Guide to the Human Genome
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Search of human proteins with 91984781

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|91984781 ArfGAP with FG repeats 2 [Homo sapiens]
         (481 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|91984781 ArfGAP with FG repeats 2 [Homo sapiens]                   981   0.0  
gi|206597509 HIV-1 Rev binding protein isoform 4 [Homo sapiens]       297   2e-80
gi|38570132 HIV-1 Rev binding protein isoform 2 [Homo sapiens]        294   1e-79
gi|206597507 HIV-1 Rev binding protein isoform 3 [Homo sapiens]       290   2e-78
gi|206597505 HIV-1 Rev binding protein isoform 1 [Homo sapiens]       271   1e-72
gi|21264558 stromal membrane-associated GTPase-activating protei...    74   4e-13
gi|23943872 small ArfGAP2 [Homo sapiens]                               70   3e-12
gi|113204622 stromal membrane-associated GTPase-activating prote...    70   4e-12
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          65   1e-10
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          65   1e-10
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          65   1e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni...    61   2e-09
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ...    60   3e-09
gi|23510333 pygopus homolog 2 [Homo sapiens]                           59   7e-09
gi|6806913 centaurin, alpha 1 [Homo sapiens]                           59   1e-08
gi|38373671 SEC24-related protein C [Homo sapiens]                     59   1e-08
gi|38373669 SEC24-related protein C [Homo sapiens]                     59   1e-08
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         59   1e-08
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]                58   2e-08
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]                58   2e-08
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    57   3e-08
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do...    56   8e-08
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...    55   1e-07
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do...    55   2e-07
gi|7661880 centaurin beta1 [Homo sapiens]                              55   2e-07
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]     54   2e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    54   3e-07
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          54   4e-07
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...    54   4e-07
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...    54   4e-07

>gi|91984781 ArfGAP with FG repeats 2 [Homo sapiens]
          Length = 481

 Score =  981 bits (2537), Expect = 0.0
 Identities = 481/481 (100%), Positives = 481/481 (100%)

Query: 1   MVMAAKKGPGPGGGVSGGKAEAEAASEVWCRRVRELGGCSQAGNRHCFECAQRGVTYVDI 60
           MVMAAKKGPGPGGGVSGGKAEAEAASEVWCRRVRELGGCSQAGNRHCFECAQRGVTYVDI
Sbjct: 1   MVMAAKKGPGPGGGVSGGKAEAEAASEVWCRRVRELGGCSQAGNRHCFECAQRGVTYVDI 60

Query: 61  TVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVVFLQSRGNEVCRKIWLGLFDARTS 120
           TVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVVFLQSRGNEVCRKIWLGLFDARTS
Sbjct: 61  TVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVVFLQSRGNEVCRKIWLGLFDARTS 120

Query: 121 LVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGSASTPVQGSIPEGKPLRTLLG 180
           LVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGSASTPVQGSIPEGKPLRTLLG
Sbjct: 121 LVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGSASTPVQGSIPEGKPLRTLLG 180

Query: 181 DPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMA 240
           DPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMA
Sbjct: 181 DPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMA 240

Query: 241 PAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPF 300
           PAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPF
Sbjct: 241 PAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPF 300

Query: 301 GATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLA 360
           GATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLA
Sbjct: 301 GATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLA 360

Query: 361 FGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAP 420
           FGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAP
Sbjct: 361 FGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAP 420

Query: 421 LFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPPTTNPF 480
           LFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPPTTNPF
Sbjct: 421 LFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPPTTNPF 480

Query: 481 L 481
           L
Sbjct: 481 L 481


>gi|206597509 HIV-1 Rev binding protein isoform 4 [Homo sapiens]
          Length = 522

 Score =  297 bits (760), Expect = 2e-80
 Identities = 212/510 (41%), Positives = 250/510 (49%), Gaps = 85/510 (16%)

Query: 44  NRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVVFLQSRG 103
           NR CF+C QRG TYV++TVGSFVCT+CSG LRGLNPPHRVKSISMTTFT+ E+ FLQ  G
Sbjct: 26  NRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHG 85

Query: 104 NEVCRKIWLGLFDARTSLVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGS--- 160
           NEVC++IWLGLFD R+S +PD RDPQKVKEFLQEKYEKKRWYVPP+Q K       S   
Sbjct: 86  NEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISG 145

Query: 161 ASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKK 220
           +S     S PE KPL++LLGD AP+L +   T SQ      ++  Q            +K
Sbjct: 146 SSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQ-----------EK 194

Query: 221 ASTDLLADIGGDPFAAP-QMAPAFAAFPAF-------GGQTPS-QGGFANFDAFSSGPSS 271
              DLL+D+G D FAAP   + A A F  F       GG   S    FA+FD F    SS
Sbjct: 195 KQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAGGSAASVNANFAHFDNFPKS-SS 253

Query: 272 SVFG--------------SLPPAGQASFQAQPTPA-------------GSSQGTPFGATP 304
           + FG              S     +A  Q     A             G  QG+ FG T 
Sbjct: 254 ADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTG 313

Query: 305 LAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMA------------------GQVPPLQS 346
            AP     S+    S       A     S+F  A                  G VP + S
Sbjct: 314 KAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVAS 373

Query: 347 VTMGGGGGSSTGLAFGA--FTNPFTAPAAQSPLPSTNPFQPNGL-APGPGFGMSS----A 399
                   SS    FGA   TNPF A A  S   STNPFQ N   A    FG +S     
Sbjct: 374 -AQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPT 432

Query: 400 GPGFPQAVPPTGAFASSFPAP------LFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQ- 452
           G G P       +F+ SF  P       FP QT   QQ NG+ F   G  K    P  Q 
Sbjct: 433 GFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQV 492

Query: 453 -PAGISTNPFMTGPSSSPFASKPPTTNPFL 481
             AG+S+NPFMTG  +  F +   +TNPFL
Sbjct: 493 AAAGVSSNPFMTGAPTGQFPTGSSSTNPFL 522


>gi|38570132 HIV-1 Rev binding protein isoform 2 [Homo sapiens]
          Length = 562

 Score =  294 bits (753), Expect = 1e-79
 Identities = 212/549 (38%), Positives = 255/549 (46%), Gaps = 123/549 (22%)

Query: 44  NRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVVFLQSRG 103
           NR CF+C QRG TYV++TVGSFVCT+CSG LRGLNPPHRVKSISMTTFT+ E+ FLQ  G
Sbjct: 26  NRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHG 85

Query: 104 NEVCRKIWLGLFDARTSLVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGS--- 160
           NEVC++IWLGLFD R+S +PD RDPQKVKEFLQEKYEKKRWYVPP+Q K       S   
Sbjct: 86  NEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISG 145

Query: 161 ASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKK 220
           +S     S PE KPL++LLGD AP+L +   T SQ      ++  Q            +K
Sbjct: 146 SSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQ-----------EK 194

Query: 221 ASTDLLADIGGDPFAAPQMAPA-------FAAFPAFGGQTPSQGGFANFDAF-------- 265
              DLL+D+G D FAAP            FA F +   Q  +   FANFDAF        
Sbjct: 195 KQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSN 254

Query: 266 ----------------SSGPSSSV------FGSLPPAGQASF------QAQPTPA----- 292
                           + G ++SV      F + P +  A F      Q+  T +     
Sbjct: 255 FGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKV 314

Query: 293 ---------------------------GSSQGTPFGATPLAPASQPNSLADVGSFLGPGV 325
                                      G  QG+ FG T  AP     S+    S      
Sbjct: 315 STNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKY 374

Query: 326 PAAGVPSSLFGMA------------------GQVPPLQSVTMGGGGGSSTGLAFGAF--T 365
            A     S+F  A                  G VP + S        SS    FGA   T
Sbjct: 375 AALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS-SSVPAPFGATPST 433

Query: 366 NPFTAPAAQSPLPSTNPFQPNGL-APGPGFGMSS----AGPGFPQAVPPTGAFASSFPAP 420
           NPF A A  S   STNPFQ N   A    FG +S     G G P       +F+ SF  P
Sbjct: 434 NPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQP 493

Query: 421 LFPPQ------TPLVQQQNGSSFGDLGSAKLGQRPLSQ--PAGISTNPFMTGPSSSPFAS 472
            FP Q      T   QQ NG+ F   G  K    P  Q   AG+S+NPFMTG  +  F +
Sbjct: 494 AFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPT 553

Query: 473 KPPTTNPFL 481
              +TNPFL
Sbjct: 554 GSSSTNPFL 562


>gi|206597507 HIV-1 Rev binding protein isoform 3 [Homo sapiens]
          Length = 560

 Score =  290 bits (742), Expect = 2e-78
 Identities = 210/547 (38%), Positives = 253/547 (46%), Gaps = 121/547 (22%)

Query: 44  NRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVVFLQSRG 103
           NR CF+C QRG TYV++TVGSFVCT+CSG LRGLNPPHRVKSISMTTFT+ E+ FLQ  G
Sbjct: 26  NRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHG 85

Query: 104 NEVCRKIWLGLFDARTSLVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGS--- 160
           NEVC++IWLGLFD R+S +PD RDPQKVKEFLQEKYEKKRWYVPP+Q K       S   
Sbjct: 86  NEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISG 145

Query: 161 ASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKK 220
           +S     S PE KPL++LLGD AP+L +   T SQ      ++  Q            +K
Sbjct: 146 SSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQ-----------EK 194

Query: 221 ASTDLLADIGGDPFAAPQMAPA-------FAAFPAFGGQTPSQGGFANFDAF-------- 265
              DLL+D+G D FAAP            FA F +   Q  +   FANFDAF        
Sbjct: 195 KQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSN 254

Query: 266 ----------------SSGPSSSV------FGSLPPAGQASF------QAQPTPA----- 292
                           + G ++SV      F + P +  A F      Q+  T +     
Sbjct: 255 FGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKV 314

Query: 293 ---------------------------GSSQGTPFGATPLAPASQPNSLADVGSFLGPGV 325
                                      G  QG+ FG T  AP     S+    S      
Sbjct: 315 STNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKY 374

Query: 326 PAAGVPSSLFGMA------------------GQVPPLQSVTMGGGGGSSTGLAFGAF--T 365
            A     S+F  A                  G VP + S        SS    FGA   T
Sbjct: 375 AALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS-SSVPAPFGATPST 433

Query: 366 NPFTAPAAQSPLPSTNPFQPNGL-APGPGFGMSS----AGPGFPQAVPPTGAFASSFPAP 420
           NPF A A  S   STNPFQ N   A    FG +S     G G P       +F+ SF  P
Sbjct: 434 NPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQP 493

Query: 421 LFPPQTPLVQQ----QNGSSFGDLGSAKLGQRPLSQ--PAGISTNPFMTGPSSSPFASKP 474
            FP Q    QQ    Q  + F   G  K    P  Q   AG+S+NPFMTG  +  F +  
Sbjct: 494 AFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGS 553

Query: 475 PTTNPFL 481
            +TNPFL
Sbjct: 554 SSTNPFL 560


>gi|206597505 HIV-1 Rev binding protein isoform 1 [Homo sapiens]
          Length = 584

 Score =  271 bits (693), Expect = 1e-72
 Identities = 209/561 (37%), Positives = 252/561 (44%), Gaps = 125/561 (22%)

Query: 44  NRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVVFLQSRG 103
           NR CF+C QRG TYV++TVGSFVCT+CSG LRGLNPPHRVKSISMTTFT+ E+ FLQ  G
Sbjct: 26  NRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHG 85

Query: 104 NEVCRKIWLGLFDARTSLVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGS--- 160
           NEVC++IWLGLFD R+S +PD RDPQKVKEFLQEKYEKKRWYVPP+Q K       S   
Sbjct: 86  NEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISG 145

