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Search of human proteins with 89886466
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89886466 hematopoietic signal peptide-containing isoform 1
[Homo sapiens]
(254 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89886466 hematopoietic signal peptide-containing isoform 1 [H... 505 e-143
gi|45580696 hematopoietic signal peptide-containing isoform 2 [H... 453 e-128
gi|17921982 heme A:farnesyltransferase [Homo sapiens] 37 0.013
gi|239755004 PREDICTED: hypothetical protein [Homo sapiens] 30 2.0
gi|4757886 pituitary tumor-transforming gene 1 protein-interacti... 30 2.0
gi|169790811 SHC (Src homology 2 domain containing) transforming... 30 2.7
gi|239742130 PREDICTED: hypothetical protein XP_002342439 [Homo ... 29 3.5
gi|223972612 Crm, cramped-like [Homo sapiens] 29 4.5
gi|239755267 PREDICTED: hypothetical protein [Homo sapiens] 29 4.5
gi|239749560 PREDICTED: hypothetical protein XP_002347086 [Homo ... 29 4.5
gi|239743710 PREDICTED: hypothetical protein XP_002342931 [Homo ... 29 4.5
gi|214010185 amyloid beta (A4) precursor-like protein 2 isoform ... 29 4.5
gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform ... 29 4.5
gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ... 29 4.5
gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ... 29 4.5
gi|24308458 Lix1 homolog (mouse) like [Homo sapiens] 28 5.9
gi|8922567 hypothetical protein LOC55194 [Homo sapiens] 28 5.9
gi|5032099 smoothened [Homo sapiens] 28 7.7
gi|126090909 engrailed homeobox 1 [Homo sapiens] 28 7.7
gi|19924103 synapsin II isoform IIa [Homo sapiens] 28 7.7
gi|114145479 neuroepithelial cell transforming gene 1 isoform 1 ... 28 7.7
gi|19924101 synapsin II isoform IIb [Homo sapiens] 28 7.7
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho... 28 7.7
>gi|89886466 hematopoietic signal peptide-containing isoform 1 [Homo
sapiens]
Length = 254
Score = 505 bits (1300), Expect = e-143
Identities = 254/254 (100%), Positives = 254/254 (100%)
Query: 1 MAAASAGATRLLLLLLMAVAAPSRARGSGCRAGTGARGAGAEGREGEACGTVGLLLEHSF 60
MAAASAGATRLLLLLLMAVAAPSRARGSGCRAGTGARGAGAEGREGEACGTVGLLLEHSF
Sbjct: 1 MAAASAGATRLLLLLLMAVAAPSRARGSGCRAGTGARGAGAEGREGEACGTVGLLLEHSF 60
Query: 61 EIDDSANFRKRGSLLWNQQDGTLSLSQRQLSEEERGRLRDVAALNGLYRVRIPRRPGALD 120
EIDDSANFRKRGSLLWNQQDGTLSLSQRQLSEEERGRLRDVAALNGLYRVRIPRRPGALD
Sbjct: 61 EIDDSANFRKRGSLLWNQQDGTLSLSQRQLSEEERGRLRDVAALNGLYRVRIPRRPGALD 120
Query: 121 GLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLEL 180
GLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLEL
Sbjct: 121 GLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLEL 180
