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Search of human proteins with 91208418
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|91208418 transcription elongation regulator 1 isoform 2
[Homo sapiens]
(1077 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 2161 0.0
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 2149 0.0
gi|148727264 transcription elongation regulator 1-like [Homo sap... 274 3e-73
gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap... 140 6e-33
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap... 139 1e-32
gi|151301228 formin binding protein 3 [Homo sapiens] 130 5e-30
gi|148746195 trichohyalin [Homo sapiens] 99 2e-20
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 92 2e-18
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 85 4e-16
gi|163965366 nascent polypeptide-associated complex alpha subuni... 84 5e-16
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens] 84 7e-16
gi|7706501 WW domain binding protein 11 [Homo sapiens] 84 7e-16
gi|160707881 formin 2 [Homo sapiens] 84 9e-16
gi|148612835 zinc finger protein 207 isoform c [Homo sapiens] 84 9e-16
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 83 1e-15
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ... 81 5e-15
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [... 81 5e-15
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 80 8e-15
gi|11386183 WAS protein family, member 2 [Homo sapiens] 80 8e-15
gi|157168329 formin 1 [Homo sapiens] 78 5e-14
gi|210032580 SET domain containing 1B [Homo sapiens] 77 7e-14
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 77 9e-14
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 77 9e-14
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 77 1e-13
gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 77 1e-13
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 76 2e-13
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 76 2e-13
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 76 2e-13
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 75 3e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 4e-13
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 2161 bits (5599), Expect = 0.0
Identities = 1077/1077 (100%), Positives = 1077/1077 (100%)
Query: 1 MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP 60
MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP
Sbjct: 1 MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP 60
Query: 61 PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP 120
PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP
Sbjct: 61 PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP 120
Query: 121 PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ 180
PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ
Sbjct: 121 PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ 180
Query: 181 AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ
Sbjct: 181 AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
Query: 241 AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT 300
AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT
Sbjct: 241 AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT 300
Query: 301 TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP 360
TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP
Sbjct: 301 TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP 360
Query: 361 VMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTA 420
VMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTA
Sbjct: 361 VMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTA 420
Query: 421 DGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKE 480
DGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKE
Sbjct: 421 DGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKE 480
Query: 481 IKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDD 540
IKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDD
Sbjct: 481 IKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDD 540
Query: 541 LIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDE 600
LIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDE
Sbjct: 541 LIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDE 600
Query: 601 PVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTW 660
PVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTW
Sbjct: 601 PVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTW 660
Query: 661 EKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKF 720
EKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKF
Sbjct: 661 EKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKF 720
Query: 721 NPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFE 780
NPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFE
Sbjct: 721 NPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFE 780
Query: 781 LLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELER 840
LLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELER
Sbjct: 781 LLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELER 840
Query: 841 QARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDT 900
QARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDT
Sbjct: 841 QARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDT 900
Query: 901 RRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVK 960
RRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVK
Sbjct: 901 RRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVK 960
Query: 961 KIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESD 1020
KIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESD
Sbjct: 961 KIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESD 1020
Query: 1021 QHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK 1077
QHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK
Sbjct: 1021 QHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK 1077
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 2149 bits (5567), Expect = 0.0
Identities = 1077/1098 (98%), Positives = 1077/1098 (98%), Gaps = 21/1098 (1%)
Query: 1 MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP 60
MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP
Sbjct: 1 MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP 60
Query: 61 PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP 120
PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP
Sbjct: 61 PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP 120
Query: 121 PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ 180
PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ
Sbjct: 121 PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ 180
Query: 181 AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ
Sbjct: 181 AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
Query: 241 AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT 300
AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT
Sbjct: 241 AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT 300
Query: 301 TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP 360
TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP
Sbjct: 301 TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP 360
Query: 361 VMVPPFRVPLPGMPIPLPGV---------------------LPGMAPPIVPMIHPQVAIA 399
VMVPPFRVPLPGMPIPLPGV LPGMAPPIVPMIHPQVAIA
Sbjct: 361 VMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIA 420
Query: 400 ASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP 459
ASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP
Sbjct: 421 ASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP 480
Query: 460 SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTG 519
SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTG
Sbjct: 481 SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTG 540
Query: 520 DERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW 579
DERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW
Sbjct: 541 DERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW 600
Query: 580 QFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLE 639
QFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLE
Sbjct: 601 QFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLE 660
Query: 640 ARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERRE 699
ARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERRE
Sbjct: 661 ARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERRE 720
Query: 700 KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAA 759
KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAA
Sbjct: 721 KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAA 780
Query: 760 RKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF 819
RKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF
Sbjct: 781 RKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF 840
Query: 820 KQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI 879
KQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI
Sbjct: 841 KQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI 900
Query: 880 QNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH 939
QNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH
Sbjct: 901 QNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH 960
Query: 940 FRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFR 999
FRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFR
Sbjct: 961 FRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFR 1020
Query: 1000 TLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDR 1059
TLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDR
Sbjct: 1021 TLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDR 1080
Query: 1060 RGPPPPPTASEPTRRSTK 1077
RGPPPPPTASEPTRRSTK
Sbjct: 1081 RGPPPPPTASEPTRRSTK 1098
>gi|148727264 transcription elongation regulator 1-like [Homo
sapiens]
Length = 586
Score = 274 bits (701), Expect = 3e-73
Identities = 128/274 (46%), Positives = 188/274 (68%), Gaps = 20/274 (7%)
Query: 493 EEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQ 552
E+ A+ +PVA+ P+PG+PWCVVWTGD+RVFF+NPT LS+W++P DL R D+++II+
Sbjct: 325 EDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKPMDLKDRGDLNRIIE 384
Query: 553 EPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 612
+PPHK+ +E + + + E+ ED+ VK K+ + +
Sbjct: 385 DPPHKRKLE--------------------APATDNSDGSSSEDNREDQDVKTKRNRTEGC 424
Query: 613 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 672
E+ + + + ++PLE R+ F+DMLLERGVSAFSTWEKELHKIVFDPR
Sbjct: 425 GSPKPEEAKREDKGTRTPPPQILLPLEERVTHFRDMLLERGVSAFSTWEKELHKIVFDPR 484
Query: 673 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 732
YLLLN +ERKQ+F+Q+VKTR +EE +EKK+K++ AKE+FKK++EE+K +PR TF EFA K
Sbjct: 485 YLLLNSEERKQIFEQFVKTRIKEEYKEKKSKLLLAKEEFKKLLEESKVSPRTTFKEFAEK 544
Query: 733 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKED 766
+ +D RF+ ++K KD+E FN+F+ +K++KE+
Sbjct: 545 YGRDQRFRLVQKRKDQEHFFNQFILILKKRDKEN 578
Score = 55.1 bits (131), Expect = 4e-07
Identities = 100/460 (21%), Positives = 175/460 (38%), Gaps = 143/460 (31%)
Query: 317 VSVSTPAPTATPVQTV---PQPHPQ--------TLPPAV--------------PHSV--P 349
VS+S PAP + P+ TV PQP P T PA+ P ++ P
Sbjct: 200 VSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSVDPENLRGP 259
Query: 350 QPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPG-MAPPIVPMIHPQVAIAAS------P 402
P++ P + + P ++PL P+ G +A P M+ Q + P
Sbjct: 260 SPSSVQPRHF-LTLAPIKIPLRTSPVSDTRTERGRVARPPALMLRAQKSRDGDKEDKEPP 318
Query: 403 ATLAG-------------ATAV--SEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEK 447
L G +T V S W T D + +++N S WEKP +LK++
Sbjct: 319 PMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKPMDLKDRGD 378
Query: 448 LEEKIKEP-----IKEPSEEPLPMETEEEDPKEEPIKEIKE------EPKEEEMTEEEKA 496
L I++P ++ P+ + + E++ +++ +K + PK EE E+K
Sbjct: 379 LNRIIEDPPHKRKLEAPATDNSDGSSSEDNREDQDVKTKRNRTEGCGSPKPEEAKREDKG 438
Query: 497 AQKAKPVATAPIPGTPWCVVWTGDERVFFYNP------TTRLSMWDRPDDLIGRADVDKI 550
+ P P+ +ERV + + S W++ ++ KI
Sbjct: 439 TRTPPPQILLPL-----------EERVTHFRDMLLERGVSAFSTWEK--------ELHKI 479
Query: 551 IQEPPH-KKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKR 609
+ +P + EE K++ QF + IKEE K KK K
Sbjct: 480 VFDPRYLLLNSEERKQIFE-----------QFVKTRIKEE------------YKEKKSK- 515
Query: 610 DDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVF 669
L ++FK +L E VS +T+++ K
Sbjct: 516 ----------------------------LLLAKEEFKKLLEESKVSPRTTFKEFAEKYGR 547
Query: 670 DPRYLLLNP-KERKQVFDQYVKTRAEEERREKKNKIMQAK 708
D R+ L+ K+++ F+Q++ ++R+K+N++ K
Sbjct: 548 DQRFRLVQKRKDQEHFFNQFILIL---KKRDKENRLRLRK 584
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/205 (27%), Positives = 77/205 (37%), Gaps = 41/205 (20%)
Query: 20 RMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPF--------GMMR---GPPPPPRPPFG 68
R QQQ R R P P M PP PPPP+ G++R G PP
Sbjct: 12 RQLQQQQPRRRQPLLWP---MDAEPP---PPPPWVWMVPGSAGLLRLSAGVVVPPVLLAS 65
Query: 69 RPPFDPNMPPMPPPGGIPPPMGP--PHLQRP--PFMPPPMSSMPPP------------PG 112
PP P P +P G P P P P L P P ++ P P P
Sbjct: 66 APP--PAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPS 123
Query: 113 MMFPPGMPPVTAPGTPALPPTE------EIWVENKTPDGKVYYYNARTRESAWTKPDGVK 166
+ PP P P L P+ + W++ + P+ K+++ N+ +S W P+ +
Sbjct: 124 LGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPEESR 183
Query: 167 VIQQSELTPMLAAQAQVQAQAQAQA 191
E +LA Q V A A
Sbjct: 184 FFHGHEKPRLLANQVAVSLSRPAPA 208
Score = 41.2 bits (95), Expect = 0.005
Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 15/103 (14%)
Query: 939 HFRQLLDETSAITLTSTW-KEVKKIIKEDPRCIKFSSSDRK-------KQREFEEY--IR 988
HFR +L E ++ STW KE+ KI+ DPR + +S +RK K R EEY +
Sbjct: 456 HFRDMLLERG-VSAFSTWEKELHKIVF-DPRYLLLNSEERKQIFEQFVKTRIKEEYKEKK 513
Query: 989 DKYITAKADFRTLLKETKFITYRSKKLIQES---DQHLKDVEK 1028
K + AK +F+ LL+E+K + K E DQ + V+K
Sbjct: 514 SKLLLAKEEFKKLLEESKVSPRTTFKEFAEKYGRDQRFRLVQK 556
Score = 39.3 bits (90), Expect = 0.020
Identities = 57/283 (20%), Positives = 110/283 (38%), Gaps = 69/283 (24%)
Query: 670 DPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEF 729
D R NP V+++ + + R N+I++ +K+ A N + SE
Sbjct: 352 DDRVFFFNPTMHLSVWEKPMDLKD----RGDLNRIIEDPPHKRKLEAPATDNSDGSSSED 407
Query: 730 AAKH----AKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRG---------EKIKS 776
+ K +R + K EA ++ED TR E+ +
Sbjct: 408 NREDQDVKTKRNRTEGCGSPKPEEA------------KREDKGTRTPPPQILLPLEERVT 455
Query: 777 DFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEK 836
F ++L + + S W K K+ DPRY ++S R+ +F+Q++
Sbjct: 456 HFRDMLLERGVSAFSTWEKELHKIVFDPRYLLLNSEE-RKQIFEQFV------------- 501
Query: 837 ELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVS 896
+ RI+ +E++ ++ A+ E FK LL + S +
Sbjct: 502 ----KTRIKEEYKEKKSKLLLAKEE--------------------FKKLLEESKVSPRTT 537
Query: 897 WSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH 939
+ + +D R+ + +R+++E FN+ I L K+ +E+
Sbjct: 538 FKEFAEKYGRDQRFR--LVQKRKDQEHFFNQFILILKKRDKEN 578
>gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sapiens]
Length = 871
Score = 140 bits (353), Expect = 6e-33
Identities = 179/723 (24%), Positives = 293/723 (40%), Gaps = 126/723 (17%)
Query: 322 PAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVL 381
P P P P P LPP + Q AIP PP ++PP P+ G P PL +
Sbjct: 3 PPPFMPPPGIPPPFPPMGLPP-----MSQRPPAIPPMPPGILPPMLPPM-GAPPPLTQI- 55
Query: 382 PGMAPPIVP-MIHPQVAIAASPATLAGATAVSE-----------WTEYKTADGKTYYYNN 429
PGM PP++P M+ P V + A AT GA S W+E+ DG+ YYYN
Sbjct: 56 PGMVPPMMPGMLMPAVPVTA--ATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNA 113
Query: 430 RTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEE 489
+S WEKP LK K +L + P KE + KE K+ E
Sbjct: 114 DDKQSVWEKPSVLKSKAELLLS-QCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEV 172
Query: 490 MTEEEKAA--QKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADV 547
+ ++E A Q+ P P P P D P G V
Sbjct: 173 LVKQEAAGKQQQQLPQTLQPQPPQP---------------------QPDPPPVPPGPTPV 211
Query: 548 DKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKR 607
+ E P G E+ L P EQ ++++ E + +
Sbjct: 212 PTGLLE-PEPGGSEDCDVLEATQPL----------------EQGFLQQLEEGPSSSGQHQ 254
Query: 608 KRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKI 667
+ + + +S+ E + RE+A + FK++L ++ V + ++WE+ + +
Sbjct: 255 PQQEEE--ESKPEPERSGLSWSNREKA-------KQAFKELLRDKAVPSNASWEQAMKMV 305
Query: 668 VFDPRYLLLNPK--ERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRAT 725
V DPRY L PK E+KQ F+ Y R +EE+ E + + +AK+ + +E+ + T
Sbjct: 306 VTDPRYSAL-PKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTT 364
Query: 726 FSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSK-TRGEKIKSDFFELLSN 784
A + + A+ +DR+ ++++ + KKEKE +K R I++ L
Sbjct: 365 RYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGM 424
Query: 785 HHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYI--EKIAKNLDSEKEKELERQA 842
++ Q+ WS+ + + +P + A D D I E+ + L+ E+E+E ER
Sbjct: 425 SSVNFQTTWSQAQQYLMDNPSF-AQDHQLQNMDKEDALICFEEHIRALEREEEEERER-- 481
Query: 843 RIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVS-WSDTR 901
A LRER R+Q K EA Q F L + + +S W +
Sbjct: 482 ---ARLRER------------------RQQRKNREAFQTFLDELHETGQLHSMSTWMELY 520
Query: 902 RTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQ------LLDETSAITLTST 955
+ D R+ + LF ++E L K R H + L D + + +
Sbjct: 521 PAVSTDVRFANMLGQPGSTPLDLFKFYVEEL--KARFHDEKKIIKDILKDRGFCVEVNTA 578
Query: 956 WKEVKKIIKEDPRCIKFSSSD--------------RKKQREFEEYIRDKYITAKADFRTL 1001
+++ +I D R + + R+++RE EE R + +A FR++
Sbjct: 579 FEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMR--RREAAFRSM 636
Query: 1002 LKE 1004
L++
Sbjct: 637 LRQ 639
Score = 92.0 bits (227), Expect = 3e-18
Identities = 57/138 (41%), Positives = 68/138 (49%), Gaps = 27/138 (19%)
Query: 43 PPPLMRPP---PPFGMMRGPPPPPRPPFGRPPFDPN-MPPMPPPGGIPPPMGPPHLQRPP 98
PPP M PP PPF M PP RPP PP P +PPM PP G PPP+ Q P
Sbjct: 3 PPPFMPPPGIPPPFPPMGLPPMSQRPP-AIPPMPPGILPPMLPPMGAPPPL----TQIPG 57
Query: 99 FMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALP----------PTEEIWVENKTPDGKVY 148
+PP M PGM+ P PVTA P P +W E+ PDG++Y
Sbjct: 58 MVPPMM------PGMLMP--AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIY 109
Query: 149 YYNARTRESAWTKPDGVK 166
YYNA ++S W KP +K
Sbjct: 110 YYNADDKQSVWEKPSVLK 127
Score = 74.3 bits (181), Expect = 6e-13
Identities = 108/577 (18%), Positives = 218/577 (37%), Gaps = 107/577 (18%)
Query: 503 VATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEE 562
VA P W D R+++YN + S+W++P L +A++ ++ + P K+ +
Sbjct: 88 VAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL--LLSQCPWKEYKSD 145
Query: 563 L----------KKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 612
K+ R P L + A ++Q+ + + + +P + +
Sbjct: 146 TGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVP 205
Query: 613 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 672
+E E + + ++ ++Q LE G S+ + +
Sbjct: 206 PGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQ--------- 256
Query: 673 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 732
+E ++ + ++ REK AK+ FK+++ + A++ +
Sbjct: 257 ------QEEEESKPEPERSGLSWSNREK------AKQAFKELLRDKAVPSNASWEQAMKM 304
Query: 733 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSR 792
D R+ A+ K+ +++ FN + A K+EKE+++ R ++ K L H
Sbjct: 305 VVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQH------- 357
Query: 793 WSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLRERE 852
+++ S RY+ + + +++ E+ K + + + L ++E
Sbjct: 358 -----ERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD----------VLFFLAKKE 402
Query: 853 REVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTLRKDHRWE 911
+ EQ K++ R IQ K++L M + +WS ++ L + +
Sbjct: 403 K-------EQAKQL--------RRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFA 447
Query: 912 SGSLLEREEKEK---LFNEHIEAL------------------TKKKREHFRQLLD---ET 947
L+ +KE F EHI AL +K RE F+ LD ET
Sbjct: 448 QDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHET 507
Query: 948 SAITLTSTWKEVKKIIKEDPRCIKF----SSSDRKKQREFEEYIRDKYITAKADFRTLLK 1003
+ STW E+ + D R S+ + + E ++ ++ K + +LK
Sbjct: 508 GQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILK 567
Query: 1004 ETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLD 1040
+ F E + +D ++ DKR LD
Sbjct: 568 DRGFCV--------EVNTAFEDFAHVISFDKRAAALD 596
Score = 55.1 bits (131), Expect = 4e-07
Identities = 112/538 (20%), Positives = 207/538 (38%), Gaps = 87/538 (16%)
Query: 334 QPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPG------VLPGMAP 386
Q PQTL P P P P PPV PP P+P G+ P PG VL P
Sbjct: 184 QQLPQTLQPQPPQPQPDP-------PPV--PPGPTPVPTGLLEPEPGGSEDCDVLEATQP 234
Query: 387 PIVPMIHPQVAIAASPATLAGATAVSEWTEYKTA---DGKTYYYNNRTLESTWE--KPQE 441
+ + P++ E E K G ++ + ++ E + +
Sbjct: 235 LEQGFLQQ---LEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKA 291
Query: 442 LKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAK 501
+ E+ +K + +P LP +E K++ K + ++EE E A++AK
Sbjct: 292 VPSNASWEQAMKMVVTDPRYSALPKLSE----KKQAFNAYKAQREKEEKEEARLRAKEAK 347
Query: 502 PVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHK---- 557
T + + T + + R + G +V ++ E K
Sbjct: 348 Q---------------TLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYD 392
Query: 558 --------KGMEELKKLRHPTPTMLS-----IQKWQFSMSAIKEEQELMEEINEDEPVKA 604
K E+ K+LR L + F + + +Q LM+ + + +
Sbjct: 393 DVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQL 452
Query: 605 KKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQ-------FKDMLLERG-VSA 656
+ ++D E A+E E + RERA + + ++ F D L E G + +
Sbjct: 453 QNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHS 512
Query: 657 FSTWEKELHKIVFDPRY--LLLNPKERK-QVFDQYVKTRAEEERREKKNKIMQAKEDFKK 713
STW + + D R+ +L P +F YV+ E K + K+ K
Sbjct: 513 MSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVE--------ELKARFHDEKKIIKD 564
Query: 714 MMEEAKF--NPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFV--AAARKKEKEDSKT 769
++++ F F +FA + D R A++ + + FN + A AR++E+E +
Sbjct: 565 ILKDRGFCVEVNTAFEDFAHVISFDKRAAALDA-GNIKLTFNSLLEKAEAREREREKEEA 623
Query: 770 RGEKIKSDFFELLSNHH---LDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIE 824
R + + F + L+ + W +V+++ D ++ + S R LF+++++
Sbjct: 624 RRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQ 681
Score = 47.4 bits (111), Expect = 7e-05
Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
Query: 643 KQFKDMLLERG--VSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYV-KTRAEEERRE 699
K KD+L +RG V + +E H I FD R L+ K F+ + K A E RE
Sbjct: 560 KIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEARERERE 619
Query: 700 KKN--KIMQAKEDFKKMMEEA--KFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEF 755
K+ ++ + + F+ M+ +A + E + DS F+ I +R LF EF
Sbjct: 620 KEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREF 679
Query: 756 VAAARKKEKEDSKTRGEK 773
+ + E + T+G K
Sbjct: 680 LQVLEQTECQHLHTKGRK 697
>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sapiens]
Length = 858
Score = 139 bits (351), Expect = 1e-32
Identities = 173/707 (24%), Positives = 290/707 (41%), Gaps = 119/707 (16%)
Query: 335 PHPQTLPPAVPHSVP---QPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVP- 390
P P PP P +P Q AIP PP ++PP P+ G P PL + PGM PP++P
Sbjct: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPM-GAPPPLTQI-PGMVPPMMPG 59
Query: 391 MIHPQVAIAASPATLAGATAVSE-----------WTEYKTADGKTYYYNNRTLESTWEKP 439
M+ P V + A AT GA S W+E+ DG+ YYYN +S WEKP
Sbjct: 60 MLMPAVPVTA--ATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKP 117
Query: 440 QELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAA-- 497
LK K +L + P KE + KE K+ E + ++E A
Sbjct: 118 SVLKSKAELLLS-QCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQ 176
Query: 498 QKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHK 557
Q+ P P P P D P G V + E P
Sbjct: 177 QQQLPQTLQPQPPQP---------------------QPDPPPVPPGPTPVPTGLLE-PEP 214
Query: 558 KGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDS 617
G E+ L P EQ ++++ E + + + + + +S
Sbjct: 215 GGSEDCDVLEATQPL----------------EQGFLQQLEEGPSSSGQHQPQQEEE--ES 256
Query: 618 EKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLN 677
+ E + RE+A + FK++L ++ V + ++WE+ + +V DPRY L
Sbjct: 257 KPEPERSGLSWSNREKA-------KQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSAL- 308
Query: 678 PK--ERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAK 735
PK E+KQ F+ Y R +EE+ E + + +AK+ + +E+ + T A +
Sbjct: 309 PKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFG 368
Query: 736 DSRFKAIEKMKDREALFNEFVAAARKKEKEDSK-TRGEKIKSDFFELLSNHHLDSQSRWS 794
+ A+ +DR+ ++++ + KKEKE +K R I++ L ++ Q+ WS
Sbjct: 369 ELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWS 428
Query: 795 KVKDKVESDPRYKAVDSSSMREDLFKQYI--EKIAKNLDSEKEKELERQARIEASLRERE 852
+ + + +P + A D D I E+ + L+ E+E+E ER A LRER
Sbjct: 429 QAQQYLMDNPSF-AQDHQLQNMDKEDALICFEEHIRALEREEEEERER-----ARLRER- 481
Query: 853 REVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVS-WSDTRRTLRKDHRWE 911
R+Q K EA Q F L + + +S W + + D R+
Sbjct: 482 -----------------RQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFA 524
Query: 912 SGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIK 971
+ LF ++E L + + + + D + + + +++ +I D R
Sbjct: 525 NMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKD---ILKVNTAFEDFAHVISFDKRAAA 581
Query: 972 FSSSD--------------RKKQREFEEYIRDKYITAKADFRTLLKE 1004
+ + R+++RE EE R + +A FR++L++
Sbjct: 582 LDAGNIKLTFNSLLEKAEAREREREKEEARRMR--RREAAFRSMLRQ 626
Score = 87.4 bits (215), Expect = 6e-17
Identities = 55/135 (40%), Positives = 67/135 (49%), Gaps = 26/135 (19%)
Query: 43 PPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPN-MPPMPPPGGIPPPMGPPHLQRPPFMP 101
PPP + PPPF M PP RPP PP P +PPM PP G PPP+ Q P +P
Sbjct: 2 PPPGI--PPPFPPMGLPPMSQRPP-AIPPMPPGILPPMLPPMGAPPPL----TQIPGMVP 54
Query: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPALP----------PTEEIWVENKTPDGKVYYYN 151
P M PGM+ P PVTA P P +W E+ PDG++YYYN
Sbjct: 55 PMM------PGMLMP--AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYN 106
Query: 152 ARTRESAWTKPDGVK 166
A ++S W KP +K
Sbjct: 107 ADDKQSVWEKPSVLK 121
Score = 73.2 bits (178), Expect = 1e-12
Identities = 109/576 (18%), Positives = 217/576 (37%), Gaps = 112/576 (19%)
Query: 503 VATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEE 562
VA P W D R+++YN + S+W++P L +A++ ++ + P K+ +
Sbjct: 82 VAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL--LLSQCPWKEYKSD 139
Query: 563 L----------KKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 612
K+ R P L + A ++Q+ + + + +P + +
Sbjct: 140 TGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVP 199
