Search of human proteins with 148232726

Search of human proteins with 148232726

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148232726 calcium channel, voltage-dependent, beta 2 subunit
isoform 1 [Homo sapiens]
         (605 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148232726 calcium channel, voltage-dependent, beta 2 subunit ...  1213   0.0  
gi|148223541 calcium channel, voltage-dependent, beta 2 subunit ...  1179   0.0  
gi|147898681 calcium channel, voltage-dependent, beta 2 subunit ...  1179   0.0  
gi|45359834 calcium channel, voltage-dependent, beta 2 subunit i...  1179   0.0  
gi|148226485 calcium channel, voltage-dependent, beta 2 subunit ...  1179   0.0  
gi|147901383 calcium channel, voltage-dependent, beta 2 subunit ...  1074   0.0  
gi|147904948 calcium channel, voltage-dependent, beta 2 subunit ...  1073   0.0  
gi|45359842 calcium channel, voltage-dependent, beta 2 subunit i...  1073   0.0  
gi|40804468 calcium channel, voltage-dependent, beta 1 subunit i...   681   0.0  
gi|40804470 calcium channel, voltage-dependent, beta 1 subunit i...   666   0.0  
gi|40804472 calcium channel, voltage-dependent, beta 1 subunit i...   624   e-179
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i...   613   e-175
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i...   613   e-175
gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i...   613   e-175
gi|40316928 calcium channel, voltage-dependent, beta 3 subunit [...   533   e-151
gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ...   516   e-146
gi|50962882 G patch domain containing 8 [Homo sapiens]                 58   3e-08
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi...    54   5e-07
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]           52   2e-06
gi|4504487 histidine rich calcium binding protein precursor [Hom...    50   5e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   2e-05
gi|9945320 cyclin L1 [Homo sapiens]                                    48   3e-05
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    47   4e-05
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    46   1e-04
gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo sap...    45   1e-04
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     45   2e-04
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          44   4e-04
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    43   7e-04
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]        43   7e-04
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]        43   7e-04

>gi|148232726 calcium channel, voltage-dependent, beta 2 subunit
           isoform 1 [Homo sapiens]
          Length = 605

 Score = 1213 bits (3138), Expect = 0.0
 Identities = 605/605 (100%), Positives = 605/605 (100%)

Query: 1   MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV 60
           MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV
Sbjct: 1   MQCCGLVHRRRVRVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV 60

Query: 61  AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS 120
           AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS
Sbjct: 61  AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS 120

Query: 121 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE 180
           PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE
Sbjct: 121 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE 180

Query: 181 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE 240
           ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE
Sbjct: 181 ENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE 240

Query: 241 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ 300
           VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ
Sbjct: 241 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ 300

Query: 301 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ 360
           SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ
Sbjct: 301 SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ 360

Query: 361 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL 420
           AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL
Sbjct: 361 AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL 420

Query: 421 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS 480
           LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS
Sbjct: 421 LSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSS 480

Query: 481 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH 540
           APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH
Sbjct: 481 APHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETH 540

Query: 541 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 600
           GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD
Sbjct: 541 GSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 600

Query: 601 VYIRQ 605
           VYIRQ
Sbjct: 601 VYIRQ 605


>gi|148223541 calcium channel, voltage-dependent, beta 2 subunit
           isoform 6 [Homo sapiens]
          Length = 632

 Score = 1179 bits (3051), Expect = 0.0
 Identities = 590/592 (99%), Positives = 590/592 (99%)

Query: 14  VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73
           V  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA
Sbjct: 41  VRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 100

Query: 74  HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133
           HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ
Sbjct: 101 HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 160

Query: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 193
           RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP
Sbjct: 161 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 220

Query: 194 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 253
           SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL
Sbjct: 221 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 280

Query: 254 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 313
           KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL
Sbjct: 281 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 340

Query: 314 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 373
           QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK
Sbjct: 341 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 400

Query: 374 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 433
           LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS
Sbjct: 401 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 460

Query: 434 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 493
           PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG
Sbjct: 461 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 520

Query: 494 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553
           LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR
Sbjct: 521 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 580

Query: 554 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 605
           SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 581 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 632


>gi|147898681 calcium channel, voltage-dependent, beta 2 subunit
           isoform 2 [Homo sapiens]
          Length = 660

 Score = 1179 bits (3051), Expect = 0.0
 Identities = 590/592 (99%), Positives = 590/592 (99%)

Query: 14  VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73
           V  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA
Sbjct: 69  VRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 128

Query: 74  HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133
           HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ
Sbjct: 129 HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 188

Query: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 193
           RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP
Sbjct: 189 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 248

Query: 194 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 253
           SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL
Sbjct: 249 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 308

Query: 254 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 313
           KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL
Sbjct: 309 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 368

Query: 314 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 373
           QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK
Sbjct: 369 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 428

Query: 374 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 433
           LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS
Sbjct: 429 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 488

Query: 434 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 493
           PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG
Sbjct: 489 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 548

Query: 494 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553
           LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR
Sbjct: 549 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 608

Query: 554 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 605
           SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 609 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 660


>gi|45359834 calcium channel, voltage-dependent, beta 2 subunit
           isoform 7 [Homo sapiens]
          Length = 612

 Score = 1179 bits (3049), Expect = 0.0
 Identities = 589/589 (100%), Positives = 589/589 (100%)

Query: 17  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 76
           GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED
Sbjct: 24  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 83

Query: 77  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 136
           DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK
Sbjct: 84  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 143

Query: 137 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 196
           QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN
Sbjct: 144 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 203

Query: 197 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 256
           SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 204 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 263

Query: 257 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 316
           FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV
Sbjct: 264 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 323

Query: 317 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 376
           VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ
Sbjct: 324 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 383

Query: 377 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 436
           CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL
Sbjct: 384 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 443

Query: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496
           ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR
Sbjct: 444 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 503

Query: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 556
           QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD
Sbjct: 504 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 563

Query: 557 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 605
           VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 564 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 612


>gi|148226485 calcium channel, voltage-dependent, beta 2 subunit
           isoform 3 [Homo sapiens]
          Length = 606

 Score = 1179 bits (3049), Expect = 0.0
 Identities = 589/589 (100%), Positives = 589/589 (100%)

Query: 17  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 76
           GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED
Sbjct: 18  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 77

Query: 77  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 136
           DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK
Sbjct: 78  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 137

Query: 137 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 196
           QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN
Sbjct: 138 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 197

Query: 197 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 256
           SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 198 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 257

Query: 257 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 316
           FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV
Sbjct: 258 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 317

Query: 317 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 376
           VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ
Sbjct: 318 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 377

Query: 377 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 436
           CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL
Sbjct: 378 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 437

Query: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496
           ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR
Sbjct: 438 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 497

Query: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 556
           QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD
Sbjct: 498 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 557

Query: 557 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 605
           VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 558 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 606


>gi|147901383 calcium channel, voltage-dependent, beta 2 subunit
           isoform 5 [Homo sapiens]
          Length = 622

