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Search of human proteins with 14589893
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
(916 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 1845 0.0
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 1243 0.0
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 712 0.0
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 616 e-176
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 603 e-172
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 482 e-136
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 447 e-125
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 446 e-125
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 446 e-125
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 434 e-121
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 429 e-120
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 422 e-118
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 421 e-117
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 419 e-117
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 410 e-114
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 401 e-111
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 397 e-110
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 396 e-110
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 388 e-107
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 388 e-107
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 387 e-107
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 381 e-105
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 376 e-104
gi|16753221 cadherin 22 precursor [Homo sapiens] 372 e-103
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens] 367 e-101
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 350 4e-96
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 346 6e-95
gi|116534898 desmoglein 2 preproprotein [Homo sapiens] 327 2e-89
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] 323 6e-88
gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens] 318 1e-86
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 1845 bits (4780), Expect = 0.0
Identities = 916/916 (100%), Positives = 916/916 (100%)
Query: 1 MTAGAGVLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFS 60
MTAGAGVLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFS
Sbjct: 1 MTAGAGVLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFS 60
Query: 61 SCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLL 120
SCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLL
Sbjct: 61 SCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLL 120
Query: 121 VAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPE 180
VAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPE
Sbjct: 121 VAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPE 180
Query: 181 NSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEH 240
NSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEH
Sbjct: 181 NSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEH 240
Query: 241 ASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVT 300
ASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVT
Sbjct: 241 ASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVT 300
Query: 301 ANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQ 360
ANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQ
Sbjct: 301 ANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQ 360
Query: 361 ATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQ 420
ATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQ
Sbjct: 361 ATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQ 420
Query: 421 PHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPL 480
PHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPL
Sbjct: 421 PHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPL 480
Query: 481 ASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQ 540
ASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQ
Sbjct: 481 ASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQ 540
Query: 541 AVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGT 600
AVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGT
Sbjct: 541 AVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGT 600
Query: 601 LQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRK 660
LQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRK
Sbjct: 601 LQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRK 660
Query: 661 NWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCT 720
NWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCT
Sbjct: 661 NWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCT 720
Query: 721 TIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNI 780
TIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNI
Sbjct: 721 TIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNI 780
Query: 781 LKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPG 840
LKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPG
Sbjct: 781 LKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPG 840
Query: 841 DIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWG 900
DIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWG
Sbjct: 841 DIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWG 900
Query: 901 PRFKKLADMYGGGEED 916
PRFKKLADMYGGGEED
Sbjct: 901 PRFKKLADMYGGGEED 916
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 1243 bits (3215), Expect = 0.0
Identities = 604/914 (66%), Positives = 737/914 (80%), Gaps = 15/914 (1%)
Query: 5 AGVLLLLLSLSGAL-RAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFSSCV 63
AG L LL L AL +A E CK GF ED Y+A++S+++ EG+ LL VKFS+C
Sbjct: 5 AGALRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLNVKFSNCN 64
Query: 64 GTKGTQYETNS-MDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVA 122
G + QYE++ DFKV DG V+A R + SE F + A D +T EKW V+L +
Sbjct: 65 GKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLK 124
Query: 123 QTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENS 182
T + S + + +++V P +++ L+R+KRDWVIPPIN+PENS
Sbjct: 125 PTLTEESVKESAEVEEIV------------FPRQFSKHSGHLQRQKRDWVIPPINLPENS 172
Query: 183 RGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHAS 242
RGPFPQ+LVRIRSD+D ++ +RYS+TG GADQPP +F I+ +SG++ VT+P+DRE+ A
Sbjct: 173 RGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIAR 232
Query: 243 YHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTAN 302
+HLRAHAVD+NGN+VENPID+ I VIDMNDNRPEF++QV+NG+V EGSKPGTYVMTVTA
Sbjct: 233 FHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAI 292
Query: 303 DADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQAT 362
DADD NGM+RYRIV+Q P +PS NMFTIN+ETGDI+TVAAGLDREKVQQYT+I+QAT
Sbjct: 293 DADDPNALNGMLRYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQAT 352
Query: 363 DMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPH 422
DMEGN YGLSNTATA+ITVTDVNDNPPEFTA TF GEVPENRV+ +VANLTV D+DQPH
Sbjct: 353 DMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPH 412
Query: 423 SPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLAS 482
+P WNAVYRI GDP+G F+++TDP +N+G+VTVVK +D+E NR F+LTV NQ PLA
Sbjct: 413 TPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAK 472
Query: 483 GIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAV 542
GIQ QSTA V+++++D+NE PYF N K+IR EEG+ GT+LTTF+A DPDR+MQQ +
Sbjct: 473 GIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNI 532
Query: 543 RYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQ 602
RY+KLSDPA+WL I+ NGQITT AVLDRES KNN+Y ATFLA+DNGIPP SGTGTLQ
Sbjct: 533 RYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQ 592
Query: 603 IYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNW 662
IYL+DINDNAP++LP+EA+ CE P+ N+INITA D D+DPN GP+ F+LP P +++NW
Sbjct: 593 IYLLDINDNAPQVLPQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNW 652
Query: 663 TITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTI 722
TITRLNGD+AQL+L+I +LEAG+Y+VPII+TDSGNPP SN SI++VKVC CD NGDCT +
Sbjct: 653 TITRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDV 712
Query: 723 GAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILK 782
+ AGLGTGAI+AIL+CI+ILL +VL+FV+WMKRR+KER KQLLIDPEDDVRDNILK
Sbjct: 713 DRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILK 772
Query: 783 YDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDI 842
YDEEGGGEEDQDYDLSQLQQP+ + K G+RR+DERP+ AEPQYP+R PHPGDI
Sbjct: 773 YDEEGGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRMDERPIHAEPQYPVRSAAPHPGDI 832
Query: 843 GDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSS-GDQDYDYLNDWGP 901
GDFINEGL+AADNDPTAPPYDSLLVFDYEGSGSTAGS+SSLNSSSS G+QDYDYLNDWGP
Sbjct: 833 GDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGP 892
Query: 902 RFKKLADMYGGGEE 915
RFKKLADMYGGG++
Sbjct: 893 RFKKLADMYGGGDD 906
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 712 bits (1838), Expect = 0.0
Identities = 419/916 (45%), Positives = 553/916 (60%), Gaps = 51/916 (5%)
Query: 8 LLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILE-GEKLLQVKFSSCVGTK 66
LLLLL +S L E C GF + YT + + LE G L +V F C G +
Sbjct: 11 LLLLLQVSSWL------CQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQ 64
Query: 67 GTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSS 126
T Y + FKVG DG + R L+ + Q+ F V AWDS T K+ V L T
Sbjct: 65 RTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDS-TYRKFSTKVTL---NTVG 120
Query: 127 PHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPF 186
H H+P + V+ + LL +P ++ GLRR+KRDWVIPPI+ PEN +GPF
Sbjct: 121 HH--HRPPPHQASVS-----GIQAELLTFPN--SSPGLRRQKRDWVIPPISCPENEKGPF 171
Query: 187 PQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLR 246
P+ LV+I+S+KD + + YSITG GAD PP+ VF I+ +G + VT P+DRE A+Y L
Sbjct: 172 PKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLF 231
Query: 247 AHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADD 306
+HAV NGN VE+P+++ I V D NDN+PEF +V+ GSV EG+ PGT VM VTA DADD
Sbjct: 232 SHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADD 291
Query: 307 S-TTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDME 365
T N + Y I++Q P+ P +NMFTIN TG I V GLDRE YT++VQA D++
Sbjct: 292 DVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQ 351
Query: 366 GNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPN 425
G GLS TATA+ITVTD NDNPP F +T+ G+VPEN V+ L V D D P++P
Sbjct: 352 GE---GLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPA 408
Query: 426 WNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQ 485
W AVY I++ D G F V T+PV N+G++ K +D+E + ++L V V+N P +
Sbjct: 409 WEAVYTILN-DDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLT 467
Query: 486 MSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYS 545
STA VT+ ++D+NEAP F K + + E G +T+++A +PD FM+Q + Y
Sbjct: 468 ---TSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYR 524
Query: 546 KLSDPASWLHINATNGQITTAAVLDRESL-YTKNNVYEATFLAADNGIPPASGTGTLQIY 604
D A+WL IN G I+T A LDRE + KN+ Y A +A DNG P A+GTGTL +
Sbjct: 525 IWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLI 584
Query: 605 LIDINDNAPELLPKEAQICEK-PNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWT 663
L D+NDNAP P+ CE+ P INI DAD+ PN P+ EL +A NWT
Sbjct: 585 LSDVNDNAPIPEPRTIFFCERNPKPQVINI--IDADLPPNTSPFTAELTHGASA---NWT 639
