGTLAVNIEDVNDNPPEILQEYVVI 584
I K ++R+ N+ VLAID+ ++ TGT+ V + D NDN P + E +
Sbjct: 443 EIKFVKNMNRDSTFIVNKTITAEVLAIDEYTGKTSTGTVYVRVPDFNDNCPTAVLEKDAV 502
Query: 585 CKPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQ 644
C +++ + P+ F+L + ++ +WS+T +N T+A L Q+
Sbjct: 503 CSSSPSV--VVSARTLNNRYTGPYTFALEDQPVKLPAVWSITTLNATSALLRAQEQIPPG 560
Query: 645 EYTIPITVKDRAGQAA--TKLLRVNLCEC--------THPTQCRAT--SRSTGVILGKWA 692
Y I + + D + L + +C+C ++PT T R LG A
Sbjct: 561 VYHISLVLTDSQNNRCEMPRSLTLEVCQCDNRGICGTSYPTTSPGTRYGRPHSGRLGPAA 620
Query: 693 ILAILLGIALLF---SVLLTLVCGVFGATKG----------------------KRFPEDL 727
I +LLG+ LL +LLT CG G+T G PED
Sbjct: 621 IGLLLLGLLLLLLAPLLLLTCDCGA-GSTGGVTGGFIPVPDGSEGTIHQWGIEGAHPEDK 679
Query: 728 AQQNLIISNTEAPGDD-----RVCS-----------------------------ANGFMT 753
N+ + A G D VC+ A GF T
Sbjct: 680 EITNICVPPVTANGADFMESSEVCTNTYARGTAVEGTSGMEMTTKLGAATESGGAAGFAT 739
Query: 754 QTTNNSSQGFCGTMGSGMKNGGQ 776
T + ++ GF G G+ + GQ
Sbjct: 740 GTVSGAASGFGAATGVGICSSGQ 762
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 262 bits (670), Expect = 9e-70
Identities = 209/648 (32%), Positives = 335/648 (51%), Gaps = 41/648 (6%)
Query: 120 SKTRHTR-ET-VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYSISGR 176
++T+H ET V R KR W + E +GP P ++ ++ S++ + + +V Y ++G
Sbjct: 36 NQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGE 95
Query: 177 GVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRVED 235
G +F I+ TG++ T+ +DRE+ + L A A + I+V+D
Sbjct: 96 GAG----TIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQD 151
Query: 236 ENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGL 294
NDN P FT+ Y V E S GT+V V ATD D+P ++ R+ YSILQ P
Sbjct: 152 INDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP----Y 207
Query: 295 FSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPT 354
FSV P TGVI T H +DRE + YS++++ +DM GQ GL G++T IT+TD NDN P
Sbjct: 208 FSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPR 267
Query: 355 FRQNAYEAFVEENA-FNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETN 413
F Q Y+ +V E+A + +I D D + A+ + ++I+ G+ G F ISTDKET
Sbjct: 268 FPQKHYQLYVPESAQVGSAVGKIKANDADTGSNAD--MTYSIINGDGMGIFSISTDKETR 325
Query: 414 EGVLSVVKPLNYEENRQVNLEI-GVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECT 472
EG+LS+ KPLNYE+ + L I G N F R + ++ + V D+DE P +
Sbjct: 326 EGILSLKKPLNYEKKKSYTLNIEGANTHLDF-RFSHLGPFKDATMLKIIVGDVDEPPLFS 384
Query: 473 PAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRY---KKLHDPKGWITIDEISGSIIT 529
+ + + EN +G+ + A DP++ N + +RY + D + + ID +G+I T
Sbjct: 385 MPSYLMEVYENAKIGTVVGTVLAQDPDSTN-SLVRYFINYNVEDDR-FFNIDANTGTIRT 442
Query: 530 SKILDREVETPKNELYNITVLA--IDKDDRSCTGTLAVNIEDVNDNPPEILQEY-VVIC- 585
+K+LDRE ETP YNITV A ID D T+ + + DVNDNPPE+ +EY +++C
Sbjct: 443 TKVLDRE-ETP---WYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCE 498
Query: 586 --KPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAG- 642
KP I A D D+ +G F F L P ++TA+ L+ ++
Sbjct: 499 NSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSR 558
Query: 643 --FQEYTIPITVKDRA--GQAATKLLRVNLCECTHPTQ---CRATSRSTGVILGKWAILA 695
Y +PI + D +++ L + +C C + C A + + L A++A
Sbjct: 559 TVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIA 618
Query: 696 ILLGIALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPGDD 743
ILL + +L ++++ + + E+ ++N++ + E G++
Sbjct: 619 ILLCVLILLAIVVLFITLRRSKKEPLIISEEDVRENVVTYDDEGGGEE 666
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 261 bits (668), Expect = 1e-69
Identities = 200/602 (33%), Positives = 307/602 (50%), Gaps = 39/602 (6%)
Query: 132 RAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYSISGRGVDKEPLNLFYIER 190
R KR W + E +G PL++ ++ SD + + ++ Y +SG G ++F I+
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGAS----SIFIIDE 99
Query: 191 DTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRVEDENDNHPVFTEAIYN 249
+TG++ T+ +DREE + L A A + I+++D NDN P F + Y
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 250 FEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGLFSVHPSTGVITTVS 308
V E S GT+V V ATD D+P ++ R+ YSILQ P FSV P TGVI T
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP----YFSVEPKTGVIKTAL 215
Query: 309 HYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENA 368
+DRE D+Y L+++ +DM GQ GL GT++ +T+TD NDN P F + +Y+ V E+
Sbjct: 216 PNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESL 275
Query: 369 FNVEIL-RIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEE 427
