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Search of human proteins with 8923582
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923582 zinc finger protein 446 [Homo sapiens]
(450 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923582 zinc finger protein 446 [Homo sapiens] 957 0.0
gi|56118254 zinc finger protein 18 [Homo sapiens] 210 2e-54
gi|197383784 zinc finger protein 213 [Homo sapiens] 206 5e-53
gi|32698678 zinc finger protein 213 [Homo sapiens] 206 5e-53
gi|37622341 zinc finger protein 42 isoform 2 [Homo sapiens] 201 9e-52
gi|37622345 zinc finger protein 42 isoform 1 [Homo sapiens] 201 9e-52
gi|21483182 zinc finger with KRAB and SCAN domains 5 [Homo sapiens] 196 3e-50
gi|11036642 zinc finger with KRAB and SCAN domains 5 [Homo sapiens] 196 3e-50
gi|57863253 zinc finger protein 500 [Homo sapiens] 196 4e-50
gi|31543980 zinc finger protein 263 [Homo sapiens] 187 2e-47
gi|171906553 zinc finger with KRAB and SCAN domains 3 [Homo sapi... 182 5e-46
gi|55769564 zinc finger protein 36 [Homo sapiens] 182 5e-46
gi|64368880 zinc finger and SCAN domain containing 25 [Homo sapi... 181 2e-45
gi|56699475 zinc finger protein 202 [Homo sapiens] 180 3e-45
gi|17738285 zinc finger with KRAB and SCAN domains 4 [Homo sapiens] 174 2e-43
gi|224493912 zinc finger and SCAN domain containing 18 isoform 3... 172 7e-43
gi|226371704 zinc finger and SCAN domain containing 18 isoform 3... 172 7e-43
gi|224493905 zinc finger and SCAN domain containing 18 isoform 1... 172 7e-43
gi|32813445 zinc finger and SCAN domain containing 22 [Homo sapi... 171 9e-43
gi|41152070 zinc finger protein 75 [Homo sapiens] 169 4e-42
gi|47716687 zinc finger protein 167 isoform 1 [Homo sapiens] 164 2e-40
gi|27544931 zinc finger protein 38 [Homo sapiens] 161 1e-39
gi|14249386 zinc finger protein 496 [Homo sapiens] 159 5e-39
gi|4508007 zinc finger protein 174 isoform a [Homo sapiens] 158 8e-39
gi|254281232 zinc finger and SCAN domain containing 12 [Homo sap... 156 4e-38
gi|56699473 zinc finger protein 192 [Homo sapiens] 155 7e-38
gi|194328783 zinc finger protein 287 [Homo sapiens] 138 9e-33
gi|68800230 zinc finger protein 197 isoform 2 [Homo sapiens] 130 2e-30
gi|19743801 zinc finger protein 274 isoform c [Homo sapiens] 130 3e-30
gi|7706507 zinc finger protein 274 isoform a [Homo sapiens] 130 3e-30
>gi|8923582 zinc finger protein 446 [Homo sapiens]
Length = 450
Score = 957 bits (2474), Expect = 0.0
Identities = 450/450 (100%), Positives = 450/450 (100%)
Query: 1 MPSPLGPPCLPVMDPETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAH 60
MPSPLGPPCLPVMDPETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAH
Sbjct: 1 MPSPLGPPCLPVMDPETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAH 60
Query: 61 SKEQMLEMLVLEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVL 120
SKEQMLEMLVLEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVL
Sbjct: 61 SKEQMLEMLVLEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVL 120
Query: 121 KQEVLPAAQKTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPS 180
KQEVLPAAQKTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPS
Sbjct: 121 KQEVLPAAQKTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPS 180
Query: 181 SPPLAAQSPEGNHGHQEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLP 240
SPPLAAQSPEGNHGHQEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLP
Sbjct: 181 SPPLAAQSPEGNHGHQEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLP 240
Query: 241 PHQPEAQAQSELGMLLTGTGVCRSLRSGNESEGPPGCPEAQPPQGPGPAAWEGLSGAATP 300
PHQPEAQAQSELGMLLTGTGVCRSLRSGNESEGPPGCPEAQPPQGPGPAAWEGLSGAATP
Sbjct: 241 PHQPEAQAQSELGMLLTGTGVCRSLRSGNESEGPPGCPEAQPPQGPGPAAWEGLSGAATP 300
Query: 301 APTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGV 360
APTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGV
Sbjct: 301 APTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGV 360
Query: 361 QSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQ 420
QSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQ
Sbjct: 361 QSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQ 420
Query: 421 RRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
RRHFCSDCGRAFDWKSQLVIHRKGHRPEVP
Sbjct: 421 RRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
>gi|56118254 zinc finger protein 18 [Homo sapiens]
Length = 549
Score = 210 bits (534), Expect = 2e-54
Identities = 168/519 (32%), Positives = 222/519 (42%), Gaps = 92/519 (17%)
Query: 19 LEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTL 78
L PETAR FR F YQ ++GP E L +LR+LC QWLQPE H+KEQ+LE+L+LEQFL L
Sbjct: 34 LSSPETARQLFRQFRYQVMSGPHETLKQLRKLCFQWLQPEVHTKEQILEILMLEQFLTIL 93
Query: 79 PPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEP---L 135
P EIQ WVR Q PGS EEA LVE L+ DP +L WI+ VL Q++L ++K E P +
Sbjct: 94 PGEIQMWVRKQCPGSGEEAVTLVESLKGDPQRLWQWISIQVLGQDIL--SEKMESPSCQV 151
Query: 136 GSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGH 195
G P V G +++ LS VKEE + + + +S P E
Sbjct: 152 GEVEPHLEVVPQELGLENSSSGPGELLSHIVKEESDTEAELALAASQPARL---EERLIR 208
Query: 196 QEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVS-LGLPPHQPEAQAQSELGM 254
+ S P QE+W LD +QKE YWD MLE YG +VS G+ + + E G
Sbjct: 209 DQDLGASLLPAAPQEQWRQLDSTQKEQYWDLMLETYGKMVSGAGISHPKSDLTNSIEFGE 268
Query: 255 LLTG----------TGVCRSLRSGNE---------------------------------- 270
L G C R N+
Sbjct: 269 ELAGIYLHVNEKIPRPTCIGDRQENDKENLNLENHRDQELLHASCQASGEVPSQASLRGF 328
Query: 271 -SEGPPGC-------PEA-QPPQGPGP----AAWEGLSGAATPAPTVRPGTPPVPTQPTP 317
+E PGC PEA Q Q G + E +S P + + T
Sbjct: 329 FTEDEPGCFGEGENLPEALQNIQDEGTGEQLSPQERISEKQLGQHLPNPHSGEMSTMWLE 388
Query: 318 AETRLEPAATPRKPY-----TCEQCGRGFDWKSVFVIHHRTHT----------------S 356
+ PR P TC +CG+ F S + H RTHT S
Sbjct: 389 EKRETSQKGQPRAPMAQKLPTCRECGKTFYRNSQLIFHQRTHTGETYFQCTICKKAFLRS 448
Query: 357 GPGVQSPGLATGESTEKPPQGEVAFP-----HHPRRSLTGPRSYPCEECGCSFSWKSQLV 411
V+ TGE K F H + TG + Y C C SF +S
Sbjct: 449 SDFVKHQRTHTGEKPCKCDYCGKGFSDFSGLRHHEKIHTGEKPYKCPICEKSFIQRSNFN 508
Query: 412 IHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
H++ HTG++ + CS CG++F W S L H++ H + P
Sbjct: 509 RHQRVHTGEKPYKCSHCGKSFSWSSSLDKHQRSHLGKKP 547
>gi|197383784 zinc finger protein 213 [Homo sapiens]
Length = 459
Score = 206 bits (523), Expect = 5e-53
Identities = 157/454 (34%), Positives = 210/454 (46%), Gaps = 89/454 (19%)
Query: 21 EPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPP 80
+ E R RFR FCY +V GP EA ++L ELCC+WL+PE +KEQ+LE+LVLEQFL LP
Sbjct: 40 DSEACRQRFRQFCYGDVHGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPG 99
Query: 81 EIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEPLGSPHP 140
EIQ WVR Q PGS EEA ALVE LQ P + W +Q+V P
Sbjct: 100 EIQGWVREQHPGSGEEAVALVEDLQKQP--VKAW------RQDV-------------PSE 138
Query: 141 SGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGHQEPAS 200
E+ G G Q T +V + P+V ++ + S+ P A EG G E
Sbjct: 139 EAEPEAAGRGSQATGPPPTV----GARRRPSVPQEQHSHSAQP-PALLKEGRPG--ETTD 191
Query: 201 TSF----HPPRI---------QEEWGLLDRSQKELYWDAMLE-KYGTVVSLGLPPHQPEA 246
T F H P +EEWG LD +Q++L+WD E T + GL ++
Sbjct: 192 TCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKRENSRNTTLGFGLKGQSEKS 251
Query: 247 QAQSELGML--LTGTGVCRSLRSGNESEGPPGCPEAQPPQGPGPAAWEGLS---GAATPA 301
Q + ++ TG+ V S S E+E AWE + A P
Sbjct: 252 LLQEMVPVVPGQTGSDVTVSW-SPEEAE-----------------AWESENRPRAALGPV 293
Query: 302 PTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQ 361
R G P P R KP++C QCG+ F W S H RTH
Sbjct: 294 VGARRGRP-------PTRRRQFRDLAAEKPHSCGQCGKRFRWGSDLARHQRTH------- 339
Query: 362 SPGLATGESTEKPPQGEVAFPH-----HPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKS 416
TGE K P+ + +F + TG + + C ECG SFS + L H++
Sbjct: 340 -----TGEKPHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRI 394
Query: 417 HTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
HTG++ CSDCG++F +S L+ HR+ H E P
Sbjct: 395 HTGEKPFGCSDCGKSFSLRSYLLDHRRVHTGERP 428
>gi|32698678 zinc finger protein 213 [Homo sapiens]
Length = 459
Score = 206 bits (523), Expect = 5e-53
Identities = 157/454 (34%), Positives = 210/454 (46%), Gaps = 89/454 (19%)
Query: 21 EPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPP 80
+ E R RFR FCY +V GP EA ++L ELCC+WL+PE +KEQ+LE+LVLEQFL LP
Sbjct: 40 DSEACRQRFRQFCYGDVHGPHEAFSQLWELCCRWLRPELRTKEQILELLVLEQFLTVLPG 99
Query: 81 EIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEPLGSPHP 140
EIQ WVR Q PGS EEA ALVE LQ P + W +Q+V P
Sbjct: 100 EIQGWVREQHPGSGEEAVALVEDLQKQP--VKAW------RQDV-------------PSE 138
Query: 141 SGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGHQEPAS 200
E+ G G Q T +V + P+V ++ + S+ P A EG G E
Sbjct: 139 EAEPEAAGRGSQATGPPPTV----GARRRPSVPQEQHSHSAQP-PALLKEGRPG--ETTD 191
Query: 201 TSF----HPPRI---------QEEWGLLDRSQKELYWDAMLE-KYGTVVSLGLPPHQPEA 246
T F H P +EEWG LD +Q++L+WD E T + GL ++
Sbjct: 192 TCFVSGVHGPVALGDIPFYFSREEWGTLDPAQRDLFWDIKRENSRNTTLGFGLKGQSEKS 251
Query: 247 QAQSELGML--LTGTGVCRSLRSGNESEGPPGCPEAQPPQGPGPAAWEGLS---GAATPA 301
Q + ++ TG+ V S S E+E AWE + A P
Sbjct: 252 LLQEMVPVVPGQTGSDVTVSW-SPEEAE-----------------AWESENRPRAALGPV 293
Query: 302 PTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQ 361
R G P P R KP++C QCG+ F W S H RTH
Sbjct: 294 VGARRGRP-------PTRRRQFRDLAAEKPHSCGQCGKRFRWGSDLARHQRTH------- 339
Query: 362 SPGLATGESTEKPPQGEVAFPH-----HPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKS 416
TGE K P+ + +F + TG + + C ECG SFS + L H++
Sbjct: 340 -----TGEKPHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLADHQRI 394
Query: 417 HTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
HTG++ CSDCG++F +S L+ HR+ H E P
Sbjct: 395 HTGEKPFGCSDCGKSFSLRSYLLDHRRVHTGERP 428
>gi|37622341 zinc finger protein 42 isoform 2 [Homo sapiens]
Length = 734
Score = 201 bits (512), Expect = 9e-52
Identities = 167/493 (33%), Positives = 218/493 (44%), Gaps = 93/493 (18%)
Query: 2 PSPLGPPCLPVMDPETTLEE------PETARLRFRGFCYQEVAGPREALARLRELCCQWL 55
P GP + + D E E PE ARLRFR F Y+E GP+EALA+LRELC QWL
Sbjct: 14 PEDEGPVMVKLEDSEEEGEAALWDPGPEAARLRFRCFRYEEATGPQEALAQLRELCRQWL 73
Query: 56 QPEAHSKEQMLEMLVLEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWI 115
+PE SKEQMLE+LVLEQFLG LPPEIQA V+GQRPGSPEEAAALV+GL+ +PG W+
Sbjct: 74 RPEVRSKEQMLELLVLEQFLGALPPEIQARVQGQRPGSPEEAAALVDGLRREPGGPRRWV 133
Query: 116 TAHVLKQEVLPAAQKTEEPLGSPHPSGTVESPGEGPQDT-RIEGSVQLSCSVKEEPNVDG 174
T V QEVL ++K E P P +P GP+ R L VKEE V
Sbjct: 134 TVQVQGQEVL--SEKMEPSSFQPLPETEPPTPEPGPKTPPRTMQESPLGLQVKEESEVTE 191
Query: 175 QEVAPSSPPLAAQS----------------------PEGNHGHQEPASTSFHPPRI-QEE 211
S PLAA P G + P S HP + EE
Sbjct: 192 DSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSKTGPEGP-SWREHPRALWHEE 250
Query: 212 WGLLDRSQKELYWDAMLEKYGTVV-------SLGLPPHQPEAQAQSELGMLLTGTGVCRS 264
G + L ++ G+V LG+ + Q+ S G G
Sbjct: 251 AGGIFSPGFALQLGSISAGPGSVSPHLHVPWDLGMAGLSGQIQSPSREG----GFAHALL 306
Query: 265 LRSGNESEGPPGCPEAQPPQGPGPAA----WEGLSGAATPAPT-----VRPGTPPVPTQP 315
L S SE P + P +G GPA W G + P+ VR G V +
Sbjct: 307 LPSDLRSEQDP--TDEDPCRGVGPALITTRWRSPRGRSRGRPSTGGGVVRGGRCDVCGKV 364
Query: 316 TPAETRL---EPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTE 372
+ L + T +P+ C +CGR F S + H THT
Sbjct: 365 FSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRHQLTHTE---------------- 408
Query: 373 KPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAF 432
