Guide to the Human Genome
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Search of human proteins with 88979855

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|88979855 PREDICTED: similar to v-kit Hardy-Zuckerman 4
feline sarcoma viral oncogene homolog [Homo sapiens]
         (208 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|88979855 PREDICTED: similar to v-kit Hardy-Zuckerman 4 feline...   424   e-119
gi|148005039 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncoge...   402   e-112
gi|4557695 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene...   402   e-112
gi|27262659 colony stimulating factor 1 receptor precursor [Homo...    59   3e-09
gi|5453872 platelet-derived growth factor receptor-like protein ...    51   6e-07
gi|110349719 titin isoform N2-A [Homo sapiens]                         51   8e-07
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             45   6e-05
gi|153792329 microfibrillar-associated protein 3-like isoform 1 ...    45   6e-05
gi|109150416 peroxidasin [Homo sapiens]                                42   3e-04
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi...    42   5e-04
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap...    42   5e-04
gi|18201909 vascular cell adhesion molecule 1 isoform b precurso...    41   8e-04
gi|4507875 vascular cell adhesion molecule 1 isoform a precursor...    41   8e-04
gi|45439359 triple functional domain (PTPRF interacting) [Homo s...    41   8e-04
gi|118572606 hemicentin 1 [Homo sapiens]                               40   0.002
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa...    40   0.002
gi|110349717 titin isoform novex-2 [Homo sapiens]                      39   0.002
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]             39   0.002
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]             39   0.002
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]       39   0.002
gi|90193592 CD79B antigen isoform 3 precursor [Homo sapiens]           38   0.005
gi|11038674 CD79B antigen isoform 1 precursor [Homo sapiens]           38   0.005
gi|119220552 sidekick 1 [Homo sapiens]                                 38   0.005
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap...    38   0.005
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]         38   0.007
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    38   0.007
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ...    38   0.007
gi|28373126 contactin 4 isoform c precursor [Homo sapiens]             38   0.007
gi|28373122 contactin 4 isoform a precursor [Homo sapiens]             38   0.007
gi|40255013 carcinoembryonic antigen-related cell adhesion molec...    38   0.007

>gi|88979855 PREDICTED: similar to v-kit Hardy-Zuckerman 4 feline
           sarcoma viral oncogene homolog [Homo sapiens]
          Length = 208

 Score =  424 bits (1090), Expect = e-119
 Identities = 208/208 (100%), Positives = 208/208 (100%)

Query: 1   MLLIDPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKA 60
           MLLIDPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKA
Sbjct: 1   MLLIDPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKA 60

Query: 61  GIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEE 120
           GIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEE
Sbjct: 61  GIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEE 120

Query: 121 FTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVF 180
           FTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVF
Sbjct: 121 FTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVF 180

Query: 181 MCYANNTFGSANVTTTLEVVGKYLYGNV 208
           MCYANNTFGSANVTTTLEVVGKYLYGNV
Sbjct: 181 MCYANNTFGSANVTTTLEVVGKYLYGNV 208


>gi|148005039 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
           homolog isoform 2 precursor [Homo sapiens]
          Length = 972

 Score =  402 bits (1032), Expect = e-112
 Identities = 197/198 (99%), Positives = 197/198 (99%)

Query: 5   DPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMI 64
           DPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMI
Sbjct: 113 DPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMI 172

Query: 65  KSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVT 124
           KSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVT
Sbjct: 173 KSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVT 232

Query: 125 CTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYA 184
           CTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYA
Sbjct: 233 CTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYA 292

Query: 185 NNTFGSANVTTTLEVVGK 202
           NNTFGSANVTTTLEVV K
Sbjct: 293 NNTFGSANVTTTLEVVDK 310


>gi|4557695 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
           homolog isoform 1 precursor [Homo sapiens]
          Length = 976

 Score =  402 bits (1032), Expect = e-112
 Identities = 197/198 (99%), Positives = 197/198 (99%)

Query: 5   DPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMI 64
           DPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMI
Sbjct: 113 DPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMI 172

Query: 65  KSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVT 124
           KSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVT
Sbjct: 173 KSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVT 232

Query: 125 CTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYA 184
           CTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYA
Sbjct: 233 CTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYA 292

Query: 185 NNTFGSANVTTTLEVVGK 202
           NNTFGSANVTTTLEVV K
Sbjct: 293 NNTFGSANVTTTLEVVDK 310


>gi|27262659 colony stimulating factor 1 receptor precursor [Homo
           sapiens]
          Length = 972

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 49/184 (26%), Positives = 79/184 (42%), Gaps = 9/184 (4%)

Query: 20  EDNDTLVRCPLTDPEV-TNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHC 78
           ED D L+ C LTDP +    SL   +G+PL +   +   P  G  I   K    +    C
Sbjct: 119 EDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQ-DYQC 177

Query: 79  SVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIK--DVSSSVYS 136
           S    G+ V+S    LKV+      P +++  A  +   GE   + C+    DV+  V+ 
Sbjct: 178 SALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVF- 236

Query: 137 TWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTT 196
               +++ TKL     S  H +  Y++  TL +       +G + C A+N  G  + +  
Sbjct: 237 ---LQHNNTKLAIPQQSDFHNN-RYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMF 292

Query: 197 LEVV 200
             VV
Sbjct: 293 FRVV 296


>gi|5453872 platelet-derived growth factor receptor-like protein
           [Homo sapiens]
          Length = 375

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 42/191 (21%), Positives = 82/191 (42%), Gaps = 9/191 (4%)

Query: 16  LYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKD-LRFIPDPKAGIMIKSVKRAYHRL 74
           +Y   D   +V C +T         +    K +P +    + D K G +      + H+ 
Sbjct: 184 VYLNPDRQAVVPCRVTVLSAKVTLHREFPAKEIPANGTDIVYDMKRGFVYLQ-PHSEHQG 242

Query: 75  CLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIK-DVSSS 133
            ++C  +  G+S +S K+ L         P  ++  +S  ++ G++ +V CT+  +    
Sbjct: 243 VVYCRAEAGGRSQISVKYQLLYVAVPSGPPSTTILASSNKVKSGDDISVLCTVLGEPDVE 302

Query: 134 VYSTW----KRENSQTKLQEKYNSWHHGDFNYER--QATLTISSARVNDSGVFMCYANNT 187
           V  TW    +++     +Q+ +   H G  +  R  Q+ +T+      D+G ++C A N 
Sbjct: 303 VEFTWIFPGQKDERPVTIQDTWRLIHRGLGHTTRISQSVITVEDFETIDAGYYICTAQNL 362

Query: 188 FGSANVTTTLE 198
            G   V TT+E
Sbjct: 363 QGQTTVATTVE 373


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 50.8 bits (120), Expect = 8e-07
 Identities = 36/116 (31%), Positives = 55/116 (47%), Gaps = 11/116 (9%)

Query: 84   GKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENS 143
            GK + S +  +K  P F     V   +AS + ++GE   + C I   S  +  +W R +S
Sbjct: 6350 GKDMCSAQLSVKEPPKF-----VKKLEASKVAKQGESIQLECKISG-SPEIKVSWFRNDS 6403

Query: 144  QTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
                 E + SW +        A LTI+ A   DSG ++C A+N  G A+ +T L V
Sbjct: 6404 -----ELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTV 6454



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 6/86 (6%)

Query: 114  LLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSAR 173
            +LR G+  T  C I        S +   N  T +Q+      HG    +  AT  IS AR
Sbjct: 4872 VLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQK------HGISFIDGLATFQISGAR 4925

Query: 174  VNDSGVFMCYANNTFGSANVTTTLEV 199
            V +SG ++C A N  G+A+ +  L+V
Sbjct: 4926 VENSGTYVCEARNDAGTASCSIELKV 4951



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 47/203 (23%), Positives = 80/203 (39%), Gaps = 21/203 (10%)

Query: 7    AKLFLVDRSLYGKE--------DNDTLVRCPLT-DPEVTNYSLKGCQGKPLPKDLRFIPD 57
            A+L ++D+  + KE        +    + C +  D +VT    K  Q  P  KD +   +
Sbjct: 3636 AELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFE 3695

Query: 58   PKAGIMIKSVKRAYHRLCLHCSVDQE-GKSVLSEKFILKVRPAFKAVPVVSVSKASYLLR 116
             K   +   + +        C+   E G S  S    ++  P+F     V     SYL+ 
Sbjct: 3696 DKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSF-----VKKVDPSYLML 3750

Query: 117  EGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVND 176
             GE   + C +K  S  +  TW + N +         +         +A L I+  +V D
Sbjct: 3751 PGESARLHCKLKG-SPVIQVTWFKNNKELSESNTVRMYF-----VNSEAILDITDVKVED 3804

Query: 177  SGVFMCYANNTFGSANVTTTLEV 199
            SG + C A N  GS + +T + +
Sbjct: 3805 SGSYSCEAVNDVGSDSCSTEIVI 3827



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 6/119 (5%)

Query: 85   KSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQ 144
            +S+L E+   ++    KA PV+        +  G     TC I+   +  +  +K     
Sbjct: 3437 ESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG--- 3493

Query: 145  TKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVGKY 203
               +E Y S      + +  ++L I   +V D G + C A+N +GS + T TL V   Y
Sbjct: 3494 ---REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAY 3549