Query: 181 FNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWHIILGGAVLLTAL 240
FNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWHIILGGAVLLTAL
Sbjct: 181 FNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWHIILGGAVLLTAL 240
Query: 241 RPAAPGPAPPPQEA 254
RPAAPGPAPPPQEA
Sbjct: 241 RPAAPGPAPPPQEA 254
>gi|45580696 hematopoietic signal peptide-containing isoform 2 [Homo
sapiens]
Length = 262
Score = 453 bits (1166), Expect = e-128
Identities = 232/245 (94%), Positives = 235/245 (95%), Gaps = 2/245 (0%)
Query: 1 MAAASAGATRLLLLLLMAVAAPSRARGSGCRAGTGARGAGAEGREGEACGTVGLLLEHSF 60
MAAASAGATRLLLLLLMAVAAPSRARGSGCRAGTGARGAGAEGREGEACGTVGLLLEHSF
Sbjct: 1 MAAASAGATRLLLLLLMAVAAPSRARGSGCRAGTGARGAGAEGREGEACGTVGLLLEHSF 60
Query: 61 EIDDSANFRKRGSLLWNQQDGTLSLSQRQLSEEERGRLRDVAALNGLYRVRIPRRPGALD 120
EIDDSANFRKRGSLLWNQQDGTLSLSQRQLSEEERGRLRDVAALNGLYRVRIPRRPGALD
Sbjct: 61 EIDDSANFRKRGSLLWNQQDGTLSLSQRQLSEEERGRLRDVAALNGLYRVRIPRRPGALD 120
Query: 121 GLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLEL 180
GLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLEL
Sbjct: 121 GLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLEL 180
Query: 181 FNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWHIILGGAVLLTAL 240
FNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYW I+ V+L +
Sbjct: 181 FNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWMYII--PVVLFLM 238
Query: 241 RPAAP 245
AP
Sbjct: 239 MSGAP 243
>gi|17921982 heme A:farnesyltransferase [Homo sapiens]
Length = 443
Score = 37.4 bits (85), Expect = 0.013
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 162 VTHPGGCRGHEVED-VDLELFNTSVQLQPPTTAPGPETA----AFIERLEMEQAQKAKNP 216
VTHPG CR + + L + + + + TT P A A+I L A
Sbjct: 347 VTHPGLCRRVALRHCLALLVLSAAAPVLDITTWTFPIMALPINAYISYLGFRFYVDADRR 406
Query: 217 QEQKSFFAKYWHIILGGAVLLTALRPAAPGPAPPP 251
++ FF WH+ L ++LT RP+ G A PP
Sbjct: 407 SSRRLFFCSLWHLPLLLLLMLTCKRPSGGGDAGPP 441
>gi|239755004 PREDICTED: hypothetical protein [Homo sapiens]
Length = 558
Score = 30.0 bits (66), Expect = 2.0
Identities = 33/106 (31%), Positives = 45/106 (42%), Gaps = 14/106 (13%)
Query: 2 AAASAGATRLLLLLLMAVA-------APSRARGSGCRAGTGARGAGAEGREGEACGTVGL 54
A ASAG+ R L + A RG G RAG G RGA E G A +
Sbjct: 61 ALASAGSRRCAPAALCSSGGCALTRRAACGGRGGGTRAGQGGRGAWGEAPVGSAALSSPT 120
Query: 55 LLEHSFEIDDSANFRKRGSLLWNQQDGTLSL-SQRQLSEEERGRLR 99
+ H S+ R +G+L G L L +QR+ ++ G +R
Sbjct: 121 GVSHLL----SSQLRGQGAL--ESCGGILPLAAQRRSMDKASGYVR 160
Score = 28.1 bits (61), Expect = 7.7
Identities = 16/26 (61%), Positives = 16/26 (61%), Gaps = 1/26 (3%)
Query: 24 RARGSGCRAGTGAR-GAGAEGREGEA 48
R RG G RAGTG R G GA G G A
Sbjct: 322 RQRGGGVRAGTGPRSGDGAFGTLGSA 347
