Guide to the Human Genome
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Name: HSD17B1 Sequence: fasta or formatted (328aa) NCBI GI: 223718074
Description:

hydroxysteroid (17-beta) dehydrogenase 1

Referenced in:

Alcohol and Aldehyde Dehydrogenases
Steroid Hormones

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.6         38           3
 C cysteine            1.8          6           1
 D aspartate           5.2         17           2
 E glutamate           7.0         23           2
 F phenylalanine       4.0         13           1
 G glycine            10.1         33           3
 H histidine           2.1          7           1
 I isoleucine          1.2          4           1
 K lysine              2.7          9           1
 L leucine            12.8         42           3
 M methionine          2.1          7           1
 N asparagine          1.5          5           1
 P proline             6.1         20           2
 Q glutamine           2.4          8           1
 R arginine            7.0         23           2
 S serine              5.5         18           2
 T threonine           4.9         16           2
 V valine              9.8         32           2
 W tryptophan          0.3          1           1
 Y tyrosine            1.8          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hydroxysteroid (17-beta) dehydrogenase 1 
RDH8                  0.310   retinol dehydrogenase 8 (all-trans) 
RDH16                 0.102   retinol dehydrogenase 16 
BDH1                  0.099   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
BDH1                  0.099   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
BDH1                  0.099   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
SDR9C7                0.094   short chain dehydrogenase/reductase family 9C, membe...
DHRS7                 0.090   dehydrogenase/reductase (SDR family) member 7 
DHRS7B                0.088   dehydrogenase/reductase (SDR family) member 7B [Homo...
HSD11B2               0.083   hydroxysteroid (11-beta) dehydrogenase 2 
HSD17B11              0.083   estradiol 17-beta-dehydrogenase 11 
RDH5                  0.080   retinol dehydrogenase 5 (11-cis and 9-cis) 
DHRS4                 0.078   peroxisomal short-chain alcohol dehydrogenase 
HSD17B6               0.070   hydroxysteroid (17-beta) dehydrogenase 6 
DHRS7C                0.069   dehydrogenase/reductase (SDR family) member 7C [Hom...
DHRS2                 0.069   dehydrogenase/reductase member 2 isoform 1 
DHRS2                 0.067   dehydrogenase/reductase member 2 isoform 2 
DHRS9                 0.067   NADP-dependent retinol dehydrogenase/reductase [Homo...
DHRS9                 0.067   NADP-dependent retinol dehydrogenase/reductase [Hom...
DHRS9                 0.067   NADP-dependent retinol dehydrogenase/reductase [Hom...
DHRS9                 0.067   NADP-dependent retinol dehydrogenase/reductase [Homo...
DHRS4L2               0.067   dehydrogenase/reductase (SDR family) member 4 like ...
KDSR                  0.064   3-ketodihydrosphingosine reductase precursor 
HSD17B13              0.058   hydroxysteroid (17-beta) dehydrogenase 13 isoform A...
HPGD                  0.056   hydroxyprostaglandin dehydrogenase 15-(NAD) isoform ...
SDR16C5               0.053   epidermal retinal dehydrogenase 2 
DHRS4L1               0.051   dehydrogenase/reductase (SDR family) member 4 like ...
RDH10                 0.050   retinol dehydrogenase 10 
DECR2                 0.050   2,4-dienoyl CoA reductase 2 
HSD17B13              0.048   hydroxysteroid (17-beta) dehydrogenase 13 isoform B...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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