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Search of human proteins with 140561027
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|140561027 CASK-interacting protein CIP98 isoform 2 [Homo
sapiens]
(524 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|140561027 CASK-interacting protein CIP98 isoform 2 [Homo sapi... 1041 0.0
gi|140561024 CASK-interacting protein CIP98 isoform 1 [Homo sapi... 1041 0.0
gi|148746189 multiple PDZ domain protein [Homo sapiens] 51 2e-06
gi|222418647 mucin 7, secreted precursor [Homo sapiens] 50 5e-06
gi|222418649 mucin 7, secreted precursor [Homo sapiens] 50 5e-06
gi|222418645 mucin 7, secreted precursor [Homo sapiens] 50 5e-06
gi|9966877 golgi associated PDZ and coiled-coil motif containing... 50 5e-06
gi|62868213 golgi associated PDZ and coiled-coil motif containin... 50 5e-06
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 49 9e-06
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 49 9e-06
gi|5803177 basic beta 2 syntrophin [Homo sapiens] 49 1e-05
gi|112382257 InaD-like [Homo sapiens] 49 1e-05
gi|87196343 PDZ domain containing 2 [Homo sapiens] 49 1e-05
gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo ... 47 3e-05
gi|148833504 interleukin 16 isoform 2 [Homo sapiens] 46 7e-05
gi|27262655 interleukin 16 isoform 1 precursor [Homo sapiens] 46 7e-05
gi|223890252 glutamate receptor interacting protein 1 [Homo sapi... 46 9e-05
gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 46 9e-05
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 46 9e-05
gi|11321640 basic beta 1 syntrophin [Homo sapiens] 46 9e-05
gi|24025688 ligand of numb-protein X 2 [Homo sapiens] 45 1e-04
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 45 2e-04
gi|66346708 membrane associated guanylate kinase, WW and PDZ dom... 45 2e-04
gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo sa... 45 2e-04
gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo sa... 45 2e-04
gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens] 44 3e-04
gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens] 44 3e-04
gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens] 44 3e-04
gi|149274614 melanoma antigen family D, 4 [Homo sapiens] 44 3e-04
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i... 44 4e-04
>gi|140561027 CASK-interacting protein CIP98 isoform 2 [Homo
sapiens]
Length = 524
Score = 1041 bits (2692), Expect = 0.0
Identities = 524/524 (100%), Positives = 524/524 (100%)
Query: 1 MANSAGFLGDLTTEGINKPGFYKGPAGSQVTLSSLGNQTRVLLEEQARHLLNEQEHATMA 60
MANSAGFLGDLTTEGINKPGFYKGPAGSQVTLSSLGNQTRVLLEEQARHLLNEQEHATMA
Sbjct: 1 MANSAGFLGDLTTEGINKPGFYKGPAGSQVTLSSLGNQTRVLLEEQARHLLNEQEHATMA 60
Query: 61 YYLDEYRGGSVSVEALVMALFKLLNTHAKFSLLSEVRGTISPQDLERFDHLVLRREIESM 120
YYLDEYRGGSVSVEALVMALFKLLNTHAKFSLLSEVRGTISPQDLERFDHLVLRREIESM
Sbjct: 61 YYLDEYRGGSVSVEALVMALFKLLNTHAKFSLLSEVRGTISPQDLERFDHLVLRREIESM 120
Query: 121 KARQPPGPGAGDTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNINALPD 180
KARQPPGPGAGDTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNINALPD
Sbjct: 121 KARQPPGPGAGDTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNINALPD 180
Query: 181 VSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSA 240
VSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSA
Sbjct: 181 VSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSA 240
Query: 241 PQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRV 300
PQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRV
Sbjct: 241 PQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRV 300
Query: 301 QSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQ 360
QSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQ
Sbjct: 301 QSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQ 360
Query: 361 TRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGA 420
TRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGA
Sbjct: 361 TRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGA 420
Query: 421 NKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHV 480
NKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHV
Sbjct: 421 NKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHV 480
Query: 481 ILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFNVML 524
ILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFNVML
Sbjct: 481 ILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFNVML 524
>gi|140561024 CASK-interacting protein CIP98 isoform 1 [Homo
sapiens]
Length = 907
Score = 1041 bits (2692), Expect = 0.0
Identities = 524/524 (100%), Positives = 524/524 (100%)
Query: 1 MANSAGFLGDLTTEGINKPGFYKGPAGSQVTLSSLGNQTRVLLEEQARHLLNEQEHATMA 60
MANSAGFLGDLTTEGINKPGFYKGPAGSQVTLSSLGNQTRVLLEEQARHLLNEQEHATMA
Sbjct: 384 MANSAGFLGDLTTEGINKPGFYKGPAGSQVTLSSLGNQTRVLLEEQARHLLNEQEHATMA 443
Query: 61 YYLDEYRGGSVSVEALVMALFKLLNTHAKFSLLSEVRGTISPQDLERFDHLVLRREIESM 120
YYLDEYRGGSVSVEALVMALFKLLNTHAKFSLLSEVRGTISPQDLERFDHLVLRREIESM
Sbjct: 444 YYLDEYRGGSVSVEALVMALFKLLNTHAKFSLLSEVRGTISPQDLERFDHLVLRREIESM 503
Query: 121 KARQPPGPGAGDTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNINALPD 180
KARQPPGPGAGDTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNINALPD
Sbjct: 504 KARQPPGPGAGDTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNINALPD 563
Query: 181 VSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSA 240
VSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSA
Sbjct: 564 VSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSA 623
Query: 241 PQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRV 300
PQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRV
Sbjct: 624 PQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRV 683
Query: 301 QSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQ 360
QSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQ
Sbjct: 684 QSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQ 743
Query: 361 TRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGA 420
TRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGA
Sbjct: 744 TRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGA 803
Query: 421 NKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHV 480
NKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHV
Sbjct: 804 NKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHV 863
Query: 481 ILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFNVML 524
ILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFNVML
Sbjct: 864 ILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFNVML 907
Score = 35.0 bits (79), Expect = 0.17
Identities = 24/60 (40%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 442 TLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARII 501
+LG+ I GGA + I + G A G LKVG ILEVNG + H EA R++
Sbjct: 289 SLGLTIRGGAEYGLGI-YITGVDPGSEAEGSG-LKVGDQILEVNGRSFLNILHDEAVRLL 346
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 51.2 bits (121), Expect = 2e-06
Identities = 39/141 (27%), Positives = 65/141 (46%), Gaps = 3/141 (2%)
Query: 366 TLSHLSDSGQTLSEDSGVDAGEAEASAPG-RGRQSVSTKSRSSKELPRNERPTDGANKPP 424
T+ + Q + +G +GE + S+ QS S + S + R+ P A+ P
Sbjct: 1559 TIHAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPA 1618
Query: 425 G--LLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVIL 482
++ T + + K LG++I GG++T I + G+A G+L G IL
Sbjct: 1619 TCPIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQIL 1678
Query: 483 EVNGLTLRGKEHREAARIIAE 503
EVNG+ LR H EA ++ +
Sbjct: 1679 EVNGIDLRKATHDEAINVLRQ 1699
Score = 43.1 bits (100), Expect = 6e-04
Identities = 23/77 (29%), Positives = 42/77 (54%)
Query: 425 GLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEV 484
G L ++ ++K + LG+++ G + + IV I G+A G+L++ +LE+
Sbjct: 1342 GTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGIDPNGAAGKDGRLQIADELLEI 1401
Query: 485 NGLTLRGKEHREAARII 501
NG L G+ H+ A+ II
Sbjct: 1402 NGQILYGRSHQNASSII 1418
Score = 37.7 bits (86), Expect = 0.026
Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 429 PTSTLVRVKKSAATLGIAIEGG-ANTRQPLPRIV-TIQRGGSAHNCGQLKVGHVILEVNG 486
P + +++ LG +I GG + LP V T+ G+A G+LK G I+ VNG
Sbjct: 1954 PQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNG 2013
Query: 487 LTLRGKEHREAARII 501
+L G H EA I+
Sbjct: 2014 QSLEGVTHEEAVAIL 2028
Score = 34.7 bits (78), Expect = 0.22
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 10/64 (15%)
Query: 443 LGIAIE---GGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAAR 499
LGI++E G R LP G + G+L G +LEVNG+TL G+ H++
Sbjct: 565 LGISLEATVGHHFIRSVLPE-------GPVGHSGKLFSGDELLEVNGITLLGENHQDVVN 617
Query: 500 IIAE 503
I+ E
Sbjct: 618 ILKE 621
Score = 32.7 bits (73), Expect = 0.83
Identities = 18/77 (23%), Positives = 40/77 (51%), Gaps = 3/77 (3%)
Query: 434 VRVKKSAATLGIAIEGGANTRQPLPR---IVTIQRGGSAHNCGQLKVGHVILEVNGLTLR 490
V + K+ LGI I G ++ P + +I + + + G++++G I+ V+G L+
Sbjct: 378 VELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQ 437
Query: 491 GKEHREAARIIAEAFKT 507
G +++A ++ +T
Sbjct: 438 GFTNQQAVEVLRHTGQT 454
Score = 30.0 bits (66), Expect = 5.4
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Query: 430 TSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTL 489
T T+ KK LG++I G N + I +GG A G+L G IL VNG +
Sbjct: 1723 TLTIELQKKPGKGLGLSIVGKRNDTGVF--VSDIVKGGIADADGRLMQGDQILMVNGEDV 1780
Query: 490 RGKEHREAARII 501
R A ++
Sbjct: 1781 RNATQEAVAALL 1792
>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 50.1 bits (118), Expect = 5e-06
Identities = 69/304 (22%), Positives = 111/304 (36%), Gaps = 43/304 (14%)
Query: 121 KARQPPGPGAG----DTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNIN 176
+ + PP P + + + D SS + T T T N+
Sbjct: 71 RPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVT 130
Query: 177 ALPD----VSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPS 232
LP +S + +TS +++ P+ P P D P P SS P
Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAP----QDTTAAPPTPSATTPAPPSSSAPP 186
Query: 233 CSGTVFSAPQ--NRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVN 290
+ P ++PP+ +AP P T++A P + +PA PSS P + A
Sbjct: 187 ETTAAPPTPSATTQAPPSSSAP-PETTAAPPTPPA-----TTPAPPSSSAPPETTAA--- 237
Query: 291 QHPIGPFPRVQSPPHLKSPSAEATVA-----GGCLLPPSPSGHPDQTGTNQHFVMVEVHR 345
P P +P L S + T A L PS + P +T
Sbjct: 238 ----PPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPA 293
Query: 346 PDSEPDVNEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSR 405
P S P PQ TA+ ++ + S TL+ D+ E A+ + SV+T++
Sbjct: 294 PPSSP-------APQETTAAPITTPNSSPTTLAPDT----SETSAAPTHQTTTSVTTQTT 342
Query: 406 SSKE 409
++K+
Sbjct: 343 TTKQ 346
>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 50.1 bits (118), Expect = 5e-06
Identities = 69/304 (22%), Positives = 111/304 (36%), Gaps = 43/304 (14%)
Query: 121 KARQPPGPGAG----DTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNIN 176
+ + PP P + + + D SS + T T T N+
Sbjct: 71 RPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVT 130
Query: 177 ALPD----VSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPS 232
LP +S + +TS +++ P+ P P D P P SS P
Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAP----QDTTAAPPTPSATTPAPPSSSAPP 186
Query: 233 CSGTVFSAPQ--NRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVN 290
+ P ++PP+ +AP P T++A P + +PA PSS P + A
Sbjct: 187 ETTAAPPTPSATTQAPPSSSAP-PETTAAPPTPPA-----TTPAPPSSSAPPETTAA--- 237
Query: 291 QHPIGPFPRVQSPPHLKSPSAEATVA-----GGCLLPPSPSGHPDQTGTNQHFVMVEVHR 345
P P +P L S + T A L PS + P +T
Sbjct: 238 ----PPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPA 293
Query: 346 PDSEPDVNEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSR 405
P S P PQ TA+ ++ + S TL+ D+ E A+ + SV+T++
Sbjct: 294 PPSSP-------APQETTAAPITTPNSSPTTLAPDT----SETSAAPTHQTTTSVTTQTT 342
Query: 406 SSKE 409
++K+
Sbjct: 343 TTKQ 346
>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 50.1 bits (118), Expect = 5e-06
Identities = 69/304 (22%), Positives = 111/304 (36%), Gaps = 43/304 (14%)
Query: 121 KARQPPGPGAG----DTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNIN 176
+ + PP P + + + D SS + T T T N+
Sbjct: 71 RPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVT 130
Query: 177 ALPD----VSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPS 232
LP +S + +TS +++ P+ P P D P P SS P
Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAP----QDTTAAPPTPSATTPAPPSSSAPP 186
Query: 233 CSGTVFSAPQ--NRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVN 290
+ P ++PP+ +AP P T++A P + +PA PSS P + A
Sbjct: 187 ETTAAPPTPSATTQAPPSSSAP-PETTAAPPTPPA-----TTPAPPSSSAPPETTAA--- 237
Query: 291 QHPIGPFPRVQSPPHLKSPSAEATVA-----GGCLLPPSPSGHPDQTGTNQHFVMVEVHR 345
P P +P L S + T A L PS + P +T
Sbjct: 238 ----PPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPA 293