R + C +CG F ++L HR+ HTG++ C++CG++F
Sbjct: 409 -------------------ERPFVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSF 449
Query: 433 DWKSQLVIHRKGH 445
+S L+ H++ H
Sbjct: 450 RQRSNLLQHQRIH 462
Score = 80.1 bits (196), Expect = 4e-15
Identities = 51/144 (35%), Positives = 69/144 (47%), Gaps = 10/144 (6%)
Query: 307 GTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLA 366
G PP P PA A P P+ C +C F ++V + H HT G +S G
Sbjct: 463 GDPPGPGAKPPAPPG---APEPPGPFPCSECRESFARRAVLLEHQAVHT---GDKSFGCV 516
Query: 367 TGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCS 426
E E+ + V H RR +G R + C ECG SF +S L HR+ HTG+R C+
Sbjct: 517 --ECGERFGRRSVLLQH--RRVHSGERPFACAECGQSFRQRSNLTQHRRIHTGERPFACA 572
Query: 427 DCGRAFDWKSQLVIHRKGHRPEVP 450
+CG+AF + L H + H E P
Sbjct: 573 ECGKAFRQRPTLTQHLRVHTGEKP 596
Score = 77.8 bits (190), Expect = 2e-14
Identities = 42/124 (33%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T KP+ C +CG+ F + H RTHT G + +V+ +
Sbjct: 592 TGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLGFT-------QVSRLTEHQ 644
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHR 446
R TG R + C ECG SF + L HR+ HTG+R + C +CG+AF + L H + HR
Sbjct: 645 RIHTGERPFACPECGQSFRQHANLTQHRRIHTGERPYACPECGKAFRQRPTLTQHLRTHR 704
Query: 447 PEVP 450
E P
Sbjct: 705 REKP 708
Score = 76.3 bits (186), Expect = 5e-14
Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 10/134 (7%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTH--TSGPGVQSPGLATGESTEKPPQGEVAFPHH 384
T +P+ C +CG+ F +S + H R H GPG + P P
Sbjct: 435 TGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAKPPAPPGAPEPPGPFPCSECRESF 494
Query: 385 PRRSL--------TGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKS 436
RR++ TG +S+ C ECG F +S L+ HR+ H+G+R C++CG++F +S
Sbjct: 495 ARRAVLLEHQAVHTGDKSFGCVECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRS 554
Query: 437 QLVIHRKGHRPEVP 450
L HR+ H E P
Sbjct: 555 NLTQHRRIHTGERP 568
Score = 75.5 bits (184), Expect = 9e-14
Identities = 45/134 (33%), Positives = 60/134 (44%), Gaps = 17/134 (12%)
Query: 320 TRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEV 379
TR + T KPY C +CG GF S H R HT GE P+
Sbjct: 613 TRHQRTHTGEKPYHCGECGLGFTQVSRLTEHQRIHT------------GERPFACPECGQ 660
Query: 380 AFPHHP-----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDW 434
+F H RR TG R Y C ECG +F + L H ++H ++ C DCGR F
Sbjct: 661 SFRQHANLTQHRRIHTGERPYACPECGKAFRQRPTLTQHLRTHRREKPFACQDCGRRFHQ 720
Query: 435 KSQLVIHRKGHRPE 448
++L+ H++ H E
Sbjct: 721 STKLIQHQRVHSAE 734
Score = 72.8 bits (177), Expect = 6e-13
Identities = 57/176 (32%), Positives = 77/176 (43%), Gaps = 28/176 (15%)
Query: 286 PGPAAWEGLSGAATPAPTVRPGTPPVPTQPTPAETR---------LEPAA--TPRKPYTC 334
PGP GA PAP PG P P +E R LE A T K + C
Sbjct: 466 PGP-------GAKPPAP---PGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGC 515
Query: 335 EQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRS 394
+CG F +SV + H R H+ + P A E + Q H RR TG R
Sbjct: 516 VECGERFGRRSVLLQHRRVHSG----ERP-FACAECGQSFRQRSNLTQH--RRIHTGERP 568
Query: 395 YPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
+ C ECG +F + L H + HTG++ C +CG+ F + +L H++ H E P
Sbjct: 569 FACAECGKAFRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKP 624
>gi|37622345 zinc finger protein 42 isoform 1 [Homo sapiens]
Length = 734
Score = 201 bits (512), Expect = 9e-52
Identities = 167/493 (33%), Positives = 218/493 (44%), Gaps = 93/493 (18%)
Query: 2 PSPLGPPCLPVMDPETTLEE------PETARLRFRGFCYQEVAGPREALARLRELCCQWL 55
P GP + + D E E PE ARLRFR F Y+E GP+EALA+LRELC QWL
Sbjct: 14 PEDEGPVMVKLEDSEEEGEAALWDPGPEAARLRFRCFRYEEATGPQEALAQLRELCRQWL 73
Query: 56 QPEAHSKEQMLEMLVLEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWI 115
+PE SKEQMLE+LVLEQFLG LPPEIQA V+GQRPGSPEEAAALV+GL+ +PG W+
Sbjct: 74 RPEVRSKEQMLELLVLEQFLGALPPEIQARVQGQRPGSPEEAAALVDGLRREPGGPRRWV 133
Query: 116 TAHVLKQEVLPAAQKTEEPLGSPHPSGTVESPGEGPQDT-RIEGSVQLSCSVKEEPNVDG 174
T V QEVL ++K E P P +P GP+ R L VKEE V
Sbjct: 134 TVQVQGQEVL--SEKMEPSSFQPLPETEPPTPEPGPKTPPRTMQESPLGLQVKEESEVTE 191
Query: 175 QEVAPSSPPLAAQS----------------------PEGNHGHQEPASTSFHPPRI-QEE 211
S PLAA P G + P S HP + EE
Sbjct: 192 DSDFLESGPLAATQESVPTLLPEEAQRCGTVLDQIFPHSKTGPEGP-SWREHPRALWHEE 250
Query: 212 WGLLDRSQKELYWDAMLEKYGTVV-------SLGLPPHQPEAQAQSELGMLLTGTGVCRS 264
G + L ++ G+V LG+ + Q+ S G G
Sbjct: 251 AGGIFSPGFALQLGSISAGPGSVSPHLHVPWDLGMAGLSGQIQSPSREG----GFAHALL 306
Query: 265 LRSGNESEGPPGCPEAQPPQGPGPAA----WEGLSGAATPAPT-----VRPGTPPVPTQP 315
L S SE P + P +G GPA W G + P+ VR G V +
Sbjct: 307 LPSDLRSEQDP--TDEDPCRGVGPALITTRWRSPRGRSRGRPSTGGGVVRGGRCDVCGKV 364
Query: 316 TPAETRL---EPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTE 372
+ L + T +P+ C +CGR F S + H THT
Sbjct: 365 FSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRHQLTHTE---------------- 408
Query: 373 KPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAF 432
R + C +CG F ++L HR+ HTG++ C++CG++F
Sbjct: 409 -------------------ERPFVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSF 449
Query: 433 DWKSQLVIHRKGH 445
+S L+ H++ H
Sbjct: 450 RQRSNLLQHQRIH 462
Score = 80.1 bits (196), Expect = 4e-15
Identities = 51/144 (35%), Positives = 69/144 (47%), Gaps = 10/144 (6%)
Query: 307 GTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLA 366
G PP P PA A P P+ C +C F ++V + H HT G +S G
Sbjct: 463 GDPPGPGAKPPAPPG---APEPPGPFPCSECRESFARRAVLLEHQAVHT---GDKSFGCV 516
Query: 367 TGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCS 426
E E+ + V H RR +G R + C ECG SF +S L HR+ HTG+R C+
Sbjct: 517 --ECGERFGRRSVLLQH--RRVHSGERPFACAECGQSFRQRSNLTQHRRIHTGERPFACA 572
Query: 427 DCGRAFDWKSQLVIHRKGHRPEVP 450
+CG+AF + L H + H E P
Sbjct: 573 ECGKAFRQRPTLTQHLRVHTGEKP 596
Score = 77.8 bits (190), Expect = 2e-14
Identities = 42/124 (33%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T KP+ C +CG+ F + H RTHT G + +V+ +
Sbjct: 592 TGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLGFT-------QVSRLTEHQ 644
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHR 446
R TG R + C ECG SF + L HR+ HTG+R + C +CG+AF + L H + HR
Sbjct: 645 RIHTGERPFACPECGQSFRQHANLTQHRRIHTGERPYACPECGKAFRQRPTLTQHLRTHR 704
Query: 447 PEVP 450
E P
Sbjct: 705 REKP 708
Score = 76.3 bits (186), Expect = 5e-14
Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 10/134 (7%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTH--TSGPGVQSPGLATGESTEKPPQGEVAFPHH 384
T +P+ C +CG+ F +S + H R H GPG + P P
Sbjct: 435 TGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAKPPAPPGAPEPPGPFPCSECRESF 494
Query: 385 PRRSL--------TGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKS 436
RR++ TG +S+ C ECG F +S L+ HR+ H+G+R C++CG++F +S
Sbjct: 495 ARRAVLLEHQAVHTGDKSFGCVECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRS 554
Query: 437 QLVIHRKGHRPEVP 450
L HR+ H E P
Sbjct: 555 NLTQHRRIHTGERP 568
Score = 75.5 bits (184), Expect = 9e-14
Identities = 45/134 (33%), Positives = 60/134 (44%), Gaps = 17/134 (12%)
Query: 320 TRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEV 379
TR + T KPY C +CG GF S H R HT GE P+
Sbjct: 613 TRHQRTHTGEKPYHCGECGLGFTQVSRLTEHQRIHT------------GERPFACPECGQ 660
Query: 380 AFPHHP-----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDW 434
+F H RR TG R Y C ECG +F + L H ++H ++ C DCGR F
Sbjct: 661 SFRQHANLTQHRRIHTGERPYACPECGKAFRQRPTLTQHLRTHRREKPFACQDCGRRFHQ 720
Query: 435 KSQLVIHRKGHRPE 448
++L+ H++ H E
Sbjct: 721 STKLIQHQRVHSAE 734
Score = 72.8 bits (177), Expect = 6e-13
Identities = 57/176 (32%), Positives = 77/176 (43%), Gaps = 28/176 (15%)
Query: 286 PGPAAWEGLSGAATPAPTVRPGTPPVPTQPTPAETR---------LEPAA--TPRKPYTC 334
PGP GA PAP PG P P +E R LE A T K + C
Sbjct: 466 PGP-------GAKPPAP---PGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGC 515
Query: 335 EQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRS 394
+CG F +SV + H R H+ + P A E + Q H RR TG R
Sbjct: 516 VECGERFGRRSVLLQHRRVHSG----ERP-FACAECGQSFRQRSNLTQH--RRIHTGERP 568
Query: 395 YPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
+ C ECG +F + L H + HTG++ C +CG+ F + +L H++ H E P
Sbjct: 569 FACAECGKAFRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKP 624
>gi|21483182 zinc finger with KRAB and SCAN domains 5 [Homo sapiens]
Length = 839
Score = 196 bits (499), Expect = 3e-50
Identities = 154/434 (35%), Positives = 206/434 (47%), Gaps = 39/434 (8%)
Query: 23 ETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPPEI 82
ET RFR F Y E +GPREAL++LR LCC+WL+PE H+KEQ+LE+LVLEQFL LP E
Sbjct: 47 ETFYQRFRHFQYHEASGPREALSQLRVLCCEWLRPELHTKEQILELLVLEQFLTILPEEF 106
Query: 83 QAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTE---EPLGSPH 139
Q WVR P S EEA A++E +Q + + I A +VLP T + SPH
Sbjct: 107 QPWVREHHPESGEEAVAVIENIQRELEERRQQIVA---CPDVLPRKMATPGAVQESCSPH 163
Query: 140 PSGTVESPGEGPQDTR-IEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGHQEP 198
P P + PQ R +E + V P D QE+ S +Q +
Sbjct: 164 PLTVDTQPEQAPQKPRLLEENALPVLQVPSLPLKDSQELTASLLSTGSQKLVKIEEVADV 223
Query: 199 ASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQPEAQAQSELGMLLTG 258
A SF I EEWG LD+SQK LY D E YG++ S+G E++ EL
Sbjct: 224 A-VSF----ILEEWGHLDQSQKSLYRDDRKENYGSITSMGY-----ESRDNMEL------ 267
Query: 259 TGVCRSLRSGNESEG-PPGCPEAQPPQGPGPAAWEGLSGAA---TPAPTV-RPGTPPVPT 313
+ + + +ES P E PQ P A L G PTV + P
Sbjct: 268 --IVKQISDDSESHWVAPEHTERSVPQDPDFAEVSDLKGMVQRWQVNPTVGKSRQNPSQK 325
Query: 314 QPTPAETRLEPAATP--RKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGEST 371
+ A T + P + + + C CG+ F S F+ H R HT + P GE
Sbjct: 326 RDLDAITDISPKQSTHGERGHRCSDCGKFFLQASNFIQHRRIHTG----EKP-FKCGECG 380
Query: 372 EKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRA 431
+ Q V H +R TG + Y C+ CG +F S LV H H+G+R + C++CG+
Sbjct: 381 KSYNQ-RVHLTQH-QRVHTGEKPYKCQVCGKAFRVSSHLVQHHSVHSGERPYGCNECGKN 438
Query: 432 FDWKSQLVIHRKGH 445
F S L+ H K H
Sbjct: 439 FGRHSHLIEHLKRH 452
Score = 75.9 bits (185), Expect = 7e-14
Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 23/129 (17%)
Query: 330 KPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQ--------GEVAF 381
+PY C+ CG+ F + S + H+RTHT+ EKP Q G+ +
Sbjct: 715 QPYQCDICGKAFGYSSDLIQHYRTHTA---------------EKPYQCDICRENVGQCSH 759
Query: 382 PHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIH 441
++ + +S+ C ECG F+ KS L H++ HTG++ C +CG F W L H
Sbjct: 760 TKQHQKIYSSTKSHQCHECGRGFTLKSHLNQHQRIHTGEKPFQCKECGMNFSWSCSLFKH 819
Query: 442 RKGHRPEVP 450
+ H P
Sbjct: 820 LRSHERTDP 828
Score = 68.2 bits (165), Expect = 1e-11
Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 325 AATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHH 384
++T +P+ C +CG+ F + + H R HT + E K V H
Sbjct: 542 SSTGERPHKCNECGKSFIQSAHLIQHQRIHTGEKPFRC------EECGKSYNQRVHLTQH 595
Query: 385 PRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKG 444
+R TG + Y C CG +F +S LV H+ H+G+R C++CG+ F +S L H +
Sbjct: 596 -QRVHTGEKPYTCPLCGKAFRVRSHLVQHQSVHSGERPFKCNECGKGFGRRSHLAGHLRL 654
Query: 445 HRPE 448
H E
Sbjct: 655 HSRE 658
Score = 60.8 bits (146), Expect = 2e-09
Identities = 27/81 (33%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Query: 370 STEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCG 429
S+++ EV + H ++S TG R + C ECG SF + L+ H++ HTG++ C +CG
Sbjct: 526 SSKRMNYSEVPYVH--KKSSTGERPHKCNECGKSFIQSAHLIQHQRIHTGEKPFRCEECG 583
Query: 430 RAFDWKSQLVIHRKGHRPEVP 450
++++ + L H++ H E P
