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Search of human proteins with 99028883
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
sapiens]
(592 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ... 1213 0.0
gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ... 231 2e-60
gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo ... 202 5e-52
gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo... 202 7e-52
gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo... 194 2e-49
gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo... 191 2e-48
gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo ... 186 4e-47
gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo ... 154 2e-37
gi|212720861 tubulin tyrosine ligase-like family, member 11 a [H... 138 1e-32
gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Ho... 110 3e-24
gi|24308516 tubulin tyrosine ligase [Homo sapiens] 105 9e-23
gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo... 104 2e-22
gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo... 99 1e-20
gi|194239681 tubulin tyrosine ligase-like family, member 10 isof... 92 1e-18
gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo... 78 2e-14
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo... 72 1e-12
gi|194239678 tubulin tyrosine ligase-like family, member 10 isof... 54 4e-07
gi|130502140 NEZHA isoform 2 [Homo sapiens] 39 0.010
gi|122937255 NEZHA isoform 1 [Homo sapiens] 39 0.010
gi|49170034 integrin, alpha 8 [Homo sapiens] 33 0.96
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 32 1.3
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 32 1.3
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 32 1.3
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 32 1.3
gi|110349719 titin isoform N2-A [Homo sapiens] 32 1.6
gi|11560152 zinc finger protein 335 [Homo sapiens] 32 2.1
gi|169167201 PREDICTED: hypothetical protein [Homo sapiens] 31 2.8
gi|169166894 PREDICTED: hypothetical protein [Homo sapiens] 31 2.8
gi|169166324 PREDICTED: hypothetical protein [Homo sapiens] 31 2.8
gi|239750706 PREDICTED: hypothetical protein XP_002347489 [Homo ... 30 4.8
>gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
sapiens]
Length = 592
Score = 1213 bits (3138), Expect = 0.0
Identities = 592/592 (100%), Positives = 592/592 (100%)
Query: 1 MRGRDLCSSTQSQALGSLRTTTPAFTLNIPSEANHTEQPPAGLGARLQEAGVSIPPRRGR 60
MRGRDLCSSTQSQALGSLRTTTPAFTLNIPSEANHTEQPPAGLGARLQEAGVSIPPRRGR
Sbjct: 1 MRGRDLCSSTQSQALGSLRTTTPAFTLNIPSEANHTEQPPAGLGARLQEAGVSIPPRRGR 60
Query: 61 PTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTPAVVQSVLLERGWNKFDKQEQNAED 120
PTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTPAVVQSVLLERGWNKFDKQEQNAED
Sbjct: 61 PTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTPAVVQSVLLERGWNKFDKQEQNAED 120
Query: 121 WNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPL 180
WNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPL
Sbjct: 121 WNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPL 180
Query: 181 TFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQ 240
TFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQ
Sbjct: 181 TFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQ 240
Query: 241 KYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNS 300
KYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNS
Sbjct: 241 KYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNS 300
Query: 301 SINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSV 360
SINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSV
Sbjct: 301 SINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSV 360
Query: 361 PFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGL 420
PFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGL
Sbjct: 361 PFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGL 420
