BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|9257240 neuroplastin isoform a precursor [Homo sapiens] (282 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|9257240 neuroplastin isoform a precursor [Homo sapiens] 573 e-164 gi|238624149 neuroplastin isoform d precursor [Homo sapiens] 558 e-159 gi|6912646 neuroplastin isoform b precursor [Homo sapiens] 518 e-147 gi|238624147 neuroplastin isoform c precursor [Homo sapiens] 503 e-142 gi|38372919 basigin isoform 1 precursor [Homo sapiens] 176 2e-44 gi|38372925 basigin isoform 2 precursor [Homo sapiens] 176 2e-44 gi|38372923 basigin isoform 4 [Homo sapiens] 161 5e-40 gi|38348215 embigin [Homo sapiens] 69 5e-12 gi|110349719 titin isoform N2-A [Homo sapiens] 69 6e-12 gi|109150416 peroxidasin [Homo sapiens] 67 1e-11 gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 60 3e-09 gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 60 3e-09 gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 57 2e-08 gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 57 2e-08 gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 57 2e-08 gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 55 5e-08 gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 55 5e-08 gi|118572606 hemicentin 1 [Homo sapiens] 55 7e-08 gi|126517478 peroxidasin homolog-like [Homo sapiens] 55 7e-08 gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 55 9e-08 gi|45594240 limbic system-associated membrane protein [Homo sapi... 54 1e-07 gi|19743806 roundabout 1 isoform b [Homo sapiens] 54 2e-07 gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 54 2e-07 gi|4506569 roundabout 1 isoform a [Homo sapiens] 54 2e-07 gi|134244585 putative neuronal cell adhesion molecule [Homo sapi... 54 2e-07 gi|110349717 titin isoform novex-2 [Homo sapiens] 53 3e-07 gi|110349713 titin isoform novex-1 [Homo sapiens] 53 3e-07 gi|110349715 titin isoform N2-B [Homo sapiens] 53 3e-07 gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 53 3e-07 gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 52 4e-07 >gi|9257240 neuroplastin isoform a precursor [Homo sapiens] Length = 282 Score = 573 bits (1478), Expect = e-164 Identities = 282/282 (100%), Positives = 282/282 (100%) Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS 60 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS 60 Query: 61 HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA 120 HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA Sbjct: 61 HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA 120 Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN Sbjct: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI 240 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI Sbjct: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI 240 Query: 241 IVVYEKRKRPDEVPDDDEPAGPMKTNSTNNHKDKNLRQRNTN 282 IVVYEKRKRPDEVPDDDEPAGPMKTNSTNNHKDKNLRQRNTN Sbjct: 241 IVVYEKRKRPDEVPDDDEPAGPMKTNSTNNHKDKNLRQRNTN 282 >gi|238624149 neuroplastin isoform d precursor [Homo sapiens] Length = 278 Score = 558 bits (1439), Expect = e-159 Identities = 278/282 (98%), Positives = 278/282 (98%), Gaps = 4/282 (1%) Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS 60 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSS 60 Query: 61 HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA 120 HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA Sbjct: 61 HTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA 120 Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN Sbjct: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI 240 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI Sbjct: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVI 240 Query: 241 IVVYEKRKRPDEVPDDDEPAGPMKTNSTNNHKDKNLRQRNTN 282 IVVYEKRKRPDEVPD AGPMKTNSTNNHKDKNLRQRNTN Sbjct: 241 IVVYEKRKRPDEVPD----AGPMKTNSTNNHKDKNLRQRNTN 278 >gi|6912646 neuroplastin isoform b precursor [Homo sapiens] Length = 398 Score = 518 bits (1333), Expect = e-147 Identities = 251/252 (99%), Positives = 252/252 (100%) Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90 +PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN Sbjct: 147 KPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 206 Query: 91 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 150 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH Sbjct: 207 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266 Query: 151 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS Sbjct: 267 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326 Query: 211 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNSTNN 270 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNSTNN Sbjct: 327 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNSTNN 386 Query: 271 HKDKNLRQRNTN 282 HKDKNLRQRNTN Sbjct: 387 HKDKNLRQRNTN 398 Score = 66.2 bits (160), Expect = 3e-11 Identities = 76/235 (32%), Positives = 96/235 (40%), Gaps = 52/235 (22%) Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVT--SEEVIIRDSPVLPVTLQCNLTS 58 MSGSSLPSALALSLLLVSGSLLPGPGAAQN + + SE + D+ L C++ Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDA----FELYCDVVG 56 Query: 59 S-SHTLTYSYWTKNGVEL-------SATRKNASNMEY--------RINKPRAEDSGEYHC 102 S + + + Y N E + R+ N Y RI + EDSG Y C Sbjct: 57 SPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYEC 116 Query: 103 VYHFVSAPKAN--------------ATIEVKAAPDI-TGHKRSENKNEGQDATMYCKSVG 147 + PK N ATI V P I T + + T+ C Sbjct: 117 --RASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTS 174 Query: 148 YPHPDWIWRKKENGMPMDIV--NTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200 H +NG+ + N S + INK ED GEY C Sbjct: 175 SSHTLTYSYWTKNGVELSATRKNASNMEYRINKPR-----------AEDSGEYHC 218 Score = 30.4 bits (67), Expect = 1.8 Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 7/82 (8%) Query: 130 SENKNEGQDATMYCKSVGYPHPDWIWRKKENGMP---MDIVNTSGRFFIINKENYTELNI 186 SE K G +YC VG P P+ W E + + + + + Y + Sbjct: 39 SETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGV 98 Query: 187 VNLQIT----EDPGEYECNATN 204 L+IT ED G YEC A+N Sbjct: 99 SVLRITRLTLEDSGTYECRASN 120 >gi|238624147 neuroplastin isoform c precursor [Homo sapiens] Length = 394 Score = 503 bits (1294), Expect = e-142 Identities = 247/252 (98%), Positives = 248/252 (98%), Gaps = 4/252 (1%) Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90 +PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN Sbjct: 147 KPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 206 Query: 91 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 150 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH Sbjct: 207 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266 Query: 151 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS Sbjct: 267 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326 Query: 211 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNSTNN 270 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPD AGPMKTNSTNN Sbjct: 327 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPD----AGPMKTNSTNN 382 Query: 271 HKDKNLRQRNTN 282 HKDKNLRQRNTN Sbjct: 383 HKDKNLRQRNTN 394 Score = 66.2 bits (160), Expect = 3e-11 Identities = 76/235 (32%), Positives = 96/235 (40%), Gaps = 52/235 (22%) Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVT--SEEVIIRDSPVLPVTLQCNLTS 58 MSGSSLPSALALSLLLVSGSLLPGPGAAQN + + SE + D+ L C++ Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDA----FELYCDVVG 56 Query: 59 S-SHTLTYSYWTKNGVEL-------SATRKNASNMEY--------RINKPRAEDSGEYHC 102 S + + + Y N E + R+ N Y RI + EDSG Y C Sbjct: 57 SPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYEC 116 Query: 103 VYHFVSAPKAN--------------ATIEVKAAPDI-TGHKRSENKNEGQDATMYCKSVG 147 + PK N ATI V P I T + + T+ C Sbjct: 117 --RASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTS 174 Query: 148 YPHPDWIWRKKENGMPMDIV--NTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200 H +NG+ + N S + INK ED GEY C Sbjct: 175 SSHTLTYSYWTKNGVELSATRKNASNMEYRINKPR-----------AEDSGEYHC 218 Score = 30.4 bits (67), Expect = 1.8 Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 7/82 (8%) Query: 130 SENKNEGQDATMYCKSVGYPHPDWIWRKKENGMP---MDIVNTSGRFFIINKENYTELNI 186 SE K G +YC VG P P+ W E + + + + + Y + Sbjct: 39 SETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGV 98 Query: 187 VNLQIT----EDPGEYECNATN 204 L+IT ED G YEC A+N Sbjct: 99 SVLRITRLTLEDSGTYECRASN 120 >gi|38372919 basigin isoform 1 precursor [Homo sapiens] Length = 385 Score = 176 bits (447), Expect = 2e-44 Identities = 95/237 (40%), Positives = 142/237 (59%), Gaps = 8/237 (3%) Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSA 109 + L C+L S+ +T W K GV L E++++ + GEY CV F+ Sbjct: 153 ILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPE 208 Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVN 168 P A I++ P + K SE+ NEG+ A + CKS P DW W K + ++N Sbjct: 209 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN 268 Query: 169 TS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPF 227 S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + LRVRSHLA LWPF Sbjct: 269 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPF 328 Query: 228 LGILAEIIILVVIIVVYEKRKRPDEVPDDDEP-AGPMKTNSTN-NHKDKNLRQRNTN 282 LGI+AE+++LV II +YEKR++P++V DDD+ + P+K++ + N K KN+RQRN++ Sbjct: 329 LGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 385 Score = 28.5 bits (62), Expect = 6.9 Identities = 19/86 (22%), Positives = 37/86 (43%), Gaps = 15/86 (17%) Query: 130 SENKNEGQDATMYCKSVGYPHPDWIW-----------RKKENGMPMDIVNTSGRFFIINK 178 S+ + G ++C++VG P P+ W + +G +D V+ + Sbjct: 31 SQQRWVGGSVELHCEAVGSPVPEIQWWFEGQGPNDTCSQLWDGARLDRVHIHATYH---- 86 Query: 179 ENYTELNIVNLQITEDPGEYECNATN 204 ++ ++ + ED G YEC A+N Sbjct: 87 QHAASTISIDTLVEEDTGTYECRASN 112 >gi|38372925 basigin isoform 2 precursor [Homo sapiens] Length = 269 Score = 176 bits (447), Expect = 2e-44 Identities = 95/237 (40%), Positives = 142/237 (59%), Gaps = 8/237 (3%) Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSA 109 + L C+L S+ +T W K GV L E++++ + GEY CV F+ Sbjct: 37 ILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPE 92 Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVN 168 P A I++ P + K SE+ NEG+ A + CKS P DW W K + ++N Sbjct: 93 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN 152 Query: 169 TS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPF 227 S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + LRVRSHLA LWPF Sbjct: 153 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPF 212 Query: 228 LGILAEIIILVVIIVVYEKRKRPDEVPDDDEP-AGPMKTNSTN-NHKDKNLRQRNTN 282 LGI+AE+++LV II +YEKR++P++V DDD+ + P+K++ + N K KN+RQRN++ Sbjct: 213 LGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 269 >gi|38372923 basigin isoform 4 [Homo sapiens] Length = 205 Score = 161 bits (408), Expect = 5e-40 Identities = 84/189 (44%), Positives = 122/189 (64%), Gaps = 6/189 (3%) Query: 98 GEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWR 156 GEY CV F+ P A I++ P + K SE+ NEG+ A + CKS P DW W Sbjct: 19 GEYSCV--FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWY 76 Query: 157 KKENGMPMDIVNTS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 215 K + ++N S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + L Sbjct: 77 KITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 136 Query: 216 RVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEP-AGPMKTNSTN-NHKD 273 RVRSHLA LWPFLGI+AE+++LV II +YEKR++P++V DDD+ + P+K++ + N K Sbjct: 137 RVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKG 196 Query: 274 KNLRQRNTN 282 KN+RQRN++ Sbjct: 197 KNVRQRNSS 205 >gi|38348215 embigin [Homo sapiens] Length = 327 Score = 68.9 bits (167), Expect = 5e-12 Identities = 63/242 (26%), Positives = 101/242 (41%), Gaps = 17/242 (7%) Query: 50 VTLQCNLTSSSHTLTYSY-WTKNGVEL------SATRKNASNMEYRINKPRAEDSGEYHC 102 V L C T+S + W K+G +L SAT +YR ++ G Y C Sbjct: 84 VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYT-QYRFTIINSKQMGSYSC 142 Query: 103 VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 162 + + +V P++ G + G + CK +W W NG Sbjct: 143 FFREEKEQRGTFNFKV---PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSS-NGS 198 Query: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE-YECNATNAIGSASVVTVLRVRSHL 221 V ++IN E + Q+ E+ GE Y C A +G + L V S+L Sbjct: 199 VKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYL 258 Query: 222 APLWPFLGILAEIIILVVIIVVYE----KRKRPDEVPDDDEPAGPMKTNSTNNHKDKNLR 277 PL PFL I+AE+I+LV I++ E K+K+ + + E +K++ +N ++ R Sbjct: 259 VPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQIEQLKSDDSNGIENNVPR 318 Query: 278 QR 279 R Sbjct: 319 HR 320 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 68.6 bits (166), Expect = 6e-12 Identities = 53/167 (31%), Positives = 76/167 (45%), Gaps = 18/167 (10%) Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEY-------RINKPRAEDSGEYHC 102 + L+C ++ S W +N EL + K NM + IN+ AEDSG+Y C Sbjct: 6382 IQLECKISGSPEIKVS--WFRNDSELHESWKY--NMSFINSVALLTINEASAEDSGDYIC 6437 Query: 103 VYHF-VSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161 H V + + VKA P T +G D + C+ G P + +W K Sbjct: 6438 EAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQ 6497 Query: 162 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 208 V S +F I +K T L+I+NL+ + D GEY C ATN +GS Sbjct: 6498 -----VRNSKKFKITSKHFDTSLHILNLEAS-DVGEYHCKATNEVGS 6538 Score = 54.3 bits (129), Expect = 1e-07 Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 13/129 (10%) Query: 95 EDSGEYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP--HP 151 EDSG+Y C H + +++T ++VK P +G D + C+ G P H Sbjct: 7371 EDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHV 7430 Query: 152 DWIWRKKENGMPMDIVNTSGRFFIINKENY-TELNIVNLQITEDPGEYECNATNAIGSAS 210 W K+E SG+ + I EN+ T ++I+N+ D GEY+C ATN +GS + Sbjct: 7431 SWYKDKREL--------RSGKKYKIMSENFLTSIHILNVDAA-DIGEYQCKATNDVGSDT 7481 Query: 211 VVTVLRVRS 219 V + +++ Sbjct: 7482 CVGSIALKA 7490 Score = 53.5 bits (127), Expect = 2e-07 Identities = 41/173 (23%), Positives = 78/173 (45%), Gaps = 14/173 (8%) Query: 52 LQCNLTSSSHTLTYSYWTKNGVELSATRKNA-----SNMEYRINKPRAEDSGEYHC-VYH 105 L+C + S W +N EL A+ K S ++N EDSG++ C + Sbjct: 5443 LECKIAGSPEIRVV--WFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQN 5500 Query: 106 FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMD 165 + + + VK P + + + ++ C+ G P + +W K + + Sbjct: 5501 PAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQL--- 5557 Query: 166 IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 +S ++ I +K +T ++I+N+ T D GEY C A N +GS + V ++++ Sbjct: 5558 --RSSKKYKIASKNFHTSIHILNVD-TSDIGEYHCKAQNEVGSDTCVCTVKLK 5607 Score = 53.1 bits (126), Expect = 3e-07 Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 16/160 (10%) Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATI--E 117 W NGVEL+ + + + S+ I + D G C+ + + + T+ E Sbjct: 33070 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE 33129 Query: 118 VKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIIN 177 + AP RS+N NEGQ+ C+ G P P+ W K N +P+ I S I Sbjct: 33130 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK--NNLPISI---SSNVSISR 33184 Query: 178 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 N L I N ++ D G+Y A N G S L V Sbjct: 33185 SRNVYSLEIRNASVS-DSGKYTIKAKNFRGQCSATASLMV 33223 Score = 49.3 bits (116), Expect = 4e-06 Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 12/162 (7%) Query: 68 WTKNGVELSATRK-NASNME----YRINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAA 121 W KNG+ ++ +++ N + E I ED+G+Y+C S + +A I + Sbjct: 7901 WKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEP 7960 Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181 P + G A++ C+ G P W K + + T+ + N Sbjct: 7961 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRP---TTTYKMHFRNNVAT 8017 Query: 182 TELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223 N V++ D GEY C A N++G S T L V+ P Sbjct: 8018 LVFNQVDIN---DSGEYICKAENSVGEVSASTFLTVQEQKLP 8056 Score = 48.9 bits (115), Expect = 5e-06 Identities = 50/197 (25%), Positives = 77/197 (39%), Gaps = 17/197 (8%) Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90 EP + + I+ + TL+C + + T W K+G EL++ K + +++ Sbjct: 7584 EPATIVEKPESIKVTTGDTCTLECTVAGTPELSTK--WFKDGKELTSDNKYKISFFNKVS 7641 Query: 91 KPRA-----EDSGEYHC-VYHFVSAPKANATIEVK---AAPDITGHKRSENKNEGQDATM 141 + DSG Y V + V A+++V P T + N G M Sbjct: 7642 GLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVM 7701 Query: 142 YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECN 201 CK G P W + N + +SGR + + T VN+ D G+Y C Sbjct: 7702 ECKVYGSPPISVSWFHEGNEI------SSGRKYQTTLTDNTCALTVNMLEESDSGDYTCI 7755 Query: 202 ATNAIGSASVVTVLRVR 218 ATN GS L VR Sbjct: 7756 ATNMAGSDECSAPLTVR 7772 Score = 47.8 bits (112), Expect = 1e-05 Identities = 47/206 (22%), Positives = 88/206 (42%), Gaps = 30/206 (14%) Query: 26 GAAQNEPRIVTSE--EVIIRDSPVLPV------TLQCNLTSSSHTLTYSYWTKNGVELSA 77 G A ++ + E + I + SPVL + T +C +T + W +G E++A Sbjct: 4847 GTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVS--WYLDGNEITA 4904 Query: 78 TRKNASNM-----EYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSE 131 +K+ + ++I+ R E+SG Y C + + ++VK P + Sbjct: 4905 IQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPV 4964 Query: 132 NKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQI 191 + D + C+ G P + W K + +S ++ + ++ +++ NL I Sbjct: 4965 EVVKYSDVELECEVTGTPPFEVTWLKNNRE-----IRSSKKYTLTDR-----VSVFNLHI 5014 Query: 192 TE----DPGEYECNATNAIGSASVVT 213 T+ D GEY+C +N GS S T Sbjct: 5015 TKCDPSDTGEYQCIVSNEGGSCSCST 5040 Score = 47.0 bits (110), Expect = 2e-05 Identities = 42/158 (26%), Positives = 67/158 (42%), Gaps = 13/158 (8%) Query: 68 WTKNGVELSATRKNASNMEYRINK-----PRAEDSGEYHCVY-HFVSAPKANATIEVKAA 121 W+K+G +L + E +I + +DSG Y C + + +AT+ V+ Sbjct: 3677 WSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREP 3736 Query: 122 PDITGH-KRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 P S G+ A ++CK G P W K N + NT R + +N E Sbjct: 3737 PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFK--NNKELSESNTV-RMYFVNSEA 3793 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 ++ V + ED G Y C A N +GS S T + ++ Sbjct: 3794 ILDITDVKV---EDSGSYSCEAVNDVGSDSCSTEIVIK 3828 Score = 46.2 bits (108), Expect = 3e-05 Identities = 50/213 (23%), Positives = 86/213 (40%), Gaps = 31/213 (14%) Query: 26 GAAQNEPRIVTSEEVIIRDSPVLPV----------TLQCNLTSSSHTLTYSYWTKNGVEL 75 G A + +++ SE + + PV T +C++T ++ W K+ E+ Sbjct: 7195 GTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKIT--WAKDNREI 7252 Query: 76 --------SATRKNASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITG 126 + A+ ++ K D+G+Y C + +A + V+ P Sbjct: 7253 RPGGNYKMTLVENTATLTVLKVGKG---DAGQYTCYASNIAGKDSCSAQLGVQEPPRFIK 7309 Query: 127 HKRSENKNEGQDATMY-CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELN 185 + + T Y CK G P +W K E + S +F + ++ L Sbjct: 7310 KLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETE-----IQESSKFRMSFVDSVAVLE 7364 Query: 186 IVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 + NL + ED G+Y C A NA GSAS T L+V+ Sbjct: 7365 MHNLSV-EDSGDYTCEAHNAAGSASSSTSLKVK 7396 Score = 45.1 bits (105), Expect = 7e-05 Identities = 37/134 (27%), Positives = 60/134 (44%), Gaps = 8/134 (5%) Query: 88 RINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGH-KRSENKNEGQDATMYCKS 145 RI K DSG+Y C + V +A + VK P + S+ +G+ + CK Sbjct: 6329 RILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKI 6388 Query: 146 VGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNA 205 G P W + ++ + + S ++ + + N L +N ED G+Y C A N Sbjct: 6389 SGSPEIKVSWFRNDSEL-----HESWKYNM-SFINSVALLTINEASAEDSGDYICEAHNG 6442 Query: 206 IGSASVVTVLRVRS 219 +G AS T L V++ Sbjct: 6443 VGDASCSTALTVKA 6456 Score = 44.7 bits (104), Expect = 9e-05 Identities = 39/162 (24%), Positives = 59/162 (36%), Gaps = 12/162 (7%) Query: 68 WTKNGVELSATRK-NASNME----YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAA 121 W K+G ++ + K N E I D+G+Y C + + A + Sbjct: 6019 WKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEP 6078 Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181 P G ++ C+ G P W K + + R + N Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRP---TPEYRTYFTNNVAT 6135 Query: 182 TELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223 N VN+ D GEY C A N+IG+AS TV R++ P Sbjct: 6136 LVFNKVNIN---DSGEYTCKAENSIGTASSKTVFRIQERQLP 6174 Score = 43.9 bits (102), Expect = 2e-04 Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 20/152 (13%) Query: 68 WTKNGVELSATRKNA-----SNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAA 121 W N E+ + K+ S R+ EDSGEY C + + ++ + VK + Sbjct: 4333 WFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKES 4392 Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181 P T + + D + + G P + W K + SGR + + + Sbjct: 4393 