>gi|4757886 pituitary tumor-transforming gene 1 protein-interacting
protein precursor [Homo sapiens]
Length = 180
Score = 30.0 bits (66), Expect = 2.0
Identities = 13/25 (52%), Positives = 14/25 (56%)
Query: 226 YWHIILGGAVLLTALRPAAPGPAPP 250
YW + LGGA LL L P A PP
Sbjct: 12 YWRLRLGGAALLLLLIPVAAAQEPP 36
>gi|169790811 SHC (Src homology 2 domain containing) transforming
protein 2 [Homo sapiens]
Length = 582
Score = 29.6 bits (65), Expect = 2.7
Identities = 17/43 (39%), Positives = 20/43 (46%)
Query: 1 MAAASAGATRLLLLLLMAVAAPSRARGSGCRAGTGARGAGAEG 43
+AAA GA + A SR RG+G R G RGA G
Sbjct: 75 LAAAVLGACEPRCAAPCPLPALSRCRGAGSRGSRGGRGAAGSG 117
>gi|239742130 PREDICTED: hypothetical protein XP_002342439 [Homo
sapiens]
Length = 218
Score = 29.3 bits (64), Expect = 3.5
Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 12/69 (17%)
Query: 194 PGPETAAFIERL--EMEQAQKAKNPQEQK-----SFFAKYWHIILGGAVLLTALRP--AA 244
PGP T F + +EQ ++ K+P ++ FFA+ + + RP A
Sbjct: 110 PGPATPDFYALVAQRLEQQEQLKSPPSKRISLASGFFARLVELFCSRE---DSSRPSRAC 166
Query: 245 PGPAPPPQE 253
PGP PP QE
Sbjct: 167 PGPPPPSQE 175
>gi|223972612 Crm, cramped-like [Homo sapiens]
Length = 1269
Score = 28.9 bits (63), Expect = 4.5
Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 1/31 (3%)
Query: 22 PSRARGSGCRAGTGARGAGAEGREGEACGTV 52
P A GSG G+G RG GAEG G + G V
Sbjct: 98 PPSAVGSGNAGGSGPRGKGAEG-GGSSSGNV 127
>gi|239755267 PREDICTED: hypothetical protein [Homo sapiens]
Length = 94
Score = 28.9 bits (63), Expect = 4.5
Identities = 20/52 (38%), Positives = 23/52 (44%), Gaps = 5/52 (9%)
Query: 4 ASAGATRLLLLLLMAVAA-PSRARGSG----CRAGTGARGAGAEGREGEACG 50
+S G +L L VA P + G C AGT GAGA G GE G
Sbjct: 11 SSPGPRAVLQFLAFGVAPRPPAPQNPGFFSVCAAGTAQAGAGAPGLRGEGLG 62
>gi|239749560 PREDICTED: hypothetical protein XP_002347086 [Homo
sapiens]
Length = 443
Score = 28.9 bits (63), Expect = 4.5
Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 7/54 (12%)
Query: 2 AAASAGATRLLLLLLMAVA-------APSRARGSGCRAGTGARGAGAEGREGEA 48
A ASAG+ R L + A RG G RAG G RGA E G A
Sbjct: 61 ALASAGSRRCAPAALCSSGGCALTRRAACGGRGGGTRAGQGGRGAWGEAPVGSA 114
Score = 28.1 bits (61), Expect = 7.7
Identities = 16/26 (61%), Positives = 16/26 (61%), Gaps = 1/26 (3%)
Query: 24 RARGSGCRAGTGAR-GAGAEGREGEA 48
R RG G RAGTG R G GA G G A
Sbjct: 286 RQRGGGVRAGTGPRSGDGAFGTLGSA 311
>gi|239743710 PREDICTED: hypothetical protein XP_002342931 [Homo
sapiens]
Length = 522
Score = 28.9 bits (63), Expect = 4.5
Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 7/54 (12%)
Query: 2 AAASAGATRLLLLLLMAVA-------APSRARGSGCRAGTGARGAGAEGREGEA 48
A ASAG+ R L + A RG G RAG G RGA E G A
Sbjct: 61 ALASAGSRRCAPAALCSSGGCALTRRAACGGRGGGTRAGQGGRGAWGEAPVGSA 114
Score = 28.1 bits (61), Expect = 7.7
