Search of human proteins with 7710143

Search of human proteins with 7710143

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo
sapiens]
         (503 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo s...  1064   0.0  
gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo...  1042   0.0  
gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ...  1004   0.0  
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ...   973   0.0  
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho...   873   0.0  
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i...    86   1e-16
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s...    86   1e-16
gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens]          74   3e-13
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    57   5e-08
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    54   3e-07
gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]     54   4e-07
gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]       54   4e-07
gi|27735129 hypothetical protein LOC148345 [Homo sapiens]              47   5e-05
gi|17136078 VGF nerve growth factor inducible precursor [Homo sa...    47   5e-05
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]       46   7e-05
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]       46   7e-05
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi...    46   7e-05
gi|13699803 WAS protein family, member 3 [Homo sapiens]                46   9e-05
gi|7019335 hypothetical protein LOC745 isoform 1 [Homo sapiens]        45   1e-04
gi|188528652 hypothetical protein LOC745 isoform 2 [Homo sapiens]      45   1e-04
gi|41352718 deltex homolog 1 [Homo sapiens]                            45   2e-04
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         44   3e-04
gi|153792074 proline rich 12 [Homo sapiens]                            44   3e-04
gi|47132519 Ras association and pleckstrin homology domains 1 is...    44   4e-04
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    44   4e-04
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]             43   6e-04
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]              43   6e-04
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    43   6e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    43   8e-04
gi|150170670 piccolo isoform 2 [Homo sapiens]                          43   8e-04

>gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo
           sapiens]
          Length = 503

 Score = 1064 bits (2752), Expect = 0.0
 Identities = 503/503 (100%), Positives = 503/503 (100%)

Query: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
           MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60

Query: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
           LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120

Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
           DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180

Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
           ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240

Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
           PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300

Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHH 360
           TEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHH
Sbjct: 301 TEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHH 360

Query: 361 LGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAAS 420
           LGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAAS
Sbjct: 361 LGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAAS 420

Query: 421 TEALLQAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGT 480
           TEALLQAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGT
Sbjct: 421 TEALLQAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGT 480

Query: 481 RFRDTAVWLPRSKDLKKPGARKQ 503
           RFRDTAVWLPRSKDLKKPGARKQ
Sbjct: 481 RFRDTAVWLPRSKDLKKPGARKQ 503


>gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo
           sapiens]
          Length = 549

 Score = 1042 bits (2695), Expect = 0.0
 Identities = 503/549 (91%), Positives = 503/549 (91%), Gaps = 46/549 (8%)

Query: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
           MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60

Query: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
           LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120

Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
           DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180

Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
           ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240

Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
           PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300

Query: 301 TEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHH 360
           TEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHH
Sbjct: 301 TEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHH 360

Query: 361 LGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAAS 420
           LGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAAS
Sbjct: 361 LGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAAS 420

Query: 421 TEALLQ----------------------------------------------AVDPGLPS 434
           TEALLQ                                              AVDPGLPS
Sbjct: 421 TEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPS 480

Query: 435 VKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKD 494
           VKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKD
Sbjct: 481 VKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKD 540

Query: 495 LKKPGARKQ 503
           LKKPGARKQ
Sbjct: 541 LKKPGARKQ 549


>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
           sapiens]
          Length = 605

 Score = 1004 bits (2595), Expect = 0.0
 Identities = 498/605 (82%), Positives = 501/605 (82%), Gaps = 102/605 (16%)

Query: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
           MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60

Query: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
           LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120

Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
           DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180

Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
           ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240

Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
           PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300

Query: 301 TEPHPRALAPSPPAEFIYY------------------------------------CVDED 324
           TEPHPRALAPSPPAEFIYY                                    C D+ 
Sbjct: 301 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 360

Query: 325 E--------------------LKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 364
           +                    +KRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT
Sbjct: 361 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 420

Query: 365 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 424
           LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL
Sbjct: 421 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 480

Query: 425 LQ----------------------------------------------AVDPGLPSVKQE 438
           LQ                                              AVDPGLPSVKQE
Sbjct: 481 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 540

Query: 439 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 498
           PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP
Sbjct: 541 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 600

Query: 499 GARKQ 503
           GARKQ
Sbjct: 601 GARKQ 605


>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
           sapiens]
          Length = 586

 Score =  973 bits (2515), Expect = 0.0
 Identities = 471/523 (90%), Positives = 475/523 (90%), Gaps = 33/523 (6%)

Query: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
           MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60

Query: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
           LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120

Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
           DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180

Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
           ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC
Sbjct: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240

Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
           PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300

Query: 301 TEPHP-------------RALAPSPPAEFIYYCVDEDE--------------------LK 327
           TEP P              A           +C D+ +                    +K
Sbjct: 301 TEPQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK 360

Query: 328 RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA 387
           RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA
Sbjct: 361 RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEA 420

Query: 388 GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDKE 447
           GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDKE
Sbjct: 421 GGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDKE 480

Query: 448 ENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 490
           ENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP
Sbjct: 481 ENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLP 523


>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
           sapiens]
          Length = 556

 Score =  873 bits (2255), Expect = 0.0
 Identities = 448/605 (74%), Positives = 452/605 (74%), Gaps = 151/605 (24%)

Query: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60
           MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT
Sbjct: 1   MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLT 60

Query: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120
           LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT
Sbjct: 61  LFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADT 120

Query: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECA 180
           DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMF         
Sbjct: 121 DTAPASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMF--------- 171

Query: 181 ACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHC 240
                                                   +SRGCGVCRGCQTQEDCGHC
Sbjct: 172 ----------------------------------------KSRGCGVCRGCQTQEDCGHC 191

Query: 241 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
           PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP
Sbjct: 192 PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 251

Query: 301 TEPHPRALAPSPPAEFIYY------------------------------------CVDED 324
           TEPHPRALAPSPPAEFIYY                                    C D+ 
Sbjct: 252 TEPHPRALAPSPPAEFIYYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKP 311

Query: 325 E--------------------LKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 364
           +                    +KRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT
Sbjct: 312 KFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPT 371

Query: 365 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 424
           LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL
Sbjct: 372 LKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEAL 431

Query: 425 LQ----------------------------------------------AVDPGLPSVKQE 438
           LQ                                              AVDPGLPSVKQE
Sbjct: 432 LQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQE 491

Query: 439 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 498
           PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP
Sbjct: 492 PPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKP 551

Query: 499 GARKQ 503
           GARKQ
Sbjct: 552 GARKQ 556


>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
           isoform [Homo sapiens]
          Length = 302

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)

Query: 6   LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65
           +DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG   DL+ FDF+
Sbjct: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209

Query: 66  QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97
            G       K  P  +   K++  + P    K
Sbjct: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234


>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
           sapiens]
          Length = 411

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)

Query: 6   LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65
           +DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG   DL+ FDF+
Sbjct: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209

Query: 66  QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97
            G       K  P  +   K++  + P    K
Sbjct: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234


>gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens]
          Length = 291

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 32/61 (52%), Positives = 43/61 (70%)

Query: 7  DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQ 66
          +CPAL  GW+R EV R+SG + G  D +Y SP+G + RSK +L RYLG + DL+ FDF+ 
Sbjct: 7  ECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYLGGSMDLSTFDFRT 66

Query: 67 G 67
          G
Sbjct: 67 G 67


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 64/262 (24%), Positives = 97/262 (37%), Gaps = 60/262 (22%)

Query: 221  RSRGCGVCRGCQTQEDCGHCPICLRPPRPG-------------------------LRRQW 255
            RSR CG C GCQ  EDCG C  CL  P+ G                         L++Q 
Sbjct: 1151 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1210

Query: 256  KCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAE 315
            K V+++  + K + +K   DSK ++  +        P PS   +P    P+  +  PP  
Sbjct: 1211 KAVKKKEKKSKTSEKK---DSKESSVVKNVVDSSQKPTPSAREDPA---PKKSSSEPPPR 1264

Query: 316  FIYYCVDEDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQ 375
                             V  +SE+G  S P    ++  + A R       +P L      
Sbjct: 1265 ---------------KPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQP 1309

Query: 376  PDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSV 435
            P  T  P ++E        P         +    P    GP  +  + +  A  P +P V
Sbjct: 1310 P--TTGPPRKEVPKTTPSEP---------KKKQPPPPESGPEQSKQKKV--APRPSIP-V 1355

Query: 436  KQEPPDPEEDKEENKDDSASKL 457
            KQ+P + E+    NK ++A  L
Sbjct: 1356 KQKPKEKEKPPPVNKQENAGTL 1377


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
            sapiens]
          Length = 2715

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 52/176 (29%), Positives = 76/176 (43%), Gaps = 30/176 (17%)

Query: 221  RSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRCLRGKHARRKGGCDSK 277
            R   CG CRGC   +DCG C  CL  P+   P  ++Q  CV R+C   K   RK     +
Sbjct: 962  RMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQC-CVYRKC--DKIEARK---MER 1015

Query: 278  MAARRRPGAQPLPPPPPSQSPE--PTEPHPR--ALAPSPPAEFIYYCVDEDE-------- 325
            +A + R   + L P    +SPE  P  P PR  A A  P  E + +   E++        
Sbjct: 1016 LAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKS 1075

Query: 326  -----LKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQP 376
                  +R    ++ +S+D     PP  RR+ P    R +  P  +P   +R  +P
Sbjct: 1076 ARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTP----RENELPLPEPEEQSRPRKP 1127



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 49/186 (26%), Positives = 59/186 (31%), Gaps = 39/186 (20%)

Query: 284 PGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGS 343
           P   P P PPP   P  T P P    P PP       V    L    P    E ++   S
Sbjct: 405 PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPP------VSPPPLPSPPPPPAQEEQE--ES 456

Query: 344 PPPY------RRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQ--APTKQEAGGG----- 390
           PPP       R+R RP       L P+ +       A P+ T    PT   A GG     
Sbjct: 457 PPPVVPATCSRKRGRPP------LTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDS 510

Query: 391 -FVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPG-----------LPSVKQE 438
             V P   T L  +R+     V         T       DP             P +   
Sbjct: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTS 570

Query: 439 PPDPEE 444
           PP P+E
Sbjct: 571 PPVPQE 576



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 37/177 (20%)

Query: 281 RRRPGAQPLPPPPPSQSPEP---TEPHPRALAPSPPAEFIYYCVDEDELK----RLLPSV 333
           R  P   P PPPPP+ SP P   T      L  +P      +   E  LK     L P  
Sbjct: 616 RELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAP-----QFTPSEAHLKIYESVLTPPP 670

Query: 334 WSESEDGAGSPPPY----RRRKRPSSARRHHLG-PTLKPTLATRTAQPDHTQAPTKQEAG 388
               E     PPP        +  +  R +HL  P   P + T          P K E  
Sbjct: 671 LGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTT----------PVKAE-- 718

Query: 389 GGFVLPPPGTDLVFLREGASSPVQVPGPV-AASTEALLQAVDPGLPSVKQEPPDPEE 444
               + P G     L  G  +  Q+  P+ A  T+ L QA+ P  P + Q PP P++
Sbjct: 719 ----VSPHGAPA--LSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQL-QPPPSPQQ 768



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 46/174 (26%), Positives = 56/174 (32%), Gaps = 10/174 (5%)

Query: 277  KMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFI-YYCVDEDELKRLLPSVWS 335
            KMA    P   P+  PP   +  PT P    L P P    +    V         P +  
Sbjct: 2203 KMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTL 2262

Query: 336  ESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAG---GGF- 391
                G  SPP    R +  S       P   P  A R  +       T Q  G   GGF 
Sbjct: 2263 VLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFS 2322

Query: 392  ----VLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPD 441
                  P     L   R G  +  + PGP+      LL   + G P V   PPD
Sbjct: 2323 RVRMKTPTVRGVLDLDRPGEPAGEESPGPL-QERSPLLPLPEDGPPQVPDGPPD 2375



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 10/20 (50%), Positives = 12/20 (60%)

Query: 176 CGECAACQVTEDCGACSTCL 195
           CG C  C   +DCG+C  CL
Sbjct: 966 CGHCRGCLRVQDCGSCVNCL 985


>gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]
          Length = 498

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)

Query: 7   DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
           D P L  GW R+   RKSG + G+ D Y  +P G   RSKVEL  Y     D +L    F
Sbjct: 108 DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 167

Query: 63  DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
           DF       P+ +        KK K P  P   R R     SG  R +A   E
Sbjct: 168 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 217


>gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]
          Length = 486

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 40/113 (35%), Positives = 48/113 (42%), Gaps = 7/113 (6%)

Query: 7   DCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTL----F 62
           D P L  GW R+   RKSG + G+ D Y  +P G   RSKVEL  Y     D +L    F
Sbjct: 96  DDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDF 155

Query: 63  DFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDE 115
           DF       P+ +        KK K P  P   R R     SG  R +A   E
Sbjct: 156 DFTVTGRGSPSRREQK---PPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSE 205


>gi|27735129 hypothetical protein LOC148345 [Homo sapiens]
          Length = 656

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 64/253 (25%), Positives = 88/253 (34%), Gaps = 29/253 (11%)

Query: 266 KHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDE 325
           K ARR  G  S     R   AQ  P PPP ++  P  P P A  PS P E +        
Sbjct: 274 KPARR--GQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQ--ASPWR 329

Query: 326 LKRLLPS----VWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQA 381
            + +LP+        S D +   PP  R +RP S        TL   L T   + D  ++
Sbjct: 330 PRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKS 389

Query: 382 P-----TKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSV- 435
           P      +  + G    P P             P+  P     + E L+    PG P   
Sbjct: 390 PGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQET 449

Query: 436 ----------KQEPPDPEEDKEENKDDSASKLAPEEEAGGAG---TPVITEIFSLGGTRF 482
                     +  P  P E    + D S+S+  P ++  G G    P     FS    R 
Sbjct: 450 CSGTEVERPRQTGPGLPREGARGHMDLSSSE--PSQDIEGPGLSILPARDATFSTPSVRQ 507

Query: 483 RDTAVWLPRSKDL 495
            D + WL    +L
Sbjct: 508 PDPSAWLSSGPEL 520


>gi|17136078 VGF nerve growth factor inducible precursor [Homo
           sapiens]
          Length = 615

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 40/120 (33%), Positives = 49/120 (40%), Gaps = 21/120 (17%)

