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Search of human proteins with 88703041
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88703041 sorting nexin 6 isoform b [Homo sapiens]
(418 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88703041 sorting nexin 6 isoform b [Homo sapiens] 825 0.0
gi|88703043 sorting nexin 6 isoform a [Homo sapiens] 568 e-162
gi|72534838 sorting nexin 6B [Homo sapiens] 555 e-158
gi|23111047 sorting nexin 5 [Homo sapiens] 536 e-152
gi|7657599 sorting nexin 5 [Homo sapiens] 536 e-152
gi|23111038 sorting nexin 2 [Homo sapiens] 86 6e-17
gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 84 2e-16
gi|23111032 sorting nexin 1 isoform b [Homo sapiens] 84 3e-16
gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 71 2e-12
gi|194294540 sorting nexin 7 isoform a [Homo sapiens] 53 6e-07
gi|23111055 sorting nexin 7 isoform b [Homo sapiens] 50 4e-06
gi|153791707 sorting nexin family member 30 [Homo sapiens] 44 2e-04
gi|71061468 centromere protein E [Homo sapiens] 44 4e-04
gi|21536423 amphiphysin isoform 2 [Homo sapiens] 42 0.001
gi|4502081 amphiphysin isoform 1 [Homo sapiens] 42 0.001
gi|4507143 sorting nexin 3 isoform a [Homo sapiens] 42 0.001
gi|23111030 sorting nexin 12 [Homo sapiens] 41 0.002
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 39 0.007
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens] 38 0.015
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens] 38 0.015
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens] 38 0.015
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens] 38 0.015
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] 38 0.015
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens] 38 0.015
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens] 38 0.015
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens] 38 0.020
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 37 0.025
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 37 0.025
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 37 0.025
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 37 0.025
>gi|88703041 sorting nexin 6 isoform b [Homo sapiens]
Length = 418
Score = 825 bits (2132), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MRACAGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKF 60
MRACAGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKF
Sbjct: 1 MRACAGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKF 60
Query: 61 TVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQ 120
TVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQ
Sbjct: 61 TVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQ 120
Query: 121 KLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLE 180
KLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLE
Sbjct: 121 KLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLE 180
Query: 181 YNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDAS 240
YNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDAS
Sbjct: 181 YNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDAS 240
Query: 241 AKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADE 300
AKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADE
Sbjct: 241 AKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADE 300
Query: 301 DLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCC 360
DLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCC
Sbjct: 301 DLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCC 360
Query: 361 QKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT 418
QKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT
Sbjct: 361 QKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT 418
>gi|88703043 sorting nexin 6 isoform a [Homo sapiens]
Length = 290
Score = 568 bits (1464), Expect = e-162
Identities = 290/290 (100%), Positives = 290/290 (100%)
Query: 129 MTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVR 188
MTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVR
Sbjct: 1 MTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVR 60