Query: 346 PDSEPDVNEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSR 405
P S P PQ TA+ ++ + S TL+ D+ E A+ + SV+T++
Sbjct: 294 PPSSP-------APQETTAAPITTPNSSPTTLAPDT----SETSAAPTHQTTTSVTTQTT 342
Query: 406 SSKE 409
++K+
Sbjct: 343 TTKQ 346
>gi|9966877 golgi associated PDZ and coiled-coil motif containing
isoform a [Homo sapiens]
Length = 462
Score = 50.1 bits (118), Expect = 5e-06
Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 418 DGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKV 477
D K G+ P ++ +K+ LGI+I GG P+ I I G A CG L V
Sbjct: 275 DSLKKSQGV-GPIRKVLLLKEDHEGLGISITGGKEHGVPI-LISEIHPGQPADRCGGLHV 332
Query: 478 GHVILEVNGLTLRGKEHREAARIIAE 503
G IL VNG+ LR +H+EA I+++
Sbjct: 333 GDAILAVNGVNLRDTKHKEAVTILSQ 358
>gi|62868213 golgi associated PDZ and coiled-coil motif containing
isoform b [Homo sapiens]
Length = 454
Score = 50.1 bits (118), Expect = 5e-06
Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 418 DGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKV 477
D K G+ P ++ +K+ LGI+I GG P+ I I G A CG L V
Sbjct: 267 DSLKKSQGV-GPIRKVLLLKEDHEGLGISITGGKEHGVPI-LISEIHPGQPADRCGGLHV 324
Query: 478 GHVILEVNGLTLRGKEHREAARIIAE 503
G IL VNG+ LR +H+EA I+++
Sbjct: 325 GDAILAVNGVNLRDTKHKEAVTILSQ 350
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 49.3 bits (116), Expect = 9e-06
Identities = 51/228 (22%), Positives = 81/228 (35%), Gaps = 17/228 (7%)
Query: 226 PPSSMPSCSGTVFSAPQNRSPPAGTAPTP--GTSSAQDLPSSPIYASVSPANPSSKRPLD 283
PP P+ P+ + PA PTP TS A +P+ S + A P+ + P
Sbjct: 1034 PPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1093
Query: 284 AHLAL-VNQHPIGPFPRVQSPPHLKSPSA-------EATVAGGCLLPPSPSGHPDQTGTN 335
A+ + P P V +P SP+A A+ A P P+ T
Sbjct: 1094 PAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTP 1153
Query: 336 QHFVMVEVHRPDSEPDVNEVRALPQ-------TRTASTLSHLSDSGQTLSEDSGVDAGEA 388
+ V P E + A+P +TL + ++ + + A
Sbjct: 1154 EESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLE 1213
Query: 389 EASAPGRGRQSVSTKSRSSKELPRNERPTDGANKPPGLLEPTSTLVRV 436
E ++P + + + + E PT A P L EPTS+ V
Sbjct: 1214 EFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAV 1261
Score = 33.5 bits (75), Expect = 0.49
Identities = 51/238 (21%), Positives = 80/238 (33%), Gaps = 15/238 (6%)
Query: 231 PSCSGTVFSAPQNRSPPAGTAPTP--GTSSAQDLPSSPIYASVSPANPSSKRPLDAHLAL 288
P + S P+ + PA PTP TS A +P+ S + A P + P A+
Sbjct: 987 PDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAV 1046
Query: 289 -VNQHPIGPFPRVQSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPD 347
+ P P V +P SP+A P P+ T + P
Sbjct: 1047 PTPEEPTSPAAAVPTPEEPTSPAAAVPT------PEEPTSPAAAVPTPEEPTSPAAAVPT 1100
Query: 348 SEPDVNEVRALP-QTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRS 406
E + A+P AS + + + S + V E E + P + + +
Sbjct: 1101 PEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPE-EPAFPAPAVPTPEESASA 1159
Query: 407 SKELPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQ 464
+ +P E A P E S V ATL A+ P + T++
Sbjct: 1160 AVAVPTPEESASPAAAVPTPAESASFAAVV----ATLEEPTSPAASVPTPAAMVATLE 1213
Score = 32.7 bits (73), Expect = 0.83
Identities = 38/159 (23%), Positives = 55/159 (34%), Gaps = 39/159 (24%)
Query: 226 PPSSMPSCSGTVFSAPQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAH 285
P P+ S P+ S PA + PTP ++ P++ + PA+P++ P
Sbjct: 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPAS---PAAAVSNLEEPASPAAAVPT--- 1302
Query: 286 LALVNQHPIGPFPRVQSPPHLKSPSAEATVAGGCLLPP----SPSGHPDQTGTNQHFVMV 341
P V + P P+ E +PP SP G P F+ V
Sbjct: 1303 ------------PEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVP--------FLGV 1342
Query: 342 EVHRPDSEPDVNEVRALPQTRTASTLSHLSDSGQTLSED 380
H DS P E L S +G + ED
Sbjct: 1343 SAH-TDSVPISEE--------GTPVLEEASSTGMWIKED 1372
Score = 30.4 bits (67), Expect = 4.1
Identities = 50/258 (19%), Positives = 88/258 (34%), Gaps = 27/258 (10%)
Query: 239 SAPQNRSPPAGTAPTPGTSSAQDLPSSP------IYASVSPANPSSK---RPLDAHLAL- 288
SAP+ + PA T P ++A SSP + A+++ S+ P A LA+
Sbjct: 902 SAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAIT 961
Query: 289 --------VNQHPIGPFPRVQSPP-------HLKSPSAEATVAGGCLLPPSPSGHPDQTG 333
+ P+ P V +P + +P A+ A P P+
Sbjct: 962 VPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP 1021
Query: 334 TNQHFVMVEVHRPDSEPDVNEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAP 393
T + P E + A+P ++ + + + + + E ++P
Sbjct: 1022 TPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1081
Query: 394 GRGRQSVSTKSRSSKELPRNERPTDGANKPPGLLEPTS--TLVRVKKSAATLGIAIEGGA 451
+ + + +P E PT A P EP S V + A+ A+
Sbjct: 1082 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPE 1141
Query: 452 NTRQPLPRIVTIQRGGSA 469
P P + T + SA
Sbjct: 1142 EPAFPAPAVPTPEESASA 1159
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 49.3 bits (116), Expect = 9e-06
Identities = 101/440 (22%), Positives = 157/440 (35%), Gaps = 78/440 (17%)
Query: 114 RREIESMKARQPPGPGAGDTYSMVSYSDTGSSTGSHGTSTTVSS-----ARNTLDLEETG 168
+ E+ + + GPGAGD S G+ G+H S + R + L
Sbjct: 2350 KEEVFRLPQEEEEGPGAGDE------SSCGTGGGTHRRSKKAKAPERPGTRVSERLRGAR 2403
Query: 169 EAVQGNINALPDVSVDDVRSTS---------QGLSSFKPLPRPPPLAQ------------ 207
QG N P +S RST+ + + P PRP P +
Sbjct: 2404 AETQG-ANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPV 2462
Query: 208 GNDLPLGQPRKLGREDLQ------PPSSMPSCSGTVFSAPQNRSPPAGTAPTPGTSSAQD 261
+P+ P + + PPS +P CS + P +PP P P +
Sbjct: 2463 SAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPP-AQTCLV 2521
Query: 262 LPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRVQ-------SPPHLKSPSAEAT 314
PSSP+ P+ P S A V P+G P + SP L+ S ++
Sbjct: 2522 TPSSPLLLG-PPSVPIS--------ASVTNLPLGLRPEAELCAQALASPESLELASVASS 2572
Query: 315 VAGGCLLPPSPSGHP---DQTGTNQHFVMVEVHRPD------SEPDVNEVRALPQTRTAS 365
L P P + ++ + + P S P+ E A P + +
Sbjct: 2573 ETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEA-PDSAEGT 2631
Query: 366 TLSHLSDSGQ---TLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGANK 422
TL+ L + + +SE +G++ + AS Q R+S+EL + PT K
Sbjct: 2632 TLTVLPEGEELPLCVSESNGLELPPSAAS--DEPLQEPLEADRTSEELTEAKTPTSSPEK 2689
Query: 423 PPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRI---VTIQRGGSAHNCGQLKVGH 479
P L+ SA + + EG + R P R V I RG GQ
Sbjct: 2690 PQELVTAEVAAPSTSSSATS---SPEGPSPARPPRRRTSADVEI-RGQGTGRPGQPPGPK 2745
Query: 480 VILEVNGLTLRGKEHREAAR 499
V+ ++ G + E +E R
Sbjct: 2746 VLRKLPGRLVTVVEEKELVR 2765
Score = 35.4 bits (80), Expect = 0.13
