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Search of human proteins with 7706589
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706589 GNAS complex locus NESP55 [Homo sapiens]
(245 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706589 GNAS complex locus NESP55 [Homo sapiens] 503 e-143
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 52 5e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 50 2e-06
gi|47578107 delangin isoform B [Homo sapiens] 49 4e-06
gi|47578105 delangin isoform A [Homo sapiens] 49 4e-06
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 48 9e-06
gi|21361639 DIPB protein [Homo sapiens] 48 9e-06
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 47 2e-05
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 47 2e-05
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 47 2e-05
gi|210032580 SET domain containing 1B [Homo sapiens] 47 2e-05
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 47 2e-05
gi|30795231 brain abundant, membrane attached signal protein 1 [... 46 3e-05
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 46 3e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 46 3e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 46 3e-05
gi|122937247 unc-13 homolog A [Homo sapiens] 46 3e-05
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 45 4e-05
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 45 4e-05
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 45 4e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 4e-05
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 4e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 4e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 4e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 4e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 45 6e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 45 6e-05
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 45 7e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 44 1e-04
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 44 1e-04
>gi|7706589 GNAS complex locus NESP55 [Homo sapiens]
Length = 245
Score = 503 bits (1295), Expect = e-143
Identities = 245/245 (100%), Positives = 245/245 (100%)
Query: 1 MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRAAAQQ 60
MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRAAAQQ
Sbjct: 1 MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALATSNARAQQRAAAQQ 60
Query: 61 RRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIE 120
RRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIE
Sbjct: 61 RRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIE 120
Query: 121 SETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPP 180
SETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPP
Sbjct: 121 SETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPP 180
Query: 181 STQEPQSPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPI 240
STQEPQSPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPI
Sbjct: 181 STQEPQSPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPI 240
Query: 241 PIRRH 245
PIRRH
Sbjct: 241 PIRRH 245
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 52.0 bits (123), Expect = 5e-07
Identities = 44/176 (25%), Positives = 69/176 (39%), Gaps = 16/176 (9%)
Query: 70 RSGAQVFPE---SPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFE 126
RS A FPE SP E E+A L E+ E E + E++S E
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAKSPLK-------EDAKAPEKEIPKKEEVKSPVKEE 827
Query: 127 TEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQ 186
+P+ EP + E+++ P PK S + + P + P + +
Sbjct: 828 EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE 887
Query: 187 SPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTR------RDASPESPSK 236
S E ++ + EDK E + P + + + KPK+ T DA + PSK
Sbjct: 888 SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943
Score = 48.9 bits (115), Expect = 4e-06
Identities = 39/146 (26%), Positives = 63/146 (43%), Gaps = 13/146 (8%)
Query: 104 EEEFDYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRL 163
EE+ +SE E+ I E ET+ T E E E +++ G K G+
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEG----KEEEGGEEEEAEG 496
Query: 164 HALKLRSPDASPSRAP------PSTQEPQSPREGEELKPEDKDPRDPEESKEPKEEKQRR 217
+ +SP A + +P P +E +SP E + PE ++ + P E K P++ K
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAK--SPEKEEAKSPAEVKSPEKAKSPA 554
Query: 218 RCKPKKPTRRDASPESPSKKGPIPIR 243
+ + K P SPE K P ++
Sbjct: 555 KEEAKSPPEA-KSPEKEEAKSPAEVK 579
Score = 46.2 bits (108), Expect = 3e-05
Identities = 44/162 (27%), Positives = 71/162 (43%), Gaps = 15/162 (9%)
Query: 83 ESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEPETEPE 142
E E + E++ E E +EE E E E E E E E ++ P E + +
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGG---EEETKSPPAEEAASPEK 514
Query: 143 DDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAP-PSTQEPQSPREGEELKPEDKDP 201
+ + PV + + ++ + K + SP +A P+ +E +SP PE K P
Sbjct: 515 EAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP-------PEAKSP 567
Query: 202 RDPEESKEPKEEKQRRRCK--PKKPTRRDASPESPSK-KGPI 240
+ EE+K P E K + K K+ + A +SP K K P+
Sbjct: 568 -EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV 608
Score = 45.4 bits (106), Expect = 4e-05
Identities = 41/176 (23%), Positives = 73/176 (41%), Gaps = 27/176 (15%)
Query: 78 ESPESESDHEHEEAD----LELSLPECLEYEEEFDYETESETESEIESETDFETEPETAP 133
+SPE E E+A E PE + + + ++ + +S ++ E E +P
Sbjct: 653 KSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK-SPEKAKSP 711
Query: 134 TTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEE 193
E PE + PV + T K +SP +++P + P+ + +
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKT----------PEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761
Query: 194 LKPEDKDP----------RDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGP 239
PE K P + PE++K P +E+ + K K P + DA ++P K+ P
Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDA--KAPEKEIP 815
Score = 44.7 bits (104), Expect = 7e-05
Identities = 42/168 (25%), Positives = 79/168 (47%), Gaps = 14/168 (8%)
Query: 79 SPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTE-P 137
SPE E+ +E E P + E+ + ++ +E +S ++++ + E ++ P + P
Sbjct: 511 SPEKEAKSPVKE---EAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP 567
Query: 138 ETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEE-LKP 196
E E V + + + +SP+ + S P +E +SP E + +K
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS---PVKEEAKSPAEAKSPVKE 624
Query: 197 EDKDP---RDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSK-KGPI 240
E K P + PE++K P +E+ + K K P + +A +SP K K P+
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEA--KSPEKAKSPV 670
Score = 43.9 bits (102), Expect = 1e-04
Identities = 46/191 (24%), Positives = 85/191 (44%), Gaps = 20/191 (10%)
