Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 7705961
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7705961 claudin 18 isoform 1 [Homo sapiens]
(261 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 527 e-150
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 491 e-139
gi|183979973 claudin 19 isoform a [Homo sapiens] 146 2e-35
gi|183979975 claudin 19 isoform b [Homo sapiens] 144 8e-35
gi|153792186 claudin 7 [Homo sapiens] 140 9e-34
gi|10863887 claudin 1 [Homo sapiens] 139 3e-33
gi|33598916 claudin 10 isoform a [Homo sapiens] 135 4e-32
gi|5921465 claudin 10 isoform b [Homo sapiens] 135 5e-32
gi|4502875 claudin 3 [Homo sapiens] 129 3e-30
gi|4502877 claudin 4 [Homo sapiens] 125 5e-29
gi|153792768 claudin 6 [Homo sapiens] 123 1e-28
gi|225703142 claudin 14 [Homo sapiens] 122 4e-28
gi|21536294 claudin 14 [Homo sapiens] 122 4e-28
gi|225703138 claudin 14 [Homo sapiens] 122 4e-28
gi|6912314 claudin 14 [Homo sapiens] 122 4e-28
gi|225703140 claudin 14 [Homo sapiens] 122 4e-28
gi|195947374 claudin 5 [Homo sapiens] 118 6e-27
gi|195947372 claudin 5 [Homo sapiens] 118 6e-27
gi|7656981 claudin 15 [Homo sapiens] 115 5e-26
gi|40788011 claudin 8 [Homo sapiens] 113 1e-25
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 112 3e-25
gi|11141861 claudin 9 [Homo sapiens] 112 4e-25
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 111 6e-25
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 111 6e-25
gi|6912316 claudin 17 [Homo sapiens] 111 6e-25
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 110 1e-24
gi|162417973 claudin 22 [Homo sapiens] 107 1e-23
gi|47716519 claudin 20 [Homo sapiens] 105 3e-23
gi|9966781 claudin 2 [Homo sapiens] 102 3e-22
gi|10938016 claudin 11 [Homo sapiens] 95 5e-20
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 527 bits (1357), Expect = e-150
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGF 60
MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGF
Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGF 60
Query: 61 TECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLT 120
TECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLT
Sbjct: 61 TECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLT 120
Query: 121 SGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWV 180
SGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWV
Sbjct: 121 SGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWV 180
Query: 181 AGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKI 240
AGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKI
Sbjct: 181 AGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKI 240
Query: 241 YDGGARTEDEVQSYPSKHDYV 261
YDGGARTEDEVQSYPSKHDYV
Sbjct: 241 YDGGARTEDEVQSYPSKHDYV 261
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 491 bits (1264), Expect = e-139
Identities = 240/261 (91%), Positives = 252/261 (96%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGF 60
M+ T CQ + F++S++G+AG IAAT MD WSTQDLY+NPVT+VF Y+GLWRSCVR+SSGF
Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGF 60
Query: 61 TECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLT 120
TECR YFT+LGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLT
Sbjct: 61 TECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLT 120
Query: 121 SGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWV 180
SGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWV
Sbjct: 121 SGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWV 180
Query: 181 AGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKI 240
AGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKI
Sbjct: 181 AGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKI 240
Query: 241 YDGGARTEDEVQSYPSKHDYV 261
YDGGARTEDEVQSYPSKHDYV
Sbjct: 241 YDGGARTEDEVQSYPSKHDYV 261
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 146 bits (369), Expect = 2e-35
