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Search of human proteins with 7705917
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo
sapiens]
(399 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo sa... 841 0.0
gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo ... 769 0.0
gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo ... 749 0.0
gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens] 456 e-128
gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens] 452 e-127
gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens] 451 e-127
gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens] 451 e-127
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] 433 e-121
gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens] 397 e-110
gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens] 389 e-108
gi|42518080 transcription factor 7 (T-cell specific, HMG-box) is... 290 2e-78
gi|42518078 transcription factor 7 (T-cell specific, HMG-box) is... 234 1e-61
gi|47419938 transcription factor 7 (T-cell specific, HMG-box) is... 234 1e-61
gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5... 233 2e-61
gi|42714657 transcription factor 7 (T-cell specific, HMG-box) is... 233 2e-61
gi|42518074 transcription factor 7 (T-cell specific, HMG-box) is... 233 3e-61
gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6... 231 7e-61
gi|112421108 capicua homolog [Homo sapiens] 69 1e-11
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 64 3e-10
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 64 3e-10
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 64 3e-10
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 64 3e-10
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 61 2e-09
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 61 2e-09
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 59 1e-08
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 59 1e-08
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 59 1e-08
gi|41406089 SRY-box 13 [Homo sapiens] 58 2e-08
gi|4507161 SRY-box 11 [Homo sapiens] 57 4e-08
gi|13899269 SRY-box 7 [Homo sapiens] 55 9e-08
>gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo
sapiens]
Length = 399
Score = 841 bits (2173), Expect = 0.0
Identities = 399/399 (100%), Positives = 399/399 (100%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
Sbjct: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
Query: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
Sbjct: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
Query: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS 240
KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS
Sbjct: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS 240
Query: 241 RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK 300
RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
Sbjct: 241 RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK 300
Query: 301 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM 360
KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
Sbjct: 301 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM 360
Query: 361 QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI 399
QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI
Sbjct: 361 QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI 399
>gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo
sapiens]
Length = 371
Score = 769 bits (1986), Expect = 0.0
Identities = 371/399 (92%), Positives = 371/399 (92%), Gaps = 28/399 (7%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
Sbjct: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
Query: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
Sbjct: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
Query: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS 240
KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW
Sbjct: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW--------------------------- 213
Query: 241 RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK 300
FSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
Sbjct: 214 -FSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK 272
Query: 301 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM 360
KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
Sbjct: 273 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM 332
Query: 361 QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI 399
QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI
Sbjct: 333 QLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAAYI 371
>gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo
sapiens]
Length = 386
Score = 749 bits (1934), Expect = 0.0
Identities = 361/389 (92%), Positives = 361/389 (92%), Gaps = 28/389 (7%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
