Search of human proteins with 140560919

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|140560919 myomesin 1 isoform a [Homo sapiens]
         (1685 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|140560919 myomesin 1 isoform a [Homo sapiens]                     3393   0.0  
gi|140560917 myomesin 1 isoform b [Homo sapiens]                     1723   0.0  
gi|156104903 myomesin 2 [Homo sapiens]                                862   0.0  
gi|155969693 myomesin family, member 3 [Homo sapiens]                 746   0.0  
gi|110349719 titin isoform N2-A [Homo sapiens]                        257   8e-68
gi|110349717 titin isoform novex-2 [Homo sapiens]                     257   8e-68
gi|110349713 titin isoform novex-1 [Homo sapiens]                     257   8e-68
gi|110349715 titin isoform N2-B [Homo sapiens]                        257   8e-68
gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens]     170   9e-42
gi|148839296 immunoglobulin-like and fibronectin type III domain...   132   4e-30
gi|46049110 myosin binding protein C, slow type isoform 4 [Homo ...   117   7e-26
gi|46049125 myosin binding protein C, slow type isoform 2 [Homo ...   117   7e-26
gi|45976288 myosin binding protein C, slow type isoform 1 [Homo ...   117   7e-26
gi|148596957 myosin binding protein C, cardiac [Homo sapiens]         115   3e-25
gi|109633039 protein tyrosine phosphatase, receptor type, F isof...   114   6e-25
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo...   114   1e-24
gi|119220552 sidekick 1 [Homo sapiens]                                114   1e-24
gi|109633041 protein tyrosine phosphatase, receptor type, F isof...   113   1e-24
gi|222352127 sidekick 2 [Homo sapiens]                                110   1e-23
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ...   110   1e-23
gi|133908641 myosin binding protein C, fast type [Homo sapiens]       110   1e-23
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo...   110   2e-23
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor...   108   4e-23
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ...   105   5e-22
gi|157311649 neogenin homolog 1 [Homo sapiens]                        105   5e-22
gi|46049119 myosin binding protein C, slow type isoform 3 [Homo ...   105   5e-22
gi|110431348 deleted in colorectal carcinoma [Homo sapiens]            96   3e-19
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo...    96   4e-19
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor...    96   4e-19
gi|205360934 fibronectin type III domain containing 3B [Homo sap...    95   5e-19

>gi|140560919 myomesin 1 isoform a [Homo sapiens]
          Length = 1685

 Score = 3393 bits (8798), Expect = 0.0
 Identities = 1685/1685 (100%), Positives = 1685/1685 (100%)

Query: 1    MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEA 60
            MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEA
Sbjct: 1    MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEA 60

Query: 61   FRRASASSSQQQASQHALSSEVSRKAASAYDYGSSHGLTDSSLLLDDYSSKLSPKPKRAK 120
            FRRASASSSQQQASQHALSSEVSRKAASAYDYGSSHGLTDSSLLLDDYSSKLSPKPKRAK
Sbjct: 61   FRRASASSSQQQASQHALSSEVSRKAASAYDYGSSHGLTDSSLLLDDYSSKLSPKPKRAK 120

Query: 121  HSLLSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITT 180
            HSLLSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITT
Sbjct: 121  HSLLSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITT 180

Query: 181  SKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKS 240
            SKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKS
Sbjct: 181  SKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKS 240

Query: 241  RKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSI 300
            RKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSI
Sbjct: 241  RKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSI 300

Query: 301  AGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGE 360
            AGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGE
Sbjct: 301  AGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGE 360

Query: 361  LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGE 420
            LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGE
Sbjct: 361  LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGE 420

Query: 421  TMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLY 480
            TMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLY
Sbjct: 421  TMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLY 480

Query: 481  TIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSP 540
            TIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSP
Sbjct: 481  TIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSP 540

Query: 541  ILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSE 600
            ILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSE
Sbjct: 541  ILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSE 600

Query: 601  PVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKP 660
            PVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKP
Sbjct: 601  PVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKP 660

Query: 661  PGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV 720
            PGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV
Sbjct: 661  PGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV 720

Query: 721  GEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGS 780
            GEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGS
Sbjct: 721  GEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGS 780

Query: 781  GKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVS 840
            GKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVS
Sbjct: 781  GKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVS 840

Query: 841  PDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVS 900
            PDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVS
Sbjct: 841  PDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVS 900

Query: 901  ETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKI 960
            ETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKI
Sbjct: 901  ETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKI 960

Query: 961  GGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLG 1020
            GGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLG
Sbjct: 961  GGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLG 1020

Query: 1021 APSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEA 1080
            APSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEA
Sbjct: 1021 APSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEA 1080

Query: 1081 KAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG 1140
            KAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG
Sbjct: 1081 KAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG 1140

Query: 1141 TKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDL 1200
            TKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDL
Sbjct: 1141 TKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDL 1200

Query: 1201 GMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQV 1260
            GMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQV
Sbjct: 1201 GMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQV 1260

Query: 1261 RFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQL 1320
            RFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQL
Sbjct: 1261 RFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQL 1320

Query: 1321 QDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKV 1380
            QDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKV
Sbjct: 1321 QDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKV 1380

Query: 1381 ANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSR 1440
            ANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSR
Sbjct: 1381 ANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSR 1440

Query: 1441 LKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIR 1500
            LKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIR
Sbjct: 1441 LKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIR 1500

Query: 1501 YSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR 1560
            YSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR
Sbjct: 1501 YSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR 1560

Query: 1561 LKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCN 1620
            LKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCN
Sbjct: 1561 LKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCN 1620

Query: 1621 LKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKG 1680
            LKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKG
Sbjct: 1621 LKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKG 1680

Query: 1681 GKKAK 1685
            GKKAK
Sbjct: 1681 GKKAK 1685


>gi|140560917 myomesin 1 isoform b [Homo sapiens]
          Length = 1589

 Score = 1723 bits (4462), Expect = 0.0
 Identities = 885/1039 (85%), Positives = 918/1039 (88%), Gaps = 24/1039 (2%)

Query: 1    MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEA 60
            MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEA
Sbjct: 1    MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEA 60

Query: 61   FRRASASSSQQQASQHALSSEVSRKAASAYDYGSSHGLTDSSLLLDDYSSKLSPKPKRAK 120
            FRRASASSSQQQASQHALSSEVSRKAASAYDYGSSHGLTDSSLLLDDYSSKLSPKPKRAK
Sbjct: 61   FRRASASSSQQQASQHALSSEVSRKAASAYDYGSSHGLTDSSLLLDDYSSKLSPKPKRAK 120

Query: 121  HSLLSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITT 180
            HSLLSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITT
Sbjct: 121  HSLLSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITT 180

Query: 181  SKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKS 240
            SKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKS
Sbjct: 181  SKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKS 240

Query: 241  RKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSI 300
            RKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSI
Sbjct: 241  RKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSI 300

Query: 301  AGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGE 360
            AGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGE
Sbjct: 301  AGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGE 360

Query: 361  LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGE 420
            LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGE
Sbjct: 361  LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGE 420

Query: 421  TMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLY 480
            TMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLY
Sbjct: 421  TMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLY 480

Query: 481  TIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSP 540
            TIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSP
Sbjct: 481  TIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSP 540

Query: 541  ILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSE 600
            ILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSE
Sbjct: 541  ILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSE 600

Query: 601  PVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKP 660
            PVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKP
Sbjct: 601  PVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKP 660

Query: 661  PGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV 720
            PGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV
Sbjct: 661  PGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV 720

Query: 721  GEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGS 780
            GEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGS
Sbjct: 721  GEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGS 780

Query: 781  GKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVS 840
            GKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAI     
Sbjct: 781  GKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSP 840

Query: 841  PDVCPALS-------------DEPGGLTASRGRVHEASPPTFQKDALLG--SKPNKPSLP 885
            P     L              D+ GG   +   V+        ++ + G   K  + ++ 
Sbjct: 841  PCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVN-------YREVIDGVPGKWREANVK 893

Query: 886  SSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLK-KKTDRAPPSPPCDITCLE 944
            + S+   +    K +   Q ++            + S+  K ++   A P PP  + C E
Sbjct: 894  AVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSE 953

Query: 945  SFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKEN 1004
              +DS+VL WK P   G   +TGY+V+ +E       +WR  N  A+     K+  LKE 
Sbjct: 954  VRKDSLVLQWKPPVHSGRTPVTGYFVDLKEA-KAKEDQWRGLNEAAIKNVYLKVRGLKEG 1012

Query: 1005 MVYQFQVAAMNMAGLGAPS 1023
            + Y F+V A+N AG+G PS
Sbjct: 1013 VSYVFRVRAINQAGVGKPS 1031



 Score = 1638 bits (4241), Expect = 0.0
 Identities = 853/1106 (77%), Positives = 905/1106 (81%), Gaps = 50/1106 (4%)

Query: 621  WTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAG 679
            ++  + V + +      P  P D+   EA + Y+++SWK P   G   I+ YF++KCE G
Sbjct: 493  YSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVG 552

Query: 680  TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDI- 738
            T++W + N + PVK  RF +  L EG+SY FRVR  N  G+G PS  +E     D  +  
Sbjct: 553  TDSWSQCN-DTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKA 611

Query: 739  -----PKAPGK-------------IIPSRNTDTSV--------VVSWEE-SKDAKELVGY 771
                 P AP               I+P   TD SV        V+SW+   +   E + Y
Sbjct: 612  RLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMY 671

Query: 772  YIEASVAGSGKWEPCNNN-PVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIE 830
            ++E   AG+  W+  N   PVK  RF    L  G+SY FRVR  N+AG+ E S+ +E   
Sbjct: 672  FVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTV 731

Query: 831  VKAAIGGGVSPD-VCPALSDEPGGLTASR---------GRVHEASPPTFQKDALLGSKPN 880
            V   +    +P  + P+ + +   + +           G   EAS     K     + P 
Sbjct: 732  VGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPV 791

Query: 881  KPS-LPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCD 939
            K S         GQ+ + +V       L+   Q         S+ ++ K   APPSPPCD
Sbjct: 792  KGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQD--------SEAIEVKAAIAPPSPPCD 843

Query: 940  ITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKIS 999
            ITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKIS
Sbjct: 844  ITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKIS 903

Query: 1000 NLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQW 1059
            NLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQW
Sbjct: 904  NLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQW 963

Query: 1060 KPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAIN 1119
            KPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAIN
Sbjct: 964  KPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAIN 1023

Query: 1120 QAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTE 1179
            QAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTE
Sbjct: 1024 QAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTE 1083

Query: 1180 DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEH 1239
            DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEH
Sbjct: 1084 DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEH 1143

Query: 1240 KFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTG 1299
            KFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTG
Sbjct: 1144 KFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTG 1203

Query: 1300 IIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPH 1359
            IIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPH
Sbjct: 1204 IIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPH 1263

Query: 1360 FVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFS 1419
            FVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFS
Sbjct: 1264 FVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFS 1323

Query: 1420 KKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYS 1479
            KKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYS
Sbjct: 1324 KKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYS 1383

Query: 1480 FVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTG 1539
            FVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTG
Sbjct: 1384 FVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTG 1443

Query: 1540 HQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGD 1599
            HQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGD
Sbjct: 1444 HQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGD 1503

Query: 1600 PPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDF 1659
            PPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDF
Sbjct: 1504 PPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDF 1563

Query: 1660 TVSVFIPEEEARMAALESLKGGKKAK 1685
            TVSVFIPEEEARMAALESLKGGKKAK
Sbjct: 1564 TVSVFIPEEEARMAALESLKGGKKAK 1589



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 40/97 (41%), Positives = 57/97 (58%), Gaps = 2/97 (2%)

Query: 510  PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFID--KCEVGTDSWSQCNDTPVKFA 567
            P  P  +KC E  KD +++ WK P   G +P+ GYF+D  + +   D W   N+  +K  
Sbjct: 943  PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1002

Query: 568  RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAA 604
               V GL EG SY+FRVRA+N+ G+G PS ++ PV A
Sbjct: 1003 YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA 1039



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 1583 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFT--INGVSTAD 1640
            T+ E + + L C++ G P P V+W KN+  +    +        R    T  ING    D
Sbjct: 287  TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346

Query: 1641 SGKYGLVVKNKYGSETSDFTVSV 1663
            + +Y     N  G  ++  +V V
Sbjct: 347  TAQYRASAMNVKGELSAYASVVV 369



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 287  TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
            T+ E + + L C++ G P P V+W KN+  +    +        R    T  ING    D
Sbjct: 1487 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFT--INGVSTAD 1544

Query: 347  TAQYRASAMNVKGELSAYASVVV 369
            + +Y     N  G  ++  +V V
Sbjct: 1545 SGKYGLVVKNKYGSETSDFTVSV 1567


>gi|156104903 myomesin 2 [Homo sapiens]
          Length = 1465

 Score =  862 bits (2228), Expect = 0.0
 Identities = 469/1084 (43%), Positives = 652/1084 (60%), Gaps = 61/1084 (5%)

Query: 625  IIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENW 683
            + V + +P     PG P DL   +A R YV+++WKPP       +M YFV++CE GT NW
Sbjct: 370  LFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNW 429

Query: 684  QRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD------ 737
             + N + PVK  ++ +  L EG+SY FRVR  NSAG+  PS  ++     D LD      
Sbjct: 430  VQCN-DAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQA 488

Query: 738  ---------------------IPKAPGKIIPSRNTDTSVVVSWEE-SKDAKELVGYYIEA 775
                                 +P  P  +  S  +   VV+SWE  +   K+ + Y+IE 
Sbjct: 489  VHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEK 548

Query: 776  SVAGSGKWEPCN-NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAA 834
            SV GSG W+  N    V+  R+    L+ G+SY+FRV + N  GLSE S+ +  I+ +  
Sbjct: 549  SVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQ-- 606

Query: 835  IGGGVSPDVCPALSDEPGGLTASRGR----VHEASPPTFQKDALLGSKPNKPSL------ 884
                   DV   +   PG + ASR      V +   P  ++D LLG   +          
Sbjct: 607  -------DVT-VVPSAPGRVLASRNTKTSVVVQWDRPKHEED-LLGYYVDCCVAGTNLWE 657

Query: 885  PSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSK----SDPLKKKTDRAPPSPPCDI 940
            P + + +G         T  E+     +     G S+    SD +K +     PS P  I
Sbjct: 658  PCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGI 717

Query: 941  TCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISN 1000
            T L     SM LGWK P   GG+ I GYY++ REV       W E N          +  
Sbjct: 718  TLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHK---NWHEVNSSPSKPTILTVDG 774

Query: 1001 LKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWK 1060
            L E  +Y+F++AA+N+AG+G PS  SE FKCE WT+  PGP + L   EVR  SLV+ WK
Sbjct: 775  LTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWK 834

Query: 1061 PPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQ 1120
             PV+SG +PV+GYFVD +E  A E  W  +N+    N YLKV  L++G +YVFRVRA+N 
Sbjct: 835  APVYSGSSPVSGYFVDFREEDAGE--WITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNA 892

Query: 1121 AGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTED 1180
             GVGKPSD + PV+ E RPGTKE+   VD+ G I L F+C +MT  S+F+W K Y    D
Sbjct: 893  NGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISD 952

Query: 1181 SPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHK 1240
              R ++E+ G+ +K+  K+   +DLG YS  V+DTDG++SS+++D EEL+RL+ALS+E K
Sbjct: 953  DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIK 1012

Query: 1241 FPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGI 1300
             PT+P+KSELA EI +KG+VRFW+QAE LS +A   +I N++E+ +   +++  D+ TGI
Sbjct: 1013 NPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGI 1072

Query: 1301 IEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHF 1360
            IEM M++   E+EGTYT Q+ DGKA + S++VL+GD FK + +EAEFQR+E++RKQGPHF
Sbjct: 1073 IEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHF 1132

Query: 1361 VEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSK 1420
             EYL W+VT EC V L CKVAN KKET   W KD+     +   + + GIC LLI + SK
Sbjct: 1133 AEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSK 1192

Query: 1421 KDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSF 1480
            KD G Y+  LKDDRG+D S L++  + + ++++ + +    SA+ LK+  T EGI+L  F
Sbjct: 1193 KDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCF 1252

Query: 1481 VTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGH 1540
            + Y+ +++KVNW H  + I  S+ ++ G + E  WLQI EPT  DKGKY  E+FDGK  H
Sbjct: 1253 MKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNH 1312

Query: 1541 QKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDP 1600
            Q+++DLSGQA+DEA+AEFQ+ K AA AEKNR R++GGLPDVVTI EGK LNLTC V+G+P
Sbjct: 1313 QRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNP 1372

Query: 1601 PPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFT 1660
             PEV W KN++ +   +H ++K E  +    TI GV++ DSGKY + +KNKYG E  D T
Sbjct: 1373 DPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVT 1432

Query: 1661 VSVF 1664
            VSV+
Sbjct: 1433 VSVY 1436



 Score =  667 bits (1720), Expect = 0.0
 Identities = 465/1502 (30%), Positives = 750/1502 (49%), Gaps = 131/1502 (8%)

Query: 138  VPIFSGRQKHVSGITDTEEER--IKEAAAYIAQRNLLASEEGITT-SKQSTASKQTT--- 191
            VP +  R +H        + R  + E A+        +S++ ++  S    AS QT+   
Sbjct: 6    VPFYQKRHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLSQRSSSQRASSQTSLGG 65

Query: 192  ---------ASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRK 242
                      S Q    +++ +  QS  +    A RQ  +S+ A     +E+    +S+ 
Sbjct: 66   TICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHL---EEDVHLARSQA 122

Query: 243  VVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAG 302
               R+K ++ ++++ +E+   +     E+ +  APE +++ RSHTVWE+ +VKL  ++ G
Sbjct: 123  ---RDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQG 179

Query: 303  WPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELS 362
            +P P V WYK+   I   A PGKY IES YG+HTLEIN  DF+DTA Y A A N  G++S
Sbjct: 180  FPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVS 239

Query: 363  AYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETM 422
              A+VVV+R++G+ +  R       +PLS  + PY   + F++ F +KF V+F REGET+
Sbjct: 240  TNAAVVVRRFRGDEEPFRSVGLPIGLPLS-SMIPY---THFDVQFLEKFGVTFRREGETV 295

Query: 423  SLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTI 482
            +L C +++TP++K  QP  +WYR+ V L  SKW +  +   +A+L+FSHL+K+DEGLYT+
Sbjct: 296  TLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTL 355

Query: 483  RVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPIL 542
            R+        +SA++FVRDAD  + GAP AP+D++C +AN+DY+I++WK P     SP++
Sbjct: 356  RIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVM 415

Query: 543  GYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPV 602
            GYF+D+CEVGT++W QCND PVK  ++PVTGL EGRSYIFRVRAVN  GI  PSRVS+ V
Sbjct: 416  GYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAV 475

Query: 603  AALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPG 662
            AALDP +  RL++          I  ++   +  VPGPPT +  +E +R+YVVLSW+PP 
Sbjct: 476  AALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPT 535

Query: 663  QRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGE 722
             RG + +MYF+EK   G+ +WQRVN +  V+SPR+A+FDL EGKSY FRV  +N  G+ E
Sbjct: 536  PRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSE 595

Query: 723  PSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGK 782
            PSE T      D   +P APG+++ SRNT TSVVV W+  K  ++L+GYY++  VAG+  
Sbjct: 596  PSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNL 655

Query: 783  WEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPD 842
            WEPCN+ P+  +RF  HGL TG+ YIFRV+AVNA G+SE SQ+S+ I+V+AA+       
Sbjct: 656  WEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAAL------- 708

Query: 843  VCPALSDEPGGLTASRGRVHEAS-----PPTFQKDALLG-----------------SKPN 880
                +   P G+T      H  +     P       +LG                 S P+
Sbjct: 709  ---TVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPS 765

Query: 881  KPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAP-PSPPCD 939
            KP++ +     G TE S      + ++         +    S+  K +    P P P  D
Sbjct: 766  KPTILTVD---GLTEGS----LYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYD 818

Query: 940  ITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKIS 999
            +T  E    S+V+ WK P   G + ++GY+V++RE      G+W   N    +    K+S
Sbjct: 819  LTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFRE---EDAGEWITVNQTTTANRYLKVS 875

Query: 1000 NLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQW 1059
            +L++   Y F+V A+N  G+G PS  SE    E    A PG    +      + ++ L +
Sbjct: 876  DLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE----ARPG-TKEISAGVDEQGNIYLGF 930

Query: 1060 KPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVR--- 1116
                 +  +  T  +    E  + +++++         +YLK    ++  +Y   V    
Sbjct: 931  DCQEMTDASQFT--WCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTD 988

Query: 1117 AINQAGVGKPSD------LAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFS 1170
             ++ + V  P +      L+  +   T P   E+   + D G +    + + ++P + + 
Sbjct: 989  GVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYR 1048

Query: 1171 W--SKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLI---- 1224
            +  +   VS  +  R++ +      +M      +++ G Y+  + D    + S L+    
Sbjct: 1049 FIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGD 1108

Query: 1225 ------DEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYI 1278
                  +E E +R   L  +           L  ++ E+ +VR   +      N K   +
Sbjct: 1109 AFKTVLEEAEFQRKEFLRKQGPH----FAEYLHWDVTEECEVRLVCKV----ANTKKETV 1160

Query: 1279 FN--EKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGD 1336
            F   + ++    +   +++R  GI E+ + KL  +D G Y   L+D +  + S + + G 
Sbjct: 1161 FKWLKDDVLYETETLPNLER--GICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGK 1218

Query: 1337 VFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDER 1396
            V+  +           + +        L    T E  + L+C +     E  + W   + 
Sbjct: 1219 VYDDMILA--------MSRVCGKSASPLKVLCTPE-GIRLQCFMKYFTDEMKVNWCHKDA 1269

Query: 1397 EISVDE--KHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMME 1454
            +IS  E  +    + +  L I E ++KD G Y   + D +   +  L L  +AF E   E
Sbjct: 1270 KISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAE 1329

Query: 1455 VCKKIALSATDLK----------IQSTAEGIQLYSFVTYYVE-DLKVNWSHNGSAIRYSD 1503
              +  A +  +            + +  EG  L    T +   D +V W  N   I+ S+
Sbjct: 1330 FQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSE 1389

Query: 1504 RVKTGV-TGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLK 1562
                 V   + + + I   T  D GKY + + +   G +  V +S   + E   +    +
Sbjct: 1390 HFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQ 1449

Query: 1563 QA 1564
            QA
Sbjct: 1450 QA 1451



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 18/87 (20%)

Query: 1  MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEA 60
          +++PFYQ+ H+H+D SYRN   R  +  Y  +K+        ST  SS+ S + R     
Sbjct: 4  VTVPFYQKRHRHFDQSYRNIQTRYLLDEYASKKR-------ASTQASSQKSLSQR----- 51

Query: 61 FRRASASSSQQQASQHALSSEVSRKAA 87
                SSSQ+ +SQ +L   + R  A
Sbjct: 52 ------SSSQRASSQTSLGGTICRVCA 72


>gi|155969693 myomesin family, member 3 [Homo sapiens]
          Length = 1437

 Score =  746 bits (1925), Expect = 0.0
 Identities = 427/1094 (39%), Positives = 620/1094 (56%), Gaps = 68/1094 (6%)

Query: 625  IIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQ-RGHEGIMYFVEKCEAGTENW 683
            ++V + E      PG P ++   +  R  ++L+W PP   RG+    Y +E+C+  +  W
Sbjct: 360  VLVRDAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEW 419

Query: 684  QRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK-------- 735
               + E P  + R  +  L EG+SY FRVR  +  G   PS+A+E+ V+GD         
Sbjct: 420  IACH-EAPGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTE 478

Query: 736  -------------------LDIPKAPGKIIPSRNTDTSVVVSWEE-SKDAKELVGYYIEA 775
                               + IP  P  +  S   +  VV++WEE S   +  + Y +E 
Sbjct: 479  IPFDLGNKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRDRAPLTYSLEK 538

Query: 776  SVAGSGKWEPCNN-NPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAA 834
            SV GSG WE  ++ +PV+  RF    L   +SY+FRVRA+N  GLS+ S+ SE I ++  
Sbjct: 539  SVIGSGTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGP 598

Query: 835  IGGGVSPDVCPALSDEPGGLTAS---------------RGRVHEASPPTFQKDALLGSKP 879
                  P    A  D    ++ +                 +V  +   T     + G++ 
Sbjct: 599  PATLPPPAQVQAFRDTQTSVSLTWDPVKDPELLGYYIYSRKVGTSEWQTVNNKPIQGTRF 658

Query: 880  NKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCD 939
              P L +  +   +  V  VSE               +  + ++P++ K   A PS P  
Sbjct: 659  TVPGLRTGKEY--EFCVRSVSEA-----------GVGESSAATEPIRVKQALATPSAPYG 705

Query: 940  ITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKIS 999
               L   ++ MV+GWK P + GG +I GY+++     D     W   N + +     K+S
Sbjct: 706  FALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQH---DSEELDWHAVNQQPIPTRVCKVS 762

Query: 1000 NLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQW 1059
            +L E   Y+F+  A N AG+G  SA S  F+C+EWT+  PGPP+ ++ SEVR  SLVLQW
Sbjct: 763  DLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRATSLVLQW 822

Query: 1060 KPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAIN 1119
            +PP++ G  PVTGY V  +E  +  +QW+ +    I   +L+V  L+ G SYVF+V+A+N
Sbjct: 823  EPPLYMGAGPVTGYHVSFQEEGS--EQWKPVTPGPISGTHLRVSDLQPGKSYVFQVQAMN 880

Query: 1120 QAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTE 1179
             AG+G+PS    PV+ E +PG  E+ V VD++G I L FE  +    SEF WSKDY    
Sbjct: 881  SAGLGQPSMPTDPVLLEDKPGAHEIEVGVDEEGFIYLAFEAPEAPDSSEFQWSKDYKGPL 940