Identities = 76/224 (33%), Positives = 121/224 (54%), Gaps = 16/224 (7%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLY--DNPVTSVFQYEGLWRSCVRQSS 58
M+ + Q++ + L++ G G IA+T + W Q Y D +T+V YEGLW SC QS+
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWK-QSSYAGDAIITAVGLYEGLWMSCASQST 59
Query: 59 GFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMT 118
G +C+ Y ++L L +Q+ RALM+V ++LG + +++S+ +KC R+G AK +
Sbjct: 60 GQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVA 119
Query: 119 LTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVG 178
+ G +FI++GLC + VS +A ++ F+ + V RY FG ALFVG
Sbjct: 120 IAGGALFILAGLCTLTAVSWYATLVTQEFFNPST-----------PVNARYEFGPALFVG 168
Query: 179 WVAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKP 222
W + GL ++GG +C C PE N Y + A +P
Sbjct: 169 WASAGLAVLGGSFLCCTCP--EPERPNSSPQPYRPGPSAAAREP 210
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 144 bits (363), Expect = 8e-35
Identities = 75/221 (33%), Positives = 119/221 (53%), Gaps = 16/221 (7%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLY--DNPVTSVFQYEGLWRSCVRQSS 58
M+ + Q++ + L++ G G IA+T + W Q Y D +T+V YEGLW SC QS+
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWK-QSSYAGDAIITAVGLYEGLWMSCASQST 59
Query: 59 GFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMT 118
G +C+ Y ++L L +Q+ RALM+V ++LG + +++S+ +KC R+G AK +
Sbjct: 60 GQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVA 119
Query: 119 LTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVG 178
+ G +FI++GLC + VS +A ++ F+ + V RY FG ALFVG
Sbjct: 120 IAGGALFILAGLCTLTAVSWYATLVTQEFFNPST-----------PVNARYEFGPALFVG 168
Query: 179 WVAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVA 219
W + GL ++GG +C C PE N Y + A
Sbjct: 169 WASAGLAVLGGSFLCCTCP--EPERPNSSPQPYRPGPSAAA 207
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 140 bits (354), Expect = 9e-34
Identities = 74/221 (33%), Positives = 118/221 (53%), Gaps = 12/221 (5%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLY-DNPVTSVFQYEGLWRSCVRQSSG 59
M+ + Q++ F +++LG G +A T + W DN +T+ Y+GLW CV QS+G
Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
C+ Y ++L L A LQA RALM+V +VLG + + V+ +KC R G + KA + +
Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
GI+FIV+GL A+ S + + +VT+F+ ++ T +Y FG A+F+GW
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFY----------NPLIPT-NIKYEFGPAIFIGW 169
Query: 180 VAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAY 220
L ++GG ++ +C G + SY S S Y
Sbjct: 170 AGSALVILGGALLSCSCPGNESKAGYRVPRSYPKSNSSKEY 210
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 139 bits (349), Expect = 3e-33
Identities = 70/197 (35%), Positives = 109/197 (55%), Gaps = 12/197 (6%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLY-DNPVTSVFQYEGLWRSCVRQSSG 59
M+ Q++ F+L+ LG G I +T + W DN VT+ YEGLW SCV QS+G
Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
+C+ + ++L L + LQA RALM+VGI+LG I + V+ +KC++ ++ K M +
Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
G +F+++GL + + + N +V F+ + V RY FG ALF GW
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFY-----------DPMTPVNARYEFGQALFTGW 169
Query: 180 VAGGLTLIGGVMMCIAC 196
A L L+GG ++C +C
Sbjct: 170 AAASLCLLGGALLCCSC 186
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 135 bits (340), Expect = 4e-32
Identities = 82/251 (32%), Positives = 124/251 (49%), Gaps = 37/251 (14%)
Query: 7 QVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTECRPY 66
Q+ A + + G +AAT + W + +T+ + Y+GLW +C + G CRP+
Sbjct: 5 QIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCRPH 64
Query: 67 FTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFI 126
FTI + +QA R LMI + LG G + ++F +KC ++G D AKA + +GI+FI
Sbjct: 65 FTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGG-SDKAKAKIACLAGIVFI 123
Query: 127 VSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTL 186