Query: 189 GKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTR 248
GKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTR
Sbjct: 61 GKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTR 120
Query: 249 SHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLL 308
SHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLL
Sbjct: 121 SHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLL 180
Query: 309 KYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISE 368
KYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISE
Sbjct: 181 KYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISE 240
Query: 369 SAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT 418
SAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT
Sbjct: 241 SAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT 290
>gi|72534838 sorting nexin 6B [Homo sapiens]
Length = 403
Score = 555 bits (1431), Expect = e-158
Identities = 272/386 (70%), Positives = 333/386 (86%), Gaps = 3/386 (0%)
Query: 35 NVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVE 94
+VDLQ D++LQV+ISDA+SERDKVKFTV TKS LP+F Q EFSVVRQHEEFIWLHD++VE
Sbjct: 17 SVDLQGDSSLQVEISDAVSERDKVKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVE 76
Query: 95 NEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVA 154
NE+YAG IIPPAPPRPDF+ASREKLQKLGEG+ S+T+EEF KMKQELEAEYLAIFKKTVA
Sbjct: 77 NEEYAGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVA 136
Query: 155 MHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIV-- 212
MHEVFL R+AAHP LRRD NF VFLEY QDLSVRGKN+KE L F +N+VKSAD ++
Sbjct: 137 MHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITG 196
Query: 213 -SGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQD 271
SG+K+VDDFFEHERTFLLEYH R++DA ++DR+ R+HK ADDY I ++L +LGTQ+
Sbjct: 197 MSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQE 256
Query: 272 STDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVD 331
+ FLK++ELF++ RK+E RV++DEDLKLSD+L+YY+R+SQAAKDLLYRR R+L D
Sbjct: 257 VNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALAD 316
Query: 332 YENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVE 391
YENANKALDKAR +N++V AE+ QQLCCQ+FE++S+SAKQEL+DFK+RRV++FRKNL+E
Sbjct: 317 YENANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIE 376
Query: 392 LAELELKHAKGNLQLLQNCLAVLNGD 417
LAELELKHAK + +L+N L L G+
Sbjct: 377 LAELELKHAKASTLILRNTLVALKGE 402
>gi|23111047 sorting nexin 5 [Homo sapiens]
Length = 404
Score = 536 bits (1382), Expect = e-152
Identities = 256/387 (66%), Positives = 326/387 (84%), Gaps = 1/387 (0%)
Query: 26 EEDRG-LKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEE 84
EEDR L++++VDL D +LQ+DI DALSERDKVKFTVHTK++LP F+ EFSV RQHE+
Sbjct: 12 EEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSVTRQHED 71
Query: 85 FIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAE 144
F+WLHD+ +E DYAG IIPPAP +PDFD REK+QKLGEGEGSMTKEEF KMKQELEAE
Sbjct: 72 FVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAE 131
Query: 145 YLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMV 204
YLA+FKKTV+ HEVFL R+++HP+L +D NFHVFLEY+QDLSVR KN KE FFK++V
Sbjct: 132 YLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVV 191
Query: 205 KSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSL 264
KSAD V+ +GVK+VDDFFE E+ FL+ Y+NR+KD+ K+D+MTRSHK+ ADDY + L
Sbjct: 192 KSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACL 251
Query: 265 YALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYR 324
++L ++ T I K+ LKV+ELF+K RK+E RVS+DEDLKL++LL+YY+ +AAKDLLYR
Sbjct: 252 HSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYR 311
Query: 325 RSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAA 384
R+++L+DYEN+NKALDKAR K+KDV AE QQ CCQKFE++SESAK+ELI+FK +RVAA
Sbjct: 312 RTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAA 371
Query: 385 FRKNLVELAELELKHAKGNLQLLQNCL 411
FRKNL+E++ELE+KHA+ N+ LLQ+C+
Sbjct: 372 FRKNLIEMSELEIKHARNNVSLLQSCI 398
>gi|7657599 sorting nexin 5 [Homo sapiens]
Length = 404
Score = 536 bits (1382), Expect = e-152
Identities = 256/387 (66%), Positives = 326/387 (84%), Gaps = 1/387 (0%)
Query: 26 EEDRG-LKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEE 84