Query: 664 ITRLNGDYAQLSLR-ILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTI 722
I + + L+ + LE G Y + + + D+ N + ++V VC C+
Sbjct: 640 IQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNK--DQVTTLEVSVCDCEGAAGVCRK 697
Query: 723 GAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILK 782
AGL AI+ IL IL LL ++LL +++++RR K+ L+ PEDD RDN+
Sbjct: 698 AQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAV---VKEPLLPPEDDTRDNVYY 754
Query: 783 YDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERP-VGAEPQYPIRPMVPHPGD 841
YDEEGGGEEDQD+DLSQL + P V R D P + + P+Y RP +P +
Sbjct: 755 YDEEGGGEEDQDFDLSQLHRG------LDARPEVTRNDVAPTLMSVPRYLPRP--ANPDE 806
Query: 842 IGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSG-DQDYDYLNDWG 900
IG+FI+E L+AAD DPTAPPYDSLLVFDYEGSGS A S+SSLNSS S DQDYDYLN+WG
Sbjct: 807 IGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWG 866
Query: 901 PRFKKLADMYGGGEED 916
RFKKLADMYGGGE+D
Sbjct: 867 NRFKKLADMYGGGEDD 882
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 616 bits (1588), Expect = e-176
Identities = 344/762 (45%), Positives = 469/762 (61%), Gaps = 43/762 (5%)
Query: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSID 223
LRR KRDWV+ PI+VPEN +GPFPQ+L +++S+KD D I YSITG GAD PP VF+++
Sbjct: 102 LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVE 161
Query: 224 SMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYN 283
+G + + +P+DREE A Y L HAV NG VE+P+++ I V D ND++P+F +
Sbjct: 162 KETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFR 221
Query: 284 GSVDEGSKPGTYVMTVTANDADDST-TANGMVRYRIVTQTPQSPSQNMFTINSETGDIVT 342
GSV EG PGT VM VTA D DD+ T NG+V Y I +Q P+ P MFTI+ TG I
Sbjct: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
Query: 343 VAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVP 402
+++GLDREKV +YT+ +QATDM+G+ G + TA A++ + D NDN P F + VP
Sbjct: 282 ISSGLDREKVPEYTLTIQATDMDGD---GSTTTAVAVVEILDANDNAPMFDPQKYEAHVP 338
Query: 403 ENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDY 462
EN V V LTV D D P+SP W A Y I+ GD HF++ T P +N+G++T K +D+
Sbjct: 339 ENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDF 398
Query: 463 ELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPP 522
E L V V+N+AP + STA + + + D+NEAP F K++ ++EG+P
Sbjct: 399 EAKNQHTLYVEVTNEAPFVLKLP---TSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPT 455
Query: 523 GTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRE-SLYTKNNVY 581
G + ++A DPD+ Q + Y L DPA WL ++ +GQ+T LDRE + +NN+Y
Sbjct: 456 GEPVCVYTAEDPDK-ENQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIY 514
Query: 582 EATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQIC-EKPNLNAINITAADADV 640
E LA DNG PP +GTGTL + LID+ND+ P P++ IC + P +NIT D D+
Sbjct: 515 EVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNIT--DKDL 572
Query: 641 DPNIGPYVFELPFVPAAVRKNWTI-TRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPP 699
P+ P+ +L WT GD LSL+ +L+ YDV + ++D GN
Sbjct: 573 SPHTSPFQAQLTDDSDIY---WTAEVNEEGDTVVLSLK-KFLKQDTYDVHLSLSDHGNK- 627
Query: 700 LSNTSIIKVKVCPCDDNGDCTTIGAVAAAGL---GTGAIVAILICILILLTMVLLFVMWM 756
++I+ VC C +G T G GA++A+L +L+LL +V
Sbjct: 628 -EQLTVIRATVCDC--HGHVETCPGPWKGGFILPVLGAVLALLFLLLVLLLLV------- 677
Query: 757 KRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGV 816
K+R K+ L+ PEDD RDN+ Y EEGGGEEDQDYD++QL + + ++ V
Sbjct: 678 ---RKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHR-----GLEARPEVV 729
Query: 817 RRVDERP-VGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGS 875
R D P + P Y RP +P +IG+FI E L+AA+ DPTAPPYD+LLVFDYEGSGS
Sbjct: 730 LRNDVAPTIIPTPMY--RPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGS 787
Query: 876 TAGSVSSLNSSSSG-DQDYDYLNDWGPRFKKLADMYGGGEED 916
A S+SSL SS+S DQDYDYLN+WG RFKKLADMYGGGE+D
Sbjct: 788 DAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD 829
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 603 bits (1554), Expect = e-172
Identities = 343/769 (44%), Positives = 465/769 (60%), Gaps = 25/769 (3%)
Query: 151 TLLPWPQHQNANGLRRRKRDWVIPPINVPEN-SRGPFPQQLVRIRSDKDNDIPIRYSITG 209
TL PW + A L R +R WVIPPI+V EN R P+P LV+I+SDK + YSI G
Sbjct: 30 TLYPW---RRAPALSRVRRAWVIPPISVSENHKRLPYP--LVQIKSDKQQLGSVIYSIQG 84
Query: 210 VGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVID 269
G D+ P VFSID +G++++ +DRE+ + LRA A+D+ G+ +E+P DL I V+D
Sbjct: 85 PGVDEEPRGVFSIDKFTGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVD 144
Query: 270 MNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQN 329
NDNRP F+ + + G V EG+ PGTYV A DADD T N +R+ I+ Q S
Sbjct: 145 QNDNRPAFLQEAFTGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSIL----QQGSPE 200
Query: 330 MFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNP 389
+F+I+ TG+I TV GLDRE V Y + +Q DM G+ GL+ TA+AIIT+ D+NDN
Sbjct: 201 LFSIDELTGEIRTVQVGLDREVVAVYNLTLQVADMSGD---GLTATASAIITLDDINDNA 257
Query: 390 PEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVT 449
PEFT F E E V L V DRD P SPNW A + I+ GDP G F++RTDP T
Sbjct: 258 PEFTRDEFFMEAIEAVSGVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKT 317
Query: 450 NEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPS 509
NEG++++VKA+DYE + L V V N+APL + + + A V + + D NE P F
Sbjct: 318 NEGVLSIVKALDYESCEHYELKVSVQNEAPLQAAALRAERGQAKVRVHVQDTNEPPVFQE 377
Query: 510 NHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVL 569
N L EG PPGT++ TFSA DPD Q + YSK DP WL ++A G+I T VL
Sbjct: 378 NPLRTSLAEGAPPGTLVATFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVL 437
Query: 570 DRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELL-PKEAQICEKPNL 628
S + K Y A LA D+ P + TGTL I ++++ND+AP L P +C +P+
Sbjct: 438 SPASPFLKGGWYRAIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQ 497
Query: 629 N-AINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYD 687
+ + A D D+ P+ P+ F+L + +NW+++++N +A+L R E G++
Sbjct: 498 GPGLLLGATDEDLPPHGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPRHQVPE-GLHR 556
Query: 688 VPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAA---GLGTGAIVAILICILI 744
+ +++ DSG PP + V VC C +G C A A GL GA+V +L L+
Sbjct: 557 LSLLLRDSGQPPQQREQPLNVTVCRCGKDGVCLPGAAALLAGGTGLSLGALVIVLASALL 616
Query: 745 LLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQP 803
LL +VLL V R K+ K LL P+DD+RDN+L YDE+GGGEEDQD YD+SQL+ P
Sbjct: 617 LLVLVLL-VALRARFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEEDQDAYDISQLRHP 675
Query: 804 EAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYD 863
A+ +P P +RR + P G P R + P DI DFIN+GL AAD+DP+ PPYD
Sbjct: 676 TALS-LPLGPPPLRR--DAPQGRLHPQPPRVLPTSPLDIADFINDGLEAADSDPSVPPYD 732
Query: 864 SLLVFDYEGSGSTAGSVSS-LNSSSSGDQDYDYLNDWGPRFKKLADMYG 911
+ L++DYEG GS AG++SS L+S DQDYDYL DWGPRF +LADMYG
Sbjct: 733 TALIYDYEGDGSVAGTLSSILSSQGDEDQDYDYLRDWGPRFARLADMYG 781
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 482 bits (1240), Expect = e-136
Identities = 288/725 (39%), Positives = 407/725 (56%), Gaps = 43/725 (5%)
Query: 7 VLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFSSCVGTK 66
VL +LLS L EDL C GF + + +E + +L + FS C G
Sbjct: 8 VLCVLLS-QVLLLTSAEDLD----CTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGND 62
Query: 67 GTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSS 126
+YE +S FKV +DG + A R + AV + L +
Sbjct: 63 KLRYEVSSPYFKVNSDGGLVALRNIT----------------------AVGKTLFVHART 100
Query: 127 PHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPF 186
PH+ + + + + +L + + + R+KR V+ PI +PEN R PF
Sbjct: 101 PHAEDMAE-----LVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPF 155
Query: 187 PQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLR 246
P+ + ++ D D ++ +TG G DQ P +F I+ +G + VTR +DRE A Y L
Sbjct: 156 PRDVGKV-VDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLF 214
Query: 247 AHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADD 306
D+NG +E P+ L + VID NDNRP F Y G V EGS GT VM +TA DADD
Sbjct: 215 VETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADD 274
Query: 307 STTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVA--AGLDREKVQ--QYTVIVQAT 362
T N ++RY I QTP PS NMF I+ E GDIVTV A LDRE ++ +Y +I++A
Sbjct: 275 PATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQ 334
Query: 363 DMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPH 422
DM G L+ GL+ TATA I + D ND+ P+FT F V E V +V NLTV D+D P
Sbjct: 335 DMAG-LDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIV-NLTVEDKDDPT 392
Query: 423 SPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLAS 482
+ W A Y II+G+P F + T+P TNEGM++VVK +DYE++ L + V N+ PL
Sbjct: 393 TGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVP 452
Query: 483 GIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAV 542
+ STA V I+++D+NE P F + ++ +E + G+VL T +A DPD Q +
Sbjct: 453 DVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTI 512
Query: 543 RYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQ 602
RYS DPA WL+IN NG + T AVLDRES + N+VY A FLA D+G PPA+GTGTL
Sbjct: 513 RYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLL 572
Query: 603 IYLIDINDNAPELLPKEAQIC-EKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKN 661
I L D+NDNAP + P A++C + NL+ + + A+D D+ PN P+ FE+ A K
Sbjct: 573 ITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEI-HKQAVPDKV 631
Query: 662 WTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPC-DDNGDCT 720
W I+++N +A +SL + L Y++PI+VTDSG PP++N + ++V+VC C + DC
Sbjct: 632 WKISKINNTHALVSL-LQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCN 690
Query: 721 TIGAV 725
GA+
Sbjct: 691 AAGAL 695
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 447 bits (1150), Expect = e-125
Identities = 303/774 (39%), Positives = 430/774 (55%), Gaps = 60/774 (7%)
Query: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSI 222
L+R KR WV V E GP P + R+ SD D+ D I+Y ++G GA +F I
Sbjct: 48 LQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGT----IFVI 103
Query: 223 DSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFINQV 281
D SG ++ T+ +DREE A Y L A AVD + N+ +E P + + V D+NDN PEF+++
Sbjct: 104 DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHET 163
Query: 282 YNGSVDEGSKPGTYVMTVTANDADDSTTANGM-VRYRIVTQTPQSPSQNMFTINSETGDI 340
Y+ +V E S GT V+ VTA+DADD T N + Y I+ P F++ ++TG I
Sbjct: 164 YHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPY------FSVEAQTGII 217
Query: 341 VTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGE 400
T +DRE ++Y V++QA DM G++ GLS T IT+TDVNDNPP+F S +
Sbjct: 218 RTALPNMDREAKEEYHVVIQAKDMGGHMG-GLSGTTKVTITLTDVNDNPPKFPQSVYQMS 276
Query: 401 VPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAV 460
V E V V +D N Y I+ GD F + TD T EG++ + K V
Sbjct: 277 VSEAAVPGEEVG-RVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPV 335
Query: 461 DYELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRLEEG 519
D+E RA+ L V +N I F+ T V IS+ D +E P F + + ++E
Sbjct: 336 DFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQEN 395
Query: 520 VPPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESLYTK 577
GTV+ A DPD +RYS + +D + IN +G I T LDRE
Sbjct: 396 AAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWL 454
Query: 578 NNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELL-PKEAQICE----KP--NLNA 630
N T AA+ + I ++D+NDNAP+ P E ICE KP N
Sbjct: 455 N----ITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPI 510
Query: 631 INITAADADVDPNIGPYVFELPFVPAAVRK-NWTITRLNGDYAQLSLR---ILYLEAGMY 686
+ I+A D D N ++F LP P + N+T+ + A + R + +Y