Query: 281 RRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDEL---KRLLPSVWSES 337
           +R+  A P P PPP  +P PT  H R+  P PPA         DEL     +LP  W   
Sbjct: 481 KRKKNAPPEPVPPPRAAPAPT--HVRSPQPPPPAP----APARDELPDWNEVLPP-WDRE 533

Query: 338 EDGAGSPPPY---------RRRKRPSSARRHHLGPTLKPT--LATRTAQPDHTQAPTKQE 386
           ED    P PY         R  + PS+ RR H    L P+     R AQ    Q   + E
Sbjct: 534 EDEVYPPGPYHPFPNYIRPRTLQPPSALRRRHYHHALPPSRHYPGREAQARRAQEEAEAE 593


>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
          Length = 660

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 5/90 (5%)

Query: 217 RIVERSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRC-LRGKHARRKG 272
           +I   +R CG C  C+  EDCGHC  C    +   P   RQ KC  R+C LR + + +  
Sbjct: 161 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQ-KCRLRQCQLRARESYKYF 219

Query: 273 GCDSKMAARRRPGAQPLPPPPPSQSPEPTE 302
                         +P  P P  Q P+P++
Sbjct: 220 PSSLSPVTPSESLPRPRRPLPTQQQPQPSQ 249



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)

Query: 166 REQRMFKRVG--CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
           ++Q+  KR    CGEC AC+ TEDCG C  C         + +  KC  R+C
Sbjct: 157 QQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208


>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
          Length = 656

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 5/90 (5%)

Query: 217 RIVERSRGCGVCRGCQTQEDCGHCPICLRPPR---PGLRRQWKCVQRRC-LRGKHARRKG 272
           +I   +R CG C  C+  EDCGHC  C    +   P   RQ KC  R+C LR + + +  
Sbjct: 161 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQ-KCRLRQCQLRARESYKYF 219

Query: 273 GCDSKMAARRRPGAQPLPPPPPSQSPEPTE 302
                         +P  P P  Q P+P++
Sbjct: 220 PSSLSPVTPSESLPRPRRPLPTQQQPQPSQ 249



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)

Query: 166 REQRMFKRVG--CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
           ++Q+  KR    CGEC AC+ TEDCG C  C         + +  KC  R+C
Sbjct: 157 QQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC 208


>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
           sapiens]
          Length = 694

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 89/378 (23%), Positives = 120/378 (31%), Gaps = 110/378 (29%)

Query: 139 SFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECAACQVTEDCGACS----TC 194
           S  G G   +R +T C+ CRA             R  CG+C  C+  +  G       +C
Sbjct: 24  SSRGPGAGARRRRTRCRRCRA-----------CVRTECGDCHFCRDMKKFGGPGRMKQSC 72

Query: 195 LLQ------LPHDVASGLFCKCERRRCLRIVERSRG-----CGVCR-----GCQTQ---- 234
           LL+      LPH     L  +  +   +   E   G     C +C      GC       
Sbjct: 73  LLRQCTAPVLPHTAVCLLCGEAGKEDTVEGEEEKFGLSLMECTICNEIVHPGCLKMGKAE 132

Query: 235 -------EDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQ 287
                   +C  CP C +  R          +RR   G+     G   S       P   
Sbjct: 133 GVINAEIPNCWECPRCTQEGRTSKDSGEGPGRRRADNGEEGASLG---SGWKLTEEP--- 186

Query: 288 PLPPPPP-SQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSPPP 346
           PLPPPPP  + P P  P P  + P PP                        E  AG+ PP
Sbjct: 187 PLPPPPPRRKGPLPAGPPPEDV-PGPP---------------------KRKEREAGNEPP 224

Query: 347 YRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPP----PGTDLVF 402
              RK+    R  HL          R + P           GG  +LPP    P      
Sbjct: 225 -TPRKKVKGGRERHLKKVGGDACLLRGSDP-----------GGPGLLPPRVLNPSQAFSS 272

Query: 403 LREG-ASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDK-----------EENK 450
              G      + P P  AS E       P +PS     P P+ +K           E   
Sbjct: 273 CHPGLPPENWEKPKPPLASAEG------PAVPS-----PSPQREKLERFKRMCQLLERVP 321

Query: 451 DDSASKLAPEEEAGGAGT 468
           D S+S    + ++  +GT
Sbjct: 322 DTSSSSSDSDSDSDSSGT 339


>gi|13699803 WAS protein family, member 3 [Homo sapiens]
          Length = 502

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 48/180 (26%), Positives = 71/180 (39%), Gaps = 30/180 (16%)

Query: 266 KHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDE 325
           +H  R     ++  A  RP  Q  PPPPP Q+PE ++    A AP  PA++         
Sbjct: 283 EHEYRPPSASARHMALNRP--QQPPPPPPPQAPEGSQ----ASAPMAPADY--------- 327

Query: 326 LKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQ 385
              +LP+   E  + +G PPP      P SA+   + P   P      A    T A    
Sbjct: 328 --GMLPAQIIEYYNPSGPPPPPPPPVIP-SAQTAFVSPLQMPMQPPFPASASSTHAAPPH 384

Query: 386 EAGGGFVL---PPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDP 442
               G ++   PPPG            P   PGP ++ + + +    P   + +QEP  P
Sbjct: 385 PPSTGLLVTAPPPPGP--------PPPPPGPPGPGSSLSSSPMHG-PPVAEAKRQEPAQP 435


>gi|7019335 hypothetical protein LOC745 isoform 1 [Homo sapiens]
          Length = 1111

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 50/179 (27%), Positives = 71/179 (39%), Gaps = 32/179 (17%)

Query: 284 PGAQPLPPPPPS---------QSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVW 334
           PG  P PPPPP             EP  PH  A+        +++      L +LL    
Sbjct: 177 PGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLL---- 232

Query: 335 SESEDGAGSPP-PYRRRKR----PSSARRHHLGPTLKPTLATRTAQPDH-TQAPTKQEAG 388
              + GA  P  P ++RK     PS+     L   +K    T TA P H T+AP+     
Sbjct: 233 --QQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPP 290

Query: 389 GGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQ--------AVDPGLPSVKQEP 439
            G + P PG+  + +    + P   PG   A +  LLQ         +DP   S+K +P
Sbjct: 291 QGPLSPGPGSLPLSIARVQTPPWHPPG---APSPGLLQDSDSLSGSYLDPNYQSIKWQP 346


>gi|188528652 hypothetical protein LOC745 isoform 2 [Homo sapiens]
          Length = 1151

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 50/179 (27%), Positives = 71/179 (39%), Gaps = 32/179 (17%)

Query: 284 PGAQPLPPPPPS---------QSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVW 334
           PG  P PPPPP             EP  PH  A+        +++      L +LL    
Sbjct: 186 PGPPPPPPPPPHYPVLQRDLYMKAEPPIPHYAAMGQGLVPTDLHHTQQSQMLHQLL---- 241

Query: 335 SESEDGAGSPP-PYRRRKR----PSSARRHHLGPTLKPTLATRTAQPDH-TQAPTKQEAG 388
              + GA  P  P ++RK     PS+     L   +K    T TA P H T+AP+     
Sbjct: 242 --QQHGAELPTHPSKKRKHSESPPSTLNAQMLNGMIKQEPGTVTALPLHPTRAPSPPWPP 299