EEDR L++++VDL D +LQ+DI DALSERDKVKFTVHTK++LP F+ EFSV RQHE+
Sbjct: 12 EEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSVTRQHED 71
Query: 85 FIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAE 144
F+WLHD+ +E DYAG IIPPAP +PDFD REK+QKLGEGEGSMTKEEF KMKQELEAE
Sbjct: 72 FVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAE 131
Query: 145 YLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMV 204
YLA+FKKTV+ HEVFL R+++HP+L +D NFHVFLEY+QDLSVR KN KE FFK++V
Sbjct: 132 YLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVV 191
Query: 205 KSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSL 264
KSAD V+ +GVK+VDDFFE E+ FL+ Y+NR+KD+ K+D+MTRSHK+ ADDY + L
Sbjct: 192 KSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACL 251
Query: 265 YALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYR 324
++L ++ T I K+ LKV+ELF+K RK+E RVS+DEDLKL++LL+YY+ +AAKDLLYR
Sbjct: 252 HSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYR 311
Query: 325 RSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAA 384
R+++L+DYEN+NKALDKAR K+KDV AE QQ CCQKFE++SESAK+ELI+FK +RVAA
Sbjct: 312 RTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAA 371
Query: 385 FRKNLVELAELELKHAKGNLQLLQNCL 411
FRKNL+E++ELE+KHA+ N+ LLQ+C+
Sbjct: 372 FRKNLIEMSELEIKHARNNVSLLQSCI 398
>gi|23111038 sorting nexin 2 [Homo sapiens]
Length = 519
Score = 85.9 bits (211), Expect = 6e-17
Identities = 89/394 (22%), Positives = 165/394 (41%), Gaps = 50/394 (12%)
Query: 28 DRGLKAINVDLQSDAALQVDISDALSERDKV--------KFTVHTKSSLPNFKQNEFSVV 79
DR + I + D DI +S+ +KV + V TK+SL F ++EFSV
Sbjct: 125 DRSREEIEEEANGDI---FDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVK 181
Query: 80 RQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQ 139
R+ +F+ LH + GYI+PPAP + ++ K+ K E S + E K +
Sbjct: 182 RRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGK----EDSSSTEFVEKRRA 237
Query: 140 ELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDF 199
LE +L R HP L +D + FLE + +L +
Sbjct: 238 ALER---------------YLQRTVKHPTLLQDPDLRQFLE-SSELPRAVNTQALSGAGI 281
Query: 200 FKNMVKSADGVIVSGVK--DVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDY 257
+ + K+AD V +K + D +FE ++ +++ + + K + +
Sbjct: 282 LRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANT 341
Query: 258 NRIGSSLYALG-TQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQ 316
S LG ++D T + + +++E+ +K ++ + + S+LL Y+R
Sbjct: 342 AAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIA 401
Query: 317 AAKDLLYRRSRSLVDYENANKAL----------------DKARAKNKDVLQAETSQQLCC 360
A K + R + +E+A L DK + ++ + E Q
Sbjct: 402 AVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGE 461
Query: 361 QKFEKISESAKQELIDFKTRRVAAFRKNLVELAE 394
+ FE+IS++ ++E+ F+ RV F+ +++ E
Sbjct: 462 RDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLE 495
>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
Length = 522
Score = 84.0 bits (206), Expect = 2e-16
Identities = 81/377 (21%), Positives = 164/377 (43%), Gaps = 47/377 (12%)
Query: 45 QVDISDALSERDK--------VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENE 96
Q D++ +++ +K V + V T++SLP F+ +F+V R+ +F+ L++ E
Sbjct: 142 QFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKH 201
Query: 97 DYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMH 156
G+I+PP P + ++ K+ K E S + E K + LE
Sbjct: 202 SQNGFIVPPPPEKSLIGMTKVKVGK----EDSSSAEFLEKRRAALER------------- 244
Query: 157 EVFLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVK 216
+L R+ HP + +D + FLE ++L + K K+ D V +K
Sbjct: 245 --YLQRIVNHPTMLQDPDVREFLE-KEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIK 301
Query: 217 --DVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALG-TQDST 273
+ D +FE + + R++ A + + K A + + SL LG ++D+T
Sbjct: 302 MNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNT 361
Query: 274 DICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYE 333
+ + +++E+ +K ++ + ++ L++LL Y+R + +R ++ ++
Sbjct: 362 ALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQ 421
Query: 334 NANKALDKARAKNKDVLQAETSQQLCCQK----------------FEKISESAKQELIDF 377
+A L K R +L A +L K FE+IS ++E+I F