Query: 59 QQRRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESE 118
++ +S L ++ + P+ E +S + EE E+ + E + EE +TE +
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK 856
Query: 119 IESETDFETEPETAPTTE-PETEPEDDRGPVV--PKHSTFGQSLTQRLHALKLRSPDASP 175
+S+ E AP E P+ + E+ + P V PK S + K+ +P+
Sbjct: 857 KDSKK------EEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE- 909
Query: 176 SRAPPSTQEPQSPREGEEL---KPED---KDPRDPEESK----EPKEEKQRRRCKPKKPT 225
+ A +E P+E E+ +P+D K+P P E K E K+ K+ + KP++
Sbjct: 910 APAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP 969
Query: 226 RRDASPESPSK 236
+ +A + K
Sbjct: 970 KTEAKAKEDDK 980
Score = 43.9 bits (102), Expect = 1e-04
Identities = 41/165 (24%), Positives = 73/165 (44%), Gaps = 24/165 (14%)
Query: 73 AQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETA 132
A P++ E + + E E P+ EE+ + E ES++E++ + + +
Sbjct: 847 APATPKTEEKKDSKKEEAPKKEAPKPKV---EEKKEPAVEKPKESKVEAKKEEAEDKKKV 903
Query: 133 PTTEPETEPEDD-RGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREG 191
PT E E + + + PK T + + PD + ++ EP P E
Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEKT----------EVAKKEPDDAKAK------EPSKPAEK 947
Query: 192 EELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSK 236
+E PE KD ++ E++K+P EEK + K K+ + + PSK
Sbjct: 948 KEAAPEKKDTKE-EKAKKP-EEKPKTEAKAKEDDK--TLSKEPSK 988
Score = 43.1 bits (100), Expect = 2e-04
Identities = 45/179 (25%), Positives = 78/179 (43%), Gaps = 27/179 (15%)
Query: 70 RSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEP 129
+S A+V +SPE EEA S PE E+E E+++ +E++S E
Sbjct: 539 KSPAEV--KSPEKAKSPAKEEAK---SPPEAKSPEKE-----EAKSPAEVKSP-----EK 583
Query: 130 ETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQ--- 186
+P E P + + P K ++ + + +SP +++P + P+
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA----EAKSPVKEEAKSPAEVKSPEKAK 639
Query: 187 SPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRR----DASPESPSK-KGPI 240
SP + E PE + EE+K P++ K + + K P + A +SP K K P+
Sbjct: 640 SPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698
Score = 38.5 bits (88), Expect = 0.005
Identities = 42/169 (24%), Positives = 74/169 (43%), Gaps = 18/169 (10%)
Query: 78 ESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEP 137
+SPE EEA PE + + + ++ + +S +++T PE +
Sbjct: 717 KSPEKAKSPVKEEA----KTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE 772
Query: 138 ETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKPE 197
E D+ P K + + K +SP ++AP E + P++ EE+K
Sbjct: 773 EARSPADKFPEKAKSPVKEEVKSPE----KAKSPLKEDAKAP----EKEIPKK-EEVKSP 823
Query: 198 DKDPRDPEE--SKEP--KEEKQRRRCKPKKPTRRDA-SPESPSKKGPIP 241
K+ P+E KEP K E+++ PK ++D+ E+P K+ P P
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872
Score = 31.2 bits (69), Expect = 0.86
Identities = 30/139 (21%), Positives = 65/139 (46%), Gaps = 12/139 (8%)
Query: 81 ESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDF-ETEPETAPTTEPET 139
ES+ + + EEA+ + +P E+E + E + +++ + +T+ + EP+ A EP +
Sbjct: 887 ESKVEAKKEEAEDKKKVPTP---EKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP-S 942
Query: 140 EPEDDRGPVVPKHSTFGQSLTQRLHA----LKLRSPDASPSRAPPSTQEPQSPREGEELK 195
+P + + K T + + K + D + S+ P +P++ + +
Sbjct: 943 KPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP---SKPKAEKAEKSSS 999
Query: 196 PEDKDPRDPEESKEPKEEK 214
+ KD + PE++ E K K
Sbjct: 1000 TDQKDSKPPEKATEDKAAK 1018
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 49.7 bits (117), Expect = 2e-06
Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 8/142 (5%)
Query: 78 ESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEP 137
E+PE+E + + E +E PE +E + E + E+E E + E +PE+ P
Sbjct: 1836 EAPEAEGEAQPESEGVE--APEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETP 1893
Query: 138 ETEPE---DDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGE-E 193
E E E + G P+ Q T+ + AL+ D S + + ++ +E E +
Sbjct: 1894 EAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQ 1953
Query: 194 LKPEDK--DPRDPEESKEPKEE 213
+PE + + ++ EE +P+ E
Sbjct: 1954 TQPESEVIESQEAEEEAQPESE 1975
Score = 48.1 bits (113), Expect = 7e-06
Identities = 50/189 (26%), Positives = 75/189 (39%), Gaps = 32/189 (16%)
Query: 78 ESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEP 137
E+PE+E + + E D+E E E E E+E E E E ETE A TE
Sbjct: 1875 EAPEAEGEAQPESEDVETP-----EAEWEVQPESEGAEAPEAEKEAQPETESVEALETEG 1929
Query: 138 ETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQS------PREG 191
E EPE + ++ Q ++ + A P +++ ++ +E
Sbjct: 1930 EDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEA 1989
Query: 192 E-ELKPEDKDPRDPE---ESKEPKEEKQRR----RCKPK-------------KPTRRDAS 230
E E +PE +D PE E +E +EE Q +PK + T DA
Sbjct: 1990 EGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQ 2049
Query: 231 PESPSKKGP 239
PES + P
Sbjct: 2050 PESDGVEAP 2058
Score = 47.4 bits (111), Expect = 1e-05
Identities = 61/220 (27%), Positives = 82/220 (37%), Gaps = 28/220 (12%)
Query: 42 LRALATSNARAQQRAAAQQRRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECL 101
+ AL T + A+ + + A G Q PES ES EEA E E L
Sbjct: 1922 VEALETEGEDEPESEGAEAQEAEEAAQEAEG-QTQPESEVIESQEAEEEAQPESEDVEAL 1980
Query: 102 EYE-EEFDYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLT 160
E E E + E E++ ESE + E E + A E E +PE D PK G+
Sbjct: 1981 EVEVETQEAEGEAQPESEDVEAPEAEGEMQEA---EEEAQPESDGVEAQPKSE--GEEAQ 2035
Query: 161 QRLHALKLRSPDASPSR---APPSTQEPQSPREGE------ELKPEDKD--------PRD 203
+ + DA P P +E EGE E PE +D
Sbjct: 2036 EVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQ 2095
Query: 204 PE----ESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGP 239
PE E+ E + E Q+ T +A PES + P
Sbjct: 2096 PESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAP 2135
Score = 46.6 bits (109), Expect = 2e-05
Identities = 50/195 (25%), Positives = 70/195 (35%), Gaps = 19/195 (9%)
Query: 47 TSNARAQQRAAAQQRRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEE 106
+ A + Q+ + A G + PES E+ EA E E + E E
Sbjct: 2098 SEGVEAPEAEGEAQKAEGIEAPETEG-EAQPESEGIEAPEAEGEAQPESEGVEAQDAEGE 2156
Query: 107 FDYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHAL 166
E+E E E E E E AP E E +PE + G P+ Q
Sbjct: 2157 AQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESE-GIEAPEAEGEAQ--------- 2206
Query: 167 KLRSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTR 226
P+ AP + +E Q EG E PE + PE E + EK + P+
Sbjct: 2207 ----PELEGVEAPEAEEEAQPEPEGVE-TPEAEGEAQPESEGETQGEK---KGSPQVSLG 2258
Query: 227 RDASPESPSKKGPIP 241
S E+ P+P
Sbjct: 2259 DGQSEEASESSSPVP 2273
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/164 (26%), Positives = 57/164 (34%), Gaps = 25/164 (15%)
Query: 77 PESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTE 136
PES E+ EEA EL E E E E E+E E E E E E AP E
Sbjct: 2159 PESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAE 2218
Query: 137 PETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGE-ELK 195