 Score = 37.4 bits (85), Expect = 0.009
 Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 15/121 (12%)

Query: 79   SVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTW 138
            +     K +LSE    +V P F   PV      S  L  GE  T  C +   ++ +  TW
Sbjct: 7196 TASSSAKLILSEH---EVPPFFDLKPV------SVDLALGESGTFKCHVTG-TAPIKITW 7245

Query: 139  KRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLE 198
             ++N + +    Y          E  ATLT+      D+G + CYA+N  G  + +  L 
Sbjct: 7246 AKDNREIRPGGNYKMTL-----VENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLG 7300

Query: 199  V 199
            V
Sbjct: 7301 V 7301



 Score = 35.4 bits (80), Expect = 0.035
 Identities = 19/87 (21%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 118  GEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDS 177
            G+  ++ C +        S W + +++ +   +Y ++   +      ATL  +   +NDS
Sbjct: 6093 GDSVSLQCQVAGTPEITVS-WYKGDTKLRPTPEYRTYFTNNV-----ATLVFNKVNINDS 6146

Query: 178  GVFMCYANNTFGSANVTTTLEVVGKYL 204
            G + C A N+ G+A+  T   +  + L
Sbjct: 6147 GEYTCKAENSIGTASSKTVFRIQERQL 6173



 Score = 35.0 bits (79), Expect = 0.045
 Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 8/102 (7%)

Query: 100  FKAVPVVSVSKA--SYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHG 157
            F   P   V K   S LL++G+   + C +   +  +  TW   + + K   K    H  
Sbjct: 4294 FVKEPATFVEKLEPSQLLKKGDATQLACKVTG-TPPIKITWFANDREIKESSK----HRM 4348

Query: 158  DFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
             F  E  A L ++   + DSG +MC A N  GS + ++ + V
Sbjct: 4349 SF-VESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIV 4389



 Score = 33.9 bits (76), Expect = 0.10
 Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 6/90 (6%)

Query: 110  KASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTI 169
            +AS +++ G+   + C I   S  +   W R   +    +KY          +  A + +
Sbjct: 5430 EASKIVKAGDSSRLECKIAG-SPEIRVVWFRNEHELPASDKYRMTF-----IDSVAVIQM 5483

Query: 170  SSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            ++    DSG F+C A N  GS + +T + V
Sbjct: 5484 NNLSTEDSGDFICEAQNPAGSTSCSTKVIV 5513



 Score = 33.9 bits (76), Expect = 0.10
 Identities = 33/125 (26%), Positives = 51/125 (40%), Gaps = 15/125 (12%)

Query: 78   CSVDQE-GKSVLSEKFILKVRPAF-KAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVY 135
            C V  E GK+  +    +K    F K +   S+ K   L+ EG  FT T  I        
Sbjct: 7847 CIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGT-FTGTPPIS------- 7898

Query: 136  STWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTT 195
             TWK+        ++ N         E+ A L I S+ V D+G + CY  N  G  + + 
Sbjct: 7899 VTWKKNGINVTPSQRCNIT-----TTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSA 7953

Query: 196  TLEVV 200
             + ++
Sbjct: 7954 QILIL 7958



 Score = 33.9 bits (76), Expect = 0.10
 Identities = 33/125 (26%), Positives = 54/125 (43%), Gaps = 15/125 (12%)

Query: 77   HCSVDQ-EGKSVLSEKFILKVRPAF-KAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSV 134
            +C ++   GK   S + ++   P F K +  V VS        G+  ++ C +       
Sbjct: 7939 NCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSV-------GDSASLQCQLAGTPEIG 7991

Query: 135  YSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVT 194
             S +K +   TKL+       H   N    ATL  +   +NDSG ++C A N+ G  + +
Sbjct: 7992 VSWYKGD---TKLRPTTTYKMHFRNNV---ATLVFNQVDINDSGEYICKAENSVGEVSAS 8045

Query: 195  TTLEV 199
            T L V
Sbjct: 8046 TFLTV 8050



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 32/106 (30%), Positives = 41/106 (38%), Gaps = 10/106 (9%)

Query: 98   PAFKAVPVVSVSKASYLLR----EGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNS 153
            PA   +PV   +  S L      EGE  T+ C I    S    TW RE+ Q +    +  
Sbjct: 933  PAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTV-TWYREDYQIESSIDFQI 991

Query: 154  WHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
                       A L I  A   DSG F C A N  G+ + +  L V
Sbjct: 992  TFQSGI-----ARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 25/127 (19%), Positives = 53/127 (41%), Gaps = 11/127 (8%)

Query: 78   CSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYST 137
            C ++ E    + E  +  + P +   P+  V         GE  T+ C + D +  +  +
Sbjct: 6999 CLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVI-----GEPATLQCKV-DGTPEIRIS 7052

Query: 138  WKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTL 197
            W +E+++ +    Y      +      A+L I+    +D G + C A+N+ G+   +  L
Sbjct: 7053 WYKEHTKLRSAPAYKMQFKNNV-----ASLVINKVDHSDVGEYSCKADNSVGAVASSAVL 7107

Query: 198  EVVGKYL 204
             +  + L
Sbjct: 7108 VIKARKL 7114



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 27/116 (23%), Positives = 52/116 (44%), Gaps = 11/116 (9%)

Query: 84   GKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENS 143
            GK   S +  ++  P F     +   + S ++++ E     C I   S  +   W ++ +
Sbjct: 7291 GKDSCSAQLGVQEPPRF-----IKKLEPSRIVKQDEFTRYECKIGG-SPEIKVLWYKDET 7344

Query: 144  QTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            + +   K+          +  A L + +  V DSG + C A+N  GSA+ +T+L+V
Sbjct: 7345 EIQESSKFRMSF-----VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 7395



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 32/158 (20%), Positives = 65/158 (41%), Gaps = 25/158 (15%)

Query: 50    KDLRF------IPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAV 103
             KDL+F      +PD +  + +++V           ++     S +SE  + K  P  K  
Sbjct: 14340 KDLKFKVEEGVVPDKEYVLRVRAVN----------AIGVSEPSEISENVVAK-DPDCK-- 14386

Query: 104   PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
             P + +     ++ EGE+ ++    + V     S W ++  + K  ++         N   
Sbjct: 14387 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVS-WHKDGKEVKASDRLTMK-----NDHI 14440

Query: 164   QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVG 201
              A L +  +   D+G++     N  GSA  +  ++V+G
Sbjct: 14441 SAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIG 14478



 Score = 31.6 bits (70), Expect = 0.50
 Identities = 20/82 (24%), Positives = 34/82 (41%), Gaps = 6/82 (7%)

Query: 118  GEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDS 177
            GE     C +   +  +  +W +++ + +   KY   +      E  A LT+      DS
Sbjct: 8167 GESADFECHVTG-TQPIKVSWAKDSREIRSGGKYQISY-----LENSAHLTVLKVDKGDS 8220

Query: 178  GVFMCYANNTFGSANVTTTLEV 199
            G + CYA N  G  + T  L +
Sbjct: 8221 GQYTCYAVNEVGKDSCTAQLNI 8242



 Score = 31.2 bits (69), Expect = 0.65
 Identities = 28/126 (22%), Positives = 50/126 (39%), Gaps = 10/126 (7%)

Query: 78   CSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYST 137
            C V  +  S L    I+   P  K  PV         + EGE   ++C ++  S  +   
Sbjct: 8322 CKVSNDAGSALCTSSIVIKEP--KKPPVFDQHLTPVTVSEGEYVQLSCHVQG-SEPIRIQ 8378

Query: 138  WKRENSQTKLQEKYNSWHHGDFNYER-QATLTISSARVNDSGVFMCYANNTFGSANVTTT 196
            W +   + K  ++ +      F++    A L +      DSG ++C A+N  GS    + 
Sbjct: 8379 WLKAGREIKPSDRCS------FSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSK 8432

Query: 197  LEVVGK 202
            + +  K
Sbjct: 8433 VTIKDK 8438



 Score = 31.2 bits (69), Expect = 0.65
 Identities = 34/121 (28%), Positives = 48/121 (39%), Gaps = 13/121 (10%)

Query: 88    LSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKL 147
             LS    LKV    +A P  +V        E +E T+ C   +VS  V   W ++  +   
Sbjct: 11650 LSSTAQLKV---LEADPYFTVKLHDKTAVEKDEITLKC---EVSKDVPVKWFKDGEEIVP 11703

Query: 148   QEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV--VGKYLY 205
               KY+    G      +  L I  A + D G ++C        ANVT    +  V K LY
Sbjct: 11704 SPKYSIKADG-----LRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLY 11758

Query: 206   G 206
             G
Sbjct: 11759 G 11759



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 6/87 (6%)

Query: 116   REGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVN 175
             + G  FT+   I    +    TWK E  + K  ++ +     D     + TLT+  +   
Sbjct: 28660 KAGSPFTIDVPISGRPAPKV-TWKLEEMRLKETDRVSITTTKD-----RTTLTVKDSMRG 28713

Query: 176   DSGVFMCYANNTFGSANVTTTLEVVGK 202
             DSG +     NT G    + T+ V+G+
Sbjct: 28714 DSGRYFLTLENTAGVKTFSVTVVVIGR 28740