Identities = 65/245 (26%), Positives = 91/245 (37%), Gaps = 36/245 (14%)
Query: 206 AQGNDLPLGQPRKLGREDLQPPSSMPSCSGT--VFSAPQNRSPPAGTAPTPGTSSAQDLP 263
AQ L +GQPR L R + + S G + S P + + APTPG + LP
Sbjct: 1221 AQVRQLAVGQPRPLQRNVVH----LVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLP 1276
Query: 264 SSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRVQSPPHLKSPSAEATVAGGCLLPP 323
SS S +PA PL A+ P V + +K +A G +PP
Sbjct: 1277 SST--PSTTPAPTGLSLPLAANQV--------PPTMVNNTGVVKIVVRQAPRDGLTPVPP 1326
Query: 324 -SPSGHPDQTG----TNQHFVMVEVHRPDSEPDVNEVRA-LPQTRTASTLSHLSDSGQTL 377
+P+ P +G N + P P + RA +P L L S
Sbjct: 1327 LAPAPRPPSSGLPAVLNPRPTLTPGRLP--TPTLGTARAPMPTPTLVRPLLKLVHS---- 1380
Query: 378 SEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELP-RNERPTDGANKPPGLLEPTSTLVRV 436
+ E ASAPG ++S+ LP P N P L P S+ V V
Sbjct: 1381 ------PSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSP-LASPVSSTVSV 1433
Query: 437 KKSAA 441
S++
Sbjct: 1434 PLSSS 1438
Score = 30.4 bits (67), Expect = 4.1
Identities = 39/127 (30%), Positives = 50/127 (39%), Gaps = 24/127 (18%)
Query: 224 LQPPSSMPSCSGTVFSAPQN---RSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKR 280
L PSS+P + + P + SP + T P +SS LP S +PA+
Sbjct: 1401 LHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSS---LPISVPTTLPAPASAPLTI 1457
Query: 281 PLDAHL-------ALVNQ--HPIGP-FPRVQSPPHL----KSPSAEATVAGGCLLPPSPS 326
P+ A L AL+ P+ P P PP L SPSA A G P S
Sbjct: 1458 PISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSS 1517
Query: 327 ----GHP 329
GHP
Sbjct: 1518 SQTPGHP 1524
>gi|5803177 basic beta 2 syntrophin [Homo sapiens]
Length = 540
Score = 48.9 bits (115), Expect = 1e-05
Identities = 45/146 (30%), Positives = 60/146 (41%), Gaps = 13/146 (8%)
Query: 373 SGQTLSEDSGVDAGEAEASA----------PGRGRQSVSTKSRSSKEL--PRNERPTDGA 420
SG++LS A E E + P G S S+ L P P G
Sbjct: 44 SGESLSLTGDAAAAELEPALGPAAAAFNGLPNGGGAGDSLPGSPSRGLGPPSPPAPPRGP 103
Query: 421 NKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHV 480
G P + VK+ A LGI+I+GG R P+ I I G +A L++G
Sbjct: 104 AGEAGASPPVRRVRVVKQEAGGLGISIKGGRENRMPI-LISKIFPGLAADQSRALRLGDA 162
Query: 481 ILEVNGLTLRGKEHREAARIIAEAFK 506
IL VNG LR H +A + + A K
Sbjct: 163 ILSVNGTDLRQATHDQAVQALKRAGK 188
>gi|112382257 InaD-like [Homo sapiens]
Length = 1801
Score = 48.5 bits (114), Expect = 1e-05
Identities = 54/183 (29%), Positives = 83/183 (45%), Gaps = 35/183 (19%)
Query: 348 SEPDVNEVRALPQTRTASTLSHLSDSGQT----LSEDSGVDAG-----EAEA---SAPGR 395
+E VN++ P +S+ S + D T ED V+ G E+E+ +
Sbjct: 1321 NEDAVNQMAVTPFPVPSSSPSSIEDQSGTEPISSEEDGSVEVGIKQLPESESFKLAVSQM 1380
Query: 396 GRQSVSTK-SRSSKELP----RNERPTD------GANKPPGLLEPTST--------LVRV 436
+Q TK S SS+E+P + TD G + P ++P + ++ +
Sbjct: 1381 KQQKYPTKVSFSSQEIPLAPASSYHSTDADFTGYGGFQAPLSVDPATCPIVPGQEMIIEI 1440
Query: 437 KKSAATLGIAIEGGANTRQPLPRIVT--IQRGGSAHNCGQLKVGHVILEVNGLTLRGKEH 494
K + LG++I GG +T PL IV + G+A G+L G ILEVNG+ LR H
Sbjct: 1441 SKGRSGLGLSIVGGKDT--PLNAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRNSSH 1498
Query: 495 REA 497
EA
Sbjct: 1499 EEA 1501
Score = 40.0 bits (92), Expect = 0.005
Identities = 40/138 (28%), Positives = 62/138 (44%), Gaps = 12/138 (8%)
Query: 373 SGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGANKPPGL-LEPTS 431
S +T S++S A +S S + + L +R +D + K G +EP +
Sbjct: 1621 SARTTSQNSQGSQQSAHSSC----HPSFAPVITGLQNLVGTKRVSDPSQKNSGTDMEPRT 1676
Query: 432 TLVRVKKSAATLGIAIEGGANTRQPLPRI----VTIQRGGSAHNCGQLKVGHVILEVNGL 487
+ + S A LGI+I GG + PL I IQ G A +LKVG I+ +NG
Sbjct: 1677 VEINRELSDA-LGISIAGGRGS--PLGDIPVFIAMIQASGVAARTQKLKVGDRIVSINGQ 1733
Query: 488 TLRGKEHREAARIIAEAF 505
L G H + ++ A+
Sbjct: 1734 PLDGLSHADVVNLLKNAY 1751
Score = 39.3 bits (90), Expect = 0.009
Identities = 20/72 (27%), Positives = 39/72 (54%)
Query: 433 LVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGK 492
++ ++K LG+++ G + + +V I G A G++++G +LE+N L G+
Sbjct: 1239 IIELEKDKNGLGLSLAGNKDRSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGR 1298
Query: 493 EHREAARIIAEA 504
H+ A+ II A
Sbjct: 1299 SHQNASAIIKTA 1310
Score = 33.5 bits (75), Expect = 0.49
Identities = 18/44 (40%), Positives = 23/44 (52%)
Query: 460 IVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAE 503
I +I GG G L+ +LEVNG+ L GK REA + E
Sbjct: 583 ISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKE 626
Score = 32.0 bits (71), Expect = 1.4
Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 8/71 (11%)
Query: 442 TLGIAIEGGANTRQPLPR--------IVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKE 493
+LGI+I GG + L I + A LK G ILEV+G+ L+
Sbjct: 1078 SLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKILEVSGVDLQNAS 1137
Query: 494 HREAARIIAEA 504
H EA I A
Sbjct: 1138 HSEAVEAIKNA 1148
Score = 31.6 bits (70), Expect = 1.9
Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 437 KKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHRE 496
KK+ LG++I G N I I +GG+A G+L G IL VNG +R
Sbjct: 1538 KKAGRGLGLSIVGKRNGSGVF--ISDIVKGGAADLDGRLIQGDQILSVNGEDMRNASQET 1595
Query: 497 AARII 501
A I+
Sbjct: 1596 VATIL 1600
>gi|87196343 PDZ domain containing 2 [Homo sapiens]
Length = 2839
Score = 48.5 bits (114), Expect = 1e-05
Identities = 63/215 (29%), Positives = 92/215 (42%), Gaps = 33/215 (15%)
Query: 297 FPRVQSPPHLKSPSAEATVAGGCLLPPSPSGH----PDQTGTNQHFVMVEVHRPDSEPDV 352
F + PP K+P E+ + GC + PS PD N H +E + PDS +V
Sbjct: 219 FGVISRPPANKAPE-ESKGSAGCEVSSDPSTELENGPDPELGNGHVFQLE-NGPDSLKEV 276
Query: 353 NEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPR 412
A P HL S D G + + AP + + K R SK
Sbjct: 277 ----AGP---------HLERS----EVDRGTEHRIPKTDAP---LTTSNDKRRFSKGGKT 316
Query: 413 NERPTDG-ANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANT-RQPLPRIVT-IQRGGSA 469
+ + +D A + G + L K + LGI + GG + R P +VT ++ GG+A
Sbjct: 317 DFQSSDCLAREEVGRIWKMELL----KESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAA 372
Query: 470 HNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEA 504
H G+L +G +L +NG L G H EA I+ A
Sbjct: 373 HRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSA 407
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/162 (27%), Positives = 71/162 (43%), Gaps = 19/162 (11%)
Query: 359 PQTRTASTLSHLSDSGQTLSE-----DSGVDAGEAEASAPGRGR-QSV--STKSRSSKEL 410
P+T A T S SD+G+ + V+ + SA + R QSV S S+S+
Sbjct: 2546 PKTSAAETPSSASDTGEAAQDLPFRRSWSVNLDQLLVSAGDQQRLQSVLSSVGSKSTILT 2605