E +PE + + +P+A P S E Q ++G ++
Sbjct: 2219 EEAQPEPE----------------------GVETPEAEGEAQPESEGETQGEKKGSPQVS 2256
Query: 196 PEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGP 239
D + ES P E R P P S+ GP
Sbjct: 2257 LGDGQSEEASESSSPVPED--RPTPPPSPGGDTPHQRPGSQTGP 2298
Score = 43.9 bits (102), Expect = 1e-04
Identities = 45/198 (22%), Positives = 77/198 (38%), Gaps = 23/198 (11%)
Query: 47 TSNARAQQRAAAQQRRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEE 106
+ AQ ++ ++ + ++ PES E+ EEA E +E
Sbjct: 2020 SDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQ------EAEGEVQE 2073
Query: 107 FDYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHAL 166
+ E E+E E + E +PE+ PE E E + + T G++
Sbjct: 2074 AEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEA-------- 2125
Query: 167 KLRSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRDPE----ESKEPKEEKQRRRCKPK 222
P++ AP + E Q EG E + + + + PE E++E +EE Q +
Sbjct: 2126 ---QPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQ-PESEGIEAQEAEEEAQPELEGVE 2181
Query: 223 KP-TRRDASPESPSKKGP 239
P +A PES + P
Sbjct: 2182 APEAEGEAQPESEGIEAP 2199
Score = 36.6 bits (83), Expect = 0.020
Identities = 46/170 (27%), Positives = 59/170 (34%), Gaps = 47/170 (27%)
Query: 77 PESPESESDHEHEEADLELSLPECLEYEEEFDYETES----ETESEIESETDFETE---- 128
PES E+ EA EL E E EEE E E E E E + E++ ET+
Sbjct: 2191 PESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250
Query: 129 ----------------------PETAPTTEPET-------EPEDDRGPVVPKHSTFG--- 156
PE PT P P GP + S++G
Sbjct: 2251 GSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCW 2310
Query: 157 QSLTQRLHAL-KLRSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRDPE 205
Q ++ H L RSPDA ST P + R+ + PE E
Sbjct: 2311 QKDSENDHVLGDTRSPDAK------STGTPHAERKATRMYPESSTSEQEE 2354
Score = 30.4 bits (67), Expect = 1.5
Identities = 39/185 (21%), Positives = 68/185 (36%), Gaps = 27/185 (14%)
Query: 52 AQQRAAAQQRRSFL-NAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYE 110
A+ A AQ+R N+ +G+++ E E E E + S E + +
Sbjct: 1763 AEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGS-------GHEDNLQ 1815
Query: 111 TESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRS 170
E+ + + E AP E E +PE + G P+ Q
Sbjct: 1816 GEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESE-GVEAPEAEGDAQE------------ 1862
Query: 171 PDASPSRAPPSTQEPQSPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDAS 230
+ A P +++ ++P E +PE +D PE E + E + ++A
Sbjct: 1863 ---AEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEA---PEAEKEAQ 1916
Query: 231 PESPS 235
PE+ S
Sbjct: 1917 PETES 1921
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 48.9 bits (115), Expect = 4e-06
Identities = 42/179 (23%), Positives = 83/179 (46%), Gaps = 18/179 (10%)
Query: 70 RSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEP 129
+S + PE+P+ +SD E +++++ S E + + E+++ SE + ET ET+
Sbjct: 590 KSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKS-SENKLETKVETQT 648
Query: 130 ETAPTTEPETEP--EDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQS 187
E E T +++ V PK + RL K + R+ + P++
Sbjct: 649 EELKQNESRTTECKQNESTIVEPKQNE------NRLSDTKPNDNKQNNGRSETTKSRPET 702
Query: 188 PREGEELKPE------DKDPRDPEESKE--PKEEKQRRRCKPKKPTRR-DASPESPSKK 237
P++ E +PE D P P++ + P+ KQ+ +P+ P ++ + PE+P +
Sbjct: 703 PKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHR 761
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 48.9 bits (115), Expect = 4e-06
Identities = 42/179 (23%), Positives = 83/179 (46%), Gaps = 18/179 (10%)
Query: 70 RSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEP 129
+S + PE+P+ +SD E +++++ S E + + E+++ SE + ET ET+
Sbjct: 590 KSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKS-SENKLETKVETQT 648
Query: 130 ETAPTTEPETEP--EDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQS 187
E E T +++ V PK + RL K + R+ + P++
Sbjct: 649 EELKQNESRTTECKQNESTIVEPKQNE------NRLSDTKPNDNKQNNGRSETTKSRPET 702
Query: 188 PREGEELKPE------DKDPRDPEESKE--PKEEKQRRRCKPKKPTRR-DASPESPSKK 237
P++ E +PE D P P++ + P+ KQ+ +P+ P ++ + PE+P +
Sbjct: 703 PKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHR 761
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 47.8 bits (112), Expect = 9e-06
Identities = 44/193 (22%), Positives = 81/193 (41%), Gaps = 13/193 (6%)
Query: 47 TSNARAQQRAAAQQRRSFLNAHHRSGAQVFPESPESESDHEHE-------EADLELSLPE 99
T R + R ++RR +R+ + + E E D E E E D
Sbjct: 88 TEKERDRDRKRDRERRRKEKETNRNRDR--EKQTEIERDREREKQKGRERERDRGRERER 145
Query: 100 CLEYEEEFDYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPK----HSTF 155
+ E+E + +TE + + + E+ET+ E + E E ETE + DR K +
Sbjct: 146 DRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDR 205
Query: 156 GQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRDPEESKEPKEEKQ 215
+ ++ + R D R +E Q R+ + + ++D ++ + + KE K+
Sbjct: 206 ERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKK 265
Query: 216 RRRCKPKKPTRRD 228
R+ K K+ RR+
Sbjct: 266 ERKEKKKEEKRRE 278
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 47.8 bits (112), Expect = 9e-06
Identities = 36/99 (36%), Positives = 46/99 (46%), Gaps = 10/99 (10%)
Query: 54 QRAAAQQRRSFLNAH-----HRSGAQVFPESPESESDHEHE-----EADLELSLPECLEY 103
+R A R+ FL+ H H S A P E E E E ++E E E
Sbjct: 42 RRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESES 101
Query: 104 EEEFDYETESETESEIESETDFETEPETAPTTEPETEPE 142
EEE + E ESETE E E E+D E+E ++ E E E E
Sbjct: 102 EEESESEEESETEEESEDESDEESEEDSEEEMEDEQESE 140
Score = 40.4 bits (93), Expect = 0.001
Identities = 26/87 (29%), Positives = 41/87 (47%)
Query: 59 QQRRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESE 118
Q+R A S ++ ES E E E + + E E E E + E+E+E +++
Sbjct: 87 QEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQ 146
Query: 119 IESETDFETEPETAPTTEPETEPEDDR 145
E E++ E E E +PE E E +R
Sbjct: 147 EEGESEAEGETEAESEFDPEIEMEAER 173
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 47.0 bits (110), Expect = 2e-05
Identities = 49/186 (26%), Positives = 72/186 (38%), Gaps = 35/186 (18%)
Query: 77 PESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIE----------SETDFE 126
P+ ESE E +E ++ LPE + EEE E E E E E S D
Sbjct: 1202 PKIQESEETVEPKE---DMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSS 1258
Query: 127 TEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQ--- 183
PET T EPE E E+++ P+ S + + L+ P+ A + Q
Sbjct: 1259 NSPET-ETKEPEVEEEEEK----PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDD 1313
Query: 184 -----EPQSPREGEELKPEDKDPRDPEESKEP---------KEEKQRRRCKPKKPTRRDA 229
E E + K ++ P + +EP +K R + K K+ T D+
Sbjct: 1314 HDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDS 1373
Query: 230 SPESPS 235
E PS
Sbjct: 1374 EEEQPS 1379
Score = 36.6 bits (83), Expect = 0.020
Identities = 35/169 (20%), Positives = 67/169 (39%), Gaps = 13/169 (7%)
Query: 82 SESDHEHEEADLELSLPECLEYEEEFDYETESETESEI----------ESETDFETEPET 131