 Score = 1074 bits (2777), Expect = 0.0
 Identities = 549/592 (92%), Positives = 551/592 (93%), Gaps = 38/592 (6%)

Query: 14  VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73
           V  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA
Sbjct: 69  VRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 128

Query: 74  HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133
           HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ
Sbjct: 129 HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 188

Query: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 193
           RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA                        
Sbjct: 189 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA------------------------ 224

Query: 194 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 253
                     K+K+    K TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL
Sbjct: 225 ----------KQKQ----KSTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 270

Query: 254 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 313
           KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL
Sbjct: 271 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 330

Query: 314 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 373
           QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK
Sbjct: 331 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 390

Query: 374 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 433
           LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS
Sbjct: 391 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 450

Query: 434 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 493
           PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG
Sbjct: 451 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 510

Query: 494 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553
           LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR
Sbjct: 511 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 570

Query: 554 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 605
           SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 571 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 622


>gi|147904948 calcium channel, voltage-dependent, beta 2 subunit
           isoform 8 [Homo sapiens]
          Length = 608

 Score = 1073 bits (2774), Expect = 0.0
 Identities = 549/592 (92%), Positives = 552/592 (93%), Gaps = 24/592 (4%)

Query: 14  VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73
           V  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA
Sbjct: 41  VRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 100

Query: 74  HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133
           HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ
Sbjct: 101 HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 160

Query: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 193
           RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSS          A+E D          
Sbjct: 161 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK------SADEQD---------- 204

Query: 194 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 253
                     K   + +   TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL
Sbjct: 205 --------QWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 256

Query: 254 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 313
           KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL
Sbjct: 257 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 316

Query: 314 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 373
           QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK
Sbjct: 317 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 376

Query: 374 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 433
           LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS
Sbjct: 377 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 436

Query: 434 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 493
           PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG
Sbjct: 437 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 496

Query: 494 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553
           LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR
Sbjct: 497 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 556

Query: 554 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 605
           SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 557 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 608


>gi|45359842 calcium channel, voltage-dependent, beta 2 subunit
           isoform 4 [Homo sapiens]
          Length = 636

 Score = 1073 bits (2774), Expect = 0.0
 Identities = 549/592 (92%), Positives = 552/592 (93%), Gaps = 24/592 (4%)

Query: 14  VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73
           V  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA
Sbjct: 69  VRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 128

Query: 74  HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133
           HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ
Sbjct: 129 HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 188

Query: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 193
           RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSS          A+E D          
Sbjct: 189 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK------SADEQD---------- 232

Query: 194 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 253
                     K   + +   TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL
Sbjct: 233 --------QWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 284

Query: 254 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 313
           KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL
Sbjct: 285 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 344

Query: 314 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 373
           QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK
Sbjct: 345 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 404

Query: 374 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 433
           LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS
Sbjct: 405 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 464

Query: 434 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 493
           PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG
Sbjct: 465 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 524

Query: 494 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553
           LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR
Sbjct: 525 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 584

Query: 554 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 605
           SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 585 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 636


>gi|40804468 calcium channel, voltage-dependent, beta 1 subunit
           isoform 1 [Homo sapiens]
          Length = 598

 Score =  681 bits (1758), Expect = 0.0
 Identities = 370/595 (62%), Positives = 431/595 (72%), Gaps = 55/595 (9%)

Query: 14  VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73
           V  GSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAVRTNV Y+ +
Sbjct: 55  VRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPS 114

Query: 74  HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133
             D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL+++RL  EQ
Sbjct: 115 PGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQ 174

Query: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 193
           + +Q +  SSKSG NSSSSLGD+V  +R+ TPP+SA                        
Sbjct: 175 KLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASA------------------------ 210

Query: 194 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 253
                     K+K+    K TEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFL
Sbjct: 211 ----------KQKQ----KSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFL 256

Query: 254 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 313
           KHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERIFELARTL
Sbjct: 257 KHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTL 316

Query: 314 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 373
           QLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++K
Sbjct: 317 QLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEK 376

Query: 374 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 433
           LAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+AT++L  S
Sbjct: 377 LAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAAS 436

Query: 434 PTLASNSQG---SQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGT 490
           P   SN QG   + GDQ      P+  A+         P +  Q      + H   R+GT
Sbjct: 437 PAPVSNLQGPYLASGDQ------PLERATGEHASMHEYPGELGQPPGLYPSSHPPGRAGT 490

Query: 491 SRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRES 550
            R LSRQ+TFD++T  SR+SAY E         VD      +     +  G      R+ 
Sbjct: 491 LRALSRQDTFDADTPGSRNSAYTE----LGDSCVDMETDPSEGPGLGDPAGGGTPPARQG 546

Query: 551 RHRSRDVDREQDHNECNKQRSRHKSKDRYC-EKDGEVISKKRNEAGEWNRDVYIR 604
                + D E+   E    R+R ++K RYC E  G V+ + +NE   W R VYIR
Sbjct: 547 SWEDEEEDYEE---ELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR 598


>gi|40804470 calcium channel, voltage-dependent, beta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 523

 Score =  666 bits (1718), Expect = 0.0
 Identities = 334/435 (76%), Positives = 380/435 (87%), Gaps = 7/435 (1%)

Query: 14  VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73
           V  GSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAVRTNV Y+ +
Sbjct: 55  VRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPS 114

Query: 74  HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133
             D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL+++RL  EQ
Sbjct: 115 PGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQ 174

Query: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSS-------AIDIDATGLDAEENDIPA 186
           + +Q +  SSKSG NSSSSLGD+V  +R+ TPP+S       A ++D   L+ EE ++  
Sbjct: 175 KLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGE 234

Query: 187 NHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQ 246
              S K S +SVT+P    KR+PFFKKTEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQ
Sbjct: 235 QSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQ 294

Query: 247 KALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERI 306
           KALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERI
Sbjct: 295 KALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERI 354

Query: 307 FELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNV 366
           FELARTLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNV
Sbjct: 355 FELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNV 414

Query: 367 QMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLA 426
           Q+ A++KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+A
Sbjct: 415 QIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMA 474

Query: 427 TSSLPLSPTLASNSQ 441
           T++L  SP   SN Q
Sbjct: 475 TAALAASPAPVSNLQ 489


>gi|40804472 calcium channel, voltage-dependent, beta 1 subunit
           isoform 3 [Homo sapiens]
          Length = 478

 Score =  624 bits (1610), Expect = e-179
 Identities = 319/428 (74%), Positives = 359/428 (83%), Gaps = 38/428 (8%)

Query: 14  VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73
           V  GSA+SYTSRPSDSDVSLEEDREA+R+EAERQA AQLEKAKTKPVAFAVRTNV Y+ +
Sbjct: 55  VRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPS 114

Query: 74  HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133
             D+VPV G+AI+FE KDFLH+KEK+NNDWWIGRLVKEGCE+GFIPSPVKL+++RL  EQ
Sbjct: 115 PGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQ 174

Query: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 193
           + +Q +  SSKSG NSSSSLGD+V  +R+ TPP+SA                        
Sbjct: 175 KLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASA------------------------ 210