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNT------ILRSGRKY----KTF 4442 Query: 182 TELNIVNLQITE----DPGEYECNATNAIGSA 209 + ++V+LQI + D GEY+C TN +GS+ Sbjct: 4443 IQDHLVSLQILKFVAADAGEYQCRVTNEVGSS 4474 Score = 43.5 bits (101), Expect = 2e-04 Identities = 47/206 (22%), Positives = 80/206 (38%), Gaps = 29/206 (14%) Query: 20 SLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATR 79 S L PG Q P + I++ +P + W K+ VEL + Sbjct: 5331 SFLVKPGRQQAIPDSTVEFKAILKGTPPFKIK----------------WFKDDVELVSGP 5374 Query: 80 KNASNME-----YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGH-KRSEN 132 K +E + A +G+Y C V + V + + V P + S+ Sbjct: 5375 KCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKI 5434 Query: 133 KNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT 192 G + + CK G P +W + E+ +P S ++ + ++ + + NL T Sbjct: 5435 VKAGDSSRLECKIAGSPEIRVVWFRNEHELP-----ASDKYRMTFIDSVAVIQMNNLS-T 5488 Query: 193 EDPGEYECNATNAIGSASVVTVLRVR 218 ED G++ C A N GS S T + V+ Sbjct: 5489 EDSGDFICEAQNPAGSTSCSTKVIVK 5514 Score = 41.2 bits (95), Expect = 0.001 Identities = 41/162 (25%), Positives = 66/162 (40%), Gaps = 14/162 (8%) Query: 52 LQCNLTSSSHTLTYSYWTKNGVELSAT---RKNASNME--YRINKPRAEDSGEYHC-VYH 105 L C L S + W KN ELS + R N E I + EDSG Y C + Sbjct: 3757 LHCKLKGSP--VIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVN 3814 Query: 106 FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMD 165 V + + I +K P + G +A + C+ G + W K + Sbjct: 3815 DVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQ---- 3870 Query: 166 IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207 + +S ++ + ++++ L I + + D GEYEC N +G Sbjct: 3871 -IRSSKKYRLFSQKSLVCLEIFSFN-SADVGEYECVVANEVG 3910 Score = 40.8 bits (94), Expect = 0.001 Identities = 42/150 (28%), Positives = 62/150 (41%), Gaps = 16/150 (10%) Query: 68 WTKNGVELSATRK-NASNMEY----RINKPRAEDSGEYHCV----YHFVSAPKANATIEV 118 W K G E+ + K + + +Y I + + D GEY C Y VS A T+ Sbjct: 3489 WFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCT-ATLTVTE 3547 Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178 P +S G+ A C G P + IW+K + + S + I + Sbjct: 3548 AYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAAL-----SPSPNWRISDA 3602 Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGS 208 EN L + NL I +D G Y C A+N G+ Sbjct: 3603 ENKHILELSNLTI-QDRGVYSCKASNKFGA 3631 Score = 40.8 bits (94), Expect = 0.001 Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 18/159 (11%) Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAA 121 W K+G E+S + K + ++ +N ED+ Y C V+ A + + VK Sbjct: 5270 WFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEP 5329 Query: 122 PDITGHKRSENKNEGQDATMYCKSV--GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 179 P + + D+T+ K++ G P W K D+ SG I E Sbjct: 5330 PSFL--VKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKD------DVELVSGPKCFIGLE 5381 Query: 180 NYTE-LNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 T LN+ ++ ++ G+Y C+ TN +GS S T+L V Sbjct: 5382 GSTSFLNLYSVDASKT-GQYTCHVTNDVGSDSCTTMLLV 5419 Score = 40.4 bits (93), Expect = 0.002 Identities = 51/187 (27%), Positives = 75/187 (40%), Gaps = 19/187 (10%) Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME---- 86 EP +T E V I + P TLQ + + + W K+G EL+ K ++ Sbjct: 4577 EPATITEEAVSIDVTQGDPATLQVKFSGTKEIT--AKWFKDGQELTLGSKYKISVTDTVS 4634 Query: 87 -YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVK---AAPDITGHKRSENKNEGQDATM 141 +I +DSGEY V + V A I V P T + + +G + Sbjct: 4635 ILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDL 4694 Query: 142 YCKSVGYPHPDWI-WRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200 C G HP I W K + ++ S ++ +N L I L+ T D G Y C Sbjct: 4695 ECIVAG-SHPISIQWFKDDQE-----ISASEKYKFSFHDNTAFLEISQLEGT-DSGTYTC 4747 Query: 201 NATNAIG 207 +ATN G Sbjct: 4748 SATNKAG 4754 Score = 39.7 bits (91), Expect = 0.003 Identities = 42/178 (23%), Positives = 70/178 (39%), Gaps = 17/178 (9%) Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRI-----NKPRAEDSGEYHCVY 104 V+LQC + + +T S W K +L T + + + NK DSGEY C Sbjct: 6096 VSLQCQVAGTPE-ITVS-WYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKA 6153 Query: 105 HFVSAPKANATI----EVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKEN 160 ++ T+ E + P + + G T+ C+ G W + + Sbjct: 6154 ENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYR-DG 6212 Query: 161 GMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 + D N F +N L I+ ++ G+Y C+A+N +G+AS L R Sbjct: 6213 VLLRDDENLQTSFV----DNVATLKILQTDLSHS-GQYSCSASNPLGTASSSARLTAR 6265 Score = 39.7 bits (91), Expect = 0.003 Identities = 40/181 (22%), Positives = 73/181 (40%), Gaps = 14/181 (7%) Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCV 103 P+ L+ T + ++ S W K+ +S + + + M + I + ED +Y C+ Sbjct: 6943 PIVLEATYTGTP-PISVS-WIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCL 7000 Query: 104 YHFVSAPK-ANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 162 + A + V P G+ AT+ CK G P W K+ + Sbjct: 7001 IENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKL 7060 Query: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLA 222 ++ + + K N L ++N D GEY C A N++G+ + VL +++ Sbjct: 7061 -----RSAPAYKMQFKNNVASL-VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKL 7114 Query: 223 P 223 P Sbjct: 7115 P 7115 Score = 39.7 bits (91), Expect = 0.003 Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 14/160 (8%) Query: 68 WTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCVY-HFVSAPKANATIEVKAA 121 W + G EL +RK + + R + ED G Y C+ + V + ++ + ++A Sbjct: 30566 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQAT 30625 Query: 122 PDI-TGHKRSENKNEGQDATM--YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178 P G+ E +T+ + +G P P W + ++ S I N Sbjct: 30626 PQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-----LLQNSENITIENT 30680 Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 E+YT L + N+Q G+Y+ +N G+ + + ++ Sbjct: 30681 EHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 30720 Score = 39.3 bits (90), Expect = 0.004 Identities = 30/114 (26%), Positives = 58/114 (50%), Gaps = 16/114 (14%) Query: 38 EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINK-----P 92 ++V +++ +T Q ++ + S W +NG L ++ + +E++++K Sbjct: 8752 QDVTLKEGQTCTMTCQFSVPNVK-----SEWFRNGRILKPQGRHKTEVEHKVHKLTIADV 8806 Query: 93 RAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSEN--KNEGQDATMYCK 144 RAED G+Y C Y + + +A + ++A P I KR +N +E Q AT C+ Sbjct: 8807 RAEDQGQYTCKYEDL---ETSAELRIEAEP-IQFTKRIQNIVVSEHQSATFECE 8856 Score = 38.9 bits (89), Expect = 0.005 Identities = 49/197 (24%), Positives = 76/197 (38%), Gaps = 31/197 (15%) Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYR-------INKPRAEDSGEYH 101 P TLQC + + W K +L + A M+++ INK D GEY Sbjct: 7036 PATLQCKVDGTPEIRIS--WYKEHTKLRSAP--AYKMQFKNNVASLVINKVDHSDVGEYS 7091 Query: 102 C-VYHFVSAPKANATIEVKAA---PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRK 157 C + V A ++A + +KA P + ++ G C+ G W K Sbjct: 7092 CKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYK 7151 Query: 158 KENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDP----GEYECNATNAIGSASVVT 213 + + D N F N+ LQI + G+Y C+A+N +G+AS Sbjct: 7152 -DGVLLKDDANLQTSFVH---------NVATLQILQTDQSHIGQYNCSASNPLGTASSSA 7201 Query: 214 VLRVRSHLAPLWPFLGI 230 L + H P PF + Sbjct: 7202 KLILSEHEVP--PFFDL 7216 Score = 38.5 bits (88), Expect = 0.007 Identities = 47/178 (26%), Positives = 73/178 (41%), Gaps = 20/178 (11%) Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVEL-------SATRKNASNMEYRINKPRAEDSGEYHC 102 V L+C ++ S+ W ++G E+ S+ +N + + +P D+G Y C Sbjct: 6758 VVLECRVSGSAPISVG--WFQDGNEIVSGPKCQSSFSENVCTLNLSLLEP--SDTGIYTC 6813 Query: 103 VYHFVS-APKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161 V V+ + + +A + V+ P S G T G P W K Sbjct: 6814 VAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRE 6873 Query: 162 M-PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 + P + N S F+ TEL + +Q E G+Y C TN GSAS T L V+ Sbjct: 6874 LVPGESCNISLEDFV------TELELFEVQPLES-GDYSCLVTNDAGSASCTTHLFVK 6924 Score = 38.1 bits (87), Expect = 0.009 Identities = 27/110 (24%), Positives = 46/110 (41%), Gaps = 15/110 (13%) Query: 114 ATIEVKAAPD-ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK----ENGMPMDIVN 168 A +E+ P + ++ EG+ T+ C GYP P W ++ E+ + I Sbjct: 934 APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 993 Query: 169 TSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 SG ++ +E + ED G + C+A N G+ S L V+ Sbjct: 994 QSGIARLMIREAF----------AEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033 Score = 38.1 bits (87), Expect = 0.009 Identities = 44/195 (22%), Positives = 77/195 (39%), Gaps = 25/195 (12%) Query: 42 IRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME---------YRINKP 92 ++++ LPV C + S S ++ S W K+G L K++ N++ I K Sbjct: 8066 VQETVGLPVVFDCAI-SGSEPISVS-WYKDGKPL----KDSPNVQTSFLDNTATLNIFKT 8119 Query: 93 RAEDSGEYHCVY-HFVSAPKANATI---EVKAAPDITGHKRSENKNEGQDATMYCKSVGY 148 +G+Y C + + + ++A + E K P + G+ A C G Sbjct: 8120 DRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGT 8179 Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 208 W K + + G++ I EN L ++ + D G+Y C A N +G Sbjct: 8180 QPIKVSWAKDSRE-----IRSGGKYQISYLENSAHLTVLKVD-KGDSGQYTCYAVNEVGK 8233 Query: 209 ASVVTVLRVRSHLAP 223 S L ++ L P Sbjct: 8234 DSCTAQLNIKERLIP 8248 Score = 37.7 bits (86), Expect = 0.011 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193 +EG+ T+ C G P P+ W G GRF I N ++ T L I+++Q + Sbjct: 33341 DEGKVLTVACAFTGEPTPEVTW---SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ-KQ 33396 Query: 194 DPGEYECNATNAIGSASVVTVLRVRS 219 D G Y + N GS S + +RS Sbjct: 33397 DGGLYTLSLGNEFGSDSATVNIHIRS 33422 Score = 37.0 bits (84), Expect = 0.019 Identities = 43/158 (27%), Positives = 64/158 (40%), Gaps = 13/158 (8%) Query: 68 WTKNGVEL--SATR---KNASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAA 121 W K+ EL A R K+ ++ + +A DSG Y C + + V + AT+ VK Sbjct: 4801 WFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEP 4860 Query: 122 PD-ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 P I GQ T C+ G P W +G + + G FI + Sbjct: 4861 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYL--DGNEITAIQKHGISFI---DG 4915 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 I ++ E+ G Y C A N G+AS L+V+ Sbjct: 4916 LATFQISGARV-ENSGTYVCEARNDAGTASCSIELKVK 4952 Score = 37.0 bits (84), Expect = 0.019 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 6/99 (6%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP I + G+ A + C+ VG P PD W + + R + ++ + Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKEL------IQSRKYKMSSDG 30585 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 T V + ED G Y C ATN +G + L +++ Sbjct: 30586 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 30624 Score = 36.6 bits (83), Expect = 0.025 Identities = 51/209 (24%), Positives = 78/209 (37%), Gaps = 23/209 (11%) Query: 18 SGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQC-NLTSSSHTLTYSYWTKNGVELS 76 SG+L+ Q P VT VLP + C T T W K EL Sbjct: 4197 SGALI-----VQEPPSFVTKPG----SKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELV 4247 Query: 77 A-----TRKNASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKA-APDITGHKR 129 + K A + + DSG Y C V + + +A + VK A + + Sbjct: 4248 SGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEP 4307 Query: 130 SENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNL 189 S+ +G + CK G P W + + S + + E+ L + ++ Sbjct: 4308 SQLLKKGDATQLACKVTGTPPIKITWFANDRE-----IKESSKHRMSFVESTAVLRLTDV 4362 Query: 190 QITEDPGEYECNATNAIGSASVVTVLRVR 218 I ED GEY C A N GS +++ V+ Sbjct: 4363 GI-EDSGEYMCEAQNEAGSDHCSSIVIVK 4390 Score = 35.8 bits (81), Expect = 0.043 Identities = 39/143 (27%), Positives = 57/143 (39%), Gaps = 18/143 (12%) Query: 116 IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFI 175 +E+KAAP I G A C+ P+ + W K + S + I Sbjct: 3450 MEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE-----IYESDKCSI 3504 Query: 176 INKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP--------LWPF 227 + + + L I+ Q+ D GEY C A+N GS S L V P L F Sbjct: 3505 RSSKYISSLEILRTQVV-DCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTF 3563 Query: 228 LGILAEIIILV----VIIVVYEK 246 +G A+ I V VI +++K Sbjct: 3564 VGKAAKFICTVTGTPVIETIWQK 3586 Score = 35.4 bits (80), Expect = 0.057 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%) Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169 PK++ I+ AP R+ N +AT+ CK G+P P W ++ + D + Sbjct: 30919 PKSDVPIQ---APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKY 30975 Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 + F K Y +L I ++ +D Y+ ATN GS S L V Sbjct: 30976 RIQEF---KGGYHQLIIASV-TDDDATVYQVRATNQGGSVSGTASLEV 31019 Score = 34.7 bits (78), Expect = 0.097 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 5/85 (5%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 EGQ A K VG P P+ W + D + ++ KE+ T+ I+ D Sbjct: 1470 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK-----VVIKEDGTQSLIIVPATPSD 1524 Query: 195 PGEYECNATNAIGSASVVTVLRVRS 219 GE+ A N G +S+ +L V + Sbjct: 1525 SGEWTVVAQNRAGRSSISVILTVEA 1549 Score = 34.7 bits (78), Expect = 0.097 Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 33/155 (21%) Query: 68 WTKNGVELSATRKNASNMEYRIN-------KPRAEDSGEYHCVYHFVSAPK-ANATIEVK 119 W +N + + K+ E +I+ KPR D GEY F++ K A A +E+ Sbjct: 12944 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR--DQGEYR----FIAKDKEARAKLELA 12997 Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTS--------- 170 AAP I + + G+ TM YP + W K+ + ++T+ Sbjct: 12998 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRIL 13057 Query: 171 -------GRFFII--NKENYTELNIVNLQITEDPG 196 GR+ I+ NK E +NL++ + PG Sbjct: 13058 EAKKGDKGRYKIVLQNKHGKAE-GFINLKVIDVPG 13091 Score = 33.5 bits (75), Expect = 0.22 Identities = 43/189 (22%), Positives = 73/189 (38%), Gaps = 21/189 (11%) Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90 EP + +I+ + P TL+ + + W K+G L A++K + + + Sbjct: 4015 EPAKIIERAELIQVTAGDPATLEYTVAGTPELKPK--WYKDGRPLVASKKYRISFKNNVA 4072 Query: 91 KPR-----AEDSGEYHC-VYHFVSAPKANATIEV---KAAPDITGHKRSENKNEGQDATM 141 + + DSG+Y + + V + T V AP T R+ + + Sbjct: 4073 QLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRL 4132 Query: 142 YCKSVGY--PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYE 199 CK G W KE + S R+ I E L I+ + + D G + Sbjct: 4133 DCKIAGSLPMRVSWFKDGKE-------IAASDRYRIAFVEGTASLEIIRVDMN-DAGNFT 4184 Query: 200 CNATNAIGS 208 C ATN++GS Sbjct: 4185 CRATNSVGS 4193 Score = 32.3 bits (72), Expect = 0.48 Identities = 30/145 (20%), Positives = 57/145 (39%), Gaps = 10/145 (6%) Query: 74 ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENK 133 +++ TR++ S+ E+ + + E + + K T+ + I RS Sbjct: 32517 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR----ILTKPRSMTV 32572 Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193 EG+ A C + G P P W +K +++TS R + + + I ++Q Sbjct: 32573 YEGESARFSCDTDGEPVPTVTWLRKG-----QVLSTSARHQVTTTKYKSTFEISSVQ-AS 32626 Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218 D G Y N+ G L ++ Sbjct: 32627 DEGNYSVVVENSEGKQEAEFTLTIQ 32651 Score = 32.0 bits (71), Expect = 0.63 Identities = 31/128 (24%), Positives = 46/128 (35%), Gaps = 7/128 (5%) Query: 97 SGEYHCVYHFVSA-PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIW 155 SG Y C S + A + V+ I +S + E T+ C G P W Sbjct: 5115 SGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKW 5174 Query: 156 RKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 215 K + R+F ++ EN + + +D G+Y N GS+S L Sbjct: 5175 LKDGKQI------VPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYL 5228 Query: 216 RVRSHLAP 223 RV P Sbjct: 5229 RVLDQNIP 5236 Score = 31.6 bits (70), Expect = 0.82 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%) Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178 K PDI + EG+ A C+ GYP P W NG ++ S R F + Sbjct: 1838 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL--NG---QLIRKSKR-FRVRY 1891 Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIG 207 + L+IV+ + + D GE + A N G Sbjct: 1892 DGIHYLDIVDCK-SYDTGEVKVTAENPEG 1919 Score = 31.6 bits (70), Expect = 0.82 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 7/84 (8%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE-NYTELNIVNLQITE 193 EGQ + G P P W K +G P+ + II++ +Y L+I + + E Sbjct: 31808 EGQSVCFEIRVSGIPPPTLKWEK--DGQPLSL---GPNIEIIHEGLDYYALHIRDT-LPE 31861 Query: 194 DPGEYECNATNAIGSASVVTVLRV 217 D G Y ATN GS S L+V Sbjct: 31862 DTGYYRVTATNTAGSTSCQAHLQV 31885 Score = 31.2 bits (69), Expect = 1.1 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%) Query: 136 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-ED 194 G+D + G P P WRK E + D R+ I N ++ + L I Q+T D Sbjct: 27286 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-----ARYSIENTDSSSLLTIP--QVTRND 27338 Query: 195 PGEYECNATNAIGSASVVTV 214 G+Y N +G TV Sbjct: 27339 TGKYILTIENGVGEPKSSTV 27358 Score = 30.8 bits (68), Expect = 1.4 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 5/99 (5%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP I +S+ +G DA + VG P P+ W K NG+ ++ + ++ ++N Sbjct: 2077 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK--NGVKIE--RSDRIYWYWPEDN 2132 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 EL ++ ED A N G S L V++ Sbjct: 2133 VCEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2170 Score = 30.8 bits (68), Expect = 1.4 Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 16/162 (9%) Query: 60 SHTLTYSYWTKNGVELSATRKNASNMEYRINK-----PRAEDSGEYHCVYHFVSAPKANA 114 SH S W KNGVE+ + K ++ ++++ EDS EY V + +A Sbjct: 2906 SHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV---CGNDQVSA 2962 Query: 115 TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFF 174 T+ V P + + E +D + +V Y + W K NG+ + ++ + Sbjct: 2963 TLTV--TPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLK--NGVE---IKSTDKCQ 3015 Query: 175 IINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 216 + K+ LNI N+ D +Y A A +A++ R Sbjct: 3016 MRTKKLTHSLNIRNVHF-GDAADYTFVAGKATSTATLYVEAR 3056 Score = 30.8 bits (68), Expect = 1.4 Identities = 42/179 (23%), Positives = 66/179 (36%), Gaps = 38/179 (21%) Query: 51 TLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYH--------- 101 TL C +T H W + G E+ A ++YRI E G YH Sbjct: 30946 TLVCKVTG--HPKPIVKWYRQGKEIIA-----DGLKYRIQ----EFKGGYHQLIIASVTD 30994 Query: 102 ---CVYHFVSAPKAN-----ATIEVKAAPDITGHKRSENKN-----EGQDATMYCKSVGY 148 VY + + A++EV+ I K E G+ ++ G Sbjct: 30995 DDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGK 31054 Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207 P P W+K + D+++ +G + +I ++T L N +D G Y A N G Sbjct: 31055 PDPVITWQKGQ-----DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 31108 Score = 30.8 bits (68), Expect = 1.4 Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 8/110 (7%) Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169 PKA I K P I + + A K+ G P P IW K + T Sbjct: 32842 PKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAI------T 32893 Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 G + ++++ ++ T D G Y C N+ GS S L +++ Sbjct: 32894 QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 32943 Score = 30.4 bits (67), Expect = 1.8 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 7/62 (11%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G P P +W K+E + D R I N +EL I+ + +D G Y ATN+ Sbjct: 15130 GRPVPTKVWTKEEGELDKD------RVVIDNVGTKSEL-IIKDALRKDHGRYVITATNSC 15182 Query: 207 GS 208 GS Sbjct: 15183 GS 15184 Score = 29.6 bits (65), Expect = 3.1 Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 6/99 (6%) Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 179 A P+ +S +G + + G P P + + +G + S F I++E Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQ----SSLDFQISQE 155 Query: 180 NYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 ++ ED G Y NATN++G A+ L V+ Sbjct: 156 GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 29.3 bits (64), Expect = 4.1 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 EG T +CK GYP P W K +G + F+ + + +V + ED Sbjct: 1304 EGMGVTFHCKMSGYPLPKIAWYK--DGKRIKHGERYQMDFLQDGRASLRIPVV---LPED 1358 Query: 195 PGEYECNATNAIGSA 209 G Y A+N G+A Sbjct: 1359 EGIYTAFASNIKGNA 1373 Score = 29.3 bits (64), Expect = 4.1 Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G P P W + + D + + +N++ + + + D GEY+ +NA Sbjct: 17536 GVPVPTAKWTTDGSEIKTD------EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 17589 Query: 207 GSASVVTVLRV 217 GS +V L V Sbjct: 17590 GSKTVAVHLTV 17600 Score = 28.9 bits (63), Expect = 5.3 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 6/82 (7%) Query: 136 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDP 195 G AT+ G P W K +G P+ S ++ I K N +L + ++ D Sbjct: 4031 GDPATLEYTVAGTPELKPKWYK--DGRPLV---ASKKYRISFKNNVAQLKFYSAEL-HDS 