Query: 421 RNEGREASNATHGNSNIDAAKSDRGGLDAPDCLPYDSLSFTSRMYNEDDSVVEKAVSVRP 480
RNEGREASNATHGNSNIDAAKSDRGGLDAPDCLPYDSLSFTSRMYNEDDSVVEKAVSVRP
Sbjct: 421 RNEGREASNATHGNSNIDAAKSDRGGLDAPDCLPYDSLSFTSRMYNEDDSVVEKAVSVRP 480
Query: 481 EAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPC 540
EAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPC
Sbjct: 481 EAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPC 540
Query: 541 VLSDRGKAPDPQAGNFVLVFPFNEATLGASRNGLNVKRIIQELQKLMNKQHS 592
VLSDRGKAPDPQAGNFVLVFPFNEATLGASRNGLNVKRIIQELQKLMNKQHS
Sbjct: 541 VLSDRGKAPDPQAGNFVLVFPFNEATLGASRNGLNVKRIIQELQKLMNKQHS 592
>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
sapiens]
Length = 1281
Score = 231 bits (588), Expect = 2e-60
Identities = 125/341 (36%), Positives = 195/341 (57%), Gaps = 22/341 (6%)
Query: 87 LVFRVDETTPAVVQSVLLERGWNKFDKQEQNAEDWNLYWRTSSFRMTEHNSVKPWQQLNH 146
L +++ T +V+S+L G F + ++ D+NL W S + ++ Q++NH
Sbjct: 65 LSYKIVRTDSRLVRSILTAHG---FHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVNH 121
Query: 147 HPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLTFVMPNDYTKFVAEYFQERQMLGTKH 206
P + +LTRKD L K++ M+ +G + +P TF++P +Y +F Y ++R
Sbjct: 122 FPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDR------- 174
Query: 207 SYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFK 266
WI KP SRGRG+ + ++ ++ +V +YI+NPLLI +K D+R+YV VT +
Sbjct: 175 GPWIVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYD 234
Query: 267 PLTIYVYQEGLVRFATEKFD--LSNLQNNYAHLTNSSINKSGASYEKI--KEVIGHGCKW 322
PL IY+Y+EGL RFAT ++D N++N + HLTN S+NK Y EV +G KW
Sbjct: 235 PLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKW 294
Query: 323 TLSRFFSYLRSWDVDDLLLWKKIHRMVILTI----LAIAPS----VPFAANCFELFGFDI 374
++S YL+ D L + ++I TI LAIA + VP ++CFEL+GFD+
Sbjct: 295 SMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDV 354
Query: 375 LIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLI 415
LID LKPWLLEVN SP+L D D+ +K ++ D+ ++
Sbjct: 355 LIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVV 395
>gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo
sapiens]
Length = 423
Score = 202 bits (515), Expect = 5e-52
Identities = 128/364 (35%), Positives = 194/364 (53%), Gaps = 57/364 (15%)
Query: 98 VVQSVLL----ERGWNKFDKQEQNAEDWNLYWRT-----SSFRMTEHNSVKPWQQLNHHP 148
+ +SVL+ +RGW Q EDWN YW + + F + + Q +NH P
Sbjct: 11 IEKSVLINNFEKRGW----VQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFP 66
Query: 149 GTTKLTRKDCLAKHLKHMRRMY-------------GTSLY-QFIPLTFVMPNDYTKFVAE 194
+LTRKD + K++K R+ G LY F+P+T+++P DY FV E
Sbjct: 67 NHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEE 126
Query: 195 YFQERQMLGTKHSYWICKPAELSRGRGILIFS----------DFKDFIF-----DDMYIV 239
+ + + S WI KP ++G+GI + + D K F + Y++
Sbjct: 127 FRK------SPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI 180
Query: 240 QKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKF--DLSNLQNNYAHL 297
YI+NPLLIG K DLR+YV V+ ++PL Y+Y+ G RF T K+ S L N + HL
Sbjct: 181 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL 240
Query: 298 TNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLL--LWKKIHRMVILTILA 355
TN +I K G Y I HG KWT+S YL S ++ L+ +IH +++ ++ A
Sbjct: 241 TNVAIQKHGEDYNHI-----HGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKA 295
Query: 356 IAPSVPFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLI 415
+AP + +CFE +G+DI+IDD LKPWL+EVN SP+LT + D ++K L++D +++
Sbjct: 296 VAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIA 355
Query: 416 YLNG 419
NG
Sbjct: 356 VPNG 359
>gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo
sapiens]
Length = 1199
Score = 202 bits (514), Expect = 7e-52
Identities = 121/347 (34%), Positives = 194/347 (55%), Gaps = 34/347 (9%)
Query: 85 KPLVFRVDETTPAVVQSVLLERGWNKFDKQEQNAEDWNLYW----RTSSFRMTEHNSVKP 140
K L +++ TP +V+ + G + F ++N +DW W ++ SFR S++