Query: 613 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 672
+E E + + ++ ++Q LE G S+ + +
Sbjct: 200 PGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQ--------- 250
Query: 673 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 732
+E ++ + ++ REK AK+ FK+++ + A++ +
Sbjct: 251 ------QEEEESKPEPERSGLSWSNREK------AKQAFKELLRDKAVPSNASWEQAMKM 298
Query: 733 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSR 792
D R+ A+ K+ +++ FN + A K+EKE+++ R ++ K L H
Sbjct: 299 VVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQH------- 351
Query: 793 WSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLRERE 852
+++ S RY+ + + +++ E+ K + + + L ++E
Sbjct: 352 -----ERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD----------VLFFLAKKE 396
Query: 853 REVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTLRKDHRWE 911
+ EQ K++ R IQ K++L M + +WS ++ L + +
Sbjct: 397 K-------EQAKQL--------RRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFA 441
Query: 912 SGSLLEREEKEK---LFNEHIEAL------------------TKKKREHFRQLLD---ET 947
L+ +KE F EHI AL +K RE F+ LD ET
Sbjct: 442 QDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHET 501
Query: 948 SAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKF 1007
+ STW E+ + D R F + T F+ ++E K
Sbjct: 502 GQLHSMSTWMELYPAVSTDVR--------------FANMLGQPGSTPLDLFKFYVEELKA 547
Query: 1008 ITYRSKKLIQE---SDQHLKDVEKILQNDKRYLVLD 1040
+ KK+I++ + +D ++ DKR LD
Sbjct: 548 RFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALD 583
Score = 72.4 bits (176), Expect = 2e-12
Identities = 55/173 (31%), Positives = 69/173 (39%), Gaps = 63/173 (36%)
Query: 59 PP--PPPRPPFGRPPFD---PNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGM 113
PP PPP PP G PP P +PPMPP GI PPM PP PP P P PGM
Sbjct: 3 PPGIPPPFPPMGLPPMSQRPPAIPPMPP--GILPPMLPPMGAPPPLTQIPGMVPPMMPGM 60
Query: 114 MFPPGMPPVTAPGTPALP----------PTEEIWVENKTPDGKVYYYNA----------- 152
+ P PVTA P P +W E+ PDG++YYYNA
Sbjct: 61 LMPA--VPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPS 118
Query: 153 ------------------------------RTRESAWTKP---DGVKVIQQSE 172
+++ES WT+P D ++V+ + E
Sbjct: 119 VLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQE 171
Score = 55.5 bits (132), Expect = 3e-07
Identities = 113/538 (21%), Positives = 213/538 (39%), Gaps = 94/538 (17%)
Query: 334 QPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPG------VLPGMAP 386
Q PQTL P P P P PPV PP P+P G+ P PG VL P
Sbjct: 178 QQLPQTLQPQPPQPQPDP-------PPV--PPGPTPVPTGLLEPEPGGSEDCDVLEATQP 228
Query: 387 PIVPMIHPQVAIAASPATLAGATAVSEWTEYKTA---DGKTYYYNNRTLESTWE--KPQE 441
+ + P++ E E K G ++ + ++ E + +
Sbjct: 229 LEQGFLQQ---LEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKA 285
Query: 442 LKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAK 501
+ E+ +K + +P LP +E K++ K + ++EE E A++AK
Sbjct: 286 VPSNASWEQAMKMVVTDPRYSALPKLSE----KKQAFNAYKAQREKEEKEEARLRAKEAK 341
Query: 502 PVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHK---- 557
T + + T + + R + G +V ++ E K
Sbjct: 342 Q---------------TLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYD 386
Query: 558 --------KGMEELKKLRHPTPTMLS-----IQKWQFSMSAIKEEQELMEEINEDEPVKA 604
K E+ K+LR L + F + + +Q LM+ + + +
Sbjct: 387 DVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQL 446
Query: 605 KKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQ-------FKDMLLERG-VSA 656
+ ++D E A+E E + RERA + + ++ F D L E G + +
Sbjct: 447 QNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHS 506
Query: 657 FSTWEKELHKIVFDPRYLLL------NPKERKQVFDQYVKTRAEEERREKKN--KIMQAK 708
STW + + D R+ + P + + + + +K R +E++ K+ K+ A
Sbjct: 507 MSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKVNTAF 566
Query: 709 EDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSK 768
EDF ++ F+ RA + A + K + +EK + RE R++EKE+++
Sbjct: 567 EDFAHVIS---FDKRAAALD--AGNIKLTFNSLLEKAEARE----------REREKEEAR 611
Query: 769 TRGEKIKSDFFELLSNH--HLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIE 824
R + ++ F +L L+ + W +V+++ D ++ + S R LF+++++
Sbjct: 612 -RMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQ 668
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 130 bits (328), Expect = 5e-30
Identities = 176/753 (23%), Positives = 305/753 (40%), Gaps = 125/753 (16%)
Query: 322 PAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPG-MPIPLPGV 380
P P+ P +PP VPH + P M+PP P G MP + V
Sbjct: 32 PGMHYAPMGMHPMGQRANMPP-VPHGMM----------PQMMPPMGGPPMGQMPGMMSSV 80
Query: 381 LPGMA------PPIVPMIHPQV-AIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLE 433
+PGM + P + P V ++ + T +GA ++ WTE+K+ DG+TYYYN T +
Sbjct: 81 MPGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSM--WTEHKSPDGRTYYYNTETKQ 138
Query: 434 STWEKPQELKEK-EKLEEKIK-EPIKEPSEEPLPMETEEEDPKEEPIKEIKEEP------ 485
STWEKP +LK E+L K + K S +P ++ ++ + KE+++
Sbjct: 139 STWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTI 198
Query: 486 ----------------KEEEMTEEEKAAQKAKPVATAPIPGT---------PWCVVWTGD 520
EE +EE PV T IP T VV
Sbjct: 199 VAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAA 258
Query: 521 ERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQ 580
+ + + G V + EP + + + T T+ + ++ Q
Sbjct: 259 AAAAAAAAANANASTSASNTVSGTVPV---VPEPEVTSIVATVVDNEN-TVTISTEEQAQ 314
Query: 581 FSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEA 640
+ + ++Q + N E K++ D +KE E E + A++ +
Sbjct: 315 LTSTPAIQDQSVEVSSNTGEETS----KQETVADFTPKKE---EEESQPAKKTYTWNTKE 367
Query: 641 RMKQ-FKDMLLERGVSAFSTWEKELHKIVFDPRY-LLLNPKERKQVFDQYVKTRAEEERR 698
KQ FK++L E+ V + ++WE+ + I+ DPRY L E+KQ F+ Y +EE+
Sbjct: 368 EAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKE 427
Query: 699 EKKNKIMQAKEDFKKMME-EAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVA 757
E ++K +AKE F++ +E K + + + + AI + +DR ++ + +
Sbjct: 428 EARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISE-RDRLEIYEDVLF 486
Query: 758 AARKKEKEDSKTRGEKIKSDFFELLSN-HHLDSQSRWSKVKDKVESDPRYKAVDSSSMRE 816
KKEKE +K ++ +L N ++ + WS+ + + +P + A D
Sbjct: 487 FLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTF-AEDEELQNM 545
Query: 817 D------LFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDRER 870
D F+++I + K + EK+K L LRER R
Sbjct: 546 DKEDALICFEEHIRALEKEEEEEKQKSL---------LRER------------------R 578
Query: 871 EQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHI 929
Q K E+ Q F L + + S SW + T+ D R+ + LF ++
Sbjct: 579 RQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYV 638
Query: 930 EALTKKKREHFRQ------LLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRK----- 978
E L K R H + L D+ + + +T+++ II R + + K
Sbjct: 639 EDL--KARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNS 696
Query: 979 -------KQREFEEYIRDKYITAKADFRTLLKE 1004
++RE E+ K ++ F+++LK+
Sbjct: 697 LLEKAEAREREREKEEARKMKRKESAFKSMLKQ 729
Score = 121 bits (304), Expect = 3e-27
Identities = 187/947 (19%), Positives = 348/947 (36%), Gaps = 156/947 (16%)
Query: 45 PLMRPPPPF---GMMRGPPPPPRPPFGRPPFDP--NMPPMPP---PGGIPPPMGPPHLQR 96
P MRP G+M G P P G P NMPP+P P +PP GPP Q
Sbjct: 14 PTMRPGTGAERGGLMMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPPMGGPPMGQM 73
Query: 97 PPFMPPPMSSMPPPPGMMFP----PGMPPVTAPGTPALPPT-------EEIWVENKTPDG 145
P M M PGMM M P PG ++ + +W E+K+PDG
Sbjct: 74 PGMMSSVM------PGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDG 127
Query: 146 KVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQA 205
+ YYYN T++S W KPD +K + L+ + + + +Q + A+ +
Sbjct: 128 RTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKE 187
Query: 206 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSS 265
+ ++ A +A+ ++ + T T+++
Sbjct: 188 LEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEE-----------------CTTTSTA 230
Query: 266 PAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPT 325
P P T+ ST ++ + + A ++A + A S S
Sbjct: 231 PVPTTEIPTTMSTMAAAEAAAAVVAAAAAA-----------AAAAAAANANASTSASNTV 279
Query: 326 ATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMA 385
+ V VP+P ++ V + + T I + P +
Sbjct: 280 SGTVPVVPEPEVTSIVATVVDN--ENTVTISTEEQAQLTS---------------TPAIQ 322
Query: 386 PPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKE- 444
V + + T+A T E E + A KTY TW +E K+
Sbjct: 323 DQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAK-KTY---------TWNTKEEAKQA 372
Query: 445 -KEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPK-------EEEMTEEEKA 496
KE L+EK + P E+ + M DP+ + ++ E+ + + E E+E+A
Sbjct: 373 FKELLKEK-RVPSNASWEQAMKMIIN--DPRYSALAKLSEKKQAFNAYKVQTEKEEKEEA 429
Query: 497 AQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPH 556
K K + + + T + + + + + G +V I E
Sbjct: 430 RSKYKEAKES------------FQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDR 477
Query: 557 ------------KKGMEELKKLRHP-----------------TPTMLSIQKWQFSMSAIK 587
KK E+ K+LR + T Q++
Sbjct: 478 LEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFA 537
Query: 588 EEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKD 647
E++EL ED + ++ R K+ + EK+ ++ E + R+ + F D
Sbjct: 538 EDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKN-----RESFQIFLD 592
Query: 648 MLLERG-VSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQ 706
L E G + + S+W + I D R+ + + D + K E+ K +
Sbjct: 593 ELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLF-KFYVED----LKARYHD 647
Query: 707 AKEDFKKMMEEAKF--NPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFV--AAARKK 762
K+ K ++++ F TF +F A + R ++ + A FN + A AR++
Sbjct: 648 EKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLA-FNSLLEKAEARER 706
Query: 763 EKEDSKTRGEKIKSDFFELLSNHH---LDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF 819
E+E + R K K F+ + ++ + W ++++ +P ++ + S R+ +F
Sbjct: 707 EREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIF 766
Query: 820 KQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI 879
K ++ + K + + + R+R R + S+ +++ Q +
Sbjct: 767 KDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSA 826
Query: 880 QNFKALLSDMVRSSDVSWSDTRRTLRKDHRW---ESGSLLEREEKEK 923
+ ++ RS S +++ ++ H+ ES + E+++KEK
Sbjct: 827 SEHSS-SAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEK 872
Score = 80.9 bits (198), Expect = 6e-15
Identities = 90/393 (22%), Positives = 166/393 (42%), Gaps = 76/393 (19%)
Query: 680 ERKQVFDQYVKTRAEEERREKK----NKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAK 735
+++ V D K EE + KK N +AK+ FK++++E + A++ +
Sbjct: 338 KQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN 397
Query: 736 DSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSK 795
D R+ A+ K+ +++ FN + K+EKE+++++ ++ K F L NH
Sbjct: 398 DPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENH---------- 447
Query: 796 VKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREV 855
+K+ S RYK + + + E N SE+++ LE + L ++E+
Sbjct: 448 --EKMTSTTRYKKAE---------QMFGEMEVWNAISERDR-LEIYEDVLFFLSKKEK-- 493
Query: 856 QKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSL 915
EQ K++ + + EA++N ++++ S+ +WS+ ++ L + +
Sbjct: 494 -----EQAKQL-----RKRNWEALKNILDNMANVTYST--TWSEAQQYLMDNPTFAEDEE 541
Query: 916 LEREEKEK---LFNEHIEALTK------------------KKREHFRQLLDET---SAIT 951
L+ +KE F EHI AL K K RE F+ LDE +
Sbjct: 542 LQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLH 601
Query: 952 LTSTWKEVKKIIKEDPRCIKFSSSDRKKQRE-FEEYIRD---KYITAKADFRTLLKETKF 1007
S+W E+ I D R + F+ Y+ D +Y K + +LK+ F
Sbjct: 602 SMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGF 661
Query: 1008 ITYRSKKLIQESDQHLKDVEKILQNDKRYLVLD 1040
+ E + +D I+ + KR LD
Sbjct: 662 VV--------EVNTTFEDFVAIISSTKRSTTLD 686
Score = 80.5 bits (197), Expect = 8e-15
Identities = 156/729 (21%), Positives = 275/729 (37%), Gaps = 125/729 (17%)
Query: 414 WTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDP 473
W EYK+ GK YYYN++T ES W KP+EL++ E + I M EE
Sbjct: 160 WKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESS 219
Query: 474 KEEPIKEIKEEP---KEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTT 530
K+E P E T AA +A A + T
Sbjct: 220 KQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTV 279
Query: 531 RLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKE-- 588
++ P+ + + E EE +L TP + Q + S + +E
Sbjct: 280 SGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTS-TPAIQD-QSVEVSSNTGEETS 337
Query: 589 EQELM------EEINEDEPVK------AKKRKRDDNKDIDSEK--------EAAMEAEIK 628
+QE + +E E +P K K+ + K++ EK E AM+ I
Sbjct: 338 KQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN 397
Query: 629 AARERAIVPLEARMKQFKDMLLE--------------RGVSAFSTWEKELHKIVFDPRYL 674
R A+ L + + F ++ +F + + K+ RY
Sbjct: 398 DPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYK 457
Query: 675 -------------LLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEE-AKF 720
++ ++R ++++ + +++E+ + K + E K +++ A
Sbjct: 458 KAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANV 517
Query: 721 NPRATFSEFAAKHAKDSRFKA----IEKMKDREAL--FNEFVAAARKKEKEDS------- 767
T+SE A ++ D+ A ++ M +AL F E + A K+E+E+
Sbjct: 518 TYSTTWSE-AQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRE 576
Query: 768 KTRGEKIKSDFFELLSNHH----LDSQSRWSKVKDKVESDPRYKAV--DSSSMREDLFKQ 821
+ R K + F L H L S S W ++ + SD R+ + S DLFK
Sbjct: 577 RRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKF 636
Query: 822 YIE----------KIAKNLDSEKEKELERQARIE---ASLRERERE-------------- 854
Y+E KI K++ +K +E E A + +R
Sbjct: 637 YVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNS 696
Query: 855 -VQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR--SSDVSWSDTRRTLRKDHRWE 911
++KA + + + E + KR+E+ FK++L D W D R K+ +E
Sbjct: 697 LLEKAEAREREREKEEARKMKRKESA--FKSMLKQAAPPIELDAVWEDIRERFVKEPAFE 754
Query: 912 SGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIK 971
+L E++++F + + L + + H + + K+ KK ++ R
Sbjct: 755 DITL--ESERKRIFKDFMHVLEHECQHHHSKNKKHS---------KKSKKHHRKRSRSRS 803
Query: 972 FSSSD-----RKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDV 1026
S SD KK+R+ E ++ A+ K++K +SKK +SD D
Sbjct: 804 GSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDA 863
Query: 1027 EKILQNDKR 1035
E+ + DK+
Sbjct: 864 ER--EKDKK 870
Score = 57.0 bits (136), Expect = 9e-08
Identities = 72/301 (23%), Positives = 122/301 (40%), Gaps = 35/301 (11%)
Query: 643 KQFKDMLLERG--VSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYV-KTRAEEERRE 699
K KD+L ++G V +T+E + I R L+ K F+ + K A E RE
Sbjct: 650 KIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEARERERE 709
Query: 700 KKN--KIMQAKEDFKKMMEEAK--FNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEF 755
K+ K+ + + FK M+++A A + + + K+ F+ I +R+ +F +F
Sbjct: 710 KEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDF 769
Query: 756 VAAARKK-EKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAV--DSS 812
+ + + SK + KS +H S+SR D +S + K +S
Sbjct: 770 MHVLEHECQHHHSKNKKHSKKSK-----KHHRKRSRSRSGSDSDDDDSHSKKKRQRSESR 824
Query: 813 SMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQ 872
S E E+ K K+K +R+ + ++ + ERE K ++ E DR R+
Sbjct: 825 SASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQ- 883
Query: 873 HKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWE-SGSLLEREEKEKLFNEHIEA 931
RS S ++T + W+ SGS L E EK +E
Sbjct: 884 ------------------RSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQ 925
Query: 932 L 932
L
Sbjct: 926 L 926
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 99.4 bits (246), Expect = 2e-20
Identities = 130/626 (20%), Positives = 283/626 (45%), Gaps = 104/626 (16%)
Query: 437 EKPQELKEKEKLEEKIKEPIK----EPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTE 492
E+ Q+L + E+ EE+ ++ ++ E E+ L E EEE ++ +E +EE +E+E+ E
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 493 EEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQ 552
EE+ ++A+ + IP W + D R + ++ RP Q
Sbjct: 688 EEQ--EQARERIKSRIPKWQWQLESEADAR--------QSKVYSRPRK-----------Q 726
Query: 553 EPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINED--------EPVKA 604
E ++ +E K+ R S +WQ A +++QE EE D E +
Sbjct: 727 EGQRRRQEQEEKRRRRE-----SELQWQEEERAHRQQQE--EEQRRDFTWQWQAEEKSER 779
Query: 605 KKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKEL 664
+++ + ++E + AE + RE+ +P E +Q + ER EKEL
Sbjct: 780 GRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER--------EKEL 831
Query: 665 HKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRA 724
+ + + L +ER Q Q + +E++ ++++ + + ++ +EE + R
Sbjct: 832 QFLEEEEQ---LQRRERAQQL-QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Query: 725 TFSEFAAKHAKDSRFKAIEKM--KDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELL 782
T AK A + + +++ ++ E L E R++E+E E+++ + +LL
Sbjct: 888 T---LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 783 SNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQA 842
+ + + E + +Y+ +E+ + + + + + +E E++
Sbjct: 945 REER--------EKRRRQERERQYRKDKKLQQKEE------QLLGEEPEKRRRQEREKKY 990
Query: 843 RIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRR 902
R E L++ E ++ + E+ + + ER+ K++E Q + LL + + RR
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE--------REKRR 1042
Query: 903 TLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKI 962
++ ++ L++EE E+L E E T++++E RQ E +E +++
Sbjct: 1043 LQERERQYREEEELQQEE-EQLLGEERE--TRRRQELERQYRKE------EELQQEEEQL 1093
Query: 963 IKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQH 1022
++E+P ++++++E E R++ + + + L +E R K+ QE ++
Sbjct: 1094 LREEP--------EKRRRQERERQCREEEELQQEEEQLLREE------REKRRRQELERQ 1139
Query: 1023 LKDVEKILQNDKRYLVLDCVPEERRK 1048
++ E++ Q +++ L + PE+RR+
Sbjct: 1140 YREEEEVQQEEEQLLREE--PEKRRR 1163
Score = 79.7 bits (195), Expect = 1e-14
Identities = 122/632 (19%), Positives = 277/632 (43%), Gaps = 77/632 (12%)
Query: 427 YNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPK 486
Y L+ K Q+L ++E+ E + +E K +E EEE ++E + ++EE +
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 487 EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRAD 546
+ E E+ +K K + +E++ P R R + +
Sbjct: 950 KRRRQERERQYRKDKKLQQK-------------EEQLLGEEPEKR-----RRQEREKKYR 991
Query: 547 VDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSM----SAIKEEQELMEEINEDEPV 602
++ +Q+ + EE +K R Q+W+ +EE++L+ E E +
Sbjct: 992 EEEELQQEEEQLLREEREKRRR--------QEWERQYRKKDELQQEEEQLLREEREKRRL 1043
Query: 603 KAKKRKRDDNKDIDSEKEAAMEAEIKAARERAI---VPLEARMKQFKDMLLERGVSAFST 659
+ ++R+ + +++ E+E + E + R + + E ++Q ++ LL
Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR 1103
Query: 660 WEKEL-----HKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKM 714
E+E ++ + LL +E+++ + + R EEE ++++ ++++ + + ++
Sbjct: 1104 QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR 1163
Query: 715 ME-EAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEK 773
E E ++ + + ++ + K + ++RE + E R+K K+ + R E
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEK---RRQERERQYREEEELQRQKRKQ--RYRDED 1218
Query: 774 IKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSE 833
+SD + ++ R +KV K + +++ ++ S +R+ +Q ++ + L +
Sbjct: 1219 QRSD-LKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHL---LGEQ 1274
Query: 834 KEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSS 893
+E++ E++ R ++R+R + E+ E + ++E +R+ Q K LL + R
Sbjct: 1275 QERDREQERR---RWQQRDRHFPE---EEQLEREEQKEAKRRDRKSQEEKQLLRE-EREE 1327
Query: 894 DVSWSDTRRTLRKDHRW---ESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAI 950
+T R R++ + L R+E+++ F E + +E R+ L+E +
Sbjct: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE----ELRHQEQGRKFLEEEQRL 1383
Query: 951 TLTSTWKEVKKIIKEDP--RCIKFSSS-----DRKKQREFEEYIRD----KYITAKADFR 999
+ +K +KE+ RC + DRK + E ++ R K+ + R
Sbjct: 1384 ---RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR 1440
Query: 1000 TLLKETKFITYRSKKLIQESDQHLKDVEKILQ 1031
+E KF+ ++L QE + ++ E++LQ
Sbjct: 1441 RQERERKFLE-EEQQLRQERHRKFREEEQLLQ 1471
Score = 75.9 bits (185), Expect = 2e-13
Identities = 105/609 (17%), Positives = 265/609 (43%), Gaps = 36/609 (5%)
Query: 443 KEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKP 502
+++E+ E++++ +E E+ L E EEE +++ +E +EE +E+++ E++ ++ +
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 503 VATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEE 562
+ ++++ R R L + ++ Q+ ++ +
Sbjct: 390 RREQQLRREQQL---RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Query: 563 LKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAA 622
LK+ + L ++ + +Q+L + E+ + K + ++ ++ +E
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
Query: 623 MEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERK 682
+ E + RE+ + + ++ ++ L +R S E++L + + R LL +E K
Sbjct: 507 LRREQEERREQRL-----KRQEEEERLQQRLRS-----EQQLRREQEERREQLLKREEEK 556
Query: 683 QVFDQYVKTRAEEERREKKNKIMQAKEDFK----KMMEEAKFNPRATFSEFAAKHAKDSR 738
++ + + R + E+ E+++++++ +E+ + K +E + R E ++ R
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Query: 739 FKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKD 798
+ +++ + E + + + ++E+ + R E+ + L + + K +
Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH 676
Query: 799 KVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSE----KEKELERQARIEASLRERERE 854
+ E + A + + K I K L+SE + K R + E R +E+E
Sbjct: 677 EEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQE 736
Query: 855 VQKARSE---QTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWE 911
++ R E Q +E +R Q + EE ++F +S + R ++ R
Sbjct: 737 EKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER 796
Query: 912 SGSLLEREEKEKLF---NEHIEALTKKKREHFRQL--LDETSAITLTSTWKEVKKIIKED 966
ER+++E+ F E E +++RE ++L L+E + +++++ +ED
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE--EED 854
Query: 967 PRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDV 1026
D++++R E+ K+ + R + T + ++ +++ Q L++
Sbjct: 855 G-----LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Query: 1027 EKILQNDKR 1035
E+ LQ ++R
Sbjct: 910 EEELQREER 918
Score = 72.8 bits (177), Expect = 2e-12
Identities = 104/544 (19%), Positives = 239/544 (43%), Gaps = 83/544 (15%)
Query: 437 EKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPK-EEPIKEIKEEPKEEEMTEEEK 495
++ Q+L+ +E+ ++ ++ ++ EE + +E D K E ++++ + +E + EEE+
Sbjct: 1394 KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Query: 496 AAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVD-KIIQEP 554
++ ER + +L + +R + + R + D K ++E
Sbjct: 1454 QLRQ---------------------ERHRKFREEEQL-LQEREEQQLHRQERDRKFLEEE 1491
Query: 555 PHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINE----DEPVKAKKRKRD 610
+ E +K R ++ + ++EEQ+L + + E + ++++R
Sbjct: 1492 QQLRRQERDRKFREQ-----ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERG 1546
Query: 611 DNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFD 670
+ D +++ E +++ RE + + R ++F+ L E+ V +++ K + D
Sbjct: 1547 QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR--LEEQKVRR----QEQERKFMED 1600
Query: 671 PRYLLLNPKERKQVFDQYVKTRAEEER-REKKNKIMQAKEDFKKMMEEAKFNPRATFSEF 729
+ L +++ ++ K R +E+ +E++ + + +E +K +EE R E
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP-QLRRQEREQ 1659
Query: 730 AAKHAKDSRFKAIEKM-----------KDREALFNEFVAAARKKEKE------DSKTRGE 772
+H +D +F+ E++ ++R+ F E R++E+E + + R +
Sbjct: 1660 QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQ 1719
Query: 773 KIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRY-KAVDSSSMREDLFKQYIEKIAKNLD 831
+++ F E + Q R ++++ RY K ++ +R + +Q + + ++
Sbjct: 1720 ELERKFRE-------EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Query: 832 SEKEKELERQARIEASLRERE-----REVQKARSEQTKEIDR----------EREQHKRE 876
+E++L RQ R E LR +E RE ++ R E+ ++ R E EQ + E
Sbjct: 1773 FREEEQL-RQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Query: 877 EAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKE-KLFNEHIEALTKK 935
E Q + R+ + + + + W+ R+E+E KL EHI K+
Sbjct: 1832 EQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Query: 936 KREH 939
++ H
Sbjct: 1892 EQRH 1895
Score = 70.1 bits (170), Expect = 1e-11
Identities = 116/589 (19%), Positives = 237/589 (40%), Gaps = 74/589 (12%)
Query: 421 DGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKE 480
D + + +R LE E Q ++K + +E+ +E SE+ +E + ++E +
Sbjct: 118 DQRRFEPRDRQLEE--EPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
Query: 481 IKEEPKE-EEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPD 539
++E +E EE EE+ Q K T P DE L R +
Sbjct: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFP----------DEEQLRRRELLELRRKGREE 225
Query: 540 DLIGRAD-VDKIIQEPPHKKGME-------ELKKLRHPTPTMLSIQKWQFSMSAIKEEQE 591
R + D++ QE K+ + E +KL+ P + + E QE
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQE 285
Query: 592 LMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLE 651
L E E+E + + R+ + E+ + E + +ER E R +Q + E
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345
Query: 652 RGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDF 711
R R L ++ ++ +Q ++ EEERRE++ + Q
Sbjct: 346 R-------------------REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 712 KKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRG 771
+++ E + R + ++ + + ++++ + L E R ++K + + R
Sbjct: 387 QQLRREQQLR-REQQLRREQQLRREQQLRREQQLRREQQLRRE-QEEERHEQKHEQERRE 444
Query: 772 EKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLD 831
+++K + + + W K +++ E + + ++ D Q E+ + L
Sbjct: 445 QRLKRE---------QEERRDWLKREEETERHEQERR--KQQLKRD---QEEERRERWLK 490
Query: 832 SEKEKELERQARIEASLREREREVQKARSEQTKEIDR-----EREQHKREEAIQNFKALL 886
E+E+ E+Q R E LR + E ++ R ++ +E +R EQ R E + + LL
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 887 SDMVRSSDVSWSDTRR--TLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLL 944
R + RR L+++ LL+REE+ + + L +++ E Q L
Sbjct: 551 K---REEEKRLEQERREQRLKREQEERRDQLLKREEERRQ-----QRLKREQEERLEQRL 602
Query: 945 DETSAITLTSTWKEVKKIIKEDP---RCIKFSSSDRKKQREFEEYIRDK 990
L + +++ +E+P R + S+ +++R ++ R++
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ 651
Score = 60.8 bits (146), Expect = 6e-09
Identities = 94/483 (19%), Positives = 207/483 (42%), Gaps = 70/483 (14%)
Query: 598 EDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAF 657
E+EP + +++KR + E+E A E +ER LE R +Q +D L R
Sbjct: 130 EEEPGQRRRQKRQEQ-----ERELAEGEEQSEKQER----LEQRDRQRRDEELWR---QR 177
Query: 658 STWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAE-------------EERREKKNKI 704
W++ + + + E ++ D+ R E ++RRE+++++
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Query: 705 MQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEK 764
Q +E E ++ R T + ++ + ++++ E + ++E+
Sbjct: 238 FQEEE-------EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290
Query: 765 EDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIE 824
++ + + ++++ R +++ K E + R + + +E +Q E
