Guide to the Human Genome
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Search of human proteins with 93102424

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|93102424 hypothetical protein LOC23116 [Homo sapiens]
         (1720 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|93102424 hypothetical protein LOC23116 [Homo sapiens]             3377   0.0  
gi|145587088 hypothetical protein LOC165186 [Homo sapiens]            332   2e-90
gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens]       62   5e-09
gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens]       62   5e-09
gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens]        62   5e-09
gi|57863301 CLIP-associating protein 2 [Homo sapiens]                  61   8e-09
gi|83367077 mucin 16 [Homo sapiens]                                    50   1e-05
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        46   3e-04
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    45   8e-04
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           44   0.002
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           44   0.002
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    43   0.002
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun...    42   0.004
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun...    42   0.004
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit...    42   0.004
gi|31543559 radial spoke 3 homolog [Homo sapiens]                      42   0.005
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    42   0.007
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]                    42   0.007
gi|209863002 MAP-kinase activating death domain-containing prote...    41   0.009
gi|209862998 MAP-kinase activating death domain-containing prote...    41   0.009
gi|209862987 MAP-kinase activating death domain-containing prote...    41   0.009
gi|209862979 MAP-kinase activating death domain-containing prote...    41   0.009
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             41   0.009
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        40   0.015
gi|209862971 MAP-kinase activating death domain-containing prote...    40   0.020
gi|209571517 MAP-kinase activating death domain-containing prote...    40   0.020
gi|33667044 ABI gene family, member 3 (NESH) binding protein [Ho...    40   0.020
gi|122937243 dual specificity phosphatase 27 [Homo sapiens]            39   0.044
gi|161016767 mucin 21 [Homo sapiens]                                   39   0.044
gi|20070205 ladinin 1 [Homo sapiens]                                   39   0.044

>gi|93102424 hypothetical protein LOC23116 [Homo sapiens]
          Length = 1720

 Score = 3377 bits (8755), Expect = 0.0
 Identities = 1720/1720 (100%), Positives = 1720/1720 (100%)

Query: 1    MAAAPSALLLLPPFPVLSTYRLQSRSRPSAPETDDSRVGGIMRGEKNYYFRGAAGDHGSC 60
            MAAAPSALLLLPPFPVLSTYRLQSRSRPSAPETDDSRVGGIMRGEKNYYFRGAAGDHGSC
Sbjct: 1    MAAAPSALLLLPPFPVLSTYRLQSRSRPSAPETDDSRVGGIMRGEKNYYFRGAAGDHGSC 60

Query: 61   PTTTSPLASALLMPSEAVSSSWSESGGGLSGGDEEDTRLLQLLRTARDPSEAFQALQAAL 120
            PTTTSPLASALLMPSEAVSSSWSESGGGLSGGDEEDTRLLQLLRTARDPSEAFQALQAAL
Sbjct: 61   PTTTSPLASALLMPSEAVSSSWSESGGGLSGGDEEDTRLLQLLRTARDPSEAFQALQAAL 120

Query: 121  PRRGGRLGFPRRKEALYRALGRVLVEGGSDEKRLCLQLLSDVLRGQGEAGQLEEAFSLAL 180
            PRRGGRLGFPRRKEALYRALGRVLVEGGSDEKRLCLQLLSDVLRGQGEAGQLEEAFSLAL
Sbjct: 121  PRRGGRLGFPRRKEALYRALGRVLVEGGSDEKRLCLQLLSDVLRGQGEAGQLEEAFSLAL 180

Query: 181  LPQLVVSLREENPALRKDALQILHICLKRSPGEVLRTLIQQGLESTDARLRASTALLLPI 240
            LPQLVVSLREENPALRKDALQILHICLKRSPGEVLRTLIQQGLESTDARLRASTALLLPI
Sbjct: 181  LPQLVVSLREENPALRKDALQILHICLKRSPGEVLRTLIQQGLESTDARLRASTALLLPI 240

Query: 241  LLTTEDLLLGLDLTEVIISLARKLGDQETEEESETAFSALQQIGERLGQDRFQSYISRLP 300
            LLTTEDLLLGLDLTEVIISLARKLGDQETEEESETAFSALQQIGERLGQDRFQSYISRLP
Sbjct: 241  LLTTEDLLLGLDLTEVIISLARKLGDQETEEESETAFSALQQIGERLGQDRFQSYISRLP 300

Query: 301  SALRRHYNRRLESQFGSQVPYYLELEASGFPEDPLPCAVTLSNSNLKFGIIPQELHSRLL 360
            SALRRHYNRRLESQFGSQVPYYLELEASGFPEDPLPCAVTLSNSNLKFGIIPQELHSRLL
Sbjct: 301  SALRRHYNRRLESQFGSQVPYYLELEASGFPEDPLPCAVTLSNSNLKFGIIPQELHSRLL 360

Query: 361  DQEDYKNRTQAVEELKQVLGKFNPSSTPHSSLVGFISLLYNLLDDSNFKVVHGTLEVLHL 420
            DQEDYKNRTQAVEELKQVLGKFNPSSTPHSSLVGFISLLYNLLDDSNFKVVHGTLEVLHL
Sbjct: 361  DQEDYKNRTQAVEELKQVLGKFNPSSTPHSSLVGFISLLYNLLDDSNFKVVHGTLEVLHL 420

Query: 421  LVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKEVGPQQVLCLLLEHLK 480
            LVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKEVGPQQVLCLLLEHLK
Sbjct: 421  LVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKEVGPQQVLCLLLEHLK 480

Query: 481  HKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAFAVLASS 540
            HKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAFAVLASS
Sbjct: 481  HKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAFAVLASS 540

Query: 541  MGSGKTSILFKAVDTVELQDNGDGVMNAVQARLARKTLPRLTEQGFVEYAVLMPSSAGGR 600
            MGSGKTSILFKAVDTVELQDNGDGVMNAVQARLARKTLPRLTEQGFVEYAVLMPSSAGGR
Sbjct: 541  MGSGKTSILFKAVDTVELQDNGDGVMNAVQARLARKTLPRLTEQGFVEYAVLMPSSAGGR 600

Query: 601  SNHLAHGADTDWLLAGNRTQSAHCHCGDHVRDSMHIYGSYSPTICTRRVLSAGKGKNKLP 660
            SNHLAHGADTDWLLAGNRTQSAHCHCGDHVRDSMHIYGSYSPTICTRRVLSAGKGKNKLP
Sbjct: 601  SNHLAHGADTDWLLAGNRTQSAHCHCGDHVRDSMHIYGSYSPTICTRRVLSAGKGKNKLP 660

Query: 661  WENEQPGIMGENQTSTSKDIEQFSTYDFIPSAKLKLSQGMPVNDDLCFSRKRVSRNLFQN 720
            WENEQPGIMGENQTSTSKDIEQFSTYDFIPSAKLKLSQGMPVNDDLCFSRKRVSRNLFQN
Sbjct: 661  WENEQPGIMGENQTSTSKDIEQFSTYDFIPSAKLKLSQGMPVNDDLCFSRKRVSRNLFQN 720

Query: 721  SRDFNPDCLPLCAAGTTGTHQTNLSGKCAQLGFSQICGKTGSVGSDLQFLGTTSSHQEKV 780
            SRDFNPDCLPLCAAGTTGTHQTNLSGKCAQLGFSQICGKTGSVGSDLQFLGTTSSHQEKV
Sbjct: 721  SRDFNPDCLPLCAAGTTGTHQTNLSGKCAQLGFSQICGKTGSVGSDLQFLGTTSSHQEKV 780

Query: 781  YASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSPLIISPKKS 840
            YASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSPLIISPKKS
Sbjct: 781  YASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSPLIISPKKS 840

Query: 841  QDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRS 900
            QDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRS
Sbjct: 841  QDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRS 900

Query: 901  PSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFK 960
            PSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFK
Sbjct: 901  PSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFK 960

Query: 961  DKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINS 1020
            DKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINS
Sbjct: 961  DKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINS 1020

Query: 1021 YSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSPSAG 1080
            YSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSPSAG
Sbjct: 1021 YSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSPSAG 1080

Query: 1081 SSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLSSAPATCSQSVISSVENGDTFSIKQ 1140
            SSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLSSAPATCSQSVISSVENGDTFSIKQ
Sbjct: 1081 SSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLSSAPATCSQSVISSVENGDTFSIKQ 1140

Query: 1141 SIEPPSGIYGRSVQQNISSYLDVENEKDAKVSISKSTYNKMRQKRKEEKELFHNKDCEKK 1200
            SIEPPSGIYGRSVQQNISSYLDVENEKDAKVSISKSTYNKMRQKRKEEKELFHNKDCEKK
Sbjct: 1141 SIEPPSGIYGRSVQQNISSYLDVENEKDAKVSISKSTYNKMRQKRKEEKELFHNKDCEKK 1200

Query: 1201 EKNSWERMRHTGTEKMASESETPTGAISQYKERMPSVTHSPEIMDLSELRPFSKPEIALT 1260
            EKNSWERMRHTGTEKMASESETPTGAISQYKERMPSVTHSPEIMDLSELRPFSKPEIALT
Sbjct: 1201 EKNSWERMRHTGTEKMASESETPTGAISQYKERMPSVTHSPEIMDLSELRPFSKPEIALT 1260

Query: 1261 EALRLLADEDWEKKIEGLNFIRCLAAFHSEILNTKLHETNFAVVQEVKNLRSGVSRAAVV 1320
            EALRLLADEDWEKKIEGLNFIRCLAAFHSEILNTKLHETNFAVVQEVKNLRSGVSRAAVV
Sbjct: 1261 EALRLLADEDWEKKIEGLNFIRCLAAFHSEILNTKLHETNFAVVQEVKNLRSGVSRAAVV 1320

Query: 1321 CLSDLFTYLKKSMDQELDTTVKVLLHKAGESNTFIREDVDKALRAMVNNVTPARAVVSLI 1380
            CLSDLFTYLKKSMDQELDTTVKVLLHKAGESNTFIREDVDKALRAMVNNVTPARAVVSLI
Sbjct: 1321 CLSDLFTYLKKSMDQELDTTVKVLLHKAGESNTFIREDVDKALRAMVNNVTPARAVVSLI 1380

Query: 1381 NGGQRYYGRKMLFFMMCHPNFEKMLEKYVPSKDLPYIKDSVRNLQQKGLGEIPLDTPSAK 1440
            NGGQRYYGRKMLFFMMCHPNFEKMLEKYVPSKDLPYIKDSVRNLQQKGLGEIPLDTPSAK
Sbjct: 1381 NGGQRYYGRKMLFFMMCHPNFEKMLEKYVPSKDLPYIKDSVRNLQQKGLGEIPLDTPSAK 1440

Query: 1441 GRRSHTGSVGNTRSSSVSRDAFNSAERAVTEVREVTRKSVPRNSLESAEYLKLITGLLNA 1500
            GRRSHTGSVGNTRSSSVSRDAFNSAERAVTEVREVTRKSVPRNSLESAEYLKLITGLLNA
Sbjct: 1441 GRRSHTGSVGNTRSSSVSRDAFNSAERAVTEVREVTRKSVPRNSLESAEYLKLITGLLNA 1500

Query: 1501 KDFRDRINGIKQLLSDTENNQDLVVGNIVKIFDAFKSRLHDSNSKVNLVALETMHKMIPL 1560
            KDFRDRINGIKQLLSDTENNQDLVVGNIVKIFDAFKSRLHDSNSKVNLVALETMHKMIPL
Sbjct: 1501 KDFRDRINGIKQLLSDTENNQDLVVGNIVKIFDAFKSRLHDSNSKVNLVALETMHKMIPL 1560

Query: 1561 LRDHLSPIINMLIPAIVDNNLNSKNPGIYAAATNVVQALSQHVDNYLLLQPFCTKAQFLN 1620
            LRDHLSPIINMLIPAIVDNNLNSKNPGIYAAATNVVQALSQHVDNYLLLQPFCTKAQFLN
Sbjct: 1561 LRDHLSPIINMLIPAIVDNNLNSKNPGIYAAATNVVQALSQHVDNYLLLQPFCTKAQFLN 1620

Query: 1621 GKAKQDMTEKLADIVTELYQRKPHATEQKVLVVLWHLLGNMTNSGSLPGAGGNIRTATAK 1680
            GKAKQDMTEKLADIVTELYQRKPHATEQKVLVVLWHLLGNMTNSGSLPGAGGNIRTATAK
Sbjct: 1621 GKAKQDMTEKLADIVTELYQRKPHATEQKVLVVLWHLLGNMTNSGSLPGAGGNIRTATAK 1680

Query: 1681 LSKALFAQMGQNLLNQAASQPPHIKKSLEELLDMTILNEL 1720
            LSKALFAQMGQNLLNQAASQPPHIKKSLEELLDMTILNEL
Sbjct: 1681 LSKALFAQMGQNLLNQAASQPPHIKKSLEELLDMTILNEL 1720


>gi|145587088 hypothetical protein LOC165186 [Homo sapiens]
          Length = 1019

 Score =  332 bits (851), Expect = 2e-90
 Identities = 237/651 (36%), Positives = 333/651 (51%), Gaps = 119/651 (18%)

