Guide to the Human Genome
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Search of human proteins with 99028883

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
sapiens]
         (592 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ...  1213   0.0  
gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ...   231   2e-60
gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo ...   202   5e-52
gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo...   202   7e-52
gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo...   194   2e-49
gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo...   191   2e-48
gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo ...   186   4e-47
gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo ...   154   2e-37
gi|212720861 tubulin tyrosine ligase-like family, member 11 a [H...   138   1e-32
gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Ho...   110   3e-24
gi|24308516 tubulin tyrosine ligase [Homo sapiens]                    105   9e-23
gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo...   104   2e-22
gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo...    99   1e-20
gi|194239681 tubulin tyrosine ligase-like family, member 10 isof...    92   1e-18
gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo...    78   2e-14
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo...    72   1e-12
gi|194239678 tubulin tyrosine ligase-like family, member 10 isof...    54   4e-07
gi|130502140 NEZHA isoform 2 [Homo sapiens]                            39   0.010
gi|122937255 NEZHA isoform 1 [Homo sapiens]                            39   0.010
gi|49170034 integrin, alpha 8 [Homo sapiens]                           33   0.96 
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom...    32   1.3  
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom...    32   1.3  
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo...    32   1.3  
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo...    32   1.3  
gi|110349719 titin isoform N2-A [Homo sapiens]                         32   1.6  
gi|11560152 zinc finger protein 335 [Homo sapiens]                     32   2.1  
gi|169167201 PREDICTED: hypothetical protein [Homo sapiens]            31   2.8  
gi|169166894 PREDICTED: hypothetical protein [Homo sapiens]            31   2.8  
gi|169166324 PREDICTED: hypothetical protein [Homo sapiens]            31   2.8  
gi|239750706 PREDICTED: hypothetical protein XP_002347489 [Homo ...    30   4.8  

>gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
           sapiens]
          Length = 592

 Score = 1213 bits (3138), Expect = 0.0
 Identities = 592/592 (100%), Positives = 592/592 (100%)

Query: 1   MRGRDLCSSTQSQALGSLRTTTPAFTLNIPSEANHTEQPPAGLGARLQEAGVSIPPRRGR 60
           MRGRDLCSSTQSQALGSLRTTTPAFTLNIPSEANHTEQPPAGLGARLQEAGVSIPPRRGR
Sbjct: 1   MRGRDLCSSTQSQALGSLRTTTPAFTLNIPSEANHTEQPPAGLGARLQEAGVSIPPRRGR 60

Query: 61  PTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTPAVVQSVLLERGWNKFDKQEQNAED 120
           PTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTPAVVQSVLLERGWNKFDKQEQNAED
Sbjct: 61  PTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTPAVVQSVLLERGWNKFDKQEQNAED 120

Query: 121 WNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPL 180
           WNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPL
Sbjct: 121 WNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPL 180

Query: 181 TFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQ 240
           TFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQ
Sbjct: 181 TFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQ 240

Query: 241 KYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNS 300
           KYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNS
Sbjct: 241 KYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNS 300

Query: 301 SINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSV 360
           SINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSV
Sbjct: 301 SINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSV 360

Query: 361 PFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGL 420
           PFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGL
Sbjct: 361 PFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGL 420

Query: 421 RNEGREASNATHGNSNIDAAKSDRGGLDAPDCLPYDSLSFTSRMYNEDDSVVEKAVSVRP 480
           RNEGREASNATHGNSNIDAAKSDRGGLDAPDCLPYDSLSFTSRMYNEDDSVVEKAVSVRP
Sbjct: 421 RNEGREASNATHGNSNIDAAKSDRGGLDAPDCLPYDSLSFTSRMYNEDDSVVEKAVSVRP 480

Query: 481 EAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPC 540
           EAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPC
Sbjct: 481 EAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPC 540

Query: 541 VLSDRGKAPDPQAGNFVLVFPFNEATLGASRNGLNVKRIIQELQKLMNKQHS 592
           VLSDRGKAPDPQAGNFVLVFPFNEATLGASRNGLNVKRIIQELQKLMNKQHS
Sbjct: 541 VLSDRGKAPDPQAGNFVLVFPFNEATLGASRNGLNVKRIIQELQKLMNKQHS 592


>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
           sapiens]
          Length = 1281

 Score =  231 bits (588), Expect = 2e-60
 Identities = 125/341 (36%), Positives = 195/341 (57%), Gaps = 22/341 (6%)

Query: 87  LVFRVDETTPAVVQSVLLERGWNKFDKQEQNAEDWNLYWRTSSFRMTEHNSVKPWQQLNH 146
           L +++  T   +V+S+L   G   F +   ++ D+NL W  S  +     ++   Q++NH
Sbjct: 65  LSYKIVRTDSRLVRSILTAHG---FHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVNH 121

Query: 147 HPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLTFVMPNDYTKFVAEYFQERQMLGTKH 206
            P + +LTRKD L K++  M+  +G   +  +P TF++P +Y +F   Y ++R       
Sbjct: 122 FPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDR------- 174