Sbjct: 291 QEEEQQQQRLR----------------REQQLRRKQEEERREQQEERREQQERR-EQQEE 333
Query: 825 KIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQH-KREEAIQNFK 883
+ + L E+E+ E+Q R E RE+++++ + E+ +E REQ +RE+ ++ +
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393
Query: 884 ALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKE-----KLFNEHIEALTKKKRE 938
L + + + LR++ + L RE++E K E E K+++E
Sbjct: 394 QLRREQQLRREQQLR-REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
Query: 939 HFRQLL---DETSAITLTSTWKEVKKIIKED--PRCIKFSSSDRKKQRE--------FEE 985
R L +ET +++K+ +E+ R +K +R++Q+E +E
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512
Query: 986 YIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLK-DVEKILQNDKRYLVLDCVPE 1044
R++ + + + L + + ++ + +Q LK + EK L+ ++R L E
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE 572
Query: 1045 ERR 1047
ERR
Sbjct: 573 ERR 575
Score = 59.3 bits (142), Expect = 2e-08
Identities = 101/581 (17%), Positives = 243/581 (41%), Gaps = 93/581 (16%)
Query: 441 ELKEKEKLEEKIKEPIKE---PSEEPLPMETEEE----DPKEEPIKEIKEEPKEEEMTEE 493
E +E+++ +E+ + ++ P EE L E ++E D K + K++ E +EE+ +
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 494 EKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQE 553
E + + +E++ + +R + + R + D+ +E
Sbjct: 1333 ETDRK------------------FREEEQL----------LQEREEQPLRRQERDRKFRE 1364
Query: 554 PP------HKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELM-----EEINEDEPV 602
+K +EE ++LR + + +KEEQ+L +++ +D
Sbjct: 1365 EELRHQEQGRKFLEEEQRLR----------RQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 603 KAKKRKRDDNKDIDSEKEAAMEAEIKAA-RERAIVPLEARMKQFKDMLLERGVSAFSTWE 661
K ++ ++ ++ K E +++ RER + E +++Q + E
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Query: 662 KE-LHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEER-REKKNKIMQAKEDFKKMMEEAK 719
++ LH+ D ++L + R+Q D+ K R +E R +E + K ++ ++ + + K
Sbjct: 1475 EQQLHRQERDRKFLEEEQQLRRQERDR--KFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532
Query: 720 F-----NPRATFSEFAAKHAKDSRFKAIEKMK-DREALFNEFVAAARKKEKEDSKTRGEK 773
F R + +D +F+ E+++ +RE RK E+ K R ++
Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592
Query: 774 IKSDFFE---LLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSM-REDLFKQYIEKIAKN 829
+ F E L Q R + + E + + + + R++ ++++E+ +
Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652
Query: 830 LDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDM 889
E+E++L + RE E+ +Q+ +Q + +R+R+ + E+ ++ +
Sbjct: 1653 RRQEREQQLRHDR--DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER----- 1705
Query: 890 VRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSA 949
R+ L+++ + L + +E+ + E +++E +R++L+E
Sbjct: 1706 ----------ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQL 1755
Query: 950 ITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDK 990
+ ++ ++ R KF ++ +Q E+ +R +
Sbjct: 1756 RP-----EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Score = 33.9 bits (76), Expect = 0.85
Identities = 40/236 (16%), Positives = 105/236 (44%), Gaps = 24/236 (10%)
Query: 800 VESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKAR 859
++ + R + S+ +D ++ ++ + D + E+E ++ R + +ERE + +
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 860 SEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLERE 919
SE+ + ++ +R++ +R+E + + W + ++ + +S E E
Sbjct: 155 SEKQERLE-QRDRQRRDEELWRQRQ-----------EWQEREERRAEEEQLQSCKGHETE 202
Query: 920 E---KEKLFNEHIEALTKK----KREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKF 972
E +E+L + L +K K++ R+ D W++ + +++++ K
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE--KL 260
Query: 973 SSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEK 1028
+ ++QRE +E ++ K + + L +E + + ++L +E K E+
Sbjct: 261 QEEEPQRQRELQE---EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 92.4 bits (228), Expect = 2e-18
Identities = 132/653 (20%), Positives = 278/653 (42%), Gaps = 88/653 (13%)
Query: 411 VSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIK-EPSEEPLPMETE 469
+ E T+ + A Y N T E +K EL+EK L E K I+ E +E
Sbjct: 199 IEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERA 258
Query: 470 EEDPKEEPIKEIKEE--PKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYN 527
+ + ++EE +EEE+ E+EK +K + +W +ER+
Sbjct: 259 KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEE------------KMWRQEERL---- 302
Query: 528 PTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIK 587
R + R +K+ ++ K+ E+ K+LR + ++ + ++
Sbjct: 303 ---------REQEGKMREQEEKMWRQ--EKRLREQEKELREQEKELREQKELREQEEQMQ 351
Query: 588 EEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKD 647
E++E M E E + +K R + + + EK+ + + +E + + R+++ ++
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411
Query: 648 MLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQA 707
+ E+ WE ++ K+ +E K++ +Q KTR +EE+ +++ +I
Sbjct: 412 RMREQE----KMWE-QVEKM-----------REEKKMQEQEKKTRDQEEKMQEEERI--- 452
Query: 708 KEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEK--- 764
+E KKM EE E + ++ K E M ++E + +KEK
Sbjct: 453 REREKKMREE----------EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 765 -EDSKTRGEKIKSDFFELLSNHHLDSQSR--WSKVKDKVESDPRYKAVDSSSMREDLFKQ 821
E + + EKI ++ + Q + W + K + + D ++ + +E
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 562
Query: 822 YIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQN 881
E++ K +++K +++ ++ R RERE +K R E+ ++E + ++EE +Q
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMREEERMRERE-KKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 882 FKALL----SDMVRSSDVSWSDTRRTLRKDHR-WESGSLLEREEKEKLFNEHIEALTKKK 936
+ + M + W + ++ + WE L E+KEKL+ EH + ++K
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL--PEQKEKLW-EHEKMQEQEK 678
Query: 937 REHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKA 996
+ + + E + + +E K +E R + KK RE EE +R+
Sbjct: 679 MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMRE------- 731
Query: 997 DFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKL 1049
+ + + + +K+ ++ ++ + EK+ + +++ +PE++ KL
Sbjct: 732 -------QEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL 777
Score = 90.5 bits (223), Expect = 8e-18
Identities = 126/591 (21%), Positives = 247/591 (41%), Gaps = 68/591 (11%)
Query: 433 ESTWEKPQELKEKEK-LEEKIKE--PIKEPSEEPLPMETEEEDPKEEPIKEIKEEPK--- 486
E W + + L+E+EK L E+ KE KE E+ M+ +EE E+ K ++E K
Sbjct: 314 EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR 373
Query: 487 -EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLS--MWDRPDDLIG 543
EE + E+EK ++ + +W DER+ R MW++
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEER-----MWEQDERLREKEERMREQEKMWEQ------ 422
Query: 544 RADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINE----- 598
V+K+ +E KK E+ KK R M ++ + ++EE+E M E E
Sbjct: 423 ---VEKMREE---KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 476
Query: 599 DEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFS 658
+E + ++ K + + +KE E E +E I E +++ ++M +
Sbjct: 477 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK----K 532
Query: 659 TWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAK--EDFKKMME 716
W +E + D + ++ +++ DQ K +EER EKK + + K + +KM E
Sbjct: 533 MWRQEKMREQEDQMW-----EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE 587
Query: 717 EAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKS 776
E + R E + ++ + EKM+++E E ++E++ + + +
Sbjct: 588 EERMRER----EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 777 DFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEK 836
+ + Q R + K+K+ + + + +E+ + + K + EK+
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703
Query: 837 ELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSD----MVRS 892
+ + R E S+RERE+ K R E+ ++E + ++EE +Q + + + M
Sbjct: 704 WDQEKMREEESMREREK---KMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQ 760
Query: 893 SDVSWSDTRRTLRKDHRWESGSL------LEREEKEKLFNEHIEALTKKKREHFRQLLDE 946
+ W R +K+ WE + E+EEK + E + +K R ++ +
Sbjct: 761 EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQ 820
Query: 947 TSAI---------TLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIR 988
+ W + +K+ ++ + + +K RE EE +R
Sbjct: 821 EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMR 871
Score = 81.6 bits (200), Expect = 4e-15
Identities = 102/576 (17%), Positives = 257/576 (44%), Gaps = 84/576 (14%)
Query: 429 NRTLESTWEKPQELKEKEKL-----------EEKIKEPIKEPSEEPLPMETEEEDPKEEP 477
N E W + +EL+E+EK EE+++E + E+ M +E+ +E+
Sbjct: 268 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQE 327
Query: 478 IKEIKEEPKE----EEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLS 533
KE++E+ KE +E+ E+E+ Q+ + +W +E++
Sbjct: 328 -KELREQEKELREQKELREQEEQMQEQEEK------------MWEQEEKM----REQEEK 370
Query: 534 MWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSI-QKWQFSMSAIKEEQEL 592
MW + + L + K+ E+ +K+R M ++ + ++E++++
Sbjct: 371 MWRQEERLWEQ-----------EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 419
Query: 593 MEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLER 652
E++ E ++ +K+ ++ K ++E E E RE+ + E M++ ++ + ++
Sbjct: 420 WEQV---EKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 476
Query: 653 GVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDF- 711
+ + EKE + P++++++++Q EE+ E++ KI +E +
Sbjct: 477 EENMWEQEEKEWQQQRL--------PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG 528
Query: 712 --KKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREA-LFNEFVAAARKKEKEDSK 768
KKM + K + +D ++ EKM+D+E ++++ +K ++++ K
Sbjct: 529 QEKKMWRQEKM-----------REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577
Query: 769 TRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAK 828
T ++ K + + R + K + E + + + +E+ ++ EK+ +
Sbjct: 578 TWDQEEKM---------REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWE 628
Query: 829 NLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSD 888
+ +E+E + + E + E+ ++ R + KE E E+ + +E +Q + + +
Sbjct: 629 QEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWE 688
Query: 889 MVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETS 948
+ + ++T ++ E S+ ERE+K + E + +K +E ++ ++
Sbjct: 689 QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
Query: 949 AITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFE 984
+ W++ +K+ +++ + + +K++ +E
Sbjct: 749 EM-----WEQEEKMWEQEEKMWEQQRLPEQKEKLWE 779
Score = 63.5 bits (153), Expect = 1e-09
Identities = 98/472 (20%), Positives = 204/472 (43%), Gaps = 42/472 (8%)
Query: 430 RTLESTWEKPQELKEKEKLEEKIKEPIKEPSE-----EPLPMETEEEDPKEEPIKEIKEE 484
R E ++ + ++E+EK + +E ++E E E E EE++ +++ + E KE+
Sbjct: 440 RDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499
Query: 485 PKEEE--MTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRL---SMWDRPD 539
E+E +EEK ++ + + +W G E+ + R MW++ +
Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQE-------EMW-GQEKKMWRQEKMREQEDQMWEQEE 551
Query: 540 DLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINED 599
+ + +E KK E+ KK M ++ + ++EE+E+M E E
Sbjct: 552 KMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 611
Query: 600 EPVKAKKRKRDDNK------DIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLE-R 652
+ +K + + K + ++E E E K + + + R+ + K+ L E
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 671
Query: 653 GVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFK 712
+ +++ KI + ++ K+ +DQ K R EE RE++ K M+ +E+
Sbjct: 672 KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ-EKMREEESMREREKK-MREEEEMM 729
Query: 713 KMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEK--EDSKTR 770
+ EE + E + ++ ++ EKM ++E E +KEK E K +
Sbjct: 730 REQEE-----KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 784
Query: 771 GEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKI---A 827
++ + E + + + + K++ + E R + E ++ Q EK+
Sbjct: 785 EQEKIWEQEEKMRDQEEKMRGQEEKMRGQ-EEKMRGQEEKMWGQEEKMWGQE-EKMWGQE 842
Query: 828 KNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI 879
+ + ++EK E+ E +RE+E +K R ++ K ++E + +EE I
Sbjct: 843 EKMWGQEEKMEEKMQGQEEKMREQE---EKMRGQEEKMREQEEKMRGQEEKI 891
Score = 48.1 bits (113), Expect = 4e-05
Identities = 66/370 (17%), Positives = 160/370 (43%), Gaps = 62/370 (16%)
Query: 414 WTEYKTADGKTYYYNNRTLESTW-----EKPQELKEKEKLEEKIKEPIKEPSEEPLPMET 468
W + + + KT +T + E+ +E ++K + EE++ +E +E
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 469 EEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYN- 527
E+E+ E +E K + +EE+M E+E+ +W +E+++
Sbjct: 621 EQEEKMWE--QEEKMQEQEEKMWEQEEK-------------------MWEQEEKMWEQQR 659
Query: 528 -PTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAI 586
P + +W+ H+K M+E +K++ + +K +
Sbjct: 660 LPEQKEKLWE-------------------HEK-MQEQEKMQEQEEKIWEQEKMEKKTQEQ 699
Query: 587 KEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFK 646
+++ E++ E+E ++ +++K + +++ E+E M+ + + +E+ E M + +
Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ-----EEEMWEQE 754
Query: 647 DMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQ 706
+ + E+ WE++ + + +E++++++Q K R +EE+ + + M+
Sbjct: 755 EKMWEQ---EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811
Query: 707 AKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKE- 765
+E+ + EE + E ++ + EKM +E E + +K +E
Sbjct: 812 GQEEKMRGQEEKMWG-----QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ 866
Query: 766 DSKTRGEKIK 775
+ K RG++ K
Sbjct: 867 EEKMRGQEEK 876
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 84.7 bits (208), Expect = 4e-16
Identities = 91/402 (22%), Positives = 130/402 (32%), Gaps = 43/402 (10%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGP 91
P PPP+ P + P PP P P PP P P++ +P P PP P
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLAT----PLPLAPP--SPSAPPSLQTLPSPPATPPSQAP 369
Query: 92 PHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTP----ALPPTEEIWVENKTPDGKV 147
P + PP PP PP + P + AP +P +L T +
Sbjct: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429
Query: 148 YYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQA 207
+ R +++ T P + +P L A + A Q +
Sbjct: 430 LTMSPRQTQASLTSPS--RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487
Query: 208 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPA 267
QA + A QA + + ++ Q TP S
Sbjct: 488 PLQA---------------LSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532
Query: 268 PAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQD-QTPSSAVSVATPTV--SVSTPAP 324
P + S + P T++ T +T P Q P S ++ P S++TP P
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP 592
Query: 325 TATPVQTVPQ----PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGV 380
A P P P P P A P P A+P PP PL + P P
Sbjct: 593 QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA 652
Query: 381 LPGMA---------PPIVPMIHPQVAIAASPATLAGATAVSE 413
+A PP P + + ASP AT S+
Sbjct: 653 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694
Score = 80.5 bits (197), Expect = 8e-15
Identities = 97/382 (25%), Positives = 132/382 (34%), Gaps = 41/382 (10%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGP-PPPPRPPFGRPPFDPNMPPMPPPGGIPPPMG 90
PA PP + + P P +++ P PPP PP + PF P P P PP
Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPVSPSATPPSQA 695
Query: 91 PPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150
PP L PP PP PP M P PP AP A PP + V P
Sbjct: 696 PPSLAAPPLQVPPSPPASPP---MSPSATPPPQAPPPLAAPPLQ---VPPSPPA------ 743
Query: 151 NARTRESAWTKPDGVKVIQQSELTPMLAA-QAQVQAQAQAQAQAQAQAQAQAQAQAQAQA 209
+ P + P+LAA QV A A+ QA A
Sbjct: 744 ---------SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA---PPA 791
Query: 210 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPA 269
A QA A QA A QA A P + +P
Sbjct: 792 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851
Query: 270 VSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPV 329
+ TP TS + ++A P ++PSS +S P ++ + + T+TP
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS--GPDLAGHSSSATSTPE 909
Query: 330 QTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVM-----VPP--FRVPLPGMPIPLPGVL- 381
+ + P + P P + A P PP FR PG P+P P
Sbjct: 910 ELRGY---DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR-GAPGAPLPWPPATG 965
Query: 382 PGMAPPIVPMIHPQVAIAASPA 403
PG A + + + +A+PA
Sbjct: 966 PGSADGLCTIYETEGPESATPA 987
Score = 77.8 bits (190), Expect = 5e-14
Identities = 100/391 (25%), Positives = 126/391 (32%), Gaps = 67/391 (17%)
Query: 34 PPPNAVMRGPPPLMRPPPPFGM--MRGPPPPPRPPFGRPPFDPNMPPMPPPGGI--PPPM 89
P N PPPL P + PP P P PP PP P I PPP
Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 90 GPPHLQRPPFM----PP--PMSSMPP--PPGMMFPPGMPPVTAPGTPALPPTEEIWVENK 141
PP L PP PP P+++ PP PP + PP P + P +P L P
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA------- 646
Query: 142 TPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQA 201
TP S P A +QA QA
Sbjct: 647 TP---------------------------SPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 679
Query: 202 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTP 261
A A +QA A Q A + QA A+ P
Sbjct: 680 PASPPVSPSATPPSQAPPSLAAPP-----LQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734
Query: 262 TTSSPAPAVSTSTS-SSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVS 320
P+P S S S+TP A + S P + +P + P
Sbjct: 735 LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP----- 789
Query: 321 TPAPTATPVQTVPQPHPQTLPPAVPHS----VPQPTTAIPAFPPVMVPPFRVPLPGMPIP 376
PA P+Q +P P P + P P S +P A P PP P PL +P P
Sbjct: 790 -PALATPPLQALPSP-PASFPGQAPFSPSASLPMSPLATP--PPQAPPVLAAPLLQVP-P 844
Query: 377 LPGVLPGM-APPIVPMIHPQVAIAASPATLA 406
P P + AP P P +++ TLA
Sbjct: 845 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 875
Score = 70.9 bits (172), Expect = 6e-12
Identities = 93/372 (25%), Positives = 118/372 (31%), Gaps = 53/372 (14%)
Query: 46 LMRPPPPFGMMRGPPPPPRPPFG--RPPFDPNMPPMPPPG--GIPPPMGPPHLQRPPFMP 101
L+ PP PP PP PP + N+P + PP P+ PHL+ PP
Sbjct: 507 LIMPPLETQSSLAPPSLQTPPASLTTPPLE-NLPSLAPPPLQTASAPLTTPHLETPPCPA 565
Query: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTK 161
P PP P PP P A P PP A
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPP-------------------------ALAS 600
Query: 162 PDGVKVIQQSELTPMLAAQAQVQ---AQAQAQAQAQAQAQAQAQAQAQAQAQA-QAQAQA 217
P ++ + L+P+ Q A QA A A QA A A
Sbjct: 601 PP-LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
Query: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTS-S 276
QA QA A V QA A+ P P+P S S S
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719
Query: 277 STPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPH 336
+TP A + S P + +PS+ TP P P+ P
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA------------TPPPRVPPLLAAP--- 764
Query: 337 PQTLPPAVPHSVPQPTTAIPA--FPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHP 394
P +PP+ P S+P A P PP + P LP P PG P +PM
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
Query: 395 QVAIAASPATLA 406
+P LA
Sbjct: 825 ATPPPQAPPVLA 836
Score = 63.9 bits (154), Expect = 8e-10
Identities = 97/408 (23%), Positives = 142/408 (34%), Gaps = 52/408 (12%)
Query: 33 APPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPF--------DPNMPPMPPPGG 84
A P + PP RPPPP GR P +P P G
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 85 IPPPMGPPHLQRPPFMPPPMSS----MPP----PPGMMFPPGMPPVTAPGTPALPPTEEI 136
P R P PP S PP PG + PG T P I
Sbjct: 79 --PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 137 WVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQ 196
E GK R+ SA + D S TP + A + A +
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRD------TSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 197 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV 256
A + A+ + + ++ + A + + A+ + A +Q + + A
Sbjct: 191 RPAPS---ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 257 GASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPT 316
S+P S P+ A T + + PS A Q TP +D P+ ++P
Sbjct: 248 PLSSPARSGPS-ARGTPRAPAHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSSP- 303
Query: 317 VSVSTPAPTATPVQTVPQPH------PQTLPPAVPHSVPQP-TTAIPAFPPVM------- 362
++TP+P+ T + VP P P TLPP+ P + P P P+ PP +
Sbjct: 304 --LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP 361
Query: 363 -VPPFRVPLPGM---PIPLPGVLPGMAPPIVPMIHPQVAIAASPATLA 406
PP + P P M P+ P L + P VP ++ A P+ LA
Sbjct: 362 ATPPSQAP-PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA 408
Score = 63.2 bits (152), Expect = 1e-09
Identities = 91/365 (24%), Positives = 111/365 (30%), Gaps = 51/365 (13%)
Query: 29 FRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
F PA PP + PP P ++ PP PP P P P PP PPP
Sbjct: 677 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-------PMSPSATPPPQAPPP 729
Query: 89 MGPPHLQRPPFMP--PPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGK 146
+ P LQ PP P PPMS P PP +PP+ A +PP+
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATP-----PPRVPPLLAAPPLQVPPSPP----------- 773
Query: 147 VYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQ 206
A S KP P A A QA A QA
Sbjct: 774 -----ASLPMSPLAKP------------PPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
Query: 207 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSP 266
A A QA A Q A +QA + S P +
Sbjct: 817 ASLPMSPLATPPPQA-PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 875
Query: 267 APAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTT---QDQTP-SSAVSVATPTVSVSTP 322
S +PSST S A + STP D P A + P ++
Sbjct: 876 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 935
Query: 323 APTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVL- 381
P A P P A +P P P + + P P PG L
Sbjct: 936 HPAAWSRGPAP---PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALD 992
Query: 382 PGMAP 386
PG +P
Sbjct: 993 PGPSP 997
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 84.3 bits (207), Expect = 5e-16
Identities = 95/396 (23%), Positives = 140/396 (35%), Gaps = 31/396 (7%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPP-PPRPPFGRPPFDPNMPPMPPPGGIPPP- 88
G A PP+ P + P P G PP P PP PP P PPP G P P
Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336
Query: 89 -MGPPHLQRPPFMP---PPMSSMPPPPGMMFPPGMPPVTAP---GTPAL-PPTEEIWVEN 140
+ PP + P +P P P P P PP P G PA+ PP+ +
Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP-TPPAATPSHKGGPAMTPPSPKRGPAI 1395
Query: 141 KTPDGK-----VYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQA 195
+P G V + + + +G + +LTP ++ A
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455
Query: 196 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQA 255
A ++ A + + A + + +A A +
Sbjct: 1456 PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE 1515
Query: 256 VGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATP 315
V A+ + P +T S TP+ T + A TV +P P+ + ATP
Sbjct: 1516 VPATPSSRRDPIAPTATLLSKKTPA-TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP 1574
Query: 316 TVSVSTPAPTATP--VQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGM 373
+ ++ P TP + P P +PPAV + P P A PP + PP P G
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAV--TSPSPKEA--PTPPAVTPP--SPEKGP 1628
Query: 374 PIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGAT 409
P P P +PP+ P ++ SP + A T
Sbjct: 1629 ATPAPKGTP-TSPPVTPS-----SLKDSPTSPASVT 1658
Score = 74.3 bits (181), Expect = 6e-13
Identities = 91/391 (23%), Positives = 125/391 (31%), Gaps = 40/391 (10%)
Query: 34 PPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPH 93
P P + P P P PP PP P G P P PP P P G P
Sbjct: 925 PAPKGIPASPSPKGAPTPPAAT------PPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978
Query: 94 LQRPPFMPPPMSSMPP----------PPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTP 143
P P P ++ PP P G PP + P + G+PA P + TP
Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK---GASTP 1035
Query: 144 DGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQA 203
A T S P + + + TP + A + A
Sbjct: 1036 P-------AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088
Query: 204 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQ---AQAVGAST 260
+ + A A + A + A + A
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 261 PTTSSPAPAVSTSTSSSTPSSTTSTTTTAT--SVAQTVSTPTTQDQTPSSAVSVATPTVS 318
PTT + P ++ P TT AT S ++TP+ + + A + +P
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 319 VSTPAP---TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFP---PVMVPPFRVPLPG 372
++TP+P TP T P P P+ P P A P P P PP P P
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPS-PKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 373 MPIPLPGVLPGMA-PPIVPMIHPQVAIAASP 402
P P + G+A PP +P V SP
Sbjct: 1268 AATP-PSLKGGLATPPHKGAPNPAVVTPPSP 1297
Score = 72.8 bits (177), Expect = 2e-12
Identities = 95/399 (23%), Positives = 131/399 (32%), Gaps = 46/399 (11%)
Query: 30 RGPAPPPNAVMRGPPPLMRPPPPFGMMRGP---PPPPR-----PPFGRPPFDPNMPPMPP 81
+G PP A P P P G P PP P+ PP P P P P
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
Query: 82 PGGI--PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTP-ALPPTEEIWV 138
GG+ PPP G P P ++ P P G + P PP AP TP A PP+ + +
Sbjct: 1137 KGGLATPPPKGAP--------TTPAATPPSPKGGLATP--PPKGAPTTPAATPPSPKGGL 1186
Query: 139 ENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQ 198
+P G T + P G + P A + + A
Sbjct: 1187 ATPSPKGA-----PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241
Query: 199 AQAQAQAQAQAQAQAQAQAQ-AQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVG 257
A + A + A A + A + V +
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301
Query: 258 ASTPTTSSPAPAVST----STSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVA 313
A++P +P P +T S TP + T A + TPT TPSS
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 314 T------PTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFR 367
T PT +TP+ P T P P PA+P PT+ P ++P
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSP---KRGPAIPSPKGDPTS------PAVIPLSP 1412
Query: 368 VPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLA 406
P P+ G + P V++ +PAT A
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA 1451
Score = 71.2 bits (173), Expect = 5e-12
Identities = 104/422 (24%), Positives = 139/422 (32%), Gaps = 54/422 (12%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFG------MMRGPPPPPRPPFGRPPFDPNMP-----PMP 80
PA P PP PP P G + +G P P P P P P P
Sbjct: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082
Query: 81 PPGGIPPPMGPPHLQRPPFMPPPMSSMPPPP--GMMFPPGM------------------- 119
P P P G P P P P ++ PP P G+ PP
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT 1142
Query: 120 -PPVTAPGTP-ALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPML 177
PP AP TP A PP+ + + P G T + P G + P