Sbjct: 605 KLLRWKMSTVTPNIVKQTI---GRSHFKISKRN-DDWLGCWGHHMKSPSFR-----SIRE 655
Query: 141 WQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLTFVMPNDYTKFVAEYFQERQ 200
Q+LNH PG+ ++ RKD L ++L M+ +G + F P +F++P D K + + ++
Sbjct: 656 HQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQD-AKLLRKAWES-- 712
Query: 201 MLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQKYISNPLLIGRYKCDLRIYV 260
+ WI KP +RG GI + + +VQ+Y+ P LI K DLRIYV
Sbjct: 713 ---SSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYV 769
Query: 261 CVTGFKPLTIYVYQEGLVRFATEKF--DLSNLQNNYAHLTNSSINKSGASYE-KIKEVIG 317
VT + PL IY++ +GLVRFA+ K+ + +L N + HLTN S+NK A Y+ E+
Sbjct: 770 YVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMAC 829
Query: 318 HGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSV----------PFAANCF 367
G KW L ++YL V+ +W+KI +V+ TI++ P V P+ +C
Sbjct: 830 QGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPY--SCH 887
Query: 368 ELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDL 414
ELFGFDI++D+NLKPW+LEVN SP+L D+ +K +++ D+++L
Sbjct: 888 ELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNL 934
>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
1 [Homo sapiens]
Length = 891
Score = 194 bits (493), Expect = 2e-49
Identities = 133/410 (32%), Positives = 202/410 (49%), Gaps = 46/410 (11%)
Query: 119 EDWNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFI 178
+DW LYW S + +K +Q++NH PG +++ RKD LA+++ M +M+ ++F
Sbjct: 137 DDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKMFPKD-FRFF 195
Query: 179 PLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYI 238
P T+ +P D+ + Y + R K+ +ICKP +G+GI I K+ + I
Sbjct: 196 PRTWCLPADWGD-LQTYSRSR-----KNKTYICKPDSGCQGKGIFITRTVKEIKPGEDMI 249
Query: 239 VQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFD---LSNLQNNYA 295
Q YIS P +I +K DLRIYV VT PL I+VY EGL RFAT + NL +
Sbjct: 250 CQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICM 309
Query: 296 HLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILA 355
HLTN SINK +++ + G K LS F +YL + +W+ I ++I T+++
Sbjct: 310 HLTNYSINKHSSNFSRDAH---SGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLIS 366
Query: 356 IAPSV-----------PFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVK 404
P + + CFE+ GFDIL+D LKPWLLEVN+SP+ + D D VK
Sbjct: 367 AHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVK 426
Query: 405 RKLVHDIIDLIYLNGL---------RNEGREASNATHGNSNIDAAKSDRG-------GLD 448
L++D + LI L R G+ I+ AK R +
Sbjct: 427 DGLLYDTLVLINLESCDKKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYE 486
Query: 449 APDC----LPYDSLSFT--SRMYNEDDSVVEKAVSVRPEAAPASQLEGEM 492
+C L Y SL+ + + +++S+ + V+ R A QL E+
Sbjct: 487 KENCGGFRLIYPSLNSEKYEKFFQDNNSLFQNTVASRAREEYARQLIQEL 536
>gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo
sapiens]
Length = 459
Score = 191 bits (485), Expect = 2e-48
Identities = 124/324 (38%), Positives = 176/324 (54%), Gaps = 28/324 (8%)
Query: 113 KQEQNAEDWNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGT 172
K+ E+W LYW + + +K +Q++NH PG T++ RKD LA++L M ++Y
Sbjct: 110 KEVGEDEEWTLYWTDCAVSLERVMDMKRFQKINHFPGMTEICRKDLLARNLNRMYKLY-P 168
Query: 173 SLYQFIPLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFI 232
S Y P T+ +P DY F + Y ++R K +ICKP +GRGI I + ++
Sbjct: 169 SEYNIFPRTWCLPADYGDFQS-YGRQR-----KARTYICKPDSGCQGRGIFITRNPREIK 222
Query: 233 FDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKF---DLSN 289
+ I Q+YIS PLLI +K D+R+YV +T PL I+ Y+EGL RFAT + +N
Sbjct: 223 PGEHMICQQYISKPLLIDGFKFDMRVYVLITSCDPLRIFTYEEGLARFATTPYMEPSHNN 282
Query: 290 LQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMV 349
L N HLTN +INK ++ + V G K LS +L+ + LW I ++
Sbjct: 283 LDNVCMHLTNYAINKHNENFVRDGAV---GSKRKLSTLNIWLQEHSYNPGELWGDIEDII 339
Query: 350 ILTILAIAPSV---------PFAAN-----CFELFGFDILIDDNLKPWLLEVNYSPALTL 395
