SMO 31532

Name: SMO	Sequence: fasta or formatted (787aa)		NCBI GI: 5032099
Description: smoothened		Referenced in: Hedgehog and Related Pathways Wnt Signals
Composition: Amino acid Percentage Count Longest homopolymer A alanine 9.4 74 3 C cysteine 3.3 26 1 D aspartate 3.7 29 2 E glutamate 4.7 37 2 F phenylalanine 4.7 37 2 G glycine 7.8 61 2 H histidine 1.9 15 1 I isoleucine 4.2 33 2 K lysine 3.7 29 3 L leucine 10.3 81 7 M methionine 1.9 15 1 N asparagine 3.2 25 1 P proline 8.3 65 4 Q glutamine 3.3 26 1 R arginine 6.2 49 2 S serine 6.6 52 2 T threonine 5.5 43 2 V valine 6.7 53 2 W tryptophan 2.4 19 1 Y tyrosine 2.3 18 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 smoothened FZD1 0.105 frizzled 1 FZD5 0.098 frizzled 5 precursor FZD7 0.098 frizzled 7 FZD2 0.093 frizzled 2 FZD4 0.092 frizzled 4 FZD3 0.088 frizzled 3 FZD10 0.086 frizzled 10 FZD6 0.086 frizzled 6 FZD8 0.083 frizzled 8 FZD9 0.080 frizzled 9 SFRP1 0.015 secreted frizzled-related protein 1 CPZ 0.014 carboxypeptidase Z isoform 2 precursor CPZ 0.014 carboxypeptidase Z isoform 1 SFRP5 0.012 secreted frizzled-related protein 5 SFRP4 0.011 secreted frizzled-related protein 4 FRZB 0.010 frizzled-related protein MFRP 0.010 membrane frizzled-related protein MLL4 0.010 myeloid/lymphoid or mixed-lineage leukemia 4 CORIN 0.009 corin SYNPO2L 0.009 synaptopodin 2-like isoform a KDM6B 0.009 lysine (K)-specific demethylase 6B FLJ22184 0.009 PREDICTED: hypothetical protein FLJ22184 FLJ22184 0.008 PREDICTED: hypothetical protein FLJ22184 FLJ22184 0.008 PREDICTED: hypothetical protein LOC80164 KIAA1949 0.008 phostensin KIAA1949 0.008 phostensin WAS 0.008 Wiskott-Aldrich syndrome protein PCDH15 0.008 protocadherin 15 isoform CD1-4 precursor PCDH15 0.008 protocadherin 15 isoform CD1-10 precursor Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.