Sbjct: 422 DAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRF 481
Query: 378 KTRRVAAFRKNLVELAE 394
+ + F+ ++++ E
Sbjct: 482 EKEKSKDFKNHVIKYLE 498
>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
Length = 457
Score = 83.6 bits (205), Expect = 3e-16
Identities = 78/356 (21%), Positives = 155/356 (43%), Gaps = 39/356 (10%)
Query: 58 VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASRE 117
V + V T++SLP F+ +F+V R+ +F+ L++ E G+I+PP P + ++
Sbjct: 98 VAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKV 157
Query: 118 KLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHV 177
K+ K E S + E K + LE +L R+ HP + +D +
Sbjct: 158 KVGK----EDSSSAEFLEKRRAALER---------------YLQRIVNHPTMLQDPDVRE 198
Query: 178 FLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVK--DVDDFFEHERTFLLEYHNR 235
FLE ++L + K K+ D V +K + D +FE + + R
Sbjct: 199 FLE-KEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQR 257
Query: 236 VKDASAKSDRMTRSHKSAADDYNRIGSSLYALG-TQDSTDICKFFLKVSELFDKTRKIEA 294
++ A + + K A + + SL LG ++D+T + + +++E+ +K ++
Sbjct: 258 LRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQ 317
Query: 295 RVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAET 354
+ ++ L++LL Y+R + +R ++ +++A L K R +L A
Sbjct: 318 EQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANK 377
Query: 355 SQQLCCQK----------------FEKISESAKQELIDFKTRRVAAFRKNLVELAE 394
+L K FE+IS ++E+I F+ + F+ ++++ E
Sbjct: 378 PDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLE 433
>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
Length = 474
Score = 71.2 bits (173), Expect = 2e-12
Identities = 79/361 (21%), Positives = 158/361 (43%), Gaps = 63/361 (17%)
Query: 45 QVDISDALSERDK--------VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENE 96
Q D++ +++ +K V + V T++SLP F+ +F+V R+ +F+ L++ E
Sbjct: 142 QFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKH 201
Query: 97 DYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMH 156
G+I+PP P + ++ K+ K E S + E K + LE
Sbjct: 202 SQNGFIVPPPPEKSLIGMTKVKVGK----EDSSSAEFLEKRRAALER------------- 244
Query: 157 EVFLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVK 216
+L R+ HP + +D + FLE ++L + K K+ D V +K
Sbjct: 245 --YLQRIVNHPTMLQDPDVREFLE-KEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIK 301
Query: 217 --DVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALG-TQDST 273
+ D +FE + + R++ A + + K A + + SL LG ++D+T
Sbjct: 302 MNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNT 361
Query: 274 DICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYE 333
+ + +++E+ +K ++ + ++ L++LL Y+R LL ++V +E
Sbjct: 362 ALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIR-------LL-----AIVRWE 409
Query: 334 NANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELA 393
+ V Q E + FE+IS ++E+I F+ + F+ ++++
Sbjct: 410 SR-------------VTQYE-------RDFERISTVVRKEVIRFEKEKSKDFKNHVIKYL 449
Query: 394 E 394
E
Sbjct: 450 E 450
>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
Length = 451
Score = 52.8 bits (125), Expect = 6e-07
Identities = 76/356 (21%), Positives = 145/356 (40%), Gaps = 41/356 (11%)
Query: 58 VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASRE 117
+ + + TK+S F +EF V R++++F+WL E + IIPP P E
Sbjct: 114 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKL--EEAHPTLIIPPLP---------E 162
Query: 118 KLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHV 177
K + +G ++F + +++ A+H+ FL R+A HP L + +F +
Sbjct: 163 KF--IVKGMVERFNDDFIETRRK-------------ALHK-FLNRIADHPTLTFNEDFKI 206
Query: 178 FLEYNQ-DLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRV 236
FL +LS K L + + A + GVK+ + F F+ + ++
Sbjct: 207 FLTAQAWELSSHKKQGPGLLSRMGQTVRAVASS--MRGVKNRPEEFMEMNNFIELFSQKI 264
Query: 237 KDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARV 296
S R+ + + D+ G ++ L + D+ V+ D+ K +
Sbjct: 265 NLIDKISQRIYKEEREYFDEMKEYG-PIHILWSASEEDLVDTLKDVASCIDRCCKATEKR 323
Query: 297 SADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQ 356
+ L ++ Y+ S+ ++ RR + + ++ + L +A + D+L E
Sbjct: 324 MSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKA-DTDLLPEEIG- 381