Sbjct: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
Query: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
Sbjct: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
Query: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS 240
KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW
Sbjct: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW--------------------------- 213
Query: 241 RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK 300
FSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
Sbjct: 214 -FSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK 272
Query: 301 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM 360
KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
Sbjct: 273 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM 332
Query: 361 QLYPGWSARDNYGKKKKRKREKLQESASG 389
QLYPGWSARDNYGKKKKRKREKLQESASG
Sbjct: 333 QLYPGWSARDNYGKKKKRKREKLQESASG 361
>gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens]
Length = 455
Score = 456 bits (1174), Expect = e-128
Identities = 249/418 (59%), Positives = 290/418 (69%), Gaps = 48/418 (11%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSNGSLSP---------------------------------PIPRTSNKVPVV 145
++ + PY+ NGSLSP P SNKVPVV
Sbjct: 110 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV 168
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Q H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K G+ R P PDI +YPLSPG VG
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 206 QITPPLGWQGQPVYPIT-GGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIV 264
QI PLGWQGQPVYPIT GGFR PYP++L+V+ SMSRF HM+P HTTGIPHPAIV
Sbjct: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
Query: 265 TPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLK 324
TP VKQE +D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAECTLK
Sbjct: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
Query: 325 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREK 382
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR+K
Sbjct: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDK 406
>gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]
Length = 442
Score = 452 bits (1164), Expect = e-127
Identities = 252/438 (57%), Positives = 294/438 (67%), Gaps = 52/438 (11%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSNGSLSP---------------------------------PIPRTSNKVPVV 145
++ + PY+ NGSLSP P SNKVPVV
Sbjct: 110 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV 168
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Q H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K G+ R P PDI +YPLSPG VG
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 206 QITPPLGW----QGQPVYPIT-GGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPH 260
QI PLGW QGQPVYPIT GGFR PYP++L+V+ SMSRF HM+P HTTGIPH
Sbjct: 229 QIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPH 288
Query: 261 PAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAE 320
PAIVTP VKQE +D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAE
Sbjct: 289 PAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAE 348
Query: 321 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 380
CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR
Sbjct: 349 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 408
Query: 381 EKLQESASGTGPRMTAAY 398
+K +G A Y
Sbjct: 409 DKQPGETNGEKKSAFATY 426
>gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]
Length = 596
Score = 451 bits (1159), Expect = e-127
Identities = 249/422 (59%), Positives = 290/422 (68%), Gaps = 52/422 (12%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSNGSLSP---------------------------------PIPRTSNKVPVV 145
++ + PY+ NGSLSP P SNKVPVV
Sbjct: 110 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV 168
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Q H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K G+ R P PDI +YPLSPG VG
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 206 QITPPLGW----QGQPVYPIT-GGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPH 260
QI PLGW QGQPVYPIT GGFR PYP++L+V+ SMSRF HM+P HTTGIPH
Sbjct: 229 QIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPH 288
Query: 261 PAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAE 320
PAIVTP VKQE +D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAE
Sbjct: 289 PAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAE 348
Query: 321 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 380
CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR
Sbjct: 349 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 408
Query: 381 EK 382
+K
Sbjct: 409 DK 410
>gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]
Length = 579
