Guide to the Human Genome
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Name: TPH1 Sequence: fasta or formatted (444aa) NCBI GI: 4759248
Description:

tryptophan hydroxylase 1

Referenced in:

Serotonin

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.0         22           1
 C cysteine            2.3         10           1
 D aspartate           6.1         27           1
 E glutamate           7.9         35           3
 F phenylalanine       6.5         29           2
 G glycine             4.7         21           2
 H histidine           3.6         16           1
 I isoleucine          5.0         22           1
 K lysine              8.6         38           2
 L leucine            10.4         46           2
 M methionine          1.4          6           1
 N asparagine          4.3         19           1
 P proline             4.7         21           1
 Q glutamine           3.2         14           1
 R arginine            5.0         22           2
 S serine              7.4         33           2
 T threonine           4.7         21           2
 V valine              5.6         25           2
 W tryptophan          0.5          2           1
 Y tyrosine            3.4         15           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   tryptophan hydroxylase 1 
TPH2                  0.741   tryptophan hydroxylase 2 
PAH                   0.531   phenylalanine hydroxylase 
TH                    0.465   tyrosine hydroxylase isoform c 
TH                    0.465   tyrosine hydroxylase isoform a 
TH                    0.465   tyrosine hydroxylase isoform b 
EMR1                  0.009   egf-like module containing, mucin-like, hormone rece...
ERCC5                 0.008   XPG-complementing protein 
KIF27                 0.008   kinesin family member 27 
ATP6AP2               0.006   ATPase, H+ transporting, lysosomal accessory protein...
MYST3                 0.006   MYST histone acetyltransferase (monocytic leukemia)...
MYST3                 0.006   MYST histone acetyltransferase (monocytic leukemia)...
MYST3                 0.006   MYST histone acetyltransferase (monocytic leukemia)...
MYST4                 0.006   MYST histone acetyltransferase (monocytic leukemia)...
ZBTB43                0.006   zinc finger and BTB domain containing 43 
ZBTB43                0.006   zinc finger and BTB domain containing 43 
CPB2                  0.006   plasma carboxypeptidase B2 isoform a preproprotein ...
CPB2                  0.006   plasma carboxypeptidase B2 isoform b 
LOC728597             0.006   PREDICTED: doublecortin domain-containing protein E...
LOC728597             0.006   PREDICTED: doublecortin domain-containing protein E...
LOC728597             0.006   PREDICTED: doublecortin domain-containing protein E...
MYT1L                 0.005   myelin transcription factor 1-like 
NDE1                  0.005   nuclear distribution gene E homolog 1 
NDE1                  0.005   nuclear distribution gene E homolog 1 
LOC100133578          0.005   PREDICTED: similar to acetylserotonin O-methyltrans...
CNP                   0.005   2',3'-cyclic nucleotide 3' phosphodiesterase 
GALNTL5               0.005   UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-ace...
CSRP2BP               0.005   CSRP2 binding protein isoform b 
CSRP2BP               0.005   CSRP2 binding protein isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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