Sbjct: 511 VTISADDKDDTANGPRFIFSLP--PEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLY 568
Query: 687 DVPIIVTDSGNPPLSNTSIIKVKVCPCDDNG---DCTTIGAVAAAGLGTGAIVAILICIL 743
+PI+++D G PP+S+T+ + +KVC CD NG C + AGL TGA++AIL CI+
Sbjct: 569 LLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIV 628
Query: 744 ILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQ 802
ILL +V+LFV ++R++KE L++ E+DVR+NI+ YD+EGGGEED + +D++ LQ
Sbjct: 629 ILLVIVVLFVT-LRRQKKE----PLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQN 683
Query: 803 PEAM-GHVPSKAPGVRRVDERPVGAEPQYPIRPMV---PHPGDIGDFINEGLRAADNDPT 858
P+ + G +P K D +P E QY RP + P+ D+ DFIN ++ ADNDPT
Sbjct: 684 PDGINGFIPRK-------DIKP---EYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPT 733
Query: 859 APPYDSLLVFDYEGSGSTAGSVSSLNSSSS-GDQDYDYLNDWGPRFKKLADMYG 911
APPYDS+ ++ YEG GS AGS+SSL S+++ D DYDYL +WGPRFKKLAD+YG
Sbjct: 734 APPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLYG 787
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 446 bits (1147), Expect = e-125
Identities = 298/774 (38%), Positives = 427/774 (55%), Gaps = 52/774 (6%)
Query: 162 NGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVF 220
+G R KR WV V E G P + ++ SD D D I+Y ++G GA +F
Sbjct: 40 SGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASS----IF 95
Query: 221 SIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFIN 279
ID +G ++ T+ +DREE A Y LRA A+D NK VE + I + D+NDN P+F++
Sbjct: 96 IIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLD 155
Query: 280 QVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGD 339
Y V E S GT V+ VTA DADD T N R+V Q Q F++ +TG
Sbjct: 156 GPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSA---RVVYSILQG--QPYFSVEPKTGV 210
Query: 340 IVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAG 399
I T +DRE QY +++QA DM G N GLS T + +T+TDVNDNPP F ++
Sbjct: 211 IKTALPNMDREAKDQYLLVIQAKDMVGQ-NGGLSGTTSVTVTLTDVNDNPPRFPRRSYQY 269
Query: 400 EVPENR-VETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVK 458
VPE+ V +VVA + D D N Y+I+ GD G F + D T EG++T+ K
Sbjct: 270 NVPESLPVASVVARIKAADADI--GANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQK 327
Query: 459 AVDYELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRLE 517
+D+E ++ L + +N+ + + F T V I + D++E P F S + +
Sbjct: 328 ELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVS 387
Query: 518 EGVPPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESLY 575
E G ++ T +A DPD VRYS + +D + +I+A +G ITTA LDRE+
Sbjct: 388 EATQVGNIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET-- 444
Query: 576 TKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPEL-LPKEAQICE--KPNLNAIN 632
N ++ T LA ++ P G G + I ++DINDNAPE + E +CE +P
Sbjct: 445 --NAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQK 502
Query: 633 ITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLR---ILYLEAGMYDVP 689
I+A D D N + F L A N+++ + A + R E +Y +P
Sbjct: 503 ISAVDKDEPSNGHQFYFSLT-TDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLP 561
Query: 690 IIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGA---VAAAGLGTGAIVAILICILILL 746
I + DSG+P LS+T+ + ++VC CD +G T A V AGL TGA++AIL C+L LL
Sbjct: 562 IFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLL 621
Query: 747 TMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPEA 805
++LL V M+RR+KE L+ D E D+R+NI++YD+EGGGEED + +D++ L+
Sbjct: 622 VLILLIVT-MRRRKKE----PLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNV 676
Query: 806 MGHVPSKAPGVRRVDERPVGAEPQYPIRPM---VPHPGDIGDFINEGLRAADNDPTAPPY 862
+ ++ R V E Q+ RP +P +FI E L+ AD DP APPY
Sbjct: 677 IRDTKTR---------RDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADVDPGAPPY 727
Query: 863 DSLLVFDYEGSGSTAGSVSSLNS-SSSGDQDYDYLNDWGPRFKKLADMYGGGEE 915
DSL + +EG+GS A S+SSL+S SS+ DQ+YDYL+DWGPRFK+LADMYG G+E
Sbjct: 728 DSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQE 781
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 446 bits (1147), Expect = e-125
Identities = 298/774 (38%), Positives = 427/774 (55%), Gaps = 52/774 (6%)
Query: 162 NGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVF 220
+G R KR WV V E G P + ++ SD D D I+Y ++G GA +F
Sbjct: 40 SGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASS----IF 95
Query: 221 SIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFIN 279
ID +G ++ T+ +DREE A Y LRA A+D NK VE + I + D+NDN P+F++
Sbjct: 96 IIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLD 155
Query: 280 QVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGD 339
Y V E S GT V+ VTA DADD T N R+V Q Q F++ +TG
Sbjct: 156 GPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSA---RVVYSILQG--QPYFSVEPKTGV 210
Query: 340 IVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAG 399
I T +DRE QY +++QA DM G N GLS T + +T+TDVNDNPP F ++
Sbjct: 211 IKTALPNMDREAKDQYLLVIQAKDMVGQ-NGGLSGTTSVTVTLTDVNDNPPRFPRRSYQY 269
Query: 400 EVPENR-VETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVK 458
VPE+ V +VVA + D D N Y+I+ GD G F + D T EG++T+ K
Sbjct: 270 NVPESLPVASVVARIKAADADI--GANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQK 327
Query: 459 AVDYELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRLE 517
+D+E ++ L + +N+ + + F T V I + D++E P F S + +
Sbjct: 328 ELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVS 387
Query: 518 EGVPPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESLY 575
E G ++ T +A DPD VRYS + +D + +I+A +G ITTA LDRE+
Sbjct: 388 EATQVGNIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET-- 444
Query: 576 TKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPEL-LPKEAQICE--KPNLNAIN 632
N ++ T LA ++ P G G + I ++DINDNAPE + E +CE +P
Sbjct: 445 --NAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQK 502
Query: 633 ITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLR---ILYLEAGMYDVP 689
I+A D D N + F L A N+++ + A + R E +Y +P
Sbjct: 503 ISAVDKDEPSNGHQFYFSLT-TDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLP 561
Query: 690 IIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGA---VAAAGLGTGAIVAILICILILL 746
I + DSG+P LS+T+ + ++VC CD +G T A V AGL TGA++AIL C+L LL
Sbjct: 562 IFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLL 621
Query: 747 TMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPEA 805
++LL V M+RR+KE L+ D E D+R+NI++YD+EGGGEED + +D++ L+
Sbjct: 622 VLILLIVT-MRRRKKE----PLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNV 676
Query: 806 MGHVPSKAPGVRRVDERPVGAEPQYPIRPM---VPHPGDIGDFINEGLRAADNDPTAPPY 862
+ ++ R V E Q+ RP +P +FI E L+ AD DP APPY
Sbjct: 677 IRDTKTR---------RDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADVDPGAPPY 727
Query: 863 DSLLVFDYEGSGSTAGSVSSLNS-SSSGDQDYDYLNDWGPRFKKLADMYGGGEE 915
DSL + +EG+GS A S+SSL+S SS+ DQ+YDYL+DWGPRFK+LADMYG G+E
Sbjct: 728 DSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQE 781
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 434 bits (1115), Expect = e-121
Identities = 301/778 (38%), Positives = 433/778 (55%), Gaps = 62/778 (7%)
Query: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKD-NDIPIRYSITGVGADQPPMEVFSI 222
L R KR WV + V E GP P + R+ +D D I+Y ++G GA +F I
Sbjct: 56 LNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGT----IFQI 111
Query: 223 DSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFINQV 281
+ ++G ++ + +DREE A Y L A AVD +K +E P + I V D+NDN PEF+N
Sbjct: 112 NDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGP 171
Query: 282 YNGSVDEGSKPGTYVMTVTANDADDSTTANGM-VRYRIVTQTPQSPSQNMFTINSETGDI 340
Y+ +V E S GT V VTA DADD N + Y I+ P F+I ET I
Sbjct: 172 YHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPY------FSIEPETAII 225
Query: 341 VTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGE 400
T +DRE ++Y V++QA DM G+ GLS T T +T+TDVNDNPP+F S +
Sbjct: 226 KTALPNMDREAKEEYLVVIQAKDMGGHSG-GLSGTTTLTVTLTDVNDNPPKFAQSLYHFS 284
Query: 401 VPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAV 460
VPE+ V V DQ N + Y II GD + F + +D +G++ + K +
Sbjct: 285 VPEDVVLGTAIG-RVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGIIRLRKPL 343
Query: 461 DYELNRAFMLTVMVSNQA--PLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEE 518
D+E +++ L V +N P SG + F+ TA V I + D +E P F S L+ + E
Sbjct: 344 DFETKKSYTLKVEAANVHIDPRFSG-RGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHE 402
Query: 519 GVPPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESLYT 576
+V+ +A DPD +R+S + +D +INA +G+IT A LDRE
Sbjct: 403 NAALNSVIGQVTARDPD-ITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVW 461
Query: 577 KNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPK-EAQICE--KPNLNAINI 633
N AT + + I + I ++D+NDNAPE + EA +CE KP +
Sbjct: 462 HNITIIATEIRNHSQISRVP----VAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTV 517
Query: 634 TAADADVDPNIGPYVFELPFVPAAVRK-NWTITRLNGDYAQLSLRILYLEAG-------M 685
+A D D DP G Y F +P V N+TI + + SL IL G +
Sbjct: 518 SAMDKD-DPKNGHY-FLYSLLPEMVNNPNFTIKKNEDN----SLSILAKHNGFNRQKQEV 571
Query: 686 YDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNG---DCTTIGAVAAAGLGTGAIVAILICI 742
Y +PII++DSGNPPLS+TS + ++VC C ++G C V GL GA++AIL CI
Sbjct: 572 YLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACI 631
Query: 743 LILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQ 801
++LL +V+LFV ++R + E L+I ++DVR+NI++YD+EGGGEED + +D++ LQ
Sbjct: 632 ILLLVIVVLFVT-LRRHKNE----PLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQ 686
Query: 802 QPEAM-GHVPSKAPGVRRVDERP-VGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTA 859
P+ + G +P K D +P + P+ + P VP+ D+ +FIN L ADNDPTA
Sbjct: 687 NPDGINGFLPRK-------DIKPDLQFMPRQGLAP-VPNGVDVDEFINVRLHEADNDPTA 738
Query: 860 PPYDSLLVFDYEGSGSTAGSVSSLNSSSS-GDQDYDYLNDWGPRFKKLADMYGGGEED 916
PPYDS+ ++ YEG GS AGS+SSL S++S DQ++DYL+DWGPRFK+L ++Y GE D
Sbjct: 739 PPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGESD 796
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 429 bits (1102), Expect = e-120
Identities = 290/774 (37%), Positives = 415/774 (53%), Gaps = 51/774 (6%)
Query: 162 NGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVF 220
N L R KR W+ + E G Q + ++ SD+D D ++Y ++G GA ++F
Sbjct: 46 NELNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAG----DLF 101
Query: 221 SIDSMSGRMYVTRPMDREEHASYHLRAHAVDMN-GNKVENPIDLYIYVIDMNDNRPEFIN 279
I+ +G + T+ +DREE Y LRA A++ G VE + I + D+NDN P F
Sbjct: 102 IINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTK 161
Query: 280 QVYNGSVDEGSKPGTYVMTVTANDADDSTTANGM-VRYRIVTQTPQSPSQNMFTINSETG 338
+VY +V E S GT+V+ VTA DADD T N V Y I+ P F++ SETG
Sbjct: 162 EVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPY------FSVESETG 215
Query: 339 DIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFA 398
I T +DRE +QY V++QA DM G + GLS T T IT+TDVNDNPP F ST+
Sbjct: 216 IIKTALLNMDRENREQYQVVIQAKDMGGQMG-GLSGTTTVNITLTDVNDNPPRFPQSTYQ 274
Query: 399 GEVPENRVE-TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVV 457
+ PE+ T + + D D N Y I G+ F V TD T EG++TV
Sbjct: 275 FKTPESSPPGTPIGRIKASDADV--GENAEIEYSITDGEGLDMFDVITDQETQEGIITVK 332
Query: 458 KAVDYELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRL 516
K +D+E + + L V SN + + F+ +A V I + D++E P F ++++
Sbjct: 333 KLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQI 392
Query: 517 EEGVPPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESL 574
E T + + +A DPD + V+YS + +D +I++ NG I T+ +LDRE+L
