Search of human proteins with 83415174

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
         (942 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83415174 hypothetical protein LOC400818 [Homo sapiens]            1892   0.0  
gi|92110019 hypothetical protein LOC55672 [Homo sapiens]             1752   0.0  
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]        1721   0.0  
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ...  1713   0.0  
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho...  1318   0.0  
gi|156071420 hypothetical protein LOC728912 [Homo sapiens]           1317   0.0  
gi|157266285 hypothetical protein LOC728936 [Homo sapiens]           1288   0.0  
gi|29789405 hypothetical protein LOC284565 [Homo sapiens]            1283   0.0  
gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap...  1230   0.0  
gi|7657017 hypothetical protein LOC25832 [Homo sapiens]              1081   0.0  
gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi...   828   0.0  
gi|239741297 PREDICTED: neuroblastoma breakpoint family, member ...   525   e-149
gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1...   474   e-133
gi|114158664 hypothetical protein LOC343505 [Homo sapiens]            471   e-132
gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sap...   470   e-132
gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2...   469   e-132
gi|239758011 PREDICTED: hypothetical protein LOC728841, partial ...   225   2e-58
gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami...   119   2e-26
gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami...   116   1e-25
gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6...   116   1e-25
gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6...   113   7e-25
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    84   8e-16
gi|7657138 golgi integral membrane protein 4 [Homo sapiens]            74   6e-13
gi|148746195 trichohyalin [Homo sapiens]                               69   2e-11
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    64   5e-10
gi|150010604 kinesin family member 4B [Homo sapiens]                   64   7e-10
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         64   7e-10
gi|21735548 centrosomal protein 2 [Homo sapiens]                       63   1e-09
gi|71061468 centromere protein E [Homo sapiens]                        63   1e-09
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          61   4e-09

>gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
          Length = 942

 Score = 1892 bits (4901), Expect = 0.0
 Identities = 942/942 (100%), Positives = 942/942 (100%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL
Sbjct: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA
Sbjct: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300

Query: 301 EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
           EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA
Sbjct: 301 EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360

Query: 361 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 420
           EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 361 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 420

Query: 421 EGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
           EGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
Sbjct: 421 EGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480

Query: 481 TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEK 540
           TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEK
Sbjct: 481 TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEK 540

Query: 541 GPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG 600
           GPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG
Sbjct: 541 GPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG 600

Query: 601 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAF 660
           RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAF
Sbjct: 601 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAF 660

Query: 661 YVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSG 720
           YVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSG
Sbjct: 661 YVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSG 720

Query: 721 YPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780
           YPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE
Sbjct: 721 YPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780

Query: 781 VLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840
           VLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
Sbjct: 781 VLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840

Query: 841 SKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHY 900
           SKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHY
Sbjct: 841 SKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHY 900

Query: 901 RSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ 942
           RSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
Sbjct: 901 RSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ 942


>gi|92110019 hypothetical protein LOC55672 [Homo sapiens]
          Length = 1214

 Score = 1752 bits (4537), Expect = 0.0
 Identities = 884/943 (93%), Positives = 905/943 (95%), Gaps = 1/943 (0%)

Query: 1    MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
            MVVSAGP SSEKAEMNILE+NEKLRPQLAE KQQF NLKE+CF+TQLAGFLAN+Q KYKY
Sbjct: 272  MVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKY 331

Query: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
            EEC+DLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQL+EKLREGRDAS
Sbjct: 332  EECEDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 391

Query: 121  RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
            RSLN+HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEE E
Sbjct: 392  RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 451

Query: 181  KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
            KVLES APREVQKAEESKV EDSLEECAITCSNSHGPCDSNQPHKNI ITFEED+VNS L
Sbjct: 452  KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL 511

Query: 241  VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
            VVDRESSHDECQDA+NILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE+NEKLRPQLA
Sbjct: 512  VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLA 571

Query: 301  EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
            EKKQQFRNLKEKCF+TQLA FLANQQNKYKYEECKDLIK +LRNERQFKEEKLAEQLKQA
Sbjct: 572  EKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQA 631

Query: 361  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 420
            EELRQYKVLVH+QERELTQLREKLREGRDASRSLN+HLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 632  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLA 691

Query: 421  EGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
            EGCRLAQ L QKLSPENDND +EDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
Sbjct: 692  EGCRLAQQLFQKLSPENDNDHDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 751

Query: 481  TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEK 540
            T SNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE EDAVHIIPENESDDEEEEEK
Sbjct: 752  TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 811

Query: 541  GPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG 600
            GPVSPRNLQESEEEEVPQESWDEGYST SIPPEMLASY+SYS TFHSLEEQQVCMAVDIG
Sbjct: 812  GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDIG 871

Query: 601  RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAF 660
             HRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSL RCYSTPSG LELTDSCQPYRSAF
Sbjct: 872  GHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAF 931

Query: 661  YVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSG 720
            Y+LEQQRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSG
Sbjct: 932  YILEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 991

Query: 721  YPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780
            Y ELPDLGQPY SAVYSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLE VEPE
Sbjct: 992  YLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPE 1051

Query: 781  VLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840
            VLQDSLDRCYSTPSSCLEQPDS  PYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
Sbjct: 1052 VLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 1111

Query: 841  S-KKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQH 899
            S KK RRRGRKEGEEDQNPPCPRL+G+LMEVEEPEVLQDSLD CYSTPSMYFELPDSFQH
Sbjct: 1112 STKKRRRRGRKEGEEDQNPPCPRLSGMLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQH 1171

Query: 900  YRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ 942
            YRSVFYSFEEQHISFAL VDNRF TL  TSLHLVFQM VIFPQ
Sbjct: 1172 YRSVFYSFEEQHISFALDVDNRFLTLMGTSLHLVFQMGVIFPQ 1214



 Score = 1053 bits (2724), Expect = 0.0
 Identities = 610/993 (61%), Positives = 692/993 (69%), Gaps = 121/993 (12%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGPWSSEKAE NILEINEKLRPQLAENKQQF NLKE+CF+TQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
           RSLN+HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEE E
Sbjct: 121 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KVLES APREVQKAEESKV EDSLEECAITCSNSHGPCDSNQPHKNI ITFEED+VNSTL
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTL 240

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           VVDRESSHDECQDA+NILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE+NEKLRPQLA
Sbjct: 241 VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLA 300

Query: 301 EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
           EKKQQFRNLKEKCF+TQLAGFLANQQNKYKYEEC+DLIK MLRNERQFKEEKLAEQLKQA
Sbjct: 301 EKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECEDLIKSMLRNERQFKEEKLAEQLKQA 360

Query: 361 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 420
           EELRQYKVLVH+QERELTQLREKLREGRDASRSLN+HLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 361 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLA 420

Query: 421 EGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
           EGCRLAQHLVQKLSPEND D++EDVQVE AEKV +SSAPRE+QKAEE +VPEDSLEECAI
Sbjct: 421 EGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAI 480

Query: 481 TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHVEREDAVHIIP-----ENESD 533
           T SNSHGP DSNQPH+   ITFEEDKV+S L+    SSH E +DAV+I+P      + ++
Sbjct: 481 TCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATN 540

Query: 534 DEEEEEKGPVSPR----NLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLE 589
                  GP+S      N+ E  E+  PQ                LA  K     F +L+
Sbjct: 541 VSMVVSAGPLSSEKAEMNILEMNEKLRPQ----------------LAEKK---QQFRNLK 581

Query: 590 E-----QQVC-MAVDIGRHRWDQVK-------KEDQEATGPRLSRELLDEKGPEVLQDSL 636
           E     Q  C +A    ++++++ K       + +++    +L+ +L   K  E L+   
Sbjct: 582 EKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQL---KQAEELRQYK 638

Query: 637 YRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV------------------------ 672
              +S      +L +  +  R A   L Q    L                          
Sbjct: 639 VLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQ 698

Query: 673 ------------DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSG 720
                       D DE  + +  E+ Q  S P   RE+   +E EV +DSL     T S 
Sbjct: 699 QLFQKLSPENDNDHDEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLEECAITCSN 755

Query: 721 YPELPDLGQPYSSAVYSLEEQYLGLAL--------------DLDRIKKDQEEEEDQGPPC 766
                D  QP+     + EE  +   L               +   + D EEEE++GP  
Sbjct: 756 SHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVS 815

Query: 767 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGE 826
           P   R L E  E EV Q+S D  YST S   E   S+Q Y  +F++LEE+ V  ++D+G 
Sbjct: 816 P---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDIG- 871

Query: 827 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYST 886
                      G R  + ++       EDQ    PRL+  L++ + PEVLQDSLD CYST
Sbjct: 872 -----------GHRWDQVKK-------EDQEATGPRLSRELLDEKGPEVLQDSLDRCYST 913

Query: 887 PSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
           PS Y EL DS Q YRS FY  E+Q + +AL +D
Sbjct: 914 PSGYLELTDSCQPYRSAFYILEQQRVGWALDMD 946


>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
          Length = 3628

 Score = 1721 bits (4457), Expect = 0.0
 Identities = 866/919 (94%), Positives = 883/919 (96%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGPWSSEKAEMNILEINE LRPQLAE KQQF NLKE+CFLTQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
           RSL EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEE E
Sbjct: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KVLES APREVQKAEESKV EDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA
Sbjct: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300

Query: 301 EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
           EKKQQFRNLKEKCFLTQL+GFLANQQ KYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA
Sbjct: 301 EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360

Query: 361 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 420
           EELRQYKVLVHAQERELTQL+EKLREGRDASRSLNEHLQALLTP EPDKSQGQDLQEQLA
Sbjct: 361 EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420

Query: 421 EGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
           EGCRLAQHLVQKLSPENDNDD+EDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
Sbjct: 421 EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480

Query: 481 TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEK 540
           TYSNSHG YDSNQPHRKTKITFEEDKVDSTLIGSSSHVE EDAVHIIPENESDDEEEEEK
Sbjct: 481 TYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 540

Query: 541 GPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG 600
           GPVSPRNLQESEEEEVPQESWDEGYST SIPPEMLASY+SYSSTFHSLEEQQVCMAVDIG
Sbjct: 541 GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG 600

Query: 601 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAF 660
           RHRWDQVKKEDQEATGPRLSRELLDEKGPEV QDS  RCYSTPSGCLELTDSCQPYRSAF
Sbjct: 601 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAF 660

Query: 661 YVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSG 720
           Y+LEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSG
Sbjct: 661 YILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 720

Query: 721 YPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780
           Y ELPDLGQPYSSAVYSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPE
Sbjct: 721 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780

Query: 781 VLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840
           VLQDSLDRCYSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
Sbjct: 781 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840

Query: 841 SKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHY 900
           SKKERRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q Y
Sbjct: 841 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY 900

Query: 901 RSVFYSFEEQHISFALYVD 919
           RS FY  E+Q + FA+ +D
Sbjct: 901 RSAFYVLEQQRVGFAVDMD 919



 Score = 1014 bits (2622), Expect = 0.0
 Identities = 583/954 (61%), Positives = 659/954 (69%), Gaps = 97/954 (10%)

Query: 1    MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
            MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQF NLKE+CFLTQL+GFLAN+QKKYKY
Sbjct: 272  MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKY 331

Query: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
            EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLKEKLREGRDAS
Sbjct: 332  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDAS 391

Query: 121  RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
            RSLNEHLQALLTP EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE  E
Sbjct: 392  RSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 451

Query: 181  KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
            KV +S APRE+QKAEE +V EDSLEECAIT SNSHG  DSNQPH+  KITFEED+V+STL
Sbjct: 452  KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511

Query: 241  VVDRESSHDECQDALNILPV----------PGPTSSATNVSMVVSAGPLSSEKAEMNILE 290
            +    SSH E +DA++I+P            GP S            P  S     + L 
Sbjct: 512  I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 569

Query: 291  INEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKE 350
            I  ++          F +L+E+         +A    ++++++ K             KE
Sbjct: 570  IPPEMLASYQSYSSTFHSLEEQQVC------MAVDIGRHRWDQVK-------------KE 610

Query: 351  EKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKS 410
            ++ A   + + EL   K              E  ++ +D   S       L    +P +S
Sbjct: 611  DQEATGPRLSRELLDEKG------------PEVFQDSQDRCYSTPSGCLELTDSCQPYRS 658

Query: 411  QGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEE 467
                L++Q             ++    D D+ E  Q    E+ Q  S PR   E+   +E
Sbjct: 659  AFYILEQQ-------------RVGLAIDMDEIEKYQE--VEEDQDPSCPRLSRELLDEKE 703

Query: 468  KEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHII 527
             EV +DSL+ C  T S      D  QP+     + EE       +G +  V+R       
Sbjct: 704  PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALDVDRI------ 752

Query: 528  PENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSST 584
               + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E   S + Y S+
Sbjct: 753  ---KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 809

Query: 585  FHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGPRLSRELLD 625
            F++LEE+ V  ++D+G                   R R  +  +EDQ    PRLSRELLD
Sbjct: 810  FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLD 869

Query: 626  EKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEE 685
            EKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG AVDMDEIEKYQEVEE
Sbjct: 870  EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEE 929

Query: 686  DQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGL 745
            DQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYSLEEQYLGL
Sbjct: 930  DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 989

Query: 746  ALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQP 805
            ALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QP
Sbjct: 990  ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 1049

Query: 806  YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNG 865
            YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+ 
Sbjct: 1050 YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 1109

Query: 866  VLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
             L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+Q + FA+ +D
Sbjct: 1110 ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMD 1163



 Score =  620 bits (1598), Expect = e-177
 Identities = 399/795 (50%), Positives = 469/795 (58%), Gaps = 86/795 (10%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL  C  T S      
Sbjct: 1398 QRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELP 1457

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDR-----ESSHDECQDALNILPVPGPTSSATNVSMV 273
            D  QP+ +   + EE  +   L VDR     E   DE QD     P P            
Sbjct: 1458 DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDP----PCPR----------- 1502

Query: 274  VSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYE- 332
                 LS E  E+   E+ +    +            + C     + F A ++N   +  
Sbjct: 1503 -----LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEENHVGFSL 1556

Query: 333  ---ECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRD 389
               E +   K   R  R+ K+E+   + K+ EE +       ++E    +  E L++  D
Sbjct: 1557 DVGEIEKKGKGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLD 1615

Query: 390  ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEV 449
               S       L    +P +S    L++Q              +    D D+ E  Q   
Sbjct: 1616 RCYSTPSGCLELTDSCQPYRSAFYVLEQQ-------------HVGLAVDMDEIEKYQE-- 1660

Query: 450  AEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDK 506
             E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE  
Sbjct: 1661 VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ- 1719

Query: 507  VDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDE 563
                 +G +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D 
Sbjct: 1720 ----YLGLALDVDRI---------KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDR 1766

Query: 564  GYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRW 604
             YSTPS   E   S + Y S+F++LEE  V  ++D+G                   R R 
Sbjct: 1767 CYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRG 1826

Query: 605  DQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLE 664
             +  +EDQ    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLE
Sbjct: 1827 RKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 1886

Query: 665  QQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPEL 724
            QQ VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY EL
Sbjct: 1887 QQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 1946

Query: 725  PDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 784
            PDLGQPYSSAVYSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD
Sbjct: 1947 PDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 2006

Query: 785  SLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 844
            SLDRCYSTPSSCLEQPDS QPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKE
Sbjct: 2007 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKE 2066

Query: 845  RRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVF 904
            RRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS F
Sbjct: 2067 RRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF 2126

Query: 905  YSFEEQHISFALYVD 919
            Y  E+QH+  A+ +D
Sbjct: 2127 YVLEQQHVGLAVDMD 2141



 Score =  619 bits (1595), Expect = e-177
 Identities = 396/784 (50%), Positives = 468/784 (59%), Gaps = 80/784 (10%)

Query: 167  DEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198

Query: 226  NIKITFEEDEVNSTLVVDR-ESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKA 284
            +   + EE  +   L VDR +   +E +D        GP               LS E  
Sbjct: 2199 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQ-------GPPCPR-----------LSRELL 2240

Query: 285  EMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYE----ECKDLIKF 340
            E+   E+ +    +            + C     + F A ++N   +     E +   K 
Sbjct: 2241 EVVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEENHVGFSLDVGEIEKKGKG 2299

Query: 341  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 400
              R  R+ K+E+   + K+ EE +       ++E    +  E L++  D   S       
Sbjct: 2300 KKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 2358

Query: 401  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR 460
            L    +P +S    L++Q              +    D D+ E  Q    E+ Q  S PR
Sbjct: 2359 LTDSCQPYRSAFYVLEQQ-------------HVGLAVDMDEIEKYQE--VEEDQDPSCPR 2403

Query: 461  ---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSH 517
               E+   +E EV +DSL+ C  T S      D  QP+     + EE       +G +  
Sbjct: 2404 LSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALD 2458

Query: 518  VEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEM 574
            V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E 
Sbjct: 2459 VDRI---------KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 2509

Query: 575  LASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEAT 615
              S + Y S+F++LEE  V  ++D+G                   R R  +  +EDQ   
Sbjct: 2510 PDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 2569

Query: 616  GPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675
             PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMD
Sbjct: 2570 CPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMD 2629

Query: 676  EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAV 735
            EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAV
Sbjct: 2630 EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 2689

Query: 736  YSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 795
            YSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS
Sbjct: 2690 YSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 2749

Query: 796  CLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 855
            CLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED
Sbjct: 2750 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 2809

Query: 856  QNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA 915
            QNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+QH+  A
Sbjct: 2810 QNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLA 2869

Query: 916  LYVD 919
            + +D
Sbjct: 2870 VDMD 2873



 Score =  617 bits (1590), Expect = e-176
 Identities = 395/784 (50%), Positives = 467/784 (59%), Gaps = 80/784 (10%)

Query: 167  DEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710

Query: 226  NIKITFEEDEVNSTLVVDR-ESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKA 284
            +   + EE  +   L VDR +   +E +D        GP               LS E  
Sbjct: 1711 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQ-------GPPCPR-----------LSRELL 1752

Query: 285  EMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYE----ECKDLIKF 340
            E+   E+ +    +            + C     + F A ++N   +     E +   K 
Sbjct: 1753 EVVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEENHVGFSLDVGEIEKKGKG 1811

Query: 341  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 400
              R  R+ K+E+   + K+ EE +       ++E    +  E L++  D   S       
Sbjct: 1812 KKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 1870

Query: 401  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR 460
            L    +P +S    L++Q              +    D D+ E  Q    E+ Q  S PR
Sbjct: 1871 LTDSCQPYRSAFYVLEQQ-------------HVGLAVDMDEIEKYQE--VEEDQDPSCPR 1915

Query: 461  ---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSH 517
               E+   +E EV +DSL+ C  T S      D  QP+     + EE       +G +  
Sbjct: 1916 LSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALD 1970

Query: 518  VEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEM 574
            V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E 
Sbjct: 1971 VDRI---------KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 2021

Query: 575  LASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEAT 615
              S + Y S+F++LEE  V  ++D+G                   R R  +  +EDQ   
Sbjct: 2022 PDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 2081

Query: 616  GPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675
             PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMD
Sbjct: 2082 CPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMD 2141

Query: 676  EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAV 735
            EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAV
Sbjct: 2142 EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 2201

Query: 736  YSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 795
            YSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS
Sbjct: 2202 YSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 2261

Query: 796  CLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 855
            CLEQPDS QPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED
Sbjct: 2262 CLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 2321

Query: 856  QNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA 915
            QNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+QH+  A
Sbjct: 2322 QNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLA 2381

Query: 916  LYVD 919
            + +D
Sbjct: 2382 VDMD 2385



 Score =  616 bits (1588), Expect = e-176
 Identities = 392/788 (49%), Positives = 466/788 (59%), Gaps = 86/788 (10%)

Query: 167  DEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220

Query: 226  NIKITFEEDEVNSTLVVDR---ESSHDECQD------ALNILPVPGPTSSATNVSMVVSA 276
            +   + EE  +   L VDR   +   +E QD      +  +L V  P     ++    S 
Sbjct: 1221 SAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYS- 1279

Query: 277  GPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKD 336
                      + LE  +  +P        F  L+EK     L      ++ K K    + 
Sbjct: 1280 -------TPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 1328

Query: 337  LIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNE 396
              K   R  ++ +E++     + + EL   K              E L++  D   S   
Sbjct: 1329 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRCYSTPS 1376

Query: 397  HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKS 456
                L    +P +S    L++             Q++    D D+ E  Q    E+ Q  
Sbjct: 1377 GCLELTDSCQPYRSAFYVLEQ-------------QRVGMAVDMDEIEKYQ--EVEEDQDP 1421

Query: 457  SAP---REMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIG 513
            S P   RE+   +E EV +DSL  C  T S      D  QP+     + EE       +G
Sbjct: 1422 SCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLG 1476

Query: 514  SSSHVEREDAVHIIPENESDDEEEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTPSI 570
             +  V+R        + + ++EE+E++ P  P   R L E  E EV Q+S D  YSTPS 
Sbjct: 1477 LALDVDR-------IKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 1529

Query: 571  PPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKED 611
              E   S + Y S+F++LEE  V  ++D+G                   R R  +  +ED
Sbjct: 1530 CLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 1589

Query: 612  QEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 671
            Q    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLA
Sbjct: 1590 QNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLA 1649

Query: 672  VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPY 731
            VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPY
Sbjct: 1650 VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY 1709

Query: 732  SSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 791
            SSAVYSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS
Sbjct: 1710 SSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 1769

Query: 792  TPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 851
            TPSSCLEQPDS QPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE
Sbjct: 1770 TPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1829

Query: 852  GEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQH 911
            GEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+QH
Sbjct: 1830 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQH 1889

Query: 912  ISFALYVD 919
            +  A+ +D
Sbjct: 1890 VGLAVDMD 1897



 Score =  613 bits (1582), Expect = e-175
 Identities = 394/784 (50%), Positives = 468/784 (59%), Gaps = 80/784 (10%)

Query: 167  DEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442

Query: 226  NIKITFEEDEVNSTLVVDR-ESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKA 284
            +   + EE  +   L VDR +   +E +D        GP               LS E  
Sbjct: 2443 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQ-------GPPCPR-----------LSRELL 2484

Query: 285  EMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYE----ECKDLIKF 340
            E+   E+ +    +            + C     + F A ++N   +     E +   K 
Sbjct: 2485 EVVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEENHVGFSLDVGEIEKKGKG 2543

Query: 341  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 400
              R  R+ K+E+   + K+ EE +       ++E    +  E L++  D   S       
Sbjct: 2544 KKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 2602

Query: 401  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR 460
            L    +P +S    L++Q              +    D D+ E  Q    E+ Q  S PR
Sbjct: 2603 LTDSCQPYRSAFYVLEQQ-------------HVGLAVDMDEIEKYQE--VEEDQDPSCPR 2647

Query: 461  ---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSH 517
               E+   +E EV +DSL+ C  T S      D  QP+     + EE       +G +  
Sbjct: 2648 LSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALD 2702

Query: 518  VEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEM 574
            V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E 
Sbjct: 2703 VDRI---------KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 2753

Query: 575  LASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEAT 615
              S + Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ   
Sbjct: 2754 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 2813

Query: 616  GPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675
             PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMD
Sbjct: 2814 CPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMD 2873

Query: 676  EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAV 735
            EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAV
Sbjct: 2874 EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 2933

Query: 736  YSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 795
            YSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS
Sbjct: 2934 YSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 2993

Query: 796  CLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 855
            CLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED
Sbjct: 2994 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 3053

Query: 856  QNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA 915
            QNPPCPRL+  L++ + P+VLQDSLD CYSTPS   EL DS Q YRS FY  E+Q +  A
Sbjct: 3054 QNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLA 3113

Query: 916  LYVD 919
            + +D
Sbjct: 3114 VDMD 3117



 Score =  605 bits (1560), Expect = e-173
 Identities = 324/468 (69%), Positives = 360/468 (76%), Gaps = 8/468 (1%)

Query: 460  REMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL-IGS---- 514
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L +G     
Sbjct: 2969 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 3028

Query: 515  SSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVP---QESWDEGYSTPSIP 571
                +R              E EE++ P  PR  +E  +E+ P   Q+S D  YSTPS  
Sbjct: 3029 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGC 3088

Query: 572  PEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631
             E+  S + Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLSRELLDEKGPEV
Sbjct: 3089 LELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEV 3148

Query: 632  LQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSC 691
            LQDSL RCYSTPSGCLEL DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSC
Sbjct: 3149 LQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSC 3208

Query: 692  PRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDR 751
            PRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYSLEEQYLGLALD+DR
Sbjct: 3209 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 3268

Query: 752  IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFY 811
            IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QPYGSSFY
Sbjct: 3269 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 3328

Query: 812  ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVE 871
            ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+  L++ +
Sbjct: 3329 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 3388

Query: 872  EPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
             PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+QH+  A+ +D
Sbjct: 3389 GPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMD 3436



 Score =  601 bits (1550), Expect = e-172
 Identities = 330/505 (65%), Positives = 367/505 (72%), Gaps = 39/505 (7%)

Query: 440  DDNEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHR 496
            D +E  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976

Query: 497  KTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 553
                + EE       +G +  V+R          + D EEEE++GP  PR    L E  E
Sbjct: 977  SAVYSLEEQ-----YLGLALDVDRI---------KKDQEEEEDQGPPCPRLSRELLEVVE 1022

Query: 554  EEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 600
             EV Q+S D  YSTPS   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082

Query: 601  ------RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQ 654
                  R R  +  +EDQ    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQ
Sbjct: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142

Query: 655  PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRW 714
            PYRSAFYVLEQQRVG AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R 
Sbjct: 1143 PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202

Query: 715  YSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELL 774
            YSTPSGY ELPDLGQPYSSAVYSLEEQYLGLALD+DRIKKD+EEEEDQ PPCPRLSRELL
Sbjct: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELL 1262

Query: 775  EVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 834
            EVV PEVLQDSLDRCYSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1263 EVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322

Query: 835  KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELP 894
            KRRGRRSKKERRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL 
Sbjct: 1323 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1382

Query: 895  DSFQHYRSVFYSFEEQHISFALYVD 919
            DS Q YRS FY  E+Q +  A+ +D
Sbjct: 1383 DSCQPYRSAFYVLEQQRVGMAVDMD 1407



 Score =  570 bits (1470), Expect = e-162
 Identities = 318/528 (60%), Positives = 369/528 (69%), Gaps = 39/528 (7%)

Query: 440  DDNEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHR 496
            D +E  + +  E+ Q  S PR   E+   +  EV +DSL+ C  T S      DS QP+R
Sbjct: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174

Query: 497  KTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 553
                  E+ +V   +               + E E   E EE++ P  PR    L + +E
Sbjct: 3175 SAFYILEQQRVGLAVD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKE 3220

Query: 554  EEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQE 613
             EV Q+S D  YSTPS   E+    + YSS  +SLEEQ + +A+D+ R + DQ ++EDQ 
Sbjct: 3221 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG 3280

Query: 614  ATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 673
               PRLSRELL+   PEVLQDSL RCYSTPS CLE  DSCQPY S+FY LE++ VG ++D
Sbjct: 3281 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 3340

Query: 674  MDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRW 714
            + EIEK                    +E EEDQ+P CPRLSRELLDEK PEVLQDSL R 
Sbjct: 3341 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRC 3400

Query: 715  YSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELL 774
            YSTPSG  EL D  QPY SA Y LE+Q++GLA+D+D I+K QE EEDQ P CPRLSRELL
Sbjct: 3401 YSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 3460

Query: 775  EVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 834
            +  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV +IEKKGKGK
Sbjct: 3461 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGK 3520

Query: 835  KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELP 894
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEE EVLQDSLD CYSTPSMYFELP
Sbjct: 3521 KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELP 3580

Query: 895  DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ 942
            DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQM VIFPQ
Sbjct: 3581 DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 3628



 Score =  424 bits (1089), Expect = e-118
 Identities = 325/880 (36%), Positives = 441/880 (50%), Gaps = 120/880 (13%)

Query: 90   EELRQYKVLVHSQE-------RELTQLKEK--LREGRDASRSLNEHLQALLTPDEPDKSQ 140
            +E+ +Y+ +   Q+       REL   KE   L++  D   S       L    +P  S 
Sbjct: 1163 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1222

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPR---EVQKAEES 197
               L+EQ   G  L    V ++  + +E+ED+D            P PR   E+ +    
Sbjct: 1223 VYSLEEQYL-GLALD---VDRIKKDEEEEEDQD-----------PPCPRLSRELLEVVAP 1267

Query: 198  KVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNI 257
            +V +DSL+ C  T S+     DS QP+ +     EE  V  +L V       +       
Sbjct: 1268 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK------- 1320

Query: 258  LPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKK--QQFRNLKEKCFL 315
                G              G    E+ +        +L  +L ++K  +  ++  ++C+ 
Sbjct: 1321 ----GKKRRGRRSKKERRRGRKEGEEDQNPPC---PRLSRELLDEKGPEVLQDSLDRCYS 1373

Query: 316  TQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQER 375
            T  +G L    +   Y           R+     E++        +E+ +Y+ +   Q+ 
Sbjct: 1374 TP-SGCLELTDSCQPY-----------RSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDP 1421

Query: 376  ELTQLREKL---REGRDASRSLNEHLQA----LLTPD--EPDKSQGQDLQEQLAEGCRLA 426
               +L  +L   +E      SLN         L  PD  +P  S    L+EQ   G  L 
Sbjct: 1422 SCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL-GLALD 1480

Query: 427  QHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSH 486
               ++K   E +++D +     ++         RE+ +  E EV +DSL+ C  T S+  
Sbjct: 1481 VDRIKKDQEEEEDEDQDPPCPRLS---------RELLEVVEPEVLQDSLDRCYSTPSSCL 1531

Query: 487  GPYDSNQPHRKTKITFEEDKVDSTL-IG----SSSHVEREDAVHIIPENESDDEEEEEKG 541
               DS QP+  +    EE+ V  +L +G         +R              E EE++ 
Sbjct: 1532 EQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 1591

Query: 542  PVSPRNLQESEEE---EVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVD 598
            P  PR  +E  +E   EV Q+S D  YSTPS   E+  S + Y S F+ LE+Q V +AVD
Sbjct: 1592 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVD 1651

Query: 599  IGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRS 658
            +      Q  +EDQ+ + PRLSRELLDEK PEVLQDSL RCYSTPSG LEL D  QPY S
Sbjct: 1652 MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS 1711

Query: 659  AFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTP 718
            A Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSL R YSTP
Sbjct: 1712 AVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 1771

Query: 719  SGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKD-------------------QEEE 759
            S   E PD  QPY S+ Y+LEE ++G +LD+  I+K                    +E E
Sbjct: 1772 SSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 1831

Query: 760  EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVG 819
            EDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DS QPY S+FY LE++HVG
Sbjct: 1832 EDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVG 1891

Query: 820  FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDS 879
             ++D+ EIEK                    +E EEDQ+P CPRL+  L++ +EPEVLQDS
Sbjct: 1892 LAVDMDEIEK-------------------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1932

Query: 880  LDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
            LD CYSTPS Y ELPD  Q Y S  YS EEQ++  AL VD
Sbjct: 1933 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 1972



 Score =  424 bits (1089), Expect = e-118
 Identities = 329/883 (37%), Positives = 443/883 (50%), Gaps = 126/883 (14%)