Score = 451 bits (1159), Expect = e-127
Identities = 249/422 (59%), Positives = 290/422 (68%), Gaps = 52/422 (12%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSNGSLSP---------------------------------PIPRTSNKVPVV 145
++ + PY+ NGSLSP P SNKVPVV
Sbjct: 110 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV 168
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Q H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K G+ R P PDI +YPLSPG VG
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 206 QITPPLGW----QGQPVYPIT-GGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPH 260
QI PLGW QGQPVYPIT GGFR PYP++L+V+ SMSRF HM+P HTTGIPH
Sbjct: 229 QIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPH 288
Query: 261 PAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAE 320
PAIVTP VKQE +D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAE
Sbjct: 289 PAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAE 348
Query: 321 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 380
CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR
Sbjct: 349 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 408
Query: 381 EK 382
+K
Sbjct: 409 DK 410
>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
Length = 602
Score = 433 bits (1114), Expect = e-121
Identities = 249/445 (55%), Positives = 290/445 (65%), Gaps = 75/445 (16%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSN---------------------------------------------GSL-- 131
++ + PY+ N GSL
Sbjct: 110 DLTS-PYLPNGSLSPTARTLHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQS 168
Query: 132 --------SP-PIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQ 182
SP P SNKVPVVQ H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K
Sbjct: 169 RQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKT 228
Query: 183 GMSRHPPAPDIPTFYPLSPGGVGQITPPLGW----QGQPVYPIT-GGFRQPYPSSLSVDT 237
G+ R P PDI +YPLSPG VGQI PLGW QGQPVYPIT GGFR PYP++L+V+
Sbjct: 229 GIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNA 288
Query: 238 SMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRP 297
SMSRF HM+P HTTGIPHPAIVTP VKQE +D +H + +KE+E K+P
Sbjct: 289 SMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKP 348
Query: 298 HIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 357
HIKKPLNAFMLYMKEMRA VVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ
Sbjct: 349 HIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 408
Query: 358 LHMQLYPGWSARDNYGKKKKRKREK 382
LHMQLYPGWSARDNYGKKKKRKR+K
Sbjct: 409 LHMQLYPGWSARDNYGKKKKRKRDK 433
>gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]
Length = 588
Score = 397 bits (1019), Expect = e-110
Identities = 230/437 (52%), Positives = 285/437 (65%), Gaps = 63/437 (14%)
Query: 1 MPQLSGGGGGGGGDP---------------ELCATDEMIPFKDEGDPQKEKIFAEISHPE 45
MPQL GGGGGGGG +L A DE+IPF+DEG ++E S
Sbjct: 1 MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSAS--- 57
Query: 46 EEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKG 105
+ DL ++KSSLVNESE +S+ E R+ Q ++ + K R++ + + P + KG
Sbjct: 58 AQRDLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKG 116
Query: 106 PSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRT--------------------------- 138
P Y Y ++M+P++++ PY+SNG LSP RT
Sbjct: 117 PPYPGYP-FLMIPDLSS-PYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAH 174
Query: 139 -SNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFY 197
SNKVPVVQ H +HPLTPLITYS++HFSPGS P+H+ +++ K G+ R P ++ +Y
Sbjct: 175 LSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYY 234
Query: 198 PLSPGGVGQITPPLGW----QGQPVYPIT-GGFRQPYPSSLSVDTSMS-----RFSHHMI 247
PLSPG VGQI PLGW QGQP+Y + GGFR PYP+ L+++ SMS RFS HM+
Sbjct: 235 PLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPA-LAMNASMSSLVSSRFSPHMV 293
Query: 248 -PGPPGPHTTGIPHPAIVTPQVKQEH-PHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNA 305
P PG T+GIPHPAIV+P VKQE P + S + VK +KE+E K+PH+KKPLNA
Sbjct: 294 APAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEE-KKPHVKKPLNA 352
Query: 306 FMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPG 365
FMLYMKEMRA VVAECTLKESAAINQILGR+WH LSREEQAKYYELARKERQLH QLYP
Sbjct: 353 FMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPT 412
Query: 366 WSARDNYGKKKKRKREK 382
WSARDNYGKKKKRKREK
Sbjct: 413 WSARDNYGKKKKRKREK 429
>gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens]
Length = 489
Score = 389 bits (999), Expect = e-108
Identities = 242/487 (49%), Positives = 286/487 (58%), Gaps = 103/487 (21%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDD-GKHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSNGSLSPPIPRT--SNKVPVV-------------------QPSHAVHPLTPL 157
++ + PY+ NGSLS P RT K P++ P+H V PL P
Sbjct: 110 DLTS-PYLPNGSLS-PTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSPL-PC 166