Query: 207 SYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFK 266
             WI KP   SRGRG+ + ++      ++  +V +YI+NPLLI  +K D+R+YV VT + 
Sbjct: 175 GPWIVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYD 234

Query: 267 PLTIYVYQEGLVRFATEKFD--LSNLQNNYAHLTNSSINKSGASYEKI--KEVIGHGCKW 322
           PL IY+Y+EGL RFAT ++D    N++N + HLTN S+NK    Y      EV  +G KW
Sbjct: 235 PLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKW 294

Query: 323 TLSRFFSYLRSWDVDDLLLWKKIHRMVILTI----LAIAPS----VPFAANCFELFGFDI 374
           ++S    YL+    D   L   +  ++I TI    LAIA +    VP  ++CFEL+GFD+
Sbjct: 295 SMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDV 354

Query: 375 LIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLI 415
           LID  LKPWLLEVN SP+L  D   D+ +K  ++ D+  ++
Sbjct: 355 LIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVV 395


>gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo
           sapiens]
          Length = 423

 Score =  202 bits (515), Expect = 5e-52
 Identities = 128/364 (35%), Positives = 194/364 (53%), Gaps = 57/364 (15%)

Query: 98  VVQSVLL----ERGWNKFDKQEQNAEDWNLYWRT-----SSFRMTEHNSVKPWQQLNHHP 148
           + +SVL+    +RGW     Q    EDWN YW +     + F +     +   Q +NH P
Sbjct: 11  IEKSVLINNFEKRGW----VQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFP 66

Query: 149 GTTKLTRKDCLAKHLKHMRRMY-------------GTSLY-QFIPLTFVMPNDYTKFVAE 194
              +LTRKD + K++K  R+               G  LY  F+P+T+++P DY  FV E
Sbjct: 67  NHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEE 126

Query: 195 YFQERQMLGTKHSYWICKPAELSRGRGILIFS----------DFKDFIF-----DDMYIV 239
           + +      +  S WI KP   ++G+GI + +          D K   F      + Y++
Sbjct: 127 FRK------SPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI 180

Query: 240 QKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKF--DLSNLQNNYAHL 297
             YI+NPLLIG  K DLR+YV V+ ++PL  Y+Y+ G  RF T K+    S L N + HL
Sbjct: 181 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL 240

Query: 298 TNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLL--LWKKIHRMVILTILA 355
           TN +I K G  Y  I     HG KWT+S    YL S    ++   L+ +IH +++ ++ A
Sbjct: 241 TNVAIQKHGEDYNHI-----HGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKA 295

Query: 356 IAPSVPFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLI 415
           +AP +    +CFE +G+DI+IDD LKPWL+EVN SP+LT   + D ++K  L++D +++ 
Sbjct: 296 VAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIA 355

Query: 416 YLNG 419
             NG
Sbjct: 356 VPNG 359


>gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo
           sapiens]
          Length = 1199

 Score =  202 bits (514), Expect = 7e-52
 Identities = 121/347 (34%), Positives = 194/347 (55%), Gaps = 34/347 (9%)

Query: 85  KPLVFRVDETTPAVVQSVLLERGWNKFDKQEQNAEDWNLYW----RTSSFRMTEHNSVKP 140
           K L +++   TP +V+  +   G + F   ++N +DW   W    ++ SFR     S++ 
Sbjct: 605 KLLRWKMSTVTPNIVKQTI---GRSHFKISKRN-DDWLGCWGHHMKSPSFR-----SIRE 655

Query: 141 WQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLTFVMPNDYTKFVAEYFQERQ 200
            Q+LNH PG+ ++ RKD L ++L  M+  +G   + F P +F++P D  K + + ++   
Sbjct: 656 HQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQD-AKLLRKAWES-- 712

Query: 201 MLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQKYISNPLLIGRYKCDLRIYV 260
              +    WI KP   +RG GI +   +         +VQ+Y+  P LI   K DLRIYV
Sbjct: 713 ---SSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYV 769

Query: 261 CVTGFKPLTIYVYQEGLVRFATEKF--DLSNLQNNYAHLTNSSINKSGASYE-KIKEVIG 317
            VT + PL IY++ +GLVRFA+ K+   + +L N + HLTN S+NK  A Y+    E+  
Sbjct: 770 YVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMAC 829

Query: 318 HGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSV----------PFAANCF 367
            G KW L   ++YL    V+   +W+KI  +V+ TI++  P V          P+  +C 
Sbjct: 830 QGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPY--SCH 887

Query: 368 ELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDL 414
           ELFGFDI++D+NLKPW+LEVN SP+L      D+ +K +++ D+++L
Sbjct: 888 ELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNL 934


>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
           1 [Homo sapiens]
          Length = 891

 Score =  194 bits (493), Expect = 2e-49
 Identities = 133/410 (32%), Positives = 202/410 (49%), Gaps = 46/410 (11%)

Query: 119 EDWNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFI 178
           +DW LYW   S  +     +K +Q++NH PG +++ RKD LA+++  M +M+    ++F 
Sbjct: 137 DDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKMFPKD-FRFF 195