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 112  SYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISS 171
            +Y + EG   T  C +        + W ++  + K  E+Y      DF  + +A+L I  
Sbjct: 1299 NYRILEGMGVTFHCKMSGYPLPKIA-WYKDGKRIKHGERYQM----DFLQDGRASLRIPV 1353

Query: 172  ARVNDSGVFMCYANNTFGSA 191
                D G++  +A+N  G+A
Sbjct: 1354 VLPEDEGIYTAFASNIKGNA 1373



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 31/121 (25%), Positives = 46/121 (38%), Gaps = 9/121 (7%)

Query: 84    GKSVLSEK--FILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRE 141
             G ++ S+K   + KV+ A   +  VS      +  EG      C I++   S   TW   
Sbjct: 31546 GGAIRSQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFG 31605

Query: 142   NSQTKLQEKYNSWHHGDFNYE-RQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
               Q +  EKY      +  YE   A L +      D G + C   N +G  +    L V 
Sbjct: 31606 VRQLENSEKY------EITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVK 31659

Query: 201   G 201
             G
Sbjct: 31660 G 31660



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 13/41 (31%), Positives = 22/41 (53%)

Query: 162  ERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVGK 202
            E +  L +S+  + D GV+ C A+N FG+      L ++ K
Sbjct: 3603 ENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK 3643



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 16/52 (30%), Positives = 22/52 (42%), Gaps = 5/52 (9%)

Query: 138  WKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFG 189
            W +++ +    EKY    H     +  A L IS     DSG + C A N  G
Sbjct: 4708 WFKDDQEISASEKYKFSFH-----DNTAFLEISQLEGTDSGTYTCSATNKAG 4754



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 15/62 (24%), Positives = 28/62 (45%), Gaps = 5/62 (8%)

Query: 138  WKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTL 197
            W ++N +       + W       +   +L + +A+  DSG ++C  +N  G+A    TL
Sbjct: 4801 WFKDNKELHSGAARSVWKD-----DTSTSLELFAAKATDSGTYICQLSNDVGTATSKATL 4855

Query: 198  EV 199
             V
Sbjct: 4856 FV 4857



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 3/90 (3%)

Query: 115   LREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEK--YNSWHHGDFNYERQATLTISSA 172
             + EG    +   IK V     + +K    +   +E   Y++ H      +   TL I  +
Sbjct: 16128 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDT-HVNKLVVDDTCTLVIPQS 16186

Query: 173   RVNDSGVFMCYANNTFGSANVTTTLEVVGK 202
             R +D+G++   A N  G+A+    L V+G+
Sbjct: 16187 RRSDTGLYTITAVNNLGTASKEMRLNVLGR 16216



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 12/36 (33%), Positives = 22/36 (61%)

Query: 165   ATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
             +TLT+ +   ND+G +     N  GS ++T T++V+
Sbjct: 28411 STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVL 28446



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 17/60 (28%), Positives = 23/60 (38%), Gaps = 5/60 (8%)

Query: 138   WKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTL 197
             W R   +     KY     G     R  TLT+ +    D GV+ C A N  G    ++ L
Sbjct: 30566 WYRFGKELIQSRKYKMSSDG-----RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 30620



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 23/99 (23%), Positives = 37/99 (37%), Gaps = 10/99 (10%)

Query: 104   PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
             P +    +   + EG+  TV C      +    TW     +   QE+      G F+ E 
Sbjct: 33329 PKIEALPSDISIDEGKVLTVACAFTGEPTPEV-TWSCGGRKIHSQEQ------GRFHIEN 33381

Query: 164   Q---ATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
                  TL I   +  D G++     N FGS + T  + +
Sbjct: 33382 TDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 13/38 (34%), Positives = 19/38 (50%)

Query: 162  ERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            E   TL +S    +D+G++ C A N  GS   +  L V
Sbjct: 6793 ENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV 6830



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 22/97 (22%), Positives = 41/97 (42%), Gaps = 7/97 (7%)

Query: 104  PVVSVSKA-SYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYE 162
            P   V K  S  +  G+  T+ CT+   +  + + W ++  +     KY         + 
Sbjct: 7585 PATIVEKPESIKVTTGDTCTLECTVAG-TPELSTKWFKDGKELTSDNKYKISF-----FN 7638

Query: 163  RQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            + + L I +   +DSGV+     N  G  + T +L+V
Sbjct: 7639 KVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV 7675



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 11/33 (33%), Positives = 21/33 (63%)

Query: 167  LTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            L +  A +ND+G++ C  +N  GSA  T+++ +
Sbjct: 8307 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVI 8339



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 22/112 (19%), Positives = 49/112 (43%), Gaps = 8/112 (7%)

Query: 89    SEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQ 148
             S+  I K R       + S  + + +++ G  FT+T   +         W + ++  + +
Sbjct: 26172 SDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRG-RPVPNVLWSKPDTDLRTR 26230

Query: 149   EKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
                ++        + + +LTI +A  NDSG +     N   +A++T  ++V+
Sbjct: 26231 AYVDTT-------DSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVL 26275



 Score = 27.7 bits (60), Expect = 7.2
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 162  ERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            E  A+L I    +ND+G F C A N+ GS + +  L V
Sbjct: 4165 EGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV 4202



 Score = 27.7 bits (60), Expect = 7.2
 Identities = 22/86 (25%), Positives = 35/86 (40%), Gaps = 7/86 (8%)

Query: 115  LREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARV 174
            L+EG+  T+TC       +V S W R     K Q ++ +         +   LTI+  R 
Sbjct: 8756 LKEGQTCTMTCQFS--VPNVKSEWFRNGRILKPQGRHKTEVE-----HKVHKLTIADVRA 8808

Query: 175  NDSGVFMCYANNTFGSANVTTTLEVV 200
             D G + C   +   SA +    E +
Sbjct: 8809 EDQGQYTCKYEDLETSAELRIEAEPI 8834



 Score = 27.3 bits (59), Expect = 9.4
 Identities = 20/80 (25%), Positives = 35/80 (43%), Gaps = 6/80 (7%)

Query: 118  GEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDS 177
            G   T+TC +   S+ +   W R+    +  E   +        +  ATL I    ++ S
Sbjct: 6189 GLPVTLTCRLNG-SAPIQVCWYRDGVLLRDDENLQTSF-----VDNVATLKILQTDLSHS 6242

Query: 178  GVFMCYANNTFGSANVTTTL 197
            G + C A+N  G+A+ +  L
Sbjct: 6243 GQYSCSASNPLGTASSSARL 6262



 Score = 27.3 bits (59), Expect = 9.4
 Identities = 19/82 (23%), Positives = 32/82 (39%), Gaps = 6/82 (7%)

Query: 118  GEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDS 177
            G    + C +   S  +  +W  E ++     KY +        +    LT++    +DS
Sbjct: 7696 GSSVVMECKVYG-SPPISVSWFHEGNEISSGRKYQTTLT-----DNTCALTVNMLEESDS 7749

Query: 178  GVFMCYANNTFGSANVTTTLEV 199
            G + C A N  GS   +  L V
Sbjct: 7750 GDYTCIATNMAGSDECSAPLTV 7771



 Score = 27.3 bits (59), Expect = 9.4
 Identities = 12/43 (27%), Positives = 24/43 (55%)

Query: 160   NYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVGK 202
             N  +++T+TI  ++ +D+G ++  A N  G A     + V+ K
Sbjct: 13741 NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 13783


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 25/98 (25%), Positives = 48/98 (48%), Gaps = 9/98 (9%)

Query: 104  PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
            PV+S+   S  +++G++ +  C I D ++ +   WK  N +  L++  +   +G      
Sbjct: 3022 PVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQE--LEDNVHISPNG------ 3073

Query: 164  QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVG 201
             + +TI   R ++ G + C A+N +G A     L V G
Sbjct: 3074 -SIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHG 3110



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 32/122 (26%), Positives = 49/122 (40%), Gaps = 10/122 (8%)

Query: 78   CSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYST 137
            C+     +S  S   +L      K + V    + S  +R G + T  CT K  S +    
Sbjct: 1746 CTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLV 1805

Query: 138  WKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTL 197
            W      T+L          DFN      LTI + +++D+G ++C  +N F     T TL
Sbjct: 1806 W------TRLHNGKLPTRAMDFN----GILTIRNVQLSDAGTYVCTGSNMFAMDQGTATL 1855

Query: 198  EV 199
             V
Sbjct: 1856 HV 1857



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 7/89 (7%)

Query: 104  PVVSV-SKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYE 162
            P VSV  +    ++ G+  T+ C       S     +  ++  KL+++           +
Sbjct: 3112 PTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGL------MD 3165

Query: 163  RQATLTISSARVNDSGVFMCYANNTFGSA 191
              A L ISSA+ +D+G ++C A N  G+A
Sbjct: 3166 SHAVLQISSAKPSDAGTYVCLAQNALGTA 3194



 Score = 31.6 bits (70), Expect = 0.50
 Identities = 19/96 (19%), Positives = 38/96 (39%), Gaps = 12/96 (12%)

Query: 104  PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
            P + +  +S  + EG+   + C +     ++ + +KR  S     + + S          
Sbjct: 2630 PPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSH--------- 2680

Query: 164  QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
               L +    V DSG ++C ANN   +   +  + V
Sbjct: 2681 ---LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2713