Query: 158 IT--YSDEHFSPGS------------------------------------HPSHI----- 174
T + +HF P S HP H+
Sbjct: 167 CTQGHDCQHFYPPSDFTVSTQVFRDMKRSHSLQKVGEPWCIESNKVPVVQHPHHVHPLTP 226
Query: 175 ------------------PSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW--- 213
P+DV+ K G+ R P PDI +YPLSPG VGQI PLGW
Sbjct: 227 LITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVP 286
Query: 214 -QGQPVYPI-TGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQE 271
QGQPVYPI TGGFR PYP++L+V+ SMSRF HM+P HTTGIPHPAIVTP VKQE
Sbjct: 287 QQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQE 346
Query: 272 HPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQ 331
+D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAECTLKESAAINQ
Sbjct: 347 SSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQ 406
Query: 332 ILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGTG 391
ILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR+K +G
Sbjct: 407 ILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNGEK 466
Query: 392 PRMTAAY 398
A Y
Sbjct: 467 KSAFATY 473
>gi|42518080 transcription factor 7 (T-cell specific, HMG-box)
isoform 1 [Homo sapiens]
Length = 384
Score = 290 bits (741), Expect = 2e-78
Identities = 185/406 (45%), Positives = 230/406 (56%), Gaps = 64/406 (15%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL GGGG GG +L A DE++ F+DEG+ Q +K + PE DLA++KSSLVNE
Sbjct: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPER--DLAELKSSLVNE 58
Query: 61 SEIIPASNG--------------HEVARQAQTSQEPYHDKAREHPDDG-KHPD--GGLYN 103
SE G E + +Q + DK E +DG K P+ G+Y
Sbjct: 59 SEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYK 118
Query: 104 KGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDE 163
+ + YS + ++ M+ P G P P P+ + + H + L Y E
Sbjct: 119 E----TVYSAFNLL--MHYPPPSGAGQHPQPQP------PLHKANQPPHGVPQLSLY--E 164
Query: 164 HFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITG 223
HF+ HP+ P+D++ KQ + R PD+ FY L+ G +GQ+ + W P +
Sbjct: 165 HFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGS 222
Query: 224 GFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVK 283
G +PG H IPHPAIV P KQE D +L K
Sbjct: 223 G----------------------VPG----HPAAIPHPAIVPPSGKQELQPFDRNL---K 253
Query: 284 PQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSRE 343
Q E + E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKESAAINQILGRRWHALSRE
Sbjct: 254 TQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSRE 313
Query: 344 EQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASG 389
EQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R REK QES +G
Sbjct: 314 EQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTG 359
>gi|42518078 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 234 bits (596), Expect = 1e-61
Identities = 133/244 (54%), Positives = 154/244 (63%), Gaps = 36/244 (14%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVT 265
Q+ + W P + G +PG H IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSG----------------------VPG----HPAAIPHPAIVP 123
Query: 266 PQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKE 325
P KQE D +L K Q E + E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKE
Sbjct: 124 PSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 326 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQE 385
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R REK QE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 386 SASG 389
S +G
Sbjct: 241 STTG 244
>gi|47419938 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 234 bits (596), Expect = 1e-61
Identities = 133/244 (54%), Positives = 154/244 (63%), Gaps = 36/244 (14%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVT 265
Q+ + W P + G +PG H IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSG----------------------VPG----HPAAIPHPAIVP 123
Query: 266 PQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKE 325
P KQE D +L K Q E + E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKE
Sbjct: 124 PSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 326 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQE 385
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R REK QE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 386 SASG 389
S +G
Sbjct: 241 STTG 244
>gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5
[Homo sapiens]
Length = 366
Score = 233 bits (594), Expect = 2e-61
Identities = 133/246 (54%), Positives = 154/246 (62%), Gaps = 36/246 (14%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVT 265
Q+ + W P + G +PG H IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSG----------------------VPG----HPAAIPHPAIVP 123
Query: 266 PQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKE 325
P KQE D +L K Q E + E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKE
Sbjct: 124 PSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 326 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQE 385
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R REK QE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 386 SASGTG 391
S + G
Sbjct: 241 STTDPG 246
>gi|42714657 transcription factor 7 (T-cell specific, HMG-box)
isoform 4 [Homo sapiens]
Length = 268
Score = 233 bits (594), Expect = 2e-61
Identities = 133/246 (54%), Positives = 154/246 (62%), Gaps = 36/246 (14%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVT 265
Q+ + W P + G +PG H IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSG----------------------VPG----HPAAIPHPAIVP 123
Query: 266 PQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKE 325
P KQE D +L K Q E + E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKE
Sbjct: 124 PSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 326 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQE 385
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R REK QE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 386 SASGTG 391
S + G
Sbjct: 241 STTDPG 246
>gi|42518074 transcription factor 7 (T-cell specific, HMG-box)
isoform 3 [Homo sapiens]
Length = 269
Score = 233 bits (593), Expect = 3e-61
Identities = 133/245 (54%), Positives = 154/245 (62%), Gaps = 36/245 (14%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVT 265
Q+ + W P + G +PG H IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSG----------------------VPG----HPAAIPHPAIVP 123
Query: 266 PQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKE 325
P KQE D +L K Q E + E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKE
Sbjct: 124 PSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 326 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQE 385
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R REK QE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 386 SASGT 390
S + T
Sbjct: 241 STTET 245
>gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6
[Homo sapiens]
Length = 250
Score = 231 bits (590), Expect = 7e-61
Identities = 132/243 (54%), Positives = 153/243 (62%), Gaps = 36/243 (14%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGIPHPAIVT 265
Q+ + W P + G +PG H IPHPAIV
Sbjct: 90 QLPHTVSWFTHPSLMLGSG----------------------VPG----HPAAIPHPAIVP 123
Query: 266 PQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKE 325
P KQE D +L K Q E + E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKE
Sbjct: 124 PSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKE 180
Query: 326 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQE 385
SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK+R REK QE
Sbjct: 181 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQE 240
Query: 386 SAS 388
S +
Sbjct: 241 STT 243
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 68.6 bits (166), Expect = 1e-11
Identities = 67/269 (24%), Positives = 113/269 (42%), Gaps = 40/269 (14%)
Query: 142 VPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSP 201
VP + PS + P E P SHP V S Q PA + P
Sbjct: 41 VPFLAPSQPDPSVQP-----SEAQQPASHP------VASNQSKE---PAESAAVAHERPP 86
Query: 202 GGVGQITP--PLGWQGQPVYPITGGFRQPYPSSLSVDTSMSR--FSHHMIPGPPGP---- 253
GG G P P G P + G P+P + V++ + GPPG
Sbjct: 87 GGTGSADPERPPG----ATCPESPGPGPPHPLGV-VESGKGPPPTTEEEASGPPGEPRLD 141
Query: 254 HTTGIPHP----AIVTPQVKQEHP---HTDSDLMHVKPQHEQRKEQEPKRP------HIK 300
T H +I++P+++ P L + + + E++ + P HI+
Sbjct: 142 SETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIR 201
Query: 301 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM 360
+P+NAFM++ K RA V +++ +++ILG W+AL +E+ KY++LA + ++ H
Sbjct: 202 RPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHF 261
Query: 361 QLYPGWSARDNYGKKKKRKREKLQESASG 389
+ +P W + KK + + +G
Sbjct: 262 KAHPDWKWCNKDRKKSSSEAKPTSLGLAG 290
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 63.5 bits (153), Expect = 3e-10
Identities = 30/84 (35%), Positives = 51/84 (60%), Gaps = 6/84 (7%)
Query: 297 PHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKER 356
PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 632 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLS 691
Query: 357 QLHMQLYPGWSARDNYGKKKKRKR 380
++H++ YP NY K + KR
Sbjct: 692 KIHLEKYP------NYKYKPRPKR 709
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 63.5 bits (153), Expect = 3e-10
Identities = 30/84 (35%), Positives = 51/84 (60%), Gaps = 6/84 (7%)
Query: 297 PHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKER 356
PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 592 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLS 651
Query: 357 QLHMQLYPGWSARDNYGKKKKRKR 380
++H++ YP NY K + KR
Sbjct: 652 KIHLEKYP------NYKYKPRPKR 669