Query: 1180 DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTD-GIASSYLIDEEELKRLLALSHE 1238
            D  R+++E K NK+K+  K+ G++DLG YS  VTD D  I++S+ + EEEL++L  LSHE
Sbjct: 941  DPQRVKIEDKVNKSKVILKEPGLEDLGTYSVIVTDADEDISASHTLTEEELEKLKKLSHE 1000

Query: 1239 HKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNT 1298
             + P + + S   ++ILE+G+VR W++ EKLS  A+++ IFN KEIF  P  K++ DR  
Sbjct: 1001 IRNPVIKLISGWNIDILERGEVRLWLEVEKLSPAAELHLIFNNKEIFSSPNRKINFDREK 1060

Query: 1299 GIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGP 1358
            G++E+ ++ L +ED+G+YT QLQDGKA N  T+ LV D F KL ++A+ +R++W RKQGP
Sbjct: 1061 GLVEVIIQNLSEEDKGSYTAQLQDGKAKNQITLTLVDDDFDKLLRKADAKRRDWKRKQGP 1120

Query: 1359 HFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEF 1418
            +F   L W+VT +C V L CKV N KKET   W+    E+  D ++D + G   L I E 
Sbjct: 1121 YFERPLQWKVTEDCQVQLTCKVTNTKKETRFQWFFQRAEMP-DGQYDPETGTGLLCIEEL 1179

Query: 1419 SKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY 1478
            SKKD GIY  ++ DDRG+D + L L  +A   +  E+ +  ALSAT LKIQ T EGI+++
Sbjct: 1180 SKKDKGIYRAMVSDDRGEDDTILDLTGDALDAIFTELGRIGALSATPLKIQGTEEGIRIF 1239

Query: 1479 SFVTYY-VEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGK 1537
            S V YY VE +K  W H    +   DR++TG T ++IWL I +P  +DKGKY +E+  GK
Sbjct: 1240 SKVKYYNVEYMKTTWFHKDKRLESGDRIRTGTTLDEIWLHILDPKDSDKGKYTLEIAAGK 1299

Query: 1538 TGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVW 1597
               Q + DLSGQA+++A AE QRLK  AI EKNRA+V+ GLPDV TI E K L LTC V 
Sbjct: 1300 EVRQLSTDLSGQAFEDAMAEHQRLKTLAIIEKNRAKVVRGLPDVATIMEDKTLCLTCIVS 1359

Query: 1598 GDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETS 1657
            GDP PE+SWLKN++ +   D   ++   G     TI  V++ DSG+YG+ VKNKYGSET 
Sbjct: 1360 GDPTPEISWLKNDQPVTFLDRYRMEVR-GTEVTITIEKVNSEDSGRYGVFVKNKYGSETG 1418

Query: 1658 DFTVSVFIPEEEAR 1671
              T+SVF   +E +
Sbjct: 1419 QVTISVFKHGDEPK 1432



 Score =  455 bits (1171), Expect = e-127
 Identities = 383/1444 (26%), Positives = 665/1444 (46%), Gaps = 138/1444 (9%)

Query: 175  EEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQ---SVVSKQATSALQ 231
            EE   + +  ++ ++ T        + S A     A+   TAS +       ++ TSA++
Sbjct: 34   EERQHSLRMGSSVRRRTFRSSEEEHEFSAADYALAAALALTASSELSWEAQLRRQTSAVE 93

Query: 232  QEETSEKK---------------SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHA 276
             EE  +K+                   ++R++ +  +LR+  EE      +L E      
Sbjct: 94   LEERGQKRVGFGNDWERTEIAFLQTHRLLRQRRDWKTLRRRTEEKVQEAKELRELCYGRG 153

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHA-NPGKYIIESRYGMH 335
            P F I  RSH VWE   V L C++   P P+VTWYKN   I+      GKY I + YG+ 
Sbjct: 154  PWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLL 213

Query: 336  TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGE---FDETRFHAGASTMPLSF 392
            +LEI  C  ED+A Y     N  G+ S++A V+V+ Y G+   FD   F         +F
Sbjct: 214  SLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVRTYLGKDAGFDSEIFKRS------TF 267

Query: 393  GVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSP 452
            G +         + F       F RE E  SL C  + + ++   +  IQW+R+G  L  
Sbjct: 268  GPS---------VEFTSVLKPVFAREKEPFSLSC--LFSEDVLDAE-SIQWFRDGSLLRS 315

Query: 453  SKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAA 512
            S+  + L++  +A+L  S   KEDEGLY +RV       + S YV VRDA+AE  GAP +
Sbjct: 316  SRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRDAEAENPGAPGS 375

Query: 513  PLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVT 572
            PL+V+CL+ N+D +I++W  P+   G+PI  Y I++C+  +  W  C++ P    R P+ 
Sbjct: 376  PLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHEAPGGTCRCPIQ 435

Query: 573  GLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEP 632
            GL+EG+SY FRVRA++++G   PS+ SE V   D  + AR K+        +I ++ +  
Sbjct: 436  GLVEGQSYRFRVRAISRVGSSVPSKASELVVMGD-HDAARRKTEIPFDLGNKITISTDAF 494

Query: 633  SEGI-VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELP 691
             + + +P PPT++  +E   +YVVL+W+ P  R    + Y +EK   G+  W+ +++E P
Sbjct: 495  EDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRDRAPLTYSLEKSVIGSGTWEAISSESP 554

Query: 692  VKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATE-VTVVGDKLDIPKAPGKIIPSRN 750
            V+SPRFA+ DL + KSY FRVR  N  G+ +PSE +E + + G    +P  P ++   R+
Sbjct: 555  VRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLP-PPAQVQAFRD 613

Query: 751  TDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFR 810
            T TSV ++W+  KD  EL+GYYI +   G+ +W+  NN P++G+RFT  GL TG+ Y F 
Sbjct: 614  TQTSVSLTWDPVKD-PELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFC 672

Query: 811  VRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLT--------ASRGRVH 862
            VR+V+ AG+ E S  +E I VK A+    +P     L+     +            G++ 
Sbjct: 673  VRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVIGWKPPKRRGGGKIL 732

Query: 863  EASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAA-----PQ 917
                     + L     N+  +P        T V KVS+  +        +AA      +
Sbjct: 733  GYFLDQHDSEELDWHAVNQQPIP--------TRVCKVSDLHEGHFYEFRARAANWAGVGE 784

Query: 918  GKSKSDPLKKKTDRAP-PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVI 976
              + S   + K    P P PP D+   E    S+VL W+ P  +G   +TGY+V+++E  
Sbjct: 785  LSAPSSLFECKEWTMPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQE-- 842

Query: 977  DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
            +G   +W+      +S    ++S+L+    Y FQV AMN AGLG PS  ++    E+   
Sbjct: 843  EG-SEQWKPVTPGPISGTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLED--- 898

Query: 1037 AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI- 1095
              PG  H ++     +  + L ++ P      P +  F   K+ K   D  R   E  + 
Sbjct: 899  -KPG-AHEIEVGVDEEGFIYLAFEAP----EAPDSSEFQWSKDYKGPLDPQRVKIEDKVN 952

Query: 1096 -KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEV---------- 1144
               V LK  GL++  +Y   V   ++  +     L    + + +  + E+          
Sbjct: 953  KSKVILKEPGLEDLGTYSVIVTDADE-DISASHTLTEEELEKLKKLSHEIRNPVIKLISG 1011

Query: 1145 -VVNVDDDGVISLNFECDKMTPKSEFS--WSKDYVSTEDSPRLEVESKGNKTKMTFKDLG 1201
              +++ + G + L  E +K++P +E    ++   + +  + ++  + +    ++  ++L 
Sbjct: 1012 WNIDILERGEVRLWLEVEKLSPAAELHLIFNNKEIFSSPNRKINFDREKGLVEVIIQNLS 1071

Query: 1202 MDDLGIYSCDVTD--TDGIASSYLIDEE---ELKRLLALSHEHKFPTVP-VKSELAVEIL 1255
             +D G Y+  + D       +  L+D++    L++  A   + K    P  +  L  ++ 
Sbjct: 1072 EEDKGSYTAQLQDGKAKNQITLTLVDDDFDKLLRKADAKRRDWKRKQGPYFERPLQWKVT 1131

Query: 1256 EKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGT 1315
            E  QV+   +        +  + F   E+ +G       D  TG   + +E+L  +D+G 
Sbjct: 1132 EDCQVQLTCKVTNTKKETRFQWFFQRAEMPDG-----QYDPETGTGLLCIEELSKKDKGI 1186

Query: 1316 YTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGE-CNV 1374
            Y   + D +  + + + L GD    +  E        + + G      L  + T E   +
Sbjct: 1187 YRAMVSDDRGEDDTILDLTGDALDAIFTE--------LGRIGALSATPLKIQGTEEGIRI 1238

Query: 1375 LLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDR 1434
              K K  N+ +     W+  ++ +   ++      +  + +     KD+   +  L+   
Sbjct: 1239 FSKVKYYNV-EYMKTTWFHKDKRLESGDRIRTGTTLDEIWLHILDPKDSDKGKYTLEIAA 1297

Query: 1435 GKDKSRLK--LVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDL---- 1488
            GK+  +L   L  +AF++ M E  +   L+  +   ++ A+ ++    V   +ED     
Sbjct: 1298 GKEVRQLSTDLSGQAFEDAMAEHQRLKTLAIIE---KNRAKVVRGLPDVATIMEDKTLCL 1354

Query: 1489 ----------KVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY---VMELFD 1535
                      +++W  N   + + DR +  V G ++ + I +    D G+Y   V   + 
Sbjct: 1355 TCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFVKNKYG 1414

Query: 1536 GKTG 1539
             +TG
Sbjct: 1415 SETG 1418



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 283  PRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGC 342
            P   T+ E + + L C ++G P P ++W KN  P+       +Y +E R    T+ I   
Sbjct: 1341 PDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTF---LDRYRMEVRGTEVTITIEKV 1397

Query: 343  DFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETR 380
            + ED+ +Y     N  G  +   ++ V ++  E  E +
Sbjct: 1398 NSEDSGRYGVFVKNKYGSETGQVTISVFKHGDEPKELK 1435



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 13/82 (15%)

Query: 1584 IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGR--------TAYFTING 1635
            + E   + LTC V   PPP+V+W KN+  +         F AG+             I  
Sbjct: 165  VWEHTTVLLTCTVQASPPPQVTWYKNDTRIDP-----RLFRAGKYRITNNYGLLSLEIRR 219

Query: 1636 VSTADSGKYGLVVKNKYGSETS 1657
             +  DS  Y + VKN +G  +S
Sbjct: 220  CAIEDSATYTVRVKNAHGQASS 241


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score =  257 bits (656), Expect = 8e-68
 Identities = 233/902 (25%), Positives = 381/902 (42%), Gaps = 102/902 (11%)

Query: 405   IHFDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGE 463
             +  D KF DV   + GE + +   +   P      P I W ++G+ +      + + +  
Sbjct: 25789 VMMDVKFRDVIVVKAGEVLKINADIAGRP-----LPVISWAKDGIEIEERARTEIISTDN 25843

Query: 464   RATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANK 523
                LT     + D G Y + ++        +    V D      G PA PL++  L A K
Sbjct: 25844 HTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKP----GPPAGPLEINGLTAEK 25899

Query: 524   DYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFR 583
                 +SW +P  DGG+ I  Y ++K E    +W+ C +  ++     VT L++G  YIFR
Sbjct: 25900 --CSLSWGRPQEDGGADIDYYIVEKRETSHLAWTIC-EGELQMTSCKVTKLLKGNEYIFR 25956

Query: 584   VRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTD 643
             V  VNK G+G P   S  + ALDP                             VP PPT 
Sbjct: 25957 VTGVNKYGVGEPLE-SVAIKALDPFT---------------------------VPSPPTS 25988

Query: 644   LSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDL 702
             L +T  T+  + L W +P    G E   Y +E+ E  +  W RVN + PV   R     L
Sbjct: 25989 LEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKK-PVYDLRVKSTGL 26047

Query: 703   AEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES 762
              EG  Y +RV   N+AG+  PSE + +    D + +P  P K     +  T++ ++W + 
Sbjct: 26048 REGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKP 26107

Query: 763   --KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLS 820
                    + GY +E   +    W+    + ++G+ +T  GL TG  Y+FRV++VN  G S
Sbjct: 26108 LFDGGAPITGYTVEYKKSDDTDWKTSIQS-LRGTEYTISGLTTGAEYVFRVKSVNKVGAS 26166

Query: 821   EYSQDSE---AIEVKAAIGGGVSPDVCPALSDEPGG----LTASRGR----VHEASPPT- 868
             + S  S+   A E +      +  ++   L  + G         RGR    V  + P T 
Sbjct: 26167 DPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTD 26226

Query: 869   FQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKK 928
              +  A + +  ++ SL  + +N  + +  K + T+Q  L+           +    + K 
Sbjct: 26227 LRTRAYVDTTDSRTSL--TIENANRNDSGKYTLTIQNVLS----------AASLTLVVKV 26274

Query: 929   TDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
              D   P PP +IT  +  ++S VL W  P+  GGA +  Y++  RE       K   +  
Sbjct: 26275 LD--TPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKRE----ASKKAWVSVT 26328

Query: 989   KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCS 1048
                +  +YK++NL+E  +Y F+V+  N  G+G P+   E  K  E     P PP  L  +
Sbjct: 26329 NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITE----KPSPPEKLGVT 26384

Query: 1049  EVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEG 1108
              + KDS+ L W  P H G + +  Y V+  E   K   W  +  A  K+ +  V GL+E 
Sbjct: 26385 SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK--NW--VKCAVAKSTHHVVSGLREN 26440

Query: 1109  VSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISL----NFECD--- 1161
               Y FRV A NQAG+  P +L  PV+ + +    E+ +       + +    N + D   
Sbjct: 26441 SEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPI 26500

Query: 1162  KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
                P  + + S+D V  + + R   E       +  K+    D G Y     ++ G   +
Sbjct: 26501 SGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKA 26560

Query: 1222  YLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNE 1281
             ++        ++ L      P  P    +  +I E+     W   +   G+   NYI  +
Sbjct: 26561 FI-------NIVVLDR----PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLK 26609

Query: 1282  KE 1283
             +E
Sbjct: 26610 RE 26611



 Score =  248 bits (632), Expect = 5e-65
 Identities = 214/828 (25%), Positives = 356/828 (42%), Gaps = 107/828 (12%)

Query: 429   VITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGE 488
             ++ P   + + E +W++   PLS +K + T  + E+ +       K D+G Y I ++   
Sbjct: 13019 MVVPYDAYPKAEAEWFKENEPLS-TKTIDT--TAEQTSFRILEAKKGDKGRYKIVLQ--N 13073

Query: 489   YYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDK 548
              + +   ++ ++  D      P    +++  E     + ++W++P  DGGS I+GY +++
Sbjct: 13074 KHGKAEGFINLKVIDV-----PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVER 13128

Query: 549   CEVGTDSWSQCNDTPVKFARFPVTGLIEGR-SYIFRVRAVNKMGIGFPSRVSEPVAALDP 607
              ++   +W    D   +   F VTGL +G   Y+FRV A N++G G P     PV     
Sbjct: 13129 RDIKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPV----- 13182

Query: 608   AEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHE 667
                                   E  S+  VPGPP ++++T+  R  V L+W+PP   G  
Sbjct: 13183 ----------------------EARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGA 13220

Query: 668   GIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEA 726
              I  Y +E  +  +  W    T +  +     + D+ EG+ Y FRVR  N  GVG+PS A
Sbjct: 13221 EITNYVIELRDKTSIRWDTAMT-VRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAA 13279

Query: 727   TEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-KD-AKELVGYYIEASVAGSGKWE 784
             T    V D ++ P  P  +  S  T +SV + WE   KD    ++GY IE    G   W 
Sbjct: 13280 TPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWI 13339

Query: 785   PCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVC 844
              CN   V    +   GL  G  Y++RV A N AG+S+ S+                    
Sbjct: 13340 RCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEIL------------------ 13381

Query: 845   PALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVS-----KV 899
                    G LTA    V      +  KD L    PN  ++   S    +   +     KV
Sbjct: 13382 -------GPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 13434

Query: 900   SET----------VQEELTPPPQKAAPQG------KSKSDPLKKKTD---RAPPSPPCDI 940
              ET             EL   P + + +G      +++   +  + D    A PS P ++
Sbjct: 13435 LETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKEL 13494

Query: 941   TCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISN 1000
                +  +DS+ L W+ PD  GG+ +TGY V  REV       W +  +  V++  + + +
Sbjct: 13495 KFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKT---WTKV-MDFVTDLEFTVPD 13550

Query: 1001  LKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWK 1060
             L +   Y F+V A N  G G P+ V E          VP PP ++K  +   +S+ L W 
Sbjct: 13551 LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMST-PATVPDPPENVKWRDRTANSIFLTWD 13609

Query: 1061  PPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQ 1120
             PP + G + + GY V+        D+W    E  +    ++V GL+EG  Y +RV+A+N+
Sbjct: 13610 PPKNDGGSRIKGYIVE--RCPRGSDKWVACGE-PVAETKMEVTGLEEGKWYAYRVKALNR 13666

Query: 1121  AGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISL----NFECDKMT---PKSEFSWSK 1173
              G  KPS     + A       E+ ++V     +++      E        P+ + +W+K
Sbjct: 13667 QGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTK 13726

Query: 1174  DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
               +  +   R+ +E+   K+ +T  D    D G Y  +  +  G A++
Sbjct: 13727 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATA 13774



 Score =  247 bits (631), Expect = 6e-65
 Identities = 233/877 (26%), Positives = 353/877 (40%), Gaps = 116/877 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P + W ++G  L P++ ++        TL    +N++D G YTI        +  +  + 
Sbjct: 19325 PTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLK 19384

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V D        P  P  VK  +   D  ++SW+ P  DGGS I  Y +DK E    +W+Q
Sbjct: 19385 VLDK-------PGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQ 19437

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              + T V      V  LIEG  Y FR+ A NK G+G P   +EP  A +P +         
Sbjct: 19438 VSAT-VPITSCSVEKLIEGHEYQFRICAENKYGVGDPV-FTEPAIAKNPYDP-------- 19487

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                                PG      ++  T+ ++ +SWKPP   G   I  Y +EK E
Sbjct: 19488 -------------------PGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRE 19528

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
                 NW +VN + P+         L EG  Y FRV   N AG G+PS+A++     D   
Sbjct: 19529 TQAVNWTKVNRK-PIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQY 19587

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCN-NNPVKGS 794
              P  P        T +SV +SW +        ++GY +E   A S  W  CN    ++ +
Sbjct: 19588 PPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 19647

Query: 795   RFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAI---GGGVSPDVCPALSDEP 851
             RF   GL+    Y FRV AVN  G S+ S   +    K  +    G +  D+   L    
Sbjct: 19648 RFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRA 19707

Query: 852   GGLTASRGRVHEASPPTFQKDALLGSKPN-----KPSLPSSS---------QNLGQTEVS 897
             G        V    PP      +  SKPN     +  L   S         +N+ + +  
Sbjct: 19708 GVTMRLYVPVKGRPPP-----KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 19762

Query: 898   KVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQP 957
             K   T++             GK +   + K  D   P PP ++T  E  +DS  + W+ P
Sbjct: 19763 KYILTLENSC----------GKKEYTIVVKVLD--TPGPPVNVTVKEISKDSAYVTWEPP 19810

Query: 958   DKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMA 1017
                GG+ I  Y V  R   D     W     +  S+ +++++NL+E   Y F+V A N  
Sbjct: 19811 IIDGGSPIINYVVQKR---DAERKSWSTVTTEC-SKTSFRVANLEEGKSYFFRVFAENEY 19866

Query: 1018  GLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDL 1077
             G+G P    +  K  +     PGP   LK   V K S  + WK P   G + + GY VD 
Sbjct: 19867 GIGDPGETRDAVKASQ----TPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 19922

Query: 1078  KEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET 1137
                  +E++W+ + ++   ++    + L EG  Y FRV A N+ G G PS++   VVA  
Sbjct: 19923 ---LTEENKWQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVAR- 19974

Query: 1138  RPGTKEVVVNVDDDGVISL--------NFECD---KMTPKSEFSWSKDYVSTEDSPRLEV 1186
                   V  ++D  G+  L        NF      K  P    SW K         R+ V
Sbjct: 19975 ---DDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 20031

Query: 1187  ESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPV 1246
             ES    T +   D    D G Y+  + +  G     +         + +  +   PT P+
Sbjct: 20032 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTI--------SIKVVGKPGIPTGPI 20083

Query: 1247  KSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
             K +   E+  +     W   +   G+   NYI  +++
Sbjct: 20084 KFD---EVTAEAMTLKWAPPKDDGGSEITNYILEKRD 20117



 Score =  247 bits (630), Expect = 8e-65
 Identities = 216/807 (26%), Positives = 347/807 (42%), Gaps = 78/807 (9%)

Query: 438   QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
             +P+I W +  + L   K +      +++T+T     + D G Y I         + +A V
Sbjct: 13719 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAV--NVCGRATAVV 13776

Query: 498   FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
              V   D      P  P      +   +  +++W  P  DGGS I  Y +++    ++ W 
Sbjct: 13777 EVNVLDK-----PGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWH 13831

Query: 558   QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAA---LDPAEKARLK 614
             + + T VK   F  T LI  + YIFRV A N  G+G P + S P+ A    DP       
Sbjct: 13832 KLSST-VKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQAS-PITAKYQFDP------- 13882

Query: 615   SRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFV 673
                                    PGPPT L  ++ T+  V L+W  P   G   I  Y+V
Sbjct: 13883 -----------------------PGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWV 13919

Query: 674   EKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVG 733
             E+ +  T+ W R N ++PVK   + +  L   K Y FRV   N AG G+PS++TE  ++ 
Sbjct: 13920 ERLDPDTDKWVRCN-KMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIK 13978

Query: 734   DKLDIPKAPGKIIPSRNTDTSVVVSW--EESKDAKELVGYYIEASVAGSGKWEPCNNNPV 791
             D +D P  PGK        TSV ++W   E     ++  Y IE    G+ +W       V
Sbjct: 13979 DPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEG-V 14037

Query: 792   KGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEP 851
               ++    GL+ GQ Y FRVRAVN AG SE S+ S+ +  +  +     P     ++   
Sbjct: 14038 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN--- 14094

Query: 852   GGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETV---QEELT 908
               +T +   +    P       +      K  +         T V     TV    E   
Sbjct: 14095 --ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSL 14152

Query: 909   PPPQKAAPQGKSKS------DPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGG 962
                + AA     +S      D +  K     P PP  +  ++  +  + L W+ P   GG
Sbjct: 14153 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGG 14212

Query: 963   AEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
               I  Y +  +E +     +W +A   A  +  ++++++ E    QFQV A N AG+G P
Sbjct: 14213 RPIQRYVIEKKERLG---TRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHP 14269

Query: 1023  SAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKA 1082
             S  +E    E+ T + P PP  L  ++  +  + + WKPP  +G +P+ GY V++     
Sbjct: 14270 SEPTEILSIEDPT-SPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEM--CPV 14326

Query: 1083  KEDQWRGLNEAAIKNVYLKV-RGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA---ETR 1138
               ++W  +N   IK++  KV  G+     YV RVRA+N  GV +PS+++  VVA   + +
Sbjct: 14327 GTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCK 14386

Query: 1139  P----GTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTK 1194
             P     T +++V   +   I + F   +  P    SW KD    + S RL +++      
Sbjct: 14387 PTIDLETHDIIVIEGEKLSIPVPF---RAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 14443

Query: 1195  MTFKDLGMDDLGIYSCDVTDTDGIASS 1221
             +        D GIY+  + +  G A++
Sbjct: 14444 LEVPKSVRADAGIYTITLENKLGSATA 14470



 Score =  244 bits (623), Expect = 5e-64
 Identities = 210/715 (29%), Positives = 320/715 (44%), Gaps = 77/715 (10%)

Query: 432   PEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHL---NKEDEGLYTIRVR--M 486
             P I   +P I W ++G PL  +  V      E AT T  H+   NK+D G YT+      
Sbjct: 24334 PVIGRPRPNISWVKDGEPLKQTTRVNV---EETATSTVLHIKEGNKDDFGKYTVTATNSA 24390

Query: 487   GEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFI 546
             G   E  S  V       E  G P  P  V+  E + D+++ISW+ PA  GG  I  Y +
Sbjct: 24391 GTATENLSVIVL------EKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYIV 24442

Query: 547   DKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALD 606
             +K +  T +W   + T  +     +T L  G  Y FR+ A N+ G               
Sbjct: 24443 EKRDTTTTTWHMVSATVAR-TTIKITKLKTGTEYQFRIFAENRYG--------------- 24486

Query: 607   PAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGH 666
                        SAP   + ++ +    E   PGPP    VT  ++  +++ W  P   G 
Sbjct: 24487 ----------KSAPLDSKAVIVQYPFKE---PGPPGTPFVTSISKDQMLVQWHEPVNDGG 24533

Query: 667   EGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSE 725
               I+ Y +E+ E  +  W ++N + P++  +F    L EG  Y F+V   N  G+G+PS+
Sbjct: 24534 TKIIGYHLEQKEKNSILWVKLN-KTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 24592

Query: 726   ATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKW 783
              +E  V  D  D P  P  I+ +RN   +V + W++       ++ GY +E      G+W
Sbjct: 24593 VSECFVARDPCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW 24649

Query: 784   EPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAI---GGGV 839
                +   V  + FT  GLV  Q Y FRV A NAAG  SE S  S AI  +  I      +
Sbjct: 24650 MKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASL 24709