S SDH + D S +E E +YE S +S + +S + +
Sbjct: 1537 SVSDHSQQVVDSGFSDLGSIESTTE-NYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSS 1595
Query: 132 APTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREG 191
+ T+ + S QS Q ++SP + PPS Q+ Q P
Sbjct: 1596 SSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPP 1655
Query: 192 EELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPI 240
+ +P+ P+ P+ + +P +Q+ + +P+ ++ P P ++ P+
Sbjct: 1656 PQ-QPQPPPPQ-PQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPL 1702
Score = 33.5 bits (75), Expect = 0.17
Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 10/93 (10%)
Query: 61 RRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEI- 119
+ SFL+A+ + + + E+E D E E+ + S+ E D+E +S T+ E+
Sbjct: 1348 QESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI 1407
Query: 120 ---------ESETDFETEPETAPTTEPETEPED 143
SE D ET T+ E+ +
Sbjct: 1408 ELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1440
Score = 28.9 bits (63), Expect = 4.3
Identities = 34/155 (21%), Positives = 62/155 (40%), Gaps = 13/155 (8%)
Query: 78 ESPESESDHEH-EEADLELSLPECLEYE--EEFDYETESETESEIESE-TDFETEPETAP 133
E+ E E++ +E +LE+S+ + + +E E+ Y ESE + E+ + + + P
Sbjct: 793 EAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLP 852
Query: 134 TTE-PETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGE 192
P RG K+ + + L L ++P + Q GE
Sbjct: 853 HDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAP--------QEQYGECGE 904
Query: 193 ELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRR 227
+ + + + EE EE+ + KP P RR
Sbjct: 905 KSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRR 939
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 47.0 bits (110), Expect = 2e-05
Identities = 49/186 (26%), Positives = 72/186 (38%), Gaps = 35/186 (18%)
Query: 77 PESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIE----------SETDFE 126
P+ ESE E +E ++ LPE + EEE E E E E E S D
Sbjct: 1202 PKIQESEETVEPKE---DMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSS 1258
Query: 127 TEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQ--- 183
PET T EPE E E+++ P+ S + + L+ P+ A + Q
Sbjct: 1259 NSPET-ETKEPEVEEEEEK----PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDD 1313
Query: 184 -----EPQSPREGEELKPEDKDPRDPEESKEP---------KEEKQRRRCKPKKPTRRDA 229
E E + K ++ P + +EP +K R + K K+ T D+
Sbjct: 1314 HDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDS 1373
Query: 230 SPESPS 235
E PS
Sbjct: 1374 EEEQPS 1379
Score = 36.6 bits (83), Expect = 0.020
Identities = 35/169 (20%), Positives = 67/169 (39%), Gaps = 13/169 (7%)
Query: 82 SESDHEHEEADLELSLPECLEYEEEFDYETESETESEI----------ESETDFETEPET 131
S SDH + D S +E E +YE S +S + +S + +
Sbjct: 1537 SVSDHSQQVVDSGFSDLGSIESTTE-NYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSS 1595
Query: 132 APTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREG 191
+ T+ + S QS Q ++SP + PPS Q+ Q P
Sbjct: 1596 SSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPP 1655
Query: 192 EELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPI 240
+ +P+ P+ P+ + +P +Q+ + +P+ ++ P P ++ P+
Sbjct: 1656 PQ-QPQPPPPQ-PQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPL 1702
Score = 33.5 bits (75), Expect = 0.17
Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 10/93 (10%)
Query: 61 RRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEI- 119
+ SFL+A+ + + + E+E D E E+ + S+ E D+E +S T+ E+
Sbjct: 1348 QESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI 1407
Query: 120 ---------ESETDFETEPETAPTTEPETEPED 143
SE D ET T+ E+ +
Sbjct: 1408 ELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1440
Score = 28.9 bits (63), Expect = 4.3
Identities = 34/155 (21%), Positives = 62/155 (40%), Gaps = 13/155 (8%)
Query: 78 ESPESESDHEH-EEADLELSLPECLEYE--EEFDYETESETESEIESE-TDFETEPETAP 133
E+ E E++ +E +LE+S+ + + +E E+ Y ESE + E+ + + + P
Sbjct: 793 EAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLP 852
Query: 134 TTE-PETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGE 192
P RG K+ + + L L ++P + Q GE
Sbjct: 853 HDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAP--------QEQYGECGE 904
Query: 193 ELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRR 227
+ + + + EE EE+ + KP P RR
Sbjct: 905 KSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRR 939
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 47.0 bits (110), Expect = 2e-05
Identities = 49/186 (26%), Positives = 72/186 (38%), Gaps = 35/186 (18%)
Query: 77 PESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIE----------SETDFE 126
P+ ESE E +E ++ LPE + EEE E E E E E S D
Sbjct: 1202 PKIQESEETVEPKE---DMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSS 1258
Query: 127 TEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQ--- 183
PET T EPE E E+++ P+ S + + L+ P+ A + Q
Sbjct: 1259 NSPET-ETKEPEVEEEEEK----PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDD 1313
Query: 184 -----EPQSPREGEELKPEDKDPRDPEESKEP---------KEEKQRRRCKPKKPTRRDA 229
E E + K ++ P + +EP +K R + K K+ T D+
Sbjct: 1314 HDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDS 1373
Query: 230 SPESPS 235
E PS
Sbjct: 1374 EEEQPS 1379
Score = 36.6 bits (83), Expect = 0.020
Identities = 35/169 (20%), Positives = 67/169 (39%), Gaps = 13/169 (7%)
Query: 82 SESDHEHEEADLELSLPECLEYEEEFDYETESETESEI----------ESETDFETEPET 131
S SDH + D S +E E +YE S +S + +S + +
Sbjct: 1537 SVSDHSQQVVDSGFSDLGSIESTTE-NYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSS 1595
Query: 132 APTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREG 191
+ T+ + S QS Q ++SP + PPS Q+ Q P
Sbjct: 1596 SSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPP 1655
Query: 192 EELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPI 240
+ +P+ P+ P+ + +P +Q+ + +P+ ++ P P ++ P+
Sbjct: 1656 PQ-QPQPPPPQ-PQPAPQPPPPQQQPQQQPQPQPQQPPPPPPPQQQPPL 1702
Score = 33.5 bits (75), Expect = 0.17
Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 10/93 (10%)
Query: 61 RRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEI- 119
+ SFL+A+ + + + E+E D E E+ + S+ E D+E +S T+ E+
Sbjct: 1348 QESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI 1407
Query: 120 ---------ESETDFETEPETAPTTEPETEPED 143
SE D ET T+ E+ +
Sbjct: 1408 ELKEEEEIPHSELDLETVQAVQSLTQEESSEHE 1440
Score = 28.9 bits (63), Expect = 4.3
Identities = 34/155 (21%), Positives = 62/155 (40%), Gaps = 13/155 (8%)
Query: 78 ESPESESDHEH-EEADLELSLPECLEYE--EEFDYETESETESEIESE-TDFETEPETAP 133
E+ E E++ +E +LE+S+ + + +E E+ Y ESE + E+ + + + P
Sbjct: 793 EAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVESEKKPEVMAPVSSTRLSKQVLP 852
Query: 134 TTE-PETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGE 192
P RG K+ + + L L ++P + Q GE
Sbjct: 853 HDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAP--------QEQYGECGE 904
Query: 193 ELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRR 227