Sbjct: 393 REDAQINTTIGSVTAQDPDA-ARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETL 451
Query: 575 YTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLP-KEAQICEKPNLNAINI 633
N T +A + P S L I ++D+NDNAPE E +CEK + +
Sbjct: 452 LWHN----ITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQ 507
Query: 634 TAADADVDPNIGPYVFELPFVP-AAVRKNWTITRLNGDYAQLSLR---ILYLEAGMYDVP 689
T D D + F P AA N+TI + A + R E Y +P
Sbjct: 508 TLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLP 567
Query: 690 IIVTDSGNPPLSNTSIIKVKVCPCDDNGD---CTTIGAVAAAGLGTGAIVAILICILILL 746
++++D+ P S+T + V+VC CD +G+ C + GL TGA+VAIL+CI+ILL
Sbjct: 568 VVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVAILLCIVILL 627
Query: 747 TMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPEA 805
V+LF ++R+KE LI ++D+RDNI+ Y++EGGGEED Q +D+ L+ PEA
Sbjct: 628 VTVVLFAALRRQRKKEP-----LIISKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPEA 682
Query: 806 MGHVPSKAPGVRRVDERPVGAEPQYPIR--PMVPHPGDIGDFINEGLRAADNDPTAPPYD 863
+ + R + E + R P D+ DFIN+ L+ D DPTAPPYD
Sbjct: 683 IEDNKLR---------RDIVPEALFLPRRTPTARDNTDVRDFINQRLKENDTDPTAPPYD 733
Query: 864 SLLVFDYEGSGSTAGSVSSLNS-SSSGDQDYDYLNDWGPRFKKLADMYGGGEED 916
SL + YEG+GS A S+SSL S ++ DQDYDYL+DWGPRFKKLADMYGG + D
Sbjct: 734 SLATYAYEGTGSVADSLSSLESVTTDADQDYDYLSDWGPRFKKLADMYGGVDSD 787
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 422 bits (1084), Expect = e-118
Identities = 289/772 (37%), Positives = 420/772 (54%), Gaps = 54/772 (6%)
Query: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSI 222
L R+KR W+ + E G Q + ++ SD+D D ++Y ++G GA +F I
Sbjct: 49 LHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGT----LFII 104
Query: 223 DSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFINQV 281
D +G ++ TR +DREE A Y LRA A++ + VE + I + D+NDN P F ++
Sbjct: 105 DEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEI 164
Query: 282 YNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIV 341
Y SV E S GT V+ VTA DADD + N R++ Q Q F++ ETG I
Sbjct: 165 YTASVPEMSVVGTSVVQVTATDADDPSYGNSA---RVIYSILQG--QPYFSVEPETGIIR 219
Query: 342 TVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEV 401
T ++RE +QY V++QA DM G + GLS T T IT+TDVNDNPP F +T V
Sbjct: 220 TALPNMNRENREQYQVVIQAKDMGGQMG-GLSGTTTVNITLTDVNDNPPRFPQNTIHLRV 278
Query: 402 PENR-VETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAV 460
E+ V T + ++ D D N YRII GD + F + T+ T EG++TV K +
Sbjct: 279 LESSPVGTAIGSVKATDADT--GKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPL 336
Query: 461 DYELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRLEEG 519
DYE R + L V N + F+ T V ISI D++E P F + L + E
Sbjct: 337 DYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHED 396
Query: 520 VPPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESLYTK 577
+ GT++ T A DPD + +R+S + +D +I++ NG + T+ LDRE
Sbjct: 397 IEVGTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWH 455
Query: 578 NNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLP-KEAQICE--KPNLNAINIT 634
N T +AA+ P + + + ++D+NDNAP+ + +CE +P I+
Sbjct: 456 N----LTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTIS 511
Query: 635 AADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLR---ILYLEAGMYDVPII 691
A D D DP G F F AAV N+T+ + A++ R E Y +P++
Sbjct: 512 AVDKD-DPLGGQKFF---FSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVV 567
Query: 692 VTDSGNPPLSNTSIIKVKVCPCDDNGD---CTTIGAVAAAGLGTGAIVAILICILILLTM 748
++D+ P S+T + ++VC CD G+ C+ + AGL TGA++AIL+CI+ILL +
Sbjct: 568 ISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVI 627
Query: 749 VLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPEAMG 807
V+LF ++R+KE LI ++D+RDNI+ Y++EGGGEED Q +D+ L+ P A+
Sbjct: 628 VVLFAALKRQRKKEP-----LILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIE 682
Query: 808 HVPSKAPGVRRVDERPVGAEPQYPIR--PMVPHPGDIGDFINEGLRAADNDPTAPPYDSL 865
+ R + E + R P P D+ DFINE L+ D DPTAPPYDSL
Sbjct: 683 EKKLR---------RDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSL 733
Query: 866 LVFDYEGSGSTAGSVSSLNS-SSSGDQDYDYLNDWGPRFKKLADMYGGGEED 916
+ YEG+ S A S+SSL S ++ GDQ+YDYL +WGPRF KLA+MYGGGE D
Sbjct: 734 ATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESD 785
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 421 bits (1081), Expect = e-117
Identities = 295/773 (38%), Positives = 417/773 (53%), Gaps = 53/773 (6%)
Query: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSI 222
LRR KR W+ + E G Q + ++ +D+D D ++Y +TG GA +F I
Sbjct: 48 LRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGS----LFVI 103
Query: 223 DSMSGRMYVTRPMDREEHASYHLRAHAVDMN-GNKVENPIDLYIYVIDMNDNRPEFINQV 281
D +G ++ + +DREE + Y LRA A+D G +VE + I + D+NDN P+F +
Sbjct: 104 DENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDL 163
Query: 282 YNGSVDEGSKPGTYVMTVTANDADDSTTANGM-VRYRIVTQTPQSPSQNMFTINSETGDI 340
Y SV E S GT V+ VTA DADD+ N V Y I+ P F+++ E+G I
Sbjct: 164 YTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPY------FSVDPESGII 217
Query: 341 VTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGE 400
T + RE +QY V++QA DM G + GLS T T IT+TDVN+NPP F ST+
Sbjct: 218 KTALPDMSRENREQYQVVIQAKDMGGQMG-GLSGTTTVNITLTDVNNNPPRFPQSTYQFN 276
Query: 401 VPEN-RVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKA 459
PE+ + T + + D D N Y I GD + F V TD T EG++TV +
Sbjct: 277 SPESVPLGTHLGRIKANDPDV--GENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQN 334
Query: 460 VDYELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRLEE 518
+D+E + L V SN P + + F+ TA V IS+ DI+E P F LI ++E
Sbjct: 335 LDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDE 394
Query: 519 GVPPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESLYT 576
V G+++ +A DPD ++YS + +D I++ NG I T LDRES
Sbjct: 395 DVKEGSIIGQVTAYDPDA-RNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPW 453
Query: 577 KNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPEL-LPKEAQICE--KPNLNAINI 633
N T A + P S + I ++DIND+APE + E +CE KP +
Sbjct: 454 HN----ITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTV 509
Query: 634 TAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLR---ILYLEAGMYDVPI 690
+ D D P + FE P + N+TI + A + R + Y +PI
Sbjct: 510 SVMDKDDPPRGHKFFFE-PVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPI 568
Query: 691 IVTDSGNPPLSNTSIIKVKVCPCDDNGD---CTTIGAVAAAGLGTGAIVAILICILILLT 747
++ D+ P S+T + ++VC CD+ G+ CT + +AGL TGA+VAIL+C+LILL
Sbjct: 569 LIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLI 628
Query: 748 MVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPEAM 806
+V+LF ++R+KE LI +DDVRDNI+ Y++EGGGEED Q +D+ L+ PEA
Sbjct: 629 LVVLFAALKRQRKKEP-----LIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEA- 682
Query: 807 GHVPSKAPGVRRVDERPVGAEPQYPIRPMVP--HPGDIGDFINEGLRAADNDPTAPPYDS 864
SK R V E + IR VP D+ DFI+ L+ D DP+APPYDS
Sbjct: 683 -REDSKL-------RRDVMPETIFQIRRTVPLWENIDVQDFIHRRLKENDADPSAPPYDS 734
Query: 865 LLVFDYEGSGSTAGSVSSLNSSSSG-DQDYDYLNDWGPRFKKLADMYGGGEED 916
L + YEG+ S A S+SSL S ++ +QDYDYL+DWGPRFKKLADMYGG + D
Sbjct: 735 LATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYGGDDSD 787
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 419 bits (1077), Expect = e-117
Identities = 290/793 (36%), Positives = 428/793 (53%), Gaps = 55/793 (6%)
Query: 146 PPPKDTLLPWPQHQ------NANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN 199
P P+ TL P+ + +R KR WV V E G PQ + ++ SD D
Sbjct: 25 PQPQQTLATEPRENVIHLPGQRSHFQRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDK 84
Query: 200 -DIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-V 257
+ ++Y+++G GA VF+ID +G ++ R +DREE Y LRA AVD+ K +
Sbjct: 85 GEGTVKYTLSGDGAGT----VFTIDETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPL 140
Query: 258 ENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYR 317
E + I V D+NDN P+F++ Y +V E S G YV+ V A DADD T N R
Sbjct: 141 EPESEFIIKVQDINDNEPKFLDGPYVATVPEMSPVGAYVLQVKATDADDPTYGNSA---R 197
Query: 318 IVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTAT 377
+V Q Q F+I+ +TG I T +DRE +QY V++QA DM G L GL+ T
Sbjct: 198 VVYSILQG--QPYFSIDPKTGVIRTALPNMDREVKEQYQVLIQAKDMGGQLG-GLAGTTI 254
Query: 378 AIITVTDVNDNPPEFTASTFAGEVPENR-VETVVANLTVMDRDQPHSPNWNAVYRIISGD 436
IT+TDVNDNPP F S F +VPE+ + + + + +D D N Y I+ GD
Sbjct: 255 VNITLTDVNDNPPRFPKSIFHLKVPESSPIGSAIGRIRAVDPD--FGQNAEIEYNIVPGD 312
Query: 437 PSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMS--FQSTAGV 494
F + TD T EG++ + K +D+E +A+ V SN L + F+ TA V
Sbjct: 313 GGNLFDIVTDEDTQEGVIKLKKPLDFETKKAYTFKVEASN-LHLDHRFHSAGPFKDTATV 371
Query: 495 TISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRY--SKLSDPAS 552
IS++D++E P F + + E P GT++ +A D D AVRY SD S
Sbjct: 372 KISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLD-VGSSAVRYFIDWKSDGDS 430
Query: 553 WLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNA 612
+ I+ G I T +LDRES Y + +A+ P + + I ++D+N+
Sbjct: 431 YFTIDGNEGTIATNELLDRESTAQ----YNFSIIASKVSNPLLTSKVNILINVLDVNEFP 486
Query: 613 PEL-LPKEAQICE--KPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNG 669
PE+ +P E +CE KP ++AAD D+ P + F L AA++ N+T+
Sbjct: 487 PEISVPYETAVCENAKPGQIIQIVSAADRDLSPAGQQFSFRLS-PEAAIKPNFTVRDFRN 545
Query: 670 DYAQLSLR---ILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNG---DCTTIG 723
+ A + R + +Y +P+++ DS P S+T+ + ++VC CD +G C
Sbjct: 546 NTAGIETRRNGYSRRQQELYFLPVVIEDSSYPVQSSTNTMTIRVCRCDSDGTILSCNVEA 605
Query: 724 AVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKY 783
GL TGA++AIL+CI+ILL +V+L+V RR+K++ T L+ ++D+RDN++ Y
Sbjct: 606 IFLPVGLSTGALIAILLCIVILLAIVVLYVAL--RRQKKKDT---LMTSKEDIRDNVIHY 660
Query: 784 DEEGGGEED-QDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDI 842
D+EGGGEED Q +D+ L+ P+ + + +RR + P+ RP + DI
Sbjct: 661 DDEGGGEEDTQAFDIGALRNPKVI-----EENKIRRDIKPDSLCLPRQ--RPPMEDNTDI 713
Query: 843 GDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNS-SSSGDQDYDYLNDWGP 901
DFI++ L+ D DPTAPPYDSL + YEGSGS A S+SS++S ++ DQDYDYL DWGP
Sbjct: 714 RDFIHQRLQENDVDPTAPPYDSLATYAYEGSGSVAESLSSIDSLTTEADQDYDYLTDWGP 773
Query: 902 RFKKLADMYGGGE 914
RFK LADM+G E
Sbjct: 774 RFKVLADMFGEEE 786
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 410 bits (1053), Expect = e-114
Identities = 276/896 (30%), Positives = 447/896 (49%), Gaps = 83/896 (9%)
Query: 49 LEGEKLL-QVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDS 107
LE +K++ +V C + ++ DF+V DG+V+ R + + ++ +FT+ W S
Sbjct: 43 LEADKIIGRVNLEECFRSADL-IRSSDPDFRVLNDGSVYTARAVALSDKKRSFTI--WLS 99
Query: 108 QTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRR 167
++ V +L+ H+ + K +H LRR
Sbjct: 100 DKRKQTQKEVTVLLE--------HQKKVSKT------------------RHTRETVLRRA 133
Query: 168 KRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSG 227
KR W P ++ ENS GPFP L ++ SD + + YSI+G G D+ P+ +F I+ +G
Sbjct: 134 KRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTG 193
Query: 228 RMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVD 287
++ TRP+DREE+ + L A+A +G + P+ L I V D NDN P F +YN V
Sbjct: 194 NLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVL 253
Query: 288 EGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGL 347
E S+PGT V V A D D+ T + ++Y I+ QTP+SP +F+++ TG I TV+ L
Sbjct: 254 ESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSP--GLFSVHPSTGVITTVSHYL 311
Query: 348 DREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVE 407
DRE V +Y++I++ DM+G +GL T+T IITVTD NDN P F + + V EN