Query: 179 PLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYI 238
           P T+ +P D+   +  Y + R     K+  +ICKP    +G+GI I    K+    +  I
Sbjct: 196 PRTWCLPADWGD-LQTYSRSR-----KNKTYICKPDSGCQGKGIFITRTVKEIKPGEDMI 249

Query: 239 VQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFD---LSNLQNNYA 295
            Q YIS P +I  +K DLRIYV VT   PL I+VY EGL RFAT  +      NL +   
Sbjct: 250 CQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICM 309

Query: 296 HLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILA 355
           HLTN SINK  +++ +       G K  LS F +YL     +   +W+ I  ++I T+++
Sbjct: 310 HLTNYSINKHSSNFSRDAH---SGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLIS 366

Query: 356 IAPSV-----------PFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVK 404
             P +              + CFE+ GFDIL+D  LKPWLLEVN+SP+ + D   D  VK
Sbjct: 367 AHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVK 426

Query: 405 RKLVHDIIDLIYLNGL---------RNEGREASNATHGNSNIDAAKSDRG-------GLD 448
             L++D + LI L            R  G+           I+ AK  R          +
Sbjct: 427 DGLLYDTLVLINLESCDKKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYE 486

Query: 449 APDC----LPYDSLSFT--SRMYNEDDSVVEKAVSVRPEAAPASQLEGEM 492
             +C    L Y SL+     + + +++S+ +  V+ R     A QL  E+
Sbjct: 487 KENCGGFRLIYPSLNSEKYEKFFQDNNSLFQNTVASRAREEYARQLIQEL 536


>gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo
           sapiens]
          Length = 459

 Score =  191 bits (485), Expect = 2e-48
 Identities = 124/324 (38%), Positives = 176/324 (54%), Gaps = 28/324 (8%)

Query: 113 KQEQNAEDWNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGT 172
           K+    E+W LYW   +  +     +K +Q++NH PG T++ RKD LA++L  M ++Y  
Sbjct: 110 KEVGEDEEWTLYWTDCAVSLERVMDMKRFQKINHFPGMTEICRKDLLARNLNRMYKLY-P 168

Query: 173 SLYQFIPLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFI 232
           S Y   P T+ +P DY  F + Y ++R     K   +ICKP    +GRGI I  + ++  
Sbjct: 169 SEYNIFPRTWCLPADYGDFQS-YGRQR-----KARTYICKPDSGCQGRGIFITRNPREIK 222

Query: 233 FDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKF---DLSN 289
             +  I Q+YIS PLLI  +K D+R+YV +T   PL I+ Y+EGL RFAT  +     +N
Sbjct: 223 PGEHMICQQYISKPLLIDGFKFDMRVYVLITSCDPLRIFTYEEGLARFATTPYMEPSHNN 282

Query: 290 LQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMV 349
           L N   HLTN +INK   ++ +   V   G K  LS    +L+    +   LW  I  ++
Sbjct: 283 LDNVCMHLTNYAINKHNENFVRDGAV---GSKRKLSTLNIWLQEHSYNPGELWGDIEDII 339

Query: 350 ILTILAIAPSV---------PFAAN-----CFELFGFDILIDDNLKPWLLEVNYSPALTL 395
           I TI++ A SV         P   N     CFE+ GFDIL+D  LKPWLLEVN+SP+ T 
Sbjct: 340 IKTIIS-AHSVLRHNYRTCFPQYLNGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFTT 398

Query: 396 DCSTDVLVKRKLVHDIIDLIYLNG 419
           D   D  VK  L+ D + L+ L G
Sbjct: 399 DSCLDQEVKDALLCDAMTLVNLRG 422


>gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo
           sapiens]
          Length = 887

 Score =  186 bits (473), Expect = 4e-47
 Identities = 120/362 (33%), Positives = 190/362 (52%), Gaps = 29/362 (8%)

Query: 98  VVQSVLLERGWNKFDKQEQNAEDWNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKD 157
           +V+ V+ E G+ K   +++ +   NL W  S+ +  + + ++ +Q++NH PG  ++ RKD
Sbjct: 52  IVRLVIDEMGFMKTPDEDETS---NLIWCDSAVQQEKISELQNYQRINHFPGMGEICRKD 108

Query: 158 CLAKHLKHMRRMYGTSLYQFIPLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELS 217
            LA+++  M +      Y F+P T++ P +YT+F   Y +E +    K   +I KPA  +
Sbjct: 109 FLARNMTKMIKSRPLD-YTFVPRTWIFPAEYTQF-QNYVKELKKK-RKQKTFIVKPANGA 165

Query: 218 RGRGILIFSDFKDFIFDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGL 277
            G GI +  +       D  IVQ+YI  P L+  YK DLRIY+ VT   PL I++Y +GL
Sbjct: 166 MGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGL 225