Query: 840   SP---DVCPALSDEPGGLTAS-RGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTE 895
              P   DV    + E   L A  RG+        + KD   G +  + +     ++  Q  
Sbjct: 24710 DPKYKDVIVVHAGETFVLEADIRGK--PIPDVVWSKD---GKELEETAARMEIKSTIQKT 24764

Query: 896   VSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKT-DR-APPSPPCDITCLESFRDSMVLG 953
                V + ++ +      K +  G +KS P+  K  DR  PP  P  +T + +  +   L 
Sbjct: 24765 TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTA--EKCYLA 24822

Query: 954   WKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAA 1013
             W  P + GGA I+ Y +  RE        W + + + V    YK++ L     Y F+V A
Sbjct: 24823 WNPPLQDGGANISHYIIEKRET---SRLSWTQVSTE-VQALNYKVTKLLPGNEYIFRVMA 24878

Query: 1014  MNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGY 1073
             +N  G+G P        C  +    PGPP + + S + KDS+V+ W  PV  G T + GY
Sbjct: 24879 VNKYGIGEPLESGPVTACNPY--KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY 24936

Query: 1074  FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              ++ ++ +    +W   N+  + ++ L+V GL EG SY FRV A N AGVG+PS+
Sbjct: 24937 ILEKRDKEGV--RWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSE 24989



 Score =  240 bits (612), Expect = 1e-62
 Identities = 232/891 (26%), Positives = 374/891 (41%), Gaps = 101/891 (11%)

Query: 417   REGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             R G  + L   V   PE     P+I W +    L   + V   ++G+RAT      ++ D
Sbjct: 29060 RAGSDLVLDAAVGGKPE-----PKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSD 29114

Query: 477   EGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVD 536
              G YT+ V+     +  S  V V D+       P   L V  +   K    ++W  P  D
Sbjct: 29115 SGKYTLTVKNASGTKAVSVMVKVLDSPG-----PCGKLTVSRVTQEK--CTLAWSLPQED 29167

Query: 537   GGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPS 596
             GG+ I  Y +++ E    +W          + + VT LI+   YIFRVRAVNK G G P 
Sbjct: 29168 GGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYGPGVPV 29226

Query: 597   RVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVL 656
               SEP+ A +                              +P PP         + ++++
Sbjct: 29227 E-SEPIVARNSFT---------------------------IPSPPGIPEEVGTGKEHIII 29258

Query: 657   SW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCS 715
              W KP    G+E   Y V+K E  +  W RVN +  V   R  +  L EG  Y FRV   
Sbjct: 29259 QWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAV 29318

Query: 716   NSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYI 773
             N+AG  EPSEA+      +    P  P        T  S+ ++W +       ++VGY +
Sbjct: 29319 NAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVL 29378

Query: 774   EASVAGSGKWEPCNNN-PVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVK 832
             E     + +W   + N  ++ + FT   L  GQ Y FRV AVN  G+SEYS+    IE  
Sbjct: 29379 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 29438

Query: 833   AAI---GGGVSPDVCPALSDEPGGLTASRGRVHEASPP--TFQKDAL-LGSKPNKPSLPS 886
               I      ++ D+   ++   G        V    PP  T+ K  + L S+    ++  
Sbjct: 29439 ERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASR----AIID 29494

Query: 887   SSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESF 946
             ++++     V KV+     + T   +  +  GK  +  L K  D   P P   +   E  
Sbjct: 29495 TTESYSLLIVDKVNRYDAGKYTIEAENQS--GKKSATVLVKVYDTPGPCP--SVKVKEVS 29550

Query: 947   RDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMV 1006
             RDS+ + W+ P   GGA +  Y V  RE        ++    K  S+  Y+IS L E  +
Sbjct: 29551 RDSVTITWEIPTIDGGAPVNNYIVEKRE---AAMRAFKTVTTKC-SKTLYRISGLVEGTM 29606

Query: 1007  YQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSG 1066
             Y F+V   N+ G+G P   S+     E    VP  P  L+  +V K ++ L W+ P++ G
Sbjct: 29607 YYFRVLPENIYGIGEPCETSDAVLVSE----VPLVPAKLEVVDVTKSTVTLAWEKPLYDG 29662

Query: 1067  RTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLK--VRGLKEGVSYVFRVRAINQAGVG 1124
              + +TGY   L+  KA  ++W  +    +K   L+  V  L EG  Y+FR+RA N+ GV 
Sbjct: 29663 GSRLTGYV--LEACKAGTERW--MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVS 29718

Query: 1125  KPSDLAGPVVAE-----------TRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSK 1173
             +P +    V  +           T P   +  ++V     + L        P +  SW  
Sbjct: 29719 EPRETVTAVTVQDLRVLPTIDLSTMP---QKTIHVPAGRPVELVIPIAGRPPPAA-SWFF 29774

Query: 1174  DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLL 1233
                   +S R+ VE+     K+T ++  + D G Y+ ++ +  G  S       E  +++
Sbjct: 29775 AGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTS-------ETIKVI 29827

Query: 1234  ALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVN-YIFNEKE 1283
              L      PT P+K    ++ ++   +    +  +L G A ++ Y+  +++
Sbjct: 29828 ILDKPGP-PTGPIK----IDEIDATSITISWEPPELDGGAPLSGYVVEQRD 29873



 Score =  239 bits (609), Expect = 2e-62
 Identities = 243/973 (24%), Positives = 389/973 (39%), Gaps = 133/973 (13%)

Query: 339   INGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYG 398
             + G    DT +YR SA+N+ G+            K E      H                
Sbjct: 16778 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLH---------------- 16821

Query: 399   YASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQT 458
                   + F DK  +   R GE  +L  R    P+     P++ W+++   +        
Sbjct: 16822 ------LDFRDKLTI---RVGEAFALTGRYSGKPK-----PKVSWFKDEADVLEDDRTHI 16867

Query: 459   LWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKC 518
               +     L      + D G Y + V       +    V V D      G P  P+    
Sbjct: 16868 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRP----GPPVGPVSFD- 16922

Query: 519   LEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGR 578
              E  KDY++ISWK P  DGGS I  Y I+K EVG D W        K     V+ L+EG+
Sbjct: 16923 -EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAK-TTCKVSKLLEGK 16980

Query: 579   SYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVP 638
              YIFR+ A N  GI      S+P+ +     K R +                      VP
Sbjct: 16981 DYIFRIHAENLYGI------SDPLVSDSMKAKDRFR----------------------VP 17012

Query: 639   GPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFA 698
               P    VTE T+   +++W  P   G     Y +EK E  ++ W RV  +      +F 
Sbjct: 17013 DAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFR 17072

Query: 699   LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVS 758
             + DL EG  Y FRV   N  G+G+PS  ++     D +  P  P        T  SV ++
Sbjct: 17073 VPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLT 17132

Query: 759   WEESK--DAKELVGYYIEASVAGSGKWEPCNNNP--VKGSRFTCHGLVTGQSYIFRVRAV 814
             W+  +     +++GY +E    G  +W   N+ P     +++   GL  GQ+Y FRV AV
Sbjct: 17133 WQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAV 17192

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGR-VHEASPPTFQKDA 873
             NAAG S+ +   E + VK  +     P++          L A+  R  H     T +  A
Sbjct: 17193 NAAGESDPAHVPEPVLVKDRL---EPPELI---------LDANMAREQHIKVGDTLRLSA 17240

Query: 874   LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSD---------- 923
             ++   P  P +    ++      +++      ++TP   K   +  +  D          
Sbjct: 17241 IIKGVP-FPKVTWKKEDRDAPTKARI------DVTPVGSKLEIRNAAHEDGGIYSLTVEN 17293

Query: 924   PLKKKTDRA------PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVID 977
             P   KT          P PP D+   E  +DS  L WK+P   GG+ IT Y V  R+V  
Sbjct: 17294 PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDV-- 17351

Query: 978   GVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIA 1037
                 +W   +  +  ++++   +L E   Y F+VAA N  G G      +  K  +  + 
Sbjct: 17352 -ASAQWSPLSATS-KKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD-PLH 17408

Query: 1038  VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
              PGPP  L   +V K  + L W  P   G +P+TGY V+ +E   ++  W  +    + N
Sbjct: 17409 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQD--W--IKFKTVTN 17464

Query: 1098  VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR--PGTKEVVVNVDDDGVI- 1154
             +   V GL++G +Y FRV+A N  G+G P D   P+  + +  P + E+ V + +  V+ 
Sbjct: 17465 LECVVTGLQQGKTYRFRVKAENIVGLGLP-DTTIPIECQEKLVPPSVELDVKLIEGLVVK 17523

Query: 1155  ---SLNFEC-DKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSC 1210
                ++ F    +  P     W+ D    +      VE+    + +T K+    D G Y  
Sbjct: 17524 AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 17583

Query: 1211  DVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLS 1270
              V++  G         + +   L +      PT P+     +++  +     W   +   
Sbjct: 17584 TVSNAAG--------SKTVAVHLTVLDVPGPPTGPIN---ILDVTPEHMTISWQPPKDDG 17632

Query: 1271  GNAKVNYIFNEKE 1283
             G+  +NYI  +++
Sbjct: 17633 GSPVINYIVEKQD 17645



 Score =  238 bits (606), Expect = 5e-62
 Identities = 256/1027 (24%), Positives = 414/1027 (40%), Gaps = 150/1027 (14%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             +N+K+   + G P+P VTW K      +     +   E+      L IN C   D+  Y 
Sbjct: 21081 DNIKVEIPVLGRPKPTVTWKKGD---QILKQTQRVNFETTATSTILNINECVRSDSGPYP 21137

Query: 352   ASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKF 411
              +A N+ GE+    ++ V    G            T P+ F      +            
Sbjct: 21138 LTARNIVGEVGDVITIQVHDIPGP----------PTGPIKFDEVSSDF------------ 21175

Query: 412   DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH 471
              V+F  +      G        I ++  E++          + WV+   +  R T   + 
Sbjct: 21176 -VTFSWDPPENDGGV------PISNYVVEMR------QTDSTTWVELATTVIRTTYKATR 21222

Query: 472   LNKEDEGLYTIRVRMGEYY---EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIII 528
             L    E  Y  RV+    Y      ++   V +   ++ G P  P   +     KD + I
Sbjct: 21223 LTTGLE--YQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTP---QVTAVTKDSMTI 21277

Query: 529   SWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVN 588
             SW +P  DGGSPILGY +++ E     W   +   V    F  +GL +G +Y FRV A N
Sbjct: 21278 SWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAEN 21337

Query: 589   KMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTE 648
               G   PS+ SEP+ ALDP +                            PG P  L++T 
Sbjct: 21338 MAGKSKPSKPSEPMLALDPIDP---------------------------PGKPVPLNITR 21370

Query: 649   ATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKS 707
              T   V L W KP    G +   Y VEK +     W + N    +++  F +  L E  +
Sbjct: 21371 HT---VTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILEN-EFTVSGLTEDAA 21426

Query: 708   YCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAK 766
             Y FRV   N+AG +  PSE ++     D ++ PK              V V ++++   K
Sbjct: 21427 YEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKI------------KVDVKFKDTVILK 21474

Query: 767   ELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDS 826
                 + +EA V  SG+  P       G        +  +   F    VN        +DS
Sbjct: 21475 AGEAFRLEADV--SGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNK---DSTRRDS 21529

Query: 827   EAIEVKAAIGGGVSPDVC-------PALSDEPGGLT--ASRGRVHEASPPTFQKDALLG- 876
              A  + A   GG +  +        P   + P  +T   S   V    PP     A +  
Sbjct: 21530 GAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDH 21589

Query: 877   --------SKPNKPSLPSSSQ--NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLK 926
                     S+    ++ S  Q   L  T++ K +E +   +     K       +S+P+ 
Sbjct: 21590 YIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV--NKYGVGEPLESEPVL 21647

Query: 927   KKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREA 986
                   PP PP +       +DSMV+ W  PD  GG+EI  Y V  R   D    +W + 
Sbjct: 21648 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERR---DKAGQRWIKC 21704

Query: 987   NVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK-CEEWTIAVPGPPHSL 1045
             N K +++  YK+S L E   Y+F++ A N AG+ APS  S  +K C+  T+  PGPP + 
Sbjct: 21705 NKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD--TVFKPGPPGNP 21762

Query: 1046  KCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRG 1104
             +  +  + S+ + W  P++ G + +TGY V++  A  +ED+W+ +   A +K     + G
Sbjct: 21763 RVLDTSRSSISIAWNKPIYDGGSEITGYMVEI--ALPEEDEWQIVTPPAGLKATSYTITG 21820

Query: 1105  LKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECD--- 1161
             L E   Y  R+ A+N  G+G+P+ + G   AE R    E+ ++ D   V+++   C    
Sbjct: 21821 LTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRL 21880

Query: 1162  ----KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
                 K  P  E  W++D+  + D  +  +ES  + T +   ++   D G Y   V ++ G
Sbjct: 21881 FVPIKGRPAPEVKWARDHGESLD--KASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG 21938

Query: 1218  IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV-N 1276
               S+++             +     T     +L V+ + K  V        L G +K+ N
Sbjct: 21939 SKSAFV-------------NVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 21985

Query: 1277  YIFNEKE 1283
             YI  ++E
Sbjct: 21986 YIVEKRE 21992



 Score =  236 bits (602), Expect = 1e-61
 Identities = 213/769 (27%), Positives = 319/769 (41%), Gaps = 97/769 (12%)

Query: 398   GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPE-----------IQWYRN 446
             G   +F +   +   VS  RE E +      ++ P+I    PE           I+ +  
Sbjct: 18866 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI--LMPEQITIKAGKKLRIEAHVY 18923

Query: 447   GVPLSPSKWVQTLWSGERATLTFSHL----------------NKEDEGLYTIRVRMGEYY 490
             G P    KW +    GE   +T SHL                 ++D G Y++        
Sbjct: 18924 GKPHPTCKWKK----GEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGT 18979

Query: 491   EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCE 550
             +     V V DA     G P  P D+  ++A  D   +SW  P  DGGS I  Y ++KC+
Sbjct: 18980 DTQKIKVVVMDAP----GPPQPPFDISDIDA--DACSLSWHIPLEDGGSNITNYIVEKCD 19033

Query: 551   VGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEK 610
             V    W     +  K +   V  LI G+ YIFRVRA N+ GI  P    + VA       
Sbjct: 19034 VSRGDWVTALASVTKTS-CRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG-- 19090

Query: 611   ARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM 670
                                       VP  P +  VT+  +  + ++W  P   G   I+
Sbjct: 19091 --------------------------VPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPII 19124

Query: 671   -YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEV 729
              Y +E+ E  +  W + N  L V+S  +    L EG  Y FR+   N AG   PS+ TE 
Sbjct: 19125 GYLIERKERNSLLWVKANDTL-VRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEY 19183

Query: 730   TVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNN 789
                   +D P  P  I  +++T  S++ +  +     +++GY++EA      KW  CN  
Sbjct: 19184 VTARMPVDPPGKPEVIDVTKST-VSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTA 19242

Query: 790   P--VKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSP--DVCP 845
             P  +    +T  GL     Y FR  A  A  +S  S+ S+ + + A     V P  D+  
Sbjct: 19243 PHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAE---NVPPRIDLSV 19299

Query: 846   ALSD----EPGGLTASRGRVHEASPPT--FQKDALLGSKPNKPSLPSSSQNLGQTEVSKV 899
             A+      + G        V     PT  ++KD  L  KP +    +  +NL   E+  V
Sbjct: 19300 AMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL-LKPAEGIKMAMQRNLCTLELFSV 19358

Query: 900   SETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDK 959
             +     + T   + ++    SKS  +K K     P PP  +   + + D  +L W+ P +
Sbjct: 19359 NRKDSGDYTITAENSSG---SKSATIKLKV-LDKPGPPASVKINKMYSDRAMLSWEPPLE 19414

Query: 960   IGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GG+EIT Y V+ RE        W + +   V   +  +  L E   YQF++ A N  G+
Sbjct: 19415 DGGSEITNYIVDKRETSRP---NWAQVSA-TVPITSCSVEKLIEGHEYQFRICAENKYGV 19470

Query: 1020  GAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
             G P           +    PG       S + KD + + WKPP   G +P+TGY ++ +E
Sbjct: 19471 GDPVFTEPAIAKNPYD--PPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRE 19528

Query: 1080  AKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              +A    W  +N   I    LK  GL+EG  Y FRV AIN+AG GKPSD
Sbjct: 19529 TQAVN--WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 19575



 Score =  235 bits (600), Expect = 2e-61
 Identities = 248/1071 (23%), Positives = 420/1071 (39%), Gaps = 153/1071 (14%)

Query: 294   VKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRAS 353
             V+L   IAG P P  +W+     +       +  +E+   +  L I      DT +Y   
Sbjct: 29756 VELVIPIAGRPPPAASWFFAGSKLR---ESERVTVETHTKVAKLTIRETTIRDTGEYTLE 29812

Query: 354   AMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDV 413
               NV G  S    V++    G                     P G     EI   D   +
Sbjct: 29813 LKNVTGTTSETIKVIILDKPGP--------------------PTGPIKIDEI---DATSI 29849

Query: 414   SFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLN 473
             +   E   +  G      P   +   +   +R G       W+    S  R+T  F+ L 
Sbjct: 29850 TISWEPPELDGGA-----PLSGYVVEQRDAHRPG-------WLPVSESVTRSTFKFTRLT 29897

Query: 474   KEDEGLYTI----RVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIIS 529
             + +E ++ +    R  +G Y +       V +  + I   P  P  ++  + ++D + ++
Sbjct: 29898 EGNEYVFRVAATNRFGIGSYLQSE-----VIECRSSIR-IPGPPETLQIFDVSRDGMTLT 29951

Query: 530   WKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNK 589
             W  P  DGGS + GY +++ EV  D W + N  PV   R+  TGL EG  Y  RV A+N 
Sbjct: 29952 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 30011

Query: 590   MGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEA 649
              G G PSR S+P+ A+DP           AP                 PG P +  VT+ 
Sbjct: 30012 RGSGKPSRPSKPIVAMDPI----------AP-----------------PGKPQNPRVTDT 30044

Query: 650   TRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSY 708
             TR+ V L+W  P   G   +  Y +E  +     W + NT  P K   + L  L +G  Y
Sbjct: 30045 TRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTT-PTKIREYTLTHLPQGAEY 30103

Query: 709   CFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKEL 768
              FRV   N+ G GEP+E      V + L+ P            D  +   ++E    ++ 
Sbjct: 30104 RFRVLACNAGGPGEPAEVPGTVKVTEMLEYP------------DYELDERYQEGIFVRQ- 30150

Query: 769   VGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLV-TGQSYIFRVRAVNAAGLS------- 820
              G  I  ++   GK  P      +G   +   ++ T +++   V      G S       
Sbjct: 30151 -GGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVL 30209

Query: 821   EYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPN 880
             E     +A+ +K  + G  +    P   D+   +     RV    P       +LG    
Sbjct: 30210 ENKCGKKAVYIKVRVIGSPNSPEGPLEYDD---IQVRSVRVSWRPPADDGGADILGYILE 30266

Query: 881   KPSLPSSSQNLGQTEVSKVSETVQE---------ELTPPPQKAAPQGKSKSDPLKKKTDR 931
             +  +P ++     + V   S  V+           ++   Q    +     +P+  KT  
Sbjct: 30267 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 30326

Query: 932   APPSPPCDIT-CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKA 990
              PP PP +    L+  + S+ L W +P   GG+ +TGYY+  +E       KW   N   
Sbjct: 30327 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKET---STDKWVRHNKTQ 30383

Query: 991   VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEV 1050
             ++   Y ++ L  +  YQF++ A N  GL   S  SE   C++     P  P  L+   +
Sbjct: 30384 ITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD-PFDKPSQPGELEILSI 30442

Query: 1051  RKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVS 1110
              KDS+ LQW+ P   G   + GY+V+ ++  + +  W+  N+  IK+    + GL E   
Sbjct: 30443 SKDSVTLQWEKPECDGGKEILGYWVEYRQ--SGDSAWKKSNKERIKDKQFTIGGLLEATE 30500

Query: 1111  YVFRVRAINQAGVGKPSDLAGPV----VAETRPGTKEVVVNVDDDGVISLNFECDKM-TP 1165
             Y FRV A N+ G+ +P   A  +     +   PG ++ + +V      +    C  +  P
Sbjct: 30501 YEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRP 30560

Query: 1166  KSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLID 1225
               +  W +       S + ++ S G    +T      +D G+Y+C       IA++ + +
Sbjct: 30561 LPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC-------IATNEVGE 30613

Query: 1226  EEELKRLLALSHEHKFPTVPVK--------SELAVEILEKGQ---VRFWMQAEKLSGNAK 1274
              E   +LL  +     P  P+K        S L + ++  G+      W   +KL  N++
Sbjct: 30614 VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 30673

Query: 1275  VNYIFNEKEI-----------FEGPKYKMHIDRNTGIIEMFME-KLQDEDE 1313
                I N +                 KYK+ +    G ++  ++ ++QD+ +
Sbjct: 30674 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPD 30724



 Score =  234 bits (597), Expect = 5e-61
 Identities = 319/1304 (24%), Positives = 521/1304 (39%), Gaps = 194/1304 (14%)

Query: 273   LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY 332
             L+  P F +   + TV   E++K+     G P P VTW+K+ VP+       +   ES  
Sbjct: 22144 LVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK---QTTRVNAESTE 22200

Query: 333   GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKG------EFDETRFHAGAS 386
                 L I     ED   Y     N  GE     +V+V    G      + DE      A 
Sbjct: 22201 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVT----AD 22256

Query: 387   TMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRN 446
             ++ LS+G   Y   S    +  +K D S                                
Sbjct: 22257 SITLSWGPPKYDGGSSINNYIVEKRDTS-------------------------------- 22284

Query: 447   GVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAE- 505
                   + W     +  R T+    L    E  Y  R+     Y + S Y+      A+ 
Sbjct: 22285 -----TTTWQIVSATVARTTIKACRLKTGCE--YQFRIAAENRYGK-STYLNSEPTVAQY 22336

Query: 506   ---IEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDT 562
                + G P  P+      +++D + + W +P  DGGS ++GY +++ E  +  W + N T
Sbjct: 22337 PFKVPGPPGTPVVTL---SSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKT 22393

Query: 563   PVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWT 622
             P+   +F  TGL EG  Y FRV A N +GIG PS+VSE   A DP +             
Sbjct: 22394 PIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDP------------ 22441

Query: 623   GQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTE 681
                            PG P  + VT   R+ V L WK P   G   I  Y VEK E    
Sbjct: 22442 ---------------PGRPEAIIVT---RNSVTLQWKKPTYDGGSKITGYIVEKKELPEG 22483

Query: 682   NWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV-GEPSEATEVTVVGDKLDIPK 740
              W + +    + +  F +  L E   Y FRV   N+AGV  EPSE+T      D++D P+
Sbjct: 22484 RWMKASFTNIIDT-HFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 22542

Query: 741   APGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNN--PVKGSRF-- 796
                  +  +  DT VV + E  K   ++ G  I       G  E  N     +K + F  
Sbjct: 22543 IS---MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFAT 22599

Query: 797   --TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGL 854
               +    V   S  + ++A N AG     + S  + VK     G  P   P +     G+
Sbjct: 22600 SLSVKDAVRVDSGNYILKAKNVAG-----ERSVTVNVKVLDRPG--PPEGPVVIS---GV 22649

Query: 855   TASRGRVHEASPPTFQKDA------LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQ-EEL 907
             TA +  +  A  P  Q         ++  +     + +      QT   KV++ ++  E 
Sbjct: 22650 TAEKCTL--AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEY 22707

Query: 908   TPPPQKAAPQGKSK---SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
             T         G  +   S+P+  K     P  P         +DSM++ W++P   GG+E
Sbjct: 22708 TFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSE 22767

Query: 965   ITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSA 1024
             I GY +  R+  +G+  +W   + + + E   +++ L EN  Y+F+V+A N AGL  PS 
Sbjct: 22768 ILGYVLEKRDK-EGI--RWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSP 22824

Query: 1025  VSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE 1084
              S   K  +  I  PGPP++ K  ++ + S+ L W  P++ G   + GY V+  +    E
Sbjct: 22825 PSAYQKACD-PIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGE 22883

Query: 1085  DQWRGLNE-AAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKE 1143
               W        I    ++V  L E   Y FR+ AIN+AGVG+ +D+ GP++ E +    +
Sbjct: 22884 --WTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPD 22941

Query: 1144  V--------VVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKM 1195
             +        ++N+   G + L F   K  P  E  W K      D+  ++V S  + T +
Sbjct: 22942 IDLDLELRKIINIRAGGSLRL-FVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSL 22998

Query: 1196  TFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEIL 1255
                ++   D G Y+  + ++ G  S+++       R+L        P+ PV   L V  +
Sbjct: 22999 VLDNVNRYDSGKYTLTLENSSGTKSAFV-----TVRVL------DTPSPPV--NLKVTEI 23045

Query: 1256  EKGQVRFWMQAEKLSGNAKV-NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEG 1314
              K  V    +   L G +K+ NYI  ++E     K    +  N       +++LQ   EG
Sbjct: 23046 TKDSVSITWEPPLLDGGSKIKNYIVEKREATR--KSYAAVVTNCHKNSWKIDQLQ---EG 23100

Query: 1315  -TYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECN 1373
              +Y F++    A N   + L       + K AE           P     ++ +     +
Sbjct: 23101 CSYYFRV---TAENEYGIGLPAQTADPI-KVAEV----------PQPPGKITVDDVTRNS 23146

Query: 1374  VLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTL--LITEFSKKDAGIYEVILK 1431
             V L          + I+ Y  E +    EK      + +L  +IT  ++ +  ++ V+  
Sbjct: 23147 VSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAV 23206

Query: 1432  DDRGKDKSRLKLVDEAFKELMMEVCKKIALSA------TDLKIQSTAEGIQLYSFVTYYV 1485
             +++G+   R   V    K+L++E   K A S+       DLKI+    G    +      
Sbjct: 23207 NEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPT------ 23260