Query: 389 GGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQ--------AVDPGLPSVKQEP 439
            G + P PG+  + +    + P   PG   A +  LLQ         +DP   S+K +P
Sbjct: 300 QGPLSPGPGSLPLSIARVQTPPWHPPG---APSPGLLQDSDSLSGSYLDPNYQSIKWQP 355


>gi|41352718 deltex homolog 1 [Homo sapiens]
          Length = 620

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 56/217 (25%), Positives = 77/217 (35%), Gaps = 43/217 (19%)

Query: 257 CVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEF 316
           C  ++CL     R           R+ P A PLPPPPP   P      P ALA  P A F
Sbjct: 200 CSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGGP------PGALAVRPSATF 253

Query: 317 IYYCVDEDELKRLLPSVWSESEDGAGSP-----PPYRRRKRPSSARR------HHLGPTL 365
                          ++W+    G   P      P R    P  AR       +  GP  
Sbjct: 254 TG------------AALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQR 301

Query: 366 KPTLATRTAQPDHTQA-PTKQEAGGGFVLPPPG--TDLVFLREG-------ASSPVQVPG 415
             +++ R + P    A P K   G G V P     T ++    G       A  P+  P 
Sbjct: 302 TTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPP 361

Query: 416 PVAASTEALLQAVDPGLPSVKQEPPDPEEDKEENKDD 452
           PV+ S    +    PG+P V ++       K +N +D
Sbjct: 362 PVSKSDVKPV----PGVPGVCRKTKKKHLKKSKNPED 394


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 57/187 (30%), Positives = 68/187 (36%), Gaps = 42/187 (22%)

Query: 269 RRKGGCDSKMAARRRPGAQPLPPPP--PSQSPEPTEPHP-RALAPSPPAEFIYYCVDEDE 325
           +R+ GC+S+      P   PLPPPP  P   P P  P P   LA SPP +          
Sbjct: 228 KRRRGCNSEQTGL--PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQL--------- 276

Query: 326 LKRLLPSVWSESEDGA------GSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHT 379
                P +WS     A      GS PP R+ +R S        P   P  A     P H 
Sbjct: 277 ---TKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPH-----PYPYPAPAYTAHPPGHR 328

Query: 380 QAPTKQEAGG--------GFVLP---PPGTDLVFLREGASSPVQVPGPVAASTEALLQAV 428
             P      G           LP   PPG+DL   R   S       P AA+T  +  A 
Sbjct: 329 LVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSP-AATTACVPYAP 387

Query: 429 D--PGLP 433
              PGLP
Sbjct: 388 SRPPGLP 394



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 54/210 (25%), Positives = 82/210 (39%), Gaps = 39/210 (18%)

Query: 281 RRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDG 340
           ++ P A P PPPP ++ P P++P P    P  PA           LK L   +  +    
Sbjct: 769 KKPPPALP-PPPPLAKFPPPSQPQPPPPPPPSPASL---------LKSLASVLEGQKYCY 818

Query: 341 AGSPPPYRRRKRPSSARRHHLGP-----TLKPTLATRTA----QPDHTQAPTKQEAGGGF 391
            G+      R  P    ++  GP      L PT A  +A    QP  + +     +GG +
Sbjct: 819 RGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPW 878

Query: 392 VLP-PPGTDLVFLREGASSPVQVPGPV----AASTEALLQAVDPGLPSVKQ-------EP 439
                 G + V    G  +P Q P P+    A S   +L+ +     ++ +       +P
Sbjct: 879 ARERRAGEEPV---PGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDP 935

Query: 440 PDPEEDKEENKDDSASKLAP----EEEAGG 465
            DP  D  E  D    +L P    +EEAGG
Sbjct: 936 ADP-VDTAEPADSGTERLLPPAQAKEEAGG 964



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 49/173 (28%), Positives = 57/173 (32%), Gaps = 42/173 (24%)

Query: 284 PGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGA-- 341
           P A P    PP  S  P  P PR L P PP  ++             P+  +  EDG   
Sbjct: 453 PAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKG-----------PACRAAREDGEIL 501

Query: 342 -----GSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPP 396
                G+  P R    P   R   LGP   P         D    PT          P P
Sbjct: 502 EELFFGTEGPPRPAPPPLPHREGFLGP---PASRFSVGTQDSHTPPTP---------PTP 549

Query: 397 GTDLVFLREGASS-----PVQVPGP--VAASTEALLQAVDPGLPSVKQEPPDP 442
            T       G+ S     PV  P P  +A S + L     P  PS  Q P DP
Sbjct: 550 TTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPL-----PRPPSPAQNPQDP 597



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 7/52 (13%)

Query: 269  RRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEP-------HPRALAPSPP 313
            R K   D   A++ +P   P PP  P+ S +PT P         R  AP PP
Sbjct: 1031 REKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPP 1082



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 26/96 (27%), Positives = 37/96 (38%), Gaps = 20/96 (20%)

Query: 246 PPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHP 305
           PP P  R  W       L G      G C + +     P   PLPP   S S  P++P+ 
Sbjct: 32  PPHPPPRSAW-------LPG------GRCSASIGQPPLPA--PLPPSHGSSSGHPSKPYY 76

Query: 306 RALAPSP-----PAEFIYYCVDEDELKRLLPSVWSE 336
              AP+P       E ++ CV     +   P +W +
Sbjct: 77  APGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQ 112



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 15/30 (50%), Positives = 20/30 (66%), Gaps = 3/30 (10%)

Query: 288 PLP-PPPPSQSPE--PTEPHPRALAPSPPA 314
           PLP PP P+Q+P+  P  P   AL P+PP+
Sbjct: 583 PLPRPPSPAQNPQDPPLVPLTLALPPAPPS 612



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 50/197 (25%), Positives = 67/197 (34%), Gaps = 40/197 (20%)

Query: 269 RRKGGCDSKMAARRRPGAQPLPPPPP-SQSPEPTEP--------HPRA--LAPSP----- 312
           RR      +++  + P   P PPP P S++P+P  P         PR     P+P     
Sbjct: 623 RRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQF 682

Query: 313 --PAEF---------IYYCVDEDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHL 361
             PAEF         I   +DE   K        + E G    PP    K P ++ +   
Sbjct: 683 EEPAEFKILPDGLANIMKMLDESIRKE---EEQQQHEAGVAPQPPL---KEPFASLQSPF 736

Query: 362 GPTLKPT-------LATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVP 414
                PT       + T T     T A  ++E      LPPP     F       P   P
Sbjct: 737 PTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPP 796

Query: 415 GPVAASTEALLQAVDPG 431
            P  AS    L +V  G
Sbjct: 797 PPSPASLLKSLASVLEG 813


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 49/178 (27%), Positives = 67/178 (37%), Gaps = 34/178 (19%)

Query: 269  RRKGGCDSKMAA---RRRPGAQPLPPPPP-----SQSPEPTEPHPRALAPSPPAEFIYYC 320
            RR G   + ++A      P   P PPP P     + S +P E  P    P PPA      
Sbjct: 1675 RRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPA------ 1728