I TI++ A SV P N CFE+ GFDIL+D LKPWLLEVN+SP+ T
Sbjct: 340 IKTIIS-AHSVLRHNYRTCFPQYLNGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFTT 398
Query: 396 DCSTDVLVKRKLVHDIIDLIYLNG 419
D D VK L+ D + L+ L G
Sbjct: 399 DSCLDQEVKDALLCDAMTLVNLRG 422
>gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo
sapiens]
Length = 887
Score = 186 bits (473), Expect = 4e-47
Identities = 120/362 (33%), Positives = 190/362 (52%), Gaps = 29/362 (8%)
Query: 98 VVQSVLLERGWNKFDKQEQNAEDWNLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKD 157
+V+ V+ E G+ K +++ + NL W S+ + + + ++ +Q++NH PG ++ RKD
Sbjct: 52 IVRLVIDEMGFMKTPDEDETS---NLIWCDSAVQQEKISELQNYQRINHFPGMGEICRKD 108
Query: 158 CLAKHLKHMRRMYGTSLYQFIPLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELS 217
LA+++ M + Y F+P T++ P +YT+F Y +E + K +I KPA +
Sbjct: 109 FLARNMTKMIKSRPLD-YTFVPRTWIFPAEYTQF-QNYVKELKKK-RKQKTFIVKPANGA 165
Query: 218 RGRGILIFSDFKDFIFDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGL 277
G GI + + D IVQ+YI P L+ YK DLRIY+ VT PL I++Y +GL
Sbjct: 166 MGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGL 225
Query: 278 VRFATEKF---DLSNLQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSW 334
VR TEK+ + SNL Y HLTN S+NK +E+ E G K ++ F +L++
Sbjct: 226 VRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFER-DETENKGSKRSIKWFTEFLQAN 284
Query: 335 DVDDLLLWKKIHRMVILTILAIAPSVPFA-------------ANCFELFGFDILIDDNLK 381
D W I +V+ T++ P V A + CFE+ GFDIL+D LK
Sbjct: 285 QHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLK 344
Query: 382 PWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYL------NGLRNEGREASNATHGNS 435
PWLLE+N +P+ D D VKR ++ + + L+ + L + EA +G +
Sbjct: 345 PWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQKAEAQRRLYGQN 404
Query: 436 NI 437
+I
Sbjct: 405 SI 406
>gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo
sapiens]
Length = 439
Score = 154 bits (389), Expect = 2e-37
Identities = 115/365 (31%), Positives = 175/365 (47%), Gaps = 59/365 (16%)
Query: 90 RVDETTPAVVQSVLLER-GWNKFDKQEQNAEDWNLYWRTSSFRMT--EHNSVKPWQQLNH 146
R T + VL R GW + ++ +W+ YW S+ +H + +++H
Sbjct: 45 RFKTTLMNTLMDVLRHRPGW----VEVKDEGEWDFYWCDVSWLRENFDHTYMDEHVRISH 100
Query: 147 HPGTTKLTRKDCLAKHLKHMRRMYG-------TSLYQFIPLTFVMPNDYTKFVAEYFQER 199
+LTRK+ + K+LK R+ + F P TF MP +Y FV E+ +
Sbjct: 101 FRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPKTFEMPCEYHLFVEEFRKNP 160
Query: 200 QMLGTKHSYWICKPAELSRGRGILIFSDFKDFIF------------DDM----YIVQKYI 243
+ WI KP S+G+GI +F KD + DD+ Y+ Q+YI
Sbjct: 161 GIT------WIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYI 214
Query: 244 SNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSIN 303
NP LIG K DLR+YV L + V+ E L+ + D+ HLTN ++
Sbjct: 215 ENPYLIGGRKFDLRVYV-------LVMSVFAECLLWSGHRRQDV--------HLTNVAVQ 259
Query: 304 KSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLL--LWKKIHRMVILTILAIAPSVP 361
K+ Y K GCKWTL RF YL S + + L++ I + + ++ ++ +
Sbjct: 260 KTSPDYHPKK-----GCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQKVII 314
Query: 362 FAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGLR 421
+CFEL+G+DILID +LKPWLLEVN SP+LT D +K L+ D + ++ + R
Sbjct: 315 SDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEA-R 373
Query: 422 NEGRE 426
GRE
Sbjct: 374 LTGRE 378
>gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo
sapiens]
Length = 800
Score = 138 bits (348), Expect = 1e-32
Identities = 95/298 (31%), Positives = 149/298 (50%), Gaps = 33/298 (11%)
Query: 122 NLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLT 181
++YW SF + S Q+N PG T++ RK L++ ++ M+ ++ Y F P +
Sbjct: 254 DIYWHGVSFHDNDIFS----GQVNKFPGMTEMVRKITLSRAVRTMQNLFPEE-YNFYPRS 308
Query: 182 FVMPNDYTKFVAEYFQERQMLGTKHSYW----ICKPAELSRGRGILIFSDFKDF-----I 232
+++P+++ FVA+ QM+ W I KP +G GI + D D +
Sbjct: 309 WILPDEFQLFVAQV----QMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTL 364
