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Search of human proteins with 14589889
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
(906 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 1828 0.0
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 1243 0.0
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 736 0.0
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 638 0.0
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 592 e-169
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 520 e-147
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 447 e-125
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 439 e-123
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 439 e-123
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 429 e-120
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 429 e-120
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 429 e-120
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 429 e-120
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 426 e-119
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 423 e-118
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 419 e-117
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 418 e-116
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 413 e-115
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 413 e-115
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 412 e-115
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 397 e-110
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 393 e-109
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 376 e-104
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens] 364 e-100
gi|16753221 cadherin 22 precursor [Homo sapiens] 357 4e-98
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 357 4e-98
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 354 2e-97
gi|116534898 desmoglein 2 preproprotein [Homo sapiens] 336 5e-92
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] 317 4e-86
gi|197313787 desmoglein 4 isoform 1 [Homo sapiens] 309 9e-84
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 1828 bits (4735), Expect = 0.0
Identities = 906/906 (100%), Positives = 906/906 (100%)
Query: 1 MCRIAGALRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLNVKF 60
MCRIAGALRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLNVKF
Sbjct: 1 MCRIAGALRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLNVKF 60
Query: 61 SNCNGKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVK 120
SNCNGKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVK
Sbjct: 61 SNCNGKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVK 120
Query: 121 LSLKPTLTEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQEL 180
LSLKPTLTEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQEL
Sbjct: 121 LSLKPTLTEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQEL 180
Query: 181 VRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAV 240
VRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAV
Sbjct: 181 VRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAV 240
Query: 241 DINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNAL 300
DINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNAL
Sbjct: 241 DINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNAL 300
Query: 301 NGMLRYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTY 360
NGMLRYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTY
Sbjct: 301 NGMLRYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTY 360
Query: 361 GLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVY 420
GLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVY
Sbjct: 361 GLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVY 420
Query: 421 RISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQS 480
RISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQS
Sbjct: 421 RISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQS 480
Query: 481 TATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDP 540
TATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDP
Sbjct: 481 TATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDP 540
Query: 541 ANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDIND 600
ANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDIND
Sbjct: 541 ANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDIND 600
Query: 601 NAPQVLPQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGD 660
NAPQVLPQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGD
Sbjct: 601 NAPQVLPQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGD 660
Query: 661 FAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGL 720
FAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGL
Sbjct: 661 FAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGL 720
Query: 721 GTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGE 780
GTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGE
Sbjct: 721 GTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGE 780
Query: 781 EDQDYDLSQLQQPDTVEPDAIKPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGL 840
EDQDYDLSQLQQPDTVEPDAIKPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGL
Sbjct: 781 EDQDYDLSQLQQPDTVEPDAIKPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGL 840
Query: 841 KAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADM 900
KAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADM
Sbjct: 841 KAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADM 900
Query: 901 YGGGDD 906
YGGGDD
Sbjct: 901 YGGGDD 906
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 1243 bits (3215), Expect = 0.0
Identities = 604/914 (66%), Positives = 737/914 (80%), Gaps = 15/914 (1%)
Query: 5 AGALRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLNVKFSNCN 64
AG L LL L AL +A E CK GF ED Y+A++S+++ EG+ LL VKFS+C
Sbjct: 5 AGVLLLLLSLSGAL-RAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFSSCV 63
Query: 65 GKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLK 124
G + QYE++ DFKV DG V+A R + SE F + A D +T EKW V+L +
Sbjct: 64 GTKGTQYETNS-MDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVA 122
Query: 125 PTLTEESVKESAEVEEIV------------FPRQFSKHSGHLQRQKRDWVIPPINLPENS 172
T + S + + +++V P +++ L+R+KRDWVIPPIN+PENS
Sbjct: 123 QTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENS 182
Query: 173 RGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIAR 232
RGPFPQ+LVRIRSD+D ++ +RYS+TG GADQPP +F I+ +SG++ VT+P+DRE+ A
Sbjct: 183 RGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHAS 242
Query: 233 FHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAI 292
+HLRAHAVD+NGN+VENPID+ I VIDMNDNRPEF++QV+NG+V EGSKPGTYVMTVTA
Sbjct: 243 YHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTAN 302
Query: 293 DADDPNALNGMLRYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQAT 352
DADD NGM+RYRIV+Q P +PS NMFTIN+ETGDI+TVAAGLDREKVQQYT+I+QAT
Sbjct: 303 DADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQAT 362
Query: 353 DMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPH 412
DMEGN YGLSNTATA+ITVTDVNDNPPEFTA TF GEVPENRV+ +VANLTV D+DQPH
Sbjct: 363 DMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPH 422
Query: 413 TPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAK 472
+P WNAVYRI GDP+G F+++TDP +N+G+VTVVK +D+E NR F+LTV NQ PLA
Sbjct: 423 SPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLAS 482
Query: 473 GIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNI 532
GIQ QSTA V+++++D+NE PYF N K+IR EEG+ GT+LTTF+A DPDR+MQQ +
Sbjct: 483 GIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAV 542
Query: 533 RYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQ 592
RY+KLSDPA+WL I+ NGQITT AVLDRES KNN+Y ATFLA+DNGIPP SGTGTLQ
Sbjct: 543 RYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQ 602
Query: 593 IYLLDINDNAPQVLPQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNW 652
IYL+DINDNAP++LP+EA+ CE P+ N+INITA D D+DPN GP+ F+LP P +++NW
Sbjct: 603 IYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNW 662
Query: 653 TITRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDV 712
TITRLNGD+AQL+L+I +LEAG+Y+VPII+TDSGNPP SN SI++VKVC CD NGDCT +
Sbjct: 663 TITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTI 722
Query: 713 DRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILK 772
+ AGLGTGAI+AIL+CI+ILL +VL+FV+WMKRR+KER KQLLIDPEDDVRDNILK
Sbjct: 723 GAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILK 782
Query: 773 YDEEGGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRMDERPIHAEPQYPVRSAAPHPGDI 832
YDEEGGGEEDQDYDLSQLQQP+ + K G+RR+DERP+ AEPQYP+R PHPGDI
Sbjct: 783 YDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDI 842
Query: 833 GDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGP 892
GDFINEGL+AADNDPTAPPYDSLLVFDYEGSGSTAGS+SSLNSSSS G+QDYDYLNDWGP
Sbjct: 843 GDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSS-GDQDYDYLNDWGP 901
Query: 893 RFKKLADMYGGGDD 906
RFKKLADMYGGG++
Sbjct: 902 RFKKLADMYGGGEE 915
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 736 bits (1900), Expect = 0.0
Identities = 426/906 (47%), Positives = 555/906 (61%), Gaps = 43/906 (4%)
Query: 12 LPLLAALLQASVEASGEIALCKTGFPEDVYS-AVLSKDVHEGQPLLNVKFSNCNGKRKVQ 70
L L LLQ S E C GF + Y+ V + + G+ L V F +C G+++
Sbjct: 8 LSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTA 67
Query: 71 YESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSL-----KP 125
Y S + FKV DG++ R + FL+YA D T K+ V L+ +P
Sbjct: 68 YFSLDTR-FKVGTDGVITVKRPLRFHNPQIHFLVYAWDS-TYRKFSTKVTLNTVGHHHRP 125
Query: 126 TLTEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRS 185
+ SV + E + FP S L+RQKRDWVIPPI+ PEN +GPFP+ LV+I+S
Sbjct: 126 PPHQASVS-GIQAELLTFPNS----SPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKS 180
Query: 186 DRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGN 245
++DK + YS+TG GAD PP G+FII +G L VT+PLDRE+IA + L +HAV NGN
Sbjct: 181 NKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGN 240
Query: 246 QVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDP-NALNGML 304
VE+P++I+I V D NDN+PEF +V+ G+V EG+ PGT VM VTA DADD N N +
Sbjct: 241 AVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAI 300
Query: 305 RYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSN 364
Y I+SQ P P NMFTIN TG I V GLDRE YTL++QA D++G GLS
Sbjct: 301 AYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGE---GLST 357
Query: 365 TATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISG 424
TATAVITVTD NDNPP F T+ G+VPEN ++++ L VTD D P+TPAW AVY I
Sbjct: 358 TATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTIL- 416
Query: 425 GDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATV 484
D G+F + T+P +NDG++ K +DFE + ++L VA N VP + STATV
Sbjct: 417 NDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSL---TTSTATV 473
Query: 485 SVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWL 544
+V V+DVNE P F P K + E G +T++TAQ+PD +M+Q I Y D ANWL
Sbjct: 474 TVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWL 533
Query: 545 KIDPVNGQITTIAVLDRES-PNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAP 603
+I+P G I+T A LDRE +VKN+ Y A +A+DNG P +GTGTL + L D+NDNAP
Sbjct: 534 EINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP 593
