Guide to the Human Genome
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Name: MADD Sequence: fasta or formatted (1588aa) NCBI GI: 209862971
Description:

MAP-kinase activating death domain-containing protein isoform a

Referenced in:

Additional Interaction Domain Families
TNF and Related Signals

Other entries for this name:
alt prot [1581aa] MAP-kinase activating death domain-containing protein isoform g
alt prot [1587aa] MAP-kinase activating death domain-containing protein isoform h
alt prot [1565aa] MAP-kinase activating death domain-containing protein isoform b
alt prot [1545aa] MAP-kinase activating death domain-containing protein isoform c
alt prot [1608aa] MAP-kinase activating death domain-containing protein isoform e
alt prot [1479aa] MAP-kinase activating death domain-containing protein isoform f
alt prot [1647aa] MAP-kinase activating death domain-containing protein isoform d
alt prot [1544aa] MAP-kinase activating death domain-containing protein isoform i
alt prot [1541aa] MAP-kinase activating death domain-containing protein isoform j
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.4         86           3
 C cysteine            1.4         23           2
 D aspartate           6.0         95           2
 E glutamate           7.1        112           2
 F phenylalanine       3.7         58           2
 G glycine             6.2         99           2
 H histidine           2.1         33           1
 I isoleucine          3.8         60           2
 K lysine              5.2         83           3
 L leucine            10.2        162           3
 M methionine          2.4         38           2
 N asparagine          3.6         57           2
 P proline             6.4        101           2
 Q glutamine           4.2         66           2
 R arginine            6.1         97           3
 S serine             11.0        175           4
 T threonine           5.0         79           2
 V valine              6.9        109           2
 W tryptophan          0.8         12           2
 Y tyrosine            2.7         43           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   MAP-kinase activating death domain-containing prote... 
MADD                  0.998   MAP-kinase activating death domain-containing prote...
MADD                  0.996   MAP-kinase activating death domain-containing prote...
MADD                  0.988   MAP-kinase activating death domain-containing prote...
MADD                  0.964   MAP-kinase activating death domain-containing prote...
MADD                  0.962   MAP-kinase activating death domain-containing prote...
MADD                  0.960   MAP-kinase activating death domain-containing prote...
MADD                  0.960   MAP-kinase activating death domain-containing prote...
MADD                  0.941   MAP-kinase activating death domain-containing protei...
MADD                  0.917   MAP-kinase activating death domain-containing prote...
SBF1                  0.025   SET binding factor 1 
DENND4A               0.021   DENN/MADD domain containing 4A isoform 1 
DENND4A               0.021   DENN/MADD domain containing 4A isoform 2 
DENND4B               0.019   DENN/MADD domain containing 4B 
DENND4C               0.017   DENN/MADD domain containing 4C 
DENND5B               0.017   DENN/MADD domain containing 5B 
SBF2                  0.017   SET binding factor 2 
DENND5A               0.015   RAB6 interacting protein 1 
DENND3                0.015   DENN/MADD domain containing 3 
ST5                   0.012   suppression of tumorigenicity 5 isoform 1 
ST5                   0.012   suppression of tumorigenicity 5 isoform 1 
ST5                   0.012   suppression of tumorigenicity 5 isoform 2 
DENND2C               0.011   DENN/MADD domain containing 2C 
DENND2A               0.011   DENN/MADD domain containing 2A 
DENND1C               0.011   DENN/MADD domain containing 1C 
DSPP                  0.010   dentin sialophosphoprotein preproprotein 
DENND1B               0.010   DENN/MADD domain containing 1B isoform 2 
DENND1B               0.009   DENN/MADD domain containing 1B isoform 1 
DENND2D               0.008   DENN/MADD domain containing 2D 
DENND1A               0.008   DENN/MADD domain containing 1A isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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