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Search of human proteins with 83281438
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|83281438 eukaryotic translation initiation factor 3, subunit
1 alpha, 35kDa [Homo sapiens]
(258 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|83281438 eukaryotic translation initiation factor 3, subunit ... 516 e-147
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 52 5e-07
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 49 3e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 47 1e-05
gi|104526627 triadin [Homo sapiens] 47 1e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 47 2e-05
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens] 46 3e-05
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens] 46 3e-05
gi|55956788 nucleolin [Homo sapiens] 46 4e-05
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 46 4e-05
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 46 4e-05
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 46 4e-05
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 45 5e-05
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 45 5e-05
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 45 6e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 45 8e-05
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 44 1e-04
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 44 2e-04
gi|4758646 kinesin family member 3B [Homo sapiens] 44 2e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 44 2e-04
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 44 2e-04
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 44 2e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 44 2e-04
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 43 2e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 43 2e-04
gi|82830424 gon-4-like isoform a [Homo sapiens] 43 2e-04
gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sap... 43 3e-04
gi|18087817 coiled-coil domain containing 34 isoform 2 [Homo sap... 43 3e-04
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 43 3e-04
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens] 43 3e-04
>gi|83281438 eukaryotic translation initiation factor 3, subunit 1
alpha, 35kDa [Homo sapiens]
Length = 258
Score = 516 bits (1329), Expect = e-147
Identities = 258/258 (100%), Positives = 258/258 (100%)
Query: 1 MAAAAAAAGDSDSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKK 60
MAAAAAAAGDSDSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKK
Sbjct: 1 MAAAAAAAGDSDSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKK 60
Query: 61 EEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRL 120
EEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRL
Sbjct: 61 EEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRL 120
Query: 121 KKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFL 180
KKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFL
Sbjct: 121 KKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFL 180
Query: 181 EVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDL 240
EVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDL
Sbjct: 181 EVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDL 240
Query: 241 ADYGGYDGGYVQDYEDFM 258
ADYGGYDGGYVQDYEDFM
Sbjct: 241 ADYGGYDGGYVQDYEDFM 258
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 52.0 bits (123), Expect = 5e-07
Identities = 30/96 (31%), Positives = 55/96 (57%), Gaps = 2/96 (2%)
Query: 33 TAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQ 92
TA D EG+ + +D K + ++++KE+ + + + ++ K+KE+E +QK+ +
Sbjct: 303 TAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREE 362
Query: 93 EEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESD 128
EE KRLEE E + EE+L + R +K Q+E +
Sbjct: 363 EERIKRLEELEAKR--KEEERLEQEKRERKKQKEKE 396
Score = 43.5 bits (101), Expect = 2e-04
Identities = 60/249 (24%), Positives = 94/249 (37%), Gaps = 80/249 (32%)
Query: 26 RKVGGGGTAGGDRWEGEDEDED----VKDNW--------DDDDDE-------KKEEAEVK 66
+K G +W+G +EDED +K+ D+ DE +K+ + K
Sbjct: 148 KKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNK 207
Query: 67 PEVKISE-----------KKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLA 115
P I K +K ++KER++KKR EE K +L + +E + L E
Sbjct: 208 PGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEE-KAKLRKLKEKEEL--ETGKK 264
Query: 116 DKLRLKKLQEESDLELAKETFGVNNAVYGID---AMNPSSRDDFTEFGKLLKDKITQYEK 172
D+ + K+ Q + + E K V+ V A P++ +D E K KDK
Sbjct: 265 DQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDK------ 318
Query: 173 SLYYASFLEVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGL 232
+K+K EK+ K K+KKKG P
Sbjct: 319 ------------------------------------KKKKGEKEEKEKEKKKG--PSKAT 340
Query: 233 KATMKDDLA 241
M++ LA
Sbjct: 341 VKAMQEALA 349
Score = 36.6 bits (83), Expect = 0.022
Identities = 23/94 (24%), Positives = 53/94 (56%), Gaps = 3/94 (3%)
Query: 53 DDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEE 112
++++ +K+EE E ++ E K+ E+ E+E++++K+Q+E +++ +E K+LT +
Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQ 412
Query: 113 QLA---DKLRLKKLQEESDLELAKETFGVNNAVY 143
+ A + LK LQ + +K++ +Y
Sbjct: 413 REARARAEATLKLLQAQGVEVPSKDSLPKKRPIY 446
Score = 35.8 bits (81), Expect = 0.038
Identities = 51/233 (21%), Positives = 96/233 (41%), Gaps = 25/233 (10%)
Query: 12 DSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKK-EEAEVKPEVK 70
D D DA + E + G + +G+ + E K ++D+DD K+ EE ++ +
Sbjct: 15 DDIDLDALAAE--IEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGI 72
Query: 71 ISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLE 130
++++ +A K E ++ +++ KK + ++ E+L DK K + +E
Sbjct: 73 KADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVE 132
Query: 131 LAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCIS 190
+ S DD +F KL K + +KS E D S
Sbjct: 133 MY------------------SGSDDDDDFNKLPKKAKGKAQKSNKKWDGSE---EDEDNS 171
Query: 191 LEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADY 243
+I + +I NS E + + K +KK + PG +++ +DD A +
Sbjct: 172 KKIKERSRI-NSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASF 223
Score = 35.8 bits (81), Expect = 0.038
Identities = 26/101 (25%), Positives = 55/101 (54%), Gaps = 10/101 (9%)
Query: 40 EGEDEDEDVKDNWD----DDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEI 95
E ED ++ D+W+ D++ EK E +V EVK + +++ E+ +E+E ++ + +EE
Sbjct: 494 EEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEE 553
Query: 96 KKRLE----EPEEPKVLTPEE--QLADKLRLKKLQEESDLE 130
+ E + E+ KV ++ + DK K++ +S+ +
Sbjct: 554 EGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYD 594
Score = 35.8 bits (81), Expect = 0.038
Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 9/125 (7%)
Query: 12 DSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKI 71
D W+A A E KV G + E+E+E+ ++ +++D+E +EE E + E +
Sbjct: 504 DDWEAMASDEE--TEKVEGNKVHIEVKENPEEEEEEEEE--EEEDEESEEEEEEEGESEG 559
Query: 72 SEKKKIAEKIKEKERQQKKRQEEIKKRL---EEPEEPKVLTPEEQLADKLRLKKLQEESD 128
SE + EK+ +++ K ++ K + E + T EE+ DK K+ E+
Sbjct: 560 SEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDK--AKRRIEKRR 617
Query: 129 LELAK 133
LE +K
Sbjct: 618 LEHSK 622
Score = 35.4 bits (80), Expect = 0.050
Identities = 25/91 (27%), Positives = 43/91 (47%)
Query: 44 EDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPE 103
ED++ D D +KK E E K + K K K ++ + K +EE +KR EE
Sbjct: 306 EDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEER 365
Query: 104 EPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
++ E + ++ RL++ + E + KE
Sbjct: 366 IKRLEELEAKRKEEERLEQEKRERKKQKEKE 396
Score = 30.4 bits (67), Expect = 1.6
Identities = 15/52 (28%), Positives = 34/52 (65%), Gaps = 2/52 (3%)
Query: 44 EDEDVKDNWDDDDDEKKEEAEVK--PEVKISEKKKIAEKIKEKERQQKKRQE 93
E+E+ + +++ ++ EE E K E ++ ++K+ +K KEKER+++ ++E
Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKE 404
Score = 29.3 bits (64), Expect = 3.6
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 21/104 (20%)
Query: 44 EDEDVKDNWDDD------DDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQ----- 92
E+E VK D +EK E + +KKK +K K+ E+++K+++
Sbjct: 277 EEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGP 336
Query: 93 --------EEIKKRLEEPEEPKVLTPEEQL--ADKLRLKKLQEE 126
+E +L+E EE + EE++ ++L K+ +EE
Sbjct: 337 SKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEE 380
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 49.3 bits (116), Expect = 3e-06
Identities = 28/95 (29%), Positives = 56/95 (58%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRL 99
E +E+E+ + + EK++E E K + K +EK+K E+ ++K ++++K+++E ++R
Sbjct: 17 EETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEERE 76
Query: 100 EEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
EE EE + EE+ + R KK ++ E +E
Sbjct: 77 EEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111
Score = 46.2 bits (108), Expect = 3e-05
Identities = 24/74 (32%), Positives = 42/74 (56%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRL 99
E +E E+ ++ + + K++ E + E + +K K EK KEKE ++KKR+ + KK+
Sbjct: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70
Query: 100 EEPEEPKVLTPEEQ 113
EE E + EE+
Sbjct: 71 EEEEREEEEEEEEE 84
Score = 44.7 bits (104), Expect = 8e-05
Identities = 24/77 (31%), Positives = 48/77 (62%)
Query: 58 EKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADK 117
+KK+E E E + +E+++ E ++++R++K++++E KK+ +E E+ K EE+ +
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64
Query: 118 LRLKKLQEESDLELAKE 134
R KK +EE E +E
Sbjct: 65 KRKKKKEEEEREEEEEE 81
Score = 42.7 bits (99), Expect = 3e-04
Identities = 23/80 (28%), Positives = 47/80 (58%)
Query: 49 KDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVL 108
K + ++ E+ EE E + E + K+K EK KEKE+++K ++ E +K EE E+ +
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64
Query: 109 TPEEQLADKLRLKKLQEESD 128
+++ ++ R ++ +EE +
Sbjct: 65 KRKKKKEEEEREEEEEEEEE 84
Score = 42.0 bits (97), Expect = 5e-04
Identities = 26/80 (32%), Positives = 45/80 (56%), Gaps = 6/80 (7%)
Query: 55 DDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQL 114
+ +E +E E + E + K+K K K KE+++KK+ +E +KR E+ EE E++
Sbjct: 9 ETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE------EKKR 62
Query: 115 ADKLRLKKLQEESDLELAKE 134
K + KK +EE + E +E
Sbjct: 63 KRKRKKKKEEEEREEEEEEE 82
Score = 38.5 bits (88), Expect = 0.006
Identities = 25/91 (27%), Positives = 51/91 (56%), Gaps = 2/91 (2%)
Query: 38 RWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKK 97
R E E E K + + ++KEE E K + K +KK+ E+ +E+E ++++++EE K+
Sbjct: 33 RKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92
Query: 98 --RLEEPEEPKVLTPEEQLADKLRLKKLQEE 126
R + ++ + EE+ K R +K +++
Sbjct: 93 EGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 37.4 bits (85), Expect = 0.013