Query: 1170 KVSISKSTYNKMRQKRKEEKELFHNKD-----------CEKKEKNSWER----MRHTGT- 1213
            +V+ISKS   KM+ K+ +E EL    +           C   ++   +     +R +GT 
Sbjct: 350  QVTISKSAREKMQLKQMKEMELLRRLEEPRTGQELTSQCLGSQRAFMKEGLLPLRGSGTL 409

Query: 1214 ------------------EKMASESETPTGAISQYKER---------MPSVT-------H 1239
                               K AS +  P+  IS+ + R         +P+V         
Sbjct: 410  SVPTRLSGPCRNDVSIILRKWASRASLPSIPISRQEPRFARHASANSLPAVLTLGSPEWE 469

Query: 1240 SPEIMDL---SELRPFSKPEIALTEALRLLADEDWEKKIEGLNFIRCLAAFHSEILNTKL 1296
              E MDL    ELRPFS PE+ L +AL+ L   DW+ K +GL  I+ LAA HSE+L  KL
Sbjct: 470  EEEEMDLRACKELRPFSNPELGLRDALQCLNSSDWQMKEKGLVSIQRLAACHSEVLTGKL 529

Query: 1297 HETNFAVVQEVKNLRSGVSRAAVVCLSDLFTYLKKSMDQELDTTVKVLLHKAGESNTFIR 1356
            H+    V  EV NLRS VS  A+  L DLF  LKK+MDQE +   + LL K  ++N FI+
Sbjct: 530  HDVCLVVTGEVTNLRSKVSHLAISTLGDLFQALKKNMDQEAEEIARCLLQKMADTNEFIQ 589

Query: 1357 EDVDKALRAMVNNVTPAR--------------------------AVVSLI---------- 1380
                ++LRAMV NVT AR                          AV+  I          
Sbjct: 590  RAAGQSLRAMVENVTLARSLVVLTSAGVYHRNPLIRKYAAEHLSAVLEQIGAEKLLSGTR 649

Query: 1381 -----------------NGGQRYYGRKMLFFMMCHPNFEKMLEKYVPSKDLPYIKDSVRN 1423
                             N   R+YGRKM+  +M +  F+  L++ +PS DL  +  +++ 
Sbjct: 650  DSTDMLVHNLVRLAQDSNQDTRFYGRKMVNILMANTKFDAFLKQSLPSYDLQKVMAAIK- 708

Query: 1424 LQQKGLGEIPLDTPSAKGRRSHTGSVGNTRSSSVSRDAFNSAER-AVTEVREVTRKSVPR 1482
              Q+G+ +   + PSAKGR+         RS  V  +     E  +    R V  +S  +
Sbjct: 709  --QQGIEDND-ELPSAKGRKV-------LRSLVVCENGLPIKEGLSCNGPRLVGLRSTLQ 758

Query: 1483 NSLESAEYLKLITGLLNAKDFRDRINGIKQLLSDTENNQDLVVGNIVKIFDAFKSRLHDS 1542
               E  E L+ +T LL AKDFR R+ G+ QLL   +   +LV  ++V++FDAF  RL DS
Sbjct: 759  GRGEMVEQLRELTRLLEAKDFRSRMEGVGQLLELCKAKTELVTAHLVQVFDAFTPRLQDS 818

Query: 1543 NSKVNLVALETMHKMIPLLRDHLSPIINMLIPAIVDNNLNSKNPGIYAAATNVVQALSQH 1602
            N KVN  ALE+  KMIPLLR+ L P++  +I  + DN LNSKN GIYAAA  V+ A+ + 
Sbjct: 819  NKKVNQWALESFAKMIPLLRESLHPMLLSIIITVADN-LNSKNSGIYAAAVAVLDAMVES 877

Query: 1603 VDNYLLLQPFCTKAQFLNGKAKQDMTEKLADIVTELYQRKPHATEQKVLVVLWHLLGNMT 1662
            +DN  LL     + +FL+G+A  D+T++LA +V  +Y RKP A E+ VL +LWH L   T
Sbjct: 878  LDNLCLLPALAGRVRFLSGRAVLDVTDRLAVLVASVYPRKPQAVERHVLPILWHFLNTAT 937

Query: 1663 NSGSLPGAGGNIRTATAKLSKALFAQMGQNLLNQAASQPPHIKKSLEELLD 1713
             +G+LPG  GNIR    +LS++L   MG  LL+ AASQP H+ K+L+ELLD
Sbjct: 938  RNGTLPGPSGNIRGVVCRLSRSLQEHMGSRLLDFAASQPKHVLKTLQELLD 988



 Score = 35.4 bits (80), Expect = 0.48
 Identities = 80/338 (23%), Positives = 139/338 (41%), Gaps = 66/338 (19%)

Query: 136 LYRALGRVLVEGGSDEKRLCLQLLSDVLRG-QGEAGQLEEAF--SLALLPQLVV----SL 188
           L++AL + + +   +  R  LQ ++D     Q  AGQ   A   ++ L   LVV     +
Sbjct: 558 LFQALKKNMDQEAEEIARCLLQKMADTNEFIQRAAGQSLRAMVENVTLARSLVVLTSAGV 617

Query: 189 REENPALRKDALQILHICLKRSPGEVLRTLIQQGLESTDARLRASTALLLPILLTTEDLL 248
              NP +RK A + L   L+           Q G E   +  R ST +L+  L       
Sbjct: 618 YHRNPLIRKYAAEHLSAVLE-----------QIGAEKLLSGTRDSTDMLVHNL------- 659

Query: 249 LGLDLTEVIISLARKLGDQETEEESETAFSALQQIGERLGQDRFQSYISR-LPS------ 301
                    + LA+       +   +T F   + +   +   +F +++ + LPS      
Sbjct: 660 ---------VRLAQ-------DSNQDTRFYGRKMVNILMANTKFDAFLKQSLPSYDLQKV 703

Query: 302 --ALRRHY---NRRLESQFGSQVPYYLELEASGFP-EDPLPC----AVTLSNSNLKFGII 351
             A+++     N  L S  G +V   L +  +G P ++ L C     V L ++    G +
Sbjct: 704 MAAIKQQGIEDNDELPSAKGRKVLRSLVVCENGLPIKEGLSCNGPRLVGLRSTLQGRGEM 763

Query: 352 PQELH--SRLLDQEDYKNRTQAVEELKQVLGKFNPSSTPHSSLVGFISLLYNLLDDSNFK 409
            ++L   +RLL+ +D+++R + V +L ++        T H  LV         L DSN K
Sbjct: 764 VEQLRELTRLLEAKDFRSRMEGVGQLLELCKAKTELVTAH--LVQVFDAFTPRLQDSNKK 821

Query: 410 VVHGTLEVLHLLVIRLGEQVQQFLGPVIAASVKVLADN 447
           V    LE    ++  L E     L P++ + +  +ADN
Sbjct: 822 VNQWALESFAKMIPLLRES----LHPMLLSIIITVADN 855


>gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens]
          Length = 1471

 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 57/227 (25%), Positives = 102/227 (44%), Gaps = 24/227 (10%)

Query: 362 QEDYKNRTQAVEEL------KQVLGKFNPSSTPHSSLVGFISLLYNLLDDSNFKVVHGTL 415
           Q+D   R Q  +EL      KQ         T    LV    L  + ++ SN+KVV   +
Sbjct: 14  QKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVD--GLATSWVNSSNYKVVLLGM 71

Query: 416 EVLHLLVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKE-VGPQQVLCL 474
           ++L  LV RL ++ +  +G V+ + +  L D K  ++++   + LK+M +   PQ V   
Sbjct: 72  DILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQAANPQYVWDR 131

Query: 475 LLEHLKHKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAF 534
           +L   KHK+ R RE +    I +L    ++   L K+   +   L D   +VR AA+ + 
Sbjct: 132 MLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSL 191

Query: 535 AVLASSMG-------------SGKTSILFKAVDTVELQDNGDGVMNA 568
             +   +G               + +++F   D  E+Q +G+ + +A
Sbjct: 192 VEIYRHVGERVRADLSKKGLPQSRLNVIFTKFD--EVQKSGNMIQSA 236


>gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens]
          Length = 1479

 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 57/227 (25%), Positives = 102/227 (44%), Gaps = 24/227 (10%)

Query: 362 QEDYKNRTQAVEEL------KQVLGKFNPSSTPHSSLVGFISLLYNLLDDSNFKVVHGTL 415
           Q+D   R Q  +EL      KQ         T    LV    L  + ++ SN+KVV   +
Sbjct: 14  QKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVD--GLATSWVNSSNYKVVLLGM 71

Query: 416 EVLHLLVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKE-VGPQQVLCL 474
           ++L  LV RL ++ +  +G V+ + +  L D K  ++++   + LK+M +   PQ V   
Sbjct: 72  DILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQAANPQYVWDR 131

Query: 475 LLEHLKHKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAF 534
           +L   KHK+ R RE +    I +L    ++   L K+   +   L D   +VR AA+ + 
Sbjct: 132 MLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSL 191

Query: 535 AVLASSMG-------------SGKTSILFKAVDTVELQDNGDGVMNA 568
             +   +G               + +++F   D  E+Q +G+ + +A
Sbjct: 192 VEIYRHVGERVRADLSKKGLPQSRLNVIFTKFD--EVQKSGNMIQSA 236


>gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens]
          Length = 1538

 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 57/227 (25%), Positives = 102/227 (44%), Gaps = 24/227 (10%)

Query: 362 QEDYKNRTQAVEEL------KQVLGKFNPSSTPHSSLVGFISLLYNLLDDSNFKVVHGTL 415
           Q+D   R Q  +EL      KQ         T    LV    L  + ++ SN+KVV   +
Sbjct: 14  QKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVD--GLATSWVNSSNYKVVLLGM 71

Query: 416 EVLHLLVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKE-VGPQQVLCL 474
           ++L  LV RL ++ +  +G V+ + +  L D K  ++++   + LK+M +   PQ V   
Sbjct: 72  DILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQAANPQYVWDR 131

Query: 475 LLEHLKHKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAF 534
           +L   KHK+ R RE +    I +L    ++   L K+   +   L D   +VR AA+ + 
Sbjct: 132 MLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSL 191

Query: 535 AVLASSMG-------------SGKTSILFKAVDTVELQDNGDGVMNA 568
             +   +G               + +++F   D  E+Q +G+ + +A
Sbjct: 192 VEIYRHVGERVRADLSKKGLPQSRLNVIFTKFD--EVQKSGNMIQSA 236


>gi|57863301 CLIP-associating protein 2 [Homo sapiens]
          Length = 1506

 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 55/196 (28%), Positives = 85/196 (43%), Gaps = 4/196 (2%)

Query: 360 LDQEDYKNRTQAVEELKQVLGKFNPSSTPHSSLVGF---ISLLYNLLDDSNFKVVHGTLE 416
           + Q+D   R Q  +EL   LG     S     L      +  L   +  SN++V    LE
Sbjct: 13  VQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDALTGWVGSSNYRVSLMGLE 72

Query: 417 VLHLLVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKEVGPQQVLC-LL 475
           +L   V RL  + + ++  VI A +  + D K  ++ E   + LKLM +V P   +   L
Sbjct: 73  ILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLILKLMDQVAPPMYIWEQL 132

Query: 476 LEHLKHKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAFA 535
               KHK+ R RE V    I +L  + ++   + KL   L     DS  +VR AA+ A  
Sbjct: 133 ASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILFGDSNSQVRDAAILAIV 192

Query: 536 VLASSMGSGKTSILFK 551
            +   +G      L+K
Sbjct: 193 EIYRHVGEKVRMDLYK 208


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 115/531 (21%), Positives = 189/531 (35%), Gaps = 94/531 (17%)

Query: 774  SSHQEKVYASLNFGSKTQQTFGS-QTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSP 832
            SS  +K+ A+      T++ F S  TE T+    N    ++     P  +   +PK T+ 
Sbjct: 5098 SSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHS----PALADSETPKATTQ 5153

Query: 833  LIISPKKSQDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRNHGENSQEKPPVQ 892
            ++I+                      +  P+P   +    SS+ T      N + +P   
Sbjct: 5154 MVITTT--------------------VGDPAPSTSMPVHGSSETT------NIKREPTYF 5187

Query: 893  LTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEKDSLPI 952
            LTP L  + +S+            P   S L  K    T+             E  S  +
Sbjct: 5188 LTPRLRETSTSQES--------SFPTDTSFLLSKVPTGTI------------TEVSSTGV 5227

Query: 953  DLS-ELNFKDKD---LDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSAMKLDLTMD 1008
            + S +++  D D   +  +     +  +  S+ K ++     T+    P+SA    L +D
Sbjct: 5228 NSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTLPLD 5287

Query: 1009 SPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCPTRLSSAKKK 1068
            + +  S    +S    G +    +T+ +   P     M+         P     SS    
Sbjct: 5288 TSTTLSQGGTHSTVTQG-FPYSEVTTLMGMGPGNVSWMTT--------PPVEETSSVSSL 5338