Query: 161 ASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQ------------------------- 195
           +S     S PE KPL++LLGD AP+L +   T SQ                         
Sbjct: 146 SSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQSPVVGRSQGQQQEKKQFDLLSDLGS 205

Query: 196 -----PVSQSHARTSQARSTQPPPHSSVKKASTDLL-----------ADIGGDPFAA--- 236
                P  QS A  + A       H++   A+ D             ++ GG P A+   
Sbjct: 206 DIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTASHSP 265

Query: 237 --PQ-----MAPAFAAFPAFGGQTPSQG-----------GFANFDAFSSGPSSSVFGSLP 278
             PQ     M  +  +F  F    P Q             FA+FD F    SS+ FG+  
Sbjct: 266 FQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKS-SSADFGTFN 324

Query: 279 PA--------------GQASFQAQPTPA-------------GSSQGTPFGATPLAPASQP 311
            +               +A  Q     A             G  QG+ FG T  AP    
Sbjct: 325 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV 384

Query: 312 NSLADVGSFLGPGVPAAGVPSSLFGMA------------------GQVPPLQSVTMGGGG 353
            S+    S       A     S+F  A                  G VP + S       
Sbjct: 385 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS 444

Query: 354 GSSTGLAFGAF--TNPFTAPAAQSPLPSTNPFQPNGL-APGPGFGMSS----AGPGFPQA 406
            SS    FGA   TNPF A A  S   STNPFQ N   A    FG +S     G G P  
Sbjct: 445 -SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAP 503

Query: 407 VPPTGAFASSFPAPLFPPQTPLVQQ----QNGSSFGDLGSAKLGQRPLSQ--PAGISTNP 460
                +F+ SF  P FP Q    QQ    Q  + F   G  K    P  Q   AG+S+NP
Sbjct: 504 YSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNP 563

Query: 461 FMTGPSSSPFASKPPTTNPFL 481
           FMTG  +  F +   +TNPFL
Sbjct: 564 FMTGAPTGQFPTGSSSTNPFL 584


>gi|21264558 stromal membrane-associated GTPase-activating protein 1
           isoform B [Homo sapiens]
          Length = 440

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 95/420 (22%), Positives = 155/420 (36%), Gaps = 68/420 (16%)

Query: 44  NRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPP-HRVKSISMTTFTEPEVVFLQSR 102
           N++C +C  +G  +    +G F+C  C+G+ R L     RVKS+++  +T  ++  +Q  
Sbjct: 30  NKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDM 89

Query: 103 GNEVCRKIWLGLFDARTSLVPDSRDP---QKVKEFLQEKYEKKRWYVPPDQVKGPTYTKG 159
           GN   R ++        +L  + R P   Q V+ F+++KYEKK++Y   + +      K 
Sbjct: 90  GNTKARLLY------EANLPENFRRPQTDQAVEFFIRDKYEKKKYY-DKNAIAITNKEKE 142

Query: 160 SASTPVQGSIPEGKPLRTLLGDP--------APSLSVAASTSSQPV-------SQSHART 204
                 +      KP + L  +          P  S +   +++P          + A  
Sbjct: 143 KKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPV 202

Query: 205 SQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQGGFANFDA 264
           +   +T PP +  +     D+   +  +P  A  M PA     A    T S     + D 
Sbjct: 203 TNGNTTVPPLNDDL-----DIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDL 257

Query: 265 FSSGPSS---------SVFGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAPASQPNSLA 315
           F+   +          S    L   G  + Q Q TP      T    T  APA+      
Sbjct: 258 FTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAA------ 311

Query: 316 DVGSFLGPGVPAAGVPSSLFGMAGQVPPLQ-SVTMGGG--GGSSTGL------------- 359
               F   GVP    P  +  + GQ P +   + M  G  G + TG+             
Sbjct: 312 -FQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGG 370

Query: 360 ---AFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASS 416
                GA  + F  P AQ P  S +  Q N    G     ++   GF Q    T  ++ S
Sbjct: 371 MVGQMGAPQSKFGLPQAQQPQWSLS--QMNQQMAGMSISSATPTAGFGQPSSTTAGWSGS 428


>gi|23943872 small ArfGAP2 [Homo sapiens]
          Length = 429

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 90/362 (24%), Positives = 147/362 (40%), Gaps = 70/362 (19%)

Query: 44  NRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPP-HRVKSISMTTFTEPEVVFLQSR 102
           N+ C +C  +G  +    +G F+C  C+G+ R L     RVKS+++  +T+ ++  +Q  
Sbjct: 25  NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEM 84

Query: 103 GNEVCRKIWLGLFDARTSLVPDS-RDPQ---KVKEFLQEKYEKKRWY------------- 145
           GN    +++        + +P++ R PQ    V+ F+++KYEKK++              
Sbjct: 85  GNGKANRLY-------EAYLPETFRRPQIDPAVEGFIRDKYEKKKYMDRSLDINAFRKEK 137

Query: 146 ----------VPP--------DQVKGPTYTKGSASTPVQGSIPEGKPLRTLLGDPAPSLS 187
                     VP         ++VK P   K     P + S     P+  LLG  AP   
Sbjct: 138 DDKWKRGSEPVPEKKLEPVVFEKVKMP-QKKEDPQLPRKSSPKSTAPVMDLLGLDAP--- 193

Query: 188 VAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAPAFAAFP 247
           VA S ++   S +  +     ++ P P SS  +     +   G    +A  +      FP
Sbjct: 194 VACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAG----SAGSVPENLNLFP 249

Query: 248 AFGGQTPSQGGFANFDAFSSGPSSSVFGSLPP--AGQASFQAQPTPAGSSQGTPFGATPL 305
             G ++   G        S     S++GS  P    QA F A   PA  +  T + + P 
Sbjct: 250 EPGSKSEEIGK----KQLSKDSILSLYGSQTPQMPTQAMFMA---PAQMAYPTAYPSFP- 301

Query: 306 APASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVT--MGGGGGSSTGLAFGA 363
              + PNS+  +GS + P V     P    G +G V P+      MGG   S  G+  G 
Sbjct: 302 -GVTPPNSI--MGSMMPPPVGMVAQP----GASGMVAPMAMPAGYMGGMQASMMGVPNGM 354

Query: 364 FT 365
            T
Sbjct: 355 MT 356


>gi|113204622 stromal membrane-associated GTPase-activating protein
           1 isoform A [Homo sapiens]
          Length = 467

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 96/430 (22%), Positives = 161/430 (37%), Gaps = 62/430 (14%)

Query: 44  NRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPP-HRVKSISMTTFTEPEVVFLQSR 102
           N++C +C  +G  +    +G F+C  C+G+ R L     RVKS+++  +T  ++  +Q  
Sbjct: 30  NKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDM 89

Query: 103 GNEVCRKIWLGLFDARTSLVPDSRDP---QKVKEFLQEKYEKKRWYVPPDQVKGPTYTKG 159
           GN   R ++        +L  + R P   Q V+ F+++KYEKK++Y              
Sbjct: 90  GNTKARLLY------EANLPENFRRPQTDQAVEFFIRDKYEKKKYY----------DKNA 133

Query: 160 SASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVK 219
            A T +  S     PL+ L+  P    S+ A+     + +   +  + +  +  P    K
Sbjct: 134 IAITNISSS---DAPLQPLVSSP----SLQAAVDKNKLEKEKEKKKEEKKREKEPEKPAK 186

Query: 220 KASTDLLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPP 279
             + + L             +P  AA P               D  +  P ++   ++PP
Sbjct: 187 PLTAEKLQKKDQQLEPKKSTSPKKAAEPTV--------DLLGLDGPAVAPVTNGNTTVPP 238

Query: 280 AGQ-----ASFQAQPTPA---GSSQGTPFGATPLAPASQPNSLADVGSFLGPGVPAAGVP 331
                       + P PA     +QGTP  + P A      +  D+  F      +  V 
Sbjct: 239 LNDDLDIFGPMISNPLPATVMPPAQGTP--SAPAAATLSTVTSGDLDLFTEQTTKSEEVA 296

Query: 332 SSLFGMAGQVPPLQSVTMGGGG----GSSTGLAFGAFTNPFT--APAAQSPLPSTNPFQP 385
                   Q+     +++ G G     S+ G+  G    PFT  APAA    PS     P
Sbjct: 297 KK------QLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMG--VP 348

Query: 386 NGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAPLFPPQTPLVQQQNGSSFGDLGS--A 443
              APG    +    P     +P    F  +    + P    +V  Q G   G +G+  +
Sbjct: 349 VPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQ-GGMVGQMGAPQS 407

Query: 444 KLGQRPLSQP 453
           K G     QP
Sbjct: 408 KFGLPQAQQP 417


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 91/361 (25%), Positives = 127/361 (35%), Gaps = 51/361 (14%)

Query: 120 SLVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGSASTPVQGSIPEGKPLRTLL 179
           S  P    PQ  +       +++     P  ++ PT       TP   S P G P    L
Sbjct: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT-----GVTPAPSSAPPGTPQ---L 207

Query: 180 GDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQM 239
             P P+ S  A       + S A       T P PH+ +++A           P   PQ 
Sbjct: 208 PTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA-----------PALHPQR 256

Query: 240 APAFAAFPAFGGQTPSQ--GGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQG 297
            P+    P      P Q   G A   +  S     + G  PP G  S QA P        
Sbjct: 257 PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP-GPHSLQAGPLLQHPGPP 315

Query: 298 TPFGATPLAPASQPNSLADVGSFLGPGVP--AAGVPSSLFGMAGQVPPLQSVTMGGGGGS 355
            PFG  P A   Q    A +G+      P  +  +P+S   +  Q PP +          
Sbjct: 316 QPFGLPPQASQGQ----APLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL------P 365

Query: 356 STGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFAS 415
              LA      P T P  Q P P  +   P+   P P F M++  P  P A+ P  + ++
Sbjct: 366 PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANLPP-PPALKPLSSLST 423

Query: 416 SFPAPLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPP 475
             P    PP   L+ Q          S  L   P +QP G++ +  +  P     AS PP
Sbjct: 424 HHPPSAHPPPLQLMPQ----------SQPLPSSP-AQPPGLTQSQNLPPPP----ASHPP 468

Query: 476 T 476
           T
Sbjct: 469 T 469



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 62/240 (25%), Positives = 78/240 (32%), Gaps = 61/240 (25%)

Query: 267 SGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPF----GATPLAPASQPNSLADVGSFLG 322
           S     +  + PPA QA     P P+ +  GTP     G TP A A  P           
Sbjct: 173 SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 232

Query: 323 -PGVPAAGVPSSLFGMAGQV-----------------PPLQSVTMGGGGGSSTGLAFGAF 364
            P  P A VP +    A  +                 PPLQ +T             G+ 
Sbjct: 233 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT-------------GSA 279

Query: 365 TNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTG----AFASSFPAP 420
             P     AQ PL    P  P+ L  GP   +   GP  P  +PP      A   + PA 
Sbjct: 280 GQPSAPSHAQPPLHGQGPPGPHSLQAGP--LLQHPGPPQPFGLPPQASQGQAPLGTSPAA 337

Query: 421 LFPP---QTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPPTT 477
            +P    Q P  Q           SA   Q+P  +       P    P + P    PPTT
Sbjct: 338 AYPHTSLQLPASQ-----------SALQSQQPPRE------QPLPPAPLAMPHIKPPPTT 380



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 79/306 (25%), Positives = 103/306 (33%), Gaps = 58/306 (18%)

Query: 182 PAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAP 241
           P P L     ++ QP + SHA+        P PHS   +A   L       PF  P  A 
Sbjct: 268 PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS--LQAGPLLQHPGPPQPFGLPPQAS 325

Query: 242 AFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFG 301
                    GQ P           ++ P +S+     PA Q++ Q+Q  P    +  P  
Sbjct: 326 Q--------GQAP-----LGTSPAAAYPHTSL---QLPASQSALQSQQPP----REQPLP 365