Sbjct: 584 KSYNQRVHLTQHQRVHTGEKP 604
Score = 58.5 bits (140), Expect = 1e-08
Identities = 37/126 (29%), Positives = 52/126 (41%), Gaps = 21/126 (16%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAF----- 381
T KP+ CE+CG+ ++ + H R HT GE P AF
Sbjct: 572 TGEKPFRCEECGKSYNQRVHLTQHQRVHT------------GEKPYTCPLCGKAFRVRSH 619
Query: 382 --PHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLV 439
H S G R + C ECG F +S L H + H+ ++ H C +CG F L+
Sbjct: 620 LVQHQSVHS--GERPFKCNECGKGFGRRSHLAGHLRLHSREKSHQCRECGEIFFQYVSLI 677
Query: 440 IHRKGH 445
H+ H
Sbjct: 678 EHQVLH 683
Score = 55.8 bits (133), Expect = 8e-08
Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 368 GESTEKPPQG---EVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHF 424
G+S + P Q + P++S G R + C +CG F S + HR+ HTG++
Sbjct: 316 GKSRQNPSQKRDLDAITDISPKQSTHGERGHRCSDCGKFFLQASNFIQHRRIHTGEKPFK 375
Query: 425 CSDCGRAFDWKSQLVIHRKGHRPEVP 450
C +CG++++ + L H++ H E P
Sbjct: 376 CGECGKSYNQRVHLTQHQRVHTGEKP 401
Score = 52.8 bits (125), Expect = 6e-07
Identities = 40/159 (25%), Positives = 57/159 (35%), Gaps = 35/159 (22%)
Query: 320 TRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEV 379
T+ + T KPYTC CG+ F +S V H H+ + G G +
Sbjct: 593 TQHQRVHTGEKPYTCPLCGKAFRVRSHLVQHQSVHSGERPFKCNECGKGFGRRSHLAGHL 652
Query: 380 AFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRR----------------- 422
H R +S+ C ECG F L+ H+ H GQ+
Sbjct: 653 RL--HSRE-----KSHQCRECGEIFFQYVSLIEHQVLHMGQKNEKNGICEEAYSWNLTVI 705
Query: 423 -----------HFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
+ C CG+AF + S L+ H + H E P
Sbjct: 706 EDKKIELQEQPYQCDICGKAFGYSSDLIQHYRTHTAEKP 744
Score = 32.3 bits (72), Expect = 0.90
Identities = 11/28 (39%), Positives = 15/28 (53%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTH 354
T KP+ C++CG F W H R+H
Sbjct: 796 TGEKPFQCKECGMNFSWSCSLFKHLRSH 823
>gi|11036642 zinc finger with KRAB and SCAN domains 5 [Homo sapiens]
Length = 839
Score = 196 bits (499), Expect = 3e-50
Identities = 154/434 (35%), Positives = 206/434 (47%), Gaps = 39/434 (8%)
Query: 23 ETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPPEI 82
ET RFR F Y E +GPREAL++LR LCC+WL+PE H+KEQ+LE+LVLEQFL LP E
Sbjct: 47 ETFYQRFRHFQYHEASGPREALSQLRVLCCEWLRPELHTKEQILELLVLEQFLTILPEEF 106
Query: 83 QAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTE---EPLGSPH 139
Q WVR P S EEA A++E +Q + + I A +VLP T + SPH
Sbjct: 107 QPWVREHHPESGEEAVAVIENIQRELEERRQQIVA---CPDVLPRKMATPGAVQESCSPH 163
Query: 140 PSGTVESPGEGPQDTR-IEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGHQEP 198
P P + PQ R +E + V P D QE+ S +Q +
Sbjct: 164 PLTVDTQPEQAPQKPRLLEENALPVLQVPSLPLKDSQELTASLLSTGSQKLVKIEEVADV 223
Query: 199 ASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQPEAQAQSELGMLLTG 258
A SF I EEWG LD+SQK LY D E YG++ S+G E++ EL
Sbjct: 224 A-VSF----ILEEWGHLDQSQKSLYRDDRKENYGSITSMGY-----ESRDNMEL------ 267
Query: 259 TGVCRSLRSGNESEG-PPGCPEAQPPQGPGPAAWEGLSGAA---TPAPTV-RPGTPPVPT 313
+ + + +ES P E PQ P A L G PTV + P
Sbjct: 268 --IVKQISDDSESHWVAPEHTERSVPQDPDFAEVSDLKGMVQRWQVNPTVGKSRQNPSQK 325
Query: 314 QPTPAETRLEPAATP--RKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGEST 371
+ A T + P + + + C CG+ F S F+ H R HT + P GE
Sbjct: 326 RDLDAITDISPKQSTHGERGHRCSDCGKFFLQASNFIQHRRIHTG----EKP-FKCGECG 380
Query: 372 EKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRA 431
+ Q V H +R TG + Y C+ CG +F S LV H H+G+R + C++CG+
Sbjct: 381 KSYNQ-RVHLTQH-QRVHTGEKPYKCQVCGKAFRVSSHLVQHHSVHSGERPYGCNECGKN 438
Query: 432 FDWKSQLVIHRKGH 445
F S L+ H K H
Sbjct: 439 FGRHSHLIEHLKRH 452
Score = 75.9 bits (185), Expect = 7e-14
Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 23/129 (17%)
Query: 330 KPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQ--------GEVAF 381
+PY C+ CG+ F + S + H+RTHT+ EKP Q G+ +
Sbjct: 715 QPYQCDICGKAFGYSSDLIQHYRTHTA---------------EKPYQCDICRENVGQCSH 759
Query: 382 PHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIH 441
++ + +S+ C ECG F+ KS L H++ HTG++ C +CG F W L H
Sbjct: 760 TKQHQKIYSSTKSHQCHECGRGFTLKSHLNQHQRIHTGEKPFQCKECGMNFSWSCSLFKH 819
Query: 442 RKGHRPEVP 450
+ H P
Sbjct: 820 LRSHERTDP 828
Score = 68.2 bits (165), Expect = 1e-11
Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 325 AATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHH 384
++T +P+ C +CG+ F + + H R HT + E K V H
Sbjct: 542 SSTGERPHKCNECGKSFIQSAHLIQHQRIHTGEKPFRC------EECGKSYNQRVHLTQH 595
Query: 385 PRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKG 444
+R TG + Y C CG +F +S LV H+ H+G+R C++CG+ F +S L H +
Sbjct: 596 -QRVHTGEKPYTCPLCGKAFRVRSHLVQHQSVHSGERPFKCNECGKGFGRRSHLAGHLRL 654
Query: 445 HRPE 448
H E
Sbjct: 655 HSRE 658
Score = 60.8 bits (146), Expect = 2e-09
Identities = 27/81 (33%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Query: 370 STEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCG 429
S+++ EV + H ++S TG R + C ECG SF + L+ H++ HTG++ C +CG
Sbjct: 526 SSKRMNYSEVPYVH--KKSSTGERPHKCNECGKSFIQSAHLIQHQRIHTGEKPFRCEECG 583
Query: 430 RAFDWKSQLVIHRKGHRPEVP 450
++++ + L H++ H E P
Sbjct: 584 KSYNQRVHLTQHQRVHTGEKP 604
Score = 58.5 bits (140), Expect = 1e-08
Identities = 37/126 (29%), Positives = 52/126 (41%), Gaps = 21/126 (16%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAF----- 381
T KP+ CE+CG+ ++ + H R HT GE P AF
Sbjct: 572 TGEKPFRCEECGKSYNQRVHLTQHQRVHT------------GEKPYTCPLCGKAFRVRSH 619
Query: 382 --PHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLV 439
H S G R + C ECG F +S L H + H+ ++ H C +CG F L+
Sbjct: 620 LVQHQSVHS--GERPFKCNECGKGFGRRSHLAGHLRLHSREKSHQCRECGEIFFQYVSLI 677
Query: 440 IHRKGH 445
H+ H
Sbjct: 678 EHQVLH 683
Score = 55.8 bits (133), Expect = 8e-08
Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 368 GESTEKPPQG---EVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHF 424
G+S + P Q + P++S G R + C +CG F S + HR+ HTG++
Sbjct: 316 GKSRQNPSQKRDLDAITDISPKQSTHGERGHRCSDCGKFFLQASNFIQHRRIHTGEKPFK 375
Query: 425 CSDCGRAFDWKSQLVIHRKGHRPEVP 450
C +CG++++ + L H++ H E P
Sbjct: 376 CGECGKSYNQRVHLTQHQRVHTGEKP 401
Score = 52.8 bits (125), Expect = 6e-07
Identities = 40/159 (25%), Positives = 57/159 (35%), Gaps = 35/159 (22%)
Query: 320 TRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEV 379
T+ + T KPYTC CG+ F +S V H H+ + G G +
Sbjct: 593 TQHQRVHTGEKPYTCPLCGKAFRVRSHLVQHQSVHSGERPFKCNECGKGFGRRSHLAGHL 652
Query: 380 AFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRR----------------- 422
H R +S+ C ECG F L+ H+ H GQ+
Sbjct: 653 RL--HSRE-----KSHQCRECGEIFFQYVSLIEHQVLHMGQKNEKNGICEEAYSWNLTVI 705
Query: 423 -----------HFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
+ C CG+AF + S L+ H + H E P
Sbjct: 706 EDKKIELQEQPYQCDICGKAFGYSSDLIQHYRTHTAEKP 744
Score = 32.3 bits (72), Expect = 0.90
Identities = 11/28 (39%), Positives = 15/28 (53%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTH 354
T KP+ C++CG F W H R+H
Sbjct: 796 TGEKPFQCKECGMNFSWSCSLFKHLRSH 823
>gi|57863253 zinc finger protein 500 [Homo sapiens]
Length = 480
Score = 196 bits (498), Expect = 4e-50
Identities = 155/441 (35%), Positives = 199/441 (45%), Gaps = 50/441 (11%)
Query: 16 ETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFL 75
ET PET R FR FCYQEVAGPREAL+RL ELCC+WL+PE +KEQ+LE+LVLEQFL
Sbjct: 40 ETEDPSPETFRQLFRLFCYQEVAGPREALSRLWELCCRWLRPELRTKEQILELLVLEQFL 99
Query: 76 GTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEPL 135
LP EIQA VR Q+P S EEA LVEGLQ P + H + L + + +
Sbjct: 100 TVLPGEIQARVREQQPESGEEAVVLVEGLQRKPRK-------HRQRGSELLSDDEVPLGI 152
Query: 136 GSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGH 195
G E+ P+D +E + S ++P P L + H
Sbjct: 153 GGQFLKHQAEAQ---PEDLSLEEEARFS---SQQPPAQLSHRPQRGPLLWPERGPPAPRH 206
Query: 196 QEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQPEAQAQSELGML 255
QE AS S W + + ++ V++ L +P ++
Sbjct: 207 QEMASAS----PFLSAWSQVPVNLED-------------VAVYLSGEEPRCMDPAQRDAP 249
Query: 256 LTGTGVCRSLRSGNES-EGPPGCPE-----AQPPQGPGPAAWEGLSGAATPAPTVRPGTP 309
L G L G + E P E + QGPG L G PAP P
Sbjct: 250 LENEGPGIQLEDGGDGREDAPLRMEWYRVLSARCQGPG----HPLPG-QRPAPVRGLVRP 304
Query: 310 PVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGE 369
P P R A KPYTC +CG+GF S H RTHT + G
Sbjct: 305 DQPRGGPPPGRRASHGAD--KPYTCPECGKGFSKTSHLTKHQRTHTGERPYKCLVCGKGF 362
Query: 370 STEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCG 429
S F H +R TG + YPC ECG FS S LVIHR++H+G+R + C+ CG
Sbjct: 363 SDRS------NFSTH-QRVHTGEKPYPCPECGKRFSQSSSLVIHRRTHSGERPYACTQCG 415
Query: 430 RAFDWKSQLVIHRKGHRPEVP 450
+ F+ S HR+ H E P
Sbjct: 416 KRFNNSSHFSAHRRTHTGEKP 436
>gi|31543980 zinc finger protein 263 [Homo sapiens]
Length = 683
Score = 187 bits (475), Expect = 2e-47
Identities = 171/513 (33%), Positives = 226/513 (44%), Gaps = 95/513 (18%)
Query: 10 LPVMDPETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEML 69
LP DP + PE + LRFR F +QE AGPREAL+RL+ELC WL+PE +KEQ+LE+L
Sbjct: 28 LPPPDPGPS---PEASHLRFRRFRFQEAAGPREALSRLQELCHGWLRPEMRTKEQILELL 84
Query: 70 VLEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAH-----VLKQEV 124
VLEQFL LP EIQ+ V+ P S EEA LVE +Q + G+L +T H VL +E
Sbjct: 85 VLEQFLTILPQEIQSRVQELHPESGEEAVTLVEDMQRELGRLRQQVTNHGRGTEVLLEEP 144
Query: 125 LPAAQKTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPL 184
LP E P P T SPG Q+ L S + +P +E A S+P L
Sbjct: 145 LPLETARESPSFKLEPMETERSPGPRLQEL-------LGPSPQRDPQAV-KERALSAPWL 196
Query: 185 AAQSPEGNH------GHQEPASTSFHPPRI-QEEWGLLDRSQKELYWDAMLEKYGTVVSL 237
+ PEGN G Q P S I QEEWG D S++ L D + E Y V SL
Sbjct: 197 SLFPPEGNMEDKEMTGPQLPESLEDVAMYISQEEWGHQDPSKRALSRDTVQESYENVDSL 256
Query: 238 GLPPHQPEAQAQSELGMLLTGTGVCRSLRSGNESEGPPGCPEAQPPQGPGPAA--WEGLS 295
H P + + GT V + + + S C E P+GP P +E L
Sbjct: 257 --ESHIPSQE--------VPGTQVGQGGKLWDPSV--QSCKEGLSPRGPAPGEEKFENLE 304
Query: 296 GAATP-APTVRP-------GTPPVPTQPT--------------PAETRLEPAAT------ 327
G + + + P VP P P E +E A
Sbjct: 305 GVPSVCSENIHPQVLLPDQARGEVPWSPELGRPHDRSQGDWAPPPEGGMEQALAGASSGR 364
Query: 328 ---------PRKPYTCEQCGRGFDWKSVFVIHHRTHTSGP---GVQSPGLATGE----ST 371
P+K + C CG+ F S + H R H + GV + G S
Sbjct: 365 ELGRPKELQPKKLHLCPLCGKNFSNNSNLIRHQRIHAAERLCMGVDCTEIFGGNPRFLSL 424
Query: 372 EKPPQGEVAFP------------HHPR--RSLTGPRSYPCEECGCSFSWKSQLVIHRKSH 417
+ GE A H R R+ TG + Y C CG FS S L H+++H
Sbjct: 425 HRAHLGEEAHKCLECGKCFSQNTHLTRHQRTHTGEKPYQCNICGKCFSCNSNLHRHQRTH 484
Query: 418 TGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
TG++ + C +CG F S L+ H++ H E P
Sbjct: 485 TGEKPYKCPECGEIFAHSSNLLRHQRIHTGERP 517
Score = 74.7 bits (182), Expect = 2e-13
Identities = 47/134 (35%), Positives = 60/134 (44%), Gaps = 17/134 (12%)
Query: 320 TRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEV 379
TR + T KPY C CG+ F S H RTHT GE K P+
Sbjct: 450 TRHQRTHTGEKPYQCNICGKCFSCNSNLHRHQRTHT------------GEKPYKCPECGE 497
Query: 380 AFPHHP-----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDW 434
F H +R TG R Y C ECG SFS S LVIH ++H +R + S+CG A
Sbjct: 498 IFAHSSNLLRHQRIHTGERPYKCPECGKSFSRSSHLVIHERTHERERLYPFSECGEAVSD 557
Query: 435 KSQLVIHRKGHRPE 448
+ + + H+ E
Sbjct: 558 STPFLTNHGAHKAE 571
Score = 72.4 bits (176), Expect = 8e-13
Identities = 41/126 (32%), Positives = 55/126 (43%), Gaps = 35/126 (27%)
Query: 320 TRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEV 379
TR + T KPY C CG F +S + H R HT EKP
Sbjct: 591 TRHQRTHTGEKPYKCTLCGENFSHRSNLIRHQRIHTG---------------EKP----- 630