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 7/86 (8%)
Query: 49 KDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKER------QQKKRQEEIKKRLEEP 102
K+ + ++ E+ EE E K E K EK+K K KEK++ ++K+++EE KKR +
Sbjct: 8 KETEETEETEETEEEEEK-EGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66
Query: 103 EEPKVLTPEEQLADKLRLKKLQEESD 128
++ K E+ ++ +K +EE +
Sbjct: 67 KKKKEEEEREEEEEEEEEEKEEEEKE 92
Score = 33.1 bits (74), Expect = 0.25
Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 12/62 (19%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
+R E E+E+E E+KEE E K E + +KKK + +E+E ++KKR+ + K
Sbjct: 74 EREEEEEEEE-----------EEKEEEE-KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121
Query: 97 KR 98
K+
Sbjct: 122 KK 123
Score = 28.1 bits (61), Expect = 7.9
Identities = 14/46 (30%), Positives = 26/46 (56%)
Query: 90 KRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKET 135
K++++ KK EE EE + EE+ K + K+ ++ + E K+T
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKT 46
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 47.4 bits (111), Expect = 1e-05
Identities = 34/100 (34%), Positives = 53/100 (53%), Gaps = 5/100 (5%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVK--PEVKISEKKKIA-EKIKEKERQQKKRQEEIK 96
+ E+E ++ D KKEEA K P+ K+ EKK+ A EK KE + + KK + E K
Sbjct: 841 KAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900
Query: 97 KRLEEPEE--PKVLTPEEQLADKLRLKKLQEESDLELAKE 134
K++ PE+ P + +E K + + ++E D AKE
Sbjct: 901 KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940
Score = 38.9 bits (89), Expect = 0.004
Identities = 23/85 (27%), Positives = 45/85 (52%), Gaps = 13/85 (15%)
Query: 56 DDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR-------------LEEP 102
++EK +E +VK K +E++K K +E++ K++E KK +E+P
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885
Query: 103 EEPKVLTPEEQLADKLRLKKLQEES 127
+E KV +E+ DK ++ ++E+
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEA 910
Score = 38.1 bits (87), Expect = 0.008
Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 9/102 (8%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAE-------KIKEKERQQKKRQEE 94
E ++ V+ + + KKEEAE K +V EK+ A+ K KEK KK ++
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935
Query: 95 IK-KRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLEL-AKE 134
K K +P E K PE++ + + KK +E+ E AKE
Sbjct: 936 AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKE 977
Score = 37.4 bits (85), Expect = 0.013
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEK----IKEKERQQKKRQEEI 95
E + E+ + K + E + EVK + K EK ++A+K K KE + ++E
Sbjct: 891 EAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEA 950
Query: 96 KKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
++ +E K PEE+ + + K E D L+KE
Sbjct: 951 APEKKDTKEEKAKKPEEKPKTEAKAK----EDDKTLSKE 985
Score = 36.2 bits (82), Expect = 0.029
Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
Query: 60 KEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADK 117
KE+A+ PE +I +K+++ +KE+E+ Q+ + +E K+ EE + P EE+ K
Sbjct: 804 KEDAKA-PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK 860
Score = 35.8 bits (81), Expect = 0.038
Identities = 29/116 (25%), Positives = 51/116 (43%), Gaps = 7/116 (6%)
Query: 59 KKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEE-QLADK 117
+K ++ VK E K EK K +KE+ + +K + +K+ + PE+ K EE + +K
Sbjct: 678 EKAKSPVKAEAKSPEKAK--SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735
Query: 118 LRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKS 173
+ +E E AK +D +P ++ E + DK + KS
Sbjct: 736 AKSPVKEEAKSPEKAKSP----EKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS 787
Score = 35.8 bits (81), Expect = 0.038
Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Query: 44 EDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPE 103
E +D K EKKE A PE K ++++K A+K +EK + + K +E+ K +EP
Sbjct: 932 EPDDAKAKEPSKPAEKKEAA---PEKKDTKEEK-AKKPEEKPKTEAKAKEDDKTLSKEPS 987
Query: 104 EPKVLTPEEQLADKLRLKKLQEES 127
+PK E+ + + K E++
Sbjct: 988 KPKAEKAEKSSSTDQKDSKPPEKA 1011
Score = 32.7 bits (73), Expect = 0.32
Identities = 24/68 (35%), Positives = 38/68 (55%), Gaps = 6/68 (8%)
Query: 55 DDDEKKEEAEVKPEVKISEKKK--IAEKIKEKERQQKKRQEEIK---KRLEEPEEPKVLT 109
D +K ++ VK EVK EK K + E K E++ K+ EE+K K E+P+E KV
Sbjct: 779 DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK-EEVKSPVKEEEKPQEVKVKE 837
Query: 110 PEEQLADK 117
P ++ ++
Sbjct: 838 PPKKAEEE 845
Score = 32.3 bits (72), Expect = 0.42
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 9/93 (9%)
Query: 44 EDEDVKDNWDDDDDEK-----KEEAEVKPEVKISEKK--KIAEKIKEKERQQKKRQEEIK 96
E E+ K + EK KEEA+ PE K EK+ K ++K E+ + +EE K
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 97 KRLE--EPEEPKVLTPEEQLADKLRLKKLQEES 127
E PE+ K EE + ++EE+
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA 626
Score = 31.6 bits (70), Expect = 0.72
Identities = 16/56 (28%), Positives = 27/56 (48%)
Query: 57 DEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEE 112
+E K AE K VK K K EK + K + + ++ + PE+ + +PE+
Sbjct: 610 EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665
Score = 31.2 bits (69), Expect = 0.93
Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 59 KKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKL 118
+K ++ VK E K EK K +K + + +K + +K+ + PE+ K EE + +
Sbjct: 664 EKAKSPVKAEAKSPEKAK--SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEK 721
Query: 119 RLKKLQEES 127
++EE+
Sbjct: 722 AKSPVKEEA 730
Score = 30.4 bits (67), Expect = 1.6
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 44 EDEDVKDNWDDDDDEK-----KEEAEVKPEVKISEKKK--IAEKIKEKERQQKKRQEEIK 96
E E+ K + EK KEEA+ E K EK K + E+ K + +EE K
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAK 627
Query: 97 KRLE--EPEEPKVLTPEE-QLADKLRLKKLQEESDLELAK 133
E PE+ K T EE + +K + + +E E AK
Sbjct: 628 SPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667
Score = 30.0 bits (66), Expect = 2.1
Identities = 25/118 (21%), Positives = 44/118 (37%), Gaps = 12/118 (10%)
Query: 22 EDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDD------------DDEKKEEAEVKPEV 69
E ++ G GG+ E E +E+ K ++ +E K AE K
Sbjct: 475 EKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE 534
Query: 70 KISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEES 127
K K K EK + K + + + PE+ + +P E + + +EE+
Sbjct: 535 KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 592
Score = 30.0 bits (66), Expect = 2.1
Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 4/87 (4%)
Query: 46 EDVKDNWDDDDDEKKEEAEVK-PEVKISEKKKI---AEKIKEKERQQKKRQEEIKKRLEE 101
E+ K EK + +VK PE K K++ A+K EK + K + + ++ +
Sbjct: 742 EEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKS 801
Query: 102 PEEPKVLTPEEQLADKLRLKKLQEESD 128
P + PE+++ K +K +E +
Sbjct: 802 PLKEDAKAPEKEIPKKEEVKSPVKEEE 828
Score = 29.6 bits (65), Expect = 2.7
Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 12/100 (12%)
Query: 46 EDVKDNWDDDDDEKKEEAEVKPEVK--ISEKKKIAEKIKEKERQQKKRQE--------EI 95
E K +D ++E K EVK + E++K +++K KE +K +E E
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK-PQEVKVKEPPKKAEEEKAPATPKTEE 855
Query: 96 KKRLEEPEEPKVLTPEEQLADKLR-LKKLQEESDLELAKE 134
KK ++ E PK P+ ++ +K + +ES +E KE
Sbjct: 856 KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE 895
Score = 29.6 bits (65), Expect = 2.7
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 10/86 (11%)
Query: 53 DDDDDEKKEEAEVKPE-VKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEP-------EE 104
D EK E A+ +P+ K E K AEK + ++ ++E+ KK E+P E+
Sbjct: 919 DAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKED 978
Query: 105 PKVLT--PEEQLADKLRLKKLQEESD 128
K L+ P + A+K ++ D
Sbjct: 979 DKTLSKEPSKPKAEKAEKSSSTDQKD 1004
Score = 29.3 bits (64), Expect = 3.6
Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 4/57 (7%)
Query: 60 KEEAEVKPEVKISEKKK--IAEKIKEKERQQKKRQEEIK--KRLEEPEEPKVLTPEE 112
KEEA+ EVK EK K E+ K E+ + +EE K ++ + P + + +PE+
Sbjct: 623 KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK 679
Score = 29.3 bits (64), Expect = 3.6
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 8/79 (10%)
Query: 57 DEKKEEAEVKPEVKIS----EKKKIAEKIKEKERQQKKRQEE----IKKRLEEPEEPKVL 108
+E K AEVK K E+ K EK K E+++ K E+ +K + PE+ K
Sbjct: 624 EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSP 683
Query: 109 TPEEQLADKLRLKKLQEES 127
E + + ++EE+
Sbjct: 684 VKAEAKSPEKAKSPVKEEA 702
Score = 28.5 bits (62), Expect = 6.1
Identities = 16/58 (27%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 57 DEKKEEAEVKPEVKISEKKKIA-EKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQ 113
+E+ EE +V EV E+K+ E+ KE+E +++ E ++ + P + +PE++
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKE 515
Score = 28.1 bits (61), Expect = 7.9
Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 6/74 (8%)
Query: 60 KEEAEVKPEVKISEKK------KIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQ 113
KEEA+ + K EK+ K +K + + +K + +K + PE+ K EE
Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA 702
Query: 114 LADKLRLKKLQEES 127
+ + ++EE+
Sbjct: 703 KSPEKAKSPVKEEA 716
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 47.4 bits (111), Expect = 1e-05
Identities = 36/111 (32%), Positives = 58/111 (52%), Gaps = 19/111 (17%)
Query: 40 EGEDEDEDV-----------KDNWDDDDDEKKEEAEVKPEVKIS--EKKKIAEKIKEKER 86
E +D DED K D EK+E+ E K + K++ EK+K EK++EKE+
Sbjct: 120 EDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEK 179
Query: 87 QQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFG 137
+KK K+++E+ E+P+ T LA + + K E+S+ + KE G
Sbjct: 180 PEKKATH--KEKIEKKEKPETKT----LAKEQKKAKTAEKSEEKTKKEVKG 224
Score = 38.9 bits (89), Expect = 0.004
Identities = 51/197 (25%), Positives = 89/197 (45%), Gaps = 27/197 (13%)
Query: 58 EKKEEAEVKPEVKISEKKKIAEKIKEKERQQKK--RQEEIKKRLEEPEE-PKVLTPEEQL 114
EKKE+ E K K +K K AEK +EK +++ K +QE++K+ + +E K + ++
Sbjct: 191 EKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEK 250
Query: 115 ADKLRLKKLQEESDLELAKETFGVNNAVYG------IDAMNP------SSRDDFTEFGKL 162
DK + + E + A + ++ V+G A+ P +SR T
Sbjct: 251 EDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRP--TPASPA 308
Query: 163 LKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKK 222
L++K + +K+ E V E +D+KK + T + EK ++ KA +
Sbjct: 309 LEEKEGEKKKA-------EKKVTSETKKKEKEDIKKKSEKETAIDVEK---KEPGKASET 358
Query: 223 KKGVVPGGGLKATMKDD 239
K+G V A KD+
Sbjct: 359 KQGTVKIAAQAAAKKDE 375
Score = 34.3 bits (77), Expect = 0.11
Identities = 58/203 (28%), Positives = 91/203 (44%), Gaps = 39/203 (19%)
Query: 44 EDEDVKDNWDDD---DDEKKEEAEVKPE----VKIS--------EKKKIAEKIK---EKE 85
E ED+K + + D EKKE + VKI+ EKK+ ++K K E E
Sbjct: 331 EKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVE 390
Query: 86 RQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGI 145
+ + K+QE+ +K +E + PK +DK Q ++ E AKE G I