Identities = 16/26 (61%), Positives = 16/26 (61%), Gaps = 1/26 (3%)
Query: 24 RARGSGCRAGTGAR-GAGAEGREGEA 48
R RG G RAGTG R G GA G G A
Sbjct: 286 RQRGGGVRAGTGPRSGDGAFGTLGSA 311
>gi|214010185 amyloid beta (A4) precursor-like protein 2 isoform 4
[Homo sapiens]
Length = 522
Score = 28.9 bits (63), Expect = 4.5
Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 7/57 (12%)
Query: 3 AASAGATRLLLLLLMAVAAPSRA-----RGSGCRAGTGARGAGAEGREGEACGTVGL 54
AA+A RLLLLLL+ + AP+ A AGTG A AE + CG + +
Sbjct: 7 AAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGF--AVAEPQIAMFCGKLNM 61
>gi|214010183 amyloid beta (A4) precursor-like protein 2 isoform 3
[Homo sapiens]
Length = 695
Score = 28.9 bits (63), Expect = 4.5
Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 7/57 (12%)
Query: 3 AASAGATRLLLLLLMAVAAPSRA-----RGSGCRAGTGARGAGAEGREGEACGTVGL 54
AA+A RLLLLLL+ + AP+ A AGTG A AE + CG + +
Sbjct: 7 AAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGF--AVAEPQIAMFCGKLNM 61
>gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2
[Homo sapiens]
Length = 751
Score = 28.9 bits (63), Expect = 4.5
Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 7/57 (12%)
Query: 3 AASAGATRLLLLLLMAVAAPSRA-----RGSGCRAGTGARGAGAEGREGEACGTVGL 54
AA+A RLLLLLL+ + AP+ A AGTG A AE + CG + +
Sbjct: 7 AAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGF--AVAEPQIAMFCGKLNM 61
>gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1
[Homo sapiens]
Length = 763
Score = 28.9 bits (63), Expect = 4.5
Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 7/57 (12%)
Query: 3 AASAGATRLLLLLLMAVAAPSRA-----RGSGCRAGTGARGAGAEGREGEACGTVGL 54
AA+A RLLLLLL+ + AP+ A AGTG A AE + CG + +
Sbjct: 7 AAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGF--AVAEPQIAMFCGKLNM 61
>gi|24308458 Lix1 homolog (mouse) like [Homo sapiens]
Length = 337
Score = 28.5 bits (62), Expect = 5.9
Identities = 12/19 (63%), Positives = 12/19 (63%)
Query: 233 GAVLLTALRPAAPGPAPPP 251
GA TA PA P PAPPP
Sbjct: 30 GAAAATATPPAGPPPAPPP 48
>gi|8922567 hypothetical protein LOC55194 [Homo sapiens]
Length = 165
Score = 28.5 bits (62), Expect = 5.9
Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 13/66 (19%)
Query: 172 EVEDVDLELFNTSVQLQPPTTAPGPETAA----------FIERLEMEQAQKAKNPQEQKS 221
E ED D + +T +L P T PGPE +A F E+E+AQ+ +E++
Sbjct: 74 EPEDDDEDEEDTVTRLGPDDTLPGPELSAEPDGPLNVNVFTSAEELERAQRL---EERER 130
Query: 222 FFAKYW 227
+ W
Sbjct: 131 ILREIW 136
>gi|5032099 smoothened [Homo sapiens]
Length = 787
Score = 28.1 bits (61), Expect = 7.7
Identities = 28/90 (31%), Positives = 32/90 (35%), Gaps = 4/90 (4%)
Query: 13 LLLLMAVAAPSR-ARGSGCRAGTGARGAGAEGREGEACGTVGLLLEHSFEIDDSANFRKR 71
LLLL+ + P R A SG G G R AG R A L H R