++ RI D D+ AN + + I+ G+ G FKIS DKET EG++++ K L++E
Sbjct: 276 PVASVVARIKAADADI--GANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEA 333
Query: 428 NRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVG 487
L I N+ R + + V + V D+DE P + + + E VG
Sbjct: 334 KTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVG 393
Query: 488 SKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSIITSKILDREVETPKNELY 545
+ I A+DP++ N + +RY + D + + ID SG I T+K LDRE N ++
Sbjct: 394 NIIGTVAAHDPDSSN-SPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET----NAIH 448
Query: 546 NITVLAIDKDDRSCTGT--LAVNIEDVNDNPPEILQEY-VVIC---KPKMGYTDILAVDP 599
NITVLA++ + S G +A+ I D+NDN PE +Y +C +P I AVD
Sbjct: 449 NITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDK 508
Query: 600 DEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQE-----YTIPITVKD 654
DEP +G FYFSL T + +SL D A + ++N GF+ Y +PI + D
Sbjct: 509 DEPSNGHQFYFSL-TTDATNNHNFSLKDNKDNTASILTRRN-GFRRQEQSVYYLPIFIVD 566
Query: 655 RAGQ--AATKLLRVNLCECTH---PTQCRATSRSTGVILGKWAILAILLGIALLFSVLLT 709
++T L + +C+C C A + L A++AIL + L ++L
Sbjct: 567 SGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILL 626
Query: 710 LV 711
+V
Sbjct: 627 IV 628
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 261 bits (668), Expect = 1e-69
Identities = 200/602 (33%), Positives = 307/602 (50%), Gaps = 39/602 (6%)
Query: 132 RAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYSISGRGVDKEPLNLFYIER 190
R KR W + E +G PL++ ++ SD + + ++ Y +SG G ++F I+
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGAS----SIFIIDE 99
Query: 191 DTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRVEDENDNHPVFTEAIYN 249
+TG++ T+ +DREE + L A A + I+++D NDN P F + Y
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 250 FEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGLFSVHPSTGVITTVS 308
V E S GT+V V ATD D+P ++ R+ YSILQ P FSV P TGVI T
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP----YFSVEPKTGVIKTAL 215
Query: 309 HYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENA 368
+DRE D+Y L+++ +DM GQ GL GT++ +T+TD NDN P F + +Y+ V E+
Sbjct: 216 PNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESL 275
Query: 369 FNVEIL-RIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEE 427
++ RI D D+ AN + + I+ G+ G FKIS DKET EG++++ K L++E
Sbjct: 276 PVASVVARIKAADADI--GANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEA 333
Query: 428 NRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVG 487
L I N+ R + + V + V D+DE P + + + E VG
Sbjct: 334 KTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVG 393
Query: 488 SKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSIITSKILDREVETPKNELY 545
+ I A+DP++ N + +RY + D + + ID SG I T+K LDRE N ++
Sbjct: 394 NIIGTVAAHDPDSSN-SPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET----NAIH 448
Query: 546 NITVLAIDKDDRSCTGT--LAVNIEDVNDNPPEILQEY-VVIC---KPKMGYTDILAVDP 599
NITVLA++ + S G +A+ I D+NDN PE +Y +C +P I AVD
Sbjct: 449 NITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDK 508
Query: 600 DEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQE-----YTIPITVKD 654
DEP +G FYFSL T + +SL D A + ++N GF+ Y +PI + D
Sbjct: 509 DEPSNGHQFYFSL-TTDATNNHNFSLKDNKDNTASILTRRN-GFRRQEQSVYYLPIFIVD 566
Query: 655 RAGQ--AATKLLRVNLCECTH---PTQCRATSRSTGVILGKWAILAILLGIALLFSVLLT 709
++T L + +C+C C A + L A++AIL + L ++L
Sbjct: 567 SGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILL 626
Query: 710 LV 711
+V
Sbjct: 627 IV 628
>gi|119703744 desmoglein 1 preproprotein [Homo sapiens]
Length = 1049
Score = 253 bits (646), Expect = 5e-67
Identities = 144/446 (32%), Positives = 235/446 (52%), Gaps = 2/446 (0%)
Query: 130 LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIE 189
+RR KR W + +E + ++ SD A N V Y ISG G+D+ P +F I
Sbjct: 44 IRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVIN 103
Query: 190 RDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYN 249
+ TG + T VDRE F + A + G + PL L +RV D NDN PVF+ A +
Sbjct: 104 QKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFA 163
Query: 250 FEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTVSH 309
++ E+S T V ++ ATD DEP+ +++++ + I++Q P +F ++ +TG I T+++
Sbjct: 164 GQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNN 223
Query: 310 YLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAF 369
+LDRE +Y+L ++ D DG G+ C I + D NDN P Q++Y ++EN
Sbjct: 224 FLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTL 283