Query: 90   EELRQYKVLVHSQERELTQLKEKLREGRDAS---RSLNEHLQA----LLTPD--EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++      SLN         L  PD  +P  S 
Sbjct: 1407 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSA 1466

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPR---EVQKAEES 197
               L+EQ   G  L    ++K   E +EDED+D            P PR   E+ +  E 
Sbjct: 1467 VYSLEEQYL-GLALDVDRIKK-DQEEEEDEDQD-----------PPCPRLSRELLEVVEP 1513

Query: 198  KVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNI 257
            +V +DSL+ C  T S+     DS QP+ +     EE+ V  +L V       +       
Sbjct: 1514 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGK------- 1566

Query: 258  LPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKK--QQFRNLKEKCFL 315
                G              G    E+ +        +L  +L ++K  +  ++  ++C+ 
Sbjct: 1567 ----GKKRRGRRSKKERRRGRKEGEEDQNPPC---PRLSRELLDEKGPEVLQDSLDRCYS 1619

Query: 316  TQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQE- 374
            T  +G L    +   Y           R+     E++        +E+ +Y+ +   Q+ 
Sbjct: 1620 TP-SGCLELTDSCQPY-----------RSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDP 1667

Query: 375  ------RELTQLREK--LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLA 426
                  REL   +E   L++  D   S       L    +P  S    L+EQ   G  L 
Sbjct: 1668 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL-GLALD 1726

Query: 427  QHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYS 483
               ++K     D ++ ED         Q    PR   E+ +  E EV +DSL+ C  T S
Sbjct: 1727 VDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 1772

Query: 484  NSHGPYDSNQPHRKTKITFEEDKVDSTL-IG----SSSHVEREDAVHIIPENESDDEEEE 538
            +     DS QP+  +    EE+ V  +L +G         +R              E EE
Sbjct: 1773 SCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 1832

Query: 539  EKGPVSPRNLQESEEE---EVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCM 595
            ++ P  PR  +E  +E   EV Q+S D  YSTPS   E+  S + Y S F+ LE+Q V +
Sbjct: 1833 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGL 1892

Query: 596  AVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQP 655
            AVD+      Q  +EDQ+ + PRLSRELLDEK PEVLQDSL RCYSTPSG LEL D  QP
Sbjct: 1893 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 1952

Query: 656  YRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWY 715
            Y SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSL R Y
Sbjct: 1953 YSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 2012

Query: 716  STPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKD-------------------Q 756
            STPS   E PD  QPY S+ Y+LEE ++G +LD+  I+K                    +
Sbjct: 2013 STPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 2072

Query: 757  EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEK 816
            E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DS QPY S+FY LE++
Sbjct: 2073 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ 2132

Query: 817  HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVL 876
            HVG ++D+ EIEK                    +E EEDQ+P CPRL+  L++ +EPEVL
Sbjct: 2133 HVGLAVDMDEIEK-------------------YQEVEEDQDPSCPRLSRELLDEKEPEVL 2173

Query: 877  QDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
            QDSLD CYSTPS Y ELPD  Q Y S  YS EEQ++  AL VD
Sbjct: 2174 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2216



 Score =  419 bits (1078), Expect = e-117
 Identities = 327/883 (37%), Positives = 441/883 (49%), Gaps = 128/883 (14%)

Query: 90   EELRQYKVLVHSQE-------RELTQLKEK--LREGRDASRSLNEHLQALLTPDEPDKSQ 140
            +E+ +Y+ +   Q+       REL   KE   L++  D   S       L    +P  S 
Sbjct: 2141 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2200

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPR---EVQKAEES 197
               L+EQ   G  L    V ++  + +E+ED+             P PR   E+ +  E 
Sbjct: 2201 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQG-----------PPCPRLSRELLEVVEP 2245

Query: 198  KVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNI 257
            +V +DSL+ C  T S+     DS QP+ +     EE+ V  +L V       +       
Sbjct: 2246 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGK------- 2298

Query: 258  LPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKK--QQFRNLKEKCFL 315
                G              G    E+ +        +L  +L ++K  +  ++  ++C+ 
Sbjct: 2299 ----GKKRRGRRSKKERRRGRKEGEEDQNPPC---PRLSRELLDEKGPEVLQDSLDRCYS 2351

Query: 316  TQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQE- 374
            T  +G L    +   Y           R+     E++        +E+ +Y+ +   Q+ 
Sbjct: 2352 TP-SGCLELTDSCQPY-----------RSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDP 2399

Query: 375  ------RELTQLREK--LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLA 426
                  REL   +E   L++  D   S       L    +P  S    L+EQ   G  L 
Sbjct: 2400 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL-GLALD 2458

Query: 427  QHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYS 483
               ++K     D ++ ED         Q    PR   E+ +  E EV +DSL+ C  T S
Sbjct: 2459 VDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2504

Query: 484  NSHGPYDSNQPHRKTKITFEEDKVDSTL-IG----SSSHVEREDAVHIIPENESDDEEEE 538
            +     DS QP+  +    EE+ V  +L +G         +R              E EE
Sbjct: 2505 SCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 2564

Query: 539  EKGPVSPRNLQESEEE---EVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCM 595
            ++ P  PR  +E  +E   EV Q+S D  YSTPS   E+  S + Y S F+ LE+Q V +
Sbjct: 2565 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGL 2624

Query: 596  AVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQP 655
            AVD+      Q  +EDQ+ + PRLSRELLDEK PEVLQDSL RCYSTPSG LEL D  QP
Sbjct: 2625 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 2684

Query: 656  YRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWY 715
            Y SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSL R Y
Sbjct: 2685 YSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 2744

Query: 716  STPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKD-------------------Q 756
            STPS   E PD  QPY S+ Y+LEE+++G +LD+  I+K                    +
Sbjct: 2745 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 2804

Query: 757  EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEK 816
            E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DS QPY S+FY LE++
Sbjct: 2805 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ 2864

Query: 817  HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVL 876
            HVG ++D+ EIEK                    +E EEDQ+P CPRL+  L++ +EPEVL
Sbjct: 2865 HVGLAVDMDEIEK-------------------YQEVEEDQDPSCPRLSRELLDEKEPEVL 2905

Query: 877  QDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
            QDSLD CYSTPS Y ELPD  Q Y S  YS EEQ++  AL VD
Sbjct: 2906 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2948



 Score =  399 bits (1026), Expect = e-111
 Identities = 308/810 (38%), Positives = 400/810 (49%), Gaps = 153/810 (18%)

Query: 90   EELRQYKVLVHSQE-------RELTQLKEK--LREGRDASRSLNEHLQALLTPDEPDKSQ 140
            +E+ +Y+ +   Q+       REL   KE   L++  D   S       L    +P  S 
Sbjct: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPR---EVQKAEES 197
               L+EQ   G  L    V ++  + +E+ED+             P PR   E+ +  E 
Sbjct: 2933 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQG-----------PPCPRLSRELLEVVEP 2977

Query: 198  KVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVV-------------DR 244
            +V +DSL+ C  T S+     DS QP+ +     EE  V  +L V              R
Sbjct: 2978 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3037

Query: 245  ESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSE-------KAEMNILEINEKLRP 297
             S  +  +          P     +  ++   GP   +             LE+ +  +P
Sbjct: 3038 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQP 3097

Query: 298  QLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEEC-KDLIKFMLRNERQFKEEKLAEQ 356
                 +  F  L++     Q  G   +     KY+E  +D      R  R+  +EK  E 
Sbjct: 3098 Y----RSAFYVLEQ-----QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEV 3148

Query: 357  LKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQ 416
            L+ + +        ++      +L +  +  R A   L E  +  L  D  +  + Q+++
Sbjct: 3149 LQDSLD------RCYSTPSGCLELCDSCQPYRSAFYIL-EQQRVGLAVDMDEIEKYQEVE 3201

Query: 417  EQLAEGC-RLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSL 475
            E     C RL++ L+ +  PE                                 V +DSL
Sbjct: 3202 EDQDPSCPRLSRELLDEKEPE---------------------------------VLQDSL 3228

Query: 476  EECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDE 535
            + C  T S      D  QP+     + EE       +G +  V+R          + D E
Sbjct: 3229 DRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALDVDR---------IKKDQE 3274

Query: 536  EEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQ 592
            EEE++GP  P   R L E  E EV Q+S D  YSTPS   E   S + Y S+F++LEE+ 
Sbjct: 3275 EEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKH 3334

Query: 593  VCMAVDIG-------------------RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQ 633
            V  ++D+G                   R R  +  +EDQ    PRLSRELLDEKGPEVLQ
Sbjct: 3335 VGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQ 3394

Query: 634  DSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPR 693
            DSL RCYSTPSGCLEL DSCQPYRSAFYVLEQQ VGLAVDMDEIEKYQEVEEDQDPSCPR
Sbjct: 3395 DSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPR 3454

Query: 694  LSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIK 753
            LSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYSLEEQYLGLALD+D+I+
Sbjct: 3455 LSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIE 3514

Query: 754  KD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 794
            K                    +E EEDQ PPCPRL+  L+EV E EVLQDSLDRCYSTPS
Sbjct: 3515 KKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPS 3574

Query: 795  SCLEQPDSWQPYGSSFYALEEKHVGFSLDV 824
               E PDS+Q Y S FY+ EE+H+ F+L V
Sbjct: 3575 MYFELPDSFQHYRSVFYSFEEQHISFALYV 3604



 Score =  230 bits (586), Expect = 5e-60
 Identities = 200/608 (32%), Positives = 281/608 (46%), Gaps = 84/608 (13%)

Query: 177  EEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEE 233
            +E E+    P PR   E+   +  KV +DSL+ C  T S     CDS QP+++     E+
Sbjct: 3048 KEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3107

Query: 234  DEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINE 293
              V   + +D    + E ++  +      P+    +  ++   GP           E+ +
Sbjct: 3108 QRVGLAVDMDEIEKYQEVEEDQD------PSCPRLSRELLDEKGP-----------EVLQ 3150

Query: 294  KLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKE-EK 352
                +          L + C   + A ++  QQ      +  ++ K+    E Q     +
Sbjct: 3151 DSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPR 3210

Query: 353  LAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQG 412
            L+ +L   +E                   E L++  D   S       L    +P  S  
Sbjct: 3211 LSRELLDEKE------------------PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 3252

Query: 413  QDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAP---REMQKAEEKE 469
              L+EQ   G  L    ++K     D ++ ED         Q    P   RE+ +  E E
Sbjct: 3253 YSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPE 3297

Query: 470  VPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL-IG----SSSHVEREDAV 524
            V +DSL+ C  T S+     DS QP+  +    EE  V  +L +G         +R    
Sbjct: 3298 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 3357

Query: 525  HIIPENESDDEEEEEKGPVSPRNLQESEEE---EVPQESWDEGYSTPSIPPEMLASYKSY 581
                      E EE++ P  PR  +E  +E   EV Q+S D  YSTPS   E+  S + Y
Sbjct: 3358 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPY 3417

Query: 582  SSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYS 641
             S F+ LE+Q V +AVD+      Q  +EDQ+ + PRLSRELLDEK PEVLQDSL RCYS
Sbjct: 3418 RSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS 3477

Query: 642  TPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQE 682
            TPSG LEL D  QPY SA Y LE+Q +GLA+D+D+IEK                    +E
Sbjct: 3478 TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKE 3537

Query: 683  VEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQY 742
             EEDQ+P CPRL+  L++ +E EVLQDSL R YSTPS Y ELPD  Q Y S  YS EEQ+
Sbjct: 3538 GEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQH 3597

Query: 743  LGLALDLD 750
            +  AL +D
Sbjct: 3598 ISFALYVD 3605



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 177  EEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEE 233
            +E E+    P PR   E+   +  +V +DSL+ C  T S      DS QP+++     E+
Sbjct: 1094 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 1153

Query: 234  DEVNSTLVVDRESSHDECQD 253
              V   + +D    + E ++
Sbjct: 1154 QRVGFAVDMDEIEKYQEVEE 1173


>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
           sapiens]
          Length = 4621

 Score = 1713 bits (4437), Expect = 0.0
 Identities = 862/919 (93%), Positives = 881/919 (95%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCF+TQLAGFLAN+QKKY Y
Sbjct: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFVTQLAGFLANQQKKYNY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
           RSLNEHLQALLT DEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEE E
Sbjct: 121 RSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +S APREVQK EESKV EDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL
Sbjct: 181 KVQKSSAPREVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKL PQLA
Sbjct: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLA 300

Query: 301 EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
           EKKQQFRNLKE+CF+TQLAGFLANQQ KYKYEECKDLIK MLRNERQFKEEKLAEQLKQA
Sbjct: 301 EKKQQFRNLKERCFVTQLAGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQA 360

Query: 361 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 420
           EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 361 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 420

Query: 421 EGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
           EGCRLAQHLVQKLSPENDNDD+EDVQVE+AEKVQKSSAPREMQKAEEKEVPEDS EECAI
Sbjct: 421 EGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAI 480

Query: 481 TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEK 540
           TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE EDAVHIIPENESDDEEEEEK
Sbjct: 481 TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 540

Query: 541 GPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG 600
           GPVSPRNLQESEEEEVPQESWDEGYST SIPPEMLASY+SYSSTFHSLEEQQVCMAVDIG
Sbjct: 541 GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG 600

Query: 601 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAF 660
           RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAF
Sbjct: 601 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF 660

Query: 661 YVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSG 720
           YVLEQQR+GLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSG
Sbjct: 661 YVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 720

Query: 721 YPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780
           Y ELPDLGQPYSSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPE
Sbjct: 721 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPE 780

Query: 781 VLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840
           VLQDSLDRCYSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
Sbjct: 781 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840

Query: 841 SKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHY 900
           SKKERRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSLD  YSTPS   EL DS Q Y
Sbjct: 841 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPY 900

Query: 901 RSVFYSFEEQHISFALYVD 919
           RS FY  E+Q +  A+ +D
Sbjct: 901 RSAFYVLEQQRVGLAVDMD 919



 Score = 1008 bits (2607), Expect = 0.0
 Identities = 581/954 (60%), Positives = 656/954 (68%), Gaps = 97/954 (10%)

Query: 1    MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
            MVVSAGP SSEKAEMNILEINEKL PQLAE KQQF NLKERCF+TQLAGFLAN+QKKYKY
Sbjct: 272  MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFLANQQKKYKY 331

Query: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
            EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRDAS
Sbjct: 332  EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 391

Query: 121  RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
            RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE  E
Sbjct: 392  RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAE 451

Query: 181  KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
            KV +S APRE+QKAEE +V EDS EECAIT SNSHGP DSNQPH+  KITFEED+V+STL
Sbjct: 452  KVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511

Query: 241  VVDRESSHDECQDALNILPV----------PGPTSSATNVSMVVSAGPLSSEKAEMNILE 290
            +    SSH E +DA++I+P            GP S            P  S     + L 
Sbjct: 512  I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 569

Query: 291  INEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKE 350
            I  ++          F +L+E+         +A    ++++++ K             KE
Sbjct: 570  IPPEMLASYQSYSSTFHSLEEQQVC------MAVDIGRHRWDQVK-------------KE 610

Query: 351  EKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKS 410
            ++ A   + + EL   K              E L++  D   S       L    +P +S
Sbjct: 611  DQEATGPRLSRELLDEKG------------PEVLQDSLDRCYSTPSGCLELTDSCQPYRS 658

Query: 411  QGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEE 467
                L++Q             ++    D D+ E  Q    E+ Q  S PR   E+   +E
Sbjct: 659  AFYVLEQQ-------------RIGLAVDMDEIEKYQE--VEEDQDPSCPRLSRELLDEKE 703

Query: 468  KEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHII 527
             EV +DSL+ C  T S      D  QP+     + EE       +G +  V+R       
Sbjct: 704  PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALDVDR------- 751

Query: 528  PENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSST 584
               + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E   S + Y S+
Sbjct: 752  --TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 809

Query: 585  FHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGPRLSRELLD 625
            F++LEE+ V  ++D+G                   R R  +  +EDQ    PRLSRELLD
Sbjct: 810  FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLD 869

Query: 626  EKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEE 685
            EKGPEVLQDSL R YSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEE
Sbjct: 870  EKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEE 929

Query: 686  DQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGL 745
            DQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYSLEEQYLGL
Sbjct: 930  DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 989

Query: 746  ALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQP 805
            ALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QP
Sbjct: 990  ALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 1049

Query: 806  YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNG 865
            YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+ 
Sbjct: 1050 YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 1109

Query: 866  VLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
             L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+Q +  A+ +D
Sbjct: 1110 ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 1163



 Score =  719 bits (1855), Expect = 0.0
 Identities = 442/813 (54%), Positives = 507/813 (62%), Gaps = 78/813 (9%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 3857 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 3916

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGP 278
            D  QP+ +   + EE  +   L VDR     E ++       P P  S   + +V     
Sbjct: 3917 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQG---PPCPRLSRELLEVVEPEVL 3973

Query: 279  LSS----EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEEC 334
              S         + LE  +  +P        F  L+EK     L      ++ K K    
Sbjct: 3974 QDSLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 4029

Query: 335  KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSL 394
            +   K   R  ++ +E++     + + EL   K              E L++  D   S 
Sbjct: 4030 RRSKKERRRGRKEGEEDQTPPCPRLSRELLDEKG------------PEVLQDSLDRCYST 4077

Query: 395  NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQ 454
                  L    +P +S    L++Q             ++    D D+ E  Q    E+ Q
Sbjct: 4078 PSGCLELTDSCQPYRSAFYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQ 4122

Query: 455  KSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
              S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE       
Sbjct: 4123 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----Y 4177

Query: 512  IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTP 568
            +G +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTP
Sbjct: 4178 LGLALDVDR---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 4228

Query: 569  SIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKK 609
            S   E   S + Y S+F++LEE+ V  ++D+G                   R R  +  +
Sbjct: 4229 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 4288

Query: 610  EDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 669
            EDQ    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG
Sbjct: 4289 EDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 4348

Query: 670  LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQ 729
            LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQ
Sbjct: 4349 LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 4408

Query: 730  PYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 789
            PYSSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC
Sbjct: 4409 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 4468

Query: 790  YSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 849
            YSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGR
Sbjct: 4469 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGR 4528

Query: 850  KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909
            KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE
Sbjct: 4529 KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 4588

Query: 910  QHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ 942
            QHISFALYVDNRFFTLTVTSLHLVFQM VIFPQ
Sbjct: 4589 QHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 4621



 Score =  624 bits (1609), Expect = e-178
 Identities = 399/790 (50%), Positives = 469/790 (59%), Gaps = 78/790 (9%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 2130 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 2189

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGP 278
            D  QP+ +   + EE  +   L VDR     E ++       P P  S   + +V     
Sbjct: 2190 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQG---PPCPRLSRELLEVVEPEVL 2246

Query: 279  LSS----EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEEC 334
              S         + LE  +  +P        F  L+EK     L      ++ K K    
Sbjct: 2247 QDSLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2302

Query: 335  KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSL 394
            +   K   R  ++ +E++     + + EL   K              E L++  D S S 
Sbjct: 2303 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRSYST 2350

Query: 395  NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQ 454
                  L    +P +S    L++Q             ++    D D+ E  Q    E+ Q
Sbjct: 2351 PSGCLELTDSCQPYRSAFYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQ 2395

Query: 455  KSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
              S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE       
Sbjct: 2396 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----Y 2450

Query: 512  IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTP 568
            +G +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTP
Sbjct: 2451 LGLALDVDR---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 2501

Query: 569  SIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKK 609
            S   E   S + Y S+F++LEE+ V  ++D+G                   R R  +  +
Sbjct: 2502 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 2561

Query: 610  EDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 669
            EDQ    PRLSRELLDEKGPEVLQDSL R YSTPSGCLELTDSCQPYRSAFYVLEQQRVG
Sbjct: 2562 EDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 2621

Query: 670  LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQ 729
            LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQ
Sbjct: 2622 LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 2681

Query: 730  PYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 789
            PYSSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC
Sbjct: 2682 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 2741

Query: 790  YSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 849
            YSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR
Sbjct: 2742 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 2801

Query: 850  KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909
            KEGEEDQNPPCPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE
Sbjct: 2802 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 2861

Query: 910  QHISFALYVD 919
            Q++  AL VD
Sbjct: 2862 QYLGLALDVD 2871



 Score =  617 bits (1590), Expect = e-176
 Identities = 395/790 (50%), Positives = 467/790 (59%), Gaps = 78/790 (9%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 666  QRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 725

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGP 278
            D  QP+ +   + EE  +   L VDR     E ++       P P  S   + +V     
Sbjct: 726  DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQG---PPCPRLSRELLEVVEPEVL 782

Query: 279  LSS----EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEEC 334
              S         + LE  +  +P        F  L+EK     L      ++ K K    
Sbjct: 783  QDSLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838

Query: 335  KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSL 394
            +   K   R  ++ +E++     + + EL   K              E L++  D S S 
Sbjct: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRSYST 886

Query: 395  NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQ 454
                  L    +P +S    L++Q             ++    D D+ E  Q    E+ Q
Sbjct: 887  PSGCLELTDSCQPYRSAFYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQ 931

Query: 455  KSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
              S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE       
Sbjct: 932  DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----Y 986

Query: 512  IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTP 568
            +G +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTP
Sbjct: 987  LGLALDVDR---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 1037

Query: 569  SIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKK 609
            S   E   S + Y S+F++LEE+ V  ++D+G                   R R  +  +
Sbjct: 1038 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 1097

Query: 610  EDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 669
            EDQ    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG
Sbjct: 1098 EDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 1157

Query: 670  LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQ 729
            LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQ
Sbjct: 1158 LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 1217

Query: 730  PYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 789
            PYSSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC
Sbjct: 1218 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 1277

Query: 790  YSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 849
            YSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR
Sbjct: 1278 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 1337

Query: 850  KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909
            KEGEEDQNPPCPRL+  L++ + PEVLQDSLD  YSTPS   EL DS Q YRS FY  E+
Sbjct: 1338 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQ 1397

Query: 910  QHISFALYVD 919
            Q +  A+ +D
Sbjct: 1398 QRVGLAVDMD 1407



 Score =  616 bits (1589), Expect = e-176
 Identities = 395/790 (50%), Positives = 467/790 (59%), Gaps = 78/790 (9%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 1154 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1213

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGP 278
            D  QP+ +   + EE  +   L VDR     E ++       P P  S   + +V     
Sbjct: 1214 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQG---PPCPRLSRELLEVVEPEVL 1270

Query: 279  LSS----EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEEC 334
              S         + LE  +  +P        F  L+EK     L      ++ K K    
Sbjct: 1271 QDSLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326

Query: 335  KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSL 394
            +   K   R  ++ +E++     + + EL   K              E L++  D S S 
Sbjct: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRSYST 1374

Query: 395  NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQ 454
                  L    +P +S    L++Q             ++    D D+ E  Q    E+ Q
Sbjct: 1375 PSGCLELTDSCQPYRSAFYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQ 1419

Query: 455  KSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
              S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE       
Sbjct: 1420 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----Y 1474

Query: 512  IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTP 568
            +G +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTP
Sbjct: 1475 LGLALDVDR---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 1525

Query: 569  SIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKK 609
            S   E   S + Y S+F++LEE+ V  ++D+G                   R R  +  +
Sbjct: 1526 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 1585

Query: 610  EDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 669
            EDQ    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG
Sbjct: 1586 EDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 1645

Query: 670  LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQ 729
            LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQ
Sbjct: 1646 LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 1705

Query: 730  PYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 789
            PYSSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC
Sbjct: 1706 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 1765

Query: 790  YSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 849
            YSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR
Sbjct: 1766 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 1825

Query: 850  KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909
            KEGEEDQNPPCPRL+  L++ + PEVLQDSLD  YSTPS   EL DS Q YRS FY  E+
Sbjct: 1826 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQ 1885

Query: 910  QHISFALYVD 919
            Q +  A+ +D
Sbjct: 1886 QRVGLAVDMD 1895



 Score =  615 bits (1587), Expect = e-176
 Identities = 393/788 (49%), Positives = 467/788 (59%), Gaps = 74/788 (9%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 3369 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 3428

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNV--SMVVSA 276
            D  QP+ +   + EE  +   L VDR +  D+ ++     P P  +     V    V+  
Sbjct: 3429 DLGQPYSSAVYSLEEQYLGLALDVDR-TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 3487

Query: 277  GPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKD 336
                      + LE  +  +P        F  L+EK     L      ++ K K    + 
Sbjct: 3488 SLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 3543

Query: 337  LIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNE 396
              K   R  ++ +E++     + + EL   K              E L++  D   S   
Sbjct: 3544 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRCYSTPS 3591

Query: 397  HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKS 456
                L    +P +S    L++Q             ++    D D+ E  Q    E+ Q  
Sbjct: 3592 GCLELTDSCQPYRSAFYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQDP 3636

Query: 457  SAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIG 513
            S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE       +G
Sbjct: 3637 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLG 3691

Query: 514  SSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSI 570
             +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS 
Sbjct: 3692 LALDVDR---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 3742

Query: 571  PPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKED 611
              E   S + Y S+F++LEE+ V  ++D+G                   R R  +  +ED
Sbjct: 3743 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 3802

Query: 612  QEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 671
            Q    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA
Sbjct: 3803 QNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 3862

Query: 672  VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPY 731
            VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPY
Sbjct: 3863 VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY 3922

Query: 732  SSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 791
            SSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS
Sbjct: 3923 SSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 3982

Query: 792  TPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 851
            TPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE
Sbjct: 3983 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 4042

Query: 852  GEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQH 911
            GEEDQ PPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+Q 
Sbjct: 4043 GEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 4102

Query: 912  ISFALYVD 919
            +  A+ +D
Sbjct: 4103 VGLAVDMD 4110



 Score =  614 bits (1583), Expect = e-175
 Identities = 393/788 (49%), Positives = 467/788 (59%), Gaps = 74/788 (9%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 910  QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 969

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNV--SMVVSA 276
            D  QP+ +   + EE  +   L VDR +  D+ ++     P P  +     V    V+  
Sbjct: 970  DLGQPYSSAVYSLEEQYLGLALDVDR-TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 1028

Query: 277  GPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKD 336
                      + LE  +  +P        F  L+EK     L      ++ K K    + 
Sbjct: 1029 SLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 1084

Query: 337  LIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNE 396
              K   R  ++ +E++     + + EL   K              E L++  D   S   
Sbjct: 1085 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRCYSTPS 1132

Query: 397  HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKS 456
                L    +P +S    L++Q             ++    D D+ E  Q    E+ Q  
Sbjct: 1133 GCLELTDSCQPYRSAFYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQDP 1177

Query: 457  SAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIG 513
            S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE       +G
Sbjct: 1178 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLG 1232

Query: 514  SSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSI 570
             +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS 
Sbjct: 1233 LALDVDR---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 1283

Query: 571  PPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKED 611
              E   S + Y S+F++LEE+ V  ++D+G                   R R  +  +ED
Sbjct: 1284 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 1343

Query: 612  QEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 671
            Q    PRLSRELLDEKGPEVLQDSL R YSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA
Sbjct: 1344 QNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 1403

Query: 672  VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPY 731
            VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPY
Sbjct: 1404 VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY 1463

Query: 732  SSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 791
            SSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS
Sbjct: 1464 SSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 1523

Query: 792  TPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 851
            TPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE
Sbjct: 1524 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1583

Query: 852  GEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQH 911
            GEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+Q 
Sbjct: 1584 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 1643

Query: 912  ISFALYVD 919
            +  A+ +D
Sbjct: 1644 VGLAVDMD 1651



 Score =  613 bits (1581), Expect = e-175
 Identities = 388/773 (50%), Positives = 461/773 (59%), Gaps = 76/773 (9%)

Query: 177  EEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEE 233
            +E E+    P PR   E+   +E +V +DSL+ C  T S      D  QP+ +   + EE
Sbjct: 3140 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3199

Query: 234  DEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNV--SMVVSAGPLSSEKAEMNILEI 291
              +   L VDR +  D+ ++     P P  +     V    V+            + LE 
Sbjct: 3200 QYLGLALDVDR-TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 3258

Query: 292  NEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEE 351
             +  +P        F  L+EK     L      ++ K K    +   K   R  ++ +E+
Sbjct: 3259 PDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 3314

Query: 352  KLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQ 411
            +     + + EL   K              E L++  D   S       L    +P +S 
Sbjct: 3315 QNPPCPRLSRELLDEKG------------PEVLQDSLDRCYSTPSGCLELTDSCQPYRSA 3362

Query: 412  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEEK 468
               L++Q             ++    D D+ E  Q    E+ Q  S PR   E+   +E 
Sbjct: 3363 FYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQDPSCPRLSRELLDEKEP 3407

Query: 469  EVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIP 528
            EV +DSL+ C  T S      D  QP+     + EE       +G +  V+R        
Sbjct: 3408 EVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALDVDR-------- 3454

Query: 529  ENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTF 585
              + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E   S + Y S+F
Sbjct: 3455 -TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 3513

Query: 586  HSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGPRLSRELLDE 626
            ++LEE+ V  ++D+G                   R R  +  +EDQ    PRLSRELLDE
Sbjct: 3514 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 3573

Query: 627  KGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED 686
            KGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED
Sbjct: 3574 KGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED 3633

Query: 687  QDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLA 746
            QDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYSLEEQYLGLA
Sbjct: 3634 QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 3693

Query: 747  LDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPY 806
            LD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QPY
Sbjct: 3694 LDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3753

Query: 807  GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGV 866
            GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+  
Sbjct: 3754 GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE 3813

Query: 867  LMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
            L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+Q +  A+ +D
Sbjct: 3814 LLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 3866



 Score =  612 bits (1579), Expect = e-175
 Identities = 394/790 (49%), Positives = 466/790 (58%), Gaps = 78/790 (9%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 1642 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1701

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGP 278
            D  QP+ +   + EE  +   L VDR     E ++       P P  S   + +V     
Sbjct: 1702 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQG---PPCPRLSRELLEVVEPEVL 1758

Query: 279  LSS----EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEEC 334
              S         + LE  +  +P        F  L+EK     L      ++ K K    
Sbjct: 1759 QDSLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1814

Query: 335  KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSL 394
            +   K   R  ++ +E++     + + EL   K              E L++  D S S 
Sbjct: 1815 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRSYST 1862

Query: 395  NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQ 454
                  L    +P +S    L++Q             ++    D D+ E  Q    E+ Q
Sbjct: 1863 PSGCLELTDSCQPYRSAFYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQ 1907

Query: 455  KSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
              S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE       
Sbjct: 1908 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----Y 1962

Query: 512  IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTP 568
            +G +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTP
Sbjct: 1963 LGLALDVDR---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 2013

Query: 569  SIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKK 609
            S   E   S + Y S+F++LEE+ V  ++D+G                   R R  +  +
Sbjct: 2014 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 2073

Query: 610  EDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 669
            EDQ    PRLSRELLDEKGPEVLQDSL R YSTPSGCLELTDSCQPYRSAFYVLEQQRVG
Sbjct: 2074 EDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 2133

Query: 670  LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQ 729
            LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQ
Sbjct: 2134 LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 2193

Query: 730  PYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 789
            PYSSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC
Sbjct: 2194 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 2253

Query: 790  YSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 849
            YSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR
Sbjct: 2254 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 2313