Query: 380 AFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLV 439
Y C ECG SFS S + H ++HTG+R + CS+CG +F S+L+
Sbjct: 631 ---------------YTCHECGDSFSHSSNRIRHLRTHTGERPYKCSECGESFSRSSRLM 675
Query: 440 IHRKGH 445
H++ H
Sbjct: 676 SHQRTH 681
Score = 71.6 bits (174), Expect = 1e-12
Identities = 45/148 (30%), Positives = 66/148 (44%), Gaps = 26/148 (17%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHT----------------SGPGVQSPGLATGES 370
T +PY C +CG+ F S VIH RTH S P + + G E
Sbjct: 513 TGERPYKCPECGKSFSRSSHLVIHERTHERERLYPFSECGEAVSDSTPFLTNHGAHKAEK 572
Query: 371 T--------EKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRR 422
+ QG H +R+ TG + Y C CG +FS +S L+ H++ HTG++
Sbjct: 573 KLFECLTCGKSFRQGMHLTRH--QRTHTGEKPYKCTLCGENFSHRSNLIRHQRIHTGEKP 630
Query: 423 HFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
+ C +CG +F S + H + H E P
Sbjct: 631 YTCHECGDSFSHSSNRIRHLRTHTGERP 658
>gi|171906553 zinc finger with KRAB and SCAN domains 3 [Homo
sapiens]
Length = 538
Score = 182 bits (462), Expect = 5e-46
Identities = 148/446 (33%), Positives = 195/446 (43%), Gaps = 63/446 (14%)
Query: 23 ETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPPEI 82
E +R RFRGF Y E AGPREAL+RLRELC QWLQPE HSKEQ+LE+LVLEQFL LP +
Sbjct: 43 EGSRERFRGFRYPEAAGPREALSRLRELCRQWLQPEMHSKEQILELLVLEQFLTILPGNL 102
Query: 83 QAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEPLGSPHPSG 142
Q+WVR Q P S EE L+E L+ + ++ QE+L P S
Sbjct: 103 QSWVREQHPESGEEVVVLLEYLERQLDEPAPQVSGVDQGQELLCCKMALLTPAPGSQSSQ 162
Query: 143 --------TVESPGEGP-QDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNH 193
ES G P QD ++ V E V + P S L
Sbjct: 163 FQLMKALLKHESVGSQPLQDRVLQVPVLAHGGCCREDKVVASRLTPESQGLL-------- 214
Query: 194 GHQEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLG---------LPPHQP 244
E + + P EW D SQ L D E +G++VSLG LPP
Sbjct: 215 -KVEDVALTLTP-----EWTQQDSSQGNLCRDEKQENHGSLVSLGDEKQTKSRDLPP--A 266
Query: 245 EAQAQSELGMLLTGTGVCRSLRSGNESEGPPGCPEAQPPQGPGPAAWEGLSGAATPAPTV 304
E + E G + S + P C EA +G + +G
Sbjct: 267 EELPEKEHGKI--------SCHLREDIAQIPTCAEAGEQEGRLQRKQKNATGGRRHI-CH 317
Query: 305 RPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPG 364
G + R+ T KPY CE+CG+ F S VIH R H
Sbjct: 318 ECGKSFAQSSGLSKHRRIH---TGEKPYECEECGKAFIGSSALVIHQRVH---------- 364
Query: 365 LATGESTEKPPQGEVAFPHHP-----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTG 419
TGE + + AF H +R+ TG + Y C++CG +FS L+ H + HTG
Sbjct: 365 --TGEKPYECEECGKAFSHSSDLIKHQRTHTGEKPYECDDCGKTFSQSCSLLEHHRIHTG 422
Query: 420 QRRHFCSDCGRAFDWKSQLVIHRKGH 445
++ + CS CG+AF S L+ H++ H
Sbjct: 423 EKPYQCSMCGKAFRRSSHLLRHQRIH 448
Score = 79.0 bits (193), Expect = 8e-15
Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 9/119 (7%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T KPY C CG+ F S + H R HT VQ P GE+ + + ++
Sbjct: 421 TGEKPYQCSMCGKAFRRSSHLLRHQRIHTGDKNVQEP--EQGEAWKSRMESQL------- 471
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGH 445
++ P SY C EC SF+ + L+ H+K HTG++ + C+ CG+ F S LV H++ H
Sbjct: 472 ENVETPMSYKCNECERSFTQNTGLIEHQKIHTGEKPYQCNACGKGFTRISYLVQHQRSH 530
Score = 40.0 bits (92), Expect = 0.004
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 3/54 (5%)
Query: 397 CEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
C E G + +L +K+ TG RRH C +CG++F S L HR+ H E P
Sbjct: 291 CAEAG---EQEGRLQRKQKNATGGRRHICHECGKSFAQSSGLSKHRRIHTGEKP 341
>gi|55769564 zinc finger protein 36 [Homo sapiens]
Length = 563
Score = 182 bits (462), Expect = 5e-46
Identities = 149/492 (30%), Positives = 217/492 (44%), Gaps = 78/492 (15%)
Query: 16 ETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFL 75
+T +PE R RFR FCYQ GPREAL+RL+ELC QWL+PE ++KEQ+LE+LVLEQFL
Sbjct: 46 DTPPPDPEIFRQRFRRFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFL 105
Query: 76 GTLPPEIQAWVRGQRPGSPEEAAALVEGLQHD------PGQLLGWITAHVLKQEVLPAAQ 129
LP E+Q W++ RP S EEA L+E L+ D PGQ+ G +L + ++P
Sbjct: 106 SILPKELQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHG---PEMLARGMVPLDP 162
Query: 130 KTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDG--QEVAPSSPPLAAQ 187
E H T + R+ S L + P +G ++ A +S A
Sbjct: 163 VQESSSFDLHHEATQSHFKHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTAD 222
Query: 188 SPEGNHGHQEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLG----LPPHQ 243
S S I EEWG + +++ L D E YG+ G +
Sbjct: 223 SQAMVKIEDMAVSL------ILEEWGCQNLARRNLSRDNRQENYGSAFPQGGENRNENEE 276
Query: 244 PEAQAQSELGMLLTGTGVCRSLRSGNE---SEGPPGCPEAQPPQ--------GPGPAAWE 292
++A++ G RS + E EG G + + P+ GPA +
Sbjct: 277 STSKAETSEDSASRGETTGRSQKEFGEKRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGK 336
Query: 293 G---LSGAATP--------------APTVRPGTPPVPTQP------------TPAETRLE 323
++G P + P P T+ + + R +
Sbjct: 337 DKKTITGERGPREKGKGLGRSFSLSSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHK 396
Query: 324 PAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPH 383
T KPY C +CG+ F S V+H R H TGE + + AF H
Sbjct: 397 IIHTGEKPYECSECGKAFSLNSNLVLHQRIH------------TGEKPHECNECGKAFSH 444
Query: 384 HP-----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQL 438
+R +G + Y C ECG +FS S L H++ HTG++ + CS+CG+AF+ S L
Sbjct: 445 SSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYL 504
Query: 439 VIHRKGHRPEVP 450
++HR+ H E P
Sbjct: 505 ILHRRIHTREKP 516
Score = 47.8 bits (112), Expect = 2e-05
Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 17/97 (17%)
Query: 330 KPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHP---- 385
KPY C +CG+ F S H R HT GE + + AF +
Sbjct: 459 KPYECNECGKAFSQSSDLTKHQRIHT------------GEKPYECSECGKAFNRNSYLIL 506
Query: 386 -RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQR 421
RR T + Y C +CG +F+ S L +H + H +R
Sbjct: 507 HRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARER 543
>gi|64368880 zinc finger and SCAN domain containing 25 [Homo
sapiens]
Length = 544
Score = 181 bits (458), Expect = 2e-45
Identities = 149/460 (32%), Positives = 207/460 (45%), Gaps = 70/460 (15%)
Query: 22 PETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPPE 81
PET RLRFR F YQE AGP+EAL L+ELC +WL+PE H+KEQ+LE+LVLEQFL LP E
Sbjct: 38 PETFRLRFRQFRYQEAAGPQEALRELQELCRRWLRPELHTKEQILELLVLEQFLTILPRE 97
Query: 82 IQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEP-----LG 136
AW+R P S + AA+VE L T L+ + +P ++ E+ G
Sbjct: 98 FYAWIREHGPESGKALAAMVEDL-----------TERALEAKAVPCHRQGEQEETALCRG 146
Query: 137 SPHPS---GTVE-------SPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAP---SSPP 183
+ P G VE PGEG Q QLS +E ++ P + P
Sbjct: 147 AWEPGIQLGPVEVKPEWGMPPGEGVQGPDPGTEEQLSQDPGDETRAFQEQALPVLQAGPG 206
Query: 184 LAAQSPEGNH---GHQEPASTSFHPPR------IQEEWGLLDRSQKELYWDAMLEKYGTV 234
L A +P G S P + +EEW + +Q + + + +E
Sbjct: 207 LPAVNPRDQEMAAGFFTAGSQGLGPFKDMALAFPEEEWRHVTPAQIDCFGE-YVEPQDCR 265
Query: 235 VSLGLPPHQPEAQAQSE--LGMLLTGTGVCRSLRSGNESEGPPGCPEA--QPPQGPGPAA 290
VS G + EA+ E G L+ T S R G S PG Q P GP +A
Sbjct: 266 VSPGGGSKEKEAKPPQEDLKGALVALT----SERFGEASLQGPGLGRVCEQEPGGPAGSA 321
Query: 291 WEGLSGAATPAPTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIH 350
PG PP P ++ ++ KP+ C +CG+GF S V H
Sbjct: 322 ---------------PGLPPPQHGAIPLPDEVKTHSSFWKPFQCPECGKGFSRSSNLVRH 366
Query: 351 HRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQL 410
RTH + E + E H +R+ G R Y C EC +FS + L
Sbjct: 367 QRTH------EEKSYGCVECGKGFTLREYLMKH--QRTHLGKRPYVCSECWKTFSQRHHL 418
Query: 411 VIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
+H++SHTG++ + C DC ++F + L +HR+ H E P
Sbjct: 419 EVHQRSHTGEKPYKCGDCWKSFSRRQHLQVHRRTHTGEKP 458
Score = 73.2 bits (178), Expect = 5e-13
Identities = 44/123 (35%), Positives = 63/123 (51%), Gaps = 9/123 (7%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T KPY C C + F + +H RTHT G + G+S + V R
Sbjct: 426 TGEKPYKCGDCWKSFSRRQHLQVHRRTHT---GEKPYTCECGKSFSRNANLAVH-----R 477
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRK-GH 445
R+ TG + Y C+ CG FS +LV H++ HTG++ + C CGR+F+ +S L H+K H
Sbjct: 478 RAHTGEKPYGCQVCGKRFSKGERLVRHQRIHTGEKPYHCPACGRSFNQRSILNRHQKTQH 537
Query: 446 RPE 448
R E
Sbjct: 538 RQE 540
Score = 35.4 bits (80), Expect = 0.11
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 35/96 (36%)
Query: 325 AATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHH 384
A T KPY C+ CG+ F V H R H
Sbjct: 479 AHTGEKPYGCQVCGKRFSKGERLVRHQRIH------------------------------ 508
Query: 385 PRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQ 420
TG + Y C CG SF+ +S L H+K+ Q
Sbjct: 509 -----TGEKPYHCPACGRSFNQRSILNRHQKTQHRQ 539
>gi|56699475 zinc finger protein 202 [Homo sapiens]
Length = 648
Score = 180 bits (456), Expect = 3e-45
Identities = 152/476 (31%), Positives = 210/476 (44%), Gaps = 94/476 (19%)
Query: 15 PETTLEEP----ETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLV 70
PE+ L+ ET+ FR F YQE A PREAL RLRELC QWL+PE +KEQ+LE+LV
Sbjct: 31 PESVLQRDDPVLETSHQNFRRFRYQEAASPREALIRLRELCHQWLRPERRTKEQILELLV 90
Query: 71 LEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLP---- 126
LEQFL LP E+Q+WVRGQRP S EEA LVEGLQ P + W+T HV QEVL
Sbjct: 91 LEQFLTVLPGELQSWVRGQRPESGEEAVTLVEGLQKQPRRPRRWVTVHVHGQEVLSEETV 150
Query: 127 ---AAQKTEEPLGSPHPSGTVE-SPGEGPQDTRIEGSVQLSCSVKEEPNV--DGQEVAPS 180
++ L P S T E SP E Q + + +EE + + P
Sbjct: 151 HLGVEPESPNELQDPVQSSTPEQSPEETTQSPDLGAPAEQRPHQEEELQTLQESEVPVPE 210
Query: 181 SPPLAAQSPEGNHGHQEPASTSFHPPRI----------QEEWGLLDRSQKELYWDAMLEK 230
P L A+ G+ T+ + Q++W LD +QKE Y + +LE+
Sbjct: 211 DPDLPAERSSGD-SEMVALLTALSQGLVTFKDVAVCFSQDQWSDLDPTQKEFYGEYVLEE 269
Query: 231 -YGTVVSLGLPPHQPEAQAQSELGMLLTGTGVCRSLRSGNESEGPPGCPEAQPPQGPGPA 289
G VVSL P +P+ +Q E P P+ Q PQ
Sbjct: 270 DCGIVVSLSFPIPRPDEISQVR--------------------EEEPWVPDIQEPQ----- 304
Query: 290 AWEGLSGAATPAPTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGF-------- 341
T P + T T ++ E ++ + E R
Sbjct: 305 --------ETQEPEILSFT------YTGDRSKDEEECLEQEDLSLEDIHRPVLGEPEIHQ 350
Query: 342 --DWKSVFV-----IHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRS 394
DW+ VF ++ R + + + E+T P HP L G R
Sbjct: 351 TPDWEIVFEDNPGRLNERRFGTNISQVNSFVNLRETT----------PVHP---LLG-RH 396
Query: 395 YPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
+ C CG SF+ S LV H ++HTG++ + C +CG+++ S L H+K H+ P
Sbjct: 397 HDCSVCGKSFTCNSHLVRHLRTHTGEKPYKCMECGKSYTRSSHLARHQKVHKMNAP 452
Score = 80.9 bits (198), Expect = 2e-15
Identities = 47/134 (35%), Positives = 64/134 (47%), Gaps = 11/134 (8%)
Query: 314 QPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLAT--GEST 371
+ T T+ E + KPY C+ CG+ F W S V H RTHT + P T G+S
Sbjct: 463 EETSPVTQAERTPSVEKPYRCDDCGKHFRWTSDLVRHQRTHTG----EKPFFCTICGKSF 518
Query: 372 EKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRA 431
Q V H +R G + Y C ECG FS + + HRK+H + + CS+CGR
Sbjct: 519 S---QKSVLTTH--QRIHLGGKPYLCGECGEDFSEHRRYLAHRKTHAAEELYLCSECGRC 573
Query: 432 FDWKSQLVIHRKGH 445
F + H +GH
Sbjct: 574 FTHSAAFAKHLRGH 587
Score = 76.3 bits (186), Expect = 5e-14
Identities = 39/120 (32%), Positives = 59/120 (49%), Gaps = 9/120 (7%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSP-GLATGESTEKPPQGEVAFPHHP 385
T KPY C +CG+ + S H + H + P E T Q E
Sbjct: 420 TGEKPYKCMECGKSYTRSSHLARHQKVHKMNAPYKYPLNRKNLEETSPVTQAE------- 472
Query: 386 RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGH 445
R+ + + Y C++CG F W S LV H+++HTG++ FC+ CG++F KS L H++ H
Sbjct: 473 -RTPSVEKPYRCDDCGKHFRWTSDLVRHQRTHTGEKPFFCTICGKSFSQKSVLTTHQRIH 531