Query: 1486  EDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY 1529
                 + W+ +G  ++ + R+    + +   L I E   +D G+Y
Sbjct: 23261 ----ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 23300



 Score =  233 bits (595), Expect = 9e-61
 Identities = 261/1020 (25%), Positives = 403/1020 (39%), Gaps = 115/1020 (11%)

Query: 237   EKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKL 296
             E+K R  ++  K  +  +  T  + +     +  +  ++A   +   ++    E    + 
Sbjct: 23460 ERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARD 23519

Query: 297   HCSIAGWPEPRVTWYKNQVPIN----VHANPGK---YIIESRYGMHTLEINGCDFEDTAQ 349
              C   G PEP +   +N++ +     V+        YI+E R           D  D   
Sbjct: 23520 PCDPPGTPEP-IMVKRNEITLQWTKPVYDGGSMITGYIVEKR-----------DLPDGRW 23567

Query: 350   YRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFE---IH 406
              +AS  NV  E     S + +  + EF     +A  +    S    P       E   I 
Sbjct: 23568 MKASFTNVI-ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRIS 23626

Query: 407   FDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERA 465
              D KF D      GET  L   V   P      P I+W R    +  S   +   +  +A
Sbjct: 23627 MDPKFRDTIVVNAGETFRLEADVHGKP-----LPTIEWLRGDKEIEESARCEIKNTDFKA 23681

Query: 466   TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
              L      + D G Y +R       + +   V V D      G P  P+ V  + + K  
Sbjct: 23682 LLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQVTGVTSEK-- 23735

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
               ++W  P  DGGS I  Y ++K E    +W+      V  +   VT L+EG  Y+FR+ 
Sbjct: 23736 CSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNS-LKVTKLLEGNEYVFRIM 23794

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             AVNK G+G P   S PV   +P                            ++PGPP  L 
Sbjct: 23795 AVNKYGVGEPLE-SAPVLMKNPF---------------------------VLPGPPKSLE 23826

Query: 646   VTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAE 704
             VT   +  + + W +P    G E I Y VEK +     W + N    +   R  +  L E
Sbjct: 23827 VTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRR-ITDLRLRVTGLTE 23885

Query: 705   GKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-- 762
                Y FRV   N+AGVGEPS AT      D +  P  P        T  S+ ++W +   
Sbjct: 23886 DHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIY 23945

Query: 763   KDAKELVGYYIEASVAGSGKWEPCN-NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSE 821
                 E++GY +E   A   +W+       ++ +RF    L   Q Y  RV A+N  GL E
Sbjct: 23946 DGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGE 24005

Query: 822   YSQDSEAIEVKAAIGGGVSPD---VCPAL---SDEPGGLTASRG---RVH---EASP-PT 868
                         ++ G V P+     P L   S+   G+    G   R+H   +  P P 
Sbjct: 24006 ----------ATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPE 24055

Query: 869   FQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKK 928
                    G   +K  +    + +  T++S +    + +      K      SKS  +  K
Sbjct: 24056 ITWSREEGEFTDKVQI---EKGVNYTQLS-IDNCDRNDAGKYILKLENSSGSKSAFVTVK 24111

Query: 929   TDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
                  P PP ++   E  +DS  L W+ P   GGA++  Y ++ RE       +   ANV
Sbjct: 24112 V-LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE-----STRKAYANV 24165

Query: 989   KA-VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKC 1047
              +  S+ ++K+ NL E  +Y F+V A N  G+G P    +  K  E     P PP  +  
Sbjct: 24166 SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAE----PPSPPGKVTL 24221

Query: 1048  SEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKE 1107
             ++V + S  L W+ P H G + V GY V+++      ++W  + E+ + N    V GL  
Sbjct: 24222 TDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGT--EKWSIVAESKVCNAV--VTGLSS 24277

Query: 1108  GVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVVNVDDDGVISLNFECDKM- 1163
             G  Y FRV+A N+ G   P  L  PV+A+    +P  K             L  E   + 
Sbjct: 24278 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIG 24337

Query: 1164  TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
              P+   SW KD    + + R+ VE     T +  K+   DD G Y+   T++ G A+  L
Sbjct: 24338 RPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENL 24397



 Score =  233 bits (594), Expect = 1e-60
 Identities = 253/971 (26%), Positives = 389/971 (40%), Gaps = 143/971 (14%)

Query: 290   EKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQ 349
             E  N +L   I G P P V+W K + P+   A   +  +ES     TL +  C   D  +
Sbjct: 19996 ENSNFRLKIPIKGKPAPSVSWKKGEDPL---ATDTRVSVESSAVNTTLIVYDCQKSDAGK 20052

Query: 350   YRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFG-VTPYGYASRFEIHFD 408
             Y  +  NV G      S+ V              G  T P+ F  VT      ++    D
Sbjct: 20053 YTITLKNVAGTKEGTISIKVVG----------KPGIPTGPIKFDEVTAEAMTLKWAPPKD 20102

Query: 409   DKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLT 468
             D      G E           IT  I   +  +           +KWV    + ++ T  
Sbjct: 20103 DG-----GSE-----------ITNYILEKRDSVN----------NKWVTCASAVQKTTFR 20136

Query: 469   FSHLNKEDEGLYTIRVRMGEYY---EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
              + L++  E  YT RV     Y   E   +   V     ++  AP  P     ++   D 
Sbjct: 20137 VTRLHEGME--YTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPP---NIVDVRHDS 20191

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
             + ++W  P   GGSPI GY ++  E  +  W + N TP++   F VTGL EG  Y FRV 
Sbjct: 20192 VSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVM 20251

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             A+N  G+G PS  SEPV ALDP +                              PP    
Sbjct: 20252 AINLAGVGKPSLPSEPVVALDPID------------------------------PPGKPE 20281

Query: 646   VTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAE 704
             V   TR+ V L W +P    GH+   Y VEK +  +++W + N  + V    F + DL E
Sbjct: 20282 VINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKAN-HVNVPECAFTVTDLVE 20340

Query: 705   GKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESK 763
             G  Y FR+R  N+AG +  PSE+TE  +  D+ +   AP  ++     D   +    ++ 
Sbjct: 20341 GGKYEFRIRAKNTAGAISAPSESTETIICKDEYE---APTIVLDPTIKDGLTI----KAG 20393

Query: 764   DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823
             D   L    I         W     + ++ S  T     T  S +  ++        EY+
Sbjct: 20394 DTIVLNAISILGKPLPKSSWSKAGKD-IRPSDIT-QITSTPTSSMLTIKYATRKDAGEYT 20451

Query: 824   QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPS 883
                  I      G  V   V   + D PG      G V E S  + +K  L  + P +  
Sbjct: 20452 -----ITATNPFGTKVE-HVKVTVLDVPG----PPGPV-EISNVSAEKATLTWTPPLEDG 20500

Query: 884   -LPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQ-----------------GKSK---S 922
               P  S  L + E S++  TV  E     +  A +                 GK +   S
Sbjct: 20501 GSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQS 20560

Query: 923   DPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGK 982
             +P+K      PP PP         +++  + WK+P   GG+EITGY+V  RE       +
Sbjct: 20561 EPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSL---R 20617

Query: 983   WREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPP 1042
             W  A    VS+   K++ L+E   Y+F+V+A N AG+G PS  S+    ++     PGPP
Sbjct: 20618 WVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD-AAYPPGPP 20676

Query: 1043  HSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW-RGLNEAAIKNVYLK 1101
              +   ++  K S  L W  P + G   +TGY V+    K  ++ W +     A++     
Sbjct: 20677 SNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVE--HQKVGDEAWIKDTTGTALRITQFV 20734

Query: 1102  VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG---------TKEVVVNVDDDG 1152
             V  L+    Y FR+ AIN AGVG+P+ +    + E              + +VV     G
Sbjct: 20735 VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRA---G 20791

Query: 1153  VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
             +    F   K  P  E +W+KD ++ ++  R  +E+  + T +   +    D G +   +
Sbjct: 20792 LSIRIFVPIKGRPAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTGKFVMTI 20849

Query: 1213  TDTDGIASSYL 1223
              +  G  S ++
Sbjct: 20850 ENPAGKKSGFV 20860



 Score =  233 bits (593), Expect = 2e-60
 Identities = 236/910 (25%), Positives = 381/910 (41%), Gaps = 117/910 (12%)

Query: 404   EIHFDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG 462
             +I  D KF D    + GE   L   V   P      P ++W ++G  L  +  ++   + 
Sbjct: 21460 KIKVDVKFKDTVILKAGEAFRLEADVSGRPP-----PTMEWSKDGKELEGTAKLEIKIAD 21514

Query: 463   ERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEAN 522
                 L      + D G YT+       + ++   V V D      G P  PL V   E  
Sbjct: 21515 FSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRP----GPPEGPLAVT--EVT 21568

Query: 523   KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIF 582
              +  ++SW  P  DGG+ I  Y + K E    +W+    + V+  +  VT L++G  YIF
Sbjct: 21569 SEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIF 21627

Query: 583   RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
             RV AVNK G+G P   SEPV A++P                              P PP 
Sbjct: 21628 RVMAVNKYGVGEPLE-SEPVLAVNPYGP---------------------------PDPPK 21659

Query: 643   DLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFD 701
             +  VT  T+  +V+ W  P    G E I Y VE+ +   + W + N +  +   R+ +  
Sbjct: 21660 NPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT-LTDLRYKVSG 21718

Query: 702   LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEE 761
             L EG  Y FR+   N+AG+  PS  +      D +  P  PG       + +S+ ++W +
Sbjct: 21719 LTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNK 21778

Query: 762   S--KDAKELVGYYIEASVAGSGKWEPCNNNP-VKGSRFTCHGLVTGQSYIFRVRAVNAAG 818
                    E+ GY +E ++    +W+       +K + +T  GL   Q Y  R+ A+N+ G
Sbjct: 21779 PIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEG 21838

Query: 819   LSE--------YSQDS---EAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPP 867
             L E         ++D      IE+ A +   V+   C  L          +GR   A   
Sbjct: 21839 LGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRL----FVPIKGR--PAPEV 21892

Query: 868   TFQKDALLGSKPNKPSLPSSSQ-------NLGQTEVSKVSETVQEELTPPPQKAAPQGKS 920
              + +D   G   +K S+ S+S        N+ + +  K   TV+               S
Sbjct: 21893 KWARDH--GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENS-----------SGS 21939

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
             KS  +  +     P PP D+   E  + S+ L W  P   GG++I  Y V  RE      
Sbjct: 21940 KSAFVNVRV-LDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTR--- 21995

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
              K          + ++K+  L+E   Y F+V A N  G+G P+  +E  K  E     P 
Sbjct: 21996 -KAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASER----PL 22050

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYL 1100
             PP  +   +V ++S+ L W+ P H G + + GY V+++   +  D+W     A +K    
Sbjct: 22051 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGS--DKWATC--ATVKVTEA 22106

Query: 1101  KVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR--PGTKEVVVNV-----DDDGV 1153
              + GL +G  Y FRV A N+ G+  P  L+ PV+A+    P   +++ N       +D  
Sbjct: 22107 TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLK 22166

Query: 1154  ISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVT 1213
             + + F   + TP    +W KD V  + + R+  ES  N + +T KD   +D+G Y   +T
Sbjct: 22167 VDVPF-IGRPTPA--VTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLT 22223

Query: 1214  DTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
             ++ G A        E   ++ L      PT PVK +   E+        W   +   G++
Sbjct: 22224 NSAGEAI-------ETLNVIVLDKPGP-PTGPVKMD---EVTADSITLSWGPPKYDGGSS 22272

Query: 1274  KVNYIFNEKE 1283
               NYI  +++
Sbjct: 22273 INNYIVEKRD 22282



 Score =  232 bits (592), Expect = 2e-60
 Identities = 212/734 (28%), Positives = 309/734 (42%), Gaps = 93/734 (12%)

Query: 439   PEIQWYRNGVPLS-PSKWVQTLW-----SGERATLTFSHLNKEDEGLYTIRV--RMGEYY 490
             P+I+W +N   +  P+  +Q        S  +  L+     +ED+G YT+    R+G  +
Sbjct: 15428 PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVF 15487

Query: 491   EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCE 550
                      R+   E+   P+ P ++   +   +   ++W  P  +GGS I  Y IDK +
Sbjct: 15488 ---------RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRD 15538

Query: 551   VGTD--SWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPA 608
                    W +  +T V+  R+ +  LI    Y FRVRAVNK GI    + S+ V   DP 
Sbjct: 15539 ASRKKAEWEEVTNTAVE-KRYGIWKLIPNGQYEFRVRAVNKYGISDECK-SDKVVIQDPY 15596

Query: 609   EKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEG 668
                                         +PGPP    V   T+  +++SW PP   G   
Sbjct: 15597 R---------------------------LPGPPGKPKVLARTKGSMLVSWTPPLDNGGSP 15629

Query: 669   IM-YFVEKCEAGTENWQRVN----TELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEP 723
             I  Y++EK E G+  W RV+    T++ +K   F +  L EG  Y FR    N+AG+G P
Sbjct: 15630 ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPP 15689

Query: 724   SEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE-ESKD-AKELVGYYIEASVAGSG 781
             SE ++  V GD +  P  P        T +S+ + W+  +KD    + GY +E    G+ 
Sbjct: 15690 SEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTT 15749

Query: 782   KWEPCNNNPVKGSRFTCHGLVTG----QSYIFRVRAVNAAGLSEYSQDSEAI-------E 830
              W+   N P K    TC  +V      + Y FRV+AVN AG SE S  +  I       E
Sbjct: 15750 DWKRV-NEPDK-LITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEE 15807

Query: 831   VKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQN 890
              +  I  G    +      +       +GR    S   F   A    K     +P  +Q 
Sbjct: 15808 PEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQ- 15866

Query: 891   LGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAP---------PSPPCDIT 941
             L   E S V       +  P  K +  GK       K   +           P PP D+ 
Sbjct: 15867 LETAENSSV-------IIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK 15919

Query: 942   CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
               +  R S  L WK PD  GG  I GY +  R  IDG    W + N    S   + + +L
Sbjct: 15920 VSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR-TIDG--KAWTKVNPDCGS-TTFVVPDL 15975

Query: 1002  KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
                  Y F+V A N  G+G P    +     +  I  P PP  LK   + K+++ L WKP
Sbjct: 15976 LSEQQYFFRVRAENRFGIGPPVETIQRTTARD-PIYPPDPPIKLKIGLITKNTVHLSWKP 16034

Query: 1062  PVHSGRTPVTGYFVDL---KEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAI 1118
             P + G +PVT Y V+         K++ WR  N+  ++ +   V  L EG  Y FRV+A+
Sbjct: 16035 PKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAV 16094

Query: 1119  NQAGVGKPSDLAGP 1132
             N AGV KPS   GP
Sbjct: 16095 NAAGVSKPSATVGP 16108



 Score =  228 bits (582), Expect = 3e-59
 Identities = 213/797 (26%), Positives = 332/797 (41%), Gaps = 96/797 (12%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVR--MGEYYEQYSAY 496
             P+  W + G  + PS   Q   +   + LT  +  ++D G YTI      G   E     
Sbjct: 20409 PKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVT 20468

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             V       ++ G P  P+++  + A K    ++W  P  DGGSPI  Y ++K E     W
Sbjct: 20469 VL------DVPGPPG-PVEISNVSAEK--ATLTWTPPLEDGGSPIKSYILEKRETSRLLW 20519

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             +  ++  ++  R   T LI+G  YIFRV AVN  G G P + SEPV  +D       +  
Sbjct: 20520 TVVSED-IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVD-------RFG 20570

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
             P                    PGPP    V+  T++   +SWK P   G   I  Y VE+
Sbjct: 20571 P--------------------PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVER 20610

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  W R   + PV   R  +  L EG +Y FRV   N AG+G PSEA++  ++ D 
Sbjct: 20611 REKKSLRWVRA-IKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA 20669

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEESK--DAKELVGYYIEASVAGSGKW-EPCNNNPVK 792
                P  P     +  T  S  ++W +       E+ GY +E    G   W +      ++
Sbjct: 20670 AYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALR 20729

Query: 793   GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS--QDSEAIEVKAAIGGGVSPDVCPALSDE 850
              ++F    L T + Y FR+ A+N AG+ E +   D E +E + A    +  ++   L   
Sbjct: 20730 ITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVR 20789

Query: 851   PGG----LTASRGRVHEASPPTFQKDAL-LGSKPNKPSLPSSS----QNLGQTEVSKVSE 901
              G         +GR   A   T+ KD + L ++ N  +  S +        + +  K   
Sbjct: 20790 AGLSIRIFVPIKGR--PAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 20847

Query: 902   TVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIG 961
             T++           P GK       +  D   P P  ++   +  +DS+ L W  P   G
Sbjct: 20848 TIEN----------PAGKKSGFVNVRVLDT--PGPVLNLRPTDITKDSVTLHWDLPLIDG 20895

Query: 962   GAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGA 1021
             G+ IT Y V  RE        +  A  K   +  YK++ L E   Y F+V A N  G+G 
Sbjct: 20896 GSRITNYIVEKREA---TRKSYSTATTKC-HKCTYKVTGLSEGCEYFFRVMAENEYGIGE 20951

Query: 1022  PSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAK 1081
             P+  +E  K  E     P PP SL   ++ K ++ L W  P H G + +TGY ++ +  +
Sbjct: 20952 PTETTEPVKASE----APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQ--R 21005

Query: 1082  AKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGT 1141
                DQW  +    +K +   VR L EG  Y F+V A+N AG   P + + PV+ + +   
Sbjct: 21006 KGSDQWTHI--TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPVIVKEQTML 21062

Query: 1142  KE----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGN 1191
              E          V+    D+  + +        PK   +W K     + + R+  E+   
Sbjct: 21063 PELDLRGIYQKLVIAKAGDNIKVEIPV---LGRPKPTVTWKKGDQILKQTQRVNFETTAT 21119

Query: 1192  KTKMTFKDLGMDDLGIY 1208
              T +   +    D G Y
Sbjct: 21120 STILNINECVRSDSGPY 21136



 Score =  227 bits (579), Expect = 6e-59
 Identities = 229/893 (25%), Positives = 362/893 (40%), Gaps = 102/893 (11%)

Query: 425   GCRVVITPEIKHFQ-PEIQWYR-------NGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             G  V I  +IK    P + W++       N  P+     V  L   +  TL      + D
Sbjct: 16131 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 16190

Query: 477   EGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPA 534
              GLYTI     +G   ++    V  R       G P  P+  + + A  D + +SW  P 
Sbjct: 16191 TGLYTITAVNNLGTASKEMRLNVLGRP------GPPVGPIKFESVSA--DQMTLSWFPPK 16242

Query: 535   VDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGF 594
              DGGS I  Y I+K E    +W   +  P K   + +  L+EG  Y+FR+ A NK GIG 
Sbjct: 16243 DDGGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 16301

Query: 595   PSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYV 654
             P         LD           S P T + + +        VPG P   +V+  TR+ +
Sbjct: 16302 P---------LD-----------SEPETARNLFS--------VPGAPDKPTVSSVTRNSM 16333

Query: 655   VLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR----FALFDLAEGKSYC 709
              ++W+ P   G   +  Y++E  +  ++ W+RVN + P+K+      + +  L EG  Y 
Sbjct: 16334 TVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRD-PIKAMTLGVSYKVTGLIEGSDYQ 16392

Query: 710   FRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-KDA-KE 767
             FRV   N+AGVG  S  ++     D +  P  P   +    T +S  + W    KD   +
Sbjct: 16393 FRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW-TKSSADLEWSPPLKDGGSK 16451

Query: 768   LVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 827
             + GY +E    G  +WE   +  V+G++    GL  G  Y FRVRAVN AG+ E  + ++
Sbjct: 16452 VTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD 16511

Query: 828   AIEVKAAIGGGVSPD------VCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNK 881
              IE+K  +   VSPD      V   +    GG+      V    PPT   +    + P +
Sbjct: 16512 VIEMKDRL---VSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQE 16568

Query: 882   PSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDIT 941
              ++ +++  +  + V K  +   + +     K     + K+  +       P   P    
Sbjct: 16569 ATIETTA--ISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTP--FL 16624

Query: 942   CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
                   +S  L W  P+  GG+ IT Y +  RE        W         + A  +  L
Sbjct: 16625 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRE---SDRRAWTPVTYTVTRQNA-TVQGL 16680

Query: 1002  KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
              +   Y F++AA N  G+G     SE     E  I VP  P  L+  EV K+++ L W P
Sbjct: 16681 IQGKAYFFRIAAENSIGMGPFVETSEALVIRE-PITVPERPEDLEVKEVTKNTVTLTWNP 16739

Query: 1062  PVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA 1121
             P + G + +  Y ++       E   +  N+  +   Y  V+GLKEG +Y +RV A+N  
Sbjct: 16740 PKYDGGSEIINYVLE-SRLIGTEKFHKVTNDNLLSRKY-TVKGLKEGDTYEYRVSAVNIV 16797

Query: 1122  GVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMT------PKSEFSWSKDY 1175
             G GKPS    P+  +       + ++  D   I +  E   +T      PK + SW KD 
Sbjct: 16798 GQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVG-EAFALTGRYSGKPKPKVSWFKDE 16856

Query: 1176  VSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSY----LIDEEELKR 1231
                 +  R  +++      +        D G Y   V ++ G    +    ++D      
Sbjct: 16857 ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR----- 16911

Query: 1232  LLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEI 1284
                       P  PV      E+ +   V  W       G+   NYI  +KE+
Sbjct: 16912 ----------PGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEV 16954



 Score =  225 bits (574), Expect = 2e-58
 Identities = 218/877 (24%), Positives = 354/877 (40%), Gaps = 106/877 (12%)

Query: 367   VVVKRYKGEFDETRFHAGASTM-----PLSFGVTPYGYASRFEIHFDDKFDVSFGREGET 421
             V+ +   G F E     GA T      P    + P  Y     +H  + F V     G+ 
Sbjct: 22513 VIARNAAGVFSEPSESTGAITARDEVDPPRISMDPK-YKDTIVVHAGESFKVDADIYGKP 22571

Query: 422   MSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYT 481
             +                P IQW +    LS +  ++   +    +L+     + D G Y 
Sbjct: 22572 I----------------PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYI 22615

Query: 482   IRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPI 541
             ++ +        +  V V D      G P  P+ +  + A K    ++WK P  DGGS I
Sbjct: 22616 LKAKNVAGERSVTVNVKVLDRP----GPPEGPVVISGVTAEK--CTLAWKPPLQDGGSDI 22669

Query: 542   LGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEP 601
             + Y +++ E     W+   D  V+     VT L+EG  Y FR+ AVNK G+G P   SEP
Sbjct: 22670 INYIVERRETSRLVWTVV-DANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE-SEP 22727

Query: 602   VAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPP 661
             V A +P                            +VP  P    VT  T+  +++ W+ P
Sbjct: 22728 VVAKNPF---------------------------VVPDAPKAPEVTTVTKDSMIVVWERP 22760

Query: 662   GQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV 720
                G   I+ Y +EK +     W R +  L +   R  +  L E   Y FRV   N+AG+
Sbjct: 22761 ASDGGSEILGYVLEKRDKEGIRWTRCHKRL-IGELRLRVTGLIENHDYEFRVSAENAAGL 22819

Query: 721   GEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVA 778
              EPS  +      D +  P  P        T +SV +SW +       E+ GY +E    
Sbjct: 22820 SEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDV 22879

Query: 779   GSGKWEPCNN-NPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGG 837
               G+W  C     +  +      L+    Y FR+ A+N AG+ E++     I V+  +  
Sbjct: 22880 SVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEA 22939

Query: 838   ---GVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQ----- 889
                 +  ++   ++   GG       +     P  +   + G   +   +  +S      
Sbjct: 22940 PDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV 22999

Query: 890   --NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFR 947
               N+ + +  K + T++             G   +    +  D   PSPP ++   E  +
Sbjct: 23000 LDNVNRYDSGKYTLTLENS----------SGTKSAFVTVRVLDT--PSPPVNLKVTEITK 23047

Query: 948   DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY 1007
             DS+ + W+ P   GG++I  Y V  RE       K   A V    + ++KI  L+E   Y
Sbjct: 23048 DSVSITWEPPLLDGGSKIKNYIVEKREATR----KSYAAVVTNCHKNSWKIDQLQEGCSY 23103

Query: 1008  QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 1067
              F+V A N  G+G P+  ++  K  E    VP PP  +   +V ++S+ L W  P H G 
Sbjct: 23104 YFRVTAENEYGIGLPAQTADPIKVAE----VPQPPGKITVDDVTRNSVSLSWTKPEHDGG 23159

Query: 1068  TPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS 1127
             + +  Y V++ +AK  E +W     A +K++   +  L +G  Y+FRV A+N+ G   P 
Sbjct: 23160 SKIIQYIVEM-QAKHSE-KWSEC--ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPR 23215

Query: 1128  DLAGPVVA-------ETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTED 1180
              LA P+VA       + +P      V V  D  I +        PK   +W+KD +  + 
Sbjct: 23216 SLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG---RPKPTITWTKDGLPLKQ 23272

Query: 1181  SPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             + R+ V    + T ++ K+   DD G Y   V +  G
Sbjct: 23273 TTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG 23309



 Score =  224 bits (572), Expect = 4e-58
 Identities = 288/1312 (21%), Positives = 517/1312 (39%), Gaps = 206/1312 (15%)

Query: 276   APEFIIKP------RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIE 329
             A + +I+P       S++V   +++K+   I+G P+P +TW K+ +P+       +  + 
Sbjct: 23223 AKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK---QTTRINVT 23279

Query: 330   SRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRY----KG--EFDETRFHA 383
                 + TL I     +D  QY  +  NV G+ +A   +V        KG  +FD+     
Sbjct: 23280 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDV---- 23335