Query: 302 ATPLA-PASQPNSLADVGSFLGPGV----PAAGVPSSLFGMAGQVPPLQSVTMGGGGGSS 356
             PLA P  +P     +     P      P    PS  F M   +PP     +      S
Sbjct: 366 PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANLPP--PPALKPLSSLS 422

Query: 357 TGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTG----- 411
           T     A   P        PLPS +P QP      PG   S   P  P + PPTG     
Sbjct: 423 THHPPSAHPPPLQLMPQSQPLPS-SPAQP------PGLTQSQNLPPPPASHPPTGLHQVA 475

Query: 412 --------AFASSFPAPLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMT 463
                    F    P P+ PP  P       +S    G     Q P S  A  ++   + 
Sbjct: 476 PQPPFAQHPFVPGGPPPITPPTCP------STSTPPAGPGTSAQPPCSGAA--ASGGSIA 527

Query: 464 GPSSSP 469
           G SS P
Sbjct: 528 GGSSCP 533


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 91/361 (25%), Positives = 127/361 (35%), Gaps = 51/361 (14%)

Query: 120  SLVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGSASTPVQGSIPEGKPLRTLL 179
            S  P    PQ  +       +++     P  ++ PT       TP   S P G P    L
Sbjct: 710  STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT-----GVTPAPSSAPPGTPQ---L 761

Query: 180  GDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQM 239
              P P+ S  A       + S A       T P PH+ +++A           P   PQ 
Sbjct: 762  PTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA-----------PALHPQR 810

Query: 240  APAFAAFPAFGGQTPSQ--GGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQG 297
             P+    P      P Q   G A   +  S     + G  PP G  S QA P        
Sbjct: 811  PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP-GPHSLQAGPLLQHPGPP 869

Query: 298  TPFGATPLAPASQPNSLADVGSFLGPGVP--AAGVPSSLFGMAGQVPPLQSVTMGGGGGS 355
             PFG  P A   Q    A +G+      P  +  +P+S   +  Q PP +          
Sbjct: 870  QPFGLPPQASQGQ----APLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL------P 919

Query: 356  STGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFAS 415
               LA      P T P  Q P P  +   P+   P P F M++  P  P A+ P  + ++
Sbjct: 920  PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANLPP-PPALKPLSSLST 977

Query: 416  SFPAPLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPP 475
              P    PP   L+ Q          S  L   P +QP G++ +  +  P     AS PP
Sbjct: 978  HHPPSAHPPPLQLMPQ----------SQPLPSSP-AQPPGLTQSQNLPPPP----ASHPP 1022

Query: 476  T 476
            T
Sbjct: 1023 T 1023



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 62/240 (25%), Positives = 78/240 (32%), Gaps = 61/240 (25%)

Query: 267 SGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPF----GATPLAPASQPNSLADVGSFLG 322
           S     +  + PPA QA     P P+ +  GTP     G TP A A  P           
Sbjct: 727 SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 786

Query: 323 -PGVPAAGVPSSLFGMAGQV-----------------PPLQSVTMGGGGGSSTGLAFGAF 364
            P  P A VP +    A  +                 PPLQ +T             G+ 
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT-------------GSA 833

Query: 365 TNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTG----AFASSFPAP 420
             P     AQ PL    P  P+ L  GP   +   GP  P  +PP      A   + PA 
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGPHSLQAGP--LLQHPGPPQPFGLPPQASQGQAPLGTSPAA 891

Query: 421 LFPP---QTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPPTT 477
            +P    Q P  Q           SA   Q+P  +       P    P + P    PPTT
Sbjct: 892 AYPHTSLQLPASQ-----------SALQSQQPPRE------QPLPPAPLAMPHIKPPPTT 934



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 79/306 (25%), Positives = 103/306 (33%), Gaps = 58/306 (18%)

Query: 182  PAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAP 241
            P P L     ++ QP + SHA+        P PHS   +A   L       PF  P  A 
Sbjct: 822  PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS--LQAGPLLQHPGPPQPFGLPPQAS 879

Query: 242  AFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFG 301
                     GQ P           ++ P +S+     PA Q++ Q+Q  P    +  P  
Sbjct: 880  Q--------GQAP-----LGTSPAAAYPHTSL---QLPASQSALQSQQPP----REQPLP 919

Query: 302  ATPLA-PASQPNSLADVGSFLGPGV----PAAGVPSSLFGMAGQVPPLQSVTMGGGGGSS 356
              PLA P  +P     +     P      P    PS  F M   +PP     +      S
Sbjct: 920  PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANLPP--PPALKPLSSLS 976

Query: 357  TGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTG----- 411
            T     A   P        PLPS +P QP      PG   S   P  P + PPTG     
Sbjct: 977  THHPPSAHPPPLQLMPQSQPLPS-SPAQP------PGLTQSQNLPPPPASHPPTGLHQVA 1029

Query: 412  --------AFASSFPAPLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMT 463
                     F    P P+ PP  P       +S    G     Q P S  A  ++   + 
Sbjct: 1030 PQPPFAQHPFVPGGPPPITPPTCP------STSTPPAGPGTSAQPPCSGAA--ASGGSIA 1081

Query: 464  GPSSSP 469
            G SS P
Sbjct: 1082 GGSSCP 1087


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 91/361 (25%), Positives = 127/361 (35%), Gaps = 51/361 (14%)

Query: 120  SLVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGSASTPVQGSIPEGKPLRTLL 179
            S  P    PQ  +       +++     P  ++ PT       TP   S P G P    L
Sbjct: 710  STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT-----GVTPAPSSAPPGTPQ---L 761

Query: 180  GDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQM 239
              P P+ S  A       + S A       T P PH+ +++A           P   PQ 
Sbjct: 762  PTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA-----------PALHPQR 810

Query: 240  APAFAAFPAFGGQTPSQ--GGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQG 297
             P+    P      P Q   G A   +  S     + G  PP G  S QA P        
Sbjct: 811  PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP-GPHSLQAGPLLQHPGPP 869

Query: 298  TPFGATPLAPASQPNSLADVGSFLGPGVP--AAGVPSSLFGMAGQVPPLQSVTMGGGGGS 355
             PFG  P A   Q    A +G+      P  +  +P+S   +  Q PP +          
Sbjct: 870  QPFGLPPQASQGQ----APLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL------P 919

Query: 356  STGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFAS 415
               LA      P T P  Q P P  +   P+   P P F M++  P  P A+ P  + ++
Sbjct: 920  PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANLPP-PPALKPLSSLST 977

Query: 416  SFPAPLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPP 475
              P    PP   L+ Q          S  L   P +QP G++ +  +  P     AS PP
Sbjct: 978  HHPPSAHPPPLQLMPQ----------SQPLPSSP-AQPPGLTQSQNLPPPP----ASHPP 1022

Query: 476  T 476
            T
Sbjct: 1023 T 1023



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 62/240 (25%), Positives = 78/240 (32%), Gaps = 61/240 (25%)

Query: 267 SGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPF----GATPLAPASQPNSLADVGSFLG 322
           S     +  + PPA QA     P P+ +  GTP     G TP A A  P           
Sbjct: 727 SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 786

Query: 323 -PGVPAAGVPSSLFGMAGQV-----------------PPLQSVTMGGGGGSSTGLAFGAF 364
            P  P A VP +    A  +                 PPLQ +T             G+ 
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT-------------GSA 833

Query: 365 TNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTG----AFASSFPAP 420
             P     AQ PL    P  P+ L  GP   +   GP  P  +PP      A   + PA 
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGPHSLQAGP--LLQHPGPPQPFGLPPQASQGQAPLGTSPAA 891

Query: 421 LFPP---QTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPPTT 477
            +P    Q P  Q           SA   Q+P  +       P    P + P    PPTT
Sbjct: 892 AYPHTSLQLPASQ-----------SALQSQQPPRE------QPLPPAPLAMPHIKPPPTT 934



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 79/306 (25%), Positives = 103/306 (33%), Gaps = 58/306 (18%)

Query: 182  PAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAP 241
            P P L     ++ QP + SHA+        P PHS   +A   L       PF  P  A 
Sbjct: 822  PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS--LQAGPLLQHPGPPQPFGLPPQAS 879

Query: 242  AFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFG 301
                     GQ P           ++ P +S+     PA Q++ Q+Q  P    +  P  
Sbjct: 880  Q--------GQAP-----LGTSPAAAYPHTSL---QLPASQSALQSQQPP----REQPLP 919

Query: 302  ATPLA-PASQPNSLADVGSFLGPGV----PAAGVPSSLFGMAGQVPPLQSVTMGGGGGSS 356
              PLA P  +P     +     P      P    PS  F M   +PP     +      S
Sbjct: 920  PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANLPP--PPALKPLSSLS 976

Query: 357  TGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTG----- 411
            T     A   P        PLPS +P QP      PG   S   P  P + PPTG     
Sbjct: 977  THHPPSAHPPPLQLMPQSQPLPS-SPAQP------PGLTQSQNLPPPPASHPPTGLHQVA 1029

Query: 412  --------AFASSFPAPLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMT 463
                     F    P P+ PP  P       +S    G     Q P S  A  ++   + 
Sbjct: 1030 PQPPFAQHPFVPGGPPPITPPTCP------STSTPPAGPGTSAQPPCSGAA--ASGGSIA 1081

Query: 464  GPSSSP 469
            G SS P
Sbjct: 1082 GGSSCP 1087


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 91/352 (25%), Positives = 119/352 (33%), Gaps = 35/352 (9%)

Query: 147  PPDQVKGPTYT---KGSASTPVQGS-IPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHA 202
            PP     P  T   KG+++ P      P+G P  T L   AP+   A    + P  +   
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA----TLPSPKGGP 1071

Query: 203  RTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAP----AFAAFPAFGGQTPSQGG 258
             T   +    PP ++            GG    +P+ AP    A    P  G  TP   G
Sbjct: 1072 ATPSLKGAPTPPAATPPSPK-------GGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124

Query: 259  FANFDAFSSGPSSSVFGSLPPAGQASFQAQ--PTPAGSSQGTPFGATPLAPASQPNS--- 313
                 A +         + PP G  +  A   P+P G     P    P  PA+ P S   
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184

Query: 314  -LADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGG-----GGSSTGLAFGAFTNP 367
             LA       P  PAA  PS   G+A   P     T         GG +T    GA T P
Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244

Query: 368  FTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAPLFPPQTP 427
               P +    P+T P  P G AP P      +  G     P  GA   +   P  P   P
Sbjct: 1245 AATPPSPKGGPATPP--PKG-APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301

Query: 428  LVQQQNGSSFGDLGS--AKLGQRPLSQPAGISTNPFMTGPSSSPFASKPPTT 477
                  G+      +  +  G      P G  T P +T PS     + P TT
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 94/353 (26%), Positives = 117/353 (33%), Gaps = 37/353 (10%)

Query: 147  PPDQVKGPTYT---KGSASTPVQG-SIPEGKPLR-TLLGDPAPSLSVAASTSSQPVSQSH 201
            PP     P  T   KG+ +TP      P+G P   +L G P P  +   S    P + S 
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099

Query: 202  ARTSQARSTQPP---------PHSSVKKASTDLLADIGGD-----PFAAPQMAPAFAAFP 247
                   +  PP         PH               G      P  AP    A    P
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159

Query: 248  AFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPA---GSSQGTPFGATP 304
              G  TP   G     A +         +  P G  +  A   P+   G +  +P GA P
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA-P 1218

Query: 305  LAPASQPNS----LADVGSFLGPGVPAAGVPSSLFGMAGQVP-----PLQSVTMGGGGGS 355
              PA+ P S    LA       P  PAA  PS   G A   P     P  +      GG 
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278