Query: 1069 ISHIAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLSSAPATCSQSVIS 1128
            +S  A  SPS  SS++PQ I S     T      SV+V    V G+ S    T S   +S
Sbjct: 5339 MSSPAMTSPSPVSSTSPQSIPSSPLPVTAL--PTSVLVTTTDVLGTTSPESVTSSPPNLS 5396

Query: 1129 SVENGDTFSIKQSIEPPS-------------GIYGRSVQQNISSYLDVENEKDAKV---- 1171
            S+ +    + K +    +             G  G   +   S   D E  K   +    
Sbjct: 5397 SITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTT 5456

Query: 1172 ------SISKSTYNKMRQKRKEEKELFHNKDCEKKEKNSWERMRHTGTEKMASESETPTG 1225
                  S+S ST N + Q  + + E   +     +E ++ E+   T TE   + S  PTG
Sbjct: 5457 STLGDTSVSTSTPN-ISQTNQIQTEPTASLSPRLRESSTSEKTSST-TETNTAFSYVPTG 5514

Query: 1226 AISQYKERMPSVTHSPEIMDLSELRPFSKPEIALTEALRLLADEDWEKKIE 1276
            AI+Q   R    +    I DL   RP   P+I+     RL       K  E
Sbjct: 5515 AITQ-ASRTEISSSRTSISDLD--RPTIAPDISTGMITRLFTSPIMTKSAE 5562



 Score = 37.0 bits (84), Expect = 0.17
 Identities = 66/272 (24%), Positives = 95/272 (34%), Gaps = 23/272 (8%)

Query: 826  SPKHTSPLIISPKKSQDN-SVNFSNSWPLKSFEGLSKPSPQKKLVSQKSS----DPTGRN 880
            S   +SP+ +S +K     S   S S     F G S       LV  ++S     PT   
Sbjct: 3025 SGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTL 3084

Query: 881  HGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPD 940
            +   SQE+PP   +   +           T    P     SLLP  +       +K  P 
Sbjct: 3085 N--MSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSP- 3141

Query: 941  DIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDS- 999
            + W     S+P   S +   D  L      SS  +  NS     A+ +GS+    SP S 
Sbjct: 3142 ETW-ASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSP 3200

Query: 1000 AMKLDL-TMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPC 1058
             M   L  M S   S SP I S   +  +     T  + TT +   + S           
Sbjct: 3201 EMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQS----------- 3249

Query: 1059 PTRLSSAKKKISHIAEQSPSAGSSSNPQQISS 1090
             T L S    ISH+   + S   S     +++
Sbjct: 3250 -TALGSGSTSISHLPTGTTSPTKSPTENMLAT 3280



 Score = 32.3 bits (72), Expect = 4.1
 Identities = 103/497 (20%), Positives = 187/497 (37%), Gaps = 72/497 (14%)

Query: 789  KTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSPLIISPKKSQDNSVNFS 848
            KT+ +F   +   +++   PSP +  LP     S  +SP   + L+ S      + ++ S
Sbjct: 7967 KTRPSFSLMSSPATTS---PSPVSSTLPE----SISSSPLPVTSLLTSGLAKTTDMLHKS 8019

Query: 849  NSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLN 908
            +     S   LS  S +    S+ ++D T + H  +++    V  + +   S S     +
Sbjct: 8020 SEPVTNSPANLSSTSVEILATSEVTTD-TEKTHPSSNRTVTDVGTSSSGHESTSFVLADS 8078

Query: 909  GTKPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEE 968
             T  V   P  I+   +   +ST      E   I      SL + L + +  +      E
Sbjct: 8079 QTSKVTS-PMVITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATE 8137

Query: 969  MHSSLRSLRNSA----------AKKRAKLSGSTSDLESPDSAMKLDLTMDSPSL---SSS 1015
            M + L  +   A          +  R  +SG      SP+++ +    + + S+   S+ 
Sbjct: 8138 MSTVLSGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAE 8197

Query: 1016 PNINSYSESGVYSQESL-TSSLSTTPQGKRIMSDIFPTFGSKPCPTRLS----------- 1063
              I + ++    + ES  T  +STTP      S +   F      T +S           
Sbjct: 8198 MMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQ 8257

Query: 1064 -------SAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLS 1116
                   SA   +S  A  SPS  SS+  +   S     T  L+   V+   +     +S
Sbjct: 8258 SSVEETSSASSLLSLPATTSPSPVSSTLVEDFPSASLPVTSLLNPGLVITTDR---MGIS 8314

Query: 1117 SAPATCSQSVISSVENGDTFSIKQSI-----EPPSGIYGRSVQQNISSY-------LDVE 1164
              P T S S +SS  +    +++ ++     +P +     +V+ +IS +        D E
Sbjct: 8315 REPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSE 8374

Query: 1165 NEK------------DAKVSISKSTYNKMRQKRKEEKELFHNKDCEKKEKNSWERMRHTG 1212
              K            +  VSIS S + +  + + E      +     +E +S ER+  + 
Sbjct: 8375 TPKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTS---SLTSGLRETSSSERI-SSA 8430

Query: 1213 TEKMASESETPTGAISQ 1229
            TE     SE P+GA ++
Sbjct: 8431 TEGSTVLSEVPSGATTE 8447


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 81/396 (20%), Positives = 134/396 (33%), Gaps = 27/396 (6%)

Query: 773  TSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSP 832
            TS H      +      +  T G   E  +S+    + G  +LP+   +S       TSP
Sbjct: 804  TSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSP 863

Query: 833  LIISPKKS------------QDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRN 880
            +     ++             + S  F +S P      LS  S     VS++S+    R 
Sbjct: 864  ISSGSMETTALPGSTTTPGLSERSTTFHSS-PRSPATTLSPASTTSSGVSEESTTSHSRP 922

Query: 881  HGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPD 940
               ++   P    TP L R  ++     G+          +LLP       VG     P 
Sbjct: 923  GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT-------TLLPASTTTXLVGEPTTSPI 975

Query: 941  DIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSA 1000
                 E  +LP   +     +K       +SS RS   + +      SG + +  +  S 
Sbjct: 976  SSGSTETTALPGSTTTAGLSEK---STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR 1032

Query: 1001 MKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKP--C 1058
                 T   P  ++ P ++  S +   S  S  ++LS        +     TF S P   
Sbjct: 1033 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGST 1092

Query: 1059 PTRLSSAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLSSA 1118
             T L       S + E S    SS+   + +     +T    E +          ++ + 
Sbjct: 1093 ETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1152

Query: 1119 PATCSQSV-ISSVENGDTFSIKQS-IEPPSGIYGRS 1152
            P T S  V +S+  +G   SI  +     S  +GRS
Sbjct: 1153 PTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRS 1188


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 68/254 (26%), Positives = 99/254 (38%), Gaps = 30/254 (11%)

Query: 808  PSPGAYILPSYPVSS----PRTSPKHTSPLII--SPKKSQDNSVNFSN-SWPLKSFEGLS 860
            PSP   +LP+ P+S+     +T P H S      S K S+ + V   +   P K  E  S
Sbjct: 154  PSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKS 213

Query: 861  KPSPQKKLVSQKSSDPTGRNHGENSQEK-------------PPVQLTPALVRSPSSRRGL 907
              S + +    KSS  T R  GE    K             P + L    + S S + G 
Sbjct: 214  S-SKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGG- 271

Query: 908  NGTKPVPPIPRGISLLPDKADLSTVGHK--KKEPDDIWKCEKDSLPIDLSELNFKDKDLD 965
                P PP PR  S  P  AD      K  KK      +    + P   S  +F DK   
Sbjct: 272  -PPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPA 330

Query: 966  QEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSA-MKLDLTMDSPSLSSSPNINS---- 1020
            +++  +    ++  +  + AK +    +  S D A  K +    SPS SSS + +S    
Sbjct: 331  KDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSD 390

Query: 1021 YSESGVYSQESLTS 1034
            +  S  +SQ  L S
Sbjct: 391  FEPSQNHSQGPLRS 404



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 48/207 (23%), Positives = 82/207 (39%), Gaps = 43/207 (20%)

Query: 928  DLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRN--------- 978
            D +    K  +P  + K E    P   SE     K+L++E+  SS  + R          
Sbjct: 183  DANKESSKTSKPHKVTK-EHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKE 241

Query: 979  ------SAAKKRAKLSGSTSDLES--------------PDSAMKLDLTMDSPSLSS---- 1014
                   AA K  K++   + LES              P ++ K   T DSP  S+    
Sbjct: 242  EKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQK 301

Query: 1015 -SPNINSYSESGVYSQESLTSSLS--------TTPQGKRIMSDIFPTFGSKPCPTRLSSA 1065
             S +  S S  G   + S +SS S        ++ +G+++ ++  P    K      S++
Sbjct: 302  KSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNS 361

Query: 1066 KKKISHIAEQSPSAGSSSNPQQISSFD 1092
            + + S  +E + S+ S+S+    SS D
Sbjct: 362  EDEASFKSESAQSSPSNSSSSSDSSSD 388


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 18/171 (10%)

Query: 921  SLLPDKADLSTVGHKKKEPDDIWKC----EKDSLPIDLSELNFKDKDLDQEEMHSSLRSL 976
            S+L +  D  + G ++ E +D+ K     ++D    DLS+ N    D  +EE  +  +S 
Sbjct: 143  SILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNL---DASEEEDSNKKKSN 199

Query: 977  RNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSL 1036
            R S +K R+  S S+S   SP S+     +    S SS     S S     S+ S + S 
Sbjct: 200  RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 259

Query: 1037 STTPQGKRIMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSPSAGSSSNPQQ 1087
            S + +G            S P     SS+        ++S S  SSS  ++
Sbjct: 260  SRSHRG-----------SSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRK 299


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 45/171 (26%), Positives = 72/171 (42%), Gaps = 18/171 (10%)

Query: 921  SLLPDKADLSTVGHKKKEPDDIWKC----EKDSLPIDLSELNFKDKDLDQEEMHSSLRSL 976
            S+L +  D  + G ++ E +D+ K     ++D    DLS+ N    D  +EE  +  +S 
Sbjct: 143  SILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNL---DASEEEDSNKKKSN 199

Query: 977  RNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSL 1036
            R S +K R+  S S+S   SP S+     +    S SS     S S     S+ S + S 
Sbjct: 200  RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 259

Query: 1037 STTPQGKRIMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSPSAGSSSNPQQ 1087
            S + +G            S P     SS+        ++S S  SSS  ++
Sbjct: 260  SRSHRG-----------SSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRK 299


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 68/316 (21%), Positives = 115/316 (36%), Gaps = 12/316 (3%)

Query: 925  DKADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKR 984
            D +D S          D  K E DS     S+ + K    D     SS  S  +S +   
Sbjct: 609  DSSDSSDSSDSSDSKSDSSKSESDS-----SDSDSKSDSSDSNSSDSSDNS-DSSDSSNS 662

Query: 985  AKLSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKR 1044
            +  S S+   +S DS+   D +  S S  SS + NS SES   S  S + S  ++     
Sbjct: 663  SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS-SESSDSSDSSDSDSSDSSDSSNS 721

Query: 1045 IMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKALSEDSV 1104
              SD   +  S    +  SS     S  ++ S S+ SS +    +S D + +   S+ S 
Sbjct: 722  NSSD---SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778

Query: 1105 VVVGKGVFGSLSSAPATCSQSVISSVENGDTFSIKQSIEPPSGIYGRSVQQNISSYLDVE 1164
                     S +S+ ++ S +   S  + D+     S +  S     S   N S   D  
Sbjct: 779  SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS--NSSDSSNSSDSSDSS 836

Query: 1165 NEKDAKVSISKSTYNKMRQKRKEEKELFHNKDCEKKEKNSWERMRHTGTEKMASESETPT 1224
            N  D+  S   S  +      + +     +        NS +    + + + ++ S++  
Sbjct: 837  NSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD 896

Query: 1225 GAISQYKERMPSVTHS 1240
             + S   +   S   S
Sbjct: 897  SSNSSDSDSSDSSNSS 912



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 92/463 (19%), Positives = 151/463 (32%), Gaps = 12/463 (2%)

Query: 762  SVGSDLQFLGTTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVS 821
            S GSD      + S      +  +  S +  +  S     SSN  + S  +    S    
Sbjct: 848  SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907

Query: 822  SPRTSPKHTSPLIISPKKSQDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRNH 881
            S  +S    S       +S ++S N ++S    S +            S  SSD +  + 
Sbjct: 908  SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSD 967

Query: 882  GENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPDD 941
              +S        + +   S SS    +            S   D +D S         D 
Sbjct: 968  SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS 1027

Query: 942  IWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSAM 1001
                   S   D S+ +      D  +   S  S  +S +   +  S S+   +S DS+ 
Sbjct: 1028 ----SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083

Query: 1002 KLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCPTR 1061
              D +  S S  SS + +S   S   S +S  SS S+        SD   +  S      
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSD--SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN- 1140

Query: 1062 LSSAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLSSAPAT 1121
             SS     S  ++ S S+ SS +     S D + +   S  S          S  S+ ++
Sbjct: 1141 -SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199

Query: 1122 CSQSVISSVENGDTFSIKQSIEPPSGIYGRSVQQNISSYLDVENEKDAKVSISKSTYNKM 1181
             S     S ++ D+     S +  S     S   N SS  D  +  D+  S + S  +  
Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSDSNESS--DSSDSSDSSDSSNSSDSSDS 1255