Query: 604 QVLPQEAETCE-TPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFA 662
P+ CE P P INI +D D+ PN PF +L NWTI +
Sbjct: 594 IPEPRTIFFCERNPKPQVINI--IDADLPPNTSPFTAELTHG---ASANWTIQYNDPTQE 648
Query: 663 QLNLKIKF-LEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLG 721
+ LK K LE G Y++ + + D+ N K ++ L V VC C+ + V AGL
Sbjct: 649 SIILKPKMALEVGDYKINLKLMDNQN--KDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQ 706
Query: 722 TGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEE 781
AI+ IL I+ LLIL+L+ +++++RR K+ L+ PEDD RDN+ YDEEGGGEE
Sbjct: 707 IPAILGILGGILALLILILLLLLFLRRR---AVVKEPLLPPEDDTRDNVYYYDEEGGGEE 763
Query: 782 DQDYDLSQLQQPDTVEPDAIKPVGIRRMDERP-IHAEPQYPVRSAAPHPGDIGDFINEGL 840
DQD+DLSQL + P+ + R D P + + P+Y R A +P +IG+FI+E L
Sbjct: 764 DQDFDLSQLHRGLDARPE------VTRNDVAPTLMSVPRYLPRPA--NPDEIGNFIDENL 815
Query: 841 KAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADM 900
KAAD DPTAPPYDSLLVFDYEGSGS A SLSSLNSS S +QDYDYLN+WG RFKKLADM
Sbjct: 816 KAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADM 875
Query: 901 YGGGDD 906
YGGG+D
Sbjct: 876 YGGGED 881
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 638 bits (1645), Expect = 0.0
Identities = 355/758 (46%), Positives = 471/758 (62%), Gaps = 36/758 (4%)
Query: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIIN 213
L+R KRDWV+ PI++PEN +GPFPQ L +++S++D++ + YS+TGPGAD PP G+F +
Sbjct: 102 LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVE 161
Query: 214 PISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQVWN 273
+G L + KPLDRE+IA++ L HAV NG VE+P++I I V D ND++P+F +
Sbjct: 162 KETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFR 221
Query: 274 GTVPEGSKPGTYVMTVTAIDADDP-NALNGMLRYRIVSQAPSTPSPNMFTINNETGDIIT 332
G+V EG PGT VM VTA D DD NG++ Y I SQ P P MFTI+ TG I
Sbjct: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281
Query: 333 VAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVP 392
+++GLDREKV +YTL IQATDM+G+ G + TA AV+ + D NDN P F + VP
Sbjct: 282 ISSGLDREKVPEYTLTIQATDMDGD---GSTTTAVAVVEILDANDNAPMFDPQKYEAHVP 338
Query: 393 ENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDF 452
EN V V LTVTD D P++PAW A Y I GGD F I T P SN G++T K +DF
Sbjct: 339 ENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDF 398
Query: 453 ETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHA 512
E L V N+ P + P STAT+ V V DVNE P F P K++ +EG+
Sbjct: 399 EAKNQHTLYVEVTNEAPFVLKL---PTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPT 455
Query: 513 GTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPN-VKNNIY 571
G + +TA+DPD+ Q I Y L DPA WL +DP +GQ+T + LDRE V+NNIY
Sbjct: 456 GEPVCVYTAEDPDK-ENQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIY 514
Query: 572 NATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETC-ETPDPNSINITALDYDI 630
LA DNG PP +GTGTL + L+D+ND+ P P++ C ++P +NIT D D+
Sbjct: 515 EVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNIT--DKDL 572
Query: 631 DPNAGPFAFDLPLSPVTIKRNWTI-TRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPP 689
P+ PF L WT GD L+LK KFL+ Y+V + ++D GN
Sbjct: 573 SPHTSPFQAQLTDDSDIY---WTAEVNEEGDTVVLSLK-KFLKQDTYDVHLSLSDHGN-- 626
Query: 690 KSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRR 749
K ++++R VC C + V+ G G G I+ +L ++ LL L+L+ ++ ++
Sbjct: 627 KEQLTVIRATVCDCHGH-----VETCPGPWKG-GFILPVLGAVLALLFLLLVLLLLVR-- 678
Query: 750 DKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRM 809
K+R+ K+ L+ PEDD RDN+ Y EEGGGEEDQDYD++QL + P+ + R
Sbjct: 679 -KKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEV-----VLRN 732
Query: 810 DERP-IHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAG 868
D P I P Y R A +P +IG+FI E LKAA+ DPTAPPYD+LLVFDYEGSGS A
Sbjct: 733 DVAPTIIPTPMYRPRPA--NPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAA 790
Query: 869 SLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGDD 906
SLSSL SS+S +QDYDYLN+WG RFKKLADMYGGG+D
Sbjct: 791 SLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGED 828
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 592 bits (1525), Expect = e-169
Identities = 325/756 (42%), Positives = 458/756 (60%), Gaps = 21/756 (2%)
Query: 154 LQRQKRDWVIPPINLPEN-SRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFII 212
L R +R WVIPPI++ EN R P+P LV+I+SD+ + S+ YS+ GPG D+ P G+F I
Sbjct: 40 LSRVRRAWVIPPISVSENHKRLPYP--LVQIKSDKQQLGSVIYSIQGPGVDEEPRGVFSI 97
Query: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQVW 272
+ +G++ + LDRE+ RF LRA A+D+ G+ +E+P D+ I V+D NDNRP FL + +
Sbjct: 98 DKFTGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQEAF 157
Query: 273 NGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQAPSTPSPNMFTINNETGDIIT 332
G V EG+ PGTYV A DADDP N LR+ I+ Q SP +F+I+ TG+I T
Sbjct: 158 TGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQG----SPELFSIDELTGEIRT 213
Query: 333 VAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVP 392
V GLDRE V Y L +Q DM G+ GL+ TA+A+IT+ D+NDN PEFT F+ E
Sbjct: 214 VQVGLDREVVAVYNLTLQVADMSGD---GLTATASAIITLDDINDNAPEFTRDEFFMEAI 270
Query: 393 ENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDF 452
E + V L V D+D P +P W A + I GDP G+F I+TDP +N+G++++VK +D+
Sbjct: 271 EAVSGVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDY 330
Query: 453 ETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHA 512
E+ + L V+ +N+ PL + A V V V D NE P F NP EG
Sbjct: 331 ESCEHYELKVSVQNEAPLQAAALRAERGQAKVRVHVQDTNEPPVFQENPLRTSLAEGAPP 390
Query: 513 GTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYN 572
GT++ TF+A+DPD Q + Y+K DP +WL++D G+I T VL SP +K Y
Sbjct: 391 GTLVATFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYR 450
Query: 573 ATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVL-PQEAETCETPDPN-SINITALDYDI 630
A LA D+ P + TGTL I +L++ND+AP + P C P + + A D D+
Sbjct: 451 AIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGLLLGATDEDL 510
Query: 631 DPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPK 690
P+ PF F L + RNW+++++N A+L + + E G++ + +++ DSG PP+
Sbjct: 511 PPHGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPRHQVPE-GLHRLSLLLRDSGQPPQ 569
Query: 691 SNISILRVKVCQCDSNGDCTDVDRIV---GAGLGTGAIIAILLCIIILLILVLMFVVWMK 747
L V VC+C +G C + G GL GA++ +L ++LL+LVL+ V
Sbjct: 570 QREQPLNVTVCRCGKDGVCLPGAAALLAGGTGLSLGALVIVLASALLLLVLVLL-VALRA 628
Query: 748 RRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPDTVEPDAIKPVGI 806
R K+ + K LL P+DD+RDN+L YDE+GGGEEDQD YD+SQL+ P + P
Sbjct: 629 RFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEEDQDAYDISQLRHPTALSLPLGPPPLR 688
Query: 807 RRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGST 866
R + +H +P R P DI DFIN+GL+AAD+DP+ PPYD+ L++DYEG GS
Sbjct: 689 RDAPQGRLHPQPP---RVLPTSPLDIADFINDGLEAADSDPSVPPYDTALIYDYEGDGSV 745
Query: 867 AGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYG 902
AG+LSS+ SS +QDYDYL DWGPRF +LADMYG
Sbjct: 746 AGTLSSILSSQGDEDQDYDYLRDWGPRFARLADMYG 781
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 520 bits (1338), Expect = e-147
Identities = 302/707 (42%), Positives = 420/707 (59%), Gaps = 27/707 (3%)
Query: 9 RTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLNVKFSNCNGKRK 68
RT L L L Q + S E C GF + V+ + E Q +LN+ FS+C G K
Sbjct: 4 RTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGNDK 63
Query: 69 VQYESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLKPTLT 128
++YE S P FKV+ DG + A+R+ +++ ++A+ ++ ++ + +
Sbjct: 64 LRYEVSSPY-FKVNSDGGLVALRN--ITAVGKTLFVHARTPHAEDMAELVI-------VG 113
Query: 129 EESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRD 188
+ ++ S + + F R + + RQKR V+ PI +PEN R PFP+++ ++ D D
Sbjct: 114 GKDIQGSLQ-DIFKFAR-----TSPVPRQKRSIVVSPILIPENQRQPFPRDVGKV-VDSD 166
Query: 189 KNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVE 248
+ ++ +TG G DQ P GIF IN +G +SVT+ LDRE IA + L D+NG +E
Sbjct: 167 RPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLE 226
Query: 249 NPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRI 308
P+ + + VID NDNRP F + G V EGS GT VM +TA DADDP N +LRY I
Sbjct: 227 GPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNI 286
Query: 309 VSQAPSTPSPNMFTINNETGDIITVA--AGLDREKVQ--QYTLIIQATDMEGNPTYGLSN 364
Q P PSPNMF I+ E GDI+TV A LDRE ++ +Y LII+A DM G GL+
Sbjct: 287 RQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDV-GLTG 345
Query: 365 TATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISG 424
TATA I + D ND+ P+FT F V E V +IV NLTV DKD P T AW A Y I
Sbjct: 346 TATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIV-NLTVEDKDDPTTGAWRAAYTIIN 404
Query: 425 GDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATV 484
G+P F I T+P +N+G+++VVKP+D+E + L + EN+ PL + + P STATV
Sbjct: 405 GNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATV 464
Query: 485 SVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWL 544
+TV+DVNE P F P+P ++ ++E L G++L T A DPD Q IRY+ DPA WL
Sbjct: 465 HITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWL 524
Query: 545 KIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQ 604
I+P+NG + T AVLDRESP V N++Y A FLA D+G PP +GTGTL I L D+NDNAP
Sbjct: 525 NINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPF 584
Query: 605 VLPQEAETCETPDPNSINIT-ALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQ 663
+ P AE C+ S+ I A D D+ PN PF F++ V K W I+++N A
Sbjct: 585 IYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDK-VWKISKINNTHAL 643
Query: 664 LNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQC-DSNGDC 709
++L ++ L Y +PI++TDSG PP +NI+ LRV+VC C +S DC
Sbjct: 644 VSL-LQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDC 689
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 447 bits (1151), Expect = e-125
Identities = 301/772 (38%), Positives = 423/772 (54%), Gaps = 49/772 (6%)
Query: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFII 212
LQR KR WV + E GP P + R+ SD D + +++Y ++G GA IF+I
Sbjct: 48 LQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGT----IFVI 103
Query: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDINGNQ-VENPIDIVINVIDMNDNRPEFLHQV 271
+ SG + TK LDRE+ A++ L A AVD + N+ +E P + ++ V D+NDN PEFLH+
Sbjct: 104 DDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHET 163
Query: 272 WNGTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDI 330
++ VPE S GT V+ VTA DADDP N L Y I+ P F++ +TG I
Sbjct: 164 YHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQP------YFSVEAQTGII 217
Query: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
T +DRE ++Y ++IQA DM G+ GLS T IT+TDVNDNPP+F +
Sbjct: 218 RTALPNMDREAKEEYHVVIQAKDMGGHMG-GLSGTTKVTITLTDVNDNPPKFPQSVYQMS 276
Query: 391 VPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPI 450
V E V V KD Y I GD F I TD + +G++ + KP+
Sbjct: 277 VSEAAVPGEEVG-RVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPV 335
Query: 451 DFETNRMFVLTVAAENQVPLAKGIQHPP-QSTATVSVTVIDVNENPYFAPNPKIIRQEEG 509
DFET R + L V A N K I + P + T TV ++V D +E P F I +E
Sbjct: 336 DFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQEN 395
Query: 510 LHAGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRESPNVK 567
AGT++ A+DPD IRY+ + +D + I+P +G I T LDRE +
Sbjct: 396 AAAGTVVGRVHAKDPDA-ANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDRE----E 450
Query: 568 NNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQ-VLPQEAETCETPDPNSIN---- 622
