Guide to the Human Genome
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Name: TH Sequence: fasta or formatted (528aa) NCBI GI: 88900501
Description:

tyrosine hydroxylase isoform a

Referenced in:

Catecholamines

Other entries for this name:
alt prot [497aa] tyrosine hydroxylase isoform b
alt prot [524aa] tyrosine hydroxylase isoform c
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.7         62           6
 C cysteine            1.3          7           2
 D aspartate           5.5         29           1
 E glutamate           8.1         43           2
 F phenylalanine       5.1         27           1
 G glycine             5.9         31           2
 H histidine           2.8         15           2
 I isoleucine          3.0         16           1
 K lysine              4.2         22           1
 L leucine             9.7         51           2
 M methionine          0.8          4           1
 N asparagine          0.6          3           1
 P proline             7.4         39           1
 Q glutamine           4.4         23           1
 R arginine            7.6         40           2
 S serine              7.4         39           2
 T threonine           4.5         24           2
 V valine              6.1         32           1
 W tryptophan          0.8          4           1
 Y tyrosine            3.2         17           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   tyrosine hydroxylase isoform a 
TH                    0.987   tyrosine hydroxylase isoform c 
TH                    0.921   tyrosine hydroxylase isoform b 
PAH                   0.413   phenylalanine hydroxylase 
TPH2                  0.399   tryptophan hydroxylase 2 
TPH1                  0.396   tryptophan hydroxylase 1 
KIAA0754              0.012   hypothetical protein LOC643314 
GATA4                 0.011   GATA binding protein 4 
GFAP                  0.011   glial fibrillary acidic protein isoform 2 
GFAP                  0.011   glial fibrillary acidic protein isoform 1 
SHANK3                0.010   SH3 and multiple ankyrin repeat domains 3 
AP1G2                 0.010   adaptor-related protein complex 1, gamma 2 subunit [H...
JUND                  0.010   jun D proto-oncogene 
OTOG                  0.009   PREDICTED: otogelin isoform 1 
OTOG                  0.009   PREDICTED: otogelin isoform 2 
OTOG                  0.009   PREDICTED: otogelin isoform 2 
OTOG                  0.009   PREDICTED: otogelin isoform 1 
AMOT                  0.009   angiomotin isoform 2 
AMOT                  0.009   angiomotin isoform 1 
TRIO                  0.009   triple functional domain (PTPRF interacting) 
CNKSR1                0.009   connector enhancer of kinase suppressor of Ras 1 [H...
LTBP1                 0.008   latent transforming growth factor beta binding prote...
LOC645722             0.008   PREDICTED: similar to hCG2037003 
GPRIN3                0.008   G protein-regulated inducer of neurite outgrowth 3 ...
CTF1                  0.008   cardiotrophin 1 isoform 2 
CTF1                  0.008   cardiotrophin 1 isoform 1 
LOC100129520          0.007   PREDICTED: similar to hCG2044193 
LOC100129520          0.007   PREDICTED: similar to hCG2044193 
LOC100129520          0.007   PREDICTED: hypothetical protein LOC100129520 
SHANK1                0.007   SH3 and multiple ankyrin repeat domains 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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