Query: 411 PRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQR---GG 467
E N+ E +V +K + LG ++ GG + P+ +T+ R G
Sbjct: 2606 LIQEAKAQSENE-----EDVCFIVLNRKEGSGLGFSVAGGTDVE---PKSITVHRVFSQG 2657
Query: 468 SAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKTKD 509
+A G + G +L VNG +L G H +++ +A KD
Sbjct: 2658 AASQEGTMNRGDFLLSVNGASLAGLAHGNVLKVLHQAQLHKD 2699
Score = 39.3 bits (90), Expect = 0.009
Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 4/71 (5%)
Query: 434 VRVKKSAATLGIAIEGGANTRQ---PLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLR 490
V V K++A LG++++GG ++ PL I + +GG+A G ++ G IL +NG L
Sbjct: 2751 VEVLKTSAGLGLSLDGGKSSVTGDGPLV-IKRVYKGGAAEQAGIIEAGDEILAINGKPLV 2809
Query: 491 GKEHREAARII 501
G H +A I+
Sbjct: 2810 GLMHFDAWNIM 2820
Score = 37.4 bits (85), Expect = 0.034
Identities = 45/162 (27%), Positives = 70/162 (43%), Gaps = 24/162 (14%)
Query: 343 VHRPDSEPDVNEVRAL---PQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQS 399
VHR +S + NE+ P+ R + +S G+ S +D+ A Q
Sbjct: 509 VHRLESVEEYNELMVRNGDPRIR----MLEVSRDGRKHSLPQLLDSSSAS--------QE 556
Query: 400 VSTKSRSSKELPRNERPTDGANKPPGLLEPT--STLVRVKKSAATLGIAIEGGANTRQPL 457
+S++ L T P L+ P+ S + K+ LG +I GG + +
Sbjct: 557 YHIVKKSTRSLS-----TTQVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQ 611
Query: 458 PRIV--TIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREA 497
I TI GSA G+LK G IL+VNG+ ++G +EA
Sbjct: 612 MGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEA 653
>gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo
sapiens]
Length = 817
Score = 47.4 bits (111), Expect = 3e-05
Identities = 87/356 (24%), Positives = 129/356 (36%), Gaps = 87/356 (24%)
Query: 196 FKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSAPQNRSPPAGTAPTP- 254
F+P P PPP G D P + R P P PQ+R PA P P
Sbjct: 251 FQPPPPPPPAPSG-DAPAEKERC-------PAGQQP---------PQHRVAPARPPPKPR 293
Query: 255 -------------GTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVN-------QHPI 294
G S A+ P I A V+ H AL N P
Sbjct: 294 EVRKIKPVEVEESGESEAESAPGEVIQAEVT-----------VHAALENGSTVATAASPA 342
Query: 295 GPFPRVQSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNE 354
P+ Q+ P K +A A G +P P++ ++ SE D+ +
Sbjct: 343 PEEPKAQAAPE-KEAAAVAPPERGVGNGRAPDVAPEEVDESKK-------EDFSEADLVD 394
Query: 355 VRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASA---PGRGRQSVSTKSR------ 405
V A S S L + + ED G E E+ PG + SR
Sbjct: 395 VSAYSGLGEDSAGSALEEDDEDDEED-GEPPYEPESGCVEIPGLSEEEDPAPSRKIHFST 453
Query: 406 ---------SSKELPRNERPTD--GANKPPGLLEPTSTL----VRVKKSAATLGIAIEG- 449
S+++ R D A+ L + L V ++K + LGI+I G
Sbjct: 454 APIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGM 513
Query: 450 GANTRQPLPR----IVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARII 501
GA L + + T+ GG+AH G+++V +++EV+G +L G AA ++
Sbjct: 514 GAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVL 569
>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
Length = 1332
Score = 46.2 bits (108), Expect = 7e-05
Identities = 64/282 (22%), Positives = 106/282 (37%), Gaps = 26/282 (9%)
Query: 245 SPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFP--RVQS 302
SP A A PG S + P ++ P R L A +Q P+ P R +S
Sbjct: 908 SPAASEARDPGVSESPPPGRQPNQKTLPPGPDPLLRLLSTQ-AEESQGPVLKMPSQRARS 966
Query: 303 PPHLKSPSAE--------------------ATVAGGCLLPPSPSGHPDQTGTNQHFVMVE 342
P +S S E A + LP S S +
Sbjct: 967 FPLTRSQSCETKLLDEKTSKLYSISSQVSSAVMKSLLCLPSSISCAQTPCIPKEGASPTS 1026
Query: 343 VHRPDSEPDVNEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVST 402
DS + + + T + LS L + + L+E D G+ + G+ S+ +
Sbjct: 1027 SSNEDSAANGSAETSALDTGFSLNLSELREYTEGLTEAKEDDDGDHSSLQSGQSVISLLS 1086
Query: 403 KSRSSKELPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVT 462
S K+L + D A L+ + K+ A LG ++ GGA+ + +
Sbjct: 1087 -SEELKKLIEEVKVLDEATLKQ--LDGIHVTILHKEEGAGLGFSLAGGADLENKVITVHR 1143
Query: 463 IQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEA 504
+ G A G ++ G+ +L +NG +L+G H +A I+ +A
Sbjct: 1144 VFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQA 1185
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/141 (30%), Positives = 71/141 (50%), Gaps = 21/141 (14%)
Query: 370 LSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGANKPPGLLEP 429
L + ++LS+ AG+A + S T+S S+ +L + P G L+
Sbjct: 169 LCSNRKSLSQQLDCPAGKAAGT-------SRPTRSLSTAQLVQ----------PSGGLQA 211
Query: 430 T--STLVRVKKSAATLGIAIEGGANTRQ-PLPRIV-TIQRGGSAHNCGQLKVGHVILEVN 485
+ S +V +K A LG +I GG ++ P+ V TI GG+A G+L+ G ILE+N
Sbjct: 212 SVISNIVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKTIFAGGAAAADGRLQEGDEILELN 271
Query: 486 GLTLRGKEHREAARIIAEAFK 506
G ++ G H++A + +A K
Sbjct: 272 GESMAGLTHQDALQKFKQAKK 292
>gi|27262655 interleukin 16 isoform 1 precursor [Homo sapiens]
Length = 631
Score = 46.2 bits (108), Expect = 7e-05
Identities = 64/282 (22%), Positives = 106/282 (37%), Gaps = 26/282 (9%)
Query: 245 SPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFP--RVQS 302
SP A A PG S + P ++ P R L A +Q P+ P R +S
Sbjct: 207 SPAASEARDPGVSESPPPGRQPNQKTLPPGPDPLLRLLSTQ-AEESQGPVLKMPSQRARS 265
Query: 303 PPHLKSPSAE--------------------ATVAGGCLLPPSPSGHPDQTGTNQHFVMVE 342
P +S S E A + LP S S +
Sbjct: 266 FPLTRSQSCETKLLDEKTSKLYSISSQVSSAVMKSLLCLPSSISCAQTPCIPKEGASPTS 325
Query: 343 VHRPDSEPDVNEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVST 402
DS + + + T + LS L + + L+E D G+ + G+ S+ +
Sbjct: 326 SSNEDSAANGSAETSALDTGFSLNLSELREYTEGLTEAKEDDDGDHSSLQSGQSVISLLS 385
Query: 403 KSRSSKELPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVT 462
S K+L + D A L+ + K+ A LG ++ GGA+ + +
Sbjct: 386 -SEELKKLIEEVKVLDEATLKQ--LDGIHVTILHKEEGAGLGFSLAGGADLENKVITVHR 442
Query: 463 IQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEA 504
+ G A G ++ G+ +L +NG +L+G H +A I+ +A
Sbjct: 443 VFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQA 484
>gi|223890252 glutamate receptor interacting protein 1 [Homo
sapiens]
Length = 1076
Score = 45.8 bits (107), Expect = 9e-05
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
Query: 398 QSVSTKSRSSKELPRNERPTDGA-----NKPPGLLEPTSTLVRVKKSAATLGIAIEGGAN 452
+S TKS S +P DGA P + ++ + +KK TLG+ + GG +
Sbjct: 20 ESPYTKSASQT------KPPDGALAVRRQSIPEEFKGSTVVELMKKEGTTLGLTVSGGID 73
Query: 453 TRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARII 501
+ PR+ +++GG A QL VG I VNG+ L H E ++
Sbjct: 74 -KDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLL 121