Score = 63.9 bits (154), Expect = 3e-10
Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 7/116 (6%)
Query: 330 KPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSL 389
KPY C +CG F ++ H +TH + L + AF H R
Sbjct: 535 KPYLCGECGEDFSEHRRYLAHRKTHAAEE------LYLCSECGRCFTHSAAFAKH-LRGH 587
Query: 390 TGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGH 445
R C ECG SFS + LV H+++HTG++ C CG++F L+ H++ H
Sbjct: 588 ASVRPCRCNECGKSFSRRDHLVRHQRTHTGEKPFTCPTCGKSFSRGYHLIRHQRTH 643
Score = 40.0 bits (92), Expect = 0.004
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 7/87 (8%)
Query: 332 YTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSLTG 391
Y C +CGR F + F H R H S + E + + + H +R+ TG
Sbjct: 565 YLCSECGRCFTHSAAFAKHLRGHASVRPCRC-----NECGKSFSRRDHLVRH--QRTHTG 617
Query: 392 PRSYPCEECGCSFSWKSQLVIHRKSHT 418
+ + C CG SFS L+ H+++H+
Sbjct: 618 EKPFTCPTCGKSFSRGYHLIRHQRTHS 644
Score = 31.6 bits (70), Expect = 1.5
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHT 355
T KP+TC CG+ F + H RTH+
Sbjct: 616 TGEKPFTCPTCGKSFSRGYHLIRHQRTHS 644
>gi|17738285 zinc finger with KRAB and SCAN domains 4 [Homo sapiens]
Length = 545
Score = 174 bits (440), Expect = 2e-43
Identities = 144/446 (32%), Positives = 188/446 (42%), Gaps = 60/446 (13%)
Query: 12 VMDPETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVL 71
V P + PE +R RFRGF Y E AGPREAL+RLRELC QWLQPE HSKEQ+LE+LVL
Sbjct: 39 VRAPCSPARGPERSRQRFRGFRYPEAAGPREALSRLRELCGQWLQPEMHSKEQILELLVL 98
Query: 72 EQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKT 131
EQFL LP +Q+WVR Q P S EE L+E L+ + + QE+L
Sbjct: 99 EQFLTILPGNLQSWVREQHPESGEEVVVLLEYLERQLDEPAPQVPVGDQGQELLCCKMAL 158
Query: 132 EEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEG 191
S P + GS L V + P + +A++ G
Sbjct: 159 LTQTQGSQSSQC--QPMKALFKHESLGSQPLHDRVLQVPGLAQGGCCREDAMVASRLTPG 216
Query: 192 NHG--HQEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQPEAQAQ 249
+ G E + + P W LD SQ LY D E + ++VSLG E Q +
Sbjct: 217 SQGLLKMEDVALTLTP-----GWTQLDSSQVNLYRDEKQENHSSLVSLG-----GEIQTK 266
Query: 250 SELGMLLTGTGVCRSLRSGNESEGPPGCPEAQPPQGPGPAAWEGLSGAATPAPTVRPGTP 309
S R L PP P G +R
Sbjct: 267 S------------RDL----------------PPVKKLPEKEHG------KICHLREDIA 292
Query: 310 PVPTQPTPAE-----TRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPG 364
+PT E R + A + + C +CG+ F S H R HT +
Sbjct: 293 QIPTHAEAGEQEGRLQRKQKNAIGSRRHYCHECGKSFAQSSGLTKHRRIHTGEKPYEC-- 350
Query: 365 LATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHF 424
E K G A H +R TG + Y CEECG FS S L+ H+++HTG++ +
Sbjct: 351 ----EDCGKTFIGSSALVIH-QRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYE 405
Query: 425 CSDCGRAFDWKSQLVIHRKGHRPEVP 450
C DCG+ F L+ H K H E P
Sbjct: 406 CDDCGKTFSQSCSLLEHHKIHTGEKP 431
Score = 74.7 bits (182), Expect = 2e-13
Identities = 43/119 (36%), Positives = 58/119 (48%), Gaps = 8/119 (6%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T KPY C CG+ F S + H R H VQ+P GES E + E +
Sbjct: 427 TGEKPYQCNMCGKAFRRNSHLLRHQRIH-GDKNVQNP--EHGESWESQGRTESQW----- 478
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGH 445
+ P SY C EC SF+ L+ H+K HTG++ + C CG+ F S LV H++ H
Sbjct: 479 ENTEAPVSYKCNECERSFTRNRSLIEHQKIHTGEKPYQCDTCGKGFTRTSYLVQHQRSH 537
>gi|224493912 zinc finger and SCAN domain containing 18 isoform 3
[Homo sapiens]
Length = 510
Score = 172 bits (435), Expect = 7e-43
Identities = 146/458 (31%), Positives = 211/458 (46%), Gaps = 45/458 (9%)
Query: 11 PVMDPETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLV 70
P PE T + E +RLRFR F YQE AGP + LARL ELC QWL PEA SKEQMLE+LV
Sbjct: 34 PETIPERTPADLEFSRLRFREFVYQEAAGPHQTLARLHELCRQWLMPEARSKEQMLELLV 93
Query: 71 LEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQ---HDPGQLLGWI--TAHVLKQEVL 125
LEQFLG LP +++ WV Q P S ++AA+LVEGL +PG LLG ++ +L V
Sbjct: 94 LEQFLGILPDKVRPWVVAQYPESCKKAASLVEGLADVLEEPGMLLGSPAGSSSILSDGVY 153
Query: 126 PAAQKTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLA 185
++ +PL P G + SP + I + + ++ + V
Sbjct: 154 ---ERHMDPLLLP---GELASPSQALGAGEIPAPSETPWLSPDPLFLEQRRVR------E 201
Query: 186 AQSPEGNHGHQEPASTSF-HPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQP 244
A++ E + E SF P+ EWG LD +++ L+ Y ++ G QP
Sbjct: 202 AKTEEDGPANTEQKLKSFPEDPQHLGEWGHLDPAEEN------LKSYRKLLLWGYQLSQP 255
Query: 245 EAQAQ--SELGMLLTGTGVCRSLRSGNESEGPPGC-----------PEAQPPQGPGPAAW 291
+A ++ +E L+ SL G + GC PE PG A
Sbjct: 256 DAASRLDTEELRLVERDPQGSSLPEGGRRQESAGCACEEAAPAGVLPELPTEAPPGDALA 315
Query: 292 EGLSGAATPAPTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHH 351
+ SG T +PG P P P AE+ + A ++ +Q D + +
Sbjct: 316 DPPSG-TTEEEEEQPGKAPDPQDPQDAES--DSATGSQRQSVIQQPAP--DRGTAKLGTK 370
Query: 352 RTH-TSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQL 410
R H G G G+++ + G+ P L+ + Y C ECG +F+W S L
Sbjct: 371 RPHPEDGDGQSLEGVSSSGDSAGLEAGQGPGADEP--GLSRGKPYACGECGEAFAWLSHL 428
Query: 411 VIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPE 448
+ H SH G++R+ C C + F + L H+K H E
Sbjct: 429 MEHHSSHGGRKRYACQGCWKTFHFSLALAEHQKTHEKE 466
>gi|226371704 zinc finger and SCAN domain containing 18 isoform 3
[Homo sapiens]
Length = 510
Score = 172 bits (435), Expect = 7e-43
Identities = 146/458 (31%), Positives = 211/458 (46%), Gaps = 45/458 (9%)
Query: 11 PVMDPETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLV 70
P PE T + E +RLRFR F YQE AGP + LARL ELC QWL PEA SKEQMLE+LV
Sbjct: 34 PETIPERTPADLEFSRLRFREFVYQEAAGPHQTLARLHELCRQWLMPEARSKEQMLELLV 93
Query: 71 LEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQ---HDPGQLLGWI--TAHVLKQEVL 125
LEQFLG LP +++ WV Q P S ++AA+LVEGL +PG LLG ++ +L V
Sbjct: 94 LEQFLGILPDKVRPWVVAQYPESCKKAASLVEGLADVLEEPGMLLGSPAGSSSILSDGVY 153
Query: 126 PAAQKTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLA 185
++ +PL P G + SP + I + + ++ + V
Sbjct: 154 ---ERHMDPLLLP---GELASPSQALGAGEIPAPSETPWLSPDPLFLEQRRVR------E 201
Query: 186 AQSPEGNHGHQEPASTSF-HPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQP 244
A++ E + E SF P+ EWG LD +++ L+ Y ++ G QP
Sbjct: 202 AKTEEDGPANTEQKLKSFPEDPQHLGEWGHLDPAEEN------LKSYRKLLLWGYQLSQP 255
Query: 245 EAQAQ--SELGMLLTGTGVCRSLRSGNESEGPPGC-----------PEAQPPQGPGPAAW 291
+A ++ +E L+ SL G + GC PE PG A
Sbjct: 256 DAASRLDTEELRLVERDPQGSSLPEGGRRQESAGCACEEAAPAGVLPELPTEAPPGDALA 315
Query: 292 EGLSGAATPAPTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHH 351
+ SG T +PG P P P AE+ + A ++ +Q D + +
Sbjct: 316 DPPSG-TTEEEEEQPGKAPDPQDPQDAES--DSATGSQRQSVIQQPAP--DRGTAKLGTK 370
Query: 352 RTH-TSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQL 410
R H G G G+++ + G+ P L+ + Y C ECG +F+W S L
Sbjct: 371 RPHPEDGDGQSLEGVSSSGDSAGLEAGQGPGADEP--GLSRGKPYACGECGEAFAWLSHL 428
Query: 411 VIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPE 448
+ H SH G++R+ C C + F + L H+K H E
Sbjct: 429 MEHHSSHGGRKRYACQGCWKTFHFSLALAEHQKTHEKE 466
>gi|224493905 zinc finger and SCAN domain containing 18 isoform 1
[Homo sapiens]
Length = 566
Score = 172 bits (435), Expect = 7e-43
Identities = 146/458 (31%), Positives = 211/458 (46%), Gaps = 45/458 (9%)
Query: 11 PVMDPETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLV 70
P PE T + E +RLRFR F YQE AGP + LARL ELC QWL PEA SKEQMLE+LV
Sbjct: 90 PETIPERTPADLEFSRLRFREFVYQEAAGPHQTLARLHELCRQWLMPEARSKEQMLELLV 149
Query: 71 LEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQ---HDPGQLLGWI--TAHVLKQEVL 125
LEQFLG LP +++ WV Q P S ++AA+LVEGL +PG LLG ++ +L V
Sbjct: 150 LEQFLGILPDKVRPWVVAQYPESCKKAASLVEGLADVLEEPGMLLGSPAGSSSILSDGVY 209
Query: 126 PAAQKTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLA 185
++ +PL P G + SP + I + + ++ + V
Sbjct: 210 ---ERHMDPLLLP---GELASPSQALGAGEIPAPSETPWLSPDPLFLEQRRVR------E 257
Query: 186 AQSPEGNHGHQEPASTSF-HPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQP 244
A++ E + E SF P+ EWG LD +++ L+ Y ++ G QP
Sbjct: 258 AKTEEDGPANTEQKLKSFPEDPQHLGEWGHLDPAEEN------LKSYRKLLLWGYQLSQP 311
Query: 245 EAQAQ--SELGMLLTGTGVCRSLRSGNESEGPPGC-----------PEAQPPQGPGPAAW 291
+A ++ +E L+ SL G + GC PE PG A
Sbjct: 312 DAASRLDTEELRLVERDPQGSSLPEGGRRQESAGCACEEAAPAGVLPELPTEAPPGDALA 371
Query: 292 EGLSGAATPAPTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHH 351
+ SG T +PG P P P AE+ + A ++ +Q D + +
Sbjct: 372 DPPSG-TTEEEEEQPGKAPDPQDPQDAES--DSATGSQRQSVIQQPAP--DRGTAKLGTK 426
Query: 352 RTH-TSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQL 410
R H G G G+++ + G+ P L+ + Y C ECG +F+W S L
Sbjct: 427 RPHPEDGDGQSLEGVSSSGDSAGLEAGQGPGADEP--GLSRGKPYACGECGEAFAWLSHL 484
Query: 411 VIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPE 448
+ H SH G++R+ C C + F + L H+K H E
Sbjct: 485 MEHHSSHGGRKRYACQGCWKTFHFSLALAEHQKTHEKE 522
>gi|32813445 zinc finger and SCAN domain containing 22 [Homo
sapiens]
Length = 491
Score = 171 bits (434), Expect = 9e-43
Identities = 150/467 (32%), Positives = 203/467 (43%), Gaps = 70/467 (14%)
Query: 23 ETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPPEI 82
E ARLRFR F Y+E +GP EALA LR LCCQWLQPEAHSKEQ+LE+LVLEQFLG LPPEI
Sbjct: 46 EAARLRFRHFRYEEASGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEI 105
Query: 83 QAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTE-----EPLGS 137
QAWV Q P S EEAA LVE L T + K+ P A+ TE LG
Sbjct: 106 QAWVGAQSPKSGEEAAVLVEDL-----------TQVLDKRGWDPGAEPTEASCKQSDLGE 154
Query: 138 PHPSGTVES----PGEGPQDTRI---EGSVQ---LSCSVKEEPNVDGQEVAPSSPPLAAQ 187
PS E+ GP + EGS + LS + + +S P
Sbjct: 155 SEPSNVTETLMGGVSLGPAFVKACEPEGSSERSGLSGEIWTKSVTQQIHFKKTSGPY-KD 213
Query: 188 SPEGNHGHQEPASTSFHPPRIQEEWGLLDRSQKELYWDA--MLEKYGTVVSLGLPPHQPE 245
P G + AS + W L +K D +++ YGT PP+
Sbjct: 214 VPTDQRGRESGASRN-----SSSAWPNLTSQEKPPSEDKFDLVDAYGTE-----PPYTYS 263
Query: 246 AQAQS---ELGMLLTGTGVCRSLRSGNESEGPPGCPEAQP--PQGPGPAAWEGLSGAATP 300
+ S E + + + + + P C E + A + + A P
Sbjct: 264 GKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSECGKAFSRSTHLAQHQVVHTGAKP 323
Query: 301 APTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGV 360
G R+ T KPY C +CG+ F + H R HT
Sbjct: 324 HECKECGKAFSRVTHLTQHQRIH---TGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPY 380
Query: 361 Q--SPGLATGEST-----------EKPPQGEV---------AFPHHPRRSLTGPRSYPCE 398
+ + G A +ST EKP + + A H R +G + Y C+
Sbjct: 381 ECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRH-LRIHSGEKPYQCK 439
Query: 399 ECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGH 445
C +F+ S L+ H++ HTG++ + CSDCG+AF S L++H + H
Sbjct: 440 VCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIH 486
Score = 71.6 bits (174), Expect = 1e-12
Identities = 42/124 (33%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T KP+ C++CG+ F + H R HT + P GE + + H +
Sbjct: 319 TGAKPHECKECGKAFSRVTHLTQHQRIHTG----EKP-YKCGECGKTFSRSTHLTQH--Q 371
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHR 446
R TG R Y C+ CG +FS + L H++ HTG++ + C CGRAF S L+ H + H
Sbjct: 372 RVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHS 431
Query: 447 PEVP 450
E P
Sbjct: 432 GEKP 435
Score = 69.3 bits (168), Expect = 7e-12
Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 7/122 (5%)
Query: 329 RKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRS 388
+ PY C +CG+ F + H HT + S V +R
Sbjct: 293 KTPYACSECGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFS-------RVTHLTQHQRI 345
Query: 389 LTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPE 448
TG + Y C ECG +FS + L H++ HTG+R + C CG+AF + L H++ H E