Query: 850  KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909
            KEGEEDQNPPCPRL+  L++ + PEVLQDSLD  YSTPS   EL DS Q YRS FY  E+
Sbjct: 2314 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQ 2373

Query: 910  QHISFALYVD 919
            Q +  A+ +D
Sbjct: 2374 QRVGLAVDMD 2383



 Score =  610 bits (1573), Expect = e-174
 Identities = 392/788 (49%), Positives = 466/788 (59%), Gaps = 74/788 (9%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 1398 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1457

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNV--SMVVSA 276
            D  QP+ +   + EE  +   L VDR +  D+ ++     P P  +     V    V+  
Sbjct: 1458 DLGQPYSSAVYSLEEQYLGLALDVDR-TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 1516

Query: 277  GPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKD 336
                      + LE  +  +P        F  L+EK     L      ++ K K    + 
Sbjct: 1517 SLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 1572

Query: 337  LIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNE 396
              K   R  ++ +E++     + + EL   K              E L++  D   S   
Sbjct: 1573 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRCYSTPS 1620

Query: 397  HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKS 456
                L    +P +S    L++Q             ++    D D+ E  Q    E+ Q  
Sbjct: 1621 GCLELTDSCQPYRSAFYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQDP 1665

Query: 457  SAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIG 513
            S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE       +G
Sbjct: 1666 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLG 1720

Query: 514  SSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSI 570
             +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS 
Sbjct: 1721 LALDVDR---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 1771

Query: 571  PPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKED 611
              E   S + Y S+F++LEE+ V  ++D+G                   R R  +  +ED
Sbjct: 1772 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 1831

Query: 612  QEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 671
            Q    PRLSRELLDEKGPEVLQDSL R YSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA
Sbjct: 1832 QNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 1891

Query: 672  VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPY 731
            VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPY
Sbjct: 1892 VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY 1951

Query: 732  SSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 791
            SSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS
Sbjct: 1952 SSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 2011

Query: 792  TPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 851
            TPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE
Sbjct: 2012 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 2071

Query: 852  GEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQH 911
            GEEDQNPPCPRL+  L++ + PEVLQDSLD  YSTPS   EL DS Q YRS FY  E+Q 
Sbjct: 2072 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQR 2131

Query: 912  ISFALYVD 919
            +  A+ +D
Sbjct: 2132 VGLAVDMD 2139



 Score =  564 bits (1453), Expect = e-160
 Identities = 372/795 (46%), Positives = 454/795 (57%), Gaps = 69/795 (8%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 2618 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 2677

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGP 278
            D  QP+ +   + EE  +   L VDR     E ++       P P  S   + +V     
Sbjct: 2678 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQG---PPCPRLSRELLEVVEPEVL 2734

Query: 279  LSS----EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEEC 334
              S         + LE  +  +P        F  L+EK     L      ++ K K    
Sbjct: 2735 QDSLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2790

Query: 335  KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSL 394
            +   K   R  ++ +E++     + + EL          E+E     E L++  D   S 
Sbjct: 2791 RRSKKERRRGRKEGEEDQNPPCPRLSREL--------LDEKE----PEVLQDSLDRCYST 2838

Query: 395  NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQ 454
                  L    +P  S    L+EQ         +L   L  +    D E+      E+ Q
Sbjct: 2839 PSGYLELPDLGQPYSSAVYSLEEQ---------YLGLALDVDRTKKDQEE------EEDQ 2883

Query: 455  KSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
                PR   E+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 2884 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 2943

Query: 512  -IGS----SSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDE 563
             +G         +R              E EE++ P  PR    L + +E EV Q+S D 
Sbjct: 2944 DVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDR 3003

Query: 564  GYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSREL 623
             YSTPS   E+    + YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSREL
Sbjct: 3004 CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSREL 3063

Query: 624  LDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY--- 680
            L+   PEVLQDSL RCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK    
Sbjct: 3064 LEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKG 3123

Query: 681  ----------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPEL 724
                            +E EEDQ+P CPRLSRELLDEKEPEVLQDSL R YSTPSGY EL
Sbjct: 3124 KKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 3183

Query: 725  PDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 784
            PDLGQPYSSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD
Sbjct: 3184 PDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 3243

Query: 785  SLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 844
            SLDRCYSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE
Sbjct: 3244 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 3303

Query: 845  RRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVF 904
            RRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS F
Sbjct: 3304 RRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF 3363

Query: 905  YSFEEQHISFALYVD 919
            Y  E+Q +  A+ +D
Sbjct: 3364 YVLEQQRVGLAVDMD 3378



 Score =  555 bits (1429), Expect = e-158
 Identities = 304/482 (63%), Positives = 344/482 (71%), Gaps = 36/482 (7%)

Query: 460  REMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 519
            RE+   +  EV +DSL+    T S      DS QP+R      E+ +V   +        
Sbjct: 2573 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 2625

Query: 520  REDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLA 576
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YSTPS   E+  
Sbjct: 2626 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2678

Query: 577  SYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSL 636
              + YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+   PEVLQDSL
Sbjct: 2679 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2738

Query: 637  YRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY---------------- 680
             RCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                 
Sbjct: 2739 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2798

Query: 681  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYS 737
               +E EEDQ+P CPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYS
Sbjct: 2799 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 2858

Query: 738  LEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 797
            LEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 2859 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2918

Query: 798  EQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 857
            EQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN
Sbjct: 2919 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2978

Query: 858  PPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALY 917
            PPCPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EEQ++  AL 
Sbjct: 2979 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3038

Query: 918  VD 919
            VD
Sbjct: 3039 VD 3040


>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
           sapiens]
          Length = 790

 Score = 1318 bits (3412), Expect = 0.0
 Identities = 678/765 (88%), Positives = 704/765 (92%), Gaps = 6/765 (0%)

Query: 90  EELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
           EE++QYKVLVHSQERELTQL+EKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15  EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 150 EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAI 209
           EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLES APREVQKAEESKV EDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 210 TCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATN 269
           TCSNSHGPCDS QPHKNIKITFEED+VNS+LVVDRESSHD CQDALNILPVPGPTSSATN
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATN 194

Query: 270 VSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKY 329
           VSMVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFR+LKEKCF+TQ+A FLA QQNKY
Sbjct: 195 VSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKY 254

Query: 330 KYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRD 389
           KYEECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRD
Sbjct: 255 KYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRD 314

Query: 390 ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEV 449
           ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDD+EDVQVEV
Sbjct: 315 ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV 374

Query: 450 AEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDS 509
           AEKVQKSS+PREMQKAEEKEVPEDSLEECAIT SNSHGPYDSNQPHRKTKITFEEDKVDS
Sbjct: 375 AEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDS 434

Query: 510 TLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTPS 569
           TLIGSSSHVE EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYST S
Sbjct: 435 TLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 494

Query: 570 IPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGP 629
           IPPE LASY+SYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK P
Sbjct: 495 IPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEP 554

Query: 630 EVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDP 689
           EVLQDSL RCYSTPS  L LTDSCQPYRSAFYVLEQQR+GLAVDMDEIEKYQEVEEDQDP
Sbjct: 555 EVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDP 614

Query: 690 SCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDL 749
           SCPRLSRELL EKEPEVLQDSL R YSTPSGY ELPDLGQPY SAVYSLEEQYLGLALD+
Sbjct: 615 SCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDV 674

Query: 750 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSS 809
           DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD     P   L       P    
Sbjct: 675 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLP-VVLNSLTPASPTEVP 733

Query: 810 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 854
           F    +  + F L   +++++G     RGR+  +E +R ++EGEE
Sbjct: 734 FMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKEEGEE 773



 Score =  447 bits (1151), Expect = e-125
 Identities = 287/569 (50%), Positives = 359/569 (63%), Gaps = 60/569 (10%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINEKL PQLAE KQQF +LKE+CF+TQ+A FLA +Q KYKY
Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKY 256

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQL+EKLREGRDAS
Sbjct: 257 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 316

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE  E
Sbjct: 317 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 376

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +S +PRE+QKAEE +V EDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL
Sbjct: 377 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 436

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           +    SSH E +DA++I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 437 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQES 485

Query: 301 -EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQ 359
            ++     ++  +    +LA + +     +  EE +  +   +   R    +++ ++ ++
Sbjct: 486 WDEGYSTLSIPPE----RLASYQSYSSTFHSLEEQQVCMAVDIGRHRW---DQVKKEDQE 538

Query: 360 AEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQL 419
           A   R  + L+  +E E+      L++  D   S       L    +P +S    L++  
Sbjct: 539 ATGPRLSRELLDEKEPEV------LQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQ-- 590

Query: 420 AEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLE 476
                      Q++    D D+ E  Q    E+ Q  S P   RE+   +E EV +DSL+
Sbjct: 591 -----------QRIGLAVDMDEIEKYQ--EVEEDQDPSCPRLSRELLAEKEPEVLQDSLD 637

Query: 477 ECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEE 536
            C  T S      D  QP+R    + EE       +G +  V+R          + D EE
Sbjct: 638 RCYSTPSGYLELPDLGQPYRSAVYSLEEQ-----YLGLALDVDR---------IKKDQEE 683

Query: 537 EEEKGPVSP---RNLQESEEEEVPQESWD 562
           EE++GP  P   R L E  E EV Q+S D
Sbjct: 684 EEDQGPPCPRLSRELLEVVEPEVLQDSLD 712



 Score =  223 bits (569), Expect = 5e-58
 Identities = 144/328 (43%), Positives = 186/328 (56%), Gaps = 39/328 (11%)

Query: 606 QVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQ 665
           +V ++ Q+++ PR   E+   +  EV +DSL  C  T S      DS QP+R      E+
Sbjct: 373 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 429

Query: 666 QRVGLAVD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 711
            +V   +               + E E   E EE++ P  PR    L + +E EV Q+S 
Sbjct: 430 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESW 486

Query: 712 GRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSR 771
              YST S  PE     Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSR
Sbjct: 487 DEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 546

Query: 772 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKG 831
           ELL+  EPEVLQDSLDRCYSTPS  L   DS QPY S+FY LE++ +G ++D+ EIEK  
Sbjct: 547 ELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY- 605

Query: 832 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYF 891
                             +E EEDQ+P CPRL+  L+  +EPEVLQDSLD CYSTPS Y 
Sbjct: 606 ------------------QEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYL 647

Query: 892 ELPDSFQHYRSVFYSFEEQHISFALYVD 919
           ELPD  Q YRS  YS EEQ++  AL VD
Sbjct: 648 ELPDLGQPYRSAVYSLEEQYLGLALDVD 675



 Score = 33.9 bits (76), Expect = 0.73
 Identities = 18/53 (33%), Positives = 31/53 (58%)

Query: 867 LMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
           + + EE +V +DSL+ C  T S      DS Q ++++  +FEE  ++ +L VD
Sbjct: 116 VQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVD 168


>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
          Length = 790

 Score = 1317 bits (3409), Expect = 0.0
 Identities = 677/765 (88%), Positives = 704/765 (92%), Gaps = 6/765 (0%)

Query: 90  EELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
           +E++QYKVLVHSQERELTQL+EKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15  QEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 150 EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAI 209
           EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLES APREVQKAEESKV EDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 210 TCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATN 269
           TCSNSHGPCDS QPHKNIKITFEED+VNS+LVVDRESSHD CQDALNILPVPGPTSSATN
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATN 194

Query: 270 VSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKY 329
           VSMVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFR+LKEKCF+TQ+A FLA QQNKY
Sbjct: 195 VSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKY 254

Query: 330 KYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRD 389
           KYEECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRD
Sbjct: 255 KYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRD 314

Query: 390 ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEV 449
           ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDD+EDVQVEV
Sbjct: 315 ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV 374

Query: 450 AEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDS 509
           AEKVQKSS+PREMQKAEEKEVPEDSLEECAIT SNSHGPYDSNQPHRKTKITFEEDKVDS
Sbjct: 375 AEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDS 434

Query: 510 TLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTPS 569
           TLIGSSSHVE EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYST S
Sbjct: 435 TLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 494

Query: 570 IPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGP 629
           IPPE LASY+SYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK P
Sbjct: 495 IPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEP 554

Query: 630 EVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDP 689
           EVLQDSL RCYSTPS  L LTDSCQPYRSAFYVLEQQR+GLAVDMDEIEKYQEVEEDQDP
Sbjct: 555 EVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDP 614

Query: 690 SCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDL 749
           SCPRLSRELL EKEPEVLQDSL R YSTPSGY ELPDLGQPY SAVYSLEEQYLGLALD+
Sbjct: 615 SCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDV 674

Query: 750 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSS 809
           DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD     P   L       P    
Sbjct: 675 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLP-VVLNSLTPASPTEVP 733

Query: 810 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 854
           F    +  + F L   +++++G     RGR+  +E +R ++EGEE
Sbjct: 734 FMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKEEGEE 773



 Score =  447 bits (1151), Expect = e-125
 Identities = 287/569 (50%), Positives = 359/569 (63%), Gaps = 60/569 (10%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINEKL PQLAE KQQF +LKE+CF+TQ+A FLA +Q KYKY
Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKY 256

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQL+EKLREGRDAS
Sbjct: 257 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 316

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE  E
Sbjct: 317 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 376

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +S +PRE+QKAEE +V EDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL
Sbjct: 377 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 436

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           +    SSH E +DA++I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 437 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQES 485

Query: 301 -EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQ 359
            ++     ++  +    +LA + +     +  EE +  +   +   R    +++ ++ ++
Sbjct: 486 WDEGYSTLSIPPE----RLASYQSYSSTFHSLEEQQVCMAVDIGRHRW---DQVKKEDQE 538

Query: 360 AEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQL 419
           A   R  + L+  +E E+      L++  D   S       L    +P +S    L++  
Sbjct: 539 ATGPRLSRELLDEKEPEV------LQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQ-- 590

Query: 420 AEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLE 476
                      Q++    D D+ E  Q    E+ Q  S P   RE+   +E EV +DSL+
Sbjct: 591 -----------QRIGLAVDMDEIEKYQ--EVEEDQDPSCPRLSRELLAEKEPEVLQDSLD 637

Query: 477 ECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEE 536
            C  T S      D  QP+R    + EE       +G +  V+R          + D EE
Sbjct: 638 RCYSTPSGYLELPDLGQPYRSAVYSLEEQ-----YLGLALDVDR---------IKKDQEE 683

Query: 537 EEEKGPVSP---RNLQESEEEEVPQESWD 562
           EE++GP  P   R L E  E EV Q+S D
Sbjct: 684 EEDQGPPCPRLSRELLEVVEPEVLQDSLD 712



 Score =  223 bits (569), Expect = 5e-58
 Identities = 144/328 (43%), Positives = 186/328 (56%), Gaps = 39/328 (11%)

Query: 606 QVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQ 665
           +V ++ Q+++ PR   E+   +  EV +DSL  C  T S      DS QP+R      E+
Sbjct: 373 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 429

Query: 666 QRVGLAVD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 711
            +V   +               + E E   E EE++ P  PR    L + +E EV Q+S 
Sbjct: 430 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESW 486

Query: 712 GRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSR 771
              YST S  PE     Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSR
Sbjct: 487 DEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 546

Query: 772 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKG 831
           ELL+  EPEVLQDSLDRCYSTPS  L   DS QPY S+FY LE++ +G ++D+ EIEK  
Sbjct: 547 ELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY- 605

Query: 832 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYF 891
                             +E EEDQ+P CPRL+  L+  +EPEVLQDSLD CYSTPS Y 
Sbjct: 606 ------------------QEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYL 647

Query: 892 ELPDSFQHYRSVFYSFEEQHISFALYVD 919
           ELPD  Q YRS  YS EEQ++  AL VD
Sbjct: 648 ELPDLGQPYRSAVYSLEEQYLGLALDVD 675



 Score = 33.9 bits (76), Expect = 0.73
 Identities = 18/53 (33%), Positives = 31/53 (58%)

Query: 867 LMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
           + + EE +V +DSL+ C  T S      DS Q ++++  +FEE  ++ +L VD
Sbjct: 116 VQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVD 168


>gi|157266285 hypothetical protein LOC728936 [Homo sapiens]
          Length = 670

 Score = 1288 bits (3333), Expect = 0.0
 Identities = 646/671 (96%), Positives = 655/671 (97%), Gaps = 1/671 (0%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKY 331
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLAN+Q KYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 391
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 392 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAE 451
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDD+EDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
           KVQKSSAPREMQKAEEKEVPEDSLEECAIT SNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 512 IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTPSIP 571
           IGSSSHVE EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYST SIP
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300

Query: 572 PEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631
           PEMLASY+SYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360

Query: 632 LQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSC 691
           LQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420

Query: 692 PRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDR 751
           PRLSRELLDEKEPEVLQDSL R YSTPS Y ELPDLGQPYSSAVYSLEEQYLGLALD+DR
Sbjct: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480

Query: 752 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFY 811
           IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QPYGSSFY
Sbjct: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540

Query: 812 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVE 871
           ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRLNGVLMEVE
Sbjct: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVE 599

Query: 872 EPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLH 931
           EPEVLQDSLD CYST SMYFELPDSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLH
Sbjct: 600 EPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLH 659

Query: 932 LVFQMEVIFPQ 942
           LVFQM VIFPQ
Sbjct: 660 LVFQMGVIFPQ 670



 Score =  541 bits (1393), Expect = e-153
 Identities = 345/700 (49%), Positives = 432/700 (61%), Gaps = 78/700 (11%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQF NLKE+CFLTQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE  E
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +S APRE+QKAEE +V EDSLEECAITCSNSHGP DSNQPHK  KITFEED+V+STL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           +    SSH E +DA++I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 241 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQES 289

Query: 301 -EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQ 359
            ++     ++  +     LA + +     +  EE +  +   +   R    +++ ++ ++
Sbjct: 290 WDEGYSTLSIPPE----MLASYQSYSSTFHSLEEQQVCMAVDIGRHRW---DQVKKEDQE 342

Query: 360 AEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQL 419
           A   R  + L+  +E E+      L++  D   S       L    +P +S    L++  
Sbjct: 343 ATGPRLSRELLDEKEPEV------LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ-- 394

Query: 420 AEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLE 476
                      Q++    D D+ E  Q    E+ Q  S P   RE+   +E EV +DSL+
Sbjct: 395 -----------QRVGLAIDMDEIEKYQ--EVEEDQDPSCPRLSRELLDEKEPEVLQDSLD 441

Query: 477 ECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEE 536
            C  T S+     D  QP+     + EE       +G +  V+R          + D EE
Sbjct: 442 RCYSTPSDYLELPDLGQPYSSAVYSLEEQ-----YLGLALDVDR---------IKKDQEE 487

Query: 537 EEEKGPVSP---RNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQV 593
           EE++GP  P   R L E  E EV Q+S D  YSTPS   E   S + Y S+F++LEE+ V
Sbjct: 488 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHV 547

Query: 594 CMAVDIG------------------RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDS 635
             ++D+G                  + R  + + ED     PRL+  L++ + PEVLQDS
Sbjct: 548 GFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEEPEVLQDS 607

Query: 636 LYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675
           L RCYST S   EL DS Q YRS FY  E++ +  A+ +D
Sbjct: 608 LDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647


>gi|29789405 hypothetical protein LOC284565 [Homo sapiens]
          Length = 670

 Score = 1283 bits (3319), Expect = 0.0
 Identities = 644/671 (95%), Positives = 653/671 (97%), Gaps = 1/671 (0%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKY 331
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLAN+Q KYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 391
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 392 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAE 451
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDD+EDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
           KVQKSSAPREMQKAEEKEVPEDSLEECAIT SNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 512 IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTPSIP 571
           IGSSSHVE EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYST SIP
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300

Query: 572 PEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631
           PEMLASY+SYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360

Query: 632 LQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSC 691
           LQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420

Query: 692 PRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDR 751
           PRLSRELLDEKEPEVLQDSL R YSTPS Y ELPDLGQPYSSAVYSLEEQYLGLAL +DR
Sbjct: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480

Query: 752 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFY 811
           IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QPYGSSFY
Sbjct: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540

Query: 812 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVE 871
           ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL GVLMEVE
Sbjct: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVE 599

Query: 872 EPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLH 931
           EPEVLQDSLD CYSTPSMYFE PDSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLH
Sbjct: 600 EPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLH 659

Query: 932 LVFQMEVIFPQ 942
           LVFQM VIFPQ
Sbjct: 660 LVFQMGVIFPQ 670



 Score =  540 bits (1391), Expect = e-153
 Identities = 345/700 (49%), Positives = 431/700 (61%), Gaps = 78/700 (11%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQF NLKE+CFLTQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE  E
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +S APRE+QKAEE +V EDSLEECAITCSNSHGP DSNQPHK  KITFEED+V+STL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           +    SSH E +DA++I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 241 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQES 289

Query: 301 -EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQ 359
            ++     ++  +     LA + +     +  EE +  +   +   R    +++ ++ ++
Sbjct: 290 WDEGYSTLSIPPE----MLASYQSYSSTFHSLEEQQVCMAVDIGRHRW---DQVKKEDQE 342

Query: 360 AEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQL 419
           A   R  + L+  +E E+      L++  D   S       L    +P +S    L++  
Sbjct: 343 ATGPRLSRELLDEKEPEV------LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ-- 394

Query: 420 AEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLE 476
                      Q++    D D+ E  Q    E+ Q  S P   RE+   +E EV +DSL+
Sbjct: 395 -----------QRVGLAIDMDEIEKYQ--EVEEDQDPSCPRLSRELLDEKEPEVLQDSLD 441

Query: 477 ECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEE 536
            C  T S+     D  QP+     + EE       +G +  V+R          + D EE
Sbjct: 442 RCYSTPSDYLELPDLGQPYSSAVYSLEEQ-----YLGLALAVDR---------IKKDQEE 487

Query: 537 EEEKGPVSP---RNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQV 593
           EE++GP  P   R L E  E EV Q+S D  YSTPS   E   S + Y S+F++LEE+ V
Sbjct: 488 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHV 547

Query: 594 CMAVDIG------------------RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDS 635
             ++D+G                  + R  + + ED     PRL   L++ + PEVLQDS
Sbjct: 548 GFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEEPEVLQDS 607

Query: 636 LYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675
           L RCYSTPS   E  DS Q YRS FY  E++ +  A+ +D
Sbjct: 608 LDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647


>gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo
           sapiens]
          Length = 3815

 Score = 1230 bits (3182), Expect = 0.0
 Identities = 616/661 (93%), Positives = 631/661 (95%)

Query: 259 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL 318
           PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFRNLKE+CF+TQL
Sbjct: 8   PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQL 67

Query: 319 AGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 378
           AGFLANQQ KYKYEECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT
Sbjct: 68  AGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 127

Query: 379 QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438
           QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND
Sbjct: 128 QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 187

Query: 439 NDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKT 498
           NDD+EDVQVE+AEKVQKSSAPREMQKAEEKEVPEDS EECAITYSNSHGPYDSNQPHRKT
Sbjct: 188 NDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKT 247

Query: 499 KITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 558
           KITFEEDKVDSTLIGSSSHVE EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ
Sbjct: 248 KITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 307

Query: 559 ESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPR 618
           ESWDEGYST SIPPEMLASY+SYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPR
Sbjct: 308 ESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPR 367

Query: 619 LSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 678
           LSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQR+GLAVDMDEIE
Sbjct: 368 LSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMDEIE 427

Query: 679 KYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSL 738
           KYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYSL
Sbjct: 428 KYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSL 487

Query: 739 EEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLE 798
           EEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLE
Sbjct: 488 EEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLE 547

Query: 799 QPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNP 858
           QPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNP
Sbjct: 548 QPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNP 607

Query: 859 PCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYV 918
           PCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+Q +  A+ +
Sbjct: 608 PCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM 667

Query: 919 D 919
           D
Sbjct: 668 D 668



 Score = 1020 bits (2637), Expect = 0.0
 Identities = 586/954 (61%), Positives = 659/954 (69%), Gaps = 97/954 (10%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINEKL PQLAE KQQF NLKERCF+TQLAGFLAN+QKKYKY
Sbjct: 21  MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFLANQQKKYKY 80

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRDAS
Sbjct: 81  EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 140

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE  E
Sbjct: 141 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAE 200

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +S APRE+QKAEE +V EDS EECAIT SNSHGP DSNQPH+  KITFEED+V+STL
Sbjct: 201 KVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 260

Query: 241 VVDRESSHDECQDALNILPV----------PGPTSSATNVSMVVSAGPLSSEKAEMNILE 290
           +    SSH E +DA++I+P            GP S            P  S     + L 
Sbjct: 261 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 318

Query: 291 INEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKE 350
           I  ++          F +L+E+         +A    ++++++ K             KE
Sbjct: 319 IPPEMLASYQSYSSTFHSLEEQQVC------MAVDIGRHRWDQVK-------------KE 359

Query: 351 EKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKS 410
           ++ A   + + EL   K              E L++  D   S       L    +P +S
Sbjct: 360 DQEATGPRLSRELLDEKG------------PEVLQDSLDRCYSTPSGCLELTDSCQPYRS 407

Query: 411 QGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEE 467
               L++Q             ++    D D+ E  Q    E+ Q  S PR   E+   +E
Sbjct: 408 AFYVLEQQ-------------RIGLAVDMDEIEKYQE--VEEDQDPSCPRLSRELLDEKE 452

Query: 468 KEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHII 527
            EV +DSL+ C  T S      D  QP+     + EE       +G +  V+R       
Sbjct: 453 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALDVDR------- 500

Query: 528 PENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSST 584
              + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E   S + Y S+
Sbjct: 501 --TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 558

Query: 585 FHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGPRLSRELLD 625
           F++LEE+ V  ++D+G                   R R  +  +EDQ    PRLSRELLD
Sbjct: 559 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLD 618

Query: 626 EKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEE 685
           EKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEE
Sbjct: 619 EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEE 678

Query: 686 DQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGL 745
           DQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYSLEEQYLGL
Sbjct: 679 DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 738

Query: 746 ALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQP 805
           ALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QP
Sbjct: 739 ALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 798

Query: 806 YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNG 865
           YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+ 
Sbjct: 799 YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 858

Query: 866 VLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
            L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EEQ++  AL VD
Sbjct: 859 ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 912



 Score =  628 bits (1619), Expect = e-180
 Identities = 400/790 (50%), Positives = 470/790 (59%), Gaps = 78/790 (9%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 1898 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1957

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGP 278
            D  QP+ +   + EE  +   L VDR     E ++       P P  S   + +V     
Sbjct: 1958 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQG---PPCPRLSRELLEVVEPEVL 2014

Query: 279  LSS----EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEEC 334
              S         + LE  +  +P        F  L+EK     L      ++ K K    
Sbjct: 2015 QDSLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2070

Query: 335  KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSL 394
            +   K   R  ++ +E++     + + EL   K              E L++  D S S 
Sbjct: 2071 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRSYST 2118

Query: 395  NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQ 454
                  L    +P +S    L++Q             ++    D D+ E  Q    E+ Q
Sbjct: 2119 PSGCLELTDSCQPYRSAFYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQ 2163

Query: 455  KSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
              S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE       
Sbjct: 2164 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----Y 2218

Query: 512  IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTP 568
            +G +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTP
Sbjct: 2219 LGLALDVDR---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 2269

Query: 569  SIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKK 609
            S   E   S + Y S+F++LEE+ V  ++D+G                   R R  +  +
Sbjct: 2270 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 2329

Query: 610  EDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 669
            EDQ    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG
Sbjct: 2330 EDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 2389

Query: 670  LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQ 729
            LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQ
Sbjct: 2390 LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 2449

Query: 730  PYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 789
            PYSSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC
Sbjct: 2450 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 2509

Query: 790  YSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 849
            YSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR
Sbjct: 2510 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 2569

Query: 850  KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909
            KEGEEDQNPPCPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE
Sbjct: 2570 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 2629

Query: 910  QHISFALYVD 919
            Q++  AL VD
Sbjct: 2630 QYLGLALDVD 2639



 Score =  614 bits (1584), Expect = e-175
 Identities = 394/790 (49%), Positives = 466/790 (58%), Gaps = 78/790 (9%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 1654 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1713

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGP 278
            D  QP+ +   + EE  +   L VDR     E ++       P P  S   + +V     
Sbjct: 1714 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQG---PPCPRLSRELLEVVEPEVL 1770

Query: 279  LSS----EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEEC 334
              S         + LE  +  +P        F  L+EK     L      ++ K K    
Sbjct: 1771 QDSLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1826

Query: 335  KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSL 394
            +   K   R  ++ +E++     + + EL   K              E L++  D   S 
Sbjct: 1827 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRCYST 1874

Query: 395  NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQ 454
                  L    +P +S    L++             Q++    D D+ E  Q    E+ Q
Sbjct: 1875 PSGCLELTDSCQPYRSAFYVLEQ-------------QRVGLAVDMDEIEKYQ--EVEEDQ 1919

Query: 455  KSSAP---REMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
              S P   RE+   +E EV +DSL+ C  T S      D  QP+     + EE       
Sbjct: 1920 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----Y 1974

Query: 512  IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTP 568
            +G +  V+R          + D EEEE++GP  P   R L E  E EV Q+S D  YSTP
Sbjct: 1975 LGLALDVDR---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 2025

Query: 569  SIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKK 609
            S   E   S + Y S+F++LEE+ V  ++D+G                   R R  +  +
Sbjct: 2026 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 2085

Query: 610  EDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 669
            EDQ    PRLSRELLDEKGPEVLQDSL R YSTPSGCLELTDSCQPYRSAFYVLEQQRVG
Sbjct: 2086 EDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 2145

Query: 670  LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQ 729
            LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQ
Sbjct: 2146 LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 2205

Query: 730  PYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 789
            PYSSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC
Sbjct: 2206 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 2265

Query: 790  YSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 849
            YSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR
Sbjct: 2266 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 2325

Query: 850  KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909
            KEGEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+
Sbjct: 2326 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 2385

Query: 910  QHISFALYVD 919
            Q +  A+ +D
Sbjct: 2386 QRVGLAVDMD 2395



 Score =  613 bits (1581), Expect = e-175
 Identities = 331/482 (68%), Positives = 361/482 (74%), Gaps = 36/482 (7%)

Query: 460  REMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 519
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE       +G +  V+
Sbjct: 2585 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALDVD 2639

Query: 520  REDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLA 576
            R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E   
Sbjct: 2640 R---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 2690

Query: 577  SYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 617
            S + Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ    P
Sbjct: 2691 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 2750

Query: 618  RLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 677
            RLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI
Sbjct: 2751 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 2810

Query: 678  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYS 737
            EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYS
Sbjct: 2811 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 2870

Query: 738  LEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 797
            LEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 2871 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2930

Query: 798  EQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 857
            EQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN
Sbjct: 2931 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2990

Query: 858  PPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALY 917
            PPCPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EEQ++  AL 
Sbjct: 2991 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3050

Query: 918  VD 919
            VD
Sbjct: 3051 VD 3052



 Score =  609 bits (1571), Expect = e-174
 Identities = 387/773 (50%), Positives = 460/773 (59%), Gaps = 76/773 (9%)

Query: 177  EEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEE 233
            +E E+    P PR   E+   +E +V +DSL+ C  T S      D  QP+ +   + EE
Sbjct: 1425 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1484