Query: 194 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 253
                     K+K+    K TEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFL
Sbjct: 211 ----------KQKQ----KSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFL 256

Query: 254 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 313
           KHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERIFELARTL
Sbjct: 257 KHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTL 316

Query: 314 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 373
           QLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++K
Sbjct: 317 QLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEK 376

Query: 374 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 433
           LAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+AT++L  S
Sbjct: 377 LAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAAS 436

Query: 434 PTLASNSQ 441
           P   SN Q
Sbjct: 437 PAPVSNLQ 444


>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
           isoform a [Homo sapiens]
          Length = 486

 Score =  613 bits (1582), Expect = e-175
 Identities = 339/537 (63%), Positives = 392/537 (72%), Gaps = 67/537 (12%)

Query: 17  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 76
           GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNVSY  A ++
Sbjct: 16  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75

Query: 77  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 136
           DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ  K
Sbjct: 76  DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 133

Query: 137 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 196
           +G+F+  KS GNSSSSLG++V  + ++TP S+A                           
Sbjct: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 166

Query: 197 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 256
                  K+K+    K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 167 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 215

Query: 257 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 316
           F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 216 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 275

Query: 317 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 376
           VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 276 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 335

Query: 377 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 436
           CPPE+FDVILDENQLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++L   PT 
Sbjct: 336 CPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTA 395

Query: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496
            S  Q          S  +R ++ + E   +E     +   +S   +HN R+  SR    
Sbjct: 396 ISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR---- 437

Query: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553
                S +Q SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 438 -NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 485


>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
           isoform c [Homo sapiens]
          Length = 502

 Score =  613 bits (1582), Expect = e-175
 Identities = 339/537 (63%), Positives = 392/537 (72%), Gaps = 67/537 (12%)

Query: 17  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 76
           GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNVSY  A ++
Sbjct: 32  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 91

Query: 77  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 136
           DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ  K
Sbjct: 92  DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 149

Query: 137 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 196
           +G+F+  KS GNSSSSLG++V  + ++TP S+A                           
Sbjct: 150 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 182

Query: 197 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 256
                  K+K+    K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 183 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 231

Query: 257 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 316
           F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 232 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 291

Query: 317 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 376
           VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 292 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 351

Query: 377 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 436
           CPPE+FDVILDENQLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++L   PT 
Sbjct: 352 CPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTA 411

Query: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496
            S  Q          S  +R ++ + E   +E     +   +S   +HN R+  SR    
Sbjct: 412 ISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR---- 453

Query: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553
                S +Q SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 454 -NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 501


>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
           isoform b [Homo sapiens]
          Length = 520

 Score =  613 bits (1582), Expect = e-175
 Identities = 339/537 (63%), Positives = 392/537 (72%), Gaps = 67/537 (12%)

Query: 17  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 76
           GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNVSY  A ++
Sbjct: 50  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 109

Query: 77  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 136
           DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ  K
Sbjct: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 167

Query: 137 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 196
           +G+F+  KS GNSSSSLG++V  + ++TP S+A                           
Sbjct: 168 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 200

Query: 197 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 256
                  K+K+    K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 201 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 249

Query: 257 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 316
           F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 250 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 309

Query: 317 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 376
           VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 310 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 369

Query: 377 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 436
           CPPE+FDVILDENQLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++L   PT 
Sbjct: 370 CPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTA 429

Query: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496
            S  Q          S  +R ++ + E   +E     +   +S   +HN R+  SR    
Sbjct: 430 ISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR---- 471

Query: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553
                S +Q SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 472 -NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 519


>gi|40316928 calcium channel, voltage-dependent, beta 3 subunit
           [Homo sapiens]
          Length = 484

 Score =  533 bits (1373), Expect = e-151
 Identities = 312/565 (55%), Positives = 367/565 (64%), Gaps = 98/565 (17%)

Query: 17  GSADSYTSRPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHE 75
           GSADSYTSRPS DSDVSLEEDRE+ RRE E QAQ QLE+AK KPVAFAVRTNVSY    +
Sbjct: 16  GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75

Query: 76  DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRA 135
           ++ PV G  ++FEAKDFLH+KEK++NDWWIGRLVKEG +I FIPSP +LE++RL+ EQ+A
Sbjct: 76  EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135

Query: 136 KQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSA 195
                                    R+S  PSS  DI              N RSP PS 
Sbjct: 136 -------------------------RRSGNPSSLSDI-------------GNRRSPPPSL 157

Query: 196 NSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 255
                  +K+K+    K+ EH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 158 -------AKQKQ----KQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 206

Query: 256 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 315
           RF+GRISITRVTAD+SLAKRSVLNNP K  IIERS+ RSS+AEVQSEIERIFELA++LQL
Sbjct: 207 RFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQL 266

Query: 316 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 375
           VVLDADTINHPAQL+KTSLAPIIV+VK+SSPKVLQRLI+SRGKSQ KHL VQM+A DKL 
Sbjct: 267 VVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLV 326

Query: 376 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP-LLSRTLATSSLPLSP 434
           QCPPE FDVILDENQLEDACEHLA+YLE YW+ATH P+   P P LL    A   L    
Sbjct: 327 QCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPA---PGPGLLGPPSAIPGLQNQQ 383

Query: 435 TLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGL 494
            L     G +G++ +                   P+++     S  A   + ++ T    
Sbjct: 384 LL-----GERGEEHS-------------------PLERDSLMPSDEASESSRQAWTG--- 416

Query: 495 SRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRS 554
                        R S ++E  EDY+  + D Y  HR H     T G       + + R 
Sbjct: 417 ----------SSQRSSRHLE--EDYADAYQDLYQPHRQH-----TSGLPSANGHDPQDRL 459

Query: 555 RDVDREQDHNECNKQRSRHKSKDRY 579
              D E +H++ N QR+R   KD Y
Sbjct: 460 LAQDSEHNHSDRNWQRNRPWPKDSY 484


>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
           isoform d [Homo sapiens]
          Length = 458

 Score =  516 bits (1330), Expect = e-146
 Identities = 304/537 (56%), Positives = 350/537 (65%), Gaps = 129/537 (24%)

Query: 17  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 76
           GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNVSY  A ++
Sbjct: 50  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 109

Query: 77  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 136
           DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ  K
Sbjct: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 167

Query: 137 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 196
           +G+F+  KS GNSSSSLG++V  + ++TP S+A                           
Sbjct: 168 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 200

Query: 197 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 256
                  K+K+    K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 201 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 249

Query: 257 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 316
           F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 250 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 309

Query: 317 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 376
           VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 310 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 369

Query: 377 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 436
           CPP                           +  H   S+  +P+  R+L TS        
Sbjct: 370 CPPS-------------------------QRMRHSNHSTENSPIERRSLMTS-------- 396

Query: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496
                                    +E    E  +KS++R SSS+ H             
Sbjct: 397 -------------------------DENYHNERARKSRNRLSSSSQH------------- 418

Query: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553
                     SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 419 ----------SRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 457