Sbjct: 346 HTGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGE 405
Query: 449 VP 450
P
Sbjct: 406 KP 407
Score = 52.4 bits (124), Expect = 8e-07
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 5/86 (5%)
Query: 370 STEKPPQGEV-----AFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHF 424
S EKPP + A+ P + +G RS C EC F S L H+K+H+ + +
Sbjct: 238 SQEKPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYA 297
Query: 425 CSDCGRAFDWKSQLVIHRKGHRPEVP 450
CS+CG+AF + L H+ H P
Sbjct: 298 CSECGKAFSRSTHLAQHQVVHTGAKP 323
>gi|41152070 zinc finger protein 75 [Homo sapiens]
Length = 510
Score = 169 bits (429), Expect = 4e-42
Identities = 142/460 (30%), Positives = 194/460 (42%), Gaps = 59/460 (12%)
Query: 22 PETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPPE 81
PE+A F F Y E GP E +++L++LC QWL+PE HSKEQ+LEMLVLEQFL LP E
Sbjct: 45 PESACRHFWSFRYHEATGPLETISQLQKLCHQWLRPEIHSKEQILEMLVLEQFLSILPKE 104
Query: 82 IQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEP-----LG 136
Q WV+ P + ++A LVE LQ +P +TAH L +E + P
Sbjct: 105 TQNWVQKHHPQNVKQALVLVEFLQREPDGTKNEVTAHELGKEAVLLGGTAVAPGFKWKPA 164
Query: 137 SPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGHQ 196
P P G + E QL + +E E A + A S + H
Sbjct: 165 EPQPMGVFQKEYWNTYRVLQE---QLGWNTHKETQ-PVYERAVHDQQMLALSEQKRIKHW 220
Query: 197 EPASTSFHPPRI-------------QEEWGLLDRSQKELYWDAMLEKYGTVVSLGLP--- 240
+ AS P + +EEW LL+ +K LY D M + Y TV+SLGL
Sbjct: 221 KMASKLILPESLSLLTFEDVAVYFSEEEWQLLNPLEKTLYNDVMQDIYETVISLGLKLKN 280
Query: 241 ---PHQPEAQAQSELGMLLTGTGVCRSLRSGNESEGPPGCPEAQPPQG-PGPAAWEGLSG 296
P + + SE+ SG E AQ G P +
Sbjct: 281 DTGNDHPISVSTSEI------------QTSGCEVSKKTRMKIAQKTMGRENPGDTHSVQK 328
Query: 297 AATPAPTVRPGTPPVPTQPTPAETRLE-PAATPRKPYTCEQCGRGFDWKSVFVIHHRTHT 355
P + P Q P L T KP+ C++CG+ F S + HHR H
Sbjct: 329 WHRAFPRKKRKKPATCKQELPKLMDLHGKGPTGEKPFKCQECGKSFRVSSDLIKHHRIH- 387
Query: 356 SGPGVQSPGLATGESTEKPPQGEVAFPHHP---RRSLT--GPRSYPCEECGCSFSWKSQL 410
TGE K Q + F + +T G + Y C CG SFS + L
Sbjct: 388 -----------TGEKPYKCQQCDRRFRWSSDLNKHFMTHQGIKPYRCSWCGKSFSHNTNL 436
Query: 411 VIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
H++ HTG++ C +CG+ F S L+ H++ H E P
Sbjct: 437 HTHQRIHTGEKPFKCDECGKRFIQNSHLIKHQRTHTGEQP 476
>gi|47716687 zinc finger protein 167 isoform 1 [Homo sapiens]
Length = 754
Score = 164 bits (414), Expect = 2e-40
Identities = 140/470 (29%), Positives = 196/470 (41%), Gaps = 96/470 (20%)
Query: 23 ETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPPEI 82
E RL FR CY E++GP+EAL+RLRELC WL PE H+KEQ+LE+LVLEQFL LP E+
Sbjct: 51 EIFRLHFRQLCYHEMSGPQEALSRLRELCRWWLMPEVHTKEQILELLVLEQFLSILPGEL 110
Query: 83 QAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEPLGSPHPSG 142
+ WV+ P S EEA A+VE Q L G +EV AQK E G
Sbjct: 111 RTWVQLHHPESGEEAVAVVEDFQR---HLSG-------SEEVSAPAQKQEMHFEETTALG 160
Query: 143 TVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPS------SPPLAAQSPEGNHGHQ 196
T + E P + + G + E P G PS + P+ GN G Q
Sbjct: 161 TTK---ESPPTSPLSGGSAPGAHL-EPPYDPGTHHLPSGDFAQCTSPVPTLPQVGNSGDQ 216
Query: 197 EPAST-------------SFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLG----- 238
A+ Q++W L SQ+ L W+ M E + ++ SL
Sbjct: 217 AGATVLRMVRPQDTVAYEDLSVDYTQKKWKSLTLSQRALQWNMMPENHHSMASLAGENMM 276
Query: 239 ----LPPHQ-----PEAQAQSELGMLLTGTG------VCRSLRSGNESEGPPGCPEAQPP 283
L P Q E+ ++ G+ G VC + E EG E
Sbjct: 277 KGSELTPKQEFFKGSESSNRTSGGLFGVVPGAAETGDVCED--TFKELEGQTSDEEGSRL 334
Query: 284 QGPGPAAWEGLSGAATP---APTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRG 340
+ + +T G P P +P E E +K Y C++CG+
Sbjct: 335 ENDFLEITDEDKKKSTKDRYDKYKEVGEHP-PLSSSPVEH--EGVLKGQKSYRCDECGKA 391
Query: 341 FDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEEC 400
F+ S + H R H TG + Y C EC
Sbjct: 392 FNRSSHLIGHQRIH-----------------------------------TGEKPYECNEC 416
Query: 401 GCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
G +F SQL++H ++HTG++ + CS+CG+A+ S L+ H++ H E P
Sbjct: 417 GKTFRQTSQLIVHLRTHTGEKPYECSECGKAYRHSSHLIQHQRLHNGEKP 466
Score = 92.0 bits (227), Expect = 1e-18
Identities = 48/145 (33%), Positives = 74/145 (51%), Gaps = 21/145 (14%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPG----------------VQSPGLATGES 370
T KPY C +CG+ F+ S + H R HT ++ L TGE
Sbjct: 574 TGEKPYKCSECGKAFNQNSQLIEHERIHTGEKPFECSECGKAFGLSKCLIRHQRLHTGEK 633
Query: 371 TEKPPQGEVAFPHHP-----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFC 425
K + +F + +R TG + Y C ECG FS+ S L++H+++HTG++ + C
Sbjct: 634 PYKCNECGKSFNQNSHLIIHQRIHTGEKPYECNECGKVFSYSSSLMVHQRTHTGEKPYKC 693
Query: 426 SDCGRAFDWKSQLVIHRKGHRPEVP 450
+DCG+AF SQL++H++ H E P
Sbjct: 694 NDCGKAFSDSSQLIVHQRVHTGEKP 718
Score = 85.1 bits (209), Expect = 1e-16
Identities = 43/127 (33%), Positives = 67/127 (52%), Gaps = 17/127 (13%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHP- 385
T KPY C +CG+ F+ S +IH R HT GE + + F +
Sbjct: 630 TGEKPYKCNECGKSFNQNSHLIIHQRIHT------------GEKPYECNECGKVFSYSSS 677
Query: 386 ----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIH 441
+R+ TG + Y C +CG +FS SQL++H++ HTG++ + CS+CG+AF +S H
Sbjct: 678 LMVHQRTHTGEKPYKCNDCGKAFSDSSQLIVHQRVHTGEKPYECSECGKAFSQRSTFNHH 737
Query: 442 RKGHRPE 448
++ H E
Sbjct: 738 QRTHTGE 744
Score = 79.7 bits (195), Expect = 5e-15
Identities = 45/145 (31%), Positives = 70/145 (48%), Gaps = 21/145 (14%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHT----------------SGPGVQSPGLATGES 370
T +KPY C +CGR F + H R HT S ++ L TGE
Sbjct: 518 TGKKPYKCNECGRAFCSNRNLIDHQRIHTGEKPYECSECGKAFSRSKCLIRHQSLHTGEK 577
Query: 371 TEKPPQGEVAFPHHPR-----RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFC 425
K + AF + + R TG + + C ECG +F L+ H++ HTG++ + C
Sbjct: 578 PYKCSECGKAFNQNSQLIEHERIHTGEKPFECSECGKAFGLSKCLIRHQRLHTGEKPYKC 637
Query: 426 SDCGRAFDWKSQLVIHRKGHRPEVP 450
++CG++F+ S L+IH++ H E P
Sbjct: 638 NECGKSFNQNSHLIIHQRIHTGEKP 662
Score = 78.2 bits (191), Expect = 1e-14
Identities = 48/142 (33%), Positives = 68/142 (47%), Gaps = 21/142 (14%)
Query: 330 KPYTCEQCGRGFDWKSVFVIHHRTHTSGPG----------VQSPGLA------TGESTEK 373
KPY C +C + F S H RTHT ++S LA TG+ K
Sbjct: 465 KPYKCNECAKAFTQSSRLTDHQRTHTGEKPYECNECGEAFIRSKSLARHQVLHTGKKPYK 524
Query: 374 PPQGEVAFPHHP-----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDC 428
+ AF + +R TG + Y C ECG +FS L+ H+ HTG++ + CS+C
Sbjct: 525 CNECGRAFCSNRNLIDHQRIHTGEKPYECSECGKAFSRSKCLIRHQSLHTGEKPYKCSEC 584
Query: 429 GRAFDWKSQLVIHRKGHRPEVP 450
G+AF+ SQL+ H + H E P
Sbjct: 585 GKAFNQNSQLIEHERIHTGEKP 606
Score = 75.5 bits (184), Expect = 9e-14
Identities = 42/142 (29%), Positives = 70/142 (49%), Gaps = 11/142 (7%)
Query: 309 PPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATG 368
PP+ + P E L+ +K Y C++CG+ F+ S + H R HT + G
Sbjct: 364 PPLSSSPVEHEGVLKG----QKSYRCDECGKAFNRSSHLIGHQRIHTGEKPYECN--ECG 417
Query: 369 ESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDC 428
++ + Q V H TG + Y C ECG ++ S L+ H++ H G++ + C++C
Sbjct: 418 KTFRQTSQLIVHLRTH-----TGEKPYECSECGKAYRHSSHLIQHQRLHNGEKPYKCNEC 472
Query: 429 GRAFDWKSQLVIHRKGHRPEVP 450
+AF S+L H++ H E P
Sbjct: 473 AKAFTQSSRLTDHQRTHTGEKP 494
Score = 73.6 bits (179), Expect = 4e-13
Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHP- 385
T KPY C +CG+ F S ++H RTHT GE + + A+ H
Sbjct: 406 TGEKPYECNECGKTFRQTSQLIVHLRTHT------------GEKPYECSECGKAYRHSSH 453
Query: 386 ----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIH 441
+R G + Y C EC +F+ S+L H+++HTG++ + C++CG AF L H
Sbjct: 454 LIQHQRLHNGEKPYKCNECAKAFTQSSRLTDHQRTHTGEKPYECNECGEAFIRSKSLARH 513
Query: 442 RKGHRPEVP 450
+ H + P
Sbjct: 514 QVLHTGKKP 522
Score = 60.8 bits (146), Expect = 2e-09
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 11/97 (11%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSP--GLATGESTEKPPQGEVAFPHH 384
T KPY C +CG+ F + S ++H RTHT + G A +S++ H
Sbjct: 658 TGEKPYECNECGKVFSYSSSLMVHQRTHTGEKPYKCNDCGKAFSDSSQ-------LIVH- 709
Query: 385 PRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQR 421
+R TG + Y C ECG +FS +S H+++HTG++
Sbjct: 710 -QRVHTGEKPYECSECGKAFSQRSTFNHHQRTHTGEK 745
>gi|27544931 zinc finger protein 38 [Homo sapiens]
Length = 473
Score = 161 bits (408), Expect = 1e-39
Identities = 143/491 (29%), Positives = 202/491 (41%), Gaps = 113/491 (23%)
Query: 5 LGPPCLPVMDPETT---LEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHS 61
+GP + V + E L E R RFR F Y + GPREAL++LR LCC+WL+PE H+
Sbjct: 21 VGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQLRVLCCEWLRPEIHT 80
Query: 62 KEQMLEMLVLEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQH---DPGQLLGWITAH 118
KEQ+LE+LVLEQFL LP E+QAWV+ P S EEA L+E L+ +PG +
Sbjct: 81 KEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLERELDEPGHQVS----- 135
Query: 119 VLKQEVLPAAQKTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVA 178
E P +K SGT + Q +E S + G+E
Sbjct: 136 TPPNEQKPVWEKISS-------SGTAKESPSSMQPQPLETSHKYESWGPLYIQESGEEQE 188
Query: 179 PSSPPLAAQSPEGNHGHQEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLG 238
+ P + + H+E A + E GL G ++S+
Sbjct: 189 FAQDPRKVRDCRLSTQHEESADEQ----KGSEAEGL----------------KGDIISV- 227
Query: 239 LPPHQPEAQAQSELGMLLTGTGVCRSLRSGNESEGPPGCPEAQPPQGPGPAAWEGLSGAA 298
+ ++PEA + + C + +G P E S
Sbjct: 228 IIANKPEASLERQ-------------------------CVNLENEKGTKPPLQEAGS--- 259
Query: 299 TPAPTVRPGTPPVPTQPTPAE------------------TRLEPAATPRKPYTCEQCGRG 340
+ G VPT+PTP E T+ T KPY C +CG+
Sbjct: 260 ------KKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKA 313
Query: 341 FDWKSVFVIHHRTH-TSGPGVQSPGLATGES----------TEKPP----------QGEV 379
F S +H+RTH P G A G+S TE+ P G+
Sbjct: 314 FSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKG 373
Query: 380 AFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLV 439
+ H R TG + Y C ECG SFS + L H++ HTG++ + C +CG+AF+ S
Sbjct: 374 SLIRH-YRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKECGKAFNHSSNFN 432
Query: 440 IHRKGHRPEVP 450
H + H E P
Sbjct: 433 KHHRIHTGEKP 443
>gi|14249386 zinc finger protein 496 [Homo sapiens]
Length = 587
Score = 159 bits (402), Expect = 5e-39
Identities = 146/503 (29%), Positives = 199/503 (39%), Gaps = 120/503 (23%)
Query: 15 PETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQF 74
P+ L PE++R FR F YQE AGPREAL RL +LC WL+PE H+KEQ+LE+LVLEQF
Sbjct: 31 PQGELPSPESSRRLFRRFRYQEAAGPREALQRLWDLCGGWLRPERHTKEQILELLVLEQF 90
Query: 75 LGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWIT----AHVLKQEVLPAAQK 130
L LP EIQ+WVR Q P S E+A A VE L+ +PG+ W+ V+ P Q+
Sbjct: 91 LAILPREIQSWVRAQEPESGEQAVAAVEALEREPGRPWQWLKHCEDPVVIDDGDSPLDQE 150
Query: 131 TEEPLGSPHP-------------SGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEV 177
E+ PH + + P P + +Q + ++EE D Q+V
Sbjct: 151 QEQLPVEPHSDLAKNQDAQPITLAQCLGLPSRPPSQLSGDPVLQDAFLLQEENVRDTQQV 210
Query: 178 APSSPPLAAQSPEGNHGHQEPASTSFHPPRIQEEWGLLDRSQKELYWDAML-EKYGTVVS 236
P + SP + F +E+W LLD +Q Y + ++ E YG
Sbjct: 211 TTLQLPPSRVSPF------KDMILCFS----EEDWSLLDPAQTGFYGEFIIGEDYG---- 256
Query: 237 LGLPPHQPEAQAQSELG----------MLLTGTGV---------------CRSLRSGNES 271
+ +PP+ AQ G L G V R E
Sbjct: 257 VSMPPNDLAAQPDLSQGEENEPRVPELQDLQGKEVPQVSYLDSPSLQPFQVEERRKREEL 316
Query: 272 EGPP--GCPEAQPPQGPGPAAWEGLS----------------------GAATPAPTVRPG 307
+ P CP+ PQ PA S P T G
Sbjct: 317 QVPEFQACPQTVVPQNTYPAGGNPRSLENSLDEEVTIEIVLSSSGDEDSQHGPYCTEELG 376
Query: 308 TPPVPTQPTPAETRLEPAA-----TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQS 362