4084 Query: 196 GEYECNATNAIGSASVVTVLRV 217 G+Y +N +GS+S T V Sbjct: 4085 GQYTFEISNEVGSSSCETTFTV 4106 Score = 28.9 bits (63), Expect = 5.3 Identities = 36/161 (22%), Positives = 60/161 (37%), Gaps = 17/161 (10%) Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATI---EV 118 W KN +E+ T + + ++ K D+G Y C V + + ++I E Sbjct: 8283 WYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEP 8342 Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM-PMDIVNTSGRFFIIN 177 K P H +EG+ + C G W K + P D + F + Sbjct: 8343 KKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCS----FSFAS 8398 Query: 178 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 EL V D G+Y C A+N GS + + + ++ Sbjct: 8399 GTAVLELRDV---AKADSGDYVCKASNVAGSDTTKSKVTIK 8436 Score = 28.9 bits (63), Expect = 5.3 Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G PHP W+K E+ ++V +S ++K + + + I+ +D G Y A N+ Sbjct: 18924 GKPHPTCKWKKGED----EVVTSS--HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSS 18977 Query: 207 GS 208 G+ Sbjct: 18978 GT 18979 Score = 28.5 bits (62), Expect = 6.9 Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 4/103 (3%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP T +S EG AT G+P P+ W + +G + G I + Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFR--DGQVISTSTLPG-VQISFSDG 61 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223 +L I + + G Y ATN G A+ L V++ AP Sbjct: 62 RAKLTIPAVT-KANSGRYSLKATNGSGQATSTAELLVKAETAP 103 Score = 28.1 bits (61), Expect = 9.0 Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 6/71 (8%) Query: 96 DSGEYHCVYH------FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 149 DSGE+ V +S +E + P ++ N EG M ++ G P Sbjct: 1524 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1583 Query: 150 HPDWIWRKKEN 160 +PD +W K + Sbjct: 1584 NPDIVWLKNSD 1594 Score = 28.1 bits (61), Expect = 9.0 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 147 GYPHPDWIWRKKENGM--PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 G P P W K E + P D + + + + E TEL+I + ED G Y A+N Sbjct: 15424 GLPMPKIEWSKNETVIEKPTDALQIT-KEEVSRSEAKTELSIPKA-VREDKGTYTVTASN 15481 Query: 205 AIGS 208 +GS Sbjct: 15482 RLGS 15485 >gi|109150416 peroxidasin [Homo sapiens] Length = 1479 Score = 67.4 bits (163), Expect = 1e-11 Identities = 59/207 (28%), Positives = 88/207 (42%), Gaps = 25/207 (12%) Query: 27 AAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSY-----------WTKNGVEL 75 A N + + +I++ P VT Q + T+ + WTK G +L Sbjct: 414 ATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQL 473 Query: 76 SATRKNA--SNMEYRINKPRAEDSGEYHC-VYHFVSAPK--ANATIEVKAAPDITGHKRS 130 S R++ S+ RI+ D G+Y C + + + K A+ T++ + P Sbjct: 474 SVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSD 533 Query: 131 ENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQ 190 G + + C S G P P W K +G+ V SG+F I + E + +N V Sbjct: 534 TTVEVGANVQLPCSSQGEPEPAITWNK--DGVQ---VTESGKFHI-SPEGFLTINDVG-- 585 Query: 191 ITEDPGEYECNATNAIGSASVVTVLRV 217 D G YEC A N IGSASV VL V Sbjct: 586 -PADAGRYECVARNTIGSASVSMVLSV 611 Score = 56.6 bits (135), Expect = 2e-08 Identities = 41/131 (31%), Positives = 60/131 (45%), Gaps = 10/131 (7%) Query: 96 DSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154 DSGEY C + + + A A I V+A P T + EGQ C++ G P P Sbjct: 406 DSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIA 465 Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTV 214 W K + + +D R ++ ++ V L D G+YEC A N IGS VV Sbjct: 466 WTKGGSQLSVD------RRHLVLSSGTLRISGVALH---DQGQYECQAVNIIGSQKVVAH 516 Query: 215 LRVRSHLAPLW 225 L V+ + P++ Sbjct: 517 LTVQPRVTPVF 527 Score = 44.7 bits (104), Expect = 9e-05 Identities = 39/165 (23%), Positives = 63/165 (38%), Gaps = 25/165 (15%) Query: 68 WTKNGVELSATRKNASNM----EYRINKPRAEDSGEYHCVYHFVSAPKANATIEVK---- 119 W +N ELS + N+ I + D G Y C+ V+ + ++ Sbjct: 279 WLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGS 338 Query: 120 -AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIW-RKKENGMPMD---IVNTSGRFF 174 A P ++ G+ T+ C + G+P P W R +P+D + SG + Sbjct: 339 PARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLY 398 Query: 175 IINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 I N + D GEY C+ATN I S + V++ Sbjct: 399 IQN------------VVQGDSGEYACSATNNIDSVHATAFIIVQA 431 Score = 38.5 bits (88), Expect = 0.007 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 7/93 (7%) Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181 P IT + + G C++ G P P+ IW + N + M T R +++ Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSM---KTDSRLNLLDDGT- 301 Query: 182 TELNIVNLQITEDPGEYECNATNAIGSASVVTV 214 L I N Q T D G Y+C A N G V Sbjct: 302 --LMIQNTQET-DQGIYQCMAKNVAGEVKTQEV 331 >gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapiens] Length = 848 Score = 59.7 bits (143), Expect = 3e-09 Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 30/237 (12%) Query: 10 LALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVL---PVTLQC--NLTSSSHTLT 64 L+ + L + G G + E RI+ E+ +D V+ P T+Q N+ +++ L Sbjct: 169 LSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLG 228 Query: 65 YSY---------------WTKNGVELSATRKNAS------NMEYRINKPRAEDSGEYHCV 103 S WTK+G ++ + + + I K D EY C+ Sbjct: 229 QSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICI 288 Query: 104 YHFVSAPKANATIEVK--AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161 A + +ATI +K A P IT + + T+ C++ G P P WR Sbjct: 289 AEN-KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRN 347 Query: 162 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 + + G + + + L + ++Q T D GEY C A+N IG S L V+ Sbjct: 348 ISSEEKTLDGHMVVRSHARVSSLTLKSIQYT-DAGEYICTASNTIGQDSQSMYLEVQ 403 Score = 43.9 bits (102), Expect = 2e-04 Identities = 35/156 (22%), Positives = 61/156 (39%), Gaps = 16/156 (10%) Query: 54 CNLTSSSHTLTYSYWTKNGVELSATRKNAS-------NMEYRINKPRAEDSGEYHCVYHF 106 C + + S+++ NG +L+ ++ S + I +D+G Y CV Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTG 100 Query: 107 VSAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164 ++ AT+ VK + + EG+DA + C V P IW+ K Sbjct: 101 EDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGR---- 156 Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200 D++ FI+ NY ++ + D G Y C Sbjct: 157 DVILKKDVRFIVLSNNYLQIRGIK---KTDEGTYRC 189 Score = 37.7 bits (86), Expect = 0.011 Identities = 33/131 (25%), Positives = 50/131 (38%), Gaps = 26/131 (19%) Query: 96 DSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154 D+GEY C + + + +EV+ AP + G EG + C+ YP Sbjct: 379 DAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSATIS 437 Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVN------LQITEDP----GEYECNATN 204 W + +P NY+ + I N L++T D G Y C A N Sbjct: 438 WFRDGQLLP--------------SSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVN 483 Query: 205 AIGSASVVTVL 215 IG S+ +L Sbjct: 484 RIGQESLEFIL 494 >gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sapiens] Length = 761 Score = 59.7 bits (143), Expect = 3e-09 Identities = 58/237 (24%), Positives = 96/237 (40%), Gaps = 30/237 (12%) Query: 10 LALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVL---PVTLQC--NLTSSSHTLT 64 L+ + L + G G + E RI+ E+ +D V+ P T+Q N+ +++ L Sbjct: 169 LSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLG 228 Query: 65 YSY---------------WTKNGVELSATRKNAS------NMEYRINKPRAEDSGEYHCV 103 S WTK+G ++ + + + I K D EY C+ Sbjct: 229 QSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICI 288 Query: 104 YHFVSAPKANATIEVK--AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161 A + +ATI +K A P IT + + T+ C++ G P P WR Sbjct: 289 AEN-KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRN 347 Query: 162 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 + + G + + + L + ++Q T D GEY C A+N IG S L V+ Sbjct: 348 ISSEEKTLDGHMVVRSHARVSSLTLKSIQYT-DAGEYICTASNTIGQDSQSMYLEVQ 403 Score = 43.9 bits (102), Expect = 2e-04 Identities = 35/156 (22%), Positives = 61/156 (39%), Gaps = 16/156 (10%) Query: 54 CNLTSSSHTLTYSYWTKNGVELSATRKNAS-------NMEYRINKPRAEDSGEYHCVYHF 106 C + + S+++ NG +L+ ++ S + I +D+G Y CV Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTG 100 Query: 107 VSAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164 ++ AT+ VK + + EG+DA + C V P IW+ K Sbjct: 101 EDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGR---- 156 Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200 D++ FI+ NY ++ + D G Y C Sbjct: 157 DVILKKDVRFIVLSNNYLQIRGIK---KTDEGTYRC 189 Score = 37.7 bits (86), Expect = 0.011 Identities = 33/131 (25%), Positives = 50/131 (38%), Gaps = 26/131 (19%) Query: 96 DSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154 D+GEY C + + + +EV+ AP + G EG + C+ YP Sbjct: 379 DAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSATIS 437 Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVN------LQITEDP----GEYECNATN 204 W + +P NY+ + I N L++T D G Y C A N Sbjct: 438 WFRDGQLLP--------------SSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVN 483 Query: 205 AIGSASVVTVL 215 IG S+ +L Sbjct: 484 RIGQESLEFIL 494 >gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] Length = 1215 Score = 56.6 bits (135), Expect = 2e-08 Identities = 45/182 (24%), Positives = 78/182 (42%), Gaps = 12/182 (6%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINK 91 P + S +R PV+L C + + L +W K+G L +++ + ++ Sbjct: 767 PPQIASSAPTVRVLEGQPVSLPC-IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHL 825 Query: 92 PRA--EDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGY 148 RA E +G Y CV + + + + V+ P I NEG A++ C + G Sbjct: 826 DRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGV 885 Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 208 P P W K+ N + + G + ++KE ++ +D G Y C ATN +G Sbjct: 886 PAPTITWTKETNAL-----TSRGPHYNVSKEGTL---LIAQPSAQDAGAYVCTATNTVGF 937 Query: 209 AS 210 +S Sbjct: 938 SS 939 Score = 55.5 bits (132), Expect = 5e-08 Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 3/157 (1%) Query: 68 WTKNGVELSATRKNASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITG 126 W + G+E+ + +S+ + RI + D+G Y C + + A + V AP +T Sbjct: 614 WYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTE 673 Query: 127 HKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNI 186 R G+ A + C++ G P P WR+ + G P+ + +GR + + L Sbjct: 674 LPRDVTVELGRSALLACRATGRPPPTVTWRRGD-GQPLGLRLGAGRGSRSRQPDSGVLFF 732 Query: 187 VNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223 ++ ED Y C A N G L V H P Sbjct: 733 ESV-APEDQAPYVCEARNVFGKVQAEARLIVTGHAPP 768 Score = 53.9 bits (128), Expect = 2e-07 Identities = 45/185 (24%), Positives = 79/185 (42%), Gaps = 25/185 (13%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRKNAS---NMEY 87 P++V + V + SP L C L + + LT W ++ L A+ + ++ Sbjct: 401 PQLVPAPNVTV--SPGETAVLSCRVLGEAPYNLT---WVRDWRVLPASTGRVAQLADLSL 455 Query: 88 RINKPRAEDSGEYHCVYHFVSA-PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146 I+ D G Y CV + +A+ + V+ AP ++ H S++ ++G + + C + Sbjct: 456 EISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSAS 515 Query: 147 GYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203 GYP P W ++ + D V+ G I+ ED G Y C AT Sbjct: 516 GYPTPHISWSRESQALQEDSRIHVDAQGTL------------IIQGVAPEDAGNYSCQAT 563 Query: 204 NAIGS 208 N +G+ Sbjct: 564 NEVGT 568 Score = 45.8 bits (107), Expect = 4e-05 Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 23/183 (12%) Query: 48 LPVTLQCNLTS-SSHTLTYSYWTK--NGVELSATRKNASNM-EYRINKPRAEDSGEYHCV 103 +P +L C + + T+T WTK N + N S I +P A+D+G Y C Sbjct: 874 VPASLPCVASGVPAPTIT---WTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCT 930 Query: 104 YHFV---SAPKANATIEVKAAPDITGHKRSE-----NKNEGQDATMYCKSVGYPHPDWIW 155 S+ + ++ K + G + + G++ T+ C++ G P P W Sbjct: 931 ATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEAKGSPPPLVTW 990 Query: 156 RKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 215 K +P + R+ ++ + L + +Q+ D G YEC A+N GSAS VL Sbjct: 991 TKDSRPVPP----ITNRYGLLPSGS---LRLAQVQVG-DSGHYECTASNPAGSASHRYVL 1042 Query: 216 RVR 218 V+ Sbjct: 1043 GVQ 1045 Score = 38.9 bits (89), Expect = 0.005 Identities = 32/127 (25%), Positives = 51/127 (40%), Gaps = 18/127 (14%) Query: 95 EDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 153 ED+G Y C + V + T+ P ++ G++A + C++ G P P Sbjct: 553 EDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRV 612 Query: 154 IWRKKENGMPMDIV---NTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210 IW + G+ M + ++SG+ I + D G Y C A N +G AS Sbjct: 613 IWYR--GGLEMILAPEGSSSGKLRIPAAQE------------RDAGTYTCRAVNELGDAS 658 Query: 211 VVTVLRV 217 L V Sbjct: 659 AEIQLAV 665 Score = 29.3 bits (64), Expect = 4.1 Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 17/144 (11%) Query: 80 KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQD 138 + + N + I + + G Y C +A A I V P + + G+ Sbjct: 357 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGET 416 Query: 139 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----ED 194 A + C+ +G + W + +P ++GR +L ++L+I+ D Sbjct: 417 AVLSCRVLGEAPYNLTWVRDWRVLPA----STGRV--------AQLADLSLEISGIIPTD 464 Query: 195 PGEYECNATNAIGSASVVTVLRVR 218 G Y+C A+NA G L VR Sbjct: 465 GGRYQCVASNANGVTRASVWLLVR 488 >gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] Length = 5065 Score = 56.6 bits (135), Expect = 2e-08 Identities = 45/182 (24%), Positives = 78/182 (42%), Gaps = 12/182 (6%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINK 91 P + S +R PV+L C + + L +W K+G L +++ + ++ Sbjct: 884 PPQIASSAPTVRVLEGQPVSLPC-IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHL 942 Query: 92 PRA--EDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGY 148 RA E +G Y CV + + + + V+ P I NEG A++ C + G Sbjct: 943 DRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGV 1002 Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 208 P P W K+ N + + G + ++KE ++ +D G Y C ATN +G Sbjct: 1003 PAPTITWTKETNAL-----TSRGPHYNVSKEGTL---LIAQPSAQDAGAYVCTATNTVGF 1054 Query: 209 AS 210 +S Sbjct: 1055 SS 1056 Score = 55.5 bits (132), Expect = 5e-08 Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 3/157 (1%) Query: 68 WTKNGVELSATRKNASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITG 126 W + G+E+ + +S+ + RI + D+G Y C + + A + V AP +T Sbjct: 731 WYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTE 790 Query: 127 HKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNI 186 R G+ A + C++ G P P WR+ + G P+ + +GR + + L Sbjct: 791 LPRDVTVELGRSALLACRATGRPPPTVTWRRGD-GQPLGLRLGAGRGSRSRQPDSGVLFF 849 Query: 187 VNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223 ++ ED Y C A N G L V H P Sbjct: 850 ESV-APEDQAPYVCEARNVFGKVQAEARLIVTGHAPP 885 Score = 53.9 bits (128), Expect = 2e-07 Identities = 45/185 (24%), Positives = 79/185 (42%), Gaps = 25/185 (13%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRKNAS---NMEY 87 P++V + V + SP L C L + + LT W ++ L A+ + ++ Sbjct: 518 PQLVPAPNVTV--SPGETAVLSCRVLGEAPYNLT---WVRDWRVLPASTGRVAQLADLSL 572 Query: 88 RINKPRAEDSGEYHCVYHFVSA-PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146 I+ D G Y CV + +A+ + V+ AP ++ H S++ ++G + + C + Sbjct: 573 EISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSAS 632 Query: 147 GYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203 GYP P W ++ + D V+ G I+ ED G Y C AT Sbjct: 633 GYPTPHISWSRESQALQEDSRIHVDAQGTL------------IIQGVAPEDAGNYSCQAT 680 Query: 204 NAIGS 208 N +G+ Sbjct: 681 NEVGT 685 Score = 52.4 bits (124), Expect = 4e-07 Identities = 46/160 (28%), Positives = 70/160 (43%), Gaps = 17/160 (10%) Query: 68 WTKNGVELSA--TRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDI 124 W K G+ ++ + + + RI ED+G Y C+ + + + V+ P I Sbjct: 3981 WQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVI 4040 Query: 125 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 184 + EG A + CK+ G P P+ W K +G P + G+F I + EL Sbjct: 4041 ENGLPDLSTTEGSHAFLPCKARGSPEPNITWDK--DGQP--VSGAEGKFTI---QPSGEL 4093 Query: 185 NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPL 224 + NL+ +D G Y C A NA+G A R R HL L Sbjct: 4094 LVKNLE-GQDAGTYTCTAENAVGRA------RRRVHLTIL 4126 Score = 50.1 bits (118), Expect = 2e-06 Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 12/162 (7%) Query: 67 YWTKNGVEL--SATRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPD 123 +W K+G+ L S R N I++ +D+G Y C+ + + K + +++AP Sbjct: 4251 HWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPV 4310 Query: 124 ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTE 183 + G D + C++ G P P W + G P+ S R + + Sbjct: 4311 FQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQA--GQPL---RASRRLRTLPDGSLWL 4365 Query: 184 LNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLW 225 N+ T D G Y+C A N +GSA+ L VR W Sbjct: 4366 ENVE----TGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSW 4403 Score = 44.7 bits (104), Expect = 9e-05 Identities = 48/194 (24%), Positives = 74/194 (38%), Gaps = 32/194 (16%) Query: 25 PGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASN 84 P Q PR++ +V++ ++ L N + + W+K+GV L S Sbjct: 1119 PPQVQPGPRVL---KVLVGEA------LDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSV 1169 Query: 85 MEYRINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAAPDITGHKRSE--NKNEGQDATM 141 I R D+G Y C + A + V P + S + G++A++ Sbjct: 1170 HFAAI---RTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASL 1226 Query: 142 YCKSVGYPHPDWIWRKKEN-----GMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPG 196 C + G P P WRK + G P V G F+ + D G Sbjct: 1227 PCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVS------------PADSG 1274 Query: 197 EYECNATNAIGSAS 210 +YEC ATN +GS S Sbjct: 1275 DYECQATNEVGSTS 1288 Score = 44.3 bits (103), Expect = 1e-04 Identities = 60/220 (27%), Positives = 87/220 (39%), Gaps = 25/220 (11%) Query: 17 VSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVL---PVTLQCNLTSS-SHTLTYSYWTKNG 72 V+GS G N P +T + PVL PV L CN T + S TL W K+G Sbjct: 1961 VAGSTELRYGLRVNVPPRITLPPSL--PGPVLVNTPVRLTCNATGAPSPTLM---WLKDG 2015 Query: 73 VELSATRKNASNM-----EYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITG 126 +S + + RA DSG Y CV V + + ++V P I G Sbjct: 2016 NPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILG 2075 Query: 127 HKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNI 186 + + + + + C+S P P W K +G P++ G +K L Sbjct: 2076 EELNVSVVANESVALECQSHAMPPPVLSWWK--DGRPLE--PRPGVHLSADK----ALLQ 2127 Query: 187 VNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWP 226 V+ D G Y C A N G + L V +AP++P Sbjct: 2128 VDRADVWDAGHYTCEALNQAGHSEKHYNLNV--WVAPVFP 2165 Score = 44.3 bits (103), Expect = 1e-04 Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 9/123 (7%) Query: 96 DSGEYHCVYHFVSAPKANA-TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154 DSG+Y C + + A +E+ P I + N + Q A + C++ G P P Sbjct: 3646 DSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVS 3705 Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTV 214 WRK + +P+D S RF I+ + + + + +D G Y C A+N+ GS Sbjct: 3706 WRK--DRVPLD--PRSPRFEILPEGSLR----IQPVLAQDAGHYLCLASNSAGSDRQGRD 3757 Query: 215 LRV 217 LRV Sbjct: 3758 LRV 3760 Score = 42.0 bits (97), Expect = 6e-04 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 11/133 (8%) Query: 88 RINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAAPDITGHKRSENKNEGQD--ATMYCK 144 RI D G Y CV + +A + + V A P I G + +D + C+ Sbjct: 1466 RITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCE 1525 Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 + G P P+ W K +P TS + ++ +L + Q + D G Y C A+N Sbjct: 1526 ARGVPTPNITWFKDGALLP-----TSTK--VVYTRGGRQLQLGRAQ-SSDAGVYTCKASN 1577 Query: 205 AIGSASVVTVLRV 217 A+G+A T L V Sbjct: 1578 AVGAAEKATRLDV 1590 Score = 42.0 bits (97), Expect = 6e-04 Identities = 41/167 (24%), Positives = 66/167 (39%), Gaps = 19/167 (11%) Query: 52 LQCNLTSSSHTLTYSYWTKNGVELS---ATRKNASNMEYRINKPRAEDSGEYHCVY-HFV 107 L CN+T H W K+G L+ A + + ++ + +G Y C+ + V Sbjct: 2465 LMCNVTG--HPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAV 2522 Query: 108 SAPKANATIEVKAAPDITGHKRSENKNE-----GQDATMYCKSVGYPHPDWIWRKKENGM 162 + + V AP I G E ++ C+++ +P P+ W K +G Sbjct: 2523 GEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK--DGA 2580 Query: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 209 P + I L I+N Q ED G+Y C TN +G A Sbjct: 2581 PFEASRN-----IQLLPGTHGLQILNAQ-KEDAGQYTCVVTNELGEA 2621 Score = 41.6 bits (96), Expect = 8e-04 Identities = 46/184 (25%), Positives = 74/184 (40%), Gaps = 22/184 (11%) Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGV---ELSATRKNASNMEYRINKPRAEDSGEYHCVYH 105 PV L+C + H W G+ E + +R R+ P SG Y CV Sbjct: 1613 PVALEC--VARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCV-- 1668 Query: 106 FVSAPKANA----TIEVKAAPDITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKE 159 S+P A ++EV+ P + + GQ + C++ G P P W + Sbjct: 1669 -ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL--Q 