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 49/182 (26%), Positives = 74/182 (40%), Gaps = 30/182 (16%)

Query: 440 SQGSQGDQRTDRSAPIR----SASQAEEEPSVEP--VKKSQHRSSSSAPHHNHRSGTSRG 493
           SQ S GD+ +D ++  R    S SQ  EE   E    + S+ RS S   H +HRS     
Sbjct: 811 SQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSS---- 866

Query: 494 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYA------SHRDHNHRDETHGSSDHRH 547
              + ++ S +  S D +    +  YS D    Y+      S R H+  D  + SS HR 
Sbjct: 867 ---RRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRS 923

Query: 548 RESRHRSRDVD----------REQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEW 597
           +  ++ S D D          R + H    + RSR +S+   C +       +   A  W
Sbjct: 924 KRHKYSSSDDDYSLSCSQSRSRSRSHTR-ERSRSRGRSRSSSCSRSRSKRRSRSTTAHSW 982

Query: 598 NR 599
            R
Sbjct: 983 QR 984



 Score = 33.1 bits (74), Expect = 0.76
 Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 8/146 (5%)

Query: 438 SNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQ 497
           S S+   G + +   +  RS S + +  S +    S+ RS S   + ++   + R   R 
Sbjct: 850 SRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCY-SRQRSYSDDSYSDYSDRSRRHSKRS 908

Query: 498 ETFD-----SETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRH 552
              D     S    S+   Y    +DYS       +  R  +H  E   S       S  
Sbjct: 909 HDSDDSDYASSKHRSKRHKYSSSDDDYSLS--CSQSRSRSRSHTRERSRSRGRSRSSSCS 966

Query: 553 RSRDVDREQDHNECNKQRSRHKSKDR 578
           RSR   R +     + QRSR  S+DR
Sbjct: 967 RSRSKRRSRSTTAHSWQRSRSYSRDR 992


>gi|119943108 synapse-associated protein 102 isoform b [Homo
           sapiens]
          Length = 512

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 75/345 (21%), Positives = 136/345 (39%), Gaps = 45/345 (13%)

Query: 77  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPSPVKLENMRLQHEQ 133
           D  +P   +SF   D LHV    +++WW  RLV    E  +IG IPS  ++E    +   
Sbjct: 180 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEK---KERA 236

Query: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLD-AEENDIPANHRSPK 192
           R K  KF++      S+ S   I    +KS   S       +  + A+E+ I     +  
Sbjct: 237 RLKTVKFHARTGMIESNRS---IKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSN 293

Query: 193 PSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDF 252
            S +  +S   ++  + +   T     Y      RPV+++GP      + D +   L   
Sbjct: 294 TSDSESSSKGQEDAILSYEPVTRQEIHY-----ARPVIILGP------MKDRVNDDLISE 342

Query: 253 LKHRFEGRI-SITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ----------- 300
             H+F   +   TR   D      + ++    H ++ R      + + +           
Sbjct: 343 FPHKFGSCVPHTTRPRRD------NEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNL 396

Query: 301 --SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGK 358
             + I+ +  +A   +  +LD    N   +L +  L PI +++K   PK ++ L++   +
Sbjct: 397 YGTSIQSVRAVAERGKHCILDVSG-NAIKRLQQAQLYPIAIFIK---PKSIEALMEMNRR 452

Query: 359 SQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE 403
              +  N     A KL Q   E F  I+  + LE+    +   +E
Sbjct: 453 QTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIE 497


>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
          Length = 926

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 71/340 (20%), Positives = 131/340 (38%), Gaps = 38/340 (11%)

Query: 77  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPSPVKLENMRLQHEQ 133
           D  +P   ++F+  D LHV    +++WW  R V    E  E+G IPS  ++E    +   
Sbjct: 597 DSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEK---KERA 653

Query: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 193
           R K  KF S       +   G      RK    S           +E+    A+      
Sbjct: 654 RLKTVKFNS------KTRDKGQSFNDKRKKNLFSRKFPFYKNKDQSEQETSDADQHVTSN 707

Query: 194 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 253
           +++S +S   +E+ +  ++          V   RPV+++GP      + D +   L    
Sbjct: 708 ASDSESSYRGQEEYVLSYEPVNQ----QEVNYTRPVIILGP------MKDRINDDLISEF 757

Query: 254 KHRFEGRI-SITRVTADISL---------AKRSVLNNPSKHAIIERSNTRSSLAEVQSEI 303
             +F   +   TR   D  +         ++  +  +  +H  IE     + L    + +
Sbjct: 758 PDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHL--YGTSV 815

Query: 304 ERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKH 363
           + + E+A   +  +LD    N   +L    L PI +++K   PK ++ +++   +   + 
Sbjct: 816 QSVREVAEKGKHCILDVSG-NAIKRLQIAQLYPISIFIK---PKSMENIMEMNKRLTEEQ 871

Query: 364 LNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE 403
                  A KL Q   E F  I+  + LED    +   +E
Sbjct: 872 ARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIE 911


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 9/148 (6%)

Query: 459 SQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAY--VEPK 516
           S  + E   E V K            +H+ G   G+S +E F     ++R       E  
Sbjct: 84  SHPDREKEDEDVSKEYGHLLPGHRSQDHKVG-DEGVSGEEVFAEHGGQARGHRGHGSEDT 142

Query: 517 EDYSHDHVDHYASHRDHNHRDETHG---SSDHRHRESRHRSRDVDREQDHNECNKQRSRH 573
           ED S +H  H  SHR H+H+DE      SS+H H   RH  R  D E D  E  ++    
Sbjct: 143 ED-SAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGE--EEEEEE 199

Query: 574 KSKDRYCEKDGEVISKKRNEAGEWNRDV 601
           + ++    + G    + R    E + DV
Sbjct: 200 EEEEEASTEYGHQAHRHRGHGSEEDEDV 227



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 33/141 (23%), Positives = 53/141 (37%), Gaps = 16/141 (11%)

Query: 446 DQRTDRSAPIRSASQAEEEPSVEPVKKS-QHRSSSS------APHHNHRSGTSRGLSRQE 498
           D   D         + EEE S E   ++ +HR   S      +  H+H   + R    +E
Sbjct: 186 DGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEE 245

Query: 499 TFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSR--- 555
             D +  +  D    +  +D S ++      H+ H   ++   S  H HR+  HR R   
Sbjct: 246 DDDDDDDDDDD----DDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHE 301

Query: 556 --DVDREQDHNECNKQRSRHK 574
             D D +    E   Q  RH+
Sbjct: 302 EDDNDDDDVSTEYGHQAHRHQ 322



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 23/100 (23%), Positives = 37/100 (37%), Gaps = 6/100 (6%)

Query: 484 HNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSS 543
           H+HR  + R  S +E  + +   S +  +       +H H DH     +    +  H   
Sbjct: 288 HHHRDPSHRHRSHEEDDNDDDDVSTEYGH------QAHRHQDHRKEEVEAVSGEHHHHVP 341

Query: 544 DHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD 583
           DHRH+  R    D D   +      Q   H   D   E++
Sbjct: 342 DHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEE 381