Sbjct: 391 QPKGKKQEKKEKHVEPAKSPK--KEHSVPSDK------QVKAKTERAKEEIG----AVSI 438
Query: 146 DAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKKITNSLTV 205
P +++ T K ++ +I + EKS +S L+ ++ E +K+ SL
Sbjct: 439 KKAVPGKKEEKTT--KTVEQEIRK-EKSGKTSSILK--DKEPIKGKE----EKVPASLKE 489
Query: 206 LCSEKQKQEKQSKAKKKKKGVVP 228
E +K EK SKA K+ K P
Sbjct: 490 KEPETKKDEKMSKAGKEVKPKPP 512
Score = 28.5 bits (62), Expect = 6.1
Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 4/75 (5%)
Query: 64 EVKPEVKISEKKKIAE-KIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEE---QLADKLR 119
E + E K +EKK +E K KEKE +KK ++E +E+ E K ++ ++A +
Sbjct: 311 EKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAA 370
Query: 120 LKKLQEESDLELAKE 134
KK +++ D + K+
Sbjct: 371 AKKDEKKEDSKKTKK 385
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 46.6 bits (109), Expect = 2e-05
Identities = 23/88 (26%), Positives = 54/88 (61%), Gaps = 5/88 (5%)
Query: 43 DEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEP 102
+E+E+ ++ + +++E +EE E + E + E+K++ EKE ++KK++++ KK+ E
Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV-----EKEEEEKKKKKKEKKKEEVQ 2300
Query: 103 EEPKVLTPEEQLADKLRLKKLQEESDLE 130
E+ +V +E++ + + L +E + E
Sbjct: 2301 EKEEVFEEKEEIMSEEETESLSDEEEEE 2328
Score = 44.7 bits (104), Expect = 8e-05
Identities = 31/92 (33%), Positives = 54/92 (58%), Gaps = 6/92 (6%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQE-EIKKR 98
E E E+E+V++ ++++ +++EE E K K E+KK +K K+KE Q+K + E K+
Sbjct: 2254 EEEREEEEVRE--EEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEE 2311
Query: 99 LEEPEEPKVLTPEEQLADKLRLKKLQEESDLE 130
+ EE + L+ EE+ + L+EE D E
Sbjct: 2312 IMSEEETESLSDEEEEEESC---SLEEEVDRE 2340
Score = 43.1 bits (100), Expect = 2e-04
Identities = 52/204 (25%), Positives = 100/204 (49%), Gaps = 22/204 (10%)
Query: 39 WEGEDEDEDVKD-NWDDDDDEKKEEAEVKPEVK-ISEKKKIAEKIKEKERQQKKRQEEIK 96
W+ ++ +++++ WD ++ KEE + E K + EKKK+AE+ + Q++K EE
Sbjct: 1709 WQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEET 1768
Query: 97 KRLEEPE----------EPKVLTPEEQLADKLRLKKLQ-EESDLELAKETFGVNNAVYGI 145
K +E E + K PEE+ ++L K+ Q E ++LA++ N++ +
Sbjct: 1769 KLAQEEELLIQEKEKLAQHKEKMPEEE--ERLGRKREQLIEKKMKLAQKRERWINSMEEL 1826
Query: 146 --DAMNPSSRDDFTEFGKLL---KDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKKIT 200
+ M + + + K L K+K+ Q +++L Y E L +++ + +
Sbjct: 1827 TKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNK--ERLTHSKKQLVQVKNKLGMF 1884
Query: 201 NSLTVLCSEKQKQEKQSKAKKKKK 224
N + EK QEK++ KKK+K
Sbjct: 1885 NKILAQVEEKLTQEKETVIKKKEK 1908
Score = 42.4 bits (98), Expect = 4e-04
Identities = 25/92 (27%), Positives = 51/92 (55%)
Query: 43 DEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEP 102
DE E + ++++E++EE E + E E+++ E+ + +E+Q +K +EE KK+ +E
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294
Query: 103 EEPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
++ +V EE +K + +E L +E
Sbjct: 2295 KKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326
Score = 38.9 bits (89), Expect = 0.004
Identities = 26/99 (26%), Positives = 51/99 (51%), Gaps = 4/99 (4%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEE 101
+DE+E + + E+KE+ + + I E+ K A +++ R +KKR +E +K +E
Sbjct: 1539 KDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE 1598
Query: 102 PE----EPKVLTPEEQLADKLRLKKLQEESDLELAKETF 136
E E + L EE+ + +K Q++ ++ A+ F
Sbjct: 1599 EEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKF 1637
Score = 38.5 bits (88), Expect = 0.006
Identities = 23/105 (21%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
Query: 26 RKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKE 85
RK G +++ + ++ + ++++ ++ + +E E + + E+++ E+ + +E
Sbjct: 2200 RKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREE 2259
Query: 86 RQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLE 130
+ ++ +EE +K EE EE +V EE+ K + KK +E + E
Sbjct: 2260 EEVREEEEE-RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE 2303
Score = 35.8 bits (81), Expect = 0.038
Identities = 28/141 (19%), Positives = 69/141 (48%), Gaps = 9/141 (6%)
Query: 41 GEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKK-------RQE 93
G+ E D+ + E+ E++ + EK++ +E+ER++++ R+E
Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREE 2265
Query: 94 EIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSR 153
E +++ EE E K + EE+ +K + KK +++ +++ +E F + + S
Sbjct: 2266 EEERKEEEEGEEKQVEKEEE--EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSD 2323
Query: 154 DDFTEFGKLLKDKITQYEKSL 174
++ E L++++ + ++ L
Sbjct: 2324 EEEEEESCSLEEEVDREKEIL 2344
Score = 35.4 bits (80), Expect = 0.050
Identities = 21/89 (23%), Positives = 52/89 (58%), Gaps = 6/89 (6%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEE 101
E+E+ + K +++++KK++ E K E ++ EK+++ E E+++ +EE + +E
Sbjct: 2271 EEEEGEEKQVEKEEEEKKKKKKEKKKE-EVQEKEEVFE-----EKEEIMSEEETESLSDE 2324
Query: 102 PEEPKVLTPEEQLADKLRLKKLQEESDLE 130
EE + + EE++ + + K +++ L+
Sbjct: 2325 EEEEESCSLEEEVDREKEILKKEKQFKLQ 2353
Score = 34.7 bits (78), Expect = 0.085
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 20/104 (19%)
Query: 46 EDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQ-----------------Q 88
E+ K W++ K +E + K E +++ +++++ + +EKE+Q
Sbjct: 1519 EEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIH 1578
Query: 89 KKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELA 132
+KR KKR + EE K+ EE+LA + R + QEE L A
Sbjct: 1579 RKRARAEKKRAQ--EERKLAQEEEKLAQEER-QLAQEERKLAQA 1619
Score = 33.1 bits (74), Expect = 0.25
Identities = 51/194 (26%), Positives = 86/194 (44%), Gaps = 22/194 (11%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEK-KKIAEKIKEKERQQKKRQEEIKKR-- 98
E D+K+ WD EK+ E K E K++ K +K+A K++ +++K EE K
Sbjct: 2114 EQSKLDIKE-WDFS--EKRSEL-TKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLAR 2169
Query: 99 ------LEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSS 152
L++ EE + E K R +K +E + KE F +D + S
Sbjct: 2170 KHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQ-----VDEV--ES 2222
Query: 153 RDDFTEFGKLLKDKITQYE--KSLYYASFLEVLVRDVCISLEIDDLKKITNSLTVLCSEK 210
+ F+E + L D++ + E S E R+ E ++ +K EK
Sbjct: 2223 EEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK 2282
Query: 211 QKQEKQSKAKKKKK 224
+++EK+ K K+KKK
Sbjct: 2283 EEEEKKKKKKEKKK 2296
Score = 32.7 bits (73), Expect = 0.32
Identities = 32/172 (18%), Positives = 84/172 (48%), Gaps = 11/172 (6%)
Query: 59 KKEEAEVKPEVKISEKKKIAEKIKEK--ERQQKKRQEEIKKRLEEPEEPKVLTPEEQLAD 116
+++E +K + K++E +K ++++ ++Q+K QE++K LE+ ++ +++L
Sbjct: 1897 QEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEK----AMVQGKKRLRG 1952
Query: 117 KLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYY 176
+L + K ++ +LE+ + V G + ++ + + K+ + + +E+ L
Sbjct: 1953 ELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSL 2012
Query: 177 ASFLEVLVRDVCISLEIDDLKK----ITNSLTVLCSEKQKQEKQSKAKKKKK 224
+ +L D +++E ++ K T + ++K K S+ KK+
Sbjct: 2013 EEKI-LLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKR 2063
Score = 31.6 bits (70), Expect = 0.72
Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 4/75 (5%)
Query: 59 KKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKL 118
KK+ +VK K+ KI +++EK Q+K+ + K++L E E+ K++ E+ LA K
Sbjct: 1871 KKQLVQVKN--KLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEK-KLVQVEDSLAKK- 1926
Query: 119 RLKKLQEESDLELAK 133
+ K QE+ L L K
Sbjct: 1927 QEKLAQEKMKLALEK 1941
Score = 29.3 bits (64), Expect = 3.6
Identities = 19/78 (24%), Positives = 39/78 (50%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEE 101
E+E + K ++ ++KEE + E +SE++ + +E+E + +EE+ + E
Sbjct: 2284 EEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEI 2343
Query: 102 PEEPKVLTPEEQLADKLR 119
++ K +EQ LR
Sbjct: 2344 LKKEKQFKLQEQRRKSLR 2361
>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
Length = 259
Score = 46.2 bits (108), Expect = 3e-05
Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 16/130 (12%)
Query: 6 AAAGDSDSWDADAFSVEDPVRKVGGGGTAGGDRW------EGEDEDEDVKDNWDDDDDEK 59
A + D + D S+ GGG + + +D+DE+ D DDDDD
Sbjct: 123 AESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFD 182
Query: 60 KEEAEVKPEVKISEK---KKIAEKIKEKERQQK-------KRQEEIKKRLEEPEEPKVLT 109
EEAE K VK S + K A+K + + K K QE KK+ + P+ PK +
Sbjct: 183 DEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPS 242
Query: 110 PEEQLADKLR 119
E + K++
Sbjct: 243 SVEDIKAKMQ 252
>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
Length = 294
Score = 46.2 bits (108), Expect = 3e-05
Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 16/130 (12%)
Query: 6 AAAGDSDSWDADAFSVEDPVRKVGGGGTAGGDRW------EGEDEDEDVKDNWDDDDDEK 59
A + D + D S+ GGG + + +D+DE+ D DDDDD
Sbjct: 123 AESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFD 182
Query: 60 KEEAEVKPEVKISEK---KKIAEKIKEKERQQK-------KRQEEIKKRLEEPEEPKVLT 109
EEAE K VK S + K A+K + + K K QE KK+ + P+ PK +
Sbjct: 183 DEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPS 242
Query: 110 PEEQLADKLR 119
E + K++
Sbjct: 243 SVEDIKAKMQ 252
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 45.8 bits (107), Expect = 4e-05
Identities = 26/69 (37%), Positives = 40/69 (57%), Gaps = 7/69 (10%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
D E +D+DED +D+ D+DD+E++EE E +P + K+K KE ++K E K
Sbjct: 242 DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRK-------KEMAKQKAAPEAK 294
Query: 97 KRLEEPEEP 105
K+ E EP
Sbjct: 295 KQKVEGTEP 303
Score = 43.9 bits (102), Expect = 1e-04
Identities = 34/132 (25%), Positives = 59/132 (44%), Gaps = 16/132 (12%)
Query: 10 DSDSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEV 69
D + D D +E K A D E +++DED +D+ DD++D+ +EEA
Sbjct: 159 DDEDEDEDEDEIEPAAMKAAAAAPASED--EDDEDDEDDEDDDDDEEDDSEEEAMETTPA 216
Query: 70 KISEKKKI----AEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQE 125
K + K+ A+ + E E +++ ++E E+ E+ EE+ +E
Sbjct: 217 KGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEE----------EE 266
Query: 126 ESDLELAKETFG 137
E + E KE G
Sbjct: 267 EEEEEPVKEAPG 278
Score = 37.7 bits (86), Expect = 0.010
Identities = 23/93 (24%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEE 101
E+ED+D +++ +DD+DE ++E E++P + A + ++ E + ++ + +
Sbjct: 147 EEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDS 206
Query: 102 PEEPKVLTPEE-QLADK---LRLKKLQEESDLE 130
EE TP + + A K ++ K + E+ D E
Sbjct: 207 EEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEE 239
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 45.8 bits (107), Expect = 4e-05
Identities = 44/176 (25%), Positives = 95/176 (53%), Gaps = 18/176 (10%)
Query: 59 KKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPK--VLTPEEQLAD 116
K++EA+++ + + +K++ E+ + KE ++K+++EE K+R +E EE K V EQL
Sbjct: 322 KEKEAKIRQKEE-ENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLIS 380