Query: 233 FDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFD---LSN 289
+VQ+YI PLLI + K D+R+YV + PL IY+ ++GL RF TE + N
Sbjct: 365 QSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKN 424
Query: 290 LQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMV 349
L + HLTN S+N ++ + G K T S L S VD +W I +V
Sbjct: 425 LHRIFMHLTNYSLNIHSGNFIH-SDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVV 483
Query: 350 ILTILAIAPSVPF-----------AANCFELFGFDILIDDNLKPWLLEVNYSPALTLD 396
I T++A+ P + CF++ GFDIL+ NLKP LLEVN +P++ ++
Sbjct: 484 IKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIE 541
>gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Homo
sapiens]
Length = 538
Score = 110 bits (276), Expect = 3e-24
Identities = 78/251 (31%), Positives = 124/251 (49%), Gaps = 22/251 (8%)
Query: 122 NLYWRTSSFRMTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLT 181
++YW SF + S Q+N PG T++ RK L++ ++ M+ ++ Y F P +
Sbjct: 254 DIYWHGVSFHDNDIFS----GQVNKFPGMTEMVRKITLSRAVRTMQNLFPEE-YNFYPRS 308
Query: 182 FVMPNDYTKFVAEYFQERQMLGTKHSYW----ICKPAELSRGRGILIFSDFKDF-----I 232
+++P+++ FVA+ QM+ W I KP +G GI + D D +
Sbjct: 309 WILPDEFQLFVAQV----QMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTL 364
Query: 233 FDDMYIVQKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFD---LSN 289
+VQ+YI PLLI + K D+R+YV + PL IY+ ++GL RF TE + N
Sbjct: 365 QSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKN 424
Query: 290 LQNNYAHLTNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMV 349
L + HLTN S+N ++ + G K T S L S VD +W I +V
Sbjct: 425 LHRIFMHLTNYSLNIHSGNFIH-SDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVV 483
Query: 350 ILTILAIAPSV 360
I T++A+ P +
Sbjct: 484 IKTVIALTPEL 494
>gi|24308516 tubulin tyrosine ligase [Homo sapiens]
Length = 377
Score = 105 bits (263), Expect = 9e-23
Identities = 87/286 (30%), Positives = 141/286 (49%), Gaps = 43/286 (15%)
Query: 142 QQLNHHPGTTKLTRKDCLAKHLKHMRRM-------------YGTSLYQFI---------P 179
Q +N++ G KL RK L K +K + Y T+L + P
Sbjct: 60 QLVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPP 119
Query: 180 LTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFK---DFIFDD- 235
++ ++ F+A Y ++++ + + WI K + ++G GILI S+ DFI +
Sbjct: 120 ISNSRTDEREFFLASYNRKKE--DGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQG 177
Query: 236 -MYIVQKYISNPLLI--GRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQN 292
++++QKY+ +PLL+ G K D+R +V V IY+Y+EG++R A+E + + N Q+
Sbjct: 178 QVHVIQKYLEHPLLLEPGHRKFDIRSWVLVD--HQYNIYLYREGVLRTASEPYHVDNFQD 235
Query: 293 NYAHLTNSSINKS-GASYEKIKEVIGHGCKWTLSRFFSYLRS-----WDVDDLLLWKKIH 346
HLTN I K +Y K +E G + F YL S + LL K I
Sbjct: 236 KTCHLTNHCIQKEYSKNYGKYEE----GNEMFFKEFNQYLTSALNITLESSILLQIKHII 291
Query: 347 RMVILTILAIAPSVPFAANCFELFGFDILIDDNLKPWLLEVNYSPA 392
R +L++ + F+LFGFD ++D+ LK WL+EVN +PA
Sbjct: 292 RNCLLSVEPAISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPA 337
>gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo
sapiens]
Length = 772
Score = 104 bits (260), Expect = 2e-22
Identities = 63/198 (31%), Positives = 101/198 (51%), Gaps = 14/198 (7%)
Query: 209 WICKPAELSRGRGILIFSDFKDFIF----------DDMYIVQKYISNPLLIGRYKCDLRI 258
WI KP SRGRGI+ ++ + D ++VQKYI PLLI K DLR
Sbjct: 280 WIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVVQKYIERPLLIFGTKFDLRQ 339
Query: 259 YVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSINKSGASYEKIKEVIGH 318
+ VT + PLT++ Y++ +RF+T+ F L NL N+ HL N+SI K + ++
Sbjct: 340 WFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNS-VHLCNNSIQKHLENSCHRHPLLPP 398
Query: 319 GCKWTLSRFFSYLRSWDVDD---LLLWKKIHRMVILTILAIAPSVPFAANCFELFGFDIL 375
W+ RF ++L+ + ++ + VI + +V FEL+G D +
Sbjct: 399 DNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKASFELYGADFV 458
Query: 376 IDDNLKPWLLEVNYSPAL 393
++ +PWL+E+N SP +
Sbjct: 459 FGEDFQPWLIEINASPTM 476
>gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo
sapiens]
Length = 834
Score = 98.6 bits (244), Expect = 1e-20
Identities = 64/202 (31%), Positives = 104/202 (51%), Gaps = 18/202 (8%)
Query: 209 WICKPAELSRGRGI---LIFSDFKDFIF-----------DDMYIVQKYISNPLLIGRYKC 254
WI KPA SRGRG ++ D + I D+ ++VQKYI PLLI K
Sbjct: 331 WIIKPAAKSRGRGESPDIVCMDRVEEILELAAADHPLSRDNKWVVQKYIETPLLICDTKF 390
Query: 255 DLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSINKSGASYEKIKE 314
D+R + VT + PLTI+ Y+E +RF+T++F L L ++ HL N+++ K +
Sbjct: 391 DIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDKL-DSAIHLCNNAVQKYLKNDVGRSP 449
Query: 315 VIGHGCKWTLSRFFSYLRSWD---VDDLLLWKKIHRMVILTILAIAPSVPFAANCFELFG 371
++ WT +RF YL+ V +++ + + + + V N FEL+G
Sbjct: 450 LLPAHNMWTSTRFQEYLQRQGRGAVWGSVIYPSMKKAIAHAMKVAQDHVEPRKNSFELYG 509
Query: 372 FDILIDDNLKPWLLEVNYSPAL 393
D ++ + +PWL+E+N SP +
Sbjct: 510 ADFVLGRDFRPWLIEINSSPTM 531
>gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform
1 [Homo sapiens]
Length = 673
Score = 92.0 bits (227), Expect = 1e-18
Identities = 99/418 (23%), Positives = 160/418 (38%), Gaps = 91/418 (21%)
Query: 79 PSGALLKPLVFRVDETTP-----------------AVVQSVLLERGWNKFDKQEQNAEDW 121
PS ALL+ L+ + +P ++ S +GW + + +D+
Sbjct: 133 PSAALLEGLLLGGGKPSPHSTRPGPFFYIGGSNGATIISSYCKSKGWQRI--HDSRRDDY 190
Query: 122 NLYWRTSSFRMTEHNSVKPWQQLNHH-PGTTKLTRKDCLAKHLKHMRRMYGTS------- 173
L W R + S + +QL + P LT K L L+ R +
Sbjct: 191 TLKWCEVKSR-DSYGSFREGEQLLYQLPNNKLLTTKIGLLSTLRGRARAMSKASKVPGGV 249
Query: 174 -----------LYQFIPLT---FVMPNDYTKFVAEYFQERQMLGTKHS------------ 207
+ +P T ++ P + + E+F E L KH
Sbjct: 250 QARLEKDAAAPALEDLPWTSPGYLRPQRVLR-MEEFFPETYRLDLKHEREAFFTLFDETQ 308
Query: 208 YWICKPAELSRGRGILIFSDFKD---------------------FIFDDMYIVQKYISNP 246
WICKP ++G+GI + + ++ F +VQ+YI NP
Sbjct: 309 IWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNP 368
Query: 247 LLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSINKSG 306
LL+ K D+R Y+ + P I+ + G R +D + + HLTN + K
Sbjct: 369 LLVDGRKFDVRSYLLIACTTPYMIF-FGHGYARLTLSLYD-PHSSDLGGHLTNQFMQKKS 426
Query: 307 ASYEKIKEVIGHGCKWTLSRFFSYLRS--WDVDDLL-------LWKKIHRMVILTILAIA 357
Y +KE W++ Y+ W L L K++ +++ LA
Sbjct: 427 PLYMLLKE----HTVWSMEHLNRYISDTFWKARGLAKDWVFTTLKKRMQQIMAHCFLAAK 482
Query: 358 PSVPFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLI 415
P + F+L G D LIDDN K WLLE+N +PAL +C V +V + +DL+
Sbjct: 483 PKLDCKLGYFDLIGCDFLIDDNFKVWLLEMNSNPALHTNCEVLKEVIPGVVIETLDLV 540
>gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo
sapiens]
Length = 644
Score = 78.2 bits (191), Expect = 2e-14
Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 14/192 (7%)
Query: 116 QNAEDWNLYWRTSSFR-MTEHNSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSL 174
Q+ D ++ + S F+ + + +P LN P LT KDCLA RR G
Sbjct: 327 QSEADADILFNFSHFKDYRKLSQERPGVLLNQFPCENLLTVKDCLASIA---RRAGGPEG 383
Query: 175 YQFIPLTFVMPNDYTKFVAEYFQERQMLGTKHSYWICKPAELSRGRGILIFSDFKDFIF- 233
++P TF + + +FV+ YFQ+R+ G + ++WICKP L+R + I
Sbjct: 384 PPWLPRTFNLRTELPQFVS-YFQQRERWG-EDNHWICKPWNLARSLDTHVTKSLHSIIRH 441
Query: 234 --DDMYIVQKYISNPLL-----IGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFD 286
+V KYI +P+L +G+ K D+R V + +PL ++VY +RF+ F
Sbjct: 442 RESTPKVVSKYIESPVLFLREDVGKVKFDIRYIVLLRSVRPLRLFVYDVFWLRFSNRAFA 501
Query: 287 LSNLQNNYAHLT 298
L++L + H T
Sbjct: 502 LNDLDDYEKHFT 513
>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
2 [Homo sapiens]
Length = 584
Score = 72.4 bits (176), Expect = 1e-12
Identities = 57/202 (28%), Positives = 90/202 (44%), Gaps = 33/202 (16%)
Query: 324 LSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSV-----------PFAANCFELFGF 372
LS F +YL + +W+ I ++I T+++ P + + CFE+ GF
Sbjct: 28 LSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEILGF 87
Query: 373 DILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLIYLNGL---------RNE 423
DIL+D LKPWLLEVN+SP+ + D D VK L++D + LI L R