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 25/126 (19%), Positives = 48/126 (38%), Gaps = 8/126 (6%)

Query: 453 APIRSASQAEEEPSVEPVKKSQHRSSSSAPHH--NHRSGTSRGLSRQETFDSETQESRDS 510
           AP    S  +EE         Q  S     HH   H     R   R++  + E ++  D 
Sbjct: 438 APSHRQSHQDEETG-----HGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDP 492

Query: 511 AYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQR 570
              E ++D S +  +    H   +  DE      H    ++    + D+E++  E +++R
Sbjct: 493 GSHE-EDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEER 551

Query: 571 SRHKSK 576
              +++
Sbjct: 552 REERAE 557


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 17/177 (9%)

Query: 412 PSSSLPNPLLSRTLATSSLPLSPTLASN---SQGSQGDQRTDRSAPI------RSASQAE 462
           P    P PLL+     S  PL+ T  S    +  S+     DRS P       +S+S   
Sbjct: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420

Query: 463 EEPSVEPVKKSQHRSSS-SAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSH 521
             PS +P K S+H SSS  +P      G+ R +S   T       S++ ++   K D SH
Sbjct: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT-------SKNRSHGRAKRDKSH 473

Query: 522 DHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDR 578
            H       R  +      G S  R    R  SR    +   +   ++  R +S  R
Sbjct: 474 SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQR 530



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 30/136 (22%), Positives = 56/136 (41%), Gaps = 11/136 (8%)

Query: 412 PSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVK 471
           P+   P P      ++SS   +P      +     +R++ S+P R   ++         K
Sbjct: 163 PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSS--------K 214

Query: 472 KSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHR 531
           K +HRS S +    HRS T +  S++++ D + + SR S    PK   +H      ++  
Sbjct: 215 KKKHRSESESKKRKHRSPTPK--SKRKSKDKKRKRSR-STTPAPKSRRAHRSTSADSASS 271

Query: 532 DHNHRDETHGSSDHRH 547
               R  +  ++   H
Sbjct: 272 SDTSRSRSRSAAAKTH 287



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 42/187 (22%), Positives = 69/187 (36%), Gaps = 21/187 (11%)

Query: 412  PSSSLPNPLLSRTLA-TSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPV 470
            P +  P  L  R+ + +SS    P+   +S      +   +S   R  S++  EP  +  
Sbjct: 1624 PKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSR 1683

Query: 471  KKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSET--------QESRDSAYVEPKEDYSHD 522
               + RSS S+P    ++  SR  SR  +   ET        + S   +  EP E     
Sbjct: 1684 TPPRRRSSRSSPELTRKARLSR-RSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS 1742

Query: 523  HVDHYA--------SHRDHNHRDETHGSSDHRHRESRHRSRDV---DREQDHNECNKQRS 571
                 A        S R  +   +  G    R R  R ++R     DR       +++R 
Sbjct: 1743 RRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQ 1802

Query: 572  RHKSKDR 578
            R +S+ R
Sbjct: 1803 RSRSRSR 1809



 Score = 33.1 bits (74), Expect = 0.76
 Identities = 28/119 (23%), Positives = 41/119 (34%)

Query: 110  KEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSA 169
            KE    G  P P   +  R      +      SS S  +SSSS      SS  S+  SS+
Sbjct: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646

Query: 170  IDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRP 228
                      +    PA+ + P P      SP      +   +   ++P     PS +P
Sbjct: 2647 SSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQP 2705



 Score = 32.7 bits (73), Expect = 0.99
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 18/93 (19%)

Query: 413 SSSLPNPLLSRTLATSSLPLSPTLASNS---------------QGSQGDQRTDRSAPIRS 457
           S SL +P   R+ A S L L  +L+ +S                GS   +   R+ P RS
Sbjct: 759 SRSLSSP---RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS 815

Query: 458 ASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGT 490
            S +   P  +    S+   SSS+PH   +SGT
Sbjct: 816 RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGT 848



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 38/154 (24%), Positives = 59/154 (38%), Gaps = 14/154 (9%)

Query: 433  SPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGT-- 490
            SP    +S+ S   +R     P  S  ++    S  P K+S+ R +S A H   RS T  
Sbjct: 1824 SPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSR-ASPATHRRSRSRTPL 1882

Query: 491  -SRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNH-----RDETHGSSD 544
             SR  SR  T     + SR    V  +   S       +  R  +      R  +   + 
Sbjct: 1883 ISRRRSRSRTSPVSRRRSRSRTSVTRRR--SRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940

Query: 545  HRHRESRHRSRDVDREQDHNE---CNKQRSRHKS 575
               R SR R+  V R +  +      ++RSR ++
Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRT 1974



 Score = 30.0 bits (66), Expect = 6.4
 Identities = 28/120 (23%), Positives = 47/120 (39%), Gaps = 16/120 (13%)

Query: 408  ATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIR---------SA 458
            A  P      +   S + ++SS   S + +S+S GS        S P++         S 
Sbjct: 2523 ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP 2582

Query: 459  SQAEEE-------PSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSA 511
            + A +E       P   P K+ +  SSSS+   +  S +S   S   +  S +  S  S+
Sbjct: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642


>gi|9945320 cyclin L1 [Homo sapiens]
          Length = 526

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 16/142 (11%)

Query: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496
           AS S  +   + + RS   RSAS++          +S+ RS +   H+N+R       SR
Sbjct: 371 ASKSPYNGVRKDSKRSRNSRSASRSRSRT------RSRSRSHTPRRHYNNRR------SR 418

Query: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 556
             T+ S ++    S    P+  ++H      A H     RD+   S+ H H+  + RSR 
Sbjct: 419 SGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHT----RDDLKSSNRHGHKRKKSRSRS 474

Query: 557 VDREQDHNECNKQRSRHKSKDR 578
             + +DH++  K+    +   R
Sbjct: 475 QSKSRDHSDAAKKHRHERGHHR 496


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 38/151 (25%), Positives = 64/151 (42%), Gaps = 12/151 (7%)

Query: 461 AEEEPSVEPVKKSQHRSSSSAPHHN-HRSGTSRGLSRQETFDSETQESRDSAYVEPKEDY 519
           A E+ S +  KK +    S +P  + H    SR  SR+    S+ +  +  +    KE  
Sbjct: 12  APEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71

Query: 520 SHDHVDHYA-SHRDHNHRDETHGSSDHRHR-------ESRH--RSRDVDREQDHNECNKQ 569
            H+  D  +  H+   H D+ H S   R R       E RH  + R   R + H+    +
Sbjct: 72  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131

Query: 570 RSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 600
             RH+S+ R   K     S++R ++   +R+
Sbjct: 132 ERRHRSRSRE-RKKSRSRSRERKKSRSRSRE 161



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 39/177 (22%), Positives = 72/177 (40%), Gaps = 28/177 (15%)

Query: 450 DRSAPIRSASQAEEEPSVEPVKKSQH-------------RSSSSAPHHNHRSGTSRGLSR 496
           ++++P R   + + E SV P     H             +S +    H  RS +  G  R
Sbjct: 14  EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEG-RR 72