Sbjct: 312 DREVVDKYSLIMKVQDMDGQF-FGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFN 370
Query: 408 TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRA 467
+ + + D+D ++ NW + I+ G+ +GHF + TD TNEG+++VVK ++YE NR
Sbjct: 371 VEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQ 430
Query: 468 FMLTVMVSNQAPLASGI-QMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVL 526
L + V+N+AP A I +++ + A VT+ + D++E P + +R++E + G+ +
Sbjct: 431 VNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKI 490
Query: 527 TTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFL 586
+ A DP+ +RY KL DP W+ I+ +G I T+ +LDRE KN +Y T L
Sbjct: 491 NGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVL 550
Query: 587 AADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGP 646
A D S TGTL + + D+NDN PE+L + IC KP + +I A D D + P
Sbjct: 551 AIDK--DDRSCTGTLAVNIEDVNDNPPEILQEYVVIC-KPKMGYTDILAVDPDEPVHGAP 607
Query: 647 YVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGM--YDVPIIVTDSGNPPLSNTS 704
+ F LP + + W++T++N A+LS + AG Y +PI V D + T
Sbjct: 608 FYFSLPNTSPEISRLWSLTKVNDTAARLSYQ---KNAGFQEYTIPITVKDRAGQ--AATK 662
Query: 705 IIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERH 764
+++V +C C C LG AI+AIL+ I +L +++L V + K +
Sbjct: 663 LLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKR 722
Query: 765 TKQLLIDPEDDVRDNILKYDEEGGGEE---DQDYDLSQLQQPEAMGHVPSKAPGVRRVDE 821
PED + N++ + E G++ + ++Q + G + G++ +
Sbjct: 723 F------PEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQ 776
Query: 822 RPV--------------GAEPQYPIRPMVPHPGDIGDF--------------INEGL-RA 852
+ GA + + ++ + + E L R
Sbjct: 777 ETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEKLHRC 836
Query: 853 ADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLAD 908
N+ P D +L ++YEG GS AGSV + D D+LN+ P+F LA+
Sbjct: 837 NQNEDRMPSQDYVLTYNYEGRGSPAGSVGCCSEKQEED-GLDFLNNLEPKFITLAE 891
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 401 bits (1030), Expect = e-111
Identities = 274/769 (35%), Positives = 408/769 (53%), Gaps = 47/769 (6%)
Query: 165 RRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSID 223
+R KR WV V E G P + ++ SD D D I+Y ++G GA VF+ID
Sbjct: 55 QRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI----VFTID 110
Query: 224 SMSGRMYVTRPMDREEHASYHLRAHAVDMN-GNKVENPIDLYIYVIDMNDNRPEFINQVY 282
+G ++ + +DREE A Y LRA A+D G +E + I + D+NDN P+F++ Y
Sbjct: 111 DTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPY 170
Query: 283 NGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVT 342
+V E S GT V+ VTA DADD T N R+V Q Q F+++S+TG I T
Sbjct: 171 VATVPEMSPVGTSVIQVTATDADDPTYGNSA---RVVYSILQ--GQPYFSVDSKTGVIRT 225
Query: 343 VAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVP 402
+DRE + Y VI+QA DM G L GL+ T T IT++DVNDNPP F + V
Sbjct: 226 ALMNMDREAKEYYEVIIQAKDMGGQLG-GLAGTTTVNITLSDVNDNPPRFPQKHYQMSVL 284
Query: 403 ENR-VETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVD 461
E+ + + V + D D+ N Y I+ GD + F + TDP G++TV K +
Sbjct: 285 ESAPISSTVGRVFAKDLDE--GINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLS 342
Query: 462 YELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRLEEGV 520
+E +++ L V +N + + FQ T V IS+ D++E P F + + E V
Sbjct: 343 FESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDV 402
Query: 521 PPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPASWLHINATNGQITTAAVLDRESLYTKN 578
GT + SA DPD ++RYS + SDP + +++ T G + TA LDRE N
Sbjct: 403 AIGTTIQIISAKDPD-VTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHN 461
Query: 579 NVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPK--EAQICEKPNLNAI--NIT 634
T LA + P G+ + I ++D+NDNAPE P+ EA +CE + ++
Sbjct: 462 ----ITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPE-FPRFYEAFVCENAKAGQLIQTVS 516
Query: 635 AADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLR---ILYLEAGMYDVPII 691
A D D DP G + + AA N+TI + A++ R E ++ +PI+
Sbjct: 517 AVDQD-DPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPIL 575
Query: 692 VTDSGNPPLSNTSIIKVKVCPCDDNG---DCTTIGAVAAAGLGTGAIVAILICILILLTM 748
+ DSG P LS+T + ++VC CDD+G C+ + L GA++AIL CI +LL +
Sbjct: 576 IADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVL 635
Query: 749 VLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQP-EAM 806
VLL ++ M+R K+ + +ID E+++ +NI++YD+EGGGEED + +D++ + P EA
Sbjct: 636 VLL-ILSMRRHRKQPY----IIDDEENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQ 690
Query: 807 GHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLL 866
K R D P + + ++ L AD D APP+DSL
Sbjct: 691 AGAAPKT----RQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEADMDLWAPPFDSLQ 746
Query: 867 VFDYEGSGSTAGSVSSLNSSSS-GDQDYDYLNDWGPRFKKLADMYGGGE 914
+ +EG GS AGS+SSL S++S +Q +D+L DWGPRF+KLA++YG E
Sbjct: 747 TYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASE 795
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 397 bits (1021), Expect = e-110
Identities = 283/770 (36%), Positives = 415/770 (53%), Gaps = 51/770 (6%)
Query: 166 RRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSIDS 224
R KR WV V E GP PQ + ++ S+ D D ++Y +TG GA +F ID
Sbjct: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGT----IFIIDD 105
Query: 225 MSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFINQVYN 283
+G ++ T+ +DRE+ Y L A A+D NK +E + I V D+NDN P+F + Y
Sbjct: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
Query: 284 GSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTV 343
+V E S GT V+ VTA DADD T N R+V Q Q F+++ +TG I T
Sbjct: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSA---RVVYSILQG--QPYFSVDPKTGVIRTA 220
Query: 344 AAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPE 403
+DRE + Y+V++QA DM G + GLS + T IT+TDVNDNPP F + VPE
Sbjct: 221 LHNMDREAREHYSVVIQAKDMAGQVG-GLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPE 279
Query: 404 N-RVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDY 462
+ +V + V + D D N + Y II+GD G FS+ TD T EG++++ K ++Y
Sbjct: 280 SAQVGSAVGKIKANDADT--GSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNY 337
Query: 463 ELNRAFMLTVMVSN-QAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVP 521
E +++ L + +N F+ + I + D++E P F L+ + E
Sbjct: 338 EKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAK 397
Query: 522 PGTVLTTFSAVDPDR---FMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKN 578
GTV+ T A DPD ++ + Y+ D + +I+A G I T VLDRE +
Sbjct: 398 IGTVVGTVLAQDPDSTNSLVRYFINYNVEDD--RFFNIDANTGTIRTTKVLDRE----ET 451
Query: 579 NVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPK-EAQICE--KPNLNAINITA 635
Y T A++ P T+ I ++D+NDN PEL + + +CE KP I+A
Sbjct: 452 PWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTISA 511
Query: 636 ADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDV---PIIV 692
D D N + F L V N+T+ + A + R + DV PI++
Sbjct: 512 TDKDDFANGPRFNFFLD-ERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMI 570
Query: 693 TDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVA---AAGLGTGAIVAILICILILLTMV 749
+D G P LS++S + ++VC C+ +G T A A +AGL TGA++AIL+C+LILL +V
Sbjct: 571 SDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLAIV 630
Query: 750 LLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPEAMGH 808
+LF+ RR K K+ LI E+DVR+N++ YD+EGGGEED + +D++ L+ P A
Sbjct: 631 VLFITL--RRSK----KEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAAEE 684
Query: 809 VPSKAPGVRRVDERP-VGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLV 867
+ R D RP V P++ + D+ +FI + L AD DP+ PPYDSL
Sbjct: 685 LKY------RRDIRPEVKLTPRHQTSSTLESI-DVQEFIKQRLAEADLDPSVPPYDSLQT 737
Query: 868 FDYEGSGSTAGSVSSLNSSSS-GDQDYDYLNDWGPRFKKLADMYGGGEED 916
+ YEG S AGS+SSL+S+++ DQDY YL DWGP FKKLA++YG E +
Sbjct: 738 YAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAELYGEIESE 787
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 396 bits (1018), Expect = e-110
Identities = 247/747 (33%), Positives = 394/747 (52%), Gaps = 50/747 (6%)
Query: 49 LEGEKLL-QVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDS 107
LE +K++ +V C + ++ DF+V DG+V+ R + + ++ +FT+ W S
Sbjct: 43 LEADKIIGRVNLEECFRSADL-IRSSDPDFRVLNDGSVYTARAVALSDKKRSFTI--WLS 99
Query: 108 QTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRR 167
++ V +L+ H+ + K +H LRR
Sbjct: 100 DKRKQTQKEVTVLLE--------HQKKVSKT------------------RHTRETVLRRA 133
Query: 168 KRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSG 227
KR W P ++ ENS GPFP L ++ SD + + YSI+G G D+ P+ +F I+ +G
Sbjct: 134 KRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTG 193
Query: 228 RMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVD 287
++ TRP+DREE+ + L A+A +G + P+ L I V D NDN P F +YN V
Sbjct: 194 NLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFTEAIYNFEVL 253
Query: 288 EGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGL 347
E S+PGT V V A D D+ T + ++Y I+ QTP+SP +F+++ TG I TV+ L
Sbjct: 254 ESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSP--GLFSVHPSTGVITTVSHYL 311
Query: 348 DREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVE 407
DRE V +Y++I++ DM+G +GL T+T IITVTD NDN P F + + V EN
Sbjct: 312 DREVVDKYSLIMKVQDMDGQF-FGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFN 370
Query: 408 TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRA 467
+ + + D+D ++ NW + I+ G+ +GHF + TD TNEG+++VVK ++YE NR
Sbjct: 371 VEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQ 430
Query: 468 FMLTVMVSNQAPLASGI-QMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVL 526
L + V+N+AP A I +++ + A VT+ + D++E P + +R++E + G+ +
Sbjct: 431 VNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKI 490
Query: 527 TTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFL 586
+ A DP+ +RY KL DP W+ I+ +G I T+ +LDRE KN +Y T L
Sbjct: 491 NGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVL 550
Query: 587 AADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGP 646
A D S TGTL + + D+NDN PE+L + IC KP + +I A D D + P
Sbjct: 551 AIDK--DDRSCTGTLAVNIEDVNDNPPEILQEYVVIC-KPKMGYTDILAVDPDEPVHGAP 607
Query: 647 YVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGM--YDVPIIVTDSGNPPLSNTS 704
+ F LP + + W++T++N A+LS + AG Y +PI V D + T
Sbjct: 608 FYFSLPNTSPEISRLWSLTKVNDTAARLSYQ---KNAGFQEYTIPITVKDRAGQ--AATK 662
Query: 705 IIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERH 764
+++V +C C C LG AI+AIL+ I +L +++L V + K +
Sbjct: 663 LLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKR 722
Query: 765 TKQLLIDPEDDVRDNILKYDEEGGGEE 791
PED + N++ + E G++
Sbjct: 723 F------PEDLAQQNLIISNTEAPGDD 743
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 388 bits (996), Expect = e-107
Identities = 257/752 (34%), Positives = 394/752 (52%), Gaps = 57/752 (7%)
Query: 49 LEGEKLL-QVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDS 107
L+ E L+ +V C+ + + ++ F++ DG+++ T +L + SE+ +F++ D
Sbjct: 41 LQAETLVGKVNLEECLKS-ASLIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDG 99
Query: 108 QTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRR 167
Q E+ + V L + SP H KDT L+R
Sbjct: 100 QRREQQEIKVVLSARENKSPKKRHT----------------KDT-----------ALKRS 132
Query: 168 KRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSG 227
KR W P ++ ENS GPFPQ + +I+SD + I YSI+G G D+ P +F I+ +G
Sbjct: 133 KRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYIEKDTG 192
Query: 228 RMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVD 287
++ TR +DRE++ + L +A +G E P+ L I + D NDN P F ++V +V
Sbjct: 193 DIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVP 252