Query: 278 VRFATEKF---DLSNLQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSW 334
           VR  TEK+   + SNL   Y HLTN S+NK    +E+  E    G K ++  F  +L++ 
Sbjct: 226 VRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFER-DETENKGSKRSIKWFTEFLQAN 284

Query: 335 DVDDLLLWKKIHRMVILTILAIAPSVPFA-------------ANCFELFGFDILIDDNLK 381
             D    W  I  +V+ T++   P V  A             + CFE+ GFDIL+D  LK
Sbjct: 285 QHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLK 344

Query: 382 PWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYL------NGLRNEGREASNATHGNS 435
           PWLLE+N +P+   D   D  VKR ++ + + L+ +        L  +  EA    +G +
Sbjct: 345 PWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQKAEAQRRLYGQN 404

Query: 436 NI 437
           +I
Sbjct: 405 SI 406


>gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo
           sapiens]
          Length = 439

 Score =  154 bits (389), Expect = 2e-37
 Identities = 115/365 (31%), Positives = 175/365 (47%), Gaps = 59/365 (16%)

Query: 90  RVDETTPAVVQSVLLER-GWNKFDKQEQNAEDWNLYWRTSSFRMT--EHNSVKPWQQLNH 146
           R   T    +  VL  R GW     + ++  +W+ YW   S+     +H  +    +++H
Sbjct: 45  RFKTTLMNTLMDVLRHRPGW----VEVKDEGEWDFYWCDVSWLRENFDHTYMDEHVRISH 100

Query: 147 HPGTTKLTRKDCLAKHLKHMRRMYG-------TSLYQFIPLTFVMPNDYTKFVAEYFQER 199
                +LTRK+ + K+LK  R+           +   F P TF MP +Y  FV E+ +  
Sbjct: 101 FRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPKTFEMPCEYHLFVEEFRKNP 160

Query: 200 QMLGTKHSYWICKPAELSRGRGILIFSDFKDFIF------------DDM----YIVQKYI 243
            +       WI KP   S+G+GI +F   KD +             DD+    Y+ Q+YI
Sbjct: 161 GIT------WIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYI 214

Query: 244 SNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSIN 303
            NP LIG  K DLR+YV       L + V+ E L+     + D+        HLTN ++ 
Sbjct: 215 ENPYLIGGRKFDLRVYV-------LVMSVFAECLLWSGHRRQDV--------HLTNVAVQ 259

Query: 304 KSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLL--LWKKIHRMVILTILAIAPSVP 361
           K+   Y   K     GCKWTL RF  YL S    + +  L++ I  + + ++ ++   + 
Sbjct: 260 KTSPDYHPKK-----GCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQKVII 314

Query: 362 FAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGLR 421
              +CFEL+G+DILID +LKPWLLEVN SP+LT     D  +K  L+ D + ++ +   R
Sbjct: 315 SDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEA-R 373

Query: 422 NEGRE 426
             GRE
Sbjct: 374 LTGRE 378


>gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo
           sapiens]
          Length = 800

 Score =  138 bits (348), Expect = 1e-32
 Identities = 95/298 (31%), Positives = 149/298 (50%), Gaps = 33/298 (11%)

Query: 122 NLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLT 181
           ++YW   SF   +  S     Q+N  PG T++ RK  L++ ++ M+ ++    Y F P +
Sbjct: 254 DIYWHGVSFHDNDIFS----GQVNKFPGMTEMVRKITLSRAVRTMQNLFPEE-YNFYPRS 308

Query: 182 FVMPNDYTKFVAEYFQERQMLGTKHSYW----ICKPAELSRGRGILIFSDFKDF-----I 232
           +++P+++  FVA+     QM+      W    I KP    +G GI +  D  D      +
Sbjct: 309 WILPDEFQLFVAQV----QMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTL 364

Query: 233 FDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFD---LSN 289
                +VQ+YI  PLLI + K D+R+YV +    PL IY+ ++GL RF TE +      N
Sbjct: 365 QSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKN 424

Query: 290 LQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMV 349
           L   + HLTN S+N    ++    +    G K T S     L S  VD   +W  I  +V
Sbjct: 425 LHRIFMHLTNYSLNIHSGNFIH-SDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVV 483

Query: 350 ILTILAIAPSVPF-----------AANCFELFGFDILIDDNLKPWLLEVNYSPALTLD 396
           I T++A+ P +                CF++ GFDIL+  NLKP LLEVN +P++ ++
Sbjct: 484 IKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIE 541


>gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Homo
           sapiens]
          Length = 538

 Score =  110 bits (276), Expect = 3e-24
 Identities = 78/251 (31%), Positives = 124/251 (49%), Gaps = 22/251 (8%)

Query: 122 NLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLT 181
           ++YW   SF   +  S     Q+N  PG T++ RK  L++ ++ M+ ++    Y F P +
Sbjct: 254 DIYWHGVSFHDNDIFS----GQVNKFPGMTEMVRKITLSRAVRTMQNLFPEE-YNFYPRS 308

