Guide to the Human Genome
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Name: HSD17B12 Sequence: fasta or formatted (312aa) NCBI GI: 7705855
Description:

hydroxysteroid (17-beta) dehydrogenase 12

Referenced in:

Alcohol and Aldehyde Dehydrogenases
Fatty Acid Synthesis
Steroid Hormones

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.7         21           2
 C cysteine            0.6          2           1
 D aspartate           3.5         11           1
 E glutamate           5.1         16           2
 F phenylalanine       3.5         11           2
 G glycine             8.0         25           1
 H histidine           1.3          4           1
 I isoleucine          7.4         23           2
 K lysine              9.0         28           2
 L leucine            10.3         32           2
 M methionine          3.2         10           1
 N asparagine          3.8         12           2
 P proline             3.8         12           1
 Q glutamine           1.6          5           1
 R arginine            2.9          9           1
 S serine              8.7         27           2
 T threonine           5.8         18           1
 V valine              9.0         28           2
 W tryptophan          1.3          4           1
 Y tyrosine            4.5         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hydroxysteroid (17-beta) dehydrogenase 12 
HSDL1                 0.341   hydroxysteroid dehydrogenase like 1 isoform a [Homo...
HSD17B3               0.319   estradiol 17 beta-dehydrogenase 3 
HSDL1                 0.199   hydroxysteroid dehydrogenase like 1 isoform b [Homo...
DHRS7B                0.095   dehydrogenase/reductase (SDR family) member 7B [Homo...
HSD17B11              0.092   estradiol 17-beta-dehydrogenase 11 
DHRS7                 0.092   dehydrogenase/reductase (SDR family) member 7 
HSD11B1               0.083   11-beta-hydroxysteroid dehydrogenase 1 
HSD11B1               0.083   11-beta-hydroxysteroid dehydrogenase 1 
DHRS4                 0.081   peroxisomal short-chain alcohol dehydrogenase 
DHRS11                0.076   short-chain dehydrogenase/reductase 
HPGD                  0.076   hydroxyprostaglandin dehydrogenase 15-(NAD) isoform ...
BDH1                  0.076   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
BDH1                  0.076   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
BDH1                  0.076   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
KDSR                  0.075   3-ketodihydrosphingosine reductase precursor 
HSD17B13              0.075   hydroxysteroid (17-beta) dehydrogenase 13 isoform A...
DHRS2                 0.070   dehydrogenase/reductase member 2 isoform 2 
DHRS2                 0.070   dehydrogenase/reductase member 2 isoform 1 
RDH8                  0.068   retinol dehydrogenase 8 (all-trans) 
SDR16C5               0.066   epidermal retinal dehydrogenase 2 
HPGD                  0.066   hydroxyprostaglandin dehydrogenase 15-(NAD) isoform...
DCXR                  0.065   dicarbonyl/L-xylulose reductase 
DHRS3                 0.063   dehydrogenase/reductase (SDR family) member 3 
DHRS4L2               0.063   dehydrogenase/reductase (SDR family) member 4 like ...
DHRS7C                0.061   dehydrogenase/reductase (SDR family) member 7C [Hom...
RDH16                 0.058   retinol dehydrogenase 16 
HSD17B2               0.054   hydroxysteroid (17-beta) dehydrogenase 2 
SDR9C7                0.054   short chain dehydrogenase/reductase family 9C, membe...
HSD17B6               0.053   hydroxysteroid (17-beta) dehydrogenase 6 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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