Query: 321  VDEDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQ 380
                E   LL  V  E E          R +RP    R   G   +P  +  T QP  ++
Sbjct: 1729 ---PEKPSLLRPVEKEKE-----KEKVTRGERPLRGERATSGRQTRPERSLATGQPATSR 1780

Query: 381  ----APTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPS 434
                 PTK +A      PPP     +L+E   +     GP  +S+++      PG PS
Sbjct: 1781 LPKARPTKVKAE-----PPPKKRKKWLKEAGGNATAGGGPPGSSSDS---ESSPGAPS 1830



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 35/106 (33%), Positives = 45/106 (42%), Gaps = 13/106 (12%)

Query: 284  PGAQPLPPPPPSQSPEPTEPHPRALAP--SPPAEFIYYCVDEDEL----------KRLLP 331
            P   PLPPPPP   P P  P P A AP  +PP E      ++ EL          K+   
Sbjct: 1496 PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETA 1555

Query: 332  SVWSESEDGAG-SPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQP 376
            +V  E+++ AG S      R+R     R    P+LK  L T    P
Sbjct: 1556 AVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPP 1601



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 29/124 (23%), Positives = 38/124 (30%), Gaps = 22/124 (17%)

Query: 263  LRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVD 322
            L G  +    G         +P   P P P P   P P  P P+   PSPP         
Sbjct: 1436 LPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPP--------- 1486

Query: 323  EDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAP 382
                  + P+  S        PPP      P         P   P  A   A P+   AP
Sbjct: 1487 ----PLVAPTPSSPPPPPLPPPPPPAMPSPP---------PPPPPAAAPLAAPPEEPAAP 1533

Query: 383  TKQE 386
            + ++
Sbjct: 1534 SPED 1537



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 55/196 (28%), Positives = 68/196 (34%), Gaps = 61/196 (31%)

Query: 288 PLPPPPPSQSPEPTEPH-----------PRALAPSPPAEFIYYCVDEDELKRLLPSVWSE 336
           P PPPP +QS +PT PH           P  L P PP              +LLPSV S 
Sbjct: 764 PPPPPPTAQSTQPT-PHGLLLEAGGPDLPLVLPPPPP--------------QLLPSVLSH 808

Query: 337 SEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPP 396
               A SP P       S    H L P      ATR   P     P           PPP
Sbjct: 809 ----APSPSP-----SASKVGVHLLEP------ATRDGAPQPPPPPPP---------PPP 844

Query: 397 GTDL---VFLREGASSPVQVPGPVAASTEAL--LQAVDPGLPSVKQEPPDPEE-----DK 446
              L     LR     P   P P     E+L    A+   L +++  PP P +       
Sbjct: 845 PMPLQLEAHLRSHGLEPA-APSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPN 903

Query: 447 EENKDDSASKLAPEEE 462
            E KD + +  +P  +
Sbjct: 904 SEGKDPAGAYRSPSPQ 919



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 63/235 (26%), Positives = 80/235 (34%), Gaps = 42/235 (17%)

Query: 241  PICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEP 300
            P+ L PP P L      V         +  K G      A R    QP PPPPP   P P
Sbjct: 791  PLVLPPPPPQLLPS---VLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMP 847

Query: 301  --TEPHPRA-----LAPSP---PAEFIYYCVDEDELKRLL-PSVWSESEDGAGSPPPYRR 349
               E H R+      APSP   P E +       EL   L P   +  + G G  PP   
Sbjct: 848  LQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVG--PPNSE 905

Query: 350  RKRPSSARRHHLGPTLKPTLATR-------------TAQPDHTQAPTKQEAGGG-----F 391
             K P+ A R    P+ + T A R                 + +  PT +E  GG     +
Sbjct: 906  GKDPAGAYR---SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDY 962

Query: 392  VLPPPGTDLVFLREGASSPVQVP-----GPVAASTEALLQAVDPGLPSVKQEPPD 441
                P  D    + GA  P   P     GP      +      PGL     +PP+
Sbjct: 963  GKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPE 1017



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 13/81 (16%)

Query: 283 RPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAG 342
           RPG  P PPPPP   P        + A +  AE            +  P +++ S    G
Sbjct: 228 RPGP-PDPPPPPRHLPTQFNLLASSSAAAAAAE------------QSSPQLYNFSGAAPG 274

Query: 343 SPPPYRRRKRPSSARRHHLGP 363
            PPP R   R  +  +H+  P
Sbjct: 275 PPPPERALPRQDTVIKHYQRP 295


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 41/202 (20%)

Query: 288  PLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSPP-P 346
            P PP PP   P PT P  ++    PP   +            +PSV  +       PP P
Sbjct: 826  PSPPTPPVPVPPPTLPKQQSFCAKPPPSPL----------SPVPSVVKQIASQFPPPPTP 875

Query: 347  YRRRKRPSSARRHHLGPTLKPTLATRTA-QPDHTQAPTKQEAGGGFVLPPPGTDLVFLRE 405
                 +P      ++ P   P +  +   QP     P+       F  PPP + LVF   
Sbjct: 876  PAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPD-----FPPPPPESSLVF-PP 929

Query: 406  GASSPVQVPGPVAASTEALL--QAVDPG-------LPSVKQEPPDPE------------- 443
               SPV  P P    T +    ++  PG        P  K+ PP P+             
Sbjct: 930  PPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEH 989

Query: 444  -EDKEENKDDSASKLAPEEEAG 464
             E K  + D   SK  P  E+G
Sbjct: 990  PEPKRPSVDSLVSKFTPPAESG 1011



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 45/172 (26%), Positives = 61/172 (35%), Gaps = 37/172 (21%)

Query: 290  PPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSPPPYRR 349
            PPPPPS  P P  P P   +P+P           D+           S  G   PPP  +
Sbjct: 928  PPPPPSPVPAPPPPPPPTASPTP-----------DKSGSPGKKTSKTSSPGGKKPPPTPQ 976

Query: 350  RKR--PSSARRHHLGPTLK--PTLATRTAQPDHTQAPTKQEAGGGFVLPPP--------- 396
            R     SS+   H  P      +L ++   P  + +P+K+       LPPP         
Sbjct: 977  RNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKE------TLPPPAAPPKPGKL 1030

Query: 397  ---GTDLV-FLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEE 444
               G +L   L++G    V    PV +          P  PS    PP P E
Sbjct: 1031 NLSGVNLPGVLQQGC---VSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPE 1079



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 42/169 (24%), Positives = 55/169 (32%), Gaps = 51/169 (30%)

Query: 279 AARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESE 338
           A++  P   P PPPPP   P P         P PP                 P + S+S 
Sbjct: 621 ASQPSPPLPPPPPPPPPPPPPP---------PPPP-----------------PPLPSQSA 654

Query: 339 DGAGSPPP----YRRRKRPSSARRHH---LGPTLKPTLATRTAQPDHTQAPTKQEAGGGF 391
             AGS  P    Y    R  +A +H      P   P + +++ +P     P       G 
Sbjct: 655 PSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP------NGV 708

Query: 392 VLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPP 440
           V PPP             P   P P +A  +       P LP     PP
Sbjct: 709 VPPPP------------PPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP 745



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 46/161 (28%), Positives = 64/161 (39%), Gaps = 18/161 (11%)