Sbjct: 17 LLLLLLLGDPGRGAASSGNATGPGPRSAGGSARRSAAVTGPPPPLSHCGRAAPCEPLRYN 76
Query: 72 ---GSLLWNQQDGTLSLSQRQLSEEERGRL 98
GS+L TL EE G+L
Sbjct: 77 VCLGSVLPYGATSTLLAGDSDSQEEAHGKL 106
>gi|126090909 engrailed homeobox 1 [Homo sapiens]
Length = 392
Score = 28.1 bits (61), Expect = 7.7
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
Query: 2 AAASAGATRLLLLLLMAVAAPSRARGSGCRAGTGARGAGAEGREGEACGTVGLLL 56
AAA+A A + A A PS G G G G+ GA+G + G +LL
Sbjct: 200 AAAAAAAAAVAAAAAAAAAKPSDTGGGGSGGGAGS--PGAQGTKYPEHGNPAILL 252
>gi|19924103 synapsin II isoform IIa [Homo sapiens]
Length = 582
Score = 28.1 bits (61), Expect = 7.7
Identities = 24/69 (34%), Positives = 26/69 (37%), Gaps = 10/69 (14%)
Query: 184 SVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWHIILGGAVLLTALRPA 243
S PPT +PGPE Q A P SFF+ L AV TA
Sbjct: 46 SASAAPPTASPGPERRP--PPASAPAPQPAPTPSVGSSFFSS-----LSQAVKQTAASAG 98
Query: 244 ---APGPAP 249
AP PAP
Sbjct: 99 LVDAPAPAP 107
>gi|114145479 neuroepithelial cell transforming gene 1 isoform 1
[Homo sapiens]
Length = 596
Score = 28.1 bits (61), Expect = 7.7
Identities = 27/103 (26%), Positives = 39/103 (37%), Gaps = 18/103 (17%)
Query: 31 RAGTGARGAGAEGREGEACGTVGLLLEHSFEIDDSANF--------------RKRGSLLW 76
R A G EG G + T G L+ + ++F RKR
Sbjct: 15 RRSRRASGLSTEGATGPSADTSGSELDGRCSLRRGSSFTFLTPGPNWDFTLKRKRRE--- 71
Query: 77 NQQDGTLSLSQRQLSEEERGRLRDVAALNGLYRVRIPRRPGAL 119
+ D +SLS L E R+R +A + L + P R GA+
Sbjct: 72 -KDDDVVSLSSLDLKEPSNKRVRPLARVTSLANLISPVRNGAV 113
>gi|19924101 synapsin II isoform IIb [Homo sapiens]
Length = 478
Score = 28.1 bits (61), Expect = 7.7
Identities = 24/69 (34%), Positives = 26/69 (37%), Gaps = 10/69 (14%)
Query: 184 SVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWHIILGGAVLLTALRPA 243
S PPT +PGPE Q A P SFF+ L AV TA
Sbjct: 46 SASAAPPTASPGPERRP--PPASAPAPQPAPTPSVGSSFFSS-----LSQAVKQTAASAG 98
Query: 244 ---APGPAP 249
AP PAP
Sbjct: 99 LVDAPAPAP 107
>gi|84781739 leucine-rich repeats and transmembrane domains 2 [Homo
sapiens]
Length = 370
Score = 28.1 bits (61), Expect = 7.7
Identities = 21/70 (30%), Positives = 28/70 (40%), Gaps = 12/70 (17%)
Query: 163 THPGGCRGHEVEDVDLELFNTSVQLQ------------PPTTAPGPETAAFIERLEMEQA 210
T P RG ++ V +E+FN QL+ PP T PE A E E
Sbjct: 229 TLPKELRGKDMRMVPMEMFNYCSQLEDENSSAGLDIPGPPCTKASPEPAKPKPGAEPEPE 288
Query: 211 QKAKNPQEQK 220
PQ+Q+
Sbjct: 289 PSTACPQKQR 298
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,320,004
Number of Sequences: 37866
Number of extensions: 552015
Number of successful extensions: 3347
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3328
Number of HSP's gapped (non-prelim): 30
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.