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGA-----PTTPAATPPSPKGGLATPSPKGAPTT 1197
Query: 178 AAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 237
A + + A A + A + A +
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257
Query: 238 QAQAQVQAQVQAQVQAQAVGASTPT-TSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTV 296
A + G +TP +P PAV T S +T+ T A T
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317
Query: 297 STPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTL-PPAVPHSV--PQPTT 353
+P TP + P +V+ P+P TP T+P P + P P S P P
Sbjct: 1318 PSPKGSPGTPPPKGAPTPP--AVTPPSPKGTP--TLPATTPSSKGGPTTPSSKEGPTPPA 1373
Query: 354 AIPAFP--PVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAV 411
A P+ P M PP P G IP P P +P ++P + P+ A A+P T GA
Sbjct: 1374 ATPSHKGGPAMTPP--SPKRGPAIPSPKGDP-TSPAVIP-LSPKKA-PATPVTREGAATP 1428
Query: 412 SE 413
S+
Sbjct: 1429 SK 1430
Score = 63.9 bits (154), Expect = 8e-10
Identities = 98/421 (23%), Positives = 124/421 (29%), Gaps = 62/421 (14%)
Query: 32 PAPPPNAVMRGP----------PPLMRPPPPFGMMRGPPP--PPRPPFGRPPFDPNMP-- 77
PA P + GP PP PP P G P P P PP PP P
Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025
Query: 78 -PMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEI 136
P P PP PP + P P P P P P P TP+L
Sbjct: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP---SPKGGPATPSLKGA--- 1079
Query: 137 WVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQ 196
TP A T S P G + PM A +
Sbjct: 1080 ----PTPP-------AATPPS----PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124
Query: 197 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV 256
A A + A + A + A +
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184
Query: 257 GASTPT-TSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATP 315
G +TP+ +P +T S +T S T+ A T +P TPS + TP
Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244
Query: 316 TVSVSTP--APTATPVQTVPQPHPQTLPPAV-------PH-SVPQPTTAIPAFP---PVM 362
+ +P P P + P P P PP++ PH P P P P P
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTP-PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303
Query: 363 VPPFRVPLPGMPIP-----LPGVLPGMAPPIVPMIHP------QVAIAASPATLAGATAV 411
PP P P P PG P P P + P A +P++ G T
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363
Query: 412 S 412
S
Sbjct: 1364 S 1364
Score = 57.4 bits (137), Expect = 7e-08
Identities = 106/526 (20%), Positives = 170/526 (32%), Gaps = 64/526 (12%)
Query: 16 PGELRMAQQQALRFRGPAPP-----PNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRP 70
P L+ A + GPA P P PP PP P + P P P
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
Query: 71 PFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPP--MSSMPP----PPGMMFPPGMPPVTA 124
P +P + P P P +R P P +S P P + PP M +
Sbjct: 1500 MGAPTLPAVIPSSPKEVP-ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP 1558
Query: 125 PGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWT-KPDGVKVIQQSELTPMLAAQAQV 183
TPA+P +E TP K S + P +++ +T +A
Sbjct: 1559 KKTPAIPTPKEA---PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615
Query: 184 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQ 242
+ + A + + + + + A + A QA A+
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675
Query: 243 VQAQVQAQVQAQAVGASTPTTSSPA-----------------PAVSTSTSSSTPSSTTST 285
+V STP ++P P S S P ST +
Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAP 1735
Query: 286 TTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTL--PPA 343
+ T +D + S +A P STP A + +P+P ++ P+
Sbjct: 1736 APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPS 1795
Query: 344 VPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPA 403
P S+P + +P PP F PG+ VL + P+ P ++ P
Sbjct: 1796 PPVSLPLAPSPVPTLPPKQ--QFLPSSPGL------VLESPSKPLAPADEDELLPLIPPE 1847
Query: 404 TLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEP 463
++G ++ N T +S K+ + + K E +
Sbjct: 1848 PISGGVPF-----------QSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDE 1896
Query: 464 LPMETEEEDPKEEPIK--------EIKEEP-KEEEMTEEEKAAQKA 500
E EE+D + + EI EEP + + + EK A+KA
Sbjct: 1897 SVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKA 1942
Score = 53.5 bits (127), Expect = 1e-06
Identities = 70/324 (21%), Positives = 116/324 (35%), Gaps = 47/324 (14%)
Query: 88 PMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKV 147
P+ P + P P P ++ P ++ P +P +P+LPP TP G
Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVP--SPSLPPAG-------TPPGT- 748
Query: 148 YYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQ-AQAQAQAQAQAQAQAQAQAQ 206
K DG+ S L P+ ++ + + + A A A ++ A +
Sbjct: 749 ------------KKVDGIS--HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794
Query: 207 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVG-----ASTP 261
+ Q + + A + + V+A + G A+T
Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854
Query: 262 TTSSPAPAVSTSTSSSTPSSTTSTTTTA--TSVAQTVSTPTTQD--------QTPSSAVS 311
+ + P+P + + S+ TP S T T V+ P ++ Q P+ +++
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914
Query: 312 VATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQ--PTTAIPAF---PPVMVPPF 366
++P + +TPAP P P P PPA P+ P T P + PP PP
Sbjct: 915 SSSPKKARATPAPKGIPAS--PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972
Query: 367 RVPLPGMPIPLPGVLPGMAPPIVP 390
P P P P A P P
Sbjct: 973 PKGGPATPSPKGAPTPPAATPPSP 996
Score = 52.4 bits (124), Expect = 2e-06
Identities = 91/418 (21%), Positives = 122/418 (29%), Gaps = 39/418 (9%)
Query: 8 GGESERFNPGELRMAQQQALRFRG----PAP-----PPNAVMRGPPPLMRPPPPFGMMRG 58
G S +P E + +L F+G PA PP+ P + P P G+
Sbjct: 822 GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLP 881
Query: 59 PPPPPRPPFGRPPFDPNMPPMPPPGGIPP---PMGPPHLQRPPFMPPPMSSMPPPPGMMF 115
P P P PF P P P P P R P + + P P G
Sbjct: 882 PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT 941
Query: 116 PPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTP 175
PP P + G PA P + W P + A P G TP
Sbjct: 942 PPAATPPSPKGGPATPSPK--W----APTPPAATPPSPKGGPATPSPKGAP-------TP 988
Query: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 235
A + + A + + A A A + + A
Sbjct: 989 PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 236 QAQAQAQVQAQVQAQVQAQAVGASTPT-TSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQ 294
A + + G +TP+ +P P +T S +T S A
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA 1108
Query: 295 TVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTA 354
T +P TP PT +TP + T P T P A P P P
Sbjct: 1109 TPPSPKGGLATPPHK---GAPTTPAATPPSPKGGLATPPPKGAPTTPAATP---PSPKGG 1162
Query: 355 IPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVS 412
+ PP P P P G+A P P P A P+ G S
Sbjct: 1163 LATPPPKGAPTTPAATP------PSPKGGLATP-SPKGAPTTPAATPPSPKGGLATPS 1213
Score = 35.0 bits (79), Expect = 0.38
Identities = 68/306 (22%), Positives = 99/306 (32%), Gaps = 60/306 (19%)
Query: 251 VQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVS--TPTTQDQTPSS 308
V A + ++ P +P A TST ++T S T + V T TT P++
Sbjct: 645 VAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTA 704
Query: 309 AVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFR- 367
+ + +T AP AT V L P +P SVP P+ PP PP
Sbjct: 705 SENCPVAPSPQNTCAPLATLV----------LAPEIPKSVPSPS-----LPPAGTPPGTK 749
Query: 368 -----------VPLPGMPIPLP-------------GVLPGMAPPIVPM---IHPQVAI-- 398
P+ P P G L +A P+ + PQ
Sbjct: 750 KVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809
Query: 399 ----AASPATLAG--ATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKI 452
+A P T G ++ VS + + ++ +T P K
Sbjct: 810 TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869
Query: 453 KEPIKE------PSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATA 506
P+ P E P P PKE P ++ MT +A P A
Sbjct: 870 VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP-APK 928
Query: 507 PIPGTP 512
IP +P
Sbjct: 929 GIPASP 934
Score = 34.7 bits (78), Expect = 0.50
Identities = 45/188 (23%), Positives = 68/188 (36%), Gaps = 29/188 (15%)
Query: 222 QAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSP--------------- 266
+A A Q Q QA+ V A A+G PT P
Sbjct: 4 EATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQ 63
Query: 267 -APAVSTSTSSSTPSST---TSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTP 322
+P S ST +STP S++ TA + PT +S A +++++P
Sbjct: 64 ASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPA--ALALASP 121
Query: 323 APTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLP 382
T T P L PHSV + + AFPP ++ P + + G +
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSS----AFPPNLL----TSPPSVAVAESGSVI 173
Query: 383 GMAPPIVP 390
++ PI P
Sbjct: 174 TLSAPIAP 181
Score = 30.8 bits (68), Expect = 7.2
Identities = 87/420 (20%), Positives = 129/420 (30%), Gaps = 60/420 (14%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNM--PPMPPPG------ 83
P P P+ + PL P P P P P F PN+ PP+ P
Sbjct: 66 PFPSPSTI--ASTPLEVPFPQSSSGTALPLGTAPE--APTFLPNLIGPPISPAALALASP 121
Query: 84 -------GIPPPMGP-------PH-LQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTP 128
G P P PH +Q+ PP + + PP + + ++AP P
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181
Query: 129 ALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQ 188
+ P T NK P V + + P V + +TPM + Q+ V + Q
Sbjct: 182 SEPKTN----LNKVPSEVV-----PNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQ 232
Query: 189 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQ 248
A A Q + + Q + A Q+
Sbjct: 233 T-------TPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV 285
Query: 249 AQVQAQAVGASTPTT------SSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVST--PT 300
+ G +TP S AP +S S T + + +T+S +
Sbjct: 286 VTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSS 345
Query: 301 TQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPT------TA 354
T PS SV P S + P V P P + P+ T+
Sbjct: 346 TGASYPSQR-SVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATS 404
Query: 355 IPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMI--HPQVAIAASPATLAGATAVS 412
P + P PL +P + P++ +P AA T AT VS
Sbjct: 405 FSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVS 464
>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
Length = 478
Score = 84.0 bits (206), Expect = 7e-16
Identities = 103/387 (26%), Positives = 145/387 (37%), Gaps = 55/387 (14%)
Query: 7 DGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPP 66
D S F P ++ Q P PP G PP + P +M G PP
Sbjct: 120 DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPP-----LMPGVPPLMP-- 172
Query: 67 FGRPPFDPNMPP-MPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAP 125
G PP P MPP M P GG+ PP GP PP MP MPPP + PG+PP+T
Sbjct: 173 -GMPPVMPGMPPGMMPMGGMMPP-GP---GIPPLMPGMPPGMPPP---VPRPGIPPMTQA 224
Query: 126 GTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQA 185
+ P + N+ P A T +P K P+ + Q+
Sbjct: 225 QAVSAP-----GILNRPP--------APTATVPAPQPPVTK--------PLFPSAGQMGT 263
Query: 186 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQA 245
+ + A + +++ A ++A + AQAQA Q + A +
Sbjct: 264 PVTSSSTASSNSES---LSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKP 320
Query: 246 QVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQT 305
A Q+ A ST +++ PA S TS +TTS T+ + +S + Q
Sbjct: 321 TFPAYTQSTASTTSTTNSTAAKPAASI-TSKPATLTTTSATSKLIHPDEDISLEERRAQL 379
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPP 365
P + P P P+ P + P P +PQ P PP
Sbjct: 380 PK---------YQRNLPRPGQAPIGNPPVGPIGGMMPPQP-GIPQQQGMRPPMPP--HGQ 427
Query: 366 FRVPLPGMPIPLPGVLP--GMAPPIVP 390
+ GMP LPG +P G PP+VP
Sbjct: 428 YGGHHQGMPGYLPGAMPPYGQGPPMVP 454
Score = 79.7 bits (195), Expect = 1e-14
Identities = 95/374 (25%), Positives = 143/374 (38%), Gaps = 69/374 (18%)
Query: 44 PPLMRPP-PPFGMMRGPPP--PPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFM 100
PP+ +P PP G PP PP P G PP P MPP+ P G+PP M P M
Sbjct: 140 PPMAQPGLPPVPGAPGMPPGIPPLMP-GVPPLMPGMPPVMP--GMPPGMMP----MGGMM 192
Query: 101 PPPMSSMPPPPGMMFPPGMPP-VTAPGTPALPPTEEI---WVENKTPDGKVYYYNARTRE 156
PP P PGM PPGMPP V PG P + + + + N+ P A T
Sbjct: 193 PPGPGIPPLMPGM--PPGMPPPVPRPGIPPMTQAQAVSAPGILNRPP--------APTAT 242
Query: 157 SAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 216
+P K P+ + Q+ + + A + +++ + A ++A + AQ
Sbjct: 243 VPAPQPPVTK--------PLFPSAGQMGTPVTSSSTASSNSESLS---ASSKALFPSTAQ 291
Query: 217 AQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSS 276
AQA Q + A + A Q+ A ST +++ PA S ++
Sbjct: 292 AQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKP 351
Query: 277 STPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATP-----------TVSVSTPAPT 325
+T +TTS T+ + +S + Q P ++ P + P
Sbjct: 352 AT-LTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQP 410
Query: 326 ATPVQTVPQP----------HPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPI 375
P Q +P H Q +P +P ++P P PP P R P+
Sbjct: 411 GIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM----- 465
Query: 376 PLPGVLPGMAPPIV 389
GM PP++
Sbjct: 466 -------GMRPPVM 472
Score = 48.5 bits (114), Expect = 3e-05
Identities = 42/122 (34%), Positives = 53/122 (43%), Gaps = 23/122 (18%)
Query: 11 SERFNPGE---LRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPF 67
S+ +P E L + Q +++ P P G PP+ P GMM PP+P
Sbjct: 361 SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPV---GPIGGMM-----PPQP-- 410
Query: 68 GRPPFDPNMPPMPPPG-------GIP---PPMGPPHLQRPPFMPPPMSSMPPPPGMMFPP 117
G P PPMPP G G+P P PP+ Q PP +PP P PP M PP
Sbjct: 411 GIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPP 470
Query: 118 GM 119
M
Sbjct: 471 VM 472
Score = 48.1 bits (113), Expect = 4e-05
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 10/81 (12%)
Query: 333 PQPHPQTLPPAVPHSVPQPTTAIPAFPPVM--VPPFRVPL-------PGMPIPLPGVLPG 383
P P +PP +P +P +P PPVM +PP +P+ PG+P +PG+ PG
Sbjct: 149 PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPG 208
Query: 384 MAPPIV-PMIHPQVAIAASPA 403
M PP+ P I P A A
Sbjct: 209 MPPPVPRPGIPPMTQAQAVSA 229
Score = 39.3 bits (90), Expect = 0.020
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 9/70 (12%)
Query: 326 ATPVQTVP-QPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPG---VL 381
+T Q P QP +PP +P P P PP +PP +PG+P +PG V+
Sbjct: 124 STSFQPQPVQPQQGYIPPMAQPGLP-PVPGAPGMPPG-IPPL---MPGVPPLMPGMPPVM 178
Query: 382 PGMAPPIVPM 391
PGM P ++PM
Sbjct: 179 PGMPPGMMPM 188
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 84.0 bits (206), Expect = 7e-16
Identities = 58/125 (46%), Positives = 66/125 (52%), Gaps = 16/125 (12%)
Query: 16 PGELRMAQQQALRFRGPAPP---PNAVMRGPPPLMRPPPPFGMMRGPPP---PPRPPFGR 69
PG + A R P PP P G PP +RPP G+ RGP P PP PP GR
Sbjct: 408 PGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGL-RGPLPRLLPPGPPPGR 466
Query: 70 PPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPM-SSMPPP-PGMMFPPGMPPVTAPGT 127
PP PP PPP G+PP GPP PP +PPP +PPP PGMM PP +PP+ P
Sbjct: 467 PP---GPPPGPPP-GLPP--GPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPL-GPAP 519
Query: 128 PALPP 132
P L P
Sbjct: 520 PGLFP 524
Score = 68.6 bits (166), Expect = 3e-11
Identities = 39/90 (43%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
Query: 44 PPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIP-PPMGPPHLQRPPFMPP 102
PP PP ++ PP P PP G PP P PP PP G P PP G P RPP MP
Sbjct: 393 PPQSVPP---SQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPG 449
Query: 103 PMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
+P + PPG PP PG P PP
Sbjct: 450 LRGPLP----RLLPPGPPPGRPPGPPPGPP 475
Score = 67.8 bits (164), Expect = 5e-11
Identities = 45/105 (42%), Positives = 52/105 (49%), Gaps = 22/105 (20%)
Query: 28 RFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPP 87
R P PPP G PP P PP G+ GPPP P P +PP P P GIPP
Sbjct: 456 RLLPPGPPP-----GRPPGPPPGPPPGLPPGPPPRGPP--------PRLPP-PAPPGIPP 501
Query: 88 PMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
P P + RPP +PP P PPG +FPP P+ PG + PP
Sbjct: 502 PR--PGMMRPPLVPP---LGPAPPG-LFPPA--PLPNPGVLSAPP 538
Score = 57.4 bits (137), Expect = 7e-08
Identities = 60/255 (23%), Positives = 93/255 (36%), Gaps = 59/255 (23%)
Query: 172 ELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 231
ELTP+ A ++ Q + + + ++ + + ++A+ Q+Q Q + ++ +
Sbjct: 326 ELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSD---DSEAEKQSQKQHKEESHSDG 382
Query: 232 QAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATS 291
+ A +Q QA Q+ +Q+QA + P PAP +
Sbjct: 383 TSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP------------------ 424
Query: 292 VAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVP------QPHPQTLPPAVP 345
PT P P A P P P P+ LPP P
Sbjct: 425 ---------------------GPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPP 463
Query: 346 HS-----VPQPTTAIPAFPPVMVPPFRVP---LPGMPIPLPGVLPGMAPPIVPMIHPQVA 397
P P +P PP PP R+P PG+P P PG+ M PP+VP + P
Sbjct: 464 PGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGM---MRPPLVPPLGPAPP 520
Query: 398 IAASPATLAGATAVS 412
PA L +S
Sbjct: 521 GLFPPAPLPNPGVLS 535
Score = 51.2 bits (121), Expect = 5e-06
Identities = 36/94 (38%), Positives = 38/94 (40%), Gaps = 24/94 (25%)
Query: 60 PPPPRPP--FGRPPFDPNMPPMPPPGGIP-------------PPMGPPHLQRPPFMPPPM 104
PP PP PP P PP+ PP P PP G P RPP MP
Sbjct: 393 PPQSVPPSQIQAPPM-PGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLR 451
Query: 105 SSMP------PPPGMMFPPGMPPVTAPGTPALPP 132
+P PPPG PPG PP PG P PP
Sbjct: 452 GPLPRLLPPGPPPGR--PPGPPPGPPPGLPPGPP 483
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 83.6 bits (205), Expect = 9e-16
Identities = 53/115 (46%), Positives = 61/115 (53%), Gaps = 14/115 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP + PPPPP P G PP P +PP PP P
Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1180
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPG-MPPVTAPGTPALPP 132
G GIPPP P + PP P P + +PPP PGM PP PP+ PGT PP
Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP 1235
Score = 79.7 bits (195), Expect = 1e-14
Identities = 52/125 (41%), Positives = 62/125 (49%), Gaps = 14/125 (11%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP + PPPPP P G PP P +PP PP P
Sbjct: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1136
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPPP---GMMFPPGMPPVTAPGTPALPPTEEIWV 138
G GIPPP P + PP P P + +PPPP G PP PP+ G P PP + +
Sbjct: 1137 GAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGVGIPPPPPLPGVGI 1195
Query: 139 ENKTP 143
P
Sbjct: 1196 PPPPP 1200
Score = 79.3 bits (194), Expect = 2e-14
Identities = 52/125 (41%), Positives = 61/125 (48%), Gaps = 14/125 (11%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 1033 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1092
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPPTEEIWV 138
G GIPPP P + PP P P + +PPP PG PP PP+ G P PP + +
Sbjct: 1093 GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPRVGI 1151
Query: 139 ENKTP 143
P
Sbjct: 1152 PPPPP 1156
Score = 77.8 bits (190), Expect = 5e-14
Identities = 52/125 (41%), Positives = 60/125 (48%), Gaps = 14/125 (11%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 989 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1048
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPPTEEIWV 138
G GIPPP P PP P P + +PPP PG PP PP+ G P PP + +
Sbjct: 1049 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGVGI 1107
Query: 139 ENKTP 143
P
Sbjct: 1108 PPPPP 1112
Score = 77.8 bits (190), Expect = 5e-14
Identities = 51/114 (44%), Positives = 58/114 (50%), Gaps = 14/114 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 1011 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1070
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
G GIPPP P PP P P + +PPP PG+ PP PP+ G P PP
Sbjct: 1071 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP-PPPLPGAGIPPPPP 1123
Score = 77.8 bits (190), Expect = 5e-14
Identities = 52/125 (41%), Positives = 59/125 (47%), Gaps = 14/125 (11%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 1066 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1125
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPPP---GMMFPPGMPPVTAPGTPALPPTEEIWV 138
G GIPPP P PP P P +PPPP G PP PP+ G P PP + +
Sbjct: 1126 GAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGVGI 1184
Query: 139 ENKTP 143
P
Sbjct: 1185 PPPPP 1189
Score = 77.0 bits (188), Expect = 9e-14
Identities = 51/114 (44%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 967 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1026
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
G GIPPP P PP P P + +PPP PG PP PP+ G P PP
Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPP 1079
Score = 77.0 bits (188), Expect = 9e-14
Identities = 51/114 (44%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 978 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
G GIPPP P PP P P + +PPP PG PP PP+ G P PP
Sbjct: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPP 1090
Score = 76.6 bits (187), Expect = 1e-13
Identities = 50/115 (43%), Positives = 57/115 (49%), Gaps = 15/115 (13%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1114
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPPP-----GMMFPPGMPPVTAPGTPALP 131
G GIPPP P PP P P + +PPPP G+ PP +P P P LP
Sbjct: 1115 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP 1169
Score = 76.3 bits (186), Expect = 1e-13
Identities = 51/114 (44%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P A + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 956 PPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
G GIPPP P PP P P + +PPP PG PP PP+ G P PP
Sbjct: 1016 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPP 1068
Score = 75.1 bits (183), Expect = 3e-13
Identities = 50/114 (43%), Positives = 56/114 (49%), Gaps = 14/114 (12%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP-P 82
P P P + PPPL + PPPP PPPPP P G PP P +PP PP P
Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
G GIPPP P PP P P +PPP PG+ PP PP+ G P PP
Sbjct: 1159 GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP-PPPLPGAGIPPPPP 1211
Score = 74.3 bits (181), Expect = 6e-13
Identities = 46/114 (40%), Positives = 57/114 (50%), Gaps = 17/114 (14%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPP 87
P P P A + PPPL + PPPP + PPPPP P G PP PP P GIPP
Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP-----PPPLPGAGIPP 1208
Query: 88 P-----MGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEI 136
P MG P PP +PPP + +PPPP + P PP+ + PT ++
Sbjct: 1209 PPPLPGMGIPPAPAPP-LPPPGTGIPPPP--LLPVSGPPLLPQVGSSTLPTPQV 1259
Score = 72.4 bits (176), Expect = 2e-12
Identities = 51/115 (44%), Positives = 57/115 (49%), Gaps = 15/115 (13%)
Query: 32 PAPP-PNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDP----NMPPMPP- 81
P PP P A + PPPL + PPPP P PPP P G PP P +PP PP
Sbjct: 933 PLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPL 992
Query: 82 PG-GIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
PG GIPPP P PP P P + +PPP PG PP PP+ G P PP
Sbjct: 993 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPP 1046
Score = 70.5 bits (171), Expect = 8e-12
Identities = 48/115 (41%), Positives = 55/115 (47%), Gaps = 16/115 (13%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDPNMP----PMPPP- 82
P P P A + PPPL + P PP PPPPP P PP P +P P+PPP
Sbjct: 912 PPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPP-PPPLPGAGIPLPPPL 970
Query: 83 --GGIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
GIPPP P PP P P + +PPP PG PP PP+ G P PP
Sbjct: 971 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPP 1024
Score = 67.0 bits (162), Expect = 9e-11
Identities = 42/96 (43%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPG-GIP 86
P P P + PPPL + PPPP PPPPP P G PP PP+PPPG GIP
Sbjct: 1176 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA--PPLPPPGTGIP 1233
Query: 87 PPMGPPHLQRPPFMPPPMSSMPPPPGM--MFPPGMP 120
PP P + PP +P SS P P + PP +P
Sbjct: 1234 PPPLLP-VSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 66.2 bits (160), Expect = 2e-10
Identities = 45/106 (42%), Positives = 52/106 (49%), Gaps = 16/106 (15%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGP 91
P PPP ++G L PPPP PPPPP P G P +PP+ P GIPPP
Sbjct: 897 PQPPP---LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILP----LPPL-PGAGIPPPPPL 948
Query: 92 PHLQRPPFMPPPMSS----MPPP-PGMMFPPGMPPVTAPGTPALPP 132
P PP PPP+ +PPP PG PP PP+ G P PP
Sbjct: 949 PGAAIPP--PPPLPGAGIPLPPPLPGAGIPP-PPPLPGAGIPPPPP 991
Score = 66.2 bits (160), Expect = 2e-10
Identities = 48/115 (41%), Positives = 56/115 (48%), Gaps = 15/115 (13%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPF--GMMRGPPPPPRPPFGRPPFDP--NMPPMPP-P 82
P P P A + PPPL + PPPP + PPP P PP P +PP PP P
Sbjct: 1044 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1103
Query: 83 G-GIPPPMGPPHLQRPPFMPPPMSSMPPPP-----GMMFPPGMPPVTAPGTPALP 131
G GIPPP P PP P P + +PPPP G+ PP +P V P P LP
Sbjct: 1104 GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158
Score = 58.2 bits (139), Expect = 4e-08
Identities = 42/115 (36%), Positives = 50/115 (43%), Gaps = 15/115 (13%)
Query: 32 PAPPP------NAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPN--MPPMPPP- 82
P+PPP ++ M G + PPPP M P P PP +PP PPP
Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
Query: 83 --GGIPPPMGPPHLQRPPFMPPPMSSMPPP---PGMMFPPGMPPVTAPGTPALPP 132
GIPPP P P P P + +PPP PG PP PP+ G P PP
Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPP-PPPLPGAGIPLPPP 969
Score = 51.2 bits (121), Expect = 5e-06
Identities = 50/181 (27%), Positives = 64/181 (35%), Gaps = 20/181 (11%)
Query: 230 QAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTA 289
Q Q +Q + Q + + ++ SP P T +SSS P
Sbjct: 822 QGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPP 881
Query: 290 TSVAQTVSTPTTQDQTPSSAVSVATPT--VSVSTPAPTATPVQTVPQPHPQT------LP 341
TV T PS+A+ P + P P P +P P P LP
Sbjct: 882 PLPGMTVPT------LPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLP 935
Query: 342 PAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAAS 401
P +P P P P +PP PLPG IPLP LPG P P + P I
Sbjct: 936 PLPGAGIPPP----PPLPGAAIPP-PPPLPGAGIPLPPPLPGAGIPPPPPL-PGAGIPPP 989
Query: 402 P 402
P
Sbjct: 990 P 990
Score = 48.9 bits (115), Expect = 3e-05
Identities = 38/101 (37%), Positives = 44/101 (43%), Gaps = 8/101 (7%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPA-VPHSVPQPTTAIPAFPP---V 361
P + + P V P P P +P P P LP A +P P P IP PP V
Sbjct: 1092 PGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPLPGAGIPPPPPLPRV 1149
Query: 362 MVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASP 402
+PP PLPG IP P LPG P P + P V I P
Sbjct: 1150 GIPP-PPPLPGAGIPPPPPLPGAGIPPPPPL-PGVGIPPPP 1188