Query: 370 NVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENR 429
N +L I + D D +ANW + GNE F+I ++ TN G+L VVKPL+YE +
Sbjct: 284 NSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQ 343
Query: 430 QVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSK 489
+ L IGV N+A F I L + ++V V ++ EGP P ++ + N+ K
Sbjct: 344 SLQLSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDK 403
Query: 490 INGYKAYDPE-NRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNIT 548
+ + A D + R +RY ++P + +D +G + + +E Y T
Sbjct: 404 VGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGT 463
Query: 549 VLAIDKD-DRSCTGTLAVNIEDVNDN 573
+L+ID + R+CTGT+ +NI+ ++
Sbjct: 464 ILSIDDNLQRTCTGTININIQSFGND 489
Score = 33.1 bits (74), Expect = 1.1
Identities = 40/166 (24%), Positives = 69/166 (41%), Gaps = 14/166 (8%)
Query: 514 PKGWITIDEISGSIITSKILDREVETPKNELYNITVLAIDKD-DRSCTGTLAVNIEDVND 572
P G I++ +G I + I+DREV TP +Y + ++ +D +R L V + D+ND
Sbjct: 96 PYGIFVINQKTGEINITSIVDREV-TPFFIIYCRALNSMGQDLERPLE--LRVRVLDIND 152
Query: 573 NPPEILQEYVVICKPKMGYTDIL-----AVDPDEPVH-GAPFYFSLPNTSPEISRLWSLT 626
NPP + + L A D DEP + + F + P S ++ +
Sbjct: 153 NPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIIN 212
Query: 627 K-VNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKLLRVNLCEC 671
+ + ++ + +Y + + DR G A CEC
Sbjct: 213 RNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAE---CEC 255
>gi|221316595 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 246 bits (629), Expect = 5e-65
Identities = 182/601 (30%), Positives = 286/601 (47%), Gaps = 42/601 (6%)
Query: 138 APIPCSMQENSLGPFPLFLQQVE-SDAAQNYTVFYSISGRGVDKEPLNLFYIERDT-GNL 195
AP P M ENS P P+ + QV +D Y++ VDKE L F D G++
Sbjct: 241 APKPVEMVENSTDPHPIKITQVRWNDPGAQYSL--------VDKEKLPRFPFSIDQEGDI 292
Query: 196 FCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLES 255
+ T+P+DREE D + A A G PL + ++V+D NDN P + FEV E+
Sbjct: 293 YVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFEVQEN 352
Query: 256 SRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSP--GLFSVHPSTGVITTVSHYLDR 313
R G ++G + A DRDE +T ++ L Y I++QTP+ P GLF + G++ L +
Sbjct: 353 ERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLKK 412
Query: 314 EVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYE--AFVEENAFNV 371
+ +Y+L ++V D D + + I V D ND P F ++ Y E+
Sbjct: 413 QDTPQYNLTIEVSDKDFKTLCFVQ-----INVIDINDQIPIFEKSDYGNLTLAEDTNIGS 467
Query: 372 EILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQV 431
IL I D D T + ++ + I+KG+ G + TD TN G + + KPL++E
Sbjct: 468 TILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAVS 527
Query: 432 NLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKIN 491
N+ N P + + A + A T+ V D++E P+ + ++ E++A+G+K+
Sbjct: 528 NIVFKAENPEPLVFGV-KYNASSFAKFTLIVTDVNEAPQFSQHVFQAKVSEDVAIGTKVG 586
Query: 492 GYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLA 551
A DPE G + Y D +GW+ ID ++G I + LDRE +P Y + V+A
Sbjct: 587 NVTAKDPE---GLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREAGSP----YRVQVVA 639
Query: 552 IDKDDRSCTGTLAVN--IEDVNDNPPEILQEY--VVICKPKMGYTDILAVDPDEPVH--- 604
+ S + + + DVNDNPP + ++Y + C P ++ D+ H
Sbjct: 640 TEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQHLFR 699
Query: 605 GAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQ--EYTIPITVKD--RAGQAA 660
G F FSL + S + W ++K+N T ARLS ++ F+ EY + I + D R
Sbjct: 700 GPHFTFSLGSGS--LQNDWEVSKINGTHARLS-TRHTEFEEREYVVLIRINDGGRPPLEG 756
Query: 661 TKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKG 720
L V C C + R TG+ A+ ILL L+ ++L +V KG
Sbjct: 757 IVSLPVTFCSCVEGSCFRPAGHQTGIPTVGMAV-GILLTTLLVIGIILAVVFIRIKKDKG 815
Query: 721 K 721
K
Sbjct: 816 K 816
Score = 117 bits (294), Expect = 3e-26
Identities = 122/446 (27%), Positives = 202/446 (45%), Gaps = 52/446 (11%)
Query: 184 NLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVF 243
N+F IER+ G L+ R +DRE +L A A+G + P+P+ I+V+D NDN P F
Sbjct: 68 NIFVIERE-GLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDINDNRPTF 126
Query: 244 TEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGL--FSVHPST 301
++ Y V ++SRPG V ATD D+P T + +L Y I+ Q P + F ++ T
Sbjct: 127 LQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQINNKT 186
Query: 302 GVITTV---SHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCI-ITVTDSNDNAPTFRQ 357
G I+ S L+ Y+L++ V+DM GQ +T + I VT++ AP
Sbjct: 187 GAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKAPK--- 243