+P + PA R A T +K Y C CG+ F W+ F+ H R+
Sbjct: 377 SPTEKQRSLPASHRSSTEAGGEVQTSKKSYVCPNCGKIFRWRVNFIRHLRSR-------- 428
Query: 363 PGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRR 422
EKP + C CG FS L H +SH Q+
Sbjct: 429 ------REQEKP--------------------HECSVCGELFSDSEDLDGHLESHEAQKP 462
Query: 423 HFCSDCGRAFDWKSQLVIHRKGH 445
+ C CG++F S L+ HR+ H
Sbjct: 463 YRCGACGKSFRLNSHLLSHRRIH 485
Score = 46.6 bits (109), Expect = 5e-05
Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 9/121 (7%)
Query: 329 RKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRS 388
+KPY C CG+ F S + H R H +Q ++E +G P P +
Sbjct: 460 QKPYRCGACGKSFRLNSHLLSHRRIHLQPDRLQPVEKREQAASEDADKG----PKEPLEN 515
Query: 389 LTGPRSYPCEECGCSFSWKSQLVIHRKSH---TGQRRHF-CSDCGRAFDWKSQLVIHRKG 444
S+ C ECG +F L HR SH + R F C C ++F L+ H +
Sbjct: 516 GKAKLSFQCCECGKAFQRHDHLARHR-SHFHLKDKARPFQCRYCVKSFTQNYDLLRHERL 574
Query: 445 H 445
H
Sbjct: 575 H 575
>gi|4508007 zinc finger protein 174 isoform a [Homo sapiens]
Length = 407
Score = 158 bits (400), Expect = 8e-39
Identities = 134/460 (29%), Positives = 186/460 (40%), Gaps = 107/460 (23%)
Query: 6 GPPCLPVMDPETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQM 65
GPP + +PE R FR FCYQEV+GP+EAL++LR+LC QWLQPE H+KEQ+
Sbjct: 32 GPPL------QKNCPDPELCRQSFRRFCYQEVSGPQEALSQLRQLCRQWLQPELHTKEQI 85
Query: 66 LEMLVLEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVL 125
LE+LV+EQFL LPPEIQA VR + P S +E LVE + W+ + Q+VL
Sbjct: 86 LELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTLVEDFHRASKKPKQWVAVCMQGQKVL 145
Query: 126 PAAQKTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLA 185
+KT LG E P PQ P D +E +P+ P A
Sbjct: 146 --LEKTGSQLGEQ------ELPDFQPQT----------------PRRDLRESSPAEPSQA 181
Query: 186 AQSPEGNHGHQEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQPE 245
+ H E + P +QE L GT ++
Sbjct: 182 GAYDRLSPHHWEKS------PLLQEPTPKLA---------------GTEAPRMRSDNKEN 220
Query: 246 AQAQSELGMLLTGTGVCRSLRSGNESEGPPGCPEAQPP----QGPGPAAWEGLSGAATPA 301
Q + G RS +G ++ P G ++P Q P A + +
Sbjct: 221 PQQEGAKGAKPCAVSAGRSKGNGLQNPEPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHC 280
Query: 302 PTVRPGTPPVPTQPT-----------PAETRLE-----PAATPRKPYTCEQCGRGFDWKS 345
V + P+ + P RL+ P + +KPY C+ CG+ F W S
Sbjct: 281 -RVEYISSPLKSHPLRELKKSKGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNS 339
Query: 346 VFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFS 405
H R H TG R Y C ECG F
Sbjct: 340 ELKRHKRVH-----------------------------------TGERPYTCGECGNCFG 364
Query: 406 WKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGH 445
+S L +H++ HTG++ + C CG++F S L H + H
Sbjct: 365 RQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLH 404
Score = 67.4 bits (163), Expect = 3e-11
Identities = 29/68 (42%), Positives = 42/68 (61%), Gaps = 2/68 (2%)
Query: 383 HHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHR 442
H P RS P Y C++CG SF+W S+L H++ HTG+R + C +CG F +S L +H+
Sbjct: 316 HQPTRSAKKP--YKCDDCGKSFTWNSELKRHKRVHTGERPYTCGECGNCFGRQSTLKLHQ 373
Query: 443 KGHRPEVP 450
+ H E P
Sbjct: 374 RIHTGEKP 381
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 19/115 (16%)
Query: 355 TSGPGVQSPGLATGESTE--------KPPQGEVAFPHHPRRS----LTGP-RSYPCEECG 401
+ G G+Q+P +E P + F H+ R ++ P +S+P E
Sbjct: 239 SKGNGLQNPEPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHCRVEYISSPLKSHPLRELK 298
Query: 402 CSFSWKSQL------VIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
S K L + H+ + + ++ + C DCG++F W S+L H++ H E P
Sbjct: 299 KSKGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERP 353
>gi|254281232 zinc finger and SCAN domain containing 12 [Homo
sapiens]
Length = 611
Score = 156 bits (394), Expect = 4e-38
Identities = 125/429 (29%), Positives = 178/429 (41%), Gaps = 87/429 (20%)
Query: 23 ETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPPEI 82
E R FR FCYQE +GPREAL+RLRELC QWL+PE H+KEQ+LE+LVLEQFL LP E+
Sbjct: 43 EVFRQYFRQFCYQETSGPREALSRLRELCHQWLRPETHTKEQILELLVLEQFLTILPEEL 102
Query: 83 QAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEPLGSPHPSG 142
QAWV+ Q P S EE ++E L+ + +EP G
Sbjct: 103 QAWVQEQHPESGEEVVTVLEDLERE-----------------------LDEP-------G 132
Query: 143 TVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGHQEPASTS 202
S G Q+ ++ +V+L KE P ++ QS + ++ P S
Sbjct: 133 EQVSVHTGEQEMFLQETVRLR---KE-----------GEPSMSLQSMKAQPKYESPELES 178
Query: 203 FHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQPEAQAQSELGMLLTGTGVC 262
+ E G +YG + +P + S+ ++ + C
Sbjct: 179 QQEQVLDVETG---------------NEYGNLKQEVSEEMEPHGKTSSKFENDMSKSARC 223
Query: 263 RSLRSGNE-SEGPPGCPEAQPPQGPGPAAWEGLSGAATPAPTVRPGTPPVPTQPTPAETR 321
R E +E P C + P E G R
Sbjct: 224 GETREPEEITEEPSACSR----EDKQPTCDEN-------------GVSLTENSDHTEHQR 266
Query: 322 LEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAF 381
+ P + Y C+ CG+ F S + H R HT + E K +G
Sbjct: 267 ICPG---EESYGCDDCGKAFSQHSHLIEHQRIHTGDRPYKC------EECGKAFRGRTVL 317
Query: 382 PHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIH 441
H + TG + Y C ECG +F S L H++ HTG++ + C+DCG+AF K+ L H
Sbjct: 318 IRH-KIIHTGEKPYKCNECGKAFGRWSALNQHQRLHTGEKHYHCNDCGKAFSQKAGLFHH 376
Query: 442 RKGHRPEVP 450
K H + P
Sbjct: 377 IKIHTRDKP 385
Score = 78.6 bits (192), Expect = 1e-14
Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 20/151 (13%)
Query: 320 TRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTS---------GPGVQSPGLA---- 366
T+ + T KPY C +CG+ F + S V H H G GL
Sbjct: 402 TQHQGVHTGAKPYECNECGKAFVYNSSLVSHQEIHHKEKCYQCKECGKSFSQSGLIQHQR 461
Query: 367 --TGESTEKPPQGEVAFPHHP-----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTG 419
TGE K E AF +R TG R Y C++CG +F+ +S L H++ HTG
Sbjct: 462 IHTGEKPYKCDVCEKAFIQRTSLTEHQRIHTGERPYKCDKCGKAFTQRSVLTEHQRIHTG 521
Query: 420 QRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
+R + C +CG AF + L+ H++ H E P
Sbjct: 522 ERPYKCDECGNAFRGITSLIQHQRIHTGEKP 552
Score = 70.9 bits (172), Expect = 2e-12
Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 17/124 (13%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHP- 385
T KPY C+ C + F ++ H R HT GE K + AF
Sbjct: 464 TGEKPYKCDVCEKAFIQRTSLTEHQRIHT------------GERPYKCDKCGKAFTQRSV 511
Query: 386 ----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIH 441
+R TG R Y C+ECG +F + L+ H++ HTG++ + C +CG+AF +S L H
Sbjct: 512 LTEHQRIHTGERPYKCDECGNAFRGITSLIQHQRIHTGEKPYQCDECGKAFRQRSDLSKH 571
Query: 442 RKGH 445
++ H
Sbjct: 572 QRIH 575
Score = 70.5 bits (171), Expect = 3e-12
Identities = 37/122 (30%), Positives = 60/122 (49%), Gaps = 7/122 (5%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T +PY C++CG+ F +SV H R HT + + +G + H +
Sbjct: 492 TGERPYKCDKCGKAFTQRSVLTEHQRIHTGERPYKC------DECGNAFRGITSLIQH-Q 544
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHR 446
R TG + Y C+ECG +F +S L H++ H + + C +CG++F S L H+ H+
Sbjct: 545 RIHTGEKPYQCDECGKAFRQRSDLSKHQRIHNRRGTYVCKECGKSFRQNSALTQHQTIHK 604
Query: 447 PE 448
E
Sbjct: 605 GE 606
>gi|56699473 zinc finger protein 192 [Homo sapiens]
Length = 578
Score = 155 bits (392), Expect = 7e-38
Identities = 139/460 (30%), Positives = 206/460 (44%), Gaps = 55/460 (11%)
Query: 14 DPETTLEEP-----ETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEM 68
D E++L E E RLRFR YQE GPREAL +LR LC QWL+P+ ++KEQ+LE+
Sbjct: 34 DQESSLHESNPLGQEVFRLRFRQLRYQETLGPREALIQLRALCHQWLRPDLNTKEQILEL 93
Query: 69 LVLEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAA 128
LVLEQFL LP E+Q V+ + + EE L+E L+ L ++A V VL
Sbjct: 94 LVLEQFLTILPEELQTLVKEHQLENGEEVVTLLEDLERQIDILGRPVSARVHGHRVL--W 151
Query: 129 QKTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQS 188
++ +P P T + E Q K + QE A S+ +S
Sbjct: 152 EEVVHSASAPEPPNT-QLQSEATQH-------------KSPVPQESQERAMSTSQSPTRS 197
Query: 189 PEGNHGHQEPAST-------------SFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVV 235
+G+ G QE +T I+EEW LLD SQK+L D E + +
Sbjct: 198 QKGSSGDQEMTATLLTAGFQTLEKIEDMAVSLIREEW-LLDPSQKDLCRDNRPENFRNMF 256
Query: 236 SLGLPPHQPEAQAQSELGMLLTGT---GVCRSLRSGNESEGPPGCPEAQPPQGPGPAAWE 292
SLG + S+ ++ TG G + +G+ G EA+ G E
Sbjct: 257 SLGGETRSENRELASK-QVISTGIQPHGETAAKCNGDVIRGLEH-EEARDLLG----RLE 310
Query: 293 GLSGAATPAPTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHR 352
G T + + R T KPY C CG+ F ++S + H
Sbjct: 311 RQRGNPTQERRHKCDECGKSFAQSSGLVRHWRIHTGEKPYQCNVCGKAFSYRSALLSHQD 370
Query: 353 THTSGP--GVQSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQL 410
H + G A ++T G + +R TG + Y C +CG +FS + L
Sbjct: 371 IHNKVKRYHCKECGKAFSQNT-----GLILH----QRIHTGEKPYQCNQCGKAFSQSAGL 421
Query: 411 VIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
++H++ H+G+R + C++CG+AF S L+ H++ H E P
Sbjct: 422 ILHQRIHSGERPYECNECGKAFSHSSHLIGHQRIHTGEKP 461
Score = 88.2 bits (217), Expect = 1e-17
Identities = 46/129 (35%), Positives = 68/129 (52%), Gaps = 17/129 (13%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHP- 385
T KPY C QCG+ F + ++H R H+ GE + + AF H
Sbjct: 401 TGEKPYQCNQCGKAFSQSAGLILHQRIHS------------GERPYECNECGKAFSHSSH 448
Query: 386 ----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIH 441
+R TG + Y C+ECG +F S L+ H++SHTG++ + C++CGRAF KS L+ H
Sbjct: 449 LIGHQRIHTGEKPYECDECGKTFRRSSHLIGHQRSHTGEKPYKCNECGRAFSQKSGLIEH 508
Query: 442 RKGHRPEVP 450
++ H E P
Sbjct: 509 QRIHTGERP 517
Score = 78.2 bits (191), Expect = 1e-14
Identities = 43/127 (33%), Positives = 66/127 (51%), Gaps = 17/127 (13%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHP- 385
T KPY C++CG+ F S + H R+HT GE K + AF
Sbjct: 457 TGEKPYECDECGKTFRRSSHLIGHQRSHT------------GEKPYKCNECGRAFSQKSG 504
Query: 386 ----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIH 441
+R TG R Y C+ECG +F+ + L+ H + HTG++ + C++CG+AF +S L+ H
Sbjct: 505 LIEHQRIHTGERPYKCKECGKAFNGNTGLIQHLRIHTGEKPYQCNECGKAFIQRSSLIRH 564
Query: 442 RKGHRPE 448
++ H E
Sbjct: 565 QRIHSGE 571
Score = 59.3 bits (142), Expect = 7e-09
Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T KPY C +CGR F KS + H R HT + + K G H R
Sbjct: 485 TGEKPYKCNECGRAFSQKSGLIEHQRIHTGERPYKC------KECGKAFNGNTGLIQHLR 538
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQR 421
TG + Y C ECG +F +S L+ H++ H+G++
Sbjct: 539 IH-TGEKPYQCNECGKAFIQRSSLIRHQRIHSGEK 572
>gi|194328783 zinc finger protein 287 [Homo sapiens]
Length = 761
Score = 138 bits (348), Expect = 9e-33
Identities = 127/459 (27%), Positives = 189/459 (41%), Gaps = 104/459 (22%)
Query: 19 LEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTL 78
L + ET R FR F Y ++AGPR+AL++LRELC +WL+PE HSKEQ+LE+LVLEQFL L
Sbjct: 42 LRDTETCRQNFRNFPYPDLAGPRKALSQLRELCLKWLRPEIHSKEQILELLVLEQFLTIL 101
Query: 79 PPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEPLGSP 138
P E++ WV+ Q P S EEA LVE L +L++E + ++
Sbjct: 102 PGEVRTWVKSQYPESSEEAVTLVEDL------------TQILEEEAPQNSTLSQ------ 143
Query: 139 HPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGHQEP 198
++P E P+ + L+ V +E ++ ++VA
Sbjct: 144 ------DTPEEDPRGKHAFQTGWLNDLVTKE-SMTFKDVAVDI----------------- 179
Query: 199 ASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQPEAQAQSELGMLLTG 258
QE+W L+ QKELY L+ Y +VSLGL ++P E
Sbjct: 180 ---------TQEDWELMRPVQKELYKTVTLQNYWNMVSLGLTVYRPTVIPILE------- 223
Query: 259 TGVCRSLRSGNESEGPPGCPEAQPPQGPGPAAWEGLSGAATP----APTVRPGTPPVPTQ 314
P + +GP P WE + A TP + + T + +
Sbjct: 224 ---------------EPWMVIKEILEGPSP-EWETKAQACTPVEDMSKLTKEETHTIKLE 267