Query: 1182 RQKRKEEKELFHNKDCEKKEKNSWERMRHTGTEKMASESETPT 1224
                    +     D + K  N       + ++   S+S   T
Sbjct: 1256 SDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298



 Score = 40.0 bits (92), Expect = 0.020
 Identities = 60/246 (24%), Positives = 92/246 (37%), Gaps = 6/246 (2%)

Query: 933  GHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTS 992
            G+   +  D  K + DS   D S+ +      D  +  SS  S  +S +      S  +S
Sbjct: 533  GNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS-DSNSSSDSDSSDSDSSDSS 591

Query: 993  DLESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPT 1052
            D +S DS+   D    S S  SS + +S   S   S  S + S S+    K   SD   +
Sbjct: 592  DSDSSDSSNSSD---SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648

Query: 1053 FGSKPCPTRLSSAKKKISHIAEQSPSAGSSSNPQQISSFDF--TTTKALSEDSVVVVGKG 1110
              S    +  SS     S  ++ S S+ SSS+    +S D   ++  + S +S       
Sbjct: 649  DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708

Query: 1111 VFGSLSSAPATCSQSVISSVENGDTFSIKQSIEPPSGIYGRSVQQNISSYLDVENEKDAK 1170
               S  S+ ++ S S  S   N    S   +    S     S   + S   D  N  D+ 
Sbjct: 709  DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768

Query: 1171 VSISKS 1176
             S   S
Sbjct: 769  DSSDSS 774



 Score = 35.0 bits (79), Expect = 0.63
 Identities = 87/426 (20%), Positives = 138/426 (32%), Gaps = 28/426 (6%)

Query: 762  SVGSDLQFLGTTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVS 821
            S  SD      +S   +   +S +  S   ++  S++E  SS+  + S  +    S    
Sbjct: 593  SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652

Query: 822  SPRTSPKHTSPLIISPKKSQDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRNH 881
            +  +S    S        S D+S + S+S    S +            S  SSD +  + 
Sbjct: 653  NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS 712

Query: 882  GENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPDD 941
             ++S              S  S    N +              D +D S         D 
Sbjct: 713  SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS-----------SDSSDSSNSSDSSDSSDS 761

Query: 942  IWKCEK-DSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSA 1000
                +  DS     S  +    D +     S      NS+    +  S  +SD    DS+
Sbjct: 762  SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821

Query: 1001 MKLDLTMDSPSLSSSPNINSYSESGVYS----------QESLTSSLSTTPQGKRIMSDIF 1050
               D +  S S S S N +  S+S   S           +S  SS S+        SD  
Sbjct: 822  NSSDSSNSSDS-SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880

Query: 1051 PTFGSKPCPTRLSSAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKG 1110
             +  S        S+    S  ++ S S+ SS +    +S D + +   S++S       
Sbjct: 881  DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNS-----NS 935

Query: 1111 VFGSLSSAPATCSQSVISSVENGDTFSIKQSIEPPSGIYGRSVQQNISSYLDVENEKDAK 1170
               S SS  +  S S  SS  +  + S   S    S     S   N S   D  +  D+ 
Sbjct: 936  SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995

Query: 1171 VSISKS 1176
             S   S
Sbjct: 996  DSSDSS 1001



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 52/216 (24%), Positives = 77/216 (35%), Gaps = 4/216 (1%)

Query: 961  DKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINS 1020
            D D       S+     +S+    +  S  +SD    DS+ + D +  S S  SS + NS
Sbjct: 817  DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876

Query: 1021 YSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSPSAG 1080
               S   S +S  SS S+        SD   +  S    +  SS     S  +  S ++ 
Sbjct: 877  SDSSD--SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934

Query: 1081 SSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLSSAPATCSQSVISSVENGDTFSIKQ 1140
            SS +     S D + +   S+ S          S  S  +  S S  SS  +  + S   
Sbjct: 935  SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS 994

Query: 1141 SIEPPSGIYGRSVQQNISSYLDVENEKDAKVSISKS 1176
            S    S     S   + SS  D  N  D+  S   S
Sbjct: 995  SDSSDSSNSSDSSDSSDSS--DSSNSSDSSNSSDSS 1028


>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
            12A isoform b [Homo sapiens]
          Length = 943

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 111/576 (19%), Positives = 214/576 (37%), Gaps = 65/576 (11%)

Query: 759  KTGSVGSDLQFLGTTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSY 818
            KTGS G+  +   +    +EK  A +   + + +   S            +  AY+ P+ 
Sbjct: 355  KTGSYGALAEITASKEGQKEKDTAGVTRSASSPRLSSSLDNKEKEKDSKGTRLAYVAPTI 414

Query: 819  PVSSPRTSPKHTSPLIISPKKSQDNS-VNFSNSWPLKSFEG-LSKPSPQKKLVSQKSSDP 876
            P     TS        I  K+++D+S +  S+S+  + +E  L K S   +  +   S  
Sbjct: 415  PRRLASTSD-------IEEKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCS 467

Query: 877  TGRNHGEN-SQEKPPVQLTPALVRSPSSRRGL-NGTKPVPPIPRGISLLPDKADLSTVGH 934
             GR   +  S   P    TP +  +   ++ L + T     I  G S    ++  S    
Sbjct: 468  FGRRQDDLISSSVPSTTSTPTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSN--- 524

Query: 935  KKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDL 994
             +   +D  + EKDS+P  ++                   ++ N+AA      + +   +
Sbjct: 525  -RLWAEDSTEKEKDSVPTAVTI--------------PVAPTVVNAAASTTTLTTTTAGTV 569

Query: 995  ESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFG 1054
             S     +   +  +P         S S+    S+++  S  ST       + +   T G
Sbjct: 570  SSTTEVRERRRSYLTPVRDEE----SESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIG 625

Query: 1055 -SKPCPTRLSSAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKALSE--DSVVVVGKGV 1111
             S+   TR    ++K     E+          +  +S +    +  S   D      + V
Sbjct: 626  RSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPV 685

Query: 1112 FGSLSSAPATCSQSVISSVENGDTFSIKQSIEPPSGIYGRSVQQNISSYLDVENEKDAKV 1171
              S S+ P++   ++ SS+      +   S+   +  Y R + +   +  + E  ++ K 
Sbjct: 686  STSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKE--NEREGEKREEEKE 743

Query: 1172 SISKSTYNKMRQKRK-EEKELFHNKDCEKKEKNSWERMRHTGTEKMASESETPTGAISQY 1230
               KS    +R++R+  EK          ++ +  E+ + + TE+ +++ ET T +IS+Y
Sbjct: 744  GEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRY 803

Query: 1231 KERMPS--------VTHSPEIMDLSELRPFSKPEIALTEALRLLADE--DWEKKIEGLNF 1280
            +    S        +  S     L E +P+S          RL  D+  D++K  E +  
Sbjct: 804  ETSSTSAGDRYDSLLGRSGSYSYLEERKPYSS---------RLEKDDSTDFKKLYEQI-- 852

Query: 1281 IRCLAAFHSEILNTKLHETNFAVVQEVKNLRSGVSR 1316
                    +E L  +LH+TN  +      L     R
Sbjct: 853  -----LAENEKLKAQLHDTNMELTDLKLQLEKATQR 883


>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
            12A isoform a [Homo sapiens]
          Length = 1030

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 111/576 (19%), Positives = 214/576 (37%), Gaps = 65/576 (11%)

Query: 759  KTGSVGSDLQFLGTTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSY 818
            KTGS G+  +   +    +EK  A +   + + +   S            +  AY+ P+ 
Sbjct: 442  KTGSYGALAEITASKEGQKEKDTAGVTRSASSPRLSSSLDNKEKEKDSKGTRLAYVAPTI 501

Query: 819  PVSSPRTSPKHTSPLIISPKKSQDNS-VNFSNSWPLKSFEG-LSKPSPQKKLVSQKSSDP 876
            P     TS        I  K+++D+S +  S+S+  + +E  L K S   +  +   S  
Sbjct: 502  PRRLASTSD-------IEEKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCS 554

Query: 877  TGRNHGEN-SQEKPPVQLTPALVRSPSSRRGL-NGTKPVPPIPRGISLLPDKADLSTVGH 934
             GR   +  S   P    TP +  +   ++ L + T     I  G S    ++  S    
Sbjct: 555  FGRRQDDLISSSVPSTTSTPTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSN--- 611

Query: 935  KKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDL 994
             +   +D  + EKDS+P  ++                   ++ N+AA      + +   +
Sbjct: 612  -RLWAEDSTEKEKDSVPTAVTI--------------PVAPTVVNAAASTTTLTTTTAGTV 656

Query: 995  ESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFG 1054
             S     +   +  +P         S S+    S+++  S  ST       + +   T G
Sbjct: 657  SSTTEVRERRRSYLTPVRDEE----SESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIG 712

Query: 1055 -SKPCPTRLSSAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKALSE--DSVVVVGKGV 1111
             S+   TR    ++K     E+          +  +S +    +  S   D      + V
Sbjct: 713  RSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPV 772

Query: 1112 FGSLSSAPATCSQSVISSVENGDTFSIKQSIEPPSGIYGRSVQQNISSYLDVENEKDAKV 1171
              S S+ P++   ++ SS+      +   S+   +  Y R + +   +  + E  ++ K 
Sbjct: 773  STSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKE--NEREGEKREEEKE 830

Query: 1172 SISKSTYNKMRQKRK-EEKELFHNKDCEKKEKNSWERMRHTGTEKMASESETPTGAISQY 1230
               KS    +R++R+  EK          ++ +  E+ + + TE+ +++ ET T +IS+Y
Sbjct: 831  GEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRY 890

Query: 1231 KERMPS--------VTHSPEIMDLSELRPFSKPEIALTEALRLLADE--DWEKKIEGLNF 1280
            +    S        +  S     L E +P+S          RL  D+  D++K  E +  
Sbjct: 891  ETSSTSAGDRYDSLLGRSGSYSYLEERKPYSS---------RLEKDDSTDFKKLYEQI-- 939

Query: 1281 IRCLAAFHSEILNTKLHETNFAVVQEVKNLRSGVSR 1316
                    +E L  +LH+TN  +      L     R
Sbjct: 940  -----LAENEKLKAQLHDTNMELTDLKLQLEKATQR 970


>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit 12A
            isoform a [Homo sapiens]
          Length = 1030

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 111/576 (19%), Positives = 214/576 (37%), Gaps = 65/576 (11%)

Query: 759  KTGSVGSDLQFLGTTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSY 818
            KTGS G+  +   +    +EK  A +   + + +   S            +  AY+ P+ 
Sbjct: 442  KTGSYGALAEITASKEGQKEKDTAGVTRSASSPRLSSSLDNKEKEKDSKGTRLAYVAPTI 501

Query: 819  PVSSPRTSPKHTSPLIISPKKSQDNS-VNFSNSWPLKSFEG-LSKPSPQKKLVSQKSSDP 876
            P     TS        I  K+++D+S +  S+S+  + +E  L K S   +  +   S  
Sbjct: 502  PRRLASTSD-------IEEKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCS 554

Query: 877  TGRNHGEN-SQEKPPVQLTPALVRSPSSRRGL-NGTKPVPPIPRGISLLPDKADLSTVGH 934
             GR   +  S   P    TP +  +   ++ L + T     I  G S    ++  S    
Sbjct: 555  FGRRQDDLISSSVPSTTSTPTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSN--- 611

Query: 935  KKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDL 994
             +   +D  + EKDS+P  ++                   ++ N+AA      + +   +
Sbjct: 612  -RLWAEDSTEKEKDSVPTAVTI--------------PVAPTVVNAAASTTTLTTTTAGTV 656

Query: 995  ESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFG 1054
             S     +   +  +P         S S+    S+++  S  ST       + +   T G
Sbjct: 657  SSTTEVRERRRSYLTPVRDEE----SESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIG 712

Query: 1055 -SKPCPTRLSSAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKALSE--DSVVVVGKGV 1111
             S+   TR    ++K     E+          +  +S +    +  S   D      + V
Sbjct: 713  RSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPV 772

Query: 1112 FGSLSSAPATCSQSVISSVENGDTFSIKQSIEPPSGIYGRSVQQNISSYLDVENEKDAKV 1171
              S S+ P++   ++ SS+      +   S+   +  Y R + +   +  + E  ++ K 
Sbjct: 773  STSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKE--NEREGEKREEEKE 830

Query: 1172 SISKSTYNKMRQKRK-EEKELFHNKDCEKKEKNSWERMRHTGTEKMASESETPTGAISQY 1230
               KS    +R++R+  EK          ++ +  E+ + + TE+ +++ ET T +IS+Y
Sbjct: 831  GEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRY 890

Query: 1231 KERMPS--------VTHSPEIMDLSELRPFSKPEIALTEALRLLADE--DWEKKIEGLNF 1280
            +    S        +  S     L E +P+S          RL  D+  D++K  E +  
Sbjct: 891  ETSSTSAGDRYDSLLGRSGSYSYLEERKPYSS---------RLEKDDSTDFKKLYEQI-- 939