+SGLC++ G S++AN + T F+ V+ +Y GAALF+GW L +
Sbjct: 124 LSGLCSMTGCSLYANKITTEFFDPL------------FVEQKYELGAALFIGWAGASLCI 171
Query: 187 IGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKIYDGGAR 246
IGGV+ C + N K Y +G A++ S TK Y GG
Sbjct: 172 IGGVIFCFSI------SDNNKTPRYTYNG-----------ATSVMSSRTK----YHGG-- 208
Query: 247 TEDEVQSYPSK 257
ED + PSK
Sbjct: 209 -EDFKTTNPSK 218
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 135 bits (339), Expect = 5e-32
Identities = 81/257 (31%), Positives = 129/257 (50%), Gaps = 37/257 (14%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGF 60
M++T +++AF++SI G + D W + +T+ + LW++CV S+G
Sbjct: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGV 60
Query: 61 TECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLT 120
+ C+ + ++L L +QA R LMI + LG G + ++F +KC ++G D AKA +
Sbjct: 61 SNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGG-SDKAKAKIACL 119
Query: 121 SGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWV 180
+GI+FI+SGLC++ G S++AN + T F+ V+ +Y GAALF+GW
Sbjct: 120 AGIVFILSGLCSMTGCSLYANKITTEFFDPL------------FVEQKYELGAALFIGWA 167
Query: 181 AGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKI 240
L +IGGV+ C + N K Y +G A++ S TK
Sbjct: 168 GASLCIIGGVIFCFSI------SDNNKTPRYTYNG-----------ATSVMSSRTK---- 206
Query: 241 YDGGARTEDEVQSYPSK 257
Y GG ED + PSK
Sbjct: 207 YHGG---EDFKTTNPSK 220
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 129 bits (323), Expect = 3e-30
Identities = 80/232 (34%), Positives = 123/232 (53%), Gaps = 20/232 (8%)
Query: 7 QVVAFLLSILGLAGCIAATGMDMWSTQDLY-DNPVTSVFQYEGLWRSCVRQSSGFTECRP 65
++ L++LG G I + MW N +TS +EGLW +CV QS+G +C+
Sbjct: 6 EITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKV 65
Query: 66 YFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMF 125
Y ++L LP LQA RAL++V I+L A GLLV++ +C +D+AKA +T+ +G++F
Sbjct: 66 YDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNC-VQDDTAKAKITIVAGVLF 124
Query: 126 IVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLT 185
+++ L + VS AN ++ +F+ +V Q R GA L+VGW A L
Sbjct: 125 LLAALLTLVPVSWSANTIIRDFY----------NPVVPEAQKR-EMGAGLYVGWAAAALQ 173
Query: 186 LIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKN 237
L+GG ++C +C P E Y A S A + G AS G G + K+
Sbjct: 174 LLGGALLCCSC---PPREKKYTATKVVYS----APRSTGPGASLGTGYDRKD 218
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 125 bits (313), Expect = 5e-29
Identities = 77/221 (34%), Positives = 123/221 (55%), Gaps = 15/221 (6%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWS-TQDLYDNPVTSVFQYEGLWRSCVRQSSG 59
M++ QV+ L++LG + + MW T + N VTS +EGLW +CV QS+G
Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
+C+ Y ++L LP LQA RAL+I+ I++ A+G+L+S+ KC ++SAKA +
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNC-LEDESAKAKTMI 119
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
+G++F+++GL I VS A+ ++ +F+ +V + Q R GA+L+VGW
Sbjct: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFY----------NPLVASGQKR-EMGASLYVGW 168
Query: 180 VAGGLTLIGGVMMCIAC--RGLAPEETNYKAVSYHASGHSV 218
A GL L+GG ++C C R P Y A A+ + V
Sbjct: 169 AASGLLLLGGGLLCCNCPPRTDKPYSAKYSAARSAAASNYV 209
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 123 bits (309), Expect = 1e-28
Identities = 70/226 (30%), Positives = 119/226 (52%), Gaps = 13/226 (5%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNP-VTSVFQYEGLWRSCVRQSSG 59
M++ Q++ +L++LG + + + MW N V + +EGLW SCV QS+G
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
+C+ Y ++L LP LQA RAL ++ +++ GLLV + KC +DS KA + L
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDS-KARLVL 119
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
TSGI+F++SG+ + V A+ ++ +F+ +V Q R GA+L++GW
Sbjct: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFY----------NPLVAEAQKR-ELGASLYLGW 168
Query: 180 VAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGF 225
A GL L+GG ++C C + ++ Y S +++ P +