1725 Query: 160 NGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 NG P + +G + T L+I ++++ + G + C ATN G+A + V Sbjct: 1726 NGRPAE--ELAG---VQVASQGTTLHIDHVEL-DHSGLFACQATNEAGTAGAEVEVSVHG 1779 Query: 220 HLAP 223 AP Sbjct: 1780 EWAP 1783 Score = 40.4 bits (93), Expect = 0.002 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 11/123 (8%) Query: 88 RINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSE--NKNEGQDATMYCK 144 ++ + + +DSG Y C+ + + N ++EV P I E +GQ A + C Sbjct: 2409 KMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCN 2468 Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 G+P P W K +G P+ G I+ + L ++ ++ G Y C A N Sbjct: 2469 VTGHPQPKLTWFK--DGRPL----ARGDAHHISPDGVL-LQVLQANLS-SAGHYSCIAAN 2520 Query: 205 AIG 207 A+G Sbjct: 2521 AVG 2523 Score = 40.0 bits (92), Expect = 0.002 Identities = 45/166 (27%), Positives = 75/166 (45%), Gaps = 16/166 (9%) Query: 49 PVTLQCNLTS-SSHTLTYSYWTKNG--VELSATRKNASNM-EYRINKPRAEDSGEYHCVY 104 P+ L C+++ + T+T W K+ VE SA S ++++ + +G Y CV Sbjct: 3141 PLVLTCDVSGVPAPTVT---WLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 3197 Query: 105 HFVSAP-KANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161 A + + + V AP I +G R + EGQ+ + C++ G P PD W K + Sbjct: 3198 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSP 3257 Query: 162 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207 + D + RF++ + L + L+ D G Y C A N G Sbjct: 3258 LGQD-MGPHLRFYL----DGGSLVLKGLR-ASDAGAYTCVAHNPAG 3297 Score = 39.7 bits (91), Expect = 0.003 Identities = 45/184 (24%), Positives = 73/184 (39%), Gaps = 23/184 (12%) Query: 45 SPVLPVTLQCNLTSSSH-TLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCV 103 +P P+ L C+ + +T W K+G L+ N+ R D+G Y C+ Sbjct: 3508 TPGAPMELLCDAQGTPQPNIT---WHKDGQALTRLENNSRATRVL----RVRDAGLYTCL 3560 Query: 104 YHF-VSAPKANATIEVKAAPDITGHKRSE---NKNEGQDATMYCKSVGYPHPDWIWRKKE 159 A + + + V+A P+I G + GQ + C P P W + Sbjct: 3561 AESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQ-LVLECSVEAEPAPKITWHR-- 3617 Query: 160 NGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 +G+ ++ + + +L ++ T D G+Y C A NA GS SV RV Sbjct: 3618 DGI---VLQEDAHTQFPERGRFLQLQALS---TADSGDYSCTARNAAGSTSV--AFRVEI 3669 Query: 220 HLAP 223 H P Sbjct: 3670 HTVP 3673 Score = 38.9 bits (89), Expect = 0.005 Identities = 32/127 (25%), Positives = 51/127 (40%), Gaps = 18/127 (14%) Query: 95 EDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 153 ED+G Y C + V + T+ P ++ G++A + C++ G P P Sbjct: 670 EDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRV 729 Query: 154 IWRKKENGMPMDIV---NTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210 IW + G+ M + ++SG+ I + D G Y C A N +G AS Sbjct: 730 IWYR--GGLEMILAPEGSSSGKLRIPAAQE------------RDAGTYTCRAVNELGDAS 775 Query: 211 VVTVLRV 217 L V Sbjct: 776 AEIQLAV 782 Score = 38.5 bits (88), Expect = 0.007 Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 16/127 (12%) Query: 96 DSGEYHC-VYHFVSAPKANATIEVKAAPDIT--GHKRSENKNEGQDATMYCKSVGYPHPD 152 DSG+Y C + V + A + V P I G K + + GQ T+ C + G+P P+ Sbjct: 1272 DSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPE 1331 Query: 153 WIWRKKEN--GMPMDIVNTS--------GRFFIINKENYTELNIVNLQITEDPGEYECNA 202 +W K G+P+ G ++++ L+ +Q D G Y C A Sbjct: 1332 IVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQ--SLHFPRIQ-EGDSGLYSCRA 1388 Query: 203 TNAIGSA 209 N G+A Sbjct: 1389 ENQAGTA 1395 Score = 38.5 bits (88), Expect = 0.007 Identities = 36/134 (26%), Positives = 52/134 (38%), Gaps = 15/134 (11%) Query: 88 RINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146 +I K D G Y C + K ++V P+I ++ E T+ C + Sbjct: 1851 QIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLAS 1910 Query: 147 GYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203 G P PD W K + + V+ GR L I Q++ D G Y C A+ Sbjct: 1911 GVPPPDVSWFKGHQPVSSWMGVTVSVDGRV----------LRIEQAQLS-DAGSYRCVAS 1959 Query: 204 NAIGSASVVTVLRV 217 N GS + LRV Sbjct: 1960 NVAGSTELRYGLRV 1973 Score = 35.8 bits (81), Expect = 0.043 Identities = 42/204 (20%), Positives = 75/204 (36%), Gaps = 29/204 (14%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSY--WTKNGVELS---ATRKNASNME 86 P + EE+ + V L+C SH + W K+G L +A Sbjct: 2070 PPSILGEELNVSVVANESVALECQ----SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL 2125 Query: 87 YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDIT-GHKRSENKNEGQDATMYCK 144 ++++ D+G Y C + + + + V AP + EG ++ C+ Sbjct: 2126 LQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCE 2185 Query: 145 SVGYPHPDWIWRKKENGMP-----MDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYE 199 G P P WRK +P + V+ GR + + + G Y Sbjct: 2186 CRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQ-----------EGTYT 2234 Query: 200 CNATNAIGSASVVTVLRVRSHLAP 223 C +N +G++S L++ H+ P Sbjct: 2235 CECSNVVGNSS--QDLQLEVHVPP 2256 Score = 35.4 bits (80), Expect = 0.057 Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 13/131 (9%) Query: 93 RAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRS----ENKNEGQDATMYCKSVG 147 RAE++G Y C + V + + V P I G N ++ C ++G Sbjct: 2812 RAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALG 2871 Query: 148 YPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207 P P W +NG+P + S R ++ +++ + D Y C A N G Sbjct: 2872 NPVPTISWL--QNGLPF---SPSPRLQVLEDGQVLQVSTAEVA---DAASYMCVAENQAG 2923 Query: 208 SASVVTVLRVR 218 SA + LRV+ Sbjct: 2924 SAEKLFTLRVQ 2934 Score = 34.3 bits (77), Expect = 0.13 Identities = 34/134 (25%), Positives = 50/134 (37%), Gaps = 21/134 (15%) Query: 88 RINKPRAEDSGEYHCVYHFVSAPKANAT----IEVKAAPDITGHKRSENKNEGQDATMYC 143 R+ + + DSG Y C S P +A+ + V+ P + R G+ + C Sbjct: 1085 RLAQVQVGDSGHYECT---ASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNC 1141 Query: 144 KSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203 + G P P W K D V GR + + T D G Y C A+ Sbjct: 1142 VAEGNPEPQLSWSK-------DGVVLQGR----GPQGSVHFAAIR---TSDAGRYRCEAS 1187 Query: 204 NAIGSASVVTVLRV 217 N+ G + LRV Sbjct: 1188 NSAGVDAWEVELRV 1201 Score = 34.3 bits (77), Expect = 0.13 Identities = 43/200 (21%), Positives = 77/200 (38%), Gaps = 33/200 (16%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90 P + ++ + + PV L C+ T + T++ W+K G +L A YR++ Sbjct: 3856 PPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS---WSKAGAQLGARGSG-----YRVS 3907 Query: 91 KPRAED--------SGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATM 141 A + +G Y C + + + V+A+P + ++ + Sbjct: 3908 PSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLL 3967 Query: 142 YCKSVGYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEY 198 C++ G P P W+K+ + + V G+ I + ED G Y Sbjct: 3968 PCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHAS------------PEDAGNY 4015 Query: 199 ECNATNAIGSASVVTVLRVR 218 C A N+ GSA T L V+ Sbjct: 4016 LCIAKNSAGSAMGKTRLVVQ 4035 Score = 33.5 bits (75), Expect = 0.22 Identities = 39/185 (21%), Positives = 70/185 (37%), Gaps = 17/185 (9%) Query: 38 EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA---SNMEYRINKPRA 94 EEV + S V+LQC + + + W +NG+ S + + +++ Sbjct: 2853 EEVTVNASST--VSLQC--PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 2908 Query: 95 EDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSE-NKNEGQDATMYCKSVGYPHPD 152 D+ Y CV + + + T+ V+ P I G + ++ C +P+P+ Sbjct: 2909 ADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPE 2968 Query: 153 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 212 W K + + F++ + +L L D G Y C A NA G + Sbjct: 2969 VTWYKDSQALSL-----GEEVFLLPGTHTLQLGRARLS---DSGMYTCEALNAAGRDQKL 3020 Query: 213 TVLRV 217 L V Sbjct: 3021 VQLSV 3025 Score = 32.0 bits (71), Expect = 0.63 Identities = 42/189 (22%), Positives = 73/189 (38%), Gaps = 28/189 (14%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSH-TLTYSYWTKNG----VELSATRKNASNME 86 PR ++ +++D TL+CN T T+T W ++G EL +N Sbjct: 2261 PREPPTQVSVVQDGVA---TLECNATGKPPPTVT---WERDGQPVGAELGLQLQN-QGQS 2313 Query: 87 YRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEG---QDATMY 142 + + +A +G Y CV + + + V P++ G T+ Sbjct: 2314 LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLL 2373 Query: 143 CKSVGYPHPDWIWRKKENGMPM--DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200 C+++G P P W + E + D +G + + K T+ +D G Y C Sbjct: 2374 CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWML--KMTQTQ--------EQDSGLYSC 2423 Query: 201 NATNAIGSA 209 A+N G A Sbjct: 2424 LASNEAGEA 2432 Score = 31.2 bits (69), Expect = 1.1 Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 E A +YC + P PD W +++ + + ++ ++ +V E+ Sbjct: 2764 ENNPAYLYCDTNAIPPPDLTWYREDQPL-----SAGDEVSVLQGGRVLQIPLVR---AEN 2815 Query: 195 PGEYECNATNAIG 207 G Y C A+N +G Sbjct: 2816 AGRYSCKASNEVG 2828 Score = 30.0 bits (66), Expect = 2.4 Identities = 30/125 (24%), Positives = 47/125 (37%), Gaps = 12/125 (9%) Query: 89 INKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENK-NEGQD--ATMYCK 144 + + + G Y C + V + +EV P I G + + + QD AT+ C Sbjct: 2222 LGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECN 2281 Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 + G P P W + +G P+ G + +N + V G Y C A N Sbjct: 2282 ATGKPPPTVTWER--DGQPV------GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN 2333 Query: 205 AIGSA 209 G A Sbjct: 2334 LAGRA 2338 Score = 29.3 bits (64), Expect = 4.1 Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 17/144 (11%) Query: 80 KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQD 138 + + N + I + + G Y C +A A I V P + + G+ Sbjct: 474 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGET 533 Query: 139 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----ED 194 A + C+ +G + W + +P ++GR +L ++L+I+ D Sbjct: 534 AVLSCRVLGEAPYNLTWVRDWRVLPA----STGRV--------AQLADLSLEISGIIPTD 581 Query: 195 PGEYECNATNAIGSASVVTVLRVR 218 G Y+C A+NA G L VR Sbjct: 582 GGRYQCVASNANGVTRASVWLLVR 605 Score = 29.3 bits (64), Expect = 4.1 Identities = 43/205 (20%), Positives = 74/205 (36%), Gaps = 25/205 (12%) Query: 26 GAAQNEPRIVTSEEVIIRDS-PVLPVT------LQCNLTSSSH-TLTYSYWTKNGVELSA 77 G+A + R+V +I + P L T L C S +T W K+G +S Sbjct: 4024 GSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNIT---WDKDGQPVSG 4080 Query: 78 TRKNAS---NMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENK 133 + + E + +D+G Y C + V + + + P T + Sbjct: 4081 AEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSL 4140 Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193 G + C + G P P W + + T G + ++ + L + E Sbjct: 4141 RLGDRLWLRCAARGSPTPRIGWTVNDRPV------TEG---VSEQDGGSTLQRAAVS-RE 4190 Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218 D G Y C A N +G V+ + V+ Sbjct: 4191 DSGTYVCWAENRVGRTQAVSFVHVK 4215 >gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1 [Homo sapiens] Length = 1093 Score = 56.6 bits (135), Expect = 2e-08 Identities = 57/245 (23%), Positives = 105/245 (42%), Gaps = 30/245 (12%) Query: 36 TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNG-VELSATRKNASNME-----YRI 89 T ++ IR + + L+C T H W K+G + A R+ ++ + I Sbjct: 604 TPHDITIRTTTM--ARLECAATG--HPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFI 659 Query: 90 NKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGY 148 + +D+G Y C + + ANAT+ V P + + G+ + CK+ G Sbjct: 660 TDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGN 719 Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 208 P P W K + P+ + + +N +L +V + ED G Y C +N +G+ Sbjct: 720 PPPRITWFKGDR--PLSLTERHH----LTPDN--QLLVVQNVVAEDAGRYTCEMSNTLGT 771 Query: 209 ------ASVVTVLRVRSHLAPLWPF-LGILAEIII--LVVIIVVYEKRKRPDE--VPDDD 257 SV+ R + F + +++ I++ LV + ++Y+ RK+ +E V + D Sbjct: 772 ERAHSQLSVLPAAGCRKDGTTVGIFTIAVVSSIVLTSLVWVCIIYQTRKKSEEYSVTNTD 831 Query: 258 EPAGP 262 E P Sbjct: 832 ETVVP 836 >gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3 isoform 2 [Homo sapiens] Length = 1119 Score = 55.5 bits (132), Expect = 5e-08 Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 23/189 (12%) Query: 54 CNLTSSSHT-LTYSYWTKNGVELSATRKNASN--------MEY----RINKPRAEDSGEY 100 C+ SSS + +T+++ N + A +N ++ MEY R+ + G+Y Sbjct: 520 CSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKY 579 Query: 101 HCVY--HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK 158 CV HF S+ A + V P T G A + C +VG+P P W +K Sbjct: 580 QCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAW-QK 638 Query: 159 ENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS---VVTVL 215 + G R ++ +++ IV+++I ED G Y C A N+ GS S +TVL Sbjct: 639 DGGTDFPAAR-ERRMHVMPEDDV--FFIVDVKI-EDIGVYSCTAQNSAGSISANATLTVL 694 Query: 216 RVRSHLAPL 224 S L PL Sbjct: 695 ETPSFLRPL 703 Score = 46.2 bits (108), Expect = 3e-05 Identities = 52/228 (22%), Positives = 90/228 (39%), Gaps = 37/228 (16%) Query: 52 LQCNLTSSSHTLTYSYWTKNG-VELSATRKNASNME-----YRINKPRAEDSGEYHCV-Y 104 L+C + H W K+G + A R+ ++ + I + ED G Y C Sbjct: 622 LEC--AAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQ 679 Query: 105 HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164 + + ANAT+ V P +G+ A + C + G P P W K ++ Sbjct: 680 NSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDS---- 735 Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS------ASVVTVLRVR 218 +V T FF +L I+ D G+Y C +N +G+ SV+ Sbjct: 736 PLVVTERHFFAAG----NQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCD 791 Query: 219 S--HLAPL-----WPFLGILAEIII-------LVVIIVVYEKRKRPDE 252 S AP W +G++ ++ LV ++++Y R+R ++ Sbjct: 792 SPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNED 839 >gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3 isoform 1 [Homo sapiens] Length = 1059 Score = 55.5 bits (132), Expect = 5e-08 Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 23/189 (12%) Query: 54 CNLTSSSHT-LTYSYWTKNGVELSATRKNASN--------MEY----RINKPRAEDSGEY 100 C+ SSS + +T+++ N + A +N ++ MEY R+ + G+Y Sbjct: 460 CSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKY 519 Query: 101 HCVY--HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK 158 CV HF S+ A + V P T G A + C +VG+P P W +K Sbjct: 520 QCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAW-QK 578 Query: 159 ENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS---VVTVL 215 + G R ++ +++ IV+++I ED G Y C A N+ GS S +TVL Sbjct: 579 DGGTDFPAAR-ERRMHVMPEDDV--FFIVDVKI-EDIGVYSCTAQNSAGSISANATLTVL 634 Query: 216 RVRSHLAPL 224 S L PL Sbjct: 635 ETPSFLRPL 643 Score = 46.2 bits (108), Expect = 3e-05 Identities = 52/228 (22%), Positives = 90/228 (39%), Gaps = 37/228 (16%) Query: 52 LQCNLTSSSHTLTYSYWTKNG-VELSATRKNASNME-----YRINKPRAEDSGEYHCV-Y 104 L+C + H W K+G + A R+ ++ + I + ED G Y C Sbjct: 562 LEC--AAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQ 619 Query: 105 HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164 + + ANAT+ V P +G+ A + C + G P P W K ++ Sbjct: 620 NSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDS---- 675 Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS------ASVVTVLRVR 218 +V T FF +L I+ D G+Y C +N +G+ SV+ Sbjct: 676 PLVVTERHFFAAG----NQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCD 731 Query: 219 S--HLAPL-----WPFLGILAEIII-------LVVIIVVYEKRKRPDE 252 S AP W +G++ ++ LV ++++Y R+R ++ Sbjct: 732 SPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNED 779 >gi|118572606 hemicentin 1 [Homo sapiens] Length = 5635 Score = 55.1 bits (131), Expect = 7e-08 Identities = 48/163 (29%), Positives = 71/163 (43%), Gaps = 12/163 (7%) Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA--SNMEYRINKPRAEDSGEYHCVYHFV 107 +TL C L + + + W KN L S+ I + + +D GEY CV V Sbjct: 907 LTLPCTLLAGN-PIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNV 965 Query: 108 SAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDI 166 + T + V P I ++ + EG T+ CK+ G P P IW KK ++ Sbjct: 966 AGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKG-----EL 1020 Query: 167 VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 209 ++TS F + L +V+ E+ GEY C ATN G A Sbjct: 1021 ISTSSAKFSAGADG--SLYVVS-PGGEESGEYVCTATNTAGYA 1060 Score = 53.9 bits (128), Expect = 2e-07 Identities = 54/205 (26%), Positives = 88/205 (42%), Gaps = 31/205 (15%) Query: 30 NEPRIVT---SEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME 86 +EP ++ SE +I ++P+L L C T + + W K G+ ++ + +N + + Sbjct: 3985 HEPPVIQPQPSELHVILNNPIL---LPCEATGTPSP--FITWQKEGINVNTSGRNHAVLP 4039 Query: 87 ---YRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMY 142 +I++ ED+G Y CV + + V+ P I+ H + + T+ Sbjct: 4040 SGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLS 4099 Query: 143 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----EDPGEY 198 C++ G P PD W K GR I+ L+ +LQI D G Y Sbjct: 4100 CEADGLPPPDITWHK------------DGRA-IVESIRQRVLSSGSLQIAFVQPGDAGHY 4146 Query: 199 ECNATNAIGSASVVTVLRVRSHLAP 223 C A N GS+S T L V H+ P Sbjct: 4147 TCMAANVAGSSSTSTKLTV--HVPP 4169 Score = 52.0 bits (123), Expect = 6e-07 Identities = 49/208 (23%), Positives = 84/208 (40%), Gaps = 31/208 (14%) Query: 24 GPGAAQ-----NEPRIVTSEEVIIRDSPVLPVTLQCNLTSS-SHTLTYSYWTKNGVELS- 76 G G AQ +EP V + +P L C + S+ + LT W +N ++ Sbjct: 506 GTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLT---WQRNDRDVRL 562 Query: 77 ---ATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSEN 132 A + +N+ + + D+GEYHC+ A + + V+ P +T ++++ Sbjct: 563 AEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQS 622 Query: 133 KNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQI- 191 G + ++ C + GYP P W T FI+ Y + L I Sbjct: 623 FTGGSEVSIMCSATGYPKPKIAW-------------TVNDMFIVGSHRYRMTSDGTLFIK 669 Query: 192 ---TEDPGEYECNATNAIGSASVVTVLR 216 +D G Y C A+N+ G+ + LR Sbjct: 670 NAAPKDAGIYGCLASNSAGTDKQNSTLR 697 Score = 49.7 bits (117), Expect = 3e-06 Identities = 51/179 (28%), Positives = 79/179 (44%), Gaps = 17/179 (9%) Query: 49 PVTLQCNLTS-SSHTLTYSYWTKNGVEL--SATRKNASNMEYRINKPRAEDSGEYHCVYH 105 P+TL C +T W K+G + S ++ S+ +I + D+G Y C+ Sbjct: 4095 PITLSCEADGLPPPDIT---WHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAA 4151 Query: 106 FVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164 V+ + +T + V P I + NE A + C + G P P W KK+N + Sbjct: 4152 NVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINW-KKDNVL-- 4208 Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223 + N G++ E Y EL + N+ + ED G Y C A NA G + L V H+ P Sbjct: 4209 -LANLLGKY---TAEPYGELILENV-VLEDSGFYTCVANNAAGEDTHTVSLTV--HVLP 4260 Score = 49.3 bits (116), Expect = 4e-06 Identities = 40/149 (26%), Positives = 62/149 (41%), Gaps = 5/149 (3%) Query: 88 RINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146 +I + + D+G+Y CV + T++V + P + G + T+ C Sbjct: 758 KIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQ 817 Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 GYP P WR+ +N M I + I++ L I+NL D G Y C A N Sbjct: 818 GYPEPTIKWRRLDN---MPIFSRPFSVSSISQLRTGALFILNLW-ASDKGTYICEAENQF 873 Query: 207 GSASVVTVLRVRSHLAPLWPFLGILAEII 235 G T + V +APL +A +I Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVI 902 Score = 48.5 bits (114), Expect = 6e-06 Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 21/188 (11%) Query: 26 GAAQNEPRIVTSE-EVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASN 84 G QN +++ E++ + + P TL H L K G+ +S R Sbjct: 2108 GEEQNVSVLISQAVELLCQSDAIPPPTL--TWLKDGHPLL----KKPGLSISENRS---- 2157 Query: 85 MEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKN--EGQDATM 141 +I + +D+G Y C + + N + + P+I G EG ++ Sbjct: 2158 -VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISL 2216 Query: 142 YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECN 201 C+S G P P+ IW+KK G P+ + ++ GR I++ +++I D Y C Sbjct: 2217 LCESSGIPPPNLIWKKK--GSPV-LTDSMGRVRILSGGRQLQISIAE---KSDAALYSCV 2270 Query: 202 ATNAIGSA 209 A+N G+A Sbjct: 2271 ASNVAGTA 2278 Score = 48.5 bits (114), Expect = 6e-06 Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 11/125 (8%) Query: 95 EDSGEYHCVYHFVSAPKANA-TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 153 EDSG Y CV + + + ++ V P T + N+G+ + CK+ G P P Sbjct: 4232 EDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291 Query: 154 IWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 213 W N +P + +G ++EL ++ ED G Y C A N++G + Sbjct: 4292 TWTFNNNIIPAHFDSVNG---------HSEL-VIERVSKEDSGTYVCTAENSVGFVKAIG 4341 Query: 214 VLRVR 218 + V+ Sbjct: 4342 FVYVK 4346 Score = 47.0 bits (110), Expect = 2e-05 Identities = 40/156 (25%), Positives = 67/156 (42%), Gaps = 12/156 (7%) Query: 68 WTKNGV--ELSATRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDI 124 W + GV E+S + N I ED+G+Y CV + + + ++ +++ P I Sbjct: 4383 WNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPII 4442 Query: 125 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 184 T N G + C++ G P P W ++ + + D +N + L Sbjct: 4443 TLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR--------VNVLSNNSL 4494 Query: 185 NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSH 220 I + Q ED E+EC A N +GS V + V+ H Sbjct: 4495 