Query: 1281 IRCLAAFHSEILNTKLHETNFAVVQEVKNLRSGVSR 1316
                    +E L  +LH+TN  +      L     R
Sbjct: 940  -----LAENEKLKAQLHDTNMELTDLKLQLEKATQR 970


>gi|31543559 radial spoke 3 homolog [Homo sapiens]
          Length = 560

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 11/111 (9%)

Query: 1119 PATCSQSVISSVENGDTFSIKQSIEPPSGIY-GRSVQQNISSYLDVENEKDAKVSISKST 1177
            PA   + V + +  G+ F     ++P   +  G++++Q++   +  E E+ A +  S+  
Sbjct: 291  PAKTGKDVATQILEGELFDFDLEVKPVLEVLVGKTIEQSLLEVM--EEEELANLRASQRE 348

Query: 1178 YNKMRQ------KRKEEKELFHNKDCEKKEKNSWERM-RHTGT-EKMASES 1220
            Y ++R       +R EE+E  H ++ E+++K  WE M +H  T +K+A+ +
Sbjct: 349  YEELRNSERAEVQRLEEQERRHREEKERRKKQQWEIMHKHNETSQKIAARA 399


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 41.6 bits (96), Expect = 0.007
 Identities = 61/295 (20%), Positives = 109/295 (36%), Gaps = 38/295 (12%)

Query: 767  LQFLGTTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTS 826
            L F   T   + K+  +    +++  T  S +  +SS+  + S           SS  +S
Sbjct: 122  LTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSS---------SSSSSS 172

Query: 827  PKHTSPLIISPKKSQDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRNHGENSQ 886
               +S    S   S  +S +FS    L   E   KPS   +       +P+ R+H ++S+
Sbjct: 173  SSSSSSSSSSSSSSSSSSTSFSKPHKLMK-EHKEKPSKDSREHKSAFKEPS-RDHNKSSK 230

Query: 887  E--KPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLL------------------PDK 926
            E  K P +  P        +      KP+   P+  S L                   D 
Sbjct: 231  ESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDS 290

Query: 927  ADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAK 986
             +LS    KK   + ++K    + P+ L+    K +  D+  +      + +  ++K+  
Sbjct: 291  EELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKS 350

Query: 987  LSGSTSDLESPDSA-------MKLDLTMDSPSLSSSPNINSYSESGVYSQESLTS 1034
                  D+  P+ +        K D    SP+ SSS + +S++ S    Q  L S
Sbjct: 351  TLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRS 405


>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
          Length = 898

 Score = 41.6 bits (96), Expect = 0.007
 Identities = 104/470 (22%), Positives = 178/470 (37%), Gaps = 76/470 (16%)

Query: 1151 RSVQQNISSYLDVE----NEKDAKVSISKSTYNKMRQKRKEEKELFHNK-----DCEKKE 1201
            ++ Q  I +Y + E    NE DAK+ ++K    K  Q++ ++ E+ H K     D ++  
Sbjct: 432  KNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTF 491

Query: 1202 KNSWERMRHTGTEKMASESE--TPTGAISQYKE-------RMPSVTHSPEIMD-LSELRP 1251
            K   + +R   T+    E E       +S+YKE        + ++    +  D L E   
Sbjct: 492  KEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQ 551

Query: 1252 FSKPEIA-LTEALRLLAD--EDWEKKIEGLNFIRCLAAFHSEILNTKLHETNFAVVQEVK 1308
              K EI  L E +  L     D +K IEG           +E L +K    N  +  E  
Sbjct: 552  RGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSK----NAQLQSESN 607

Query: 1309 NLRSGVSRAAVVCLSDLFTYLKKSMDQELDTTVKVLLHKAGESNTFIREDVDKALRAMVN 1368
            +L+S   +  V C     + L+   +Q   T +  L  +  +     +E+V      +  
Sbjct: 608  SLQSQFDK--VSCSE---SQLQSQCEQMKQTNIN-LESRLLKEEELRKEEVQTLQAELAC 661

Query: 1369 NVTPARAVVSLINGGQRYYGRKMLFFMMCHPNFEKMLEKYVPS--KDLPYIKDSVRNLQQ 1426
              T  +A+ + +                     E++ ++ V    K    IKD  + LQQ
Sbjct: 662  RQTEVKALSTQV---------------------EELKDELVTQRRKHASSIKDLTKQLQQ 700

Query: 1427 KGLGEIPLDTPSAKGRRSHTGSVGNTRSSSVSRDAFNSAERAVTEVREVTRKSVPRNSLE 1486
                   LD   +        S+G+  SSS S +A +SAE       E T  SV  ++  
Sbjct: 701  ---ARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARSSAE---DRSPENTGSSVAVDNFP 754

Query: 1487 SAEYLKLITGLLNAKDFRDRIN--------GIKQLLSDTENNQDLVVGNIVKIFDAFKSR 1538
              +   LI  ++  +    R N         IKQL+ +      ++   I++      S 
Sbjct: 755  QVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYILREESGTLSS 814

Query: 1539 LHDSNSKVNL-------VALETMHKMIPLLRDHLSPIINMLIPAIVDNNL 1581
                 +KV+L        +L T H     L   LS  IN  + A++++ L
Sbjct: 815  EASDFNKVHLSRRGGIMASLYTSHPADNGLTLELSLEINRKLQAVLEDTL 864


>gi|209863002 MAP-kinase activating death domain-containing protein
            isoform j [Homo sapiens]
          Length = 1541

 Score = 41.2 bits (95), Expect = 0.009
 Identities = 62/231 (26%), Positives = 97/231 (41%), Gaps = 30/231 (12%)

Query: 867  KLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDK 926
            +L +QK ++  G +  ENSQE PP++ + +   S S    ++G       P   + + DK
Sbjct: 675  ELQNQKEAEEPGPD-SENSQENPPLRSSSSTTASSSPSTVIHGANSE---PADSTEMDDK 730

Query: 927  ADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAK 986
            A    VG  K  P         S+P  + + N    D  Q E+    + L    + + A 
Sbjct: 731  A---AVGVSKPLP---------SVPPSIGKSNV---DRRQAEIGEGAQKLLRPNSLRLA- 774

Query: 987  LSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLS--TTP-QGK 1043
               S SD ES   A   + T+ + S      I S++ S +Y   S + SLS  T P +G 
Sbjct: 775  ---SDSDAESDSRASSPNSTVSNTSTEGFGGIMSFA-SSLYRNHSTSFSLSNLTLPTKGA 830

Query: 1044 RIMSDIFPTF--GSKPCPTRLSSAKKKISHIAEQSPS-AGSSSNPQQISSF 1091
            R  +  FP+     +    + SS  K    +  + PS  G SSN  +   F
Sbjct: 831  REKATPFPSLKGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQF 881


>gi|209862998 MAP-kinase activating death domain-containing protein
            isoform i [Homo sapiens]
          Length = 1544

 Score = 41.2 bits (95), Expect = 0.009
 Identities = 62/231 (26%), Positives = 97/231 (41%), Gaps = 30/231 (12%)

Query: 867  KLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDK 926
            +L +QK ++  G +  ENSQE PP++ + +   S S    ++G       P   + + DK
Sbjct: 675  ELQNQKEAEEPGPD-SENSQENPPLRSSSSTTASSSPSTVIHGANSE---PADSTEMDDK 730

Query: 927  ADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAK 986
            A    VG  K  P         S+P  + + N    D  Q E+    + L    + + A 
Sbjct: 731  A---AVGVSKPLP---------SVPPSIGKSNV---DRRQAEIGEGAQKLLRPNSLRLA- 774

Query: 987  LSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLS--TTP-QGK 1043
               S SD ES   A   + T+ + S      I S++ S +Y   S + SLS  T P +G 
Sbjct: 775  ---SDSDAESDSRASSPNSTVSNTSTEGFGGIMSFA-SSLYRNHSTSFSLSNLTLPTKGA 830

Query: 1044 RIMSDIFPTF--GSKPCPTRLSSAKKKISHIAEQSPS-AGSSSNPQQISSF 1091
            R  +  FP+     +    + SS  K    +  + PS  G SSN  +   F
Sbjct: 831  REKATPFPSLKGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQF 881


>gi|209862987 MAP-kinase activating death domain-containing protein
            isoform f [Homo sapiens]
          Length = 1479

 Score = 41.2 bits (95), Expect = 0.009
 Identities = 62/231 (26%), Positives = 97/231 (41%), Gaps = 30/231 (12%)

Query: 867  KLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDK 926
            +L +QK ++  G +  ENSQE PP++ + +   S S    ++G       P   + + DK
Sbjct: 675  ELQNQKEAEEPGPD-SENSQENPPLRSSSSTTASSSPSTVIHGANSE---PADSTEMDDK 730

Query: 927  ADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAK 986
            A    VG  K  P         S+P  + + N    D  Q E+    + L    + + A 
Sbjct: 731  A---AVGVSKPLP---------SVPPSIGKSNV---DRRQAEIGEGAQKLLRPNSLRLA- 774

Query: 987  LSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLS--TTP-QGK 1043
               S SD ES   A   + T+ + S      I S++ S +Y   S + SLS  T P +G 
Sbjct: 775  ---SDSDAESDSRASSPNSTVSNTSTEGFGGIMSFA-SSLYRNHSTSFSLSNLTLPTKGA 830

Query: 1044 RIMSDIFPTF--GSKPCPTRLSSAKKKISHIAEQSPS-AGSSSNPQQISSF 1091
            R  +  FP+     +    + SS  K    +  + PS  G SSN  +   F
Sbjct: 831  REKATPFPSLKGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQF 881


>gi|209862979 MAP-kinase activating death domain-containing protein
            isoform c [Homo sapiens]
          Length = 1545

 Score = 41.2 bits (95), Expect = 0.009
 Identities = 62/231 (26%), Positives = 97/231 (41%), Gaps = 30/231 (12%)

Query: 867  KLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDK 926
            +L +QK ++  G +  ENSQE PP++ + +   S S    ++G       P   + + DK
Sbjct: 675  ELQNQKEAEEPGPD-SENSQENPPLRSSSSTTASSSPSTVIHGANSE---PADSTEMDDK 730

Query: 927  ADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAK 986
            A    VG  K  P         S+P  + + N    D  Q E+    + L    + + A 
Sbjct: 731  A---AVGVSKPLP---------SVPPSIGKSNV---DRRQAEIGEGAQKLLRPNSLRLA- 774

Query: 987  LSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLS--TTP-QGK 1043
               S SD ES   A   + T+ + S      I S++ S +Y   S + SLS  T P +G 
Sbjct: 775  ---SDSDAESDSRASSPNSTVSNTSTEGFGGIMSFA-SSLYRNHSTSFSLSNLTLPTKGA 830

Query: 1044 RIMSDIFPTF--GSKPCPTRLSSAKKKISHIAEQSPS-AGSSSNPQQISSF 1091
            R  +  FP+     +    + SS  K    +  + PS  G SSN  +   F
Sbjct: 831  REKATPFPSLKGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQF 881


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 41.2 bits (95), Expect = 0.009
 Identities = 96/490 (19%), Positives = 157/490 (32%), Gaps = 45/490 (9%)

Query: 773  TSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSP 832
            TS H      +      +  T G   E T+S+    + G  +LP+   +S       TSP
Sbjct: 42   TSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP 101

Query: 833  LIISPKKS------------QDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRN 880
            +     ++             + S  F +S P      LS  S     VS++S+    R 
Sbjct: 102  ISSGSMETTALPGSTTTPGLSEKSTTFHSS-PRSPATTLSPASTTSSGVSEESTTSHSRP 160

Query: 881  HGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPD 940
               ++   P    TP L R  ++     G+     +P   +      + ST  H      
Sbjct: 161  GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE-STTSHSSPGST 219

Query: 941  DIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSA 1000
            D       +  +   +        +    HSS  S   +        SG         S+
Sbjct: 220  DTALSPGSTTALSFGQ--------ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSS 271

Query: 1001 MKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKP--C 1058
                 T  SP+ S+SP +   S +   +  + T +  + P       +   T+   P   
Sbjct: 272  TGSPRTTLSPASSTSPGLQGES-TAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 330

Query: 1059 PTRLSSAKKKISHIAEQSPSAGSSSNPQQIS-SFDFTTTKALSEDSVVVVGK------GV 1111
            PT    A    S  +E+S    SS +    + S   +TT  +SE+S     +        
Sbjct: 331  PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTA 390

Query: 1112 FGSLSSAPATCSQSVISSVENGDTFSIKQSIEPPSGIYGRSVQQNISSYLDVENEKDAKV 1171
            F   ++      +   S    G T +   +   P G     V+ + + +    +      
Sbjct: 391  FPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHF 450

Query: 1172 SISKSTYNKMRQKRKEEKELFHNKDCEKKEKNSWERMRHTGTEKMASESETPTGAISQYK 1231
            S S +T       R EE    H+         S E     G+   A  SE  T   S   
Sbjct: 451  SASSTTLG-----RSEESTTVHS------SPGSTETTALPGSTTTAGLSEKSTTFYS--S 497

Query: 1232 ERMPSVTHSP 1241
             R P  T SP
Sbjct: 498  PRSPDTTLSP 507



 Score = 35.0 bits (79), Expect = 0.63
 Identities = 83/365 (22%), Positives = 131/365 (35%), Gaps = 65/365 (17%)