Sbjct: 169 AASGLLLLGGGLLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEY 214
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 122 bits (305), Expect = 4e-28
Identities = 68/202 (33%), Positives = 113/202 (55%), Gaps = 13/202 (6%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWS-TQDLYDNPVTSVFQYEGLWRSCVRQSSG 59
M++T Q++ FLLS LG+ G + T + W T + N +T+V +GLW CV S+G
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
+C+ Y ++L LP LQA RALM++ +L I ++ +KC R + AK +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
G +FI++GL + VS N +V NF+ + +GM ++ G AL++G+
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFY--NPLLPSGM---------KFEIGQALYLGF 168
Query: 180 VAGGLTLIGGVMMCIACRGLAP 201
++ L+LIGG ++C++C+ AP
Sbjct: 169 ISSSLSLIGGTLLCLSCQDEAP 190
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 122 bits (305), Expect = 4e-28
Identities = 68/202 (33%), Positives = 113/202 (55%), Gaps = 13/202 (6%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWS-TQDLYDNPVTSVFQYEGLWRSCVRQSSG 59
M++T Q++ FLLS LG+ G + T + W T + N +T+V +GLW CV S+G
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
+C+ Y ++L LP LQA RALM++ +L I ++ +KC R + AK +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
G +FI++GL + VS N +V NF+ + +GM ++ G AL++G+
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFY--NPLLPSGM---------KFEIGQALYLGF 168
Query: 180 VAGGLTLIGGVMMCIACRGLAP 201
++ L+LIGG ++C++C+ AP
Sbjct: 169 ISSSLSLIGGTLLCLSCQDEAP 190
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 122 bits (305), Expect = 4e-28
Identities = 68/202 (33%), Positives = 113/202 (55%), Gaps = 13/202 (6%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWS-TQDLYDNPVTSVFQYEGLWRSCVRQSSG 59
M++T Q++ FLLS LG+ G + T + W T + N +T+V +GLW CV S+G
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
+C+ Y ++L LP LQA RALM++ +L I ++ +KC R + AK +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
G +FI++GL + VS N +V NF+ + +GM ++ G AL++G+
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFY--NPLLPSGM---------KFEIGQALYLGF 168
Query: 180 VAGGLTLIGGVMMCIACRGLAP 201
++ L+LIGG ++C++C+ AP
Sbjct: 169 ISSSLSLIGGTLLCLSCQDEAP 190
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 122 bits (305), Expect = 4e-28
Identities = 68/202 (33%), Positives = 113/202 (55%), Gaps = 13/202 (6%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWS-TQDLYDNPVTSVFQYEGLWRSCVRQSSG 59
M++T Q++ FLLS LG+ G + T + W T + N +T+V +GLW CV S+G
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
+C+ Y ++L LP LQA RALM++ +L I ++ +KC R + AK +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
G +FI++GL + VS N +V NF+ + +GM ++ G AL++G+
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFY--NPLLPSGM---------KFEIGQALYLGF 168
Query: 180 VAGGLTLIGGVMMCIACRGLAP 201
++ L+LIGG ++C++C+ AP
Sbjct: 169 ISSSLSLIGGTLLCLSCQDEAP 190
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 122 bits (305), Expect = 4e-28
Identities = 68/202 (33%), Positives = 113/202 (55%), Gaps = 13/202 (6%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWS-TQDLYDNPVTSVFQYEGLWRSCVRQSSG 59
M++T Q++ FLLS LG+ G + T + W T + N +T+V +GLW CV S+G
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
+C+ Y ++L LP LQA RALM++ +L I ++ +KC R + AK +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAI 119
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
G +FI++GL + VS N +V NF+ + +GM ++ G AL++G+
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFY--NPLLPSGM---------KFEIGQALYLGF 168
Query: 180 VAGGLTLIGGVMMCIACRGLAP 201
++ L+LIGG ++C++C+ AP
Sbjct: 169 ISSSLSLIGGTLLCLSCQDEAP 190
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 118 bits (295), Expect = 6e-27
Identities = 62/194 (31%), Positives = 105/194 (54%), Gaps = 13/194 (6%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYD-NPVTSVFQYEGLWRSCVRQSSG 59
M + +++ +L ++G G I A G+ MW D N VT+ ++GLW SCV QS+G