Query: 117 KLRLKKLQEESDLEL----AKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEK 172
K ++ L+E++ +L A + G NN ++ ++ +D + K L D+ ++ ++
Sbjct: 381 KEKI-ILREDASQQLIISSALKKSGYNNKHLSLEDIS----NDKGDIAKNLVDENSKKQE 435
Query: 173 SLYY-----ASFLEVLVRDVCISLEID-DLKKITNSLTVLCSEKQKQEKQSKAKKK 222
+ ++ E + R + I LK+ +S T+L K +++ ++ AKK+
Sbjct: 436 DVLLWLVEESNMKENVDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKR 491
Score = 31.6 bits (70), Expect = 0.72
Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 16/92 (17%)
Query: 55 DDDEKKEEAEVKPE----VKISEKKK-----------IAEKIKEKERQ-QKKRQEEIKKR 98
D EK++ + +K + VKI K K I E+I+ K+R+ Q+ +++E K R
Sbjct: 270 DQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIR 329
Query: 99 LEEPEEPKVLTPEEQLADKLRLKKLQEESDLE 130
+E E K L E+++ ++ + +K +E E
Sbjct: 330 QKEEENRKRLEEEQRIKEERKKQKEEERKRRE 361
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 45.8 bits (107), Expect = 4e-05
Identities = 44/176 (25%), Positives = 95/176 (53%), Gaps = 18/176 (10%)
Query: 59 KKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPK--VLTPEEQLAD 116
K++EA+++ + + +K++ E+ + KE ++K+++EE K+R +E EE K V EQL
Sbjct: 322 KEKEAKIRQKEE-ENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLIS 380
Query: 117 KLRLKKLQEESDLEL----AKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEK 172
K ++ L+E++ +L A + G NN ++ ++ +D + K L D+ ++ ++
Sbjct: 381 KEKI-ILREDASQQLIISSALKKSGYNNKHLSLEDIS----NDKGDIAKNLVDENSKKQE 435
Query: 173 SLYY-----ASFLEVLVRDVCISLEID-DLKKITNSLTVLCSEKQKQEKQSKAKKK 222
+ ++ E + R + I LK+ +S T+L K +++ ++ AKK+
Sbjct: 436 DVLLWLVEESNMKENVDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKR 491
Score = 31.6 bits (70), Expect = 0.72
Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 16/92 (17%)
Query: 55 DDDEKKEEAEVKPE----VKISEKKK-----------IAEKIKEKERQ-QKKRQEEIKKR 98
D EK++ + +K + VKI K K I E+I+ K+R+ Q+ +++E K R
Sbjct: 270 DQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIR 329
Query: 99 LEEPEEPKVLTPEEQLADKLRLKKLQEESDLE 130
+E E K L E+++ ++ + +K +E E
Sbjct: 330 QKEEENRKRLEEEQRIKEERKKQKEEERKRRE 361
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 45.8 bits (107), Expect = 4e-05
Identities = 25/117 (21%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEE 101
E+E ED ++ + +D+D++ + + + + +++KEKE ++ K++EE+KK+ E+
Sbjct: 335 EEESED-EEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
Query: 102 PEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTE 158
EE + +++ +++R K +E + E G +P + + + E
Sbjct: 394 EEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGE 450
Score = 40.4 bits (93), Expect = 0.002
Identities = 19/69 (27%), Positives = 44/69 (63%), Gaps = 2/69 (2%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIA--EKIKEKERQQKKRQEE 94
+ + EDED++ + + D++K + E+K E++++ E++K+KE ++++ +EE
Sbjct: 341 EEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEE 400
Query: 95 IKKRLEEPE 103
+K++ EE E
Sbjct: 401 MKQKEEEEE 409
Score = 34.3 bits (77), Expect = 0.11
Identities = 25/91 (27%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEE 101
E E+E++K + E+KEE E + E+K E+++ E+E + K ++E + ++
Sbjct: 375 EKEEEEMKKEEEMKKKEEKEEEE-EEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQK 433
Query: 102 PE-EPKVLTPEEQLADKLRLKKLQEESDLEL 131
PE EP+ E+ ++ + L E D +L
Sbjct: 434 PEGEPQQDPGTEETYGEVEEEPLDEAQDDDL 464
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 45.4 bits (106), Expect = 5e-05
Identities = 31/112 (27%), Positives = 55/112 (49%), Gaps = 11/112 (9%)
Query: 54 DDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQ 113
+DD KKE+ E KKK EK+K +E +KK +EE KK EE + + + Q
Sbjct: 61 EDDKRKKEDKE--------RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ 112
Query: 114 LADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMN---PSSRDDFTEFGKL 162
++ + ++E ++L +E + ++ + + N P SR + F +L
Sbjct: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRL 164
Score = 42.7 bits (99), Expect = 3e-04
Identities = 24/68 (35%), Positives = 41/68 (60%), Gaps = 2/68 (2%)
Query: 46 EDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEP 105
ED K +D + +KK+E +VK E + KKK E+ K+ + +++K+QEE KR +E E
Sbjct: 61 EDDKRKKEDKERKKKDEEKVKAEEE--SKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA 118
Query: 106 KVLTPEEQ 113
+ +E+
Sbjct: 119 AQMKEKEE 126
Score = 38.5 bits (88), Expect = 0.006
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 12/78 (15%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
D+ + ED++ +KK+E +VK E + S+KK+ EK K +E ++KK++E+ K
Sbjct: 63 DKRKKEDKER-----------KKKDEEKVKAEEE-SKKKEEEEKKKHQEEERKKQEEQAK 110
Query: 97 KRLEEPEEPKVLTPEEQL 114
++ EE ++ EE +
Sbjct: 111 RQQEEEAAAQMKEKEESI 128
Score = 37.7 bits (86), Expect = 0.010
Identities = 24/89 (26%), Positives = 49/89 (55%), Gaps = 5/89 (5%)
Query: 43 DEDEDVKDNWDDDDDEKK---EEAEVKPEVKISEKKKI--AEKIKEKERQQKKRQEEIKK 97
+E + + +N + D E++ + K ++K++ KK++ A + K+K + KR++E K+
Sbjct: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
Query: 98 RLEEPEEPKVLTPEEQLADKLRLKKLQEE 126
R ++ EE E + ++ KK QEE
Sbjct: 72 RKKKDEEKVKAEEESKKKEEEEKKKHQEE 100
Score = 37.0 bits (84), Expect = 0.017
Identities = 40/138 (28%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Query: 38 RWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQ-EEIK 96
R E + ++ K+ D+++ K E E K + + +KK E+ K++E Q K++Q EE
Sbjct: 59 RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA 118
Query: 97 KRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDF 156
+++E EE L E LR K+L+ ++ + A ++ N +D SS
Sbjct: 119 AQMKEKEESIQLHQEAWERHHLR-KELRSKN--QNAPDSRPEENFFSRLD----SSLKKN 171
Query: 157 TEFGKLLKDKITQYEKSL 174
T F K LK Q SL
Sbjct: 172 TAFVKKLKTITEQQRDSL 189
Score = 35.8 bits (81), Expect = 0.038
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 9/88 (10%)
Query: 53 DDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLE------EPEEPK 106
DD K+E PE K KK++ + ++KE +++K+++E K + E E EE K
Sbjct: 39 DDIKLTAKKEVSKAPEDK---KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKK 95
Query: 107 VLTPEEQLADKLRLKKLQEESDLELAKE 134
EE+ + + K+ QEE KE
Sbjct: 96 KHQEEERKKQEEQAKRQQEEEAAAQMKE 123
Score = 33.9 bits (76), Expect = 0.14
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 15/110 (13%)
Query: 22 EDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKI 81
ED + GG T E E + + ++ D+DDDE +EE E + + +
Sbjct: 1031 EDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDY-------LTDSN 1083
Query: 82 KEKERQQKKRQEEIK----KRLEEPEEPKVLTPEEQLADKLRLKKLQEES 127
KE E ++ + IK K + E+ + Q DK+ L+ LQ+ S
Sbjct: 1084 KENETDEENTEVMIKGGGLKHVPCVEDEDFI----QALDKMMLENLQQRS 1129
Score = 28.9 bits (63), Expect = 4.6
Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 24/145 (16%)
Query: 22 EDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKI 81
ED RK + + E+E+ K + +++ KK+E + K + ++++ A ++
Sbjct: 68 EDKERKKKDEEKVKAEEESKKKEEEEKKKH--QEEERKKQEEQAKRQ----QEEEAAAQM 121
Query: 82 KEKERQQKKRQE-----EIKKRL-EEPEEPKVLTPEEQLADKL------------RLKKL 123
KEKE + QE ++K L + + PEE +L +LK +
Sbjct: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTI 181
Query: 124 QEESDLELAKETFGVNNAVYGIDAM 148
E+ L+ + G+N + Y +A+
Sbjct: 182 TEQQRDSLSHDFNGLNLSKYIAEAV 206
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 45.4 bits (106), Expect = 5e-05
Identities = 31/112 (27%), Positives = 55/112 (49%), Gaps = 11/112 (9%)
Query: 54 DDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQ 113
+DD KKE+ E KKK EK+K +E +KK +EE KK EE + + + Q
Sbjct: 61 EDDKRKKEDKE--------RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ 112
Query: 114 LADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMN---PSSRDDFTEFGKL 162
++ + ++E ++L +E + ++ + + N P SR + F +L
Sbjct: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRL 164
Score = 42.7 bits (99), Expect = 3e-04
Identities = 24/68 (35%), Positives = 41/68 (60%), Gaps = 2/68 (2%)
Query: 46 EDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEP 105
ED K +D + +KK+E +VK E + KKK E+ K+ + +++K+QEE KR +E E
Sbjct: 61 EDDKRKKEDKERKKKDEEKVKAEEE--SKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA 118
Query: 106 KVLTPEEQ 113
+ +E+
Sbjct: 119 AQMKEKEE 126
Score = 38.5 bits (88), Expect = 0.006
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 12/78 (15%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
D+ + ED++ +KK+E +VK E + S+KK+ EK K +E ++KK++E+ K
Sbjct: 63 DKRKKEDKER-----------KKKDEEKVKAEEE-SKKKEEEEKKKHQEEERKKQEEQAK 110
Query: 97 KRLEEPEEPKVLTPEEQL 114
++ EE ++ EE +
Sbjct: 111 RQQEEEAAAQMKEKEESI 128
Score = 37.7 bits (86), Expect = 0.010
Identities = 24/89 (26%), Positives = 49/89 (55%), Gaps = 5/89 (5%)
Query: 43 DEDEDVKDNWDDDDDEKK---EEAEVKPEVKISEKKKI--AEKIKEKERQQKKRQEEIKK 97
+E + + +N + D E++ + K ++K++ KK++ A + K+K + KR++E K+
Sbjct: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
Query: 98 RLEEPEEPKVLTPEEQLADKLRLKKLQEE 126
R ++ EE E + ++ KK QEE
Sbjct: 72 RKKKDEEKVKAEEESKKKEEEEKKKHQEE 100
Score = 37.0 bits (84), Expect = 0.017
Identities = 40/138 (28%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Query: 38 RWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQ-EEIK 96
R E + ++ K+ D+++ K E E K + + +KK E+ K++E Q K++Q EE
Sbjct: 59 RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA 118
Query: 97 KRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDF 156
+++E EE L E LR K+L+ ++ + A ++ N +D SS
Sbjct: 119 AQMKEKEESIQLHQEAWERHHLR-KELRSKN--QNAPDSRPEENFFSRLD----SSLKKN 171
Query: 157 TEFGKLLKDKITQYEKSL 174
T F K LK Q SL
Sbjct: 172 TAFVKKLKTITEQQRDSL 189
Score = 35.8 bits (81), Expect = 0.038
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 9/88 (10%)
Query: 53 DDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLE------EPEEPK 106
DD K+E PE K KK++ + ++KE +++K+++E K + E E EE K
Sbjct: 39 DDIKLTAKKEVSKAPEDK---KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKK 95
Query: 107 VLTPEEQLADKLRLKKLQEESDLELAKE 134
EE+ + + K+ QEE KE
Sbjct: 96 KHQEEERKKQEEQAKRQQEEEAAAQMKE 123
Score = 33.9 bits (76), Expect = 0.14
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 15/110 (13%)
Query: 22 EDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKI 81
ED + GG T E E + + ++ D+DDDE +EE E + + +
Sbjct: 1031 EDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDY-------LTDSN 1083
Query: 82 KEKERQQKKRQEEIK----KRLEEPEEPKVLTPEEQLADKLRLKKLQEES 127
KE E ++ + IK K + E+ + Q DK+ L+ LQ+ S
Sbjct: 1084 KENETDEENTEVMIKGGGLKHVPCVEDEDFI----QALDKMMLENLQQRS 1129
Score = 28.9 bits (63), Expect = 4.6
Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 24/145 (16%)
Query: 22 EDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKI 81
ED RK + + E+E+ K + +++ KK+E + K + ++++ A ++
Sbjct: 68 EDKERKKKDEEKVKAEEESKKKEEEEKKKH--QEEERKKQEEQAKRQ----QEEEAAAQM 121
Query: 82 KEKERQQKKRQE-----EIKKRL-EEPEEPKVLTPEEQLADKL------------RLKKL 123
