Guide to the Human Genome
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Name: RDH8 Sequence: fasta or formatted (311aa) NCBI GI: 7657478
Description:

retinol dehydrogenase 8 (all-trans)

Referenced in:

Alcohol and Aldehyde Dehydrogenases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.0         25           3
 C cysteine            2.9          9           1
 D aspartate           3.5         11           1
 E glutamate           4.5         14           1
 F phenylalanine       4.5         14           2
 G glycine             7.7         24           1
 H histidine           1.3          4           1
 I isoleucine          3.9         12           1
 K lysine              3.2         10           2
 L leucine            13.2         41           2
 M methionine          2.3          7           1
 N asparagine          3.2         10           2
 P proline             5.1         16           2
 Q glutamine           5.5         17           1
 R arginine            6.4         20           3
 S serine              7.1         22           2
 T threonine           5.5         17           2
 V valine             10.3         32           2
 W tryptophan          0.0          0           0
 Y tyrosine            1.9          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   retinol dehydrogenase 8 (all-trans) 
HSD17B1               0.332   hydroxysteroid (17-beta) dehydrogenase 1 
DHRS7B                0.133   dehydrogenase/reductase (SDR family) member 7B [Homo...
DHRS7                 0.121   dehydrogenase/reductase (SDR family) member 7 
DHRS7C                0.116   dehydrogenase/reductase (SDR family) member 7C [Hom...
BDH1                  0.116   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
BDH1                  0.116   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
BDH1                  0.116   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
RDH5                  0.104   retinol dehydrogenase 5 (11-cis and 9-cis) 
SDR9C7                0.103   short chain dehydrogenase/reductase family 9C, membe...
KDSR                  0.101   3-ketodihydrosphingosine reductase precursor 
HSD17B13              0.096   hydroxysteroid (17-beta) dehydrogenase 13 isoform A...
DHRS9                 0.094   NADP-dependent retinol dehydrogenase/reductase [Homo...
DHRS9                 0.094   NADP-dependent retinol dehydrogenase/reductase [Hom...
DHRS9                 0.094   NADP-dependent retinol dehydrogenase/reductase [Hom...
DHRS9                 0.094   NADP-dependent retinol dehydrogenase/reductase [Homo...
RDH16                 0.092   retinol dehydrogenase 16 
DHRS4                 0.089   peroxisomal short-chain alcohol dehydrogenase 
DHRS2                 0.087   dehydrogenase/reductase member 2 isoform 2 
DHRS2                 0.087   dehydrogenase/reductase member 2 isoform 1 
HSD11B2               0.085   hydroxysteroid (11-beta) dehydrogenase 2 
CBR4                  0.085   carbonic reductase 4 
SDR16C5               0.084   epidermal retinal dehydrogenase 2 
HSD17B6               0.080   hydroxysteroid (17-beta) dehydrogenase 6 
HSD17B11              0.077   estradiol 17-beta-dehydrogenase 11 
DHRS11                0.077   short-chain dehydrogenase/reductase 
DHRS4L2               0.077   dehydrogenase/reductase (SDR family) member 4 like ...
HSD11B1               0.068   11-beta-hydroxysteroid dehydrogenase 1 
HSD11B1               0.068   11-beta-hydroxysteroid dehydrogenase 1 
HSD17B12              0.068   hydroxysteroid (17-beta) dehydrogenase 12 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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