Query: 234  DEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNV--SMVVSAGPLSSEKAEMNILEI 291
              +   L VDR +  D+ ++     P P  +     V    V+            + LE 
Sbjct: 1485 QYLGLALDVDR-TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 1543

Query: 292  NEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEE 351
             +  +P        F  L+EK     L      ++ K K    +   K   R  ++ +E+
Sbjct: 1544 PDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 1599

Query: 352  KLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQ 411
            +     + + EL   K              E L++  D   S       L    +P +S 
Sbjct: 1600 QNPPCPRLSRELLDEKG------------PEVLQDSLDRCYSTPSGCLELTDSCQPYRSA 1647

Query: 412  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEEK 468
               L++Q             ++    D D+ E  Q    E+ Q  S PR   E+   +E 
Sbjct: 1648 FYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQDPSCPRLSRELLDEKEP 1692

Query: 469  EVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIP 528
            EV +DSL+ C  T S      D  QP+     + EE       +G +  V+R        
Sbjct: 1693 EVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALDVDR-------- 1739

Query: 529  ENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTF 585
              + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E   S + Y S+F
Sbjct: 1740 -TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 1798

Query: 586  HSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGPRLSRELLDE 626
            ++LEE+ V  ++D+G                   R R  +  +EDQ    PRLSRELLDE
Sbjct: 1799 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 1858

Query: 627  KGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED 686
            KGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED
Sbjct: 1859 KGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED 1918

Query: 687  QDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLA 746
            QDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYSLEEQYLGLA
Sbjct: 1919 QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 1978

Query: 747  LDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPY 806
            LD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QPY
Sbjct: 1979 LDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2038

Query: 807  GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGV 866
            GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+  
Sbjct: 2039 GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE 2098

Query: 867  LMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
            L++ + PEVLQDSLD  YSTPS   EL DS Q YRS FY  E+Q +  A+ +D
Sbjct: 2099 LLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 2151



 Score =  608 bits (1568), Expect = e-174
 Identities = 328/494 (66%), Positives = 364/494 (73%), Gaps = 36/494 (7%)

Query: 460  REMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 519
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE       +G +  V+
Sbjct: 3336 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALDVD 3390

Query: 520  REDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLA 576
            R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E   
Sbjct: 3391 R---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 3441

Query: 577  SYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 617
            S + Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ    P
Sbjct: 3442 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 3501

Query: 618  RLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 677
            RLSRELLDEKGPEVLQDSL R YSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI
Sbjct: 3502 RLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 3561

Query: 678  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYS 737
            EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYS
Sbjct: 3562 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 3621

Query: 738  LEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 797
            LEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 3622 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 3681

Query: 798  EQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 857
            EQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN
Sbjct: 3682 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3741

Query: 858  PPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALY 917
            PPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+Q +  A+ 
Sbjct: 3742 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 3801

Query: 918  VDNRFFTLTVTSLH 931
            +D  + ++ V  +H
Sbjct: 3802 MDGEYLSMKVIRIH 3815



 Score =  594 bits (1532), Expect = e-169
 Identities = 385/788 (48%), Positives = 461/788 (58%), Gaps = 74/788 (9%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 415  QRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 474

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNV--SMVVSA 276
            D  QP+ +   + EE  +   L VDR +  D+ ++     P P  +     V    V+  
Sbjct: 475  DLGQPYSSAVYSLEEQYLGLALDVDR-TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 533

Query: 277  GPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKD 336
                      + LE  +  +P        F  L+EK     L      ++ K K    + 
Sbjct: 534  SLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 589

Query: 337  LIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNE 396
              K   R  ++ +E++     + + EL   K              E L++  D   S   
Sbjct: 590  SKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRCYSTPS 637

Query: 397  HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKS 456
                L    +P +S    L++Q             ++    D D+ E  Q    E+ Q  
Sbjct: 638  GCLELTDSCQPYRSAFYVLEQQ-------------RVGLAVDMDEIEKYQE--VEEDQDP 682

Query: 457  SAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIG 513
            S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE       +G
Sbjct: 683  SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLG 737

Query: 514  SSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSI 570
             +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS 
Sbjct: 738  LALDVDR---------TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 788

Query: 571  PPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKED 611
              E   S + Y S+F++LEE+ V  ++D+G                   R R  +  +ED
Sbjct: 789  CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 848

Query: 612  QEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 671
            Q    PRLSRELLDEK PEVLQDSL RCYSTPSG LEL D  QPY SA Y LE+Q +GLA
Sbjct: 849  QNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 908

Query: 672  VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPY 731
            +D+DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPY
Sbjct: 909  LDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY 968

Query: 732  SSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 791
            SSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS
Sbjct: 969  SSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 1028

Query: 792  TPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 851
            TPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE
Sbjct: 1029 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1088

Query: 852  GEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQH 911
            GEEDQNPPCPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EEQ+
Sbjct: 1089 GEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 1148

Query: 912  ISFALYVD 919
            +  AL VD
Sbjct: 1149 LGLALDVD 1156



 Score =  567 bits (1461), Expect = e-161
 Identities = 366/788 (46%), Positives = 450/788 (57%), Gaps = 71/788 (9%)

Query: 169  DEDEDVQVEEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225
            D D   + +E+E+    P PR   E+ +  E +V +DSL+ C  T S+     DS QP+ 
Sbjct: 741  DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 800

Query: 226  NIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 285
            +     EE  V  +L V       + +                        G  S ++  
Sbjct: 801  SSFYALEEKHVGFSLDVGEIEKKGKGKKR---------------------RGRRSKKERR 839

Query: 286  MNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNE 345
                E  E   P      ++  + KE   L        +  + Y   E  DL +      
Sbjct: 840  RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL--ELPDLGQPYSSAV 897

Query: 346  RQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTP- 404
               +E+ L   L   +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP 
Sbjct: 898  YSLEEQYLGLAL-DVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS 956

Query: 405  ---DEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR- 460
               + PD  Q         E     Q+L   L  +    D E+      E+ Q    PR 
Sbjct: 957  GYLELPDLGQPYSSAVYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRL 1006

Query: 461  --EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL-IGS--- 514
              E+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L +G    
Sbjct: 1007 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK 1066

Query: 515  -SSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSI 570
                 +R              E EE++ P  PR    L + +E EV Q+S D  YSTPS 
Sbjct: 1067 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 1126

Query: 571  PPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPE 630
              E+    + YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+   PE
Sbjct: 1127 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPE 1186

Query: 631  VLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY---------- 680
            VLQDSL RCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK           
Sbjct: 1187 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 1246

Query: 681  ---------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPY 731
                     +E EEDQ+P CPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPY
Sbjct: 1247 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY 1306

Query: 732  SSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 791
            SSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS
Sbjct: 1307 SSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 1366

Query: 792  TPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 851
            TPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE
Sbjct: 1367 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1426

Query: 852  GEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQH 911
            GEEDQNPPCPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EEQ+
Sbjct: 1427 GEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 1486

Query: 912  ISFALYVD 919
            +  AL VD
Sbjct: 1487 LGLALDVD 1494



 Score =  564 bits (1454), Expect = e-160
 Identities = 364/790 (46%), Positives = 454/790 (57%), Gaps = 75/790 (9%)

Query: 169  DEDEDVQVEEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225
            D D   + +E+E+    P PR   E+ +  E +V +DSL+ C  T S+     DS QP+ 
Sbjct: 2637 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2696

Query: 226  NIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 285
            +     EE  V  +L V       +           G              G    E+ +
Sbjct: 2697 SSFYALEEKHVGFSLDVGEIEKKGK-----------GKKRRGRRSKKERRRGRKEGEEDQ 2745

Query: 286  MNILEINEKLRPQLAEKK--QQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLR 343
                    +L  +L ++K  +  ++  ++C+ T  +G L    +   Y           R
Sbjct: 2746 NPPCP---RLSRELLDEKGPEVLQDSLDRCYSTP-SGCLELTDSCQPY-----------R 2790

Query: 344  NERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLT 403
            +     E++        +E+ +Y+ +   Q+    +L  +L + ++     +   +   T
Sbjct: 2791 SAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYST 2850

Query: 404  P----DEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAP 459
            P    + PD  Q         E     Q+L   L  +    D E+      E+ Q    P
Sbjct: 2851 PSGYLELPDLGQPYSSAVYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCP 2900

Query: 460  R---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL-IGS- 514
            R   E+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L +G  
Sbjct: 2901 RLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEI 2960

Query: 515  ---SSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTP 568
                   +R              E EE++ P  PR    L + +E EV Q+S D  YSTP
Sbjct: 2961 EKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTP 3020

Query: 569  SIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKG 628
            S   E+    + YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+   
Sbjct: 3021 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3080

Query: 629  PEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY-------- 680
            PEVLQDSL RCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK         
Sbjct: 3081 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3140

Query: 681  -----------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQ 729
                       +E EEDQ+P CPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQ
Sbjct: 3141 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 3200

Query: 730  PYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 789
            PYSSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC
Sbjct: 3201 PYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 3260

Query: 790  YSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 849
            YSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR
Sbjct: 3261 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 3320

Query: 850  KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909
            KEGEEDQNPPCPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE
Sbjct: 3321 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3380

Query: 910  QHISFALYVD 919
            Q++  AL VD
Sbjct: 3381 QYLGLALDVD 3390



 Score =  563 bits (1452), Expect = e-160
 Identities = 371/788 (47%), Positives = 451/788 (57%), Gaps = 69/788 (8%)

Query: 167  DEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 910  DVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 969

Query: 226  NIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSS---- 281
            +   + EE  +   L VDR     E ++       P P  S   + +V       S    
Sbjct: 970  SAVYSLEEQYLGLALDVDRTKKDQEEEEDQG---PPCPRLSRELLEVVEPEVLQDSLDRC 1026

Query: 282  EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFM 341
                 + LE  +  +P        F  L+EK     L      ++ K K    +   K  
Sbjct: 1027 YSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKER 1082

Query: 342  LRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQAL 401
             R  ++ +E++     + + EL          E+E     E L++  D   S       L
Sbjct: 1083 RRGRKEGEEDQNPPCPRLSREL--------LDEKE----PEVLQDSLDRCYSTPSGYLEL 1130

Query: 402  LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR- 460
                +P  S    L+EQ         +L   L  +    D E+      E+ Q    PR 
Sbjct: 1131 PDLGQPYSSAVYSLEEQ---------YLGLALDVDRTKKDQEE------EEDQGPPCPRL 1175

Query: 461  --EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL-IGS--- 514
              E+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L +G    
Sbjct: 1176 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK 1235

Query: 515  -SSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSI 570
                 +R              E EE++ P  PR    L + +E EV Q+S D  YSTPS 
Sbjct: 1236 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 1295

Query: 571  PPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPE 630
              E+    + YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+   PE
Sbjct: 1296 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPE 1355

Query: 631  VLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY---------- 680
            VLQDSL RCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK           
Sbjct: 1356 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 1415

Query: 681  ---------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPY 731
                     +E EEDQ+P CPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPY
Sbjct: 1416 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY 1475

Query: 732  SSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 791
            SSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS
Sbjct: 1476 SSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 1535

Query: 792  TPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 851
            TPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE
Sbjct: 1536 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1595

Query: 852  GEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQH 911
            GEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+Q 
Sbjct: 1596 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 1655

Query: 912  ISFALYVD 919
            +  A+ +D
Sbjct: 1656 VGLAVDMD 1663



 Score =  560 bits (1443), Expect = e-159
 Identities = 371/795 (46%), Positives = 453/795 (56%), Gaps = 69/795 (8%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 2799 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 2858

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGP 278
            D  QP+ +   + EE  +   L VDR     E ++       P P  S   + +V     
Sbjct: 2859 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQG---PPCPRLSRELLEVVEPEVL 2915

Query: 279  LSS----EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEEC 334
              S         + LE  +  +P        F  L+EK     L      ++ K K    
Sbjct: 2916 QDSLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2971

Query: 335  KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSL 394
            +   K   R  ++ +E++     + + EL          E+E     E L++  D   S 
Sbjct: 2972 RRSKKERRRGRKEGEEDQNPPCPRLSREL--------LDEKE----PEVLQDSLDRCYST 3019

Query: 395  NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQ 454
                  L    +P  S    L+EQ         +L   L  +    D E+      E+ Q
Sbjct: 3020 PSGYLELPDLGQPYSSAVYSLEEQ---------YLGLALDVDRTKKDQEE------EEDQ 3064

Query: 455  KSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
                PR   E+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 3065 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 3124

Query: 512  -IGS----SSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDE 563
             +G         +R              E EE++ P  PR    L + +E EV Q+S D 
Sbjct: 3125 DVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDR 3184

Query: 564  GYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSREL 623
             YSTPS   E+    + YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSREL
Sbjct: 3185 CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSREL 3244

Query: 624  LDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY--- 680
            L+   PEVLQDSL RCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK    
Sbjct: 3245 LEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKG 3304

Query: 681  ----------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPEL 724
                            +E EEDQ+P CPRLSRELLDEKEPEVLQDSL R YSTPSGY EL
Sbjct: 3305 KKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 3364

Query: 725  PDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 784
            PDLGQPYSSAVYSLEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD
Sbjct: 3365 PDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 3424

Query: 785  SLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 844
            SLDRCYSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE
Sbjct: 3425 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 3484

Query: 845  RRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVF 904
            RRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSLD  YSTPS   EL DS Q YRS F
Sbjct: 3485 RRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAF 3544

Query: 905  YSFEEQHISFALYVD 919
            Y  E+Q +  A+ +D
Sbjct: 3545 YVLEQQRVGLAVDMD 3559



 Score =  551 bits (1419), Expect = e-156
 Identities = 301/482 (62%), Positives = 343/482 (71%), Gaps = 36/482 (7%)

Query: 460  REMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 519
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 2341 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 2393

Query: 520  REDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLA 576
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YSTPS   E+  
Sbjct: 2394 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2446

Query: 577  SYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSL 636
              + YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+   PEVLQDSL
Sbjct: 2447 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2506

Query: 637  YRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY---------------- 680
             RCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                 
Sbjct: 2507 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2566

Query: 681  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYS 737
               +E EEDQ+P CPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYS
Sbjct: 2567 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 2626

Query: 738  LEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 797
            LEEQYLGLALD+DR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 2627 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2686

Query: 798  EQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 857
            EQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN
Sbjct: 2687 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2746

Query: 858  PPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALY 917
            PPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+Q +  A+ 
Sbjct: 2747 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 2806

Query: 918  VD 919
            +D
Sbjct: 2807 MD 2808



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 1/92 (1%)

Query: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 3550 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 3609

Query: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDE 250
            D  QP+ +   + EE  +   L VDR     E
Sbjct: 3610 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQE 3641



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 46/176 (26%), Positives = 71/176 (40%), Gaps = 27/176 (15%)

Query: 79   EEKLAEQLKQAEELRQYKVLVHSQE-------RELTQLKEK--LREGRDASRSLNEHLQA 129
            EE+        +E+ +Y+ +   Q+       REL   KE   L++  D   S       
Sbjct: 901  EEQYLGLALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLE 960

Query: 130  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPR 189
            L    +P  S    L+EQ   G  L    V +   + +E+ED+             P PR
Sbjct: 961  LPDLGQPYSSAVYSLEEQYL-GLALD---VDRTKKDQEEEEDQG-----------PPCPR 1005

Query: 190  ---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVV 242
               E+ +  E +V +DSL+ C  T S+     DS QP+ +     EE  V  +L V
Sbjct: 1006 LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1061



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)

Query: 169  DEDEDVQVEEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225
            D D   + +E+E+    P PR   E+ +  E +V +DSL+ C  T S+     DS QP+ 
Sbjct: 3632 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3691

Query: 226  NIKITFEEDEVNSTLVV 242
            +     EE  V  +L V
Sbjct: 3692 SSFYALEEKHVGFSLDV 3708



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 3/72 (4%)

Query: 177  EEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEE 233
            +E E+    P PR   E+   +  +V +DSL+ C  T S      DS QP+++     E+
Sbjct: 3734 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 3793

Query: 234  DEVNSTLVVDRE 245
              V   + +D E
Sbjct: 3794 QRVGLAVDMDGE 3805


>gi|7657017 hypothetical protein LOC25832 [Homo sapiens]
          Length = 921

 Score = 1081 bits (2796), Expect = 0.0
 Identities = 542/579 (93%), Positives = 553/579 (95%)

Query: 341 MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 400
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60

Query: 401 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR 460
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDD+EDVQVEVAEKVQKSSAPR
Sbjct: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120

Query: 461 EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVER 520
           EMQKAEEKEVPEDSLEECAIT SNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 
Sbjct: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180

Query: 521 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKS 580
           EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYST SIPPEMLASYKS
Sbjct: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240

Query: 581 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCY 640
           YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEKGPEVLQDSL RCY
Sbjct: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300

Query: 641 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 700
           STPSGCLELTDSCQPYRSAFYVLEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360

Query: 701 EKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEE 760
           EKEPEVLQDSLGR YSTPSGY ELPDLGQPYSSAVYSLEEQYLGLALD+DRIKKDQEEEE
Sbjct: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420

Query: 761 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGF 820
           DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QPYGSSFYALEEKHVGF
Sbjct: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480

Query: 821 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSL 880
           SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSL
Sbjct: 481 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540

Query: 881 DGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919
           D CYSTPS   EL DS Q YRS FY  E+Q +  A+ +D
Sbjct: 541 DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMD 579



 Score =  985 bits (2547), Expect = 0.0
 Identities = 568/929 (61%), Positives = 644/929 (69%), Gaps = 64/929 (6%)

Query: 70  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQA 129
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRDASRSLNEHLQA
Sbjct: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60

Query: 130 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPR 189
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE  EKV +S APR
Sbjct: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120

Query: 190 EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHD 249
           E+QKAEE +V EDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL+    SSH 
Sbjct: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHV 178

Query: 250 ECQDALNILPV----------PGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQL 299
           E +DA++I+P            GP S            P  S     + L I  ++    
Sbjct: 179 EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY 238

Query: 300 AEKKQQFRNLKEK--CFLTQLAGFLANQQNKYKYEECKDLIKFMLRNER--QFKEEKL-- 353
                 F +L+E+  C    +     +Q  K  +E     +   L +E+  +  ++ L  
Sbjct: 239 KSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDR 298

Query: 354 -----AEQLKQAEELRQYKVLVHAQERELTQLR------EKLRE-GRDASRSLNEHLQAL 401
                +  L+  +  + Y+   +  E++   L       EK +E   D   S     + L
Sbjct: 299 CYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSREL 358

Query: 402 LTPDEPDKSQGQ---------------DLQEQLAEGCRLA--QHLVQKLSPENDNDDNED 444
           L   EP+  Q                 DL +  +        Q+L   L  +    D E+
Sbjct: 359 LDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEE 418

Query: 445 VQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKIT 501
                 E+ Q    PR   E+ +  E EV +DSL+ C  T S+     DS QP+  +   
Sbjct: 419 ------EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYA 472

Query: 502 FEEDKVDSTL-IGS----SSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE-- 554
            EE  V  +L +G         +R              E EE++ P  PR  +E  +E  
Sbjct: 473 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG 532

Query: 555 -EVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQE 613
            EV Q+S D  YSTPS   E+  S + Y S F+ LE+Q+V +AVD+      Q  +EDQ+
Sbjct: 533 PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQD 592

Query: 614 ATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 673
            + PRLS ELLDEK PEVLQ+SL RCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAVD
Sbjct: 593 PSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 652

Query: 674 MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSS 733
           MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGR YSTPSGY ELPDLGQPYSS
Sbjct: 653 MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSS 712

Query: 734 AVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 793
           AVYSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP
Sbjct: 713 AVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 772

Query: 794 SSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 853
           SSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE
Sbjct: 773 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 832

Query: 854 EDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHIS 913
           EDQNPPCPRLN +LMEVEEPEVLQDSLD CYSTPSMYFELPDSFQHYRSVFYSFEE+HIS
Sbjct: 833 EDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHIS 892

Query: 914 FALYVDNRFFTLTVTSLHLVFQMEVIFPQ 942
           FALYVDNRFFTLTVTSLHLVFQM VIFPQ
Sbjct: 893 FALYVDNRFFTLTVTSLHLVFQMGVIFPQ 921


>gi|14149997 neuroblastoma breakpoint family, member 3 [Homo
           sapiens]
          Length = 633

 Score =  828 bits (2140), Expect = 0.0
 Identities = 428/577 (74%), Positives = 481/577 (83%), Gaps = 4/577 (0%)

Query: 248 HDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR 307
           H E +D      VPGPTSSATNVSMVVSAGP S EKAEMNILEIN+K RPQLAE KQQFR
Sbjct: 37  HQELRDPT----VPGPTSSATNVSMVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFR 92

Query: 308 NLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYK 367
           NLK+KC +TQ+A FLAN+QN Y YE+CKDLIK MLR+ER   EEKLAE+L QAEELRQYK
Sbjct: 93  NLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYK 152

Query: 368 VLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQ 427
           VLVH+QERELTQLREKL+EGRDASRSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRLAQ
Sbjct: 153 VLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQ 212

Query: 428 HLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHG 487
           HLVQKLSPEND+D++EDV+VE AEKVQ+  APRE+QKAEEKEVPEDSLEECAIT SNSH 
Sbjct: 213 HLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHH 272

Query: 488 PYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRN 547
           P +SNQP+  T+ITFEED+VDSTLI SSSH E  DAV IIPENESD E+EEEKGPVSPRN
Sbjct: 273 PCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRN 332

Query: 548 LQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQV 607
           LQESEEEE PQESWDEG  T SIPP+M ASY+S  STFHS+EEQQV +A+DIGRH  DQV
Sbjct: 333 LQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQV 392

Query: 608 KKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 667
           KKEDQEAT PRLSRELLDEK PEVLQDSL R YSTP   LEL D CQPYRS FY L++Q 
Sbjct: 393 KKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQH 452

Query: 668 VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDL 727
           +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSL RWYSTP  YPELPD 
Sbjct: 453 LGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDS 512

Query: 728 GQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 787
            QPY S  YSLEE+++G +LD+D I+K QE EEDQ PPCPRL+  L+E  EPEVLQDSLD
Sbjct: 513 CQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLD 572

Query: 788 RCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDV 824
           RCYST S+  +   S+Q Y S+FY+ EE+ V  +LDV
Sbjct: 573 RCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  451 bits (1160), Expect = e-126
 Identities = 292/607 (48%), Positives = 369/607 (60%), Gaps = 62/607 (10%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGPWS EKAEMNILEIN+K RPQLAENKQQF NLK++C +TQ+A FLANRQ  Y Y
Sbjct: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           E+CKDLIK MLR+ER   EEKLAE+L QAEELRQYKVLVHSQERELTQL+EKL+EGRDAS
Sbjct: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
           RSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRLAQHLVQKLSPEND+DEDEDV+VEE E
Sbjct: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV E  APREVQKAEE +V EDSLEECAITCSNSH PC+SNQP+ N +ITFEED+V+STL
Sbjct: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           +    SSHDE  DA+ I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 297 I--DSSSHDEWLDAVCIIP-----ENESDHEQEEEKGPVSPR----NLQESEEEEAPQES 345

Query: 301 EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
             +  +            A + +++   +  EE    +   L   R + ++   E  ++A
Sbjct: 346 WDEGDWTLSIPP---DMSASYQSDRSTFHSVEE--QQVGLALDIGRHWCDQVKKED-QEA 399

Query: 361 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD--EPDKSQGQDLQEQ 418
              R  + L+  +E E+ Q            R  +   + L  PD  +P +S    LQE 
Sbjct: 400 TSPRLSRELLDEKEPEVLQ--------DSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE- 450

Query: 419 LAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSL 475
                   QHL   L  +    D E+      E+ Q    P   RE+ +  E E  +DSL
Sbjct: 451 --------QHLGLALDLDRMKKDQEE------EEDQGPPCPRLSRELPEVVEPEDLQDSL 496

Query: 476 EECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDE 535
           +    T  +     DS QP+     + EE+ V  +L               + E E   E
Sbjct: 497 DRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSL--------------DVDEIEKYQE 542

Query: 536 EEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQ 592
            EE++ P  PR    L E+EE EV Q+S D  YST S   ++ AS++ Y S F+S EEQ 
Sbjct: 543 GEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQD 602

Query: 593 VCMAVDI 599
           V +A+D+
Sbjct: 603 VSLALDV 609



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 3/78 (3%)

Query: 169 DEDEDVQVEEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225
           D DE  + +E E+  + P PR    + +AEE +V +DSL+ C  T S       S Q ++
Sbjct: 533 DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYR 592

Query: 226 NIKITFEEDEVNSTLVVD 243
           +   +FEE +V+  L VD
Sbjct: 593 SAFYSFEEQDVSLALDVD 610


>gi|239741297 PREDICTED: neuroblastoma breakpoint family, member 9
           [Homo sapiens]
          Length = 299

 Score =  525 bits (1353), Expect = e-149
 Identities = 268/287 (93%), Positives = 275/287 (95%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKY 331
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR+LKEKCF+TQLAGFLA QQNKYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60

Query: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 391
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 392 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAE 451
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDD+EDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
           KVQKSS+PREMQKAEEKEVPEDSLEECAIT SNSHGPYDSNQPHRKTKITFEEDKVDSTL
Sbjct: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240

Query: 512 IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 558
           IGSSSHVE EDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287



 Score =  431 bits (1107), Expect = e-120
 Identities = 225/288 (78%), Positives = 244/288 (84%), Gaps = 12/288 (4%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQF +LKE+CF+TQLAGFLA +Q KYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE  E
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +S +PRE+QKAEE +V EDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL
Sbjct: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240

Query: 241 VVDRESSHDECQDALNILP----------VPGPTSSATNVSMVVSAGP 278
           +    SSH E +DA++I+P            GP S  T+V      GP
Sbjct: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 17/112 (15%)

Query: 673 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYS 732
           D DE  + +  E+ Q  S PR   E+   +E EV +DSL     T S      D  QP+ 
Sbjct: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225

Query: 733 SAVYSLEEQYLGLALD--------------LDRIKKDQEEEEDQGPPCPRLS 770
               + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 17/104 (16%)

Query: 606 QVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQ 665
           +V ++ Q+++ PR   E+   +  EV +DSL  C  T S      DS QP+R      E+
Sbjct: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233

Query: 666 QRVGLAV--------------DMDEIEKYQEVEEDQDPSCPRLS 695
            +V   +               + E E   E EE++ P  PR S
Sbjct: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 30.8 bits (68), Expect = 6.2
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 771 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSL 822
           RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240



 Score = 30.4 bits (67), Expect = 8.1
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 3/64 (4%)

Query: 853 EEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHI 912
           E+ Q    PR    + + EE EV +DSL+ C  T S      DS Q +R    +FEE  +
Sbjct: 180 EKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236

Query: 913 SFAL 916
              L
Sbjct: 237 DSTL 240


>gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1
           [Homo sapiens]
          Length = 667

 Score =  474 bits (1219), Expect = e-133
 Identities = 279/506 (55%), Positives = 347/506 (68%), Gaps = 32/506 (6%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANQQNKYK 330
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR+LKEK  +TQ   + LANQ  KYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 390
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 391 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDV--QVE 448
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D++ED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 449 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVD 508
             EKVQ+S APRE+QK EEKEVP+DSLEECA+T SNSH P +SNQPHR TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 509 STLIGSSSHV--EREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 566
           S L+  S H   E E+A++I PEN++D EEEE K PV PRN Q  E  E+   +  +   
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSLEPGEL--TNLRDFLI 297

Query: 567 TPSIP-------PEMLASYKSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KK 609
           +P +         +   SY+    +F +L+EQ+VC A D+ R     +WD+       K+
Sbjct: 298 SPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQ 357

Query: 610 ED------QEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVL 663
            D      QE   PRLSR  L     E+ Q+SL  C  TPS   +LT S  PY S  Y  
Sbjct: 358 SDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSF 417

Query: 664 EQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPE 723
           E ++V LA+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS+   Y TPS + +
Sbjct: 418 EDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHD 476

Query: 724 LPDLGQPYSSAVYSLEEQYLGLALDL 749
           + D  QPYSS + SLE+Q    ALD+
Sbjct: 477 VSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  362 bits (930), Expect = e-100
 Identities = 235/538 (43%), Positives = 320/538 (59%), Gaps = 65/538 (12%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGF-LANRQKKYK 59
           MVVSA P SSE+AEMNILEIN++LR QLAE+ QQF +LKE+  +TQ   + LAN+ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDA 119
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVHSQ +ELTQL+EKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV--QVE 177
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPENDEDEDED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 EDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVN 237
           E EKV ESPAPREVQK EE +V +DSLEECA+TCSNSH P +SNQPH++ KITF+E EV+
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRP 297
           S LVV+ E  HDE ++ALNI     P  +  +        P+             + L P
Sbjct: 240 SALVVESEHPHDEEEEALNI-----PPENQNDHEEEEGKAPVPPRN--------RQSLEP 286

Query: 298 QLAEKKQQFRNLKEKCFLTQLAGFLAN-----QQNKYKYEECKDLIKFMLRNERQFKEEK 352
                  +  NL++   ++ +   +AN     + N Y++ E    + F+  +E       
Sbjct: 287 ------GELTNLRD-FLISPVVSHVANPGHHDKSNSYRHRE----VSFLALDE------- 328

Query: 353 LAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQG 412
             +++  A+++ +        E  L  L ++     D      +   A      P +   
Sbjct: 329 --QKVCSAQDVARDYSNPKWDETSLGFLEKQ----SDLEEVKGQETVAPRLSRGPLRVDK 382

Query: 413 QDLQEQLAEGCRLAQHLVQKLSPE-----NDNDDNEDVQVEVA---------EKVQKSSA 458
            ++ ++  +GC L   ++  L+P      +     ED QV +A         E+++  S 
Sbjct: 383 HEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEEIEDQSP 442

Query: 459 P-----REMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
           P     +E+ + +E+EVPEDS+ E  +T S  H   D +QP+  T  + E+    S L
Sbjct: 443 PCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSAL 500



 Score =  115 bits (287), Expect = 3e-25
 Identities = 109/349 (31%), Positives = 158/349 (45%), Gaps = 59/349 (16%)

Query: 605 DQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLE 664
           D+  ++ QE+  PR   E+   +  EV QDSL  C  T S     ++S QP+RS     +
Sbjct: 178 DEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234

Query: 665 QQRVGLAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 708
           +  V  A+ ++                E +   E EE + P  PR +R+ L+  E   L+
Sbjct: 235 EHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR-NRQSLEPGELTNLR 293

Query: 709 DSLGRWYSTPSGYPELPDLGQPYSSAVYS---LEEQYLGLALDLDRI------------- 752
           D L     +    P   D    Y     S   L+EQ +  A D+ R              
Sbjct: 294 DFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGF 353

Query: 753 ---KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSS 809
              + D EE + Q    PRLSR  L V + E+ Q+SLD C  TPS   +   S+ PY S+
Sbjct: 354 LEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWST 413

Query: 810 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLME 869
            Y+ E+K V  +L V +I+K                    +E  EDQ+PPCPRL+  L E
Sbjct: 414 LYSFEDKQVSLAL-VDKIKKD-------------------QEEIEDQSPPCPRLSQELPE 453