KEKE + QE ++K L + + PEE +L +LK +
Sbjct: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTI 181
Query: 124 QEESDLELAKETFGVNNAVYGIDAM 148
E+ L+ + G+N + Y +A+
Sbjct: 182 TEQQRDSLSHDFNGLNLSKYIAEAV 206
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 45.1 bits (105), Expect = 6e-05
Identities = 41/147 (27%), Positives = 73/147 (49%), Gaps = 16/147 (10%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKE------RQQKKRQEEI 95
E + DVK + KKE +VKPE K EK+K +++ +KE +++K ++EE+
Sbjct: 622 EKQATDVKPKAAKEKTVKKE-TKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEV 680
Query: 96 KKRL------EEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMN 149
KK + EE +EPK +E +++ K++++E E+ KE + +
Sbjct: 681 KKEVKKEIKKEEKKEPKKEVKKETPPKEVK-KEVKKEEKKEVKKEEKEPKKEIKKLPKDA 739
Query: 150 PSSRDDFTEFGK--LLKDKITQYEKSL 174
S +E K LK K+ + E+S+
Sbjct: 740 KKSSTPLSEAKKPAALKPKVPKKEESV 766
Score = 40.4 bits (93), Expect = 0.002
Identities = 26/94 (27%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQ---E 93
D+ E +++ + +D KKEE K EVK KK+I ++ K++ +++ K++ +
Sbjct: 648 DKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPK 707
Query: 94 EIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEES 127
E+KK +++ E+ +V +E+ K +KKL +++
Sbjct: 708 EVKKEVKKEEKKEV--KKEEKEPKKEIKKLPKDA 739
Score = 33.9 bits (76), Expect = 0.14
Identities = 30/116 (25%), Positives = 57/116 (49%), Gaps = 21/116 (18%)
Query: 40 EGEDEDEDVKDNWDDD---DDEKKEE---------AEVKPEVKISEKKKIAEKIKEKERQ 87
E + + E+VK + +++K+ + EVK EVK EKK++ ++ KE +++
Sbjct: 672 EEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKE 731
Query: 88 QKKRQEEIKKR---LEEPEEPKVLTP------EEQLADKLRLKKLQEESDLELAKE 134
KK ++ KK L E ++P L P E D + K +E+ +++ K+
Sbjct: 732 IKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKK 787
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 44.7 bits (104), Expect = 8e-05
Identities = 32/101 (31%), Positives = 57/101 (56%), Gaps = 2/101 (1%)
Query: 32 GTAGGDRWEGEDEDEDVKD-NWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKK 90
GT GG +ED V + N D+++E++EE E + E + E++ E+ +++E ++
Sbjct: 864 GTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEE 923
Query: 91 RQEEIKKRLEE-PEEPKVLTPEEQLADKLRLKKLQEESDLE 130
+EE ++ EE EE L EE+ D+ ++L+E DLE
Sbjct: 924 EEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE 964
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 43.9 bits (102), Expect = 1e-04
Identities = 57/236 (24%), Positives = 98/236 (41%), Gaps = 31/236 (13%)
Query: 26 RKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDD--EKKEEAEVKPEVKISEKKKIAEKIKE 83
RK G AG D+ E E K + + + ++K+ A V K+K+ EK ++
Sbjct: 1185 RKDRGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEK 1244
Query: 84 KERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVY 143
K + K + + K++ ++ + + A+K L+KL+EE+ E +++
Sbjct: 1245 KHAAEDKAKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDS-------- 1296
Query: 144 GIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKKITNSL 203
D ++ S D FT+ G+ E L +FLEV + DD + + L
Sbjct: 1297 -NDKISEVSSDSFTDRGQ---------EPGL--TAFLEVSFTEP----PGDDKPRESACL 1340
Query: 204 TVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADY--GGY---DGGYVQDY 254
EK++ S + KK KA K+ DY GG G Y +D+
Sbjct: 1341 PEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEGGSRKDSGQYEKDF 1396
Score = 31.6 bits (70), Expect = 0.72
Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 15/119 (12%)
Query: 15 DADAFSVEDPVRKVGGGGTAGGDRWEGEDED--EDVKDNWDDDD----DEKKEEAEVKPE 68
D D F E+ + K+ W +DE + +KD D +EK + + E
Sbjct: 690 DRDHFKKEEKLSKM----KLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKE 745
Query: 69 VKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEP---EEPKVLTPEEQL--ADKLRLKK 122
+ EK EK++ + ++KK+ ++ +LE+ +E K+ +E++ DK +LKK
Sbjct: 746 RSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKK 804
Score = 30.4 bits (67), Expect = 1.6
Identities = 46/188 (24%), Positives = 75/188 (39%), Gaps = 34/188 (18%)
Query: 68 EVKISEKKKIAEKIKEKERQQKKRQEEIKKRL-------EEPEEPKVLTPEEQLADKLRL 120
E K+ +K K K K KE+ Q +E+K + + + K + E L+ + +L
Sbjct: 625 EGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKL 684
Query: 121 KKLQEESD------------LELAKETFGVNNAVYGIDAMN---------PSSRDDFTEF 159
K L+ + D LE + F ++ I N R + E
Sbjct: 685 KVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEK 744
Query: 160 GKLLKDKITQYEKSLYYASFLEVLVRDVCISLE-IDDLKKITNSLTVLCSEKQKQEKQSK 218
+ LK+K + EK Y + +D LE +DLK+ + EK+K K+ K
Sbjct: 745 ERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKE-----DKISKEKEKIFKEDK 799
Query: 219 AKKKKKGV 226
K KK+ V
Sbjct: 800 EKLKKEKV 807
Score = 30.0 bits (66), Expect = 2.1
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 5/51 (9%)
Query: 49 KDNWDDD-DDEKKEEAEVKP----EVKISEKKKIAEKIKEKERQQKKRQEE 94
KD D + + KK E E+KP + I ++KK EK +EK R +K+R +
Sbjct: 1428 KDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWRDEKERHRD 1478
Score = 29.3 bits (64), Expect = 3.6
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 16/142 (11%)
Query: 27 KVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPE---VKISEKKKIAEKIKE 83
K G G + WE + K+ D D E+KE+ KPE K S+K K + I E
Sbjct: 988 KSDGDFGKGLEPWERHHPARE-KEKKDGPDKERKEKT--KPERYKEKSSDKDKSEKSILE 1044
Query: 84 KERQQKKRQEEIKKRLEEPEEPKVL--TPEEQLADKLRLKKLQEESDLELAKETF----- 136
K ++ K+ + K++ + E+ K +E+ A + K+ +E++ + E F
Sbjct: 1045 KCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKD 1104
Query: 137 ---GVNNAVYGIDAMNPSSRDD 155
G + Y D S DD
Sbjct: 1105 DKKGKEKSWYIADIFTDESEDD 1126
Score = 28.9 bits (63), Expect = 4.6
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 49 KDNWDDDDDEKKEEAEVKPEVK--ISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPK 106
+D D + +++KE+ E V +SEK K + E R +K E K+R + +P+
Sbjct: 910 RDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPE 969
Query: 107 VLTPEE 112
EE
Sbjct: 970 EAHREE 975
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 43.5 bits (101), Expect = 2e-04
Identities = 39/174 (22%), Positives = 77/174 (44%), Gaps = 40/174 (22%)
Query: 56 DDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEE-----PEEPKVLTP 110
+++K+E+ E++ K ++ + +KE +++KRQEEI+++ E P+EP ++
Sbjct: 673 EEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIV- 731
Query: 111 EEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQY 170
+ + + M+ S D+ +L +K +
Sbjct: 732 ----------------------HPNWAAKSGKFDCSIMSLSVLLDY----RLEDNKEHSF 765
Query: 171 EKSLYYASFLEVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKK 224
E SL+ F E+L RD + +I SL L ++ K+EK K+KK ++
Sbjct: 766 EVSLFAELFNEMLQRDFGV--------RIYKSLLSLPEKEDKKEKDKKSKKDER 811
Score = 36.2 bits (82), Expect = 0.029
Identities = 22/90 (24%), Positives = 51/90 (56%), Gaps = 2/90 (2%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVK-PEVKISEKKKIAEKIKEKERQQKKRQEEIKKR 98
E ED+ E K + D+ +KKEE + + E K +K +K K+++R ++K++++ K
Sbjct: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
Query: 99 LEEPEEPKVLTPEEQLADKLRLKKLQEESD 128
++ +E + +++ D + ++ ++E D
Sbjct: 855 SKDDDETEEDNNQDEY-DPMEAEEAEDEED 883
Score = 36.2 bits (82), Expect = 0.029
Identities = 21/97 (21%), Positives = 49/97 (50%), Gaps = 4/97 (4%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDE----KKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQ 92
D+ +DE +D K+ DD+ DE +++ + K + + +++K +K K+ + + +
Sbjct: 803 DKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETE 862
Query: 93 EEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDL 129
E+ + +P E + EE D+ + K ++ D+
Sbjct: 863 EDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDI 899
Score = 28.9 bits (63), Expect = 4.6
Identities = 18/76 (23%), Positives = 35/76 (46%)
Query: 26 RKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKE 85
RK G DR E + ED+ D+ DDD+ E+ + ++ E + + E+E
Sbjct: 830 RKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEE 889
Query: 86 RQQKKRQEEIKKRLEE 101
++ + +I + +E
Sbjct: 890 MTKRDDKRDINRYCKE 905
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/122 (23%), Positives = 63/122 (51%), Gaps = 15/122 (12%)
Query: 26 RKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDE---KKEEAEVKPEVKISEKKKIAEKIK 82
R+ GGG GG+ E E+E E+ ++ DD DD ++E+ E++ + + +AE+
Sbjct: 383 RREGGGSGGGGE--EEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKM 440
Query: 83 EKERQQKKRQEEIKKRLEEPE---------EPKVLTPEEQLADKL-RLKKLQEESDLELA 132
++++K+ E++++ + E E K+L + + D +K+ E+ E+A
Sbjct: 441 RLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIA 500
Query: 133 KE 134
++
Sbjct: 501 EQ 502
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 43.5 bits (101), Expect = 2e-04
Identities = 24/101 (23%), Positives = 56/101 (55%), Gaps = 6/101 (5%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRL 99
E + E K WD ++ ++EE + E K+ E++++ + +EK ++Q+++ E ++++
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Query: 100 EEPE------EPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
E E E K+ EE++ ++ K+QE+ ++ +E
Sbjct: 598 WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638
Score = 42.7 bits (99), Expect = 3e-04
Identities = 28/98 (28%), Positives = 60/98 (61%), Gaps = 8/98 (8%)
Query: 39 WEGEDEDEDVKDN-WDDDDDEKKEEAEVKP-EVKISEKKKIAEKIKEKERQQKKRQEEIK 96
WE E++ D + WD ++ +++ ++ E ++ E+KK+ ++ +EK R++KK QE+ K
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ-EEKMREEKKTQEQEK 547
Query: 97 KRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
K ++ E+ + EE++ + R KK++EE ++ +E
Sbjct: 548 KTWDQEEK---MREEERMRE--REKKMREEEEMMREQE 580
Score = 39.3 bits (90), Expect = 0.003
Identities = 28/137 (20%), Positives = 72/137 (52%), Gaps = 11/137 (8%)
Query: 39 WEGEDED---EDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEI 95
WE E+ED E + W+ + EK +E E K + + ++ EK++E+E + + ++E++
Sbjct: 619 WEQEEEDKMQEQEEMMWEQE--EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 676
Query: 96 KKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDD 155
++ +E K+ EE++ ++ + QEE ++ +G ++G + M +
Sbjct: 677 RE-----QEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMR-EKEER 730
Query: 156 FTEFGKLLKDKITQYEK 172
+ + +++++ ++E+
Sbjct: 731 IRDQKEKMQERLPEHEE 747
Score = 38.9 bits (89), Expect = 0.004
Identities = 25/117 (21%), Positives = 63/117 (53%), Gaps = 12/117 (10%)
Query: 39 WEGEDEDEDVKDN--------WDDDDDEKKEEAEV---KPEVKISEKKKIAEKIKEKERQ 87
WE E++ ++ ++ W+ ++++K +E E + E K+ E+++ + +EK R+
Sbjct: 598 WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 657
Query: 88 QKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYG 144
Q+++ E +++++ EE K+ EE++ + + QEE ++ +G ++G
Sbjct: 658 QEEKMREQEEKMQGQEE-KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWG 713
Score = 37.0 bits (84), Expect = 0.017
Identities = 24/99 (24%), Positives = 56/99 (56%), Gaps = 7/99 (7%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKE---RQQKKRQEEI 95