N T A++ + I +LD+NDNAP+ P E CE+ ++
Sbjct: 451 TAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPI 510
Query: 623 --ITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLK---IKFLEAGIYE 677
I+A D D N F F LP + N+T+ + A + + + +Y
Sbjct: 511 VTISADDKDDTANGPRFIFSLP-PEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYL 569
Query: 678 VPIIITDSGNPPKSNISILRVKVCQCDSNG---DCTDVDRIVGAGLGTGAIIAILLCIII 734
+PI+I+D G PP S+ + L +KVC CD NG C I+ AGL TGA+IAIL CI+I
Sbjct: 570 LPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVI 629
Query: 735 LLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQP 793
LL++V++FV ++R+ KE L++ E+DVR+NI+ YD+EGGGEED + +D++ LQ P
Sbjct: 630 LLVIVVLFVT-LRRQKKE----PLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNP 684
Query: 794 DTVEPDAIKPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYD 853
D + I R D +P + P AP+ D+ DFIN ++ ADNDPTAPPYD
Sbjct: 685 DGINGF------IPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYD 738
Query: 854 SLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGD 905
S+ ++ YEG GS AGSLSSL S+++ + DYDYL +WGPRFKKLAD+YG D
Sbjct: 739 SIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLYGSKD 790
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 439 bits (1130), Expect = e-123
Identities = 293/771 (38%), Positives = 420/771 (54%), Gaps = 53/771 (6%)
Query: 156 RQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFIINP 214
R KR WV + E G P + ++ SD DK + S++Y ++G GA + IFII+
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGA----SSIFIIDE 99
Query: 215 ISGQLSVTKPLDREQIARFHLRAHAVD-INGNQVENPIDIVINVIDMNDNRPEFLHQVWN 273
+G + TK LDRE+ A + LRA A+D + VE + VI + D+NDN P+FL +
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 274 GTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDIIT 332
VPE S GT V+ VTA DADDP N + Y I+ P F++ +TG I T
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP------YFSVEPKTGVIKT 213
Query: 333 VAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVP 392
+DRE QY L+IQA DM G GLS T + +T+TDVNDNPP F ++ VP
Sbjct: 214 ALPNMDREAKDQYLLVIQAKDMVGQ-NGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVP 272
Query: 393 ENR-VDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPID 451
E+ V +VA + D D Y+I GD G F I D + +G++T+ K +D
Sbjct: 273 ESLPVASVVARIKAADADIGANAEME--YKIVDGDGLGIFKISVDKETQEGIITIQKELD 330
Query: 452 FETNRMFVLTVAAENQVPLAKGIQHPPQS-TATVSVTVIDVNENPYFAPNPKIIRQEEGL 510
FE + L + A N+ + + P S T TV + V DV+E P F+ + E
Sbjct: 331 FEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEAT 390
Query: 511 HAGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRESPNVKN 568
G ++ T A DPD +RY+ + +D + ID +G ITT LDRE+ N
Sbjct: 391 QVGNIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET----N 445
Query: 569 NIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQ-VLPQEAETCETPDPNSI--NITA 625
I+N T LA ++ P G G + I +LDINDNAP+ + E CE P + I+A
Sbjct: 446 AIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISA 505
Query: 626 LDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLK---IKFLEAGIYEVPIII 682
+D D N F F L + T N+++ + A + + + E +Y +PI I
Sbjct: 506 VDKDEPSNGHQFYFSLT-TDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFI 564
Query: 683 TDSGNPPKSNISILRVKVCQCDSNG---DCTDVDRIVGAGLGTGAIIAILLCIIILLILV 739
DSG+P S+ + L ++VC CD++G C ++ AGL TGA+IAIL C++ LL+L+
Sbjct: 565 VDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLI 624
Query: 740 LMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPDTVEP 798
L+ +V M+RR KE L+ D E D+R+NI++YD+EGGGEED + +D++ L+ + +
Sbjct: 625 LL-IVTMRRRKKE----PLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRD 679
Query: 799 DAIKPVGIRRMDERPIHAEPQY---PVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSL 855
+ R + E Q+ P + P +FI E LK AD DP APPYDSL
Sbjct: 680 TKTR---------RDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADVDPGAPPYDSL 730
Query: 856 LVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGDD 906
+ +EG+GS A SLSSL+S SS +Q+YDYL+DWGPRFK+LADMYG G +
Sbjct: 731 QTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQE 781
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 439 bits (1130), Expect = e-123
Identities = 293/771 (38%), Positives = 420/771 (54%), Gaps = 53/771 (6%)
Query: 156 RQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFIINP 214
R KR WV + E G P + ++ SD DK + S++Y ++G GA + IFII+
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGA----SSIFIIDE 99
Query: 215 ISGQLSVTKPLDREQIARFHLRAHAVD-INGNQVENPIDIVINVIDMNDNRPEFLHQVWN 273
+G + TK LDRE+ A + LRA A+D + VE + VI + D+NDN P+FL +
Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159
Query: 274 GTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDIIT 332
VPE S GT V+ VTA DADDP N + Y I+ P F++ +TG I T
Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQP------YFSVEPKTGVIKT 213
Query: 333 VAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVP 392
+DRE QY L+IQA DM G GLS T + +T+TDVNDNPP F ++ VP
Sbjct: 214 ALPNMDREAKDQYLLVIQAKDMVGQ-NGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVP 272
Query: 393 ENR-VDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPID 451
E+ V +VA + D D Y+I GD G F I D + +G++T+ K +D
Sbjct: 273 ESLPVASVVARIKAADADIGANAEME--YKIVDGDGLGIFKISVDKETQEGIITIQKELD 330
Query: 452 FETNRMFVLTVAAENQVPLAKGIQHPPQS-TATVSVTVIDVNENPYFAPNPKIIRQEEGL 510
FE + L + A N+ + + P S T TV + V DV+E P F+ + E
Sbjct: 331 FEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEAT 390
Query: 511 HAGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRESPNVKN 568
G ++ T A DPD +RY+ + +D + ID +G ITT LDRE+ N
Sbjct: 391 QVGNIIGTVAAHDPDS-SNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET----N 445
Query: 569 NIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQ-VLPQEAETCETPDPNSI--NITA 625
I+N T LA ++ P G G + I +LDINDNAP+ + E CE P + I+A
Sbjct: 446 AIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISA 505
Query: 626 LDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLK---IKFLEAGIYEVPIII 682
+D D N F F L + T N+++ + A + + + E +Y +PI I
Sbjct: 506 VDKDEPSNGHQFYFSLT-TDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFI 564
Query: 683 TDSGNPPKSNISILRVKVCQCDSNG---DCTDVDRIVGAGLGTGAIIAILLCIIILLILV 739
DSG+P S+ + L ++VC CD++G C ++ AGL TGA+IAIL C++ LL+L+
Sbjct: 565 VDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLI 624
Query: 740 LMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPDTVEP 798
L+ +V M+RR KE L+ D E D+R+NI++YD+EGGGEED + +D++ L+ + +
Sbjct: 625 LL-IVTMRRRKKE----PLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRD 679
Query: 799 DAIKPVGIRRMDERPIHAEPQY---PVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSL 855
+ R + E Q+ P + P +FI E LK AD DP APPYDSL
Sbjct: 680 TKTR---------RDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADVDPGAPPYDSL 730
Query: 856 LVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGDD 906
+ +EG+GS A SLSSL+S SS +Q+YDYL+DWGPRFK+LADMYG G +
Sbjct: 731 QTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQE 781
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 429 bits (1103), Expect = e-120
Identities = 290/771 (37%), Positives = 427/771 (55%), Gaps = 55/771 (7%)
Query: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFII 212
L RQKR W+ L E G Q + ++ SD+DK + SL+Y ++G GA +FII
Sbjct: 49 LHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGT----LFII 104
Query: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDING-NQVENPIDIVINVIDMNDNRPEFLHQV 271
+ +G + T+ +DRE+ A + LRA A++ VE + VI + D+NDN P F ++
Sbjct: 105 DEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEI 164
Query: 272 WNGTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDI 330
+ +VPE S GT V+ VTA DADDP+ N + Y I+ P F++ ETG I
Sbjct: 165 YTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQP------YFSVEPETGII 218
Query: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
T ++RE +QY ++IQA DM G GLS T T IT+TDVNDNPP F T +
Sbjct: 219 RTALPNMNRENREQYQVVIQAKDM-GGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLR 277
Query: 391 VPENR-VDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKP 449
V E+ V + ++ TD D YRI GD T F I T+ ++ +G++TV KP
Sbjct: 278 VLESSPVGTAIGSVKATDADTGKNA--EVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKP 335
Query: 450 IDFETNRMFVLTVAAEN-QVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEE 508
+D+E+ R++ L V AEN V P + T V +++ DV+E P F+ + + E
Sbjct: 336 LDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHE 395
Query: 509 GLHAGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRESPNV 566
+ GT++ T A+DPD + IR++ + +D I NG + T LDRE
Sbjct: 396 DIEVGTIIGTVMARDPDS-ISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDREL--- 451
Query: 567 KNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQ-VLPQEAETCETPDPNSI--NI 623
+ +N T +A++ P + + + +LD+NDNAPQ + + CE P + I
Sbjct: 452 -SQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTI 510
Query: 624 TALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFL---EAGIYEVPI 680
+A+D D DP G F S + N+T+ + A++ + E Y +P+
Sbjct: 511 SAVDKD-DPLGGQKFF---FSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPV 566
Query: 681 IITDSGNPPKSNISILRVKVCQCDSNGD---CTDVDRIVGAGLGTGAIIAILLCIIILLI 737
+I+D+ P +S+ L ++VC CDS G+ C+ ++ AGL TGA+IAILLCIIILL+
Sbjct: 567 VISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLV 626
Query: 738 LVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPDTV 796
+V++F ++R KE LI ++D+RDNI+ Y++EGGGEED Q +D+ L+ P +
Sbjct: 627 IVVLFAALKRQRKKEP-----LILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAI 681
Query: 797 EPDAIKPVGIRRMDERPIHAEPQYPVRSA--APHPGDIGDFINEGLKAADNDPTAPPYDS 854
E ++ R I E + R AP D+ DFINE LK D DPTAPPYDS
Sbjct: 682 EEKKLR---------RDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDS 732
Query: 855 LLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGD 905
L + YEG+ S A SLSSL S ++ G+Q+YDYL +WGPRF KLA+MYGGG+
Sbjct: 733 LATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGE 783
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 429 bits (1103), Expect = e-120
Identities = 267/717 (37%), Positives = 392/717 (54%), Gaps = 44/717 (6%)
Query: 73 SSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLKPTLTEESV 132
SS+PA F++ EDG +Y LSSE F I+ D + +E+ ++ V LS + +
Sbjct: 64 SSDPA-FRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKS---- 118
Query: 133 KESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLS 192
P++ L+R KR W P +L ENS GPFPQ + +I+SD +N +
Sbjct: 119 -----------PKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYT 167
Query: 193 LRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPID 252
+ YS++GPG D+ P +F I +G + T+ +DRE+ +F L +A +G E P+
Sbjct: 168 IFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLP 227
Query: 253 IVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQA 312
++I + D NDN P F H+V TVPE + GT V VTA D D+P+ L+ L+Y+I+ Q
Sbjct: 228 LIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQI 287
Query: 313 PSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITV 372
P P F+I+ +TG I T LDREK Y LI++ DM G P +GL NT T I++
Sbjct: 288 PD--HPKHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQP-FGLFNTGTITISL 344
Query: 373 TDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFA 432