Query: 288  PLPPPPPSQSPEPTEPHPRALAP-SPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSPPP 346
            P PP PP+   +P +P P  +AP SPPA        + + K    S+   S D    PP 
Sbjct: 870  PPPPTPPAMESQPLKPVPANVAPQSPPAV-------KAKPKWQPSSIPVPSPDFPPPPPE 922

Query: 347  YRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAP---TKQEAGGGFVLPPPGTDLVFL 403
                  P         P   P  A+ T  PD + +P   T + +  G   PPP T     
Sbjct: 923  SSLVFPPPPPSPVPAPPPPPPPTASPT--PDKSGSPGKKTSKTSSPGGKKPPP-TPQRNS 979

Query: 404  REGASSPVQVPGPVAASTEALLQAVDP----GLPSVKQEPP 440
               +SS  + P P   S ++L+    P    G PS +  PP
Sbjct: 980  SIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP 1020



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 35/138 (25%), Positives = 49/138 (35%), Gaps = 19/138 (13%)

Query: 246  PPRPGLRRQWKC-----VQRRCLRGKHARRKG-GCDSKMAARRRPGAQPLPPPPPSQSPE 299
            PP+PG            +Q+ C+  K     G G DS +     P     PPPPP     
Sbjct: 1024 PPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETE-- 1081

Query: 300  PTEPHPRALAPSPPAEF--IYYCVDEDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSAR 357
                      P PP E   ++      ++  + P     S+      PP  R KR  S R
Sbjct: 1082 ---------LPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTR 1132

Query: 358  RHHLGPTLKPTLATRTAQ 375
                  + +PT+AT   Q
Sbjct: 1133 LTQAEISEQPTMATVVPQ 1150


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 52/192 (27%), Positives = 65/192 (33%), Gaps = 46/192 (23%)

Query: 290  PPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGA-------- 341
            P PPP   P P E  PR L P+PP              R  P V  E E GA        
Sbjct: 1172 PQPPPPPLPPPPEAQPRRLEPAPP--------------RARPEVAPEGEPGAPDSRAGGD 1217

Query: 342  ------GSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPP 395
                  G PP   R+           GP + P L      P       K       +  P
Sbjct: 1218 TALSGDGDPPKPERK-----------GPEM-PRLFLDLGPPQGNSEQIKARLSRLSLALP 1265

Query: 396  PGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDKEENKDDSAS 455
            P T   F   G   P   P   A +  A  +A   G P   +E  + E++ EE  +++A 
Sbjct: 1266 PLTLTPFPGPGPRRP---PWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAA- 1321

Query: 456  KLAPEEEAGGAG 467
              AP   AG  G
Sbjct: 1322 --APGAAAGPRG 1331



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 16/36 (44%), Positives = 19/36 (52%), Gaps = 1/36 (2%)

Query: 279 AARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPA 314
           AA + PG  P PP PP   P P  P   A +P PP+
Sbjct: 769 AAPQYPGRGP-PPAPPPPPPPPRAPADPAASPDPPS 803



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 14/32 (43%), Positives = 19/32 (59%)

Query: 392  VLPPPGTDLVFLREGASSPVQVPGPVAASTEA 423
            +LPPPG  L F R   S  ++ PGP A + +A
Sbjct: 1450 LLPPPGPPLCFSRFSVSPALETPGPPARAPDA 1481



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 51/227 (22%), Positives = 82/227 (36%), Gaps = 42/227 (18%)

Query: 255 WKCVQRRCLRGKHARRKGGCDSKMAAR----RRPGAQPLPPPPPSQSPEP-------TEP 303
           W  + + C R   A+R    D ++        RP   P PPPPP   P P       + P
Sbjct: 413 WYDILQSCWRPP-AQRPSASDLQLQLTYLLSERPPRPPPPPPPPRDGPFPWPWPPAHSAP 471

Query: 304 HPRALAPSPPAEFIYYCVDEDELKRL--------LPSVWSESEDGA---GSPPPYRRRKR 352
            P  L+   P    +   D D++  +        L  +W ++  GA   G  P ++    
Sbjct: 472 RPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASA 531

Query: 353 PSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQ 412
           P +   +   P  +  L+T +  P  +              P   ++     E   SP  
Sbjct: 532 PPAPHANPSNPFYE-ALSTPSVLPVISARS-----------PSVSSEYYIRLEEHGSP-- 577

Query: 413 VPGPVAASTEALLQAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAP 459
            P P+  +       +DPG+P+  Q P  P E  +   +  AS L P
Sbjct: 578 -PEPLFPND---WDPLDPGVPA-PQAPQAPSEVPQLVSETWASPLFP 619



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 15/42 (35%), Positives = 18/42 (42%), Gaps = 1/42 (2%)

Query: 272 GGCDSKMAARRRPGAQPLPPPPPSQSPEP-TEPHPRALAPSP 312
           G    +   R  P A P PPPPP    +P   P P +   SP
Sbjct: 767 GAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASP 808



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 64/246 (26%), Positives = 86/246 (34%), Gaps = 46/246 (18%)

Query: 244  LRPPRPGLRRQWKCVQRRCLRGKHARRK----GGCD--------SKMAARRRPGAQPLPP 291
            L PPR    R+ K ++   LR   A  K    GG          S+    R P     PP
Sbjct: 993  LTPPR----REEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPP 1048

Query: 292  PP-PSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRL-LPSVWSESEDGAGS------ 343
               P ++P P E  P +  P+P    I     E  L+R   PS    S +G  +      
Sbjct: 1049 ETGPWRAPGPWEKTPESWGPAPT---IGEPAPETSLERAPAPSAVVSSRNGGETAPGPLG 1105

Query: 344  PPPYRRRKRPSSARR-HHLGPTLKPTLATRTAQPDHTQAP--TKQEAGGGFVLPPPGTDL 400
            P P      P + RR    G   +   A R       +AP  T    GGG   P  G D 
Sbjct: 1106 PAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGG---PGSGVDA 1162

Query: 401  VFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQE-PPDPEEDKEENKDDSASKLAP 459
                   + P   P P+    EA  + ++P  P  + E  P+ E              AP
Sbjct: 1163 KAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPG------------AP 1210

Query: 460  EEEAGG 465
            +  AGG
Sbjct: 1211 DSRAGG 1216


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 60/250 (24%), Positives = 83/250 (33%), Gaps = 31/250 (12%)

Query: 225 CGVCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRP 284
           C VC  C+       C  C       L   W C  + C+  +   ++ G        +  
Sbjct: 112 CVVCEDCKKNV----CTKCGVETNNRLHSVWLC--KICIEQREVWKRSGAWFFKGFPK-- 163

Query: 285 GAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSP 344
             Q LP P P +  +P +P     AP  PA        E +     P+   +SED  G  
Sbjct: 164 --QVLPQPMPIKKTKPQQPVSEPAAPEQPA-------PEPKHPARAPA-RGDSEDRRG-- 211

Query: 345 PPYRRRKRPSSA-RRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFL 403
           P  +    P+SA  R + GP ++     R +             G G     P      L
Sbjct: 212 PGQKTGPDPASAPGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAG----L 267

Query: 404 REGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDP----EEDKEENKDDSASKLAP 459
           R   S     P P +  + A  Q   PG P   +  P P     + K E         AP
Sbjct: 268 RRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAP 327