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
+C+ Y ++L L +QA RAL + ++L + L V++ +C + AKA + L
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVA-PGPAKARVAL 204
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
T G++++ GL A+ + FAN++V F+ + V +Y GAAL++GW
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSV-----------PVSQKYELGAALYIGW 253
Query: 180 VAGGLTLIGGVMMC 193
A L ++GG ++C
Sbjct: 254 AATALLMVGGCLLC 267
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 118 bits (295), Expect = 6e-27
Identities = 62/194 (31%), Positives = 105/194 (54%), Gaps = 13/194 (6%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYD-NPVTSVFQYEGLWRSCVRQSSG 59
M + +++ +L ++G G I A G+ MW D N VT+ ++GLW SCV QS+G
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
+C+ Y ++L L +QA RAL + ++L + L V++ +C + AKA + L
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVA-PGPAKARVAL 204
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
T G++++ GL A+ + FAN++V F+ + V +Y GAAL++GW
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSV-----------PVSQKYELGAALYIGW 253
Query: 180 VAGGLTLIGGVMMC 193
A L ++GG ++C
Sbjct: 254 AATALLMVGGCLLC 267
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 115 bits (287), Expect = 5e-26
Identities = 61/190 (32%), Positives = 101/190 (53%), Gaps = 12/190 (6%)
Query: 7 QVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTECRPY 66
+ F ++ +GL W ++ N +T+ +E LW SC S G C +
Sbjct: 6 ETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWEF 65
Query: 67 FTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFI 126
++L L +QA RALMI I+LG +GLL+ I L+C IG +E S KA + T+G + I
Sbjct: 66 PSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHI 125
Query: 127 VSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTL 186
++G+C + +S +A + +F+ +Y G T+Y G AL++GW A +++
Sbjct: 126 LAGICGMVAISWYAFNITRDFF---DPLYPG---------TKYELGPALYLGWSASLISI 173
Query: 187 IGGVMMCIAC 196
+GG+ +C AC
Sbjct: 174 LGGLCLCSAC 183
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 113 bits (283), Expect = 1e-25
Identities = 60/195 (30%), Positives = 103/195 (52%), Gaps = 14/195 (7%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQ--YEGLWRSCVRQSS 58
M+T ++ L +G+ G +A T M W +N + VF+ +EGLW +CVRQ++
Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIV-VFENFWEGLWMNCVRQAN 59
Query: 59 GFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMT 118
+C+ Y ++L L LQA R LM V+ + +++I +KC R + KA++
Sbjct: 60 IRMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHIL 119
Query: 119 LTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVG 178
LT+GI+FI++G+ + VS AN ++ +F+ S N V + G AL++G
Sbjct: 120 LTAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVN-----------VAQKRELGEALYLG 168
Query: 179 WVAGGLTLIGGVMMC 193
W + ++GG + C
Sbjct: 169 WTTALVLIVGGALFC 183
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 112 bits (280), Expect = 3e-25
Identities = 74/208 (35%), Positives = 103/208 (49%), Gaps = 13/208 (6%)
Query: 4 TTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTEC 63
T Q V LLS+LG I T + W +L N + + GLW++CV Q +C
Sbjct: 7 TAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
Query: 64 RPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGI 123
+ + + L LPA L+ R LM + LG +GLLVS F L C+RIG + K + + GI
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 124 MFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGG 183
+ SG+ A+ VS A+ V FW V R+ FG ALF+GW AG
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDEN----------VPDFVPRWEFGEALFLGWFAGL 174
Query: 184 LTLIGGVMM-CIACRGLAPEETNYKAVS 210
L+GG ++ C AC AP + AV+
Sbjct: 175 SLLLGGCLLNCAACSSHAPLALGHYAVA 202
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 112 bits (279), Expect = 4e-25
Identities = 58/197 (29%), Positives = 108/197 (54%), Gaps = 13/197 (6%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNP-VTSVFQYEGLWRSCVRQSSG 59