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 13/95 (13%)

Query: 103  VPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYE 162
            +P V +  +S  + EG+   ++C +   + +  + +KR  S     +             
Sbjct: 2244 IPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQ------------V 2291

Query: 163  RQATLTISSARVNDSGVFMCYANNTFGSANVTTTL 197
            R + L I  A   D+G ++C A+N    A++T T+
Sbjct: 2292 RGSRLYIFQASPADAGQYVCRASNGM-EASITVTV 2325



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 13/99 (13%)

Query: 104  PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
            P V VS     +  G    + C    V S+   TW++E      Q +           ER
Sbjct: 1956 PRVQVSPERTQVHAGRTVRLYCRAAGVPSATI-TWRKEGGSLPPQARS----------ER 2004

Query: 164  Q--ATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
               ATL I +    D+G ++C A +  G+A     + V+
Sbjct: 2005 TDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVL 2043



 Score = 27.3 bits (59), Expect = 9.4
 Identities = 25/96 (26%), Positives = 35/96 (36%), Gaps = 12/96 (12%)

Query: 104  PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
            P V   +A   +  G   T+ C+    S +    W +  S    Q +      GD     
Sbjct: 3212 PQVQAEEAELTVEAGHTATLRCSATG-SPAPTIHWSKLRSPLPWQHRLE----GD----- 3261

Query: 164  QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
              TL I      DSG ++C A +  G A  T  L V
Sbjct: 3262 --TLIIPRVAQQDSGQYICNATSPAGHAEATIILHV 3295


>gi|153792329 microfibrillar-associated protein 3-like isoform 1
           [Homo sapiens]
          Length = 409

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 22/99 (22%), Positives = 42/99 (42%)

Query: 102 AVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNY 161
           +VPV+       +++EG    + C++  +    +  +       K +E       G +  
Sbjct: 45  SVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQM 104

Query: 162 ERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
                L I+    +D G + C A+N +G+ N T TL V+
Sbjct: 105 HDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVI 143


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 15/153 (9%)

Query: 47  PLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVV 106
           PLP D R    P  G+ I++V +        CS      SV +  FI+      +A+P  
Sbjct: 382 PLPVDPRVNITPSGGLYIQNVVQGDSGEYA-CSATNNIDSVHATAFII-----VQALPQF 435

Query: 107 SVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQAT 166
           +V+    ++ EG+     C  K     V + W +  SQ  +  ++     G        T
Sbjct: 436 TVTPQDRVVIEGQTVDFQCEAKGNPPPVIA-WTKGGSQLSVDRRHLVLSSG--------T 486

Query: 167 LTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
           L IS   ++D G + C A N  GS  V   L V
Sbjct: 487 LRISGVALHDQGQYECQAVNIIGSQKVVAHLTV 519



 Score = 36.6 bits (83), Expect = 0.016
 Identities = 26/111 (23%), Positives = 45/111 (40%), Gaps = 9/111 (8%)

Query: 89  SEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQ 148
           S+K +  +    +  PV +   +   +  G    + C+ +        TW ++  Q    
Sbjct: 510 SQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAI-TWNKDGVQVT-- 566

Query: 149 EKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
                   G F+   +  LTI+     D+G + C A NT GSA+V+  L V
Sbjct: 567 ------ESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSV 611



 Score = 27.3 bits (59), Expect = 9.4
 Identities = 17/66 (25%), Positives = 26/66 (39%), Gaps = 9/66 (13%)

Query: 138 WKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTL 197
           W R N++  ++           N     TL I + +  D G++ C A N  G      T 
Sbjct: 279 WLRNNNELSMKTDSR------LNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVK---TQ 329

Query: 198 EVVGKY 203
           EV  +Y
Sbjct: 330 EVTLRY 335


>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
           sapiens]
          Length = 848

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 3/99 (3%)

Query: 102 AVPVVSVSKASYLLREGEEFTVTCTIK-DVSSSVYSTWKRENSQTKLQEKYNSWHHGDFN 160
           A P ++  +    +   E+ T+TC    D   S+  TW+        +EK    H    +
Sbjct: 306 AKPKITYVENQTAMELEEQVTLTCEASGDPIPSI--TWRTSTRNISSEEKTLDGHMVVRS 363

Query: 161 YERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
           + R ++LT+ S +  D+G ++C A+NT G  + +  LEV
Sbjct: 364 HARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV 402



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 41/195 (21%), Positives = 73/195 (37%), Gaps = 28/195 (14%)

Query: 19  KEDNDTLVRCPLTD--PEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCL 76
           +E  D ++ C +    P    +  KG +   L KD+RFI      + I+ +K+       
Sbjct: 130 REGEDAVIVCDVVSSLPPTIIWKHKG-RDVILKKDVRFIVLSNNYLQIRGIKKT------ 182

Query: 77  HCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLRE---------GEEFTVTCTI 127
                 EG      + + +    FK + V+     +   R+         G+  T+ C  
Sbjct: 183 -----DEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDA 237

Query: 128 KDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNT 187
           +       S W ++  Q + +E    +   D + +    LTI     ND   ++C A N 
Sbjct: 238 EGFPEPTMS-WTKDGEQIEQEEDDEKYIFSDDSSQ----LTIKKVDKNDEAEYICIAENK 292

Query: 188 FGSANVTTTLEVVGK 202
            G  + T  L+V  K
Sbjct: 293 AGEQDATIHLKVFAK 307



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 14/50 (28%), Positives = 29/50 (58%), Gaps = 1/50 (2%)

Query: 159 FNYERQATLTISSARVNDSGVFMCYANNTFGS-ANVTTTLEVVGKYLYGN 207
           +N +  +TLTI +A ++D+G++ C      GS +  T  +++  K ++ N
Sbjct: 73  WNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKN 122


>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
           sapiens]
          Length = 761

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 3/99 (3%)

Query: 102 AVPVVSVSKASYLLREGEEFTVTCTIK-DVSSSVYSTWKRENSQTKLQEKYNSWHHGDFN 160
           A P ++  +    +   E+ T+TC    D   S+  TW+        +EK    H    +
Sbjct: 306 AKPKITYVENQTAMELEEQVTLTCEASGDPIPSI--TWRTSTRNISSEEKTLDGHMVVRS 363

Query: 161 YERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
           + R ++LT+ S +  D+G ++C A+NT G  + +  LEV
Sbjct: 364 HARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV 402



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 41/195 (21%), Positives = 73/195 (37%), Gaps = 28/195 (14%)

Query: 19  KEDNDTLVRCPLTD--PEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCL 76
           +E  D ++ C +    P    +  KG +   L KD+RFI      + I+ +K+       
Sbjct: 130 REGEDAVIVCDVVSSLPPTIIWKHKG-RDVILKKDVRFIVLSNNYLQIRGIKKT------ 182

Query: 77  HCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLRE---------GEEFTVTCTI 127
                 EG      + + +    FK + V+     +   R+         G+  T+ C  
Sbjct: 183 -----DEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDA 237

Query: 128 KDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNT 187
           +       S W ++  Q + +E    +   D + +    LTI     ND   ++C A N 
Sbjct: 238 EGFPEPTMS-WTKDGEQIEQEEDDEKYIFSDDSSQ----LTIKKVDKNDEAEYICIAENK 292

Query: 188 FGSANVTTTLEVVGK 202
            G  + T  L+V  K
Sbjct: 293 AGEQDATIHLKVFAK 307



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 14/50 (28%), Positives = 29/50 (58%), Gaps = 1/50 (2%)

Query: 159 FNYERQATLTISSARVNDSGVFMCYANNTFGS-ANVTTTLEVVGKYLYGN 207
           +N +  +TLTI +A ++D+G++ C      GS +  T  +++  K ++ N
Sbjct: 73  WNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKN 122


>gi|18201909 vascular cell adhesion molecule 1 isoform b precursor
           [Homo sapiens]
          Length = 647

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 43/169 (25%), Positives = 77/169 (45%), Gaps = 27/169 (15%)

Query: 44  QGKPLPKDL--RFIPDPK-------AGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFIL 94
           QG P PK L  R +P+ +       A + + S K     + L   ++Q G+S    + I+
Sbjct: 445 QGFPAPKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELII 504

Query: 95  KVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSS-VYSTWKRENSQTKLQEKYNS 153
           +V P  K + + +    S  ++EG+   ++CT  +V  + +    K E   T L+    +
Sbjct: 505 QVTP--KDIKLTAFPSES--VKEGDTVIISCTCGNVPETWIILKKKAETGDTVLKSIDGA 560

Query: 154 WHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVGK 202
           +             TI  A++ D+GV+ C + N  GS   + TL+V G+
Sbjct: 561 Y-------------TIRKAQLKDAGVYECESKNKVGSQLRSLTLDVQGR 596



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 13/85 (15%)

Query: 105 VVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQ 164
           V+SV+ ++ L +EG   T+TC+ + + +     W ++     LQ           +    
Sbjct: 227 VISVNPSTKL-QEGGSVTMTCSSEGLPAPEIF-WSKKLDNGNLQ-----------HLSGN 273