Query: 357 QLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLA 412
K E E A L R +N ++LA ++ A+ N+ + CLA
Sbjct: 382 -----KLEDKVECANNAL-KADWERWKQNMQNDIKLAFTDM--AEENIHYYEQCLA 429
>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
Length = 336
Score = 50.1 bits (118), Expect = 4e-06
Identities = 59/288 (20%), Positives = 118/288 (40%), Gaps = 31/288 (10%)
Query: 58 VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASRE 117
+ + + TK+S F +EF V R++++F+WL E + IIPP P E
Sbjct: 50 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKL--EEAHPTLIIPPLP---------E 98
Query: 118 KLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHV 177
K + +G ++F + +++ A+H+ FL R+A HP L + +F +
Sbjct: 99 KF--IVKGMVERFNDDFIETRRK-------------ALHK-FLNRIADHPTLTFNEDFKI 142
Query: 178 FLEYNQ-DLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRV 236
FL +LS K L + + A + GVK+ + F F+ + ++
Sbjct: 143 FLTAQAWELSSHKKQGPGLLSRMGQTVRAVASS--MRGVKNRPEEFMEMNNFIELFSQKI 200
Query: 237 KDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARV 296
S R+ + + D+ G ++ L + D+ V+ D+ K +
Sbjct: 201 NLIDKISQRIYKEEREYFDEMKEYG-PIHILWSASEEDLVDTLKDVASCIDRCCKATEKR 259
Query: 297 SADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARA 344
+ L ++ Y+ S+ ++ RR + + ++ + L +A
Sbjct: 260 MSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKA 307
>gi|153791707 sorting nexin family member 30 [Homo sapiens]
Length = 437
Score = 44.3 bits (103), Expect = 2e-04
Identities = 69/354 (19%), Positives = 144/354 (40%), Gaps = 42/354 (11%)
Query: 58 VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASRE 117
+ + + TKS+ F E+SV R++++F WL E++ ++IPP P E
Sbjct: 109 ITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQ--PTHLIPPLP---------E 157
Query: 118 KLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHV 177
K + +G EEF + +++ A+ K FL R+ HP+L + +F++
Sbjct: 158 KF--VVKGVVDRFSEEFVETRRK------ALDK--------FLKRITDHPVLSFNEHFNI 201
Query: 178 FLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVK 237
FL +DL+ K L ++ VK G + ++ F +L + ++
Sbjct: 202 FLT-AKDLNAYKKQGIALLTRMGES-VKHVTGGYKLRTRPLE--FAAIGDYLDTFALKLG 257
Query: 238 DASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVS 297
+ R+ + + G +Y+ + ++ + VS ++
Sbjct: 258 TIDRIAQRIIKEEIEYLVELREYG-PVYSTWSALEGELAEPLEGVSACIGNCSTALEELT 316
Query: 298 ADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQ 357
D +L+ Y+ S + K +L +R + +YE L+ + +D + +
Sbjct: 317 DDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYE---AKLEAVALRKEDRPKVPADVE 373
Query: 358 LCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCL 411
C + E + K ++ ++ + FR+ L+ +A+ N+Q + CL
Sbjct: 374 KCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMAD-------KNIQYYEKCL 420
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 43.5 bits (101), Expect = 4e-04
Identities = 30/130 (23%), Positives = 62/130 (47%), Gaps = 9/130 (6%)
Query: 176 HVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIV--SGVKDVDDFFEHERTFLLEYH 233
H+ L +K+ +++ + + K+ D + S K D F++ +T +++
Sbjct: 771 HIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFE 830
Query: 234 NRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIE 293
+ K +++RM + + + + + SSL AL T+ S K EL +KTR+++
Sbjct: 831 QKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELS-------YKTQELQEKTREVQ 883
Query: 294 ARVSADEDLK 303
R++ E LK
Sbjct: 884 ERLNEMEQLK 893
>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
Length = 653
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 4/98 (4%)
Query: 308 LKYYLRESQAAKDLLYRRSRSLVDYENANKALDKAR-AKNKD---VLQAETSQQLCCQKF 363
L YL + K+ + +RSR LVDY++A L+ + +K KD + +AE Q + F
Sbjct: 121 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF 180
Query: 364 EKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAK 401
E+ + ++EL +RRV + ++ LE K K
Sbjct: 181 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHK 218
>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
Length = 695
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 4/98 (4%)
Query: 308 LKYYLRESQAAKDLLYRRSRSLVDYENANKALDKAR-AKNKD---VLQAETSQQLCCQKF 363
L YL + K+ + +RSR LVDY++A L+ + +K KD + +AE Q + F