Query: 772  TTSSHQE--KVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKH 829
            +T+SH        +L+ GS T  +FG ++    S     SPG+     +P S+       
Sbjct: 209  STTSHSSPGSTDTALSPGSTTALSFGQESTTFHS-----SPGSTHTTLFPDST------- 256

Query: 830  TSPLIISPKKSQDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRNHGENSQEKP 889
            TS  I+         V+ S   P  +    S  SP  +  S          H   S   P
Sbjct: 257  TSSGIVEAS----TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS---P 309

Query: 890  PVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEKDS 949
            P   T  +  S +  R   G+ P    P         A  +T GH +K    I+    D+
Sbjct: 310  PSTATAPVEESTTYHRS-PGSTPTTHFP---------ASSTTSGHSEKST--IFHSSPDA 357

Query: 950  LPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDS 1009
                                HS+   +   ++   ++  GST     PDS     L+ + 
Sbjct: 358  ------------SGTTPSSAHSTTSGVSEESSTSHSQ-PGSTHTTAFPDSTTTSGLSQE- 403

Query: 1010 PSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMS---DIFPTFGSKPC--PTRLSS 1064
            P+ S S            SQ S  ++L TTP      +   ++  T+ S+P   PT   S
Sbjct: 404  PTTSHS------------SQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFS 451

Query: 1065 AKKKISHIAEQSPSAGSSSNPQQISSFD-FTTTKALSEDSVVVVGKGVFGSLSSAPATCS 1123
            A       +E+S +  SS    + ++    TTT  LSE S            + +PA+ +
Sbjct: 452  ASSTTLGRSEESTTVHSSPGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTT 511

Query: 1124 QSVIS 1128
             S +S
Sbjct: 512  SSGVS 516


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 40.4 bits (93), Expect = 0.015
 Identities = 88/366 (24%), Positives = 135/366 (36%), Gaps = 25/366 (6%)

Query: 773  TSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSP 832
            TS H      +      +  T G   E T+S+    + G  +LP+   +S       TSP
Sbjct: 4606 TSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP 4665

Query: 833  LIISPKKSQDNSVNFSNSWP---LKSFEGLSKPSPQKKLVSQKSSDPTGRNHGENSQEKP 889
              IS    +  ++  S + P    KS    S PS         SS   GR+    +    
Sbjct: 4666 --ISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSS 4723

Query: 890  PV--QLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEK 947
            PV    TP+  RS +S  GL           G +      + ST   + +E     +   
Sbjct: 4724 PVATATTPSPARSTTS--GLVEESTAYHSSPGSTQTMHFPESSTASGRSEES----RTSH 4777

Query: 948  DSLPIDLSELNFKDKDLDQE--EMHSSLRSLRNSAAKKRAKLSG----STSDLESPDSAM 1001
             S    +S        L +E    HSS  S+  +   + +  SG    ST+   SPD+  
Sbjct: 4778 SSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNG 4837

Query: 1002 KLDLTMD-SPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCPT 1060
               L    + S   + +   Y   G  S E+  +S +TTP G    S I  +    P  T
Sbjct: 4838 ITPLPAHFTTSGRIAESTTFYISPG--SMETTLASTATTP-GLSAKSTILYSSSRSPDQT 4894

Query: 1061 RLSSAKKKISHIAEQSPSAGSSSNPQQISSFD-FTTTKALSEDSVVVVGKGVFGSLSSAP 1119
             LS A    S I+ +  S  S +     ++F   TTT  LS++S     K      + +P
Sbjct: 4895 -LSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSP 4953

Query: 1120 ATCSQS 1125
             + + S
Sbjct: 4954 GSITTS 4959



 Score = 40.0 bits (92), Expect = 0.020
 Identities = 101/503 (20%), Positives = 171/503 (33%), Gaps = 65/503 (12%)

Query: 773  TSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSP 832
            TS H      +      +  T G   E T+S+    + G  +LP+   +S       TSP
Sbjct: 3523 TSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP 3582

Query: 833  LIISPKKS------------QDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRN 880
            +     ++             + S  F +S P      LS  S     VS++S+    R 
Sbjct: 3583 ISSGSMETTALPGSTTTPGLSEKSTTFHSS-PRSPATTLSPASTTSSGVSEESTTSHSRP 3641

Query: 881  HGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPD 940
               ++   P    TP L R  ++     G+     +P   +      + ST  H      
Sbjct: 3642 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQE-STTSHSSSGST 3700

Query: 941  DIWKCEKDSLPIDLSELN--------------FKDKDLDQEEMHSSLRSLRNSAAKKRAK 986
            D       +  +   + +              F D       + +S R + +S    R  
Sbjct: 3701 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTR-VHSSTGSPRTT 3759

Query: 987  LSGSTS---DLESPDSAMK-----LDLTMDSPSLSSSPNINSYSESGVY-----SQESLT 1033
            LS ++S    L+   +A +        T   PS +++P      ES  Y     S  +  
Sbjct: 3760 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP----VEESTTYHRSPGSTPTTH 3815

Query: 1034 SSLSTTPQGKRIMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSPSAGSSSNPQQISSFDF 1093
               S+T  G    S IF +       T  SSA    S   E + S  S  + +  +    
Sbjct: 3816 FPASSTTSGHSEKSTIFHS-SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGS 3874

Query: 1094 TTTKALSEDSVVVVGKGVFGSLSSAPATCS------QSVISSVENGDTFSIKQSIEPPSG 1147
            TTT  LSE S          + + +PA+ +      +S  S  + G T S   ++ P S 
Sbjct: 3875 TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS---TVSPAST 3931

Query: 1148 IYGRSVQQNISSYLDVENEKDAKVSISKSTYNKMRQKRKEEKELFHNKDCEK-----KEK 1202
                  +++ + Y       +  V   +ST   +   R+EE   FH++          E 
Sbjct: 3932 TTPGLSEESTTVYSSSPGSTETTV-FPRSTTTSV---RREEPTTFHSRPASTHTTLFTED 3987

Query: 1203 NSWERMRHTGTEKMASESETPTG 1225
            ++   +    T    S + T TG
Sbjct: 3988 STTSGLTEESTAFPGSPASTQTG 4010



 Score = 38.1 bits (87), Expect = 0.074
 Identities = 92/432 (21%), Positives = 150/432 (34%), Gaps = 61/432 (14%)

Query: 736  TTGTHQTNLS-GKCAQLGFSQ----ICGKTGSVGSDLQFLGTTSSHQEKVYASLNFGSKT 790
            ++G+  T LS G    L F Q         GS  + L    TTSS   +    ++  + +
Sbjct: 1056 SSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 1115

Query: 791  QQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSPLIISPKKSQDNSVNFSNS 850
             +T  S    TS   Q  S      P+   ++P  SP  T+   +    +   S     S
Sbjct: 1116 PRTTLSPASSTSPGLQGESTAFQTHPASTHTTP--SPPSTATAPVEESTTYHRS---PGS 1170

Query: 851  WPLKSFEGLSKPS--PQKKLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLN 908
             P   F   S  S   +K  +   S D +G               TP+   S +S RG +
Sbjct: 1171 TPTTHFPASSTTSGHSEKSTIFHSSPDASGT--------------TPSSAHSTTSGRGES 1216

Query: 909  GTKPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEKDSL-PIDLSELNFKDKDLDQE 967
             T  + P    I+ LP       +           +    +L P  ++ L   ++     
Sbjct: 1217 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 1276

Query: 968  EMHSSLRSLRNSAAKKRAKLSGSTSDLES------------------------------P 997
                S  S  + A+     LS  ++ + S                              P
Sbjct: 1277 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRP 1336

Query: 998  DSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKP 1057
             S      T DS +   +    ++  S   +Q  L ++L+T   G+   S  FP+  S  
Sbjct: 1337 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE--STTFPS-SSGS 1393

Query: 1058 CPTRLSSAKKKISH-IAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLS 1116
              T+LS A+   S  + E +PS  S S+ +  +     TT +LSE S            +
Sbjct: 1394 TGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 1453

Query: 1117 SAPATCSQSVIS 1128
             +PAT + S +S
Sbjct: 1454 LSPATTTSSGVS 1465



 Score = 38.1 bits (87), Expect = 0.074
 Identities = 92/432 (21%), Positives = 150/432 (34%), Gaps = 61/432 (14%)

Query: 736  TTGTHQTNLS-GKCAQLGFSQ----ICGKTGSVGSDLQFLGTTSSHQEKVYASLNFGSKT 790
            ++G+  T LS G    L F Q         GS  + L    TTSS   +    ++  + +
Sbjct: 3696 SSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 3755

Query: 791  QQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSPLIISPKKSQDNSVNFSNS 850
             +T  S    TS   Q  S      P+   ++P  SP  T+   +    +   S     S
Sbjct: 3756 PRTTLSPASSTSPGLQGESTAFQTHPASTHTTP--SPPSTATAPVEESTTYHRS---PGS 3810

Query: 851  WPLKSFEGLSKPS--PQKKLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLN 908
             P   F   S  S   +K  +   S D +G               TP+   S +S RG +
Sbjct: 3811 TPTTHFPASSTTSGHSEKSTIFHSSPDASGT--------------TPSSAHSTTSGRGES 3856

Query: 909  GTKPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEKDSL-PIDLSELNFKDKDLDQE 967
             T  + P    I+ LP       +           +    +L P  ++ L   ++     
Sbjct: 3857 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 3916

Query: 968  EMHSSLRSLRNSAAKKRAKLSGSTSDLES------------------------------P 997
                S  S  + A+     LS  ++ + S                              P
Sbjct: 3917 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRP 3976

Query: 998  DSAMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKP 1057
             S      T DS +   +    ++  S   +Q  L ++L+T   G+   S  FP+  S  
Sbjct: 3977 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE--STTFPS-SSGS 4033

Query: 1058 CPTRLSSAKKKISH-IAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLS 1116
              T+LS A+   S  + E +PS  S S+ +  +     TT +LSE S            +
Sbjct: 4034 TGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 4093

Query: 1117 SAPATCSQSVIS 1128
             +PAT + S +S
Sbjct: 4094 LSPATTTSSGVS 4105



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 84/408 (20%), Positives = 139/408 (34%), Gaps = 52/408 (12%)

Query: 773  TSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSP 832
            TS H      +      +  T G   E T+S+    + G  +LP+   +S       TSP
Sbjct: 883  TSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP 942

Query: 833  LIISPKKS------------QDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRN 880
            +     ++             + S  F +S P      LS  S     VS++S+    R 
Sbjct: 943  ISSGSMETTALPGSTTTPGLSERSTTFHSS-PRSPATTLSPASTTSSGVSEESTTSRSRP 1001

Query: 881  HGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPD 940
               ++   P    TP L R  ++     G+     +P   +      + ST  H      
Sbjct: 1002 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE-STTSHSSSGST 1060

Query: 941  DIWKCEKDSLPIDLSELN--------------FKDKDLDQEEMHSSLRSLRNSAAKKRAK 986
            D       +  +   + +              F D       + +S R + +S    R  
Sbjct: 1061 DTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTR-VHSSTGSPRTT 1119

Query: 987  LSGSTS---DLESPDSAMK-----LDLTMDSPSLSSSPNINSYSESGVY-----SQESLT 1033
            LS ++S    L+   +A +        T   PS +++P      ES  Y     S  +  
Sbjct: 1120 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP----VEESTTYHRSPGSTPTTH 1175

Query: 1034 SSLSTTPQGKRIMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSPSAGSSSNPQQISSFDF 1093
               S+T  G    S IF +       T  SSA    S   E + S  S  + +  +    
Sbjct: 1176 FPASSTTSGHSEKSTIFHS-SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGS 1234

Query: 1094 TTTKALSEDSVVVVGKGVFGSLSSAPATCSQSVISSVENGDTFSIKQS 1141
            TTT  LSE S        + S  S   T S + ++S+  G+  +  +S
Sbjct: 1235 TTTPGLSEASTT-----FYSSPRSPTTTLSPASMTSLGVGEESTTSRS 1277



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 75/391 (19%), Positives = 128/391 (32%), Gaps = 28/391 (7%)

Query: 773  TSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSP 832
            TS H      +      +  T G   E T+S+    + G  +LP+   +S       TSP
Sbjct: 1966 TSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP 2025

Query: 833  LIISPKKS------------QDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGRN 880
            +     ++             + S  F +S P      LS  S     VS++S+    R 
Sbjct: 2026 ISSGSMETTALPGSTTTPGLSEKSTTFHSS-PRSPATTLSPASTTSSGVSEESTTSHSRP 2084

Query: 881  HGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEPD 940
               ++   P    TP L R  ++     G+     +P   +      + ST  H      
Sbjct: 2085 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE-STTSHSSPGST 2143

Query: 941  DIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSA 1000
            D       +  +   +        +    HSS  S   +        SG         S+
Sbjct: 2144 DTALSPGSTTALSFGQ--------ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSS 2195

Query: 1001 MKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKP--C 1058
                 T  SP+ S+SP +   S +   +  + T +  + P       +   T+   P   
Sbjct: 2196 TGSPRTTLSPASSTSPGLQGES-TAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 2254