Score = 41.6 bits (96), Expect = 0.002
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 8/89 (8%)
Query: 423 PPGLLEPTSTLVR-----VKKSAATLGIAIEGGANTRQPLPR---IVTIQRGGSAHNCGQ 474
PP ++ +S + R + K T G I GGA+ + R I ++ GG A G
Sbjct: 137 PPVSVQGSSVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGT 196
Query: 475 LKVGHVILEVNGLTLRGKEHREAARIIAE 503
+K G +L V+G+ L G H EA I+ +
Sbjct: 197 IKPGDRLLSVDGIRLLGTTHAEAMSILKQ 225
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
Query: 434 VRVKKSAATLGIAIEGGANTRQPLPRIV--TIQRGGSAHNCGQLKVGHVILEVNGLTLRG 491
V +K+ LGI I G T +P I+ ++ +GG A G + +G IL +N +L+G
Sbjct: 622 VELKRYGGPLGITISG---TEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKG 678
Query: 492 KEHREAARIIAEAFKT 507
K EA ++ A +T
Sbjct: 679 KPLSEAIHLLQMAGET 694
Score = 34.3 bits (77), Expect = 0.29
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 430 TSTLVRVKKSAATLGIAIEGGANTRQPL---PRIVTIQRGGSAHNCGQLKVGHVILEVNG 486
T+ +V GI ++G + L P I I+ A CG L++G ++ +NG
Sbjct: 418 TTEVVLTADPVTGFGIQLQGSVFATETLSSPPLISYIEADSPAERCGVLQIGDRVMAING 477
Query: 487 LTLRGKEHREAARIIAEA 504
+ EA++++ ++
Sbjct: 478 IPTEDSTFEEASQLLRDS 495
Score = 31.2 bits (69), Expect = 2.4
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Query: 433 LVRVKKS-AATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRG 491
LV V K+ A+LG+A+ + + I I+ A CG L VG IL ++G ++
Sbjct: 252 LVEVAKTPGASLGVALTTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEY 311
Query: 492 KEHREAARIIA 502
EA + +A
Sbjct: 312 CTLAEATQFLA 322
>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
Length = 780
Score = 45.8 bits (107), Expect = 9e-05
Identities = 67/259 (25%), Positives = 101/259 (38%), Gaps = 34/259 (13%)
Query: 151 TSTTVSSARNTLDLEETGEAVQGNINAL-----PDVSVDDVRSTSQGLSSFKPLPRPPPL 205
+ST +A L TG +V + ++ P+ D + L + + +P P
Sbjct: 205 SSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTP- 263
Query: 206 AQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVF--SAPQNRSPPAGTAPTPGTSSAQDLP 263
AQ +GQP QPP P G V SAP P A T P P ++AQ P
Sbjct: 264 AQPQSFSVGQP--------QPPP--PPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQ--P 311
Query: 264 SSPIYA-----SVSPANPSSKRPLDAHLALVNQ-HPIGPFPRVQSPPHLKSPSAEATVAG 317
S P A ++ P N + +P ++L Q P P Q P P + +
Sbjct: 312 SQPQGAGPGGQTLPPTNVTLAQPA---MSLPPQPGPAVGAPAAQQPQQFAYPQPQ--IPP 366
Query: 318 GCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQTRTASTLSHLSDSGQTL 377
G LLP PSG + QH ++ P ++P A P T + ++
Sbjct: 367 GHLLPVQPSGQSEY--LQQHVAGLQPPSP-AQPSSTGAAASPATAATLPVGTGQNASSVG 423
Query: 378 SEDSGVDAGEAEASAPGRG 396
++ G + +EA AP G
Sbjct: 424 AQLMGASSQPSEAMAPRTG 442
Score = 32.0 bits (71), Expect = 1.4
Identities = 43/155 (27%), Positives = 56/155 (36%), Gaps = 28/155 (18%)
Query: 249 GTAPTPGTSSAQDLPSSPIYASVS-PANPS---SKRPLDAHLA--LVNQHPIGPFPRVQS 302
G A TPGT S L + A+ + PAN S R + LA L P P
Sbjct: 76 GDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPG 135
Query: 303 PPHLKSPSAEATVAGGCLLPPS------------PSGHPDQTGTNQHFVMVEVHRPDSEP 350
P L SA A P + SG P + G + +E + DS+
Sbjct: 136 GPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRG---RWTCMEYYERDSDS 192
Query: 351 DVNEVRALPQTRTASTLSHLSDSGQTLSEDSGVDA 385
V TR+ + H S QT DSG+ A
Sbjct: 193 SV-------LTRSGDCIRHSSTFDQTAERDSGLGA 220
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 45.8 bits (107), Expect = 9e-05
Identities = 60/214 (28%), Positives = 72/214 (33%), Gaps = 31/214 (14%)
Query: 192 GLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSAPQNRSPPAGTA 251
G SS LP PL LP P R +PPS S S P + PP
Sbjct: 772 GPSSSPSLPHQAPLGDSPHLPSPHPT---RPPSRPPSRPQSVSRPPSEPPLHPCPPPQAP 828
Query: 252 PT-PGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRVQSPPHLKSPS 310
PT PG Q+ P AS +PA P++ P L +Q P GP P PHL S
Sbjct: 829 PTLPGIFVIQNQLGVPPPAS-NPA-PTAPGPPQPPLRPQSQPPEGPLP---PAPHLPPSS 883
Query: 311 AEATVAGG----------------CLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPD--- 351
+ VA PPS H T ++ E P P
Sbjct: 884 TSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTF 943
Query: 352 ---VNEVRALPQTRTASTLSHLSDSGQTLSEDSG 382
ALPQ + H SG L +G
Sbjct: 944 QMVTTPFPALPQPKALLERFHQVPSGIILQNKAG 977
Score = 42.4 bits (98), Expect = 0.001
Identities = 50/185 (27%), Positives = 69/185 (37%), Gaps = 24/185 (12%)
Query: 202 PPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSAPQNRSPPAGTAPTPGTSSAQD 261
PP P+ + LG Q P S S AP + P A PG SS+
Sbjct: 728 PPAQDPAPATPVAKGAGLGP---QAPDSQAS------PAPAPQIPAAAPLKGPGPSSSPS 778
Query: 262 LP------SSPIYASVSPANPSSKRPLDAHLAL--VNQHPIGPFPRVQSPPHLKSPSAEA 313
LP SP S P P S+ P ++ P+ P P Q+PP L
Sbjct: 779 LPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQ 838
Query: 314 TVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQTRTASTLSHLSDS 373
G + PP+ + P G Q + RP S+P + P +ST S ++ S
Sbjct: 839 NQLG--VPPPASNPAPTAPGPPQPPL-----RPQSQPPEGPLPPAPHLPPSSTSSAVASS 891
Query: 374 GQTLS 378
+T S
Sbjct: 892 SETSS 896
Score = 36.2 bits (82), Expect = 0.075
Identities = 38/141 (26%), Positives = 57/141 (40%), Gaps = 11/141 (7%)
Query: 198 PLPRPPPLAQGNDLPLGQPRKLGREDLQ---PPSSMPSCSGTVFSAPQNRSPPAGTAPTP 254
P P + + L + P++ ++ L P S+P+ + SAP PA P
Sbjct: 683 PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPA--SVIVSAPPPAQDPAPATPVA 740
Query: 255 GTSS----AQDLPSSPIYASVSPANPSSKRP-LDAHLALVNQHPIGPFPRVQSPPHLKSP 309
+ A D +SP A PA K P + +L +Q P+G P + SP + P
Sbjct: 741 KGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPP 800
Query: 310 SAEATVAGGCLLPPS-PSGHP 329
S + PPS P HP
Sbjct: 801 SRPPSRPQSVSRPPSEPPLHP 821
Score = 32.3 bits (72), Expect = 1.1
Identities = 53/228 (23%), Positives = 72/228 (31%), Gaps = 33/228 (14%)
Query: 207 QGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSAPQNRSPPAGTAPTPGTSSAQDLPSSP 266
Q P G + + P S + T Q +P A T + Q P +P
Sbjct: 569 QSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAP 628
Query: 267 IYASVSPANPSSKRPLDAHLALVNQHPIGPFPRVQSPPHLKSPSAEATVAGG---CLLPP 323
PA S+ PL Q P P P+ +PP +P +A +L
Sbjct: 629 ------PA-VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQ 681
Query: 324 SPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQTRTASTLS----HLSDSGQTL-- 377
PS P T M LPQ R+ LS HLS +
Sbjct: 682 PPSATPTAILTQDSLQMF----------------LPQERSQQPLSAEGPHLSVPASVIVS 725
Query: 378 SEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGANKPPG 425
+ D A A G G + S++S P + P K PG
Sbjct: 726 APPPAQDPAPATPVAKGAGLGPQAPDSQAS-PAPAPQIPAAAPLKGPG 772