+ + + + EE EE+ + KP P RR
Sbjct: 905 KSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRR 939
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 47.0 bits (110), Expect = 2e-05
Identities = 54/229 (23%), Positives = 83/229 (36%), Gaps = 34/229 (14%)
Query: 44 ALATSNARAQQRAAAQQRRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEY 103
++ TS A A + + + F ++ S + E + E EE + E+ E +
Sbjct: 1101 SIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMAS 1160
Query: 104 EEEFDYETESETES-----------EIESETDFETE---PETAPTTEPET-------EPE 142
D+E + E + +E E D ETE PE P+ E EP
Sbjct: 1161 AGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPA 1220
Query: 143 DDRGPVVPKHSTFGQS----LTQRLHALKLRS-PDASPSRAPPSTQEPQS------PREG 191
D R P P+ Q L+ A ++ + P SP RAP E + P
Sbjct: 1221 DSREP--PEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPL 1278
Query: 192 EELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPI 240
+ P + PR P EP+ P +P D P +P G +
Sbjct: 1279 QPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSL 1327
Score = 38.5 bits (88), Expect = 0.005
Identities = 34/145 (23%), Positives = 60/145 (41%), Gaps = 12/145 (8%)
Query: 72 GAQVFPESP-ESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPE 130
G + P P E +S E +E + E E EEE + E E E + + +S+ E+E +
Sbjct: 1018 GVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESEND 1077
Query: 131 TAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPRE 190
T E +D+ G S + ++ +A+ S + E +S E
Sbjct: 1078 DEDTALSEASEKDE-----------GDSDEEETVSIVTSKAEATSSSESSESSEFESSSE 1126
Query: 191 GEELKPEDKDPRDPEESKEPKEEKQ 215
ED++ E +E +EE++
Sbjct: 1127 SSPSSSEDEEEVVAREEEEEEEEEE 1151
Score = 34.7 bits (78), Expect = 0.078
Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 16/141 (11%)
Query: 79 SPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETE--PETAPTTE 136
S E ES E EEA E EEE + + + +++ ESE D E E + E
Sbjct: 1042 SEEQESTEEEEEA----------EEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDE 1091
Query: 137 PETEPEDDRGPVVPK---HSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEE 193
+++ E+ V K S+ S + + SP +S +E + E EE
Sbjct: 1092 GDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEE 1151
Query: 194 LKPEDK-DPRDPEESKEPKEE 213
+ E+ PE+ ++ EE
Sbjct: 1152 MVAEESMASAGPEDFEQDGEE 1172
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 46.6 bits (109), Expect = 2e-05
Identities = 42/171 (24%), Positives = 69/171 (40%), Gaps = 17/171 (9%)
Query: 78 ESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIE---SETDFETEPETAPT 134
E PE E+ +H++ E + E+E + E + +++ S T+ +T PE
Sbjct: 184 EKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTD 243
Query: 135 TEPETEPEDDRGPVVPKHSTFGQSLTQRLHAL---KLRS---PDASPSRAPPSTQEPQ-- 186
+ + + + T S R+ A K RS P P+ + P EP+
Sbjct: 244 GDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEE 303
Query: 187 ------SPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASP 231
SP E EE + E+++ EE +E E Q + KP P D P
Sbjct: 304 QPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMP 354
Score = 30.8 bits (68), Expect = 1.1
Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 77 PESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTE 136
P +P+ E E+ + S E E EEE + E E E E +SE E +P E
Sbjct: 292 PSAPDLTEPKE-EQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEE 350
Query: 137 PETEPEDDR 145
+ P D++
Sbjct: 351 DKMPPYDEQ 359
>gi|30795231 brain abundant, membrane attached signal protein 1
[Homo sapiens]
Length = 227
Score = 46.2 bits (108), Expect = 3e-05
Identities = 43/158 (27%), Positives = 65/158 (41%), Gaps = 6/158 (3%)
Query: 81 ESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEPE-T 139
E E + E E E +E+ D + E + E E E E D E AP EPE T
Sbjct: 32 EEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAE-EKEGEKDAAAAKEEAPKAEPEKT 90
Query: 140 EPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKPEDK 199
E + PK Q+ A +P A+ + A P+ E +P GEE E+
Sbjct: 91 EGAAEAKAEPPKAPEQEQAAPGP--AAGGEAPKAAEAAAAPA--ESAAPAAGEEPSKEEG 146
Query: 200 DPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKK 237
+P+ E P ++ + P ++ +S +PS K
Sbjct: 147 EPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSK 184
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 46.2 bits (108), Expect = 3e-05
Identities = 38/138 (27%), Positives = 60/138 (43%), Gaps = 10/138 (7%)
Query: 78 ESPESESDHEHEEADLELSLPECLEYEEEFDYETESET-ESEIESETDFETEPETAPTTE 136
E+ ES + E E + + EY EE +ESET E E ESET E E + P +E
Sbjct: 1595 EATESTVESEEESSS------DYTEYSEEESEFSESETTEEESESETPSEEEESSTPESE 1648
Query: 137 PETEPEDDRGPVVPKHSTFG--QSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEEL 194
E+E + G K+ + + + + +K R + + P +E + E E
Sbjct: 1649 -ESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQEEQKEPKMEEEEHSEEEESG 1707
Query: 195 KPEDKDPRDPEESKEPKE 212
++ DPE P+E
Sbjct: 1708 PAPVEESTDPEAQDIPEE 1725
Score = 40.0 bits (92), Expect = 0.002
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 5/141 (3%)
Query: 105 EEFDYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLH 164
EE+ E E + ++ D E E+ T E E E D + S F +S T
Sbjct: 1573 EEWQRRLEEEDKDYLKLTLDQEEATES--TVESEEESSSDYTEYSEEESEFSESETTEEE 1630
Query: 165 ALKLRSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRDP---EESKEPKEEKQRRRCKP 221
+ + S P S + + EGE+ + R EE KE K K+ + +
Sbjct: 1631 SESETPSEEEESSTPESEESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQEEQ 1690
Query: 222 KKPTRRDASPESPSKKGPIPI 242
K+P + + GP P+
Sbjct: 1691 KEPKMEEEEHSEEEESGPAPV 1711
Score = 38.1 bits (87), Expect = 0.007
Identities = 36/137 (26%), Positives = 57/137 (41%), Gaps = 3/137 (2%)
Query: 78 ESPESESDHEHEEAD-LELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTE 136
E E + E E+ D L+L+L + E E E+E E+ S+ ++ E+E + TTE
Sbjct: 1571 EGEEWQRRLEEEDKDYLKLTLDQ--EEATESTVESEEESSSDYTEYSEEESEFSESETTE 1628
Query: 137 PETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKP 196
E+E E +S + K R R P + + EE +
Sbjct: 1629 EESESETPSEEEESSTPESEESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQE 1688
Query: 197 EDKDPRDPEESKEPKEE 213
E K+P+ EE +EE
Sbjct: 1689 EQKEPKMEEEEHSEEEE 1705
Score = 28.5 bits (62), Expect = 5.6
Identities = 19/85 (22%), Positives = 34/85 (40%), Gaps = 5/85 (5%)
Query: 129 PETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSP 188
P AP P P P P + + +H ++ + PP+ QE
Sbjct: 1439 PAPAPVAAPPPPP-----PPPPGAHLYEELGDSSMHKYEMPQYGSRRRLLPPAGQEEYGE 1493
Query: 189 REGEELKPEDKDPRDPEESKEPKEE 213
GE + +++ +P++ K+PK E
Sbjct: 1494 VVGEAEEEYEEEEEEPKKIKKPKVE 1518
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 46.2 bits (108), Expect = 3e-05
Identities = 52/216 (24%), Positives = 86/216 (39%), Gaps = 18/216 (8%)
Query: 40 ALLRALATSNARAQQRAAAQQRRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPE 99
A+ LA S + +++ AA+++ A A +SP + E +E + E E
Sbjct: 475 AITEELAVS-MKEEKKEAAEEKEEEPEAEEEEVAA--KKSPVKATAPEVKEEEGEKEEEE 531