W+ E++ + K + + +E +++ E ++ E++K K++E+E R+Q+++ +E
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK---KMREEEEMMREQEEKMQEQ 586
Query: 96 KKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
++++ E EE K+ EE++ ++ QEE E +E
Sbjct: 587 EEKMREQEE-KMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624
Score = 35.8 bits (81), Expect = 0.038
Identities = 25/101 (24%), Positives = 57/101 (56%), Gaps = 13/101 (12%)
Query: 39 WEGE----DEDEDVKDN----WDDDDDEKKEEAEVKPEVKISEKK-KIAEKIKEKERQQK 89
WE E ++++ ++D W+ D+ +++E ++ + K+ E++ K+ E+ + +ER++K
Sbjct: 341 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400
Query: 90 KRQEEIKKRLEE----PEEPKVLTPEEQLADKLRLKKLQEE 126
R+EE R +E +E + EE+ + RL + +E+
Sbjct: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
Score = 34.3 bits (77), Expect = 0.11
Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 9/102 (8%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
+ W E+E + + K+EE + E ++ E++ + +EK R+Q+KR E +
Sbjct: 235 EMWRQEEELRE-----QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289
Query: 97 KRLEEPE----EPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
K L E E E K L +E+ + K ++E + +E
Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331
Score = 34.3 bits (77), Expect = 0.11
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 8/93 (8%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR 98
WE E++ D ++ W + ++E + E ++ E+++ ++K Q++R E +R
Sbjct: 456 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
Query: 99 LEEPEE-----PKVLTPEEQLADKLRLKKLQEE 126
L E EE K+ EE++ ++ KK QE+
Sbjct: 516 LREKEERMREQKKMWQQEEKMREE---KKTQEQ 545
Score = 33.9 bits (76), Expect = 0.14
Identities = 21/87 (24%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRL 99
EG+ +++ K + ++E+ + E ++ E+KK+ E+ ++ + Q++K E+ +K
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327
Query: 100 EEPEEPKVLTPEEQLADKLRLKKLQEE 126
E +E K+ EE+L ++ + + QE+
Sbjct: 328 E--QEEKMWRQEERLWEQEKQMREQEQ 352
Score = 33.5 bits (75), Expect = 0.19
Identities = 27/101 (26%), Positives = 57/101 (56%), Gaps = 14/101 (13%)
Query: 39 WEGED----EDEDVKDNWDDDDDEKK---EEAEVKPEVKISEKKKIA----EKIKEKE-- 85
W+ E+ +DE +++ + ++KK +E +++ E K E++K EK++E+E
Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 86 RQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEE 126
R+++K+ E ++ + E EE K+ EE++ ++ QEE
Sbjct: 563 REREKKMREEEEMMREQEE-KMQEQEEKMREQEEKMWEQEE 602
Score = 32.7 bits (73), Expect = 0.32
Identities = 23/99 (23%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR 98
W+ + E + W+ + +++EE + E KI +++++ + K+ RQ+K R++E +
Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
Query: 99 LEE----PEEPKVLTPEEQLADKLRLKKLQEESDLELAK 133
+E +E K+ EE++ ++ + +EE E K
Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKK 528
Score = 32.3 bits (72), Expect = 0.42
Identities = 23/90 (25%), Positives = 53/90 (58%), Gaps = 7/90 (7%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRL 99
E E+ + + W+ ++ ++EE + E K+ E++ E ++E+E + +K++E + ++
Sbjct: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEE---ETMREQEEKMQKQEENMWEQ- 425
Query: 100 EEPEEPKVLTPEEQLADKL-RLKKLQEESD 128
EE E + PE++ +KL +K+QE+ +
Sbjct: 426 EEKEWQQQRLPEQK--EKLWEQEKMQEQEE 453
Score = 30.8 bits (68), Expect = 1.2
Identities = 25/105 (23%), Positives = 54/105 (51%), Gaps = 15/105 (14%)
Query: 39 WEGEDE-DEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKK 97
WE E++ E+ + + ++EE + E K+ ++++ + +EKE QQ++ E+ +K
Sbjct: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
Query: 98 RLE----EPEEPKVLTPEEQLADK----------LRLKKLQEESD 128
E + +E K+ EE++ D+ R +K++E+ D
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486
Score = 30.8 bits (68), Expect = 1.2
Identities = 23/123 (18%), Positives = 63/123 (51%), Gaps = 20/123 (16%)
Query: 42 EDEDEDVKDN----WDDDDDEKKEEA----------EVKPEVKISEKKKIAEKIKEKERQ 87
++++E +++ W+ ++ +++E E + E K+ E++++ + +EK ++
Sbjct: 584 QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQE 643
Query: 88 QKKRQEEIKKRLEEPE------EPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNA 141
Q+++ E ++++ E E E K+ EE++ ++ + QEE E ++ G
Sbjct: 644 QEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEK 703
Query: 142 VYG 144
++G
Sbjct: 704 MWG 706
Score = 30.4 bits (67), Expect = 1.6
Identities = 24/101 (23%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Query: 43 DEDEDVKDNWD--DDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLE 100
+E+E +++ + + +EK E E K + + ++ EK+ E+E + +++EE K + +
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ 630
Query: 101 EP----EEPKVLTPEEQLADKLRLKKLQEESDLELAKETFG 137
E +E K+ EE++ ++ + QEE E ++ G
Sbjct: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 671
Score = 30.0 bits (66), Expect = 2.1
Identities = 18/92 (19%), Positives = 57/92 (61%), Gaps = 7/92 (7%)
Query: 39 WEGEDEDEDVKDN-WDDDDDEKKEEAEVKP-EVKISEKKKIAEKIKEKERQQKKRQEEIK 96
WE E++ + ++ W ++ ++E +++ E K+ +++ E++ E++ + ++++E ++
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE---ERMWEQDERLREKEERMR 376
Query: 97 KRLEEPEEPKVLTPEEQLADKLRLKKLQEESD 128
++ + E+ + + EE++ + R KK++EE +
Sbjct: 377 EQEKMWEQEEKMQEEERIRE--REKKMREEEE 406
Score = 29.3 bits (64), Expect = 3.6
Identities = 21/85 (24%), Positives = 50/85 (58%), Gaps = 6/85 (7%)
Query: 48 VKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQ--KKRQEEIKKRLEE---- 101
V+ N ++ ++EE + E KI ++++ + +E+ R+Q K R++E K R +E
Sbjct: 227 VQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLR 286
Query: 102 PEEPKVLTPEEQLADKLRLKKLQEE 126
+E ++ E++L ++ +L++ +E+
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQ 311
Score = 28.5 bits (62), Expect = 6.1
Identities = 17/74 (22%), Positives = 44/74 (59%), Gaps = 2/74 (2%)
Query: 55 DDDEKKEEAEVKPEVKI--SEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEE 112
+++ KK+ AE++ ++++ SEK +I +KE +R+ ++ + + + + ++ EE
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 113 QLADKLRLKKLQEE 126
+L ++ + + QEE
Sbjct: 242 ELREQEKKIRKQEE 255
Score = 28.5 bits (62), Expect = 6.1
Identities = 18/81 (22%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 46 EDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEP 105
E K ++ +++EE + E K+ E+++ + +E+ +Q+K+ E ++++ + EE
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE- 359
Query: 106 KVLTPEEQLADKLRLKKLQEE 126
++ +E+L +K + QE+
Sbjct: 360 RMWEQDERLREKEERMREQEK 380
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 43.5 bits (101), Expect = 2e-04
Identities = 36/147 (24%), Positives = 70/147 (47%), Gaps = 24/147 (16%)
Query: 4 AAAAAGDSDSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDD-----DD- 57
A++ + D DS + E V ++ + EDE+ D + +D +D
Sbjct: 134 ASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDR 193
Query: 58 -------EKKEEAEV----------KPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLE 100
EK+ E E+ K +I +K K A+K ++KE+++K+ +E+ KK+L
Sbjct: 194 ARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLT 253
Query: 101 EPEEPKVLTPEEQLADKLRLKKLQEES 127
+ +E +V + ++ K R +KL ++S
Sbjct: 254 QIQESQVTSHNKERRSK-RDEKLDKKS 279
Score = 29.3 bits (64), Expect = 3.6
Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 4/91 (4%)
Query: 44 EDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPE 103
+++ K +++ EKK+ +++ S K+ K EK ++ + EE+K E+ +
Sbjct: 234 KEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRK 293
Query: 104 EPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
E LA K LK + SD E +E
Sbjct: 294 N----RTAELLAKKQPLKTSEVYSDDEEEEE 320
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 43.5 bits (101), Expect = 2e-04
Identities = 34/108 (31%), Positives = 59/108 (54%), Gaps = 9/108 (8%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKP----EVKISEKKKIAEKIKEKERQQKKRQ 92
+R E E E+ K ++ +K+EE E+K E + ++K+ AEK + KE ++K+RQ
Sbjct: 353 EREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQ 412
Query: 93 EEIKKRLEE---PEEPKVLTPEEQ--LADKLRLKKLQEESDLELAKET 135
E ++ +LEE EE K L EE+ A+K + + ++ A +T
Sbjct: 413 EALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKT 460
Score = 38.9 bits (89), Expect = 0.004
Identities = 20/66 (30%), Positives = 39/66 (59%)
Query: 57 DEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLAD 116
D+++ ++K + EK+K+ E+ K + + KK++EE K+ E+ K E++ A+
Sbjct: 340 DQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAE 399
Query: 117 KLRLKK 122
K RLK+
Sbjct: 400 KQRLKE 405
Score = 31.2 bits (69), Expect = 0.93
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
Query: 37 DRWEGEDEDEDVKDNWDDDDD-----EKKEEAEVKPEVKISEKKKIAEKIKEKER---QQ 88
+ WE E+ E + + DDDD E +++ P +SE + + E+ + E +Q
Sbjct: 602 EEWEEEEPGESLSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVRQ 661
Query: 89 KKRQEEIKKRLEEPEEPKVLTP 110
K + +E + L + + +VL P
Sbjct: 662 KLKAKEWDEFLAKGKRFRVLQP 683
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/97 (27%), Positives = 57/97 (58%), Gaps = 2/97 (2%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEV-KISEKKKIAEKIKEKERQQKKRQEEIKKR 98
E + E++++ + + E+++E E + E + E++K E+ +EKE++ +K QE+ ++
Sbjct: 496 EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM 555
Query: 99 LEEPEEPKVLTPEEQLADKLRLKKLQE-ESDLELAKE 134
+E ++ K E Q + L+K++E E + EL KE
Sbjct: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKECELEKE 592
Score = 42.4 bits (98), Expect = 4e-04
Identities = 31/119 (26%), Positives = 62/119 (52%), Gaps = 4/119 (3%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKIS---EKKKIAEKIKEKERQQKKRQEEIK 96
E E E E K+ D + ++++E E++ E + EK++ EK KE ERQ K++++E++
Sbjct: 520 EKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQ-KEKEKELQ 578
Query: 97 KRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDD 155
K E+ +E ++ E+L +K+ ++ E +E + N + S+R +
Sbjct: 579 KMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSE 637
Score = 39.3 bits (90), Expect = 0.003
Identities = 23/91 (25%), Positives = 53/91 (58%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRL 99
E E E E ++ + D E+++E E + E + +++++ ++ K+++ ++ +RQ+E +K L
Sbjct: 518 ELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKEL 577
Query: 100 EEPEEPKVLTPEEQLADKLRLKKLQEESDLE 130
++ +E + E+ +KL K E +LE
Sbjct: 578 QKMKEQEKECELEKEREKLEEKIEPREPNLE 608
Score = 37.4 bits (85), Expect = 0.013
Identities = 26/89 (29%), Positives = 51/89 (57%), Gaps = 3/89 (3%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQ--QKKRQEEIKK 97
E E E E K+ + + E+++E E K + EK+K EK +EK+R+ ++++QE+ K+
Sbjct: 508 EREKEREREKELEKEQEQEREKERE-KDRERQQEKEKELEKEQEKQREMEKERKQEKEKE 566
Query: 98 RLEEPEEPKVLTPEEQLADKLRLKKLQEE 126
+ E+ K L ++ + L+K +E+
Sbjct: 567 LERQKEKEKELQKMKEQEKECELEKEREK 595
Score = 36.6 bits (83), Expect = 0.022
Identities = 24/94 (25%), Positives = 53/94 (56%), Gaps = 3/94 (3%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQ-QKKRQEEIKKRLE 100