Query: 358 NAYEAFVEENAFNVEILRIPIEDKDLINTANWR---VNFTILKGNENGHFKISTDKETNE 414
+ EN+ + ++ I W ++++ + F S D+ E
Sbjct: 244 ---PVEMVENSTDPHPIK--------ITQVRWNDPGAQYSLVDKEKLPRFPFSIDQ---E 289
Query: 415 GVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPA 474
G + V +PL+ EE +E P + V V+D+++ P P+
Sbjct: 290 GDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYP-------LEIHVKVKDINDNPPTCPS 342
Query: 475 AQYV-RIKENLAVGSKINGYKAY--DPENRNGNGLRYKKLHD-PK----GWITIDEISGS 526
V ++EN +G+ I A+ D EN + L Y+ + PK G I +G
Sbjct: 343 PVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAGM 402
Query: 527 IITSKILDREVETPKNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQ----EYV 582
+ +K ++ +TP+ YN+T+ DKD ++ + +N+ D+ND P +
Sbjct: 403 LQLAKQSLKKQDTPQ---YNLTIEVSDKDFKTLC-FVQINVIDINDQIPIFEKSDYGNLT 458
Query: 583 VICKPKMGYT--DILAVDPDEPVHGA 606
+ +G T I A D DEP G+
Sbjct: 459 LAEDTNIGSTILTIQATDADEPFTGS 484
>gi|221316593 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 246 bits (629), Expect = 5e-65
Identities = 182/601 (30%), Positives = 286/601 (47%), Gaps = 42/601 (6%)
Query: 138 APIPCSMQENSLGPFPLFLQQVE-SDAAQNYTVFYSISGRGVDKEPLNLFYIERDT-GNL 195
AP P M ENS P P+ + QV +D Y++ VDKE L F D G++
Sbjct: 241 APKPVEMVENSTDPHPIKITQVRWNDPGAQYSL--------VDKEKLPRFPFSIDQEGDI 292
Query: 196 FCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLES 255
+ T+P+DREE D + A A G PL + ++V+D NDN P + FEV E+
Sbjct: 293 YVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFEVQEN 352
Query: 256 SRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSP--GLFSVHPSTGVITTVSHYLDR 313
R G ++G + A DRDE +T ++ L Y I++QTP+ P GLF + G++ L +
Sbjct: 353 ERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLKK 412
Query: 314 EVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYE--AFVEENAFNV 371
+ +Y+L ++V D D + + I V D ND P F ++ Y E+
Sbjct: 413 QDTPQYNLTIEVSDKDFKTLCFVQ-----INVIDINDQIPIFEKSDYGNLTLAEDTNIGS 467
Query: 372 EILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQV 431
IL I D D T + ++ + I+KG+ G + TD TN G + + KPL++E
Sbjct: 468 TILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAVS 527
Query: 432 NLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKIN 491
N+ N P + + A + A T+ V D++E P+ + ++ E++A+G+K+
Sbjct: 528 NIVFKAENPEPLVFGV-KYNASSFAKFTLIVTDVNEAPQFSQHVFQAKVSEDVAIGTKVG 586
Query: 492 GYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLA 551
A DPE G + Y D +GW+ ID ++G I + LDRE +P Y + V+A
Sbjct: 587 NVTAKDPE---GLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREAGSP----YRVQVVA 639
Query: 552 IDKDDRSCTGTLAVN--IEDVNDNPPEILQEY--VVICKPKMGYTDILAVDPDEPVH--- 604
+ S + + + DVNDNPP + ++Y + C P ++ D+ H
Sbjct: 640 TEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQHLFR 699
Query: 605 GAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQ--EYTIPITVKD--RAGQAA 660
G F FSL + S + W ++K+N T ARLS ++ F+ EY + I + D R
Sbjct: 700 GPHFTFSLGSGS--LQNDWEVSKINGTHARLS-TRHTEFEEREYVVLIRINDGGRPPLEG 756
Query: 661 TKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKG 720
L V C C + R TG+ A+ ILL L+ ++L +V KG
Sbjct: 757 IVSLPVTFCSCVEGSCFRPAGHQTGIPTVGMAV-GILLTTLLVIGIILAVVFIRIKKDKG 815
Query: 721 K 721
K
Sbjct: 816 K 816
Score = 117 bits (294), Expect = 3e-26
Identities = 122/446 (27%), Positives = 202/446 (45%), Gaps = 52/446 (11%)
Query: 184 NLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVF 243
N+F IER+ G L+ R +DRE +L A A+G + P+P+ I+V+D NDN P F
Sbjct: 68 NIFVIERE-GLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDINDNRPTF 126
Query: 244 TEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGL--FSVHPST 301
++ Y V ++SRPG V ATD D+P T + +L Y I+ Q P + F ++ T
Sbjct: 127 LQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQINNKT 186
Query: 302 GVITTV---SHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCI-ITVTDSNDNAPTFRQ 357
G I+ S L+ Y+L++ V+DM GQ +T + I VT++ AP
Sbjct: 187 GAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKAPK--- 243
Query: 358 NAYEAFVEENAFNVEILRIPIEDKDLINTANWR---VNFTILKGNENGHFKISTDKETNE 414
+ EN+ + ++ I W ++++ + F S D+ E
Sbjct: 244 ---PVEMVENSTDPHPIK--------ITQVRWNDPGAQYSLVDKEKLPRFPFSIDQ---E 289
Query: 415 GVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPA 474
G + V +PL+ EE +E P + V V+D+++ P P+
Sbjct: 290 GDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYP-------LEIHVKVKDINDNPPTCPS 342
Query: 475 AQYV-RIKENLAVGSKINGYKAY--DPENRNGNGLRYKKLHD-PK----GWITIDEISGS 526
V ++EN +G+ I A+ D EN + L Y+ + PK G I +G