Score = 48.5 bits (114), Expect = 3e-05
Identities = 46/149 (30%), Positives = 62/149 (41%), Gaps = 28/149 (18%)
Query: 264 SSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPA 323
S P ++ST +S S +S + ++ P T+ S + P + + P
Sbjct: 827 SQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTES-------SSSMPGLGMVPPP 879
Query: 324 PTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPV----MVPPFRVPLPGMPIPLPG 379
P P TVP TLP +TAIP PP+ M+PP PLPG IP P
Sbjct: 880 PPPLPGMTVP-----TLP----------STAIPQPPPLQGTEMLPPPPPPLPGAGIPPPP 924
Query: 380 VLPGMAPPIVPMIHPQVAIAASPATLAGA 408
LPG I+P+ A P L GA
Sbjct: 925 PLPGAG--ILPLPPLPGAGIPPPPPLPGA 951
Score = 48.1 bits (113), Expect = 4e-05
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPA-VPHSVPQPTTAIPAFPPVMVP 364
P + + P V P P P +P P P LP A +P P P IP P +P
Sbjct: 1169 PGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP--LPGAGIPPPPPLPGMGIPPAPAPPLP 1226
Query: 365 PFRVPLPGMPIPLPGVLPGMAPPIVPMI 392
P PG IP P +LP PP++P +
Sbjct: 1227 P-----PGTGIPPPPLLPVSGPPLLPQV 1249
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/101 (35%), Positives = 43/101 (42%), Gaps = 8/101 (7%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPA-VPHSVPQPTTAIPAFPPVM-- 362
P + P P P P +P P P LP A +P P P IP PP+
Sbjct: 1103 PGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPLPRVGIPPPPPLPGA 1160
Query: 363 -VPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASP 402
+PP PLPG IP P LPG+ P P + P V I P
Sbjct: 1161 GIPP-PPPLPGAGIPPPPPLPGVGIPPPPPL-PGVGIPPPP 1199
Score = 46.2 bits (108), Expect = 2e-04
Identities = 35/101 (34%), Positives = 43/101 (42%), Gaps = 8/101 (7%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPA-VPHSVPQPTTAIPAFPPVM-- 362
P + + + P P P P +P P P LP A +P P P IP PP+
Sbjct: 960 PGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPLPGAGIPPPPPLPGA 1017
Query: 363 -VPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASP 402
+PP PLPG IP P LPG P P + P I P
Sbjct: 1018 GIPP-PPPLPGAGIPPPPPLPGAGIPPPPPL-PGAGIPPPP 1056
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/101 (34%), Positives = 43/101 (42%), Gaps = 8/101 (7%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPA-VPHSVPQPTTAIPAFPPVM-- 362
P + + P P P P +P P P LP A +P P P IP PP+
Sbjct: 1026 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPLPGAGIPPPPPLPGA 1083
Query: 363 -VPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASP 402
+PP PLPG IP P LPG+ P P + P I P
Sbjct: 1084 GIPP-PPPLPGAGIPPPPPLPGVGIPPPPPL-PGAGIPPPP 1122
Score = 45.4 bits (106), Expect = 3e-04
Identities = 32/94 (34%), Positives = 42/94 (44%), Gaps = 11/94 (11%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPA-VPHSVPQPTTAIPAFPPV--- 361
P + + P V P P P +P P P LP A +P P P IP PP+
Sbjct: 1136 PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPLPGVGIPPPPPLPGV 1193
Query: 362 -MVPPFRVPLPGMPIPLP----GVLPGMAPPIVP 390
+ PP +P G+P P P G+ P APP+ P
Sbjct: 1194 GIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP 1227
Score = 45.4 bits (106), Expect = 3e-04
Identities = 35/88 (39%), Positives = 41/88 (46%), Gaps = 18/88 (20%)
Query: 32 PAPPPNAVMRGPPPL----MRPPPPFGMMRGPPPP--PRPP--FGRPPFDPNMPPMPPPG 83
P P P + PPPL + PPPP M PP P P PP G PP PP+ P
Sbjct: 1187 PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPP-----PPLLPVS 1241
Query: 84 GIP--PPMGPPHLQRPP---FMPPPMSS 106
G P P +G L P F+PPP+ S
Sbjct: 1242 GPPLLPQVGSSTLPTPQVCGFLPPPLPS 1269
Score = 45.1 bits (105), Expect = 4e-04
Identities = 35/101 (34%), Positives = 43/101 (42%), Gaps = 8/101 (7%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPA-VPHSVPQPTTAIPAFPPVM-- 362
P + + P + P P P +P P P LP A +P P P IP PP+
Sbjct: 938 PGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPP--LPGAGIPPPPPLPGAGIPPPPPLPGA 995
Query: 363 -VPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASP 402
+PP PLPG IP P LPG P P + P I P
Sbjct: 996 GIPP-PPPLPGAGIPPPPPLPGAGIPPPPPL-PGAGIPPPP 1034
Score = 42.4 bits (98), Expect = 0.002
Identities = 71/321 (22%), Positives = 115/321 (35%), Gaps = 47/321 (14%)
Query: 115 FPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELT 174
FP +P + G P+ PP EE +E+ + + + E+ + D V Q E+
Sbjct: 618 FPRRVPSM---GPPSKPPDEEHRLEDAETESQ-----SAVSETPQKRSDAV----QKEVV 665
Query: 175 PMLA-AQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 233
M + QA V Q + + A+ + Q A A + A +A
Sbjct: 666 DMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEA 725
Query: 234 QAQAQAQAQVQAQVQAQ-VQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292
+ + + ++A+ +Q T P + + + T + +
Sbjct: 726 LRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEI 785
Query: 293 AQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPP---------A 343
+ VS Q S PT S+S P P + + + Q P + PP +
Sbjct: 786 SLIVSPRRISVQLDSHQ-----PTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTS 840
Query: 344 VPHSVP---QPTTAIPAFPPV-------------MVPPFRVPLPGMPIPLPGVLPGMAPP 387
HSV + + IP+ PP+ MVPP PLPGM +P LP A P
Sbjct: 841 HEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVP---TLPSTAIP 897
Query: 388 IVPMIHPQVAIAASPATLAGA 408
P + + P L GA
Sbjct: 898 QPPPLQGTEMLPPPPPPLPGA 918
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 5/88 (5%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHP---QTLPPAVPHSVPQPTTAIPAFP--P 360
P + P V P P P +P P P +PPA +P P T IP P P
Sbjct: 1180 PGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLP 1239
Query: 361 VMVPPFRVPLPGMPIPLPGVLPGMAPPI 388
V PP + +P P V + PP+
Sbjct: 1240 VSGPPLLPQVGSSTLPTPQVCGFLPPPL 1267
Score = 40.4 bits (93), Expect = 0.009
Identities = 27/65 (41%), Positives = 31/65 (47%), Gaps = 8/65 (12%)
Query: 31 GPAPPPNAVMRGPPPLMRPP-PPFGMMRGPPPPPRPPFGRPPFDPNM--PPMPPP---GG 84
G PPP G PP PP PP G G PPPP P PP P + +P P G
Sbjct: 1205 GIPPPPPLPGMGIPPAPAPPLPPPG--TGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGF 1262
Query: 85 IPPPM 89
+PPP+
Sbjct: 1263 LPPPL 1267
Score = 38.9 bits (89), Expect = 0.026
Identities = 43/173 (24%), Positives = 60/173 (34%), Gaps = 13/173 (7%)
Query: 190 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQV-QAQVQ 248
+ A AQ + + + + A Q + Q + Q Q Q Q Q Q+ Q Q Q
Sbjct: 164 ETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQ 223
Query: 249 AQVQAQAVGASTPTTSSPAPAVSTSTSSST--PSSTTSTTTTATSVAQTVSTPTTQDQTP 306
Q+Q A+ PT SP P PS + Q +S P
Sbjct: 224 QQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALS---ALSDLP 280
Query: 307 SSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFP 359
S A P P+P PV P +LP A P + P++ FP
Sbjct: 281 ESL--AAEPREPQQPPSPGGLPVSEAP-----SLPAAQPAAKDSPSSTAFPFP 326
Score = 31.2 bits (69), Expect = 5.5
Identities = 25/88 (28%), Positives = 29/88 (32%), Gaps = 16/88 (18%)
Query: 59 PPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPH-------------LQRPPFMPPPMS 105
PPPPP + P PP I H + PP +P S
Sbjct: 810 PPPPPSLLWSA---GQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTES 866
Query: 106 SMPPPPGMMFPPGMPPVTAPGTPALPPT 133
S P M PP PP+ P LP T
Sbjct: 867 SSSMPGLGMVPPPPPPLPGMTVPTLPST 894
>gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]
Length = 494
Score = 83.6 bits (205), Expect = 9e-16
Identities = 100/369 (27%), Positives = 142/369 (38%), Gaps = 60/369 (16%)
Query: 44 PPLMRPP-PPFGMMRGPPP--PPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQR---- 96
PP+ +P PP G PP PP P G PP P MPP+ P G+PP + H QR
Sbjct: 140 PPMAQPGLPPVPGAPGMPPGIPPLMP-GVPPLMPGMPPVMP--GMPPGL---HHQRKYTQ 193
Query: 97 ----PPFMPPPMSSMPPPPGMM-----FPPGM-PPVTAPGTPALPPTEEI---WVENKTP 143
M P MPP PG+ PPGM PPV PG P + + + + N+ P
Sbjct: 194 SFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPP 253
Query: 144 DGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQA 203
A T +P K P+ + Q+ + + A + +++
Sbjct: 254 --------APTATVPAPQPPVTK--------PLFPSAGQMGTPVTSSSTASSNSES---L 294
Query: 204 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTT 263
A ++A + AQAQA Q + A + A Q+ A ST +
Sbjct: 295 SASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNS 354
Query: 264 SSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPA 323
++ PA S TS +TTS T+ + +S + Q P + P
Sbjct: 355 TAAKPAASI-TSKPATLTTTSATSKLIHPDEDISLEERRAQLPK---------YQRNLPR 404
Query: 324 PTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLP- 382
P P+ P + P P +PQ P PP + GMP LPG +P
Sbjct: 405 PGQAPIGNPPVGPIGGMMPPQP-GIPQQQGMRPPMPP--HGQYGGHHQGMPGYLPGAMPP 461
Query: 383 -GMAPPIVP 390
G PP+VP
Sbjct: 462 YGQGPPMVP 470
Score = 48.5 bits (114), Expect = 3e-05
Identities = 42/122 (34%), Positives = 53/122 (43%), Gaps = 23/122 (18%)
Query: 11 SERFNPGE---LRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPF 67
S+ +P E L + Q +++ P P G PP+ P GMM PP+P
Sbjct: 377 SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPV---GPIGGMM-----PPQP-- 426
Query: 68 GRPPFDPNMPPMPPPG-------GIP---PPMGPPHLQRPPFMPPPMSSMPPPPGMMFPP 117
G P PPMPP G G+P P PP+ Q PP +PP P PP M PP
Sbjct: 427 GIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPP 486
Query: 118 GM 119
M
Sbjct: 487 VM 488
Score = 33.5 bits (75), Expect = 1.1
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 2/48 (4%)
Query: 349 PQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGM--APPIVPMIHP 394
PQP + P M P P+PG P PG+ P M PP++P + P
Sbjct: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPP 176
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 83.2 bits (204), Expect = 1e-15
Identities = 120/641 (18%), Positives = 272/641 (42%), Gaps = 99/641 (15%)
Query: 441 ELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKE----------------- 483
EL+E+ +++++ K+ ++E + L + + + + +K+
Sbjct: 191 ELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQ 250
Query: 484 -EPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRL---SMWDRPD 539
EP+ E T+EE +PV GT + T +RV + ++ +
Sbjct: 251 LEPQAEVFTKEENPESDGEPVVE---DGTSVKTLETLQQRVKRQENLLKRCKETIQSHKE 307
Query: 540 DLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINED 599
+ +QE ++ ++EL+K++ L + + ++ +++ + L+E++ +D
Sbjct: 308 QCTLLTSEKEALQEQLDER-LQELEKIKD-----LHMAEKTKLITQLRDAKNLIEQLEQD 361
Query: 600 EPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFST 659
+ + + KR ++ ++ ++E EI R R I + + ++ ++ + +AF
Sbjct: 362 KGMVIAETKRQMHETLEMKEE-----EIAQLRSR-IKQMTTQGEELREQKEKSERAAF-- 413
Query: 660 WEKELHKIVFDPRYLLLNPKERKQVFDQYVKT---RAEEERREKKNKIMQAKEDFKKMME 716
+EL K + + ++ K D+ +KT +EEER + ++ + K++ +M+
Sbjct: 414 --EELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMK 471
Query: 717 EAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKS 776
++ A + K + +K++ RE F E + A +K
Sbjct: 472 KSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEK-------------- 517
Query: 777 DFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEK 836
SQS + K+ + E A++ +++ E ++L E E
Sbjct: 518 ------------SQSEYLKISQEKEQQESL-ALEELELQKKAILTESENKLRDLQQEAET 564
Query: 837 ELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI--QNFKALLSDMVRSSD 894
R +E+SL + +E + + ++ E+ +H +E + + K L + D
Sbjct: 565 YRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQD 624
Query: 895 VSWSDTRRTLRKDHRWESGSLLEREEKEK---------LFNEHIEALTKKKREHFRQLLD 945
W++ + L++ ++ E L E+ E+EK +F HIE + +K E +
Sbjct: 625 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLD--VK 682
Query: 946 ETSAITLTSTWKEVKKI---IKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLL 1002
+T +L+S EV K ++E+ +K +D+ KQ E E + ++ + +++
Sbjct: 683 QTELESLSSELSEVLKARHKLEEELSVLK-DQTDKMKQ-ELEAKMDEQKNHHQQQVDSII 740
Query: 1003 KETKFITYRSKK-----------LIQESDQHLKDVEKILQN 1032
KE + R++K L++E D+HLK+ + ++N
Sbjct: 741 KEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVEN 781
Score = 59.7 bits (143), Expect = 1e-08
Identities = 123/648 (18%), Positives = 270/648 (41%), Gaps = 93/648 (14%)
Query: 433 ESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTE 492
E+ + + L+ KE+ +++ IK+ + + + ++E + +E+++ + TE
Sbjct: 368 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTE 427
Query: 493 EEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQ 552
E + KA+ DE++ T+ +L + V + +
Sbjct: 428 EARRKLKAEM-----------------DEQIKTIEKTSEEERISLQQEL---SRVKQEVV 467
Query: 553 EPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEI------NEDEPVKAKK 606
+ K E++ KL+ L+ ++ + + E+E E++ ++ E +K +
Sbjct: 468 DVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQ 527
Query: 607 RKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHK 666
K + + + E+ + I E + L+ + ++ +LE S+ EK L +
Sbjct: 528 EK-EQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILE----LESSLEKSLQE 582
Query: 667 IVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATF 726
+ L ++ + K ++ + E+ + E ++ Q + + ++ K +
Sbjct: 583 NKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEM 642
Query: 727 SEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKK--EKEDSK-TRGEKIKSDFFELL- 782
+ K ++ +KD+E +F + +K EK D K T E + S+ E+L
Sbjct: 643 EKLREKCEQEKE----TLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLK 698
Query: 783 SNHHLDSQ-----SRWSKVKDKVES------DPRYKAVDSSSMREDLFKQYIEKIAKN-- 829
+ H L+ + + K+K ++E+ + + VDS ++ Q EK K+
Sbjct: 699 ARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQI 758
Query: 830 -----LDSEKEKEL-ERQARI---EASLREREREVQKARS-------------EQTKEID 867
L E++K L E QA + EA ++ E E+Q+A + EQTK +
Sbjct: 759 NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 818
Query: 868 REREQHKREEA-IQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFN 926
+ Q +++ ++ + LL+ V + D L H+ + L+++ EK+ N
Sbjct: 819 EQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTEL-DAHKIQVQDLMQQLEKQ---N 874
Query: 927 EHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEY 986
+E K + + L++ + ++ K+I+ E I +KK+ E
Sbjct: 875 SEMEQKVKSLTQVYESKLEDGN-----KEQEQTKQILVEKENMILQMREGQKKEIE---- 925
Query: 987 IRDKYITAKADFRTLLK---ETKFITYRSKKLIQESDQHLKDVEKILQ 1031
I + ++AK D +L ETKF +K +++ Q K++++ L+
Sbjct: 926 ILTQKLSAKEDSIHILNEEYETKF--KNQEKKMEKVKQKAKEMQETLK 971
Score = 49.3 bits (116), Expect = 2e-05
Identities = 107/597 (17%), Positives = 231/597 (38%), Gaps = 83/597 (13%)
Query: 427 YNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKE--- 483
YN + E Q+L+ ++L E+ +KE E+ L +E + K E + KE
Sbjct: 1551 YNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEH 1610
Query: 484 -----EPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRP 538
+ KEEE+ E + A + ++++ M ++
Sbjct: 1611 VNLSVKSKEEELKALEDRLESESAAKLAELKR-------KAEQKIAAIKKQLLSQMEEK- 1662
Query: 539 DDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINE 598
E +KKG E H + +Q+ + + ++E+ + +E
Sbjct: 1663 --------------EEQYKKGTES-----HLSELNTKLQEREREVHILEEKLKSVESSQS 1703
Query: 599 DEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFS 658
+ + + K + ++EA + ++ E I L+ + + + +L G
Sbjct: 1704 ETLIVPRSAK--NVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEE 1761
Query: 659 TWEKELH-KIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNK-----IMQAKEDFK 712
T + + R + L E KQ DQ + +EE EK K +++
Sbjct: 1762 TVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGG 1821
Query: 713 KMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGE 772
K +AK N F + + I + K +E + + ++KE + E
Sbjct: 1822 KNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKE------LDSCLVRQKEVHRVEME 1875
Query: 773 KIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDS 832
++ S + +L + +D +++ +++ ++ + + + ++ Q+ + K +
Sbjct: 1876 ELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA 1935
Query: 833 EKEKEL--ERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMV 890
E+EK+ + R++ LR +E Q+ KE D+ERE+ ++E
Sbjct: 1936 EREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQ------------ 1983
Query: 891 RSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAI 950
++ + T + L ++ + + +E E E I + + E +ET+ +
Sbjct: 1984 EDLELKHNSTLKQLMREFNTQLAQ--KEQELEMTIKETINKAQEVEAELLESHQEETNQL 2041
Query: 951 TLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYI--RDKYITAKA-DFRTLLKE 1004
+KKI ++D ++ + +EE + R++ +TAK D +T L+E
Sbjct: 2042 --------LKKIAEKD-------DDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEE 2083
Score = 44.7 bits (104), Expect = 5e-04
Identities = 87/478 (18%), Positives = 195/478 (40%), Gaps = 56/478 (11%)
Query: 574 LSIQKWQFSMSAIKEEQE---LMEEINE-DEPVKAKKRKRDDNKDIDSEKEAAMEAEIKA 629
L IQ S A +++++ L EE+++ ++ K + +D+K +KE+ +E E+K+
Sbjct: 1463 LQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKS 1522
Query: 630 ARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYV 689
R I+ LE + Q K + +E + ++ + KE Q +
Sbjct: 1523 QTAR-IMELEDHITQ-KTIEIESLNEVLKNYNQQKD----------IEHKELVQKLQHFQ 1570
Query: 690 KTRAEEERR--EKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKD 747
+ E++ R E + KI+ + M E + + + +K+ KA+E +
Sbjct: 1571 ELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE 1630
Query: 748 REALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVES----- 802
E+ +A ++K ++ +++ S E + ++S S++ K++
Sbjct: 1631 SESAAK--LAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREV 1688
Query: 803 ---DPRYKAVDSSSMREDLFKQYIEKIAKNLDS-EKEKELERQARIEASLREREREVQKA 858
+ + K+V+SS + + + AKN+ + +++E + Q ++ + E+ +Q+
Sbjct: 1689 HILEEKLKSVESSQSETLI----VPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRN 1744
Query: 859 RSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLER 918
+E+ K + R Q K E +F+ R + ++ ++ +D E
Sbjct: 1745 LTEKEKLLQRV-GQEKEETVSSHFEMRCQYQERLIKLEHAEAKQ--HEDQSMIGHLQEEL 1801
Query: 919 EEKEKLFN----EHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSS 974
EEK K ++ +H+E K +Q L + + +V+K ++E +
Sbjct: 1802 EEKNKKYSLIVAQHVEKEGGKNNIQAKQ--------NLENVFDDVQKTLQEKELTCQILE 1853
Query: 975 SDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQN 1032
K+ D + + + + E Y + +Q+ D K E + +N
Sbjct: 1854 QKIKE--------LDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEEN 1903
Score = 42.7 bits (99), Expect = 0.002
Identities = 84/440 (19%), Positives = 182/440 (41%), Gaps = 50/440 (11%)
Query: 582 SMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEAR 641
S+ + EE E + N+++ ++ K+K + ++ +K EA++K E + L +
Sbjct: 937 SIHILNEEYETKFK-NQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQK 995
Query: 642 MKQFKDMLLER----------GVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKT 691
KQF +LE VS T +KE + + + LN + ++++ +
Sbjct: 996 EKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELN--DVISIWEKKLNQ 1053
Query: 692 RAEE-------ERREKKNKIMQAKEDFKKM-MEEAKFNPRATFSEFAAKHAKDSRFKAIE 743
+AEE + +EK+ ++ + K+ E+ + N T+ + + + E
Sbjct: 1054 QAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQE 1113
Query: 744 KMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESD 803
++K + A N +++ K EK++ D + L + Q + ++K E D
Sbjct: 1114 QLKQKSAHVNSLA-----QDETKLKAHLEKLEVDLNKSLKENTF-LQEQLVELKMLAEED 1167
Query: 804 PRYKAVDSSSMR--EDLFKQYIEKIAKNLDSEKEKELERQ--------------ARIEAS 847
R + +S ++ ++ F+ K+ S ++K LE + + EA
Sbjct: 1168 KRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEAL 1227
Query: 848 LREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDV-----SWSDTRR 902
L + E+ S +T I R H + + +ALL S++ ++ +
Sbjct: 1228 LEAKTNELINISSSKTNAI-LSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQN 1286
Query: 903 TLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAIT-LTSTWKEVKK 961
TL + + L E+E + K IE+L +K ++ ++ A + S ++KK
Sbjct: 1287 TLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKK 1346
Query: 962 IIKEDPRCIKFSSSDRKKQR 981
+ E+ + + K+++
Sbjct: 1347 ELSENINAVTLMKEELKEKK 1366
Score = 36.2 bits (82), Expect = 0.17
Identities = 47/278 (16%), Positives = 121/278 (43%), Gaps = 16/278 (5%)
Query: 696 ERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEF 755
+R +KK + + ++ K + A+ + A KH ++ ++E+ ++
Sbjct: 168 QREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQ 227
Query: 756 VAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMR 815
V+ +++ R + D + L L+ Q+ ++ ESD D +S++
Sbjct: 228 VSLLKQR------LRNGPMNVDVLKPLPQ--LEPQAEVFTKEENPESDGEPVVEDGTSVK 279
Query: 816 EDLFKQYIEKIAKNLDSEKEKELERQARIEASLRERERE-VQKARSEQTKEIDREREQHK 874
Q K +NL ++ KE + + + +L E+E +Q+ E+ +E+++ ++ H
Sbjct: 280 TLETLQQRVKRQENL-LKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHM 338
Query: 875 REEA-----IQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHI 929
E+ +++ K L+ + + + ++T+R + + + + + + K
Sbjct: 339 AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQG 398
Query: 930 EALTKKKREHFRQLLDE-TSAITLTSTWKEVKKIIKED 966
E L ++K + R +E A++ +E ++ +K +
Sbjct: 399 EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAE 436
Score = 35.0 bits (79), Expect = 0.38
Identities = 78/381 (20%), Positives = 163/381 (42%), Gaps = 60/381 (15%)
Query: 617 SEKEAAMEAEIKAARERAIVPLE-ARMKQFK-DMLLERGVSA----------FSTWEKEL 664
SEKEAA+ + K E L+ + FK D L + +SA FS W+K+
Sbjct: 1390 SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKA 1449
Query: 665 HKIVFDPR--------YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAK-EDFKKMM 715
+ L L KE + +Q + E +++ K+ ++ + ED K M
Sbjct: 1450 QSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKM 1509
Query: 716 EEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIK 775
E+ + N A+ + +K + E+L NE + +++ + K +K++
Sbjct: 1510 EKKESNLETELKSQTAR-IMELEDHITQKTIEIESL-NEVLKNYNQQKDIEHKELVQKLQ 1567
Query: 776 --SDFFELLSNHHLDSQSRWSKVKDKV-----ESDPRYKAVDSSSMREDLFKQYIEKIAK 828
+ E N +++ + ++++V E + + K ++ ++ ++ ++ +
Sbjct: 1568 HFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALED 1627
Query: 829 NLDSE---KEKELERQA---------RIEASLREREREVQKARSEQTKEI-----DRERE 871
L+SE K EL+R+A ++ + + E+E + +K E+ +RERE
Sbjct: 1628 RLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERERE 1687
Query: 872 QHKREEAIQNFKALLSD----------MVRSSDVSWSDTRRTLRKDHRWESGSLLERE-- 919
H EE +++ ++ S+ + ++ +D++ ++K + E S+L+R
Sbjct: 1688 VHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYE-EKISVLQRNLT 1746
Query: 920 EKEKLFNEHIEALTKKKREHF 940
EKEKL + + HF
Sbjct: 1747 EKEKLLQRVGQEKEETVSSHF 1767
>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
Length = 898
Score = 81.3 bits (199), Expect = 5e-15
Identities = 101/382 (26%), Positives = 136/382 (35%), Gaps = 52/382 (13%)
Query: 42 GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96
GPPP+ P P F + R P R P D + MP PP G
Sbjct: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 220
Query: 97 PPFMPPPMSSMPPPPGMMF------PPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150
P P +PP P + P P A PA K P G++
Sbjct: 221 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK 280
Query: 151 ---NARTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQ-----AQAQAQAQ 196
AR T+ PD + ++++ P +L QAQVQ+Q Q Q Q +
Sbjct: 281 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
Query: 197 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV 256
Q QAQ Q + Q Q Q Q Q +A+ Q Q Q Q Q QA +Q QVQ Q +A+ +
Sbjct: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
Query: 257 GASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPT 316
P V S P Q Q QT + A P+
Sbjct: 401 -------KQVQPQVQPQAHSQPPRQ-----------VQLQLQKQVQTQTYPQVHTQAQPS 442
Query: 317 VSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIP 376
V P VQ Q H Q PH+ PQ + P PV+V + +P +
Sbjct: 443 VQPQEHPPAQVSVQPPEQTHEQ------PHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 496
Query: 377 LPGVLPGMAPPIVPMIHPQVAI 398
G GM + + QV++
Sbjct: 497 AGG---GMEKTLPEPVGTQVSM 515
Score = 70.1 bits (170), Expect = 1e-11
Identities = 82/297 (27%), Positives = 107/297 (36%), Gaps = 51/297 (17%)
Query: 22 AQQQALRFRGPAPPPNAVMRGPPPLMR-------PPPPFGMM---RGPPPPPRP------ 65
+ Q + + PP P M PP P + R P P P P
Sbjct: 198 SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASEL 257
Query: 66 PFGRPPFDPNMPPMPPPGGIP---PPMG----PPHLQRPPFMPPPMSSMPPPPGMMFPPG 118
P R PPG + P P Q P +P + + P F P
Sbjct: 258 PAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP---RFQPR 314
Query: 119 MPPVTAP----GTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELT 174
+ V A P +P T+ V+ K A+T+ T P+ + V+QQ ++
Sbjct: 315 VLQVQAQVQSQTQPRIPSTDT-QVQPKLQK------QAQTQ----TSPEHL-VLQQKQVQ 362
Query: 175 PMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQA----QAQAQAQAQAQAQAQAQAQAQ 230
P L +A+ Q Q Q Q Q QA +Q Q Q Q +A Q Q Q Q QA +Q Q Q Q
Sbjct: 363 PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ 422
Query: 231 AQAQAQAQAQAQVQAQVQAQVQAQ-----AVGASTPTTSSPAPAVSTSTSSSTPSST 282
Q Q Q Q QV Q Q VQ Q V P + P S P T
Sbjct: 423 LQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 479
Score = 47.0 bits (110), Expect = 1e-04
Identities = 86/442 (19%), Positives = 134/442 (30%), Gaps = 59/442 (13%)
Query: 10 ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPR----- 64
+ ++ +L QQ + AP P AV RG PP +P P ++G
Sbjct: 26 QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84
Query: 65 -------------PPFGRPP--FDPNMPPMPPP--------GGIPPPMGPPHLQRPPFMP 101
F PP +D MP G P + P L P
Sbjct: 85 LQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLAT 144
Query: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPAL-------PPTEEIWVENKTPDGKVYYYNART 154
P + P G PPV P P+ P + + TP+ K
Sbjct: 145 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 204
Query: 155 RESAWTKPDGVKVIQQSEL-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQ 212
E P+G + + + TP + + A +A + A+
Sbjct: 205 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
Query: 213 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVST 272
++ + + Q Q +AQ QA+ Q Q + ++AQ + P V +
Sbjct: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
Query: 273 STSSSTPSSTTSTTTTATSVAQTVSTP----TTQDQTPSSAVSVATPTVSVS-------- 320
T PS+ T AQT ++P Q Q A P V
Sbjct: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
Query: 321 TPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGV 380
+ P +Q +P Q P P + QP + ++ P V
Sbjct: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQV---------QLQLQKQVQTQTYPQV 435
Query: 381 LPGMAPPIVPMIHPQVAIAASP 402
P + P HP ++ P
Sbjct: 436 HTQAQPSVQPQEHPPAQVSVQP 457
Score = 40.0 bits (92), Expect = 0.012
Identities = 77/311 (24%), Positives = 106/311 (34%), Gaps = 44/311 (14%)
Query: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277
Q Q Q Q Q Q Q Q Q Q Q+Q Q Q+Q Q + S P P AVS
Sbjct: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62
Query: 278 TP-------SSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVAT-PTVSVSTPAPTATPV 329
P T S + S+ Q A+ AT T ++ P T +
Sbjct: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNL 122
Query: 330 QTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIV 389
+ P P S+ P A P R L G P P V
Sbjct: 123 RGYGMASPGLAAP----SLTPPQLATPNLQQFFPQATRQSLLGPP-----------PVGV 167
Query: 390 PMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRT-----LESTWEKPQELKE 444