Query: 356  STGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFAS 415
            +T    GA       P +    P+T+P  P G AP P      +  G P   PP GA   
Sbjct: 1279 ATPPHKGAPNPAVVTPPSPKGGPATSP--PKG-APTPPAATPPSPKGSPGTPPPKGAPTP 1335

Query: 416  SFPAPLFPPQTPLVQQQNGSSFG--DLGSAKLGQRPLSQPAGISTNPFMTGPS 466
                P  P  TP +     SS G     S+K G  P +        P MT PS
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS 1388



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 86/373 (23%), Positives = 126/373 (33%), Gaps = 75/373 (20%)

Query: 147  PPDQVKGPTYTKGSASTPVQGSIPEGK-PLRTLLGDPAPSLSVAASTSSQPVSQSHARTS 205
            PP     PT +  +  +P   ++P  + P  +++  P P    A     Q  + S   +S
Sbjct: 858  PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS 917

Query: 206  QARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQGGFANFDAF 265
              ++   P    +  + +         P  AP    A    P  G  TPS   +A     
Sbjct: 918  PKKARATPAPKGIPASPS---------PKGAPTPPAATPPSPKGGPATPSPK-WAPTPPA 967

Query: 266  SSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAPASQPNSLADVGSFLGPGV 325
            ++ PS       P  G A+    P+P G+   TP  ATP +P   P + +  G+   P V
Sbjct: 968  ATPPS-------PKGGPAT----PSPKGAP--TPPAATPPSPKGGPATPSPKGAPTPPAV 1014

Query: 326  ----PAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLAFGAFTNPF------------- 368
                P     ++ F      PP  +     G  ++T L  GA T P              
Sbjct: 1015 TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074

Query: 369  ------TAPAAQSPLPSTNPFQPN---------GLAPGPGFGMSS----AGPGFPQAVPP 409
                  T PAA  P P   P  P+            P P  G+++      P  P A PP
Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP 1134

Query: 410  TGAFASSFPAPLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPS--- 466
            +     + P P   P TP     +            G      P G  T P  T PS   
Sbjct: 1135 SPKGGLATPPPKGAPTTPAATPPSPK----------GGLATPPPKGAPTTPAATPPSPKG 1184

Query: 467  --SSPFASKPPTT 477
              ++P     PTT
Sbjct: 1185 GLATPSPKGAPTT 1197



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 94/374 (25%), Positives = 128/374 (34%), Gaps = 63/374 (16%)

Query: 154  PTYTKGSASTPVQGSIPEGK--PLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQA---- 207
            P     S + PV  S P+    PL TL+   AP +  +  + S P + +   T +     
Sbjct: 699  PLVPTASENCPVAPS-PQNTCAPLATLV--LAPEIPKSVPSPSLPPAGTPPGTKKVDGIS 755

Query: 208  -RSTQPPPHSSVKKASTD------LLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQGGFA 260
              S   P  SS K+  T+        +  G   + A   +P   +      + P++ G A
Sbjct: 756  HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA 815

Query: 261  NFDA---FSSGPSSSVFGSLPPAGQASFQAQ------------PTPAGSSQGTPFGATPL 305
              D      S P S V  S  P    SFQ              P+P G+   TP   TPL
Sbjct: 816  GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP--TPSAVTPL 873

Query: 306  AP--ASQPNSLADVGSFL-------GPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSS 356
            +P   + P       S +       GP  PA     +L  M    P     T    G  +
Sbjct: 874  SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPAL-SMTSSSPKKARATPAPKGIPA 932

Query: 357  TGLAFGAFTNPFTAPAAQ-----SPLPSTNPFQPNGLAPGPGFGMSSAGPGF----PQAV 407
            +    GA T P   P +      +P P   P  P    P P  G ++  P      P A 
Sbjct: 933  SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT 992

Query: 408  PPTGAFASSFPAPLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPS- 466
            PP+     + P+P   P  P V            S K        P G ST P  T PS 
Sbjct: 993  PPSPKGGPATPSPKGAPTPPAVTPP---------SPKGSPAATPFPKGASTPPAATPPSP 1043

Query: 467  -SSPFASKPPTTNP 479
              SP A+  P   P
Sbjct: 1044 KGSPAATPLPKGAP 1057



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 85/360 (23%), Positives = 118/360 (32%), Gaps = 41/360 (11%)

Query: 147  PPDQVKGPTYTKGSASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTS---SQPVSQSHAR 203
            P      P++  G A TP   S   G  + +  GDP     +  S     + PV++  A 
Sbjct: 1369 PTPPAATPSHKGGPAMTPP--SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA 1426

Query: 204  TSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQGGFANFD 263
            T       PP  + V        +   G P  A   +      PA    +P +       
Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGGP--ATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484

Query: 264  AFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAPASQPNSLADVGSFLGP 323
            A SS P  +      PA  A   A   PA           P  P+S+ + +A   + L  
Sbjct: 1485 ATSSSPKKA------PATPAPMGAPTLPAVIPSSPK--EVPATPSSRRDPIAPTATLLSK 1536

Query: 324  GVPAA------------GVPSSLFGMAGQVPPLQSVTMGGGGGSS----TGLAFGAFTNP 367
              PA              VPS     A   P     T      SS    T   +    +P
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596

Query: 368  ---FTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGP-GFPQAVPPTGAF---ASSFPAP 420
                  PA  SP P   P  P    P P  G ++  P G P + P T +    + + PA 
Sbjct: 1597 KELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656

Query: 421  LFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPS-SSPFASKPPTTNP 479
            +       V Q +       G   L +  L  PA  ST P +T P+   P   K   T+P
Sbjct: 1657 VTCKMGATVPQASKGLPAKKGPTAL-KEVLVAPAPEST-PIITAPTRKGPQTKKSSATSP 1714



 Score = 32.7 bits (73), Expect = 0.75
 Identities = 78/325 (24%), Positives = 110/325 (33%), Gaps = 70/325 (21%)

Query: 191 STSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAPAFAAFPAFG 250
           +T + P ++      QA +   P  S++  + T  L   G  P   P  +PA        
Sbjct: 5   ATETVPATEQELPQPQAETAVLPMSSAL--SVTAALGQPG--PTLPPPCSPA-------- 52

Query: 251 GQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGT--PFGATPLAPA 308
              P Q   +  +  S  PS S   S P          P P  SS GT  P G  P AP 
Sbjct: 53  ---PQQCPLSAANQASPFPSPSTIASTP-------LEVPFPQSSS-GTALPLGTAPEAPT 101

Query: 309 SQPN---------SLADVGSFLGP---GVPAAGVPSSLFGMA-------GQVPP-----L 344
             PN         +LA     + P   G P++  P +L  +A          PP      
Sbjct: 102 FLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP 161

Query: 345 QSVTMGGGGGSSTGLAFGAFTNPFT----APAAQSPLPSTNPFQPNGLAP------GPGF 394
            SV +   G   T  A  A + P T     P+   P P   P  P  ++        P  
Sbjct: 162 PSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMA 221

Query: 395 GMSSAGPGFPQAVPPTGAFASSFPAPLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPA 454
            + S     PQ  P T    +S         + L+  QN  S    G       P+S PA
Sbjct: 222 SIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKG-------PVSPPA 274

Query: 455 GISTN----PFMTGPSSSPFASKPP 475
            +S +    P +T    +   + PP
Sbjct: 275 ALSLSTQSLPVVTSSQKTAGPNTPP 299


>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
           sapiens]
          Length = 907

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 85/302 (28%), Positives = 115/302 (38%), Gaps = 57/302 (18%)

Query: 156 YTKGSASTPVQGS--IPEGKPLRTLLG-----DPAPSLSVA-ASTSSQPVSQSHARTSQA 207
           ++  + S+P QG+  +PE      LL       P+P+ + + A   S  V         +
Sbjct: 589 FSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGS 648

Query: 208 RSTQPPPHS---SVKKASTDLLADIGGDPFAAPQMAPAFAA--------FPAFGGQTPSQ 256
            +++P P S   S   AS DLLA  GG  F AP  +P   A        F A  G TPS 
Sbjct: 649 SASEPQPASQAASSSSASADLLAGFGGS-FMAPSPSPVTPAQNNLLQPNFEAAFGTTPST 707

Query: 257 GGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAPASQPNSLAD 316
              ++FD        SVF  L           PT A + Q  P    P +PA   +    
Sbjct: 708 SSSSSFDP-------SVFDGLGDL------LMPTMAPAGQPAPVSMVPPSPAMAASKA-- 752

Query: 317 VGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSP 376
           +GS L   +  A +  +L G++G       +    G    TG   GA   P  APA  S 
Sbjct: 753 LGSDLDSSL--ASLVGNL-GISGTTTKKGDLQWNAGEKKLTG---GANWQPKVAPATWSA 806

Query: 377 -LPSTNPFQ---------------PNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAP 420
            +P + P Q               P+   PG GFGM  AG G P        FA     P
Sbjct: 807 GVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRP 866

Query: 421 LF 422
            F
Sbjct: 867 PF 868



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 77/320 (24%), Positives = 116/320 (36%), Gaps = 48/320 (15%)

Query: 182 PAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAP 241
           PA S   AA  +  PV+ +    S      P   S+      DL A +     + P + P
Sbjct: 452 PAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFA-MKPPETSVPVVTP 510

Query: 242 AFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFG 301
             +  P      PS        A ++  +++   +      A+    P PA    G  F 
Sbjct: 511 TASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATTAP-PALDIFGDLFE 569

Query: 302 ATP-LAPASQPNS-----LADVGSFLGPGVPAAGVPSS-----LFGMAGQVPPLQSVTMG 350
           +TP +A A +P++     L    +F  P   A+ VP S     L  +     P  + T  
Sbjct: 570 STPEVAAAPKPDAAPSIDLFSTDAFSSPPQGASPVPESSLTADLLSVDAFAAPSPATTAS 629

Query: 351 GGGGSSTGLA--FG-AFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAV 407
                S+G+   FG AF +  + P   S   S++    + LA   GFG            
Sbjct: 630 PAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLA---GFG------------ 674

Query: 408 PPTGAFASSFPAPLFPPQTPLVQQQNGSSFGDLGSAK------------LGQ--RPLSQP 453
              G+F +  P+P+ P Q  L+Q    ++FG   S              LG    P   P
Sbjct: 675 ---GSFMAPSPSPVTPAQNNLLQPNFEAAFGTTPSTSSSSSFDPSVFDGLGDLLMPTMAP 731

Query: 454 AGISTNPFMTGPSSSPFASK 473
           AG      M  PS +  ASK
Sbjct: 732 AGQPAPVSMVPPSPAMAASK 751



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 84/352 (23%), Positives = 114/352 (32%), Gaps = 96/352 (27%)

Query: 157 TKGSASTPVQGSIPEGKPLRTLLGDPAPSLSVAAS-----TSSQPVSQ--------SHAR 203
           +K S +T V    P   P +T+   P   L   AS     ++S+P S         S   
Sbjct: 303 SKSSPATTVTS--PNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGG 360

Query: 204 TSQARSTQPPPHSSVKKASTDLLADIG-------------GDPFAAPQMAPAFAAFPAFG 250
            + A +  PPP +    A  DLL +                DPFA     P   A  A  
Sbjct: 361 AAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATA 420

Query: 251 GQTPSQGGFANF---------DAFSSGPSSSVFGSLPPAGQ-ASFQAQPTPAGSSQGTPF 300
             + S                DAF++ P     G  P A + A+  A PTP  ++     
Sbjct: 421 SASASTTTTVTAVTAEVDLFGDAFAASP-----GEAPAASEGAAAPATPTPVAAALDACS 475

Query: 301 GATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLA 360
           G  P AP+               G   A     LF M    PP  SV             
Sbjct: 476 GNDPFAPSE--------------GSAEAAPELDLFAMK---PPETSV------------- 505