Sbjct: 343 PVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAGM 402
Query: 527 IITSKILDREVETPKNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQ----EYV 582
+ +K ++ +TP+ YN+T+ DKD ++ + +N+ D+ND P +
Sbjct: 403 LQLAKQSLKKQDTPQ---YNLTIEVSDKDFKTLC-FVQINVIDINDQIPIFEKSDYGNLT 458
Query: 583 VICKPKMGYT--DILAVDPDEPVHGA 606
+ +G T I A D DEP G+
Sbjct: 459 LAEDTNIGSTILTIQATDADEPFTGS 484
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 244 bits (622), Expect = 3e-64
Identities = 204/642 (31%), Positives = 328/642 (51%), Gaps = 52/642 (8%)
Query: 131 RRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYSISGRGVDKEPLNLFYIE 189
+R KR W + E G PL++ ++ SD + + ++ Y +SG G +F I+
Sbjct: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI----VFTID 110
Query: 190 RDTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRVEDENDNHPVFTEAIY 248
TG++ + +DREE + L A A G + I+++D NDN P F + Y
Sbjct: 111 DTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPY 170
Query: 249 NFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGLFSVHPSTGVITTV 307
V E S GT+V V ATD D+P ++ R+ YSILQ P FSV TGVI T
Sbjct: 171 VATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQP----YFSVDSKTGVIRTA 226
Query: 308 SHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEEN 367
+DRE + Y +I++ +DM GQ GL GT+T IT++D NDN P F Q Y+ V E+
Sbjct: 227 LMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLES 286
Query: 368 AFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEE 427
A + + KDL N + +TI+ G+ F ISTD G+++V KPL++E
Sbjct: 287 A-PISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFES 345
Query: 428 NRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVG 487
+ L++ N R + + V + V D+DE P P +V + E++A+G
Sbjct: 346 KKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIG 405
Query: 488 SKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSIITSKILDREVETPKNELY 545
+ I A DP+ N N +RY + DP + +D +G+++T++ LDRE + +
Sbjct: 406 TTIQIISAKDPDVTN-NSIRYSIDRSSDPGRFFYVDITTGALMTARPLDRE----EFSWH 460
Query: 546 NITVLAIDKDDRSCTGTLAVNIE--DVNDNPPEILQEY-VVICK-PKMG--YTDILAVDP 599
NITVLA++ ++ S G++ V I+ DVNDN PE + Y +C+ K G + AVD
Sbjct: 461 NITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAFVCENAKAGQLIQTVSAVDQ 520
Query: 600 DEPVHGAPFYFSLPNTSPEISR--LWSLTKVNDTAARLSYQKNAGFQE-----YTIPITV 652
D+P +G FY+SL +PE + +++ D AR+ + +GF++ + +PI +
Sbjct: 521 DDPRNGQHFYYSL---APEAANNPNFTIRDNQDNTARI-LTRRSGFRQQEQSVFHLPILI 576
Query: 653 KDRAGQ---AATKLLRVNLCECT---HPTQCRATSRSTGVILGKWAILAILLGIALLFSV 706
D +GQ ++T L + +C C H C + V L + A++AIL A +F V
Sbjct: 577 AD-SGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAIL---ACIF-V 631
Query: 707 LLTLVCGVFGATKGKRFP-----EDLAQQNLIISNTEAPGDD 743
LL LV + + ++ P E+ +N++ + E G++
Sbjct: 632 LLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEE 673
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 243 bits (619), Expect = 7e-64
Identities = 205/658 (31%), Positives = 322/658 (48%), Gaps = 55/658 (8%)
Query: 116 QKKVSKTRHTRET--VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYS 172
Q+++ +R R +L R KR W + E G ++ ++ SD + + ++ Y
Sbjct: 33 QQRILSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYI 92
Query: 173 ISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLP-LPLPI 231
+SG G LF I+ TG++ TR +DREE + L A A P I
Sbjct: 93 LSGDGAG----TLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVI 148
Query: 232 RVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPR 290
++ D NDN P F E IY V E S GT+V V ATD D+P ++ R+ YSILQ P
Sbjct: 149 KIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP- 207
Query: 291 SPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSND 350
FSV P TG+I T ++RE ++Y ++++ +DM GQ GL GT+T IT+TD ND
Sbjct: 208 ---YFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVND 264
Query: 351 NAPTFRQNAYEAFV-EENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTD 409
N P F QN V E + I + D D N V + I+ G+ F I T+
Sbjct: 265 NPPRFPQNTIHLRVLESSPVGTAIGSVKATDAD--TGKNAEVEYRIIDGDGTDMFDIVTE 322
Query: 410 KETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGP 469
K+T EG+++V KPL+YE R L++ N R + +V + + D+DE P
Sbjct: 323 KDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPP 382
Query: 470 ECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSI 527
+ ++ + E++ VG+ I A DP++ + + +R+ + D I +GS+
Sbjct: 383 VFSRSSYLFEVHEDIEVGTIIGTVMARDPDSIS-SPIRFSLDRHTDLDRIFNIHSGNGSL 441
Query: 528 ITSKILDREVETPKNELYNITVLAIDKDDRSCTGTLA--VNIEDVNDNPPEILQEY-VVI 584