Query: 100 CLEYEEEFDYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSL 159
E EEE D +S+ E SE + +E E E ETE E + K +
Sbjct: 532 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 591
Query: 160 TQRLHA-------LKLRSPDASPSRAPPSTQE-------PQSPREGEELKPEDKDP-RDP 204
++ + K+ P+ + S P S E P+SP E + P K P +
Sbjct: 592 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 651
Query: 205 EESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPI 240
+S PK + + P + + +SP K P+
Sbjct: 652 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 687
Score = 40.8 bits (94), Expect = 0.001
Identities = 45/182 (24%), Positives = 75/182 (41%), Gaps = 23/182 (12%)
Query: 78 ESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEP 137
E E E + EA+ E E E ++ + E T+ E+ ++ E +PE A + P
Sbjct: 560 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVE-KPEKAKSPVP 618
Query: 138 ETEPEDDRGPVVPKHSTF--GQS------LTQRLHALKLRSPDASPSRAPPSTQE----- 184
++ E+ VPK G+S + ++ + +SP ++P S
Sbjct: 619 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 678
Query: 185 ----PQSPRE-----GEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPS 235
P+SP E E K E K+ + E + PKEEK ++ + K ESP
Sbjct: 679 KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 738
Query: 236 KK 237
K+
Sbjct: 739 KE 740
Score = 38.9 bits (89), Expect = 0.004
Identities = 38/179 (21%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 65 LNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETD 124
L H+ ++ E+ + E EEA ++ + +EE E + E E +
Sbjct: 446 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 505
Query: 125 FETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRL-HALKLRSPDASPSRAPPSTQ 183
+ T PE + E+ K GQ + K + S S++
Sbjct: 506 VAAKKSPVKATAPEVKEEEGE-----KEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE 560
Query: 184 EPQSPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSK-KGPIP 241
+ + +E E + E + + E +E K E++ K+ DA E P K K P+P
Sbjct: 561 KEEGEQEEGETEAE-AEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 618
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 46.2 bits (108), Expect = 3e-05
Identities = 52/216 (24%), Positives = 86/216 (39%), Gaps = 18/216 (8%)
Query: 40 ALLRALATSNARAQQRAAAQQRRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPE 99
A+ LA S + +++ AA+++ A A +SP + E +E + E E
Sbjct: 99 AITEELAVS-MKEEKKEAAEEKEEEPEAEEEEVAA--KKSPVKATAPEVKEEEGEKEEEE 155
Query: 100 CLEYEEEFDYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSL 159
E EEE D +S+ E SE + +E E E ETE E + K +
Sbjct: 156 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 215
Query: 160 TQRLHA-------LKLRSPDASPSRAPPSTQE-------PQSPREGEELKPEDKDP-RDP 204
++ + K+ P+ + S P S E P+SP E + P K P +
Sbjct: 216 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 275
Query: 205 EESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPI 240
+S PK + + P + + +SP K P+
Sbjct: 276 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 311
Score = 40.8 bits (94), Expect = 0.001
Identities = 45/182 (24%), Positives = 75/182 (41%), Gaps = 23/182 (12%)
Query: 78 ESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEP 137
E E E + EA+ E E E ++ + E T+ E+ ++ E +PE A + P
Sbjct: 184 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVE-KPEKAKSPVP 242
Query: 138 ETEPEDDRGPVVPKHSTF--GQS------LTQRLHALKLRSPDASPSRAPPSTQE----- 184
++ E+ VPK G+S + ++ + +SP ++P S
Sbjct: 243 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 302
Query: 185 ----PQSPRE-----GEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPS 235
P+SP E E K E K+ + E + PKEEK ++ + K ESP
Sbjct: 303 KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 362
Query: 236 KK 237
K+
Sbjct: 363 KE 364
Score = 38.9 bits (89), Expect = 0.004
Identities = 38/179 (21%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 65 LNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETD 124
L H+ ++ E+ + E EEA ++ + +EE E + E E +
Sbjct: 70 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 129
Query: 125 FETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRL-HALKLRSPDASPSRAPPSTQ 183
+ T PE + E+ K GQ + K + S S++
Sbjct: 130 VAAKKSPVKATAPEVKEEEGE-----KEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE 184
Query: 184 EPQSPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSK-KGPIP 241
+ + +E E + E + + E +E K E++ K+ DA E P K K P+P
Sbjct: 185 KEEGEQEEGETEAE-AEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 242
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 46.2 bits (108), Expect = 3e-05
Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 23/168 (13%)
Query: 59 QQRRSFLNAHHRSGAQVFPESPESESDHEHEEADLE--LSLPECLEYEEEFDYETESETE 116
+ R S+ + H S +SP + D E E DLE L E E EEE + E E E
Sbjct: 384 RDRDSYHSCH--SSVSYHKDSPRWDQDEEELEEDLEDFLEEEELPEDEEELE-EEEEEVP 440
Query: 117 SEIESETDFETEPETAP------TTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRS 170
++ S E P + P ++D+ PV P T+ K+
Sbjct: 441 DDLGSYAQREDVAVAEPKDFKRISLPPAAPGKEDKAPVAP---------TEAPDMAKVAP 491
Query: 171 PDASPSRAPPSTQEPQSPREGEELKPEDKDPRDPEESKEPKEEKQRRR 218
A+P + P + Q P++ +E E PR+ EE +E ++ R +
Sbjct: 492 KPATPDKVPAAEQIPEAEPPKDE---ESFRPREDEEGQEGQDSMSRAK 536
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 45.4 bits (106), Expect = 4e-05
Identities = 45/164 (27%), Positives = 61/164 (37%), Gaps = 38/164 (23%)
Query: 97 LPECLEYEEEFDYETESETES-EIE----------SETDFETEPETAPTTEPETEPEDDR 145
L E E +FD E + + S E+E S + T P ++P T P P
Sbjct: 999 LGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISE 1058
Query: 146 GPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKP-EDKDPRDP 204
GPV +L +R P +PSR P SP + + P KDP P
Sbjct: 1059 GPV---------------PSLPIR-PSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQP 1102
Query: 205 EESKEPKEEKQRRRCKPKKPTRRDASPESP----SKKGPIPIRR 244
E K P +P P R A P+ P + P P R+
Sbjct: 1103 LEPKRPPPP------RPVAPPTRPAPPQRPPPPSGARSPAPTRK 1140
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 45.4 bits (106), Expect = 4e-05
Identities = 45/164 (27%), Positives = 61/164 (37%), Gaps = 38/164 (23%)
Query: 97 LPECLEYEEEFDYETESETES-EIE----------SETDFETEPETAPTTEPETEPEDDR 145
L E E +FD E + + S E+E S + T P ++P T P P
Sbjct: 1038 LGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISE 1097
Query: 146 GPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKP-EDKDPRDP 204
GPV +L +R P +PSR P SP + + P KDP P
Sbjct: 1098 GPV---------------PSLPIR-PSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQP 1141
Query: 205 EESKEPKEEKQRRRCKPKKPTRRDASPESP----SKKGPIPIRR 244
E K P +P P R A P+ P + P P R+
Sbjct: 1142 LEPKRPPPP------RPVAPPTRPAPPQRPPPPSGARSPAPTRK 1179
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 45.4 bits (106), Expect = 4e-05
Identities = 45/164 (27%), Positives = 61/164 (37%), Gaps = 38/164 (23%)
Query: 97 LPECLEYEEEFDYETESETES-EIE----------SETDFETEPETAPTTEPETEPEDDR 145
