Guide to the Human Genome
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Name: TPH2 Sequence: fasta or formatted (490aa) NCBI GI: 31795563
Description:

tryptophan hydroxylase 2

Referenced in:

Serotonin

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5         27           2
 C cysteine            2.7         13           1
 D aspartate           5.1         25           2
 E glutamate           9.0         44           4
 F phenylalanine       5.7         28           2
 G glycine             5.7         28           2
 H histidine           2.0         10           1
 I isoleucine          3.5         17           1
 K lysine              7.1         35           1
 L leucine             9.6         47           2
 M methionine          2.0         10           3
 N asparagine          3.5         17           1
 P proline             4.7         23           2
 Q glutamine           3.9         19           1
 R arginine            5.7         28           3
 S serine              7.3         36           2
 T threonine           5.5         27           2
 V valine              6.3         31           2
 W tryptophan          0.8          4           1
 Y tyrosine            4.3         21           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   tryptophan hydroxylase 2 
TPH1                  0.669   tryptophan hydroxylase 1 
PAH                   0.491   phenylalanine hydroxylase 
TH                    0.424   tyrosine hydroxylase isoform c 
TH                    0.424   tyrosine hydroxylase isoform a 
TH                    0.424   tyrosine hydroxylase isoform b 
SBF2                  0.012   SET binding factor 2 
EMR1                  0.011   egf-like module containing, mucin-like, hormone rece...
HNRNPCL1              0.008   heterogeneous nuclear ribonucleoprotein C-like 1 [Ho...
LOC440563             0.007   heterogeneous nuclear ribonucleoprotein C-like [Hom...
HNRNPC                0.007   heterogeneous nuclear ribonucleoprotein C isoform b...
HNRNPC                0.007   heterogeneous nuclear ribonucleoprotein C isoform a...
HNRNPC                0.007   heterogeneous nuclear ribonucleoprotein C isoform b...
HNRNPC                0.007   heterogeneous nuclear ribonucleoprotein C isoform a...
CYLC1                 0.007   cylicin, basic protein of sperm head cytoskeleton 1...
LOC649330             0.005   PREDICTED: heterogeneous nuclear ribonucleoprotein ...
LOC652665             0.005   PREDICTED: similar to heterogeneous nuclear ribonuc...
LOC649330             0.005   heterogeneous nuclear ribonucleoprotein C-like [Hom...
MAGED4B               0.005   melanoma antigen family D, 4B isoform 2 
MAGED4B               0.005   melanoma antigen family D, 4B isoform 1 
MAGED4B               0.005   melanoma antigen family D, 4B isoform 1 
MAGED4                0.005   melanoma antigen family D, 4 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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