Sbjct: 88 DILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLINLESCDKKKVLEEERQR 147
Query: 424 GREASNATHGNSNIDAAKSDRG-------GLDAPDC----LPYDSLSFT--SRMYNEDDS 470
G+ I+ AK R + +C L Y SL+ + + +++S
Sbjct: 148 GQFLQQCCSREMRIEEAKGFRAVQLKKTETYEKENCGGFRLIYPSLNSEKYEKFFQDNNS 207
Query: 471 VVEKAVSVRPEAAPASQLEGEM 492
+ + V+ R A QL E+
Sbjct: 208 LFQNTVASRAREEYARQLIQEL 229
>gi|194239678 tubulin tyrosine ligase-like family, member 10 isoform
2 [Homo sapiens]
Length = 404
Score = 53.9 bits (128), Expect = 4e-07
Identities = 75/357 (21%), Positives = 126/357 (35%), Gaps = 90/357 (25%)
Query: 79 PSGALLKPLVFRVDETTP-----------------AVVQSVLLERGWNKFDKQEQNAEDW 121
PS ALL+ L+ + +P ++ S +GW + + +D+
Sbjct: 60 PSAALLEGLLLGGGKPSPHSTRPGPFFYIGGSNGATIISSYCKSKGWQRI--HDSRRDDY 117
Query: 122 NLYWRTSSFRMTEHNSVKPWQQLNHH-PGTTKLTRKDCLAKHLKHMRRMYGTS------- 173
L W R + S + +QL + P LT K L L+ R +
Sbjct: 118 TLKWCEVKSR-DSYGSFREGEQLLYQLPNNKLLTTKIGLLSTLRGRARAMSKASKVPGGV 176
Query: 174 -----------LYQFIPLT---FVMPNDYTKFVAEYFQERQMLGTKHS------------ 207
+ +P T ++ P + + E+F E L KH
Sbjct: 177 QARLEKDAAAPALEDLPWTSPGYLRPQRVLR-MEEFFPETYRLDLKHEREAFFTLFDETQ 235
Query: 208 YWICKPAELSRGRGILIFSDFKD---------------------FIFDDMYIVQKYISNP 246
WICKP ++G+GI + + ++ F +VQ+YI NP
Sbjct: 236 IWICKPTASNQGKGIFLLRNQEEVAALQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNP 295
Query: 247 LLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSINKSG 306
LL+ K D+R Y+ + P I+ + G R +D + + HLTN + K
Sbjct: 296 LLVDGRKFDVRSYLLIACTTPYMIF-FGHGYARLTLSLYD-PHSSDLGGHLTNQFMQKKS 353
Query: 307 ASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLLLWKK--IHRMVILTILAIAPSVP 361
Y +KE W++ Y+ WK + + + T L + P P
Sbjct: 354 PLYMLLKE----HTVWSMEHLNRYISD------TFWKARGLAKDWVFTTLKVRPLCP 400
>gi|130502140 NEZHA isoform 2 [Homo sapiens]
Length = 1249
Score = 39.3 bits (90), Expect = 0.010
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 9/95 (9%)
Query: 468 DDSVVEKAVSVRPEAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPY--- 524
D +E+A+ + A P +G G F+L + E P SKP L S + P T P
Sbjct: 455 DLPTIEEALQIIHSAEPRLLPDGAADGS-FYLHSPEGP-SKPSLASPYLPEGTSKPLSDR 512
Query: 525 ---ASLFQSH-SCKTKTSPCVLSDRGKAPDPQAGN 555
A ++ H +K SPC++ + K P P G+
Sbjct: 513 PTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGS 547
>gi|122937255 NEZHA isoform 1 [Homo sapiens]
Length = 1276
Score = 39.3 bits (90), Expect = 0.010
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 9/95 (9%)
Query: 468 DDSVVEKAVSVRPEAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPY--- 524
D +E+A+ + A P +G G F+L + E P SKP L S + P T P
Sbjct: 482 DLPTIEEALQIIHSAEPRLLPDGAADGS-FYLHSPEGP-SKPSLASPYLPEGTSKPLSDR 539
Query: 525 ---ASLFQSH-SCKTKTSPCVLSDRGKAPDPQAGN 555
A ++ H +K SPC++ + K P P G+
Sbjct: 540 PTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGS 574
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 32.7 bits (73), Expect = 0.96
Identities = 18/64 (28%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 45 ARLQEAGVSIPPRRGRPTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTPAVVQSVLL 104
A+++ GVS PP+ P E +++PH ++E G L++ ++ + P+ + +L
Sbjct: 785 AQVEIRGVSHPPQIVLPIHNWEPEEEPH---KEEEVGPLVEH-IYELHNIGPSTISDTIL 840
Query: 105 ERGW 108
E GW
Sbjct: 841 EVGW 844
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 32.3 bits (72), Expect = 1.3
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 12/73 (16%)
Query: 483 APASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPCVL 542
+P +Q++ E + Q +LS+R P++ ++S +P + L P +KTSP L
Sbjct: 424 SPVTQVKDEAAAQPLNLSSR--PKTAEPVKSPTSPTQNLFP----------ASKTSPVNL 471
Query: 543 SDRGKAPDPQAGN 555
++ P P G+
Sbjct: 472 PNKSSIPSPIGGS 484
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 32.3 bits (72), Expect = 1.3
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 12/73 (16%)