Query: 361 FGAFTNPFTAPAAQS--PLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFP 418
                 P   P A +  P+P+T P      +P P    ++A      A   T    S+  
Sbjct: 506 ------PVVTPTASTAPPVPATAP------SPAPAVAAAAAATTAATAAATTTTTTSAAT 553

Query: 419 APLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQP-AGISTNPFMTGPSSSP 469
           A   PP   +        FGDL  +        +P A  S + F T   SSP
Sbjct: 554 ATTAPPALDI--------FGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSSP 597


>gi|23510333 pygopus homolog 2 [Homo sapiens]
          Length = 406

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 70/217 (32%), Positives = 82/217 (37%), Gaps = 54/217 (24%)

Query: 285 FQAQPTP------AGSSQGTPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMA 338
           F   PTP      A +     FGA  +  A+ P        FLG  VP  G      GMA
Sbjct: 61  FAPPPTPMVDHLVASNPFEDDFGAPKVGVAAPP--------FLGSPVPFGGFRVQ-GGMA 111

Query: 339 GQVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSS 398
           GQVPP    + GGGGG                P  + P     PF PN +  GP F M  
Sbjct: 112 GQVPP--GYSTGGGGGPQ--------------PLRRQP----PPFPPNPM--GPAFNMPP 149

Query: 399 AGPGFPQAVPPTGAFASS-FPAPL---FPPQTPLVQQQNGSSFGDLGSAKLGQRP----- 449
            GPG+P   P    F S  F  PL   F P +  +       FG + S  +GQ P     
Sbjct: 150 QGPGYPP--PGNMNFPSQPFNQPLGQNFSPPSGQMMPGPVGGFGPMISPTMGQPPRAELG 207

Query: 450 ---LSQPAGISTNPFMTGPSSSP---FASKPPTTNPF 480
              LSQ       PF   P   P     S PP T+PF
Sbjct: 208 PPSLSQRFAQPGAPFGPSPLQRPGQGLPSLPPNTSPF 244


>gi|6806913 centaurin, alpha 1 [Homo sapiens]
          Length = 374

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 36/124 (29%), Positives = 62/124 (50%), Gaps = 10/124 (8%)

Query: 31  RRVRELGGCSQAGNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPHRVKSISMTT 90
           R V EL    + GN  C +C      +   T+G F+C +CSG+ R +    +VKS+ +  
Sbjct: 7   RAVLEL--LQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDA 64

Query: 91  FTEPEVVFLQSRGNEVCRKIWLGLFDARTSLV---PDSRDPQKVKE-FLQEKYEKKRWYV 146
           + E +V F+ S GN+  R      F+++       P   D Q ++E +++ KYE++ +  
Sbjct: 65  WEEAQVEFMASHGNDAAR----ARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIY 120

Query: 147 PPDQ 150
           P  Q
Sbjct: 121 PEKQ 124


>gi|38373671 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 86/317 (27%), Positives = 113/317 (35%), Gaps = 51/317 (16%)

Query: 180 GDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQM 239
           G  AP++   A     P    + +T     ++ PP S    AST            AP  
Sbjct: 33  GSTAPAIPYGAYNGPVP---GYQQTPPQGMSRAPPSSGAPPASTA----------QAPCG 79

Query: 240 APAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGS-LPPAGQASFQAQP---TPAGSS 295
             A+  F    GQ   Q G ++       P S  FGS L P G      QP    P  + 
Sbjct: 80  QAAYGQF----GQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQ 135

Query: 296 QGTPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSS-------LFGM--AGQVPPLQS 346
             T      ++ A  P   A   S LG G P +   +S       L+G    GQ PPL S
Sbjct: 136 VATQLSGMQISGAVAP---APPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPL-S 191

Query: 347 VTMGGGGGSSTGLAFGAFTNPFTAPAAQSP-LPS-TNPFQPNGLAPGPGFGMSSAGPGFP 404
              G  G  +   +  +  + FT PA+  P LPS T P  P     GP     +     P
Sbjct: 192 QAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPP 251

Query: 405 QAVPPTGAFASSFPA--PLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFM 462
           QA+PP            P+  PQ P  Q Q   SFG          P   P      P+ 
Sbjct: 252 QALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFG----------PARGPQSNYGGPY- 300

Query: 463 TGPSSSPFASKPPTTNP 479
             P++  F S+P    P
Sbjct: 301 --PAAPTFGSQPGPPQP 315



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 69/282 (24%), Positives = 94/282 (33%), Gaps = 50/282 (17%)

Query: 149 DQVKGPTYTKGSASTPVQGSIPEGKPLRTL---------LGDPAPSLSVAASTSSQPVSQ 199
           D   GP+ T      P  GS P G PL  +          G P  S  VA   S   +S 
Sbjct: 90  DVQNGPSSTVQMQRLP--GSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISG 147

Query: 200 SHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQGGF 259
           + A    +      P +S+  AS           +   Q  P   A    G QTP +   
Sbjct: 148 AVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAP 207

Query: 260 ANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAPASQPNSLADVGS 319
           +   +F+  P +S    LP          P   G S G P         SQPN ++    
Sbjct: 208 SQASSFT--PPASGGPRLPS------MTGPLLPGQSFGGP-------SVSQPNHVSSPPQ 252

Query: 320 FLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSPLPS 379
            L PG       + + G  G +PP+ S    G      G +FG    P            
Sbjct: 253 ALPPG-------TQMTGPLGPLPPMHSPQQPGYQPQQNG-SFGPARGP------------ 292

Query: 380 TNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAPL 421
               Q N   P P      + PG PQ +PP      + P+P+
Sbjct: 293 ----QSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPI 330


>gi|38373669 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 86/317 (27%), Positives = 113/317 (35%), Gaps = 51/317 (16%)

Query: 180 GDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQM 239
           G  AP++   A     P    + +T     ++ PP S    AST            AP  
Sbjct: 33  GSTAPAIPYGAYNGPVP---GYQQTPPQGMSRAPPSSGAPPASTA----------QAPCG 79

Query: 240 APAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGS-LPPAGQASFQAQP---TPAGSS 295
             A+  F    GQ   Q G ++       P S  FGS L P G      QP    P  + 
Sbjct: 80  QAAYGQF----GQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQ 135

Query: 296 QGTPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSS-------LFGM--AGQVPPLQS 346
             T      ++ A  P   A   S LG G P +   +S       L+G    GQ PPL S
Sbjct: 136 VATQLSGMQISGAVAP---APPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPL-S 191

Query: 347 VTMGGGGGSSTGLAFGAFTNPFTAPAAQSP-LPS-TNPFQPNGLAPGPGFGMSSAGPGFP 404
              G  G  +   +  +  + FT PA+  P LPS T P  P     GP     +     P
Sbjct: 192 QAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPP 251

Query: 405 QAVPPTGAFASSFPA--PLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFM 462
           QA+PP            P+  PQ P  Q Q   SFG          P   P      P+ 
Sbjct: 252 QALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFG----------PARGPQSNYGGPY- 300

Query: 463 TGPSSSPFASKPPTTNP 479
             P++  F S+P    P
Sbjct: 301 --PAAPTFGSQPGPPQP 315



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 69/282 (24%), Positives = 94/282 (33%), Gaps = 50/282 (17%)

Query: 149 DQVKGPTYTKGSASTPVQGSIPEGKPLRTL---------LGDPAPSLSVAASTSSQPVSQ 199
           D   GP+ T      P  GS P G PL  +          G P  S  VA   S   +S 
Sbjct: 90  DVQNGPSSTVQMQRLP--GSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISG 147

Query: 200 SHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQGGF 259
           + A    +      P +S+  AS           +   Q  P   A    G QTP +   
Sbjct: 148 AVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAP 207

Query: 260 ANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAPASQPNSLADVGS 319
           +   +F+  P +S    LP          P   G S G P         SQPN ++    
Sbjct: 208 SQASSFT--PPASGGPRLPS------MTGPLLPGQSFGGP-------SVSQPNHVSSPPQ 252

Query: 320 FLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSPLPS 379
            L PG       + + G  G +PP+ S    G      G +FG    P            
Sbjct: 253 ALPPG-------TQMTGPLGPLPPMHSPQQPGYQPQQNG-SFGPARGP------------ 292

Query: 380 TNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAPL 421
               Q N   P P      + PG PQ +PP      + P+P+
Sbjct: 293 ----QSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPI 330


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 97/357 (27%), Positives = 130/357 (36%), Gaps = 58/357 (16%)

Query: 154  PTYTKGSASTPVQGSIPEG-------KPLRTLLGDPAPSLSVAAS-----TSSQPVSQSH 201
            PT T G   TP  G+           +PL  L+  P+P +S +A      T S P+    
Sbjct: 1346 PTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPS 1405

Query: 202  ARTSQARSTQPPPHSS--VKKASTDLLADIGGD-PFAAPQMAPAFAAFPAFGGQTPSQGG 258
            +    A S  P P+SS      S+ +   +    P + P   PA A+ P      P    
Sbjct: 1406 SLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPL---TIPIS-- 1460

Query: 259  FANFDAFSSGPS--SSVFGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAPASQPNSLAD 316
             A     +SGP+  +SV   L P   A+    P+ A S       A  L  A+ P+    
Sbjct: 1461 -APLTVSASGPALLTSVTPPLAPVVPAA-PGPPSLAPSGASPSASALTLGLATAPS---- 1514

Query: 317  VGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSP 376
            + S   PG P    P+S       VP L S        S   +   A  +PF  P+A +P
Sbjct: 1515 LSSSQTPGHPLLLAPTS-----SHVPGLNSTV--APACSPVLVPASALASPF--PSAPNP 1565

Query: 377  LPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAPLFP------------- 423
             P+    Q + LAP      + A P  P A P T   A S   PL P             
Sbjct: 1566 APA----QASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPV 1621

Query: 424  ---PQTPLVQQQNGSSFG-DLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPPT 476
                QTP+      S+ G  L SA     P    A  ST   +  P  SP  S   T
Sbjct: 1622 LASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPAST 1678



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 62/250 (24%), Positives = 91/250 (36%), Gaps = 20/250 (8%)

Query: 148  PDQVKGPTYTKGSASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQA 207
            P  V  P+ T+     PV   +P     +TL   PA + ++  S+ SQ +S         
Sbjct: 1651 PTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGP 1710

Query: 208  RSTQP---PPHSSVKKASTDLLADIGGDPFAAPQ---MAPAFAAFPAFGGQTPSQGGFAN 261
              TQ     P SS+       L+   G P    Q   +APA    PA      S  G A 
Sbjct: 1711 FPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPA------SPVGPAP 1764

Query: 262  FDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAPASQPNSLADVGSFL 321
                +  P+SS    L PA   +    P P  +          LAPAS  +  +   S +
Sbjct: 1765 AHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLV 1824

Query: 322  GPGVPAAGVPSSLFG---MAGQVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSPLP 378
                 AA +P ++     ++   P   ++  G     ST  +FG        P  Q P P
Sbjct: 1825 VSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGG-----PRPRRQPPPP 1879

Query: 379  STNPFQPNGL 388
              +PF  + L
Sbjct: 1880 PRSPFYLDSL 1889



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 87/336 (25%), Positives = 116/336 (34%), Gaps = 49/336 (14%)

Query: 160  SASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVK 219
            + S P+  S+P   P       PAP+ +      S P++ S +  +   S  PP    V 
Sbjct: 1430 TVSVPLSSSLPISVPTTL----PAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVP 1485

Query: 220  KA-STDLLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQGGF-ANFDAFSSGPSSSVFGSL 277
             A     LA  G  P A+        A      QTP      A   +   G +S+V  + 
Sbjct: 1486 AAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPAC 1545

Query: 278  PP------AGQASFQAQPTPAGS--------SQGTPFGATPLAPASQPNSLADVGSFLGP 323
             P      A  + F + P PA +        S  +   ATPLAP + P +     S   P
Sbjct: 1546 SPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPS---P 1602