Query: 870 VEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYV 918
           V+E EV +DS++  Y TPS++ ++ D  Q Y S   S E+Q    AL V
Sbjct: 454 VKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 55/247 (22%), Positives = 104/247 (42%), Gaps = 49/247 (19%)

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDV------QVEEDEKV 182
           P +    ++ ++  +GC L   ++  L+P            ED+ V      ++++D++ 
Sbjct: 377 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 436

Query: 183 LESPAP------REVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEV 236
           +E  +P      +E+ + +E +V EDS+ E  +T S  H   D +QP+            
Sbjct: 437 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPY------------ 484

Query: 237 NSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE------ 290
           +STL      S  E Q A + L V  PT +A        +G LS  ++E+ I +      
Sbjct: 485 SSTL------SSLEDQLACSALDVASPTEAA--CPQGTWSGDLSHHRSEVQISQAQLEPS 536

Query: 291 --INEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQ--NKYKYEECKDLIKFMLRNER 346
             +   LR QL +       L ++   +    F AN    N++ ++E        ++N  
Sbjct: 537 TLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSFSANADSGNQWPFQELVLEPSLGMKNPP 596

Query: 347 QFKEEKL 353
           Q +++ L
Sbjct: 597 QLEDDAL 603



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 3/71 (4%)

Query: 850 KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909
           +E E+ Q  P PR    + + EE EV QDSL+ C  T S      +S Q +RS   +F+E
Sbjct: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 910 QHISFALYVDN 920
             +  AL V++
Sbjct: 236 HEVDSALVVES 246


>gi|114158664 hypothetical protein LOC343505 [Homo sapiens]
          Length = 421

 Score =  471 bits (1211), Expect = e-132
 Identities = 248/351 (70%), Positives = 285/351 (81%), Gaps = 10/351 (2%)

Query: 259 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL 318
           PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K  +TQ+
Sbjct: 8   PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67

Query: 319 AGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 378
           AGFLANQQNKYKYEECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL 
Sbjct: 68  AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127

Query: 379 QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438
           QLREKLREGRDAS SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND
Sbjct: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187

Query: 439 NDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKT 498
            D++E+ + +  +KVQ+S APRE QKAEEKEVPEDSLEECAITYSNSHGP DSN PH+  
Sbjct: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247

Query: 499 KITFEEDKVDSTLI--GSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR--------NL 548
           KIT EEDKV+S L+    SS  E +DA++I+ EN++DDEEEE K PV P+         L
Sbjct: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307

Query: 549 QESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDI 599
           QESEE+EV Q+S +E  +T     ++  SY+    TF +L EQ+VC A D+
Sbjct: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358



 Score =  415 bits (1067), Expect = e-116
 Identities = 212/258 (82%), Positives = 229/258 (88%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60
           MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQF N+K++  +TQ+AGFLAN+Q KYKY
Sbjct: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120
           EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL QL+EKLREGRDAS
Sbjct: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180
            SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND DEDE+ + +E +
Sbjct: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200

Query: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV ESPAPRE QKAEE +V EDSLEECAIT SNSHGP DSN PHKNIKIT EED+VNS L
Sbjct: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260

Query: 241 VVDRESSHDECQDALNIL 258
           VVD ESS DE QDALNIL
Sbjct: 261 VVDSESSQDEWQDALNIL 278



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 56/209 (26%), Positives = 91/209 (43%), Gaps = 27/209 (12%)

Query: 648 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 707
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 708 QDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLD----------------R 751
           +DSL     T S      D   P+ +   + EE  +   L +D                 
Sbjct: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 752 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPY 806
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S+QP 
Sbjct: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 807 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 835
             +F AL E+ V  + DV       KG++
Sbjct: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 49/173 (28%), Positives = 75/173 (43%), Gaps = 11/173 (6%)

Query: 748 DLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYG 807
           D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245

Query: 808 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLN--- 864
           +     EE  V   L V   + +    + +   +     +   E EE + P  P++    
Sbjct: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302

Query: 865 -GV-LMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA 915
            G+ L E EE EVLQDS +   +T     ++  S+Q     F +  EQ +  A
Sbjct: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355


>gi|221218991 neuroblastoma breakpoint family, member 4 [Homo
           sapiens]
          Length = 638

 Score =  470 bits (1209), Expect = e-132
 Identities = 289/547 (52%), Positives = 355/547 (64%), Gaps = 54/547 (9%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANQQNKYK 330
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR+LKEK  +TQ   + LANQ  KYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 390
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 391 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDV--QVE 448
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D++ED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 449 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVD 508
             EKVQ+S APRE+QK EEKEVP+DSLEECA+T SNSH P +SNQPHR TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 509 STLIGSSSHV--EREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 566
           S L+  S H   E E+A++I PEN++D EEEE K PV PR+  +S               
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285

Query: 567 TPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 611
                     SY+    +F +L+EQ+VC A D+ R     +WD+       K+ D     
Sbjct: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 612 -QEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGL 670
            QE   PRLSR  L     E+ Q+SL  C  TPS   +LT S  PY S  Y  E ++V L
Sbjct: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395

Query: 671 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQP 730
           A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS+   Y TPS + ++ D  QP
Sbjct: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454

Query: 731 YSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 790
           YSS + SLE+Q    ALD   +    E    QG     LS    EV   +V Q  L+   
Sbjct: 455 YSSTLSSLEDQLACSALD---VASPTEAACPQGTWSGDLSHHQSEV---QVSQAQLEPST 508

Query: 791 STPSSCL 797
             P SCL
Sbjct: 509 LVP-SCL 514



 Score =  358 bits (920), Expect = 1e-98
 Identities = 240/523 (45%), Positives = 313/523 (59%), Gaps = 64/523 (12%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGF-LANRQKKYK 59
           MVVSA P SSE+AEMNILEIN++LR QLAE+ QQF +LKE+  +TQ   + LAN+ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDA 119
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVHSQ +ELTQL+EKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV--QVE 177
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPENDEDEDED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 EDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVN 237
           E EKV ESPAPREVQK EE +V +DSLEECA+TCSNSH P +SNQPH++ KITF+E EV+
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRP 297
           S LVV+ E  HDE ++ALNI P                       + +    E    + P
Sbjct: 240 SALVVESEHPHDEEEEALNIPP---------------------ENQNDHEEEEGKAPVPP 278

Query: 298 QLAEKKQQFRNLKEKCFLTQ------LAGFLANQQNKYKYEECKDLIKFMLRNERQFKEE 351
           +  +K   +R+ +E  FL         A  +A   +  K++E    + F+   E+Q   E
Sbjct: 279 RHHDKSNSYRH-REVSFLALDEQKVCSAQDVARDYSNPKWDETS--LGFL---EKQSDLE 332

Query: 352 KLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQ 411
           ++  Q   A  L +  + V   E     + ++  +G   + S+   L     P       
Sbjct: 333 EVKGQETVAPRLSRGPLRVDKHE-----IPQESLDGCCLTPSILPDLTPSYHPYWSTLYS 387

Query: 412 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEEK 468
            +D Q  LA        LV K+  + D ++ ED         Q    PR   E+ + +E+
Sbjct: 388 FEDKQVSLA--------LVDKI--KKDQEEIED---------QSPPCPRLSQELPEVKEQ 428

Query: 469 EVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
           EVPEDS+ E  +T S  H   D +QP+  T  + E+    S L
Sbjct: 429 EVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSAL 471



 Score =  113 bits (282), Expect = 1e-24
 Identities = 101/327 (30%), Positives = 158/327 (48%), Gaps = 44/327 (13%)

Query: 605 DQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLE 664
           D+  ++ QE+  PR   E+   +  EV QDSL  C  T S     ++S QP+RS     +
Sbjct: 178 DEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234

Query: 665 QQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKE-----PEVLQDSLGRWYSTPS 719
           +  V  A+ ++   ++   EE++  + P  ++   +E+E     P    D    +     
Sbjct: 235 EHEVDSALVVES--EHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREV 292

Query: 720 GYPELP--------DLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSR 771
            +  L         D+ + YS+  +  +E  LG    L++ + D EE + Q    PRLSR
Sbjct: 293 SFLALDEQKVCSAQDVARDYSNPKW--DETSLGF---LEK-QSDLEEVKGQETVAPRLSR 346

Query: 772 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKG 831
             L V + E+ Q+SLD C  TPS   +   S+ PY S+ Y+ E+K V  +L V +I+K  
Sbjct: 347 GPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKKD- 404

Query: 832 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYF 891
                             +E  EDQ+PPCPRL+  L EV+E EV +DS++  Y TPS++ 
Sbjct: 405 ------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHH 446

Query: 892 ELPDSFQHYRSVFYSFEEQHISFALYV 918
           ++ D  Q Y S   S E+Q    AL V
Sbjct: 447 DVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 54/247 (21%), Positives = 104/247 (42%), Gaps = 49/247 (19%)

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDV------QVEEDEKV 182
           P +    ++ ++  +GC L   ++  L+P            ED+ V      ++++D++ 
Sbjct: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407

Query: 183 LESPAP------REVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEV 236
           +E  +P      +E+ + +E +V EDS+ E  +T S  H   D +QP+            
Sbjct: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPY------------ 455

Query: 237 NSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE------ 290
           +STL      S  E Q A + L V  PT +A        +G LS  ++E+ + +      
Sbjct: 456 SSTL------SSLEDQLACSALDVASPTEAA--CPQGTWSGDLSHHQSEVQVSQAQLEPS 507

Query: 291 --INEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQ--NKYKYEECKDLIKFMLRNER 346
             +   LR QL +       L ++   +    F AN    N++ ++E        ++N  
Sbjct: 508 TLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSFSANADSGNQWPFQELVLEPSLGMKNPP 567

Query: 347 QFKEEKL 353
           Q +++ L
Sbjct: 568 QLEDDAL 574



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 3/71 (4%)

Query: 850 KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909
           +E E+ Q  P PR    + + EE EV QDSL+ C  T S      +S Q +RS   +F+E
Sbjct: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 910 QHISFALYVDN 920
             +  AL V++
Sbjct: 236 HEVDSALVVES 246


>gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2
           [Homo sapiens]
          Length = 638

 Score =  469 bits (1208), Expect = e-132
 Identities = 275/499 (55%), Positives = 339/499 (67%), Gaps = 47/499 (9%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANQQNKYK 330
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR+LKEK  +TQ   + LANQ  KYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 390
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 391 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDV--QVE 448
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D++ED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 449 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVD 508
             EKVQ+S APRE+QK EEKEVP+DSLEECA+T SNSH P +SNQPHR TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 509 STLIGSSSHV--EREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 566
           S L+  S H   E E+A++I PEN++D EEEE K PV PR+  +S               
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285

Query: 567 TPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 611
                     SY+    +F +L+EQ+VC A D+ R     +WD+       K+ D     
Sbjct: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 612 -QEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGL 670
            QE   PRLSR  L     E+ Q+SL  C  TPS   +LT S  PY S  Y  E ++V L
Sbjct: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395

Query: 671 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQP 730
           A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS+   Y TPS + ++ D  QP
Sbjct: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454

Query: 731 YSSAVYSLEEQYLGLALDL 749
           YSS + SLE+Q    ALD+
Sbjct: 455 YSSTLSSLEDQLACSALDV 473



 Score =  358 bits (920), Expect = 1e-98
 Identities = 240/523 (45%), Positives = 313/523 (59%), Gaps = 64/523 (12%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGF-LANRQKKYK 59
           MVVSA P SSE+AEMNILEIN++LR QLAE+ QQF +LKE+  +TQ   + LAN+ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDA 119
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVHSQ +ELTQL+EKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV--QVE 177
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPENDEDEDED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 EDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVN 237
           E EKV ESPAPREVQK EE +V +DSLEECA+TCSNSH P +SNQPH++ KITF+E EV+
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRP 297
           S LVV+ E  HDE ++ALNI P                       + +    E    + P
Sbjct: 240 SALVVESEHPHDEEEEALNIPP---------------------ENQNDHEEEEGKAPVPP 278

Query: 298 QLAEKKQQFRNLKEKCFLTQ------LAGFLANQQNKYKYEECKDLIKFMLRNERQFKEE 351
           +  +K   +R+ +E  FL         A  +A   +  K++E    + F+   E+Q   E
Sbjct: 279 RHHDKSNSYRH-REVSFLALDEQKVCSAQDVARDYSNPKWDETS--LGFL---EKQSDLE 332

Query: 352 KLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQ 411
           ++  Q   A  L +  + V   E     + ++  +G   + S+   L     P       
Sbjct: 333 EVKGQETVAPRLSRGPLRVDKHE-----IPQESLDGCCLTPSILPDLTPSYHPYWSTLYS 387

Query: 412 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEEK 468
            +D Q  LA        LV K+  + D ++ ED         Q    PR   E+ + +E+
Sbjct: 388 FEDKQVSLA--------LVDKI--KKDQEEIED---------QSPPCPRLSQELPEVKEQ 428

Query: 469 EVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
           EVPEDS+ E  +T S  H   D +QP+  T  + E+    S L
Sbjct: 429 EVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSAL 471



 Score =  113 bits (282), Expect = 1e-24
 Identities = 101/327 (30%), Positives = 158/327 (48%), Gaps = 44/327 (13%)

Query: 605 DQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLE 664
           D+  ++ QE+  PR   E+   +  EV QDSL  C  T S     ++S QP+RS     +
Sbjct: 178 DEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234

Query: 665 QQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKE-----PEVLQDSLGRWYSTPS 719
           +  V  A+ ++   ++   EE++  + P  ++   +E+E     P    D    +     
Sbjct: 235 EHEVDSALVVES--EHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREV 292

Query: 720 GYPELP--------DLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSR 771
            +  L         D+ + YS+  +  +E  LG    L++ + D EE + Q    PRLSR
Sbjct: 293 SFLALDEQKVCSAQDVARDYSNPKW--DETSLGF---LEK-QSDLEEVKGQETVAPRLSR 346

Query: 772 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKG 831
             L V + E+ Q+SLD C  TPS   +   S+ PY S+ Y+ E+K V  +L V +I+K  
Sbjct: 347 GPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKKD- 404

Query: 832 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYF 891
                             +E  EDQ+PPCPRL+  L EV+E EV +DS++  Y TPS++ 
Sbjct: 405 ------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHH 446

Query: 892 ELPDSFQHYRSVFYSFEEQHISFALYV 918
           ++ D  Q Y S   S E+Q    AL V
Sbjct: 447 DVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 55/247 (22%), Positives = 104/247 (42%), Gaps = 49/247 (19%)

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDV------QVEEDEKV 182
           P +    ++ ++  +GC L   ++  L+P            ED+ V      ++++D++ 
Sbjct: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407

Query: 183 LESPAP------REVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEV 236
           +E  +P      +E+ + +E +V EDS+ E  +T S  H   D +QP+            
Sbjct: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPY------------ 455

Query: 237 NSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE------ 290
           +STL      S  E Q A + L V  PT +A        +G LS  ++E+ I +      
Sbjct: 456 SSTL------SSLEDQLACSALDVASPTEAA--CPQGTWSGDLSHHRSEVQISQAQLEPS 507

Query: 291 --INEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQ--NKYKYEECKDLIKFMLRNER 346
             +   LR QL +       L ++   +    F AN    N++ ++E        ++N  
Sbjct: 508 TLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSFSANADSGNQWPFQELVLEPSLGMKNPP 567

Query: 347 QFKEEKL 353
           Q +++ L
Sbjct: 568 QLEDDAL 574



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 3/71 (4%)

Query: 850 KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909
           +E E+ Q  P PR    + + EE EV QDSL+ C  T S      +S Q +RS   +F+E
Sbjct: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 910 QHISFALYVDN 920
             +  AL V++
Sbjct: 236 HEVDSALVVES 246


>gi|239758011 PREDICTED: hypothetical protein LOC728841, partial
           [Homo sapiens]
          Length = 166

 Score =  225 bits (573), Expect = 2e-58
 Identities = 111/144 (77%), Positives = 122/144 (84%)

Query: 797 LEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 856
           LEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 857 NPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFAL 916
           NPPCPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EEQ++  AL
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 917 YVDNRFFTLTVTSLHLVFQMEVIF 940
            VD+ + T+ V SLHLVFQ+ VIF
Sbjct: 121 DVDSEYLTMKVISLHLVFQIGVIF 144



 Score =  155 bits (393), Expect = 1e-37
 Identities = 82/123 (66%), Positives = 91/123 (73%), Gaps = 19/123 (15%)

Query: 647 LELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY-------------------QEVEEDQ 687
           LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 688 DPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLAL 747
           +P CPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 748 DLD 750
           D+D
Sbjct: 121 DVD 123



 Score =  125 bits (315), Expect = 1e-28
 Identities = 65/121 (53%), Positives = 81/121 (66%), Gaps = 19/121 (15%)

Query: 723 ELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKD-------------------QEEEEDQG 763
           E PD  QPY S+ Y+LEE+++G +LD+  I+K                    +E EEDQ 
Sbjct: 2   EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQN 61

Query: 764 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLD 823
           PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LD
Sbjct: 62  PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 121

Query: 824 V 824
           V
Sbjct: 122 V 122



 Score =  104 bits (260), Expect = 3e-22
 Identities = 60/118 (50%), Positives = 74/118 (62%), Gaps = 19/118 (16%)

Query: 577 SYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 617
           S + Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ    P
Sbjct: 6   SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCP 65

Query: 618 RLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675
           RLSRELLDEK PEVLQDSL RCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D
Sbjct: 66  RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 123



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 29/68 (42%), Positives = 41/68 (60%), Gaps = 3/68 (4%)

Query: 535 EEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQ 591
           E EE++ P  PR    L + +E EV Q+S D  YSTPS   E+    + YSS  +SLEEQ
Sbjct: 55  EGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 114

Query: 592 QVCMAVDI 599
            + +A+D+
Sbjct: 115 YLGLALDV 122



 Score = 33.5 bits (75), Expect = 0.96
 Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 3/72 (4%)

Query: 177 EEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEE 233
           +E E+    P PR   E+   +E +V +DSL+ C  T S      D  QP+ +   + EE
Sbjct: 54  KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 113

Query: 234 DEVNSTLVVDRE 245
             +   L VD E
Sbjct: 114 QYLGLALDVDSE 125


>gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  119 bits (297), Expect = 2e-26
 Identities = 76/190 (40%), Positives = 108/190 (56%), Gaps = 9/190 (4%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANQQNKYK 330
           M VSA      +AEM+ILE N+ LR +L + KQ F++L EK   ++   + L N   KYK
Sbjct: 1   MAVSATTCFGPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 390
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K++EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGV 120

Query: 391 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDN 442
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   N
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 443 EDVQVEVAEK 452
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190



 Score =  109 bits (273), Expect = 1e-23
 Identities = 70/184 (38%), Positives = 106/184 (57%), Gaps = 9/184 (4%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGF-LANRQKKYK 59
           M VSA      +AEM+ILE N+ LR +L + KQ F +L E+   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ +Q  ELT L++K++EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEN-DEDED 171
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN +  ++
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQ 175
           ED Q
Sbjct: 181 EDRQ 184


>gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  116 bits (290), Expect = 1e-25
 Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 9/190 (4%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANQQNKYK 330
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++   + L N   KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 390
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 391 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDN 442
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   N
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 443 EDVQVEVAEK 452
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190



 Score =  107 bits (266), Expect = 7e-23
 Identities = 69/184 (37%), Positives = 105/184 (57%), Gaps = 9/184 (4%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGF-LANRQKKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F +L E+   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ +Q  ELT L++K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEN-DEDED 171
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN +  ++
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQ 175
           ED Q
Sbjct: 181 EDRQ 184


>gi|239741281 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 322

 Score =  116 bits (290), Expect = 1e-25
 Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 9/190 (4%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANQQNKYK 330
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++   + L N   KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 390
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 391 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDN 442
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   N
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 443 EDVQVEVAEK 452
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190



 Score =  107 bits (266), Expect = 7e-23
 Identities = 69/184 (37%), Positives = 105/184 (57%), Gaps = 9/184 (4%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGF-LANRQKKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F +L E+   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ +Q  ELT L++K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEN-DEDED 171
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN +  ++
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQ 175
           ED Q
Sbjct: 181 EDRQ 184


>gi|239752894 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 298

 Score =  113 bits (283), Expect = 7e-25
 Identities = 75/190 (39%), Positives = 105/190 (55%), Gaps = 9/190 (4%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANQQNKYK 330
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++   + L N   KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 390
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 391 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDN 442
                +H+       + LL        Q Q   EQ+ +G +L + LV+KL  EN N   N
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKN 180

Query: 443 EDVQVEVAEK 452
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190



 Score =  104 bits (259), Expect = 4e-22
 Identities = 69/184 (37%), Positives = 103/184 (55%), Gaps = 9/184 (4%)

Query: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGF-LANRQKKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F +L E+   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ +Q  ELT L++K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEN-DEDED 171
                +H+       + LL        Q Q   EQ+ +G +L + LV+KL  EN +  ++
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKN 180

Query: 172 EDVQ 175
           ED Q
Sbjct: 181 EDRQ 184


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
            sapiens]
          Length = 2346

 Score = 83.6 bits (205), Expect = 8e-16
 Identities = 68/222 (30%), Positives = 112/222 (50%), Gaps = 20/222 (9%)

Query: 79   EEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEH-------LQALL 131
            EEKLAE+L+ A    +Y  L+  Q REL+ L++K+REGR     +  H        + LL
Sbjct: 1458 EEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLL 1517

Query: 132  TPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPREV 191
              ++ D   GQ  +EQLA+G +L + L  KLS ++ + E +   +E     L     RE+
Sbjct: 1518 RSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEP----LALRLSREL 1573

Query: 192  QKAEE-SKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDE 250
            Q+ E+  +V +  L+  ++T S+SH   DS++   +     +E E  S + +  E +H E
Sbjct: 1574 QEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHYE 1633

Query: 251  CQDALNILPVPGPTSSATNVSMVVSAGPLSSE-----KAEMN 287
             + A    P    +   ++ S V+S+ P S+      KAE N
Sbjct: 1634 EKKA---SPSHSDSIHHSSHSAVLSSKPSSTSASQGAKAESN 1672



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 70/253 (27%), Positives = 118/253 (46%), Gaps = 24/253 (9%)

Query: 350  EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEH-------LQALL 402
            EEKLAE+L+ A    +Y  L+  Q REL+ LR+K+REGR     +  H        + LL
Sbjct: 1458 EEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLL 1517

Query: 403  TPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVE-VAEKVQKSSAPRE 461
              ++ D   GQ  +EQLA+G +L + L  KLS ++   + +   +E +A ++      RE
Sbjct: 1518 RSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLS-----RE 1572

Query: 462  MQKAEEK-EVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKV--DSTLIGSSSHV 518
            +Q+ E+  EV +  L+  ++T S+SH   DS++    T    +E +   D  ++   +H 
Sbjct: 1573 LQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHY 1632

Query: 519  EREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTP---SIPPEML 575
            E + A    P +            +S +    S  +    ES     S P   + P E  
Sbjct: 1633 EEKKA---SPSHSDSIHHSSHSAVLSSKPSSTSASQGAKAESNSNPISLPTPQNTPKEAN 1689

Query: 576  ASYKSYSSTFHSL 588
             ++  +   FHS+
Sbjct: 1690 QAHSGFH--FHSI 1700



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 56/264 (21%), Positives = 107/264 (40%), Gaps = 33/264 (12%)

Query: 84   EQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTPDEPDKSQGQD 143
            E L    E  Q+       E EL +LK ++ E   +S S   +    L        +  +
Sbjct: 1005 EMLHLRAEFHQHLEEKRKAEEELKELKAQIEEAGFSSVSHIRNTMLSLC------LENAE 1058

Query: 144  LQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEE---DEKVLESPAPREVQKAEESKVT 200
            L+EQ+ E       +      E D+++ E V VE     E + ES    E +K +     
Sbjct: 1059 LKEQMGEAMSDGWEI------EEDKEKGE-VMVETVVTKEGLSESSLQAEFRKLQGKLKN 1111

Query: 201  EDSL-----EECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDAL 255
              ++     E+  ++    +       P   + +T   + +N+ LV        + +  +
Sbjct: 1112 AHNIINLLKEQLVLSSKEGNSKLT---PELLVHLTSTIERINTELVGSPGKHQHQEEGNV 1168

Query: 256  NILPVPGPTSSATNVSMVVSAGPLSSE--------KAEMNILEINEKLRPQLAEKKQQFR 307
             + P P P S     +  V A  L ++        ++  ++    + LR QL++ KQ+++
Sbjct: 1169 TVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ 1228

Query: 308  NLKEKCFLTQLAGFL-ANQQNKYK 330
            +L+EK  L++   F  AN+  KY+
Sbjct: 1229 DLQEKLLLSEATVFAQANELEKYR 1252



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 74/336 (22%), Positives = 132/336 (39%), Gaps = 49/336 (14%)

Query: 69  FMLRNERQFKEEKLAEQLKQAEE-----LRQYKVLVHSQERELTQLKEKLREGRDASRSL 123
           F L+    F EE++ ++ + + E       + KV V S +REL   K+ L +      +L
Sbjct: 20  FSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENL 79

Query: 124 NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVL 183
           N   +A             +L+ Q  E  +  +H+ + L       E++   ++E+ ++ 
Sbjct: 80  NSQNEA-------------ELRRQFEERQQETEHVYELL-------ENKIQLLQEESRLA 119

Query: 184 ESPAPREVQKAEESKVTEDSLEE--CAITCSNSHGPCDSNQPHKNIKITFEED----EVN 237
           ++ A R     E  K     L E    +T +    P D  +P +  +   + D    E+N
Sbjct: 120 KNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRIEELN 179

Query: 238 STLVVDR---ESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEK 294
            +L       E    E Q  L++L  P         SM V   P++ E  +   L  +E 
Sbjct: 180 QSLAAQERLVEQLSREKQQLLHLLEEP--------TSMEVQ--PMTEELLKQQKLNSHET 229

Query: 295 LRPQLAEKKQQFRNLKEKCFLTQLAG-FLANQQNKYKYE-ECKDLIKFMLRNERQFKEEK 352
              Q +        L+EK   T+     L  + N+  YE +C            Q  +E 
Sbjct: 230 TITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKET 289

Query: 353 LAEQLKQAEELRQYKVLVHAQERELTQLREKLREGR 388
           L  + ++ EEL Q   ++  Q   + +LRE L + +
Sbjct: 290 LKSRERETEELYQ---VIEGQNDTMAKLREMLHQSQ 322



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 78/430 (18%), Positives = 167/430 (38%), Gaps = 62/430 (14%)

Query: 64  KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQ---ERELTQLKEKLREGRDAS 120
           K  +  +L      + + + E+L + ++L  ++  +  Q   +  L +L+EK+++    +
Sbjct: 196 KQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATN 255

Query: 121 RSLNEHLQAL-----LTPDEPDKSQG--QDLQEQLAEGCRLAQHLVQKLSPENDEDEDED 173
           + L E L  +        +   K  G  Q+L+E L    R  + L Q +  +ND      
Sbjct: 256 KILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMA--- 312

Query: 174 VQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEE 233
                  K+ E     ++ +   S+ T  + ++ A+    S   C   +  K  ++  ++
Sbjct: 313 -------KLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQK 365

Query: 234 DEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINE 293
           +      + D +      + A +        S   N  +  +   L  E     +   ++
Sbjct: 366 ERQ----LADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEE-----LQNKSQ 416

Query: 294 KLRPQLAEKKQQFRNLKEKC------------FLTQLAGFLANQQNKYKYEECKDLIKFM 341
           +LR   AEK  + R  ++               L +    L  + N  K  E  +++   
Sbjct: 417 QLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEK 476

Query: 342 LRNERQFK--------EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRS 393
           LR     K        +EK +   ++ +ELRQ ++ V  ++ +L +LR+ L       +S
Sbjct: 477 LRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQS 536

Query: 394 LNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKV 453
           +   L+A          +G ++ EQL+  C+  Q L +++  +      E  Q  + +++
Sbjct: 537 MESLLRA----------KGLEV-EQLSTTCQNLQWLKEEMETKFSRWQKE--QESIIQQL 583

Query: 454 QKSSAPREMQ 463
           Q S   R  +
Sbjct: 584 QTSLHDRNKE 593



 Score = 38.9 bits (89), Expect = 0.023
 Identities = 86/424 (20%), Positives = 164/424 (38%), Gaps = 60/424 (14%)

Query: 75  RQFKEEKLAEQLKQAEELRQYKVLVHSQE-----RELTQLKEKLREGRDASRSLNEHLQA 129
           RQF+E +  ++ +   EL + K+ +  +E      E  ++   +   ++ +  L+E L+ 
Sbjct: 89  RQFEERQ--QETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKG 146

Query: 130 LLT--PDEP-DKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESP 186
           +     D P D+ +     E LA+  +  + L Q L+ +    E    + ++   +LE P
Sbjct: 147 VTKNWEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEP 206

Query: 187 APREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRES 246
              EVQ   E  + +  L        NSH    + Q   +  +   ++++  T     E+
Sbjct: 207 TSMEVQPMTEELLKQQKL--------NSHETTITQQSVSDSHLAELQEKIQQT-----EA 253

Query: 247 SHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQF 306
           ++   Q+ LN             +S  +     SS+K +  I  + E L+ +  E ++ +
Sbjct: 254 TNKILQEKLN------------EMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELY 301

Query: 307 R----------NLKEKCFLTQLAGFLANQQNKYKYEECKDL----IKFMLRNERQFKEEK 352
           +           L+E    +QL    +++      ++   L      F  + E Q  +  
Sbjct: 302 QVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRV 361

Query: 353 LAEQLKQAEELRQYKVLVHAQERELTQLREKL----REGRDASRSLNEHLQ---ALLTPD 405
           + ++ +Q  + +Q    V A   E  Q +E      +E R A + L E LQ     L   
Sbjct: 362 VRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAW 421

Query: 406 EPDKSQGQDLQEQ----LAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPRE 461
           E +K      QEQ    L       + L+Q+        DN D  +E  E + +    R 
Sbjct: 422 EAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRI 481

Query: 462 MQKA 465
             KA
Sbjct: 482 HDKA 485



 Score = 35.0 bits (79), Expect = 0.33
 Identities = 133/673 (19%), Positives = 242/673 (35%), Gaps = 161/673 (23%)

Query: 8    WSSEK------AEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYE 61
            W +EK       E NI  +N  L      +K+Q         L +    L  R    K  
Sbjct: 421  WEAEKYNEIRTQEQNIQHLNHSL-----SHKEQL--------LQEFRELLQYRDNSDKTL 467

Query: 62   ECKDLIKFMLRNERQFK--------EEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKL 113
            E  +++   LR     K        +EK +   ++ +ELRQ ++ V  ++ +L +L++ L
Sbjct: 468  EANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVL 527

Query: 114  REGRDASRSLN-----------------EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQ 156
                   +S+                  ++LQ L    E   S+ Q  QE + +  + + 
Sbjct: 528  SSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSL 587

Query: 157  H------------LVQKLSPENDEDEDE-------------DVQVEEDEKVLESPAPREV 191
            H            L+ KL P   E  +E             D+  + +++VLE     E+
Sbjct: 588  HDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEH--EMEI 645