Sbjct: 121 LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF 180
Query: 364 EKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAK 401
E+ + ++EL +RRV + ++ LE K K
Sbjct: 181 EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHK 218
>gi|4507143 sorting nexin 3 isoform a [Homo sapiens]
Length = 162
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 27/141 (19%)
Query: 44 LQVDISD----ALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYA 99
L++D+S+ + + + K++LP FK E +V R++ +F WL E E +
Sbjct: 29 LEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRS---ELERES 85
Query: 100 GYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVF 159
++PP P + A +L G+ +G + KQ LE F
Sbjct: 86 KVVVPPLPGK----AFLRQLPFRGD-DGIFDDNFIEERKQGLEQ---------------F 125
Query: 160 LCRVAAHPILRRDLNFHVFLE 180
+ +VA HP+ + + H+FL+
Sbjct: 126 INKVAGHPLAQNERCLHMFLQ 146
>gi|23111030 sorting nexin 12 [Homo sapiens]
Length = 162
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 23/121 (19%)
Query: 60 FTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKL 119
+ V +++LP FK E V R++ +F WL + E E + ++PP P + A + +L
Sbjct: 50 YEVRMRTNLPIFKLKESCVRRRYSDFEWLKN---ELERDSKIVVPPLPGK----ALKRQL 102
Query: 120 QKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFL 179
G+ EG + + +Q LE F+ ++A HP+ + + H+FL
Sbjct: 103 PFRGD-EGIFEESFIEERRQGLEQ---------------FINKIAGHPLAQNERCLHMFL 146
Query: 180 E 180
+
Sbjct: 147 Q 147
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 39.3 bits (90), Expect = 0.007
Identities = 35/151 (23%), Positives = 67/151 (44%), Gaps = 13/151 (8%)
Query: 274 DICKFFLKVSELFDKTRK---IEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLV 330
D K K E+ D T K + ++++K DL+ + + KD++ S +
Sbjct: 1267 DKIKTLEKNQEILDDTAKNLRVMLESEREQNVKNQDLISENKKSIEKLKDVI---SMNAS 1323
Query: 331 DYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFK------TRRVAA 384
++ AL++A+ + V Q + +K E +QE+ D+ + ++ +
Sbjct: 1324 EFSEVQIALNEAKLSEEKVKSECHRVQEENARLKKKKEQLQQEIEDWSKLHAELSEQIKS 1383
Query: 385 FRKNLVELAELELKHAKGNLQLLQNCLAVLN 415
F K+ +L E+ L H N+ L NC+ LN
Sbjct: 1384 FEKSQKDL-EVALTHKDDNINALTNCITQLN 1413
>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
Length = 409
Score = 38.1 bits (87), Expect = 0.015
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 311 YLRESQAAKDLLYRRSRSLVDYENAN---KALDKARAKNKDVLQAETSQQLCCQK-FEKI 366
YL + K + +R R LVDY++A ++L A+ K++ + + + QK FE++
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 367 SESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNG 416
+ ++EL RV + +A LE K +L QN VL G
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVG 238
>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
Length = 439
Score = 38.1 bits (87), Expect = 0.015
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 311 YLRESQAAKDLLYRRSRSLVDYENAN---KALDKARAKNKDVLQAETSQQLCCQK-FEKI 366
YL + K + +R R LVDY++A ++L A+ K++ + + + QK FE++
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 367 SESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNG 416
+ ++EL RV + +A LE K +L QN VL G
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVG 238
>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
Length = 475
Score = 38.1 bits (87), Expect = 0.015
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 311 YLRESQAAKDLLYRRSRSLVDYENAN---KALDKARAKNKDVLQAETSQQLCCQK-FEKI 366
YL + K + +R R LVDY++A ++L A+ K++ + + + QK FE++
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 367 SESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNG 416
+ ++EL RV + +A LE K +L QN VL G
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVG 238
>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
Length = 482
Score = 38.1 bits (87), Expect = 0.015
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 311 YLRESQAAKDLLYRRSRSLVDYENAN---KALDKARAKNKDVLQAETSQQLCCQK-FEKI 366
YL + K + +R R LVDY++A ++L A+ K++ + + + QK FE++
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 367 SESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNG 416
+ ++EL RV + +A LE K +L QN VL G
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVG 238
>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