Query: 460 --EEEAGGAG 467
             EE  GG G
Sbjct: 328 PREERTGGVG 337



 Score = 35.8 bits (81), Expect = 0.093
 Identities = 78/310 (25%), Positives = 113/310 (36%), Gaps = 55/310 (17%)

Query: 176 CGEC-----AACQVTEDC--GACSTCLLQLPHDVASGLFCKCERRRCL--RIVERSRGCG 226
           CGE      +AC V EDC    C+ C ++  + + S   CK     C+  R V +  G  
Sbjct: 101 CGEQLGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKI----CIEQREVWKRSGAW 156

Query: 227 VCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARR---KGGCDSKMAARRR 283
             +G   Q      PI    P+  +       ++     KH  R   +G  + +    ++
Sbjct: 157 FFKGFPKQVLPQPMPIKKTKPQQPVSEP-AAPEQPAPEPKHPARAPARGDSEDRRGPGQK 215

Query: 284 PGAQPLPPP------PP---------SQSPEPTEP--HPRALAPSPPAEFIYYCVDEDEL 326
            G  P   P      PP         S S   +E   H      S  +       +  + 
Sbjct: 216 TGPDPASAPGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQA 275

Query: 327 KRLLP-SVWSESEDGAGSP-PPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTK 384
            R  P SV S +    G P  P   R  P  A R    P  KP +A   + P  T  P +
Sbjct: 276 SRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRF---PDQKPEVAP--SDPGTTAPPRE 330

Query: 385 QEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEE 444
           +  GG    P  G      RE   S     GP + ++ A  Q      P+  ++PP PEE
Sbjct: 331 ERTGGVGGYPAVGA-----REDRMS--HPSGPYSQASAAAPQ------PAAARQPPPPEE 377

Query: 445 DKEE-NKDDS 453
           ++EE N  DS
Sbjct: 378 EEEEANSYDS 387


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 60/250 (24%), Positives = 83/250 (33%), Gaps = 31/250 (12%)

Query: 225 CGVCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRP 284
           C VC  C+       C  C       L   W C  + C+  +   ++ G        +  
Sbjct: 108 CVVCEDCKKNV----CTKCGVETNNRLHSVWLC--KICIEQREVWKRSGAWFFKGFPK-- 159

Query: 285 GAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSP 344
             Q LP P P +  +P +P     AP  PA        E +     P+   +SED  G  
Sbjct: 160 --QVLPQPMPIKKTKPQQPVSEPAAPEQPA-------PEPKHPARAPA-RGDSEDRRG-- 207

Query: 345 PPYRRRKRPSSA-RRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFL 403
           P  +    P+SA  R + GP ++     R +             G G     P      L
Sbjct: 208 PGQKTGPDPASAPGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAG----L 263

Query: 404 REGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDP----EEDKEENKDDSASKLAP 459
           R   S     P P +  + A  Q   PG P   +  P P     + K E         AP
Sbjct: 264 RRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAP 323

Query: 460 --EEEAGGAG 467
             EE  GG G
Sbjct: 324 PREERTGGVG 333



 Score = 35.8 bits (81), Expect = 0.093
 Identities = 78/310 (25%), Positives = 113/310 (36%), Gaps = 55/310 (17%)

Query: 176 CGEC-----AACQVTEDC--GACSTCLLQLPHDVASGLFCKCERRRCL--RIVERSRGCG 226
           CGE      +AC V EDC    C+ C ++  + + S   CK     C+  R V +  G  
Sbjct: 97  CGEQLGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKI----CIEQREVWKRSGAW 152

Query: 227 VCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARR---KGGCDSKMAARRR 283
             +G   Q      PI    P+  +       ++     KH  R   +G  + +    ++
Sbjct: 153 FFKGFPKQVLPQPMPIKKTKPQQPVSEP-AAPEQPAPEPKHPARAPARGDSEDRRGPGQK 211

Query: 284 PGAQPLPPP------PP---------SQSPEPTEP--HPRALAPSPPAEFIYYCVDEDEL 326
            G  P   P      PP         S S   +E   H      S  +       +  + 
Sbjct: 212 TGPDPASAPGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQA 271

Query: 327 KRLLP-SVWSESEDGAGSP-PPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTK 384
            R  P SV S +    G P  P   R  P  A R    P  KP +A   + P  T  P +
Sbjct: 272 SRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRF---PDQKPEVAP--SDPGTTAPPRE 326

Query: 385 QEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEE 444
           +  GG    P  G      RE   S     GP + ++ A  Q      P+  ++PP PEE
Sbjct: 327 ERTGGVGGYPAVGA-----REDRMS--HPSGPYSQASAAAPQ------PAAARQPPPPEE 373

Query: 445 DKEE-NKDDS 453
           ++EE N  DS
Sbjct: 374 EEEEANSYDS 383


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 54/194 (27%), Positives = 65/194 (33%), Gaps = 11/194 (5%)

Query: 279 AARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESE 338
           AAR  P    +P PPP   P P  P P  L  S P +           K  LP V     
Sbjct: 161 AARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVP 220

Query: 339 DGAGSPPPYRRRKRPSSARRHHLG-PTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPG 397
                PPP      P       L    +KP LA     P     P     G   +   P 
Sbjct: 221 CAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPA 280

Query: 398 TDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSV--KQEPPDPEEDKEENKDDSAS 455
           +     +E  + P  +P   + S  A L A  P LP V    E P P   K      S S
Sbjct: 281 SPAQDAQEPPAPPPPLPPYASCSPRASLPA--PPLPGVNSSSETPPPLPPK------SPS 332

Query: 456 KLAPEEEAGGAGTP 469
             AP ++AG    P
Sbjct: 333 FQAPPQKAGAQALP 346



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 17/44 (38%), Positives = 19/44 (43%), Gaps = 2/44 (4%)

Query: 288 PLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLP 331
           P+PPPPP   P P  P P    P PP        D   L+R  P
Sbjct: 2   PVPPPPPPPLPPP--PPPLGAPPPPPPSAPPVSTDTSSLRRADP 43


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 57/226 (25%), Positives = 79/226 (34%), Gaps = 35/226 (15%)

Query: 275 DSKMAARRRPGAQPLPPPPPSQSPEP---TEPHPRALAPSPPAEFIYYCVDEDEL---KR 328
           + K   + +PG     PPP +  P+    T+P  +A+    P E      DE +    + 
Sbjct: 277 EQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEE 336

Query: 329 LLPSVWSESEDGAGSPPPYRRRKRPSS------------ARRHHLGPTL----KPTLATR 372
             P   +        PPP ++    SS            A     G T     KP + T+
Sbjct: 337 KKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTK 396

Query: 373 TAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSP--------VQVPGPVAASTEAL 424
           +       AP KQ  GGG  L     D     E +SS         V    P A +  AL
Sbjct: 397 SPAVKPAAAP-KQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAAL 455

Query: 425 L----QAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGA 466
                QA      S         E++EE    SA K  P++ AGGA
Sbjct: 456 SLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGA 501


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 67/288 (23%), Positives = 106/288 (36%), Gaps = 45/288 (15%)