Query: 192  Q--------KAEESKVTEDSLEECAITCSNSH--------GPCDSNQPHKNIKITFEEDE 235
            Q        + +ES+   + L + A+   NS         G  DS        I+ ++ E
Sbjct: 646  QGLLQSVSTREQESQAAAEKLVQ-ALMERNSELQALRQYLGGRDSLM--SQAPISNQQAE 702

Query: 236  VNSTLVVDRES--------SHDECQDALNILPVPGPTSSATNVSMVVS-AGPLSSEKAEM 286
            V  T  + +++        S D+         V  P S+  ++  V      LS+ K E+
Sbjct: 703  VTPTGCLGKQTDQGSMQIPSRDDSTSLTAKEDVSIPRSTLGDLDTVAGLEKELSNAKEEL 762

Query: 287  NILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQN-KYKYEECKDLIKFM---- 341
             ++   E+         Q    ++E+    Q A   +  +N + K +  KDL   +    
Sbjct: 763  ELMAKKERESQMELSALQSMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPE 822

Query: 342  -------LRNERQFKEEKLAEQLKQAEEL---RQYKVLVHAQERELTQLREKLREGRDAS 391
                   L  E     EK+A    Q +E+   R+ ++L+  +   L   R +L E   A 
Sbjct: 823  DIPAMERLTQEVLLLREKVASVESQGQEISGNRRQQLLLMLE--GLVDERSRLNEALQAE 880

Query: 392  RSLNEHL---QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEN----------- 437
            R L   L    A     E D++   +L+       RL + L + L   N           
Sbjct: 881  RQLYSSLVKFHAHPESSERDRTLQVELEGAQVLRSRLEEVLGRSLERLNRLETLAAIGGA 940

Query: 438  -DNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHR 496
               DD ED   E  + +++ +A    Q     ++ + +LE+   T    +  +    P  
Sbjct: 941  AAGDDTEDTSTEFTDSIEEEAAHHSHQ-----QLVKVALEKSLATVETQNPSFSPPSP-- 993

Query: 497  KTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEV 556
                          + G S+   +E+ +H+  E     EE+ +          E E +E+
Sbjct: 994  --------------MGGDSNRCLQEEMLHLRAEFHQHLEEKRK---------AEEELKEL 1030

Query: 557  PQESWDEGYSTPS 569
              +  + G+S+ S
Sbjct: 1031 KAQIEEAGFSSVS 1043



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 754  KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSWQPYGSS 809
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 810  FYALEEKHVGFSLDV 824
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 14/116 (12%)

Query: 90   EELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
            E+ R+ +  +    RE +Q  E LRE   +SRS   HLQ L    E  K + Q L E L 
Sbjct: 1909 EDNRRLQAQLSHVSREHSQETESLREALLSSRS---HLQELEKELEHQKVERQQLLEDLR 1965

Query: 150  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLE 205
            E  +   H             +E + ++E++  L+       Q+ EE +   +SL+
Sbjct: 1966 EKQQEVLHF-----------REERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQ 2010



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 14/127 (11%)

Query: 361  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 420
            E+ R+ +  +    RE +Q  E LRE   +SRS   HLQ L    E  K + Q L E L 
Sbjct: 1909 EDNRRLQAQLSHVSREHSQETESLREALLSSRS---HLQELEKELEHQKVERQQLLEDLR 1965

Query: 421  EGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
            E  +   H  ++     +ND     ++ + +           Q+ EEK+   +SL+    
Sbjct: 1966 EKQQEVLHFREERLSLQENDSRLQHKLVLLQ-----------QQCEEKQQLFESLQSELQ 2014

Query: 481  TYSNSHG 487
             Y   +G
Sbjct: 2015 IYEALYG 2021



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 41/168 (24%), Positives = 77/168 (45%), Gaps = 16/168 (9%)

Query: 18  LEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIKFM--LRNER 75
           LEI +KL+  + + ++Q  + K+     + A   + +QK+  ++  ++L K +  L+ E 
Sbjct: 353 LEI-QKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEEL 411

Query: 76  QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTPDE 135
           Q K ++L     +A E  +Y   + +QE+ +  L   L       + L E  + L   D 
Sbjct: 412 QNKSQQL-----RAWEAEKYNE-IRTQEQNIQHLNHSLSH---KEQLLQEFRELLQYRDN 462

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVL 183
            DK+   +  E L E  +L Q +  K        +++   +EE EK L
Sbjct: 463 SDKT--LEANEMLLE--KLRQRIHDKAVALERAIDEKFSALEEKEKEL 506



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 7/74 (9%)

Query: 533  DDEEEEEKGPVSP------RNLQESEEE-EVPQESWDEGYSTPSIPPEMLASYKSYSSTF 585
            D + E+++  + P      R LQE E+  EV Q   D    TPS    +  S++S SST 
Sbjct: 1552 DHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTS 1611

Query: 586  HSLEEQQVCMAVDI 599
               +E + C  +DI
Sbjct: 1612 FLSDELEACSDMDI 1625


>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
          Length = 696

 Score = 73.9 bits (180), Expect = 6e-13
 Identities = 110/529 (20%), Positives = 208/529 (39%), Gaps = 85/529 (16%)

Query: 84  EQLKQAEEL--------RQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTPDE 135
           E  KQ E+         ++Y  L   +E+EL++LKE +   R+ +R L +  Q + T   
Sbjct: 138 EHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHT--- 194

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLES----PAPREV 191
               Q QD+++Q        + LV  L            QV E +++ ++    P+ R+ 
Sbjct: 195 ----QLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPSLRKP 250

Query: 192 QKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDEC 251
             AE+  VT+ +           H P   N   +      +E   N+ +  + E+     
Sbjct: 251 DPAEQQNVTQVA-----------HSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRA 299

Query: 252 QDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKK-------- 303
           +D      +  PT                 E+ E    ++ E+ R  L E++        
Sbjct: 300 EDT----KLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAE 355

Query: 304 -----------QQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEK 352
                      +Q R  KE+    + A  L        Y   K +IKF    E Q ++++
Sbjct: 356 HLEEEHDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQR 415

Query: 353 LA-EQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQ 411
           LA +Q+++A++LR+++  +H Q  +   LR++ ++ +  +R +    QA L   E  + Q
Sbjct: 416 LAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAEL---EEGRPQ 472

Query: 412 GQDLQEQLAEGCRLAQHLVQKLSP----------ENDNDDNEDVQVEVAEKVQ-KSSAPR 460
            Q+   Q A    +   +VQ              E DN   ++ + +   + + +   PR
Sbjct: 473 HQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPR 532

Query: 461 EMQKAEEKE---------------VPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEED 505
           E     E +                 ED  EE A      + P D N+  +++    E  
Sbjct: 533 EADPESEADRAAVEDINPADDPNNQGEDEFEE-AEQVREENLP-DENEEQKQSNQKQENT 590

Query: 506 KVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE 554
           +V+  L+ + +  ++ED V    + E+++E +E+      R L+ + EE
Sbjct: 591 EVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEE 639



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 116/595 (19%), Positives = 223/595 (37%), Gaps = 117/595 (19%)

Query: 18  LEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQF 77
           L++ ++   +L++ K+   NL+E            NRQ +  +++    I   L++ +Q 
Sbjct: 158 LQLQQEKEQELSKLKETVYNLREE-----------NRQLRKAHQD----IHTQLQDVKQQ 202

Query: 78  KEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTPDEPD 137
            +  L+E  +    L  +K  + + + ++ + K+           L + L  + +  +PD
Sbjct: 203 HKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQ-----------LKDTLNRIPSLRKPD 251

Query: 138 KSQGQDLQE--QLAEGCRLAQHL----VQKLSPENDEDED-EDVQVEEDEKVLESPAPRE 190
            ++ Q++ +     +G   A+      VQ++S  ND  ++ E V    ++  L +P  +E
Sbjct: 252 PAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKE 311

Query: 191 VQ-----KAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRE 245
            +     +  + +V     EE  +   +     +            EE+   S    DRE
Sbjct: 312 AEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDRE 371

Query: 246 -SSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQ 304
                E ++A N+L             +  SA P+   ++        ++L  Q  E+ Q
Sbjct: 372 WKEQHEQREAANLL------EGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQ 425

Query: 305 QFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLI---KFMLRNERQFKEEKLAEQLK--- 358
           Q R  +E     +L G L  QQ + + +  +++    +  L   R   +E+L +Q     
Sbjct: 426 QLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQAHYDA 485

Query: 359 --------------QAEELRQYKVLVHAQERELT--QLREKLREG-------RDASRSLN 395
                         Q EE    +   H  E E       E   +G        +A R+  
Sbjct: 486 MDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAV 545

Query: 396 EHLQALLTPDE-----------------PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438
           E +     P+                  PD+++ Q    Q  E   + +HLV   +P+  
Sbjct: 546 EDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQ 605

Query: 439 NDD-NEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRK 497
            D+ +E  Q E  E+VQ      E    E+K   E + EE       ++G  D N   + 
Sbjct: 606 EDNVDEQYQEEAEEEVQ------EDLTEEKKRELEHNAEE-------TYGENDENTDDKN 652

Query: 498 TKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESE 552
                +E + D+   G   H E E            +EEEE+   V+ ++ + +E
Sbjct: 653 NDGEEQEVRDDNRPKGREEHYEEE------------EEEEEDGAAVAEKSHRRAE 695


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 167/813 (20%), Positives = 314/813 (38%), Gaps = 106/813 (13%)

Query: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEEL-RQYKVLVHSQERELTQLK-----EKLR 114
            EE +   + +LR E++ + ++   Q ++ EEL RQ +   +  E + + LK     EK  
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKEN 1233

Query: 115  EGRD----ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDE 170
              RD         NE  + L      D+   QDLQ  L E     +   ++   + D   
Sbjct: 1234 AVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHF 1293

Query: 171  DEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKIT 230
             E+ Q+E +E+  +    R+ +  EE ++  +  EE               +  +     
Sbjct: 1294 PEEEQLEREEQ--KEAKRRDRKSQEEKQLLREEREE--------------KRRRQETDRK 1337

Query: 231  FEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE 290
            F E+E    L+ +RE      Q+                   +     L  ++ E   L+
Sbjct: 1338 FREEE---QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLK 1394

Query: 291  INEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKE 350
              ++LR Q  E++QQ R  +++ F  +    L+ Q+   K+ E +  ++   R ER+F E
Sbjct: 1395 EEQQLRCQ--EREQQLRQDRDRKFREEEQQ-LSRQERDRKFREEEQQVRRQER-ERKFLE 1450

Query: 351  EKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGR-DASRSLNEHLQALLTPDEPDK 409
            E+        ++LRQ +     +E +L Q RE+ +  R +  R   E  Q L   +   K
Sbjct: 1451 EE--------QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK 1502

Query: 410  SQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKE 469
             + Q+L+ Q  E   L +               E+ Q+   E+ Q+    R+ +  EE++
Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562

Query: 470  VPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPE 529
            + ++  E+              ++  R  K   EE KV          +E E  +     
Sbjct: 1563 LRQEREEQ------------QLSRQERDRKFRLEEQKV-RRQEQERKFMEDEQQLRRQEG 1609

Query: 530  NESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGY--STPSIPPEMLASYKSYSSTFHS 587
             +   +E + K     + LQE EE+++ ++  D  +    P +  +       +      
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669

Query: 588  LEEQQVCMAVD---IGRHRWD-QVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTP 643
             EE+Q+    +   + R   D + ++E+Q+       R+ L E+  ++ +  L R +   
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE-QQLRRQELERKFREE 1728

Query: 644  SGCLELTDSCQPYRSAFY--VLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDE 701
                + T+  Q  R   Y  +LE++++       E E+ Q   +++D    R   +L  E
Sbjct: 1729 EQLRQETEQEQLRRQERYRKILEEEQL-----RPEREEQQLRRQERDRKF-REEEQLRQE 1782

Query: 702  KEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEED 761
            +E + L+                       S   +  EEQ       L + +++Q+    
Sbjct: 1783 REEQQLRSQ--------------------ESDRKFREEEQ-------LRQEREEQQLRPQ 1815

Query: 762  QGPPCPRLSRELLEVVEPEV-LQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGF 820
            Q     R   E L++ E E  L+   DR Y        Q  S +     +   E+K    
Sbjct: 1816 QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKR--- 1872

Query: 821  SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 853
                   E++ K ++   RR +KE +R R+ GE
Sbjct: 1873 -----RQERERKLREEHIRRQQKEEQRHRQVGE 1900



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 140/715 (19%), Positives = 278/715 (38%), Gaps = 75/715 (10%)

Query: 54   RQKKYKYEE-CKDLIKFMLRNERQFKEEKLAE-QLKQAEELRQYKVLVHSQERELTQLKE 111
            R+KKY+ EE  +   + +LR ER+ +  +  E Q ++ +EL+Q +  +  +ERE  +L+E
Sbjct: 986  REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045

Query: 112  KLREGRDASRSLNEHLQAL----------------------------LTPDEPDKSQGQD 143
            + R+ R+      E  Q L                            L  +EP+K + Q+
Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQE 1105

Query: 144  LQEQLAEGCRLAQHLVQKLSPENDE----------DEDEDVQVEEDEKVLESPAPREVQK 193
             + Q  E   L Q   Q L  E ++           E+E+VQ EE++ + E P  R  Q+
Sbjct: 1106 RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165

Query: 194  AEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQD 253
             E     E+ L++               +  +  +   EE+E+       R    D+  D
Sbjct: 1166 LERQYREEEELQQEEEQLLREEQEKRRQERERQYR---EEEELQRQKRKQRYRDEDQRSD 1222

Query: 254  ALNILPVPGPTSSATNVSMVVSAGPLSS-----EKAEMNILEINEKLRPQLAEKKQQFRN 308
             L     P    +A   + V   G  +      E +++   +  + L+  L E++++ R 
Sbjct: 1223 -LKWQWEP-EKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDRE 1280

Query: 309  LKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKV 368
             + + +  +   F   +Q + + ++         + E+Q   E+  E+ ++ E  R+++ 
Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340

Query: 369  LVH-AQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQ-LAEGCRL- 425
                 QERE   LR + R+ +     L    Q     +E  + + Q+ + + L E  +L 
Sbjct: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400

Query: 426  AQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNS 485
             Q   Q+L  + D    E+ Q +++ + +      E Q+   +E     LEE        
Sbjct: 1401 CQEREQQLRQDRDRKFREEEQ-QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459

Query: 486  HGPYDSNQP--HRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPV 543
            H  +   +     + +      + D   +     + R++      E E   +E E K   
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519

Query: 544  SPRNLQESE------EEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAV 597
              + L   +      +EE      + G        +    ++         EEQQ+    
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ---DRDRKFREEEQLRQEREEQQLSRQE 1576

Query: 598  DIGRHRWDQ--VKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQP 655
               + R ++  V++++QE       ++L  ++G + L+    R +      L+  +  Q 
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQL 1636

Query: 656  YRSAFYVLEQQRVGLAVD--MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 708
            +R      E+ R  L  +  +   E+ Q++  D+D    R   +LL E E + L+
Sbjct: 1637 HRQ-----ERDRKFLEEEPQLRRQEREQQLRHDRDRKF-REEEQLLQEGEEQQLR 1685



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 111/538 (20%), Positives = 214/538 (39%), Gaps = 58/538 (10%)

Query: 54   RQKKYKYEECKDLIKFMLRNERQFK---EEKLAEQLKQAEELRQYKVLVHSQERELTQLK 110
            R+++ K +E ++ ++  LR+E+Q +   EE+  + LK+ EE R        QER   +LK
Sbjct: 515  REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL------EQERREQRLK 568

Query: 111  EKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDE 170
             +  E RD      E  +      E ++   Q L+ +  E     +   Q+L  E  E+E
Sbjct: 569  REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628

Query: 171  --DEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIK 228
               + ++ EE E+  +    RE Q+  E ++  +  EE               +  + +K
Sbjct: 629  RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE---------------RLEQRLK 673

Query: 229  ITFEEDEVNSTLV-VDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMN 287
               EE+     L   ++E + +  +  +        + +    S V S       +    
Sbjct: 674  REHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQ 733

Query: 288  ILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIK----FMLR 343
              E   + R    + +++ R  +++    Q   F    Q + K E  +  +        +
Sbjct: 734  EQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793

Query: 344  NERQFKEEKLAEQ----LKQAEELRQYKVLVHAQERELTQLREKLR-EGRDASRSLNEHL 398
             ERQ + E+  ++    L + EE  Q +     +E+EL  L E+ + + R+ ++ L E  
Sbjct: 794  RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853

Query: 399  QALLTPDEPDKSQGQDLQE----QLAEGCRLAQH-------LVQKLSPENDNDDNEDVQV 447
              L    E  +SQ Q   +    QL E  +  +H       L ++L  E      E+ ++
Sbjct: 854  DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL 913

Query: 448  EVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKV 507
            +  E+ ++    +E Q  EE+++ ++  E+            +  + +RK K   +  + 
Sbjct: 914  QREEREKRRRQEQERQYREEEQLQQEE-EQLLREEREKRRRQERERQYRKDK---KLQQK 969

Query: 508  DSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGY 565
            +  L+G      R        E E    EEEE      + L+E  E+   QE W+  Y
Sbjct: 970  EEQLLGEEPEKRRRQ------EREKKYREEEELQQEEEQLLREEREKRRRQE-WERQY 1020



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 117/567 (20%), Positives = 224/567 (39%), Gaps = 107/567 (18%)

Query: 14   EMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLI-KFMLR 72
            E+  LE  E+L  Q  E  QQ    ++        G   +++++   E+ +D   ++ L 
Sbjct: 830  ELQFLEEEEQL--QRRERAQQLQEEED--------GLQEDQERRRSQEQRRDQKWRWQLE 879

Query: 73   NERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQ---- 128
             ER+ +   L  +    E+LR+ + L+  +E EL + + + R  ++  R   E  Q    
Sbjct: 880  EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQE 939

Query: 129  -ALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDE----------DEDEDVQVE 177
               L  +E +K + Q+ + Q  +  +L Q   Q L  E ++           E+E++Q E
Sbjct: 940  EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQE 999

Query: 178  EDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVN 237
            E++ + E    R  Q+ E     +D L++                  +  ++  EE E  
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQ------------------EEEQLLREERE-- 1039

Query: 238  STLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRP 297
               + +RE  + E ++                            ++ E  + E  E  R 
Sbjct: 1040 KRRLQERERQYREEEEL--------------------------QQEEEQLLGEERETRRR 1073

Query: 298  QLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQL 357
            Q  E ++Q+R  KE+    +    L  +  K + +E           ERQ +EE      
Sbjct: 1074 Q--ELERQYR--KEEELQQEEEQLLREEPEKRRRQE----------RERQCREE------ 1113

Query: 358  KQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQE 417
               EEL+Q +  +  +ERE  + +E  R+ R+      E  Q  L  +EP+K + Q+L+ 
Sbjct: 1114 ---EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ--LLREEPEKRRRQELER 1168

Query: 418  QLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEE 477
            Q  E   L Q   Q L  E +    E       E+  +     + QK +++   ED   +
Sbjct: 1169 QYREEEELQQEEEQLLREEQEKRRQE------RERQYREEEELQRQKRKQRYRDEDQRSD 1222

Query: 478  CAITYS-NSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEE 536
                +          N+ + K +   +  +++ + +       ++D  H++ E +  D E
Sbjct: 1223 LKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL--RDRQSQQDLQHLLGEQQERDRE 1280

Query: 537  EEEKGPVSPRNLQESEEEEVPQESWDE 563
            +E +     R+    EEE++ +E   E
Sbjct: 1281 QERR-RWQQRDRHFPEEEQLEREEQKE 1306



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 115/595 (19%), Positives = 227/595 (38%), Gaps = 81/595 (13%)

Query: 11  EKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQ-------LAGFLANRQKKYKYE-- 61
           ++ ++   E+ E  R    E +QQ    ++R F  +           L   ++K + E  
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265

Query: 62  ----ECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGR 117
               E ++  + + + ERQ    +  E+ +Q + LR+ + L   QE E  + +E+ RE +
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325

Query: 118 DASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVE 177
           +      E  +  L  ++ ++ + Q  +EQ  E         Q+L  E +E+  E     
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEE------RREQQLRREQEEERREQQLRR 379

Query: 178 EDEKVLESPAPREVQKAEESKVTEDSL----------------EECAITCSNSHGPCDSN 221
           E +   E    RE Q   E ++  +                  ++               
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHE 439

Query: 222 QPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSS 281
           Q  +  ++  E++E    L  + E+   E +     L                       
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQL-----------------KRDQEE 482

Query: 282 EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFM 341
           E+ E  +    E+ R Q   ++QQ R  +E+            ++ + K +E ++ ++  
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEE-----------RREQRLKRQEEEERLQQR 531

Query: 342 LRNERQFK--EEKLAEQL------KQAEELRQYKVLVHAQERELTQL--REKLREGRDAS 391
           LR+E+Q +  +E+  EQL      K+ E+ R+ + L   QE    QL  RE+ R  +   
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591

Query: 392 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAE 451
           R   E L+  L  +E ++ + ++ +EQ  +     +   Q+L    + ++    Q+    
Sbjct: 592 REQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL---R 648

Query: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511
           + Q+    + +++ EE+E  E  L+             +  Q   + +I     K    L
Sbjct: 649 REQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL 708

Query: 512 IGSSSHVEREDAVHIIP---ENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDE 563
              S    R+  V+  P   E +   +E+EEK       LQ  EEE   ++  +E
Sbjct: 709 --ESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 167/850 (19%), Positives = 314/850 (36%), Gaps = 105/850 (12%)

Query: 54   RQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKL 113
            RQ+  K EE ++  +  LR E+Q + E+  ++ ++ E L Q     H +ER   +L E+ 
Sbjct: 630  RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689

Query: 114  RE-GRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDE---D 169
            +E  R+  +S     Q  L  +   +      + +  EG R  Q   +K      E    
Sbjct: 690  QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ 749

Query: 170  EDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKI 229
            E+E    ++ E+        + Q  E+S+     L               + +  +  + 
Sbjct: 750  EEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQR 809

Query: 230  TFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNIL 289
               E+E        R     E +  L  L              +        ++ E  + 
Sbjct: 810  FLPEEEEKE----QRRRQRREREKELQFLEEEEQLQRRERAQQL--------QEEEDGLQ 857

Query: 290  EINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQF- 348
            E  E+ R Q   + Q++R   E+            ++ +      K  ++  LR E+Q  
Sbjct: 858  EDQERRRSQEQRRDQKWRWQLEE-----------ERKRRRHTLYAKPALQEQLRKEQQLL 906

Query: 349  --KEEKLA----EQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLN------- 395
              +EE+L     E+ ++ E+ RQY+     Q+ E   LRE+  + R   R          
Sbjct: 907  QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966

Query: 396  EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPE---------------NDND 440
            +  +  L  +EP+K + Q+ +++  E   L Q   Q L  E                D  
Sbjct: 967  QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026

Query: 441  DNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKI 500
              E+ Q+   E+ ++    RE Q  EE+E+ ++  +                Q  ++ ++
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086

Query: 501  TFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDE----EEEEKGPVSPRNLQESEEEEV 556
              EE+++           ERE       E + ++E    EE EK        Q  EEEEV
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEV 1146

Query: 557  PQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATG 616
             QE             E L   +        LE Q      +  +   +Q+ +E+QE   
Sbjct: 1147 QQEE------------EQLLREEPEKRRRQELERQY--REEEELQQEEEQLLREEQEKRR 1192

Query: 617  PRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDE 676
                R+  +E+  E+ +    + Y       +L    +P +     +   +V       E
Sbjct: 1193 QERERQYREEE--ELQRQKRKQRYRDEDQRSDLKWQWEPEKE--NAVRDNKV--YCKGRE 1246

Query: 677  IEKYQEVEEDQ--DPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSA 734
             E+++++E+ Q  D    +  + LL E++    +    RW      +PE   L +     
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306

Query: 735  VYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRE----LLEVVEPEVLQDSLDRCY 790
                + +    + +  ++ +++ EE+ +     R  RE    L E  E  + +   DR +
Sbjct: 1307 AKRRDRK----SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362

Query: 791  STPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR---- 846
                   E+    Q  G  F   E++     L   E E+K   ++++ R  ++E++    
Sbjct: 1363 R------EEELRHQEQGRKFLEEEQR-----LRRQERERKFLKEEQQLRCQEREQQLRQD 1411

Query: 847  RGRKEGEEDQ 856
            R RK  EE+Q
Sbjct: 1412 RDRKFREEEQ 1421



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 133/647 (20%), Positives = 262/647 (40%), Gaps = 78/647 (12%)

Query: 8    WSSEKAEMNILEINEKLRPQLAENKQ----QFGNLKERCFLTQLAGFLANRQKKYKYEEC 63
            W  E  + N +  N K+  +  EN+Q    +   L++R     L   L  +Q++ + +E 
Sbjct: 1225 WQWEPEKENAVRDN-KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER 1283

Query: 64   KDLIKFMLRNERQFKEEKLAEQLKQAEELR------QYKVLVHSQERELTQLKEKLREGR 117
            +       + +R F EE+  E+ +Q E  R      + K L+  +  E  + +E  R+ R
Sbjct: 1284 RR----WQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339

Query: 118  DASRSLNEHLQALLTPDEPD-KSQGQDL--QEQLAEGCRLAQHLVQKLSPENDEDEDEDV 174
            +  + L E  +  L   E D K + ++L  QEQ  +     Q L ++        E++ +
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399

Query: 175  QVEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEED 234
            + +E E+ L     R+ ++ EE +++    +                +  +  K   EE 
Sbjct: 1400 RCQEREQQLRQDRDRKFRE-EEQQLSRQERDR-----KFREEEQQVRRQERERKFLEEEQ 1453

Query: 235  EVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEK 294
            ++       R+  H + ++   +L           +           E+ ++   E + K
Sbjct: 1454 QL-------RQERHRKFREEEQLL----QEREEQQLHRQERDRKFLEEEQQLRRQERDRK 1502

Query: 295  LRPQ-----------LAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLR 343
             R Q           L E++Q  R  +++ FL Q    L  Q+   +  + +D  KF  R
Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFL-QEEQQLRRQERGQQRRQDRDR-KF--R 1558

Query: 344  NERQFKEEKLAEQLKQAE-----ELRQYKVLVHAQERELTQLREKLR--EG-----RDAS 391
             E Q ++E+  +QL + E      L + KV    QER+  +  ++LR  EG     ++  
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618

Query: 392  RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL-AQHLVQKLSPENDNDDNEDVQ-VEV 449
            R   E  Q L   +E    + +  ++ L E  +L  Q   Q+L  + D    E+ Q ++ 
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678

Query: 450  AEKVQKSSAPREMQ-KAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVD 508
             E+ Q     R+ + + EE+++     E   +         +  +  R+ +   +E + +
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738

Query: 509  STLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTP 568
                       +E    I+ E +   E EE++     R+ +  EEE++ QE  ++   + 
Sbjct: 1739 QLR-------RQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRS- 1790

Query: 569  SIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRW--DQVKKEDQE 613
                E    ++         EEQQ+      G++RW  +Q++ E+QE
Sbjct: 1791 ---QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 151/800 (18%), Positives = 300/800 (37%), Gaps = 126/800 (15%)

Query: 71   LRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLK-EKLREGRDASRSLNEHLQA 129
            LR E+Q + E   +QL++ ++LR+ + L   QE E  + K E+ R  +   R   E    
Sbjct: 401  LRREQQLRRE---QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457

Query: 130  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPR 189
            L   +E ++ + +  ++QL                + +E  +  +++EE+E+       R
Sbjct: 458  LKREEETERHEQERRKQQLKR-------------DQEEERRERWLKLEEEER-------R 497

Query: 190  EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHD 249
            E Q+  E ++  +  E                +  + +K   EE+ +   L  +++   +
Sbjct: 498  EQQERREQQLRREQEE----------------RREQRLKRQEEEERLQQRLRSEQQLRRE 541

Query: 250  ECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNL 309
            + +    +L                    L  E+ E  +    E+ R QL +++++ R  
Sbjct: 542  QEERREQLLKRE-------------EEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588

Query: 310  KEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQ------AEEL 363
            + K    +        + + K EE + L +   R +R  +EE   E+ +Q       EE 
Sbjct: 589  RLKREQEE------RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642

Query: 364  RQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGC 423
            RQ ++    QER   +L+ +  E R   R   EH +     +  ++   ++ QEQ  E  
Sbjct: 643  RQQQLRREQQERREQRLKREEEEERLEQRLKREHEE-----ERREQELAEEEQEQARE-- 695

Query: 424  RLAQHLVQ-KLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITY 482
            R+   + + +   E++ D     Q +V  + +K    R  Q+ EEK    +S  +     
Sbjct: 696  RIKSRIPKWQWQLESEADAR---QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQW---- 748

Query: 483  SNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGP 542
                   +  + HR+ +   EE + D T    +          +       ++ E +   
Sbjct: 749  ------QEEERAHRQQQ--EEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ--- 797

Query: 543  VSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRH 602
            +     Q+ E+  +P+E   E         E    +          E  Q     + G  
Sbjct: 798  LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQ 857

Query: 603  RWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYV 662
              DQ ++  QE    +  R  L+E+     +   +  Y+ P+   +L    Q  +     
Sbjct: 858  E-DQERRRSQEQRRDQKWRWQLEEE----RKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912

Query: 663  LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYP 722
            L+++        ++  +Y+E E+ Q         +LL E+  +  +    R Y       
Sbjct: 913  LQREEREKRRRQEQERQYREEEQLQQE-----EEQLLREEREKRRRQERERQYRK----- 962

Query: 723  ELPDLGQPYSSAVYSLEEQYLGLALD----LDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778
                        +   EEQ LG   +     +R KK +EEEE Q     +   +LL    
Sbjct: 963  ---------DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ-----QEEEQLLREER 1008

Query: 779  PEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGF--SLDVGEIEKKGKGKKR 836
             +  +   +R Y       ++ +           L+E+   +    ++ + E++  G++R
Sbjct: 1009 EKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEER 1068

Query: 837  RGRRSKKERRRGRKEGEEDQ 856
              RR ++  R+ RKE E  Q
Sbjct: 1069 ETRRRQELERQYRKEEELQQ 1088



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 46/165 (27%), Positives = 78/165 (47%), Gaps = 21/165 (12%)

Query: 54   RQKKYKYEEC---KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQ---ERELT 107
            R++K+  EE    +  ++   R E Q ++E   EQL++ E  R  K+L   Q   ERE  
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR--KILEEEQLRPEREEQ 1762

Query: 108  QLK--EKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPE 165
            QL+  E+ R+ R+  +   E  +  L   E D+   ++  EQL +     +   Q+L P+
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE--EQLRQ-----EREEQQLRPQ 1815

Query: 166  NDED----EDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEE 206
              +     E+E +Q+EE E+ L     R+ +  E+    E S  E
Sbjct: 1816 QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 148/760 (19%), Positives = 280/760 (36%), Gaps = 117/760 (15%)

Query: 109 LKEKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDE 168
           L +  R+  D  R      Q    P +  + + Q+ + +LAEG        ++ S + + 
Sbjct: 109 LLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEG--------EEQSEKQER 160

Query: 169 DEDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIK 228
            E  D Q  ++E   +    +E Q+ EE +  E+ L+ C    +      +  +  + ++
Sbjct: 161 LEQRDRQRRDEELWRQR---QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLE 217