D NDNPP FT ++ EV ENR+D+ + + V D+D P+TP AVY+I G+ G F
Sbjct: 345 EDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFI 404
Query: 433 IQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGI--QHPPQSTATVSVTVID 490
I TDPN+N+G++ VVKP+++E NR +L V N+ +K Q P T TV+V +ID
Sbjct: 405 ISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIID 464
Query: 491 VNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVN 550
+E P P K+I+ ++G AG L + A DP+ + +RY KL D NW +I+
Sbjct: 465 SDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHT 524
Query: 551 GQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEA 610
G + T+ VLDRES VKNN YN + +A D S TGTL ++L D ND+APQ+ +E
Sbjct: 525 GDLRTLKVLDRESKFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYNDHAPQI-DKEV 581
Query: 611 ETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKF 670
C+ + ++ + +D D N PF F L S +NW I +G A L + +
Sbjct: 582 TICQNNEDFAV-LKPVDPDGPENGPPFQFFLDNS---ASKNWNIEEKDGKTAILRQR-QN 636
Query: 671 LEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIV-----GAGLGTGAI 725
L+ Y VPI I D ++ +L V+VC C + +C D+ LG AI
Sbjct: 637 LDYNYYSVPIQIKDRHGLVATH--MLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAI 694
Query: 726 IAILL-CIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEE 781
+A++L +++L IL F V KR K+ PED + N++ + EG GEE
Sbjct: 695 LAMVLGSVLLLCILFTCFCVTAKRTVKK-------CFPEDIAQQNLIVSNTEGPGEE 744
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 429 bits (1103), Expect = e-120
Identities = 267/717 (37%), Positives = 392/717 (54%), Gaps = 44/717 (6%)
Query: 73 SSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLKPTLTEESV 132
SS+PA F++ EDG +Y LSSE F I+ D + +E+ ++ V LS + +
Sbjct: 64 SSDPA-FRILEDGSIYTTHDLILSSERKSFSIFLSDGQRREQQEIKVVLSARENKS---- 118
Query: 133 KESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLS 192
P++ L+R KR W P +L ENS GPFPQ + +I+SD +N +
Sbjct: 119 -----------PKKRHTKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYT 167
Query: 193 LRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPID 252
+ YS++GPG D+ P +F I +G + T+ +DRE+ +F L +A +G E P+
Sbjct: 168 IFYSISGPGVDKEPFNLFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLP 227
Query: 253 IVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQA 312
++I + D NDN P F H+V TVPE + GT V VTA D D+P+ L+ L+Y+I+ Q
Sbjct: 228 LIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQI 287
Query: 313 PSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITV 372
P P F+I+ +TG I T LDREK Y LI++ DM G P +GL NT T I++
Sbjct: 288 PD--HPKHFSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQP-FGLFNTGTITISL 344
Query: 373 TDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFA 432
D NDNPP FT ++ EV ENR+D+ + + V D+D P+TP AVY+I G+ G F
Sbjct: 345 EDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFI 404
Query: 433 IQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGI--QHPPQSTATVSVTVID 490
I TDPN+N+G++ VVKP+++E NR +L V N+ +K Q P T TV+V +ID
Sbjct: 405 ISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIID 464
Query: 491 VNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVN 550
+E P P K+I+ ++G AG L + A DP+ + +RY KL D NW +I+
Sbjct: 465 SDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDEDNWFEINQHT 524
Query: 551 GQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEA 610
G + T+ VLDRES VKNN YN + +A D S TGTL ++L D ND+APQ+ +E
Sbjct: 525 GDLRTLKVLDRESKFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYNDHAPQI-DKEV 581
Query: 611 ETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKF 670
C+ + ++ + +D D N PF F L S +NW I +G A L + +
Sbjct: 582 TICQNNEDFAV-LKPVDPDGPENGPPFQFFLDNS---ASKNWNIEEKDGKTAILRQR-QN 636
Query: 671 LEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIV-----GAGLGTGAI 725
L+ Y VPI I D ++ +L V+VC C + +C D+ LG AI
Sbjct: 637 LDYNYYSVPIQIKDRHGLVATH--MLTVRVCDCSTPSECRMKDKSTRDVRPNVILGRWAI 694
Query: 726 IAILL-CIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEE 781
+A++L +++L IL F V KR K+ PED + N++ + EG GEE
Sbjct: 695 LAMVLGSVLLLCILFTCFCVTAKRTVKK-------CFPEDIAQQNLIVSNTEGPGEE 744
Score = 30.4 bits (67), Expect = 7.8
Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Query: 853 DSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLA 898
D + ++YEG GS AGS+ + E+ ++L+ P+F+ LA
Sbjct: 845 DYVCSYNYEGKGSLAGSVGCCSDRQE--EEGLEFLDHLEPKFRTLA 888
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 429 bits (1103), Expect = e-120
Identities = 290/772 (37%), Positives = 430/772 (55%), Gaps = 53/772 (6%)
Query: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFII 212
L R KR WV + + E GP P + R+ +D D + ++Y ++G GA IF I
Sbjct: 56 LNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGT----IFQI 111
Query: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDINGNQ-VENPIDIVINVIDMNDNRPEFLHQV 271
N ++G + K LDRE+ A + L A AVD ++ +E P + +I V D+NDN PEFL+
Sbjct: 112 NDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGP 171
Query: 272 WNGTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDI 330
++ TVPE S GT V VTA DADDP N L Y I+ P F+I ET I
Sbjct: 172 YHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQP------YFSIEPETAII 225
Query: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
T +DRE ++Y ++IQA DM G+ + GLS T T +T+TDVNDNPP+F ++
Sbjct: 226 KTALPNMDREAKEEYLVVIQAKDMGGH-SGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFS 284
Query: 391 VPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPI 450
VPE+ V + A V DQ + Y I GD T F I +D + DG++ + KP+
Sbjct: 285 VPEDVV-LGTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGIIRLRKPL 343
Query: 451 DFETNRMFVLTVAAENQV--PLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEE 508
DFET + + L V A N P G + P + TATV + V D +E P F+ ++ E
Sbjct: 344 DFETKKSYTLKVEAANVHIDPRFSG-RGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHE 402
Query: 509 GLHAGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRESPNV 566
+++ TA+DPD IR++ + +D I+ +G+IT LDRE
Sbjct: 403 NAALNSVIGQVTARDPD-ITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDREL--- 458
Query: 567 KNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQ-EAETCETPDPNSI--NI 623
+ +N T +A++ + I +LD+NDNAP+ + EA CE P + +
Sbjct: 459 -SVWHNITIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTV 517
Query: 624 TALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLK---IKFLEAGIYEVPI 680
+A+D D N F + L L + N+TI + + + K + +Y +PI
Sbjct: 518 SAMDKDDPKNGHYFLYSL-LPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPI 576
Query: 681 IITDSGNPPKSNISILRVKVCQCDSNG---DCTDVDRIVGAGLGTGAIIAILLCIIILLI 737
II+DSGNPP S+ S L ++VC C ++G C ++ GL GA+IAIL CII+LL+
Sbjct: 577 IISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACIILLLV 636
Query: 738 LVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPDTV 796
+V++FV + +++ L+I ++DVR+NI++YD+EGGGEED + +D++ LQ PD +
Sbjct: 637 IVVLFVTLRRHKNEP-----LIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGI 691
Query: 797 EPDAIKPVGIRRMDERPIHAEPQY-PVRSAAPHPG--DIGDFINEGLKAADNDPTAPPYD 853
+ R D +P + Q+ P + AP P D+ +FIN L ADNDPTAPPYD
Sbjct: 692 NGF------LPRKDIKP---DLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPTAPPYD 742
Query: 854 SLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGD 905
S+ ++ YEG GS AGSLSSL S++S +Q++DYL+DWGPRFK+L ++Y G+
Sbjct: 743 SIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGE 794
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 426 bits (1095), Expect = e-119
Identities = 291/772 (37%), Positives = 421/772 (54%), Gaps = 54/772 (6%)
Query: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFII 212
L R KR W+ L E G Q + ++ SD+D+ + SL+Y ++G GA +FII
Sbjct: 48 LNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGD----LFII 103
Query: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDIN-GNQVENPIDIVINVIDMNDNRPEFLHQV 271
N +G + TK LDRE+ + LRA A++ G VE + +I + D+NDN P F +V
Sbjct: 104 NENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEV 163
Query: 272 WNGTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDI 330
+ TVPE S GT+V+ VTA DADDP N + Y I+ P F++ +ETG I
Sbjct: 164 YTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQP------YFSVESETGII 217
Query: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
T +DRE +QY ++IQA DM G GLS T T IT+TDVNDNPP F T+ +
Sbjct: 218 KTALLNMDRENREQYQVVIQAKDM-GGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFK 276
Query: 391 VPENRVD-IIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKP 449
PE+ + + +D D Y I+ G+ F + TD + +G++TV K
Sbjct: 277 TPESSPPGTPIGRIKASDADVGENA--EIEYSITDGEGLDMFDVITDQETQEGIITVKKL 334
Query: 450 IDFETNRMFVLTVAAENQVPLAKGIQHPP-QSTATVSVTVIDVNENPYFAPNPKIIRQEE 508
+DFE +++ L V A N + + P + +ATV + V DV+E P F+ I++ E
Sbjct: 335 LDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIRE 394
Query: 509 GLHAGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRESPNV 566
T + + TAQDPD + ++Y+ + +D ID NG I T +LDRE+
Sbjct: 395 DAQINTTIGSVTAQDPDA-ARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLW 453
Query: 567 KNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLP-QEAETCETPDPNSI--NI 623
+N T +A++ P S L I +LD+NDNAP+ E CE + + +
Sbjct: 454 ----HNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTL 509
Query: 624 TALDYDIDPNAGPFAFDLPLSPVTIK-RNWTITRLNGDFAQLNLKIKFL---EAGIYEVP 679
A+D D DP +G F L+P N+TI + A + + E Y +P
Sbjct: 510 HAVDKD-DPYSG-HQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLP 567
Query: 680 IIITDSGNPPKSNISILRVKVCQCDSNGD---CTDVDRIVGAGLGTGAIIAILLCIIILL 736
++I+D+ P +S+ + V+VC CD +G+ C I GL TGA++AILLCI+ILL
Sbjct: 568 VVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVAILLCIVILL 627
Query: 737 ILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPDT 795
+ V++F ++R KE LI ++D+RDNI+ Y++EGGGEED Q +D+ L+ P+
Sbjct: 628 VTVVLFAALRRQRKKEP-----LIISKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPEA 682
Query: 796 VEPDAIKPVGIRRMDERPIHAEPQYPVRSA--APHPGDIGDFINEGLKAADNDPTAPPYD 853
+E + ++ R I E + R A D+ DFIN+ LK D DPTAPPYD
Sbjct: 683 IEDNKLR---------RDIVPEALFLPRRTPTARDNTDVRDFINQRLKENDTDPTAPPYD 733
Query: 854 SLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGD 905
SL + YEG+GS A SLSSL S ++ +QDYDYL+DWGPRFKKLADMYGG D
Sbjct: 734 SLATYAYEGTGSVADSLSSLESVTTDADQDYDYLSDWGPRFKKLADMYGGVD 785
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 423 bits (1088), Expect = e-118
Identities = 284/771 (36%), Positives = 419/771 (54%), Gaps = 52/771 (6%)
Query: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFII 212
L+R KR W+ L E G Q + ++ +D+DK + +L+Y +TG GA +F+I
Sbjct: 48 LRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAGS----LFVI 103
Query: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDIN-GNQVENPIDIVINVIDMNDNRPEFLHQV 271
+ +G + K LDRE+ + + LRA A+D G QVE + +I + D+NDN P+F +
Sbjct: 104 DENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDL 163
Query: 272 WNGTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDI 330
+ +VPE S GT V+ VTA DADD N N + Y I+ P F+++ E+G I
Sbjct: 164 YTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQP------YFSVDPESGII 217
Query: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
T + RE +QY ++IQA DM G GLS T T IT+TDVN+NPP F T+
Sbjct: 218 KTALPDMSRENREQYQVVIQAKDM-GGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFN 276
Query: 391 VPEN-RVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKP 449