TSK LDRE+ ++ +N+TV+A + ++ T +A V I DVNDN P+ Y +
Sbjct: 442 YTSKPLDREL----SQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFV 497
Query: 585 C---KPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNA 641
C +P I AVD D+P+ G F+FSL +P +++ D AR+ +KN
Sbjct: 498 CENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPN----FTVQDNEDNTARILTRKN- 552
Query: 642 GFQE-----YTIPITVKDR--AGQAATKLLRVNLCECT---HPTQCRATSRSTGVILGKW 691
GF Y +P+ + D Q++T L + +C C + C A + L
Sbjct: 553 GFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTG 612
Query: 692 AILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDL------AQQNLIISNTEAPGDD 743
A++AILL I ++L ++ +F A K +R E L + N++ N E G++
Sbjct: 613 ALIAILLCI-----IILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEE 665
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 240 bits (612), Expect = 5e-63
Identities = 202/653 (30%), Positives = 318/653 (48%), Gaps = 44/653 (6%)
Query: 116 QKKVSKTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYSIS 174
+K+ + + L R+KR W + E G ++ ++ SD + + ++ Y +S
Sbjct: 34 KKRALELSGNSKNELNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILS 93
Query: 175 GRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRV 233
G G +LF I +TG++ T+ +DREE V+ L A A + G + I++
Sbjct: 94 GDGAG----DLFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKI 149
Query: 234 EDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSP 292
D NDN P+FT+ +Y V E S GT V V ATD D+P ++ ++ YSILQ P
Sbjct: 150 HDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQP--- 206
Query: 293 GLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNA 352
FSV TG+I T +DRE ++Y ++++ +DM GQ GL GT+T IT+TD NDN
Sbjct: 207 -YFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNP 265
Query: 353 PTFRQNAYEAFVEENA-FNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKE 411
P F Q+ Y+ E++ I RI D D+ N + ++I G F + TD+E
Sbjct: 266 PRFPQSTYQFKTPESSPPGTPIGRIKASDADV--GENAEIEYSITDGEGLDMFDVITDQE 323
Query: 412 TNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPEC 471
T EG+++V K L++E+ + L++ +N R + + A V + V D+DE P
Sbjct: 324 TQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVF 383
Query: 472 TPAAQYVRIKENLAVGSKINGYKAYDPE-NRNGNGLRYKKLHDPKGWITIDEISGSIITS 530
+ A ++I+E+ + + I A DP+ RN + D ID +GSI TS
Sbjct: 384 SKLAYILQIREDAQINTTIGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTS 443
Query: 531 KILDREVETPKNELYNITVLA--IDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPK 588
K+LDRE +NITV+A I+ +S L + + DVNDN PE + Y K
Sbjct: 444 KLLDRETLL----WHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEK 499
Query: 589 MGYTDIL----AVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQ 644
++ AVD D+P G F FSL + S ++TA L+ +
Sbjct: 500 AKADQLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRH 559
Query: 645 E---YTIPITVKDR--AGQAATKLLRVNLCECTH---PTQCRATSRSTGVILGKWAILAI 696
E Y +P+ + D Q++T + V +C C H C A + L A++AI
Sbjct: 560 EMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVAI 619
Query: 697 LLGIALLFSVLLTLVCGVFGATKGKRFPEDL------AQQNLIISNTEAPGDD 743
LL I +L L+T+V +F A + +R E L + N++ N E G++
Sbjct: 620 LLCIVIL---LVTVV--LFAALRRQRKKEPLIISKEDIRDNIVSYNDEGGGEE 667
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 234 bits (596), Expect = 3e-61
Identities = 202/651 (31%), Positives = 312/651 (47%), Gaps = 62/651 (9%)
Query: 129 VLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDA-AQNYTVFYSISGRGVDKEPLNLFY 187
VL+R+KR W + E GP P+ + ++ SD + + + Y +SG G +F
Sbjct: 47 VLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAG----TIFV 102
Query: 188 IERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLP----IRVEDENDNHPVF 243
I+ +GN+ T+ +DREE + L+A A D + PL P ++V+D NDN P F
Sbjct: 103 IDDKSGNIHATKTLDREERAQYTLMAQAVDRD---TNRPLEPPSEFIVKVQDINDNPPEF 159
Query: 244 TEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGLFSVHPSTG 302
Y+ V E S GT+V V A+D D+P ++ +L YSIL+ P FSV TG
Sbjct: 160 LHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP----YFSVEAQTG 215
Query: 303 VITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEA 362
+I T +DRE ++Y ++++ +DM G GL GT+ IT+TD NDN P F Q+ Y+
Sbjct: 216 IIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQM 275
Query: 363 FVEENAF-NVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVK 421
V E A E+ R+ +D D+ N V + I+ G+ F+I+TD ET EGV+ + K
Sbjct: 276 SVSEAAVPGEEVGRVKAKDPDI--GENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKK 333