Length = 518
Score = 38.1 bits (87), Expect = 0.015
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 311 YLRESQAAKDLLYRRSRSLVDYENAN---KALDKARAKNKDVLQAETSQQLCCQK-FEKI 366
YL + K + +R R LVDY++A ++L A+ K++ + + + QK FE++
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 367 SESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNG 416
+ ++EL RV + +A LE K +L QN VL G
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVG 238
>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
Length = 497
Score = 38.1 bits (87), Expect = 0.015
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 311 YLRESQAAKDLLYRRSRSLVDYENAN---KALDKARAKNKDVLQAETSQQLCCQK-FEKI 366
YL + K + +R R LVDY++A ++L A+ K++ + + + QK FE++
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 367 SESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNG 416
+ ++EL RV + +A LE K +L QN VL G
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVG 238
>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
Length = 454
Score = 38.1 bits (87), Expect = 0.015
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 311 YLRESQAAKDLLYRRSRSLVDYENAN---KALDKARAKNKDVLQAETSQQLCCQK-FEKI 366
YL + K + +R R LVDY++A ++L A+ K++ + + + QK FE++
Sbjct: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
Query: 367 SESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNG 416
+ ++EL RV + +A LE K +L QN VL G
Sbjct: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVG 238
>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
Length = 1711
Score = 37.7 bits (86), Expect = 0.020
Identities = 59/279 (21%), Positives = 125/279 (44%), Gaps = 40/279 (14%)
Query: 118 KLQKLGEGEGSMTK--EEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNF 175
K+++ G G G+ + +E +K+K ELE KK + E + R A+H + +++
Sbjct: 665 KVKQGGRGAGATLEHQQEISKIKSELE-------KKVLFYEEELVRREASHVLEVKNVKK 717
Query: 176 HVFLEYNQDLSVRG-----KNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLL 230
V + L+++ K+K EK + N ++ A G I D +E ER L
Sbjct: 718 EVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTI-------KDKYERERAMLF 770
Query: 231 EYHNRVKDASAK----SDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELF 286
+ + ++ + K D++T ++ D+ + + ++ ++ I + VS+
Sbjct: 771 DENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEA-QIAEIIQWVSDEK 829
Query: 287 DKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDL----LYRRSRSL-----VDYENANK 337
D ++A S K+++ L+ S ++ L RRS+ L ++ ++A +
Sbjct: 830 DARGYLQALAS-----KMTEELEALRSSSLGSRTLDPLWKVRRSQKLDMSARLELQSALE 884
Query: 338 ALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELID 376
A +A+ ++ L+ L + K SE+ +EL++
Sbjct: 885 AEIRAKQLVQEELRKVKDANLTLESKLKDSEAKNRELLE 923
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 37.4 bits (85), Expect = 0.025
Identities = 62/332 (18%), Positives = 138/332 (41%), Gaps = 39/332 (11%)
Query: 111 DFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILR 170
+ + R +L L E S + ++ +E +++Y K+ +++ + + + +
Sbjct: 461 ELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMD 520
Query: 171 RDLNFHVFLEYNQDLSV----------RGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDD 220
+FH ++++V + KEK+ + + +V+ G ++ V++
Sbjct: 521 NYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIK--PPVEE 578
Query: 221 FFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTD------ 274
+ E + ++ N K+ + + ++ A ++ ++ +L + TQ+++D
Sbjct: 579 YEEMKSSYCSVIENMNKEKAF----LFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMK 634
Query: 275 ------ICKFFLKVSELFDKTRKIEARVSADEDLK-LSDLLKYYLRESQAAKDLLYRRSR 327
I + +VSEL ++ +A + K L D+ Y+ +++ K +
Sbjct: 635 EAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLM----QL 690
Query: 328 SLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFR- 386
+ V A AL + +++ VL T + ++ S S + L T R AA
Sbjct: 691 TNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEM 750
Query: 387 ----KNLVE-LAELELKHAKGNLQLLQNCLAV 413
NL E LA E++ AK QLL+ A+
Sbjct: 751 EEKISNLKEHLASKEVEVAKLEKQLLEEKAAM 782
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 37.4 bits (85), Expect = 0.025
Identities = 62/332 (18%), Positives = 138/332 (41%), Gaps = 39/332 (11%)