L E E +FD E + + S E+E S + T P ++P T P P
Sbjct: 1038 LGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISE 1097
Query: 146 GPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKP-EDKDPRDP 204
GPV +L +R P +PSR P SP + + P KDP P
Sbjct: 1098 GPV---------------PSLPIR-PSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQP 1141
Query: 205 EESKEPKEEKQRRRCKPKKPTRRDASPESP----SKKGPIPIRR 244
E K P +P P R A P+ P + P P R+
Sbjct: 1142 LEPKRPPPP------RPVAPPTRPAPPQRPPPPSGARSPAPTRK 1179
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 45.4 bits (106), Expect = 4e-05
Identities = 55/229 (24%), Positives = 89/229 (38%), Gaps = 53/229 (23%)
Query: 51 RAQQRAAAQQRRSFLNAHHRSGAQVF------------PESPESE-----------SDHE 87
RA++R ++ R ++AHHR+ + + P P E + +
Sbjct: 186 RAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 245
Query: 88 HEEADLELSLPECLEYE------EEFDYETESETESEIESETDFETEPETAPTTEPETEP 141
EE DL L + + E E E+ S +E E E E + E E T+ +E E E
Sbjct: 246 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 305
Query: 142 EDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEE------LK 195
E++ +S +AS A ++E S E E +
Sbjct: 306 EEEEEEETGSNSE-----------------EASEQSAEEVSEEEMSEDEERENENHLLVV 348
Query: 196 PEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPIPIRR 244
PE + RD ES+E +EE + T D P+SP+ PI +++
Sbjct: 349 PESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPA-LSPIELKQ 396
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 45.4 bits (106), Expect = 4e-05
Identities = 55/229 (24%), Positives = 89/229 (38%), Gaps = 53/229 (23%)
Query: 51 RAQQRAAAQQRRSFLNAHHRSGAQVF------------PESPESE-----------SDHE 87
RA++R ++ R ++AHHR+ + + P P E + +
Sbjct: 195 RAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 254
Query: 88 HEEADLELSLPECLEYE------EEFDYETESETESEIESETDFETEPETAPTTEPETEP 141
EE DL L + + E E E+ S +E E E E + E E T+ +E E E
Sbjct: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 314
Query: 142 EDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEE------LK 195
E++ +S +AS A ++E S E E +
Sbjct: 315 EEEEEEETGSNSE-----------------EASEQSAEEVSEEEMSEDEERENENHLLVV 357
Query: 196 PEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPIPIRR 244
PE + RD ES+E +EE + T D P+SP+ PI +++
Sbjct: 358 PESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPA-LSPIELKQ 405
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 45.4 bits (106), Expect = 4e-05
Identities = 55/229 (24%), Positives = 89/229 (38%), Gaps = 53/229 (23%)
Query: 51 RAQQRAAAQQRRSFLNAHHRSGAQVF------------PESPESE-----------SDHE 87
RA++R ++ R ++AHHR+ + + P P E + +
Sbjct: 163 RAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 222
Query: 88 HEEADLELSLPECLEYE------EEFDYETESETESEIESETDFETEPETAPTTEPETEP 141
EE DL L + + E E E+ S +E E E E + E E T+ +E E E
Sbjct: 223 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 282
Query: 142 EDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEE------LK 195
E++ +S +AS A ++E S E E +
Sbjct: 283 EEEEEEETGSNSE-----------------EASEQSAEEVSEEEMSEDEERENENHLLVV 325
Query: 196 PEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPIPIRR 244
PE + RD ES+E +EE + T D P+SP+ PI +++
Sbjct: 326 PESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPA-LSPIELKQ 373
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 45.4 bits (106), Expect = 4e-05
Identities = 55/229 (24%), Positives = 89/229 (38%), Gaps = 53/229 (23%)
Query: 51 RAQQRAAAQQRRSFLNAHHRSGAQVF------------PESPESE-----------SDHE 87
RA++R ++ R ++AHHR+ + + P P E + +
Sbjct: 152 RAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 211
Query: 88 HEEADLELSLPECLEYE------EEFDYETESETESEIESETDFETEPETAPTTEPETEP 141
EE DL L + + E E E+ S +E E E E + E E T+ +E E E
Sbjct: 212 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 271
Query: 142 EDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEE------LK 195
E++ +S +AS A ++E S E E +
Sbjct: 272 EEEEEEETGSNSE-----------------EASEQSAEEVSEEEMSEDEERENENHLLVV 314
Query: 196 PEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPIPIRR 244
PE + RD ES+E +EE + T D P+SP+ PI +++
Sbjct: 315 PESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPA-LSPIELKQ 362
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 45.4 bits (106), Expect = 4e-05
Identities = 55/229 (24%), Positives = 89/229 (38%), Gaps = 53/229 (23%)
Query: 51 RAQQRAAAQQRRSFLNAHHRSGAQVF------------PESPESE-----------SDHE 87
RA++R ++ R ++AHHR+ + + P P E + +
Sbjct: 197 RAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 256
Query: 88 HEEADLELSLPECLEYE------EEFDYETESETESEIESETDFETEPETAPTTEPETEP 141
EE DL L + + E E E+ S +E E E E + E E T+ +E E E
Sbjct: 257 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 316
Query: 142 EDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEE------LK 195
E++ +S +AS A ++E S E E +
Sbjct: 317 EEEEEEETGSNSE-----------------EASEQSAEEVSEEEMSEDEERENENHLLVV 359
Query: 196 PEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPIPIRR 244
PE + RD ES+E +EE + T D P+SP+ PI +++
Sbjct: 360 PESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPA-LSPIELKQ 407
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 45.1 bits (105), Expect = 6e-05
Identities = 53/220 (24%), Positives = 84/220 (38%), Gaps = 52/220 (23%)
Query: 51 RAQQRAAAQQRRSFLNAHHRSGAQVF------------PESPESE-----------SDHE 87
RA++R ++ R ++AHHR+ + + P P E + +
Sbjct: 185 RAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 244
Query: 88 HEEADLELSLPECLEYE------EEFDYETESETESEIESETDFETEPETAPTTEPETEP 141
EE DL L + + E E E+ S +E E E E + E E T+ +E E E
Sbjct: 245 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 304
Query: 142 EDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEE------LK 195
E++ +S +AS A ++E S E E +
Sbjct: 305 EEEEEEETGSNSE-----------------EASEQSAEEVSEEEMSEDEERENENHLLVV 347
Query: 196 PEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPS 235
PE + RD ES+E +EE + T D P+SP+
Sbjct: 348 PESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPA 387
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 45.1 bits (105), Expect = 6e-05
Identities = 53/220 (24%), Positives = 84/220 (38%), Gaps = 52/220 (23%)
Query: 51 RAQQRAAAQQRRSFLNAHHRSGAQVF------------PESPESE-----------SDHE 87
RA++R ++ R ++AHHR+ + + P P E + +
Sbjct: 195 RAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 254
Query: 88 HEEADLELSLPECLEYE------EEFDYETESETESEIESETDFETEPETAPTTEPETEP 141
EE DL L + + E E E+ S +E E E E + E E T+ +E E E
Sbjct: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 314
Query: 142 EDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEE------LK 195
E++ +S +AS A ++E S E E +
Sbjct: 315 EEEEEEETGSNSE-----------------EASEQSAEEVSEEEMSEDEERENENHLLVV 357
Query: 196 PEDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPS 235
PE + RD ES+E +EE + T D P+SP+
Sbjct: 358 PESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPA 397