Query: 165 ATLTISSARVNDSGVFMCYANNTFG 189
           ATLT+ + R+ DSG+++C   N  G
Sbjct: 274 ATLTLIAMRMEDSGIYVCEGVNLIG 298


>gi|4507875 vascular cell adhesion molecule 1 isoform a precursor
           [Homo sapiens]
          Length = 739

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 43/169 (25%), Positives = 77/169 (45%), Gaps = 27/169 (15%)

Query: 44  QGKPLPKDL--RFIPDPK-------AGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFIL 94
           QG P PK L  R +P+ +       A + + S K     + L   ++Q G+S    + I+
Sbjct: 537 QGFPAPKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELII 596

Query: 95  KVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSS-VYSTWKRENSQTKLQEKYNS 153
           +V P  K + + +    S  ++EG+   ++CT  +V  + +    K E   T L+    +
Sbjct: 597 QVTP--KDIKLTAFPSES--VKEGDTVIISCTCGNVPETWIILKKKAETGDTVLKSIDGA 652

Query: 154 WHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVGK 202
           +             TI  A++ D+GV+ C + N  GS   + TL+V G+
Sbjct: 653 Y-------------TIRKAQLKDAGVYECESKNKVGSQLRSLTLDVQGR 688



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 13/85 (15%)

Query: 105 VVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQ 164
           V+SV+ ++ L +EG   T+TC+ + + +     W ++     LQ           +    
Sbjct: 227 VISVNPSTKL-QEGGSVTMTCSSEGLPAPEIF-WSKKLDNGNLQ-----------HLSGN 273

Query: 165 ATLTISSARVNDSGVFMCYANNTFG 189
           ATLT+ + R+ DSG+++C   N  G
Sbjct: 274 ATLTLIAMRMEDSGIYVCEGVNLIG 298


>gi|45439359 triple functional domain (PTPRF interacting) [Homo
            sapiens]
          Length = 3097

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 32/120 (26%), Positives = 52/120 (43%), Gaps = 10/120 (8%)

Query: 87   VLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTK 146
            +L+  +I  V P F  +P+  V+        GE   + C +     +   TWK     T 
Sbjct: 2674 LLNPNYIYDVPPEF-VIPLSEVT-----CETGETVVLRCRVCGRPKASI-TWKGPEHNTL 2726

Query: 147  LQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVGKYLYG 206
              + + S  + D     +ATL I      D G++ C A N  GSA+ + +L V+G  + G
Sbjct: 2727 NNDGHYSISYSDLG---EATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMDG 2783


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 8/82 (9%)

Query: 118  GEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDS 177
            GEE T+ C +K +   +  TW +E   T+L   ++  H     +    ++ I+  R +DS
Sbjct: 1094 GEEVTLPCEVKSLPPPII-TWAKE---TQLISPFSPRH----TFLPSGSMKITETRTSDS 1145

Query: 178  GVFMCYANNTFGSANVTTTLEV 199
            G+++C A N  G+      L V
Sbjct: 1146 GMYLCVATNIAGNVTQAVKLNV 1167



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 104 PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
           P++ +S +   + EG++ T+ CT+   +      W + NS   LQ  Y            
Sbjct: 890 PLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIK-NSAMLLQNPY-------ITVRS 941

Query: 164 QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
             +L I   ++ D G + C A+N  G+ N TT++ V
Sbjct: 942 DGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV 977



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 18/131 (13%)

Query: 70   AYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKD 129
            A H  C+  +V   G S  S K  + V P  ++      ++  Y + E  +  + C    
Sbjct: 4143 AGHYTCMAANV--AGSSSTSTKLTVHVPPRIRS------TEGHYTVNENSQAILPCVADG 4194

Query: 130  VSSSVYSTWKRENSQ-TKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTF 188
            + +   + WK++N     L  KY +  +G+        L + +  + DSG + C ANN  
Sbjct: 4195 IPTPAIN-WKKDNVLLANLLGKYTAEPYGE--------LILENVVLEDSGFYTCVANNAA 4245

Query: 189  GSANVTTTLEV 199
            G    T +L V
Sbjct: 4246 GEDTHTVSLTV 4256



 Score = 36.2 bits (82), Expect = 0.020
 Identities = 29/124 (23%), Positives = 48/124 (38%), Gaps = 14/124 (11%)

Query: 77  HCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYS 136
           HC V  EG S  +  F+    P     P V+V   +     G E ++ C+         +
Sbjct: 590 HCMVSSEGGSSAASVFLTVQEP-----PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644

Query: 137 TWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTT 196
            W   +       +Y     G        TL I +A   D+G++ C A+N+ G+    +T
Sbjct: 645 -WTVNDMFIVGSHRYRMTSDG--------TLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 197 LEVV 200
           L  +
Sbjct: 696 LRYI 699



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 22/98 (22%), Positives = 37/98 (37%), Gaps = 4/98 (4%)

Query: 104 PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
           PV     A   +  G   T+ C ++         W+R ++       ++       +  R
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIK-WRRLDNMPIFSRPFSV---SSISQLR 848

Query: 164 QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVG 201
              L I +   +D G ++C A N FG     TT+ V G
Sbjct: 849 TGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886



 Score = 32.0 bits (71), Expect = 0.38
 Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 10/97 (10%)

Query: 104 PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYS-TWKRENSQTKLQEKYNSWHHGDFNYE 162
           PV+ V   +  +  GE   +TC I  +S+  Y+ TW+R +   +L E             
Sbjct: 521 PVIQVPN-NVTVTPGERAVLTCLI--ISAVDYNLTWQRNDRDVRLAEPAR------IRTL 571

Query: 163 RQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
              +L + S + ND+G + C  ++  GS+  +  L V
Sbjct: 572 ANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV 608



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 21/82 (25%), Positives = 33/82 (40%), Gaps = 8/82 (9%)

Query: 118  GEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDS 177
            G+   + C  +     V  TW +  S   +  +    HH         TL+I  A  +D+
Sbjct: 1185 GQRVDIPCNAQGTPLPVI-TWSKGGSTMLVDGE----HHVS---NPDGTLSIDQATPSDA 1236

Query: 178  GVFMCYANNTFGSANVTTTLEV 199
            G++ C A N  G+     TL V
Sbjct: 1237 GIYTCVATNIAGTDETEITLHV 1258



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 12/37 (32%), Positives = 24/37 (64%)

Query: 163  RQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            R   + I SA+++D+G++ C A N+ G+  +  +L+V
Sbjct: 1972 RGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 16/63 (25%), Positives = 29/63 (46%), Gaps = 7/63 (11%)

Query: 137  TWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTT 196
            TW+++ +         + +H  ++      L I SA V D+G ++C A N  G+      
Sbjct: 3745 TWRKDGAVL-------AGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRID 3797

Query: 197  LEV 199
            L+V
Sbjct: 3798 LQV 3800



 Score = 28.5 bits (62), Expect = 4.2
 Identities = 28/111 (25%), Positives = 48/111 (43%), Gaps = 10/111 (9%)

Query: 79   SVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTW 138
            +++Q G+S       + V P+ K     S+S  +  +REG   ++ C    V   V + +
Sbjct: 3037 AINQAGESKKKFSLTVYVPPSIKDHDSESLSVVN--VREGTSVSLECESNAVPPPVITWY 3094

Query: 139  KRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFG 189
            K     T+         H +   + Q  L I  A V+D+G ++C A N  G
Sbjct: 3095 KNGRMITEST-------HVEILADGQM-LHIKKAEVSDTGQYVCRAINVAG 3137



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 18/75 (24%), Positives = 33/75 (44%), Gaps = 8/75 (10%)

Query: 115  LREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARV 174
            ++     T+ C    + S+  S W ++    K  +  N   +G        TL I  A++
Sbjct: 2686 IKVNNTLTLECEAYAIPSASLS-WYKDGQPLKSDDHVNIAANGH-------TLQIKEAQI 2737

Query: 175  NDSGVFMCYANNTFG 189
            +D+G + C A+N  G
Sbjct: 2738 SDTGRYTCVASNIAG 2752



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 39/172 (22%), Positives = 67/172 (38%), Gaps = 18/172 (10%)

Query: 31   TDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSE 90
            T P   N+ LK     PL   +R +    AG +I+ V+     + ++  V      V ++
Sbjct: 3369 TPPPQINW-LKNGLPLPLSSHIRLLA---AGQVIRIVRAQVSDVAVYTCVASNRAGVDNK 3424

Query: 91   KFILKVRPAFKAVPVV--SVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQ 148
             + L+V     A P +  S+      + +G   ++ C I D + +    W R+     L 
Sbjct: 3425 HYNLQVF----APPNMDNSMGTEEITVLKGSSTSMAC-ITDGTPAPSMAWLRDGQPLGLD 3479

Query: 149  EKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
                   HG         L +  A   DSG + C A+N  G  +    L+V+
Sbjct: 3480 AHLTVSTHG-------MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVL 3524



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 22/105 (20%), Positives = 43/105 (40%), Gaps = 9/105 (8%)

Query: 95   KVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSW 154
            K++   +  PV+S     Y++   +  T++C    +      TW ++        +    
Sbjct: 4070 KIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDI-TWHKDGRAIVESIRQRVL 4128

Query: 155  HHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
              G        +L I+  +  D+G + C A N  GS++ +T L V
Sbjct: 4129 SSG--------SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165


>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
           sapiens]
          Length = 2113