Query: 1059 PTRLSSAKKKISHIAEQSP---SAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSL 1115
            PT    A    S  +E+S    S+  +S     S+   T+ +  S  S +  G     +L
Sbjct: 2255 PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTL 2314

Query: 1116 SSAPATCSQSVISSVENGDTFSIKQSIEPPS 1146
              +  T   S  S+       S   ++ P S
Sbjct: 2315 PGSTTTPGLSEASTTFYSSPRSPTTTLSPAS 2345



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 92/430 (21%), Positives = 147/430 (34%), Gaps = 61/430 (14%)

Query: 738  GTHQTNLS-GKCAQLGFSQ----ICGKTGSVGSDLQFLGTTSSHQEKVYASLNFGSKTQQ 792
            G+  T LS G    L F Q         GS  + L    TTSS   +    ++  + + +
Sbjct: 2141 GSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPR 2200

Query: 793  TFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSPLIISPKKSQDNSVNFSNSWP 852
            T  S    TS   Q  S      P+   ++P  SP  T+   +    +   S     S P
Sbjct: 2201 TTLSPASSTSPGLQGESTAFQTHPASTHTTP--SPPSTATAPVEESTTYHRS---PGSTP 2255

Query: 853  LKSFEGLSKPS--PQKKLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGT 910
               F   S  S   +K  +   S D +G               TP+   S +S RG + T
Sbjct: 2256 TTHFPASSTTSGHSEKSTIFHSSPDASGT--------------TPSSAHSTTSGRGESTT 2301

Query: 911  KPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEKDSL-PIDLSELNFKDKDLDQEEM 969
              + P    I+ LP       +           +    +L P  ++ L   ++       
Sbjct: 2302 SRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQ 2361

Query: 970  HSSLRSLRNSAAKKRAKLSGSTSDLES------------------------------PDS 999
              S  S  + A+     LS  ++ + S                              P S
Sbjct: 2362 PGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPAS 2421

Query: 1000 AMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCP 1059
                  T DS +   +    ++  S   +Q  L ++L+T   G+   S  FP+  S    
Sbjct: 2422 THTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE--STTFPS-SSGSTG 2478

Query: 1060 TRLSSAKKKISH-IAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLSSA 1118
            T LS A+   S  + E +PS  S S+ +  +     TT +LSE S            + +
Sbjct: 2479 TTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 2538

Query: 1119 PATCSQSVIS 1128
            PAT + S +S
Sbjct: 2539 PATTTSSGVS 2548



 Score = 35.4 bits (80), Expect = 0.48
 Identities = 92/430 (21%), Positives = 147/430 (34%), Gaps = 61/430 (14%)

Query: 738  GTHQTNLS-GKCAQLGFSQ----ICGKTGSVGSDLQFLGTTSSHQEKVYASLNFGSKTQQ 792
            G+  T LS G    L F Q         GS  + L    TTSS   +    ++  + + +
Sbjct: 2615 GSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPR 2674

Query: 793  TFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTSPLIISPKKSQDNSVNFSNSWP 852
            T  S    TS   Q  S      P+   ++P  SP  T+   +    +   S     S P
Sbjct: 2675 TTLSPASSTSPGLQGESTTFQTHPASTHTTP--SPPSTATAPVEESTTYHRS---PGSTP 2729

Query: 853  LKSFEGLSKPS--PQKKLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGT 910
               F   S  S   +K  +   S D +G               TP+   S +S RG + T
Sbjct: 2730 TTHFPASSTTSGHSEKSTIFHSSPDASGT--------------TPSSAHSTTSGRGESTT 2775

Query: 911  KPVPPIPRGISLLPDKADLSTVGHKKKEPDDIWKCEKDSL-PIDLSELNFKDKDLDQEEM 969
              + P    I+ LP       +           +    +L P  ++ L   ++       
Sbjct: 2776 SRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQ 2835

Query: 970  HSSLRSLRNSAAKKRAKLSGSTSDLES------------------------------PDS 999
              S  S  + A+     LS  ++ + S                              P S
Sbjct: 2836 PGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPAS 2895

Query: 1000 AMKLDLTMDSPSLSSSPNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCP 1059
                  T DS +   +    ++  S   +Q  L ++L+T   G+   S  FP+  S    
Sbjct: 2896 THTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE--STTFPS-SSGSTG 2952

Query: 1060 TRLSSAKKKISH-IAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGSLSSA 1118
            T LS A+   S  + E +PS  S S+ +  +     TT +LSE S            + +
Sbjct: 2953 TTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 3012

Query: 1119 PATCSQSVIS 1128
            PAT + S +S
Sbjct: 3013 PATTTSSGVS 3022



 Score = 35.4 bits (80), Expect = 0.48
 Identities = 83/389 (21%), Positives = 140/389 (35%), Gaps = 29/389 (7%)

Query: 753  FSQICGKTGSVGSDLQFLGTTSSHQEKVYASLNFG-----SKTQQTFGSQTECTSSNGQN 807
            F++    +G       F G+ +S Q  + A+L        S T  +    T  T S  ++
Sbjct: 2901 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARS 2960

Query: 808  PSPGAYILPSYPVSSPRTSPKHTSPLIISPKKSQDNSVNFSNSWPLKSFEGLSKPSPQKK 867
             + G     +    SP ++   T P   +     + S  F  S P      LS  +    
Sbjct: 2961 TTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTS-PRSPDATLSPATTTSS 3019

Query: 868  LVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKA 927
             VS++SS    +    ++   P    T  L + P++     G+      P G +      
Sbjct: 3020 GVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSP-GSTTASSLG 3078

Query: 928  DLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKL 987
              ST  H    P D    E   LP D       +          SL +    A+   A L
Sbjct: 3079 QQSTTFHSS--PGDT---ETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGL 3133

Query: 988  SGSTSDLESPDSAMKLDLTMDSPSLSSSP-NINSYSESGVYSQESLTSSLSTTPQGKRIM 1046
               ++  +S  S+   D T   P  +++P  +++   S   S  +   S S+T  G+   
Sbjct: 3134 QEESTTFQSWPSSS--DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGR--- 3188

Query: 1047 SDIFPTFGSKP-------CPTRLSSAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKAL 1099
            S+   T  S P        PTR +++      + E + S  SS + +  +    TTT  L
Sbjct: 3189 SEESTTVHSSPGATGTALFPTRSATSVL----VGEPTTSPISSGSTETTALPGSTTTAGL 3244

Query: 1100 SEDSVVVVGKGVFGSLSSAPATCSQSVIS 1128
            SE S            + +PA+ + S +S
Sbjct: 3245 SEKSTTFYSSPRSPDTTLSPASTTSSGVS 3273



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 85/397 (21%), Positives = 148/397 (37%), Gaps = 45/397 (11%)

Query: 753  FSQICGKTGSVGSDLQFLGTTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGA 812
            F++    +G       F G+ +S Q  + A+L      +++    T   SS+G   S G 
Sbjct: 1344 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEES----TTFPSSSG---STGT 1396

Query: 813  YILPSYPVSSPRTSPKHTSPLIISPKKSQDNSVNFSNSWPLKSFEGL----SKPSPQKKL 868
             + P+   +S       ++P  +SP  ++  ++  S + P  S +      S  SP   L
Sbjct: 1397 KLSPARSTTSGLVG--ESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 1454

Query: 869  ---------VSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRG 919
                     VS++SS    +    ++   P    T  L + P++     G+      P G
Sbjct: 1455 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSP-G 1513

Query: 920  ISLLPDKADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNS 979
             +        ST  H    P D    E   LP D       +          SL +    
Sbjct: 1514 STTASSLGQQSTTFHSS--PGDT---ETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTP 1568

Query: 980  AAKKRAKLSGSTSDLESPDSAMKLDLTMDSPSLSSSP-NINSYSESGVYSQESLTSSLST 1038
            A+   A L   ++  +S  S+   D T   P  +++P  +++   S   S  +   S S+
Sbjct: 1569 ASSTSAGLQEESTTFQSWPSSS--DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASS 1626

Query: 1039 TPQGKRIMSDIFPTFGSKP-------CPTRLSSAKKKISHIAEQSPSAGSSSNPQQISSF 1091
            T  G+   S+   T  S P        PTR +++      + E + S  SS + +  +  
Sbjct: 1627 TTLGR---SEESTTVHSSPGATGTALFPTRSATSVL----VGEPTTSPISSGSTETTALP 1679

Query: 1092 DFTTTKALSEDSVVVVGKGVFGSLSSAPATCSQSVIS 1128
              TTT  LSE S            + +PA+ + S +S
Sbjct: 1680 GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVS 1716



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 86/401 (21%), Positives = 150/401 (37%), Gaps = 53/401 (13%)

Query: 753  FSQICGKTGSVGSDLQFLGTTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGA 812
            F++    +G       F G+ +S Q  + A+L      +++    T   SS+G   S G 
Sbjct: 3984 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEES----TTFPSSSG---STGT 4036

Query: 813  YILPSYPVSSPRTSPKHTSPLIISPKKSQDNSVNFSNSWPLKSFEGL----SKPSPQKKL 868
             + P+   +S       ++P  +SP  ++  ++  S + P  S +      S  SP   L
Sbjct: 4037 KLSPARSTTSGLVG--ESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 4094

Query: 869  ---------VSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRG 919
                     VS++SS    +    ++   P    T  L + P++     G+      P G
Sbjct: 4095 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSP-G 4153

Query: 920  ISLLPDKADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRNS 979
             +        ST  H      +      D++   L E +           HSS  SL  +
Sbjct: 4154 STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAS--------TPTHSSTGSLHTT 4205

Query: 980  AAKKRAKLSG----STSDLESPDSAMKLDLTMDSPSLSSSP-NINSYSESGVYSQESLTS 1034
                 +  +G    ST+    P S+   D T   PS ++ P  +++   S   S  +   
Sbjct: 4206 LTPASSTSTGLQEESTTFQSWPSSS---DTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHF 4262

Query: 1035 SLSTTPQGKRIMSDIFPTFGSKP-------CPTRLSSAKKKISHIAEQSPSAGSSSNPQQ 1087
            S S+T  G+   S+   T  S P        PTR +++      + E + S  SS + + 
Sbjct: 4263 SASSTTLGR---SEESTTVHSSPGATGTALFPTRSATSVL----VGEPTTSPISSGSTET 4315

Query: 1088 ISSFDFTTTKALSEDSVVVVGKGVFGSLSSAPATCSQSVIS 1128
             +    TTT  LSE S            + +PA+ + S +S
Sbjct: 4316 TALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVS 4356



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 76/372 (20%), Positives = 129/372 (34%), Gaps = 33/372 (8%)

Query: 772  TTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTS 831
            +T+ H           S +  T G   E T+ +    + G  + P+   +S       TS
Sbjct: 4247 STTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTS 4306

Query: 832  PLIISPKKS------------QDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGR 879
            P+     ++             + S  F +S P      LS  S     VS++S+    R
Sbjct: 4307 PISSGSTETTALPGSTTTAGLSEKSTTFYSS-PRSPDTTLSPASTTSSGVSEESTTSHSR 4365

Query: 880  NHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEP 939
                ++   P     P + +  ++     G+      P G +        ST  H     
Sbjct: 4366 PGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSP-GSTTASSLGPESTTFHSSPGS 4424

Query: 940  DDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRN--SAAKKRAKLSGSTSDLESP 997
             +      ++    L E +          +HSS  S     S A    +   ST+    P
Sbjct: 4425 TETTLLPDNTTASGLLEAS--------TPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWP 4476

Query: 998  DSAMKLDLTMDSPSLSSS-PNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSK 1056
            +S    D T   P+ +S+   +++ S     S  +   S S+T  G+   S+   T  S 
Sbjct: 4477 NSK---DTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR---SEESTTVHSS 4530

Query: 1057 PCPTRL--SSAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGS 1114
            P  T    S A+   S + E+S +  SS    Q   F  + T +   +           +
Sbjct: 4531 PVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHT 4590

Query: 1115 LSSAPATCSQSV 1126
            +SSAP+T S  V
Sbjct: 4591 ISSAPSTTSALV 4602



 Score = 31.6 bits (70), Expect = 7.0
 Identities = 76/372 (20%), Positives = 129/372 (34%), Gaps = 33/372 (8%)

Query: 772  TTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGAYILPSYPVSSPRTSPKHTS 831
            +T+ H           S +  T G   E T+ +    + G  + P+   +S       TS
Sbjct: 3164 STTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTS 3223

Query: 832  PLIISPKKS------------QDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTGR 879
            P+     ++             + S  F +S P      LS  S     VS++S+    R
Sbjct: 3224 PISSGSTETTALPGSTTTAGLSEKSTTFYSS-PRSPDTTLSPASTTSSGVSEESTTSHSR 3282

Query: 880  NHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKKKEP 939
                ++   P     P + +  ++     G+      P G +        ST  H     
Sbjct: 3283 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP-GSTTASSLGPESTTFHSGPGS 3341

Query: 940  DDIWKCEKDSLPIDLSELNFKDKDLDQEEMHSSLRSLRN--SAAKKRAKLSGSTSDLESP 997
             +      ++    L E +          +HSS  S     S A    +   ST+    P
Sbjct: 3342 TETTLLPDNTTASGLLEAS--------TPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWP 3393