Query: 229 ITF---EEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 285
           +     EE +       DR    +E ++      V                  L  E+ +
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277

Query: 286 MNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNE 345
           +  LE  E  R +  E++QQ R  +E             QQ + K EE         R E
Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRRE-------------QQLRRKQEE--------ERRE 316

Query: 346 RQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD 405
           +Q +  +  E+ +Q EE R+ ++    +ER   QLR +  E         E  +  L  +
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE---------ERREQQLRRE 367

Query: 406 EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKA 465
           + ++ + Q L+ +  +  R  Q L ++     +     + Q+   ++++     RE Q  
Sbjct: 368 QEEERREQQLRRE--QQLRREQQLRREQQLRREQQLRREQQLRREQQLR-----REQQLR 420

Query: 466 EEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVH 525
            E+++  +  EE    +   H      Q  R+ ++  E+++    L       ER +   
Sbjct: 421 REQQLRREQEEE---RHEQKH-----EQERREQRLKREQEERRDWL-KREEETERHEQER 471

Query: 526 IIPENESDDEEEEEK-----GPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKS 580
              + + D EEE  +          R  QE  E+++ +E  +          E     + 
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531

Query: 581 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCY 640
             S      EQ+          R +Q+ K ++E    +  RE   ++  E  +D L    
Sbjct: 532 LRSEQQLRREQE---------ERREQLLKREEEKRLEQERREQRLKREQEERRDQL---- 578

Query: 641 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 700
                   L    +  +      +++R+   +  +E+E+ ++ E  +     RL RE   
Sbjct: 579 --------LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQ----RLKRE--- 623

Query: 701 EKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEE 760
           E E E  Q  L           +L    Q         EE+   L     R+K++ EEE 
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE---QRLKREHEEE- 679

Query: 761 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGF 820
                  R  +EL E  + +  +    R          + D+ Q   S  Y+   K    
Sbjct: 680 -------RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ---SKVYSRPRK---- 725

Query: 821 SLDVGEIEKKGKGKKRRGRRS----KKERRRGRKEGEEDQ 856
               G+  ++ + +KRR R S    ++E R  R++ EE+Q
Sbjct: 726 --QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 113/602 (18%), Positives = 231/602 (38%), Gaps = 65/602 (10%)

Query: 264 TSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLA 323
           T     +S+ +    +++E+ +    E+ EKLR   +EK +   N+KE            
Sbjct: 165 TKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKEL----------- 213

Query: 324 NQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREK 383
               K K E  K L+  +  N  Q       E  +Q EELR+ +  +  QE ++ +  E+
Sbjct: 214 ----KRKLERAKFLLPQVQTNTLQ------EEMWRQEEELREQEKKIRKQEEKMWRQEER 263

Query: 384 LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNE 443
           LRE     R   E ++         + + ++ +++L E  +L +   Q    E    + E
Sbjct: 264 LREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323

Query: 444 DVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFE 503
           +   E  EK+ +       Q+ + +E  +   ++    +       +  +  R+ +  +E
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 383

Query: 504 EDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDE 563
           +++    +       ERE  +    E E    E+EEK      N+ E EE+E  Q+   E
Sbjct: 384 QEE---KMQEEERIREREKKMR---EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 437

Query: 564 GYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSREL 623
                    +M    +        + +Q+     +  +  W Q K  +QE        ++
Sbjct: 438 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE--KKMWRQEKMREQEDQMWEQEEKM 495

Query: 624 LDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------MDEI 677
            D++  + + D   R +       E  +  +  +  +   E+ R             D+ 
Sbjct: 496 RDQE--QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQE 553

Query: 678 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYS 737
           EK +E E  ++        E +  ++ E +Q+   +         E  +  Q     ++ 
Sbjct: 554 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 613

Query: 738 LEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 797
            EE            K  ++EEED+        +E +   + E +Q+  ++ +       
Sbjct: 614 QEE------------KMWEQEEEDK-----MQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656

Query: 798 EQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE---GEE 854
           EQ +  +         EEK  G    + E E+K +G++ +  R ++E+ RG++E   G+E
Sbjct: 657 EQEEKMREQ-------EEKMQGQEEKMREQEEKMQGQEEK-MREQEEKMRGQEEKMWGQE 708

Query: 855 DQ 856
           ++
Sbjct: 709 EK 710



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 113/567 (19%), Positives = 223/567 (39%), Gaps = 76/567 (13%)

Query: 9   SSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIK 68
           ++E+ +    E+ EKLR   +E  +   N+KE                K K E  K L+ 
Sbjct: 181 TNEELKKKNAELQEKLRLAESEKSEIQLNVKEL---------------KRKLERAKFLLP 225

Query: 69  FMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQ 128
            +  N  Q       E  +Q EELR+ +  +  QE ++ + +E+LRE     R   E ++
Sbjct: 226 QVQTNTLQ------EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMR 279

Query: 129 ALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVL---ES 185
                    + + ++ +++L E  +L +   Q    E    E E+   E++EK+    E 
Sbjct: 280 RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339

Query: 186 PAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDE--VNSTLVVD 243
              +E Q  E+ +   D  E             +  +  +  +  +E++E       + +
Sbjct: 340 LWEQEKQMREQEQKMRDQEER---MWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396

Query: 244 RESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKK 303
           RE    E ++ +                          +K E N+ E  EK       ++
Sbjct: 397 REKKMREEEETMR-------------------EQEEKMQKQEENMWEQEEK-----EWQQ 432

Query: 304 QQFRNLKEKCFLTQLAGFLANQQNKY--KYEECKDLIKFMLRNERQFKEEKLAEQ----L 357
           Q+    KEK +  +    +  Q+ K   + E+ +D  +   + ++ +++EK+ EQ     
Sbjct: 433 QRLPEQKEKLWEQEK---MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489

Query: 358 KQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQ---- 413
           +Q E++R  +  +  QE  + +  E+LRE  +  R   +  Q      E  K+Q Q    
Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549

Query: 414 -DLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPE 472
            D +E++ E  R+ +   +    E    + E+   E  EK+++       Q+ + +E  E
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609

Query: 473 DSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENES 532
              E+    +       +     ++  +  +E+K+           E+E+ +    E E 
Sbjct: 610 KMWEQEEKMWEQEE---EDKMQEQEEMMWEQEEKMQEQ---EEKMWEQEEKMR---EQEE 660

Query: 533 DDEEEEEKGPVSPRNLQESEEEEVPQE 559
              E+EEK       ++E EE+   QE
Sbjct: 661 KMREQEEKMQGQEEKMREQEEKMQGQE 687



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 46/223 (20%), Positives = 102/223 (45%), Gaps = 30/223 (13%)

Query: 8   WSSEKA---EMNILEINEKLRPQLAENKQQFGNLKERCF-----LTQLAGFLANRQKKYK 59
           W  EK    E  + E  EK+R Q    +Q+  + +ER +     L +    +  ++K ++
Sbjct: 476 WRQEKMREQEDQMWEQEEKMRDQ----EQKMWDQEERMWEQDERLREKEERMREQKKMWQ 531

Query: 60  YEECKDLIKFMLRNERQF--KEEKLAEQLKQAE---ELRQYKVLVHSQERELTQLKEKLR 114
            EE     K     E++   +EEK+ E+ +  E   ++R+ + ++  QE ++ + +EK+R
Sbjct: 532 QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591

Query: 115 EGRDASRSLNEHLQ-----------ALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLS 163
           E  +      E +Q            +   +E DK Q Q  +E + E     Q   +K+ 
Sbjct: 592 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ--EEMMWEQEEKMQEQEEKMW 649

Query: 164 PENDEDEDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEE 206
            + ++  +++ ++ E E+ ++    +  ++ E+ +  E+ + E
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE 692



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 41/210 (19%), Positives = 93/210 (44%), Gaps = 18/210 (8%)

Query: 14  EMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIKFMLRN 73
           E  + E  E +R Q  + ++Q   ++E     Q        +K  + EE     K   + 
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMRE-----QEEKMWEQEEKMQEQEE-----KMWEQE 615

Query: 74  ERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQAL--L 131
           E+ +++E+  +  +Q E + + +  +  QE ++ + +EK+RE  +  R   E +Q     
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675

Query: 132 TPDEPDKSQGQDLQEQLAEGCRLAQH-----LVQKLSPENDEDEDEDVQVEEDEKVLESP 186
             ++ +K QGQ+ + +  E     Q        +K+  + ++   ++   E++E++ +  
Sbjct: 676 MREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQK 735

Query: 187 APREVQKAE-ESKVTEDSLEECAITCSNSH 215
              + +  E E + +E  L    + C+ SH
Sbjct: 736 EKMQERLPEHEERCSEPCLPPSKVLCNMSH 765


>gi|150010604 kinesin family member 4B [Homo sapiens]
          Length = 1234

 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 126/554 (22%), Positives = 219/554 (39%), Gaps = 85/554 (15%)

Query: 11   EKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIKFM 70
            ++ E  I ++ +KL  Q    K +    +    L Q    + N++ +   +  +D  KF 
Sbjct: 603  QELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKF- 661

Query: 71   LRNERQFKEEKLAE--QLKQAEELRQYKVLVHSQ--ERELTQLKEKLREGRDASRSLNEH 126
                RQ+K++K  E  QLK+ +  RQY++L   +  +++ + L+ K  E   A++ L + 
Sbjct: 662  ----RQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDA 717

Query: 127  LQALLTPDEPDKSQGQDLQEQLAEGCR--LAQHLVQKLSPENDEDEDEDVQVEEDEKVLE 184
            LQ      +  K      +E +A   R  L   +   +S E  +    D+   ED K+L 
Sbjct: 718  LQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLL--EDRKILA 775

Query: 185  SPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQP--HKNIKITFEEDEVNSTLVV 242
                +  +K E  +     L +C  + S  HG    ++    K I+    E E+ S  + 
Sbjct: 776  QDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIA 835

Query: 243  DRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEK 302
            D +      Q  L+      P     N++                ILE    L+  + E 
Sbjct: 836  DLQ------QKLLDAESEDRPKQCWENIA---------------TILEAKCALKYLIGEL 874

Query: 303  KQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFK--EEKLAEQLKQA 360
                  +  K  +T+L   L  +Q+K     C D+ K +   +  F   E +L  +L + 
Sbjct: 875  ------VSSKIHVTKLENSL--RQSK---ASCADMQKMLFEEQNHFSEIETELQAELVRM 923

Query: 361  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 420
            E+  Q KVL    + + +Q+ EK  E + AS    + +  L   DE          E++ 
Sbjct: 924  EQQHQEKVLYLVSQLQESQMAEKQLE-KSASEKEQQLVSTLQCQDEE--------LEKMR 974

Query: 421  EGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
            E C   Q L+Q    EN+    + + ++VA +              +K +P D+L    +
Sbjct: 975  EVCEQNQQLLQ----ENEIIKQKLILLQVASR--------------QKHLPNDTL----L 1012

Query: 481  TYSNSHGPYDSNQPHRKTKITFEEDKVD-STLIGSSSHV--EREDAVHIIPENESDDEE- 536
            +  +S           + K  F E  +D   L   S H   E ED       +E DDEE 
Sbjct: 1013 SPDSSFEYIPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDEEW 1072

Query: 537  -EEEKGPVSPRNLQ 549
               +   VS +N+Q
Sbjct: 1073 KPTKLVKVSRKNIQ 1086



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 105/496 (21%), Positives = 193/496 (38%), Gaps = 106/496 (21%)

Query: 16  NILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNER 75
           +++E NEKL   L++   Q   + ER  LT+      N +   K EE +  +   L    
Sbjct: 394 SLVEENEKLSRCLSKAAGQTAQMLERIILTE----QVNEKLNAKLEELRQHVACKL---- 445

Query: 76  QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS--RSLNEHLQALLTP 133
               +KL E L+  +EL++   ++ + ++ +TQL ++      A+   ++ E  Q   +P
Sbjct: 446 --DLQKLVETLED-QELKENVEIICNLQQLITQLSDETVACTAAAIDTAVEEEAQVETSP 502

Query: 134 DEPDKSQGQDLQE------------QLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEK 181
           +    S     Q             +L     L + LV+K++  +++ +    Q +++ K
Sbjct: 503 ETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIK 562

Query: 182 VLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLV 241
            LE     EV   ++ K  E+ + E      N +    S   HK ++      E+    +
Sbjct: 563 NLE----LEVINLQKEK--EELVRELQTAKKNVNQAKLSEHRHKLLQ------ELEGQ-I 609

Query: 242 VDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAE 301
            D +   +E    L +                        E  E  + ++N+++     +
Sbjct: 610 ADLKKKLNEQSKLLKL-----------------------KESTERTVSKLNQEIWMMKNQ 646

Query: 302 KKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAE--QLKQ 359
           + Q  R +KE                        D  KF     RQ+K++K  E  QLK+
Sbjct: 647 RVQLMRQMKE------------------------DAEKF-----RQWKQKKDKEVIQLKE 677

Query: 360 AEELRQYKVLVHAQ--ERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQE 417
            +  RQY++L   +  +++ + LR K  E   A++ L + LQ      +  K      +E
Sbjct: 678 RDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKE 737

Query: 418 QLAEGCR--LAQHLVQKLSPEND----NDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVP 471
            +A   R  L   +   +S E      ND  ED ++   + VQ        +K E +E P
Sbjct: 738 GIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLK------EKKESRENP 791

Query: 472 EDSLEECAITYSNSHG 487
              L +C  + S  HG
Sbjct: 792 PPKLRKCTFSLSEVHG 807


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 167/828 (20%), Positives = 334/828 (40%), Gaps = 123/828 (14%)

Query: 18   LEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQF 77
            LE+ E  R  L E   Q   +++R  + +LA  L N ++     E K+L +  LR++ + 
Sbjct: 235  LELAEN-RKLLTEKDAQIAMMQQR--IDRLA--LLNEKQAASPLEPKELEE--LRDKNES 287

Query: 78   KEEKLAEQLKQAEELRQYKVLVHSQERELTQ----LKEKLREGRDASRSLNEHLQALLTP 133
               +L E LKQ ++L+  K  +  +  +L++    L  KLRE     + L + L  L   
Sbjct: 288  LTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEE 347

Query: 134  DEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPREVQK 193
                  +  + Q QL +    A    + L  +N+  + +  Q+EE    L+   P+E  +
Sbjct: 348  HSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGE 407

Query: 194  AEESKVTEDSLEECAITCSNSHGP-------CDSNQPHKNIKIT-----FEEDEVN-STL 240
                 +  ++L++ A T + ++          ++ +  +  K+      FEE++   S+L
Sbjct: 408  VLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSL 467

Query: 241  VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
            + D +SS      A   L      S A    +      L+SE   +N     ++   +LA
Sbjct: 468  ITDLQSSISNLSQAKEELE---QASQAHGARLTAQVASLTSELTTLN--ATIQQQDQELA 522

Query: 301  EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKE---------E 351
              KQQ +  + +   T      A+Q  +++ E+    +K   + E+Q KE         +
Sbjct: 523  GLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLK---QKEQQLKEVAEKQEATRQ 579

Query: 352  KLAEQLKQAEE------------LRQYKVLVHAQERELTQLREKLR---EGRDASRS--- 393
              A+QL  A E            L+Q + L   +  +L  L+++L+   E RD++++   
Sbjct: 580  DHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVT 639

Query: 394  --------LNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDV 445
                    L+  ++ L    E  + +  + Q Q+AE     +   QK + +      +D 
Sbjct: 640  QAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQ 699

Query: 446  QVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDS-NQPHRKTKITFEE 504
              E  + +++S    +    EEK    D+LEE     S       S  + H++ +   EE
Sbjct: 700  LQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEE 759

Query: 505  DKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQE--SWD 562
            ++      G  + +++    H   + E++    E    ++ ++  ESE E++ +E  +W 
Sbjct: 760  ERAGRK--GLEARLQQLGEAH---QAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWR 814

Query: 563  EGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRE 622
            E Y       +       Y + F   +EQ + +     +   ++ ++E QEA       E
Sbjct: 815  ERYE------DSQQEEAQYGAMF---QEQLMTL-----KEECEKARQELQEAKEKVAGIE 860

Query: 623  LLDEKGPEVLQDSLYRCYSTPSGCLELTDS----CQPYRSAFYVLEQQRVGLAVDMDEIE 678
               E      Q+ L   ++  +  L+         Q        L+++    + ++  +E
Sbjct: 861  SHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLE 920

Query: 679  KYQEVEEDQDPSCPRLSRELLDE------KEPEVLQDSLGRWYSTPSGYPELPDLGQPYS 732
                   +Q  +    SREL+ E      ++PE L++  GR + +               
Sbjct: 921  TLVRKAGEQQETA---SRELVKEPARAGDRQPEWLEEQQGRQFCST-------------Q 964

Query: 733  SAVYSLEEQYLGLALDLDRIK--------KDQEEEEDQGPPCPRLSRE 772
            +A+ ++E +   +  +L+R++        + QEE   Q     RL++E
Sbjct: 965  AALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQE 1012



 Score = 38.1 bits (87), Expect = 0.039
 Identities = 106/487 (21%), Positives = 183/487 (37%), Gaps = 103/487 (21%)

Query: 22   EKLRPQLAENKQQFGNLKERCFLTQ--LAGFLANRQKKYKYEECKDLIKFMLRNERQFKE 79
            E L+ QL E  Q+ G+ +      Q  LA F   R K   + + +D  K  +   RQ  E
Sbjct: 1165 ETLQGQLEEKAQELGHSQSALASAQRELAAF---RTKVQDHSKAEDEWKAQVARGRQEAE 1221

Query: 80   EKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTPDEPDKS 139
             K +      EE+      V  +E E  +LK  +    + S+ L E L+ L      + +
Sbjct: 1222 RKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSA 1281

Query: 140  QGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPREVQKAEESKV 199
            +  +    L E        VQ L    +E E + V  E   + L S A R  +  +E K 
Sbjct: 1282 RAAERSSALREE-------VQSL---REEAEKQRVASENLRQELTSQAERAEELGQELKA 1331

Query: 200  TEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILP 259
             ++                            F++++  STL ++                
Sbjct: 1332 WQEKF--------------------------FQKEQALSTLQLEH--------------- 1350

Query: 260  VPGPTSSATNVSMVVSAGPLSSE-KAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL 318
                TS+   VS ++ A  L  + +AE    E  ++ R +L + KQ    L+ +    Q 
Sbjct: 1351 ----TSTQALVSELLPAKHLCQQLQAEQAAAE--KRHREELEQSKQAAGGLRAELLRAQ- 1403

Query: 319  AGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 378
                          E  +LI            +K+AEQ + A++LR  K    +   +L+
Sbjct: 1404 -------------RELGELIPL---------RQKVAEQERTAQQLRAEKA---SYAEQLS 1438

Query: 379  QLREKLREGRDASRSLNE--HLQALLTPDEPDKSQGQDLQE----------QLAEGCRLA 426
             L++      + +R L E  +L       E D+++ + +QE          +LAE  R A
Sbjct: 1439 MLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREA 1498

Query: 427  QHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSH 486
            Q   ++L  E      E  +V+V E+ Q+    R+   A+ +++     E+       S 
Sbjct: 1499 QSTAREL--EVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSK 1556

Query: 487  GPYDSNQ 493
               DS+Q
Sbjct: 1557 KLADSDQ 1563



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 83/363 (22%), Positives = 150/363 (41%), Gaps = 31/363 (8%)

Query: 71   LRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ----LKEKLREGRDASRSLN-E 125
            LR E Q   E+  +Q   +E LRQ       +  EL Q     +EK  +   A  +L  E
Sbjct: 1290 LREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLE 1349

Query: 126  HL--QALLTPDEPDKSQGQDLQ-EQLAEGCRLAQHLVQ-KLSPENDEDEDEDVQVEEDEK 181
            H   QAL++   P K   Q LQ EQ A   R  + L Q K +      E    Q E  E 
Sbjct: 1350 HTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGEL 1409

Query: 182  V-LESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
            + L      + + A++ +  + S  E       +HG        +N  +    +     L
Sbjct: 1410 IPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLL----AEENRGLGERANLGRQFL 1465

Query: 241  VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
             V+ + + ++    L  +       + T ++ V      ++ + E+   +  E  + ++ 
Sbjct: 1466 EVELDQAREKYVQELAAVRA----DAETRLAEVQREAQSTARELEVMTAKY-EGAKVKVL 1520

Query: 301  EKKQQFRNLKEKCF--LTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFK--EEKLAEQ 356
            E++Q+F+  ++K    + QL  F   Q      ++ ++L K +  +++  K  ++KL   
Sbjct: 1521 EERQRFQEERQKLTAQVEQLEVFQREQT-----KQVEELSKKLADSDQASKVQQQKLKAV 1575

Query: 357  LKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQ 416
              Q  E +Q    + AQ   L +L+ +L +   A+      ++   T  +  K Q Q+LQ
Sbjct: 1576 QAQGGESQQEAQRLQAQ---LNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQ 1632

Query: 417  EQL 419
            EQL
Sbjct: 1633 EQL 1635



 Score = 34.7 bits (78), Expect = 0.43
 Identities = 124/599 (20%), Positives = 236/599 (39%), Gaps = 112/599 (18%)

Query: 54   RQKKYKYEECKDLIKFMLRNERQFKEEK---------LAEQLKQ------------AEEL 92
            RQ++++ +     ++  LR+E+Q   EK         L EQL+              EE 
Sbjct: 663  RQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEK 722

Query: 93   RQYKVLVHSQERELTQLK--------------EKLREGRDASRSLNEHLQALLTPDEPDK 138
            R+    +  Q+R +++LK              ++L E R   + L   LQ L    E  +
Sbjct: 723  RRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQL---GEAHQ 779

Query: 139  SQGQDLQEQLAEGCRLAQH--------LVQKLSPENDEDED---EDVQ----VEEDEKVL 183
            ++ + L+ +LAE    AQH        LV++++   +  ED   E+ Q     +E    L
Sbjct: 780  AETEVLRRELAE-AMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTL 838

Query: 184  E---SPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
            +     A +E+Q+A+E     +S  E  I+   +    +  + H N+    ++       
Sbjct: 839  KEECEKARQELQEAKEKVAGIESHSELQISRQQN----ELAELHANLARALQQ------- 887

Query: 241  VVDRESSHDECQDALNIL--PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKL--- 295
            V ++E    +  D L+ L   +   +     +  +V       E A   +++   +    
Sbjct: 888  VQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDR 947

Query: 296  RPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAE 355
            +P+  E++Q     ++ C  TQ A     ++ +    E + L   ++ ++ Q +EE+  +
Sbjct: 948  QPEWLEEQQG----RQFC-STQAALQAMEREAEQMGNELERLRAALMESQGQQQEER-GQ 1001

Query: 356  QLKQAEELRQYK-------VLVHAQEREL-TQLREKLREGRDASRSLNEHLQALLTPDEP 407
            Q ++   L Q +        L  A   EL  +L+  L E R    +L E L   LT  E 
Sbjct: 1002 QEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEG 1061

Query: 408  -----------DKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKS 456
                       + +Q ++L+E      +L + L +K   E ++      Q E A + + +
Sbjct: 1062 KDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKK---EKEHASGSGAQSEAAGRTEPT 1118

Query: 457  SAPREMQKAEEKEVPE---------DSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKV 507
                E  +AE  ++ +         DSLE        S    DS     + ++  +  ++
Sbjct: 1119 GPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQEL 1178

Query: 508  DSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 566
              +    +S  +RE A       +    E+E K  V+ R  QE+E +     S +E  S
Sbjct: 1179 GHSQSALAS-AQRELAAFRTKVQDHSKAEDEWKAQVA-RGRQEAERKNSLISSLEEEVS 1235


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 166/764 (21%), Positives = 303/764 (39%), Gaps = 121/764 (15%)

Query: 71   LRNERQFKEEKLAEQLKQAEELR--QYKVLVHS----------QERELTQLKEKLREGRD 118
            L+NE    E + A+ L++  EL+  Q K L  +          +E E+  L+ +++E  +
Sbjct: 1390 LKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQE-LE 1448

Query: 119  ASRSLNEHLQALLTPDEPDKSQGQDLQE---QLAEGCR-LAQHLV-------QKLSPEND 167
              R + +    LL+ D   ++Q  DLQ+   Q  E CR + +HL        QKL+ + +
Sbjct: 1449 KQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQRE 1508

Query: 168  E----DEDEDVQ----------VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSN 213
            +    ++D + Q          +E+ ++++ES    +VQ  ++  VT   LE  A+    
Sbjct: 1509 QIRELEKDRETQRNVLEHQLLELEKKDQMIESQRG-QVQDLKKQLVT---LECLALELEE 1564

Query: 214  SHGPCDSNQPH-KNIKITFEEDEVNST-LVVDRESSHDECQDALNILPVPGPTSSATNVS 271
            +H   +  Q   K ++   E   V  T L +D E    E Q   + +      S+     
Sbjct: 1565 NHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARE 1624

Query: 272  MVVSAGPLSSEKAEMNILEIN-EKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYK 330
            +      + S++ ++  L+   E L   L  + Q+    KE+    Q+      +Q K  
Sbjct: 1625 LQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERI---QVLEDQRTRQTKI- 1680

Query: 331  YEECKDLIKFMLRN-------ERQFKEEKLAE----QLKQAEELRQYKVLVHAQERELTQ 379
             EE  + IK  LR        +RQ  +E+  E       Q   L   K+++  +E+E+  
Sbjct: 1681 LEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVEC 1740

Query: 380  LREKLREGRDASRSLNEHLQAL----------LTPDEPD-KSQGQDLQEQLAEGCRLAQH 428
             +E + E ++    L + LQ L          L+  E +     Q LQE   +G    Q 
Sbjct: 1741 QQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQS 1800

Query: 429  LVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGP 488
            L  +L          D ++E  ++ Q+ +  +E +  E+ +  + +LE+  +T    HG 
Sbjct: 1801 LQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGE 1860

Query: 489  YDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKG--PVSPR 546
                Q H++     EE+         +    R  A+  +  +   +  E+EK    +  +
Sbjct: 1861 L---QDHKEQARRLEEE--------LAVEGRRVQALEEVLGDLRAESREQEKALLALQQQ 1909

Query: 547  NLQESEEEEVP----QESWDEGYSTPSIPPEMLASYKSYSSTFHSLEE----QQVCMAVD 598
              ++++E EV     Q+SW +  +      + L + ++ S +    EE    +   +   
Sbjct: 1910 CAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEA 1969

Query: 599  IGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRS 658
            +G+       KE        LSR L  E     LQ SL              D+CQ +  
Sbjct: 1970 LGKAHAALQGKEQHLLEQAELSRSL--EASTATLQASL--------------DACQAH-- 2011

Query: 659  AFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTP 718
            +  + E  R+      D+  +YQE  +    +  +   EL  ++E E L +         
Sbjct: 2012 SRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQE 2071

Query: 719  SGYPELPDLGQPYSSAVYSLEEQYLGL-----ALDLDRIKKDQE 757
            +   E  +LGQ         EE+  GL      L L   +K+QE
Sbjct: 2072 NMIQEKQNLGQERE------EEEIRGLHQSVRELQLTLAQKEQE 2109



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 121/577 (20%), Positives = 236/577 (40%), Gaps = 101/577 (17%)

Query: 22   EKLRPQLAENKQQFGNLKER-----CFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQ 76
            + L+ QL++N+++    + +       L +L   +A+ Q + +  E   L +   + ER+
Sbjct: 1288 QDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAE---LQRMEAQGERE 1344

Query: 77   FKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHL-------QA 129
              +        Q E L+   V   +Q      L+E LR  R A +  NE +       QA
Sbjct: 1345 LLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQA 1404

Query: 130  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPR 189
            L    E   +QG+ LQE LA        L Q L+   +E E    Q++E EK       R
Sbjct: 1405 LQEQGELKVAQGKALQENLA-------LLTQTLAEREEEVETLRGQIQELEK------QR 1451

Query: 190  EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHD 249
            E+QKA    ++ D  +                   +N ++  +++++            +
Sbjct: 1452 EMQKAALELLSLDLKK-------------------RNQEVDLQQEQIQEL---------E 1483

Query: 250  ECQDALNILPVPGPTSSATNVSMVVSAGPLSSEK-AEMNILEIN----EKLRPQLAEKKQ 304
            +C+  L  LP+                  L  ++  + N+LE      EK    +  ++ 
Sbjct: 1484 KCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRG 1543

Query: 305  QFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLA----EQLKQA 360
            Q ++LK++    +    L  ++N +K E  + LIK  L  +R+ +   L     +  +++
Sbjct: 1544 QVQDLKKQLVTLECLA-LELEENHHKMECQQKLIK-ELEGQRETQRVALTHLTLDLEERS 1601

Query: 361  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQAL------LTPDEPDKSQGQD 414
            +EL+     +H  E   T L  +L+E     +S  E ++ L      LT D   + Q   
Sbjct: 1602 QELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELM 1661

Query: 415  LQE---QLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREM--QKAEEKE 469
            LQ+   Q+ E  R  Q  + +       +D E +++ + E+ ++ +  R++  ++AEE +
Sbjct: 1662 LQKERIQVLEDQRTRQTKILE-------EDLEQIKLSLRERGRELTTQRQLMQERAEEGK 1714

Query: 470  VP----EDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHV------- 518
             P      SLE   +   +     +  Q H   ++   +D+++  L G    V       
Sbjct: 1715 GPSKAQRGSLEHMKLILRDKEKEVECQQEHIH-ELQELKDQLEQQLQGLHRKVGETSLLL 1773

Query: 519  -EREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE 554
             +RE  + ++   +   +E  E+G +  ++LQ   +E
Sbjct: 1774 SQREQEIVVL---QQQLQEAREQGELKEQSLQSQLDE 1807



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 184/867 (21%), Positives = 324/867 (37%), Gaps = 185/867 (21%)

Query: 10   SEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQL-----AGFL------ANRQKKY 58
            +EK  +++LE   + + +LA+  QQ   L++   + +L      G L      A R+ K 
Sbjct: 923  TEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKE 982

Query: 59   KYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ-LKEKLREGR 117
               + +D +  +        ++K+  Q KQ E+L+   V     +R + Q ++EKLRE +
Sbjct: 983  AARQHRDDLAALQEESSSLLQDKMDLQ-KQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQ 1041

Query: 118  DASR--------------SLNEHLQALLTPDEPDKSQGQDLQE-----QLAEGCRLAQHL 158
            + +R              SL E  Q LL   E D  + Q+L       Q A+G +     
Sbjct: 1042 EYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSA 1101

Query: 159  VQKLSPENDEDEDEDVQVEEDEKVLESPAPREVQK-------AEESKV---------TED 202
              +L  +  ++++ D   +E + + E  A    ++       A+E+K          TE 
Sbjct: 1102 QMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTES 1161

Query: 203  SLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRES---------------S 247
             LE  A+      G    NQ     ++      +   L    ES                
Sbjct: 1162 QLE--ALAAEQQPG----NQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWG 1215

Query: 248  HDECQDALNILPVPGPTSSATNVSMVVSA----------GPLSSEKAEMNILEINEKLRP 297
             +  Q+    L   GP  +A +   V SA             + +     + ++ E+L  
Sbjct: 1216 LEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTD 1275