E+E+ +++ EK + + K + I EK+ E+I+E+ER+ +++R++E++K E
Sbjct: 467 EEEERRMEEQRKAACAEKLKRLDEK--LGILEKQPSPEEIREREREKEREREKELEKEQE 524
Query: 101 EPEEPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
+ E + E+ +K + + ++E E+ KE
Sbjct: 525 QEREKEREKDRERQQEKEKELEKEQEKQREMEKE 558
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 43.1 bits (100), Expect = 2e-04
Identities = 23/99 (23%), Positives = 59/99 (59%), Gaps = 1/99 (1%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
+ W E++ + + W+++ +++E+ + E KI E+++ + +EK R+Q+++++E +
Sbjct: 545 EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE 604
Query: 97 KRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKET 135
+++ + EE K+ EE++ ++ + QEE E + T
Sbjct: 605 EKMWKQEE-KIREQEEKIQEQEEKIREQEEKIREQEEMT 642
Score = 40.4 bits (93), Expect = 0.002
Identities = 28/110 (25%), Positives = 58/110 (52%), Gaps = 13/110 (11%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEV-KPEVKISEKK-----------KIAEKIKEKER 86
WE E E W ++ +++E +V + E KI E++ K EKI+E+E
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 87 QQKKRQEEIKKRLEEPEEPKVLTPE-EQLADKLRLKKLQEESDLELAKET 135
+ ++++E+I+++ E+ E + +T E E+ + K ++E ++ +ET
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669
Score = 38.1 bits (87), Expect = 0.008
Identities = 25/98 (25%), Positives = 55/98 (56%), Gaps = 3/98 (3%)
Query: 39 WEGEDEDEDVKDNWDDDDDE--KKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
W E++ + ++ + +++ K+EE + E KI E+++ + +EK R+Q++ +E +
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQE 646
Query: 97 KRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
+++ E EE K+ EE++ ++ QEE E K+
Sbjct: 647 EKMGEQEE-KMCEQEEKMQEQEETMWRQEEKIREQEKK 683
Score = 37.7 bits (86), Expect = 0.010
Identities = 24/86 (27%), Positives = 51/86 (59%), Gaps = 4/86 (4%)
Query: 41 GEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLE 100
GE E++ + ++ +++EE + E KI E++K + +EK R+Q++ +E ++++
Sbjct: 650 GEQEEKMCEQ---EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 706
Query: 101 EPEEPKVLTPEEQLADKLRLKKLQEE 126
E EE K+ EE++ ++ + QEE
Sbjct: 707 EQEE-KMCEQEEKMQEQEEKMRRQEE 731
Score = 37.0 bits (84), Expect = 0.017
Identities = 19/86 (22%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKP-EVKISEKKKIAEKIKEKERQQKKRQEEIKKRLE 100
E E + W ++ +++E +++ E KI E++++ ++ +EK +Q+++ E +++++
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 720
Query: 101 EPEEPKVLTPEEQLADKLRLKKLQEE 126
E EE E+ ++RL++ +E+
Sbjct: 721 EQEEKMRRQEEKMWEQEVRLRQQEEK 746
Score = 36.6 bits (83), Expect = 0.022
Identities = 26/96 (27%), Positives = 54/96 (56%), Gaps = 4/96 (4%)
Query: 39 WEGEDEDEDVKDN-WDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKK 97
WE E++ ++ W+ ++ ++ E ++ + KI E+++ ++ +EK R+Q+KRQE+ K
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAK 431
Query: 98 RLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAK 133
+E K+ EE++ ++ + QEE E K
Sbjct: 432 MWR--QEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465
Score = 36.6 bits (83), Expect = 0.022
Identities = 22/110 (20%), Positives = 61/110 (55%), Gaps = 14/110 (12%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAE----------KIKEKERQQ 88
WE E++ ++++ + + +++E + + E KI E++K E KI+E+E +
Sbjct: 387 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
Query: 89 KKRQEEIKKRLEEPEEPKVLTPEEQLADKLRL----KKLQEESDLELAKE 134
+++++++ ++ E+ E + + EE+ ++ + +K+ E+ ++ KE
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
Score = 36.2 bits (82), Expect = 0.029
Identities = 24/100 (24%), Positives = 55/100 (55%), Gaps = 14/100 (14%)
Query: 37 DRWEGEDEDEDVKDNW--------DDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQ 88
+ W E++ + ++ W ++ K+EE + E KI E++ EKI+E+E +
Sbjct: 477 EMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE---EKIREQEEKM 533
Query: 89 KKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESD 128
+++E+I+++ E E + + +E++ ++ +K QE+ D
Sbjct: 534 WRQEEKIREQEEMWREEEKMHEQEKIWEE---EKRQEQED 570
Score = 35.0 bits (79), Expect = 0.065
Identities = 24/95 (25%), Positives = 57/95 (60%), Gaps = 11/95 (11%)
Query: 43 DEDEDVKDNWD--DDDDEKKEEAEVK---PEVKISEKKKIA----EKIKEKERQQKKRQE 93
+++E +++ + + +EK E E K E K+ E+++ EKI+E+E++ ++++E
Sbjct: 630 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEE 689
Query: 94 EIKKRLE--EPEEPKVLTPEEQLADKLRLKKLQEE 126
+I+++ E + +E K+ EE++ ++ + QEE
Sbjct: 690 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 724
Score = 34.7 bits (78), Expect = 0.085
Identities = 19/88 (21%), Positives = 54/88 (61%), Gaps = 6/88 (6%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR 98
W+ E++ + ++ + +++ +E+ E KI E++++ ++ +EK +Q+++ E +++
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEE-----KIREQEEMTQEQEEKMGEQEEKMCEQEEK 662
Query: 99 LEEPEEPKVLTPEEQLADKLRLKKLQEE 126
++E EE + EE++ ++ + + QEE
Sbjct: 663 MQEQEE-TMWRQEEKIREQEKKIREQEE 689
Score = 33.9 bits (76), Expect = 0.14
Identities = 24/90 (26%), Positives = 53/90 (58%), Gaps = 7/90 (7%)
Query: 44 EDEDVKDNWDDDDDEKKEEAEV--KPEVKISEKKKI---AEKIKEKERQQKKRQEEIKKR 98
++E + + ++EK++E E + E KI E+++I EK+ E+E + +K++E++ ++
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
Query: 99 LEE--PEEPKVLTPEEQLADKLRLKKLQEE 126
E+ +E K+ EE++ + + QEE
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEE 545
Score = 33.5 bits (75), Expect = 0.19
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 6/76 (7%)
Query: 57 DEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKR---QEEIKKRLEE---PEEPKVLTP 110
++++EE + E KI E ++ ++ +EK R+Q+++ QEE +R EE +E K+
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 111 EEQLADKLRLKKLQEE 126
EE + +K + QEE
Sbjct: 355 EEMMWEKEEKMRRQEE 370
Score = 32.7 bits (73), Expect = 0.32
Identities = 23/93 (24%), Positives = 51/93 (54%), Gaps = 5/93 (5%)
Query: 39 WEGEDEDEDVKDNWDDDDDE--KKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
W E++ + ++ + +++ ++EE + E E++K+ E+ K E ++++ QE+
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
Query: 97 KRLEE---PEEPKVLTPEEQLADKLRLKKLQEE 126
R EE +E KV EE++ ++ ++ QEE
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605
Score = 32.3 bits (72), Expect = 0.42
Identities = 17/85 (20%), Positives = 51/85 (60%), Gaps = 1/85 (1%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEE 101
E++ ++ ++ W ++ ++E + + K+ E+++ K +EK +Q+++ E ++++ E
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Query: 102 PEEPKVLTPEEQLADKLRLKKLQEE 126
EE K+ EE++ ++ + + +E+
Sbjct: 529 QEE-KMWRQEEKIREQEEMWREEEK 552
Score = 32.0 bits (71), Expect = 0.55
Identities = 19/87 (21%), Positives = 53/87 (60%), Gaps = 7/87 (8%)
Query: 42 EDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEE 101
++++E +++ ++ ++EE + E K+ E++ EK+ E+E + ++++E + ++ E+
Sbjct: 622 QEQEEKIREQ--EEKIREQEEMTQEQEEKMGEQE---EKMCEQEEKMQEQEETMWRQEEK 676
Query: 102 --PEEPKVLTPEEQLADKLRLKKLQEE 126
+E K+ EE++ ++ + + QEE
Sbjct: 677 IREQEKKIREQEEKIREQEEMMQEQEE 703
Score = 31.6 bits (70), Expect = 0.72
Identities = 25/94 (26%), Positives = 49/94 (52%), Gaps = 6/94 (6%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKK---RQEEI 95
W ++ ++ K ++ ++ EE + E KI E+++ + +EK R+Q++ +EE
Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350
Query: 96 KKRLEE---PEEPKVLTPEEQLADKLRLKKLQEE 126
+R EE +E K+ EE + +K + QEE
Sbjct: 351 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
Score = 31.6 bits (70), Expect = 0.72
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 24/111 (21%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKP--------EVKISEKKKIAEKIK--EKE---R 86
E E E W ++ +++E +++ E KI E++KI E+ K E+E R
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
Query: 87 QQKK--RQEEI---KKRLEEPE------EPKVLTPEEQLADKLRLKKLQEE 126
Q++K QEEI K+++ E E E KV EE++ ++ + QEE
Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEE 531
Score = 30.4 bits (67), Expect = 1.6
Identities = 20/91 (21%), Positives = 53/91 (58%), Gaps = 6/91 (6%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR 98
WE + ++++ K ++ ++EE + E + EK+ EK++ +E +++E+++++
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE---EKMRRQEEMMWEKEEKMRRQ 368
Query: 99 LEE--PEEPKVLTPEEQLADK-LRLKKLQEE 126
E +E K+ EE + +K ++++L+E+
Sbjct: 369 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 399
Score = 29.3 bits (64), Expect = 3.6
Identities = 14/76 (18%), Positives = 45/76 (59%)
Query: 59 KKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKL 118
+KEE + E + EK++ + +E +++++ E+++++ E E+ + + Q +K+
Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419
Query: 119 RLKKLQEESDLELAKE 134
R ++ ++E + ++ ++
Sbjct: 420 REQEKRQEQEAKMWRQ 435
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 43.1 bits (100), Expect = 2e-04
Identities = 36/191 (18%), Positives = 98/191 (51%), Gaps = 8/191 (4%)
Query: 39 WEGEDEDEDVKDN-WDDDDD-EKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
WE E++ D + WD ++ EKK + + K EK + E+++E+E++ ++ +E ++
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 606
Query: 97 KRLE--EPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRD 154
++ E + +E K+ EE++ ++ + QEE E ++ + ++ + P ++
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL-PEQKE 665
Query: 155 DFTEFGKLL-KDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQ 213
E K+ ++K+ + E+ ++ +E ++ + D +K+ ++ EK+ +
Sbjct: 666 KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ--EKKTWDQEKMREEESMREREKKMR 723
Query: 214 EKQSKAKKKKK 224
E++ +++++
Sbjct: 724 EEEEMMREQEE 734
Score = 39.7 bits (91), Expect = 0.003
Identities = 31/143 (21%), Positives = 71/143 (49%), Gaps = 8/143 (5%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKER----QQKKRQEE 94
WE + E + W+ + +++E+ + + E KI E++K+ +K +E+E+ Q+K R+EE
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEE-KIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Query: 95 IKKRLEEP--EEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSS 152
+ E+ EE +++ +E+ + K ++E ++ +E P
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 153 RDDFTEFGKLL-KDKITQYEKSL 174
++ E K+ ++KI + E+ +
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEEKM 796
Score = 38.9 bits (89), Expect = 0.004
Identities = 25/110 (22%), Positives = 58/110 (52%), Gaps = 15/110 (13%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKI----------AEKIKEKERQQ 88
WE E E + W+ ++ + +E E K+ ++K+ EK++++E++
Sbjct: 501 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 560
Query: 89 KKRQEEIKKRLEEPEEPKVLTPEEQLADKLRL----KKLQEESDLELAKE 134
++E ++K+ +E +E K EE++ ++ R+ KK++EE ++ +E
Sbjct: 561 WDQEERMEKKTQE-QEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609
Score = 38.5 bits (88), Expect = 0.006
Identities = 26/101 (25%), Positives = 57/101 (56%), Gaps = 12/101 (11%)
Query: 39 WEGE----DEDEDVKDN----WDDDDDEKKEEAEVKPEVKISEK-KKIAEKIKEKERQQK 89
WE E ++++ ++D W+ D+ +++E ++ + K+ E+ +K+ E+ K +E+++K
Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438
Query: 90 KRQEEIKKRLEE---PEEPKVLTPEEQLADKLRLKKLQEES 127
R +E K + EE E K+ EE + ++ + QEE+
Sbjct: 439 TRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Score = 34.7 bits (78), Expect = 0.085
Identities = 22/88 (25%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEVKPEVK-ISEKKKIAEKIKEKERQQKKRQEEIKKR 98
EG+ +++ K W + +++E E++ + K + E+K++ E+ ++ + Q++K E+ +K
Sbjct: 306 EGKMREQEEK-MWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKM 364
Query: 99 LEEPEEPKVLTPEEQLADKLRLKKLQEE 126
E +E K+ EE+L ++ + + QE+
Sbjct: 365 RE--QEEKMWRQEERLWEQEKQMREQEQ 390
Score = 33.9 bits (76), Expect = 0.14
Identities = 22/92 (23%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEI--- 95
W E E W+ ++ + +E ++ + + EKK ++ K ++++K R+EE
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRE 593
Query: 96 -KKRLEEPEEPKVLTPEEQLADKLRLKKLQEE 126
+K++ E EE + EE++ ++ + QEE
Sbjct: 594 REKKMRE-EEEMMREQEEKMQEQEEKMQEQEE 624
Score = 33.5 bits (75), Expect = 0.19
Identities = 23/97 (23%), Positives = 55/97 (56%), Gaps = 12/97 (12%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR 98
WE ++ + K + + + +E +++ E +I E++K K++E+E ++++E+++K+
Sbjct: 420 WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREK---KMREEEETMREQEEKMQKQ 476
Query: 99 ------LEEPEEPKVLTPEEQLADKL-RLKKLQEESD 128
EE E + PE++ +KL +K+QE+ +
Sbjct: 477 EENMWEQEEKEWQQQRLPEQK--EKLWEQEKMQEQEE 511
Score = 32.7 bits (73), Expect = 0.32
Identities = 21/100 (21%), Positives = 55/100 (55%), Gaps = 5/100 (5%)
Query: 37 DRWEGEDE--DEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEE 94
+ W E+E +++ K ++ ++EE + E K+ E++ EK+ +E++ +++++E
Sbjct: 273 EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE---EKMWRQEKRLREQEKE 329
Query: 95 IKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
++++ +E E K L +E+ + K ++E + +E
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE 369
Score = 32.7 bits (73), Expect = 0.32
Identities = 30/123 (24%), Positives = 60/123 (48%), Gaps = 20/123 (16%)
Query: 10 DSDSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEV 69
+ +WD + E+ +R +R + E+E++ + +EK +E E K +
Sbjct: 700 EKKTWDQEKMREEESMR----------EREKKMREEEEMMR----EQEEKMQEQEEKMQE 745
Query: 70 KISEKKKIAEKIKEKERQ--QKKRQEEIKKRLEE----PEEPKVLTPEEQLADKLRLKKL 123
+ E + EK+ E+E + +++R E K++L E E+ K+ EE++ D+ +
Sbjct: 746 QEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRG 805
Query: 124 QEE 126
QEE
Sbjct: 806 QEE 808
Score = 32.3 bits (72), Expect = 0.42
Identities = 19/111 (17%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 39 WEGEDEDEDVKDNW---------------DDDDDEKKEEAEVKPEVKISEKKKIAEKIKE 83
WE E++ D ++ W +D E++E+ + + +++++ +K +E
Sbjct: 514 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQE 573
Query: 84 KERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
+E++ ++E++++ E K + EE++ + K ++E ++ +E
Sbjct: 574 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624
Score = 32.0 bits (71), Expect = 0.55
Identities = 24/89 (26%), Positives = 53/89 (59%), Gaps = 8/89 (8%)
Query: 43 DEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEP 102
+E+E +++ ++ +K+EE + E K +++++ E+ KEK +Q+K QE+ +K E
Sbjct: 461 EEEETMREQ--EEKMQKQEENMWEQEEKEWQQQRLPEQ-KEKLWEQEKMQEQEEKIWE-- 515
Query: 103 EEPKVLTPEEQLADKLRL---KKLQEESD 128
+E K+ EE + ++ +K++E+ D
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQED 544
Score = 31.6 bits (70), Expect = 0.72
Identities = 28/110 (25%), Positives = 53/110 (48%), Gaps = 10/110 (9%)
Query: 42 EDEDEDVKDNWDDDD-----DEKKEEAEVKPE--VKISEKKKIAEKIKEKERQQKKRQEE 94
E E ++ W+ ++ +EK E + PE K+ E +K+ E+ K E+++K R +E
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQE 800
Query: 95 IKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYG 144
K R +E K+ EE++ + QEE ++ +G ++G
Sbjct: 801 EKMR---GQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWG 847
Score = 30.8 bits (68), Expect = 1.2
Identities = 22/102 (21%), Positives = 57/102 (55%), Gaps = 7/102 (6%)
Query: 39 WEGEDEDEDVKDN-WDDDD---DEKKEEAEVKPEVKISEKK--KIAEKIKEKERQQKKRQ 92
WE E++ + ++ W ++ +++K+ E + +++ E++ + E+++EKE + ++ Q
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE-Q 416
Query: 93 EEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKE 134
E++ +++E+ E K + +E+ K +EE E K+
Sbjct: 417 EKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKK 458
Score = 29.3 bits (64), Expect = 3.6
Identities = 24/106 (22%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 39 WEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKK-RQEEIKK 97
WE E++ D ++ +++ + + E +++ E+K ++ K +++K QEE
Sbjct: 790 WEQEEKMRDQEEKMRGQEEKMRGQEE---KMRGQEEKMWGQEEKMWGQEEKMWGQEEKMW 846
Query: 98 RLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVY 143
EE E K+ EE++ ++ + QEE E ++ G +Y
Sbjct: 847 GQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIY 892
Score = 28.9 bits (63), Expect = 4.6
Identities = 19/88 (21%), Positives = 52/88 (59%), Gaps = 2/88 (2%)
Query: 40 EGEDEDEDVKDNWDDDDDEKKEEAEV-KPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR 98
E E E + K+ + ++ +++E ++ + E K+ E+++ + +E+ +Q+K+ E +++
Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 391
Query: 99 LEEPEEPKVLTPEEQLADKLRLKKLQEE 126
+ + EE ++ +E+L +K + QE+
Sbjct: 392 MRDQEE-RMWEQDERLREKEERMREQEK 418
>gi|82830424 gon-4-like isoform a [Homo sapiens]
Length = 2240
Score = 43.1 bits (100), Expect = 2e-04
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 9/115 (7%)
Query: 12 DSWDADAFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVK- 70
DS D SV PV GG G + E ED D+ +D D+ +E PE++
Sbjct: 1433 DSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQE 1492
Query: 71 --------ISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADK 117
SE++ E E+E Q++ E ++ EE E + L E+++ D+
Sbjct: 1493 TMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDE 1547
>gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo
sapiens]
Length = 373
Score = 42.7 bits (99), Expect = 3e-04
Identities = 30/99 (30%), Positives = 52/99 (52%), Gaps = 2/99 (2%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
D +GEDE EDV D D D+D EA+V + + + +++ + Q++++Q +
Sbjct: 80 DDGDGEDE-EDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLP 138
Query: 97 KRLEEPEEPKVLTPEEQLADKLRLKKLQE-ESDLELAKE 134
+ P E + E++ D+L+LK L+E LE KE
Sbjct: 139 ESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKE 177
Score = 36.2 bits (82), Expect = 0.029
Identities = 22/71 (30%), Positives = 42/71 (59%), Gaps = 4/71 (5%)
Query: 57 DEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLAD 116
+E ++ E + E++ EK+KI + K KE QKK +++ K+R ++ + EE+ A
Sbjct: 166 EELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEM----EEKAAK 221
Query: 117 KLRLKKLQEES 127
+L + LQE++
Sbjct: 222 ELEKEYLQEKA 232
Score = 35.4 bits (80), Expect = 0.050
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 45 DEDVKDNWDDDDDEKKEEAEVK-------PEVKISEKKKIAEKIKEKERQ--QKKRQEEI 95
+E K+ +++K++E E K K EK+ + EK KEK ++ +KK EE
Sbjct: 189 EEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEEC 248
Query: 96 KKRLEEPEEPKVLTPEEQLADKLRLKKLQE 125
+++ +E E+ K E Q ++ KK QE
Sbjct: 249 ERKKKEKEKEKQQQAEIQEKKEIAEKKFQE 278
Score = 29.6 bits (65), Expect = 2.7
Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 11/129 (8%)
Query: 58 EKKEEAEVKPEVKISEKKKIAEKI------KEKERQQKKRQEEIKKRLEEPEEPKVLTPE 111
EK++E E + + KI ++K E + K KER+QK +E +K +E E+ + +
Sbjct: 173 EKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYL---Q 229
Query: 112 EQLADKLR--LKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQ 169
E+ +K + LKK E KE I + F E+ + K K
Sbjct: 230 EKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRP 289
Query: 170 YEKSLYYAS 178
KS YA+
Sbjct: 290 AAKSYGYAN 298
Score = 28.9 bits (63), Expect = 4.6
Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Query: 40 EGEDEDEDVKDNWDDDDDEKK-EEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKR 98
E E E K+ + + +K EE E K + K EK++ AE ++KE +KK QE ++
Sbjct: 224 EKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENA 283
Query: 99 LEEP 102
+P
Sbjct: 284 KHKP 287
>gi|18087817 coiled-coil domain containing 34 isoform 2 [Homo
sapiens]
Length = 229
Score = 42.7 bits (99), Expect = 3e-04
Identities = 30/99 (30%), Positives = 52/99 (52%), Gaps = 2/99 (2%)
Query: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
D +GEDE EDV D D D+D EA+V + + + +++ + Q++++Q +
Sbjct: 80 DDGDGEDE-EDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLP 138
Query: 97 KRLEEPEEPKVLTPEEQLADKLRLKKLQE-ESDLELAKE 134
+ P E + E++ D+L+LK L+E LE KE
Sbjct: 139 ESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKE 177
Score = 28.1 bits (61), Expect = 7.9
Identities = 13/37 (35%), Positives = 23/37 (62%)
Query: 57 DEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQE 93
+E ++ E + E++ EK+KI + K KE QKK ++
Sbjct: 166 EELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQ 202
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 42.7 bits (99), Expect = 3e-04
Identities = 39/126 (30%), Positives = 63/126 (50%), Gaps = 11/126 (8%)
Query: 1 MAAAAAAAGDSDSWDADAFSVEDPVRKVGGGG---TAGGDRWEGE--DEDEDVKDNWDDD 55
+AA+ A D DS D F V D G G A D EG D +E++ + ++
Sbjct: 13 LAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNE 72
Query: 56 DDEKKEEA---EVKPEVKISEKKKIAEKIKEKE---RQQKKRQEEIKKRLEEPEEPKVLT 109
D + KEE + EV SEK+ I + KE+E + +K++E+ K++ +E E+ K
Sbjct: 73 DIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKERE 132
Query: 110 PEEQLA 115
E++ A
Sbjct: 133 KEKEKA 138
>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
Length = 948
Score = 42.7 bits (99), Expect = 3e-04
Identities = 39/126 (30%), Positives = 63/126 (50%), Gaps = 11/126 (8%)
Query: 1 MAAAAAAAGDSDSWDADAFSVEDPVRKVGGGG---TAGGDRWEGE--DEDEDVKDNWDDD 55
+AA+ A D DS D F V D G G A D EG D +E++ + ++
Sbjct: 13 LAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNE 72
Query: 56 DDEKKEEA---EVKPEVKISEKKKIAEKIKEKE---RQQKKRQEEIKKRLEEPEEPKVLT 109
D + KEE + EV SEK+ I + KE+E + +K++E+ K++ +E E+ K
Sbjct: 73 DIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKERE 132
Query: 110 PEEQLA 115
E++ A
Sbjct: 133 KEKEKA 138
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.130 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,647,571
Number of Sequences: 37866
Number of extensions: 560226
Number of successful extensions: 15763
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 625
Number of HSP's successfully gapped in prelim test: 715
Number of HSP's that attempted gapping in prelim test: 5532
Number of HSP's gapped (non-prelim): 6359
length of query: 258
length of database: 18,247,518
effective HSP length: 100
effective length of query: 158
effective length of database: 14,460,918
effective search space: 2284825044
effective search space used: 2284825044
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.