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 19/39 (48%), Positives = 23/39 (58%)

Query: 162 ERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
           +R   LTIS  R  DSG ++C   NTFGSA  T  L V+
Sbjct: 334 KRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI 372



 Score = 35.4 bits (80), Expect = 0.035
 Identities = 37/202 (18%), Positives = 77/202 (38%), Gaps = 7/202 (3%)

Query: 1   MLLIDPAKLFLVDRSLYGKEDNDTLVRCPLT-DPEVTNYSLKGCQGKPLPKDLRFIPDPK 59
           +++IDP  + L  + L     +  ++ C LT  PE T    +  +   LP +   I    
Sbjct: 369 LMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTE-LVLPDEAISIRGLS 427

Query: 60  AGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGE 119
              ++ +  +  H     C   ++ ++      I          P +  S +  ++  GE
Sbjct: 428 NETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALE----DGTPRIVSSFSEKVVNPGE 483

Query: 120 EFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGV 179
           +F++ C  K        TW  ++        + +  +   +    + + ++  ++ D GV
Sbjct: 484 QFSLMCAAKGAPPPTV-TWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGV 542

Query: 180 FMCYANNTFGSANVTTTLEVVG 201
           + C A N  GSA     + V G
Sbjct: 543 YRCTARNLVGSAEYQARINVRG 564



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 35/156 (22%), Positives = 62/156 (39%), Gaps = 10/156 (6%)

Query: 45   GKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVP 104
            G+P P +    P+ +    I  + R    L    +V   G+   SEK  + + PA KA  
Sbjct: 1294 GQPAPSEYETSPE-QLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEK--VTIEPAGKAPA 1350

Query: 105  VVSVSKASYLLREGEEFTVTC-TIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
             +     +      ++  + C ++ D + +V  T   E+S   +    +   H +     
Sbjct: 1351 KIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN----- 1405

Query: 164  QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
              TL + + +  DSG + C A NT G   +   L V
Sbjct: 1406 -GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLV 1440


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 32/170 (18%), Positives = 66/170 (38%), Gaps = 8/170 (4%)

Query: 32   DPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEK 91
            + +++   +K  QG     +++         +  +      +LC   S+ Q  +S    K
Sbjct: 3419 ESKISQKEIKSFQGSSYEYEVQVFESVSQSSIHTAASVQDTQLCHTASLSQIAESTELSK 3478

Query: 92   FILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKY 151
               K        P + +      ++ G+     C +KD  S +  TW  E ++ +  E+ 
Sbjct: 3479 ECAKESTG--EAPKIFLHLQDVTVKCGDTAQFLCVLKD-DSFIDVTWTHEGAKIEESERL 3535

Query: 152  NSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVG 201
                +G+  +     LTI + ++ D G++ C  +N  G    +  L V G
Sbjct: 3536 KQSQNGNIQF-----LTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEG 3580



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 32/106 (30%), Positives = 41/106 (38%), Gaps = 10/106 (9%)

Query: 98  PAFKAVPVVSVSKASYLLR----EGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNS 153
           PA   +PV   +  S L      EGE  T+ C I    S    TW RE+ Q +    +  
Sbjct: 887 PAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTV-TWYREDYQIESSIDFQI 945

Query: 154 WHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
                      A L I  A   DSG F C A N  G+ + +  L V
Sbjct: 946 TFQSGI-----ARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 39/160 (24%), Positives = 67/160 (41%), Gaps = 14/160 (8%)

Query: 44   QGKPLPKDLRF--IPDPKA-GIMIKSVKRAYHRLCLHC-SVDQEGKSVLSEKFILKVRPA 99
            + K +P D +F  + D     ++I  V    H+    C +++  GK+  S K  +  R  
Sbjct: 4469 ENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR-- 4526

Query: 100  FKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDF 159
              A PV+        +  G     TC I+   +  +  +K        +E Y S      
Sbjct: 4527 --AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG------REIYESDKCSIR 4578

Query: 160  NYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            + +  ++L I   +V D G + C A+N +GS + T TL V
Sbjct: 4579 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 32/158 (20%), Positives = 65/158 (41%), Gaps = 25/158 (15%)

Query: 50   KDLRF------IPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAV 103
            KDL+F      +PD +  + +++V           ++     S +SE  + K  P  K  
Sbjct: 8035 KDLKFKVEEGVVPDKEYVLRVRAVN----------AIGVSEPSEISENVVAK-DPDCK-- 8081

Query: 104  PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
            P + +     ++ EGE+ ++    + V     S W ++  + K  ++         N   
Sbjct: 8082 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVS-WHKDGKEVKASDRLTMK-----NDHI 8135

Query: 164  QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVG 201
             A L +  +   D+G++     N  GSA  +  ++V+G
Sbjct: 8136 SAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIG 8173



 Score = 32.0 bits (71), Expect = 0.38
 Identities = 18/64 (28%), Positives = 27/64 (42%), Gaps = 4/64 (6%)

Query: 137  TWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTT 196
            TW +EN Q      Y   H    N     T  ++  +  DSG+++C A N  G +     
Sbjct: 3799 TWFKENKQLCTSVYYTIIH----NPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAE 3854

Query: 197  LEVV 200
            L V+
Sbjct: 3855 LLVL 3858



 Score = 31.2 bits (69), Expect = 0.65
 Identities = 34/121 (28%), Positives = 48/121 (39%), Gaps = 13/121 (10%)

Query: 88   LSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKL 147
            LS    LKV    +A P  +V        E +E T+ C   +VS  V   W ++  +   
Sbjct: 5345 LSSTAQLKV---LEADPYFTVKLHDKTAVEKDEITLKC---EVSKDVPVKWFKDGEEIVP 5398

Query: 148  QEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV--VGKYLY 205
              KY+    G      +  L I  A + D G ++C        ANVT    +  V K LY
Sbjct: 5399 SPKYSIKADG-----LRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLY 5453

Query: 206  G 206
            G
Sbjct: 5454 G 5454



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 6/87 (6%)

Query: 116   REGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVN 175
             + G  FT+   I    +    TWK E  + K  ++ +     D     + TLT+  +   
Sbjct: 22355 KAGSPFTIDVPISGRPAPKV-TWKLEEMRLKETDRVSITTTKD-----RTTLTVKDSMRG 22408

Query: 176   DSGVFMCYANNTFGSANVTTTLEVVGK 202
             DSG +     NT G    + T+ V+G+
Sbjct: 22409 DSGRYFLTLENTAGVKTFSVTVVVIGR 22435



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 112  SYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISS 171
            +Y + EG   T  C +        + W ++  + K  E+Y      DF  + +A+L I  
Sbjct: 1253 NYRILEGMGVTFHCKMSGYPLPKIA-WYKDGKRIKHGERYQM----DFLQDGRASLRIPV 1307

Query: 172  ARVNDSGVFMCYANNTFGSA 191
                D G++  +A+N  G+A
Sbjct: 1308 VLPEDEGIYTAFASNIKGNA 1327



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 31/121 (25%), Positives = 46/121 (38%), Gaps = 9/121 (7%)

Query: 84    GKSVLSEK--FILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRE 141
             G ++ S+K   + KV+ A   +  VS      +  EG      C I++   S   TW   
Sbjct: 25241 GGAIRSQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFG 25300

Query: 142   NSQTKLQEKYNSWHHGDFNYE-RQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
               Q +  EKY      +  YE   A L +      D G + C   N +G  +    L V 
Sbjct: 25301 VRQLENSEKY------EITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVK 25354

Query: 201   G 201
             G
Sbjct: 25355 G 25355



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 3/90 (3%)

Query: 115  LREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEK--YNSWHHGDFNYERQATLTISSA 172
            + EG    +   IK V     + +K    +   +E   Y++ H      +   TL I  +
Sbjct: 9823 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDT-HVNKLVVDDTCTLVIPQS 9881

Query: 173  RVNDSGVFMCYANNTFGSANVTTTLEVVGK 202
            R +D+G++   A N  G+A+    L V+G+
Sbjct: 9882 RRSDTGLYTITAVNNLGTASKEMRLNVLGR 9911



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 12/36 (33%), Positives = 22/36 (61%)

Query: 165   ATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
             +TLT+ +   ND+G +     N  GS ++T T++V+
Sbjct: 22106 STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVL 22141



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 17/60 (28%), Positives = 23/60 (38%), Gaps = 5/60 (8%)

Query: 138   WKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTL 197
             W R   +     KY     G     R  TLT+ +    D GV+ C A N  G    ++ L
Sbjct: 24261 WYRFGKELIQSRKYKMSSDG-----RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24315



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 23/99 (23%), Positives = 37/99 (37%), Gaps = 10/99 (10%)

Query: 104   PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
             P +    +   + EG+  TV C      +    TW     +   QE+      G F+ E 
Sbjct: 27024 PKIEALPSDISIDEGKVLTVACAFTGEPTPEV-TWSCGGRKIHSQEQ------GRFHIEN 27076

Query: 164   Q---ATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
                  TL I   +  D G++     N FGS + T  + +
Sbjct: 27077 TDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 22/112 (19%), Positives = 49/112 (43%), Gaps = 8/112 (7%)

Query: 89    SEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQ 148
             S+  I K R       + S  + + +++ G  FT+T   +         W + ++  + +
Sbjct: 19867 SDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRG-RPVPNVLWSKPDTDLRTR 19925