Query: 384   GASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQW 443
              A ++ LS+    Y    +   +   K D +                             
Sbjct: 23336 SAESITLSWNPPLYTGGCQITNYIVQKRDTT----------------------------- 23366

Query: 444   YRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV---FVR 500
                      + W     +  R TL  + L    E  Y  R+     Y Q  A      V 
Sbjct: 23367 --------TTVWDVVSATVARTTLKVTKLKTGTE--YQFRIFAENRYGQSFALESDPIVA 23416

Query: 501   DADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCN 560
                 +  G P  P        +KD ++I W +P  +GGSP++GY +++ E  +  W++ N
Sbjct: 23417 QYPYKEPGPPGTPF---ATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVN 23473

Query: 561   DTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAP 620
              T +   +F    L EG  Y FRV A N +G+G  S+ SE   A DP +           
Sbjct: 23474 KTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDP---------- 23523

Query: 621   WTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAG 679
                              PG P  + V    R+ + L W  P   G   I  Y VEK +  
Sbjct: 23524 -----------------PGTPEPIMVK---RNEITLQWTKPVYDGGSMITGYIVEKRDLP 23563

Query: 680   TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDI 738
                W + +    +++ +F +  L E + Y FRV   N+AG + +PS++T      D++++
Sbjct: 23564 DGRWMKASFTNVIET-QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVEL 23622

Query: 739   PKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEAS--VAGSGKWEPCNNNPVKGSRF 796
             P+     +  +  DT VV + E  +   ++ G  +     + G  + E      +K + F
Sbjct: 23623 PRIS---MDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 23679

Query: 797   TCHGLVT------GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGG-----GVSPDVC- 844
                 +V       G  YI  +RA N AG   +  + + ++      G     GV+ + C 
Sbjct: 23680 KALLIVKDAIRIDGGQYI--LRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 23737

Query: 845   ----PALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVS 900
                 P L D  GG   S   V +          ++ S+    SL  +    G   V ++ 
Sbjct: 23738 LTWSPPLQD--GGSDISHYVVEKRETSRLAW-TVVASEVVTNSLKVTKLLEGNEYVFRIM 23794

Query: 901   ETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKI 960
                +  +  P + A         P+  K     P PP  +      +DSM + W +PD  
Sbjct: 23795 AVNKYGVGEPLESA---------PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSD 23845

Query: 961   GGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLG 1020
             GG+EI GY V  R+   G+  +W + N + +++   +++ L E+  Y+F+V+A N AG+G
Sbjct: 23846 GGSEIIGYIVEKRD-RSGI--RWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVG 23902

Query: 1021  APSAVSECFK-CEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
              PS  +  +K C+   +  PGPP +    +  K+S+ L W  P++ G + + GY V++  
Sbjct: 23903 EPSPATVYYKACD--PVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEI-- 23958

Query: 1080  AKAKEDQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR 1138
              KA E++W+ +  +  ++    ++  L E   Y  RV A+N+ G+G+ + + G V  E +
Sbjct: 23959 CKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDK 24018

Query: 1139  PGTKE----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVES 1188
                 E          +VV       I + F   K  P  E +WS++    E + ++++E 
Sbjct: 24019 LEAPELDLDSELRKGIVVRAGGSARIHIPF---KGRPTPEITWSRE--EGEFTDKVQIEK 24073

Query: 1189  KGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKS 1248
               N T+++  +   +D G Y   + ++ G  S+++  +                T     
Sbjct: 24074 GVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVK-------------VLDTPGPPQ 24120

Query: 1249  ELAVEILEKGQVRFWMQAEKLSGNAKV-NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEK 1307
              LAV+ + K       +   + G AKV NY+ +++E     K   ++          +E 
Sbjct: 24121 NLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE--STRKAYANVSSKCSKTSFKVEN 24178

Query: 1308  LQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWE 1367
             L   +   Y F++           V   D  K  +               P     ++  
Sbjct: 24179 L--TEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP--------------PSPPGKVTLT 24222

Query: 1368  VTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGI 1425
                + +  L  +       + ++ Y  E +    EK     +  +C  ++T  S      
Sbjct: 24223 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 24282

Query: 1426  YEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIAL------SATDLKIQSTAEGIQLYS 1479
             + V   +++GK   R+  V    K+L ++   K+        +  DLKI+    G    +
Sbjct: 24283 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN 24342

Query: 1480  FVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
                       ++W  +G  ++ + RV    T     L I E   +D GKY +
Sbjct: 24343 ----------ISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 24384



 Score =  219 bits (558), Expect = 2e-56
 Identities = 202/716 (28%), Positives = 292/716 (40%), Gaps = 101/716 (14%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTP-VKFAR 568
             P  P + + L+ ++  I I+W +P  DGGS I GY ++      D W        +K   
Sbjct: 21756 PGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATS 21815

Query: 569   FPVTGLIEGRSYIFRVRAVNKMGIGFPS----------RVSEPVAALD------------ 606
             + +TGL E + Y  R+ A+N  G+G P+          R+  P   LD            
Sbjct: 21816 YTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRAC 21875

Query: 607   ------------PA-------------EKARLKSRPSAPW----------TGQIIVTEEE 631
                         PA             +KA ++S  S             +G+ I+T E 
Sbjct: 21876 CTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVEN 21935

Query: 632   PSEGI----------VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGT 680
              S              PGPP DL V E T++ V L+W PP   G   I  Y VEK E+  
Sbjct: 21936 SSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTR 21995

Query: 681   ENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
             + +  V T     S  + +  L EG SY FRV   N  G+G P+E  E     ++   P 
Sbjct: 21996 KAYSTVATNCHKTS--WKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASER---PL 22050

Query: 741   APGKIIPSRNTDTSVVVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTC 798
              PGKI     T  SV +SWE  E      ++GY +E    GS KW  C    VK +  T 
Sbjct: 22051 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCAT--VKVTEATI 22108

Query: 799   HGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASR 858
              GL+ G+ Y FRV A N  G+S+  Q S  +  K  +       + PA        T   
Sbjct: 22109 TGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV-------IPPAFKLLFNTFTVLA 22161

Query: 859   GRVHEASPPTFQK--DALLGSKPNKPSLPSSSQNLGQTE---VSKVSETVQEELTPPPQK 913
             G   +   P   +   A+   K N P   ++  N   TE   +  + +  +E++     K
Sbjct: 22162 GEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVK 22221

Query: 914   AAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYR 973
                      + L       P  P   +   E   DS+ L W  P   GG+ I  Y V  R
Sbjct: 22222 LTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKR 22281

Query: 974   EVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE 1033
                D     W+  +   V+    K   LK    YQF++AA N    G  + ++      +
Sbjct: 22282 ---DTSTTTWQIVSA-TVARTTIKACRLKTGCEYQFRIAAENR--YGKSTYLNSEPTVAQ 22335

Query: 1034  WTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
             +   VPGPP +   +   +DS+ +QW  P+  G + V GY ++ KE  +    W  LN+ 
Sbjct: 22336 YPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNS--ILWVKLNKT 22393

Query: 1094  AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVV 1146
              I     K  GL+EGV Y FRV A N  G+GKPS ++   VA      PG  E ++
Sbjct: 22394 PIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAII 22449



 Score =  219 bits (557), Expect = 2e-56
 Identities = 204/808 (25%), Positives = 322/808 (39%), Gaps = 89/808 (11%)

Query: 439   PEIQWYRN--GVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAY 496
             PE+ W ++     L+ S  V+     + +  + +   + D G Y +           +A 
Sbjct: 18231 PEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATN-------TAG 18283

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
              FV  A   +   P    ++K ++ + D   + W  P  DGG  I  Y ++KCE     W
Sbjct: 18284 SFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW 18343

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             S  + T V      VT LIEG  YIFRVRA NK+G G P+  S+PV A    +K      
Sbjct: 18344 STYSAT-VLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTE-SKPVIAKTKYDK------ 18395

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
                                  PG P    VT+ ++  + + W PP   G + I  YF+EK
Sbjct: 18396 ---------------------PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEK 18434

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  W  VN +  +   R  + +L     Y FRV+  N  G+GEPS  +   V  D 
Sbjct: 18435 KEKHSTRWVPVN-KSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDP 18493

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIE-----ASVAGSGKWEPCN- 787
             ++ P  P        T  S+ + W +        ++GY +E     A  +    W+ CN 
Sbjct: 18494 IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNA 18553

Query: 788   NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPAL 847
                +    FT   L   Q Y FRV A N  G+   ++  EAI+ K  +     P++    
Sbjct: 18554 AAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEIL---EPPEI---- 18606

Query: 848   SDEPGGLTASRGR--VHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSET--- 902
                   L AS  +  +  A  P      L      +P+   + + +G   V +  +    
Sbjct: 18607 -----DLDASMRKLVIVRAGCPI----RLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLV 18657

Query: 903   -VQEELTPPPQKAAPQGKSKSDPLKKKTDRA---------PPSPPCDITCLESFRDSMVL 952
                  L  P       GK     +    ++A          P P  D+   +  + S  +
Sbjct: 18658 DTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHV 18717

Query: 953   GWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVA 1012
              W  P+  GG+++T Y V  RE       K        V + ++ ++NL     Y F+V 
Sbjct: 18718 SWAPPENDGGSQVTHYIVEKRE----ADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVT 18773

Query: 1013  AMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTG 1072
             A+N  G G P+ V +     +  ++ P PP  L+ +E+ K+S  L W PP+  G   + G
Sbjct: 18774 AVNEYGPGVPTDVPKPVLASD-PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 18832

Query: 1073  YFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGP 1132
             Y    +E +   D+W     + +K++ L V GLKEG  Y FRV A N  GV  P +  G 
Sbjct: 18833 YITSYREEEQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGV 18890

Query: 1133  VVAETRPGTKEVVV--NVDDDGVISLNFECDKM-TPKSEFSWSKDYVSTEDSPRLEVESK 1189
               A+ +    ++++   +       L  E      P     W K       S  L V   
Sbjct: 18891 YEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKA 18950

Query: 1190  GNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
              + + +  KD+   D G YS    ++ G
Sbjct: 18951 DSSSILIIKDVTRKDSGYYSLTAENSSG 18978



 Score =  216 bits (551), Expect = 1e-55
 Identities = 206/784 (26%), Positives = 323/784 (41%), Gaps = 104/784 (13%)

Query: 475   EDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPA 534
             ED G+Y++ V      +  S  V V D        P  P D++  E  KD   ++WK+P 
Sbjct: 17282 EDGGIYSLTVENPAGSKTVSVKVLVLDK-------PGPPRDLEVSEIRKDSCYLTWKEPL 17334

Query: 535   VDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGF 594
              DGGS I  Y +++ +V +  WS  + T  K + F    L EG  Y+FRV A N+ G G 
Sbjct: 17335 DDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAENQYGRGP 17393

Query: 595   PSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYV 654
                  +P+ ALDP                              PGPP DL   +  ++ V
Sbjct: 17394 FVETPKPIKALDPLHP---------------------------PGPPKDLHHVDVDKTEV 17426

Query: 655   VLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVR 713
              L W  P + G   I  Y VE  E GT++W +  T   V +    +  L +GK+Y FRV+
Sbjct: 17427 SLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKT---VTNLECVVTGLQQGKTYRFRVK 17483

Query: 714   CSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYI 773
               N  G+G P   T + +   +  +P       PS   D  ++                I
Sbjct: 17484 AENIVGLGLPD--TTIPIECQEKLVP-------PSVELDVKLIEGLVVKAGTTVRFPAII 17534

Query: 774   EASVAGSGKWEPCNNNPVKGSRFT--------------CHGLVTGQSYIFRVRAVNAAGL 819
                   + KW    +       +T              C    TG+   +++   NAAG 
Sbjct: 17535 RGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGE---YQITVSNAAGS 17591

Query: 820   SEYSQDSEAIEVKAAIGGGVSP-DVCP---ALSDEP----GGLTASRGRVHEASPPTFQK 871
                +     ++V     G ++  DV P    +S +P    GG       V +      +K
Sbjct: 17592 KTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDT---RK 17648

Query: 872   DA--LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKT 929
             D   ++ S  +K  L       G   V +V    +  + PP           S P   K 
Sbjct: 17649 DTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLD---------STPTVAKH 17699

Query: 930   DRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVK 989
               +PPSPP      +   ++  + W  P   GG+ ITGYY+  RE    V GKW   N  
Sbjct: 17700 KFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERRE----VTGKWVRVNKT 17755

Query: 990   AVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK-CEEWTIAVPGPPHSLKCS 1048
              +++  ++++ L E   Y+F+V A N+AGL  PS  S+  K C    I  PGPP + K  
Sbjct: 17756 PIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACR--PIKPPGPPINPKLK 17813

Query: 1049  EVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRGLKE 1107
             +  +++  L W  P+  G +P+ GY V+ +  K    QW  +N +  I+    +V GL E
Sbjct: 17814 DKSRETADLVWTKPLSDGGSPILGYVVECQ--KPGTAQWNRINKDELIRQCAFRVPGLIE 17871

Query: 1108  GVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN-------FEC 1160
             G  Y FR++A N  G G+P +LA  V+A+      EV ++V    VI++           
Sbjct: 17872 GNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILAR 17931

Query: 1161  DKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
              K  P+ + +W+K+        R+++     + ++  K+    D G Y     ++ G A 
Sbjct: 17932 VKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQ 17991

Query: 1221  SYLI 1224
                I
Sbjct: 17992 GSAI 17995



 Score =  216 bits (550), Expect = 1e-55
 Identities = 215/827 (25%), Positives = 330/827 (39%), Gaps = 99/827 (11%)

Query: 417   REGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             R G TM L   V   P      P+I W +  V L     +    +     L   ++NK D
Sbjct: 19706 RAGVTMRLYVPVKGRPP-----PKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYD 19760

Query: 477   EGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVD 536
              G Y + +      ++Y+  V V D        P  P++V   E +KD   ++W+ P +D
Sbjct: 19761 AGKYILTLENSCGKKEYTIVVKVLDT-------PGPPVNVTVKEISKDSAYVTWEPPIID 19813

Query: 537   GGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPS 596
             GGSPI+ Y + K +    SWS    T      F V  L EG+SY FRV A N+ GIG P 
Sbjct: 19814 GGSPIINYVVQKRDAERKSWSTVT-TECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPG 19872

Query: 597   RVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVL 656
                + V A                                 PGP  DL V   ++S   +
Sbjct: 19873 ETRDAVKASQ------------------------------TPGPVVDLKVRSVSKSSCSI 19902

Query: 657   SWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSN 716
              WK P   G   I+ +V         WQRV   L   S +++  DL EGK Y FRV   N
Sbjct: 19903 GWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSL---SLQYSAKDLTEGKEYTFRVSAEN 19959

Query: 717   SAGVGEPSEATEVT---VVGDKLDIPKAPGKIIPSRNTDT-----------SVVVSWEES 762
               G G PSE T V    VV   LD+   P     ++               +  VSW++ 
Sbjct: 19960 ENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG 20019

Query: 763   KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEY 822
             +D        +      S +    N   +    + C     G+   + +   N AG  E 
Sbjct: 20020 EDP-------LATDTRVSVESSAVNTTLIV---YDCQKSDAGK---YTITLKNVAGTKE- 20065

Query: 823   SQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKP 882
                + +I+V    G    P     ++ E   L  +  +    S  T        S  NK 
Sbjct: 20066 --GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKW 20123

Query: 883   SLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-KSDPLKKKTDRAPPSPPCDIT 941
                +S+       V+++ E ++       +     G+  KS+P+  +     P  P    
Sbjct: 20124 VTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPN 20183

Query: 942   CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
              ++   DS+ L W  P K GG+ ITGY++ ++E    +   W+ AN   +    +K++ L
Sbjct: 20184 IVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL---WKRANKTPIRMRDFKVTGL 20240

Query: 1002  KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
              E + Y+F+V A+N+AG+G PS  SE     +  I  PG P  +    + ++S+ L W  
Sbjct: 20241 TEGLEYEFRVMAINLAGVGKPSLPSEPVVALD-PIDPPGKPEVI---NITRNSVTLIWTE 20296

Query: 1062  PVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA 1121
             P + G   +TGY V+ ++  +K   W   N   +      V  L EG  Y FR+RA N A
Sbjct: 20297 PKYDGGHKLTGYIVEKRDLPSK--SWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 20354

Query: 1122  G-VGKPSDLAGPVVAETR---------PGTKE-VVVNVDDDGVISLNFECDKMTPKSEFS 1170
             G +  PS+    ++ +           P  K+ + +   D  V++      K  PKS  S
Sbjct: 20355 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKS--S 20412

Query: 1171  WSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             WSK       S   ++ S    + +T K     D G Y+   T+  G
Sbjct: 20413 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 20459



 Score =  216 bits (550), Expect = 1e-55
 Identities = 203/835 (24%), Positives = 345/835 (41%), Gaps = 98/835 (11%)

Query: 411   FDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFS 470
             FD    + GE++ +   V   P      P + W+++GV +     ++        +L   
Sbjct: 27965 FDGLIIKSGESLRIKALVQGRPV-----PRVTWFKDGVEIEKRMNMEITDVLGSTSLFVR 28019

Query: 471   HLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISW 530
                ++  G+YT+  +      +    V V+D   ++ G       ++      + + + W
Sbjct: 28020 DATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGP------IRFTNITGEKMTLWW 28073

Query: 531   KQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKM 590
               P  DG +PI  Y I+K E    +W+   D   +   +    LI G  Y FRV AVNK 
Sbjct: 28074 DAPLNDGCAPITHYIIEKRETSRLAWALIEDK-CEAQSYTAIKLINGNEYQFRVSAVNKF 28132

Query: 591   GIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEAT 650
             G+G P   S+PV A                   QI  T        VP  P     +  T
Sbjct: 28133 GVGRPLD-SDPVVA-------------------QIQYT--------VPDAPGIPEPSNIT 28164

Query: 651   RSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYC 709
              + + L+W +P    G E   Y +E+ E  +  W +V ++ P+   RF +  L EG  Y 
Sbjct: 28165 GNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYE 28224

Query: 710   FRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKE 767
             F V   N+AGVG  S  + +    + ++ P  P  +  +  + T+V + W +       E
Sbjct: 28225 FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGME 28284

Query: 768   LVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 827
             ++GY IE   A  G W   N      +R+T   L  G+ Y FRV A+N AG  +  + + 
Sbjct: 28285 IIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTG 28344

Query: 828   AIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV-----HEASP-PT---FQKDALLGSK 878
              I+   A+    +P++    + +   +  +   +     ++  P PT    + D+ L  +
Sbjct: 28345 TIK---AVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLR 28401

Query: 879   PNKPSLPSSS----QNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPP 934
              +  +  S S    +N  + +  K + TV+               SKS     K     P
Sbjct: 28402 ADIHTTDSFSTLTVENCNRNDAGKYTLTVEN-----------NSGSKSITFTVKV-LDTP 28449

Query: 935   SPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEE 994
              PP  IT  +  R S  L W  P   GGA I  Y V  RE        W+  + K  + +
Sbjct: 28450 GPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKRE---ASRRSWQVISEKC-TRQ 28505

Query: 995   AYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDS 1054
              +K+++L E + Y F+V+A+N  G+G P  + E     E     P PP  L   +  K S
Sbjct: 28506 IFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATE----QPAPPRRLDVVDTSKSS 28561

Query: 1055  LVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFR 1114
              VL W  P H G + +TGY +++++  +  D W  +     K +   V  L E   Y FR
Sbjct: 28562 AVLAWLKPDHDGGSRITGYLLEMRQKGS--DFW--VEAGHTKQLTFTVERLVEKTEYEFR 28617

Query: 1115  VRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMT---------- 1164
             V+A N AG  +P +    V+ +      ++    D  G+ +    C   +          
Sbjct: 28618 VKAKNDAGYSEPREAFSSVIIK----EPQIEPTADLTGITNQLITCKAGSPFTIDVPISG 28673

Query: 1165  -PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGI 1218
              P  + +W  + +  +++ R+ + +  ++T +T KD    D G Y   + +T G+
Sbjct: 28674 RPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGV 28728



 Score =  209 bits (533), Expect = 1e-53
 Identities = 206/802 (25%), Positives = 328/802 (40%), Gaps = 99/802 (12%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVR--MGEYYEQYSAY 496
             P I+WY++   L  +  V    + + A++     ++ + G Y +++R  MG      SA 
Sbjct: 26902 PTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMG------SAS 26955

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
               +R    +  G P  P++ K + A K  I + W+ PA DGG+ I  Y ++K E     W
Sbjct: 26956 ATIRVQILDKPGPPGGPIEFKTVTAEK--ITLLWRPPADDGGAKITHYIVEKRETSRVVW 27013

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             S  ++  ++      T +I+G  YIFRVRAVNK GIG P      VA             
Sbjct: 27014 SMVSE-HLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVA------------- 27059

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
                             +  + PGPP    VT+ T++ + + W  P   G   I  YF+EK
Sbjct: 27060 ---------------KNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEK 27104

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              +  +  W +V  E  ++  R  +  L E   Y +RV   N+AG G  SE +E     D 
Sbjct: 27105 RDKKSLGWFKVLKE-TIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADP 27163

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCN-NNPVK 792
             +D P  P KI  + +T +S+ + W +        + GY +E       +W   +    V+
Sbjct: 27164 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 27223

Query: 793   GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPG 852
              + +    L  G +Y FRV AVN AG  E  + +E ++ K  +    +P++   ++    
Sbjct: 27224 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDIL---EAPEIDLDVALRTS 27280

Query: 853   GLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQ 912
              +  +   V    P         G  P   +     +NLG      +  T    L   PQ
Sbjct: 27281 VIAKAGEDVQVLIP-------FKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQ 27333

Query: 913   KAAPQ------------GKSKSDPLKKKTDRAPPSPPCD-ITCLESFRDSMVLGWKQPDK 959
                              G+ KS  +  K    P +  C  +      R ++ L W  P  
Sbjct: 27334 VTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAA--CQKLQVKHVSRGTVTLLWDPPLI 27391

Query: 960   IGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GG+ I  Y +  R   D     W   + K  S  ++K+ +L E   + F+V A N  G+
Sbjct: 27392 DGGSPIINYVIEKR---DATKRTWSVVSHKC-SSTSFKLIDLSEKTPFFFRVLAENEIGI 27447

Query: 1020  GAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
             G P   +E  K  E    VP P   L   +  K S++L W  P   G + +T Y V   E
Sbjct: 27448 GEPCETTEPVKAAE----VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---E 27500

Query: 1080  AKAKEDQ-WRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR 1138
              K K +Q W   +    K   ++V  LKE     FRV A N+ G+  P  + GP+  +  
Sbjct: 27501 RKGKGEQTWS--HAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI-GPITVKEL 27557

Query: 1139  -----------PGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVE 1187
                        PG  +V V +  +  + L +   K  PK   SW KD +  ++S  +   
Sbjct: 27558 IITPEVDLSDIPGA-QVTVRIGHNVHLELPY---KGKPKPSISWLKDGLPLKESEFVRFS 27613

Query: 1188  SKGNKTKMTFKDLGMDDLGIYS 1209
                NK  ++ K+   +  G Y+
Sbjct: 27614 KTENKITLSIKNAKKEHGGKYT 27635



 Score =  206 bits (525), Expect = 1e-52
 Identities = 199/815 (24%), Positives = 338/815 (41%), Gaps = 110/815 (13%)

Query: 438   QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
             +PE++W +    L+    ++   +     L   ++ + D G Y + +      +  +A+V
Sbjct: 25136 EPEVKWEKAEGILTDRAQIEV--TSSFTMLVIDNVTRFDSGRYNLTLENNSGSK--TAFV 25191

Query: 498   FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
              VR  D+     P+AP+++   E  KD + +SW+ P +DGG+ I  Y ++K E    +++
Sbjct: 25192 NVRVLDS-----PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 25246

Query: 558   QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRP 617
                +   K   F +  L EG SY FRV A N+ GIG P+  +EPV   +P          
Sbjct: 25247 TITNNCTK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP---------- 25295

Query: 618   SAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKC 676
                                 P PP  +++ + TR+   + W+ P   G   I  Y VE  
Sbjct: 25296 --------------------PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQ 25335

Query: 677   EAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
               G+E W   +T   VK+    +  L  G+ Y FRV   N  G  +P +   V V+   +
Sbjct: 25336 TKGSEKW---STCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG-VPVIARDI 25391

Query: 737   DIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRF 796
             +I   P   +P     T  V + E+ K     +    +     +  W        + +R 
Sbjct: 25392 EIK--PSVELPFH---TFNVKAREQLK-----IDVPFKGRPQATVNWRKDGQTLKETTRV 25441

Query: 797   TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTA 856
                   T  S   +  +    G  E    + A        G ++  +   + D PG    
Sbjct: 25442 NVSSSKTVTSLSIKEASKEDVGTYELCVSNSA--------GSITVPITIIVLDRPG--PP 25491

Query: 857   SRGRVHEAS---------PPTFQKDALLGSKPNKPSLPSS------SQNLGQTEVSKVSE 901
                R+ E S         PP +     + +   +    +S      SQ + +T +  V  
Sbjct: 25492 GPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRL 25551

Query: 902   TVQEELTPPPQKAAPQGKS---KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPD 958
             T   E           GKS   +S  +  +   +PP PP     + + + +M++ W+ P 
Sbjct: 25552 TTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPV 25611

Query: 959   KIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAG 1018
               GG+ + GY++ Y+E    +   W +AN   +++   K+S L E ++Y+++V A N+AG
Sbjct: 25612 NDGGSRVIGYHLEYKERSSIL---WSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAG 25668

Query: 1019  LGAPSAVSECFKCEEWTIAVPG-----PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGY 1073
             +G         KC +    VP      PP   + + + + S+ L+W  P + G   +TGY
Sbjct: 25669 IG---------KCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGY 25719