PM Q ++ T+ S K + +T +++ E E + E
Sbjct: 168 PMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE 227
Query: 445 KEKL---EEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQ--- 498
+ L E I + + P+ EP P E E P K ++ EE TE+E Q
Sbjct: 228 DQDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEKEPPGQLQV 279
Query: 499 KAKPVATAPIP 509
KA+P A +P
Sbjct: 280 KAQPQARMTVP 290
>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
Length = 898
Score = 81.3 bits (199), Expect = 5e-15
Identities = 101/382 (26%), Positives = 136/382 (35%), Gaps = 52/382 (13%)
Query: 42 GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96
GPPP+ P P F + R P R P D + MP PP G
Sbjct: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 220
Query: 97 PPFMPPPMSSMPPPPGMMF------PPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150
P P +PP P + P P A PA K P G++
Sbjct: 221 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK 280
Query: 151 ---NARTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQ-----AQAQAQAQ 196
AR T+ PD + ++++ P +L QAQVQ+Q Q Q Q +
Sbjct: 281 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
Query: 197 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV 256
Q QAQ Q + Q Q Q Q Q +A+ Q Q Q Q Q QA +Q QVQ Q +A+ +
Sbjct: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
Query: 257 GASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPT 316
P V S P Q Q QT + A P+
Sbjct: 401 -------KQVQPQVQPQAHSQPPRQ-----------VQLQLQKQVQTQTYPQVHTQAQPS 442
Query: 317 VSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIP 376
V P VQ Q H Q PH+ PQ + P PV+V + +P +
Sbjct: 443 VQPQEHPPAQVSVQPPEQTHEQ------PHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 496
Query: 377 LPGVLPGMAPPIVPMIHPQVAI 398
G GM + + QV++
Sbjct: 497 AGG---GMEKTLPEPVGTQVSM 515
Score = 70.1 bits (170), Expect = 1e-11
Identities = 82/297 (27%), Positives = 107/297 (36%), Gaps = 51/297 (17%)
Query: 22 AQQQALRFRGPAPPPNAVMRGPPPLMR-------PPPPFGMM---RGPPPPPRP------ 65
+ Q + + PP P M PP P + R P P P P
Sbjct: 198 SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASEL 257
Query: 66 PFGRPPFDPNMPPMPPPGGIP---PPMG----PPHLQRPPFMPPPMSSMPPPPGMMFPPG 118
P R PPG + P P Q P +P + + P F P
Sbjct: 258 PAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP---RFQPR 314
Query: 119 MPPVTAP----GTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELT 174
+ V A P +P T+ V+ K A+T+ T P+ + V+QQ ++
Sbjct: 315 VLQVQAQVQSQTQPRIPSTDT-QVQPKLQK------QAQTQ----TSPEHL-VLQQKQVQ 362
Query: 175 PMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQA----QAQAQAQAQAQAQAQAQAQAQ 230
P L +A+ Q Q Q Q Q QA +Q Q Q Q +A Q Q Q Q QA +Q Q Q Q
Sbjct: 363 PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ 422
Query: 231 AQAQAQAQAQAQVQAQVQAQVQAQ-----AVGASTPTTSSPAPAVSTSTSSSTPSST 282
Q Q Q Q QV Q Q VQ Q V P + P S P T
Sbjct: 423 LQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 479
Score = 47.0 bits (110), Expect = 1e-04
Identities = 86/442 (19%), Positives = 134/442 (30%), Gaps = 59/442 (13%)
Query: 10 ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPR----- 64
+ ++ +L QQ + AP P AV RG PP +P P ++G
Sbjct: 26 QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84
Query: 65 -------------PPFGRPP--FDPNMPPMPPP--------GGIPPPMGPPHLQRPPFMP 101
F PP +D MP G P + P L P
Sbjct: 85 LQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLAT 144
Query: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPAL-------PPTEEIWVENKTPDGKVYYYNART 154
P + P G PPV P P+ P + + TP+ K
Sbjct: 145 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 204
Query: 155 RESAWTKPDGVKVIQQSEL-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQ 212
E P+G + + + TP + + A +A + A+
Sbjct: 205 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
Query: 213 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVST 272
++ + + Q Q +AQ QA+ Q Q + ++AQ + P V +
Sbjct: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
Query: 273 STSSSTPSSTTSTTTTATSVAQTVSTP----TTQDQTPSSAVSVATPTVSVS-------- 320
T PS+ T AQT ++P Q Q A P V
Sbjct: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
Query: 321 TPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGV 380
+ P +Q +P Q P P + QP + ++ P V
Sbjct: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQV---------QLQLQKQVQTQTYPQV 435
Query: 381 LPGMAPPIVPMIHPQVAIAASP 402
P + P HP ++ P
Sbjct: 436 HTQAQPSVQPQEHPPAQVSVQP 457
Score = 40.0 bits (92), Expect = 0.012
Identities = 77/311 (24%), Positives = 106/311 (34%), Gaps = 44/311 (14%)
Query: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277
Q Q Q Q Q Q Q Q Q Q Q+Q Q Q+Q Q + S P P AVS
Sbjct: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62
Query: 278 TP-------SSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVAT-PTVSVSTPAPTATPV 329
P T S + S+ Q A+ AT T ++ P T +
Sbjct: 63 QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNL 122
Query: 330 QTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIV 389
+ P P S+ P A P R L G P P V
Sbjct: 123 RGYGMASPGLAAP----SLTPPQLATPNLQQFFPQATRQSLLGPP-----------PVGV 167
Query: 390 PMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRT-----LESTWEKPQELKE 444
PM Q ++ T+ S K + +T +++ E E + E
Sbjct: 168 PMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE 227
Query: 445 KEKL---EEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQ--- 498
+ L E I + + P+ EP P E E P K ++ EE TE+E Q
Sbjct: 228 DQDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEKEPPGQLQV 279
Query: 499 KAKPVATAPIP 509
KA+P A +P
Sbjct: 280 KAQPQARMTVP 290
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 80.5 bits (197), Expect = 8e-15
Identities = 51/119 (42%), Positives = 58/119 (48%), Gaps = 17/119 (14%)
Query: 33 APPPNAVMRGPPPLMRPPPPFGMMR-GP----PPPPRPPFGRPPFDP--NMPPMPPPGGI 85
A PPN R PPP++ P PFG GP PPPP P +G PP P P PPPG
Sbjct: 264 AGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPF 323
Query: 86 PP----PMGPP-HLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPAL-----PPTE 134
PP P+GPP L PP +P P PPP + P PP T G P PPT+
Sbjct: 324 PPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTD 382
Score = 73.2 bits (178), Expect = 1e-12
Identities = 61/145 (42%), Positives = 67/145 (46%), Gaps = 39/145 (26%)
Query: 28 RFRGPA-----PPPNAVMRGPP--PLMRP-------PPPFGMM----------RG--PPP 61
RF GPA PPP + PP PL P PPP G + RG PPP
Sbjct: 216 RFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPP 275
Query: 62 P---PRPPFGRPPFDPNMPPMPP---PGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMF 115
P P PFG+PP P +PP PP PG PPP PP Q PP PPP P PPG +
Sbjct: 276 PVLFPGQPFGQPPLGP-LPPGPPPPVPGYGPPPGPPPPQQGPP--PPPGPFPPRPPGPLG 332
Query: 116 PP--GMPPVTAPGTP--ALPPTEEI 136
PP PP PG P A PP +
Sbjct: 333 PPLTLAPPPHLPGPPPGAPPPAPHV 357
Score = 69.3 bits (168), Expect = 2e-11
Identities = 53/125 (42%), Positives = 58/125 (46%), Gaps = 31/125 (24%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRG--PPPP---PRPPFGRPPFDPNMPPMPPPG-- 83
GP PPP V+ PPPL PP RG PPPP P PFG+PP P +PP PPP
Sbjct: 251 GP-PPPGQVL--PPPLAGPPN-----RGDRPPPPVLFPGQPFGQPPLGP-LPPGPPPPVP 301
Query: 84 ------GIPPPMGPPHLQRPPFMP-------PPMSSMPPPPGMMFPPGMPPVTAPGTPAL 130
G PPP P PF P PP++ PPP PPG PP PA
Sbjct: 302 GYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAF 361
Query: 131 --PPT 133
PPT
Sbjct: 362 FPPPT 366
Score = 50.1 bits (118), Expect = 1e-05
Identities = 45/125 (36%), Positives = 53/125 (42%), Gaps = 20/125 (16%)
Query: 31 GPAPPPNAVMRGPPPLM-----RPPPPFG---MMRGPPPPPRPPFGRPPFDPNMPP--MP 80
GP P P +GPPP RPP P G + PP P PP G PP P++ P P
Sbjct: 304 GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFP 363
Query: 81 PP--GGIP--PPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEI 136
PP G+P GPP P+ PP P G PPG TA + EEI
Sbjct: 364 PPTNSGMPTSDSRGPP--PTDPYGRPP----PYDRGDYGPPGREMDTARTPLSEAEFEEI 417
Query: 137 WVENK 141
N+
Sbjct: 418 MNRNR 422
Score = 40.8 bits (94), Expect = 0.007
Identities = 26/73 (35%), Positives = 27/73 (36%), Gaps = 6/73 (8%)
Query: 315 PTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMP 374
P V P P P Q P P P PP P + P T P P P PG P
Sbjct: 298 PPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP------PHLPGPPPGAP 351
Query: 375 IPLPGVLPGMAPP 387
P P V P PP
Sbjct: 352 PPAPHVNPAFFPP 364
Score = 38.1 bits (87), Expect = 0.045
Identities = 30/84 (35%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 322 PAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPL--PG 379
P P A P +P P L P P P P +P PP VP + P PG P P P
Sbjct: 260 PPPLAGPPNRGDRPPPPVLFPGQPFGQP-PLGPLPPGPPPPVPGYGPP-PGPPPPQQGPP 317
Query: 380 VLPGMAPPIVP-MIHPQVAIAASP 402
PG PP P + P + +A P
Sbjct: 318 PPPGPFPPRPPGPLGPPLTLAPPP 341
Score = 37.0 bits (84), Expect = 0.10
Identities = 31/87 (35%), Positives = 33/87 (37%), Gaps = 15/87 (17%)
Query: 322 PAPTATPVQTVPQPHPQTLPPAVPHSVPQ-------------PTTAIPAFPPVMVPPFRV 368
P P P Q QP LPP P VP P FPP P
Sbjct: 274 PPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGP 333
Query: 369 PLPGMPIP-LPGVLPGMAPPIVPMIHP 394
PL P P LPG PG APP P ++P
Sbjct: 334 PLTLAPPPHLPGPPPG-APPPAPHVNP 359
Score = 35.0 bits (79), Expect = 0.38
Identities = 29/82 (35%), Positives = 32/82 (39%), Gaps = 11/82 (13%)
Query: 322 PAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFR-------VPLPGMP 374
P P QT P+P P P P P +P PP+ PP R V PG P
Sbjct: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLP--PPLAGPPNRGDRPPPPVLFPGQP 283
Query: 375 IPLP--GVLPGMAPPIVPMIHP 394
P G LP PP VP P
Sbjct: 284 FGQPPLGPLPPGPPPPVPGYGP 305
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 80.5 bits (197), Expect = 8e-15
Identities = 51/114 (44%), Positives = 55/114 (48%), Gaps = 22/114 (19%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGR-----PPFDPNMPPMPPPGGI 85
G APPP PPP PPPP M+ PPPPP FG PP P+ PP P
Sbjct: 315 GFAPPP-----APPP---PPPP--MIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAP 364
Query: 86 PPPMGPPHLQRPPFMPPPMS----SMPPPPGMMFPPGMPP---VTAPGTPALPP 132
PPP PP P PPP+S PPPP PPG PP A G PA+PP
Sbjct: 365 PPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPP 418
Score = 71.6 bits (174), Expect = 4e-12
Identities = 46/112 (41%), Positives = 49/112 (43%), Gaps = 14/112 (12%)
Query: 32 PAPPPNAVMRGP-----PPLMRPPPPFGMMRGPPPPPRPPFGRP-----PFDPNMPPMPP 81
P PP GP PP PPPP M+ PPPPP FG P P P+ PP P
Sbjct: 301 PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD 360
Query: 82 PGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPT 133
PPP PP P PPP+S P G PP PP PG P P T
Sbjct: 361 FAAPPPPPPPPAADYPTLPPPPLSQ--PTGGA--PPPPPPPPPPGPPPPPFT 408
Score = 68.2 bits (165), Expect = 4e-11
Identities = 39/84 (46%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Query: 50 PPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPM-SSMP 108
PPP + G PP P+P F PP P PP PP GIPPP P P PPP S P
Sbjct: 300 PPPAPPL-GSPPGPKPGFAPPPAPP--PPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFP 356
Query: 109 PPPGMMFPPGMPPVTAPGTPALPP 132
P P PP PP A P LPP
Sbjct: 357 PHPDFAAPPPPPPPPAADYPTLPP 380
Score = 58.2 bits (139), Expect = 4e-08
Identities = 46/110 (41%), Positives = 50/110 (45%), Gaps = 19/110 (17%)
Query: 28 RFRGPAPPPNAVMRGP--PPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGI 85
R G A P + + P PP P PP G PP P+P F PP P PP PP GI
Sbjct: 282 RGSGLAGPKRSSVVSPSHPP---PAPPLGS----PPGPKPGFAPPPAPP--PPPPPMIGI 332
Query: 86 PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEE 135
PPP PP P PPP P PP FPP P AP P PP +
Sbjct: 333 PPPP-PPVGFGSPGTPPP----PSPPS--FPPH-PDFAAPPPPPPPPAAD 374
Score = 56.6 bits (135), Expect = 1e-07
Identities = 43/127 (33%), Positives = 47/127 (37%), Gaps = 42/127 (33%)
Query: 32 PAPPPNAVMRGPPPLMR----PPPPFGM-----------MRGPP---------PPPRPPF 67
P PP + P P PPPP + GP PPP PP
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
Query: 68 GRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGM--MFPPGMPPVTAP 125
G PP P PG PPP PP PPPM +PPPP PG PP P
Sbjct: 307 GSPPG-------PKPGFAPPPAPPPP-------PPPMIGIPPPPPPVGFGSPGTPP--PP 350
Query: 126 GTPALPP 132
P+ PP
Sbjct: 351 SPPSFPP 357
Score = 52.8 bits (125), Expect = 2e-06
Identities = 32/81 (39%), Positives = 37/81 (45%), Gaps = 9/81 (11%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPP--RPPFGRPPFDPNMPPMPPPGGIPPPM 89
P+ PP+ PPP PPPP PPPP +P G PP PP PPP PPP
Sbjct: 353 PSFPPHPDFAAPPP--PPPPPAADYPTLPPPPLSQPTGGAPP-----PPPPPPPPGPPPP 405
Query: 90 GPPHLQRPPFMPPPMSSMPPP 110
P +PPP+S P
Sbjct: 406 PFTGADGQPAIPPPLSDTTKP 426
Score = 47.4 bits (111), Expect = 7e-05
Identities = 45/151 (29%), Positives = 57/151 (37%), Gaps = 14/151 (9%)
Query: 252 QAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVS 311
Q ++G +S P S S+S+PS + S A+ S P + A
Sbjct: 231 QNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAE-FSYPVDNQRGSGLAGP 289
Query: 312 VATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP 371
+ VS S P P A P+ + P P P PP P P P IP P PP P
Sbjct: 290 KRSSVVSPSHPPP-APPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPP----PPVGFGSP 344
Query: 372 GMPIPLPGVLPGMAPPIVPMIHPQVAIAASP 402
G P P +PP P HP A P
Sbjct: 345 GTP-------PPPSPPSFPP-HPDFAAPPPP 367
Score = 38.9 bits (89), Expect = 0.026
Identities = 27/91 (29%), Positives = 31/91 (34%), Gaps = 7/91 (7%)
Query: 299 PTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQ--PHPQTLPPAVPHSVPQPTTAIP 356
P P + + P V +P P + P PHP P P P P P
Sbjct: 319 PPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAP--PPPPPPPAADYP 376
Query: 357 AFPPVMVPPFRVPLPGMPIPLPGVLPGMAPP 387
PP PP P G P P P P PP
Sbjct: 377 TLPP---PPLSQPTGGAPPPPPPPPPPGPPP 404
Score = 32.0 bits (71), Expect = 3.2
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 15/104 (14%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAV------PHSVPQPTTAIPAFP 359
P V +P P+ P P P PPA P + QPT P P
Sbjct: 335 PPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPP 394
Query: 360 PVMVPPFRVPLPG-MPIPLPGV--LPGMAPPIVPMIHPQVAIAA 400
P PP P PG P P G P + PP+ P+ ++ A
Sbjct: 395 P---PP---PPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPA 432
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 77.8 bits (190), Expect = 5e-14
Identities = 49/123 (39%), Positives = 58/123 (47%), Gaps = 19/123 (15%)
Query: 23 QQQALRFRGPAPPPNAVMRGPPPL------MRPPPPF-----GMMRGPPPPPRPPFGRPP 71
QQ+AL PPP A + PPPL + P PP G PPPPP PP PP
Sbjct: 641 QQKAL------PPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPL-PPP 693
Query: 72 FDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMS-SMPPPPGMMFPPGMPPVTAPGTPAL 130
PP PPP +P PP+ PP PPP + PPPPG+ F G P PA+
Sbjct: 694 SSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAI 753
Query: 131 PPT 133
P+
Sbjct: 754 EPS 756
Score = 45.8 bits (107), Expect = 2e-04
Identities = 46/169 (27%), Positives = 70/169 (41%), Gaps = 22/169 (13%)
Query: 321 TPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPF----RVPLPGMPIP 376
+PAP PV P P PP P +P P++A P PP PP P PG P P
Sbjct: 666 SPAPPMPPVSAGPPLPP---PPPPPPPLPPPSSAGPP-PPPPPPPLPNSPAPPNPGGPPP 721
Query: 377 LPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTW 436
P PG+APP P + + +S + A+ K ++R+ +T
Sbjct: 722 APPP-PGLAPPPPPGLF--FGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQISDRSQNAT- 777
Query: 437 EKPQELKEKEKLEEKIKEP-IKEPSEEPLPMETEEEDPKEEPIKEIKEE 484
L + ++EP I++PSE + K++P+ E E+
Sbjct: 778 ---------PTLWDSLEEPDIRDPSEFEYLFSKDTTQQKKKPLSETYEK 817
Score = 36.6 bits (83), Expect = 0.13
Identities = 43/180 (23%), Positives = 68/180 (37%), Gaps = 29/180 (16%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPP 365
P VS P P P P + P P PP +P+S P P PP PP
Sbjct: 670 PMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPP-PPPLPNSPAPPN---PGGPPPAPPP 725
Query: 366 FRVPLPGM-PIPLPGVLPGMAP-----PIVPMIHPQVAIAASPATLAGATAVSEWTEYKT 419
PG+ P P PG+ G+ P P I P + WT +
Sbjct: 726 -----PGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP-----------LYWTRIQI 769
Query: 420 ADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIK 479
+D TL + E+P ++++ + E + + ++PL E+++ ++ IK
Sbjct: 770 SDRS--QNATPTLWDSLEEP-DIRDPSEFEYLFSKDTTQQKKKPLSETYEKKNKVKKIIK 826
Score = 35.4 bits (80), Expect = 0.29
Identities = 23/54 (42%), Positives = 27/54 (50%), Gaps = 7/54 (12%)
Query: 85 IPPPMGPPHLQRPPFMPPPMSSMPPPP-----GMMFP-PGMPPVTAPGTPALPP 132
+ P G Q+ PPP S PPPP G + P P MPPV+A G P PP
Sbjct: 631 LQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSA-GPPLPPP 683
Score = 32.0 bits (71), Expect = 3.2
Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 12/89 (13%)
Query: 328 PVQTVPQPHPQTLPPAVPHSVPQPT---------TAIPAFPPVMVPPFRVPLPGMPIPLP 378
P++ + + LPP P S+P P + P PPV P P P P PLP
Sbjct: 633 PMEGMASNQQKALPPP-PASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLP 691
Query: 379 GVLPGMAPPIVPMIHPQVAIAASPATLAG 407
P A P P P + + +P G
Sbjct: 692 P--PSSAGPPPPPPPPPLPNSPAPPNPGG 718
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 77.4 bits (189), Expect = 7e-14
Identities = 48/107 (44%), Positives = 53/107 (49%), Gaps = 15/107 (14%)
Query: 16 PGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPN 75
PG +A L P PPP G PPL PPPP PPPPP+P F PP P
Sbjct: 664 PGAAAVAAPSVLAPTLPLPPPP----GFPPL--PPPP------PPPPPQPGFPMPPPLPP 711
Query: 76 MPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPV 122
PP PPP + PP L PP +PPP P PP FPPG+ PV
Sbjct: 712 PPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPP---FPPGLFPV 755
Score = 68.9 bits (167), Expect = 2e-11
Identities = 105/426 (24%), Positives = 145/426 (34%), Gaps = 58/426 (13%)
Query: 5 GGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGP------PPLMRPPPPFGMMRG 58
GG GG S G AQ Q PPP P P P F
Sbjct: 358 GGTGGSS-----GPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHF----- 407
Query: 59 PPPPPRPP------------FGRPPFDPNMPPMPPPGGIPP--PMGPPHLQRPPFMPPPM 104
PPPP P F R P P +PP P P P GPP PP
Sbjct: 408 PPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPP--------PPDT 459
Query: 105 SSMPPPPGMMFPPGMPPVTAPGTPAL---PPTEEIWVENKTPDGKVYYYNARTRESAWTK 161
+SM F P +PGTP L P E ++ ++ RT+ +
Sbjct: 460 NSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLRE 519
Query: 162 PDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 221
PD +Q E +P+ ++ +Q+ A +Q + ++ +
Sbjct: 520 PDSDTELQM-EGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLP 578
Query: 222 QAQAQAQAQAQAQAQAQAQ------AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTS 275
+ + + + A + +Q A+V VG TPT+ +S
Sbjct: 579 DSDEDEELDLGLGPRPPPEPGPPDPAGLLSQT-AEVALDLVGDRTPTSEKMDEGQQSSGE 637
Query: 276 SSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPA--PTATPVQTVP 333
S + TS T +A SV PT+ + P P P P
Sbjct: 638 DMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPP 697
Query: 334 QPHPQ-TLPPAVPHSVPQPTTAIPAF----PPVMVPPFRVPLPGMPIPLPGVLPGMAPPI 388
P P +PP +P P P A PA PP+ PP P P +P PLP PG+ P +
Sbjct: 698 PPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILP-PLPPFPPGLFPVM 756
Query: 389 -VPMIH 393
V M H
Sbjct: 757 QVDMSH 762
Score = 55.1 bits (131), Expect = 4e-07
Identities = 94/414 (22%), Positives = 133/414 (32%), Gaps = 69/414 (16%)
Query: 52 PFGMMRGPPPPPRPPFGRPPFD-PNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPP 110
PFG + G PPF P D PPP P G P P++ PPP
Sbjct: 353 PFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSP--YQTPVAHFPPP 410
Query: 111 P------------------GMMFPPGMPPV-----TAPGTPALPP---TEEIWVENKTPD 144
P PP +PP PGTP PP T + + +
Sbjct: 411 PEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTF 470
Query: 145 G----KVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQV-----QAQAQAQAQAQA 195
G T ES+ P+ S + +L Q + + + Q +
Sbjct: 471 GWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEG 530
Query: 196 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQA 255
+ + +Q A +Q + ++ + + ++
Sbjct: 531 SPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGL 590
Query: 256 VGASTPTTSSPAPAVSTSTSSS---------TPSS-------TTSTTTTATSVAQTVSTP 299
P P PA S ++ TP+S +S S + S P
Sbjct: 591 GPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAP 650
Query: 300 TTQDQTPS------SAVSVATPTVSVST---PAPTATPVQTVPQPHPQTLP--PAVPHSV 348
T P A +VA P+V T P P P P P P P P P
Sbjct: 651 ITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLP 710
Query: 349 PQPTTAIPAFPPVMVPPFRVPLPGMP-IPLPGVLPGMAPPIVPMIHPQVAIAAS 401
P P PA P V VPP PLP P +P P +LP + PP P + P + + S
Sbjct: 711 PPPPPPPPAHPAVTVPP--PPLPAPPGVPPPPILPPL-PPFPPGLFPVMQVDMS 761
Score = 45.4 bits (106), Expect = 3e-04
Identities = 43/152 (28%), Positives = 53/152 (34%), Gaps = 40/152 (26%)
Query: 9 GESERFNPG-----ELRMAQQQALRFRGPAPPPNAVMRGPPPL----------MRPPPPF 53
GE PG L M ++ + AP M PPL PP
Sbjct: 1170 GEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEP 1229
Query: 54 G------MMRGPPPPPRPPFGRPPFDPNMPPM-------PPPGGIPPPMGPPHLQRPPFM 100
G M+ P PP + RPP P P PP +P P+ PP +
Sbjct: 1230 GLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPP-------L 1282
Query: 101 PPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
PPP P PP PP P T P++PP
Sbjct: 1283 PPPR--PPRPPS---PPPEPETTDASHPSVPP 1309
Score = 45.1 bits (105), Expect = 4e-04
Identities = 37/126 (29%), Positives = 46/126 (36%), Gaps = 16/126 (12%)
Query: 16 PGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPN 75
P E ++Q+ A+ P PP V PP P + P PP P P
Sbjct: 1226 PEEPGLSQEGAMLL-SPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPL------PL 1278
Query: 76 MPPMPPPGGIPPPMGPPH-----LQRPPFMPPPMSSMPPP--PGM--MFPPGMPPVTAPG 126
PP+PPP PP PP P P P++ PP PG+ T P
Sbjct: 1279 QPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPA 1338
Query: 127 TPALPP 132
TP P
Sbjct: 1339 TPGGEP 1344
Score = 41.2 bits (95), Expect = 0.005
Identities = 43/235 (18%), Positives = 90/235 (38%), Gaps = 4/235 (1%)
Query: 183 VQAQAQAQAQAQAQAQAQAQAQAQAQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 241
V ++A+A + +++ ++ ++ +++ + ++ + + A+ + + + + + A+ +
Sbjct: 1103 VTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAG 1162
Query: 242 QVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTT 301
+ + A A GA + V T + P S + V P
Sbjct: 1163 PEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPP-LPVGVEEPAD 1221
Query: 302 QDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPV 361
+ P ++ + +P P A V+ P P+ P P+P +P
Sbjct: 1222 SREPPEEP-GLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQP 1280
Query: 362 MVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTE 416
+PP R P P P P P P + P + +P L G+ A S+ TE
Sbjct: 1281 PLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPG-LCGSLAKSQSTE 1334
Score = 39.3 bits (90), Expect = 0.020
Identities = 39/130 (30%), Positives = 49/130 (37%), Gaps = 33/130 (25%)
Query: 29 FRGPAPPPNAVMRGPPPLMRPP-------PPFGMMRGP---PPPPRP---------PFGR 69
F PAP P+ G P R P P F GP P P P P
Sbjct: 1365 FSYPAPSPSLSSGGLP---RTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLAS 1421
Query: 70 PPFDPNMPPMPPPGGIPPPMGPPHLQR---------PPFMPPPMSSMPPPPGMMFPPGMP 120
P P+P P +P P+ P + R PP +P P++S PPP M PG P
Sbjct: 1422 PVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPP--MKRKPGRP 1479
Query: 121 PVTAPGTPAL 130
+ P +L
Sbjct: 1480 RRSPPSMLSL 1489
Score = 38.5 bits (88), Expect = 0.035
Identities = 44/162 (27%), Positives = 49/162 (30%), Gaps = 51/162 (31%)
Query: 16 PGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP------------PPP 63
P L +A LR + AP P + P PL PPP G P P
Sbjct: 1436 PLPLPLALPAVLRAQARAPTPLPPLL-PAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLV 1494
Query: 64 RPPFGRP--------PFDPNMPPMPPP------------GGIPPPMGPPHLQRPPFMPPP 103
RPP G P P P P GIP P PPP
Sbjct: 1495 RPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAP------------PPP 1542
Query: 104 MSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDG 145
+ PPPP PP PP P + W P G
Sbjct: 1543 LPPQPPPP----PP--PPPVEPTKLPFKELDNQWPSEAIPPG 1578
Score = 37.0 bits (84), Expect = 0.10
Identities = 33/107 (30%), Positives = 39/107 (36%), Gaps = 34/107 (31%)
Query: 36 PNAVMRGPP-------PLMRPPPPFGMMRG----PPPPPRPPF----------------G 68
P R PP PL+RPP + R P P P F G
Sbjct: 1476 PGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAG 1535
Query: 69 RPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPP----PMSSMPPPP 111
P P +PP PPP PPP+ P L PF P ++PP P
Sbjct: 1536 IPAPPPPLPPQPPPPPPPPPVEPTKL---PFKELDNQWPSEAIPPGP 1579
Score = 36.2 bits (82), Expect = 0.17
Identities = 49/182 (26%), Positives = 68/182 (37%), Gaps = 26/182 (14%)
Query: 409 TAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMET 468
TA+SE +E D T+ K + E E E E S +
Sbjct: 1081 TALSEASEKDEGDSD----EEETVSIVTSKAEATSSSESSESSEFESSSESSP------S 1130
Query: 469 EEEDPKEEPIKEIKEEPKEEEMTEEEKAA--------QKAKPVATAPIPGTPWCVVWTGD 520
ED +E +E +EE +EEEM EE A Q + A A PG P +
Sbjct: 1131 SSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALA--PGAPAVDSLGME 1188
Query: 521 ERVFFYN----PTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGM-EELKKLRHPTPTMLS 575
E V P R SM D P +G + +EPP + G+ +E L P P
Sbjct: 1189 EEVDIETEAVAPEERPSMLDEPPLPVG-VEEPADSREPPEEPGLSQEGAMLLSPEPPAKE 1247
Query: 576 IQ 577
++
Sbjct: 1248 VE 1249
Score = 35.4 bits (80), Expect = 0.29
Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 20/109 (18%)
Query: 37 NAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPP-PMGPPHL- 94
NA + PPP + P PP PPPPP + PF + P IPP P G +
Sbjct: 1533 NAGIPAPPPPLPPQPP-----PPPPPPPVEPTKLPF-KELDNQWPSEAIPPGPRGRDEVT 1586
Query: 95 --------QRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEE 135
R P+ PP + PP P +P P P E
Sbjct: 1587 EEYMELAKSRGPWRRPPKKRHED----LVPPAGSPELSPPQPLFRPRSE 1631
Score = 33.5 bits (75), Expect = 1.1
Identities = 41/132 (31%), Positives = 53/132 (40%), Gaps = 18/132 (13%)
Query: 267 APAVSTSTSSSTPSSTTSTTTTATSVAQT--VSTPTTQDQTPSSAVSVATPTVSVSTPAP 324
+PAV T+ + +T + S+ +V T S P + Q SA TP + +TPAP
Sbjct: 333 SPAV-TAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAP 391
Query: 325 ----TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPA-----FPPVMVPPFRVPLPGMPI 375
+P QT P H PP P P T A A F PP P +
Sbjct: 392 GFKSAFSPYQT-PVAH---FPP--PPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAK 445
Query: 376 PLPGVLPGMAPP 387
PG PG PP
Sbjct: 446 EKPGTPPGPPPP 457
Score = 30.8 bits (68), Expect = 7.2
Identities = 56/247 (22%), Positives = 86/247 (34%), Gaps = 29/247 (11%)
Query: 265 SPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAP 324
+P+P++S+ TP S T T + + + P T P
Sbjct: 1369 APSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRD----------ERSGP 1418
Query: 325 TATPVQT-VPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPL---PGV 380
A+PV P P LP +P ++P A P + P PL P P+ PG
Sbjct: 1419 LASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPG- 1477
Query: 381 LPGMAPPIV-----PMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLEST 435