Query: 497 QETFDSETQESRDSAY--VEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRH-----RE 549
            E+ D  +++ +   +   E   D   + ++   +  D + R E   S    H     RE
Sbjct: 73  HESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE 132

Query: 550 SRHRSRDVDREQDHNEC-------NKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNR 599
            RHRSR  +R++  +         ++ R R KS+ R  E+   + S+ R+ +   +R
Sbjct: 133 RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 189



 Score = 36.2 bits (82), Expect = 0.089
 Identities = 42/170 (24%), Positives = 64/170 (37%), Gaps = 18/170 (10%)

Query: 438 SNSQGSQGDQRTDRSA-PIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496
           S S+  +  +++D      RS S+++E    E   KS  +  S   H++    + +G  R
Sbjct: 43  SRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEE-HNDKEHSSDKG--R 99

Query: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE------- 549
           +    SE  E R     E K      H    +  R H  R      S  R RE       
Sbjct: 100 ERLNSSENGEDRHKRK-ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSR 158

Query: 550 ------SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE 593
                 SR RSR+  R       ++ R RH+++ R   +      KKR E
Sbjct: 159 SRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIE 208


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/167 (25%), Positives = 61/167 (36%), Gaps = 20/167 (11%)

Query: 442 GSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFD 501
           G +G +  DR    R +       S+ P  +   R S S  HH    G+S    R+   +
Sbjct: 244 GKEGAEEIDRHVERRRSRSPRR--SLSP--RRSPRRSRSRSHHREGHGSS-SFDRELERE 298

Query: 502 SETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQ 561
            E Q     A    KE      +D     R    R+     S  R R+   R RD +RE+
Sbjct: 299 KERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREK 358

Query: 562 DH---------------NECNKQRSRHKSKDRYCEKDGEVISKKRNE 593
           ++               NE  K+R R + + +     GEV  KK  E
Sbjct: 359 ENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKE 405



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 49/184 (26%), Positives = 69/184 (37%), Gaps = 38/184 (20%)

Query: 447 QRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGT---------------- 490
           QR +R A  R   + E   S    +  + R S S   H  RS +                
Sbjct: 302 QRLEREAKER---EKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREK 358

Query: 491 --SRGLSRQETFD----SETQESRDSAYVEPKEDYSHDHVD---HYASHRDHNHRDETHG 541
              RG  R   +D    +E ++ R+ +    KE  S   V+   H     D  HRD+   
Sbjct: 359 ENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRD 418

Query: 542 S------SDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAG 595
           S      S  R RE +HRSR   R    N   + RSR K K    + + +  S KR+ +G
Sbjct: 419 SKKEKKHSRSRSRERKHRSRSRSR----NAGKRSRSRSKEKSSKHKNESKEKSNKRSRSG 474

Query: 596 EWNR 599
              R
Sbjct: 475 SQGR 478



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 36/174 (20%), Positives = 65/174 (37%), Gaps = 18/174 (10%)

Query: 439 NSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQE 498
           N +  + ++  +RS   RS  + EE+   E     +HR          +   SR   R+ 
Sbjct: 376 NEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKH 435

Query: 499 TFDSETQESRDSAYVEPKEDYS-HDHVDHYASHR-----DHNHRDETHGSSDHRHRES-- 550
              S ++ +   +    KE  S H +     S++          D    S    H  S  
Sbjct: 436 RSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKE 495

Query: 551 ----RHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 600
               R RS++   ++DH++   Q  +H   DR   +  + I ++  E    N+D
Sbjct: 496 KSRKRSRSKERSHKRDHSDSKDQSDKH---DR---RRSQSIEQESQEKQHKNKD 543



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 34/157 (21%), Positives = 61/157 (38%), Gaps = 8/157 (5%)

Query: 438 SNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQ 497
           S S+  +GD+R DR       ++       +  K+  +           RS   R  SR 
Sbjct: 340 SRSRDRKGDRR-DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQR--SRG 396

Query: 498 ETFDSETQESRDSA-YVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 556
           E  + + +E +D   + + K D   +     +  R+  HR      S  R+   R RSR 
Sbjct: 397 EVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSR----SRSRNAGKRSRSRS 452

Query: 557 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE 593
            ++   H   +K++S  +S+     +   V   K+ E
Sbjct: 453 KEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 38/171 (22%), Positives = 62/171 (36%), Gaps = 11/171 (6%)

Query: 423 RTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAP 482
           R+L+    P      S+ +   G    DR        Q  E  + E  ++ + R S S  
Sbjct: 265 RSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKE--REKERRRSRSID 322

Query: 483 HHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGS 542
                 G  R  SR          SRD        D   +  +     RD ++ D+  G+
Sbjct: 323 R-----GLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDY-DKERGN 376

Query: 543 SDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE 593
              + RE   RSR+  +EQ      +++   + KD    +D +  SKK  +
Sbjct: 377 EREKERE---RSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK 424


>gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo
           sapiens]
          Length = 558

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 16/134 (11%)

Query: 472 KSQHRSSS-------SAPHHNHRSGTSRGLSRQETFDSETQESRDSA-------YVEPKE 517
           +SQ+ S S       S  HH   S TSRG  ++E    + ++SRD         Y + ++
Sbjct: 284 RSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKRED-QHQQKQSRDQENHYTDRDYRKERD 342

Query: 518 DYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKD 577
            + H    H  SH   + +++   + D R R  R   R+ DRE+ +++  ++R R ++  
Sbjct: 343 SHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREK-YSQREQERDRQQNDQ 401

Query: 578 RYCEKDGEVISKKR 591
               + GE   K +
Sbjct: 402 NRPSEKGEKEEKSK 415



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 10/116 (8%)

Query: 475 HRSSSSAPHHNHRSGTSRGLS-RQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDH 533
           HRS +    H+      RG S R  T  S T    +    + ++  S D  +HY   RD+
Sbjct: 283 HRSQN----HSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQSRDQENHYTD-RDY 337

Query: 534 NHRDETHGSSDHRHRES---RHRSRDVDREQDHNE-CNKQRSRHKSKDRYCEKDGE 585
               ++H   +  HR+S   RH   D  R +D  E  ++   R K +++Y +++ E
Sbjct: 338 RKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQE 393



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 71/348 (20%), Positives = 131/348 (37%), Gaps = 37/348 (10%)

Query: 272 LAKRSVLNNPS----KHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPA 327
           L K SV  N S    + ++ E     ++  +   + +   + A      V + D+I    
Sbjct: 23  LQKPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEM 82

Query: 328 QLSKTSLAPIIVYVKISSPKVLQRLIKS---RGKSQAKHLNVQMVAADKLAQCP------ 378
           Q  K    P ++  K   PK +  L+K+   R K Q K +  ++    ++ +        
Sbjct: 83  QKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEA 142

Query: 379 --PELFDVILDENQLEDACEHLADYLEAYWKATHPPS-SSLPNPLLSRTLATSSLPLSPT 435
                +   L E   E+  E  A  LEA    T     S     LL++ +    +P    
Sbjct: 143 FVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSF 202