PE+ + + + D D Y I+ GD F + TD ++ +G++TV +
Sbjct: 277 SPESVPLGTHLGRIKANDPDVGENAEME--YSIAEGDGADMFDVITDKDTQEGIITVKQN 334
Query: 450 IDFETNRMFVLTVAAENQVPLAKGIQHPP-QSTATVSVTVIDVNENPYFAPNPKIIRQEE 508
+DFE ++ L V A N P + + P + TA V ++V D++E P F +I +E
Sbjct: 335 LDFENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDE 394
Query: 509 GLHAGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRESPNV 566
+ G+++ TA DPD I+Y+ + +D I NG I T+ LDRES
Sbjct: 395 DVKEGSIIGQVTAYDPDA-RNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRES--- 450
Query: 567 KNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQ-VLPQEAETCETPDPNSI--NI 623
+ +N T A++ P S + I +LDIND+AP+ + E CE P + +
Sbjct: 451 -SPWHNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTV 509
Query: 624 TALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLK---IKFLEAGIYEVPI 680
+ +D D P F F+ P+ T+ N+TI + A + + + Y +PI
Sbjct: 510 SVMDKDDPPRGHKFFFE-PVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLPI 568
Query: 681 IITDSGNPPKSNISILRVKVCQCDSNGD---CTDVDRIVGAGLGTGAIIAILLCIIILLI 737
+I D+ P +S+ L ++VC CD+ G+ CT I+ AGL TGA++AILLC++ILLI
Sbjct: 569 LIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLI 628
Query: 738 LVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPDTV 796
LV++F ++R KE LI +DDVRDNI+ Y++EGGGEED Q +D+ L+ P+
Sbjct: 629 LVVLFAALKRQRKKEP-----LIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAR 683
Query: 797 EPDAIKPVGIRRMDERPIHAEPQYPVRSAAP--HPGDIGDFINEGLKAADNDPTAPPYDS 854
E ++ R + E + +R P D+ DFI+ LK D DP+APPYDS
Sbjct: 684 EDSKLR---------RDVMPETIFQIRRTVPLWENIDVQDFIHRRLKENDADPSAPPYDS 734
Query: 855 LLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGD 905
L + YEG+ S A SLSSL S ++ QDYDYL+DWGPRFKKLADMYGG D
Sbjct: 735 LATYAYEGNDSIADSLSSLESLTADCNQDYDYLSDWGPRFKKLADMYGGDD 785
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 419 bits (1076), Expect = e-117
Identities = 284/772 (36%), Positives = 418/772 (54%), Gaps = 58/772 (7%)
Query: 153 HLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNL-SLRYSVTGPGADQPPTGIFI 211
H QR KR WV + E G PQ + ++ SD DK +++Y+++G GA +F
Sbjct: 48 HFQRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAGT----VFT 103
Query: 212 INPISGQLSVTKPLDREQIARFHLRAHAVDINGNQ-VENPIDIVINVIDMNDNRPEFLHQ 270
I+ +G + + LDRE+ + LRA AVDI + +E + +I V D+NDN P+FL
Sbjct: 104 IDETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLDG 163
Query: 271 VWNGTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGD 329
+ TVPE S G YV+ V A DADDP N + Y I+ P F+I+ +TG
Sbjct: 164 PYVATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQP------YFSIDPKTGV 217
Query: 330 IITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYG 389
I T +DRE +QY ++IQA DM G GL+ T IT+TDVNDNPP F F+
Sbjct: 218 IRTALPNMDREVKEQYQVLIQAKDM-GGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHL 276
Query: 390 EVPENR-VDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVK 448
+VPE+ + + + D D Y I GD F I TD ++ +G++ + K
Sbjct: 277 KVPESSPIGSAIGRIRAVDPDFGQNA--EIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKK 334
Query: 449 PIDFETNRMFVLTVAAEN-QVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQE 507
P+DFET + + V A N + P + TATV ++V+DV+E P F+ +
Sbjct: 335 PLDFETKKAYTFKVEASNLHLDHRFHSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVY 394
Query: 508 EGLHAGTMLTTFTAQDPDRYMQQNIRY--TKLSDPANWLKIDPVNGQITTIAVLDRESPN 565
E GT++ TAQD D +RY SD ++ ID G I T +LDRES
Sbjct: 395 EDTPVGTIIGAVTAQDLD-VGSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRESTA 453
Query: 566 VKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQV-LPQEAETCETPDPNSIN-- 622
YN + +AS P ++ + I +LD+N+ P++ +P E CE P I
Sbjct: 454 Q----YNFSIIASKVSNPLLTSKVNILINVLDVNEFPPEISVPYETAVCENAKPGQIIQI 509
Query: 623 ITALDYDIDPNAGPFAFDLPLSP-VTIKRNWTITRLNGDFAQLNLK---IKFLEAGIYEV 678
++A D D+ P F+F L SP IK N+T+ + A + + + +Y +
Sbjct: 510 VSAADRDLSPAGQQFSFRL--SPEAAIKPNFTVRDFRNNTAGIETRRNGYSRRQQELYFL 567
Query: 679 PIIITDSGNPPKSNISILRVKVCQCDSNG---DCTDVDRIVGAGLGTGAIIAILLCIIIL 735
P++I DS P +S+ + + ++VC+CDS+G C + GL TGA+IAILLCI+IL
Sbjct: 568 PVVIEDSSYPVQSSTNTMTIRVCRCDSDGTILSCNVEAIFLPVGLSTGALIAILLCIVIL 627
Query: 736 LILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEED-QDYDLSQLQQPD 794
L +V+++V +++ K+ L+ ++D+RDN++ YD+EGGGEED Q +D+ L+ P
Sbjct: 628 LAIVVLYVALRRQKKKDT-----LMTSKEDIRDNVIHYDDEGGGEEDTQAFDIGALRNPK 682
Query: 795 TVEPDAI----KPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAP 850
+E + I KP + +RP P+ DI DFI++ L+ D DPTAP
Sbjct: 683 VIEENKIRRDIKPDSLCLPRQRP-------PMEDNT----DIRDFIHQRLQENDVDPTAP 731
Query: 851 PYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYG 902
PYDSL + YEGSGS A SLSS++S ++ +QDYDYL DWGPRFK LADM+G
Sbjct: 732 PYDSLATYAYEGSGSVAESLSSIDSLTTEADQDYDYLTDWGPRFKVLADMFG 783
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 418 bits (1074), Expect = e-116
Identities = 279/854 (32%), Positives = 429/854 (50%), Gaps = 55/854 (6%)
Query: 73 SSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLKPTLTEESV 132
SS+P DF+V DG VY R+ LS + F I+ DK Q + +V V L ++ V
Sbjct: 66 SSDP-DFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLE-----HQKKV 119
Query: 133 KESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLS 192
++ E V L+R KR W P ++ ENS GPFP L ++ SD +N +
Sbjct: 120 SKTRHTRETV-----------LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYT 168
Query: 193 LRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPID 252
+ YS++G G D+ P +F I +G L T+P+DRE+ F L A+A +G + P+
Sbjct: 169 VFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLP 228
Query: 253 IVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQA 312
+ I V D NDN P F ++N V E S+PGT V V A D D+P+ ++ L+Y I+ Q
Sbjct: 229 LPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQT 288
Query: 313 PSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITV 372
P SP +F+++ TG I TV+ LDRE V +Y+LI++ DM+G +GL T+T +ITV
Sbjct: 289 PR--SPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQ-FFGLIGTSTCIITV 345
Query: 373 TDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFA 432
TD NDN P F + V EN ++ + + + DKD +T W + I G+ G F
Sbjct: 346 TDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFK 405
Query: 433 IQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQ-STATVSVTVIDV 491
I TD +N+G+++VVKP+++E NR L + N+ P A+ I + A V+V V D+
Sbjct: 406 ISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDL 465
Query: 492 NENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNG 551
+E P P + +R +E L G+ + + A DP+ +RY KL DP W+ ID ++G
Sbjct: 466 DEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISG 525
Query: 552 QITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAE 611
I T +LDRE KN +YN T LA D S TGTL + + D+NDN P++L +
Sbjct: 526 SIITSKILDREVETPKNELYNITVLAIDKD--DRSCTGTLAVNIEDVNDNPPEILQEYVV 583
Query: 612 TCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFL 671
C+ P +I A+D D + PF F LP + I R W++T++N A+L+ +
Sbjct: 584 ICK-PKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQ---K 639
Query: 672 EAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLC 731
AG E I IT ++ +LRV +C+C C R G LG AI+AILL
Sbjct: 640 NAGFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLG 699
Query: 732 IIILLILVLMFVVWM------KRRDKERQAKQLLID----PEDDVRDNILKYDEE----- 776
I +L ++L V + KR ++ + L+I P DD + + +
Sbjct: 700 IALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNS 759
Query: 777 --------GGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRMDE--RPIHAEPQYPVRSAA 826
G G ++ + ++ + ++ + G + R H E + +
Sbjct: 760 SQGFCGTMGSGMKNGGQETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYS 819
Query: 827 PHPGDIGDFINEGL-KAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYD 885
+ E L + N+ P D +L ++YEG GS AGS+ + E D
Sbjct: 820 EWHSFTQPRLGEKLHRCNQNEDRMPSQDYVLTYNYEGRGSPAGSVGCCSEKQE--EDGLD 877
Query: 886 YLNDWGPRFKKLAD 899
+LN+ P+F LA+
Sbjct: 878 FLNNLEPKFITLAE 891
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 413 bits (1062), Expect = e-115
Identities = 259/719 (36%), Positives = 380/719 (52%), Gaps = 46/719 (6%)
Query: 73 SSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLS-----LKPTL 127
SS+P DF++ EDG VY + LSSE F I + E QEK ++ V L LK
Sbjct: 66 SSDP-DFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVLKKRH 124
Query: 128 TEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDR 187
T+E V L+R KR W P ++ ENS GPFP L +++SD
Sbjct: 125 TKEKV---------------------LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDT 163
Query: 188 DKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQV 247
+N ++ YS+ GPG DQ P +F + +G L T+P+DREQ F + A A +G
Sbjct: 164 AQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTP 223
Query: 248 ENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYR 307
E P+ ++I + D NDN P F + + T+ E + GT V V A D D+P+ ++ L+Y
Sbjct: 224 ELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYS 283
Query: 308 IVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTAT 367
I+ Q P PSP +F+++ TG I T ++ LDRE + +Y L I+ DM+G +GL T+T
Sbjct: 284 IIGQVP--PSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQ-YFGLQTTST 340
Query: 368 AVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDP 427
+I + DVND+ P FT ++ V EN VD+ + +TV DKD +T W A Y I G+
Sbjct: 341 CIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNE 400
Query: 428 TGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAK-GIQHPPQSTATVSV 486
G F I TD +N+G++ VVKP+++E + +L + N+ P ++ STATV+V
Sbjct: 401 NGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTV 460
Query: 487 TVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKI 546
V D +E P P + +R +E GT + A DP+ IRY KL+DP W+ I
Sbjct: 461 NVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTI 520
Query: 547 DPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVL 606
D G I LDRE+ +KN IYN T LASD G + TGTL I L D+NDN+P +
Sbjct: 521 DENTGSIKVFRSLDREAETIKNGIYNITVLASDQG--GRTCTGTLGIILQDVNDNSPFIP 578
Query: 607 PQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNL 666
+ C+ P +S I A+D D + PF F L S ++R W + +N A+L+
Sbjct: 579 KKTVIICK-PTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSY 637
Query: 667 KIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTD-VDRIVGAG---LGT 722
+ G Y VPI + D S+++ L V +C C + DCT VD +G G LG
Sbjct: 638 Q-NDPPFGSYVVPITVRD--RLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGK 694
Query: 723 GAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEE 781
AI+AILL I +L ++ V +KQ + P+D + N++ + E G++
Sbjct: 695 WAILAILLGIALLFCILFTLVC-----GASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 413 bits (1062), Expect = e-115
Identities = 259/719 (36%), Positives = 380/719 (52%), Gaps = 46/719 (6%)
Query: 73 SSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLS-----LKPTL 127
SS+P DF++ EDG VY + LSSE F I + E QEK ++ V L LK
Sbjct: 66 SSDP-DFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVLKKRH 124
Query: 128 TEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDR 187
T+E V L+R KR W P ++ ENS GPFP L +++SD
Sbjct: 125 TKEKV---------------------LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDT 163
Query: 188 DKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQV 247
+N ++ YS+ GPG DQ P +F + +G L T+P+DREQ F + A A +G