Query: 324  GVPAAGVPSSLFGMAGQVPPLQSV-----TMGGGGGSSTGLAFGA---FTNPFTAPAAQ- 374
              P A +P  L    G  P L S       M       T LA  +      P  AP++  
Sbjct: 1603 APPLAPLPV-LAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQ 1661

Query: 375  --------SPLPSTNPFQPNGLAPG--PGFGMSSA------GPGFPQAVPPTGAFASSFP 418
                    SPLPS    Q   LAP   P  G SS       G G PQ   PT   + +  
Sbjct: 1662 TMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPA 1721

Query: 419  APLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPA 454
            + L P     +    G   G   +  L   P   PA
Sbjct: 1722 SSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPA 1757



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 71/247 (28%), Positives = 93/247 (37%), Gaps = 33/247 (13%)

Query: 183  APSLS---VAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFA--AP 237
            AP+ S   V AS  + P   S    + A+++   P SS  +A    LA +     A  AP
Sbjct: 1542 APACSPVLVPASALASPFP-SAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAP 1600

Query: 238  QMAPAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQG 297
              AP  A  P      PS G  A   A S  P   +  S  P G +   A P PA +   
Sbjct: 1601 SPAPPLAPLPVLA---PSPGA-APVLASSQTPVPVMAPSSTP-GTSLASASPVPAPTPVL 1655

Query: 298  TPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSST 357
             P     + PA  P+ L                P+S   +A  + P  + T+GG   S T
Sbjct: 1656 APSSTQTMLPAPVPSPLPS--------------PASTQTLA--LAPALAPTLGGSSPSQT 1699

Query: 358  -GLAFGAFTNPF-TAPAAQSPLPS--TNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAF 413
              L  G    PF T   + +P  S    P Q   LAPGP  G +      P   PP    
Sbjct: 1700 LSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAP--APPLAPA 1757

Query: 414  ASSFPAP 420
            +   PAP
Sbjct: 1758 SPVGPAP 1764



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 59/201 (29%), Positives = 80/201 (39%), Gaps = 39/201 (19%)

Query: 279  PAGQASFQAQPTPAGSSQGTPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMA 338
            P G    +  P P  S+Q TP     + PAS   S +  G    P +PA+  P  +    
Sbjct: 1018 PLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGP---PLIPASRPPGPVL--- 1071

Query: 339  GQVPPLQ--SVTMGGGGGSSTGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGM 396
              +PPLQ  S ++     S  G+  G  + P T   +  P P      P  L+P P  G 
Sbjct: 1072 --LPPLQPNSGSLPQVLPSPLGVLSGT-SRPPTPTLSLKPTPPA----PVRLSPAPPPGS 1124

Query: 397  SS--------AGPGFPQAVPPT------GAFASSFPAPLFPPQ----TPLVQQQNGS--- 435
            SS         G  FP A   T       A  ++ PAP   PQ    +P +Q +  S   
Sbjct: 1125 SSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEV 1184

Query: 436  -SFGDLGSAKLGQRPLSQPAG 455
             S G L  A L QRP++   G
Sbjct: 1185 VSIGQL--ASLAQRPVANAGG 1203



 Score = 37.0 bits (84), Expect = 0.040
 Identities = 60/273 (21%), Positives = 89/273 (32%), Gaps = 29/273 (10%)

Query: 154  PTYTKGSASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPP 213
            P     SA      S P   P +  L  PA S S A +T   P++    +T+    +  P
Sbjct: 1547 PVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAP--QTAILAPSPAP 1604

Query: 214  PHSSVKKASTDLLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSV 273
            P +         L  +   P AAP +A +    P     +      A     S+ P  + 
Sbjct: 1605 PLAP--------LPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLA-----SASPVPAP 1651

Query: 274  FGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAPASQPN---SLADVGSFLGPGVPAAGV 330
               L P+   +    P P+            LAPA  P    S       LG G P    
Sbjct: 1652 TPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPF 1711

Query: 331  PSSLFGM--AGQVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGL 388
            P+    +  A  + P  + T+    G   G          T   + +P P   P  P G 
Sbjct: 1712 PTQTLSLTPASSLVPTPAQTLSLAPGPPLGP---------TQTLSLAPAPPLAPASPVGP 1762

Query: 389  APGPGFGMSSAGPGFPQAVPPTGAFASSFPAPL 421
            AP     ++ A        P +    +  PAP+
Sbjct: 1763 APAHTLTLAPASSSASLLAPASVQTLTLSPAPV 1795


>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
          Length = 804

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 30/106 (28%), Positives = 53/106 (50%), Gaps = 2/106 (1%)

Query: 43  GNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPP-HRVKSISMTTFTEPEVVFLQS 101
           GN HC +C  +   +  + +G+ +C  CSG+ R L     RV+S+ +  +    +  + S
Sbjct: 567 GNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSS 626

Query: 102 RGNEVCRKIWLGLFDARTSLVPDSRDPQKVKEFLQEKYEKKRWYVP 147
            GNE+   +W      RT    DS   +K + +++ KYE+K +  P
Sbjct: 627 IGNELANSVWEESSQGRTKPSVDSTREEK-ERWIRAKYEQKLFLAP 671


>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
          Length = 857

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 30/106 (28%), Positives = 53/106 (50%), Gaps = 2/106 (1%)

Query: 43  GNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPP-HRVKSISMTTFTEPEVVFLQS 101
           GN HC +C  +   +  + +G+ +C  CSG+ R L     RV+S+ +  +    +  + S
Sbjct: 620 GNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSS 679

Query: 102 RGNEVCRKIWLGLFDARTSLVPDSRDPQKVKEFLQEKYEKKRWYVP 147
            GNE+   +W      RT    DS   +K + +++ KYE+K +  P
Sbjct: 680 IGNELANSVWEESSQGRTKPSVDSTREEK-ERWIRAKYEQKLFLAP 724


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 91/310 (29%), Positives = 116/310 (37%), Gaps = 64/310 (20%)

Query: 154 PTYTKGSASTPVQGSIPEGKPLRTLL-----GDPAPSLSVAA-------------STSSQ 195
           PT T  + STP   +IP G   ++ L      +P P+   A              S  S 
Sbjct: 671 PTLTFSNTSTPTF-NIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSS 729

Query: 196 PVSQSHARTSQARSTQPPPHSSVK----KASTDLLADIGGDPFAAPQMAPAFAAF----- 246
               + A  + A +  P P S++K       T +    GG   +A  +    +AF     
Sbjct: 730 FTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPAS 789

Query: 247 --PAFGGQTP--------SQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQ 296
             PAFGG T         S G  A     SSG SSSVFGS  P+   +F     PAGS  
Sbjct: 790 SQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPS-PFTFGGSAAPAGSGS 848

Query: 297 GTPFGATPLAPASQPNSLADVGSF-LGPGVPAAGVPSSLF-GMAGQVPPLQSVTMGGGGG 354
              FG       + P S A  G+F  G G   +   S+ F G  GQ          G  G
Sbjct: 849 ---FGIN----VATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQ-------NALGTTG 894

Query: 355 SSTGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPG-------FGMSSAGPGFPQAV 407
            ST  AF   +   + P       +T  F  N  APG G       FG SSA       V
Sbjct: 895 QSTPFAFNVGSTTESKPVFGG--TATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGV 952

Query: 408 PPTGAFASSF 417
            P G+ A SF
Sbjct: 953 GPFGSAAPSF 962



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 66/254 (25%), Positives = 91/254 (35%), Gaps = 44/254 (17%)

Query: 171 EGKPLRTLLG-DPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADI 229
           + KP  TLLG  PAPS+  A  T + P  Q+   T    ++ P P            A  
Sbjct: 389 DSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSP------------APK 436

Query: 230 GGDPFAAPQMAPAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQP 289
               F     +P+  A PA    +P          F++ P S   G  PP    +     
Sbjct: 437 QSFLFGTQNTSPSSPAAPAASSASPMFKPI-----FTAPPKSEKEGPTPPGPSVT----- 486

Query: 290 TPAGSSQGTPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTM 349
             A SS   P   +  AP  QP     V S +G   P A VP          P  +  T 
Sbjct: 487 ATAPSSSSLPTTTSTTAPTFQP-----VFSSMG---PPASVPL-------PAPFFKQTTT 531

Query: 350 GGGGGSSTGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPP 409
                ++T      FT   +A +A +P+ S +P   +   P  GFG++S           
Sbjct: 532 PATAPTTTA---PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS 588

Query: 410 TGAFASS---FPAP 420
           T   AS    F AP
Sbjct: 589 TATAASQPFLFGAP 602



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 90/346 (26%), Positives = 119/346 (34%), Gaps = 67/346 (19%)

Query: 154 PTYTKGSASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPP 213
           P +T  +++T     I    P       PA    +  S SS  VS +   TS A +   P
Sbjct: 541 PLFTGLASATSAVAPITSASPSTDSASKPAFGFGIN-SVSSSSVSTT---TSTATAASQP 596

Query: 214 PHSSVKKASTDLLADIGGD--PFAAPQMAPAFAAFPAFGGQTPSQGGFANFDAFSSGPSS 271
                 +AS        G    F  P   P       F    P+    A     SS    
Sbjct: 597 FLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATS---SSAADF 653

Query: 272 SVFGSLPPAGQASFQAQPTPAGSSQGT-----PFGATPLAPASQPNSLADVGSFLGPGVP 326
           S FGS       +  +QPT   S+  T     PFG++  +P               P  P
Sbjct: 654 SGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPL--------------PSYP 699

Query: 327 AAGVPSSLFGMA-GQVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSPLPST----- 380
            A  P   FG A GQ P      +    GSS      A   P TAP   +P P++     
Sbjct: 700 GAN-PQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAP---TPAPASTIKIV 755

Query: 381 -----NPFQPN-GLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAPLFPPQTPLVQQQNG 434
                 P QP  G A    FG+ +    F       GA ASS PA  F   T +      
Sbjct: 756 PAHVPTPIQPTFGGATHSAFGLKATASAF-------GAPASSQPA--FGGSTAVF----- 801

Query: 435 SSFGDLGSAKLGQRPLSQPAGIST--------NPFMTGPSSSPFAS 472
            SFG   S+  G    +  +G S+        +PF  G S++P  S
Sbjct: 802 -SFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGS 846



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 74/335 (22%), Positives = 114/335 (34%), Gaps = 41/335 (12%)

Query: 160 SASTPVQGSIPEGKPLRTLLGDPAPSLSVAAST---SSQPVSQSHARTSQARSTQPPPHS 216
           +AS  V  + P  +P  T     A + S   S    S+ P+ +S  +  Q   + PP   
Sbjct: 292 AASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLES-LKKMQTPPSLPPCPE 350

Query: 217 SVKKASTDLLADIGGDPFAAPQMAPAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGS 276
           S   A+T+ L+         P   P+    P  G       G     +F S P +++ G 
Sbjct: 351 SAGAATTEALS---------PPKTPSL--LPPLGLSQSGPPGLLPSPSFDSKPPTTLLGL 399

Query: 277 LPPAGQA---SFQAQPTPAGSSQGTPFGATPLAPASQPNSLADVG--SFLGPGVPAAGVP 331
           +P          +A PT    +   P   +  +PA + + L      S   P  PAA   
Sbjct: 400 IPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSA 459

Query: 332 SSLFGMAGQVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPG 391
           S +F      PP         G +  G            P+  +  PS++          
Sbjct: 460 SPMFKPIFTAPPKSEKE----GPTPPG------------PSVTATAPSSSSLPTTTSTTA 503

Query: 392 PGFGMSSAGPGFPQAVPPTGAFASSFPAPLFPPQT--PLVQ--QQNGSSFGDLGSAKLGQ 447
           P F    +  G P +VP    F      P   P T  PL        S+   + SA    
Sbjct: 504 PTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPST 563