P +PP + P++ P A L T D +T + R
Sbjct: 1478 RPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIP 1537
Query: 436 WEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPK-EEEMTEEE 494
P L + P P EP + +E D + P + I P+ +E+TEE
Sbjct: 1538 APPP-------PLPPQPPPPPPPPPVEPTKLPFKELD-NQWPSEAIPPGPRGRDEVTEEY 1589
Query: 495 KAAQKAK 501
K++
Sbjct: 1590 MELAKSR 1596
Score = 30.4 bits (67), Expect = 9.4
Identities = 39/192 (20%), Positives = 82/192 (42%), Gaps = 6/192 (3%)
Query: 585 AIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPL-EARMK 643
++ EEQE EE E+E + ++ + DD+ D D E+ + E A E + ++ +
Sbjct: 1040 SLSEEQESTEE--EEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEE 1097
Query: 644 QFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNK 703
+ ++ + + S+ E + + ++ ++V + + EEE +
Sbjct: 1098 ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEES 1157
Query: 704 IMQA-KEDFKKMMEEAKFNPRA-TFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARK 761
+ A EDF++ EEA P A + D +A+ ++R ++ +E
Sbjct: 1158 MASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAP-EERPSMLDEPPLPVGV 1216
Query: 762 KEKEDSKTRGEK 773
+E DS+ E+
Sbjct: 1217 EEPADSREPPEE 1228
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 77.0 bits (188), Expect = 9e-14
Identities = 128/668 (19%), Positives = 273/668 (40%), Gaps = 153/668 (22%)
Query: 381 LPGMAPPIVPMIHPQVAIAASPATLAGATA---------VSEWTEYKTADGKTYYYNNRT 431
L G A ++ +H A A A + E T+ + A Y N T
Sbjct: 156 LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 215
Query: 432 LESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMT 491
E EK +L+EK +L E K I+ + +E K E K + P+++
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQ--------LNVKELKRKLERAKLLL--PQQQLQA 265
Query: 492 EEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKII 551
E + ++ + V+ +W+R +
Sbjct: 266 EADHLGKELQSVSAK------------------LQAQVEENELWNR------------LN 295
Query: 552 QEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDD 611
Q+ K +E K IQ+W+ I+E++E + E ++E ++ ++ K
Sbjct: 296 QQQEEKMWRQEEK-----------IQEWE---EKIQEQEEKIRE--QEEKIREQEEKMRR 339
Query: 612 NKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDP 671
+++ EKE M + + E+ E +M++ ++M+ WEKE
Sbjct: 340 QEEMMWEKEEKMRRQEEMMWEK-----EEKMRRQEEMM----------WEKE-------- 376
Query: 672 RYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAA 731
K R+Q EE EK+ KI + +E KM E+ K E
Sbjct: 377 ------EKMRRQ----------EEMMWEKEEKIRELEE---KMHEQEKIR------EQEE 411
Query: 732 KHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQS 791
K ++ + + EK +++E A +++E + + EKI+ + +
Sbjct: 412 KRQEEEKIREQEKRQEQE--------AKMWRQEEKIREQEEKIR------------EQEK 451
Query: 792 RWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKI--AKNLDSEKEKELERQARIEASLR 849
+ + ++K+ + + + +E++++Q EKI + + +KEK E++ +I
Sbjct: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQE-EKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
Query: 850 EREREVQKARSEQTKEIDREREQHKREEAIQNFKALL--SDMVRSSDVSWSDTRRTLRKD 907
+ R+ +K R ++ K ++E + ++EE I+ + + + + + W + +R ++D
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
Query: 908 HRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDP 967
W + RE++EK++ + + +++E RQ +E WK+ +KI +++
Sbjct: 571 KMWRQEEKI-REQEEKVWRQEEKI---REQEEKRQEQEE-------KMWKQEEKIREQEE 619
Query: 968 RCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVE 1027
+ +K RE EE IR++ + + ++ + + + +K+ ++ + + E
Sbjct: 620 KI----QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE 675
Query: 1028 KILQNDKR 1035
KI + +K+
Sbjct: 676 KIREQEKK 683
Score = 73.2 bits (178), Expect = 1e-12
Identities = 102/529 (19%), Positives = 232/529 (43%), Gaps = 90/529 (17%)
Query: 428 NNRTLESTW---EKPQELKEK-EKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKE 483
N + E W EK QE +EK ++ EEKI+E ++ E+ M +EE E KE K
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE---KEEKM 351
Query: 484 EPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIG 543
+EE M E+E+ ++ + + +W +E++ MW++ +
Sbjct: 352 RRQEEMMWEKEEKMRRQEEM------------MWEKEEKM----RRQEEMMWEKEEK--- 392
Query: 544 RADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVK 603
I+E K M E +K+R +K I+E+++ E+ E + +
Sbjct: 393 -------IRELEEK--MHEQEKIREQEEKRQEEEK-------IREQEKRQEQ--EAKMWR 434
Query: 604 AKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKE 663
+++ R+ + I +++ E K + I E R +Q ++M + E++
Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ-EEMWRQ---------EEK 484
Query: 664 LHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEER-REKKNKIMQAKEDFKKMMEEAKFNP 722
+H E+++++ Q K +EE+ R+++ K+ + +E ++ E+ +
Sbjct: 485 IH--------------EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530
Query: 723 RATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELL 782
+ + ++ ++ EKM ++E ++ E +++E+ED R E+ + E +
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEE----EKRQEQEDKMWRQEEKIREQEEKV 586
Query: 783 SNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKEL---- 838
+ + R + K + + + +K + +E+ ++ EKI + + +E+E
Sbjct: 587 WRQ--EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQE 644
Query: 839 --ERQARIEASLREREREVQKARSEQTKEIDREREQHKR----EEAIQNFKALLSDMVRS 892
E+ E + E+E ++Q+ ++ ++ REQ K+ EE I+ + ++ +
Sbjct: 645 QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ--- 701
Query: 893 SDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHI--EALTKKKREH 939
+ W + ++ + + R ++EK++ + + +K +EH
Sbjct: 702 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 77.0 bits (188), Expect = 9e-14
Identities = 94/400 (23%), Positives = 144/400 (36%), Gaps = 28/400 (7%)
Query: 26 ALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGI 85
A P P A +R P P P + P P P P + P P +
Sbjct: 978 ATTVHAPEEPDTAAVRVSTP-EEPASPAAAVPTPEEPTSPAAAVPTPEE---PTSPAAAV 1033
Query: 86 PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFP-PGMP--PVTAPGTPALPPTEEIWVENKT 142
PPP P P P P P P P P P A TP P + V T
Sbjct: 1034 PPPEEPTS----PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP--T 1087
Query: 143 PDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQ 202
P+ A T P + +P A + + A A + A
Sbjct: 1088 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPA 1147
Query: 203 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPT 262
++ + A A + A A A++ + A V A ++ + + AS PT
Sbjct: 1148 PAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLE---EPTSPAASVPT 1204
Query: 263 TSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVS---V 319
PA V+T ++P+++ T+ S+A VS P ++ ++ PT S V
Sbjct: 1205 ---PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAV 1261
Query: 320 STPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTT---AIPAFPPVMVPPFRVPLPGMP-I 375
TP ++P +VP P P A ++ +P + A+P +P VP P +P I
Sbjct: 1262 LTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAI 1321
Query: 376 PLPGVLP--GMAPPIVPMIHPQVAIAASPATLAGATAVSE 413
P V P ++P VP + + P + G + E
Sbjct: 1322 PAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEE 1361
Score = 58.5 bits (140), Expect = 3e-08
Identities = 71/295 (24%), Positives = 97/295 (32%), Gaps = 32/295 (10%)
Query: 233 AQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292
A A +A V A + + A A+ + APAV+ + + S+ + ++
Sbjct: 899 AAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAAL 958
Query: 293 AQTVSTPTTQDQTPSSAVSVATPT----------VSVSTPAPTATPVQTVPQPHPQTLPP 342
A TV T +D TP V+ AT V VSTP A+P VP P T P
Sbjct: 959 AITVPI-TEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPA 1017
Query: 343 AVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASP 402
A + +PT+ A PP P P +P P P A P A +P
Sbjct: 1018 AAVPTPEEPTSPAAAVPPPEEP--TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1075
Query: 403 ATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEE 462
A E T+ + P+E +EP +
Sbjct: 1076 EEPTSPAAAVPTPEEPTSPA-----------AAVPTPEEPTSPAAAVPTPEEPASPAAAV 1124
Query: 463 PLPMETEEE----DPKEEPIKEIKEEPKEEEMTEEEKAA----QKAKPVATAPIP 509
P P E EEP P EE A + A P A P P
Sbjct: 1125 PTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTP 1179
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 76.6 bits (187), Expect = 1e-13
Identities = 115/551 (20%), Positives = 232/551 (42%), Gaps = 75/551 (13%)
Query: 429 NRTLESTWEKPQELKEKEK-----------LEEKIKEPIKEPSEEPLPMETEEEDPKE-- 475
N E W + +EL+E+EK EE+++E + E+ M +E+ +E
Sbjct: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289
Query: 476 ----EPIKEIKEEPK----EEEMTE-EEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFY 526
E KE++E+ K EE+M E EEK ++ + + +W +ER++
Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK------MWRQEERLWEQ 343
Query: 527 NPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAI 586
R D + D+ ++E + M E +K+ M ++ + +
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEER--MREQEKMWEQEEKMQEEERIREREKKM 401
Query: 587 KEEQELMEEINE-----DEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEAR 641
+EE+E M E E +E + ++ K + + +KE E E +E I E +
Sbjct: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 642 MKQFKDMLLER---------GVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTR 692
++ ++M + WE+E + + D + + +ER +++Q + R
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQE--EKMRDQEQKMWDQEER--MWEQDERLR 517
Query: 693 AEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALF 752
+EER ++ K+ Q +E KM EE K T + ++ + + E+M++RE
Sbjct: 518 EKEERMREQKKMWQQEE---KMREEKK-----TQEQEKKTWDQEEKMREEERMREREKKM 569
Query: 753 NEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSS 812
E R++E E + + EK++ E + Q + K+ ++ E + D
Sbjct: 570 REEEEMMREQE-EKMQEQEEKMREQ-EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
Query: 813 SMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQ----KARSEQTKEIDR 868
+E++ + EK+ + + E+E E+ E +RE+E ++Q K R ++ K +
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQE-EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQ 686
Query: 869 EREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEH 928
E + ++EE ++ + M + W + ++ E EKE+ +
Sbjct: 687 EEKMREQEEKMRGQE---EKMWGQEEKMWGQEEKMWGQE---------EMREKEERIRDQ 734
Query: 929 IEALTKKKREH 939
E + ++ EH
Sbjct: 735 KEKMQERLPEH 745
Score = 76.3 bits (186), Expect = 1e-13
Identities = 114/631 (18%), Positives = 265/631 (41%), Gaps = 87/631 (13%)
Query: 411 VSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIK-EPSEEPLPMETE 469
+ E T+ + A Y N T E +K EL+EK +L E K I+ E +E
Sbjct: 161 IEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERA 220
Query: 470 EEDPKEEPIKEIKEE--PKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYN 527
+ + ++EE +EEE+ E+EK +K + +W +ER+
Sbjct: 221 KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEE------------KMWRQEERL---- 264
Query: 528 PTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIK 587
R + R +K+ ++ K+ E+ K+LR + +K + ++
Sbjct: 265 ---------REQEGKMREQEEKMRRQ--EKRLREQEKELREQEKELREQKKLREQEEQMQ 313
Query: 588 EEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKD 647
E++E M E E + +K R + + + EK+ + + +E + + R+++ ++
Sbjct: 314 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 373
Query: 648 MLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQA 707
+ E+ WE+E K+ + R + K++ ++ R +EE+ +K+ + M
Sbjct: 374 RMREQE----KMWEQE-EKMQEEERI----REREKKMREEEETMREQEEKMQKQEENMWE 424
Query: 708 KEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARK---KEK 764
+E+ + + + + + ++ ++ EK++D+E ++ + R+ +E+
Sbjct: 425 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
Query: 765 EDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIE 824
ED E+ D Q W + + E D R + + + Q E
Sbjct: 485 EDQMWEQEEKMRD----------QEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE 534
Query: 825 KIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKA 884
K+ +EK+ + Q + E+ RE ++ R + K + E ++EE +Q
Sbjct: 535 KM------REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE--- 585
Query: 885 LLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLL 944
+ + +++ WE ++ E++EK++ E E + +++ E Q
Sbjct: 586 -------------QEEKMREQEEKMWEQEEKMQ-EQEEKMW-EQEEKMWEQEEEDKMQEQ 630
Query: 945 DETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKE 1004
+E W++ +K+ +++ + + +K RE EE +R++ + + ++
Sbjct: 631 EE-------MMWEQEEKMQEQEEKMWE----QEEKMREQEEKMREQEEKMQGQEEKMREQ 679
Query: 1005 TKFITYRSKKLIQESDQHLKDVEKILQNDKR 1035
+ + + +K+ ++ ++ EK+ +++
Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Score = 68.9 bits (167), Expect = 2e-11
Identities = 90/454 (19%), Positives = 190/454 (41%), Gaps = 75/454 (16%)
Query: 650 LERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAK- 708
L+R +SA STW K+ RY+ KER + + + E +KKN +Q K
Sbjct: 143 LQRALSAVSTWHKKAD------RYIEELTKERDALSLELYRNTITNEELKKKNAELQEKL 196
Query: 709 --------------EDFKKMMEEAKF-----------------NPRATFSEFAAKHAKDS 737
++ K+ +E AKF E + ++
Sbjct: 197 RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 256
Query: 738 RFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVK 797
++ E+++++E E R++EK + + ++++ EL L Q + +
Sbjct: 257 MWRQEERLREQEGKMREQEEKMRRQEKR-LREQEKELREQEKELREQKKLREQEEQMQEQ 315
Query: 798 DKV--ESDPRYKAVDSSSMRED-----LFKQYIEKIAKNLDSEKE--KELERQARIEASL 848
++ E + + + + R++ KQ E+ K D E+ ++ ER E +
Sbjct: 316 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 375
Query: 849 REREREVQKARSEQTKEIDREREQHKREEAI------QNFKALLSDMVRSSDVSWSDTRR 902
RE+E+ ++ Q +E RERE+ REE + + +M + W R
Sbjct: 376 REQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 435
Query: 903 TLRKDHRWESGSLLEREEK-----------EKLFNEHIEALTKKK-REHFRQLLDETSAI 950
+K+ WE + E+EEK E+++ + + ++K RE Q+ ++ +
Sbjct: 436 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 495
Query: 951 --TLTSTWKEVKKIIKEDPRCIKFSS--SDRKKQREFEEYIRDKYITAKADFRT-----L 1001
W + +++ ++D R + ++KK + EE +R++ T + + +T
Sbjct: 496 RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK 555
Query: 1002 LKETKFITYRSKKLIQESDQHLKDVEKILQNDKR 1035
++E + + R KK+ +E + + EK+ + +++
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
Length = 780
Score = 76.6 bits (187), Expect = 1e-13
Identities = 116/491 (23%), Positives = 172/491 (35%), Gaps = 31/491 (6%)
Query: 22 AQQQALRFRGPAPPPNAVMRGPPPLMRPPPPF-GMMRGPPP-----PPRPPFGRPPFDPN 75
AQ Q+ P PPP V P PPF G GP P P P G P
Sbjct: 264 AQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQT 323
Query: 76 MPP----MPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPG-MPPVTAPGTPAL 130
+PP + P PP P + P P + P P PPG + PV G
Sbjct: 324 LPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP---QIPPGHLLPVQPSGQSEY 380
Query: 131 PPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQ 190
++ +P A + +A T P G S ++ A +Q ++A A
Sbjct: 381 LQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQ-PSEAMAP 439
Query: 191 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQ 250
AQ A Q A Q Q Q+ Q + A V
Sbjct: 440 RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSA-VPGG 498
Query: 251 VQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAV 310
A G + PAP+V S ST S T + +Q +S+ T ++ S
Sbjct: 499 PHAVVPGVPNVPAAVPAPSV---PSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQ 555
Query: 311 SVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPL 370
V P + APT+ P + Q QT P V Q P+ PP +
Sbjct: 556 HVGLPLAPGTHSAPTSLPQSDLSQFQTQTQP-----LVGQVDDTRRKSEPLPQPPLSLIA 610
Query: 371 PGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNN- 429
P+ P V +A P+ + P ++A S ++A E TA + ++ N
Sbjct: 611 ENKPVVKPPVADSLANPL--QLTPMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTL 668
Query: 430 RTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEE 489
+ +S W+ ++ KI++ + + EE + +E IKE+ E
Sbjct: 669 KESKSLWDSASG-GGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVE---RNS 724
Query: 490 MTEEEKAAQKA 500
+ E E A K+
Sbjct: 725 LLERENALLKS 735
Score = 49.3 bits (116), Expect = 2e-05
Identities = 61/272 (22%), Positives = 94/272 (34%), Gaps = 33/272 (12%)
Query: 173 LTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 232
++P L Q+ A A A A A++ + A A A A A A A +
Sbjct: 84 VSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLAGSS 143
Query: 233 AQAQAQAQAQVQAQVQAQVQAQAV--GASTP--------------------TTSSPAPAV 270
A A +Q ++ + + G+ P T S
Sbjct: 144 AGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIR 203
Query: 271 STSTSSSTPSSTTSTTTTATSVAQTVST------PTTQDQTPSSAVSVATPTVSVSTPAP 324
+ST T + T SV V++ P + + +AVS P+ +S P P
Sbjct: 204 HSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTP 263
Query: 325 TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPG- 383
+V QP P PP V +V Q + +P FP P + P G PG
Sbjct: 264 AQPQSFSVGQPQPP--PPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGG 321
Query: 384 --MAPPIVPMIHPQVAIAASPATLAGATAVSE 413
+ P V + P +++ P GA A +
Sbjct: 322 QTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQ 353
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/321 (23%), Positives = 114/321 (35%), Gaps = 46/321 (14%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPP---PPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
P PPP GPP + PP + PP PPP P PP P+M P PPP +
Sbjct: 140 PPPPPGPA-PGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPP--VLEA 196
Query: 89 MGPPHLQRPPFMPPPMSSMPPPPGMMF-PPGMPPVTAPGTPALPPTEEIWVENKTPDGKV 147
+ PPH P +P P +PP P + F P PPV AP PA + P G
Sbjct: 197 LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256
Query: 148 YY-----YNARTRESAWTKPDGVKVIQQSEL--------------------TPMLAAQAQ 182
+ N R E+ P + TP+ +
Sbjct: 257 KWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 183 VQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA---- 237
VQ AQ + + A +A ++ + +Q + + +A A A
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 238 -QAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTST--------SSSTPSSTTSTTTT 288
Q+Q+Q + A + P PAP + + ++ P+ T T +
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS 436
Query: 289 ATSVAQTVSTPTTQDQTPSSA 309
++ + P + + T SSA
Sbjct: 437 SSPALKPKPNPPSPENTASSA 457
Score = 50.4 bits (119), Expect = 9e-06
Identities = 85/366 (23%), Positives = 121/366 (33%), Gaps = 81/366 (22%)
Query: 59 PPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPG 118
PPPPP P G PP D + PPGG P P PP ++ PPPP ++ PP
Sbjct: 140 PPPPPGPAPG-PPQDIS----EPPGGSPLPS------------PPSTAPPPPPLLLEPP- 181
Query: 119 MPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLA 178
PP P++ P +E +P + + S T PD + P LA
Sbjct: 182 -PP------PSMAPPPPPVLEALSPP------HTLSSPSIPTPPDFIPP------APPLA 222
Query: 179 AQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 238
A A A + + A QA+A + ++ A+
Sbjct: 223 FLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAE 282
Query: 239 AQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVST 298
+ A+G + P P ++ S P T +T S
Sbjct: 283 PKGS------------ALGPN------PEPHLTFPRSFKVPPPTP---------VRTSSI 315
Query: 299 PTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLP-PAVPHSVPQPTTAIP- 356
P + Q AT P P + ++ Q +P P P P + A P
Sbjct: 316 PVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPR 375
Query: 357 -----------AFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPI---VPMIHPQVAIAASP 402
A P PP P P +P P P LP APP+ HP +P
Sbjct: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPAP-PLPPAAPPLPCAQKAAHPPAGFTKTP 434
Query: 403 ATLAGA 408
+ + A
Sbjct: 435 KSSSPA 440
Score = 48.9 bits (115), Expect = 3e-05
Identities = 48/184 (26%), Positives = 71/184 (38%), Gaps = 14/184 (7%)
Query: 315 PTVSVSTP---APTATPVQTVPQPHPQTL-PPAVPHSVPQPTTAIPAF-PPVMVPPFRVP 369
P +S P +P +P T P P P L PP P P P + A PP + +P
Sbjct: 150 PPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIP 209
Query: 370 LPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPAT----LAGATAVSEWTEYKTADGKTY 425
P IP L +APP P+ P ASP T L V++W +G+
Sbjct: 210 TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQA 269
Query: 426 YYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEP 485
+ + +P+ E + P P P+ T P++E +E P
Sbjct: 270 EATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT-----SSIPVQEAQEAP 324
Query: 486 KEEE 489
++EE
Sbjct: 325 RKEE 328
Score = 45.1 bits (105), Expect = 4e-04
Identities = 79/428 (18%), Positives = 133/428 (31%), Gaps = 45/428 (10%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPP------PPRPPFGRPPFDPNMPPMPP--- 81
GP P P+ P + PPP + P PR G P+ P+PP
Sbjct: 289 GPNPEPHLTF---PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFH 345
Query: 82 --------PGGIPPPMGPPHLQRPPFMPPPMSSMP---------PPPGMMFPPGMPPVTA 124
P P P P L+ P + PPP PP PP+
Sbjct: 346 IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP 405
Query: 125 PGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQ 184
P P P + K + S KP ++ A+ A V
Sbjct: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT-----ASSAPVD 460
Query: 185 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQ 244
+ +Q + A ++ + + + A + + + + +
Sbjct: 461 WRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA 520
Query: 245 AQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTP--SSTTSTTTTATSVAQTVSTPTTQ 302
V +++G S+ T + AP+++ + P S T S + +S+ +
Sbjct: 521 KDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEK 580
Query: 303 DQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVM 362
+ PS P + + +P + LPP +P + A
Sbjct: 581 EAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPA 640
Query: 363 VPPFRVPLPGM-------PIPLPGVLPGMAPPIVPMIHPQVAIAAS--PATLAGATAVSE 413
+PP P P + P P G A P+ P + A+ PA + AT +
Sbjct: 641 IPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPT 700
Query: 414 WTEYKTAD 421
T A+
Sbjct: 701 TTSQLMAE 708
Score = 41.6 bits (96), Expect = 0.004
Identities = 90/414 (21%), Positives = 134/414 (32%), Gaps = 75/414 (18%)
Query: 9 GESERFNPGELRMAQQQALRF-RGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPF 67
GE + P R+ Q Q+ R PPP + P P + PP PP PP
Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP-------APPLPP---- 412
Query: 68 GRPPFDPNMPPMPPPGGI--PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM------ 119
PP PP G P P L+ P P P ++ P P
Sbjct: 413 AAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRN 472
Query: 120 --------------------PPVTAPGT------PALPPTEEI--WVENKTPDG---KVY 148
P AP + P LP E + TP G K
Sbjct: 473 ELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSL 532
Query: 149 YYNARTRESA---WTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQA 205
++ T A T P V I Q TP + Q++ + +A+ + A+ +A+
Sbjct: 533 GGSSLTETEAAPSLTLP-SVDYIPQDSPTPSV---RQIRNELEARLSSAAEKEAKPSI-G 587
Query: 206 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSS 265
+ + + + A ++ A+ + Q +A +G + P ++
Sbjct: 588 SLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAM-LGPAIPPKAT 646
Query: 266 PAPAV------------STSTSSSTPSSTTSTTTT---ATSVAQTVSTPTTQDQTPSSAV 310
P PA+ + +TP TS TT ATS ST TT T S +
Sbjct: 647 PEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLM 706
Query: 311 SVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVP 364
+ + P + V T Q + P Q + AFPP P
Sbjct: 707 AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
Score = 37.7 bits (86), Expect = 0.059
Identities = 59/266 (22%), Positives = 87/266 (32%), Gaps = 32/266 (12%)
Query: 29 FRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
F PAPP + PPP+ P PP P P R + PPGG+
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPP------APASPHTVGTR---------LFPPGGVTKW 258
Query: 89 MGPPHLQ----RPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP-----TEEIWVE 139
L PP S P + P P +T P + +PP T I V+
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
Query: 140 NKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQA 199
+ + S P + S++ P A + + +A A A +
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL-- 376
Query: 200 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGAS 259
Q+Q+QA +A A A A + AQ A
Sbjct: 377 ---GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPC---AQKAAHPPAGF 430
Query: 260 TPTTSSPAPAVSTSTSSSTPSSTTST 285
T T S +PA+ + +P +T S+
Sbjct: 431 TKTPKSSSPALKPKPNPPSPENTASS 456
Score = 35.0 bits (79), Expect = 0.38
Identities = 51/264 (19%), Positives = 81/264 (30%), Gaps = 58/264 (21%)
Query: 100 MPPPMSSMPPP----PGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTR 155
+PP +++ P P M P +PP P PA+PP +W T
Sbjct: 618 LPPQSTTLLPTTSLQPKAMLGPAIPPKATP-EPAIPPKATLW--------------PATP 662
Query: 156 ESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 215
A P TP+ A A
Sbjct: 663 PKATLGPATPLKATSGPTTPLKATSGPAIAST---------------------------- 694
Query: 216 QAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTS 275
A +Q A+ + Q + A + +QA G +P+ ++ P +S
Sbjct: 695 ---ATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSS 751
Query: 276 SSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQP 335
++ P T+ + P + S V+V PT++ A PV+ P
Sbjct: 752 AAFPPKTSP----GGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807
Query: 336 HPQTLPPAVPHSVPQPTTAIPAFP 359
PA P + QPT + P
Sbjct: 808 G----LPAKPPASAQPTDELLRHP 827
Score = 30.8 bits (68), Expect = 7.2
Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 3/56 (5%)
Query: 340 LPPAVPHSVPQPTTAI---PAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMI 392
+PP P P P I P P+ PP P P + P P MAPP P++
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVL 194
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/321 (23%), Positives = 114/321 (35%), Gaps = 46/321 (14%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPP---PPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
P PPP GPP + PP + PP PPP P PP P+M P PPP +
Sbjct: 140 PPPPPGPA-PGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPP--VLEA 196
Query: 89 MGPPHLQRPPFMPPPMSSMPPPPGMMF-PPGMPPVTAPGTPALPPTEEIWVENKTPDGKV 147
+ PPH P +P P +PP P + F P PPV AP PA + P G
Sbjct: 197 LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256
Query: 148 YY-----YNARTRESAWTKPDGVKVIQQSEL--------------------TPMLAAQAQ 182
+ N R E+ P + TP+ +
Sbjct: 257 KWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 183 VQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA---- 237
VQ AQ + + A +A ++ + +Q + + +A A A
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 238 -QAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTST--------SSSTPSSTTSTTTT 288
Q+Q+Q + A + P PAP + + ++ P+ T T +
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS 436
Query: 289 ATSVAQTVSTPTTQDQTPSSA 309
++ + P + + T SSA
Sbjct: 437 SSPALKPKPNPPSPENTASSA 457
Score = 50.4 bits (119), Expect = 9e-06
Identities = 85/366 (23%), Positives = 121/366 (33%), Gaps = 81/366 (22%)
Query: 59 PPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPG 118
PPPPP P G PP D + PPGG P P PP ++ PPPP ++ PP
Sbjct: 140 PPPPPGPAPG-PPQDIS----EPPGGSPLPS------------PPSTAPPPPPLLLEPP- 181