Query: 210 CERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLR--RQWKCVQ---RRCLR 264
           C     L  V        C  CQT      C +C   P P L   ++W C+    +R L 
Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTV----CSLCGFNPNPHLTEVKEWLCLNCQMKRALG 647

Query: 265 GKHARRKGGCDSKM--------AARRRPGAQPLPPPPP---------SQSPEPTEPHPRA 307
           G  A        K+        +A  +   QP    P          S++PEP +P P  
Sbjct: 648 GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707

Query: 308 LAPS---PPAEFIYYCVDEDELKRLLP----SVWSESEDG--AGSPPPYRRRKRPSSARR 358
             P+    P+       + D L +  P    SV SE +    A   P   +  +P++   
Sbjct: 708 KQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767

Query: 359 HHLGPTLKPTLATRTAQP---DHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPG 415
                T KP + +   Q    + T  P K ++       PP  + V   +  +    +P 
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKA----IPR 823

Query: 416 PVAASTEALLQAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEA 463
           P  AS   ++    P   S  Q+  DP + KEE K  + +K++P+ +A
Sbjct: 824 P--ASDSKIISHPGPSSESKGQKQVDPVQKKEEPK-KAQTKMSPKPDA 868



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 45/164 (27%), Positives = 62/164 (37%), Gaps = 42/164 (25%)

Query: 284 PGAQPLPPPPPSQSP--EPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGA 341
           P  QP P  PP+Q P  E ++P P      PPA+          L + L       + G 
Sbjct: 305 PIQQPTPGKPPAQQPGHEKSQPGP----AKPPAQ-------PSGLTKPL-----AQQPGT 348

Query: 342 GSPP--PYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTD 399
             PP  P    K P+      LGP   P      AQ   ++ P+ ++ G   +  PPG  
Sbjct: 349 VKPPVQPPGTTKPPAQP----LGPAKPP------AQQTGSEKPSSEQPGPKALAQPPGV- 397

Query: 400 LVFLREGASSPVQVPGPVAASTEAL----LQAVDPGLPSVKQEP 439
                    +P Q PGP    T+ +      A  PGL S  + P
Sbjct: 398 -------GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 46/192 (23%), Positives = 62/192 (32%), Gaps = 22/192 (11%)

Query: 283 RPGAQPLPPPPP------SQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSE 336
           +P AQPL P  P      S+ P   +P P+ALA  P            +     P     
Sbjct: 360 KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV---------GKTPAQQPGPAKP 410

Query: 337 SEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQ-PDHTQAPTKQEAGGGFVLPP 395
                G+P P  ++    S  +   GPT  P       + P     P K  A       P
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAKAP-GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469

Query: 396 PGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPG-LPSVKQEPPDPEEDKEENKDDSA 454
           P      L   A  P Q PGP     +    A  P   P   + PP      + +     
Sbjct: 470 PSQ----LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525

Query: 455 SKLAPEEEAGGA 466
           S   P ++ G A
Sbjct: 526 STKPPSQQPGSA 537



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 53/222 (23%), Positives = 76/222 (34%), Gaps = 50/222 (22%)

Query: 265 GKHARRKGGCDSKMAARRRPGAQP--LPPP---------PPSQSPEPTEPHPRALAPSPP 313
           GK   ++ G +       +P AQP  L  P         PP Q P  T+P  + L P+ P
Sbjct: 312 GKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKP 371

Query: 314 AEFIYYCVDEDELKRLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRT 373
                            P+  + SE  +   P  +   +P    +    P  +P  A   
Sbjct: 372 -----------------PAQQTGSEKPSSEQPGPKALAQPPGVGK---TPAQQPGPAKPP 411

Query: 374 AQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLP 433
            Q   T  P  Q+ G       PG           +PVQ PGP     +   Q   PG  
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGP--------TKTPVQQPGP----GKIPAQQAGPGKT 459

Query: 434 SVKQ----EPPD--PEEDKEENKDDSASKLAPEEEAGGAGTP 469
           S +Q    +PP   P   K   +    +K  P ++ G A  P
Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPAK-PPPQQPGSAKPP 500



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 37/147 (25%), Positives = 55/147 (37%), Gaps = 24/147 (16%)

Query: 290 PPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDEDELKRLLPSVWSESEDGAGSPPPYRR 349
           P  PPSQ P P +P P+   P+ P         +       PS     + G+  PPP  +
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPP-------PQQPGSAKPPS----QQPGSTKPPP--Q 512

Query: 350 RKRPSSARRHHLGPTLKPTLATRTAQPDHTQ-APTKQEA----------GGGFVLPPPGT 398
           +  P+       G T  P+    +A+P   Q +P K  A          G G  L PP  
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTV 572

Query: 399 DLVFLREGASSPVQVPGPVAASTEALL 425
                +  +    +   P+  +TE LL
Sbjct: 573 SPSAKQPPSQGLPKTICPLCNTTELLL 599



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 14/35 (40%), Positives = 18/35 (51%)

Query: 278  MAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSP 312
            ++A+  P   P PPPPP   P P  P P   +P P
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP 2435



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 19/47 (40%), Positives = 21/47 (44%), Gaps = 13/47 (27%)

Query: 276  SKMAARRRP---------GAQPLPPPPPSQSPEPTEPHPRALAPSPP 313
            S + A+ RP          AQP PPPPP   P P  P P    P PP
Sbjct: 2384 SSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP----PPPP 2426



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 17/149 (11%)

Query: 284  PGAQPLPPPPPSQSPEPTEPHPRAL--------APSPPAEFIYYCVDEDELKRLLPS--- 332
            P   P PPPPP   P PT P P  L        +P   A  ++  V   E   +L S   
Sbjct: 2414 PPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL 2473

Query: 333  VWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFV 392
              +     A  P P +    PS     H     KP +A +   P   Q PT  +      
Sbjct: 2474 PVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIP---QLPTTTQKPTDIH 2530

Query: 393  LPPPG---TDLVFLREGASSPVQVPGPVA 418
              P G   T  + L    S+  ++P P +
Sbjct: 2531 PKPTGLSLTSSMTLNLVTSADYKLPSPTS 2559



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 14/37 (37%), Positives = 16/37 (43%)

Query: 276  SKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSP 312
            S +    +P   P PPPPP   P P  P P     SP
Sbjct: 2397 SSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 12/26 (46%), Positives = 13/26 (50%)

Query: 288  PLPPPPPSQSPEPTEPHPRALAPSPP 313
            P PPPPP   P P  P P    P+ P
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPTSP 2433



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 12/28 (42%), Positives = 14/28 (50%)

Query: 284  PGAQPLPPPPPSQSPEPTEPHPRALAPS 311
            P   P PPPPP   P P  P P +  P+
Sbjct: 2409 PPPPPPPPPPPPPPPPPPLPPPTSPKPT 2436


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,262,186
Number of Sequences: 37866
Number of extensions: 1806921
Number of successful extensions: 23063
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 306
Number of HSP's successfully gapped in prelim test: 691
Number of HSP's that attempted gapping in prelim test: 15441
Number of HSP's gapped (non-prelim): 5875
length of query: 503
length of database: 18,247,518
effective HSP length: 107
effective length of query: 396
effective length of database: 14,195,856
effective search space: 5621558976
effective search space used: 5621558976
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.