Query: 448 RPLSQPA-GISTNPFMTGPSSSPFASKPPTTNPFL 481
              S+PA G   N   +   S+  ++    + PFL
Sbjct: 564 DSASKPAFGFGINSVSSSSVSTTTSTATAASQPFL 598


>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 7 [Homo sapiens]
          Length = 663

 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 4/107 (3%)

Query: 43  GNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPP-HRVKSISMTTFTEPEVVFLQS 101
           GN HC +C  +   +  + +G  +C  CSG+ R L     RV+S+ +  +       + S
Sbjct: 452 GNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSS 511

Query: 102 RGNEVCRKIWLGLFDARTSLVPDSRDPQKVKE-FLQEKYEKKRWYVP 147
            GN++   IW G    RT   P  +  ++ KE +++ KYE+K +  P
Sbjct: 512 IGNDLANSIWEGSSQGRTK--PTEKSTREEKERWIRSKYEEKLFLAP 556


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
           sapiens]
          Length = 834

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 92/308 (29%), Positives = 117/308 (37%), Gaps = 62/308 (20%)

Query: 154 PTYTKGSASTPVQGSIPEGKPLRTLL-----GDPAPSLSVA----------ASTSSQPVS 198
           PT T  + STP   +IP G   ++ L      +P P+   A          A T S   S
Sbjct: 520 PTLTFSNTSTPTF-NIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSS 578

Query: 199 QSHARTSQ-ARSTQPPPHSSVK----KASTDLLADIGGDPFAAPQMAPAFAAF------- 246
            +   ++  A +  P P S +K       T +    GG   +A  +    +AF       
Sbjct: 579 FTFGNSAAPAAAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQ 638

Query: 247 PAFGGQTP--------SQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGT 298
           PAFGG T         S G  A     SSG SSSVFGS  P+   +F     PAGS    
Sbjct: 639 PAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPS-PFTFGGSAAPAGSGS-- 695

Query: 299 PFGATPLAPASQPNSLADVGSF-LGPGVPAAGVPSSLF-GMAGQVPPLQSVTMGGGGGSS 356
            FG       + P S A  G+F  G G   +   S+ F G  GQ          G  G S
Sbjct: 696 -FGIN----VATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQ-------NALGTTGQS 743

Query: 357 TGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPG-------FGMSSAGPGFPQAVPP 409
           T  AF   +   + P       +T  F  N  APG G       FG SSA       V P
Sbjct: 744 TPFAFNVGSTTESKPVFGG--TATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAP 801

Query: 410 TGAFASSF 417
            G+ A SF
Sbjct: 802 FGSAAPSF 809



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 66/254 (25%), Positives = 90/254 (35%), Gaps = 44/254 (17%)

Query: 171 EGKPLRTLLG-DPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADI 229
           +  P  TLLG  PAPS+  A  T + P  Q+   T    ++ P P            A  
Sbjct: 238 DSNPPTTLLGLIPAPSMVPATDTKAPPTLQAETTTKPQATSAPSP------------APK 285

Query: 230 GGDPFAAPQMAPAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQP 289
               F     +P+  A PA    +P          F++ P S   G  PP    S     
Sbjct: 286 QSFLFGTQNTSPSSPAAPAASSASPMFKPI-----FTAPPKSEKEGPTPPGPSVS----- 335

Query: 290 TPAGSSQGTPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTM 349
             A SS   P   +  AP  QP     V S +G   P A VP          P  +  T 
Sbjct: 336 ATAPSSSSLPTTTSTTAPTFQP-----VFSSMG---PPASVPL-------PAPFFKQTTT 380

Query: 350 GGGGGSSTGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPP 409
                ++T      FT   +A +A +P+ S +P   +   P  GFG++S           
Sbjct: 381 PATAPTTTA---PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS 437

Query: 410 TGAFASS---FPAP 420
           T   AS    F AP
Sbjct: 438 TATAASQPFLFGAP 451



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 90/343 (26%), Positives = 118/343 (34%), Gaps = 63/343 (18%)

Query: 154 PTYTKGSASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPP 213
           P +T  +++T     I    P       PA    +  S SS  VS +   TS A +   P
Sbjct: 390 PLFTGLASATSAVAPITSASPSTDSASKPAFGFGIN-SVSSSSVSTT---TSTATAASQP 445

Query: 214 PHSSVKKASTDLLADIGGD--PFAAPQMAPAFAAFPAFGGQTPSQGGFANFDAFSSGPSS 271
                 +AS        G    F  P   P       F    P+    A     SS    
Sbjct: 446 FLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATS---SSAADF 502

Query: 272 SVFGSLPPAGQASFQAQPTPAGSSQGT-----PFGATPLAPASQPNSLADVGSFLGPGVP 326
           S FGS       +  +QPT   S+  T     PFG++  +P               P  P
Sbjct: 503 SGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPL--------------PSYP 548

Query: 327 AAGVPSSLFGMA-GQVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSP-----LPS- 379
            A  P   FG A GQ P      +    GSS    FG    P  AP    P     +P+ 
Sbjct: 549 GAN-PQPAFGAAEGQPPGAAKPALTPSFGSS--FTFGNSAAPAAAPTPAPPSMIKIVPAH 605

Query: 380 -TNPFQPN-GLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAPLFPPQTPLVQQQNGSSF 437
              P QP  G A    FG+ +    F       GA ASS PA  F   T +       SF
Sbjct: 606 VPTPIQPTFGGATHSAFGLKATASAF-------GAPASSQPA--FGGSTAVF------SF 650

Query: 438 GDLGSAKLGQRPLSQPAGIST--------NPFMTGPSSSPFAS 472
           G   S+  G    +  +G S+        +PF  G S++P  S
Sbjct: 651 GAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGS 693



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 67/310 (21%), Positives = 105/310 (33%), Gaps = 38/310 (12%)

Query: 182 PAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAP 241
           PA   +   + S+ P+ +S  +  Q   + PP   S   A+T+ L+     P   P +  
Sbjct: 166 PASPPTSLLAPSTNPLLES-LKKMQTPPSLPPCPESAGAATTEALS-----PPKTPNL-- 217

Query: 242 AFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQA---SFQAQPTPAGSSQGT 298
                P  G       G     +F S P +++ G +P          +A PT    +   
Sbjct: 218 ----LPPLGLSQSGPPGLLPSPSFDSNPPTTLLGLIPAPSMVPATDTKAPPTLQAETTTK 273

Query: 299 PFGATPLAPASQPNSLADVG--SFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSS 356
           P   +  +PA + + L      S   P  PAA   S +F      PP         G + 
Sbjct: 274 PQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKE----GPTP 329

Query: 357 TGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASS 416
            G            P+  +  PS++          P F    +  G P +VP    F   
Sbjct: 330 PG------------PSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQ 377

Query: 417 FPAPLFPPQT--PLVQ--QQNGSSFGDLGSAKLGQRPLSQPA-GISTNPFMTGPSSSPFA 471
              P   P T  PL        S+   + SA       S+PA G   N   +   S+  +
Sbjct: 378 TTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS 437

Query: 472 SKPPTTNPFL 481
           +    + PFL
Sbjct: 438 TATAASQPFL 447


>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 4 [Homo sapiens]
          Length = 663

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 4/107 (3%)

Query: 43  GNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPP-HRVKSISMTTFTEPEVVFLQS 101
           GN HC +C  +   +  + +G  +C  CSG+ R L     RV+S+ +  +       + S
Sbjct: 452 GNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSS 511

Query: 102 RGNEVCRKIWLGLFDARTSLVPDSRDPQKVKE-FLQEKYEKKRWYVP 147
            GN++   IW G    +T   P  +  ++ KE +++ KYE+K +  P
Sbjct: 512 IGNDLANSIWEGSSQGQTK--PSEKSTREEKERWIRSKYEEKLFLAP 556


>gi|7661880 centaurin beta1 [Homo sapiens]
          Length = 740

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 63/250 (25%), Positives = 97/250 (38%), Gaps = 41/250 (16%)

Query: 7   KGPGPGGGVSGGKAEAEAASEVWCRRVRELGGCSQA--------GNRHCFECAQRGVTYV 58
           +GPG G G     + A   S    R  RE GG            GN  C +C +    + 
Sbjct: 373 RGPGQGSGHLAIGSAATLGSGGMARG-REPGGVGHVVAQVQSVDGNAQCCDCREPAPEWA 431

Query: 59  DITVGSFVCTTCSGLLRGLNPP-HRVKSISMTTFTEPEVVFLQSR-GNEVCRKIWLGLFD 116
            I +G  +C  CSG+ R L     +V+S+++ ++ EPE+V L    GN +  +I+    +
Sbjct: 432 SINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSW-EPELVKLMCELGNVIINQIYEARVE 490

Query: 117 ARTSLVPDSRDPQKVKE-FLQEKYEKKRWYVPPDQVKGPTYTKGSASTPVQGSIPEGKPL 175
           A     P     ++ KE ++  KY +K++     +++G    +G          P G+P 
Sbjct: 491 AMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGR---------PRGQP- 540

Query: 176 RTLLGDPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTD-LLADIGGDPF 234
                 P P           P      R    RS   PP   +       LL    G P 
Sbjct: 541 ------PVP-----------PKPSIRPRPGSLRSKPEPPSEDLGSLHPGALLFRASGHPP 583

Query: 235 AAPQMAPAFA 244
           + P MA A A
Sbjct: 584 SLPTMADALA 593


>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
          Length = 686

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 4/107 (3%)

Query: 43  GNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPP-HRVKSISMTTFTEPEVVFLQS 101
           GN HC +C  +   +  + +G  +C  CSG+ R L P   RV+S+ +  +       + S
Sbjct: 475 GNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVRSLELDDWPVELRKVMSS 534

Query: 102 RGNEVCRKIWLGLFDARTSLVPDSRDPQKVKE-FLQEKYEKKRWYVP 147
             N++   IW G    +T   P  +  ++ KE +++ KYE+K +  P
Sbjct: 535 IVNDLANSIWEGSSQGQTK--PSEKSTREEKERWIRSKYEEKLFLAP 579


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 74/267 (27%), Positives = 87/267 (32%), Gaps = 30/267 (11%)

Query: 231 GDPFAAPQMAPAFAAFPAFGG-QTPSQ----------GGFANFDAFSSGPSSSVFGSLPP 279
           G P AAP+  PA  A P  GG Q P            G           P  S     P 
Sbjct: 81  GAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV 140

Query: 280 AGQASFQAQPTPAGSSQGTPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAG 339
              A+  A P PA +    P G   LA  + P      G   GPG      P +   + G
Sbjct: 141 PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNG 200

Query: 340 QVPPLQSVTMGGGGGSSTGLAFGAFTNPFTAPAAQSPLPSTNPF-----QPNGLAPGPGF 394
               L S        S       A   P   PAA   +  T PF      P   AP P  
Sbjct: 201 SAALLNSHHAAAPAVSLVNNGPAALL-PLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPA 259

Query: 395 GMSSAGP-GFPQAVPPTGAFASSFPA-PLFPPQT-----PLVQQQNGSSFGDLGSAKLGQ 447
             + A P   P   PP  A  +  P  P  PP       P    QNG   G  G+A    
Sbjct: 260 APAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG---GSAGAAPAPA 316

Query: 448 RPLSQPAGISTNPFMTGPSSSPFASKP 474
                PAG+S  P   GP ++  A  P
Sbjct: 317 PAAGGPAGVSGQP---GPGAAAAAPAP 340



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 75/305 (24%), Positives = 94/305 (30%), Gaps = 45/305 (14%)

Query: 182 PAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGD-----PFAA 236
           PA  L      S+   +   A  + A   +P P    K A    LA   G      P   
Sbjct: 122 PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG 181