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 63.5 bits (153), Expect = 3e-10
Identities = 30/84 (35%), Positives = 51/84 (60%), Gaps = 6/84 (7%)
Query: 297 PHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKER 356
PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 595 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLS 654
Query: 357 QLHMQLYPGWSARDNYGKKKKRKR 380
++H++ YP NY K + KR
Sbjct: 655 KIHLEKYP------NYKYKPRPKR 672
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 63.5 bits (153), Expect = 3e-10
Identities = 30/84 (35%), Positives = 51/84 (60%), Gaps = 6/84 (7%)
Query: 297 PHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKER 356
PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 599 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLS 658
Query: 357 QLHMQLYPGWSARDNYGKKKKRKR 380
++H++ YP NY K + KR
Sbjct: 659 KIHLEKYP------NYKYKPRPKR 676
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 61.2 bits (147), Expect = 2e-09
Identities = 27/80 (33%), Positives = 48/80 (60%)
Query: 298 HIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 357
H+K+P+NAFM++ + R + +A I+ LG W+ LS E++ YY+ A+K ++
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
Query: 358 LHMQLYPGWSARDNYGKKKK 377
H + +PGW + GK+K+
Sbjct: 396 KHREEFPGWVYQPRPGKRKR 415
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 61.2 bits (147), Expect = 2e-09
Identities = 27/80 (33%), Positives = 48/80 (60%)
Query: 298 HIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 357
H+K+P+NAFM++ + R + +A I+ LG W+ LS E++ YY+ A+K ++
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
Query: 358 LHMQLYPGWSARDNYGKKKK 377
H + +PGW + GK+K+
Sbjct: 396 KHREEFPGWVYQPRPGKRKR 415
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 58.5 bits (140), Expect = 1e-08
Identities = 25/81 (30%), Positives = 48/81 (59%)
Query: 286 HEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQ 345
+ + + + PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW A++ E+
Sbjct: 157 YRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEK 216
Query: 346 AKYYELARKERQLHMQLYPGW 366
YYE + + H++ YP +
Sbjct: 217 QPYYEEQARLSKQHLEKYPDY 237
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 58.5 bits (140), Expect = 1e-08
Identities = 25/81 (30%), Positives = 48/81 (59%)
Query: 286 HEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQ 345
+ + + + PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW A++ E+
Sbjct: 530 YRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEK 589
Query: 346 AKYYELARKERQLHMQLYPGW 366
YYE + + H++ YP +
Sbjct: 590 QPYYEEQARLSKQHLEKYPDY 610
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 58.5 bits (140), Expect = 1e-08
Identities = 25/81 (30%), Positives = 48/81 (59%)
Query: 286 HEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQ 345
+ + + + PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW A++ E+
Sbjct: 543 YRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEK 602
Query: 346 AKYYELARKERQLHMQLYPGW 366
YYE + + H++ YP +
Sbjct: 603 QPYYEEQARLSKQHLEKYPDY 623
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 57.8 bits (138), Expect = 2e-08
Identities = 28/88 (31%), Positives = 52/88 (59%), Gaps = 6/88 (6%)
Query: 298 HIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 357
HIK+P+NAFM++ K+ R ++ +++I++ILG RW +++ +E+ YYE + +
Sbjct: 423 HIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSR 482
Query: 358 LHMQLYPGWSARDNYGKKKKRKREKLQE 385
H++ YP +Y K + KR + E
Sbjct: 483 QHLEKYP------DYKYKPRPKRTCIVE 504
>gi|4507161 SRY-box 11 [Homo sapiens]
Length = 441
Score = 56.6 bits (135), Expect = 4e-08
Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 4/100 (4%)
Query: 298 HIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 357
HIK+P+NAFM++ K R ++ + +A I++ LG+RW L E+ + A + R
Sbjct: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
Query: 358 LHMQLYPGWSARDNYGKKKKRKREKLQESASGTGPRMTAA 397
HM YP + Y +KK K + + ++ P +AA
Sbjct: 108 KHMADYPDY----KYRPRKKPKMDPSAKPSASQSPEKSAA 143
>gi|13899269 SRY-box 7 [Homo sapiens]
Length = 388
Score = 55.5 bits (132), Expect = 9e-08
Identities = 26/80 (32%), Positives = 47/80 (58%)
Query: 299 IKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQL 358
I++P+NAFM++ K+ R + + +A ++++LG+ W AL+ ++ Y + A + R
Sbjct: 45 IRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQ 104
Query: 359 HMQLYPGWSARDNYGKKKKR 378
HMQ YP + R K+ KR
Sbjct: 105 HMQDYPNYKYRPRRKKQAKR 124
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,263,228
Number of Sequences: 37866
Number of extensions: 1198265
Number of successful extensions: 6219
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 267
Number of HSP's that attempted gapping in prelim test: 5536
Number of HSP's gapped (non-prelim): 871
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.