Query: 149   EKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
                ++        + + +LTI +A  NDSG +     N   +A++T  ++V+
Sbjct: 19926 AYVDTT-------DSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVL 19970



 Score = 27.3 bits (59), Expect = 9.4
 Identities = 12/43 (27%), Positives = 24/43 (55%)

Query: 160  NYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVGK 202
            N  +++T+TI  ++ +D+G ++  A N  G A     + V+ K
Sbjct: 7436 NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7478


>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
          Length = 1018

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 13/111 (11%)

Query: 89  SEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQ 148
           +E  IL + P F+  P+    K   L  +G    + C  K      +S W +        
Sbjct: 404 AELKILALAPTFEMNPM----KKKILAAKGGRVIIECKPKAAPKPKFS-WSKGTEWLVNS 458

Query: 149 EKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            +   W  G        +L I++   ND G++ C+A N  G AN T TL +
Sbjct: 459 SRILIWEDG--------SLEINNITRNDGGIYTCFAENNRGKANSTGTLVI 501


>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
          Length = 1007

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 13/111 (11%)

Query: 89  SEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQ 148
           +E  IL + P F+  P+    K   L  +G    + C  K      +S W +        
Sbjct: 393 AELKILALAPTFEMNPM----KKKILAAKGGRVIIECKPKAAPKPKFS-WSKGTEWLVNS 447

Query: 149 EKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            +   W  G        +L I++   ND G++ C+A N  G AN T TL +
Sbjct: 448 SRILIWEDG--------SLEINNITRNDGGIYTCFAENNRGKANSTGTLVI 490


>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
          Length = 2623

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 2/89 (2%)

Query: 112  SYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISS 171
            S + R G  F + C    V     +    ++S      K  +  HG      Q TL I +
Sbjct: 2537 SIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERT--HGSEQLHLQGTLVIQN 2594

Query: 172  ARVNDSGVFMCYANNTFGSANVTTTLEVV 200
             + +DSG++ C A N  GS    T ++V+
Sbjct: 2595 PQTSDSGIYKCTAKNPLGSDYAATYIQVI 2623



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 14/35 (40%), Positives = 22/35 (62%)

Query: 166  TLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
            TL+I    + D G ++C A+N FG+ ++  TL VV
Sbjct: 1707 TLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVV 1741



 Score = 31.6 bits (70), Expect = 0.50
 Identities = 14/44 (31%), Positives = 23/44 (52%)

Query: 159  FNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVGK 202
            + +    +LTI+  ++ DSG ++C A N  G       L+VV K
Sbjct: 2190 YTFHANGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSK 2233



 Score = 30.8 bits (68), Expect = 0.85
 Identities = 31/151 (20%), Positives = 59/151 (39%), Gaps = 18/151 (11%)

Query: 58   PKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLRE 117
            P   + I SV      + L  + ++ G  ++     L+++PA        +    Y  ++
Sbjct: 1997 PNGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLKPA-------KIDHKQYFRKQ 2049

Query: 118  ---GEEFTVTCT-----IKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTI 169
               G++F V C      + ++S S+       N+       + +  +  FN     TL  
Sbjct: 2050 VLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFN---NGTLYF 2106

Query: 170  SSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
            +   V + G + CYA NT G   +   L V+
Sbjct: 2107 NKVGVAEEGDYTCYAQNTLGKDEMKVHLTVI 2137



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 14/38 (36%), Positives = 22/38 (57%)

Query: 163  RQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
            +  TL I + R++DS  F+C A N  G + +   LEV+
Sbjct: 2294 KNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVL 2331



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 13/45 (28%), Positives = 21/45 (46%)

Query: 156  HGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
            +G +      TL I  A   D G ++C A N+ G   +T  + +V
Sbjct: 2480 NGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIV 2524


>gi|90193592 CD79B antigen isoform 3 precursor [Homo sapiens]
          Length = 230

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 4/71 (5%)

Query: 121 FTVT--CTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSG 178
           FTV   C +   S +V   WK+E  +   Q K       +   E  ATLTI   R  D+G
Sbjct: 60  FTVKMHCYMNSASGNVSWLWKQEMDENPQQLKLEKGRMEESQNESLATLTIQGIRFEDNG 119

Query: 179 VFMCY--ANNT 187
           ++ C    NNT
Sbjct: 120 IYFCQQKCNNT 130


>gi|11038674 CD79B antigen isoform 1 precursor [Homo sapiens]
          Length = 229

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 4/71 (5%)

Query: 121 FTVT--CTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSG 178
           FTV   C +   S +V   WK+E  +   Q K       +   E  ATLTI   R  D+G
Sbjct: 59  FTVKMHCYMNSASGNVSWLWKQEMDENPQQLKLEKGRMEESQNESLATLTIQGIRFEDNG 118

Query: 179 VFMCY--ANNT 187
           ++ C    NNT
Sbjct: 119 IYFCQQKCNNT 129


>gi|119220552 sidekick 1 [Homo sapiens]
          Length = 2213

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 32/124 (25%), Positives = 47/124 (37%), Gaps = 13/124 (10%)

Query: 78  CSVDQEGKSVLSEKF--ILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVY 135
           C    EG  + +  +  +  + P F   PV +       + +G    + C +        
Sbjct: 458 CFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTT------VTDGMTAILRCEVSGAPKPAI 511

Query: 136 STWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTT 195
            TWKREN          S     F       L I+   + D+G + CYA NT GS N + 
Sbjct: 512 -TWKRENHILAS----GSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASA 566

Query: 196 TLEV 199
           TL V
Sbjct: 567 TLTV 570



 Score = 31.2 bits (69), Expect = 0.65
 Identities = 14/33 (42%), Positives = 18/33 (54%)

Query: 167 LTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
           L I   R  DSG+F C+A+N  G     T L+V
Sbjct: 443 LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDV 475


>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
           sapiens]
          Length = 858

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 19/112 (16%)

Query: 102 AVPVVSVSKASYLLREGEEFTVTC--------------TIKDVSSSVYSTWKRENSQTKL 147
           A P ++  +    +   E+ T+TC              + +++SS   ++W R   Q  L
Sbjct: 306 AKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETL 365

Query: 148 QEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
                  H    ++ R ++LT+ S +  D+G ++C A+NT G  + +  LEV
Sbjct: 366 DG-----HMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEV 412



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 41/195 (21%), Positives = 73/195 (37%), Gaps = 28/195 (14%)

Query: 19  KEDNDTLVRCPLTD--PEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCL 76
           +E  D ++ C +    P    +  KG +   L KD+RFI      + I+ +K+       
Sbjct: 130 REGEDAVIVCDVVSSLPPTIIWKHKG-RDVILKKDVRFIVLSNNYLQIRGIKKT------ 182

Query: 77  HCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLRE---------GEEFTVTCTI 127
                 EG      + + +    FK + V+     +   R+         G+  T+ C  
Sbjct: 183 -----DEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDA 237

Query: 128 KDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNT 187
           +       S W ++  Q + +E    +   D + +    LTI     ND   ++C A N 
Sbjct: 238 EGFPEPTMS-WTKDGEQIEQEEDDEKYIFSDDSSQ----LTIKKVDKNDEAEYICIAENK 292

Query: 188 FGSANVTTTLEVVGK 202
            G  + T  L+V  K
Sbjct: 293 AGEQDATIHLKVFAK 307



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 14/50 (28%), Positives = 29/50 (58%), Gaps = 1/50 (2%)

Query: 159 FNYERQATLTISSARVNDSGVFMCYANNTFGS-ANVTTTLEVVGKYLYGN 207
           +N +  +TLTI +A ++D+G++ C      GS +  T  +++  K ++ N
Sbjct: 73  WNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKN 122


>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
          Length = 1215

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 9/97 (9%)

Query: 101 KAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFN 160
           +  P VS+  +S    +G E  V+C+     +  + +W RE+    LQE          +
Sbjct: 488 REAPQVSIHTSSQHFSQGVEVKVSCSASGYPTP-HISWSRESQA--LQEDSR------IH 538

Query: 161 YERQATLTISSARVNDSGVFMCYANNTFGSANVTTTL 197
            + Q TL I      D+G + C A N  G+   T TL
Sbjct: 539 VDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 575



 Score = 36.2 bits (82), Expect = 0.020
 Identities = 22/96 (22%), Positives = 39/96 (40%), Gaps = 8/96 (8%)

Query: 104 PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
           P +  +   ++  EG   ++ C    V +   +  K  N+ T     YN          +
Sbjct: 859 PRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYN--------VSK 910

Query: 164 QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
           + TL I+     D+G ++C A NT G ++    L V
Sbjct: 911 EGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSV 946



 Score = 33.1 bits (74), Expect = 0.17
 Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 8/87 (9%)

Query: 116  REGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVN 175
            + GEE T+ C  K     + +  K       +  +Y     G        +L ++  +V 
Sbjct: 969  KAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSG--------SLRLAQVQVG 1020

Query: 176  DSGVFMCYANNTFGSANVTTTLEVVGK 202
            DSG + C A+N  GSA+    L V G+
Sbjct: 1021 DSGHYECTASNPAGSASHRYVLGVQGR 1047