Query: 182 FVMPNDYTKFVAEYFQERQMLGTKHSYW----ICKPAELSRGRGILIFSDFKDF-----I 232
           +++P+++  FVA+     QM+      W    I KP    +G GI +  D  D      +
Sbjct: 309 WILPDEFQLFVAQV----QMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTL 364

Query: 233 FDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFD---LSN 289
                +VQ+YI  PLLI + K D+R+YV +    PL IY+ ++GL RF TE +      N
Sbjct: 365 QSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKN 424

Query: 290 LQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMV 349
           L   + HLTN S+N    ++    +    G K T S     L S  VD   +W  I  +V
Sbjct: 425 LHRIFMHLTNYSLNIHSGNFIH-SDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVV 483

Query: 350 ILTILAIAPSV 360
           I T++A+ P +
Sbjct: 484 IKTVIALTPEL 494


>gi|24308516 tubulin tyrosine ligase [Homo sapiens]
          Length = 377

 Score =  105 bits (263), Expect = 9e-23
 Identities = 87/286 (30%), Positives = 141/286 (49%), Gaps = 43/286 (15%)

Query: 142 QQLNHHPGTTKLTRKDCLAKHLKHMRRM-------------YGTSLYQFI---------P 179
           Q +N++ G  KL RK  L K +K    +             Y T+L   +         P
Sbjct: 60  QLVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPP 119

Query: 180 LTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFK---DFIFDD- 235
           ++    ++   F+A Y ++++    + + WI K +  ++G GILI S+     DFI +  
Sbjct: 120 ISNSRTDEREFFLASYNRKKE--DGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQG 177

Query: 236 -MYIVQKYISNPLLI--GRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQN 292
            ++++QKY+ +PLL+  G  K D+R +V V       IY+Y+EG++R A+E + + N Q+
Sbjct: 178 QVHVIQKYLEHPLLLEPGHRKFDIRSWVLVD--HQYNIYLYREGVLRTASEPYHVDNFQD 235

Query: 293 NYAHLTNSSINKS-GASYEKIKEVIGHGCKWTLSRFFSYLRS-----WDVDDLLLWKKIH 346
              HLTN  I K    +Y K +E    G +     F  YL S      +   LL  K I 
Sbjct: 236 KTCHLTNHCIQKEYSKNYGKYEE----GNEMFFKEFNQYLTSALNITLESSILLQIKHII 291

Query: 347 RMVILTILAIAPSVPFAANCFELFGFDILIDDNLKPWLLEVNYSPA 392
           R  +L++     +       F+LFGFD ++D+ LK WL+EVN +PA
Sbjct: 292 RNCLLSVEPAISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPA 337


>gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo
           sapiens]
          Length = 772

 Score =  104 bits (260), Expect = 2e-22
 Identities = 63/198 (31%), Positives = 101/198 (51%), Gaps = 14/198 (7%)

Query: 209 WICKPAELSRGRGILIFSDFKDFIF----------DDMYIVQKYISNPLLIGRYKCDLRI 258
           WI KP   SRGRGI+     ++ +           D  ++VQKYI  PLLI   K DLR 
Sbjct: 280 WIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVVQKYIERPLLIFGTKFDLRQ 339

Query: 259 YVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSINKSGASYEKIKEVIGH 318
           +  VT + PLT++ Y++  +RF+T+ F L NL N+  HL N+SI K   +      ++  
Sbjct: 340 WFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNS-VHLCNNSIQKHLENSCHRHPLLPP 398

Query: 319 GCKWTLSRFFSYLRSWDVDD---LLLWKKIHRMVILTILAIAPSVPFAANCFELFGFDIL 375
              W+  RF ++L+     +    ++   +   VI  +     +V      FEL+G D +
Sbjct: 399 DNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKASFELYGADFV 458

Query: 376 IDDNLKPWLLEVNYSPAL 393
             ++ +PWL+E+N SP +
Sbjct: 459 FGEDFQPWLIEINASPTM 476


>gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo
           sapiens]
          Length = 834

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 64/202 (31%), Positives = 104/202 (51%), Gaps = 18/202 (8%)

Query: 209 WICKPAELSRGRGI---LIFSDFKDFIF-----------DDMYIVQKYISNPLLIGRYKC 254
           WI KPA  SRGRG    ++  D  + I            D+ ++VQKYI  PLLI   K 
Sbjct: 331 WIIKPAAKSRGRGESPDIVCMDRVEEILELAAADHPLSRDNKWVVQKYIETPLLICDTKF 390

Query: 255 DLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSINKSGASYEKIKE 314
           D+R +  VT + PLTI+ Y+E  +RF+T++F L  L ++  HL N+++ K   +      
Sbjct: 391 DIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDKL-DSAIHLCNNAVQKYLKNDVGRSP 449

Query: 315 VIGHGCKWTLSRFFSYLRSWD---VDDLLLWKKIHRMVILTILAIAPSVPFAANCFELFG 371
           ++     WT +RF  YL+      V   +++  + + +   +      V    N FEL+G
Sbjct: 450 LLPAHNMWTSTRFQEYLQRQGRGAVWGSVIYPSMKKAIAHAMKVAQDHVEPRKNSFELYG 509