Query: 436 LASNSQGSQGDQRTDRSAPIRSASQAEEEPSV---------EPVKKSQHRSSSSAPHHNH 486
             + S G + ++    S  + S ++  +E  +          P   S   + SSA     
Sbjct: 203 REARS-GIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIE 261

Query: 487 RSGTS-RGLSRQETFDSETQESRDSAYVE-PKEDYSHD---HVDHYASHRDHNHRDETHG 541
            +  + R     ET +++ +  R   +   P E+  H    H     + R H  R++ H 
Sbjct: 262 ETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQ 321

Query: 542 SSDHRHRESRHRSRDVDREQD---HNECNKQRS---RHKSKDRYCEKD 583
               R +E+ +  RD  +E+D   H E + + S   RH+ +D+   +D
Sbjct: 322 QKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARD 369



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 33/147 (22%), Positives = 53/147 (36%), Gaps = 10/147 (6%)

Query: 446 DQRTDRSAPIRSASQAEEEPSVEPVKKSQH-RSSSSAPHHNHRSGTSRGLSRQETFDSET 504
           D    R A  R +     E   +P  + Q  RS         R   S+    ++   ++ 
Sbjct: 342 DSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQ 401

Query: 505 QESRDSAYVEPKEDYSHDHV-------DHYASHRDHNHRDETHGSSDHRH--RESRHRSR 555
               +    E K     +H+       ++   +RD   R+    SS+     +ES   SR
Sbjct: 402 NRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGVQSSERNQDRKESSPNSR 461

Query: 556 DVDREQDHNECNKQRSRHKSKDRYCEK 582
             D+  D    NK R+  K K+R  EK
Sbjct: 462 AKDKFLDQERSNKMRNMAKDKERNQEK 488


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 62/257 (24%), Positives = 103/257 (40%), Gaps = 30/257 (11%)

Query: 333 SLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLE 392
           ++AP  V V+   P++ Q  ++++   Q     +   A +KLAQ   E  +  L   +  
Sbjct: 626 AVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKR 685

Query: 393 DACEHLADYLEAYWKA----------THPPSSSLPNPLLSRTLATSSLPLSPTLASNSQG 442
            A   L        +A          +   SS+ P PLL     T   PL PTL    + 
Sbjct: 686 KAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLL-----TGGRPL-PTL----EV 735

Query: 443 SQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDS 502
              D+ + +S   +   + EE+   +   K + R+ S +P + H S  SR  S      S
Sbjct: 736 KPPDRPSSKS---KDPPREEEKEKKKKKHKKRSRTRSRSPKY-HSSSKSRSRSH-----S 786

Query: 503 ETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQD 562
           + + S  SAY   +   S        +H     R+E    + +R   S   SR   R + 
Sbjct: 787 KAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRS 846

Query: 563 -HNECNKQRSRHKSKDR 578
            H +  K+RSR ++K +
Sbjct: 847 PHEKKKKRRSRSRTKSK 863


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 17/183 (9%)

Query: 433 SPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNH---RSG 489
           SPT  S+   S     T       S S++         K++  R  S +   NH   RS 
Sbjct: 258 SPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSR 317

Query: 490 TSRGL----SRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNH-----RDETH 540
           T +G+     R     S ++    +    P+   SH+   + +  R H+H     ++  H
Sbjct: 318 TRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDH 377

Query: 541 -GSSDHRHRESRHRSRDVDREQDHNEC---NKQRSRHKSKDRYCEKDGEVISKKRNEAGE 596
            GSS  R    R +S   ++++DH+     NK R R +S+  Y  +D    S+  N+A +
Sbjct: 378 RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARD-RSRSRSPNKARD 436

Query: 597 WNR 599
            +R
Sbjct: 437 CSR 439



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 35/162 (21%), Positives = 68/162 (41%), Gaps = 16/162 (9%)

Query: 433 SPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPH--HNHRSGT 490
           SP  A +   S+   +    +  RS ++A +        K++ RS S +P+   +H    
Sbjct: 406 SPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSR 465

Query: 491 SRGLSRQETFDSETQESRDSAYV-EPKEDYSHDHV----------DHYASHRDHNHRDET 539
           S   +R  +      + RD + +  P ++  H                +S ++ +HR   
Sbjct: 466 SPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSR 525

Query: 540 HGSSDHRHRESRHRSRDVDREQDHN---ECNKQRSRHKSKDR 578
             S + + R+SR  +++ DR Q  +   E   ++SR  SK+R
Sbjct: 526 SPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKER 567



 Score = 36.2 bits (82), Expect = 0.089
 Identities = 37/157 (23%), Positives = 65/157 (41%), Gaps = 12/157 (7%)

Query: 433 SPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAP-----HHNHR 487
           SP  A +   S+   +    +  RS ++A +        K +  S   +P     H   R
Sbjct: 442 SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR 501

Query: 488 SGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHR- 546
           S +     RQ    S+ ++ R S    P ++            RD   R ++   S+ R 
Sbjct: 502 SPSKERQCRQSRSSSKERDHRRSR--SPSKERQRRQSRSPNKERD---RSQSRSPSEERE 556

Query: 547 HRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD 583
           HR+SR  S++ DR +  +  +K+R R +S+    E+D
Sbjct: 557 HRQSRSPSKERDRRRWRSP-SKERERRQSRSSSEERD 592



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 45/180 (25%), Positives = 61/180 (33%), Gaps = 15/180 (8%)

Query: 406 WKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEP 465
           +KA     S  PN     + + S         S S   + D     S       +    P
Sbjct: 444 YKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSP 503

Query: 466 SVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVD 525
           S E   +    SS    H   RS +     RQ    S  +E   S    P E+      +
Sbjct: 504 SKERQCRQSRSSSKERDHRRSRSPSKERQRRQSR--SPNKERDRSQSRSPSEER-----E 556

Query: 526 HYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNEC---NKQ----RSRHKSKDR 578
           H  S      RD     S  + RE R +SR    E+DH+     NKQ    R R  SK++
Sbjct: 557 HRQSRSPSKERDRRRWRSPSKERE-RRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEK 615



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 42/174 (24%), Positives = 66/174 (37%), Gaps = 32/174 (18%)

Query: 406 WKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQG-SQGDQRTDRSAPIRSASQAEEE 464
           WK  H  + S      +R    S +       S+S+G SQ   RT R     + S+    
Sbjct: 307 WKRNHSRARSR-----TRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSR---N 358

Query: 465 PSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHV 524
           PS E   +S   S SS+   +HR  +S             +ES  S    P +   H   
Sbjct: 359 PSKE---RSHSHSRSSSKERDHRGSSS-----------PRKESGRSQSGSPNKQRDHSRS 404

Query: 525 DHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDR 578
                 RD +     + + D     S +++RD         C++ RS +K++DR
Sbjct: 405 RSPNKARDRSRSRSPYKARDRSRSRSPNKARD---------CSRSRSPYKARDR 449