Query: 315 PT-PAETRLEPAATPR--KPYTCEQCGRGFDWKSVF---------------VIHHRTHTS 356
+ + RLE K +T E RGF KSV + +
Sbjct: 268 DSYDYDDRLERRGKGGFWKIHTDE---RGFSLKSVLSQEYDPTEECLSKYDIYRNNFEKH 324
Query: 357 GPGVQSPGLATGESTEKPPQGEVAFPHHP-----RRSLTGPRSYPCEECGCSFSWKSQLV 411
+ T +G F H R+ L G + Y C CG F L+
Sbjct: 325 SNLIVQFDTQLDNKTSVYNEGRATFNHVSYGIVHRKILPGEKPYKCNVCGKKFRKYPSLL 384
Query: 412 IHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
H+ +H ++ + C +CG+ F S L+ H++ H E P
Sbjct: 385 KHQSTHAKEKSYECEECGKEFRHISSLIAHQRMHTGEKP 423
Score = 81.6 bits (200), Expect = 1e-15
Identities = 40/124 (32%), Positives = 64/124 (51%), Gaps = 7/124 (5%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T KPY C QCG+ F ++ IH R HT + P + + + +
Sbjct: 419 TGEKPYECHQCGKAFSQRAHLTIHQRIHTG----EKPYKCDDCGKDFSQRAHLTIH---Q 471
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHR 446
R+ TG + Y C ECG +FS S L+ H++ HTG++ + C++CG+ F + L+ H+K H
Sbjct: 472 RTHTGEKPYKCLECGKTFSHSSSLINHQRVHTGEKPYICNECGKTFSQSTHLLQHQKIHT 531
Query: 447 PEVP 450
+ P
Sbjct: 532 GKKP 535
Score = 80.1 bits (196), Expect = 4e-15
Identities = 42/139 (30%), Positives = 67/139 (48%), Gaps = 17/139 (12%)
Query: 317 PAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQ 376
P+ + + K Y CE+CG+ F S + H R HT GE + Q
Sbjct: 381 PSLLKHQSTHAKEKSYECEECGKEFRHISSLIAHQRMHT------------GEKPYECHQ 428
Query: 377 GEVAFPHHPRRSL-----TGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRA 431
AF ++ TG + Y C++CG FS ++ L IH+++HTG++ + C +CG+
Sbjct: 429 CGKAFSQRAHLTIHQRIHTGEKPYKCDDCGKDFSQRAHLTIHQRTHTGEKPYKCLECGKT 488
Query: 432 FDWKSQLVIHRKGHRPEVP 450
F S L+ H++ H E P
Sbjct: 489 FSHSSSLINHQRVHTGEKP 507
Score = 79.0 bits (193), Expect = 8e-15
Identities = 42/127 (33%), Positives = 64/127 (50%), Gaps = 17/127 (13%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPH--- 383
T KPY C+ CG+ F ++ IH RTHT GE K + F H
Sbjct: 447 TGEKPYKCDDCGKDFSQRAHLTIHQRTHT------------GEKPYKCLECGKTFSHSSS 494
Query: 384 --HPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIH 441
+ +R TG + Y C ECG +FS + L+ H+K HTG++ + C++C + F + L+ H
Sbjct: 495 LINHQRVHTGEKPYICNECGKTFSQSTHLLQHQKIHTGKKPYKCNECWKVFSQSTYLIRH 554
Query: 442 RKGHRPE 448
++ H E
Sbjct: 555 QRIHSGE 561
Score = 74.7 bits (182), Expect = 2e-13
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 7/121 (5%)
Query: 330 KPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSL 389
KPY C CG+ F + H TH + E K + + H R
Sbjct: 366 KPYKCNVCGKKFRKYPSLLKHQSTHAKEKSYEC------EECGKEFRHISSLIAHQRMH- 418
Query: 390 TGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEV 449
TG + Y C +CG +FS ++ L IH++ HTG++ + C DCG+ F ++ L IH++ H E
Sbjct: 419 TGEKPYECHQCGKAFSQRAHLTIHQRIHTGEKPYKCDDCGKDFSQRAHLTIHQRTHTGEK 478
Query: 450 P 450
P
Sbjct: 479 P 479
Score = 74.3 bits (181), Expect = 2e-13
Identities = 38/124 (30%), Positives = 60/124 (48%), Gaps = 7/124 (5%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T KPY C +CG+ F + + H + HT + E + Q H +
Sbjct: 503 TGEKPYICNECGKTFSQSTHLLQHQKIHTGKKPYKC-----NECWKVFSQSTYLIRH--Q 555
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHR 446
R +G + Y C ECG +F+ S L+ H+ +HTG++ + C+ CG+AF + L H + H
Sbjct: 556 RIHSGEKCYKCNECGKAFAHSSTLIQHQTTHTGEKSYICNICGKAFSQSANLTQHHRTHT 615
Query: 447 PEVP 450
E P
Sbjct: 616 GEKP 619
Score = 71.6 bits (174), Expect = 1e-12
Identities = 46/147 (31%), Positives = 67/147 (45%), Gaps = 25/147 (17%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSP--GLATGEST-----------EK 373
T K Y C CG+ F + HHRTHT + G A +S EK
Sbjct: 587 TGEKSYICNICGKAFSQSANLTQHHRTHTGEKPYKCSVCGKAFSQSVHLTQHQRIHNGEK 646
Query: 374 P----------PQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRH 423
P QG H +R TG + Y C ECG +F + S L H+++HTG+R +
Sbjct: 647 PFKCNICGKAYRQGANLTQH--QRIHTGEKPYKCNECGKAFIYSSSLNQHQRTHTGERPY 704
Query: 424 FCSDCGRAFDWKSQLVIHRKGHRPEVP 450
C++C + F ++ L+ H++ H E P
Sbjct: 705 KCNECDKDFSQRTCLIQHQRIHTGEKP 731
Score = 66.2 bits (160), Expect = 6e-11
Identities = 40/140 (28%), Positives = 59/140 (42%), Gaps = 21/140 (15%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPG----------------VQSPGLATGES 370
T KPY C CG+ F H R H Q + TGE
Sbjct: 615 TGEKPYKCSVCGKAFSQSVHLTQHQRIHNGEKPFKCNICGKAYRQGANLTQHQRIHTGEK 674
Query: 371 TEKPPQGEVAFPHHP-----RRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFC 425
K + AF + +R+ TG R Y C EC FS ++ L+ H++ HTG++ + C
Sbjct: 675 PYKCNECGKAFIYSSSLNQHQRTHTGERPYKCNECDKDFSQRTCLIQHQRIHTGEKPYAC 734
Query: 426 SDCGRAFDWKSQLVIHRKGH 445
CG+ F + L+ H++ H
Sbjct: 735 RICGKTFTQSTNLIQHQRVH 754
Score = 53.5 bits (127), Expect = 4e-07
Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T KPY C +CG+ F + S H RTHT + P E + Q H +
Sbjct: 671 TGEKPYKCNECGKAFIYSSSLNQHQRTHTG----ERP-YKCNECDKDFSQRTCLIQH--Q 723
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQR 421
R TG + Y C CG +F+ + L+ H++ HTG +
Sbjct: 724 RIHTGEKPYACRICGKTFTQSTNLIQHQRVHTGAK 758
>gi|68800230 zinc finger protein 197 isoform 2 [Homo sapiens]
Length = 267
Score = 130 bits (327), Expect = 2e-30
Identities = 95/229 (41%), Positives = 120/229 (52%), Gaps = 23/229 (10%)
Query: 23 ETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPPEI 82
ET+ L FR Y E +GP+EAL+RLRELC +WL+PEA +K Q+LE+LVLEQFL LP EI
Sbjct: 39 ETSHLHFRQLRYHETSGPQEALSRLRELCRRWLRPEARTKAQILELLVLEQFLSILPGEI 98
Query: 83 QAWVRGQRPGSPEEAAALVEGLQHDPG----QLLGWITAHVLKQEVLPAAQKTEEPL--G 136
+ WV+ PGS EEA ALVE LQ D Q+ + Q+V+ A T P+ G
Sbjct: 99 RTWVQLHHPGSGEEAVALVEELQKDLDGPAIQVPVLVKDQDTLQKVVSAPGTTLPPVLPG 158
Query: 137 S-------PHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSP 189
S PHP + QD + + + ++ +E N Q +A L AQ
Sbjct: 159 SHIAAEICPHP--PTDLVAFNLQDPQHDSPAPEASALSQEENPRNQLMALML--LTAQPQ 214
Query: 190 EGNHGHQEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLG 238
E E S F EEW L Q+ LYWD MLE YG V SLG
Sbjct: 215 E--LVMFEEVSVCF----TSEEWACLGPIQRALYWDVMLENYGNVTSLG 257
>gi|19743801 zinc finger protein 274 isoform c [Homo sapiens]
Length = 653
Score = 130 bits (326), Expect = 3e-30
Identities = 85/218 (38%), Positives = 114/218 (52%), Gaps = 46/218 (21%)
Query: 21 EPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPP 80
+PE AR RFR F Y+++ GPREAL +LRELC QWLQP+A SKEQ+LE+LVLEQFLG LP
Sbjct: 156 DPEAARQRFRQFRYKDMTGPREALDQLRELCHQWLQPKARSKEQILELLVLEQFLGALPV 215
Query: 81 EIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEPLGSPHP 140
+++ WV Q P + +E ALVEG+ W++ ++EVLPA G P
Sbjct: 216 KLRTWVESQHPENCQEVVALVEGVT--------WMS----EEEVLPA--------GQPAE 255
Query: 141 SGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGHQEPAS 200
T Q+ + E + +V E V Q+VA
Sbjct: 256 GTTCCLEVTAQQEEKQEDAAICPVTVLPEEPVTFQDVAVDFS------------------ 297
Query: 201 TSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLG 238
+EEWGLL +Q+ Y D MLE +G +VS+G
Sbjct: 298 --------REEWGLLGPTQRTEYRDVMLETFGHLVSVG 327
Score = 78.6 bits (192), Expect = 1e-14
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 7/119 (5%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T +PY C+ CG+GF S H R H+ + + + A H
Sbjct: 530 TGERPYVCQDCGKGFVQSSSLTQHQRVHSGERPFEC------QECGRTFNDRSAISQH-L 582
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGH 445
R+ TG + Y C++CG +F S L+ H+++HTG+R + C+ CG+AF S L+ H++ H
Sbjct: 583 RTHTGAKPYKCQDCGKAFRQSSHLIRHQRTHTGERPYACNKCGKAFTQSSHLIGHQRTH 641
Score = 53.5 bits (127), Expect = 4e-07
Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 11/95 (11%)
Query: 330 KPYTCEQCGRGFDWKSVFVIHHRTHTSGPGV--QSPGLATGESTEKPPQGEVAFPHHPRR 387
+P+ C++CGR F+ +S H RTHT Q G A +S+ H +R
Sbjct: 561 RPFECQECGRTFNDRSAISQHLRTHTGAKPYKCQDCGKAFRQSSH--------LIRH-QR 611
Query: 388 SLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRR 422
+ TG R Y C +CG +F+ S L+ H+++H +R
Sbjct: 612 THTGERPYACNKCGKAFTQSSHLIGHQRTHNRTKR 646
Score = 41.2 bits (95), Expect = 0.002
Identities = 20/42 (47%), Positives = 26/42 (61%)
Query: 210 EEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQPEAQAQSE 251
EEWGLLD QK LY + MLE Y +VS+ +P+ +Q E
Sbjct: 26 EEWGLLDLKQKSLYREVMLENYRNLVSVEHQLSKPDVVSQLE 67
Score = 31.2 bits (69), Expect = 2.0
Identities = 15/51 (29%), Positives = 25/51 (49%)
Query: 400 CGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
C +FS ++ + + H G + CS+CG+ F +H+K H E P
Sbjct: 484 CRKTFSRSTKQITFIRIHKGSQVCRCSECGKIFRNPRYFSVHKKIHTGERP 534
>gi|7706507 zinc finger protein 274 isoform a [Homo sapiens]
Length = 621
Score = 130 bits (326), Expect = 3e-30
Identities = 85/218 (38%), Positives = 114/218 (52%), Gaps = 46/218 (21%)
Query: 21 EPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPP 80
+PE AR RFR F Y+++ GPREAL +LRELC QWLQP+A SKEQ+LE+LVLEQFLG LP
Sbjct: 124 DPEAARQRFRQFRYKDMTGPREALDQLRELCHQWLQPKARSKEQILELLVLEQFLGALPV 183
Query: 81 EIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEPLGSPHP 140
+++ WV Q P + +E ALVEG+ W++ ++EVLPA G P
Sbjct: 184 KLRTWVESQHPENCQEVVALVEGVT--------WMS----EEEVLPA--------GQPAE 223
Query: 141 SGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGHQEPAS 200
T Q+ + E + +V E V Q+VA
Sbjct: 224 GTTCCLEVTAQQEEKQEDAAICPVTVLPEEPVTFQDVAVDFS------------------ 265
Query: 201 TSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLG 238
+EEWGLL +Q+ Y D MLE +G +VS+G
Sbjct: 266 --------REEWGLLGPTQRTEYRDVMLETFGHLVSVG 295
Score = 78.6 bits (192), Expect = 1e-14
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 7/119 (5%)
Query: 327 TPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPR 386
T +PY C+ CG+GF S H R H+ + + + A H
Sbjct: 498 TGERPYVCQDCGKGFVQSSSLTQHQRVHSGERPFEC------QECGRTFNDRSAISQH-L 550
Query: 387 RSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGH 445
R+ TG + Y C++CG +F S L+ H+++HTG+R + C+ CG+AF S L+ H++ H
Sbjct: 551 RTHTGAKPYKCQDCGKAFRQSSHLIRHQRTHTGERPYACNKCGKAFTQSSHLIGHQRTH 609
Score = 53.5 bits (127), Expect = 4e-07
Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 11/95 (11%)
Query: 330 KPYTCEQCGRGFDWKSVFVIHHRTHTSGPGV--QSPGLATGESTEKPPQGEVAFPHHPRR 387
+P+ C++CGR F+ +S H RTHT Q G A +S+ H +R
Sbjct: 529 RPFECQECGRTFNDRSAISQHLRTHTGAKPYKCQDCGKAFRQSSH--------LIRH-QR 579
Query: 388 SLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRR 422
+ TG R Y C +CG +F+ S L+ H+++H +R
Sbjct: 580 THTGERPYACNKCGKAFTQSSHLIGHQRTHNRTKR 614
Score = 40.4 bits (93), Expect = 0.003
Identities = 19/34 (55%), Positives = 22/34 (64%)
Query: 210 EEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQ 243
EEWGLLD QK LY + MLE Y +VS+ P Q
Sbjct: 26 EEWGLLDLKQKSLYREVMLENYRNLVSVEYPELQ 59
Score = 31.2 bits (69), Expect = 2.0
Identities = 15/51 (29%), Positives = 25/51 (49%)
Query: 400 CGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP 450
C +FS ++ + + H G + CS+CG+ F +H+K H E P
Sbjct: 452 CRKTFSRSTKQITFIRIHKGSQVCRCSECGKIFRNPRYFSVHKKIHTGERP 502
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,034,210
Number of Sequences: 37866
Number of extensions: 1656865
Number of successful extensions: 33269
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1197
Number of HSP's successfully gapped in prelim test: 808
Number of HSP's that attempted gapping in prelim test: 8049
Number of HSP's gapped (non-prelim): 13380
length of query: 450
length of database: 18,247,518
effective HSP length: 106
effective length of query: 344
effective length of database: 14,233,722
effective search space: 4896400368
effective search space used: 4896400368
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.