YIADAQ-KEDTSEFECVARNLMGSVLVRVPVIVQVH 4529 Score = 46.6 bits (109), Expect = 2e-05 Identities = 42/159 (26%), Positives = 65/159 (40%), Gaps = 20/159 (12%) Query: 68 WTKNGVEL---SATRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPD 123 W KNG+ L S R A+ RI + + D Y CV + + ++V A P+ Sbjct: 3376 WLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPN 3435 Query: 124 ITGHKRSENKN--EGQDATMYCKSVGYPHPDWIWRKKENGMPMDI---VNTSGRFFIINK 178 + +E +G +M C + G P P W + + +D V+T G + K Sbjct: 3436 MDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLK 3495 Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 TED G+Y C A+N G S +L+V Sbjct: 3496 AE-----------TEDSGKYTCIASNEAGEVSKHFILKV 3523 Score = 45.8 bits (107), Expect = 4e-05 Identities = 50/200 (25%), Positives = 84/200 (42%), Gaps = 26/200 (13%) Query: 49 PVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNASNME----YRINKPRAEDSGEYHCV 103 PV L+C + +LT W K+G +S+ + + + D+G Y CV Sbjct: 2028 PVRLECEARGIPAPSLT---WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCV 2084 Query: 104 YHFVSAPKA-NATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 162 + K + + V P+I G +++ + Q + C+S P P W K +G Sbjct: 2085 AVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLK--DGH 2142 Query: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLA 222 P ++ G + EN + L I + Q+ +D G Y C ATN G +++ Sbjct: 2143 P--LLKKPG---LSISENRSVLKIEDAQV-QDTGRYTCEATNVAGKTE-------KNYNV 2189 Query: 223 PLW--PFLGILAEIIILVVI 240 +W P +G E+ L VI Sbjct: 2190 NIWVPPNIGGSDELTQLTVI 2209 Score = 45.8 bits (107), Expect = 4e-05 Identities = 51/186 (27%), Positives = 76/186 (40%), Gaps = 21/186 (11%) Query: 27 AAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSAT---RKNAS 83 A +EPR +T ++R+ V TL+C S + W +NG L AT R + Sbjct: 3623 AGTDEPRDIT----VLRNRQV---TLECK--SDAVPPPVITWLRNGERLQATPRVRILSG 3673 Query: 84 NMEYRINKPRAEDSGEYHCVYHFVSAPKANATI-EVKAAPDITGHKRSENKNEGQDATMY 142 +IN D+ Y CV ++ I V P+I G +S + + Sbjct: 3674 GRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLE 3733 Query: 143 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNA 202 C + G P P WRK + R+ I+ L+I + +T D G Y C A Sbjct: 3734 CIAEGVPTPRITWRKDG----AVLAGNHARYSILENGF---LHIQSAHVT-DTGRYLCMA 3785 Query: 203 TNAIGS 208 TNA G+ Sbjct: 3786 TNAAGT 3791 Score = 45.4 bits (106), Expect = 5e-05 Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 26/172 (15%) Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVELS---ATRKNASNMEYRINKPRAEDSGEYHCVYHF 106 V+L C +S L W K+G +S + R + R+ + ED+G+Y CV Sbjct: 2404 VSLTCE--ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRN 2461 Query: 107 VSAPKANAT-IEVKAAPDITGHKRSENKN--EGQDATMYCKSVGYPHPDWIWRKKENGMP 163 + + + V P I G E+ E Q T+ C+ G P P+ W K +G P Sbjct: 2462 AAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK--DGQP 2519 Query: 164 MD-----IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210 + + + GRF L I N+Q+ G Y C A++ G S Sbjct: 2520 LQEDEAHHIISGGRF----------LQITNVQVPH-TGRYTCLASSPAGHKS 2560 Score = 45.4 bits (106), Expect = 5e-05 Identities = 50/198 (25%), Positives = 81/198 (40%), Gaps = 24/198 (12%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRI-- 89 P I E +I ++ PVTL C+ T W KN + +N+ ++E RI Sbjct: 3151 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIA--WLKNHKRI----ENSDSLEVRILS 3204 Query: 90 -------NKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNE--GQDA 139 + + DSG Y C+ + + + ++ P + G + + + G++ Sbjct: 3205 GGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENV 3264 Query: 140 TMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYE 199 + C + G P P W K +G P+ T I N + LNI +T D G+Y Sbjct: 3265 ELVCNANGIPTPLIQWLK--DGKPIASGETER---IRVSANGSTLNIYGA-LTSDTGKYT 3318 Query: 200 CNATNAIGSASVVTVLRV 217 C ATN G + L V Sbjct: 3319 CVATNPAGEEDRIFNLNV 3336 Score = 44.7 bits (104), Expect = 9e-05 Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 26/189 (13%) Query: 48 LPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNAS---NMEYRINKPRAEDSGEYHCVY 104 +PVTL C +S + W+K G +S + S + + P E+SGEY C Sbjct: 996 IPVTLPCK--ASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTA 1053 Query: 105 -HFVSAPKANATIEVKAAPDITGHKRSENKNE--------GQDATMYCKSVGYPHPDWIW 155 + K + V P + G +R ++++ G++ T+ C+ P P W Sbjct: 1054 TNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITW 1113 Query: 156 RKKENGM-PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTV 214 K+ + P +T F TE T D G Y C ATN G +V Sbjct: 1114 AKETQLISPFSPRHT---FLPSGSMKITETR------TSDSGMYLCVATNIAG--NVTQA 1162 Query: 215 LRVRSHLAP 223 +++ H+ P Sbjct: 1163 VKLNVHVPP 1171 Score = 44.3 bits (103), Expect = 1e-04 Identities = 33/144 (22%), Positives = 58/144 (40%), Gaps = 10/144 (6%) Query: 68 WTKNGVELSATRKNASNME---YRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPD 123 W K+G L+ S +E I D+G Y C+ + + ++V P Sbjct: 3746 WRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPS 3805 Query: 124 ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTE 183 I + T+ C++ G P P WRK NG +++ + +++ + Sbjct: 3806 IAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK--NGHLLNVDQNQNSYRLLSSGS--- 3860 Query: 184 LNIVNLQITEDPGEYECNATNAIG 207 L I++ + +D YEC TN G Sbjct: 3861 LVIISPSV-DDTATYECTVTNGAG 3883 Score = 43.5 bits (101), Expect = 2e-04 Identities = 47/196 (23%), Positives = 73/196 (37%), Gaps = 17/196 (8%) Query: 32 PRIVTSEEVIIRDSPVL-------PVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNAS 83 PR+ + + +D PV VTL C + S +T++ T+ S Sbjct: 1072 PRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLP 1131 Query: 84 NMEYRINKPRAEDSGEYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMY 142 + +I + R DSG Y CV ++ A + V P I + GQ + Sbjct: 1132 SGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIP 1191 Query: 143 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNA 202 C + G P P W K + M +D G + N + ++ D G Y C A Sbjct: 1192 CNAQGTPLPVITWSKGGSTMLVD-----GEHHVSNPDGTLSIDQAT---PSDAGIYTCVA 1243 Query: 203 TNAIGSASVVTVLRVR 218 TN G+ L V+ Sbjct: 1244 TNIAGTDETEITLHVQ 1259 Score = 40.8 bits (94), Expect = 0.001 Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 20/196 (10%) Query: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSAT---RKNASNMEY 87 EP + E S ++ L+ +S W K+G L T + Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL 3584 Query: 88 RINKPRAEDSGEYHCVYHFVSAPKAN----ATIEVKAAPDITG--HKRSENKNEGQDATM 141 RI+ + ED+G Y C+ S+P + + V P+I G R + T+ Sbjct: 3585 RISTAQVEDTGRYTCL---ASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 3641 Query: 142 YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECN 201 CKS P P W + NG + + + R I++ Y ++N +L D Y C Sbjct: 3642 ECKSDAVPPPVITWLR--NG---ERLQATPRVRILSGGRYLQINNADL---GDTANYTCV 3693 Query: 202 ATNAIGSASVVTVLRV 217 A+N G + +L V Sbjct: 3694 ASNIAGKTTREFILTV 3709 Score = 39.3 bits (90), Expect = 0.004 Identities = 41/193 (21%), Positives = 83/193 (43%), Gaps = 15/193 (7%) Query: 68 WTKNGVEL--SATRKNASNMEY-RINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPD 123 W K+ V++ S+T + +N + ++ + ED+G Y C + + I+V P Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPT 1453 Query: 124 ITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181 I G + +D + C+ G P PD W K +G P+ + + + + Sbjct: 1454 IIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFK--DGKPLFLGDPNVELL----DRG 1507 Query: 182 TELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVII 241 L++ N + D G Y+C +NA G + +++ ++ P + +I +L+ + Sbjct: 1508 QVLHLKNAR-RNDKGRYQCTVSNAAGKQA--KDIKLTIYIPPSIKGGNVTTDISVLINSL 1564 Query: 242 VVYEKRKRPDEVP 254 + E R +P Sbjct: 1565 IKLECETRGLPMP 1577 Score = 39.3 bits (90), Expect = 0.004 Identities = 45/179 (25%), Positives = 69/179 (38%), Gaps = 25/179 (13%) Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA---SNMEYRINKPRAEDSGEYHCV-Y 104 PV L+C ++ + + W K+ LS + I + D+G Y CV Sbjct: 1937 PVQLECK--AAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAI 1994 Query: 105 HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164 + A + +++V AP I+G + C++ G P P W K +G P+ Sbjct: 1995 NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLK--DGSPV 2052 Query: 165 DI------VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 V + GR L + + QI+ D G Y C A NA G LRV Sbjct: 2053 SSFSNGLQVLSGGRI----------LALTSAQIS-DTGRYTCVAVNAAGEKQRDIDLRV 2100 Score = 38.9 bits (89), Expect = 0.005 Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 14/127 (11%) Query: 96 DSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRS-ENKN--EGQDATMYCKSVGYPHP 151 D+G Y CV + + V A P I G+ RS EN + E ++ C++ G P P Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLP 2416 Query: 152 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-EDPGEYECNATNAIGSAS 210 W K +G P+ + N+ I++ L +Q T ED G+Y C NA G Sbjct: 2417 SITWFK--DGWPVSLSNSVR---ILSGGRMLRL----MQTTMEDAGQYTCVVRNAAGEER 2467 Query: 211 VVTVLRV 217 + L V Sbjct: 2468 KIFGLSV 2474 Score = 38.9 bits (89), Expect = 0.005 Identities = 51/193 (26%), Positives = 79/193 (40%), Gaps = 30/193 (15%) Query: 26 GAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSAT--RKNAS 83 GA + P VT V++ S ++ +C SS + W K+G L K S Sbjct: 2873 GANSDLPEEVT---VLVNKSALI----EC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLS 2923 Query: 84 NMEY-RINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNE--GQDA 139 N +I + D G Y CV + + K + V P + G K SEN Sbjct: 2924 NGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK-SENLTVVVNNFI 2982 Query: 140 TMYCKSVGYPHPDWIWRKKENGMPMD---IVNTSGRFFIINKENYTELNIVNLQITEDPG 196 ++ C+ G+P PD W K E + ++ ++ GR L I+ +++ D G Sbjct: 2983 SLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGR----------TLQIIRAKVS-DGG 3031 Query: 197 EYECNATNAIGSA 209 EY C A N G + Sbjct: 3032 EYTCIAINQAGES 3044 Score = 38.1 bits (87), Expect = 0.009 Identities = 41/157 (26%), Positives = 63/157 (40%), Gaps = 15/157 (9%) Query: 68 WTKNGVELSATRKN--ASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDI 124 WT N + + + + S+ I +D+G Y C+ + K N+T+ AP + Sbjct: 645 WTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKL 704 Query: 125 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 184 + G M CK+ G P P W K D+ F II+ L Sbjct: 705 MVVQSELLVALGDITVMECKTSGIPPPQVKWFKG------DLELRPSTFLIID----PLL 754 Query: 185 NIVNLQITE--DPGEYECNATNAIGSASVVTVLRVRS 219 ++ +Q T+ D G+Y C A N G A+ L V S Sbjct: 755 GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791 Score = 37.0 bits (84), Expect = 0.019 Identities = 33/125 (26%), Positives = 52/125 (41%), Gaps = 13/125 (10%) Query: 88 RINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSE----NKNEGQDATMY 142 +I + + D GEY C+ + K ++ V P I H N EG ++ Sbjct: 3021 QIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLE 3080 Query: 143 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNA 202 C+S P P W K NG ++ S I+ + L+I +++ D G+Y C A Sbjct: 3081 CESNAVPPPVITWYK--NGR---MITESTHVEIL--ADGQMLHIKKAEVS-DTGQYVCRA 3132 Query: 203 TNAIG 207 N G Sbjct: 3133 INVAG 3137 Score = 36.6 bits (83), Expect = 0.025 Identities = 54/210 (25%), Positives = 72/210 (34%), Gaps = 36/210 (17%) Query: 17 VSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELS 76 V S+ PGP T+ VI+ + TL C T W KNG L+ Sbjct: 3802 VPPSIAPGP----------TNMTVIVN----VQTTLACEATGIPKPSIN--WRKNGHLLN 3845 Query: 77 ATRKNASNMEYR--------INKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGH 127 + S YR I P +D+ Y C V + K + V+ P I Sbjct: 3846 VDQNQNS---YRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADE 3902 Query: 128 KRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIV 187 + A + C + G P P W K NG+ + G + I E+ Sbjct: 3903 PTDFLVTKHAPAVITCTASGVPFPSIHWTK--NGIRL---LPRGDGYRILSSGAIEILAT 3957 Query: 188 NLQITEDPGEYECNATNAIGSASVVTVLRV 217 L G Y C A NA GSA L V Sbjct: 3958 QLN---HAGRYTCVARNAAGSAHRHVTLHV 3984 Score = 36.2 bits (82), Expect = 0.033 Identities = 38/149 (25%), Positives = 56/149 (37%), Gaps = 15/149 (10%) Query: 68 WTKNGVELSATRKNASNME----YRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAP 122 W NG EL+ S +E I D+GEY CV + + ++V P Sbjct: 1300 WLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359 Query: 123 DITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 I ++ N + Q ++C+ G P P +W K D V + I N Sbjct: 1360 VIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYK-------DNVQVTESSTIQTVNN 1412 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSA 209 L + ED G Y C A N G++ Sbjct: 1413 GKILKLFRAT-PEDAGRYSCKAINIAGTS 1440 Score = 35.8 bits (81), Expect = 0.043 Identities = 52/221 (23%), Positives = 81/221 (36%), Gaps = 42/221 (19%) Query: 52 LQCNLTSSSHTLTYSYWTKNGV---ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVS 108 L C++T S W K+G E + + + I + + ++G Y C+ Sbjct: 1754 LDCHVTGSPPPTIM--WLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM----- 1806 Query: 109 APKANATIEVKAAPDITGHKRSENKNEG---------QDATMYCKSVGYPHPDWIWRKKE 159 AN + K ++T H K+ G + + C + G P+P W K + Sbjct: 1807 --AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 1864 Query: 160 NGMPMDI------VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 213 P++ + +SGR I K + ED G Y C ATNA G Sbjct: 1865 Q--PVNTAQGNLKIQSSGRVLQIAKT-----------LLEDAGRYTCVATNAAGETQQHI 1911 Query: 214 VLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVP 254 L V H P G + +LV V E + + VP Sbjct: 1912 QLHV--HEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVP 1950 Score = 35.4 bits (80), Expect = 0.057 Identities = 47/211 (22%), Positives = 86/211 (40%), Gaps = 38/211 (18%) Query: 24 GPGAAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSA---TR 79 GPG + E +I + + TL+C + S +L+ W K+G L + Sbjct: 2676 GPGLSPKEVKIKVNNTL----------TLECEAYAIPSASLS---WYKDGQPLKSDDHVN 2722 Query: 80 KNASNMEYRINKPRAEDSGEYHCVYHFVSAP-KANATIEVKAAPDIT-----GHKRSENK 133 A+ +I + + D+G Y CV ++ + + + ++ P G+ + Sbjct: 2723 IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGR 2782 Query: 134 N-EGQDA------TMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNI 186 N E +D ++YC++ P P W K +G P+ +S + I+ ++ Sbjct: 2783 NGEAKDVIINNPISLYCETNAAPPPTLTWYK--DGHPL---TSSDKVLILPGGRVLQIPR 2837 Query: 187 VNLQITEDPGEYECNATNAIGSASVVTVLRV 217 + ED G Y C A N G S+ +RV Sbjct: 2838 AKV---EDAGRYTCVAVNEAGEDSLQYDVRV 2865 Score = 35.0 bits (79), Expect = 0.074 Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 15/151 (9%) Query: 68 WTKNGVEL-SATRKNASNMEYRINKPRAE--DSGEYHC-VYHFVSAPKANATIEVKAAPD 123 W K+G + S+++ + ++ PRA+ DS Y C V + + + ++V P Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPM 1640 Query: 124 ITGHKRSENKNE---GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 I G+ + + T+ CK+ G P P W K +G+P+ N + R K Sbjct: 1641 IEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK--DGVPVK-ANDNIRIEAGGK-- 1695 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASV 211 +L I++ Q D G+Y C AT+ G + Sbjct: 1696 --KLEIMSAQ-EIDRGQYICVATSVAGEKEI 1723 Score = 32.0 bits (71), Expect = 0.63 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 15/134 (11%) Query: 94 AEDSGEYHC-VYHFVSAPKANATIEVKA--APDITGHKRSENKNEGQDATMYCKSV-GYP 149 A D G Y C + ++ T+ V AP I N EGQ T+ C + G P Sbjct: 859 ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNP 918 Query: 150 HPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 209 P+ W K + + + + + V LQ D GEY C A+N G+ Sbjct: 919 IPERRWIKNSAML------LQNPYITVRSDGSLHIERVQLQ---DGGEYTCVASNVAGTN 969 Query: 210 SVVTVLRVRSHLAP 223 + T + V H+ P Sbjct: 970 NKTTSVVV--HVLP 981 Score = 31.2 bits (69), Expect = 1.1 Identities = 33/155 (21%), Positives = 59/155 (38%), Gaps = 12/155 (7%) Query: 68 WTKNGVELSATR--KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDI 124 + +NGV L + K ++++ I K D G Y C+ +A +V P + Sbjct: 463 FVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPV 522 Query: 125 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYT-E 183 + G+ A + C + + W++ + V + I N + E Sbjct: 523 IQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRD-----VRLAEPARIRTLANLSLE 577 Query: 184 LNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 L V D GEY C ++ GS++ L V+ Sbjct: 578 LKSVKFN---DAGEYHCMVSSEGGSSAASVFLTVQ 609 >gi|126517478 peroxidasin homolog-like [Homo sapiens] Length = 1463 Score = 55.1 bits (131), Expect = 7e-08 Identities = 47/182 (25%), Positives = 78/182 (42%), Gaps = 17/182 (9%) Query: 39 EVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTK-NGVELSATRKNASNMEYRINKPRAEDS 97 EV+I S TL+C T H L WT+ NG+EL +R A++ + D Sbjct: 340 EVLIGTS----TTLECMATGHPHPLIT--WTRDNGLELDGSRHVATSSGLYLQNITQRDH 393 Query: 98 GEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWR 156 G + C + +A A I V+A P T + + E C++ G P P +W Sbjct: 394 GRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWT 453 Query: 157 KKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 216 K +P++ G+ +++ ++ D G+YEC A +++G V L Sbjct: 454 KTGGQLPVE-----GQHTVLSSGTLR----IDRAAQHDQGQYECQAVSSLGVKKVSVQLT 504 Query: 217 VR 218 V+ Sbjct: 505 VK 506 Score = 44.7 bits (104), Expect = 9e-05 Identities = 43/192 (22%), Positives = 76/192 (39%), Gaps = 25/192 (13%) Query: 34 IVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYS-----------YWTKNGVELSATRKNA 82 + + +I++ P VT + + H + + WTK G +L ++ Sbjct: 407 VQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHT 466 Query: 83 --SNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATIEVKAAPDITGHKRSENKNEGQ 137 S+ RI++ D G+Y C V T++ KA T + + G+ Sbjct: 467 VLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAVFTQLPQDTSVEVGK 526 Query: 138 DATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE 197 + + C + G P P W K+ G+ + SG+F + ++ T + D G Sbjct: 527 NINISCHAQGEPQPIITWNKE--GVQ---ITESGKFHVDDEGTLTIYDAG----FPDQGR 577 Query: 198 YECNATNAIGSA 209 YEC A N+ G A Sbjct: 578 YECVARNSFGLA 589 Score = 30.4 bits (67), Expect = 1.8 Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 21/102 (20%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 +P IT + G C++ G P P+ IW + + + E+ Sbjct: 233 SPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDL--------------ED 278 Query: 181 YTELNIVN---LQI----TEDPGEYECNATNAIGSASVVTVL 215 T LN+ + L I D G Y+C A N+ G A + + Sbjct: 279 DTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAM 320 >gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo sapiens] Length = 1386 Score = 54.7 bits (130), Expect = 9e-08 Identities = 47/185 (25%), Positives = 78/185 (42%), Gaps = 14/185 (7%) Query: 39 EVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA-SNMEYRINKPRAEDS 97 +V++ D+PV T C + W K EL R S+ I AED Sbjct: 267 QVVLADAPV---TFLCEVKGDPPPRLR--WRKEDGELPTGRYEIRSDHSLWIGHVSAEDE 321 Query: 98 GEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWR 156 G Y CV + V +A+ ++ V P + + + G+ C++ G P P W+ Sbjct: 322 GTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQ 381 Query: 157 KKENGM---PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 213 K+ + + P + +GRF + + +LNI +Q D G Y C A + GS Sbjct: 382 KEGSQVLLFPSQSLQPTGRFSVSPR---GQLNITAVQ-RGDAGYYVCQAVSVAGSILAKA 437 Query: 214 VLRVR 218 +L ++ Sbjct: 438 LLEIK 442 Score = 30.4 bits (67), Expect = 1.8 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 5/80 (6%) Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVN---TSGRFFIINKENYTELNIVNLQ 190 + G+ AT+ C++ G P P+ W K NG + V + R + + + + + Sbjct: 76 SRGEPATLPCRAEGRPRPNIEWYK--NGARVATVREDPRAHRLLLPSGALFFPRIVHGRR 133 Query: 191 ITEDPGEYECNATNAIGSAS 210 D G Y C A N +G+A+ Sbjct: 134 ARPDEGVYTCVARNYLGAAA 153 Score = 29.6 bits (65), Expect = 3.1 Identities = 32/134 (23%), Positives = 51/134 (38%), Gaps = 23/134 (17%) Query: 96 DSGEYHCVYHFVSAP-KANATIEVKAA------PDITGHKRSENKNEGQDATMYCKSVGY 148 D+G Y C V+ A A +E+K A P I ++ G + C+ G Sbjct: 418 DAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGN 477 Query: 149 PHPDWIWRKKENGMPMDIVN----TSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 P P W+K + D + +G +I N + D G Y C A + Sbjct: 478 PQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEM------------DMGFYSCVAKS 525 Query: 205 AIGSASVVTVLRVR 218 + G A+ L++R Sbjct: 526 STGEATWSGWLKMR 539 >gi|45594240 limbic system-associated membrane protein [Homo sapiens] Length = 338 Score = 54.3 bits (129), Expect = 1e-07 Identities = 44/135 (32%), Positives = 59/135 (43%), Gaps = 18/135 (13%) Query: 84 NMEY--RINKPRAEDSGEYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDAT 140 ++EY RI K D G Y C PK + + V+ P I+ NEG + T Sbjct: 91 SLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSNVT 150 Query: 141 MYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-EDPGEYE 199 + C + G P P WR + +GR F +E Y E+ L IT E G+YE Sbjct: 151 LVCMANGRPEPVITWRH---------LTPTGREF-EGEEEYLEI----LGITREQSGKYE 196 Query: 200 CNATNAIGSASVVTV 214 C A N + SA V V Sbjct: 197 CKAANEVSSADVKQV 211 Score = 47.0 bits (110), Expect = 2e-05 Identities = 34/123 (27%), Positives = 54/123 (43%), Gaps = 9/123 (7%) Query: 95 EDSGEYHC--VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPD 152 E SG+Y C SA + V P IT K +E G+ A++ C++ P PD Sbjct: 190 EQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNE-ATTGRQASLKCEASAVPAPD 248 Query: 153 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 212 + W + + +N++ I + E + L + N+ E G Y C A N +G + Sbjct: 249 FEWYRDDTR-----INSANGLEIKSTEGQSSLTVTNV-TEEHYGNYTCVAANKLGVTNAS 302 Query: 213 TVL 215 VL Sbjct: 303 LVL 305 >gi|19743806 roundabout 1 isoform b [Homo sapiens] Length = 1612 Score = 53.9 bits (128), Expect = 2e-07 Identities = 45/160 (28%), Positives = 66/160 (41%), Gaps = 9/160 (5%) Query: 68 WTKNGVELSATRKNA-SNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDIT 125 W K+ EL +R + +I K A D G Y CV + V +A+AT+ V+ P Sbjct: 256 WRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFV 315 Query: 126 GHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG---MPMDIVNTSGRFFIINKENYT 182 R + G+ T C++ G P P WR++ + +S RF + Sbjct: 316 VKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV---SQTG 372 Query: 183 ELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLA 222 +L I N+Q D G Y C N GS L V +A Sbjct: 373 DLTITNVQ-RSDVGYYICQTLNVAGSIITKAYLEVTDVIA 411 Score = 38.5 bits (88), Expect = 0.007 Identities = 45/174 (25%), Positives = 68/174 (39%), Gaps = 15/174 (8%) Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGVELSAT--RKNASNMEYRINKPRAEDSGEYHCVYHF 106 P ++C T S W K+G L R + I R D+G+Y CV Sbjct: 147 PAVMECQPPRGHPEPTIS-WKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTN 205 Query: 107 VSAPKANATIEVKAAPDITGHKRSENKNEGQD--ATMYCKSVGYPHPDWIWRKKENGMPM 164 + + + E+ + KR N D A C++ G P P WRK + +P Sbjct: 206 MVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP- 264 Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 R+ I ++++T L I + D G Y C A N +G A L V+ Sbjct: 265 -----KSRYEI--RDDHT-LKIRKV-TAGDMGSYTCVAENMVGKAEASATLTVQ 309 Score = 34.7 bits (78), Expect = 0.097 Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 1/89 (1%) Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181 P I H ++G+ AT+ CK+ G P P W K + D + ++ + Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88 Query: 182 TELNIVN-LQITEDPGEYECNATNAIGSA 209 L IV+ + D G Y C A N +G A Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEA 117 Score = 29.3 bits (64), Expect = 4.1 Identities = 41/196 (20%), Positives = 74/196 (37%), Gaps = 31/196 (15%) Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVE---------LSATRKNASNM-EYRINKPRAEDSGE 99 VT QC T + + W + G + S++R + S + I + D G Sbjct: 329 VTFQCEATGNPQPAIF--WRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGY 386 Query: 100 YHC-----VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDAT--MYCKSVGYPHPD 152 Y C ++ T + P + N+ D T + C + G P P Sbjct: 387 YICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPT 446 Query: 153 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE--DPGEYECNATNAIGSAS 210 +WRK +G+ +V+T ++ E ++ ++ + D G Y C A+ G A+ Sbjct: 447 ILWRK--DGV---LVSTQD-----SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEAT 496 Query: 211 VVTVLRVRSHLAPLWP 226 + V+ P+ P Sbjct: 497 WSAYIEVQEFGVPVQP 512 >gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo sapiens] Length = 790 Score = 53.9 bits (128), Expect = 2e-07 Identities = 45/185 (24%), Positives = 79/185 (42%), Gaps = 25/185 (13%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRKNAS---NMEY 87 P++V + V + SP L C L + + LT W ++ L A+ + ++ Sbjct: 517 PQLVPAPNVTV--SPGETAVLSCRVLGEAPYNLT---WVRDWRVLPASTGRVAQLADLSL 571 Query: 88 RINKPRAEDSGEYHCVYHFVSA-PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146 I+ D G Y CV + +A+ + V+ AP ++ H S++ ++G + + C + Sbjct: 572 EISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSAS 631 Query: 147 GYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203 GYP P W ++ + D V+ G I+ ED G Y C AT Sbjct: 632 GYPTPHISWSRESQALQEDSRIHVDAQGTL------------IIQGVAPEDAGNYSCQAT 679 Query: 204 NAIGS 208 N +G+ Sbjct: 680 NEVGT 684 Score = 38.9 bits (89), Expect = 0.005 Identities = 32/127 (25%), Positives = 51/127 (40%), Gaps = 18/127 (14%) Query: 95 EDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 153 ED+G Y C + V + T+ P ++ G++A + C++ G P P Sbjct: 669 EDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRV 728 Query: 154 IWRKKENGMPMDIV---NTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210 IW + G+ M + ++SG+ I + D G Y C A N +G AS Sbjct: 729 IWYR--GGLEMILAPEGSSSGKLRIPAAQE------------RDAGTYTCRAVNELGDAS 774 Query: 211 VVTVLRV 217 L V Sbjct: 775 AEIQLAV 781 Score = 29.3 bits (64), Expect = 4.1 Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 17/144 (11%) Query: 80 KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQD 138 + + N + I + + G Y C +A A I V P + + G+ Sbjct: 473 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGET 532 Query: 139 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----ED 194 A + C+ +G + W + +P ++GR +L ++L+I+ D Sbjct: 533 AVLSCRVLGEAPYNLTWVRDWRVLPA----STGRV--------AQLADLSLEISGIIPTD 580 Query: 195 PGEYECNATNAIGSASVVTVLRVR 218 G Y+C A+NA G L VR Sbjct: 581 GGRYQCVASNANGVTRASVWLLVR 604 >gi|4506569 roundabout 1 isoform a [Homo sapiens] Length = 1651 Score = 53.9 bits (128), Expect = 2e-07 Identities = 45/160 (28%), Positives = 66/160 (41%), Gaps = 9/160 (5%) Query: 68 WTKNGVELSATRKNA-SNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDIT 125 W K+ EL +R + +I K A D G Y CV + V +A+AT+ V+ P Sbjct: 295 WRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFV 354 Query: 126 GHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG---MPMDIVNTSGRFFIINKENYT 182 R + G+ T C++ G P P WR++ + +S RF + Sbjct: 355 VKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV---SQTG 411 Query: 183 ELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLA 222 +L I N+Q D G Y C N GS L V +A Sbjct: 412 DLTITNVQ-RSDVGYYICQTLNVAGSIITKAYLEVTDVIA 450 Score = 38.5 bits (88), Expect = 0.007 Identities = 45/174 (25%), Positives = 68/174 (39%), Gaps = 15/174 (8%) Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGVELSAT--RKNASNMEYRINKPRAEDSGEYHCVYHF 106 P ++C T S W K+G L R + I R D+G+Y CV Sbjct: 186 PAVMECQPPRGHPEPTIS-WKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTN 244 Query: 107 VSAPKANATIEVKAAPDITGHKRSENKNEGQD--ATMYCKSVGYPHPDWIWRKKENGMPM 164 + + + E+ + KR N D A C++ G P P WRK + +P Sbjct: 245 MVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP- 303 Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 R+ I ++++T L I + D G Y C A N +G A L V+ Sbjct: 304 -----KSRYEI--RDDHT-LKIRKV-TAGDMGSYTCVAENMVGKAEASATLTVQ 348 Score = 34.7 bits (78), Expect = 0.097 Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 1/89 (1%) Query: 122 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 181 P I H ++G+ AT+ CK+ G P P W K + D + ++ + Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 127 Query: 182 TELNIVN-LQITEDPGEYECNATNAIGSA 209 L IV+ + D G Y C A N +G A Sbjct: 128 FFLRIVHGRKSRPDEGVYVCVARNYLGEA 156 Score = 29.3 bits (64), Expect = 4.1 Identities = 41/196 (20%), Positives = 74/196 (37%), Gaps = 31/196 (15%) Query: 50 VTLQCNLTSSSHTLTYSYWTKNGVE---------LSATRKNASNM-EYRINKPRAEDSGE 99 VT QC T + + W + G + S++R + S + I + D G Sbjct: 368 VTFQCEATGNPQPAIF--WRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGY 425 Query: 100 YHC-----VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDAT--MYCKSVGYPHPD 152 Y C ++ T + P + N+ D T + C + G P P Sbjct: 426 YICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPT 485 Query: 153 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE--DPGEYECNATNAIGSAS 210 +WRK +G+ +V+T ++ E ++ ++ + D G Y C A+ G A+ Sbjct: 486 ILWRK--DGV---LVSTQD-----SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEAT 535 Query: 211 VVTVLRVRSHLAPLWP 226 + V+ P+ P Sbjct: 536 WSAYIEVQEFGVPVQP 551 >gi|134244585 putative neuronal cell adhesion molecule [Homo sapiens] Length = 814 Score = 53.5 bits (127), Expect = 2e-07 Identities = 64/214 (29%), Positives = 86/214 (40%), Gaps = 39/214 (18%) Query: 10 LALSLLLVSGSLLPGPG-----AAQNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLT 64 L L LLL+ LLP P +A+ + S++V + P P+ L C + + Sbjct: 20 LLLPLLLL---LLPAPSEGLGHSAELAFAVEPSDDVAV---PGQPIVLDCRVEGTPPVRI 73 Query: 65 YSYWTKNGVELSATRKNA--SNMEYRINKPRAE------DSGEYHCVYH--FVSAPKANA 114 W KNGVEL + + +N I R E D G+Y CV F A Sbjct: 74 T--WRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKA 131 Query: 115 TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFF 174 I+ D H ++ EG A C+ G P P W K N +P+D N Sbjct: 132 RIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEK--NRVPIDTDN------ 183 Query: 175 IINKENYTELNIVNLQIT----EDPGEYECNATN 204 E YT L LQIT ED G + C A+N Sbjct: 184 ----ERYTLLPKGVLQITGLRAEDGGIFHCVASN 213 Score = 36.6 bits (83), Expect = 0.025 Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Query: 112 ANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSG 171 A + V+A + H +S ++ G A C++ G P P W K NG ++ G Sbjct: 320 AQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLK--NG---QVLGPGG 374 Query: 172 RFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 + K N + L I + ED Y+C A N+ GS+ L V Sbjct: 375 HVRL--KNNNSTLTISGIG-PEDEAIYQCVAENSAGSSQASARLTV 417 >gi|110349717 titin isoform novex-2 [Homo sapiens] Length = 27118 Score = 53.1 bits (126), Expect = 3e-07 Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 16/160 (10%) Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATI--E 117 W NGVEL+ + + + S+ I + D G C+ + + + T+ E Sbjct: 26765 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE 26824 Query: 118 VKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIIN 177 + AP RS+N NEGQ+ C+ G P P+ W K N +P+ I S I Sbjct: 26825 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK--NNLPISI---SSNVSISR 26879 Query: 178 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 N L I N ++ D G+Y A N G S L V Sbjct: 26880 SRNVYSLEIRNASVS-DSGKYTIKAKNFRGQCSATASLMV 26918 Score = 39.7 bits (91), Expect = 0.003 Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 14/160 (8%) Query: 68 WTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCVY-HFVSAPKANATIEVKAA 121 W + G EL +RK + + R + ED G Y C+ + V + ++ + ++A Sbjct: 24261 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQAT 24320 Query: 122 PDI-TGHKRSENKNEGQDATM--YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178 P G+ E +T+ + +G P P W + ++ S I N Sbjct: 24321 PQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-----LLQNSENITIENT 24375 Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 E+YT L + N+Q G+Y+ +N G+ + + ++ Sbjct: 24376 EHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24415 Score = 38.1 bits (87), Expect = 0.009 Identities = 27/110 (24%), Positives = 46/110 (41%), Gaps = 15/110 (13%) Query: 114 ATIEVKAAPD-ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK----ENGMPMDIVN 168 A +E+ P + ++ EG+ T+ C GYP P W ++ E+ + I Sbjct: 888 APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 947 Query: 169 TSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 SG ++ +E + ED G + C+A N G+ S L V+ Sbjct: 948 QSGIARLMIREAF----------AEDSGRFTCSAVNEAGTVSTSCYLAVQ 987 Score = 37.7 bits (86), Expect = 0.011 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193 +EG+ T+ C G P P+ W G GRF I N ++ T L I+++Q + Sbjct: 27036 DEGKVLTVACAFTGEPTPEVTW---SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ-KQ 27091 Query: 194 DPGEYECNATNAIGSASVVTVLRVRS 219 D G Y + N GS S + +RS Sbjct: 27092 DGGLYTLSLGNEFGSDSATVNIHIRS 27117 Score = 37.0 bits (84), Expect = 0.019 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 6/99 (6%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP I + G+ A + C+ VG P PD W + + R + ++ + Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKEL------IQSRKYKMSSDG 24280 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 T V + ED G Y C ATN +G + L +++ Sbjct: 24281 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24319 Score = 36.6 bits (83), Expect = 0.025 Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 10/133 (7%) Query: 89 INKPRAED-SGEYHCVYHFVS---APKANATIEVKAAPDITGHKRSENKNEGQDATMYCK 144 I+K ED GEY C S A A T+ +AAP I G A C+ Sbjct: 4492 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCE 4551 Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 P+ + W K + S + I + + + L I+ Q+ D GEY C A+N Sbjct: 4552 IQSAPNVRFQWFKAGRE-----IYESDKCSIRSSKYISSLEILRTQVV-DCGEYTCKASN 4605 Query: 205 AIGSASVVTVLRV 217 GS S L V Sbjct: 4606 EYGSVSCTATLTV 4618 Score = 35.4 bits (80), Expect = 0.057 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%) Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169 PK++ I+ AP R+ N +AT+ CK G+P P W ++ + D + Sbjct: 24614 PKSDVPIQ---APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKY 24670 Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 + F K Y +L I ++ +D Y+ ATN GS S L V Sbjct: 24671 RIQEF---KGGYHQLIIASV-TDDDATVYQVRATNQGGSVSGTASLEV 24714 Score = 34.7 bits (78), Expect = 0.097 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 5/85 (5%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 EGQ A K VG P P+ W + D + ++ KE+ T+ I+ D Sbjct: 1424 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK-----VVIKEDGTQSLIIVPATPSD 1478 Query: 195 PGEYECNATNAIGSASVVTVLRVRS 219 GE+ A N G +S+ +L V + Sbjct: 1479 SGEWTVVAQNRAGRSSISVILTVEA 1503 Score = 34.7 bits (78), Expect = 0.097 Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 33/155 (21%) Query: 68 WTKNGVELSATRKNASNMEYRIN-------KPRAEDSGEYHCVYHFVSAPK-ANATIEVK 119 W +N + + K+ E +I+ KPR D GEY F++ K A A +E+ Sbjct: 6639 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR--DQGEYR----FIAKDKEARAKLELA 6692 Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTS--------- 170 AAP I + + G+ TM YP + W K+ + ++T+ Sbjct: 6693 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRIL 6752 Query: 171 -------GRFFII--NKENYTELNIVNLQITEDPG 196 GR+ I+ NK E +NL++ + PG Sbjct: 6753 EAKKGDKGRYKIVLQNKHGKAE-GFINLKVIDVPG 6786 Score = 33.1 bits (74), Expect = 0.28 Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 5/83 (6%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 +G A VG P P W K+ + TS + II+ N + IVN ED Sbjct: 3780 QGLPAIFEYTVVGEPAPTVTWFKENKQLC-----TSVYYTIIHNPNGSGTFIVNDPQRED 3834 Query: 195 PGEYECNATNAIGSASVVTVLRV 217 G Y C A N +G ++ L V Sbjct: 3835 SGLYICKAENMLGESTCAAELLV 3857 Score = 32.3 bits (72), Expect = 0.48 Identities = 30/145 (20%), Positives = 57/145 (39%), Gaps = 10/145 (6%) Query: 74 ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENK 133 +++ TR++ S+ E+ + + E + + K T+ + I RS Sbjct: 26212 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR----ILTKPRSMTV 26267 Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193 EG+ A C + G P P W +K +++TS R + + + I ++Q Sbjct: 26268 YEGESARFSCDTDGEPVPTVTWLRKG-----QVLSTSARHQVTTTKYKSTFEISSVQ-AS 26321 Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218 D G Y N+ G L ++ Sbjct: 26322 DEGNYSVVVENSEGKQEAEFTLTIQ 26346 Score = 31.6 bits (70), Expect = 0.82 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%) Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178 K PDI + EG+ A C+ GYP P W NG ++ S R F + Sbjct: 1792 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL--NG---QLIRKSKR-FRVRY 1845 Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIG 207 + L+IV+ + + D GE + A N G Sbjct: 1846 DGIHYLDIVDCK-SYDTGEVKVTAENPEG 1873 Score = 31.6 bits (70), Expect = 0.82 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 7/84 (8%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE-NYTELNIVNLQITE 193 EGQ + G P P W K +G P+ + II++ +Y L+I + + E Sbjct: 25503 EGQSVCFEIRVSGIPPPTLKWEK--DGQPLSL---GPNIEIIHEGLDYYALHIRDT-LPE 25556 Query: 194 DPGEYECNATNAIGSASVVTVLRV 217 D G Y ATN GS S L+V Sbjct: 25557 DTGYYRVTATNTAGSTSCQAHLQV 25580 Score = 31.2 bits (69), Expect = 1.1 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%) Query: 136 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-ED 194 G+D + G P P WRK E + D R+ I N ++ + L I Q+T D Sbjct: 20981 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-----ARYSIENTDSSSLLTIP--QVTRND 21033 Query: 195 PGEYECNATNAIGSASVVTV 214 G+Y N +G TV Sbjct: 21034 TGKYILTIENGVGEPKSSTV 21053 Score = 30.8 bits (68), Expect = 1.4 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 5/99 (5%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP I +S+ +G DA + VG P P+ W K NG+ ++ + ++ ++N Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK--NGVKIE--RSDRIYWYWPEDN 2086 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 EL ++ ED A N G S L V++ Sbjct: 2087 VCEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2124 Score = 30.8 bits (68), Expect = 1.4 Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 16/162 (9%) Query: 60 SHTLTYSYWTKNGVELSATRKNASNMEYRINK-----PRAEDSGEYHCVYHFVSAPKANA 114 SH S W KNGVE+ + K ++ ++++ EDS EY V + +A Sbjct: 2860 SHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV---CGNDQVSA 2916 Query: 115 TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFF 174 T+ V P + + E +D + +V Y + W K NG+ + ++ + Sbjct: 2917 TLTV--TPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLK--NGVE---IKSTDKCQ 2969 Query: 175 IINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 216 + K+ LNI N+ D +Y A A +A++ R Sbjct: 2970 MRTKKLTHSLNIRNVHF-GDAADYTFVAGKATSTATLYVEAR 3010 Score = 30.8 bits (68), Expect = 1.4 Identities = 42/179 (23%), Positives = 66/179 (36%), Gaps = 38/179 (21%) Query: 51 TLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYH--------- 101 TL C +T H W + G E+ A ++YRI E G YH Sbjct: 24641 TLVCKVTG--HPKPIVKWYRQGKEIIA-----DGLKYRIQ----EFKGGYHQLIIASVTD 24689 Query: 102 ---CVYHFVSAPKAN-----ATIEVKAAPDITGHKRSENKN-----EGQDATMYCKSVGY 148 VY + + A++EV+ I K E G+ ++ G Sbjct: 24690 DDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGK 24749 Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207 P P W+K + D+++ +G + +I ++T L N +D G Y A N G Sbjct: 24750 PDPVITWQKGQ-----DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 24803 Score = 30.8 bits (68), Expect = 1.4 Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 8/110 (7%) Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169 PKA I K P I + + A K+ G P P IW K + T Sbjct: 26537 PKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAI------T 26588 Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 G + ++++ ++ T D G Y C N+ GS S L +++ Sbjct: 26589 QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26638 Score = 30.4 bits (67), Expect = 1.8 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 7/62 (11%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G P P +W K+E + D R I N +EL I+ + +D G Y ATN+ Sbjct: 8825 GRPVPTKVWTKEEGELDKD------RVVIDNVGTKSEL-IIKDALRKDHGRYVITATNSC 8877 Query: 207 GS 208 GS Sbjct: 8878 GS 8879 Score = 29.6 bits (65), Expect = 3.1 Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 6/99 (6%) Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 179 A P+ +S +G + + G P P + + +G + S F I++E Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQ----SSLDFQISQE 155 Query: 180 NYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 ++ ED G Y NATN++G A+ L V+ Sbjct: 156 GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 29.3 bits (64), Expect = 4.1 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 EG T +CK GYP P W K +G + F+ + + +V + ED Sbjct: 1258 EGMGVTFHCKMSGYPLPKIAWYK--DGKRIKHGERYQMDFLQDGRASLRIPVV---LPED 1312 Query: 195 PGEYECNATNAIGSA 209 G Y A+N G+A Sbjct: 1313 EGIYTAFASNIKGNA 1327 Score = 29.3 bits (64), Expect = 4.1 Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G P P W + + D + + +N++ + + + D GEY+ +NA Sbjct: 11231 GVPVPTAKWTTDGSEIKTD------EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 11284 Query: 207 GSASVVTVLRV 217 GS +V L V Sbjct: 11285 GSKTVAVHLTV 11295 Score = 28.9 bits (63), Expect = 5.3 Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G PHP W+K E+ ++V +S ++K + + + I+ +D G Y A N+ Sbjct: 12619 GKPHPTCKWKKGED----EVVTSS--HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSS 12672 Query: 207 GS 208 G+ Sbjct: 12673 GT 12674 Score = 28.5 bits (62), Expect = 6.9 Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 4/103 (3%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP T +S EG AT G+P P+ W + +G + G I + Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFR--DGQVISTSTLPG-VQISFSDG 61 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223 +L I + + G Y ATN G A+ L V++ AP Sbjct: 62 RAKLTIPAVT-KANSGRYSLKATNGSGQATSTAELLVKAETAP 103 Score = 28.1 bits (61), Expect = 9.0 Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 6/71 (8%) Query: 96 DSGEYHCVYH------FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 149 DSGE+ V +S +E + P ++ N EG M ++ G P Sbjct: 1478 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1537 Query: 150 HPDWIWRKKEN 160 +PD +W K + Sbjct: 1538 NPDIVWLKNSD 1548 Score = 28.1 bits (61), Expect = 9.0 