Sbjct: 164 AQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTP 223
Query: 248 ENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYR 307
E P+ ++I + D NDN P F + + T+ E + GT V V A D D+P+ ++ L+Y
Sbjct: 224 ELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYS 283
Query: 308 IVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTAT 367
I+ Q P PSP +F+++ TG I T ++ LDRE + +Y L I+ DM+G +GL T+T
Sbjct: 284 IIGQVP--PSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQ-YFGLQTTST 340
Query: 368 AVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDP 427
+I + DVND+ P FT ++ V EN VD+ + +TV DKD +T W A Y I G+
Sbjct: 341 CIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNE 400
Query: 428 TGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAK-GIQHPPQSTATVSV 486
G F I TD +N+G++ VVKP+++E + +L + N+ P ++ STATV+V
Sbjct: 401 NGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTV 460
Query: 487 TVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKI 546
V D +E P P + +R +E GT + A DP+ IRY KL+DP W+ I
Sbjct: 461 NVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTI 520
Query: 547 DPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVL 606
D G I LDRE+ +KN IYN T LASD G + TGTL I L D+NDN+P +
Sbjct: 521 DENTGSIKVFRSLDREAETIKNGIYNITVLASDQG--GRTCTGTLGIILQDVNDNSPFIP 578
Query: 607 PQEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNL 666
+ C+ P +S I A+D D + PF F L S ++R W + +N A+L+
Sbjct: 579 KKTVIICK-PTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSY 637
Query: 667 KIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTD-VDRIVGAG---LGT 722
+ G Y VPI + D S+++ L V +C C + DCT VD +G G LG
Sbjct: 638 Q-NDPPFGSYVVPITVRD--RLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGK 694
Query: 723 GAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEE 781
AI+AILL I +L ++ V +KQ + P+D + N++ + E G++
Sbjct: 695 WAILAILLGIALLFCILFTLVC-----GASGTSKQPKVIPDDLAQQNLIVSNTEAPGDD 748
Score = 33.9 bits (76), Expect = 0.70
Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 853 DSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLAD 899
D +L ++YEG GS AGS+ + E ++L++ P+F+ LA+
Sbjct: 852 DYVLTYNYEGRGSVAGSVGCCSERQE--EDGLEFLDNLEPKFRTLAE 896
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 412 bits (1059), Expect = e-115
Identities = 251/710 (35%), Positives = 378/710 (53%), Gaps = 33/710 (4%)
Query: 73 SSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLKPTLTEESV 132
SS+P DF+V DG VY R+ LS + F I+ DK Q + +V V L ++ V
Sbjct: 66 SSDP-DFRVLNDGSVYTARAVALSDKKRSFTIWLSDKRKQTQKEVTVLLE-----HQKKV 119
Query: 133 KESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLS 192
++ E V L+R KR W P ++ ENS GPFP L ++ SD +N +
Sbjct: 120 SKTRHTRETV-----------LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYT 168
Query: 193 LRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPID 252
+ YS++G G D+ P +F I +G L T+P+DRE+ F L A+A +G + P+
Sbjct: 169 VFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLP 228
Query: 253 IVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQA 312
+ I V D NDN P F ++N V E S+PGT V V A D D+P+ ++ L+Y I+ Q
Sbjct: 229 LPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQT 288
Query: 313 PSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITV 372
P SP +F+++ TG I TV+ LDRE V +Y+LI++ DM+G +GL T+T +ITV
Sbjct: 289 PR--SPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQ-FFGLIGTSTCIITV 345
Query: 373 TDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFA 432
TD NDN P F + V EN ++ + + + DKD +T W + I G+ G F
Sbjct: 346 TDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFK 405
Query: 433 IQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQH-PPQSTATVSVTVIDV 491
I TD +N+G+++VVKP+++E NR L + N+ P A+ I + A V+V V D+
Sbjct: 406 ISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDL 465
Query: 492 NENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNG 551
+E P P + +R +E L G+ + + A DP+ +RY KL DP W+ ID ++G
Sbjct: 466 DEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISG 525
Query: 552 QITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAE 611
I T +LDRE KN +YN T LA D S TGTL + + D+NDN P++L +
Sbjct: 526 SIITSKILDREVETPKNELYNITVLAIDK--DDRSCTGTLAVNIEDVNDNPPEILQEYVV 583
Query: 612 TCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFL 671
C+ P +I A+D D + PF F LP + I R W++T++N A+L+ +
Sbjct: 584 ICK-PKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQ---K 639
Query: 672 EAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLC 731
AG E I IT ++ +LRV +C+C C R G LG AI+AILL
Sbjct: 640 NAGFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLG 699
Query: 732 IIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEE 781
I +L ++L V + K ++ PED + N++ + E G++
Sbjct: 700 IALLFSVLLTLVCGVFGATKGKRF------PEDLAQQNLIISNTEAPGDD 743
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 397 bits (1020), Expect = e-110
Identities = 279/767 (36%), Positives = 407/767 (53%), Gaps = 54/767 (7%)
Query: 156 RQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFIINP 214
R KR WV + E GP PQ + ++ S+ DK + S++Y +TG GA IFII+
Sbjct: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGT----IFIIDD 105
Query: 215 ISGQLSVTKPLDREQIARFHLRAHAVDINGNQ-VENPIDIVINVIDMNDNRPEFLHQVWN 273
+G + TK LDREQ + L A A+D N+ +E + +I V D+NDN P+F +
Sbjct: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165
Query: 274 GTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDIIT 332
TVPE S GT V+ VTA DADDP N + Y I+ P F+++ +TG I T
Sbjct: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQP------YFSVDPKTGVIRT 219
Query: 333 VAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVP 392
+DRE + Y+++IQA DM G GLS + T IT+TDVNDNPP F + VP
Sbjct: 220 ALHNMDREAREHYSVVIQAKDMAGQ-VGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVP 278
Query: 393 EN-RVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPID 451
E+ +V V + D D + Y I GD G F+I TD + +G++++ KP++
Sbjct: 279 ESAQVGSAVGKIKANDADTGSNA--DMTYSIINGDGMGIFSISTDKETREGILSLKKPLN 336
Query: 452 FETNRMFVLTVAAENQVPLAKGIQH--PPQSTATVSVTVIDVNENPYFAPNPKIIRQEEG 509
+E + + L + N L H P + + + V DV+E P F+ ++ E
Sbjct: 337 YEKKKSYTLNIEGAN-THLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYEN 395
Query: 510 LHAGTMLTTFTAQDPDR---YMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNV 566
GT++ T AQDPD ++ I Y D + ID G I T VLDRE
Sbjct: 396 AKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDD--RFFNIDANTGTIRTTKVLDRE---- 449
Query: 567 KNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQ-EAETCETPDPNSI--NI 623
+ YN T AS+ P + T+ I +LD+NDN P++ + + CE P + I
Sbjct: 450 ETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTI 509
Query: 624 TALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQ-LNLKIKFLEA--GIYEVPI 680
+A D D N F F L + + N+T+ + A L + +F +Y +PI
Sbjct: 510 SATDKDDFANGPRFNFFLD-ERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPI 568
Query: 681 IITDSGNPPKSNISILRVKVCQCDSNG---DCTDVDRIVGAGLGTGAIIAILLCIIILLI 737
+I+D G P S+ S L ++VC C+ +G C + AGL TGA+IAILLC++ILL
Sbjct: 569 MISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLILLA 628
Query: 738 LVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPDTV 796
+V++F+ R K+ LI E+DVR+N++ YD+EGGGEED + +D++ L+ P
Sbjct: 629 IVVLFITL------RRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITALRNPSAA 682
Query: 797 EPDAIKPVGIRRMDERP-IHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSL 855
E R D RP + P++ S D+ +FI + L AD DP+ PPYDSL
Sbjct: 683 EELKY------RRDIRPEVKLTPRHQTSSTLESI-DVQEFIKQRLAEADLDPSVPPYDSL 735
Query: 856 LVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYG 902
+ YEG S AGS+SSL+S+++ +QDY YL DWGP FKKLA++YG
Sbjct: 736 QTYAYEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAELYG 782
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 393 bits (1009), Expect = e-109
Identities = 278/805 (34%), Positives = 426/805 (52%), Gaps = 55/805 (6%)
Query: 121 LSLKPTLTEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQEL 180
+ L T+ ++ E+E ++ + S QR KR WV + E G P +
Sbjct: 26 MDLTTTVLSDTPTPQGELEALLSDKPQSH-----QRTKRSWVWNQFFVLEEYTGTDPLYV 80
Query: 181 VRIRSDRDK-NLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHA 239
++ SD D+ + S++Y ++G GA +F I+ +G + + LDRE+ A++ LRA A
Sbjct: 81 GKLHSDMDRGDGSIKYILSGEGAGI----VFTIDDTTGDIHAIQRLDREERAQYTLRAQA 136
Query: 240 VDIN-GNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPN 298
+D G +E + +I + D+NDN P+FL + TVPE S GT V+ VTA DADDP
Sbjct: 137 LDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPT 196
Query: 299 ALNGM-LRYRIVSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGN 357
N + Y I+ P F+++++TG I T +DRE + Y +IIQA DM G
Sbjct: 197 YGNSARVVYSILQGQP------YFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDM-GG 249
Query: 358 PTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENR-VDIIVANLTVTDKDQPHTPAW 416
GL+ T T IT++DVNDNPP F + V E+ + V + D D+
Sbjct: 250 QLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEM 309
Query: 417 NAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQH 476
Y I GD F I TDPN G++TV KP+ FE+ + + L V N + +
Sbjct: 310 K--YTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNL 367
Query: 477 PP-QSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYT 535
P Q T TV ++V DV+E P F P + E + GT + +A+DPD +IRY+
Sbjct: 368 GPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPD-VTNNSIRYS 426
Query: 536 --KLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQI 593
+ SDP + +D G + T LDRE + + +N T LA + P G+ + I
Sbjct: 427 IDRSSDPGRFFYVDITTGALMTARPLDRE----EFSWHNITVLAMEMNNPSQVGSVPVTI 482
Query: 594 YLLDINDNAPQVLPQ--EAETCETPDPNSI--NITALDYDIDPNAGPFAFDLPLSPVTIK 649
+LD+NDNAP+ P+ EA CE + ++A+D D DP G F L+P
Sbjct: 483 KVLDVNDNAPE-FPRFYEAFVCENAKAGQLIQTVSAVDQD-DPRNGQH-FYYSLAPEAAN 539
Query: 650 R-NWTITRLNGDFAQLNLK---IKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDS 705
N+TI + A++ + + E ++ +PI+I DSG P S+ L ++VC CD
Sbjct: 540 NPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDD 599
Query: 706 NG---DCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDP 762
+G C+ ++ L GA+IAIL CI +LL+LVL+ ++ M+R K+ +ID
Sbjct: 600 DGHVMSCSPEAYMLPVSLSRGALIAILACIFVLLVLVLL-ILSMRRHRKQ----PYIIDD 654
Query: 763 EDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPDTVEPDAIKPVGIRRMDERP-IHAEPQY 820
E+++ +NI++YD+EGGGEED + +D++ + P + A R D P I + +Y
Sbjct: 655 EENIHENIVRYDDEGGGEEDTEAFDIAAMWNPREAQAGAAPKT---RQDMLPEIESLSRY 711
Query: 821 PVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGG 880
++ A + + ++ L AD D APP+DSL + +EG GS AGSLSSL S++S
Sbjct: 712 VPQTCAVN-STVHSYVLAKLYEADMDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSATSDS 770
Query: 881 EQDYDYLNDWGPRFKKLADMYGGGD 905
EQ +D+L DWGPRF+KLA++YG +
Sbjct: 771 EQSFDFLTDWGPRFRKLAELYGASE 795
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 376 bits (966), Expect = e-104
Identities = 277/767 (36%), Positives = 394/767 (51%), Gaps = 49/767 (6%)
Query: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLS-LRYSVTGPGADQPPTGIFII 212
L R +R WV + E GP P + ++ SD D+ +Y +TG GA +F+I
Sbjct: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VFVI 94
Query: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDINGNQ-VENPIDIVINVIDMNDNRPEFLHQV 271
+ +G + VTK LDRE+ A++ L A AVD N+ +E P + +I V D+NDN P F