Query: 422 PLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIK 481
P+++E R +L++ N + I + V + V D DE P + ++
Sbjct: 334 PVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQ 393
Query: 482 ENLAVGSKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSIITSKILDREVET 539
EN A G+ + A DP+ N + +RY + D + TI+ G I T+K LDRE
Sbjct: 394 ENAAAGTVVGRVHAKDPDAAN-SPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE--- 449
Query: 540 PKNELYNITVLAIDKDDR--SCTGTLAVNIEDVNDNPPEILQEYV-VIC-----KP--KM 589
+ NITV A + +R +A+ + DVNDN P+ Y IC KP
Sbjct: 450 -ETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQ 508
Query: 590 GYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLS--YQKNAGFQE-- 645
I A D D+ +G F FSLP PEI + T V D + Y + GF
Sbjct: 509 PIVTISADDKDDTANGPRFIFSLP---PEIIHNPNFT-VRDNRDNTAGVYARRGGFSRQK 564
Query: 646 ---YTIPITVKDRA--GQAATKLLRVNLCECT---HPTQCRATSRSTGVILGKWAILAIL 697
Y +PI + D ++T L + +C C C A + L A++AIL
Sbjct: 565 QDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAIL 624
Query: 698 LGIALLFSVLLTLVCGVFGATKGKR-----FPEDLAQQNLIISNTEAPGDD 743
I +L +++ V + K+ F E+ ++N+I + E G++
Sbjct: 625 ACIVILLVIVVLFVT----LRRQKKEPLIVFEEEDVRENIITYDDEGGGEE 671
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 232 bits (592), Expect = 9e-61
Identities = 187/602 (31%), Positives = 291/602 (48%), Gaps = 37/602 (6%)
Query: 132 RAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYSISGRGVDKEPLNLFYIER 190
R KR W + E G PL++ ++ SD+ + + + Y+ISG G +F I+
Sbjct: 59 RVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAG----TIFLIDE 114
Query: 191 DTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRVEDENDNHPVFTEAIYN 249
TG++ +DRE+ + L A A A + I+V+D ND+ P F Y
Sbjct: 115 LTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYI 174
Query: 250 FEVLESSRPGTTVGVVCATDRDEPDT-MHTRLKYSILQQTPRSPGLFSVHPSTGVITTVS 308
V E S GT+V V A+D D+P RL YS+L F+V P TGVI T
Sbjct: 175 GSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHH----FTVDPKTGVIRTAV 230
Query: 309 HYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENA 368
LDRE ++Y ++++ DM GQ GL G++T I VTD NDN P F Q Y+ ++E+A
Sbjct: 231 PDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESA 290
Query: 369 -FNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEE 427
+ R+ ED D+ + + + FK++TD +T E ++ V K L++E
Sbjct: 291 PIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFES 350
Query: 428 NRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVG 487
+ + N+ R T ++A+V V V D+DE PE P + + ++E+ VG
Sbjct: 351 QPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVG 410
Query: 488 SKINGYKAYDPENRNGNGLRY--KKLHDPKGWITIDEISGSIITSKILDREVETPKNELY 545
S + A DP+ N +RY + D ID +G+I+T K LDRE +
Sbjct: 411 SLVGVVTARDPDAAN-RPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETA----GWH 465
Query: 546 NITVLAIDKDDRS--CTGTLAVNIEDVNDNPPEILQEY-VVIC---KPKMGYTDILAVDP 599
NITVLA++ D+ + +L + I DVNDNPPE+ Y +C KP I VD
Sbjct: 466 NITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDR 525
Query: 600 DEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQE-----YTIPITVKD 654
DEP G FYF L +P + +SL + D A + + ++ GF + +PI V D
Sbjct: 526 DEPQGGHRFYFRLVPEAPS-NPHFSLLDIQDNTAAV-HTQHVGFNRQEQDVFFLPILVVD 583
Query: 655 RAGQ--AATKLLRVNLCECTHP---TQCRATSRSTGVILGKWAILAILLGIALLFSVLLT 709
++T L + +C C C T+ L A++A+L+ + +L ++L
Sbjct: 584 SGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLL 643
Query: 710 LV 711
++
Sbjct: 644 IL 645
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 229 bits (585), Expect = 6e-60
Identities = 193/668 (28%), Positives = 322/668 (48%), Gaps = 55/668 (8%)
Query: 110 TVLLEHQ-------KKVSKTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESD 162
T+LL+ + KK++ +LRR KR W + E G ++ ++ +D
Sbjct: 21 TILLQEKPNSYLSSKKIAGLTKDDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTD 80
Query: 163 AAQ-NYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYA-STADG 220
+ + + Y ++G G +LF I+ +TG++ + +DREE ++ L A A G
Sbjct: 81 QDKGDGNLKYILTGDGAG----SLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTG 136
Query: 221 YSADLPLPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-R 279
+ I++ D NDN P FT+ +Y V E S GT+V V ATD D+ + ++ +
Sbjct: 137 RQVEPESEFIIKIHDINDNEPKFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAK 196
Query: 280 LKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTS 339
+ YSILQ P FSV P +G+I T + RE ++Y ++++ +DM GQ GL GT+
Sbjct: 197 VVYSILQGQP----YFSVDPESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTT 252
