Guide to the Human Genome
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Name: HSD11B1 Sequence: fasta or formatted (292aa) NCBI GI: 5031765
Description:

11-beta-hydroxysteroid dehydrogenase 1

Referenced in:

Alcohol and Aldehyde Dehydrogenases
Steroid Hormones

Other entries for this name:
alt mRNA [292aa] 11-beta-hydroxysteroid dehydrogenase 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.9         29           2
 C cysteine            1.4          4           1
 D aspartate           2.7          8           2
 E glutamate           5.8         17           2
 F phenylalanine       4.1         12           2
 G glycine             6.2         18           2
 H histidine           3.1          9           2
 I isoleucine          5.8         17           2
 K lysine              6.5         19           2
 L leucine            10.6         31           2
 M methionine          5.5         16           1
 N asparagine          3.4         10           1
 P proline             2.1          6           1
 Q glutamine           2.4          7           1
 R arginine            3.4         10           1
 S serine              8.2         24           2
 T threonine           4.8         14           2
 V valine              8.6         25           3
 W tryptophan          0.3          1           1
 Y tyrosine            5.1         15           4
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   11-beta-hydroxysteroid dehydrogenase 1 
HSD11B1               1.000   11-beta-hydroxysteroid dehydrogenase 1 
HSD11B1L              0.356   short-chain dehydrogenase/reductase 10 isoform b [Ho...
HSD11B1L              0.309   short-chain dehydrogenase/reductase 10 isoform e [Ho...
HSD11B1L              0.210   short-chain dehydrogenase/reductase 10 isoform c [Ho...
HSD11B1L              0.208   short-chain dehydrogenase/reductase 10 isoform a [Ho...
HSD11B1L              0.186   short-chain dehydrogenase/reductase 10 isoform d [Ho...
HSD11B1L              0.137   short-chain dehydrogenase/reductase 10 isoform f [Ho...
DHRS7                 0.130   dehydrogenase/reductase (SDR family) member 7 
HSD17B11              0.122   estradiol 17-beta-dehydrogenase 11 
DHRS7B                0.112   dehydrogenase/reductase (SDR family) member 7B [Homo...
DHRS4                 0.108   peroxisomal short-chain alcohol dehydrogenase 
HSD17B13              0.101   hydroxysteroid (17-beta) dehydrogenase 13 isoform A...
DHRS4L2               0.101   dehydrogenase/reductase (SDR family) member 4 like ...
KDSR                  0.093   3-ketodihydrosphingosine reductase precursor 
DHRS7C                0.091   dehydrogenase/reductase (SDR family) member 7C [Hom...
DHRS2                 0.091   dehydrogenase/reductase member 2 isoform 1 
DHRS2                 0.090   dehydrogenase/reductase member 2 isoform 2 
HSD17B12              0.090   hydroxysteroid (17-beta) dehydrogenase 12 
SDR16C5               0.082   epidermal retinal dehydrogenase 2 
SDR16C6               0.077   short chain dehydrogenase/reductase family 16C, mem...
DHRS4L1               0.075   dehydrogenase/reductase (SDR family) member 4 like ...
HSD17B6               0.075   hydroxysteroid (17-beta) dehydrogenase 6 
RDH8                  0.073   retinol dehydrogenase 8 (all-trans) 
RDH5                  0.073   retinol dehydrogenase 5 (11-cis and 9-cis) 
DHRS3                 0.069   dehydrogenase/reductase (SDR family) member 3 
DHRS1                 0.069   dehydrogenase/reductase (SDR family) member 1 [Homo...
DHRS1                 0.069   dehydrogenase/reductase (SDR family) member 1 
RDH16                 0.064   retinol dehydrogenase 16 
HSD11B2               0.064   hydroxysteroid (11-beta) dehydrogenase 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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