Query: 1074  FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA-GVGKPSDLAGP 1132
              V+ +E    + +W   N   I+  Y +V  L E   Y FRV A N A  V +PS+  GP
Sbjct: 25720 IVERRELP--DGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGP 25777

Query: 1133  VVAETRPGTKEVVVNVDDDGVISLNF-ECDKMT------PKSEFSWSKDYVSTEDSPRLE 1185
             ++ +       V+++V    VI +   E  K+       P    SW+KD +  E+  R E
Sbjct: 25778 IIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTE 25837

Query: 1186  VESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
             + S  N T +T KD    D G Y   + +  G  S
Sbjct: 25838 IISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRS 25872



 Score =  206 bits (523), Expect = 2e-52
 Identities = 199/804 (24%), Positives = 355/804 (44%), Gaps = 75/804 (9%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P  +W  +G  +   +          + LT  +  + D G Y I V      +  + ++ 
Sbjct: 17540 PTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 17599

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V D    + G P  P+++  L+   +++ ISW+ P  DGGSP++ Y ++K +   D+W  
Sbjct: 17600 VLD----VPGPPTGPINI--LDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 17653

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              +    K  +  +  L +G  Y+FRVRA NK+G+G P   +  V        A+ K  P 
Sbjct: 17654 VSSGSSK-TKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTV--------AKHKFSPP 17704

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
             +P                 PG P    VT+ T +   +SW  P   G   I  Y++E+ E
Sbjct: 17705 SP-----------------PGKPV---VTDITENAATVSWTLPKSDGGSPITGYYMERRE 17744

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
               T  W RVN + P+   +F +  L EG +Y FRV   N AG+ +PS +++       + 
Sbjct: 17745 V-TGKWVRVN-KTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK 17802

Query: 738   IPKAP-GKIIPSRNTDTSVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNP-VKG 793
              P  P    +  ++ +T+ +V W +  S     ++GY +E    G+ +W   N +  ++ 
Sbjct: 17803 PPGPPINPKLKDKSRETADLV-WTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 17861

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAI-GGGVSPDVC--PALSDE 850
               F   GL+ G  Y FR++A N  G  E  + +E++  K  +    V  DV     ++  
Sbjct: 17862 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVR 17921

Query: 851   PGGLTASRGRVHEASPP--TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELT 908
              G       RV     P  T+ K+  +  +  +  L    Q+L + E+ ++ E V+ +  
Sbjct: 17922 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL---IQDLPRVEL-QIKEAVRADHG 17977

Query: 909   PPPQKAA-PQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                  A    G ++   +    DR  P P  ++      +++  + W+ P   GG+EIT 
Sbjct: 17978 KYIISAKNSSGHAQGSAIVNVLDR--PGPCQNLKVTNVTKENCTISWENPLDNGGSEITN 18035

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             + V YR+     P +   + V +   +    +NL  N  Y F+V A N  G+G P+  ++
Sbjct: 18036 FIVEYRK-----PNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETK 18089

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW 1087
                     I  PG P +L  ++  K  + L+W+ P + G +P   Y V+ +  K  +D W
Sbjct: 18090 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVE-RRLKGSDD-W 18147

Query: 1088  RGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVN 1147
               +++ +IK  +  V    E   Y FRV+  N+ G    SD         +   ++ V++
Sbjct: 18148 ERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGG---ESDWVKTEEVVVKEDLQKPVLD 18204

Query: 1148  VDDDGVI------SLNFECD-KMTPKSEFSWSKDYVSTE--DSPRLEVESKGNKTKMTFK 1198
             +   GV+      ++  E   +  P  E +W+KD  +T+   SPR++++++ + +K +  
Sbjct: 18205 LKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT 18264

Query: 1199  DLGMDDLGIYSCDVTDTDGIASSY 1222
                  D G Y    T+T G   +Y
Sbjct: 18265 KAKRSDGGKYVVTATNTAGSFVAY 18288



 Score =  204 bits (519), Expect = 6e-52
 Identities = 197/777 (25%), Positives = 323/777 (41%), Gaps = 98/777 (12%)

Query: 474   KEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQP 533
             + D GLY I+V       +    V V D        P  P++    +  K  ++  W+ P
Sbjct: 14773 RPDHGLYMIKVENDHGIAKAPCTVSVLDT-------PGPPINFVFEDIRKTSVLCKWEPP 14825

Query: 534   AVDGGSPILGYFIDKCE-VGTDS-WSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMG 591
               DGGS I+ Y ++K +    DS W     T ++  ++ VT LIEG+ Y+FRVRA N+ G
Sbjct: 14826 LDDGGSEIINYTLEKKDKTKPDSEWIVVTST-LRHCKYSVTKLIEGKEYLFRVRAENRFG 14884

Query: 592   IGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATR 651
              G P  VS+P+ A DP                              P  P    V + T 
Sbjct: 14885 PG-PPCVSKPLVAKDPFGP---------------------------PDAPDKPIVEDVTS 14916

Query: 652   SYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFR 711
             + +++ W  P   G   + Y++EK E  + +W RVN  L + + +  +  L EG +Y FR
Sbjct: 14917 NSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVDGLLEGLTYVFR 14975

Query: 712   VRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTS---VVVSWEES--KDAK 766
             V   N+AG G+ S  ++     D +  P  P   IP R TDTS   + + WE        
Sbjct: 14976 VCAENAAGPGKFSPPSDPKTAHDPISPPGPP---IP-RVTDTSSTTIELEWEPPAFNGGG 15031

Query: 767   ELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDS 826
             E+VGY+++  + G+ +W  C    +K  ++T   +  G  Y  RV AVNAAG     +  
Sbjct: 15032 EIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQ 15091

Query: 827   EAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPS 886
                  +      V  DV        GG+    G+       T +  A++  +P    + +
Sbjct: 15092 PVTVAEPQEPPAVELDV-----SVKGGIQIMAGK-------TLRIPAVVTGRPVPTKVWT 15139

Query: 887   SSQ-----------NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPS 935
               +           N+G      + + ++++       A     SK    + +     P 
Sbjct: 15140 KEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV-PG 15198

Query: 936   PPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEA 995
             P  D+  + + R   +L W  P+  GG+EITG+ +  +   D     WR+     +  E 
Sbjct: 15199 PVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERK---DAKMHTWRQ----PIETER 15251

Query: 996   YK--ISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
              K  I+ L E   Y+F+V A N  G G P  +      +   +  P  P  L  +E  K 
Sbjct: 15252 SKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVD--PLGPPTSPERLTYTERTKS 15309

Query: 1054  SLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVF 1113
             ++ L WK P  +G +P+ GY ++ K    K D +  +N+         V  L E   Y F
Sbjct: 15310 TITLDWKEPRSNGGSPIQGYIIE-KRRHDKPD-FERVNKRLCPTTSFLVENLDEHQMYEF 15367

Query: 1114  RVRAINQAGVGKPSDLAGPVVAETR-PGTKEVVVNVDDDGV-----ISLNFECDKM-TPK 1166
             RV+A+N+ G  +PS     V+ +   P T ++ ++V  D +       ++   D    P 
Sbjct: 15368 RVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM 15427

Query: 1167  SEFSWSKDYVSTE------DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
              +  WSK+    E         + EV     KT+++      +D G Y+   ++  G
Sbjct: 15428 PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 15484



 Score =  202 bits (515), Expect = 2e-51
 Identities = 243/1051 (23%), Positives = 411/1051 (39%), Gaps = 156/1051 (14%)

Query: 274   LHAPEFIIKP-RSHTVWEK--ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIES 330
             L  PE  +K   SHTV+ +   N+K+   I+G P P+VT  ++ VP+         I   
Sbjct: 26471 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 26530

Query: 331   RYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
                  T+ +      D  +Y  +A N  G   A+ ++VV              G  T P+
Sbjct: 26531 NL---TINLKESVTADAGRYEITAANSSGTTKAFINIVVLD----------RPGPPTGPV 26577

Query: 391   SFG-VTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVP 449
                 +T      ++E     K+D            G +V     +K              
Sbjct: 26578 VISDITEESVTLKWE---PPKYDG-----------GSQVTNYILLKR------------E 26611

Query: 450   LSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIE 507
              S + W +   +  R  +    L   +E  + I+   R G      SA V V+       
Sbjct: 26612 TSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVK-LPYTTP 26670

Query: 508   GAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFA 567
             G P+ P         ++ I + W +P  +GGS ++GY ++  +  +  W + N   ++  
Sbjct: 26671 GPPSTPW---VTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTT 26727

Query: 568   RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIV 627
              F VT +  G  Y FRV A N  G+G PS  SEPV A+D  E                  
Sbjct: 26728 HFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACE------------------ 26769

Query: 628   TEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRV 686
                         PP ++ +T+ +++ V LSW+ P   G   I  Y VE+ +     W + 
Sbjct: 26770 ------------PPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKA 26817

Query: 687   NTELPVKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKI 745
             +    V   +F +  L +   Y FRV   N+ G +  PSE     VVG    I    G +
Sbjct: 26818 SFT-NVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSE-----VVGPITCIDSYGGPV 26871

Query: 746   IPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQ 805
             I      T VV         K   G  ++     SGK  P             + LV  +
Sbjct: 26872 IDLPLEYTEVV---------KYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE 26922

Query: 806   SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEAS 865
             +    + ++        +     ++++ A+G   S  +   + D+PG      G   E  
Sbjct: 26923 NTT-DLASILIKDADRLNSGCYELKLRNAMGSA-SATIRVQILDKPG----PPGGPIEFK 26976

Query: 866   PPTFQKDALLGSKPNKPSLPS------SSQNLGQTEVSKVSETVQEELTPPPQ------- 912
               T +K  LL   P               +   +   S VSE ++E +    +       
Sbjct: 26977 TVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEY 27036

Query: 913   --------KAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
                     K       +SD +  K     P PP      +  ++SM + W +P   GG++
Sbjct: 27037 IFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSD 27096

Query: 965   ITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSA 1024
             I+GY++  R   D     W +   + + +   K++ L EN  YQ++V A+N AG G  S 
Sbjct: 27097 ISGYFLEKR---DKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSE 27153

Query: 1025  VSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE 1084
              SE +K  +  I  PGPP  ++ ++  K S+ L W  PV+ G + VTGY V++++   +E
Sbjct: 27154 PSEFYKAAD-PIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ--GEE 27210

Query: 1085  DQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKE 1143
             ++W  ++ +  ++     V  LK GV+Y FRV A+N AG G+P ++  PV A+      E
Sbjct: 27211 EEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE 27270

Query: 1144  ----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKT 1193
                       V+    +D  + + F   K  P    +W KD  +     R  +E+  + +
Sbjct: 27271 IDLDVALRTSVIAKAGEDVQVLIPF---KGRPPPTVTWRKDEKNLGSDARYSIENTDSSS 27327

Query: 1194  KMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVE 1253
              +T   +  +D G Y   + +  G   S  +  + L             T     +L V+
Sbjct: 27328 LLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVL------------DTPAACQKLQVK 27375

Query: 1254  ILEKGQVRFWMQAEKLSGNAK-VNYIFNEKE 1283
              + +G V        + G +  +NY+  +++
Sbjct: 27376 HVSRGTVTLLWDPPLIDGGSPIINYVIEKRD 27406



 Score =  202 bits (513), Expect = 3e-51
 Identities = 201/738 (27%), Positives = 302/738 (40%), Gaps = 66/738 (8%)

Query: 438   QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
             +P I W ++G+PL  S++V+   +  + TL+  +  KE  G YT+ +            V
Sbjct: 27592 KPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 27651

Query: 498   FVRDADAEIEGAPAAPLD-VKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
                       G P+ P   ++  E   D +I+SW  P  +GG  I  Y I+K E    +W
Sbjct: 27652 ITL-------GPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 27704

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
                  +  +   F V  L++   Y FRVRA N+ G+                        
Sbjct: 27705 KMVCSSVAR-TTFKVPNLVKDAEYQFRVRAENRYGV------------------------ 27739

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYF-VEK 675
              S P    IIV + +     +PGPP    +   T   + L+W  P   G   +  F VEK
Sbjct: 27740 -SQPLVSSIIVAKHQFR---IPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEK 27795

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  WQ+VNT  P+    +    L EG  Y FRV   NSAG+  PS+ ++ T+    
Sbjct: 27796 KERNSILWQKVNTS-PISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSP 27854

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKG 793
             +D P  P  I  +R T   + + W         ++VGY IE    G+ +W  CN   V  
Sbjct: 27855 VDPPGTPDYIDVTRET---ITLKWNPPLRDGGSKIVGYSIEKR-QGNERWVRCNFTDVSE 27910

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAIGGGV---SPDVCPALSD 849
              ++T  GL  G  Y FR+ A NA G +S  SQ S  I  +      +    P+    L  
Sbjct: 27911 CQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLII 27970

Query: 850   EPGGLTASRGRVHEASPP--TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEEL 907
             + G     +  V     P  T+ KD   G +  K      +  LG T +     T     
Sbjct: 27971 KSGESLRIKALVQGRPVPRVTWFKD---GVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 28027

Query: 908   TPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                 +     G +K++ +K K    P      I       + M L W  P   G A IT 
Sbjct: 28028 VYTVEAKNASGSAKAE-IKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITH 28086

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             Y +  RE    +     E   +A S  A K+ N  E   YQF+V+A+N  G+G P     
Sbjct: 28087 YIIEKRET-SRLAWALIEDKCEAQSYTAIKLINGNE---YQFRVSAVNKFGVGRPLDSDP 28142

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW 1087
                  ++T  VP  P   + S +  +S+ L W  P   G + +  Y ++ +E K+   +W
Sbjct: 28143 VVAQIQYT--VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS--TRW 28198

Query: 1088  -RGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE--TRPGTKEV 1144
              + +++  I     KV GL EG  Y F V A N AGVG  S ++  +       P     
Sbjct: 28199 VKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPT 28258

Query: 1145  VVNVDDDGVISLNFECDK 1162
             VV V D    +++ E  K
Sbjct: 28259 VVKVTDTSKTTVSLEWSK 28276



 Score =  201 bits (510), Expect = 6e-51
 Identities = 194/718 (27%), Positives = 295/718 (41%), Gaps = 94/718 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P++ W    + L  +  V    + +R TLT     + D G Y + +      + +S  V 
Sbjct: 28677 PKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVV 28736

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V      + G    P++V  + A     ++SW +P   GG+ I  Y ++K E GT +W  
Sbjct: 28737 VIGRPGPVTG----PIEVSSVSAES--CVLSWGEPKDGGGTEITNYIVEKRESGTTAWQL 28790

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              N + VK  +  VT L +   Y FRV + N+ G+  P   S P+ A  P           
Sbjct: 28791 VNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE-SAPIIAEHPF---------- 28838

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                              + P  PT   V   + + + + W+ P   G   I+ Y+VEK E
Sbjct: 28839 -----------------VPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKE 28881

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
               T  W + N ++P     + +  L EG  Y FR    N+AGV + SEA+   +  + +D
Sbjct: 28882 RNTILWVKEN-KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVD 28940

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIE---ASVAGSGKWEPCNNNPVKGS 794
              P  P     +R+T  S++ S        ++VGY IE    S  G G+W  CN   V  +
Sbjct: 28941 APGRPEVTDVTRST-VSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDN 28999

Query: 795   RFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG 853
              FT   L  G +Y FRV A NAAG +S+ S+ +  +  +         +  P  ++    
Sbjct: 29000 FFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR--------DEYAPPKAELDAR 29051

Query: 854   LTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQK 913
             L      +   S      DA +G KP     P      G  E+  + E V  + T     
Sbjct: 29052 LHGDLVTIRAGSDLVL--DAAVGGKPE----PKIIWTKGDKELD-LCEKVSLQYTGKRAT 29104

Query: 914   AAPQGKSKSDPLK------------------KKTDRAPPSPPCDITCLESFRDSMVLGWK 955
             A  +   +SD  K                  K  D   P P   +T     ++   L W 
Sbjct: 29105 AVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLD--SPGPCGKLTVSRVTQEKCTLAWS 29162

Query: 956   QPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEE----AYKISNLKENMVYQFQV 1011
              P + GGAEIT Y V  RE            N   V  E    +Y ++ L +N  Y F+V
Sbjct: 29163 LPQEDGGAEITHYIVERRET--------SRLNWVIVEGECPTLSYVVTRLIKNNEYIFRV 29214

Query: 1012  AAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVT 1071
              A+N  G G P           +TI  P PP   +     K+ +++QW  P   G   ++
Sbjct: 29215 RAVNKYGPGVPVESEPIVARNSFTI--PSPPGIPEEVGTGKEHIIIQWTKPESDGGNEIS 29272

Query: 1072  GYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              Y VD +E K+   +W  +N +  + +  LKV  L EG  Y FRV A+N AG  +PS+
Sbjct: 29273 NYLVDKREKKSL--RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 29328



 Score =  191 bits (486), Expect = 4e-48
 Identities = 191/741 (25%), Positives = 302/741 (40%), Gaps = 88/741 (11%)

Query: 412   DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH 471
             DV   R G+T+ +  RV   PE     P+I W + G  L   K V  +    R  L    
Sbjct: 17916 DVITVRVGQTIRILARVKGRPE-----PDITWTKEGKVLVREKRVDLIQDLPRVELQIKE 17970

Query: 472   LNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWK 531
               + D G Y I  +    + Q SA V V D        P    ++K     K+   ISW+
Sbjct: 17971 AVRADHGKYIISAKNSSGHAQGSAIVNVLDR-------PGPCQNLKVTNVTKENCTISWE 18023

Query: 532   QPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMG 591
              P  +GGS I  + ++  +     WS       K  R     L+    Y FRV A NK+G
Sbjct: 18024 NPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTK--RLIKANLLANNEYYFRVCAENKVG 18081

Query: 592   IGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATR 651
             +G       P+ A++P ++                           PG P +L + +  +
Sbjct: 18082 VGPTIETKTPILAINPIDR---------------------------PGEPENLHIADKGK 18114

Query: 652   SYVVLSWKPPG-QRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCF 710
             ++V L W+ P    G   + Y VE+   G+++W+RV+ +  +K   + +    E + Y F
Sbjct: 18115 TFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVH-KGSIKETHYMVDRCVENQIYEF 18173

Query: 711   RVRCSNSAGVGEPSEATEVTVVGD----KLDIPKAPGKIIPSRNT---DTSV------VV 757
             RV+  N  G  +  +  EV V  D     LD+  +    + + +T   +  V       V
Sbjct: 18174 RVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEV 18233

Query: 758   SWEESKDAKELV---GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             +W + KDA +L       I+   A S K+         G ++      T  S++     V
Sbjct: 18234 AWTKDKDATDLTRSPRVKIDTR-ADSSKFSLTKAKRSDGGKYVVTATNTAGSFV-AYATV 18291

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEP--GGLTASRGRVHEASPPTFQKD 872
             N        ++ + ++        VS D C    D P   G    +  + E         
Sbjct: 18292 NVLDKPGPVRNLKIVD--------VSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW 18343

Query: 873   ALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRA 932
             +   +    P    +    G   + +V    +    PP +      K+K D    K  R 
Sbjct: 18344 STYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYD----KPGR- 18398

Query: 933   PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVS 992
              P PP ++T +   ++ M + W  P+  GG  ITGY++  +E       +W   N  A+ 
Sbjct: 18399 -PDPP-EVTKVS--KEEMTVVWNPPEYDGGKSITGYFLEKKEKHS---TRWVPVNKSAIP 18451

Query: 993   EEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRK 1052
             E   K+ NL  +  YQF+V A N  G+G PS  S     ++  I  PGPP + +  +  K
Sbjct: 18452 ERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKD-PIEPPGPPTNFRVVDTTK 18510

Query: 1053  DSLVLQWKPPVHSGRTPVTGYFVDL--KEAKAKEDQ-WRGLNEAA-IKNVYLKVRGLKEG 1108
              S+ L W  PV+ G  P+ GY V++  K A A  D+ W+  N AA +      V  L E 
Sbjct: 18511 HSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDEN 18570

Query: 1109  VSYVFRVRAINQAGVGKPSDL 1129
               Y FRV A NQ G+G+P++L
Sbjct: 18571 QEYEFRVCAQNQVGIGRPAEL 18591



 Score =  191 bits (484), Expect = 7e-48
 Identities = 185/740 (25%), Positives = 303/740 (40%), Gaps = 88/740 (11%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P+ P +V  L+  K  + +SW +P  DGGS + GY+I++ E  TD W + N T +    +
Sbjct: 30332 PSNPPEV--LDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMY 30389

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGL+    Y FR+ A N +G+   S  SEPV   DP +K                   
Sbjct: 30390 TVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDK------------------- 30430

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNT 688
                     P  P +L +   ++  V L W KP    G E + Y+VE  ++G   W++ N 
Sbjct: 30431 --------PSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNK 30482

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPS 748
             E  +K  +F +  L E   Y FRV   N  G+  P        +  KL   +APG     
Sbjct: 30483 ER-IKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTKLTSGEAPGIRKEM 30539

Query: 749   RNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYI 808
             ++  T +    E ++ + ++VG  +        KW       ++  ++       G+++ 
Sbjct: 30540 KDVTTKL---GEAAQLSCQIVGRPLPDI-----KWYRFGKELIQSRKYKMSS--DGRTHT 30589

Query: 809   FRVRAVNAAGLSEYS----QDSEAIEVKAAIGGGVSPDVCPA--LSDEPGGLTASRGRVH 862
               V          Y+     +   +E  + +    +P   P   L ++  G   S  R+H
Sbjct: 30590 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLH 30649

Query: 863   EA--SPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS 920
                   P        G K     L  +S+N+        +  V + +    Q+    GK 
Sbjct: 30650 VMYIGRPVPAMTWFHGQK-----LLQNSENITIENTEHYTHLVMKNV----QRKTHAGKY 30700

Query: 921   KSDP----------LKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYV 970
             K             L  +    P  P   I      ++S V+ WK P   GG+ IT Y V
Sbjct: 30701 KVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVV 30760

Query: 971   NYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK 1030
                E  +G   +W+  +  A+S    +I NL EN  Y F+V+A N  G+  P  VS    
Sbjct: 30761 EKCEAKEGA--EWQLVS-SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVI 30817

Query: 1031  CEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGL 1090
              +      PG P     + V KDS V+ WKPP   G   +  Y+++ +E   K+++W  +
Sbjct: 30818 IKS-PFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKRE--KKQNKWISV 30874

Query: 1091  NEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET-----RPGTKEVV 1145
                 I+     V+ L EG+ Y FRV+  N  G  + S+++ P+  ++      P  KE +
Sbjct: 30875 TTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEEL 30934

Query: 1146  VNVDDDGVISLNFECDKMT--PKSEFSW---SKDYVSTEDSPRLEVESKGNKTKMTFKDL 1200
              N++     +    C K+T  PK    W    K+ ++     R++ E KG   ++    +
Sbjct: 30935 RNLNVRYQSNATLVC-KVTGHPKPIVKWYRQGKEIIADGLKYRIQ-EFKGGYHQLIIASV 30992

Query: 1201  GMDDLGIYSCDVTDTDGIAS 1220
               DD  +Y    T+  G  S
Sbjct: 30993 TDDDATVYQVRATNQGGSVS 31012



 Score =  189 bits (481), Expect = 1e-47
 Identities = 201/817 (24%), Positives = 331/817 (40%), Gaps = 114/817 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             PEI W R     +    VQ         L+  + ++ D G Y +++      +  SA+V 
Sbjct: 24054 PEITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSK--SAFVT 24109

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V+  D      P  P ++   E  KD   + W+ P +DGG+ +  Y IDK E    +++ 
Sbjct: 24110 VKVLDT-----PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYAN 24164

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              +    K + F V  L EG  Y FRV A N+ G+G P    + V A +P           
Sbjct: 24165 VSSKCSKTS-FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP----------- 24212

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                                P PP  +++T+ +++   L W+ P   G   ++ Y VE   
Sbjct: 24213 -------------------PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 24253

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
              GTE W  V      K     +  L+ G+ Y FRV+  N  G  +P     V V+   L 
Sbjct: 24254 KGTEKWSIVAES---KVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP-RVLGVPVIAKDLT 24309

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGK----WEPCNNNPVKG 793
             I   P   +P          S +  +D K      IE  V G  +    W   +  P+K 
Sbjct: 24310 IQ--PSLKLPFNT------YSIQAGEDLK------IEIPVIGRPRPNISWVK-DGEPLKQ 24354

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG 853
             +    +   T  S +  ++  N     +Y+       V A    G + +    +  E  G
Sbjct: 24355 TT-RVNVEETATSTVLHIKEGNKDDFGKYT-------VTATNSAGTATENLSVIVLEKPG 24406

Query: 854   LTASRGRVHEAS---------PPTFQKDALLGSK-PNKPSLPSSSQNLGQTEVSKVSETV 903
                   R  E S         PP +     + +    K    +++ ++    V++ +  +
Sbjct: 24407 PPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKI 24466

Query: 904   QEELTPPPQKA---APQGKSKSDPLKKKT-----DRAPPSPPCDITCLESFRDSMVLGWK 955
              +  T    +    A     KS PL  K          P PP         +D M++ W 
Sbjct: 24467 TKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWH 24526

Query: 956   QPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMN 1015
             +P   GG +I GY++  +E    +   W + N   + +  +K + L E + Y+F+V+A N
Sbjct: 24527 EPVNDGGTKIIGYHLEQKEKNSIL---WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAEN 24583

Query: 1016  MAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFV 1075
             + G+G PS VSECF   +     PG P ++    + ++++ L+WK P + G + +TGY V
Sbjct: 24584 IVGIGKPSKVSECFVARD-PCDPPGRPEAI---VITRNNVTLKWKKPAYDGGSKITGYIV 24639