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 44.7 bits (104), Expect = 7e-05
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 12/175 (6%)
Query: 78 ESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIE---SETDFETEPETAPT 134
E PE E+ +H++ E + E+E + E + +++ S T+ +T PE
Sbjct: 184 EKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTD 243
Query: 135 TEPETEPEDDRGPVVPKHSTFGQSLTQRLHAL---KLRSPDASPSRAP-PSTQEPQSPRE 190
+ + + + T S R+ A K RS +A P+ P PS + P+E
Sbjct: 244 GDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRS-EALPTDLPAPSAPDLTEPKE 302
Query: 191 GEELKP----EDKDPRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKKGPIP 241
+ P E+++ + EE +E +EE++ + P P SP+++ +P
Sbjct: 303 EQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMP 357
Score = 35.0 bits (79), Expect = 0.059
Identities = 38/147 (25%), Positives = 55/147 (37%), Gaps = 38/147 (25%)
Query: 96 SLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTF 155
S P+ E +EE S TE E E E + E E E E E E+D
Sbjct: 293 SAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAE-------EEEEEED----------- 334
Query: 156 GQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKPEDKDPR---DPEESKEPKE 212
S +A P +PP +P SP E +++ P D+ + D + K
Sbjct: 335 --------------SEEAPPPLSPP---QPASPAEEDKMPPYDEQTQAFIDAAQEARNKF 377
Query: 213 EKQRRRCKPKKPTRRDASPESPSKKGP 239
E+ R K + + R+ E GP
Sbjct: 378 EEAERSLKDMEESIRNLEQEISFDFGP 404
Score = 32.0 bits (71), Expect = 0.50
Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 5/71 (7%)
Query: 77 PESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTE 136
P +P+ E + +P EEE + E E E E E E D E P +
Sbjct: 292 PSAPDLTEPKEEQPP-----VPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQ 346
Query: 137 PETEPEDDRGP 147
P + E+D+ P
Sbjct: 347 PASPAEEDKMP 357
Score = 28.9 bits (63), Expect = 4.3
Identities = 19/69 (27%), Positives = 27/69 (39%), Gaps = 11/69 (15%)
Query: 77 PESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTE 136
P P S ++ E EE E EEE + E E E E E+ +P E
Sbjct: 305 PPVPSSPTEEEEEE-----------EEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEE 353
Query: 137 PETEPEDDR 145
+ P D++
Sbjct: 354 DKMPPYDEQ 362
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 44.3 bits (103), Expect = 1e-04
Identities = 40/140 (28%), Positives = 61/140 (43%), Gaps = 13/140 (9%)
Query: 78 ESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEP 137
E E E + E EE + E E E EEE+ E E E E E E +FE E E
Sbjct: 891 EEEEEEEEEEEEEEEEEEDFEEEEEDEEEY---FEEEEEEEEEFEEEFEEEEGELEEEEE 947
Query: 138 ETEPEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKPE 197
E + E++ + FG + ++ P PP+ P+SP +++PE
Sbjct: 948 EEDEEEEEELEEVEDLEFGTA------GGEVEEGAPPPPTLPPALPPPESP---PKVQPE 998
Query: 198 -DKDPRDPEESKEPKEEKQR 216
+ +P E +EP E++R
Sbjct: 999 PEPEPGLLLEVEEPGTEEER 1018
Score = 42.7 bits (99), Expect = 3e-04
Identities = 49/191 (25%), Positives = 64/191 (33%), Gaps = 59/191 (30%)
Query: 78 ESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETE--------- 128
E E E D E EE D E E E EEEF+ E E E E E+E E + E E
Sbjct: 902 EEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE-EGELEEEEEEEDEEEEEELEEV 960
Query: 129 ----------------------------PETAPTTEPETEPED----------------- 143
PE+ P +PE EPE
Sbjct: 961 EDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGA 1020
Query: 144 DRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRD 203
D P + + Q +R + SP A P +EP +P E + ED +
Sbjct: 1021 DTAPTLAPEALPSQGEVER----EGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKV 1076
Query: 204 PEESKEPKEEK 214
+ P EE+
Sbjct: 1077 QPPPETPAEEE 1087
Score = 30.8 bits (68), Expect = 1.1
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 77 PESPESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESE------TDFETEPE 130
P +P + + E E+ ++ P EEE + ETE+E E E + DF P
Sbjct: 1058 PSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPP 1117
Query: 131 TAPTTEPETEPE 142
P TEP+
Sbjct: 1118 DDEKPPPPTEPD 1129
Score = 30.4 bits (67), Expect = 1.5
Identities = 44/165 (26%), Positives = 61/165 (36%), Gaps = 41/165 (24%)
Query: 78 ESPESESDHEHEEA-----DLEL---------------SLPECL---EYEEEFDYETESE 114
E E E D E EE DLE +LP L E + E E E
Sbjct: 943 EEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPE 1002
Query: 115 TESEIESE---TDFETEPETAPTTEPETEP---EDDRGPVVPKHSTFGQSLTQRLHALKL 168
+E E T+ E +TAPT PE P E +R P Q L +
Sbjct: 1003 PGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEE------ 1056
Query: 169 RSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRDPEESKEPKEE 213
PS APP+ E ++ ++++P + P + E E + E
Sbjct: 1057 -----EPS-APPTLLEEETEDGSDKVQPPPETPAEEEMETETEAE 1095
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 43.9 bits (102), Expect = 1e-04
Identities = 52/207 (25%), Positives = 86/207 (41%), Gaps = 29/207 (14%)
Query: 53 QQRAAAQQRRSFLNAHHRSGAQVFPESPESESDHEHEEADLELSLPECLE-YEEEFD--- 108
++ AA Q+R R + + + E E + E A L E LE Y+++ D
Sbjct: 452 EKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPK 511
Query: 109 YETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQSLTQRLHALKL 168
Y S + + + + E E + + E E+ R ++ + + QR+
Sbjct: 512 YYRGSALQKRLR-DREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQ--- 567
Query: 169 RSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKPTRR- 227
+A R P QEP+S E EE K E ++ R EE E +EE +++ C KPT R
Sbjct: 568 ---EAERRRQPQIKQEPESEEEEEE-KQEKEEKR--EEPMEEEEEPEQKPC--LKPTLRP 619
Query: 228 ------------DASPESPSKKGPIPI 242
+A+P +P + P I
Sbjct: 620 ISSAPSVSSASGNATPNTPGDESPCGI 646
Score = 35.8 bits (81), Expect = 0.035
Identities = 32/157 (20%), Positives = 62/157 (39%), Gaps = 25/157 (15%)
Query: 81 ESESDHEHEEADLELSLPECLEYEEEFDYETESETESEIESETDFETEPETAPTTEPETE 140
E E + E E + E E E+E + E E E + + + + + + + + + E
Sbjct: 313 ERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRE 372
Query: 141 PEDDRGPVVPKHSTFGQSLTQRLHALKLRSPDASPSRAPPSTQEPQSPREGEELKPEDKD 200
D R+ D S SR +E + RE E + +++
Sbjct: 373 RSSD------------------------RNKDRSRSREKSRDRERERERERERERERERE 408
Query: 201 PRDPEESKEPKEEKQRRRCKPKKPTRRDASPESPSKK 237
R+ E +E + E++R R K KK R + ++ ++
Sbjct: 409 -REREREREREREREREREKDKKRDREEDEEDAYERR 444
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.125 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,131,231
Number of Sequences: 37866
Number of extensions: 681400
Number of successful extensions: 10545
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 368
Number of HSP's successfully gapped in prelim test: 903
Number of HSP's that attempted gapping in prelim test: 6034
Number of HSP's gapped (non-prelim): 3953
length of query: 245
length of database: 18,247,518
effective HSP length: 100
effective length of query: 145
effective length of database: 14,460,918
effective search space: 2096833110
effective search space used: 2096833110
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.