Guide to the Human Genome
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Name: HSD17B11 Sequence: fasta or formatted (300aa) NCBI GI: 142976729
Description:

estradiol 17-beta-dehydrogenase 11

Referenced in:

Alcohol and Aldehyde Dehydrogenases
Steroid Hormones

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.3         25           2
 C cysteine            2.0          6           1
 D aspartate           3.0          9           1
 E glutamate           5.3         16           2
 F phenylalanine       6.0         18           1
 G glycine             6.0         18           1
 H histidine           3.0          9           1
 I isoleucine          7.0         21           1
 K lysine              9.0         27           2
 L leucine            12.0         36           4
 M methionine          1.7          5           1
 N asparagine          3.7         11           2
 P proline             3.7         11           1
 Q glutamine           2.0          6           1
 R arginine            2.3          7           2
 S serine              6.0         18           2
 T threonine           7.7         23           2
 V valine              9.0         27           2
 W tryptophan          0.7          2           1
 Y tyrosine            1.7          5           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   estradiol 17-beta-dehydrogenase 11 
HSD17B13              0.645   hydroxysteroid (17-beta) dehydrogenase 13 isoform A...
HSD17B13              0.532   hydroxysteroid (17-beta) dehydrogenase 13 isoform B...
SDR16C5               0.376   epidermal retinal dehydrogenase 2 
SDR16C6               0.336   short chain dehydrogenase/reductase family 16C, mem...
RDH10                 0.330   retinol dehydrogenase 10 
DHRS3                 0.269   dehydrogenase/reductase (SDR family) member 3 
DHRS7                 0.133   dehydrogenase/reductase (SDR family) member 7 
DHRS7B                0.133   dehydrogenase/reductase (SDR family) member 7B [Homo...
HSD11B1               0.118   11-beta-hydroxysteroid dehydrogenase 1 
HSD11B1               0.118   11-beta-hydroxysteroid dehydrogenase 1 
DHRS11                0.113   short-chain dehydrogenase/reductase 
HPGD                  0.110   hydroxyprostaglandin dehydrogenase 15-(NAD) isoform ...
BDH2                  0.101   3-hydroxybutyrate dehydrogenase, type 2 
HSD17B12              0.095   hydroxysteroid (17-beta) dehydrogenase 12 
DHRS4                 0.094   peroxisomal short-chain alcohol dehydrogenase 
HSD17B1               0.092   hydroxysteroid (17-beta) dehydrogenase 1 
RDH13                 0.090   retinol dehydrogenase 13 isoform 1 
DHRS7C                0.088   dehydrogenase/reductase (SDR family) member 7C [Hom...
HSD11B1L              0.088   short-chain dehydrogenase/reductase 10 isoform b [Ho...
RDH12                 0.087   retinol dehydrogenase 12 
HSD11B1L              0.087   short-chain dehydrogenase/reductase 10 isoform e [Ho...
DHRS4L2               0.085   dehydrogenase/reductase (SDR family) member 4 like ...
RDH11                 0.085   retinol dehydrogenase 11 
CBR4                  0.080   carbonic reductase 4 
HSDL1                 0.080   hydroxysteroid dehydrogenase like 1 isoform a [Homo...
RDH8                  0.080   retinol dehydrogenase 8 (all-trans) 
HPGD                  0.078   hydroxyprostaglandin dehydrogenase 15-(NAD) isoform...
HSD17B3               0.078   estradiol 17 beta-dehydrogenase 3 
DHRS2                 0.078   dehydrogenase/reductase member 2 isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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