Query: 288 EGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGL 347
E + GT V VTA D D+ T + ++Y+I+ Q P P F+I+ +TG I T L
Sbjct: 253 ENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKH--FSIHPDTGVITTTTPFL 310
Query: 348 DREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVE 407
DREK Y +I++ DM G +GL NT T I++ D NDNPP FT +++ EV ENR++
Sbjct: 311 DREKCDTYQLIMEVRDM-GGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENRID 369
Query: 408 TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRA 467
+ + V D+D P++P+ AVY+I+ G+ +G+F + TDP TNEG++ VVK ++YE+NR
Sbjct: 370 VEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQ 429
Query: 468 FMLTVMVSNQAPL--ASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTV 525
+L V V N+A A+ Q T VT+ I+D +E P K+I+ ++G P G
Sbjct: 430 VILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQE 489
Query: 526 LTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATF 585
L + A+DP+ + +RY KL D +W IN G + T VLDRES + KNN Y +
Sbjct: 490 LLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISV 549
Query: 586 LAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIG 645
+A D S TGTL ++L D ND+AP+ + KE IC+ N + + D D N
Sbjct: 550 VAVD--AVGRSCTGTLVVHLDDYNDHAPQ-IDKEVTICQN-NEDFAVLKPVDPDGPENGP 605
Query: 646 PYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSI 705
P+ F F+ + KNW I +G A L R L+ Y VPI + D L T +
Sbjct: 606 PFQF---FLDNSASKNWNIEEKDGKTAILRQR-QNLDYNYYSVPIQIKDRHG--LVATHM 659
Query: 706 IKVKVCPCDDNGDC-----TTIGAVAAAGLGTGAIVAILI-CILILLTMVLLFVMWMKRR 759
+ V+VC C +C +T LG AI+A+++ +L+L + F + KR
Sbjct: 660 LTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRT 719
Query: 760 EKERHTKQLLIDPEDDVRDNILKYDEEGGGEE 791
K+ PED + N++ + EG GEE
Sbjct: 720 VKK-------CFPEDIAQQNLIVSNTEGPGEE 744
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 388 bits (996), Expect = e-107
Identities = 257/752 (34%), Positives = 394/752 (52%), Gaps = 57/752 (7%)
Query: 49 LEGEKLL-QVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDS 107
L+ E L+ +V C+ + + ++ F++ DG+++ T +L + SE+ +F++ D
Sbjct: 41 LQAETLVGKVNLEECLKS-ASLIRSSDPAFRILEDGSIYTTHDLILSSERKSFSIFLSDG 99
Query: 108 QTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRR 167
Q E+ + V L + SP H KDT L+R
Sbjct: 100 QRREQQEIKVVLSARENKSPKKRHT----------------KDT-----------ALKRS 132
Query: 168 KRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSG 227
KR W P ++ ENS GPFPQ + +I+SD + I YSI+G G D+ P +F I+ +G
Sbjct: 133 KRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFNLFYIEKDTG 192
Query: 228 RMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVD 287
++ TR +DRE++ + L +A +G E P+ L I + D NDN P F ++V +V
Sbjct: 193 DIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVP 252
Query: 288 EGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGL 347
E + GT V VTA D D+ T + ++Y+I+ Q P P F+I+ +TG I T L
Sbjct: 253 ENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKH--FSIHPDTGVITTTTPFL 310
Query: 348 DREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVE 407
DREK Y +I++ DM G +GL NT T I++ D NDNPP FT +++ EV ENR++
Sbjct: 311 DREKCDTYQLIMEVRDM-GGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVEENRID 369
Query: 408 TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRA 467
+ + V D+D P++P+ AVY+I+ G+ +G+F + TDP TNEG++ VVK ++YE+NR
Sbjct: 370 VEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLNYEVNRQ 429
Query: 468 FMLTVMVSNQAPL--ASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTV 525
+L V V N+A A+ Q T VT+ I+D +E P K+I+ ++G P G
Sbjct: 430 VILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQE 489
Query: 526 LTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATF 585
L + A+DP+ + +RY KL D +W IN G + T VLDRES + KNN Y +
Sbjct: 490 LLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISV 549
Query: 586 LAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIG 645
+A D S TGTL ++L D ND+AP+ + KE IC+ N + + D D N
Sbjct: 550 VAVD--AVGRSCTGTLVVHLDDYNDHAPQ-IDKEVTICQN-NEDFAVLKPVDPDGPENGP 605
Query: 646 PYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSI 705
P+ F F+ + KNW I +G A L R L+ Y VPI + D L T +
Sbjct: 606 PFQF---FLDNSASKNWNIEEKDGKTAILRQR-QNLDYNYYSVPIQIKDRHG--LVATHM 659
Query: 706 IKVKVCPCDDNGDC-----TTIGAVAAAGLGTGAIVAILI-CILILLTMVLLFVMWMKRR 759
+ V+VC C +C +T LG AI+A+++ +L+L + F + KR
Sbjct: 660 LTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAILAMVLGSVLLLCILFTCFCVTAKRT 719
Query: 760 EKERHTKQLLIDPEDDVRDNILKYDEEGGGEE 791
K+ PED + N++ + EG GEE
Sbjct: 720 VKK-------CFPEDIAQQNLIVSNTEGPGEE 744
Score = 31.2 bits (69), Expect = 4.6
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 863 DSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLA 907
D + ++YEG GS AGSV S ++ ++L+ P+F+ LA
Sbjct: 845 DYVCSYNYEGKGSLAGSVGCC-SDRQEEEGLEFLDHLEPKFRTLA 888
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 387 bits (994), Expect = e-107
Identities = 280/902 (31%), Positives = 439/902 (48%), Gaps = 90/902 (9%)
Query: 49 LEGEKLL-QVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDS 107
L+ EKL+ +V C T ++ DF++ DG+V+ T + + SE+ +FT+ ++
Sbjct: 43 LDAEKLVGRVNLKECF-TAANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNT 101
Query: 108 QTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRR 167
+ EK V L H+ + KK +H LRR
Sbjct: 102 ENQEKKKIFVFL----------EHQTKVLKK------------------RHTKEKVLRRA 133
Query: 168 KRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSG 227
KR W P ++ ENS GPFP L +++SD + I YSI G G DQ P +F ++ +G
Sbjct: 134 KRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVERDTG 193
Query: 228 RMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVD 287
+Y TRP+DRE++ S+ + A A +G E P+ L I + D NDN P F + Y ++
Sbjct: 194 NLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTFTIF 253
Query: 288 EGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGL 347
E + GT V V A D D+ T + ++Y I+ Q P SP+ +F+++ TG I T ++ L
Sbjct: 254 ENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPT--LFSMHPTTGVITTTSSQL 311
Query: 348 DREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVE 407
DRE + +Y + ++ DM+G +GL T+T II + DVND+ P FT +++ V EN V+
Sbjct: 312 DRELIDKYQLKIKVQDMDGQY-FGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTVD 370
Query: 408 TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRA 467
+ +TV D+D ++ NW A Y I+ G+ +G+F + TD TNEG++ VVK ++YE +
Sbjct: 371 VEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQ 430
Query: 468 FMLTVMVSNQAPLA-SGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVL 526
+L + V N+AP + S STA VT+++ D +E P + +R++E GT
Sbjct: 431 MILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTS 490
Query: 527 TTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFL 586
+ A DP+ +RY KL+DP W+ I+ G I LDRE+ KN +Y T L
Sbjct: 491 NGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIYNITVL 550
Query: 587 AADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGP 646
A+D G + TGTL I L D+NDN+P +PK+ I KP +++ I A D D + P
Sbjct: 551 ASDQG--GRTCTGTLGIILQDVNDNSP-FIPKKTVIICKPTMSSAEIVAVDPDEPIHGPP 607
Query: 647 YVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSII 706
+ F L + V++ W + +N A+LS + G Y VPI V D +S+ + +
Sbjct: 608 FDFSLESSTSEVQRMWRLKAINDTAARLSYQ-NDPPFGSYVVPITVRD--RLGMSSVTSL 664
Query: 707 KVKVCPCDDNGDCT-----TIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREK 761
V +C C DCT IG LG AI+AIL+ I +L ++ V
Sbjct: 665 DVTLCDCITENDCTHRVDPRIGG-GGVQLGKWAILAILLGIALLFCILFTLVCGASGT-- 721
Query: 762 ERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYD----LSQLQQPEAMGHVPSKAPGVR 817
+KQ + P+D + N++ + E G +D+ Y +Q A G + G++
Sbjct: 722 ---SKQPKVIPDDLAQQNLIVSNTEAPG-DDKVYSANGFTTQTVGASAQGVCGTVGSGIK 777
Query: 818 RVDERPV-----GAEPQYPIRPMVPHPGDIGDFINEGLRAADN---------DPTAP--- 860
+ + G + R H D G DN T P
Sbjct: 778 NGGQETIEMVKGGHQTSESCRGAGHH--HTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLG 835
Query: 861 --------------PYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKL 906
D +L ++YEG GS AGSV + D ++L++ P+F+ L
Sbjct: 836 EKVYLCNQDENHKHAQDYVLTYNYEGRGSVAGSVGCCSERQEED-GLEFLDNLEPKFRTL 894
Query: 907 AD 908
A+
Sbjct: 895 AE 896
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 381 bits (979), Expect = e-105
Identities = 248/750 (33%), Positives = 389/750 (51%), Gaps = 51/750 (6%)
Query: 49 LEGEKLL-QVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDS 107
L+ EKL+ +V C T ++ DF++ DG+V+ T + + SE+ +FT+ ++
Sbjct: 43 LDAEKLVGRVNLKECF-TAANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNT 101
Query: 108 QTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRR 167
+ EK V L H+ + KK +H LRR
Sbjct: 102 ENQEKKKIFVFL----------EHQTKVLKK------------------RHTKEKVLRRA 133
Query: 168 KRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSG 227
KR W P ++ ENS GPFP L +++SD + I YSI G G DQ P +F ++ +G
Sbjct: 134 KRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVERDTG 193
Query: 228 RMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVD 287
+Y TRP+DRE++ S+ + A A +G E P+ L I + D NDN P F + Y ++
Sbjct: 194 NLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTFTIF 253
Query: 288 EGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGL 347
E + GT V V A D D+ T + ++Y I+ Q P SP+ +F+++ TG I T ++ L
Sbjct: 254 ENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPT--LFSMHPTTGVITTTSSQL 311
Query: 348 DREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVE 407
DRE + +Y + ++ DM+G +GL T+T II + DVND+ P FT +++ V EN V+
Sbjct: 312 DRELIDKYQLKIKVQDMDGQY-FGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTVD 370
Query: 408 TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRA 467
+ +TV D+D ++ NW A Y I+ G+ +G+F + TD TNEG++ VVK ++YE +
Sbjct: 371 VEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQ 430
Query: 468 FMLTVMVSNQAPLA-SGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVL 526
+L + V N+AP + S STA VT+++ D +E P + +R++E GT
Sbjct: 431 MILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTS 490
Query: 527 TTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFL 586
+ A DP+ +RY KL+DP W+ I+ G I LDRE+ KN +Y T L
Sbjct: 491 NGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIYNITVL 550
Query: 587 AADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGP 646
A+D G + TGTL I L D+NDN+P +PK+ I KP +++ I A D D + P
Sbjct: 551 ASDQG--GRTCTGTLGIILQDVNDNSP-FIPKKTVIICKPTMSSAEIVAVDPDEPIHGPP 607
Query: 647 YVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSII 706
+ F L + V++ W + +N A+LS + G Y VPI V D +S+ + +
Sbjct: 608 FDFSLESSTSEVQRMWRLKAINDTAARLSYQ-NDPPFGSYVVPITVRD--RLGMSSVTSL 664
Query: 707 KVKVCPCDDNGDCT-----TIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREK 761
V +C C DCT IG LG AI+AIL+ I +L ++ V
Sbjct: 665 DVTLCDCITENDCTHRVDPRIGG-GGVQLGKWAILAILLGIALLFCILFTLVCGASGT-- 721
Query: 762 ERHTKQLLIDPEDDVRDNILKYDEEGGGEE 791
+KQ + P+D + N++ + E G++
Sbjct: 722 ---SKQPKVIPDDLAQQNLIVSNTEAPGDD 748
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 376 bits (966), Expect = e-104
Identities = 280/770 (36%), Positives = 399/770 (51%), Gaps = 50/770 (6%)
Query: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSI 222
L R +R WV V E GP P + ++ SD D + +Y +TG GA VF I
Sbjct: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VFVI 94
Query: 223 DSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFINQV 281
D +G ++VT+ +DREE A Y L A AVD N+ +E P + I V D+NDN P F