>gi|11321640 basic beta 1 syntrophin [Homo sapiens]
Length = 538
Score = 45.8 bits (107), Expect = 9e-05
Identities = 46/161 (28%), Positives = 65/161 (40%), Gaps = 10/161 (6%)
Query: 355 VRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAP------GRGRQSVSTKSRSSK 408
+ L + R L +LS+ LS + G A +A G G
Sbjct: 26 LEVLVRDRWHKVLVNLSEDALVLSSEEGAAAYNGIGTATNGSFCRGAGAGHPGAGGAQPP 85
Query: 409 ELPRNERP--TDGANKPPGLLEPTSTLVRV-KKSAATLGIAIEGGANTRQPLPRIVTIQR 465
+ P R TD + P + V+V K+ LGI+I+GG + P+ I I +
Sbjct: 86 DSPAGVRTAFTDLPEQVPESISNQKRGVKVLKQELGGLGISIKGGKENKMPI-LISKIFK 144
Query: 466 GGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFK 506
G +A L VG IL VNG LR H EA + + A K
Sbjct: 145 GLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGK 185
>gi|24025688 ligand of numb-protein X 2 [Homo sapiens]
Length = 690
Score = 45.4 bits (106), Expect = 1e-04
Identities = 49/183 (26%), Positives = 79/183 (43%), Gaps = 18/183 (9%)
Query: 341 VEVHRPDSEPDVNEVR-ALPQTRTASTLSHL-SDSGQTLSEDSGVDAGEAEASAPGR--- 395
+E H + P + R AL + +T+ T + + +++G TL + +G + EA+ G
Sbjct: 129 LEAHLKNRCPGASHRRVALERRKTSRTQAEIENENGPTLLDPAGTLSPEADCLGTGAVPV 188
Query: 396 GRQSVSTKSRSSKELPRNERPT-------DGANKPPGLLEPTSTLVRVKKSAA--TLGIA 446
R S + E P + P D +P L E T + + +S LGI+
Sbjct: 189 ERHLTSASLSTWSEEPGLDNPAFEESAGADTTQQPLSLPEGEITTIEIHRSNPYIQLGIS 248
Query: 447 IEGGANTRQPLPRIVT--IQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEA 504
I GG T PL IV + R G G+L G IL+VN + H A ++++
Sbjct: 249 IVGGNET--PLINIVIQEVYRDGVIARDGRLLAGDQILQVNNYNISNVSHNYARAVLSQP 306
Query: 505 FKT 507
T
Sbjct: 307 CNT 309
Score = 36.6 bits (83), Expect = 0.058
Identities = 40/145 (27%), Positives = 62/145 (42%), Gaps = 19/145 (13%)
Query: 377 LSEDSGVDAGEAEASAPGRGR-----QSVSTKSRSSKELPR--NERPTDGANKP------ 423
LS V +A A++P Q V +++++E P +E D + P
Sbjct: 530 LSHSEAVAMLKASAASPAVALKALEVQIVEEATQNAEEQPSTFSENEYDASWSPSWVMWL 589
Query: 424 --PGLLEPTSTLVRVKKSAATLGIAIEGGA---NTRQPLPRIVTIQRGGSAHNCGQLKVG 478
P L +V + + G +I GG +T QP I TI G A+ G+LK G
Sbjct: 590 GLPSTLHSCHDIVLRRSYLGSWGFSIVGGYEENHTNQPF-FIKTIVLGTPAYYDGRLKCG 648
Query: 479 HVILEVNGLTLRGKEHREAARIIAE 503
+I+ VNGL+ G H ++ E
Sbjct: 649 DMIVAVNGLSTVGMSHSALVPMLKE 673
Score = 35.4 bits (80), Expect = 0.13
Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 437 KKSAATLGIAIEGGANTRQ-PLPRIVT-IQRGGSAHNCGQLKVGHVILEVNGLTLRGKEH 494
K+ +LG+ + GG ++ LP VT + G G++K G V+L +NG+ L H
Sbjct: 473 KEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVLLNINGIDLTNLSH 532
Query: 495 REAARII 501
EA ++
Sbjct: 533 SEAVAML 539
>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
Length = 380
Score = 45.1 bits (105), Expect = 2e-04
Identities = 59/246 (23%), Positives = 85/246 (34%), Gaps = 21/246 (8%)
Query: 200 PRPPPLAQGNDLPLG-QPRKLGREDLQPPSSMPSCSGTVFSAPQNRSPPAGTAPTPGTSS 258
P PPP +P G P ++ ++ Q P V +A +PPAG P P
Sbjct: 118 PPPPPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPP 177
Query: 259 AQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRVQSP--PHLKSPSAEATVA 316
P P P P S P AH A P P P Q P +P A +A
Sbjct: 178 PPPGPPPP------PGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIA 231
Query: 317 GGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQTRTASTLSHLSDSGQT 376
G L S ++ E R + E+ A+ R +T G+
Sbjct: 232 GAKLRKVSKQ---EEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKAT-----QVGEK 283
Query: 377 LSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGANKPPGLLEPTST---- 432
+D + E EA P + ++S LPR + + P+S+
Sbjct: 284 TPKDESANQEEPEARVPAQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSD 343
Query: 433 LVRVKK 438
L RVK+
Sbjct: 344 LQRVKQ 349
>gi|66346708 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform b [Homo sapiens]
Length = 1256
Score = 45.1 bits (105), Expect = 2e-04
Identities = 48/164 (29%), Positives = 65/164 (39%), Gaps = 22/164 (13%)
Query: 344 HRPDSEPDVNEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTK 403
H + + E + PQ S + S SG T SG+ +G G G VST
Sbjct: 944 HSSNQPASLTEEKRTPQGSQNSLNTVSSGSGST----SGIGSGG------GGGSGVVSTV 993
Query: 404 SRSSKELPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTI 463
+ P + G N+ G + +S S G G A P +I I
Sbjct: 994 VQ-----PYDVEIRRGENEGFGFVIVSSV------SRPEAGTTFAGNACVAMP-HKIGRI 1041
Query: 464 QRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKT 507
G A CG+LKVG IL VNG ++ K H + +I EA T
Sbjct: 1042 IEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNT 1085
Score = 43.9 bits (102), Expect = 4e-04
Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 423 PPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVIL 482
P E V +++ A G ++ GG L ++ + G A CG++++G IL
Sbjct: 1142 PQATQEQDFYTVELERGAKGFGFSLRGGREYNMDL-YVLRLAEDGPAERCGKMRIGDEIL 1200
Query: 483 EVNGLTLRGKEHREAARII 501
E+NG T + +H A +I
Sbjct: 1201 EINGETTKNMKHSRAIELI 1219
>gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo
sapiens]
Length = 1287
Score = 45.1 bits (105), Expect = 2e-04
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 13/139 (9%)
Query: 365 STLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGANKPP 424
S LSH D + E +D ++ P R R +S LP + PP
Sbjct: 871 SLLSHTQDQDRNTEE---LDMAGVQSLVP-RLRHQLSF-------LPLKGAGSSCPPSPP 919
Query: 425 GLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIV--TIQRGGSAHNCGQLKVGHVIL 482
+ V + K TLG ++ GG NT P I +I GG A GQ+ G +L
Sbjct: 920 EISAGEIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLL 979
Query: 483 EVNGLTLRGKEHREAARII 501
+V+G+ L G H++A + +
Sbjct: 980 QVDGVILCGLTHKQAVQCL 998
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 434 VRVKKSAATLGIAI-----EGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLT 488
V++KK+A LG + E ++ + L RI + G A G + G +IL VNG +
Sbjct: 1058 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 1117
Query: 489 LRGKEHREAARIIAEA 504
G +E ++ A
Sbjct: 1118 TEGLIFQEVLHLLRGA 1133
>gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo
sapiens]
Length = 1309
Score = 45.1 bits (105), Expect = 2e-04
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 13/139 (9%)
Query: 365 STLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGANKPP 424
S LSH D + E +D ++ P R R +S LP + PP
Sbjct: 893 SLLSHTQDQDRNTEE---LDMAGVQSLVP-RLRHQLSF-------LPLKGAGSSCPPSPP 941
Query: 425 GLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIV--TIQRGGSAHNCGQLKVGHVIL 482
+ V + K TLG ++ GG NT P I +I GG A GQ+ G +L