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 32/164 (19%), Positives = 60/164 (36%), Gaps = 8/164 (4%)

Query: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496
           A   +  Q D+   R        + E E + +  ++ + +        +  S   R   R
Sbjct: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER 214

Query: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 556
           +   ++ET+  R +       D   D        R+     E     +    + R R RD
Sbjct: 215 ERETETETERKRQT-------DRERDRQRKTEREREKQAERERASERETERDKERERERD 267

Query: 557 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 600
            DR++D  +  ++R   + + R  E+D E   +KR    E  R+
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDRET-ERKRERQRERERE 310



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 33/150 (22%), Positives = 57/150 (38%), Gaps = 12/150 (8%)

Query: 446 DQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQ 505
           +++TDR    R+    E E      K+ + R        N +    R   R+     ET+
Sbjct: 280 ERQTDRKRQRRTERDRETER-----KRERQRERERERERNRKRERERERERERERQRETE 334

Query: 506 ESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNE 565
             R     E + +            R+     E    ++      R R R   RE++  E
Sbjct: 335 RDR-----EKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERE 389

Query: 566 CNKQRSRHKSKDRYCEK--DGEVISKKRNE 593
            ++ R R K ++R  EK  DG+  ++K+ E
Sbjct: 390 RDRDRDRQKERERQTEKDRDGQRETEKQRE 419



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 1/68 (1%)

Query: 529 SHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHN-ECNKQRSRHKSKDRYCEKDGEVI 587
           + R+ + + E     D   +  RHR R  DRE++   + +++R R + K+R  +K+ E  
Sbjct: 71  TERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERE 130

Query: 588 SKKRNEAG 595
           +++  E G
Sbjct: 131 TEREGERG 138



 Score = 37.4 bits (85), Expect = 0.040
 Identities = 30/118 (25%), Positives = 47/118 (39%), Gaps = 13/118 (11%)

Query: 469 PVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYA 528
           P  +   R       H    G  R  +RQ+    E +  R+    E + D   +      
Sbjct: 31  PGSQESPRRRGLGQAHKDADGDDRERNRQK----ERERRREKRQTERETDRKRERRREKD 86

Query: 529 SHRDHN-HRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGE 585
            HR  + HR+        R R++  R RD  RE       K+R+R K ++R  E++GE
Sbjct: 87  RHRKRDRHRERQRDREKERERQT-DRERDRQRE-------KERNRQKERERETEREGE 136



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 26/144 (18%), Positives = 59/144 (40%), Gaps = 11/144 (7%)

Query: 441 QGSQG-DQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQET 499
           +G +G D++TD          AE+E   +  ++ Q ++       N +    R  +RQE 
Sbjct: 134 EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE-----RNRQKEREREKNRQER 188

Query: 500 FDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDR 559
            + E Q  +++   +   +   +      +  +   + +T    D + +  R R +  +R
Sbjct: 189 RERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAER 248

Query: 560 E-----QDHNECNKQRSRHKSKDR 578
           E     +   +  ++R R + +DR
Sbjct: 249 ERASERETERDKERERERDRDRDR 272



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 34/157 (21%), Positives = 58/157 (36%), Gaps = 14/157 (8%)

Query: 444 QGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSE 503
           Q ++ TDR    R              K+ +HR             T R   RQ   +  
Sbjct: 70  QTERETDRKRERRREKDRHR-------KRDRHRERQRDREKERERQTDRERDRQREKERN 122

Query: 504 TQESRDSAYVEPKE---DYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDRE 560
            Q+ R+       E   D   D        RD     E     + + +  R+R ++ +RE
Sbjct: 123 RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE 182

Query: 561 ---QDHNECNKQRSR-HKSKDRYCEKDGEVISKKRNE 593
              Q+  E  +QR + +K++DR+ E+  E   ++  E
Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETE 219



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 36/169 (21%), Positives = 63/169 (37%), Gaps = 17/169 (10%)

Query: 441 QGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQ-----HRSSSSAPHHNHRSGTSRGLS 495
           Q  + ++  DR +      + E E   E  +K Q      R   +      ++   R   
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253

Query: 496 RQETFDSETQESRDSAYVEPKEDYSHDH-VDHYASHRDHNHRDETHGSSDHRHRE---SR 551
           R+   D E +  RD      +     +   D     R    R+        R RE    R
Sbjct: 254 RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER 313

Query: 552 HRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 600
           +R R+ +RE++     ++R R +  +R  EK+ E   +KR    E +R+
Sbjct: 314 NRKRERERERE-----RERERQRETERDREKERE---RKRKRQTEMDRE 354



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 39/202 (19%), Positives = 69/202 (34%), Gaps = 12/202 (5%)

Query: 399 ADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSA 458
           AD L   W        ++P     R   +   P    L    + + GD R       R  
Sbjct: 10  ADQLGTLWVEV-----TIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERER 64

Query: 459 SQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKED 518
            + + +   E  +K + R      H        R   R++  + +T   RD      KE 
Sbjct: 65  RREKRQTERETDRKRERRREKDR-HRKRDRHRERQRDREKERERQTDRERDRQ--REKER 121

Query: 519 YSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDRE-QDHNECNKQRSRHKSKD 577
                 +          RD     +D +    R R  + +RE Q   E  +Q  R++ K+
Sbjct: 122 NRQKERERETEREGERGRDR---QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178

Query: 578 RYCEKDGEVISKKRNEAGEWNR 599
           R  EK+ +   ++  +  + N+
Sbjct: 179 REREKNRQERRERERQREKENK 200


>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
          Length = 1337

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 10/78 (12%)

Query: 515 PKEDYSHDHVDHYASHRDHNHRDETHGSSD-HRHRESRHRSRDVDREQDHN------ECN 567
           P E  S + + HY    DH HRD +HG  + HR  + R R R  DR +  +      +  
Sbjct: 216 PSERRSPERLKHYD---DHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRG 272

Query: 568 KQRSRHKSKDRYCEKDGE 585
           +  SRH+S +R  E++ E
Sbjct: 273 RTPSRHRSYERSRERERE 290


>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
          Length = 1374

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 10/78 (12%)

Query: 515 PKEDYSHDHVDHYASHRDHNHRDETHGSSD-HRHRESRHRSRDVDREQDHN------ECN 567
           P E  S + + HY    DH HRD +HG  + HR  + R R R  DR +  +      +  
Sbjct: 216 PSERRSPERLKHYD---DHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRG 272

Query: 568 KQRSRHKSKDRYCEKDGE 585
           +  SRH+S +R  E++ E
Sbjct: 273 RTPSRHRSYERSRERERE 290


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.126    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,710,196
Number of Sequences: 37866
Number of extensions: 1125675
Number of successful extensions: 6839
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 258
Number of HSP's that attempted gapping in prelim test: 5153
Number of HSP's gapped (non-prelim): 1261
length of query: 605
length of database: 18,247,518
effective HSP length: 108
effective length of query: 497
effective length of database: 14,157,990
effective search space: 7036521030
effective search space used: 7036521030
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.