Sbjct: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
Query: 272 WNGTVPEGSKPGTYVMTVTAIDADDPNALNGM-LRYRIVSQAPSTPSPNMFTINNETGDI 330
++ TVPE S GT V+ VTA DADDP+ N L Y ++ P F+++ +TG +
Sbjct: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTGVV 208
Query: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
T +DRE +++ ++IQA DM G+ GLS + T +T++DVNDNPP+F +
Sbjct: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMG-GLSGSTTVTVTLSDVNDNPPKFPQSLYQFS 267
Query: 391 VPENR-VDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKP 449
V E +V L D D Y I G+ + F+I TD DGL+TV KP
Sbjct: 268 VVETAGPGTLVGRLRAQDPDLGDNALM--AYSILDGEGSEAFSISTDLQGRDGLLTVRKP 325
Query: 450 IDFETNRMFVLTVAAENQVPLAKGIQHPP-QSTATVSVTVIDVNENPYFAPNPKIIRQEE 508
+DFE+ R + V A N + ++ P + A+V V V D E P F + E
Sbjct: 326 LDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPE 385
Query: 509 GLHAGTMLTTFTAQDPDRYMQQNIRYTKL--SDPANWLKIDPVNGQITTIAVLDRESPNV 566
GT++ +A D D IRY+ L SDP I P G I T A LDRE+
Sbjct: 386 NKAPGTLVGQISAADLDSPASP-IRYSILPHSDPERCFSIQPEEGTIHTAAPLDREA--- 441
Query: 567 KNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVL-PQEAETCETPDPNSIN--I 623
+N T LA++ + + I LD NDNAPQ+ P + C++ P + I
Sbjct: 442 -RAWHNLTVLATELDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVI 500
Query: 624 TALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFLEA--GIYEVPII 681
ALD D N+ +F PL P N+T+ A L L + Y VPI
Sbjct: 501 RALDRDEVGNSSHVSFQGPLGP---DANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIE 557
Query: 682 ITDSGNPPKSNISILRVKVCQCDSNGD---CTDVDRIVGAGLGTGAIIAILLCIIILLIL 738
+ D G P S+ + + V VC+C +G C + AGL TGA++AI+ C+ LL L
Sbjct: 558 LWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLAL 617
Query: 739 VLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPDTVE 797
V++FV RR K+ + L++ E+DVR+NI+ YD+EGGGEED + +D++ LQ PD
Sbjct: 618 VVLFVAL--RRQKQ---EALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAA 672
Query: 798 PDAIKPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLV 857
P A P R + R + P P P D+ + L+ AD DP PPYDS+ V
Sbjct: 673 PPAPGPPARRDVLPRARVSRQPRP-----PGPADVAQLLALRLREADEDPGVPPYDSVQV 727
Query: 858 FDYEGSGSTAGSLSSLNSSS--SGGEQDYDYLNDWGPRFKKLADMYG 902
+ YEG GS+ GSLSSL S S G + L+DWGP F+ LA++YG
Sbjct: 728 YGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYG 774
>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
Length = 819
Score = 364 bits (934), Expect = e-100
Identities = 283/801 (35%), Positives = 395/801 (49%), Gaps = 79/801 (9%)
Query: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLS-LRYSVTGPGADQPPTGIFII 212
L R +R WV + E GP P + ++ SD D+ +Y +TG GA +F+I
Sbjct: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VFVI 94
Query: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDINGNQ-VENPIDIVINVIDMNDNRPEFLHQV 271
+ +G + VTK LDRE+ A++ L A AVD N+ +E P + +I V D+NDN P F
Sbjct: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
Query: 272 WNGTVPEGSKPGTYVMTVTAIDADDPNALN-GMLRYRIVSQAPSTPSPNMFTINNETGDI 330
++ TVPE S GT V+ VTA DADDP+ N L Y ++ P F+++ +TG +
Sbjct: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTGVV 208
Query: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
T +DRE +++ ++IQA DM G+ GLS + T +T++DVNDNPP+F +
Sbjct: 209 RTAIPNMDRETQEEFLVVIQAKDMGGH-MGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFS 267
Query: 391 VPENR-VDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKP 449
V E +V L D D Y I G+ + F+I TD DGL+TV KP
Sbjct: 268 VVETAGPGTLVGRLRAQDPDLGDNAL--MAYSILDGEGSEAFSISTDLQGRDGLLTVRKP 325
Query: 450 IDFETNRMFVLTVAAENQVPLAKGIQHPP-QSTATVSVTVIDVNENPYFAPNPKIIRQEE 508
+DFE+ R + V A N + ++ P + A+V V V D E P F + E
Sbjct: 326 LDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPE 385
Query: 509 GLHAGTMLTTFTAQDPDRYMQQNIRYTKL--SDPANWLKIDPVNGQITTIAVLDRESPNV 566
GT++ +A D D IRY+ L SDP I P G I T A LDRE+
Sbjct: 386 NKAPGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAW 444
Query: 567 KNNIYNATFL------------------------------ASDNGIPPMSGTGT----LQ 592
N AT L S GIP S +
Sbjct: 445 HNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVA 504
Query: 593 IYLLDINDNAPQVL-PQEAETCETPDPNSI--NITALDYDIDPNAGPFAFDLPLSPVTIK 649
I LD NDNAPQ+ P + C++ P + I ALD D N+ +F PL P
Sbjct: 505 IQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGP---D 561
Query: 650 RNWTITRLNGDFAQLNLKIKFL--EAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNG 707
N+T+ A L L + Y VPI + D G P S+ + + V VC+C +G
Sbjct: 562 ANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDG 621
Query: 708 ---DCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPED 764
C + AGL TGA++AI+ C+ LL LV++FV RR K+ + L++ E+
Sbjct: 622 SVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVA--LRRQKQ---EALMVLEEE 676
Query: 765 DVRDNILKYDEEGGGEEDQD-YDLSQLQQPDTVEPDAIKPVGIRRMDERPIHAEPQYPVR 823
DVR+NI+ YD+EGGGEED + +D++ LQ PD P A P R D P + P
Sbjct: 677 DVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPA--RRDVLPRARVSRQP-- 732
Query: 824 SAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSS--SGGE 881
P P D+ + L+ AD DP PPYDS+ V+ YEG GS+ GSLSSL S S G
Sbjct: 733 -RPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAP 791
Query: 882 QDYDYLNDWGPRFKKLADMYG 902
+ L+DWGP F+ LA++YG
Sbjct: 792 GPAEPLDDWGPLFRTLAELYG 812
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 357 bits (915), Expect = 4e-98
Identities = 264/794 (33%), Positives = 401/794 (50%), Gaps = 72/794 (9%)
Query: 156 RQKRDWVIPPINLPENSRGPFPQELVRIRSDRDK-NLSLRYSVTGPGADQPPTGIFIINP 214
R KR WV + E G P + +I SD D+ + +++Y+++G GA IF+I+
Sbjct: 59 RVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGT----IFLIDE 114
Query: 215 ISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENP-IDIVINVIDMNDNRPEFLHQVWN 273
++G + + LDREQ + LRA A D N++ P + +I V D+ND+ P FLH +
Sbjct: 115 LTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYI 174
Query: 274 GTVPEGSKPGTYVMTVTAIDADDPN-ALNGMLRYRIVSQAPSTPSPNMFTINNETGDIIT 332
G+V E S GT VM V A DADDP + L Y ++ + FT++ +TG I T
Sbjct: 175 GSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLD------GEHHFTVDPKTGVIRT 228
Query: 333 VAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVP 392
LDRE ++Y ++IQATDM G GLS + T I VTDVNDNPP F + +
Sbjct: 229 AVPDLDRESQERYEVVIQATDMAGQ-LGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQ 287
Query: 393 ENR-VDIIVANLTVTDKDQPHTPAWNAVYRI-----SGGDPTGRFAIQTDPNSNDGLVTV 446
E+ + V + D D + Y + SGGD F + TD ++ + ++ V
Sbjct: 288 ESAPIGTAVGRVKAEDSDVGENT--DMTYHLKDESSSGGDV---FKVTTDSDTQEAIIVV 342
Query: 447 VKPIDFETNRMFVLTVAAENQVPLAKGIQHPP-QSTATVSVTVIDVNENPYFAPNPKIIR 505
K +DFE+ + + + A N+ + + A V V V DV+E P F P ++
Sbjct: 343 QKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLE 402
Query: 506 QEEGLHAGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRES 563
+E G+++ TA+DPD + +RY + SD ID G I T LDRE+
Sbjct: 403 VQEDAQVGSLVGVVTARDPDA-ANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRET 461
Query: 564 PNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVL-PQEAETCETPDPNSIN 622
+N T LA + +L+I +LD+NDN P++ P EA CE P +
Sbjct: 462 AGW----HNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLI 517
Query: 623 ITALDYDIDPNAGPFAFDLPLSPVTIKR-NWTITRLNGDFAQLNLK---IKFLEAGIYEV 678
T D D G F L P ++++ + + A ++ + E ++ +
Sbjct: 518 QTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFL 577
Query: 679 PIIITDSGNPPKSNISILRVKVCQCDSNG---DCTDVDRIVGAGLGTGAIIAILLCIIIL 735
PI++ DSG P S+ L +++C CDS+G C ++ A L GA+IA+L+C++IL
Sbjct: 578 PILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLIL 637
Query: 736 LILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQD----------Y 785
++LVL+ ++ ++R K L D ++D+RDN++KY++EGGGE+D + Y
Sbjct: 638 VVLVLL-ILTLRRHHKSH----LSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLY 692
Query: 786 DLSQLQQPDTVEP-----------DAIKPVGIRRMDERPIHAEPQYPVRSAAPHPGDIGD 834
D +L+ D A P ER H+ PQ P S P D
Sbjct: 693 DFGELKGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSER--HSLPQGPP-SPEPDFSVFRD 749
Query: 835 FINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRF 894
FI+ + AD D + PPYD+ + +EG+ S A SLSSL+S SSG EQD+ YL+ WGPRF
Sbjct: 750 FISRKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRF 809
Query: 895 KKLADMYGG--GDD 906
+ LA +Y G GDD
Sbjct: 810 RPLAALYAGHRGDD 823
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 357 bits (915), Expect = 4e-98
Identities = 250/799 (31%), Positives = 393/799 (49%), Gaps = 73/799 (9%)
Query: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQ-PPTGIFII 212
L+R KR WVI + L E GPFP+ + + ++ N+SL Y ++GPG D+ P G+F +
Sbjct: 49 LRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSL 108
Query: 213 NPI-SGQLSVTKPLDREQIARFHLRAHAVDIN-GNQVENPIDIVINVIDMNDNRPEFLHQ 270
+G++ V +P+DRE F + V+ + G V+ + I + D+ND+ P+F +
Sbjct: 109 EDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEK 168
Query: 271 VWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQAPSTPSPNMFTINNETGDI 330
+N TV E G + + A+D D+ N N + Y ++SQ P F ++ +G+I
Sbjct: 169 EFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESG-FRVDRLSGEI 227
Query: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
++ LD E Q+TL+I+A D G P+ LS+T T + V + N++ P FT + +
Sbjct: 228 -RLSGCLDYETAPQFTLLIRARDC-GEPS--LSSTTTVHVDVQEGNNHRPAFTQENYKVQ 283
Query: 391 VPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPI 450
+PE R V L V D+D P T AW A + I G+ G F I TDP +N+G++ V+KP+
Sbjct: 284 IPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPL 343
Query: 451 DFETNRMFVLTVAAENQVPLA---KGIQHPPQ---STATVSVTVIDVNENPYFAPNPKII 504
D+ET L + EN+ L +G PP+ ++ATVSV V D N+ P F P I+
Sbjct: 344 DYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIV 403
Query: 505 RQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESP 564
+EEG GT+L TF A DPD IRY + DPANW+ +D +G + T+ +DRESP
Sbjct: 404 NKEEGARPGTLLGTFNAMDPD----SQIRYELVHDPANWVSVDKNSGVVITVEPIDRESP 459
Query: 565 NVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQE--AETCETPDPNSIN 622
+V N+ Y A D+G PP + TGTL ++L DINDN P + P+ E CE+ ++
Sbjct: 460 HVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLH 519
Query: 623 ITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFLEAGIYEVPIII 682
I A D D++P + PF F+L + + W + R G +L L ++ L G Y VP+ I
Sbjct: 520 IEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVEL-LTLRSLPRGNYLVPLFI 578
Query: 683 TDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMF 742
D S + V++C C S C ++ GL GA+ + + L + +L
Sbjct: 579 GDKQG--LSQKQTVHVRICPCASGLTCVEL-ADAEVGLHVGALFPVCAAFVALAVALLFL 635
Query: 743 VVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTV--EPDA 800
+ + +R + D+ ++ Y+ E G Q + + Q+P + A
Sbjct: 636 LRCYFVLEPKRHGCSV---SNDEGHQTLVMYNAESKGTSAQTWSDVEGQRPALLICTAAA 692
Query: 801 IKPVGIRRMDERP------------------------------IHAEPQYPVRS-----A 825
G++ ++E P IH+ P YP +
Sbjct: 693 GPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSVKNIHSTPAYPDATMHRQLL 752
Query: 826 APHPGDIGDFINEGLKAA---DNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQ 882
AP G + + +N+ L A ++DP P+ V+ EG A SLSSL S E
Sbjct: 753 APVEGRMAETLNQKLHVANVLEDDPGYLPH----VYSEEGECGGAPSLSSLASLEQ--EL 806
Query: 883 DYDYLNDWGPRFKKLADMY 901
D L+ G + ++Y
Sbjct: 807 QPDLLDSLGSKATPFEEIY 825
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 354 bits (908), Expect = 2e-97
Identities = 256/765 (33%), Positives = 400/765 (52%), Gaps = 49/765 (6%)
