Guide to the Human Genome
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Name: CDKN2A Sequence: fasta or formatted (116aa) NCBI GI: 98985804
Description:

cyclin-dependent kinase inhibitor 2A isoform 3

Referenced in:

Cyclins and Related Functions
p53 Pathway

Other entries for this name:
alt prot [173aa] cyclin-dependent kinase inhibitor 2A isoform 4
alt prot [156aa] cyclin-dependent kinase inhibitor 2A isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            16.4         19           3
 C cysteine            0.9          1           1
 D aspartate           2.6          3           1
 E glutamate          11.2         13           3
 F phenylalanine       1.7          2           1
 G glycine            14.7         17           2
 H histidine           0.9          1           1
 I isoleucine          1.7          2           1
 K lysine              3.4          4           2
 L leucine             7.8          9           2
 M methionine          1.7          2           1
 N asparagine          2.6          3           1
 P proline             7.8          9           3
 Q glutamine           0.9          1           1
 R arginine            9.5         11           2
 S serine              7.8          9           2
 T threonine           1.7          2           1
 V valine              3.4          4           1
 W tryptophan          2.6          3           1
 Y tyrosine            0.9          1           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cyclin-dependent kinase inhibitor 2A isoform 3 [Homo... 
CDKN2A                0.366   cyclin-dependent kinase inhibitor 2A isoform 1 
CDKN2B                0.122   cyclin-dependent kinase inhibitor 2B isoform 2 [Homo...
CDKN2B                0.122   cyclin-dependent kinase inhibitor 2B isoform 1 [Homo...
CDKN2C                0.061   cyclin-dependent kinase inhibitor 2C 
CDKN2C                0.061   cyclin-dependent kinase inhibitor 2C 
TJP3                  0.042   tight junction protein 3 
ASB15                 0.038   ankyrin repeat and SOCS box-containing 15 
CDKN2D                0.038   cyclin-dependent kinase inhibitor 2D 
CDKN2D                0.038   cyclin-dependent kinase inhibitor 2D 
ANKZF1                0.038   ankyrin repeat and zinc finger domain containing 1 ...
ANKZF1                0.038   ankyrin repeat and zinc finger domain containing 1 ...
ANKRD28               0.038   ankyrin repeat domain 28 
ANKFY1                0.033   ankyrin repeat and FYVE domain containing 1 isoform...
ANKRD52               0.033   ankyrin repeat domain 52 
ZCCHC3                0.033   zinc finger, CCHC domain containing 3 
LRCH3                 0.033   leucine-rich repeats and calponin homology (CH) doma...
NOTCH4                0.033   notch4 preproprotein 
ANKRD50               0.033   ankyrin repeat domain 50 
LOC100128960          0.028   PREDICTED: similar to paraneoplastic antigen MA2 [H...
LOC100128960          0.028   PREDICTED: similar to Putative paraneoplastic antig...
ASB10                 0.028   ankyrin repeat and SOCS box-containing 10 isoform 2...
ASB10                 0.028   ankyrin repeat and SOCS box-containing 10 isoform 1...
ASB10                 0.028   ankyrin repeat and SOCS box-containing 10 isoform 3...
TANC2                 0.028   tetratricopeptide repeat, ankyrin repeat and coiled...
GNAS                  0.028   GNAS complex locus XLas 
LOC100292528          0.028   PREDICTED: similar to hCG2029702 
LOC100291372          0.028   PREDICTED: hypothetical protein XP_002346846 
LOC100289495          0.028   PREDICTED: hypothetical protein XP_002342696 
ANKFY1                0.023   ankyrin repeat and FYVE domain containing 1 isoform ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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