Query: 483 APASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPCVL 542
+P +Q++ E + Q +LS+R P++ ++S +P + L P +KTSP L
Sbjct: 370 SPVTQVKDEAAAQPLNLSSR--PKTAEPVKSPTSPTQNLFP----------ASKTSPVNL 417
Query: 543 SDRGKAPDPQAGN 555
++ P P G+
Sbjct: 418 PNKSSIPSPIGGS 430
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 32.3 bits (72), Expect = 1.3
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 12/73 (16%)
Query: 483 APASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPCVL 542
+P +Q++ E + Q +LS+R P++ ++S +P + L P +KTSP L
Sbjct: 373 SPVTQVKDEAAAQPLNLSSR--PKTAEPVKSPTSPTQNLFP----------ASKTSPVNL 420
Query: 543 SDRGKAPDPQAGN 555
++ P P G+
Sbjct: 421 PNKSSIPSPIGGS 433
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 32.3 bits (72), Expect = 1.3
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 12/73 (16%)
Query: 483 APASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHSCKTKTSPCVL 542
+P +Q++ E + Q +LS+R P++ ++S +P + L P +KTSP L
Sbjct: 411 SPVTQVKDEAAAQPLNLSSR--PKTAEPVKSPTSPTQNLFP----------ASKTSPVNL 458
Query: 543 SDRGKAPDPQAGN 555
++ P P G+
Sbjct: 459 PNKSSIPSPIGGS 471
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 32.0 bits (71), Expect = 1.6
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 7/67 (10%)
Query: 37 EQPPAGLGARLQEAGVSIPPRRGRPTPTLEKKKKPHLMAEDEPSGAL----LKPLVFRVD 92
E+PP A++ EA I P + P P +K+K P +EP + + P V +++
Sbjct: 9573 EEPPP---AKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKME 9629
Query: 93 ETTPAVV 99
E PA V
Sbjct: 9630 EPLPAKV 9636
>gi|11560152 zinc finger protein 335 [Homo sapiens]
Length = 1342
Score = 31.6 bits (70), Expect = 2.1
Identities = 22/58 (37%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Query: 31 SEANHTEQPPAGLGARLQEAGVSIPPRRGRPTPTLEKKKKPHLMAEDEPSGALLKPLV 88
S+ N E P G RLQ S P R RP +K P L D P G +PLV
Sbjct: 321 SDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPG---RPRKLPRLEISDLPDGVEGEPLV 375
>gi|169167201 PREDICTED: hypothetical protein [Homo sapiens]
Length = 145
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 473 EKAVSVRPEAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHS 532
E+A PEA + L+ +++ D +S+ +P ++PKLR R + L YA+
Sbjct: 3 ERAGGKNPEAPDTAPLDEKLASSDDSISSA-IPPTRPKLRRRKGDTERLTDYATARARAQ 61
Query: 533 CKTKTSPCVLSDRGKAPDPQA 553
+ + S R AP A
Sbjct: 62 PASSAAQLPRSHRPPAPSAPA 82
>gi|169166894 PREDICTED: hypothetical protein [Homo sapiens]
Length = 145
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 473 EKAVSVRPEAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHS 532
E+A PEA + L+ +++ D +S+ +P ++PKLR R + L YA+
Sbjct: 3 ERAGGKNPEAPDTAPLDEKLASSDDSISSA-IPPTRPKLRRRKGDTERLRDYATARARAQ 61
Query: 533 CKTKTSPCVLSDRGKAPDPQA 553
+ + S R AP A
Sbjct: 62 PASSAAQLPRSHRPPAPSAPA 82
>gi|169166324 PREDICTED: hypothetical protein [Homo sapiens]
Length = 145
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 473 EKAVSVRPEAAPASQLEGEMSGQDFHLSTREMPQSKPKLRSRHTPHKTLMPYASLFQSHS 532
E+A PEA + L+ +++ D +S+ +P ++PKLR R + L YA+
Sbjct: 3 ERAGGKNPEAPDTAPLDEKLASSDDSISSA-IPPTRPKLRRRKGDTERLRDYATARARAQ 61
Query: 533 CKTKTSPCVLSDRGKAPDPQA 553
+ + S R AP A
Sbjct: 62 PASSAAQLPRSHRPPAPSAPA 82
>gi|239750706 PREDICTED: hypothetical protein XP_002347489 [Homo
sapiens]
Length = 133
Score = 30.4 bits (67), Expect = 4.8
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 7/60 (11%)
Query: 37 EQPPAGLGARLQEAGVSIPPRRGRPTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTP 96
++ A +G RL+EA + IPP P+ +K HL GA+L PL + E P
Sbjct: 59 QEQDAHVGPRLEEAWIQIPP---VPSTRRARKAISHL----RKPGAVLSPLTCELQEKLP 111
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,467,724
Number of Sequences: 37866
Number of extensions: 1104685
Number of successful extensions: 3098
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 3016
Number of HSP's gapped (non-prelim): 56
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.