Query: 155 QRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINP 214
+RQKRDW+ +++ E P + +I+S + + +Y + G + +F ++
Sbjct: 43 RRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVSRK-NAKYLLKGEYVGK----VFRVDA 97
Query: 215 ISGQLSVTKPLDREQIARFHLRAHAVDIN-GNQVENPIDIVINVIDMNDNRPEFLHQVWN 273
+G + + LDRE I+ +HL A VD + G +E P I V D+NDN P F H+++N
Sbjct: 98 ETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRLFN 157
Query: 274 GTVPEGSKPGTYVMTVTAIDADDPNALN-GMLRYRIVSQAPSTPSPNMFTINNETGDIIT 332
+VPE S GT V++VTA+DADDP + + Y+I+ F I+N +G IIT
Sbjct: 158 ASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILK------GKEYFAIDN-SGRIIT 210
Query: 333 VAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVP 392
+ LDREK +Y ++++A D +G G S TAT ++T+ D+NDN P FT + VP
Sbjct: 211 ITKSLDREKQARYEIVVEARDAQG--LRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVP 268
Query: 393 EN-RVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPID 451
E+ RV V +L V D D+P Y I GD F I+T+P N+G++ +KP+D
Sbjct: 269 EDTRVGTSVGSLFVEDPDEPQNRMTK--YSILRGDYQDAFTIETNPAHNEGIIKPMKPLD 326
Query: 452 FETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLH 511
+E + + V A + + + P + A V + + DV+E P F P Q +
Sbjct: 327 YEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDVDEPPIFQ-QPFYHFQLKENQ 385
Query: 512 AGTMLTTFTAQDPDRYMQQNIRYT--KLSDPANWLKIDPVNGQITTIAVLDRESPNVKNN 569
++ T A DPD + +I Y+ + SD + ++ G I LDRE N
Sbjct: 386 KKPLIGTVLAMDPDA-ARHSIGYSIRRTSDKGQFFRVTK-KGDIYNEKELDREVYPWYNL 443
Query: 570 IYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVL-PQEAETCETPDPNSI--NITAL 626
A L S + I +LD NDNAP+ P + + CE + I+A+
Sbjct: 444 TVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAVHGQLVLQISAI 503
Query: 627 DYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFLE---AGIYEVPIIIT 683
D DI P F F L + N+T+T + + A + +K + ++ +P++I+
Sbjct: 504 DKDITPRNVKFKFIL-----NTENNFTLTDNHDNTANITVKYGQFDREHTKVHFLPVVIS 558
Query: 684 DSGNPPKSNISILRVKVCQCDSNGDCTDV-DRIVGAGLGTGAIIAILLCIIILLILVLMF 742
D+G P ++ S L V VC+C+ G+ T D G+ A++AILLCI+ + ++ L+
Sbjct: 559 DNGMPSRTGTSTLTVAVCKCNEQGEFTFCEDMAAQVGVSIQAVVAILLCILTITVITLL- 617
Query: 743 VVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQ-DYDLSQLQQPDTVEPDAI 801
++++RR +++ PE + + ++ YDEEGGGE D YD+S L ++V
Sbjct: 618 -IFLRRRLRKQARAHGKSVPE--IHEQLVTYDEEGGGEMDTTSYDVSVL---NSVRRGGA 671
Query: 802 KPVGIRRMDERP-IHAEPQYPVRSA-APH--PGDIGDFINEGLKAADNDPTAPPYDSLLV 857
KP +D RP ++A+ Q P R A H PG++ I AD+D PPYD+L +
Sbjct: 672 KPPR-PALDARPSLYAQVQKPPRHAPGAHGGPGEMAAMIEVKKDEADHDGDGPPYDTLHI 730
Query: 858 FDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYG 902
+ YEGS S A SLSSL + SS + DYD+LNDWGPRFK LA++YG
Sbjct: 731 YGYEGSESIAESLSSLGTDSSDSDVDYDFLNDWGPRFKMLAELYG 775
>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
Length = 1118
Score = 336 bits (862), Expect = 5e-92
Identities = 204/598 (34%), Positives = 304/598 (50%), Gaps = 12/598 (2%)
Query: 153 HLQRQKRDWVIPPINLPENSRGPFPQELVRIRSD--RDKNLSLRYSVTGPGADQPPTGIF 210
HL RQKR W+ P+ L E + +I SD ++ L + Y TG G +PP GIF
Sbjct: 43 HLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIF 102
Query: 211 IINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQ 270
+ N +G+L+VT LDRE+ F L +A+D GN VE P+++ I V+D+NDN P F
Sbjct: 103 VFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQD 162
Query: 271 VWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQAPSTPSPNMFTINNETGDI 330
V+ G+V E S T VM + A DAD+PN LN + YRIVS P+ P +F +N +TG+I
Sbjct: 163 VFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPP--VFYLNKDTGEI 220
Query: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
T + LDRE+ YTL ++A D G T A I + DVNDN P G
Sbjct: 221 YTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGM 280
Query: 391 VPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPI 450
V EN+V++ V + V D D+ + W A + + G+ G F I+TD +N+G+VT++K +
Sbjct: 281 VEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEV 340
Query: 451 DFETNRMFVLTVAAENQVPLAKGIQHPPQST-ATVSVTVIDVNENPYFAPNPKIIRQEEG 509
D+E + +V N+ K I+ + T + V V +V E +F + I E
Sbjct: 341 DYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSES 400
Query: 510 L---HAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNV 566
+ G ++ F A D D + + RY KL D NW+ +D V +I + D ES V
Sbjct: 401 MDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYV 460
Query: 567 KNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETCETPDPNSINITAL 626
+N Y +A P + TGT+ I + DINDN P ++ C D +N+TA
Sbjct: 461 QNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICH--DAEYVNVTAE 518
Query: 627 DYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFLEAGIYEVPIIITDSG 686
D D PN+GPF+F + P + W I R L K L G E+ +I+D+
Sbjct: 519 DLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKL--GRSEIQFLISDNQ 576
Query: 687 NPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVV 744
+L + VC+C C + GLG AI ++L ++LL++ L+ ++
Sbjct: 577 GFSCPEKQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLM 634
>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
Length = 1040
Score = 317 bits (811), Expect = 4e-86
Identities = 242/844 (28%), Positives = 376/844 (44%), Gaps = 103/844 (12%)
Query: 139 EEIVFPRQFSKHSGH-----LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSL 193
E IV ++F +G ++RQKR+W+ E + +IRSD + N +
Sbjct: 24 EFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKI 83
Query: 194 RYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPIDI 253
Y ++G G D+PP G+F INP +G++++T +DRE F + A++ G +E P+++
Sbjct: 84 TYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLEL 143
Query: 254 VINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQAP 313
+ V+D+NDN P F V+ ++ E S T V+ + A DAD+ N LN + Y+IVSQ P
Sbjct: 144 RVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEP 203
Query: 314 STPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVT 373
S MF +N TG++ T+++ LDRE+ Y L+++ +D +G GLS+ I V
Sbjct: 204 S--GAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDG-AADGLSSECDCRIKVL 260
Query: 374 DVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAI 433
DVNDN P ++ + EN + + L D D+ T W A Y I G+ F I
Sbjct: 261 DVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDI 320
Query: 434 QTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTAT-VSVTVIDVN 492
QTDP +N+G++ VVK +D+E L++ +NQ + Q T V + V+DV
Sbjct: 321 QTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVR 380
Query: 493 ENPYFAPNPKIIRQEEGLHAGTMLT----TFTAQDPDR-YMQQNIRYTKLSDPANWLKID 547
E P F P+ EG+ ++L T+TA D D ++RY D +WLKID
Sbjct: 381 EGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKID 440
Query: 548 PVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLP 607
G+I D++S + N IY A LA D+G + TGT+ I + DIND P + P
Sbjct: 441 SRTGEIQFSREFDKKSKYIINGIYTAEILAIDDG-SGKTATGTICIEVPDINDYCPNIFP 499
Query: 608 QEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLK 667
+ C I++ Y PF F + P I W + N A L K
Sbjct: 500 ERRTICIDSPSVLISVNEHSY-----GSPFTFCVVDEPPGIADMWDVRSTNATSAILTAK 554
Query: 668 IKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTD-------VDRIVG--- 717
+ L G YE+PI++ DS N ++++ C CD N C D + I G
Sbjct: 555 -QVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTY 613
Query: 718 ------------AGLGTGAIIAILLCIIILLIL-VLMFVVWMKRRDKERQAKQLLIDPED 764
GLG I ++L I++L++ +L+ + K+R E + PE
Sbjct: 614 GPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEG 673
Query: 765 DVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRMDERPIH--------- 815
+ + EG ED+ D+S + P T RMD I+
Sbjct: 674 G-EGVMQSWRIEGAHPEDR--DVSNICAPMTASNTQ------DRMDSSEIYTNTYAAGGT 724
Query: 816 -------------------------AEPQYPVRSAAPHPGDIGDFINEGLKA-------- 842
A R + G + D+ + +
Sbjct: 725 VEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFS 784
Query: 843 ------ADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKK 896
AD D P D LL++D+EG GS GS+ S + D + P+F+
Sbjct: 785 EKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGC--CSWIVDDLDESCMETLDPKFRT 842
Query: 897 LADM 900
LA++
Sbjct: 843 LAEI 846
>gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]
Length = 1059
Score = 309 bits (791), Expect = 9e-84
Identities = 206/659 (31%), Positives = 319/659 (48%), Gaps = 44/659 (6%)
Query: 139 EEIVFPRQFSKHSGH-----LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSL 193
E IV ++F +G ++RQKR+W+ E + +IRSD + N +
Sbjct: 24 EFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKI 83
Query: 194 RYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPIDI 253
Y ++G G D+PP G+F INP +G++++T +DRE F + A++ G +E P+++
Sbjct: 84 TYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLEL 143
Query: 254 VINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQAP 313
+ V+D+NDN P F V+ ++ E S T V+ + A DAD+ N LN + Y+IVSQ P
Sbjct: 144 RVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEP 203
Query: 314 STPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVT 373
S MF +N TG++ T+++ LDRE+ Y L+++ +D +G GLS+ I V
Sbjct: 204 S--GAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDG-AADGLSSECDCRIKVL 260
Query: 374 DVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAI 433
DVNDN P ++ + EN + + L D D+ T W A Y I G+ F I
Sbjct: 261 DVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDI 320
Query: 434 QTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTAT-VSVTVIDVN 492
QTDP +N+G++ VVK +D+E L++ +NQ + Q T V + V+DV
Sbjct: 321 QTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVR 380
Query: 493 ENPYFAPNPKIIRQEEGLHAGTMLT----TFTAQDPDR-YMQQNIRYTKLSDPANWLKID 547
E P F P+ EG+ ++L T+TA D D ++RY D +WLKID
Sbjct: 381 EGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKID 440
Query: 548 PVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLP 607
G+I D++S + N IY A LA D+G + TGT+ I + DIND P + P
Sbjct: 441 SRTGEIQFSREFDKKSKYIINGIYTAEILAIDDG-SGKTATGTICIEVPDINDYCPNIFP 499
Query: 608 QEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLK 667
+ C I++ Y PF F + P I W + N A L K
Sbjct: 500 ERRTICIDSPSVLISVNEHSY-----GSPFTFCVVDEPPGIADMWDVRSTNATSAILTAK 554
Query: 668 IKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTD-------VDRIVG--- 717
+ L G YE+PI++ DS N ++++ C CD N C D + I G
Sbjct: 555 -QVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTY 613
Query: 718 ------------AGLGTGAIIAILLCIIILLIL-VLMFVVWMKRRDKERQAKQLLIDPE 763
GLG I ++L I++L++ +L+ + K+R E + PE
Sbjct: 614 GPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPE 672
Score = 35.8 bits (81), Expect = 0.19
Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 835 FINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRF 894
F + AD D P D LL++D+EG GS GS+ S + D + P+F
Sbjct: 802 FSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGC--CSWIVDDLDESCMETLDPKF 859
Query: 895 KKLADM 900
+ LA++
Sbjct: 860 RTLAEI 865
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,471,525
Number of Sequences: 37866
Number of extensions: 1850894
Number of successful extensions: 9693
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 4792
Number of HSP's gapped (non-prelim): 1069
length of query: 906
length of database: 18,247,518
effective HSP length: 111
effective length of query: 795
effective length of database: 14,044,392
effective search space: 11165291640
effective search space used: 11165291640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.