M++T +++ L++LG G + + + +W N V + +EGLW SCV QS+G
Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
+C+ Y ++L LP LQA RAL ++ ++L +GLLV+I +C ++ AKA + L
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVE-DEGAKARIVL 119
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
T+G++ +++G+ + V A+ ++ +F+ + + GA+L++GW
Sbjct: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFY-----------NPLVAEALKRELGASLYLGW 168
Query: 180 VAGGLTLIGGVMMCIAC 196
A L ++GG ++C C
Sbjct: 169 AAAALLMLGGGLLCCTC 185
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 111 bits (278), Expect = 6e-25
Identities = 74/208 (35%), Positives = 102/208 (49%), Gaps = 13/208 (6%)
Query: 4 TTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTEC 63
T Q V LLS LG I T + W +L N + + GLW++CV Q +C
Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
Query: 64 RPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGI 123
+ + + L LPA L+ R LM + LG +GLLVS F L C+RIG + K + + GI
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 124 MFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGG 183
+ SG+ A+ VS A+ V FW V R+ FG ALF+GW AG
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDEN----------VPDFVPRWEFGEALFLGWFAGL 174
Query: 184 LTLIGGVMM-CIACRGLAPEETNYKAVS 210
L+GG ++ C AC AP + AV+
Sbjct: 175 SLLLGGCLLNCAACSSHAPLALGHYAVA 202
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 111 bits (278), Expect = 6e-25
Identities = 74/208 (35%), Positives = 102/208 (49%), Gaps = 13/208 (6%)
Query: 4 TTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTEC 63
T Q V LLS LG I T + W +L N + + GLW++CV Q +C
Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
Query: 64 RPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGI 123
+ + + L LPA L+ R LM + LG +GLLVS F L C+RIG + K + + GI
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 124 MFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGG 183
+ SG+ A+ VS A+ V FW V R+ FG ALF+GW AG
Sbjct: 125 LSWASGITALVPVSWVAHKTVQEFWDEN----------VPDFVPRWEFGEALFLGWFAGL 174
Query: 184 LTLIGGVMM-CIACRGLAPEETNYKAVS 210
L+GG ++ C AC AP + AV+
Sbjct: 175 SLLLGGCLLNCAACSSHAPLALGHYAVA 202
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 111 bits (278), Expect = 6e-25
Identities = 60/192 (31%), Positives = 103/192 (53%), Gaps = 14/192 (7%)
Query: 7 QVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQ--YEGLWRSCVRQSSGFTECR 64
Q+ +L LG+ G +A T + W + + VF+ +EGLW +C+RQ+ +C+
Sbjct: 7 QIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNII-VFERLWEGLWMNCIRQARVRLQCK 65
Query: 65 PYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIM 124
Y ++L LP L+ RALM V + L I LL+ I +K ++ + AKA + TSG++
Sbjct: 66 FYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVL 125
Query: 125 FIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGL 184
FI++G+ + VS AN+++ +F+ + + + GAALF+GW + +
Sbjct: 126 FILTGIFVLIPVSWTANIIIRDFYNPAIH-----------IGQKRELGAALFLGWASAAV 174
Query: 185 TLIGGVMMCIAC 196
IGG ++C C
Sbjct: 175 LFIGGGLLCGFC 186
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 110 bits (275), Expect = 1e-24
Identities = 75/251 (29%), Positives = 114/251 (45%), Gaps = 56/251 (22%)
Query: 7 QVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTECRPY 66
Q+ A + + G +AAT + W + +T+ + Y+GLW +C
Sbjct: 5 QIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCA------------ 52
Query: 67 FTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFI 126
+QA R LMI + LG G + ++F +KC ++G D AKA + +GI+FI
Sbjct: 53 -------GYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGG-SDKAKAKIACLAGIVFI 104
Query: 127 VSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTL 186
+SGLC++ G S++AN + T F+ V+ +Y GAALF+GW L +
Sbjct: 105 LSGLCSMTGCSLYANKITTEFFDPL------------FVEQKYELGAALFIGWAGASLCI 152
Query: 187 IGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKIYDGGAR 246
IGGV+ C + N K Y +G A++ S TK Y GG