Query: 372 FDILIDDNLKPWLLEVNYSPAL 393
            D ++  + +PWL+E+N SP +
Sbjct: 510 ADFVLGRDFRPWLIEINSSPTM 531


>gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform
           1 [Homo sapiens]
          Length = 673

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 99/418 (23%), Positives = 160/418 (38%), Gaps = 91/418 (21%)

Query: 79  PSGALLKPLVFRVDETTP-----------------AVVQSVLLERGWNKFDKQEQNAEDW 121
           PS ALL+ L+    + +P                  ++ S    +GW +    +   +D+
Sbjct: 133 PSAALLEGLLLGGGKPSPHSTRPGPFFYIGGSNGATIISSYCKSKGWQRI--HDSRRDDY 190

Query: 122 NLYWRTSSFRMTEHNSVKPWQQLNHH-PGTTKLTRKDCLAKHLKHMRRMYGTS------- 173
            L W     R   + S +  +QL +  P    LT K  L   L+   R    +       
Sbjct: 191 TLKWCEVKSR-DSYGSFREGEQLLYQLPNNKLLTTKIGLLSTLRGRARAMSKASKVPGGV 249

Query: 174 -----------LYQFIPLT---FVMPNDYTKFVAEYFQERQMLGTKHS------------ 207
                        + +P T   ++ P    + + E+F E   L  KH             
Sbjct: 250 QARLEKDAAAPALEDLPWTSPGYLRPQRVLR-MEEFFPETYRLDLKHEREAFFTLFDETQ 308

Query: 208 YWICKPAELSRGRGILIFSDFKD---------------------FIFDDMYIVQKYISNP 246
            WICKP   ++G+GI +  + ++                     F      +VQ+YI NP
Sbjct: 309 IWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNP 368

Query: 247 LLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSINKSG 306
           LL+   K D+R Y+ +    P  I+ +  G  R     +D  +  +   HLTN  + K  
Sbjct: 369 LLVDGRKFDVRSYLLIACTTPYMIF-FGHGYARLTLSLYD-PHSSDLGGHLTNQFMQKKS 426

Query: 307 ASYEKIKEVIGHGCKWTLSRFFSYLRS--WDVDDLL-------LWKKIHRMVILTILAIA 357
             Y  +KE       W++     Y+    W    L        L K++ +++    LA  
Sbjct: 427 PLYMLLKE----HTVWSMEHLNRYISDTFWKARGLAKDWVFTTLKKRMQQIMAHCFLAAK 482

Query: 358 PSVPFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLI 415
           P +      F+L G D LIDDN K WLLE+N +PAL  +C     V   +V + +DL+
Sbjct: 483 PKLDCKLGYFDLIGCDFLIDDNFKVWLLEMNSNPALHTNCEVLKEVIPGVVIETLDLV 540


>gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo
           sapiens]
          Length = 644

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 14/192 (7%)

Query: 116 QNAEDWNLYWRTSSFR-MTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSL 174
           Q+  D ++ +  S F+   + +  +P   LN  P    LT KDCLA      RR  G   
Sbjct: 327 QSEADADILFNFSHFKDYRKLSQERPGVLLNQFPCENLLTVKDCLASIA---RRAGGPEG 383

Query: 175 YQFIPLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIF- 233
             ++P TF +  +  +FV+ YFQ+R+  G + ++WICKP  L+R     +       I  
Sbjct: 384 PPWLPRTFNLRTELPQFVS-YFQQRERWG-EDNHWICKPWNLARSLDTHVTKSLHSIIRH 441

Query: 234 --DDMYIVQKYISNPLL-----IGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFD 286
                 +V KYI +P+L     +G+ K D+R  V +   +PL ++VY    +RF+   F 
Sbjct: 442 RESTPKVVSKYIESPVLFLREDVGKVKFDIRYIVLLRSVRPLRLFVYDVFWLRFSNRAFA 501

Query: 287 LSNLQNNYAHLT 298
           L++L +   H T
Sbjct: 502 LNDLDDYEKHFT 513


>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
           2 [Homo sapiens]
          Length = 584

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 57/202 (28%), Positives = 90/202 (44%), Gaps = 33/202 (16%)

Query: 324 LSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSV-----------PFAANCFELFGF 372
           LS F +YL     +   +W+ I  ++I T+++  P +              + CFE+ GF
Sbjct: 28  LSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEILGF 87

Query: 373 DILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGL---------RNE 423
           DIL+D  LKPWLLEVN+SP+ + D   D  VK  L++D + LI L            R  
Sbjct: 88  DILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLINLESCDKKKVLEEERQR 147

Query: 424 GREASNATHGNSNIDAAKSDRG-------GLDAPDC----LPYDSLSFT--SRMYNEDDS 470
           G+           I+ AK  R          +  +C    L Y SL+     + + +++S
Sbjct: 148 GQFLQQCCSREMRIEEAKGFRAVQLKKTETYEKENCGGFRLIYPSLNSEKYEKFFQDNNS 207