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 147 GYPHPDWIWRKKENGM--PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 G P P W K E + P D + + + + E TEL+I + ED G Y A+N Sbjct: 9119 GLPMPKIEWSKNETVIEKPTDALQIT-KEEVSRSEAKTELSIPKA-VREDKGTYTVTASN 9176 Query: 205 AIGS 208 +GS Sbjct: 9177 RLGS 9180 >gi|110349713 titin isoform novex-1 [Homo sapiens] Length = 27051 Score = 53.1 bits (126), Expect = 3e-07 Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 16/160 (10%) Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATI--E 117 W NGVEL+ + + + S+ I + D G C+ + + + T+ E Sbjct: 26698 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE 26757 Query: 118 VKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIIN 177 + AP RS+N NEGQ+ C+ G P P+ W K N +P+ I S I Sbjct: 26758 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK--NNLPISI---SSNVSISR 26812 Query: 178 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 N L I N ++ D G+Y A N G S L V Sbjct: 26813 SRNVYSLEIRNASVS-DSGKYTIKAKNFRGQCSATASLMV 26851 Score = 39.7 bits (91), Expect = 0.003 Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 14/160 (8%) Query: 68 WTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCVY-HFVSAPKANATIEVKAA 121 W + G EL +RK + + R + ED G Y C+ + V + ++ + ++A Sbjct: 24194 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQAT 24253 Query: 122 PDI-TGHKRSENKNEGQDATM--YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178 P G+ E +T+ + +G P P W + ++ S I N Sbjct: 24254 PQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-----LLQNSENITIENT 24308 Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 E+YT L + N+Q G+Y+ +N G+ + + ++ Sbjct: 24309 EHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24348 Score = 38.1 bits (87), Expect = 0.009 Identities = 27/110 (24%), Positives = 46/110 (41%), Gaps = 15/110 (13%) Query: 114 ATIEVKAAPD-ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK----ENGMPMDIVN 168 A +E+ P + ++ EG+ T+ C GYP P W ++ E+ + I Sbjct: 888 APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 947 Query: 169 TSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 SG ++ +E + ED G + C+A N G+ S L V+ Sbjct: 948 QSGIARLMIREAF----------AEDSGRFTCSAVNEAGTVSTSCYLAVQ 987 Score = 37.7 bits (86), Expect = 0.011 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193 +EG+ T+ C G P P+ W G GRF I N ++ T L I+++Q + Sbjct: 26969 DEGKVLTVACAFTGEPTPEVTW---SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ-KQ 27024 Query: 194 DPGEYECNATNAIGSASVVTVLRVRS 219 D G Y + N GS S + +RS Sbjct: 27025 DGGLYTLSLGNEFGSDSATVNIHIRS 27050 Score = 37.0 bits (84), Expect = 0.019 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 6/99 (6%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP I + G+ A + C+ VG P PD W + + R + ++ + Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKEL------IQSRKYKMSSDG 24213 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 T V + ED G Y C ATN +G + L +++ Sbjct: 24214 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24252 Score = 36.6 bits (83), Expect = 0.025 Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 10/133 (7%) Query: 89 INKPRAED-SGEYHCVYHFVS---APKANATIEVKAAPDITGHKRSENKNEGQDATMYCK 144 I+K ED GEY C S A A T+ +AAP I G A C+ Sbjct: 4425 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCE 4484 Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 P+ + W K + S + I + + + L I+ Q+ D GEY C A+N Sbjct: 4485 IQSAPNVRFQWFKAGRE-----IYESDKCSIRSSKYISSLEILRTQVV-DCGEYTCKASN 4538 Query: 205 AIGSASVVTVLRV 217 GS S L V Sbjct: 4539 EYGSVSCTATLTV 4551 Score = 35.4 bits (80), Expect = 0.057 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%) Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169 PK++ I+ AP R+ N +AT+ CK G+P P W ++ + D + Sbjct: 24547 PKSDVPIQ---APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKY 24603 Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 + F K Y +L I ++ +D Y+ ATN GS S L V Sbjct: 24604 RIQEF---KGGYHQLIIASV-TDDDATVYQVRATNQGGSVSGTASLEV 24647 Score = 34.7 bits (78), Expect = 0.097 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 5/85 (5%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 EGQ A K VG P P+ W + D + ++ KE+ T+ I+ D Sbjct: 1424 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK-----VVIKEDGTQSLIIVPATPSD 1478 Query: 195 PGEYECNATNAIGSASVVTVLRVRS 219 GE+ A N G +S+ +L V + Sbjct: 1479 SGEWTVVAQNRAGRSSISVILTVEA 1503 Score = 34.7 bits (78), Expect = 0.097 Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 33/155 (21%) Query: 68 WTKNGVELSATRKNASNMEYRIN-------KPRAEDSGEYHCVYHFVSAPK-ANATIEVK 119 W +N + + K+ E +I+ KPR D GEY F++ K A A +E+ Sbjct: 6572 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR--DQGEYR----FIAKDKEARAKLELA 6625 Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTS--------- 170 AAP I + + G+ TM YP + W K+ + ++T+ Sbjct: 6626 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRIL 6685 Query: 171 -------GRFFII--NKENYTELNIVNLQITEDPG 196 GR+ I+ NK E +NL++ + PG Sbjct: 6686 EAKKGDKGRYKIVLQNKHGKAE-GFINLKVIDVPG 6719 Score = 33.1 bits (74), Expect = 0.28 Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 5/83 (6%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 +G A VG P P W K+ + TS + II+ N + IVN ED Sbjct: 3713 QGLPAIFEYTVVGEPAPTVTWFKENKQLC-----TSVYYTIIHNPNGSGTFIVNDPQRED 3767 Query: 195 PGEYECNATNAIGSASVVTVLRV 217 G Y C A N +G ++ L V Sbjct: 3768 SGLYICKAENMLGESTCAAELLV 3790 Score = 32.3 bits (72), Expect = 0.48 Identities = 30/145 (20%), Positives = 57/145 (39%), Gaps = 10/145 (6%) Query: 74 ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENK 133 +++ TR++ S+ E+ + + E + + K T+ + I RS Sbjct: 26145 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR----ILTKPRSMTV 26200 Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193 EG+ A C + G P P W +K +++TS R + + + I ++Q Sbjct: 26201 YEGESARFSCDTDGEPVPTVTWLRKG-----QVLSTSARHQVTTTKYKSTFEISSVQ-AS 26254 Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218 D G Y N+ G L ++ Sbjct: 26255 DEGNYSVVVENSEGKQEAEFTLTIQ 26279 Score = 31.6 bits (70), Expect = 0.82 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%) Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178 K PDI + EG+ A C+ GYP P W NG ++ S R F + Sbjct: 1792 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL--NG---QLIRKSKR-FRVRY 1845 Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIG 207 + L+IV+ + + D GE + A N G Sbjct: 1846 DGIHYLDIVDCK-SYDTGEVKVTAENPEG 1873 Score = 31.6 bits (70), Expect = 0.82 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 7/84 (8%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE-NYTELNIVNLQITE 193 EGQ + G P P W K +G P+ + II++ +Y L+I + + E Sbjct: 25436 EGQSVCFEIRVSGIPPPTLKWEK--DGQPLSL---GPNIEIIHEGLDYYALHIRDT-LPE 25489 Query: 194 DPGEYECNATNAIGSASVVTVLRV 217 D G Y ATN GS S L+V Sbjct: 25490 DTGYYRVTATNTAGSTSCQAHLQV 25513 Score = 31.2 bits (69), Expect = 1.1 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%) Query: 136 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-ED 194 G+D + G P P WRK E + D R+ I N ++ + L I Q+T D Sbjct: 20914 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-----ARYSIENTDSSSLLTIP--QVTRND 20966 Query: 195 PGEYECNATNAIGSASVVTV 214 G+Y N +G TV Sbjct: 20967 TGKYILTIENGVGEPKSSTV 20986 Score = 30.8 bits (68), Expect = 1.4 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 5/99 (5%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP I +S+ +G DA + VG P P+ W K NG+ ++ + ++ ++N Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK--NGVKIE--RSDRIYWYWPEDN 2086 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 EL ++ ED A N G S L V++ Sbjct: 2087 VCEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2124 Score = 30.8 bits (68), Expect = 1.4 Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 16/162 (9%) Query: 60 SHTLTYSYWTKNGVELSATRKNASNMEYRINK-----PRAEDSGEYHCVYHFVSAPKANA 114 SH S W KNGVE+ + K ++ ++++ EDS EY V + +A Sbjct: 2860 SHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV---CGNDQVSA 2916 Query: 115 TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFF 174 T+ V P + + E +D + +V Y + W K NG+ + ++ + Sbjct: 2917 TLTV--TPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLK--NGVE---IKSTDKCQ 2969 Query: 175 IINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 216 + K+ LNI N+ D +Y A A +A++ R Sbjct: 2970 MRTKKLTHSLNIRNVHF-GDAADYTFVAGKATSTATLYVEAR 3010 Score = 30.8 bits (68), Expect = 1.4 Identities = 42/179 (23%), Positives = 66/179 (36%), Gaps = 38/179 (21%) Query: 51 TLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYH--------- 101 TL C +T H W + G E+ A ++YRI E G YH Sbjct: 24574 TLVCKVTG--HPKPIVKWYRQGKEIIA-----DGLKYRIQ----EFKGGYHQLIIASVTD 24622 Query: 102 ---CVYHFVSAPKAN-----ATIEVKAAPDITGHKRSENKN-----EGQDATMYCKSVGY 148 VY + + A++EV+ I K E G+ ++ G Sbjct: 24623 DDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGK 24682 Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207 P P W+K + D+++ +G + +I ++T L N +D G Y A N G Sbjct: 24683 PDPVITWQKGQ-----DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 24736 Score = 30.8 bits (68), Expect = 1.4 Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 8/110 (7%) Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169 PKA I K P I + + A K+ G P P IW K + T Sbjct: 26470 PKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAI------T 26521 Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 G + ++++ ++ T D G Y C N+ GS S L +++ Sbjct: 26522 QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26571 Score = 30.4 bits (67), Expect = 1.8 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 7/62 (11%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G P P +W K+E + D R I N +EL I+ + +D G Y ATN+ Sbjct: 8758 GRPVPTKVWTKEEGELDKD------RVVIDNVGTKSEL-IIKDALRKDHGRYVITATNSC 8810 Query: 207 GS 208 GS Sbjct: 8811 GS 8812 Score = 30.0 bits (66), Expect = 2.4 Identities = 19/84 (22%), Positives = 33/84 (39%), Gaps = 4/84 (4%) Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193 + G+ + + G P P+ W + I+ T F + L ++ +E Sbjct: 3431 HNGETVRFHARVSGIPKPEIQWFHNQQL----ILPTKDVVFHFEESTGMALMLIVDAYSE 3486 Query: 194 DPGEYECNATNAIGSASVVTVLRV 217 G+Y C A N+ G A+ L V Sbjct: 3487 HAGQYSCKAANSAGEATCAATLTV 3510 Score = 29.6 bits (65), Expect = 3.1 Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 6/99 (6%) Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 179 A P+ +S +G + + G P P + + +G + S F I++E Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQ----SSLDFQISQE 155 Query: 180 NYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 ++ ED G Y NATN++G A+ L V+ Sbjct: 156 GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 29.3 bits (64), Expect = 4.1 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 EG T +CK GYP P W K +G + F+ + + +V + ED Sbjct: 1258 EGMGVTFHCKMSGYPLPKIAWYK--DGKRIKHGERYQMDFLQDGRASLRIPVV---LPED 1312 Query: 195 PGEYECNATNAIGSA 209 G Y A+N G+A Sbjct: 1313 EGIYTAFASNIKGNA 1327 Score = 29.3 bits (64), Expect = 4.1 Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G P P W + + D + + +N++ + + + D GEY+ +NA Sbjct: 11164 GVPVPTAKWTTDGSEIKTD------EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 11217 Query: 207 GSASVVTVLRV 217 GS +V L V Sbjct: 11218 GSKTVAVHLTV 11228 Score = 28.9 bits (63), Expect = 5.3 Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G PHP W+K E+ ++V +S ++K + + + I+ +D G Y A N+ Sbjct: 12552 GKPHPTCKWKKGED----EVVTSS--HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSS 12605 Query: 207 GS 208 G+ Sbjct: 12606 GT 12607 Score = 28.5 bits (62), Expect = 6.9 Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 4/103 (3%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP T +S EG AT G+P P+ W + +G + G I + Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFR--DGQVISTSTLPG-VQISFSDG 61 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223 +L I + + G Y ATN G A+ L V++ AP Sbjct: 62 RAKLTIPAVT-KANSGRYSLKATNGSGQATSTAELLVKAETAP 103 Score = 28.1 bits (61), Expect = 9.0 Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 6/71 (8%) Query: 96 DSGEYHCVYH------FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 149 DSGE+ V +S +E + P ++ N EG M ++ G P Sbjct: 1478 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1537 Query: 150 HPDWIWRKKEN 160 +PD +W K + Sbjct: 1538 NPDIVWLKNSD 1548 Score = 28.1 bits (61), Expect = 9.0 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 147 GYPHPDWIWRKKENGM--PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 G P P W K E + P D + + + + E TEL+I + ED G Y A+N Sbjct: 9052 GLPMPKIEWSKNETVIEKPTDALQIT-KEEVSRSEAKTELSIPKA-VREDKGTYTVTASN 9109 Query: 205 AIGS 208 +GS Sbjct: 9110 RLGS 9113 >gi|110349715 titin isoform N2-B [Homo sapiens] Length = 26926 Score = 53.1 bits (126), Expect = 3e-07 Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 16/160 (10%) Query: 68 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATI--E 117 W NGVEL+ + + + S+ I + D G C+ + + + T+ E Sbjct: 26573 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE 26632 Query: 118 VKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIIN 177 + AP RS+N NEGQ+ C+ G P P+ W K N +P+ I S I Sbjct: 26633 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK--NNLPISI---SSNVSISR 26687 Query: 178 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 N L I N ++ D G+Y A N G S L V Sbjct: 26688 SRNVYSLEIRNASVS-DSGKYTIKAKNFRGQCSATASLMV 26726 Score = 39.7 bits (91), Expect = 0.003 Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 14/160 (8%) Query: 68 WTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCVY-HFVSAPKANATIEVKAA 121 W + G EL +RK + + R + ED G Y C+ + V + ++ + ++A Sbjct: 24069 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQAT 24128 Query: 122 PDI-TGHKRSENKNEGQDATM--YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178 P G+ E +T+ + +G P P W + ++ S I N Sbjct: 24129 PQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-----LLQNSENITIENT 24183 Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 E+YT L + N+Q G+Y+ +N G+ + + ++ Sbjct: 24184 EHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24223 Score = 38.1 bits (87), Expect = 0.009 Identities = 27/110 (24%), Positives = 46/110 (41%), Gaps = 15/110 (13%) Query: 114 ATIEVKAAPD-ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK----ENGMPMDIVN 168 A +E+ P + ++ EG+ T+ C GYP P W ++ E+ + I Sbjct: 888 APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 947 Query: 169 TSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 SG ++ +E + ED G + C+A N G+ S L V+ Sbjct: 948 QSGIARLMIREAF----------AEDSGRFTCSAVNEAGTVSTSCYLAVQ 987 Score = 37.7 bits (86), Expect = 0.011 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193 +EG+ T+ C G P P+ W G GRF I N ++ T L I+++Q + Sbjct: 26844 DEGKVLTVACAFTGEPTPEVTW---SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ-KQ 26899 Query: 194 DPGEYECNATNAIGSASVVTVLRVRS 219 D G Y + N GS S + +RS Sbjct: 26900 DGGLYTLSLGNEFGSDSATVNIHIRS 26925 Score = 37.0 bits (84), Expect = 0.019 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 6/99 (6%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP I + G+ A + C+ VG P PD W + + R + ++ + Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKEL------IQSRKYKMSSDG 24088 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 T V + ED G Y C ATN +G + L +++ Sbjct: 24089 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24127 Score = 36.6 bits (83), Expect = 0.025 Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 10/133 (7%) Query: 89 INKPRAED-SGEYHCVYHFVS---APKANATIEVKAAPDITGHKRSENKNEGQDATMYCK 144 I+K ED GEY C S A A T+ +AAP I G A C+ Sbjct: 4300 IDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCE 4359 Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 P+ + W K + S + I + + + L I+ Q+ D GEY C A+N Sbjct: 4360 IQSAPNVRFQWFKAGRE-----IYESDKCSIRSSKYISSLEILRTQVV-DCGEYTCKASN 4413 Query: 205 AIGSASVVTVLRV 217 GS S L V Sbjct: 4414 EYGSVSCTATLTV 4426 Score = 35.4 bits (80), Expect = 0.057 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%) Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169 PK++ I+ AP R+ N +AT+ CK G+P P W ++ + D + Sbjct: 24422 PKSDVPIQ---APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKY 24478 Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 217 + F K Y +L I ++ +D Y+ ATN GS S L V Sbjct: 24479 RIQEF---KGGYHQLIIASV-TDDDATVYQVRATNQGGSVSGTASLEV 24522 Score = 34.7 bits (78), Expect = 0.097 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 5/85 (5%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 EGQ A K VG P P+ W + D + ++ KE+ T+ I+ D Sbjct: 1424 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHK-----VVIKEDGTQSLIIVPATPSD 1478 Query: 195 PGEYECNATNAIGSASVVTVLRVRS 219 GE+ A N G +S+ +L V + Sbjct: 1479 SGEWTVVAQNRAGRSSISVILTVEA 1503 Score = 34.7 bits (78), Expect = 0.097 Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 33/155 (21%) Query: 68 WTKNGVELSATRKNASNMEYRIN-------KPRAEDSGEYHCVYHFVSAPK-ANATIEVK 119 W +N + + K+ E +I+ KPR D GEY F++ K A A +E+ Sbjct: 6447 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR--DQGEYR----FIAKDKEARAKLELA 6500 Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTS--------- 170 AAP I + + G+ TM YP + W K+ + ++T+ Sbjct: 6501 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRIL 6560 Query: 171 -------GRFFII--NKENYTELNIVNLQITEDPG 196 GR+ I+ NK E +NL++ + PG Sbjct: 6561 EAKKGDKGRYKIVLQNKHGKAE-GFINLKVIDVPG 6594 Score = 33.1 bits (74), Expect = 0.28 Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 5/83 (6%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 +G A VG P P W K+ + TS + II+ N + IVN ED Sbjct: 3588 QGLPAIFEYTVVGEPAPTVTWFKENKQLC-----TSVYYTIIHNPNGSGTFIVNDPQRED 3642 Query: 195 PGEYECNATNAIGSASVVTVLRV 217 G Y C A N +G ++ L V Sbjct: 3643 SGLYICKAENMLGESTCAAELLV 3665 Score = 32.3 bits (72), Expect = 0.48 Identities = 30/145 (20%), Positives = 57/145 (39%), Gaps = 10/145 (6%) Query: 74 ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENK 133 +++ TR++ S+ E+ + + E + + K T+ + I RS Sbjct: 26020 QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAAR----ILTKPRSMTV 26075 Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193 EG+ A C + G P P W +K +++TS R + + + I ++Q Sbjct: 26076 YEGESARFSCDTDGEPVPTVTWLRKG-----QVLSTSARHQVTTTKYKSTFEISSVQ-AS 26129 Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218 D G Y N+ G L ++ Sbjct: 26130 DEGNYSVVVENSEGKQEAEFTLTIQ 26154 Score = 31.6 bits (70), Expect = 0.82 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%) Query: 119 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 178 K PDI + EG+ A C+ GYP P W NG ++ S R F + Sbjct: 1792 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL--NG---QLIRKSKR-FRVRY 1845 Query: 179 ENYTELNIVNLQITEDPGEYECNATNAIG 207 + L+IV+ + + D GE + A N G Sbjct: 1846 DGIHYLDIVDCK-SYDTGEVKVTAENPEG 1873 Score = 31.6 bits (70), Expect = 0.82 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 7/84 (8%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE-NYTELNIVNLQITE 193 EGQ + G P P W K +G P+ + II++ +Y L+I + + E Sbjct: 25311 EGQSVCFEIRVSGIPPPTLKWEK--DGQPLSL---GPNIEIIHEGLDYYALHIRDT-LPE 25364 Query: 194 DPGEYECNATNAIGSASVVTVLRV 217 D G Y ATN GS S L+V Sbjct: 25365 DTGYYRVTATNTAGSTSCQAHLQV 25388 Score = 31.2 bits (69), Expect = 1.1 Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%) Query: 136 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-ED 194 G+D + G P P WRK E + D R+ I N ++ + L I Q+T D Sbjct: 20789 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-----ARYSIENTDSSSLLTIP--QVTRND 20841 Query: 195 PGEYECNATNAIGSASVVTV 214 G+Y N +G TV Sbjct: 20842 TGKYILTIENGVGEPKSSTV 20861 Score = 30.8 bits (68), Expect = 1.4 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 5/99 (5%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP I +S+ +G DA + VG P P+ W K NG+ ++ + ++ ++N Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK--NGVKIE--RSDRIYWYWPEDN 2086 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 EL ++ ED A N G S L V++ Sbjct: 2087 VCEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2124 Score = 30.8 bits (68), Expect = 1.4 Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 16/162 (9%) Query: 60 SHTLTYSYWTKNGVELSATRKNASNMEYRINK-----PRAEDSGEYHCVYHFVSAPKANA 114 SH S W KNGVE+ + K ++ ++++ EDS EY V + +A Sbjct: 2860 SHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV---CGNDQVSA 2916 Query: 115 TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFF 174 T+ V P + + E +D + +V Y + W K NG+ + ++ + Sbjct: 2917 TLTV--TPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLK--NGVE---IKSTDKCQ 2969 Query: 175 IINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 216 + K+ LNI N+ D +Y A A +A++ R Sbjct: 2970 MRTKKLTHSLNIRNVHF-GDAADYTFVAGKATSTATLYVEAR 3010 Score = 30.8 bits (68), Expect = 1.4 Identities = 42/179 (23%), Positives = 66/179 (36%), Gaps = 38/179 (21%) Query: 51 TLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYH--------- 101 TL C +T H W + G E+ A ++YRI E G YH Sbjct: 24449 TLVCKVTG--HPKPIVKWYRQGKEIIA-----DGLKYRIQ----EFKGGYHQLIIASVTD 24497 Query: 102 ---CVYHFVSAPKAN-----ATIEVKAAPDITGHKRSENKN-----EGQDATMYCKSVGY 148 VY + + A++EV+ I K E G+ ++ G Sbjct: 24498 DDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGK 24557 Query: 149 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207 P P W+K + D+++ +G + +I ++T L N +D G Y A N G Sbjct: 24558 PDPVITWQKGQ-----DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 24611 Score = 30.8 bits (68), Expect = 1.4 Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 8/110 (7%) Query: 110 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 169 PKA I K P I + + A K+ G P P IW K + T Sbjct: 26345 PKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAI------T 26396 Query: 170 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 G + ++++ ++ T D G Y C N+ GS S L +++ Sbjct: 26397 QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 26446 Score = 30.4 bits (67), Expect = 1.8 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 7/62 (11%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G P P +W K+E + D R I N +EL I+ + +D G Y ATN+ Sbjct: 8633 GRPVPTKVWTKEEGELDKD------RVVIDNVGTKSEL-IIKDALRKDHGRYVITATNSC 8685 Query: 207 GS 208 GS Sbjct: 8686 GS 8687 Score = 29.6 bits (65), Expect = 3.1 Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 6/99 (6%) Query: 120 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 179 A P+ +S +G + + G P P + + +G + S F I++E Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQ----SSLDFQISQE 155 Query: 180 NYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 218 ++ ED G Y NATN++G A+ L V+ Sbjct: 156 GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 29.3 bits (64), Expect = 4.1 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 EG T +CK GYP P W K +G + F+ + + +V + ED Sbjct: 1258 EGMGVTFHCKMSGYPLPKIAWYK--DGKRIKHGERYQMDFLQDGRASLRIPVV---LPED 1312 Query: 195 PGEYECNATNAIGSA 209 G Y A+N G+A Sbjct: 1313 EGIYTAFASNIKGNA 1327 Score = 29.3 bits (64), Expect = 4.1 Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G P P W + + D + + +N++ + + + D GEY+ +NA Sbjct: 11039 GVPVPTAKWTTDGSEIKTD------EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 11092 Query: 207 GSASVVTVLRV 217 GS +V L V Sbjct: 11093 GSKTVAVHLTV 11103 Score = 28.9 bits (63), Expect = 5.3 Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 147 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 206 G PHP W+K E+ ++V +S ++K + + + I+ +D G Y A N+ Sbjct: 12427 GKPHPTCKWKKGED----EVVTSS--HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSS 12480 Query: 207 GS 208 G+ Sbjct: 12481 GT 12482 Score = 28.5 bits (62), Expect = 6.9 Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 4/103 (3%) Query: 121 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 180 AP T +S EG AT G+P P+ W + +G + G I + Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFR--DGQVISTSTLPG-VQISFSDG 61 Query: 181 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 223 +L I + + G Y ATN G A+ L V++ AP Sbjct: 62 RAKLTIPAVT-KANSGRYSLKATNGSGQATSTAELLVKAETAP 103 Score = 28.1 bits (61), Expect = 9.0 Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 6/71 (8%) Query: 96 DSGEYHCVYH------FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 149 DSGE+ V +S +E + P ++ N EG M ++ G P Sbjct: 1478 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1537 Query: 150 HPDWIWRKKEN 160 +PD +W K + Sbjct: 1538 NPDIVWLKNSD 1548 Score = 28.1 bits (61), Expect = 9.0 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 147 GYPHPDWIWRKKENGM--PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 G P P W K E + P D + + + + E TEL+I + ED G Y A+N Sbjct: 8927 GLPMPKIEWSKNETVIEKPTDALQIT-KEEVSRSEAKTELSIPKA-VREDKGTYTVTASN 8984 Query: 205 AIGS 208 +GS Sbjct: 8985 RLGS 8988 >gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sapiens] Length = 858 Score = 53.1 bits (126), Expect = 3e-07 Identities = 59/247 (23%), Positives = 96/247 (38%), Gaps = 40/247 (16%) Query: 10 LALSLLLVSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVL---PVTLQC--NLTSSSHTLT 64 L+ + L + G G + E RI+ E+ +D V+ P T+Q N+ +++ L Sbjct: 169 LSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLG 228 Query: 65 YSY---------------WTKNGVELSATRKNAS------NMEYRINKPRAEDSGEYHCV 103 S WTK+G ++ + + + I K D EY C+ Sbjct: 229 QSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICI 288 Query: 104 YHFVSAPKANATIEVK--AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161 A + +ATI +K A P IT + + T+ C++ G P P WR Sbjct: 289 AEN-KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRN 347 Query: 162 M----------PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASV 211 + P G + + + L + ++Q T D GEY C A+N IG S Sbjct: 348 ISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYT-DAGEYICTASNTIGQDSQ 406 Query: 212 VTVLRVR 218 L V+ Sbjct: 407 SMYLEVQ 413 Score = 43.9 bits (102), Expect = 2e-04 Identities = 35/156 (22%), Positives = 61/156 (39%), Gaps = 16/156 (10%) Query: 54 CNLTSSSHTLTYSYWTKNGVELSATRKNAS-------NMEYRINKPRAEDSGEYHCVYHF 106 C + + S+++ NG +L+ ++ S + I +D+G Y CV Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTG 100 Query: 107 VSAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 164 ++ AT+ VK + + EG+DA + C V P IW+ K Sbjct: 101 EDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGR---- 156 Query: 165 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200 D++ FI+ NY ++ + D G Y C Sbjct: 157 DVILKKDVRFIVLSNNYLQIRGIK---KTDEGTYRC 189 Score = 37.7 bits (86), Expect = 0.011 Identities = 33/131 (25%), Positives = 50/131 (38%), Gaps = 26/131 (19%) Query: 96 DSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154 D+GEY C + + + +EV+ AP + G EG + C+ YP Sbjct: 389 DAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSATIS 447 Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVN------LQITEDP----GEYECNATN 204 W + +P NY+ + I N L++T D G Y C A N Sbjct: 448 WFRDGQLLP--------------SSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVN 493 Query: 205 AIGSASVVTVL 215 IG S+ +L Sbjct: 494 RIGQESLEFIL 504 >gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] Length = 3874 Score = 52.4 bits (124), Expect = 4e-07 Identities = 46/160 (28%), Positives = 70/160 (43%), Gaps = 17/160 (10%) Query: 68 WTKNGVELSA--TRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDI 124 W K G+ ++ + + + RI ED+G Y C+ + + + V+ P I Sbjct: 2790 WQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVI 2849 Query: 125 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 184 + EG A + CK+ G P P+ W K +G P + G+F I + EL Sbjct: 2850 ENGLPDLSTTEGSHAFLPCKARGSPEPNITWDK--DGQP--VSGAEGKFTI---QPSGEL 2902 Query: 185 NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPL 224 + NL+ +D G Y C A NA+G A R R HL L Sbjct: 2903 LVKNLE-GQDAGTYTCTAENAVGRA------RRRVHLTIL 2935 Score = 50.1 bits (118), Expect = 2e-06 Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 12/162 (7%) Query: 67 YWTKNGVEL--SATRKNASNMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPD 123 +W K+G+ L S R N I++ +D+G Y C+ + + K + +++AP Sbjct: 3060 HWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPV 3119 Query: 124 ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTE 183 + G D + C++ G P P W + G P+ S R + + Sbjct: 3120 FQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQA--GQPL---RASRRLRTLPDGSLWL 3174 Query: 184 LNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLW 225 N+ T D G Y+C A N +GSA+ L VR W Sbjct: 3175 ENVE----TGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSW 3212 Score = 44.3 bits (103), Expect = 1e-04 Identities = 60/220 (27%), Positives = 87/220 (39%), Gaps = 25/220 (11%) Query: 17 VSGSLLPGPGAAQNEPRIVTSEEVIIRDSPVL---PVTLQCNLTSS-SHTLTYSYWTKNG 72 V+GS G N P +T + PVL PV L CN T + S TL W K+G Sbjct: 770 VAGSTELRYGLRVNVPPRITLPPSL--PGPVLVNTPVRLTCNATGAPSPTLM---WLKDG 824 Query: 73 VELSATRKNASNM-----EYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITG 126 +S + + RA DSG Y CV V + + ++V P I G Sbjct: 825 NPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILG 884 Query: 127 HKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNI 186 + + + + + C+S P P W K +G P++ G +K L Sbjct: 885 EELNVSVVANESVALECQSHAMPPPVLSWWK--DGRPLE--PRPGVHLSADK----ALLQ 936 Query: 187 VNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWP 226 V+ D G Y C A N G + L V +AP++P Sbjct: 937 VDRADVWDAGHYTCEALNQAGRSEKHYNLNV--WVAPVFP 974 Score = 44.3 bits (103), Expect = 1e-04 Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 9/123 (7%) Query: 96 DSGEYHCVYHFVSAPKANA-TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 154 DSG+Y C + + A +E+ P I + N + Q A + C++ G P P Sbjct: 2455 DSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVS 2514 Query: 155 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTV 214 WRK + +P+D S RF I+ + + + + +D G Y C A+N+ GS Sbjct: 2515 WRK--DRVPLD--PRSPRFEILPEGSLR----IQPVLAQDAGHYLCLASNSAGSDRQGRD 2566 Query: 215 LRV 217 LRV Sbjct: 2567 LRV 2569 Score = 42.0 bits (97), Expect = 6e-04 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 11/133 (8%) Query: 88 RINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAAPDITGHKRSENKNEGQD--ATMYCK 144 RI D G Y CV + +A + + V A P I G + +D + C+ Sbjct: 275 RITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCE 334 Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 + G P P+ W K +P TS + ++ +L + Q + D G Y C A+N Sbjct: 335 ARGVPTPNITWFKDGALLP-----TSTK--VVYTRGGRQLQLGRAQ-SSDAGVYTCKASN 386 Query: 205 AIGSASVVTVLRV 217 A+G+A T L V Sbjct: 387 AVGAAEKATRLDV 399 Score = 42.0 bits (97), Expect = 6e-04 Identities = 41/167 (24%), Positives = 66/167 (39%), Gaps = 19/167 (11%) Query: 52 LQCNLTSSSHTLTYSYWTKNGVELS---ATRKNASNMEYRINKPRAEDSGEYHCVY-HFV 107 L CN+T H W K+G L+ A + + ++ + +G Y C+ + V Sbjct: 1274 LMCNVTG--HPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAV 1331 Query: 108 SAPKANATIEVKAAPDITGHKRSENKNE-----GQDATMYCKSVGYPHPDWIWRKKENGM 162 + + V AP I G E ++ C+++ +P P+ W K +G Sbjct: 1332 GEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK--DGA 1389 Query: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 209 P + I L I+N Q ED G+Y C TN +G A Sbjct: 1390 PFEASRN-----IQLLPGTHGLQILNAQ-KEDAGQYTCVVTNELGEA 1430 Score = 41.6 bits (96), Expect = 8e-04 Identities = 46/184 (25%), Positives = 74/184 (40%), Gaps = 22/184 (11%) Query: 49 PVTLQCNLTSSSHTLTYSYWTKNGV---ELSATRKNASNMEYRINKPRAEDSGEYHCVYH 105 PV L+C + H W G+ E + +R R+ P SG Y CV Sbjct: 422 PVALEC--VARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCV-- 477 Query: 106 FVSAPKANA----TIEVKAAPDITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKE 159 S+P A ++EV+ P + + GQ + C++ G P P W + Sbjct: 478 -ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL--Q 534 Query: 160 NGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 NG P + +G + T L+I ++++ + G + C ATN G+A + V Sbjct: 535 NGRPAE--ELAG---VQVASQGTTLHIDHVEL-DHSGLFACQATNEAGTAGAEVEVSVHG 588 Query: 220 HLAP 223 AP Sbjct: 589 EWAP 592 Score = 40.4 bits (93), Expect = 0.002 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 11/123 (8%) Query: 88 RINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSE--NKNEGQDATMYCK 144 ++ + + +DSG Y C+ + + N ++EV P I E +GQ A + C Sbjct: 1218 KMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCN 1277 Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 G+P P W K +G P+ G I+ + L ++ ++ G Y C A N Sbjct: 1278 VTGHPQPKLTWFK--DGRPL----ARGDAHHISPDGVL-LQVLQANLS-SAGHYSCIAAN 1329 Query: 205 AIG 207 A+G Sbjct: 1330 AVG 1332 Score = 40.0 bits (92), Expect = 0.002 Identities = 45/166 (27%), Positives = 75/166 (45%), Gaps = 16/166 (9%) Query: 49 PVTLQCNLTS-SSHTLTYSYWTKNG--VELSATRKNASNM-EYRINKPRAEDSGEYHCVY 104 P+ L C+++ + T+T W K+ VE SA S ++++ + +G Y CV Sbjct: 1950 PLVLTCDVSGVPAPTVT---WLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 2006 Query: 105 HFVSAP-KANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 161 A + + + V AP I +G R + EGQ+ + C++ G P PD W K + Sbjct: 2007 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSP 2066 Query: 162 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207 + D + RF++ + L + L+ D G Y C A N G Sbjct: 2067 LGQD-MGPHLRFYL----DGGSLVLKGLR-ASDAGAYTCVAHNPAG 2106 Score = 39.7 bits (91), Expect = 0.003 Identities = 45/184 (24%), Positives = 73/184 (39%), Gaps = 23/184 (12%) Query: 45 SPVLPVTLQCNLTSSSH-TLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCV 103 +P P+ L C+ + +T W K+G L+ N+ R D+G Y C+ Sbjct: 2317 TPGAPMELLCDAQGTPQPNIT---WHKDGQALTRLENNSRATRVL----RVRDAGLYTCL 2369 Query: 104 YHF-VSAPKANATIEVKAAPDITGHKRSE---NKNEGQDATMYCKSVGYPHPDWIWRKKE 159 A + + + V+A P+I G + GQ + C P P W + Sbjct: 2370 AESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQ-LVLECSVEAEPAPKITWHR-- 2426 Query: 160 NGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 219 +G+ ++ + + +L ++ T D G+Y C A NA GS SV RV Sbjct: 2427 DGI---VLQEDAHTQFPERGRFLQLQALS---TADSGDYSCTARNAAGSTSV--AFRVEI 2478 Query: 220 HLAP 223 H P Sbjct: 2479 HTVP 2482 Score = 38.5 bits (88), Expect = 0.007 Identities = 36/134 (26%), Positives = 52/134 (38%), Gaps = 15/134 (11%) Query: 88 RINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 146 +I K D G Y C + K ++V P+I ++ E T+ C + Sbjct: 660 QIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLAS 719 Query: 147 GYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 203 G P PD W K + + V+ GR L I Q++ D G Y C A+ Sbjct: 720 GVPPPDVSWFKGHQPVSSWMGVTVSVDGRV----------LRIEQAQLS-DAGSYRCVAS 768 Query: 204 NAIGSASVVTVLRV 217 N GS + LRV Sbjct: 769 NVAGSTELRYGLRV 782 Score = 37.4 bits (85), Expect = 0.015 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 96 DSGEYHC-VYHFVSAPKANATIEVKAAPDIT--GHKRSENKNEGQDATMYCKSVGYPHPD 152 DSG+Y C + V + A + V P I G K + + GQ T+ C + G+P P+ Sbjct: 68 DSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPE 127 Query: 153 WIWRKKEN--GMPM 164 +W K G+P+ Sbjct: 128 IVWLKDAQLVGVPL 141 Score = 36.2 bits (82), Expect = 0.033 Identities = 42/204 (20%), Positives = 75/204 (36%), Gaps = 29/204 (14%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSY--WTKNGVELS---ATRKNASNME 86 P + EE+ + V L+C SH + W K+G L +A Sbjct: 879 PPSILGEELNVSVVANESVALECQ----SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL 934 Query: 87 YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDIT-GHKRSENKNEGQDATMYCK 144 ++++ D+G Y C + + + + V AP + EG ++ C+ Sbjct: 935 LQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCE 994 Query: 145 SVGYPHPDWIWRKKENGMP-----MDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYE 199 G P P WRK +P + V+ GR + + + G Y Sbjct: 995 CRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQ-----------EGTYT 1043 Query: 200 CNATNAIGSASVVTVLRVRSHLAP 223 C +N +G++S L++ H+ P Sbjct: 1044 CECSNVVGNSS--QDLQLEVHVPP 1065 Score = 35.4 bits (80), Expect = 0.057 Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 13/131 (9%) Query: 93 RAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRS----ENKNEGQDATMYCKSVG 147 RAE++G Y C + V + + V P I G N ++ C ++G Sbjct: 1621 RAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALG 1680 Query: 148 YPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 207 P P W +NG+P + S R ++ +++ + D Y C A N G Sbjct: 1681 NPVPTISWL--QNGLPF---SPSPRLQVLEDGQVLQVSTAEVA---DAASYMCVAENQAG 1732 Query: 208 SASVVTVLRVR 218 SA + LRV+ Sbjct: 1733 SAEKLFTLRVQ 1743 Score = 34.7 bits (78), Expect = 0.097 Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 17/73 (23%) Query: 143 CKSVGYPHPDWIWRKKEN-----GMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE 197 C + G P P WRK + G P V G F+ + D G+ Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVS------------PADSGD 71 Query: 198 YECNATNAIGSAS 210 YEC ATN +GS S Sbjct: 72 YECQATNEVGSTS 84 Score = 34.3 bits (77), Expect = 0.13 Identities = 43/200 (21%), Positives = 77/200 (38%), Gaps = 33/200 (16%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90 P + ++ + + PV L C+ T + T++ W+K G +L A YR++ Sbjct: 2665 PPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS---WSKAGAQLGARGSG-----YRVS 2716 Query: 91 KPRAED--------SGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATM 141 A + +G Y C + + + V+A+P + ++ + Sbjct: 2717 PSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLL 2776 Query: 142 YCKSVGYPHPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEY 198 C++ G P P W+K+ + + V G+ I + ED G Y Sbjct: 2777 PCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHAS------------PEDAGNY 2824 Query: 199 ECNATNAIGSASVVTVLRVR 218 C A N+ GSA T L V+ Sbjct: 2825 LCIAKNSAGSAMGKTRLVVQ 2844 Score = 33.5 bits (75), Expect = 0.22 Identities = 39/185 (21%), Positives = 70/185 (37%), Gaps = 17/185 (9%) Query: 38 EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA---SNMEYRINKPRA 94 EEV + S V+LQC + + + W +NG+ S + + +++ Sbjct: 1662 EEVTVNASST--VSLQC--PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 1717 Query: 95 EDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSE-NKNEGQDATMYCKSVGYPHPD 152 D+ Y CV + + + T+ V+ P I G + ++ C +P+P+ Sbjct: 1718 ADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPE 1777 Query: 153 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 212 W K + + F++ + +L L D G Y C A NA G + Sbjct: 1778 VTWYKDSQALSL-----GEEVFLLPGTHTLQLGRARLS---DSGMYTCEALNAAGRDQKL 1829 Query: 213 TVLRV 217 L V Sbjct: 1830 VQLSV 1834 Score = 32.0 bits (71), Expect = 0.63 Identities = 42/189 (22%), Positives = 73/189 (38%), Gaps = 28/189 (14%) Query: 32 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSH-TLTYSYWTKNG----VELSATRKNASNME 86 PR ++ +++D TL+CN T T+T W ++G EL +N Sbjct: 1070 PREPPTQVSVVQDGVA---TLECNATGKPPPTVT---WERDGQPVGAELGLQLQN-QGQS 1122 Query: 87 YRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEG---QDATMY 142 + + +A +G Y CV + + + V P++ G T+ Sbjct: 1123 LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLL 1182 Query: 143 CKSVGYPHPDWIWRKKENGMPM--DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200 C+++G P P W + E + D +G + + K T+ +D G Y C Sbjct: 1183 CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWML--KMTQTQ--------EQDSGLYSC 1232 Query: 201 NATNAIGSA 209 A+N G A Sbjct: 1233 LASNEAGEA 1241 Score = 31.2 bits (69), Expect = 1.1 Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 135 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 194 E A +YC + P PD W +++ + + ++ ++ +V E+ Sbjct: 1573 ENNPAYLYCDTNAIPPPDLTWYREDQPL-----SAGDEVSVLQGGRVLQIPLVR---AEN 1624 Query: 195 PGEYECNATNAIG 207 G Y C A+N +G Sbjct: 1625 AGRYSCKASNEVG 1637 Score = 30.0 bits (66), Expect = 2.4 Identities = 30/125 (24%), Positives = 47/125 (37%), Gaps = 12/125 (9%) Query: 89 INKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENK-NEGQD--ATMYCK 144 + + + G Y C + V + +EV P I G + + + QD AT+ C Sbjct: 1031 LGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECN 1090 Query: 145 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 204 + G P P W + +G P+ G + +N + V G Y C A N Sbjct: 1091 ATGKPPPTVTWER--DGQPV------GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN 1142 Query: 205 AIGSA 209 G A Sbjct: 1143 LAGRA 1147 Score = 29.3 bits (64), Expect = 4.1 Identities = 43/205 (20%), Positives = 74/205 (36%), Gaps = 25/205 (12%) Query: 26 GAAQNEPRIVTSEEVIIRDS-PVLPVT------LQCNLTSSSH-TLTYSYWTKNGVELSA 77 G+A + R+V +I + P L T L C S +T W K+G +S Sbjct: 2833 GSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNIT---WDKDGQPVSG 2889 Query: 78 TRKNAS---NMEYRINKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENK 133 + + E + +D+G Y C + V + + + P T + Sbjct: 2890 AEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSL 2949 Query: 134 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 193 G + C + G P P W + + T G + ++ + L + E Sbjct: 2950 RLGDRLWLRCAARGSPTPRIGWTVNDRPV------TEG---VSEQDGGSTLQRAAVS-RE 2999 Query: 194 DPGEYECNATNAIGSASVVTVLRVR 218 D G Y C A N +G V+ + V+ Sbjct: 3000 DSGTYVCWAENRVGRTQAVSFVHVK 3024 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.130 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,484,061 Number of Sequences: 37866 Number of extensions: 512718 Number of successful extensions: 2474 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 107 Number of HSP's successfully gapped in prelim test: 219 Number of HSP's that attempted gapping in prelim test: 1275 Number of HSP's gapped (non-prelim): 1003 length of query: 282 length of database: 18,247,518 effective HSP length: 101 effective length of query: 181 effective length of database: 14,423,052 effective search space: 2610572412 effective search space used: 2610572412 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.