Query: 998  DSAMKLDLTMDSPSLSSS-PNINSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSK 1056
            +S    D T   P+ +S+   +++ S     S  +   S S+T  G+   S+   T  S 
Sbjct: 3394 NSK---DTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR---SEESTTVHSS 3447

Query: 1057 PCPTRL--SSAKKKISHIAEQSPSAGSSSNPQQISSFDFTTTKALSEDSVVVVGKGVFGS 1114
            P  T    S A+   S + E+S +  SS    Q   F  + T +   +           +
Sbjct: 3448 PVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHT 3507

Query: 1115 LSSAPATCSQSV 1126
            +SSAP+T S  V
Sbjct: 3508 ISSAPSTTSALV 3519


>gi|209862971 MAP-kinase activating death domain-containing protein
            isoform a [Homo sapiens]
          Length = 1588

 Score = 40.0 bits (92), Expect = 0.020
 Identities = 60/255 (23%), Positives = 102/255 (40%), Gaps = 35/255 (13%)

Query: 867  KLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDK 926
            +L +QK ++  G +  ENSQE PP++ + +   S S    ++G       P   + + DK
Sbjct: 675  ELQNQKEAEEPGPD-SENSQENPPLRSSSSTTASSSPSTVIHGANSE---PADSTEMDDK 730

Query: 927  ADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFK-----------------DKDLDQEEM 969
            A +         P  I K   D    ++ E + +                 ++D D++  
Sbjct: 731  AAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFPPEEDEDEQGE 790

Query: 970  HSSLRSLRNSAAKKRAKL-------SGSTSDLESPDSAMKLDLTMDSPSLSSSPNINSYS 1022
              + R  ++ +  +  KL         S SD ES   A   + T+ + S      I S++
Sbjct: 791  SYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTSTEGFGGIMSFA 850

Query: 1023 ESGVYSQESLTSSLS--TTP-QGKRIMSDIFPTF--GSKPCPTRLSSAKKKISHIAEQSP 1077
             S +Y   S + SLS  T P +G R  +  FP+     +    + SS  K    +  + P
Sbjct: 851  -SSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKHSPTVKREPP 909

Query: 1078 S-AGSSSNPQQISSF 1091
            S  G SSN  +   F
Sbjct: 910  SPQGRSSNSSENQQF 924


>gi|209571517 MAP-kinase activating death domain-containing protein
            isoform h [Homo sapiens]
          Length = 1587

 Score = 40.0 bits (92), Expect = 0.020
 Identities = 60/255 (23%), Positives = 102/255 (40%), Gaps = 35/255 (13%)

Query: 867  KLVSQKSSDPTGRNHGENSQEKPPVQLTPALVRSPSSRRGLNGTKPVPPIPRGISLLPDK 926
            +L +QK ++  G +  ENSQE PP++ + +   S S    ++G       P   + + DK
Sbjct: 675  ELQNQKEAEEPGPD-SENSQENPPLRSSSSTTASSSPSTVIHGANSE---PADSTEMDDK 730

Query: 927  ADLSTVGHKKKEPDDIWKCEKDSLPIDLSELNFK-----------------DKDLDQEEM 969
            A +         P  I K   D    ++ E + +                 ++D D++  
Sbjct: 731  AAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGSVRRRIYDNPYFEPQYGFPPEEDEDEQGE 790

Query: 970  HSSLRSLRNSAAKKRAKL-------SGSTSDLESPDSAMKLDLTMDSPSLSSSPNINSYS 1022
              + R  ++ +  +  KL         S SD ES   A   + T+ + S      I S++
Sbjct: 791  SYTPRFSQHVSGNRAQKLLRPNSLRLASDSDAESDSRASSPNSTVSNTSTEGFGGIMSFA 850

Query: 1023 ESGVYSQESLTSSLS--TTP-QGKRIMSDIFPTF--GSKPCPTRLSSAKKKISHIAEQSP 1077
             S +Y   S + SLS  T P +G R  +  FP+     +    + SS  K    +  + P
Sbjct: 851  -SSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALVDQKSSVIKHSPTVKREPP 909

Query: 1078 S-AGSSSNPQQISSF 1091
            S  G SSN  +   F
Sbjct: 910  SPQGRSSNSSENQQF 924


>gi|33667044 ABI gene family, member 3 (NESH) binding protein [Homo
            sapiens]
          Length = 1075

 Score = 40.0 bits (92), Expect = 0.020
 Identities = 57/254 (22%), Positives = 88/254 (34%), Gaps = 38/254 (14%)

Query: 815  LPSYPVSSPRTSPKHTSPL------IISPKKSQDNSVNFSNSWPLKSFEGLSKPSPQKKL 868
            +PS P   PR  P  T P        I+PK S+     ++   P K+           + 
Sbjct: 466  IPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKT-----------QF 514

Query: 869  VSQKSSDPTGRNHGENSQEKPPVQLTPALVRSP--SSRRGLNGTKPVPPIPRGISLLPDK 926
            +S K   P      E +  KP  + TP     P  S R  +  T+PVP +P+ ++  P  
Sbjct: 515  ISLKPKIPLSP---EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKT 571

Query: 927  ADLSTVGHKKKEPDDIWKCEKDSLPIDLSE-----------LNFKDKDLDQEEMHSSLRS 975
            +    V +    P D+    K    +  SE           +        QEE+ ++L  
Sbjct: 572  SPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEE 631

Query: 976  LRNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDSPSLSSSPNI-----NSYSESGVYSQE 1030
               S  +        T++L     A     T   P  S  P+I      +   SG     
Sbjct: 632  TDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNV 691

Query: 1031 SLTSSLSTTPQGKR 1044
            S+ S+  T   G R
Sbjct: 692  SVDSTHPTKKPGTR 705


>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
          Length = 1158

 Score = 38.9 bits (89), Expect = 0.044
 Identities = 124/581 (21%), Positives = 217/581 (37%), Gaps = 86/581 (14%)

Query: 694  LKLSQGMPVNDDLCFSRKRVSR-NLFQNSRDFNPDCLPLCAAGTTGTHQTNLSGKCAQLG 752
            ++LS+G    +D   ++KR  R  L + SR        L  + +  + + + S     + 
Sbjct: 609  VELSKG----EDSALAKKRQRRLELLERSRQ------TLEESQSMASWEADSSTASGSIP 658

Query: 753  FSQICGKTGSVGSDLQFLGTTSSHQEKVYASLNFGSKTQQTFGSQTECTSSNGQNPSPGA 812
             S       SV +D    G T+S    V ++ +  S   Q   +   C++SN   P P  
Sbjct: 659  LSAFWSADPSVSAD----GDTTS----VLSTQSHRSHLSQAASNIAGCSTSNPTTPLPNL 710

Query: 813  YILPSYPVSSPRTSPKHTSPLIISPKKSQDNSVNFSNSWPLKSFEGLSKPS----PQKKL 868
             + P   +S         + +  +  + Q+  +  S S  + S + +   S     Q  +
Sbjct: 711  PVGPGDTISIASIQNWIANVVSETLAQKQNEMLLLSRSPSVASMKAVPAASCLGDDQVSM 770

Query: 869  VSQKSSDPTGRNHGENSQEKPPVQLTPAL-----VRSP--SSRRGLNGT-KPVPPIPRGI 920
            +S  SS   G      SQ +P   +   L     + SP  S R  + GT KP+       
Sbjct: 771  LSGHSSSSLGGCLLPQSQARPSSDMQSVLSCNTTLSSPAESCRSKVRGTSKPI------F 824

Query: 921  SLLPDKADLSTVGHKKKEPD-------DIWKCEKDSLPIDLSELNFKDKDLDQEE----- 968
            SL  D  DL  +G K+KE           +K EK +     S L FK K + ++E     
Sbjct: 825  SLFADNVDLKELGRKEKEMQMELREKMSEYKMEKLASDNKRSSL-FKKKKVKEDEDDGVG 883

Query: 969  ---------MHSSLRSLRNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDSPSLSSSPNIN 1019
                     + S   S R+++ K       S +  +   S  ++   MDS       +IN
Sbjct: 884  DGDEDTDSAIGSFRYSSRSNSQKPETDTCSSLAVCDHYASGSRVGKEMDS-------SIN 936

Query: 1020 SYSESGVYSQES--LTSSLSTTPQGKRIMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSP 1077
             +  SG+ ++E     S  S + +GK   S +     SK      SS K   S   EQ  
Sbjct: 937  KWL-SGLRTEEKPPFQSDWSGSSRGKYTRSSLLRETESKS-----SSYKFSKSQSEEQDT 990

Query: 1078 SAGSSSNPQQI-SSFDFTTTKALSEDSVVVVGKGVFGSLSSAPATCSQSVISSVENGDTF 1136
            S+   +N   + S+  F+++       +    +  +   SS+     +         ++ 
Sbjct: 991  SSYHEANGNSVRSTSRFSSSSTREGREMHKFSRSTYNETSSSREESPEPYFFR-RTPESS 1049

Query: 1137 SIKQSIEPPSGIYGRSVQQNISSYLDVENEKDAKVS----ISKSTYNKMRQKRKEEKELF 1192
              ++S EP    + RS       + DVE    +  S      K T + MR + + EKE  
Sbjct: 1050 EREESPEPQRPNWARS-----RDWEDVEESSKSDFSEFGAKRKFTQSFMRSEEEGEKERT 1104

Query: 1193 HNKDCEKKEKNSWERMRHTGTEKMASESETPTGAISQYKER 1233
             N++ E +  +         T++   E       I+ ++ R
Sbjct: 1105 ENRE-EGRFASGRRSQYRRSTDREEEEEMDDEAIIAAWRRR 1144


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 38.9 bits (89), Expect = 0.044
 Identities = 42/194 (21%), Positives = 74/194 (38%), Gaps = 18/194 (9%)

Query: 972  SLRSLRNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDSPSLSSSPNINSYSESGVYSQES 1031
            S+ +   S+       + + S+  +P S        DS + SS  +  + S+S   S E+
Sbjct: 103  SIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEA 162

Query: 1032 LTS------------SLSTTPQGKRIMSDIFPTFGSKPCPTRLSSAKKKISHIAEQSPSA 1079
             T+            S +T  +   + S       S+   T   ++    S     S  A
Sbjct: 163  STATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGA 222

Query: 1080 GSSSNPQQISSFDFTTTKALSEDSVVVVGKGV-----FGSLSSAPATCSQSVISSVENG- 1133
            G+++N +  ++    +T   SE S    G G        + SS   T + S  S+V +G 
Sbjct: 223  GTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGI 282

Query: 1134 DTFSIKQSIEPPSG 1147
             T +  +S  P SG
Sbjct: 283  STVTNSESSTPSSG 296


>gi|20070205 ladinin 1 [Homo sapiens]
          Length = 517

 Score = 38.9 bits (89), Expect = 0.044
 Identities = 62/269 (23%), Positives = 109/269 (40%), Gaps = 34/269 (12%)

Query: 836  SPKKSQDNSVNFSNSWPLKSFEGLSKPSPQKKLVSQKSSDPTG--RNHGENSQEKPPVQL 893
            +P+ SQ+     S S  L S E    P P       +  D     R   E  Q +  V+ 
Sbjct: 45   APRLSQNGDRQASASERLPSVEEAEVPKPLPPASKDEDEDIQSILRTRQERRQRRQVVEA 104

Query: 894  TPALVRSP-SSRRGLNGTKPVPPIPRGISLLPDKADLSTVGHKK--KEPDDIWKCEKDSL 950
              A ++    +  G N   PV    +    L  K +L     ++  +E    W  E++SL
Sbjct: 105  AQAPIQERLEAEEGRNSLSPVQATQKP---LVSKKELEIPPRRRLSREQRGPWALEEESL 161

Query: 951  PIDLSELNFKDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSTSDLESPDSAMKLDLTMDSP 1010
                 E   + K + ++       S+    A +++ +S  TS  E   ++ K  L   S 
Sbjct: 162  VG--REPEERKKGVPEKSPVLEKSSMPKKTAPEKSLVSDKTSISEKVLASEKTSL---SE 216

Query: 1011 SLSSSPNINSYSESGVYSQESLTSSLSTTP-----QGKRIMSD---IF---------PTF 1053
             ++ S   NS  +  V  + S+ S  S  P      G+R++S+   IF         PT 
Sbjct: 217  KIAVSEKRNSSEKKSVLEKTSV-SEKSLAPGMALGSGRRLVSEKASIFEKALASEKSPTA 275

Query: 1054 GSKPCPTRLSSAKKKISHIAEQSPSAGSS 1082
             +KP P R +++++    +A++ P++G S
Sbjct: 276  DAKPAPKRATASEQP---LAQEPPASGGS 301


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,876,373
Number of Sequences: 37866
Number of extensions: 3098151
Number of successful extensions: 10275
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 202
Number of HSP's that attempted gapping in prelim test: 9716
Number of HSP's gapped (non-prelim): 721
length of query: 1720
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1604
effective length of database: 13,855,062
effective search space: 22223519448
effective search space used: 22223519448
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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