Query: 471 VVEKAVSVRPEAAPASQLEGEM 492
           + +  V+ R     A QL  E+
Sbjct: 208 LFQNTVASRAREEYARQLIQEL 229


>gi|194239678 tubulin tyrosine ligase-like family, member 10 isoform
           2 [Homo sapiens]
          Length = 404

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 75/357 (21%), Positives = 126/357 (35%), Gaps = 90/357 (25%)

Query: 79  PSGALLKPLVFRVDETTP-----------------AVVQSVLLERGWNKFDKQEQNAEDW 121
           PS ALL+ L+    + +P                  ++ S    +GW +    +   +D+
Sbjct: 60  PSAALLEGLLLGGGKPSPHSTRPGPFFYIGGSNGATIISSYCKSKGWQRI--HDSRRDDY 117

Query: 122 NLYWRTSSFRMTEHNSVKPWQQLNHH-PGTTKLTRKDCLAKHLKHMRRMYGTS------- 173
            L W     R   + S +  +QL +  P    LT K  L   L+   R    +       
Sbjct: 118 TLKWCEVKSR-DSYGSFREGEQLLYQLPNNKLLTTKIGLLSTLRGRARAMSKASKVPGGV 176

Query: 174 -----------LYQFIPLT---FVMPNDYTKFVAEYFQERQMLGTKHS------------ 207
                        + +P T   ++ P    + + E+F E   L  KH             
Sbjct: 177 QARLEKDAAAPALEDLPWTSPGYLRPQRVLR-MEEFFPETYRLDLKHEREAFFTLFDETQ 235

Query: 208 YWICKPAELSRGRGILIFSDFKD---------------------FIFDDMYIVQKYISNP 246
            WICKP   ++G+GI +  + ++                     F      +VQ+YI NP
Sbjct: 236 IWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNP 295

Query: 247 LLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSINKSG 306
           LL+   K D+R Y+ +    P  I+ +  G  R     +D  +  +   HLTN  + K  
Sbjct: 296 LLVDGRKFDVRSYLLIACTTPYMIF-FGHGYARLTLSLYD-PHSSDLGGHLTNQFMQKKS 353

Query: 307 ASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKK--IHRMVILTILAIAPSVP 361
             Y  +KE       W++     Y+          WK   + +  + T L + P  P
Sbjct: 354 PLYMLLKE----HTVWSMEHLNRYISD------TFWKARGLAKDWVFTTLKVRPLCP 400


>gi|130502140 NEZHA isoform 2 [Homo sapiens]
          Length = 1249

 Score = 39.3 bits (90), Expect = 0.010
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 9/95 (9%)

Query: 468 DDSVVEKAVSVRPEAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPY--- 524
           D   +E+A+ +   A P    +G   G  F+L + E P SKP L S + P  T  P    
Sbjct: 455 DLPTIEEALQIIHSAEPRLLPDGAADGS-FYLHSPEGP-SKPSLASPYLPEGTSKPLSDR 512

Query: 525 ---ASLFQSH-SCKTKTSPCVLSDRGKAPDPQAGN 555
              A ++  H    +K SPC++ +  K P P  G+
Sbjct: 513 PTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGS 547


>gi|122937255 NEZHA isoform 1 [Homo sapiens]
          Length = 1276

 Score = 39.3 bits (90), Expect = 0.010
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 9/95 (9%)

Query: 468 DDSVVEKAVSVRPEAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPY--- 524
           D   +E+A+ +   A P    +G   G  F+L + E P SKP L S + P  T  P    
Sbjct: 482 DLPTIEEALQIIHSAEPRLLPDGAADGS-FYLHSPEGP-SKPSLASPYLPEGTSKPLSDR 539

Query: 525 ---ASLFQSH-SCKTKTSPCVLSDRGKAPDPQAGN 555
              A ++  H    +K SPC++ +  K P P  G+
Sbjct: 540 PTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGS 574


>gi|49170034 integrin, alpha 8 [Homo sapiens]
          Length = 1063

 Score = 32.7 bits (73), Expect = 0.96
 Identities = 18/64 (28%), Positives = 35/64 (54%), Gaps = 4/64 (6%)

Query: 45  ARLQEAGVSIPPRRGRPTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTPAVVQSVLL 104
           A+++  GVS PP+   P    E +++PH   ++E  G L++  ++ +    P+ +   +L
Sbjct: 785 AQVEIRGVSHPPQIVLPIHNWEPEEEPH---KEEEVGPLVEH-IYELHNIGPSTISDTIL 840

Query: 105 ERGW 108
           E GW
Sbjct: 841 EVGW 844


>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
           sapiens]
          Length = 841

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 483 APASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPCVL 542
           +P +Q++ E + Q  +LS+R  P++   ++S  +P + L P           +KTSP  L
Sbjct: 424 SPVTQVKDEAAAQPLNLSSR--PKTAEPVKSPTSPTQNLFP----------ASKTSPVNL 471