Sbjct: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
Query: 282 YNGSVDEGSKPGTYVMTVTANDADDSTTANGM-VRYRIVTQTPQSPSQNMFTINSETGDI 340
Y+ +V E S GT V+ VTA+DADD + N + Y ++ P F+++ +TG +
Sbjct: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTGVV 208
Query: 341 VTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGE 400
T +DRE +++ V++QA DM G++ GLS + T +T++DVNDNPP+F S +
Sbjct: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMG-GLSGSTTVTVTLSDVNDNPPKFPQSLYQFS 267
Query: 401 VPENRVE-TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKA 459
V E T+V L D D N Y I+ G+ S FS+ TD +G++TV K
Sbjct: 268 VVETAGPGTLVGRLRAQDPDL--GDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKP 325
Query: 460 VDYELNRAFMLTVMVSNQAPLASGIQMS-FQSTAGVTISIMDINEAPYFPSNHKLIRLEE 518
+D+E R++ V +N + ++ F+ A V +++ D E P F + + E
Sbjct: 326 LDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPE 385
Query: 519 GVPPGTVLTTFSAVDPDRFMQQAVRYSKL--SDPASWLHINATNGQITTAAVLDRESLYT 576
PGT++ SA D D +RYS L SDP I G I TAA LDRE+
Sbjct: 386 NKAPGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAW 444
Query: 577 KNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELL-PKEAQICEK--PNLNAINI 633
N T LA + + + I +D NDNAP+L P + +C+ P I
Sbjct: 445 HN----LTVLATELDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVI 500
Query: 634 TAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSL--RILYLEAGMYDVPII 691
A D D N F+ P P A N+T+ A L L R Y VPI
Sbjct: 501 RALDRDEVGNSSHVSFQGPLGPDA---NFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIE 557
Query: 692 VTDSGNPPLSNTSIIKVKVCPCDDNGD---CTTIGAVAAAGLGTGAIVAILICILILLTM 748
+ D G P LS+T+ + V VC C +G C ++AAGL TGA++AI+ C+ LL +
Sbjct: 558 LWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLAL 617
Query: 749 VLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPEAMG 807
V+LFV RR+K+ + L++ E+DVR+NI+ YD+EGGGEED + +D++ LQ P+
Sbjct: 618 VVLFVAL--RRQKQ---EALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAA 672
Query: 808 HVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLV 867
P+ P RR D P + P RP P P D+ + LR AD DP PPYDS+ V
Sbjct: 673 P-PAPGPPARR-DVLPRARVSRQP-RP--PGPADVAQLLALRLREADEDPGVPPYDSVQV 727
Query: 868 FDYEGSGSTAGSVSSLNSSS---SGDQDYDYLNDWGPRFKKLADMYGGGE 914
+ YEG GS+ GS+SSL S S + L+DWGP F+ LA++YG E
Sbjct: 728 YGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKE 777
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 372 bits (955), Expect = e-103
Identities = 276/816 (33%), Positives = 411/816 (50%), Gaps = 62/816 (7%)
Query: 136 GKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRS 195
G+ A PSP P + A G R KR WV V E G P + +I S
Sbjct: 34 GRLWAAGTPSPSA-----PGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHS 88
Query: 196 DKDN-DIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNG 254
D D D I+Y+I+G GA +F ID ++G ++ +DRE+ Y LRA A D
Sbjct: 89 DSDEGDGAIKYTISGEGAGT----IFLIDELTGDIHAMERLDREQKTFYTLRAQARDRAT 144
Query: 255 NKVENP-IDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGM 313
N++ P + I V D+ND+ P F++ Y GSV E S GT VM V A+DADD T +
Sbjct: 145 NRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSA 204
Query: 314 VRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLS 373
R+V ++ FT++ +TG I T LDRE ++Y V++QATDM G L GLS
Sbjct: 205 ---RLVYSVLDG--EHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLG-GLS 258
Query: 374 NTATAIITVTDVNDNPPEFTASTFAGEVPENR-VETVVANLTVMDRDQPHSPNWNAVYRI 432
+ T I VTDVNDNPP F + + E+ + T V + D D N + Y +
Sbjct: 259 GSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDV--GENTDMTYHL 316
Query: 433 ISGDPSGH--FSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQM-SFQ 489
SG F V TD T E ++ V K +D+E + + N+ + +F+
Sbjct: 317 KDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFR 376
Query: 490 STAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYS--KL 547
A V +++ D++E P F L+ ++E G+++ +A DPD + VRY+ +
Sbjct: 377 DQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDA-ANRPVRYAIDRE 435
Query: 548 SDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLID 607
SD I+A G I T LDRE+ N T LA + +L+I ++D
Sbjct: 436 SDLDQIFDIDADTGAIVTGKGLDRETAGWHN----ITVLAMEADNHAQLSRASLRIRILD 491
Query: 608 INDNAPELL-PKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRK-NWTIT 665
+NDN PEL P EA +CE + T + D D G + F VP A ++++
Sbjct: 492 VNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLL 551
Query: 666 RLNGDYAQLSLRILYL---EAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNG---DC 719
+ + A + + + E ++ +PI+V DSG P LS+T + +++C CD +G C
Sbjct: 552 DIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSC 611
Query: 720 TTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDN 779
T V AA L GA++A+L+C+LIL+ +VLL ++ ++R H L D ++D+RDN
Sbjct: 612 NTTAFVMAASLSPGALIALLVCVLILVVLVLL-ILTLRRH----HKSHLSSDEDEDMRDN 666
Query: 780 ILKYDEEGGGEEDQD-YDLSQLQQPEAMGHVP------SKAPGVRRVDERPVGAEPQ--- 829
++KY++EGGGE+D + YD+S L+ G + S G G+ PQ
Sbjct: 667 VIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAGGGSGGGAGSPPQAHL 726
Query: 830 ------YPIRPMVPHP--GDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVS 881
P P P P DFI+ + AD D + PPYD+ + +EG+ S A S+S
Sbjct: 727 PSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAFQTYAFEGADSPAASLS 786
Query: 882 SLNSSSSG-DQDYDYLNDWGPRFKKLADMYGGGEED 916
SL+S SSG +QD+ YL+ WGPRF+ LA +Y G D
Sbjct: 787 SLHSGSSGSEQDFAYLSSWGPRFRPLAALYAGHRGD 822
>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
Length = 819
Score = 367 bits (942), Expect = e-101
Identities = 288/807 (35%), Positives = 401/807 (49%), Gaps = 86/807 (10%)
Query: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSI 222
L R +R WV V E GP P + ++ SD D + +Y +TG GA VF I
Sbjct: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VFVI 94
Query: 223 DSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFINQV 281
D +G ++VT+ +DREE A Y L A AVD N+ +E P + I V D+NDN P F
Sbjct: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
Query: 282 YNGSVDEGSKPGTYVMTVTANDADDSTTAN-GMVRYRIVTQTPQSPSQNMFTINSETGDI 340
Y+ +V E S GT V+ VTA+DADD + N + Y ++ P F+++ +TG +
Sbjct: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTGVV 208
Query: 341 VTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGE 400
T +DRE +++ V++QA DM G++ GLS + T +T++DVNDNPP+F S +
Sbjct: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMG-GLSGSTTVTVTLSDVNDNPPKFPQSLYQFS 267
Query: 401 VPENR-VETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKA 459
V E T+V L D D N Y I+ G+ S FS+ TD +G++TV K
Sbjct: 268 VVETAGPGTLVGRLRAQDPDL--GDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKP 325
Query: 460 VDYELNRAFMLTVMVSN----QAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIR 515
+D+E R++ V +N A L G F+ A V +++ D E P F +
Sbjct: 326 LDFESQRSYSFRVEATNTLIDPAYLRRG---PFKDVASVRVAVQDAPEPPAFTQAAYHLT 382
Query: 516 LEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKL--SDPASWLHINATNGQITTAAVLDRES 573
+ E PGT++ SA D D +RYS L SDP I G I TAA LDRE+
Sbjct: 383 VPENKAPGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREA 441
Query: 574 LYTKNNVYEATFL----------------------AADNGIPPASGTGTLQ--------- 602
N AT L A P S G Q
Sbjct: 442 RAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRV 501
Query: 603 ---IYLIDINDNAPELL-PKEAQICEK--PNLNAINITAADADVDPNIGPYVFELPFVPA 656
I +D NDNAP+L P + +C+ P I A D D N F+ P P
Sbjct: 502 QVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPD 561
Query: 657 AVRKNWTITRLNGDYAQLSL--RILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCD 714
A N+T+ A L L R Y VPI + D G P LS+T+ + V VC C
Sbjct: 562 A---NFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQ 618
Query: 715 DNG---DCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLID 771
+G C ++AAGL TGA++AI+ C+ LL +V+LFV RR+K+ + L++
Sbjct: 619 PDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFV--ALRRQKQ---EALMVL 673
Query: 772 PEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQY 830
E+DVR+NI+ YD+EGGGEED + +D++ LQ P+ P+ P RR D P +
Sbjct: 674 EEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAA-PPAPGPPARR-DVLPRARVSRQ 731
Query: 831 PIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSS--- 887
P RP P P D+ + LR AD DP PPYDS+ V+ YEG GS+ GS+SSL S S
Sbjct: 732 P-RP--PGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAG 788
Query: 888 SGDQDYDYLNDWGPRFKKLADMYGGGE 914
+ L+DWGP F+ LA++YG E
Sbjct: 789 GAPGPAEPLDDWGPLFRTLAELYGAKE 815
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 350 bits (897), Expect = 4e-96
Identities = 264/796 (33%), Positives = 411/796 (51%), Gaps = 66/796 (8%)
Query: 139 VVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKD 198
V A +P +DT P H RR+KRDW+ +++ E P + +I+S
Sbjct: 23 VAAAGANPAQRDTHSLLPTH------RRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVS 76
Query: 199 NDIPIRYSITG--VGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMN-GN 255
+Y + G VG +VF +D+ +G ++ +DRE + YHL A VD + G
Sbjct: 77 RK-NAKYLLKGEYVG------KVFRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTGE 129
Query: 256 KVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTA-NGMV 314
+E P I V D+NDN P F ++++N SV E S GT V++VTA DADD T + V
Sbjct: 130 NLETPSSFTIKVHDVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASV 189
Query: 315 RYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSN 374
Y+I+ + F I++ +G I+T+ LDREK +Y ++V+A D +G G S
Sbjct: 190 MYQIL------KGKEYFAIDN-SGRIITITKSLDREKQARYEIVVEARDAQG--LRGDSG 240
Query: 375 TATAIITVTDVNDNPPEFTASTFAGEVPEN-RVETVVANLTVMDRDQPHSPNWNAVYRII 433
TAT ++T+ D+NDN P FT + + VPE+ RV T V +L V D D+P N Y I+
Sbjct: 241 TATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSVGSLFVEDPDEPQ--NRMTKYSIL 298
Query: 434 SGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAG 493
GD F++ T+P NEG++ +K +DYE + + V ++ + + A
Sbjct: 299 RGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQ 358
Query: 494 VTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYS--KLSDPA 551
V I+I D++E P F +L+E ++ T A+DPD + ++ YS + SD
Sbjct: 359 VIINITDVDEPPIFQQPFYHFQLKEN-QKKPLIGTVLAMDPDA-ARHSIGYSIRRTSDKG 416
Query: 552 SWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYL--IDIN 609
+ + G I LDRE N EA L D+ P +Q+++ +D N
Sbjct: 417 QFFRV-TKKGDIYNEKELDREVYPWYNLTVEAKEL--DSTGTPTGKESIVQVHIEVLDEN 473
Query: 610 DNAPELL-PKEAQICEKP--NLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITR 666
DNAPE P + ++CE + I+A D D+ P + F L N+T+T
Sbjct: 474 DNAPEFAKPYQPKVCENAVHGQLVLQISAIDKDITPRNVKFKFIL-----NTENNFTLTD 528
Query: 667 LNGDYAQLSLRILYLE---AGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIG 723
+ + A ++++ + ++ +P++++D+G P + TS + V VC C++ G+ T
Sbjct: 529 NHDNTANITVKYGQFDREHTKVHFLPVVISDNGMPSRTGTSTLTVAVCKCNEQGEFTFCE 588
Query: 724 AVAA-AGLGTGAIVAILICILILLTMVLLFVMWMKRREKER-HTKQLLIDPEDDVRDNIL 781
+AA G+ A+VAIL+CIL + + LL + + R++ R H K + ++ + ++
Sbjct: 589 DMAAQVGVSIQAVVAILLCILTITVITLLIFLRRRLRKQARAHGKSV-----PEIHEQLV 643
Query: 782 KYDEEGGGEED-QDYDLSQLQQPEAMGHVPSKAPGVRRVDERP-VGAEPQYPIRPMV--- 836
YDEEGGGE D YD+S L G P + +D RP + A+ Q P R
Sbjct: 644 TYDEEGGGEMDTTSYDVSVLNSVRRGGAKPPRP----ALDARPSLYAQVQKPPRHAPGAH 699
Query: 837 PHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNS-SSSGDQDYDY 895
PG++ I AD+D PPYD+L ++ YEGS S A S+SSL + SS D DYD+
Sbjct: 700 GGPGEMAAMIEVKKDEADHDGDGPPYDTLHIYGYEGSESIAESLSSLGTDSSDSDVDYDF 759
Query: 896 LNDWGPRFKKLADMYG 911
LNDWGPRFK LA++YG
Sbjct: 760 LNDWGPRFKMLAELYG 775
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 346 bits (887), Expect = 6e-95