Query: 1076  DLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAG-VGKPSDLAGPVV 1134
             + K+    + +W   +   +      V GL E   Y FRV A N AG   +PSD +G + 
Sbjct: 24640 EKKD--LPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAIT 24697

Query: 1135  AETR---------PGTKEV-VVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTED-SPR 1183
             A            P  K+V VV+  +  V+  +    +  P  +  WSKD    E+ + R
Sbjct: 24698 ARDEIDAPNASLDPKYKDVIVVHAGETFVLEADI---RGKPIPDVVWSKDGKELEETAAR 24754

Query: 1184  LEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
             +E++S   KT +  KD    D G Y   +++  G  S
Sbjct: 24755 MEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 24791



 Score =  188 bits (477), Expect = 4e-47
 Identities = 155/528 (29%), Positives = 237/528 (44%), Gaps = 49/528 (9%)

Query: 638   PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
             P PP +L VTE T+  V ++W+PP   G   I  Y VEK EA  +++  V T     S  
Sbjct: 23034 PSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNS-- 23091

Query: 697   FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
             + +  L EG SY FRV   N  G+G P++  +   V +   +P+ PGKI     T  SV 
Sbjct: 23092 WKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE---VPQPPGKITVDDVTRNSVS 23148

Query: 757   VSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             +SW   E     +++ Y +E     S KW  C    VK  +     L  G+ Y+FRV AV
Sbjct: 23149 LSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEYLFRVVAV 23206

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDAL 874
             N  G S+    +  I  K  +   + PDV PA S      +   G+  +   P       
Sbjct: 23207 NEKGRSDPRSLAVPIVAKDLV---IEPDVKPAFSS----YSVQVGQDLKIEVP------- 23252

Query: 875   LGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-------------K 921
             +  +P KP++  +   L   + ++++ T   +LT    K   +                K
Sbjct: 23253 ISGRP-KPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQK 23311

Query: 922   SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPG 981
             +  ++  T   P  P   +   +   +S+ L W  P   GG +IT Y V  R+    V  
Sbjct: 23312 TASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTV-- 23369

Query: 982   KWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGP 1041
              W   +   V+    K++ LK    YQF++ A N    G   A+       ++    PGP
Sbjct: 23370 -WDVVSA-TVARTTLKVTKLKTGTEYQFRIFAENR--YGQSFALESDPIVAQYPYKEPGP 23425

Query: 1042  PHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLK 1101
             P +   + + KDS+V+QW  PV++G +PV GY ++ KE  +    W  +N+  I +   K
Sbjct: 23426 PGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNS--ILWTKVNKTIIHDTQFK 23483

Query: 1102  VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVV 1146
              + L+EG+ Y FRV A N  GVGK S  +   VA      PGT E ++
Sbjct: 23484 AQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIM 23531



 Score =  179 bits (455), Expect = 2e-44
 Identities = 211/823 (25%), Positives = 315/823 (38%), Gaps = 119/823 (14%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRV--RMGEYYEQYSAY 496
             P++ W + G+     K    L     A L   +  ++D G Y++ +    GE     + +
Sbjct: 18636 PKVTWRKVGIDNVVRKGQVDLVD-TMAFLVIPNSTRDDSGKYSLTLVNPAGEK----AVF 18690

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             V VR  D      P    D+K  +  K    +SW  P  DGGS +  Y ++K E    +W
Sbjct: 18691 VNVRVLDT-----PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW 18745

Query: 557   SQCNDTP-VKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKS 615
             S    TP VK   F VT L+ G  Y FRV AVN+ G G P+ V +PV A DP  +     
Sbjct: 18746 STV--TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE----- 18798

Query: 616   RPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEK 675
                                   P PP  L VTE T++   L+W PP + G   I  ++  
Sbjct: 18799 ----------------------PDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITS 18836

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
                  +   R      VK     +  L EGK Y FRV   N+ GV  P EA  V    ++
Sbjct: 18837 YREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQ 18896

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSG----KWEPCNNNPV 791
             L  PK    ++P + T           K  K+L    IEA V G      KW+   +  V
Sbjct: 18897 LLPPKI---LMPEQIT----------IKAGKKL---RIEAHVYGKPHPTCKWKKGEDEVV 18940

Query: 792   KGSRFTCHGLVTGQSYIFRVRAVNAAGL----SEYSQDSEAIEVKAAIGGGVSPDVCPA- 846
               S    H   +    I +      +G     +E S  ++  ++K  +     P   P  
Sbjct: 18941 TSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFD 19000

Query: 847   LSD--------------EPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLG 892
             +SD              E GG   +   V +           L S   K S        G
Sbjct: 19001 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASV-TKTSCRVGKLIPG 19059

Query: 893   QTEVSKVSET----VQEELTPPPQKAA-PQGKSKSDPLKKKTDRAPPSPPCDITCLESFR 947
             Q  + +V       + E LT P   A  P G               PS P +    +  +
Sbjct: 19060 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGV--------------PSEPKNARVTKVNK 19105

Query: 948   DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY 1007
             D + + W +PD  GG+ I GY +  +E    +   W +AN   V    Y  + L E + Y
Sbjct: 19106 DCIFVAWDRPDSDGGSPIIGYLIERKERNSLL---WVKANDTLVRSTEYPCAGLVEGLEY 19162

Query: 1008  QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 1067
              F++ A+N AG   PS  +E +      +  PG P  +   +V K ++ L W  P H G 
Sbjct: 19163 SFRIYALNKAGSSPPSKPTE-YVTARMPVDPPGKPEVI---DVTKSTVSLIWARPKHDGG 19218

Query: 1068  TPVTGYFVDLKEAKAKEDQWRGLNEAA--IKNVYLKVRGLKEGVSYVFRVRAINQAGVGK 1125
             + + GYFV+    K   D+W   N A   I        GL+E   Y FR  A     +  
Sbjct: 19219 SKIIGYFVEA--CKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISP 19276

Query: 1126  PSDLAGPV--VAETRPGTKEVVVNVDDDGVISLNFE-CDKMT----PKSEFSWSKDYVST 1178
             PS+ + PV  +AE  P   ++ V +     +      C   T    P    SW KD    
Sbjct: 19277 PSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLL 19336

Query: 1179  EDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
             + +  +++  + N   +    +   D G Y+    ++ G  S+
Sbjct: 19337 KPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSA 19379



 Score =  177 bits (450), Expect = 6e-44
 Identities = 186/778 (23%), Positives = 306/778 (39%), Gaps = 86/778 (11%)

Query: 465   ATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKD 524
             +TLT  + N+ D G YT+ V      +  +  V V D        P  P+  K  +  + 
Sbjct: 28411 STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPG-----PPGPITFK--DVTRG 28463

Query: 525   YIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRV 584
                + W  P +DGG+ I  Y ++K E    SW   ++   +   F V  L EG  Y FRV
Sbjct: 28464 SATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQI-FKVNDLAEGVPYYFRV 28522

Query: 585   RAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDL 644
              AVN+ G+G P  + EP+ A                       TE+       P PP  L
Sbjct: 28523 SAVNEYGVGEPYEMPEPIVA-----------------------TEQ-------PAPPRRL 28552

Query: 645   SVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLA 703
              V + ++S  VL+W  P   G   I  Y +E  + G++ W         K   F +  L 
Sbjct: 28553 DVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH---TKQLTFTVERLV 28609

Query: 704   EGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK-----LDIPKAPGKIIPSRNTDTSVVVS 758
             E   Y FRV+  N AG  EP EA    ++ +       D+     ++I  +      +  
Sbjct: 28610 EKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDV 28669

Query: 759   WEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAG 818
                 + A ++     E  +  + +           +  T    + G S  + +   N AG
Sbjct: 28670 PISGRPAPKVTWKLEEMRLKETDRVSITTTKD--RTTLTVKDSMRGDSGRYFLTLENTAG 28727

Query: 819   LSEYSQDSEAIEVKAAIGG-----GVSPDVCPALSDEP--GGLTASRGRVHEASPPTFQK 871
             +  +S     I     + G      VS + C     EP  GG T     + E        
Sbjct: 28728 VKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRE----- 28782

Query: 872   DALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-KSDPLKKKTD 930
                  S      L +SS    Q +V+ +++ ++       +      K  +S P+  +  
Sbjct: 28783 -----SGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHP 28837

Query: 931   RAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKA 990
               PPS P          ++M + W++P   GG++I GY+V  +E    +   W + N   
Sbjct: 28838 FVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTIL---WVKENKVP 28894

Query: 991   VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEV 1050
               E  YK++ L E + YQF+  A+N AG+   S  S     +   +  PG P   + ++V
Sbjct: 28895 CLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQN-PVDAPGRP---EVTDV 28950

Query: 1051  RKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKED-QWRGLNEAAIKNVYLKVRGLKEGV 1109
              + ++ L W  P + G + V GY ++ K      D +W   N   + + +  V  L EG 
Sbjct: 28951 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 29010

Query: 1110  SYVFRVRAINQAGV-GKPSDLAGPVVA--ETRPGTKEVVVNVDDDGVISLNFECDKM--- 1163
             +Y FRV A N AGV  K S+  GPV    E  P   E+   +  D ++++    D +   
Sbjct: 29011 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD-LVTIRAGSDLVLDA 29069

Query: 1164  ----TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
                  P+ +  W+K     +   ++ ++  G +     K     D G Y+  V +  G
Sbjct: 29070 AVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 29127



 Score =  167 bits (422), Expect = 1e-40
 Identities = 156/528 (29%), Positives = 237/528 (44%), Gaps = 54/528 (10%)

Query: 637   VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFV-EKCEAGTENWQRVNTELPVKSP 695
             VPGP  DL      R   +L+W  P   G   I  F+ E+ +A    W++     P+++ 
Sbjct: 15196 VPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ-----PIETE 15250

Query: 696   RFA--LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDT 753
             R    +  L EG+ Y FRV   N  G G P E   +  V D L  P +P ++  +  T +
Sbjct: 15251 RSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAV-DPLGPPTSPERLTYTERTKS 15309

Query: 754   SVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRV 811
             ++ + W+E  S     + GY IE        +E  N      + F    L   Q Y FRV
Sbjct: 15310 TITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRV 15369

Query: 812   RAVNAAGLSEYS-------QDSEA---IEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV 861
             +AVN  G SE S       QD E    I+++ ++ G    D     + EP  + A    V
Sbjct: 15370 KAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG----DTIKVKAGEPVHIPAD---V 15422

Query: 862   HEASPPTFQ--KDALLGSKPNKP---SLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAP 916
                  P  +  K+  +  KP      +    S++  +TE+S      +++ T     +  
Sbjct: 15423 TGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNR 15482

Query: 917   QGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVI 976
              G    +   +  DR  PSPP ++   +   +S  L W  P   GG+EIT Y ++ R+  
Sbjct: 15483 LGSVFRNVHVEVYDR--PSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDA- 15539

Query: 977   DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
                  +W E    AV E+ Y I  L  N  Y+F+V A+N  G+       EC K ++  I
Sbjct: 15540 SRKKAEWEEVTNTAV-EKRYGIWKLIPNGQYEFRVRAVNKYGIS-----DEC-KSDKVVI 15592

Query: 1037  A----VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNE 1092
                  +PGPP   K     K S+++ W PP+ +G +P+TGY+++ +E  +    W  ++ 
Sbjct: 15593 QDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSP--YWSRVSR 15650

Query: 1093  AAIKNVYLK-----VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA 1135
             A I  V LK     V  L EGV Y FR  AIN AG+G PS+ + P VA
Sbjct: 15651 APITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVA 15698



 Score =  157 bits (397), Expect = 8e-38
 Identities = 201/762 (26%), Positives = 300/762 (39%), Gaps = 125/762 (16%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESR-YGM------HTLEINGCDF 344
             E  +L C I G P P + WY+           GK +I+SR Y M      HTL +   + 
Sbjct: 30548 EAAQLSCQIVGRPLPDIKWYRF----------GKELIQSRKYKMSSDGRTHTLTVMTEEQ 30597

Query: 345   EDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFE 404
             ED   Y   A N  GE+   + ++++         +FH G    PL              
Sbjct: 30598 EDEGVYTCIATNEVGEVETSSKLLLQA------TPQFHPG---YPLK------------- 30635

Query: 405   IHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGER 464
                 +K+   +G  G T+ L    +  P      P + W+     L  S+ + T+ + E 
Sbjct: 30636 ----EKY---YGAVGSTLRLHVMYIGRPV-----PAMTWFHGQKLLQNSENI-TIENTEH 30682

Query: 465   AT-LTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDA--DAEIEGAPAAPLDVKCLEA 521
              T L   ++ +        +   G+Y  Q S      DA  D EI+  P  P     +EA
Sbjct: 30683 YTHLVMKNVQR--------KTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEA 30734

Query: 522   N-KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSY 580
               K+  +ISWK PA DGGS I  Y ++KCE    +  Q   + +      +  L E   Y
Sbjct: 30735 LLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGY 30794

Query: 581   IFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGP 640
              FRV A N  GI  P  VS  V    P EK                           PG 
Sbjct: 30795 YFRVSAQNTFGISDPLEVSSVVIIKSPFEK---------------------------PGA 30827

Query: 641   PTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFAL 699
             P   ++T  T+   V++WKPP   G   I  Y++EK E     W  V TE  ++   F++
Sbjct: 30828 PGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTE-EIRETVFSV 30886

Query: 700   FDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP-KAPGKIIPSRNTD----TS 754
              +L EG  Y FRV+C N  G  E SE +E   +  K D+P +AP      RN +    ++
Sbjct: 30887 KNLIEGLEYEFRVKCENLGGESEWSEISE--PITPKSDVPIQAPHFKEELRNLNVRYQSN 30944

Query: 755   VVVSWEESKDAKELVGYYIEAS--VAGSGKWEPCNNNPVKGS--RFTCHGLVTGQSYIFR 810
               +  + +   K +V +Y +    +A   K+        KG   +     +    + +++
Sbjct: 30945 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKY---RIQEFKGGYHQLIIASVTDDDATVYQ 31001

Query: 811   VRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQ 870
             VRA N  G S     S  +EV A I         P   +  G + A RG V     P   
Sbjct: 31002 VRATNQGG-SVSGTASLEVEVPAKIH-------LPKTLEGMGAVHALRGEVVSIKIPFSG 31053

Query: 871   K-DALLGSKPNKPSLPSSSQN---LGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLK 926
             K D ++  +  +  + ++      + ++  S V     E           + +   D   
Sbjct: 31054 KPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKT 31113

Query: 927   KKTDRAP-PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWRE 985
              + D A  P PP  +   +  RDS+ L W +P   GG++IT Y V   E       +W  
Sbjct: 31114 VELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV---EKCATTAERW-- 31168

Query: 986   ANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
               V    E  Y + NL     YQF+V A N  GL  PS  SE
Sbjct: 31169 LRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSE 31210



 Score =  153 bits (387), Expect = 1e-36
 Identities = 143/539 (26%), Positives = 230/539 (42%), Gaps = 61/539 (11%)

Query: 637   VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFV-EKCEAGTENWQRVNTELPVKSP 695
             +PGP  D+  ++ T+S   L+W+PP   G   I+++V E+ EAG        T +PV S 
Sbjct: 14479 LPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRR------TYIPVMSG 14532

Query: 696   R----FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNT 751
                  + + DL     Y FRV+  N  G GE  E     +  D    P  P  +     T
Sbjct: 14533 ENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPT 14592

Query: 752   DTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIF 809
               ++ ++W+        +++GY IE    G  +W+ CN + V    +T  GL  G+ Y F
Sbjct: 14593 AEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQF 14652

Query: 810   RVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVC--PALSDEPGGLTASRGRVHEASPP 867
             RVRA NAAG+SE    S A     A+    +P V    +L  + G   A    +  +  P
Sbjct: 14653 RVRAENAAGISE---PSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYP 14709

Query: 868   TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEE---LTPPPQKAAPQGKSKSDP 924
             T     +   K     +P   +      V +    VQEE   + P  Q+ +     K + 
Sbjct: 14710 T-----ITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 14764

Query: 925   ----------------LKKKTDRAPPSPPCDITCLES--------FRD----SMVLGWKQ 956
                             +K + D      PC ++ L++        F D    S++  W+ 
Sbjct: 14765 QLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEP 14824

Query: 957   PDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNM 1016
             P   GG+EI  Y +  ++     P          +    Y ++ L E   Y F+V A N 
Sbjct: 14825 PLDDGGSEIINYTLEKKDKTK--PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 14882

Query: 1017  AGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVD 1076
              G G P  VS+    ++     P  P      +V  +S++++W  P  +G +P+ GY+++
Sbjct: 14883 FGPG-PPCVSKPLVAKD-PFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNG-SPILGYWLE 14939

Query: 1077  LKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA 1135
              +E  +    W  +N++ +  +   V GL EG++YVFRV A N AG GK S  + P  A
Sbjct: 14940 KREVNS--THWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTA 14996



 Score =  153 bits (386), Expect = 2e-36
 Identities = 113/372 (30%), Positives = 180/372 (48%), Gaps = 30/372 (8%)

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
             +S P+       PP PP         +DSMV+ W +P   GG EI GY +  R+  +GV 
Sbjct: 24889 ESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDK-EGV- 24946

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
              +W + N K +++   +++ L E   Y+F+VAA N AG+G PS  S  ++  +  +  PG
Sbjct: 24947 -RWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD-ALYPPG 25004

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVY 1099
             PP + K ++  + S+ L W  P++ G  PV GY V++KEA A  D+W        ++   
Sbjct: 25005 PPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAA--DEWTTCTPPTGLQGKQ 25062

Query: 1100  LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN-- 1157
               V  LKE   Y FR+ AIN  GVG+P+ L G VVA+ R    E+ ++ D   V+ L   
Sbjct: 25063 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 25122

Query: 1158  -----FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
                  F   K  P+ E  W K      D  ++EV S  + T +   ++   D G Y+  +
Sbjct: 25123 ATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLVIDNVTRFDSGRYNLTL 25180

Query: 1213  TDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGN 1272
              +  G  ++++       R+L        P+ PV   L +  ++K  V    +   + G 
Sbjct: 25181 ENNSGSKTAFV-----NVRVL------DSPSAPV--NLTIREVKKDSVTLSWEPPLIDGG 25227

Query: 1273  AKV-NYIFNEKE 1283
             AK+ NYI  ++E
Sbjct: 25228 AKITNYIVEKRE 25239



 Score =  152 bits (385), Expect = 2e-36
 Identities = 165/617 (26%), Positives = 249/617 (40%), Gaps = 104/617 (16%)

Query: 478   GLYTIRVRMGEYY----EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQP 533
             G Y  RVR    Y    E  S  V ++D    + G P  P   K L   K  +++SW  P
Sbjct: 15567 GQYEFRVRAVNKYGISDECKSDKVVIQDP-YRLPGPPGKP---KVLARTKGSMLVSWTPP 15622

Query: 534   AVDGGSPILGYFIDKCEVGTDSWSQCNDTPV-----KFARFPVTGLIEGRSYIFRVRAVN 588
               +GGSPI GY+++K E G+  WS+ +  P+     K   F V  L+EG  Y FR  A+N
Sbjct: 15623 LDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 15682

Query: 589   KMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTE 648
               GIG PS  S+P  A DP                              PGPP+   V +
Sbjct: 15683 AAGIGPPSEPSDPEVAGDPI---------------------------FPPGPPSCPEVKD 15715

Query: 649   ATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT-ELPVKSPRFALFDLAEGK 706
              T+S + L WKPP + G   I  Y VE  E GT +W+RVN  +  + +    + +L E +
Sbjct: 15716 KTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELR 15775

Query: 707   SYCFRVRCSNSAGVGEPSEATE-----------------------VTVVGDKLDIPKAPG 743
              Y FRV+  N AG  EPS+ T                        V   G ++ IP    
Sbjct: 15776 KYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPA--- 15832

Query: 744   KIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVT 803
              +I  R T  S   SWE    AK+ +   +   +    + E   N+ V      C    T
Sbjct: 15833 -VIKGRPTPKS---SWEFDGKAKKAMKDGVH-DIPEDAQLETAENSSVIIIP-ECKRSHT 15886

Query: 804   GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHE 863
             G+   + + A N AG     Q +    VK     G   D+   +SD    +T    R+  
Sbjct: 15887 GK---YSITAKNKAG-----QKTANCRVKVMDVPGPPKDL--KVSD----ITRGSCRLSW 15932

Query: 864   ASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKS- 922
               P     D + G    K ++   +      +    +  V + L+        + +++  
Sbjct: 15933 KMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFG 15992

Query: 923   -----DPLKKKTDRAP---PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYR- 973
                  + +++ T R P   P PP  +      ++++ L WK P   GG+ +T Y V    
Sbjct: 15993 IGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLA 16052

Query: 974   -EVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCE 1032
              +        WR+ N + V E  + + +L E   Y+F+V A+N AG+  PSA      C+
Sbjct: 16053 WDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQ 16112

Query: 1033  EWTIAVPGPPHSLKCSE 1049
                   P  P S+   E
Sbjct: 16113 R-----PDMPPSIDLKE 16124



 Score =  150 bits (380), Expect = 8e-36
 Identities = 169/756 (22%), Positives = 290/756 (38%), Gaps = 92/756 (12%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             T+    +++L  S++G P P +TW K  + +   A     II++      L ++  +  D
Sbjct: 29457 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA-----IIDTTESYSLLIVDKVNRYD 29511

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRF-HAGASTMPLSFGVTPYGYASRFEI 405
               +Y   A N  G+ SA   V V    G     +       ++ +++ +      +    
Sbjct: 29512 AGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNN 29571

Query: 406   HFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERA 465
             +  +K + +  R  +T++  C   +             YR          +  L  G   
Sbjct: 29572 YIVEKREAAM-RAFKTVTTKCSKTL-------------YR----------ISGLVEG--- 29604

Query: 466   TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
               T  +     E +Y I    GE  E   A +        +   P  P  ++ ++  K  
Sbjct: 29605 --TMYYFRVLPENIYGI----GEPCETSDAVL--------VSEVPLVPAKLEVVDVTKST 29650

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
             + ++W++P  DGGS + GY ++ C+ GT+ W +            VT L EG  Y+FR+R
Sbjct: 29651 VTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 29710

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             A N+ G+  P      V   D      L+  P+       + T  + +  +  G P +L 
Sbjct: 29711 AQNEKGVSEPRETVTAVTVQD------LRVLPTID-----LSTMPQKTIHVPAGRPVELV 29759

Query: 646   VTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEG 705
             +  A R     SW   G +  E                +RV  E   K  +  + +    
Sbjct: 29760 IPIAGRPPPAASWFFAGSKLRES---------------ERVTVETHTKVAKLTIRETTIR 29804

Query: 706   KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESK 763
              +  + +   N  G    SE  +V ++ DK   P  P KI       TS+ +SWE  E  
Sbjct: 29805 DTGEYTLELKNVTGT--TSETIKVIIL-DKPGPPTGPIKI--DEIDATSITISWEPPELD 29859

Query: 764   DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823
                 L GY +E   A    W P + + V  S F    L  G  Y+FRV A N  G+  Y 
Sbjct: 29860 GGAPLSGYVVEQRDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYL 29918

Query: 824   QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTAS------RGRVHEASPPTFQKDALLGS 877
             Q SE IE +++I     P+          G+T +       G          +K+     
Sbjct: 29919 Q-SEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADR 29977

Query: 878   KPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPP 937
                   +P +      T +++  E  +  +T    + + +    S P+      APP  P
Sbjct: 29978 WVRVNKVPVTMTRYRSTGLTEGLE-YEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKP 30036

Query: 938   CDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYK 997
              +    ++ R S+ L W  P+  GG+++TGY +  ++V      +W + N        Y 
Sbjct: 30037 QNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQ---HEWTKCNTTPTKIREYT 30093

Query: 998   ISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE 1033
             +++L +   Y+F+V A N  G G P+ V    K  E
Sbjct: 30094 LTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTE 30129



 Score =  145 bits (366), Expect = 3e-34
 Identities = 132/461 (28%), Positives = 195/461 (42%), Gaps = 55/461 (11%)

Query: 367   VVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKF-DVSFGREGETMSLG 425
             V+ +   G F E    +GA        +T            D K+ DV     GET  L 
Sbjct: 24677 VIARNAAGNFSEPSDSSGA--------ITARDEIDAPNASLDPKYKDVIVVHAGETFVLE 24728

Query: 426   CRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG-ERATLTFSHLNKEDEGLYTIRV 484
               +   P      P++ W ++G  L  +     + S  ++ TL      + D G Y +++
Sbjct: 24729 ADIRGKPI-----PDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKL 24783

Query: 485   RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGY 544
                   +     V V D      G P  PL V  + A K Y+  +W  P  DGG+ I  Y
Sbjct: 24784 SNVGGTKSIPITVKVLDRP----GPPEGPLKVTGVTAEKCYL--AWNPPLQDGGANISHY 24837

Query: 545   FIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAA 604
              I+K E    SW+Q + T V+   + VT L+ G  YIFRV AVNK GIG P   S PV A
Sbjct: 24838 IIEKRETSRLSWTQVS-TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE-SGPVTA 24895

Query: 605   LDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSW-KPPGQ 663
              +P +                            PGPP+   V+  T+  +V++W +P   
Sbjct: 24896 CNPYKP---------------------------PGPPSTPEVSAITKDSMVVTWARPVDD 24928

Query: 664   RGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEP 723
              G E   Y +EK +     W + N +  +   R  +  L EG SY FRV   N+AGVGEP
Sbjct: 24929 GGTEIEGYILEKRDKEGVRWTKCNKKT-LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEP 24987

Query: 724   SEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSG 781
             SE +      D L  P  P     +  + +SV ++W +        + GY +E   A + 
Sbjct: 24988 SEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAAD 25047

Query: 782   KWEPCN-NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSE 821
             +W  C     ++G +FT   L     Y FR+ A+N+ G+ E
Sbjct: 25048 EWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGE 25088