Query: 119 MPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLA 178
PP P++ P +E +P + + S T PD + P LA
Sbjct: 182 -PP------PSMAPPPPPVLEALSPP------HTLSSPSIPTPPDFIPP------APPLA 222
Query: 179 AQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 238
A A A + + A QA+A + ++ A+
Sbjct: 223 FLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAE 282
Query: 239 AQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVST 298
+ A+G + P P ++ S P T +T S
Sbjct: 283 PKGS------------ALGPN------PEPHLTFPRSFKVPPPTP---------VRTSSI 315
Query: 299 PTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLP-PAVPHSVPQPTTAIP- 356
P + Q AT P P + ++ Q +P P P P + A P
Sbjct: 316 PVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPR 375
Query: 357 -----------AFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPI---VPMIHPQVAIAASP 402
A P PP P P +P P P LP APP+ HP +P
Sbjct: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPAP-PLPPAAPPLPCAQKAAHPPAGFTKTP 434
Query: 403 ATLAGA 408
+ + A
Sbjct: 435 KSSSPA 440
Score = 48.9 bits (115), Expect = 3e-05
Identities = 48/184 (26%), Positives = 71/184 (38%), Gaps = 14/184 (7%)
Query: 315 PTVSVSTP---APTATPVQTVPQPHPQTL-PPAVPHSVPQPTTAIPAF-PPVMVPPFRVP 369
P +S P +P +P T P P P L PP P P P + A PP + +P
Sbjct: 150 PPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIP 209
Query: 370 LPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPAT----LAGATAVSEWTEYKTADGKTY 425
P IP L +APP P+ P ASP T L V++W +G+
Sbjct: 210 TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQA 269
Query: 426 YYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEP 485
+ + +P+ E + P P P+ T P++E +E P
Sbjct: 270 EATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT-----SSIPVQEAQEAP 324
Query: 486 KEEE 489
++EE
Sbjct: 325 RKEE 328
Score = 45.1 bits (105), Expect = 4e-04
Identities = 79/428 (18%), Positives = 133/428 (31%), Gaps = 45/428 (10%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPP------PPRPPFGRPPFDPNMPPMPP--- 81
GP P P+ P + PPP + P PR G P+ P+PP
Sbjct: 289 GPNPEPHLTF---PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFH 345
Query: 82 --------PGGIPPPMGPPHLQRPPFMPPPMSSMP---------PPPGMMFPPGMPPVTA 124
P P P P L+ P + PPP PP PP+
Sbjct: 346 IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP 405
Query: 125 PGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQ 184
P P P + K + S KP ++ A+ A V
Sbjct: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT-----ASSAPVD 460
Query: 185 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQ 244
+ +Q + A ++ + + + A + + + + +
Sbjct: 461 WRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA 520
Query: 245 AQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTP--SSTTSTTTTATSVAQTVSTPTTQ 302
V +++G S+ T + AP+++ + P S T S + +S+ +
Sbjct: 521 KDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEK 580
Query: 303 DQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVM 362
+ PS P + + +P + LPP +P + A
Sbjct: 581 EAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPA 640
Query: 363 VPPFRVPLPGM-------PIPLPGVLPGMAPPIVPMIHPQVAIAAS--PATLAGATAVSE 413
+PP P P + P P G A P+ P + A+ PA + AT +
Sbjct: 641 IPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPT 700
Query: 414 WTEYKTAD 421
T A+
Sbjct: 701 TTSQLMAE 708
Score = 41.6 bits (96), Expect = 0.004
Identities = 90/414 (21%), Positives = 134/414 (32%), Gaps = 75/414 (18%)
Query: 9 GESERFNPGELRMAQQQALRF-RGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPF 67
GE + P R+ Q Q+ R PPP + P P + PP PP PP
Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP-------APPLPP---- 412
Query: 68 GRPPFDPNMPPMPPPGGI--PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM------ 119
PP PP G P P L+ P P P ++ P P
Sbjct: 413 AAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRN 472
Query: 120 --------------------PPVTAPGT------PALPPTEEI--WVENKTPDG---KVY 148
P AP + P LP E + TP G K
Sbjct: 473 ELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSL 532
Query: 149 YYNARTRESA---WTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQA 205
++ T A T P V I Q TP + Q++ + +A+ + A+ +A+
Sbjct: 533 GGSSLTETEAAPSLTLP-SVDYIPQDSPTPSV---RQIRNELEARLSSAAEKEAKPSI-G 587
Query: 206 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSS 265
+ + + + A ++ A+ + Q +A +G + P ++
Sbjct: 588 SLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAM-LGPAIPPKAT 646
Query: 266 PAPAV------------STSTSSSTPSSTTSTTTT---ATSVAQTVSTPTTQDQTPSSAV 310
P PA+ + +TP TS TT ATS ST TT T S +
Sbjct: 647 PEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLM 706
Query: 311 SVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVP 364
+ + P + V T Q + P Q + AFPP P
Sbjct: 707 AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
Score = 37.7 bits (86), Expect = 0.059
Identities = 59/266 (22%), Positives = 87/266 (32%), Gaps = 32/266 (12%)
Query: 29 FRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
F PAPP + PPP+ P PP P P R + PPGG+
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPP------APASPHTVGTR---------LFPPGGVTKW 258
Query: 89 MGPPHLQ----RPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP-----TEEIWVE 139
L PP S P + P P +T P + +PP T I V+
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
Query: 140 NKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQA 199
+ + S P + S++ P A + + +A A A +
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL-- 376
Query: 200 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGAS 259
Q+Q+QA +A A A A + AQ A
Sbjct: 377 ---GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPC---AQKAAHPPAGF 430
Query: 260 TPTTSSPAPAVSTSTSSSTPSSTTST 285
T T S +PA+ + +P +T S+
Sbjct: 431 TKTPKSSSPALKPKPNPPSPENTASS 456
Score = 35.0 bits (79), Expect = 0.38
Identities = 51/264 (19%), Positives = 81/264 (30%), Gaps = 58/264 (21%)
Query: 100 MPPPMSSMPPP----PGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTR 155
+PP +++ P P M P +PP P PA+PP +W T
Sbjct: 618 LPPQSTTLLPTTSLQPKAMLGPAIPPKATP-EPAIPPKATLW--------------PATP 662
Query: 156 ESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 215
A P TP+ A A
Sbjct: 663 PKATLGPATPLKATSGPTTPLKATSGPAIAST---------------------------- 694
Query: 216 QAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTS 275
A +Q A+ + Q + A + +QA G +P+ ++ P +S
Sbjct: 695 ---ATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSS 751
Query: 276 SSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQP 335
++ P T+ + P + S V+V PT++ A PV+ P
Sbjct: 752 AAFPPKTSP----GGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807
Query: 336 HPQTLPPAVPHSVPQPTTAIPAFP 359
PA P + QPT + P
Sbjct: 808 G----LPAKPPASAQPTDELLRHP 827
Score = 30.8 bits (68), Expect = 7.2
Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 3/56 (5%)
Query: 340 LPPAVPHSVPQPTTAI---PAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMI 392
+PP P P P I P P+ PP P P + P P MAPP P++
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVL 194
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/321 (23%), Positives = 114/321 (35%), Gaps = 46/321 (14%)
Query: 32 PAPPPNAVMRGPPPLMRPPPPFGMMRGPP---PPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
P PPP GPP + PP + PP PPP P PP P+M P PPP +
Sbjct: 140 PPPPPGPA-PGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPP--VLEA 196
Query: 89 MGPPHLQRPPFMPPPMSSMPPPPGMMF-PPGMPPVTAPGTPALPPTEEIWVENKTPDGKV 147
+ PPH P +P P +PP P + F P PPV AP PA + P G
Sbjct: 197 LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256
Query: 148 YY-----YNARTRESAWTKPDGVKVIQQSEL--------------------TPMLAAQAQ 182
+ N R E+ P + TP+ +
Sbjct: 257 KWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP 316
Query: 183 VQ-AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA---- 237
VQ AQ + + A +A ++ + +Q + + +A A A
Sbjct: 317 VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 238 -QAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTST--------SSSTPSSTTSTTTT 288
Q+Q+Q + A + P PAP + + ++ P+ T T +
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS 436
Query: 289 ATSVAQTVSTPTTQDQTPSSA 309
++ + P + + T SSA
Sbjct: 437 SSPALKPKPNPPSPENTASSA 457
Score = 50.4 bits (119), Expect = 9e-06
Identities = 85/366 (23%), Positives = 121/366 (33%), Gaps = 81/366 (22%)
Query: 59 PPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPG 118
PPPPP P G PP D + PPGG P P PP ++ PPPP ++ PP
Sbjct: 140 PPPPPGPAPG-PPQDIS----EPPGGSPLPS------------PPSTAPPPPPLLLEPP- 181
Query: 119 MPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLA 178
PP P++ P +E +P + + S T PD + P LA
Sbjct: 182 -PP------PSMAPPPPPVLEALSPP------HTLSSPSIPTPPDFIPP------APPLA 222
Query: 179 AQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 238
A A A + + A QA+A + ++ A+
Sbjct: 223 FLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAE 282
Query: 239 AQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVST 298
+ A+G + P P ++ S P T +T S
Sbjct: 283 PKGS------------ALGPN------PEPHLTFPRSFKVPPPTP---------VRTSSI 315
Query: 299 PTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLP-PAVPHSVPQPTTAIP- 356
P + Q AT P P + ++ Q +P P P P + A P
Sbjct: 316 PVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPR 375
Query: 357 -----------AFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPI---VPMIHPQVAIAASP 402
A P PP P P +P P P LP APP+ HP +P
Sbjct: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPAP-PLPPAAPPLPCAQKAAHPPAGFTKTP 434
Query: 403 ATLAGA 408
+ + A
Sbjct: 435 KSSSPA 440
Score = 48.9 bits (115), Expect = 3e-05
Identities = 48/184 (26%), Positives = 71/184 (38%), Gaps = 14/184 (7%)
Query: 315 PTVSVSTP---APTATPVQTVPQPHPQTL-PPAVPHSVPQPTTAIPAF-PPVMVPPFRVP 369
P +S P +P +P T P P P L PP P P P + A PP + +P
Sbjct: 150 PPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIP 209
Query: 370 LPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPAT----LAGATAVSEWTEYKTADGKTY 425
P IP L +APP P+ P ASP T L V++W +G+
Sbjct: 210 TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQA 269
Query: 426 YYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEP 485
+ + +P+ E + P P P+ T P++E +E P
Sbjct: 270 EATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT-----SSIPVQEAQEAP 324
Query: 486 KEEE 489
++EE
Sbjct: 325 RKEE 328
Score = 45.1 bits (105), Expect = 4e-04
Identities = 79/428 (18%), Positives = 133/428 (31%), Gaps = 45/428 (10%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPP------PPRPPFGRPPFDPNMPPMPP--- 81
GP P P+ P + PPP + P PR G P+ P+PP
Sbjct: 289 GPNPEPHLTF---PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFH 345
Query: 82 --------PGGIPPPMGPPHLQRPPFMPPPMSSMP---------PPPGMMFPPGMPPVTA 124
P P P P L+ P + PPP PP PP+
Sbjct: 346 IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP 405
Query: 125 PGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQ 184
P P P + K + S KP ++ A+ A V
Sbjct: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT-----ASSAPVD 460
Query: 185 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQ 244
+ +Q + A ++ + + + A + + + + +
Sbjct: 461 WRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA 520
Query: 245 AQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTP--SSTTSTTTTATSVAQTVSTPTTQ 302
V +++G S+ T + AP+++ + P S T S + +S+ +
Sbjct: 521 KDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEK 580
Query: 303 DQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVM 362
+ PS P + + +P + LPP +P + A
Sbjct: 581 EAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPA 640
Query: 363 VPPFRVPLPGM-------PIPLPGVLPGMAPPIVPMIHPQVAIAAS--PATLAGATAVSE 413
+PP P P + P P G A P+ P + A+ PA + AT +
Sbjct: 641 IPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPT 700
Query: 414 WTEYKTAD 421
T A+
Sbjct: 701 TTSQLMAE 708
Score = 41.6 bits (96), Expect = 0.004
Identities = 90/414 (21%), Positives = 134/414 (32%), Gaps = 75/414 (18%)
Query: 9 GESERFNPGELRMAQQQALRF-RGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPF 67
GE + P R+ Q Q+ R PPP + P P + PP PP PP
Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP-------APPLPP---- 412
Query: 68 GRPPFDPNMPPMPPPGGI--PPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM------ 119
PP PP G P P L+ P P P ++ P P
Sbjct: 413 AAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRN 472
Query: 120 --------------------PPVTAPGT------PALPPTEEI--WVENKTPDG---KVY 148
P AP + P LP E + TP G K
Sbjct: 473 ELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSL 532
Query: 149 YYNARTRESA---WTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQA 205
++ T A T P V I Q TP + Q++ + +A+ + A+ +A+
Sbjct: 533 GGSSLTETEAAPSLTLP-SVDYIPQDSPTPSV---RQIRNELEARLSSAAEKEAKPSI-G 587
Query: 206 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSS 265
+ + + + A ++ A+ + Q +A +G + P ++
Sbjct: 588 SLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAM-LGPAIPPKAT 646
Query: 266 PAPAV------------STSTSSSTPSSTTSTTTT---ATSVAQTVSTPTTQDQTPSSAV 310
P PA+ + +TP TS TT ATS ST TT T S +
Sbjct: 647 PEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLM 706
Query: 311 SVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVP 364
+ + P + V T Q + P Q + AFPP P
Sbjct: 707 AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
Score = 37.7 bits (86), Expect = 0.059
Identities = 59/266 (22%), Positives = 87/266 (32%), Gaps = 32/266 (12%)
Query: 29 FRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
F PAPP + PPP+ P PP P P R + PPGG+
Sbjct: 214 FIPPAPPLAFLAPPPPPVPAPAPP------APASPHTVGTR---------LFPPGGVTKW 258
Query: 89 MGPPHLQ----RPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP-----TEEIWVE 139
L PP S P + P P +T P + +PP T I V+
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
Query: 140 NKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQA 199
+ + S P + S++ P A + + +A A A +
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL-- 376
Query: 200 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGAS 259
Q+Q+QA +A A A A + AQ A
Sbjct: 377 ---GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPC---AQKAAHPPAGF 430
Query: 260 TPTTSSPAPAVSTSTSSSTPSSTTST 285
T T S +PA+ + +P +T S+
Sbjct: 431 TKTPKSSSPALKPKPNPPSPENTASS 456
Score = 35.0 bits (79), Expect = 0.38
Identities = 51/264 (19%), Positives = 81/264 (30%), Gaps = 58/264 (21%)
Query: 100 MPPPMSSMPPP----PGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTR 155
+PP +++ P P M P +PP P PA+PP +W T
Sbjct: 618 LPPQSTTLLPTTSLQPKAMLGPAIPPKATP-EPAIPPKATLW--------------PATP 662
Query: 156 ESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 215
A P TP+ A A
Sbjct: 663 PKATLGPATPLKATSGPTTPLKATSGPAIAST---------------------------- 694
Query: 216 QAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTS 275
A +Q A+ + Q + A + +QA G +P+ ++ P +S
Sbjct: 695 ---ATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSS 751
Query: 276 SSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQP 335
++ P T+ + P + S V+V PT++ A PV+ P
Sbjct: 752 AAFPPKTSP----GGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPP 807
Query: 336 HPQTLPPAVPHSVPQPTTAIPAFP 359
PA P + QPT + P
Sbjct: 808 G----LPAKPPASAQPTDELLRHP 827
Score = 30.8 bits (68), Expect = 7.2
Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 3/56 (5%)
Query: 340 LPPAVPHSVPQPTTAI---PAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMI 392
+PP P P P I P P+ PP P P + P P MAPP P++
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVL 194
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 75.1 bits (183), Expect = 3e-13
Identities = 54/132 (40%), Positives = 61/132 (46%), Gaps = 30/132 (22%)
Query: 22 AQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNM----- 76
A + LR + P PPP + RG PP PPPP GPPPPP G PP P+
Sbjct: 267 AVKNELRRQAPPPPPPS--RGGPP---PPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAA 321
Query: 77 PPMPPP----GGIPPPMGPPHLQRPPFMPPPM------SSMPPPP------GMMFPPGMP 120
PP PPP +PPP PP+ PP PPP S PPPP G + PP P
Sbjct: 322 PPPPPPSRPSVAVPPP--PPNRMYPP--PPPALPSSAPSGPPPPPPSVLGVGPVAPPPPP 377
Query: 121 PVTAPGTPALPP 132
P P P PP
Sbjct: 378 PPPPPPGPPPPP 389
Score = 67.8 bits (164), Expect = 5e-11
Identities = 49/113 (43%), Positives = 52/113 (46%), Gaps = 18/113 (15%)
Query: 31 GPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPP--RPPFGRPPFDPNM--PPMPP----- 81
GP PPP A RG PP PPP PPPPP RP PP PN PP PP
Sbjct: 298 GPPPPP-ARGRGAPP---PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSS 353
Query: 82 -PGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPT 133
P G PPP P L P PPP PPPP PP P + + G +P T
Sbjct: 354 APSG-PPPPPPSVLGVGPVAPPPP---PPPPPPPGPPPPPGLPSDGDHQVPTT 402
Score = 63.9 bits (154), Expect = 8e-10
Identities = 43/112 (38%), Positives = 48/112 (42%), Gaps = 13/112 (11%)
Query: 37 NAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQR 96
N + R PP PPPP PPPPP G PP PP G PPP
Sbjct: 270 NELRRQAPP---PPPPSRGGPPPPPPPPHNSGPPP-----PPARGRGAPPPPPSRAPTAA 321
Query: 97 PPFMPPPMSSM---PPPPGMMFPPGMP--PVTAPGTPALPPTEEIWVENKTP 143
PP PP S+ PPPP M+PP P P +AP P PP + V P
Sbjct: 322 PPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP 373
Score = 40.4 bits (93), Expect = 0.009
Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 12/88 (13%)
Query: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP---VM 362
PS A + A P P P + P VP P P + P P ++P + P PP +
Sbjct: 314 PSRAPTAAPP------PPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLG 367
Query: 363 VPPFRVPLPGMPIPLPGVLPGMAPPIVP 390
V P P P P P PG P PP +P
Sbjct: 368 VGPVAPPPPPPPPPPPGPPP---PPGLP 392
Score = 38.5 bits (88), Expect = 0.035
Identities = 34/131 (25%), Positives = 44/131 (33%), Gaps = 9/131 (6%)
Query: 247 VQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTT---STTTTATSVAQTVSTPTTQD 303
V+ +++ QA P+ P P +S P S A T + P
Sbjct: 268 VKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPP 327
Query: 304 QTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMV 363
PS AV P P P +P P PP P + A P PP
Sbjct: 328 SRPSVAVPPPPPNRMYPPPPP------ALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPP 381
Query: 364 PPFRVPLPGMP 374
PP P PG+P
Sbjct: 382 PPGPPPPPGLP 392
Score = 35.8 bits (81), Expect = 0.22
Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 9/79 (11%)
Query: 320 STPAPTATPVQTVPQPHPQTLPPAVPHSVP--QPTTAIPAFPP-VMVPPFRVPLP----- 371
S P P + P P P P A P P +P+ A+P PP M PP LP
Sbjct: 297 SGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPS 356
Query: 372 GMPIPLPGVLPGMAPPIVP 390
G P P P VL G+ P P
Sbjct: 357 GPPPPPPSVL-GVGPVAPP 374
Score = 35.0 bits (79), Expect = 0.38
Identities = 19/50 (38%), Positives = 20/50 (40%)
Query: 83 GGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPP 132
GG+ Q PP PP PPPP G PP A G A PP
Sbjct: 263 GGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPP 312
Score = 34.3 bits (77), Expect = 0.65
Identities = 29/81 (35%), Positives = 31/81 (38%), Gaps = 9/81 (11%)
Query: 322 PAPTATPVQTVPQPHP---QTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP---GMPI 375
P P P + P P P + PP P P TA P PP P VP P M
Sbjct: 288 PPPPPPPHNSGPPPPPARGRGAPPPPPSRAP---TAAPPPPPPSRPSVAVPPPPPNRMYP 344
Query: 376 PLPGVLPGMAPPIVPMIHPQV 396
P P LP AP P P V
Sbjct: 345 PPPPALPSSAPSGPPPPPPSV 365
Score = 31.2 bits (69), Expect = 5.5
Identities = 27/73 (36%), Positives = 29/73 (39%), Gaps = 9/73 (12%)
Query: 330 QTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIV 389
Q P P P P P P P + P PP PP R G P P P P APP
Sbjct: 275 QAPPPPPPSRGGPPPPP--PPPHNSGP--PP---PPARGR--GAPPPPPSRAPTAAPPPP 325
Query: 390 PMIHPQVAIAASP 402
P P VA+ P
Sbjct: 326 PPSRPSVAVPPPP 338
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 74.7 bits (182), Expect = 4e-13
Identities = 100/396 (25%), Positives = 137/396 (34%), Gaps = 59/396 (14%)
Query: 32 PAPPPNAVMR--GPPPLMR-----PPPPFGMMRGPPP--PPR---PPFGRPPFDPNMPPM 79
PA PP+ G P L P PP + PPP PP PP PP P PP+
Sbjct: 358 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 417
Query: 80 PPPGGIPPPMGPP----HLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEE 135
P P P P HL + PF PPP PP PP PPV+ TP
Sbjct: 418 SPLA-TPSPQAPNALAVHLLQAPFSPPP---SPPVQAPFSPPASPPVSPSATPP------ 467
Query: 136 IWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQA 195
++ S P ++V +P ++ A QA A
Sbjct: 468 ----------------SQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509
Query: 196 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQA 255
A+ QA A A QA A QA A QA A
Sbjct: 510 LQLAKPPPQA-PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
Query: 256 VGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATP 315
P + +P + TP TS + ++A P ++PSS +S P
Sbjct: 569 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS--GP 626
Query: 316 TVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVM-----VPP--FRV 368
++ + + T+TP + + P + P P + A P PP FR
Sbjct: 627 DLAGHSSSATSTPEELRGY---DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR- 682
Query: 369 PLPGMPIPLPGVL-PGMAPPIVPMIHPQVAIAASPA 403
PG P+P P PG A + + + +A+PA
Sbjct: 683 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 718
Score = 58.5 bits (140), Expect = 3e-08
Identities = 115/539 (21%), Positives = 170/539 (31%), Gaps = 101/539 (18%)
Query: 33 APPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPF--------DPNMPPMPPPGG 84
A P + PP RPPPP GR P +P P G
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 85 IPPPMGPPHLQRPPFMPPPMSS----MPP----PPGMMFPPGMPPVTAPGTPALPPTEEI 136
P R P PP S PP PG + PG T P I
Sbjct: 79 --PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 137 WVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQ 196
E GK R+ SA + D S TP + A + A +
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRD------TSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 197 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV 256
A + A+ + + ++ + A + + A+ + A +Q + + A
Sbjct: 191 RPAPS---ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 257 GASTPTTSSPA------------------------PAVSTSTSSSTPS----STTSTTTT 288
S+P S P+ P V+ + P+ S++ T
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 289 ATSVAQTVSTPTTQDQTPSSA---VSVATPTVSVSTPAPTATP-VQTVPQPHPQTLPPAV 344
+ S A P T TP S+ +ATP + ++ P+P+A P +QT+P P P T P
Sbjct: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATP-LPLAPPSPSAPPSLQTLPSP-PATPPSQA 365
Query: 345 PHSVPQPTTAI-------PAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVA 397
S+ PT P P+ PP + P P + +P P APP P P
Sbjct: 366 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAP-PALALP-----PLQAPPSPPASPPLSP 419
Query: 398 IAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIK 457
+A A AV L++ + P + P+
Sbjct: 420 LATPSPQAPNALAV------------------HLLQAPFSPPPSPPVQAPFSPPASPPVS 461
Query: 458 ----EPSEEP-----LPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAP 507
PS+ P P++ P P+ P + Q AKP AP
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 520
Score = 58.5 bits (140), Expect = 3e-08
Identities = 90/390 (23%), Positives = 119/390 (30%), Gaps = 56/390 (14%)
Query: 43 PPPLMRPPPPFGMMR--------------GPPPPPRPPFG---RPPFDPNMPPMPPPGGI 85
P P RP PP R P RP G + P ++ P
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251
Query: 86 PPPMGPPHLQRPPFMPPPMSSMPPPPGM--MFPPGMPPVTAPGTPALPPTEEIWVENKTP 143
P GP P P S P P G+ + PP + P PAL P + +P
Sbjct: 252 PARSGPSARGTP--RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
Query: 144 DGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQA 203
+ QS+ P L A + A A A
Sbjct: 310 SAAL----------------------QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347
Query: 204 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTT 263
Q A +QA + QA + QA A P
Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPT-LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 406
Query: 264 SSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVS-TP 322
+ P+P S S S + A + Q +P + A+P VS S TP
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466
Query: 323 APTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLP 382
A P P P +PP+ P S P +A P PP PP P + P P P
Sbjct: 467 PSQAPPSLAAP---PLQVPPSPPASPPMSPSATP--PPQAPPPLAAPPLQLAKPPPQAPP 521
Query: 383 GMAPPIVPMIHPQVAIAASPATLAGATAVS 412
+A P P A+ + PA+ G S
Sbjct: 522 ALATP------PLQALPSPPASFPGQAPFS 545
Score = 57.4 bits (137), Expect = 7e-08
Identities = 93/380 (24%), Positives = 126/380 (33%), Gaps = 68/380 (17%)
Query: 50 PPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPP-PGGIPPPMGPPHLQRPPFMP--PPMSS 106
P P G+ PP PP R P + P+ P P P Q PP +P P SS
Sbjct: 272 PKPKGLQALRPPQVTPP--RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
Query: 107 MP---------PPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRES 157
+ PP PP + T P PA PP++ A T
Sbjct: 330 LTCQLATPLPLAPPSPSAPPSLQ--TLPSPPATPPSQ-----------------ATTSLG 370
Query: 158 AWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 217
+ T + L+P+ Q A A QA A A QA
Sbjct: 371 SPTLQATHSFLPSPPLSPLATPPPQAPP-ALALPPLQAPPSPPASPPLSPLATPSPQAP- 428
Query: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277
A A QA QA A A + P+ ++P V S +S
Sbjct: 429 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488
Query: 278 TPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATP------VQT 331
P S ++T P + +A P + ++ P P A P +Q
Sbjct: 489 PPMSPSATPP------------------PQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 530
Query: 332 VPQPHPQTLPPAVPHS----VPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGM-AP 386
+P P P + P P S +P A P PP P PL +P P P P + AP
Sbjct: 531 LPSP-PASFPGQAPFSPSASLPMSPLATP--PPQAPPVLAAPLLQVP-PSPPASPTLQAP 586
Query: 387 PIVPMIHPQVAIAASPATLA 406
P P +++ TLA
Sbjct: 587 RRPPTPGPDTSVSGPRLTLA 606
Score = 34.3 bits (77), Expect = 0.65
Identities = 30/120 (25%), Positives = 44/120 (36%), Gaps = 15/120 (12%)
Query: 29 FRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPP 88
F A P + + PPP P +++ PP PP P + P PP P
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA---PRRPPTP-------- 592
Query: 89 MGPPHLQRPPFMPPPMSSMPPPPGMMFPPGM---PPVTAPGTPALPPTEEIWVENKTPDG 145
GP P + ++ PPPP P P + + A EE+ + P+G
Sbjct: 593 -GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,584,697
Number of Sequences: 37866
Number of extensions: 3777800
Number of successful extensions: 107913
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1310
Number of HSP's successfully gapped in prelim test: 2466
Number of HSP's that attempted gapping in prelim test: 25635
Number of HSP's gapped (non-prelim): 35687
length of query: 1077
length of database: 18,247,518
effective HSP length: 113
effective length of query: 964
effective length of database: 13,968,660
effective search space: 13465788240
effective search space used: 13465788240
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.