Query: 340 TCIITVTDSNDNAPTFRQNAYEAFVEENA-FNVEILRIPIEDKDLINTANWRVNFTILKG 398
T IT+TD N+N P F Q+ Y+ E+ + RI D D+ A + ++I +G
Sbjct: 253 TVNITLTDVNNNPPRFPQSTYQFNSPESVPLGTHLGRIKANDPDVGENAE--MEYSIAEG 310
Query: 399 NENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALV 458
+ F + TDK+T EG+++V + L++E L + +N P R + + A+V
Sbjct: 311 DGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVV 370
Query: 459 TVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYK--KLHDPKG 516
+ V D+DE P T + + + E++ GS I AYDP+ RN N ++Y + D
Sbjct: 371 KISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARN-NLIKYSVDRHTDMDR 429
Query: 517 WITIDEISGSIITSKILDREVETPKNELYNITVLA--IDKDDRSCTGTLAVNIEDVNDNP 574
I +GSI T K LDRE + +NITV A I+ +S + + I D+ND+
Sbjct: 430 IFGIHSENGSIFTLKALDRE----SSPWHNITVTATEINNPKQSSHIPVFIRILDINDHA 485
Query: 575 PEILQEY-VVIC---KPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVND 630
PE Y +C KP + +D D+P G F+F P ++ +++ D
Sbjct: 486 PEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFE-PVPEFTLNPNFTIVDNKD 544
Query: 631 TAARLSYQKNA----GFQEYTIPITV--KDRAGQAATKLLRVNLCECTHP---TQCRATS 681
A + +K+ Y +PI + D Q++T L + +C C + C A +
Sbjct: 545 NTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEA 604
Query: 682 RSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDL------AQQNLIIS 735
L A++AILL + +L +++ +F A K +R E L + N++
Sbjct: 605 LILSAGLSTGALVAILLCVLILLILVV-----LFAALKRQRKKEPLIISKDDVRDNIVTY 659
Query: 736 NTEAPGDD 743
N E G++
Sbjct: 660 NDEGGGEE 667
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 216 bits (550), Expect = 7e-56
Identities = 180/611 (29%), Positives = 294/611 (48%), Gaps = 47/611 (7%)
Query: 127 ETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQ-NYTVFYSISGRGVDKEPLNL 185
+ +L R+KR W + E GP P+ + ++ +D + + Y +SG G +
Sbjct: 53 QRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAG----TI 108
Query: 186 FYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLP----IRVEDENDNHP 241
F I TG++ + +DREE + L A A + PL P I+V+D NDN P
Sbjct: 109 FQINDVTGDIHAIKRLDREEKAEYTLTAQAVD---WETSKPLEPPSEFIIKVQDINDNAP 165
Query: 242 VFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGLFSVHPS 300
F Y+ V E S GT+V V ATD D+P ++ +L YSIL+ P FS+ P
Sbjct: 166 EFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQP----YFSIEPE 221
Query: 301 TGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAY 360
T +I T +DRE ++Y ++++ +DM G GL GT+T +T+TD NDN P F Q+ Y
Sbjct: 222 TAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLY 281
Query: 361 EAFVEEN-AFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSV 419
V E+ I R+ D+D+ N + ++ I+ G+ F+I++D + +G++ +
Sbjct: 282 HFSVPEDVVLGTAIGRVKANDQDI--GENAQSSYDIIDGDGTALFEITSDAQAQDGIIRL 339
Query: 420 VKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVR 479
KPL++E + L++ N R R + A V + V D DE P + +
Sbjct: 340 RKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLE 399
Query: 480 IKENLAVGSKINGYKAYDPENRNGNGLRYK--KLHDPKGWITIDEISGSIITSKILDREV 537
+ EN A+ S I A DP+ + +R+ + D + I+ G I + LDRE+
Sbjct: 400 VHENAALNSVIGQVTARDPD-ITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDREL 458
Query: 538 ETPKNELYNITVLAIDKDDRSCTG--TLAVNIEDVNDNPPEILQEY-VVIC---KPKMGY 591
+NIT++A + + S +A+ + DVNDN PE EY +C KP
Sbjct: 459 SV----WHNITIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVI 514
Query: 592 TDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLT-KVNDTAARLSYQKNAGF-----QE 645
+ A+D D+P +G F +SL PE+ + T K N+ + K+ GF +
Sbjct: 515 QTVSAMDKDDPKNGHYFLYSL---LPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEV 571
Query: 646 YTIPITVKDRAGQ--AATKLLRVNLCECTHP---TQCRATSRSTGVILGKWAILAILLGI 700
Y +PI + D ++T L + +C C++ C + + L A++AIL I
Sbjct: 572 YLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACI 631
Query: 701 ALLFSVLLTLV 711
LL +++ V
Sbjct: 632 ILLLVIVVLFV 642
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,668,980
Number of Sequences: 37866
Number of extensions: 1502762
Number of successful extensions: 6670
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 196
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3144
Number of HSP's gapped (non-prelim): 924
length of query: 839
length of database: 18,247,518
effective HSP length: 111
effective length of query: 728
effective length of database: 14,044,392
effective search space: 10224317376
effective search space used: 10224317376
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.