Sbjct: 153 IGGVIFCFSI------SDNNKTPRYTYNG-----------ATSVMSSRTK----YHGG-- 189
Query: 247 TEDEVQSYPSK 257
ED + PSK
Sbjct: 190 -EDFKTTNPSK 199
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 107 bits (267), Expect = 1e-23
Identities = 71/214 (33%), Positives = 102/214 (47%), Gaps = 13/214 (6%)
Query: 4 TTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTEC 63
T Q+ LS+LG + W +L N + + GLW++CV Q +C
Sbjct: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
Query: 64 RPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGI 123
+ + + L LPA L+ R LM + LG +GLLVS F L C+RIG + K + + GI
Sbjct: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
Query: 124 MFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGG 183
+ SG+ A+ VS A+ V FW V R+ FG ALF+GW AG
Sbjct: 125 LSWASGVTALVPVSWVAHKTVQEFWDEN----------VPDFVPRWEFGEALFLGWFAGL 174
Query: 184 LTLIGGVMM-CIACRGLAPEETNYKAVSYHASGH 216
L+GG ++ C AC AP + + AV+ H
Sbjct: 175 SLLLGGCLLHCAACSSHAPLASGHYAVAQTQDHH 208
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 105 bits (263), Expect = 3e-23
Identities = 56/203 (27%), Positives = 104/203 (51%), Gaps = 13/203 (6%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQ-DLYDNPVTSVFQYEGLWRSCVRQSSG 59
M++ Q++AF+L++ G++G + AT + W D+ N +T++ Q GLW C S+G
Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
C +IL LP +QA RA M++ VL A+G+ S +KC R+G + K++ +
Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGG-DRETKSHASF 119
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
G+ F+ +G+ ++ + ++ NF T ++ G A+++G+
Sbjct: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTV-----------PESNKHEPGGAIYIGF 168
Query: 180 VAGGLTLIGGVMMCIACRGLAPE 202
++ L I G++ C +C PE
Sbjct: 169 ISAMLLFISGMIFCTSCIKRNPE 191
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 102 bits (255), Expect = 3e-22
Identities = 58/224 (25%), Positives = 109/224 (48%), Gaps = 13/224 (5%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYD-NPVTSVFQYEGLWRSCVRQSSG 59
M++ Q+V ++L +LGL G + A + W T + VT+V +GLW C S+G
Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
Query: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
T+C Y T+LGLPA +QA +A+M+ + ++ ++S+ ++C + E AK + +
Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRC-TVFCQESRAKDRVAV 119
Query: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
G+ FI+ GL V+ + ++ +F+ + ++ G AL++G
Sbjct: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFY-----------SPLVPDSMKFEIGEALYLGI 168
Query: 180 VAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPG 223
++ +LI G+++C +C Y A + +PG
Sbjct: 169 ISSLFSLIAGIILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPG 212
>gi|10938016 claudin 11 [Homo sapiens]
Length = 207
Score = 95.1 bits (235), Expect = 5e-20
Identities = 70/221 (31%), Positives = 96/221 (43%), Gaps = 28/221 (12%)
Query: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQY---EGLWRSCVRQS 57
M T QVV F+ S +G G I T + W Y P +GLW CV +
Sbjct: 1 MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCV-MA 59
Query: 58 SGFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANM 117
+G C+P IL LP +QA RALMI VLG +L+ + L CIR+G AK
Sbjct: 60 TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
Query: 118 TLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFV 177
+G++ I+ LCA LV W T +FG +L+
Sbjct: 120 AQLAGVLLILLALCA----------LVATIWFPVC---------AHRETTIVSFGYSLYA 160
Query: 178 GWVAGGLTLIGG-VMMCIACRGLAPEETNYKAVSYHASGHS 217
GW+ L L+GG V++C A A E + Y+ +G S
Sbjct: 161 GWIGAVLCLVGGCVILCCAGDAQAFGENRF----YYTAGSS 197
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.135 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,034,956
Number of Sequences: 37866
Number of extensions: 355799
Number of successful extensions: 1249
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 1130
Number of HSP's gapped (non-prelim): 71
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.