Query: 111 DFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILR 170
+ + R +L L E S + ++ +E +++Y K+ +++ + + + +
Sbjct: 450 ELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMD 509
Query: 171 RDLNFHVFLEYNQDLSV----------RGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDD 220
+FH ++++V + KEK+ + + +V+ G ++ V++
Sbjct: 510 NYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIK--PPVEE 567
Query: 221 FFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTD------ 274
+ E + ++ N K+ + + ++ A ++ ++ +L + TQ+++D
Sbjct: 568 YEEMKSSYCSVIENMNKEKAF----LFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMK 623
Query: 275 ------ICKFFLKVSELFDKTRKIEARVSADEDLK-LSDLLKYYLRESQAAKDLLYRRSR 327
I + +VSEL ++ +A + K L D+ Y+ +++ K +
Sbjct: 624 EAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLM----QL 679
Query: 328 SLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFR- 386
+ V A AL + +++ VL T + ++ S S + L T R AA
Sbjct: 680 TNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEM 739
Query: 387 ----KNLVE-LAELELKHAKGNLQLLQNCLAV 413
NL E LA E++ AK QLL+ A+
Sbjct: 740 EEKISNLKEHLASKEVEVAKLEKQLLEEKAAM 771
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 37.4 bits (85), Expect = 0.025
Identities = 62/332 (18%), Positives = 138/332 (41%), Gaps = 39/332 (11%)
Query: 111 DFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILR 170
+ + R +L L E S + ++ +E +++Y K+ +++ + + + +
Sbjct: 429 ELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMD 488
Query: 171 RDLNFHVFLEYNQDLSV----------RGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDD 220
+FH ++++V + KEK+ + + +V+ G ++ V++
Sbjct: 489 NYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIK--PPVEE 546
Query: 221 FFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTD------ 274
+ E + ++ N K+ + + ++ A ++ ++ +L + TQ+++D
Sbjct: 547 YEEMKSSYCSVIENMNKEKAF----LFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMK 602
Query: 275 ------ICKFFLKVSELFDKTRKIEARVSADEDLK-LSDLLKYYLRESQAAKDLLYRRSR 327
I + +VSEL ++ +A + K L D+ Y+ +++ K +
Sbjct: 603 EAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLM----QL 658
Query: 328 SLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFR- 386
+ V A AL + +++ VL T + ++ S S + L T R AA
Sbjct: 659 TNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEM 718
Query: 387 ----KNLVE-LAELELKHAKGNLQLLQNCLAV 413
NL E LA E++ AK QLL+ A+
Sbjct: 719 EEKISNLKEHLASKEVEVAKLEKQLLEEKAAM 750
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 37.4 bits (85), Expect = 0.025
Identities = 62/332 (18%), Positives = 138/332 (41%), Gaps = 39/332 (11%)
Query: 111 DFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILR 170
+ + R +L L E S + ++ +E +++Y K+ +++ + + + +
Sbjct: 458 ELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMD 517
Query: 171 RDLNFHVFLEYNQDLSV----------RGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDD 220
+FH ++++V + KEK+ + + +V+ G ++ V++
Sbjct: 518 NYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIK--PPVEE 575
Query: 221 FFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTD------ 274
+ E + ++ N K+ + + ++ A ++ ++ +L + TQ+++D
Sbjct: 576 YEEMKSSYCSVIENMNKEKAF----LFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMK 631
Query: 275 ------ICKFFLKVSELFDKTRKIEARVSADEDLK-LSDLLKYYLRESQAAKDLLYRRSR 327
I + +VSEL ++ +A + K L D+ Y+ +++ K +
Sbjct: 632 EAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLM----QL 687
Query: 328 SLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFR- 386
+ V A AL + +++ VL T + ++ S S + L T R AA
Sbjct: 688 TNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEM 747
Query: 387 ----KNLVE-LAELELKHAKGNLQLLQNCLAV 413
NL E LA E++ AK QLL+ A+
Sbjct: 748 EEKISNLKEHLASKEVEVAKLEKQLLEEKAAM 779
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,118,605
Number of Sequences: 37866
Number of extensions: 583573
Number of successful extensions: 2452
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 81
Number of HSP's that attempted gapping in prelim test: 2394
Number of HSP's gapped (non-prelim): 132
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.