Query: 543 SDRGKAPDPQAGN 555
            ++   P P  G+
Sbjct: 472 PNKSSIPSPIGGS 484


>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
           sapiens]
          Length = 801

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 483 APASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPCVL 542
           +P +Q++ E + Q  +LS+R  P++   ++S  +P + L P           +KTSP  L
Sbjct: 370 SPVTQVKDEAAAQPLNLSSR--PKTAEPVKSPTSPTQNLFP----------ASKTSPVNL 417

Query: 543 SDRGKAPDPQAGN 555
            ++   P P  G+
Sbjct: 418 PNKSSIPSPIGGS 430


>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
           sapiens]
          Length = 804

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 483 APASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPCVL 542
           +P +Q++ E + Q  +LS+R  P++   ++S  +P + L P           +KTSP  L
Sbjct: 373 SPVTQVKDEAAAQPLNLSSR--PKTAEPVKSPTSPTQNLFP----------ASKTSPVNL 420

Query: 543 SDRGKAPDPQAGN 555
            ++   P P  G+
Sbjct: 421 PNKSSIPSPIGGS 433


>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
           sapiens]
          Length = 808

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 12/73 (16%)

Query: 483 APASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPCVL 542
           +P +Q++ E + Q  +LS+R  P++   ++S  +P + L P           +KTSP  L
Sbjct: 411 SPVTQVKDEAAAQPLNLSSR--PKTAEPVKSPTSPTQNLFP----------ASKTSPVNL 458

Query: 543 SDRGKAPDPQAGN 555
            ++   P P  G+
Sbjct: 459 PNKSSIPSPIGGS 471


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 7/67 (10%)

Query: 37   EQPPAGLGARLQEAGVSIPPRRGRPTPTLEKKKKPHLMAEDEPSGAL----LKPLVFRVD 92
            E+PP    A++ EA   I P +  P P  +K+K P     +EP   +    + P V +++
Sbjct: 9573 EEPPP---AKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKME 9629

Query: 93   ETTPAVV 99
            E  PA V
Sbjct: 9630 EPLPAKV 9636


>gi|11560152 zinc finger protein 335 [Homo sapiens]
          Length = 1342

 Score = 31.6 bits (70), Expect = 2.1
 Identities = 22/58 (37%), Positives = 25/58 (43%), Gaps = 3/58 (5%)

Query: 31  SEANHTEQPPAGLGARLQEAGVSIPPRRGRPTPTLEKKKKPHLMAEDEPSGALLKPLV 88
           S+ N  E  P G   RLQ    S P  R RP      +K P L   D P G   +PLV
Sbjct: 321 SDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPG---RPRKLPRLEISDLPDGVEGEPLV 375


>gi|169167201 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 145

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 1/81 (1%)

Query: 473 EKAVSVRPEAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHS 532
           E+A    PEA   + L+ +++  D  +S+  +P ++PKLR R    + L  YA+      
Sbjct: 3   ERAGGKNPEAPDTAPLDEKLASSDDSISSA-IPPTRPKLRRRKGDTERLTDYATARARAQ 61

Query: 533 CKTKTSPCVLSDRGKAPDPQA 553
             +  +    S R  AP   A
Sbjct: 62  PASSAAQLPRSHRPPAPSAPA 82


>gi|169166894 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 145

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 1/81 (1%)

Query: 473 EKAVSVRPEAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHS 532
           E+A    PEA   + L+ +++  D  +S+  +P ++PKLR R    + L  YA+      
Sbjct: 3   ERAGGKNPEAPDTAPLDEKLASSDDSISSA-IPPTRPKLRRRKGDTERLRDYATARARAQ 61

Query: 533 CKTKTSPCVLSDRGKAPDPQA 553
             +  +    S R  AP   A
Sbjct: 62  PASSAAQLPRSHRPPAPSAPA 82


>gi|169166324 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 145

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 1/81 (1%)

Query: 473 EKAVSVRPEAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHS 532
           E+A    PEA   + L+ +++  D  +S+  +P ++PKLR R    + L  YA+      
Sbjct: 3   ERAGGKNPEAPDTAPLDEKLASSDDSISSA-IPPTRPKLRRRKGDTERLRDYATARARAQ 61

Query: 533 CKTKTSPCVLSDRGKAPDPQA 553
             +  +    S R  AP   A
Sbjct: 62  PASSAAQLPRSHRPPAPSAPA 82


>gi|239750706 PREDICTED: hypothetical protein XP_002347489 [Homo
           sapiens]
          Length = 133

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 7/60 (11%)

Query: 37  EQPPAGLGARLQEAGVSIPPRRGRPTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTP 96
           ++  A +G RL+EA + IPP    P+    +K   HL       GA+L PL   + E  P
Sbjct: 59  QEQDAHVGPRLEEAWIQIPP---VPSTRRARKAISHL----RKPGAVLSPLTCELQEKLP 111


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,467,724
Number of Sequences: 37866
Number of extensions: 1104685
Number of successful extensions: 3098
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 3016
Number of HSP's gapped (non-prelim): 56
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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