Query: 298  QLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYE--------ECKDLIKFM-------- 341
              AEK Q    L++     QL+    NQ+ K K+E        E  +L + M        
Sbjct: 1276 TEAEKSQVHTELQD--LQRQLS---QNQEEKSKWEGKQNSLESELMELHETMASLQSRLR 1330

Query: 342  --------LRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRS 393
                     + ER+  +        Q E L+   V   AQ      L E LR  R A + 
Sbjct: 1331 RAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKL 1390

Query: 394  LNEHLQALLTPDEPDKSQGQDLQEQ----LAEGCRLAQHLVQKLSPENDNDDNEDVQVEV 449
             NE +       E ++ + Q LQEQ    +A+G  L ++L   L  +   +  E+V+  +
Sbjct: 1391 KNEEV-------ESERERAQALQEQGELKVAQGKALQENLA--LLTQTLAEREEEVET-L 1440

Query: 450  AEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDS 509
              ++Q+    REMQKA        +LE  ++     +   D  Q   +     E +K  S
Sbjct: 1441 RGQIQELEKQREMQKA--------ALELLSLDLKKRNQEVDLQQEQIQ-----ELEKCRS 1487

Query: 510  TLIGSSSHV-EREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTP 568
             L      V ERE  + +    + +   E EK   + RN+ E +  E+ ++         
Sbjct: 1488 VLEHLPMAVQEREQKLTV----QREQIRELEKDRETQRNVLEHQLLELEKKD-------- 1535

Query: 569  SIPPEMLASYKSYSSTFHSLEEQQVCMAVDI--GRHRWDQVKKEDQEATGPRLSREL--- 623
                +M+ S +              C+A+++    H+ +  +K  +E  G R ++ +   
Sbjct: 1536 ----QMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALT 1591

Query: 624  -----LDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIE 678
                 L+E+  E LQ    + +   S    L             L+++   +    ++IE
Sbjct: 1592 HLTLDLEERSQE-LQAQSSQIHDLESHSTVLARE----------LQERDQEVKSQREQIE 1640

Query: 679  KYQEVEEDQDPSCPRLSRELLDEKEP-EVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYS 737
            + Q  +E       R  +EL+ +KE  +VL+D   R         +   L +       S
Sbjct: 1641 ELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTR---------QTKILEEDLEQIKLS 1691

Query: 738  LEEQYLGLALDLDRIKKDQEEEEDQGP 764
            L E+  G  L   R    +  EE +GP
Sbjct: 1692 LRER--GRELTTQRQLMQERAEEGKGP 1716



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 90/419 (21%), Positives = 182/419 (43%), Gaps = 43/419 (10%)

Query: 59   KYEECKDLIKFMLRNERQFKEE---KLAEQLKQAEELRQYKVLVHSQERELTQLKEKLRE 115
            K EE    ++  LR+ ++ KEE   KL+E   Q E        +H + +   ++  +  +
Sbjct: 670  KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQ 729

Query: 116  GRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQ 175
             ++A       L+  L   E D+   QDL EQL +G   A+ L++  S    + ++  ++
Sbjct: 730  EKEALVREKAALEVRLQAVERDR---QDLAEQL-QGLSSAKELLES-SLFEAQQQNSVIE 784

Query: 176  VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDE 235
            V + +  ++     + ++  + +V    LE   +    S    + +   + +    + ++
Sbjct: 785  VTKGQLEVQIQTVTQAKEVIQGEVRCLKLE---LDTERSQAEQERDAAARQLA---QAEQ 838

Query: 236  VNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKL 295
               T +  ++++H++    +N L        + +   +  A     E  E   +E+  +L
Sbjct: 839  EGKTALEQQKAAHEK---EVNQLREKWEKERSWHQQELAKA----LESLEREKMELEMRL 891

Query: 296  RPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAE 355
            + Q  E +      +E+   TQ    L   Q + + E    L++ +L+ +++     LA+
Sbjct: 892  KEQQTEMEAIQAQREEE--RTQAESALCQMQLETEKERVS-LLETLLQTQKE-----LAD 943

Query: 356  QLKQAEELRQYKVLVHAQERELT-----QLREKLREGRDASRSLNEHLQALLTPDEPDKS 410
              +Q E LRQ   +   +E+E T     QL+E  RE ++A+R   + L AL         
Sbjct: 944  ASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003

Query: 411  QGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKE 469
               DLQ+Q+ +   L   LV +      +D    V+ EV EK++++     +QK  E+E
Sbjct: 1004 DKMDLQKQVED---LKSQLVAQ------DDSQRLVEQEVQEKLRETQEYNRIQKELERE 1053



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 116/502 (23%), Positives = 195/502 (38%), Gaps = 76/502 (15%)

Query: 9   SSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIK 68
           S  K    + +  E+LR QL   +Q+   L+      QL G  A  QK+ + EE    + 
Sbjct: 460 SLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEE----LH 515

Query: 69  FMLRNERQFKEEKLAEQLKQAEELRQYKVL---VHSQERELTQLKEKLREGRDASRSLNE 125
             +R   + +E  +  + KQ+E L +   L   + S   E   L+++  E   A     +
Sbjct: 516 LAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQ 575

Query: 126 HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLES 185
            +  L + +   K++  DL+   A   +L+  L + L+ +      + +Q+EE+ + + S
Sbjct: 576 SIAELSSSENTLKTEVADLR---AAAVKLSA-LNEALALDKVGLNQQLLQLEEENQSVCS 631

Query: 186 --PAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK-------NIKITFEEDEV 236
              A  + + A +  + E      A+   N+H      +  +       +++   EE E 
Sbjct: 632 RMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEE 691

Query: 237 NSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNI-LEINEKL 295
               + +     +     L  L              V     L  EKA + + L+  E+ 
Sbjct: 692 IQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERD 751

Query: 296 RPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKY-------------KYEECKDLI---- 338
           R  LAE+ Q   + KE   L + + F A QQN                  + K++I    
Sbjct: 752 RQDLAEQLQGLSSAKE---LLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEV 808

Query: 339 ---KFMLRNERQFKEEK---LAEQLKQAEE-----LRQYKVLVHAQERELTQLREKLREG 387
              K  L  ER   E++    A QL QAE+     L Q K    A E+E+ QLREK  + 
Sbjct: 809 RCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKA---AHEKEVNQLREKWEKE 865

Query: 388 RDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQV 447
           R      + H Q L    E  + +  +L+ +L E         Q+   E      E+   
Sbjct: 866 R------SWHQQELAKALESLEREKMELEMRLKE---------QQTEMEAIQAQREE--- 907

Query: 448 EVAEKVQKSSAPREMQKAEEKE 469
              E+ Q  SA  +MQ   EKE
Sbjct: 908 ---ERTQAESALCQMQLETEKE 926



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 94/432 (21%), Positives = 170/432 (39%), Gaps = 48/432 (11%)

Query: 71   LRNERQFKEEKLAEQLKQAEELRQYK----VLVHSQERELTQLKEKLREGRDASRSLNEH 126
            L  E + +EE LA  +++ E L + K    V + + ER+   L E+L+    A   L   
Sbjct: 713  LHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESS 772

Query: 127  L---QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVL 183
            L   Q   +  E  K Q +   + + +   + Q  V+ L  E D +  +  Q  +     
Sbjct: 773  LFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQ 832

Query: 184  ESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVD 243
             + A +E + A E +      E   +            Q       + E +++   + + 
Sbjct: 833  LAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLK 892

Query: 244  RESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKK 303
             + +  E   A             T     +    L +EK  +++LE   + + +LA+  
Sbjct: 893  EQQTEMEAIQAQR-------EEERTQAESALCQMQLETEKERVSLLETLLQTQKELADAS 945

Query: 304  QQFRNLKEKCFLTQL-----AGFLANQQNKYKYE------ECKDLIKFMLRNERQFKEEK 352
            QQ   L++   + +L      G L  Q  + + E      + +D +  +        ++K
Sbjct: 946  QQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDK 1005

Query: 353  LAEQLKQAEELRQYKVLVHAQERELTQ-LREKLREGRDASR--------------SLNEH 397
            +  Q KQ E+L+   V     +R + Q ++EKLRE ++ +R              SL E 
Sbjct: 1006 MDLQ-KQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEK 1064

Query: 398  LQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSS 457
             Q LL   E D  + Q+L   L +  + AQ   ++LS +      E ++ EV EK +   
Sbjct: 1065 EQRLLVLQEADSIRQQEL-SALRQDMQEAQGEQKELSAQ-----MELLRQEVKEK-EADF 1117

Query: 458  APREMQKAEEKE 469
              +E Q  EE E
Sbjct: 1118 LAQEAQLLEELE 1129



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 23/188 (12%)

Query: 11   EKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIKFM 70
            E  E   +E+  +L+ Q  E +      +E    TQ    L   Q + + E    L++ +
Sbjct: 878  ESLEREKMELEMRLKEQQTEMEAIQAQREEE--RTQAESALCQMQLETEKERVS-LLETL 934

Query: 71   LRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELT------------QLKEKLREGRD 118
            L+ +++     LA+  +Q E LRQ   +   +E+E T            +LKE  R+ RD
Sbjct: 935  LQTQKE-----LADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRD 989

Query: 119  ASRSLNEHLQALLTPDEPDKSQGQDLQEQLA---EGCRLAQHLVQKLSPENDEDEDEDVQ 175
               +L E   +LL      + Q +DL+ QL    +  RL +  VQ+   E  E      +
Sbjct: 990  DLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKE 1049

Query: 176  VEEDEKVL 183
            +E ++  L
Sbjct: 1050 LEREKASL 1057



 Score = 37.0 bits (84), Expect = 0.087
 Identities = 86/464 (18%), Positives = 183/464 (39%), Gaps = 56/464 (12%)

Query: 11   EKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIKFM 70
            E+A M + E + +L+    ++K+Q   L+E   +           +  + +  ++++  +
Sbjct: 1848 EQAHMTLKERHGELQ----DHKEQARRLEEELAV-----------EGRRVQALEEVLGDL 1892

Query: 71   LRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQAL 130
                R+ ++  LA Q + AE+ ++++V   + +    Q +  L+E      +L    Q+ 
Sbjct: 1893 RAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSS 1952

Query: 131  LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPRE 190
               +E  +++ + LQE L +     Q   Q L  + +     +      +  L++     
Sbjct: 1953 RHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHS 2012

Query: 191  VQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVV-DRESSHD 249
             Q  E  ++ E  +++                  ++++   +  ++   L   D E  H 
Sbjct: 2013 RQLEEALRIQEGEIQD------------------QDLRYQEDVQQLQQALAQRDEELRHQ 2054

Query: 250  ECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRP---QLAEKKQQF 306
            + ++ L    +    +     +M+     L  E+ E  I  +++ +R     LA+K+Q+ 
Sbjct: 2055 QEREQL----LEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEI 2110

Query: 307  RNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQY 366
              L+E      L     + +     E+   L     R +R+   E+L   L+Q  E R+ 
Sbjct: 2111 LELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQREL--ERLQAALRQT-EAREI 2167

Query: 367  KVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLA 426
            +    AQ+  L+     L + + +  SL E    L        S+ Q LQ++L E  R A
Sbjct: 2168 EWREKAQDLALS-----LAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDEL-ELTRRA 2221

Query: 427  QHLVQKLSP------ENDNDDNEDVQVEVAEKVQKSSAPREMQK 464
                +  SP      E  +   + VQ+     V+   +P  M+K
Sbjct: 2222 LEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEK 2265


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 127/684 (18%), Positives = 271/684 (39%), Gaps = 67/684 (9%)

Query: 103  ERELTQLKEKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKL 162
            E E  +L EK +E ++  +SL +    L T  E  + +   L+E + E        + K+
Sbjct: 1327 EMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRE-------TLAKI 1379

Query: 163  SPENDEDEDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQ 222
                 + E      E+D +  +  +  E  K ++S +    +E   ++           +
Sbjct: 1380 QESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKR-------LQE 1432

Query: 223  PHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSE 282
             H  +K   +E +    L    +S  D+ ++ +  +         T   + V+   L  +
Sbjct: 1433 SHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAK---HLETEEELKVAHCCLKEQ 1489

Query: 283  KAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFML 342
            +  +N L +N      L+EK+ +   +++     QL       QNK         I+ + 
Sbjct: 1490 EETINELRVN------LSEKETEISTIQK-----QLEAINDKLQNK---------IQEIY 1529

Query: 343  RNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALL 402
              E QF  ++++E  ++  EL+Q+K    A++  L  +  K+ E  +  +   E +Q ++
Sbjct: 1530 EKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMI 1589

Query: 403  TPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREM 462
               E  K   + LQ +  +     + +V K+  E+   + + +++    + Q+     E 
Sbjct: 1590 KEKEEMKRVQEALQIERDQLKENTKEIVAKMK-ESQEKEYQFLKMTAVNETQEKMCEIEH 1648

Query: 463  QKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVERED 522
             K E+ E  + +LE               N    ++ +T E D + S  +  +  VER+ 
Sbjct: 1649 LK-EQFETQKLNLENIETENIRLTQILHENLEEMRS-VTKERDDLRS--VEETLKVERDQ 1704

Query: 523  AVHIIPENESDDEEEEEKGPVSPRNLQESEE-------------EEVPQESWDEGYSTPS 569
                + E  + D E++E+  +   +L+E +E              E+     D  +S  +
Sbjct: 1705 LKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA 1764

Query: 570  IPPEMLASYKSYSSTFHSLEEQQ--VCMAVDIGRHRWDQVK--KEDQEATGPRLSRELLD 625
            +  + L   +        L+EQQ  +     I   + D++   ++D E +  +L  ++ +
Sbjct: 1765 LKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQE 1824

Query: 626  EKGPE----VLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDE-IEKY 680
             K  E     L+  +       S   +L    +        LE + + LA  + E +E+ 
Sbjct: 1825 LKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEM 1884

Query: 681  QEVEEDQDPSCPRLSRELLDEKE--PEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSL 738
            + V +++D +  R+   L  E++   E LQ++  R             L + +   V  L
Sbjct: 1885 KSVMKERD-NLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKL 1943

Query: 739  EEQYLGLALDLDRIKKDQEEEEDQ 762
             E+     + +  I+KD ++ +D+
Sbjct: 1944 REKISEKTIQISDIQKDLDKSKDE 1967



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 111/538 (20%), Positives = 233/538 (43%), Gaps = 73/538 (13%)

Query: 18   LEINEKLRPQLAENKQQFGNLKE-RCFLTQLAGFLANRQKKYKY--EECKDLIKFMLRNE 74
            LE  E+L+      K+Q   + E R  L++    ++  QK+ +   ++ ++ I+ +   E
Sbjct: 1473 LETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKE 1532

Query: 75   RQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTPD 134
             QF  ++++E  ++  EL+Q+K    +++  L  ++ K+ E  +  +   E +Q ++   
Sbjct: 1533 EQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEK 1592

Query: 135  EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQV----EEDEKVLESPAPRE 190
            E  K   + LQ +  +     + +V K+  E+ E E + +++    E  EK+ E    +E
Sbjct: 1593 EEMKRVQEALQIERDQLKENTKEIVAKMK-ESQEKEYQFLKMTAVNETQEKMCEIEHLKE 1651

Query: 191  VQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIK----ITFEEDEVNS---TLVVD 243
              + ++  +     E   +T             H+N++    +T E D++ S   TL V+
Sbjct: 1652 QFETQKLNLENIETENIRLT----------QILHENLEEMRSVTKERDDLRSVEETLKVE 1701

Query: 244  RESSHD----------ECQDALNIL------------PVPGPTSSATN-VSMVVSAGPLS 280
            R+   +          E Q+ L I+             + G  S  TN +S +      S
Sbjct: 1702 RDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHS 1761

Query: 281  SEKAEMNILEINEKLR-PQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECK--DL 337
            ++  +   L+I E+LR   +  K+QQ    K +  +++    L+N Q   +    K  + 
Sbjct: 1762 NDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEK 1821

Query: 338  IKFMLRNERQF--KEEKLAEQLKQAEELRQYKVLVHAQERELTQLR-------EKLREGR 388
            I+ +  NE Q    ++ + E  K+  E+ Q K  +  Q   L++L        +KL E  
Sbjct: 1822 IQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENL 1881

Query: 389  DASRSLNEHLQALLTPDEPDKSQGQDLQEQL----AEGCRLAQHL-VQKLSPENDNDDNE 443
            +  +S+ +    L   +E  K +   L+E L    A    + Q L   ++  +   +  +
Sbjct: 1882 EEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVD 1941

Query: 444  DVQVEVAEK-VQKSSAPREMQKAE---EKEVPEDSLEECAITYSNSHGPYDSNQPHRK 497
             ++ +++EK +Q S   +++ K++   +K++ E   +E  +         D N  H+K
Sbjct: 1942 KLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKE----DVNMSHKK 1995



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 145/797 (18%), Positives = 315/797 (39%), Gaps = 95/797 (11%)

Query: 18   LEINEKLRPQLAENK---QQFGNLKERCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNE 74
            ++  +K +  L EN+   Q+  NL +       +      +  YK +E ++  + +   E
Sbjct: 827  MDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREV--QE 884

Query: 75   RQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLR----------EGRDASRSLN 124
            R  + E+L EQL+  +   Q      + ERE T + EKL+          + +D  + L 
Sbjct: 885  RLNEMEQLKEQLENRDSTLQ------TVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQ 938

Query: 125  EHLQ----ALLTPDEPDKSQGQDLQEQL---AEGCRLAQHLVQKLSPENDEDEDEDVQVE 177
            E LQ     L +      +   D QEQL    E  +  Q  +  L  +  E+   ++ +E
Sbjct: 939  ESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHME 998

Query: 178  ED---------EKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC--DSNQPHKN 226
            E+         +K++     ++++      +T D  +   I           + N+  + 
Sbjct: 999  ENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQM 1058

Query: 227  IKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEM 286
            ++    E E   T + +      E Q+ L +L   G         +         ++ E+
Sbjct: 1059 LESVIAEKEQLKTDLKENIEMTIENQEELRLL---GDELKKQQEIVAQEKNHAIKKEGEL 1115

Query: 287  N-----ILEINEKLR---PQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLI 338
            +     + E+ EKL+    QL EK+QQ  N++E+             + + K  E ++L 
Sbjct: 1116 SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEM-----------SEMQKKINEIENL- 1163

Query: 339  KFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHL 398
            K  L+N+    E    E+L+ A++L +     + + + +T+ R+ L+E + +  +  +HL
Sbjct: 1164 KNELKNKELTLEHMETERLELAQKLNEN----YEEVKSITKERKVLKELQKSFETERDHL 1219

Query: 399  QALLTPDEPDKSQGQD--------LQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVA 450
            +  +   E    Q ++        L+E       L + + +K +   +  D E    ++ 
Sbjct: 1220 RGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQ 1279

Query: 451  EKVQKSSAPRE-MQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDS 509
            E++      +E +   +E    ++++ E  +    S     +       +I  E  +++ 
Sbjct: 1280 EEIPVLHEEQELLPNVKEVSETQETMNELELLTEQS----TTKDSTTLARIEMERLRLNE 1335

Query: 510  TLIGSSSHV-----EREDAVHIIPENESDDEEEEEKGPVSPRNLQESE-EEEVPQESWDE 563
                S   +     ER++   I    E   ++ +E    +   +QES+ ++E      ++
Sbjct: 1336 KFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEK 1395

Query: 564  GYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSREL 623
               T  I  EM   +K   S    +E + + ++  + +   D++K   +E    +  +E+
Sbjct: 1396 DNETTKIVSEM-EQFKPKDSALLRIEIEMLGLSKRL-QESHDEMKSVAKEKDDLQRLQEV 1453

Query: 624  LDEKGPEVLQD--SLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQ 681
            L  +  ++ ++   +   +      L++   C   +     + + RV L+    EI   Q
Sbjct: 1454 LQSESDQLKENIKEIVAKHLETEEELKVAHCC--LKEQEETINELRVNLSEKETEISTIQ 1511

Query: 682  EVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQ 741
            +  E  +       +E+  EKE +     +       +   +  +  +   SA+ S+E +
Sbjct: 1512 KQLEAINDKLQNKIQEIY-EKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESK 1570

Query: 742  YLGLALDLDRIKKDQEE 758
             L L    +R+++ QEE
Sbjct: 1571 MLELT---NRLQESQEE 1584



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 92/461 (19%), Positives = 177/461 (38%), Gaps = 78/461 (16%)

Query: 59   KYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQER-------------- 104
            K ++ K L +++   + +  +  L+  L+  E+ +Q K  +   E               
Sbjct: 587  KEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRS 646

Query: 105  ELTQLKEKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSP 164
            E  +LKEK++E     + +   +Q   +  E  K    DL+++L         L   +  
Sbjct: 647  ENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDG 706

Query: 165  ENDEDEDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPH 224
            +  +D   ++++E     L+    +EV++ E  +      EE  +       P +  +  
Sbjct: 707  KVPKDLLCNLELEGKITDLQKELNKEVEENEALR------EEVILLSELKSLPSEVERLR 760

Query: 225  KNIK--------ITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSS--ATNVSMVV 274
            K I+        IT E+D++ S  VV +ES          +L   G T    AT  S   
Sbjct: 761  KEIQDKSEELHIITSEKDKLFSE-VVHKESR------VQGLLEEIGKTKDDLATTQSNYK 813

Query: 275  SAGP---------LSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQ 325
            S            +  E+    +LE NE++  ++    ++ +            G L  +
Sbjct: 814  STDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSS------LGALKTE 867

Query: 326  QNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLR 385
             + YK +E ++  + +   ER  + E+L EQL+  +   Q        ERE T + EKL+
Sbjct: 868  LS-YKTQELQEKTREV--QERLNEMEQLKEQLENRDSTLQ------TVEREKTLITEKLQ 918

Query: 386  ----------EGRDASRSLNEHLQ----ALLTPDEPDKSQGQDLQEQL---AEGCRLAQH 428
                      + +D  + L E LQ     L +      +   D QEQL    E  +  Q 
Sbjct: 919  QTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQE 978

Query: 429  LVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKE 469
             +  L  +   + + ++ +E      K    ++M   ++K+
Sbjct: 979  TINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQ 1019


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 112/573 (19%), Positives = 229/573 (39%), Gaps = 49/573 (8%)

Query: 23   KLRPQLAENKQQFGNLK-ERCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEK 81
            +L+ +   ++++ G L+ E+C L +    +   Q + + EE   L   + ++    K ++
Sbjct: 545  ELQEKYKASQKEMGQLQMEQCELLEDQRRMQEEQGQLQ-EELHRLTLPLPKSGLLLKSQE 603

Query: 82   LAEQLKQAEELRQYKVLVHSQERELTQ-----LKEKLREGRDASRSLNEHLQALL-TPDE 135
            L  +L+   EL+     +  ++++L Q     LKE+L    +  R    H Q +L  PD+
Sbjct: 604  LLTKLEDLCELQLLYQGMQEEQKKLIQNQDCVLKEQLEIHEELRRFKESHFQEVLENPDD 663

Query: 136  P-----DKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPRE 190
                   K       + L E  +  Q +      + +  + E  ++ E+ K L++     
Sbjct: 664  SKLAKSSKCNRNKQSKLLMEQMQALQVMYDAGQAKQELLQQEQGRLLEERKRLQADLQLC 723

Query: 191  VQKAEESKVTEDSLEECAITCSNSHG---PCDSNQPHKNIKITFEEDE-----VNSTLVV 242
            +++ +  +V   S++    +   S+G   P + N   K    T +++E       ST   
Sbjct: 724  LEEMQLLQVQSPSIKMSLESYGKSYGSMVPSNENC-RKTYDTTVDDNESYYKSYTSTQTS 782

Query: 243  DRE--SSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSS-EKAEMNILEINEKLRPQL 299
             +    S+D    A         T+S ++++   S G  SS +  + + +       P  
Sbjct: 783  SKSFLKSYDSSTSASEAYGKSYCTTSNSSITYKKSYGSTSSSDTCQKSFVSSCTDEEPAE 842

Query: 300  AEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLA--EQL 357
             E  ++F  +  K  +   A     Q ++ ++ + ++ ++ +L  ++  KEE  A   + 
Sbjct: 843  PEDMERFEEMVVKVLIKLQAVQAMYQISQEEHSQLQEQMEKLLAKQKDLKEELDACEREF 902

Query: 358  KQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQE 417
            K+  E  +  +     + E+ +L+ KLRE +   ++  +    LL   E  + Q Q  QE
Sbjct: 903  KECMECLEKPMAPQNDKNEIKELQTKLRELQLQYQASMDEQGRLLVVQEQLEGQLQCCQE 962

Query: 418  QLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEE 477
            +L +       +V++   +N N +      + A  V+     +      E ++      E
Sbjct: 963  ELRQLREKRPSVVKEARGKNANKNMN----KNANGVKMKKVTKPCSDTSESDLETRKSLE 1018

Query: 478  CAITYSNSHGPYDSNQPHRKTKITFEEDK----------VDSTLIGSSSHVEREDAVHII 527
              + Y  S    D      + K   EE+K              L+   +  E   +    
Sbjct: 1019 VVLYYKASQRKLDGLAKEEEKKEEMEEEKKQVKEEAKEQCGDELVAEPADPEEAKSTEDQ 1078

Query: 528  PENESDDEEEEEKGPVSPRNLQESEEEEVPQES 560
             ENE D EEEE++        ++SEEEE   +S
Sbjct: 1079 EENEEDKEEEEKE--------EDSEEEEDDADS 1103



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 76/380 (20%), Positives = 151/380 (39%), Gaps = 42/380 (11%)

Query: 109 LKEKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDE 168
           L+E+L+E R+    LNE  +AL   +     Q  DL+ +  +         Q LS  + E
Sbjct: 222 LQEELQELRERYHFLNEEYRALQESNSSLTGQLADLESERTQRATERWLQSQTLSMTSAE 281

Query: 169 DEDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIK 228
            +  ++   E       P P      ++ +  E+ +      C       +  Q H+ + 
Sbjct: 282 SQTSEMDFLE-------PDPEMQLLRQQLRDAEEQMHGMKNKCQELCCELEELQHHRQVS 334

Query: 229 ITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNI 288
              EE++              E + A N +     + S T    + S      +K + + 
Sbjct: 335 ---EEEQ---------RRLQRELKCAQNEVLRFQTSHSVTQNEELKSRLCTLQKKYDTSQ 382

Query: 289 LEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNER-Q 347
            E NE L+ QL + + + R LK        +  + NQ  K   E    L K  L+++   
Sbjct: 383 DEQNELLKMQL-QLQTELRQLK-----VMKSTLVENQSEK---ELLCRLQKLHLQHQNVT 433

Query: 348 FKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNE------HLQAL 401
            ++EKL E+ +Q +E  Q        E EL  LR+ +   ++++    E       ++ L
Sbjct: 434 CEKEKLLERQQQLQEELQ------CHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQL 487

Query: 402 LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-NDDNEDVQVEVAEKVQKSSAPR 460
               + +  + + + +QL +   L Q  +++L   +   +D      +    + + +  +
Sbjct: 488 YQASKDELERQKHMYDQLEQDLLLCQLELKELKASHPIPEDKGKCANKCDTLLSRLTELQ 547

Query: 461 EMQKAEEKEVPEDSLEECAI 480
           E  KA +KE+ +  +E+C +
Sbjct: 548 EKYKASQKEMGQLQMEQCEL 567



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 65/294 (22%), Positives = 123/294 (41%), Gaps = 41/294 (13%)

Query: 5    AGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYK----- 59
            A P   E+ E  ++++  KL  Q  +   Q    +      Q+   LA +QK  K     
Sbjct: 841  AEPEDMERFEEMVVKVLIKL--QAVQAMYQISQEEHSQLQEQMEKLLA-KQKDLKEELDA 897

Query: 60   ----YEECKDLIKFML-----RNERQFKEEKLAE-QLK-QAEELRQYKVLVHSQE----- 103
                ++EC + ++  +     +NE +  + KL E QL+ QA    Q ++LV  ++     
Sbjct: 898  CEREFKECMECLEKPMAPQNDKNEIKELQTKLRELQLQYQASMDEQGRLLVVQEQLEGQL 957

Query: 104  ----RELTQLKEKL------REGRDASRSLNEHLQAL----LTPDEPDKSQGQDLQEQLA 149
                 EL QL+EK         G++A++++N++   +    +T    D S+  DL+ + +
Sbjct: 958  QCCQEELRQLREKRPSVVKEARGKNANKNMNKNANGVKMKKVTKPCSDTSES-DLETRKS 1016

Query: 150  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPREVQKAEESKVTEDSLEECAI 209
                L     Q+      ++E++  ++EE++K ++  A    Q  +E        EE   
Sbjct: 1017 LEVVLYYKASQRKLDGLAKEEEKKEEMEEEKKQVKEEAKE--QCGDELVAEPADPEEAKS 1074

Query: 210  TCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGP 263
            T        D  +  K      EED+ +S+L    E++     ++    P P P
Sbjct: 1075 TEDQEENEEDKEEEEKEEDSEEEEDDADSSLESPEENNPLRLSESKKSSPTPNP 1128



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 57/317 (17%), Positives = 127/317 (40%), Gaps = 19/317 (5%)

Query: 158 LVQKLSPENDEDEDEDVQVEEDEKVLE---SPAPREVQKAEESKVTEDSLEECAITCSNS 214
           L+  L  E +E+E+E+ +VEE+E+ ++   S     V K     +TE  LEE        
Sbjct: 9   LLPALYEEEEEEEEEEEEVEEEEEQVQKGGSVGSLSVNKHRGLSLTETELEELRAQVLQL 68

Query: 215 HGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVV 274
               +     + +    E+D +    +++ E      Q  +    +        ++   +
Sbjct: 69  VAELEET---RELAGQHEDDSLELQGLLEDERLASAQQAEVFTKQIQQLQGELRSLREEI 125

Query: 275 SAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYE-E 333
           S   L   + E  + EI ++L    AE  Q  R   E       +   + Q++  + + E
Sbjct: 126 S---LLEHEKESELKEIEQELHLAQAE-IQSLRQAAEDSATEHESDIASLQEDLCRMQNE 181

Query: 334 CKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRS 393
            +D+ +     E +    +   ++K +E      +       + + L+E+L+E R+    
Sbjct: 182 LEDMERIRGDYEMEIASLRAEMEMKSSEPSGSLGL------SDYSGLQEELQELRERYHF 235

Query: 394 LNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKV 453
           LNE  +AL   +     Q  DL+ +  +  R  +  +Q  +    + +++  +++  E  
Sbjct: 236 LNEEYRALQESNSSLTGQLADLESERTQ--RATERWLQSQTLSMTSAESQTSEMDFLEPD 293

Query: 454 QKSSAPREMQKAEEKEV 470
            +    R+  +  E+++
Sbjct: 294 PEMQLLRQQLRDAEEQM 310


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.129    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,391,486
Number of Sequences: 37866
Number of extensions: 2139297
Number of successful extensions: 21246
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 894
Number of HSP's that attempted gapping in prelim test: 12540
Number of HSP's gapped (non-prelim): 5955
length of query: 942
length of database: 18,247,518
effective HSP length: 112
effective length of query: 830
effective length of database: 14,006,526
effective search space: 11625416580
effective search space used: 11625416580
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.