Sbjct: 942 EISAGEIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLL 1001
Query: 483 EVNGLTLRGKEHREAARII 501
+V+G+ L G H++A + +
Sbjct: 1002 QVDGVILCGLTHKQAVQCL 1020
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 434 VRVKKSAATLGIAI-----EGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLT 488
V++KK+A LG + E ++ + L RI + G A G + G +IL VNG +
Sbjct: 1080 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 1139
Query: 489 LRGKEHREAARIIAEA 504
G +E ++ A
Sbjct: 1140 TEGLIFQEVLHLLRGA 1155
>gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]
Length = 739
Score = 44.3 bits (103), Expect = 3e-04
Identities = 60/254 (23%), Positives = 90/254 (35%), Gaps = 27/254 (10%)
Query: 177 ALPDVSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGT 236
A P VS +D + T+ + P P PP L P+ + S M +
Sbjct: 138 ATPQVSGEDTQPTTYAAEAQGPTPEPP---------LASPQT---SQMLVTSKMAAPEAP 185
Query: 237 VFSAPQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIG- 295
SA PA A T G SSA +P V AN S L + P G
Sbjct: 186 ATSAQSQTGSPAQEAATEGPSSACAFSQAPCAREVD-ANRPSTAFLGQNDVFDFTQPAGV 244
Query: 296 ---PFPRVQSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDV 352
FPR + P +P+ EA G P + SG P QTG + S +
Sbjct: 245 SGMAFPRPKRP----APAQEAATEG----PSAASGVP-QTGPGREVAATRPKTTKSGKAL 295
Query: 353 NEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPR 412
+ R + + + + ++ E G A A+ SA R +++ SK L
Sbjct: 296 AKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMG-GKRTKKSKHLDD 354
Query: 413 NERPTDGANKPPGL 426
++ + P +
Sbjct: 355 EYESSEEERETPAV 368
>gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
Length = 741
Score = 44.3 bits (103), Expect = 3e-04
Identities = 60/254 (23%), Positives = 90/254 (35%), Gaps = 27/254 (10%)
Query: 177 ALPDVSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGT 236
A P VS +D + T+ + P P PP L P+ + S M +
Sbjct: 138 ATPQVSGEDTQPTTYAAEAQGPTPEPP---------LASPQT---SQMLVTSKMAAPEAP 185
Query: 237 VFSAPQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIG- 295
SA PA A T G SSA +P V AN S L + P G
Sbjct: 186 ATSAQSQTGSPAQEAATEGPSSACAFSQAPCAREVD-ANRPSTAFLGQNDVFDFTQPAGV 244
Query: 296 ---PFPRVQSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDV 352
FPR + P +P+ EA G P + SG P QTG + S +
Sbjct: 245 SGMAFPRPKRP----APAQEAATEG----PSAASGVP-QTGPGREVAATRPKTTKSGKAL 295
Query: 353 NEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPR 412
+ R + + + + ++ E G A A+ SA R +++ SK L
Sbjct: 296 AKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMG-GKRTKKSKHLDD 354
Query: 413 NERPTDGANKPPGL 426
++ + P +
Sbjct: 355 EYESSEEERETPAV 368
>gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
Length = 741
Score = 44.3 bits (103), Expect = 3e-04
Identities = 60/254 (23%), Positives = 90/254 (35%), Gaps = 27/254 (10%)
Query: 177 ALPDVSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGT 236
A P VS +D + T+ + P P PP L P+ + S M +
Sbjct: 138 ATPQVSGEDTQPTTYAAEAQGPTPEPP---------LASPQT---SQMLVTSKMAAPEAP 185
Query: 237 VFSAPQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIG- 295
SA PA A T G SSA +P V AN S L + P G
Sbjct: 186 ATSAQSQTGSPAQEAATEGPSSACAFSQAPCAREVD-ANRPSTAFLGQNDVFDFTQPAGV 244
Query: 296 ---PFPRVQSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDV 352
FPR + P +P+ EA G P + SG P QTG + S +
Sbjct: 245 SGMAFPRPKRP----APAQEAATEG----PSAASGVP-QTGPGREVAATRPKTTKSGKAL 295
Query: 353 NEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPR 412
+ R + + + + ++ E G A A+ SA R +++ SK L
Sbjct: 296 AKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMG-GKRTKKSKHLDD 354
Query: 413 NERPTDGANKPPGL 426
++ + P +
Sbjct: 355 EYESSEEERETPAV 368
>gi|149274614 melanoma antigen family D, 4 [Homo sapiens]
Length = 739
Score = 44.3 bits (103), Expect = 3e-04
Identities = 60/254 (23%), Positives = 90/254 (35%), Gaps = 27/254 (10%)
Query: 177 ALPDVSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGT 236
A P VS +D + T+ + P P PP L P+ + S M +
Sbjct: 138 ATPQVSGEDTQPTTYAAEAQGPTPEPP---------LASPQT---SQMLVTSKMAAPEAP 185
Query: 237 VFSAPQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIG- 295
SA PA A T G SSA +P V AN S L + P G
Sbjct: 186 ATSAQSQTGSPAQEAATEGPSSACAFSQAPCAREVD-ANRPSTAFLGQNDVFDFTQPAGV 244
Query: 296 ---PFPRVQSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDV 352
FPR + P +P+ EA G P + SG P QTG + S +
Sbjct: 245 SGMAFPRPKRP----APAQEAATEG----PSAASGVP-QTGPGREVAATRPKTTKSGKAL 295
Query: 353 NEVRALPQTRTASTLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPR 412
+ R + + + + ++ E G A A+ SA R +++ SK L
Sbjct: 296 AKTRWVEPQNVVAAAAAKAKMATSIPEPEGAAAATAQHSAEPWARMG-GKRTKKSKHLDD 354
Query: 413 NERPTDGANKPPGL 426
++ + P +
Sbjct: 355 EYESSEEERETPAV 368
>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
isoform 3 [Homo sapiens]
Length = 2294
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/139 (23%), Positives = 66/139 (47%), Gaps = 12/139 (8%)
Query: 365 STLSHLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGANKPP 424
S ++ SD G + +++ + + + SV+T ++ + + + P KP
Sbjct: 1119 SDVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPP-----KPG 1173
Query: 425 GLLEPTSTLVRVKKSAATLGIAIEGGANT--RQPLPRIVTIQRGGSAHNCGQLKVGHVIL 482
+ E V + K+ +LGI++ GG NT R + + G+A + G++ G +L
Sbjct: 1174 DIFE-----VELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVL 1228
Query: 483 EVNGLTLRGKEHREAARII 501
VNG++L G H++A +
Sbjct: 1229 AVNGVSLEGATHKQAVETL 1247
Score = 31.6 bits (70), Expect = 1.9
Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Query: 434 VRVKKSAATLGIAIEGGANT-----RQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLT 488
V++ K+++ LG + N + R+ + G A G++ VG VIL+VNG +
Sbjct: 1311 VKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGAS 1370
Query: 489 LRGKEHRE 496
L+G +E
Sbjct: 1371 LKGLSQQE 1378
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,271,468
Number of Sequences: 37866
Number of extensions: 1293307
Number of successful extensions: 7624
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 705
Number of HSP's that attempted gapping in prelim test: 6097
Number of HSP's gapped (non-prelim): 1985
length of query: 524
length of database: 18,247,518
effective HSP length: 107
effective length of query: 417
effective length of database: 14,195,856
effective search space: 5919671952
effective search space used: 5919671952
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.