Identities = 241/824 (29%), Positives = 395/824 (47%), Gaps = 72/824 (8%)
Query: 138 KVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDK 197
+V +D D L + + LRR KR WVI + + E GPFP+ + + ++
Sbjct: 23 QVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNM 82
Query: 198 DNDIPIRYSITGVGADQ-PPMEVFSI-DSMSGRMYVTRPMDREEHASYHLRAHAVDMNGN 255
++ + Y I+G G D+ P + +FS+ D +GR+YV RP+DRE S+ + V+ +
Sbjct: 83 SYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTG 142
Query: 256 K-VENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMV 314
K V+ + I + D+ND+ P+F + +N +V E G + + A D D+ T N V
Sbjct: 143 KIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQV 202
Query: 315 RYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSN 374
Y +++QTP ++ F ++ +G+I ++ LD E Q+T++++A D LS+
Sbjct: 203 LYFLISQTPLL-KESGFRVDRLSGEI-RLSGCLDYETAPQFTLLIRARDCG---EPSLSS 257
Query: 375 TATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIIS 434
T T + V + N++ P FT + ++PE R V L V DRD P + W A + I+
Sbjct: 258 TTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILH 317
Query: 435 GDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQ----- 489
G+ GHF + TDP TNEG++ V+K +DYE A L ++V N+ L + Q
Sbjct: 318 GNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKA 377
Query: 490 -STAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLS 548
++A V++ + D N+ P F ++ EEG PGT+L TF+A+DPD +RY +
Sbjct: 378 AASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPD----SQIRYELVH 433
Query: 549 DPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDI 608
DPA+W+ ++ +G + T +DRES + N+ Y A D+G PP + TGTL ++L DI
Sbjct: 434 DPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDI 493
Query: 609 NDNAPELLPKE--AQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITR 666
NDN P L P+ ++CE ++I A D D++P P+ FEL W + R
Sbjct: 494 NDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGR 553
Query: 667 LNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVA 726
G +L L + L G Y VP+ + D LS + V++CPC C + A A
Sbjct: 554 NWGQSVEL-LTLRSLPRGNYLVPLFIGDKQG--LSQKQTVHVRICPCASGLTCVEL-ADA 609
Query: 727 AAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEE 786
GL GA+ + + L +L + E +RH + D+ ++ Y+ E
Sbjct: 610 EVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSV---SNDEGHQTLVMYNAE 666
Query: 787 GGGEEDQDYDLSQLQQPEAMGHVPSKAP--GVRRVDERP--------------------- 823
G Q + + Q+P + + P GV+ ++E P
Sbjct: 667 SKGTSAQTWSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGK 726
Query: 824 ---------VGAEPQYPIRPM-----VPHPGDIGDFINEGLRAA---DNDPTAPPYDSLL 866
+ + P YP M P G + + +N+ L A ++DP P+
Sbjct: 727 PFEPRSVKNIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPH---- 782
Query: 867 VFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMY 910
V+ EG A S+SSL +S + D L+ G + ++Y
Sbjct: 783 VYSEEGECGGAPSLSSL-ASLEQELQPDLLDSLGSKATPFEEIY 825
>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
Length = 1118
Score = 327 bits (839), Expect = 2e-89
Identities = 196/605 (32%), Positives = 306/605 (50%), Gaps = 15/605 (2%)
Query: 156 PQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSD--KDNDIPIRYSITGVGAD 213
P+H + L R+KR W+ P+ + E + +I SD ++ + I Y TG G
Sbjct: 39 PKHPH---LVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGIT 95
Query: 214 QPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDN 273
+PP +F + +G + VT +DREE + L +A+D GN VE P++L I V+D+NDN
Sbjct: 96 EPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDN 155
Query: 274 RPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTI 333
P F V+ GSV+E S T VM + A DAD+ T N + YRIV+ P P +F +
Sbjct: 156 EPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPP--VFYL 213
Query: 334 NSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFT 393
N +TG+I T + LDRE+ YT+ V+A D G + A I + DVNDN P
Sbjct: 214 NKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVE 273
Query: 394 ASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGM 453
G V EN+V V + V D D+ S NW A + SG+ G+F + TD TNEG+
Sbjct: 274 NKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGI 333
Query: 454 VTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQST-AGVTISIMDINEAPYFPSNHK 512
VT++K VDYE + +V+V+N+A I+ ++ T + + + ++ E +F S+
Sbjct: 334 VTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVI 393
Query: 513 LIRLEEGV---PPGTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVL 569
I + E + G ++ F A D D + RY KL D +W+ +++ +I A +
Sbjct: 394 SIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLP 453
Query: 570 DRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLN 629
D ES Y +N Y +A P + TGT+ I + DINDN P L+ IC +
Sbjct: 454 DFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICH--DAE 511
Query: 630 AINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVP 689
+N+TA D D PN GP+ F + P + + W I R + + L+ + G ++
Sbjct: 512 YVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIAR--QESTSVLLQQSEKKLGRSEIQ 569
Query: 690 IIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMV 749
+++D+ ++ + VC C C + GLG AI +++ L+LL +
Sbjct: 570 FLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVP 629
Query: 750 LLFVM 754
LL +M
Sbjct: 630 LLLLM 634
>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
Length = 1040
Score = 323 bits (827), Expect = 6e-88
Identities = 239/815 (29%), Positives = 377/815 (46%), Gaps = 81/815 (9%)
Query: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSID 223
+RR+KR+W+ E + +IRSD +++ I Y I+GVG D+PP VF+I+
Sbjct: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTIN 103
Query: 224 SMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYN 283
+G + +T +DRE + + A++ G +E P++L + V+D+NDN P F VY
Sbjct: 104 PRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYT 163
Query: 284 GSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTV 343
S++E S T V+ + A DAD+ N + Y+IV+Q P MF +N TG++ T+
Sbjct: 164 ASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAP--MFILNRYTGEVCTM 221
Query: 344 AAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPE 403
++ LDRE+ Y ++V+ +D +G + GLS+ I V DVNDN P ++++ + E
Sbjct: 222 SSFLDREQHSMYNLVVRGSDRDGAAD-GLSSECDCRIKVLDVNDNFPTLEKTSYSASIEE 280
Query: 404 NRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYE 463
N + + + L +D D+ + NW A Y I+SG+ F ++TDP TNEG++ VVK +DYE
Sbjct: 281 NCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYE 340
Query: 464 LNRAFMLTVMVSNQAPLASGIQMSFQ-STAGVTISIMDINEAPYFPSNHKLIRLEEGVPP 522
L++ V NQA + FQ V I ++D+ E P F + + EG+
Sbjct: 341 QAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG 400
Query: 523 GT----VLTTFSAVDPDRFMQQA-VRYSKLSDPASWLHINATNGQITTAAVLDRESLYTK 577
+ VL T++A+D D VRY D SWL I++ G+I + D++S Y
Sbjct: 401 SSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYII 460
Query: 578 NNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAAD 637
N +Y A LA D+G + TGT+ I + DIND P + P+ IC I++
Sbjct: 461 NGIYTAEILAIDDG-SGKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHS 519
Query: 638 ADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGN 697
P+ F + P + W + N A L+ + + L G Y++PI+V DS N
Sbjct: 520 YG-----SPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQV-LSPGFYEIPILVKDSYN 573
Query: 698 PPLSNTSIIKVKVCPCDDNGDCTTIGA----------------------VAAAGLGTGAI 735
++++ C CDDN C GA V+ GLG I
Sbjct: 574 RACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGI 633
Query: 736 -VAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD 794
+ +L +L++L +LL + K+R+ E + PE + + EG ED+D
Sbjct: 634 GMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGG-EGVMQSWRIEGAHPEDRD 692
Query: 795 ----------------YDLSQL--QQPEAMGHVPSKAPGVR-------RVDERPVGAE-P 828
D S++ A G V GV V GA
Sbjct: 693 VSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGA 752
Query: 829 QYPIRPMVPHPGDIGDFINEGLRAA--------------DNDPTAPPYDSLLVFDYEGSG 874
R G + D+ + + A D D P D LL++D+EG G
Sbjct: 753 SGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVG 812
Query: 875 STAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADM 909
S GS+ S D D + P+F+ LA++
Sbjct: 813 SPVGSIGCC-SWIVDDLDESCMETLDPKFRTLAEI 846
>gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens]
Length = 772
Score = 318 bits (815), Expect = 1e-86
Identities = 252/763 (33%), Positives = 379/763 (49%), Gaps = 54/763 (7%)
Query: 166 RRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSIDS 224
R KR WV VPE + ++RSD DN + +Y + G GA F ID
Sbjct: 40 RVKRGWVWNQFFVPEEMNTT-SHHIGQLRSDLDNGNNSFQYKLLGAGAGS----TFIIDE 94
Query: 225 MSGRMYVTRPMDREEHASYHLRAHAVDM-NGNKVENPIDLYIYVIDMNDNRPEFINQVYN 283
+G +Y + +DREE + Y LRA +D+ G VE + I V D+NDN P+F+++ Y
Sbjct: 95 RTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPKFLDEPYE 154
Query: 284 GSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTV 343
V E S GT V+ VTA+DADD ++ N R++ Q Q F++ TG ++ +
Sbjct: 155 AIVPEMSPEGTLVIQVTASDADDPSSGNNA---RLLYSLLQ--GQPYFSVEPTTG-VIRI 208
Query: 344 AAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPE 403
++ +DRE +Y VI+QA DM G LS T + +I ++DVNDN P F S + V E
Sbjct: 209 SSKMDRELQDEYWVIIQAKDMIGQPG-ALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSE 267
Query: 404 NRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYE 463
+ T + T+M D N Y I D S F + T+ T EG+V + K VD+E
Sbjct: 268 S-APTGTSIGTIMAYDNDIGENAEMDYS-IEEDDSQTFDIITNHETQEGIVILKKKVDFE 325
Query: 464 LNRAFMLTVMVSN-QAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPP 522
+ + V N P + ST + I + D++E P F + + + E P
Sbjct: 326 HQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEETPQ 385
Query: 523 GTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYE 582
G+ + SA DPD + +RYS +IN NG ITT+ LDRE + Y
Sbjct: 386 GSFVGVVSATDPDN-RKSPIRYSITRSKV--FNIN-DNGTITTSNSLDREI----SAWYN 437
Query: 583 ATFLAADNGIPPASGTGTLQIYLIDINDNAPELLP-KEAQICEKPNLNAINITAADADVD 641
+ A + + L + +++IND+APE E +CE + T + D D
Sbjct: 438 LSITATEKYNIEQISSIPLYVQVLNINDHAPEFSQYYETYVCENAGSGQVIQTISAVDRD 497
Query: 642 PNIGPYVFELPF-VPAAVRKNWTITRLNGDYAQLSLR----ILYLEAGMYDVPIIVTDSG 696
+I + F V ++TI N D + L E ++ + I++ D+G
Sbjct: 498 ESIEEHHFYFNLSVEDTNNSSFTIID-NQDNTAVILTNRTGFNLQEEPVFYISILIADNG 556
Query: 697 NPPLSNTSIIKVKVCPCDDNGD---CTTIGAVAAAGLGTGAIVAILICILILLTMVLLFV 753
P L++T+ + + VC C D+G C V + G T I+AILICI+I+ + L
Sbjct: 557 IPSLTSTNTLTIHVCDCGDSGSTQTCQYQELVLSMGFKTEVIIAILICIMIIFGFIFL-T 615
Query: 754 MWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPEAMGHVPSK 812
+ +K+R K+ L + +D R+NI +YD+EGGGEED + +D+++L+ M
Sbjct: 616 LGLKQRRKQ----ILFPEKSEDFRENIFQYDDEGGGEEDTEAFDIAELRSSTIMR----- 666
Query: 813 APGVRRVDERPVGAEPQYPIRPMV---PHPGDIGDFINEGLRAADNDPTAPPYDSLLVFD 869
R + AE + R + P FI E L A+ DP APP+DSL +
Sbjct: 667 ----ERKTRKTTSAEIRSLYRQSLQVGPDSAIFRKFILEKLEEANTDPCAPPFDSLQTYA 722
Query: 870 YEGSGSTAGSVSSLNSS-SSGDQDYDYLNDWGPRFKKLADMYG 911
+EG+GS AGS+SSL S+ S D+ YDYLN+ GPRFK+LA M+G
Sbjct: 723 FEGTGSLAGSLSSLESAVSDQDESYDYLNELGPRFKRLACMFG 765
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,880,345
Number of Sequences: 37866
Number of extensions: 1788572
Number of successful extensions: 8896
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 4003
Number of HSP's gapped (non-prelim): 981
length of query: 916
length of database: 18,247,518
effective HSP length: 111
effective length of query: 805
effective length of database: 14,044,392
effective search space: 11305735560
effective search space used: 11305735560
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.