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 26/96 (27%), Positives = 36/96 (37%), Gaps = 11/96 (11%)

Query: 104 PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
           P VS   A  L+  GEE  + C    V       W R   +  L  + +S          
Sbjct: 581 PSVSAVNAVVLVAVGEEAVLVCEASGVPPPRV-IWYRGGLEMILAPEGSS---------- 629

Query: 164 QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
              L I +A+  D+G + C A N  G A+    L V
Sbjct: 630 SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 665


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 9/97 (9%)

Query: 101 KAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFN 160
           +  P VS+  +S    +G E  V+C+     +  + +W RE+    LQE          +
Sbjct: 605 REAPQVSIHTSSQHFSQGVEVKVSCSASGYPTP-HISWSRESQA--LQEDSR------IH 655

Query: 161 YERQATLTISSARVNDSGVFMCYANNTFGSANVTTTL 197
            + Q TL I      D+G + C A N  G+   T TL
Sbjct: 656 VDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 692



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 38/168 (22%), Positives = 72/168 (42%), Gaps = 13/168 (7%)

Query: 32   DPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEK 91
            +PEVT Y  K  Q   L +++  +P     + +   + +   +    +++  G+     +
Sbjct: 2966 NPEVTWY--KDSQALSLGEEVFLLPGTHT-LQLGRARLSDSGMYTCEALNAAGRDQKLVQ 3022

Query: 92   FILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKY 151
              + V PAF+  P     + + L+R G++  ++C   D       TW ++     L ++ 
Sbjct: 3023 LSVLVPPAFRQAP--RGPQDAVLVRVGDKAVLSCET-DALPEPTVTWYKDGQPLVLAQRT 3079

Query: 152  NSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
             +   G         L I  A+V+D G++ C  +N  G A  T TL V
Sbjct: 3080 QALRGGQ-------RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV 3120



 Score = 36.6 bits (83), Expect = 0.016
 Identities = 24/106 (22%), Positives = 44/106 (41%), Gaps = 12/106 (11%)

Query: 104  PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
            P +  +   ++  EG   ++ C    V +   +  K  N+ T     YN          +
Sbjct: 976  PRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYN--------VSK 1027

Query: 164  QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV----VGKYLY 205
            + TL I+     D+G ++C A NT G ++    L V    + KY++
Sbjct: 1028 EGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVW 1073



 Score = 36.2 bits (82), Expect = 0.020
 Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 8/84 (9%)

Query: 116  REGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVN 175
            R GE  T+ C ++  S  ++ +W ++     L ++  +  HG  +     TL IS  ++ 
Sbjct: 3326 RPGELVTMVCPVRG-SPPIHVSWLKDGLPLPLSQR--TLLHGSGH-----TLRISKVQLA 3377

Query: 176  DSGVFMCYANNTFGSANVTTTLEV 199
            D+G+F C A +  G A+   TL+V
Sbjct: 3378 DAGIFTCVAASPAGVADRNFTLQV 3401



 Score = 30.8 bits (68), Expect = 0.85
 Identities = 23/120 (19%), Positives = 47/120 (39%), Gaps = 12/120 (10%)

Query: 83   EGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKREN 142
            E +  +++K ++ V    ++ PV  V      +R G++  + C      +     W +  
Sbjct: 4291 ENEMGVAKKVVILV---LQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIE-WLQAG 4346

Query: 143  SQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVGK 202
               +   +  +   G        +L + +    D+G + C A+N  GSA     L V G+
Sbjct: 4347 QPLRASRRLRTLPDG--------SLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGE 4398



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 13/33 (39%), Positives = 21/33 (63%)

Query: 167  LTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            L +  A+ +D+GV+ C A+N  G+A   T L+V
Sbjct: 1558 LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDV 1590



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 15/33 (45%), Positives = 19/33 (57%)

Query: 167  LTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            L +S+A V D+  +MC A N  GSA    TL V
Sbjct: 2901 LQVSTAEVADAASYMCVAENQAGSAEKLFTLRV 2933



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 14/41 (34%), Positives = 21/41 (51%)

Query: 166  TLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVGKYLYG 206
            TL I    ++ SG+F C A N  G+A     + V G++  G
Sbjct: 1744 TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPG 1784



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 26/96 (27%), Positives = 36/96 (37%), Gaps = 11/96 (11%)

Query: 104 PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
           P VS   A  L+  GEE  + C    V       W R   +  L  + +S          
Sbjct: 698 PSVSAVNAVVLVAVGEEAVLVCEASGVPPPRV-IWYRGGLEMILAPEGSS---------- 746

Query: 164 QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
              L I +A+  D+G + C A N  G A+    L V
Sbjct: 747 SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 167  LTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
            LT++SAR +DSG + C A +  G       L+V
Sbjct: 2035 LTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 2067



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 7/64 (10%)

Query: 137  TWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTT 196
            TW +++    L E+        F      TL +  AR++DSG++ C A N  G       
Sbjct: 2970 TWYKDSQALSLGEEV-------FLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQ 3022

Query: 197  LEVV 200
            L V+
Sbjct: 3023 LSVL 3026



 Score = 28.1 bits (61), Expect = 5.5
 Identities = 22/106 (20%), Positives = 35/106 (33%), Gaps = 8/106 (7%)

Query: 95   KVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSW 154
            K R   +  PV+          EG    + C  +  S     TW ++       E     
Sbjct: 4029 KTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARG-SPEPNITWDKDGQPVSGAE----- 4082

Query: 155  HHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
              G F  +    L + +    D+G + C A N  G A     L ++
Sbjct: 4083 --GKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL 4126


>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
           sapiens]
          Length = 790

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 9/97 (9%)

Query: 101 KAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFN 160
           +  P VS+  +S    +G E  V+C+     +  + +W RE+    LQE          +
Sbjct: 604 REAPQVSIHTSSQHFSQGVEVKVSCSASGYPTP-HISWSRESQA--LQEDSR------IH 654

Query: 161 YERQATLTISSARVNDSGVFMCYANNTFGSANVTTTL 197
            + Q TL I      D+G + C A N  G+   T TL
Sbjct: 655 VDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 691



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 26/96 (27%), Positives = 36/96 (37%), Gaps = 11/96 (11%)

Query: 104 PVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYER 163
           P VS   A  L+  GEE  + C    V       W R   +  L  + +S          
Sbjct: 697 PSVSAVNAVVLVAVGEEAVLVCEASGVPPPRV-IWYRGGLEMILAPEGSS---------- 745

Query: 164 QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
              L I +A+  D+G + C A N  G A+    L V
Sbjct: 746 SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 781


>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
          Length = 698

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 13/111 (11%)

Query: 89  SEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQ 148
           +E  ++ V P F    +  V+    L++ G E  + C  K     VY TWK+     K  
Sbjct: 69  AELSVIAVGPDFSRTLLKRVT----LVKVGGEVVIECKPKASPKPVY-TWKKGRDILKEN 123

Query: 149 EKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
           E+      G+        L I +   +D+G + C A N FG+A+ T  L V
Sbjct: 124 ERITISEDGN--------LRIINVTKSDAGSYTCIATNHFGTASSTGNLVV 166



 Score = 27.7 bits (60), Expect = 7.2
 Identities = 12/37 (32%), Positives = 19/37 (51%)

Query: 164 QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
           Q TL I+   ++D+G++ C A N  G       L V+
Sbjct: 38  QGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVI 74


>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
          Length = 1026

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 13/111 (11%)

Query: 89  SEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQ 148
           +E  ++ V P F    +  V+    L++ G E  + C  K     VY TWK+     K  
Sbjct: 397 AELSVIAVGPDFSRTLLKRVT----LVKVGGEVVIECKPKASPKPVY-TWKKGRDILKEN 451

Query: 149 EKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEV 199
           E+      G+        L I +   +D+G + C A N FG+A+ T  L V
Sbjct: 452 ERITISEDGN--------LRIINVTKSDAGSYTCIATNHFGTASSTGNLVV 494



 Score = 27.7 bits (60), Expect = 7.2
 Identities = 12/37 (32%), Positives = 19/37 (51%)

Query: 164 QATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVV 200
           Q TL I+   ++D+G++ C A N  G       L V+
Sbjct: 366 QGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVI 402


>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
           6 (non-specific cross reacting antigen) [Homo sapiens]
          Length = 344

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 45/166 (27%), Positives = 66/166 (39%), Gaps = 23/166 (13%)

Query: 32  DPEVTNYS-LKGCQGKPLPKDLRF-IPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLS 89
           +PEV N + L    G+ LP   R  + +    + + SVKR        C +     +  S
Sbjct: 168 EPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRN-DAGSYECEIQNPASANRS 226

Query: 90  EKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQE 149
           +   L V       P +S SKA+Y  R GE   ++C       + YS +     Q   QE
Sbjct: 227 DPVTLNVLYGPDG-PTISPSKANY--RPGENLNLSCHAASNPPAQYSWFINGTFQQSTQE 283

Query: 150 KYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTT 195
                            L I +  VN+SG +MC A+N+    N TT
Sbjct: 284 -----------------LFIPNITVNNSGSYMCQAHNSATGLNRTT 312


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,707,984
Number of Sequences: 37866
Number of extensions: 329645
Number of successful extensions: 1786
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 983
Number of HSP's gapped (non-prelim): 859
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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