Query: 237 PQMAPAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQ 296
           P   P   A P             N    ++ P+ S+  + P A        P P  ++ 
Sbjct: 182 PGPGPGKPAGPGAAQTLNGSAALLN-SHHAAAPAVSLVNNGPAA------LLPLPKPAAP 234

Query: 297 GTPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSS 356
           GT     P   A+ P + A       P  PAA  P++    A   PP    T+    G  
Sbjct: 235 GTVIQTPPFVGAAAPPAPA------APSPPAAPAPAAP-AAAPPPPPPAPATLARPPGHP 287

Query: 357 TGLAFGAFTNPFTAPAAQSPLPSTNPFQ------PNGLAPGPGFGMSSAGPGFPQAVPPT 410
            G        P  APA   P  + N         P   A GP       GPG   A P  
Sbjct: 288 AG-------PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340

Query: 411 GAFASSFPAPLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPF 470
           G  A S P  +     P  Q    S             P S  A +   P M G   SP 
Sbjct: 341 GVKAES-PKRVVQAAPPAAQTLAASG------------PASTAASMVIGPTMQGALPSPA 387

Query: 471 ASKPP 475
           A  PP
Sbjct: 388 AVPPP 392



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 59/217 (27%), Positives = 74/217 (34%), Gaps = 28/217 (12%)

Query: 182 PAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAP 241
           PAP+   AA     P   + AR     +  P    +V   +    A  GG   AAP  AP
Sbjct: 261 PAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAA---AQNGGSAGAAPAPAP 317

Query: 242 AFAAFPAFGGQT-PSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQ---G 297
           A        GQ  P     A      +     V  + PPA Q    + P    +S     
Sbjct: 318 AAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGP 377

Query: 298 TPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSSL-FGMAGQVPPLQSVTMGGGGGSS 356
           T  GA P +PA+ P              PA G P+ L  G AG V    S T      ++
Sbjct: 378 TMQGALP-SPAAVP-------------PPAPGTPTGLPKGAAGAVTQSLSRT-----PTA 418

Query: 357 TGLAFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPG 393
           T     A   P T  A + P P  NP         PG
Sbjct: 419 TTSGIRATLTP-TVLAPRLPQPPQNPTNIQNFQLPPG 454


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 69/300 (23%), Positives = 116/300 (38%), Gaps = 46/300 (15%)

Query: 183 APSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMAPA 242
           +P  +    TSSQ   +  A  + A ++ PP   +   A+  LL   GG P      + +
Sbjct: 430 SPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLP-AGGAPTVFSFGSSS 488

Query: 243 FAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPFGA 302
             +     G+ PS    ++    + GP  S F  +PP+ +AS    PTPA         A
Sbjct: 489 LKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPS-KASL--APTPA---------A 536

Query: 303 TPLAPASQPNSLADVG---SFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGL 359
           +P+AP++   S    G   +     VP+   P+    M    PP            ST  
Sbjct: 537 SPVAPSAASFSFGSSGFKPTLESTPVPSVSAPN--IAMKPSFPP------------STSA 582

Query: 360 AFGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPA 419
                +  FTA A  +P+ S+    P  ++P            F  A  P  +   S P 
Sbjct: 583 VKVNLSEKFTAAATSTPVSSSQSAPP--MSP------------FSSASKPAASGPLSHPT 628

Query: 420 PLFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPPTTNP 479
           PL  P + +  + +        SA+    P+  P+ +  +P +T P++ P + +  +  P
Sbjct: 629 PLSAPPSSVPLKSSVLPSPSGRSAQGSSSPV--PSMVQKSPRITPPAAKPGSPQAKSLQP 686



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 91/383 (23%), Positives = 131/383 (34%), Gaps = 78/383 (20%)

Query: 160  SASTPVQGSIPEGKPLRTLLGDPAPSLSVAA----STSSQPVSQSHARTSQARSTQPPPH 215
            ++STP+  S        T +  P PS   AA    ++ S   +Q  A +S +   Q   +
Sbjct: 1611 TSSTPIASST-------TSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNN 1663

Query: 216  SSVKKASTDLLADIGGDPF----------------AAPQMAPAFAAFPAFGGQTP---SQ 256
            ++   ++T +   +                     A PQ++ +  + PAFG   P    Q
Sbjct: 1664 TATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQ 1723

Query: 257  GGFANFDAFSSGPSSSV---------FGSLPPAGQASFQAQPTPAGSSQGTPFGATPLAP 307
              F     F    SS+          F S+P  GQ    A  TP  S+ G+ FGA     
Sbjct: 1724 TTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQ---PASSTPT-STSGSVFGAASSTS 1779

Query: 308  ASQPNSLADVGSFLGPGV------PAAGVPSSLFGMAGQV------PPLQSVTMG----- 350
            +S   S        G G+      PA G  S  FG  G V          + T G     
Sbjct: 1780 SSSSFSFGQSSPNTGGGLFGQSNAPAFG-QSPGFGQGGSVFGGTSAATTTAATSGFSFCQ 1838

Query: 351  --GGGGSSTGLAFG-AFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAV 407
              G G S+TG  FG A +        QS   S + F       G GF     G     A 
Sbjct: 1839 ASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAA 1898

Query: 408  --PPTGAFASSFPAPLFPPQTPLVQQQNGSSFGDLGSAKLG-QRP-----------LSQP 453
               P  + +  F +      + L       +FG   S+  G Q+P            SQ 
Sbjct: 1899 NKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQG 1958

Query: 454  AGISTNPFMTGPSSSPFASKPPT 476
             G S+     G  ++P    PPT
Sbjct: 1959 FGFSSPNKTGGFGAAPVFGSPPT 1981



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 57/230 (24%), Positives = 81/230 (35%), Gaps = 52/230 (22%)

Query: 286 QAQPTPAGSSQGTPFGATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQ 345
           + QP   GS+  TP  +   AP     S A   + L P  PAA              P+ 
Sbjct: 425 ERQPKSPGSTPTTPTSSQ--APQKLDASAAAAPASLPPSSPAA--------------PIA 468

Query: 346 SVTMGGGGGSSTGLAFGAFTNPFTA----------------PAAQSPLPSTNPFQP---N 386
           + ++   GG+ T  +FG+ +   +A                 AA  P PST  F P    
Sbjct: 469 TFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKA 528

Query: 387 GLAPGP------------GFGMSSAGPGFPQAVPPTGAFASSFPAPLFPPQTPLVQQQNG 434
            LAP P             FG S   P       P+ +  +    P FPP T  V+    
Sbjct: 529 SLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLS 588

Query: 435 SSFGDLGS----AKLGQRPLSQPAGISTNPFMTGPSSSPF-ASKPPTTNP 479
             F    +    +     P   P   ++ P  +GP S P   S PP++ P
Sbjct: 589 EKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVP 638



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 79/351 (22%), Positives = 120/351 (34%), Gaps = 55/351 (15%)

Query: 159  GSASTPVQGSIPEGKPLRTLLGDPAPSLSVAASTSSQPVSQSHART---SQARSTQPP-- 213
            G  S P   S P G      +  P PS +  A+  + P ++  ++    S    ++P   
Sbjct: 1208 GQFSKPFSFS-PSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYE 1266

Query: 214  --PHSSVKKASTDLLADIGGDPFAAPQ--MAPAFAAFPAFGGQT---PSQGGFANFDAFS 266
              P SS     T       G+P A+    +AP+  A      +    PS+ G   F +  
Sbjct: 1267 AIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSL 1326

Query: 267  SGPSSSVFGSLPPAGQASFQAQPTPAGSS-----------QGTPFGATPLAPA-----SQ 310
            +G +   F  L   GQA    +PT   SS            G P G    AP      ++
Sbjct: 1327 AGETLGSFSGLR-VGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTE 1385

Query: 311  P--NSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLAFGAFTNPF 368
            P   S A   S      P A   +S   + G +P   + + G      T L+ G  +  F
Sbjct: 1386 PPVTSSATTTSV----APPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSF 1441

Query: 369  TAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVP-PTGAFASSFPAPLFPPQTP 427
             +    S +P + P                  P    A P PT     SF + L    TP
Sbjct: 1442 GSQQTNSTVPPSAP------------------PPTTAATPLPTSFPTLSFGSLLSSATTP 1483

Query: 428  LVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPPTTN 478
             +    G S  +  S+ L ++P       S    +    S+     PP T+
Sbjct: 1484 SLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTS 1534



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 98/413 (23%), Positives = 144/413 (34%), Gaps = 100/413 (24%)

Query: 160  SASTPVQGSIPEGKPLRTLL------GDPAPSLSVAASTSSQPVSQSHARTSQARSTQPP 213
            S +T     IP+G     L       G P+PS  ++A  ++   +      SQA +    
Sbjct: 1052 SVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTL 1111

Query: 214  PHSSVKKA-------------STDLLADIGGDPFAA-----PQMAPAFAAFPAFG----- 250
              S++K               +T   A     P++      P + P  A     G     
Sbjct: 1112 TESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINS 1171

Query: 251  ----GQTPSQGGFANFD----------AFSSGPSSS----------------VFGSLPPA 280
                G TP+ G  ++ D          A +S PS+S                 FG + P 
Sbjct: 1172 LKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPT 1231

Query: 281  GQASFQ----AQPTPAGSSQGTPF----GATP---LAPASQPNSLADVGSFLGPGVPAA- 328
              ++F     A P+   SSQ   F    G+ P     P S P S     S   PG PAA 
Sbjct: 1232 PSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAAS 1291

Query: 329  --------GVPSSLFGMAGQVPP-------LQSVTMGGGGGSSTGLAFGA---FTNPFTA 370
                    G   S      + PP         S   G   GS +GL  G     T P T 
Sbjct: 1292 SSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKP-TN 1350

Query: 371  PAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSF----PAPLFPPQT 426
             A+ + L ST P + +G+    GF  ++         PP  + A++     PA      T
Sbjct: 1351 KASSTSLTSTQPTKTSGVP--SGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSST 1408

Query: 427  PLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSS--PFASKPPTT 477
             +      +S G  G    G   LS  AG ++  F +  ++S  P ++ PPTT
Sbjct: 1409 AVFGSLPVTSAGSSGVISFGGTSLS--AGKTSFSFGSQQTNSTVPPSAPPPTT 1459


>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 9 [Homo sapiens]
          Length = 684

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 4/107 (3%)

Query: 43  GNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPP-HRVKSISMTTFTEPEVVFLQS 101
           GN HC +C  +   +  + +G  +C  CSG+ R       RV+S+ +  +       + S
Sbjct: 475 GNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSS 534

Query: 102 RGNEVCRKIWLGLFDARTSLVPDSRDPQKVKE-FLQEKYEKKRWYVP 147
            GNE+   IW G    +T   P  +  ++ KE +++ KYE+K +  P
Sbjct: 535 IGNELANSIWEGSSQGQTK--PSIKSTREEKEWWIRSKYEEKLFLAP 579


>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 10 [Homo sapiens]
          Length = 684

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 4/107 (3%)

Query: 43  GNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPP-HRVKSISMTTFTEPEVVFLQS 101
           GN HC +C  +   +  + +G  +C  CSG+ R       RV+S+ +  +       + S
Sbjct: 475 GNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSS 534

Query: 102 RGNEVCRKIWLGLFDARTSLVPDSRDPQKVKE-FLQEKYEKKRWYVP 147
            GNE+   IW G    +T   P  +  ++ KE +++ KYE+K +  P
Sbjct: 535 IGNELANSIWEGSSQGQTK--PSIKSTREEKEWWIRSKYEEKLFLAP 579


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,750,248
Number of Sequences: 37866
Number of extensions: 1542558
Number of successful extensions: 9259
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 890
Number of HSP's that attempted gapping in prelim test: 6936
Number of HSP's gapped (non-prelim): 2641
length of query: 481
length of database: 18,247,518
effective HSP length: 106
effective length of query: 375
effective length of database: 14,233,722
effective search space: 5337645750
effective search space used: 5337645750
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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