 Score =  145 bits (365), Expect = 4e-34
 Identities = 179/719 (24%), Positives = 290/719 (40%), Gaps = 83/719 (11%)

Query: 638   PGPPTDLSVTEATRSYVVLSWKPP-GQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPR 696
             PGPP +    +  ++ V+  W+PP    G E I Y +EK +    + + +     ++  +
Sbjct: 14802 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCK 14861

Query: 697   FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
             +++  L EGK Y FRVR  N  G G P   ++  V  D    P AP K I    T  S++
Sbjct: 14862 YSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSML 14920

Query: 757   VSWEESKD-AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVN 815
             V W E KD    ++GY++E     S  W   N + +   +    GL+ G +Y+FRV A N
Sbjct: 14921 VKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAEN 14980

Query: 816   AAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDA-L 874
             AAG  ++S  S+       I     P   P ++D     T+S     E  PP F     +
Sbjct: 14981 AAGPGKFSPPSDPKTAHDPISPPGPP--IPRVTD-----TSSTTIELEWEPPAFNGGGEI 15033

Query: 875   LGSKPNKPSLPSSSQN--------LGQTEVSKVSETVQEELTPPPQKAAPQGK-SKSDPL 925
             +G   +K  + ++  +        + Q  V ++ E    +L      AA +G   ++ P+
Sbjct: 15034 VGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPV 15093

Query: 926   KKKTDRAPPSPPCDITCLESFR---------DSMVLGWKQPDKIGGAEITGYYVNYREVI 976
                  + PP+   D++     +          ++V G   P K+   E  G     R VI
Sbjct: 15094 TVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKE-EGELDKDRVVI 15152

Query: 977   DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
             D         NV   SE   K +  K++  Y   + A N  G    +A  E F       
Sbjct: 15153 D---------NVGTKSELIIKDALRKDHGRYV--ITATNSCGSKFAAARVEVFD------ 15195

Query: 1037  AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIK 1096
              VPGP   LK     +   +L W  P   G + +TG+ ++ K+AK     WR   E   +
Sbjct: 15196 -VPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM--HTWRQPIET--E 15250

Query: 1097  NVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG----TKEVVVNVDDDG 1152
                  + GL EG  Y FRV A N+ G G P ++ GP++A    G     + +        
Sbjct: 15251 RSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEI-GPILAVDPLGPPTSPERLTYTERTKS 15309

Query: 1153  VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
              I+L+++  +    S            D P  E  +K      +F    +D+  +Y   V
Sbjct: 15310 TITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRV 15369

Query: 1213  TDTDGIASS-------YLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQ 1265
                + I  S        +I ++E+   + L    +  T+ VK+   V I           
Sbjct: 15370 KAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHI----------- 15418

Query: 1266  AEKLSG--NAKVNYIFNEKEIFEGPK-----YKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
                ++G    K+ +  NE  + E P       K  + R+    E+ + K   ED+GTYT
Sbjct: 15419 PADVTGLPMPKIEWSKNE-TVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYT 15476



 Score =  139 bits (351), Expect = 2e-32
 Identities = 139/561 (24%), Positives = 228/561 (40%), Gaps = 59/561 (10%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P  P+DV+      + + I+WK P  DGGS I+GY I+K   G + W +CN+  V    +
Sbjct: 14580 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 14639

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
                GL EG+ Y FRVRA N  GI  PSR + P  A+DP +  ++  R S     ++   +
Sbjct: 14640 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSL----EVKRGD 14695

Query: 630   EEPSEGIVPGPP-------TDLSV---TEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAG 679
             E   +  + G P        D +V    E  +    L  +  G+   E            
Sbjct: 14696 EIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLS 14755

Query: 680   TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 739
              +N ++  ++L V+       D        + ++  N  G+ +      V      LD P
Sbjct: 14756 IDNSKKGESQLRVR-------DSLRPDHGLYMIKVENDHGIAKAPCTVSV------LDTP 14802

Query: 740   KAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEA--SVAGSGKWEPCNNNPVKGSR 795
               P   +      TSV+  WE   D    E++ Y +E         +W    +  ++  +
Sbjct: 14803 GPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTST-LRHCK 14861

Query: 796   FTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLT 855
             ++   L+ G+ Y+FRVRA N  G       S+ +  K   G   +PD  P + D      
Sbjct: 14862 YSVTKLIEGKEYLFRVRAENRFGPGPPCV-SKPLVAKDPFGPPDAPDK-PIVED-----V 14914

Query: 856   ASRGRVHEASPPTFQKDALLGSKPNKPSLPS--------SSQNLGQTEVSKVSETVQEEL 907
              S   + + + P      +LG    K  + S        S  N  +  V  + E +    
Sbjct: 14915 TSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVF 14974

Query: 908   TPPPQKAAPQGK--SKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEI 965
                 + AA  GK    SDP       +PP PP      ++   ++ L W+ P   GG EI
Sbjct: 14975 RVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEI 15033

Query: 966   TGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAV 1025
              GY+V+ + V      +W     K +    Y +  ++E   Y+ +V+A+N AG G P   
Sbjct: 15034 VGYFVDKQLV---GTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPG-- 15088

Query: 1026  SECFKCEEWTIAVPGPPHSLK 1046
                 + +  T+A P  P +++
Sbjct: 15089 ----ETQPVTVAEPQEPPAVE 15105



 Score =  134 bits (337), Expect = 7e-31
 Identities = 227/973 (23%), Positives = 378/973 (38%), Gaps = 127/973 (13%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFI-----DKCEVGTDSWSQCNDTPV 564
             P  P+ +K     K+ + +SWK P  DGGSP+  Y +     D      ++W QCN   V
Sbjct: 16012 PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDV 16071

Query: 565   KFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQ 624
             +  +F V  L+EG  Y FRV+AVN  G      VS+P A + P +  R    PS     +
Sbjct: 16072 EELQFTVEDLVEGGEYEFRVKAVNAAG------VSKPSATVGPCDCQRPDMPPSID-LKE 16124

Query: 625   IIVTEEEPSEGIV---PGPPTDLSVTEATRSYVVLSW-KPPGQR--GHEGIMYFVEKCEA 678
              +  EE  +  IV    G P           +  L+W K P ++    E ++Y       
Sbjct: 16125 FMEVEEGTNVNIVAKIKGVP-----------FPTLTWFKAPPKKPDNKEPVLYDT----- 16168

Query: 679   GTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDI 738
                    VN  +   +    +       +  + +   N+  +G  S+   + V+G +   
Sbjct: 16169 ------HVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNN--LGTASKEMRLNVLG-RPGP 16219

Query: 739   PKAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRF 796
             P  P K   S + D  + +SW   KD    ++  Y IE   A    W   ++ P K   +
Sbjct: 16220 PVGPIK-FESVSAD-QMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP-KECTY 16276

Query: 797   TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTA 856
             T   L+ G  Y+FR+ A N  G+ E   DSE    +       +PD     S     +T 
Sbjct: 16277 TIPKLLEGHEYVFRIMAQNKYGIGE-PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTV 16335

Query: 857   S--RGRVHEASPPT----FQKDALLGSKPNKPSLPSSSQNLGQT-EVSKVSETVQEELTP 909
             +         SP T      KD            P  +  LG + +V+ + E    +   
Sbjct: 16336 NWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRV 16395

Query: 910   PPQKAAPQGKSK--SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                 AA  G +   SDP   +   APP PP      +  + S  L W  P K GG+++TG
Sbjct: 16396 YAINAAGVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTG 16454

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             Y V Y+E  +G   +W +   K V      ++ LKE   Y+F+V A+N+AG+G P  V++
Sbjct: 16455 YIVEYKE--EG-KEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD 16511

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVH-----SGRTPVTGYFVDLKEAKA 1082
               + ++  ++   P   L  S   +D +V+     +      SG+ P T   V     + 
Sbjct: 16512 VIEMKDRLVS---PDLQLDASV--RDRIVVHAGGVIRIIAYVSGKPPPT---VTWNMNER 16563

Query: 1083  KEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS------DLAGPVVAE 1136
                Q   +   AI +  + ++  +     V+ + A N+AG  K +      D+ GPV   
Sbjct: 16564 TLPQEATIETTAISS-SMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPV--- 16619

Query: 1137  TRPGTKEVVVNVDDDGVISLNF--ECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTK 1194
                GT  +  N+ ++      F  E D  +P + +   K     E   R         T+
Sbjct: 16620 ---GTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEK----RESDRRAWTPVTYTVTR 16672

Query: 1195  MTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEI 1254
                   G+     Y   +   + I     ++  E    L +      P  P   +L V+ 
Sbjct: 16673 QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSE---ALVIREPITVPERP--EDLEVKE 16727

Query: 1255  LEKGQVRFWMQAEKLSGNAK-VNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDE 1313
             + K  V       K  G ++ +NY+   + I      K H   N  ++         ++ 
Sbjct: 16728 VTKNTVTLTWNPPKYDGGSEIINYVLESRLI---GTEKFHKVTNDNLLSRKYTVKGLKEG 16784

Query: 1314  GTYTFQLQ------DGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWE 1367
              TY +++        GK +  +  +   D         +F+ +  IR  G  F       
Sbjct: 16785 DTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIR-VGEAFA------ 16837

Query: 1368  VTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKK--DAGI 1425
             +TG  +   K KV+         W+KDE ++  D++   K    TL + +   K  D+G 
Sbjct: 16838 LTGRYSGKPKPKVS---------WFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGK 16888

Query: 1426  YEVILKDDRGKDK 1438
             Y V++++  G  K
Sbjct: 16889 YCVVVENSTGSRK 16901



 Score =  131 bits (330), Expect = 5e-30
 Identities = 219/1039 (21%), Positives = 387/1039 (37%), Gaps = 164/1039 (15%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             T+    ++ L  ++ G PEP++ W K    +++     K  ++      T  I  CD  D
Sbjct: 29058 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCE---KVSLQYTGKRATAVIKFCDRSD 29114

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYK-----GEFDETRFHAGASTMPLSFGVTPYGYAS 401
             + +Y  +  N  G  +   SV+VK        G+   +R      T+  S      G   
Sbjct: 29115 SGKYTLTVKNASG--TKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGG--- 29169

Query: 402   RFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS 461
                                            EI H+  E +        S   WV  +  
Sbjct: 29170 ------------------------------AEITHYIVERR------ETSRLNWV--IVE 29191

Query: 462   GERATLTF--SHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVK 517
             GE  TL++  + L K +E ++ +R   + G      S  +  R++   I   P  P +V 
Sbjct: 29192 GECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNS-FTIPSPPGIPEEV- 29249

Query: 518   CLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCN-DTPVKFARFPVTGLIE 576
                  K++III W +P  DGG+ I  Y +DK E  +  W++ N D  V   R  VT L+E
Sbjct: 29250 --GTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 29307

Query: 577   GRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGI 636
             G  Y FRV AVN  G   PS  S  ++  +P+                            
Sbjct: 29308 GCDYQFRVTAVNAAGNSEPSEASNFISCREPS---------------------------Y 29340

Query: 637   VPGPPTDLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSP 695
              PGPP+   V + T+  + L+W KP    G + + Y +E  E  T+ W RV+T   +++ 
Sbjct: 29341 TPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 29400

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
              F + DL  G+ Y FRV   N  G+ E SE+       ++++IP                
Sbjct: 29401 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP---------------- 29444

Query: 756   VVSWEESKDAKELV----GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLV-TGQSY-IF 809
                 E + D K+ V    G  +   V+ SG+  P      +G       ++ T +SY + 
Sbjct: 29445 --DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLL 29502

Query: 810   RVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGR--VHEASPP 867
              V  VN     +Y+ ++E         G  S  V   + D PG   + + +    ++   
Sbjct: 29503 IVDKVNRYDAGKYTIEAE------NQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTI 29556

Query: 868   TFQKDALLGSKPNKPSL---PSSSQNLGQTEVSKVSETVQE-----ELTPPPQKAAPQGK 919
             T++   + G  P    +     ++    +T  +K S+T+       E T    +  P+  
Sbjct: 29557 TWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENI 29616

Query: 920   SKSDPLKKKTDRA----PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREV 975
                    + +D       P  P  +  ++  + ++ L W++P   GG+ +TGY +   E 
Sbjct: 29617 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVL---EA 29673

Query: 976   IDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWT 1035
                   +W +      +   + +++L E   Y F++ A N  G+  P         ++  
Sbjct: 29674 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 29733

Query: 1036  I-----AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGL 1090
             +         P  ++     R   LV+    P+     P   +F     +K +E + R  
Sbjct: 29734 VLPTIDLSTMPQKTIHVPAGRPVELVI----PIAGRPPPAASWF--FAGSKLRESE-RVT 29786

Query: 1091  NEAAIKNVYLKVR--GLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNV 1148
              E   K   L +R   +++   Y   ++ +     G  S+    ++ + +PG     + +
Sbjct: 29787 VETHTKVAKLTIRETTIRDTGEYTLELKNV----TGTTSETIKVIILD-KPGPPTGPIKI 29841

Query: 1149  DDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPR---LEVESKGNKTKMTFKDLGMDDL 1205
             D+    S+    +          S   V   D+ R   L V     ++   F  L   + 
Sbjct: 29842 DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNE 29901

Query: 1206  GIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQ 1265
              ++    T+  GI  SYL  E     ++      + P  P   ++  ++   G    W  
Sbjct: 29902 YVFRVAATNRFGI-GSYLQSE-----VIECRSSIRIPGPPETLQI-FDVSRDGMTLTWYP 29954

Query: 1266  AEKLSGNAKVNYIFNEKEI 1284
              E   G+    YI   KE+
Sbjct: 29955 PEDDGGSQVTGYIVERKEV 29973



 Score =  131 bits (329), Expect = 6e-30
 Identities = 97/326 (29%), Positives = 140/326 (42%), Gaps = 46/326 (14%)

Query: 418   EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDE 477
             EGE +S+       P      P + W+++G  +  S  +        A L      + D 
Sbjct: 14400 EGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 14454

Query: 478   GLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAV 535
             G+YTI +  ++G               + ++ G P    D+K  +  K    ++W+ P  
Sbjct: 14455 GIYTITLENKLGSA---------TASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 14505

Query: 536   DGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFP 595
             DGG+PIL Y +++ E G  ++        K + + V  LI    Y FRV+AVNK+G G  
Sbjct: 14506 DGGTPILHYVLERREAGRRTYIPVMSGENKLS-WTVKDLIPNGEYFFRVKAVNKVGGGEY 14564

Query: 596   SRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVV 655
               +  PV A DP +                            P PP D+ V   T   + 
Sbjct: 14565 IELKNPVIAQDPKQP---------------------------PDPPVDVEVHNPTAEAMT 14597

Query: 656   LSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRC 714
             ++WKPP   G   IM Y +EK   G E W+R N  L V    +    L EGK Y FRVR 
Sbjct: 14598 ITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRA 14656

Query: 715   SNSAGVGEPSEATEVTVVGDKLDIPK 740
              N+AG+ EPS AT  T   D +D PK
Sbjct: 14657 ENAAGISEPSRATPPTKAVDPIDAPK 14682



 Score =  129 bits (323), Expect = 3e-29
 Identities = 129/471 (27%), Positives = 187/471 (39%), Gaps = 95/471 (20%)

Query: 288   VWEKENVKLHCSIAGWPEPRVTWYK-------NQVPINVHANPGKYIIESRYGMHTLEIN 340
             V E  NV +   I G P P +TW+K       N+ P+    +  K +++      TL I 
Sbjct: 16128 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTC---TLVIP 16184

Query: 341   GCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYA 400
                  DT  Y  +A+N  G  S               E R +      P      P G  
Sbjct: 16185 QSRRSDTGLYTITAVNNLGTAS--------------KEMRLNVLGRPGP------PVG-P 16223

Query: 401   SRFEIHFDDKFDVS-FGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTL 459
              +FE    D+  +S F  + +  S     VI                    +   WV   
Sbjct: 16224 IKFESVSADQMTLSWFPPKDDGGSKITNYVIEKR---------------EANRKTWVHVS 16268

Query: 460   WSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGA------PAAP 513
                +  T T   L +  E ++ I  +        + Y      D+E E A      P AP
Sbjct: 16269 SEPKECTYTIPKLLEGHEYVFRIMAQ--------NKYGIGEPLDSEPETARNLFSVPGAP 16320

Query: 514   LDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKF----ARF 569
                      ++ + ++W++P  DGGSP+ GY+++  +  +  W + N  P+K       +
Sbjct: 16321 DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSY 16380

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGLIEG  Y FRV A+N  G+G  S  S+P  A DP           AP         
Sbjct: 16381 KVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPI----------AP--------- 16421

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT 688
                     PGPP    VT+ T+S   L W PP + G   +  Y VE  E G E W++   
Sbjct: 16422 --------PGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEK-GK 16471

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 739
             +  V+  +  +  L EG  Y FRVR  N AG+GEP E T+V  + D+L  P
Sbjct: 16472 DKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP 16522



 Score =  125 bits (313), Expect = 5e-28
 Identities = 183/774 (23%), Positives = 298/774 (38%), Gaps = 129/774 (16%)

Query: 274   LHAPEFIIKP---RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIES 330
             L APE  I     ++H V    +++L  +  G P P   W K    +++ A+     I +
Sbjct: 28352 LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD-----IHT 28406

Query: 331   RYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
                  TL +  C+  D  +Y  +  N  G  S   +V V    G              P+
Sbjct: 28407 TDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-----------PGPI 28455

Query: 391   SFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPL 450
             +F     G A+                +   +  G R      I H+  E +        
Sbjct: 28456 TFKDVTRGSATLMW-------------DAPLLDGGAR------IHHYVVEKR------EA 28490

Query: 451   SPSKWVQTLWSGERATLTFSHLNKEDEGL-YTIRVRMGEYYEQYSAYVFVRDADAEIEGA 509
             S   W Q +   E+ T     +N   EG+ Y  RV     Y     Y       A  + A
Sbjct: 28491 SRRSW-QVI--SEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPA 28547

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P   LDV  ++ +K   +++W +P  DGGS I GY ++  + G+D W +   T  K   F
Sbjct: 28548 PPRRLDV--VDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT--KQLTF 28603

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTG---QII 626
              V  L+E   Y FRV+A N  G   P      V   +P      +  P+A  TG   Q+I
Sbjct: 28604 TVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEP------QIEPTADLTGITNQLI 28657

Query: 627   VTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRV 686
               +         G P  + V  + R    ++WK    R        +++ +  +    + 
Sbjct: 28658 TCK--------AGSPFTIDVPISGRPAPKVTWKLEEMR--------LKETDRVSITTTKD 28701

Query: 687   NTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKII 746
              T L VK       D   G S  + +   N+AGV   + +  V V+G    +    G I 
Sbjct: 28702 RTTLTVK-------DSMRGDSGRYFLTLENTAGV--KTFSVTVVVIGRPGPV---TGPIE 28749

Query: 747   PSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTG 804
              S  +  S V+SW E KD    E+  Y +E   +G+  W+  N++ VK ++     L   
Sbjct: 28750 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKY 28808

Query: 805   QSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV--- 861
               Y FRV + N  G+S+  + +  I           P V P+    P     S   +   
Sbjct: 28809 MEYSFRVSSENRFGVSKPLESAPII--------AEHPFVPPSAPTRPEVYHVSANAMSIR 28860

Query: 862   -----HEASPPTF-------QKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTP 909
                  H+             +++ +L  K NK  +P    N    +V+ + E ++ +   
Sbjct: 28861 WEEPYHDGGSKIIGYWVEKKERNTILWVKENK--VPCLECNY---KVTGLVEGLEYQFRT 28915

Query: 910   PPQKAAPQGKSK--SDPLKKKTDRAPPSPP--CDITCLESFRDSMVLGWKQPDKIGGAEI 965
                 AA   K+   S P+  +     P  P   D+T     R ++ L W  P   GG+++
Sbjct: 28916 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVT-----RSTVSLIWSAPAYDGGSKV 28970

Query: 966   TGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GY +  + V +   G+W + N   VS+  + ++ L E   Y+F+V A N AG+
Sbjct: 28971 VGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGV 29024



 Score =  122 bits (307), Expect = 2e-27
 Identities = 234/997 (23%), Positives = 368/997 (36%), Gaps = 139/997 (13%)

Query: 508   GAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFA 567
             G P +P  +   E  K  I + WK+P  +GGSPI GY I+K       + + N       
Sbjct: 15293 GPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTT 15352

Query: 568   RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALD---PAEKARLKSRPSAPWTGQ 624
              F V  L E + Y FRV+AVN++G   PS     V   D   P  K RL  R        
Sbjct: 15353 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDT----- 15407

Query: 625   IIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQ 684
             I V   EP    +P   T L + +       + W     +    I    +  +   E   
Sbjct: 15408 IKVKAGEPVH--IPADVTGLPMPK-------IEWS----KNETVIEKPTDALQITKEEVS 15454

Query: 685   RVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGK 744
             R   +  +  P+    D        + V  SN  G    +   EV       D P  P  
Sbjct: 15455 RSEAKTELSIPKAVREDKGT-----YTVTASNRLGSVFRNVHVEV------YDRPSPPRN 15503

Query: 745   IIPSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGK--WEPCNNNPVKGSRFTCHG 800
             +  +     S  ++W+   D    E+  Y I+   A   K  WE   N  V+  R+    
Sbjct: 15504 LAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVE-KRYGIWK 15562

Query: 801   LVTGQSYIFRVRAVNAAGLSEYSQDSEAI--------------EVKAAIGGGVSPDVCPA 846
             L+    Y FRVRAVN  G+S+  +  + +              +V A   G +     P 
Sbjct: 15563 LIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPP 15622

Query: 847   LSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEE 906
             L +    +T       E   P +       S+ ++  +        +  V ++ E V+ +
Sbjct: 15623 LDNGGSPITGYWLEKREEGSPYW-------SRVSRAPITKVGLKGVEFNVPRLLEGVKYQ 15675

Query: 907   LTPPPQKAAPQG--KSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
                    AA  G     SDP        PP PP      +  + S+ LGWK P K GG+ 
Sbjct: 15676 FRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSP 15735

Query: 965   ITGYYVNYREVIDGVPGKWREANV--KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
             I GY V  +E  +G    W+  N   K ++     + NLKE   Y+F+V A+N AG   P
Sbjct: 15736 IKGYIVEMQE--EGTTD-WKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEP 15792

Query: 1023  SAVSECFKC----EEWTIAVP-GPPHSLKCSEVRKDSLVLQWKPPVHSGR-TPVTGYFVD 1076
             S  +         EE  + +  G    L C    +  +     P V  GR TP + +  D
Sbjct: 15793 SDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRI-----PAVIKGRPTPKSSWEFD 15847

Query: 1077  LKEAKAKEDQWRGLNE-----AAIKNVYLKVRGLKEGVSYVFRVRAINQAGVG------K 1125
              K  KA +D    + E      A  +  + +   K   +  + + A N+AG        K
Sbjct: 15848 GKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVK 15907

Query: 1126  PSDLAGP-----VVAETRPGTKEVVVNVDDDGVISLN-FECDKMTPKSEFSWSKDYVSTE 1179
               D+ GP     V   TR   +      DDDG   +  +  +K T   + +W+K      
Sbjct: 15908 VMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGK-AWTK------ 15960

Query: 1180  DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEH 1239
                   V      T     DL  +    +     +  GI        E ++R  A    +
Sbjct: 15961 ------VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPV----ETIQRTTARDPIY 16010

Query: 1240  KFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFE--GPKYKMHIDRN 1297
               P  P+K  L + ++ K  V    +  K  G + V +   E   ++  G K +     N
Sbjct: 16011 P-PDPPIK--LKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN 16067

Query: 1298  TGIIEMFMEKLQDEDEG-TYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQ 1356
                +E     ++D  EG  Y F++   KA N + V          +  A     +  R  
Sbjct: 16068 KRDVEELQFTVEDLVEGGEYEFRV---KAVNAAGVS---------KPSATVGPCDCQRPD 16115

Query: 1357  GPHFVEYLSW-EVTGECNVLLKCKVANIKKETHIVWYK------DEREISVDEKHDFK-- 1407
              P  ++   + EV    NV +  K+  +   T + W+K      D +E  + + H  K  
Sbjct: 16116 MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPT-LTWFKAPPKKPDNKEPVLYDTHVNKLV 16174

Query: 1408  -DGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
              D  CTL+I +  + D G+Y +   ++ G     ++L
Sbjct: 16175 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 16211



 Score =  121 bits (304), Expect = 5e-27
 Identities = 115/467 (24%), Positives = 177/467 (37%), Gaps = 86/467 (18%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             TV   + ++L   + G P P V W K++   ++  +P +  I++R       +      D
Sbjct: 18212 TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSD 18270

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
               +Y  +A N  G   AYA+V V    G     +                          
Sbjct: 18271 GGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKI------------------------- 18305

Query: 407   FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                  DVS  R        C V   P       EIQ Y     L   +  + +WS   AT
Sbjct: 18306 ----VDVSSDR--------CTVCWDPPEDDGGCEIQNY----ILEKCETKRMVWSTYSAT 18349

Query: 467   L-----TFSHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCL 519
             +     T + L + +E ++ +R   ++G      S  V  +         P  P   +  
Sbjct: 18350 VLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTK----YDKPGRPDPPEVT 18405

Query: 520   EANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRS 579
             + +K+ + + W  P  DGG  I GYF++K E  +  W   N + +   R  V  L+    
Sbjct: 18406 KVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHE 18465

Query: 580   YIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPG 639
             Y FRV+A N++GIG PS  S PV A DP E                            PG
Sbjct: 18466 YQFRVKAENEIGIGEPSLPSRPVVAKDPIEP---------------------------PG 18498

Query: 640   PPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCE------AGTENWQRVNTELPVK 693
             PPT+  V + T+  + L W  P   G   I+ +V +        +  E W+R N    + 
Sbjct: 18499 PPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLV 18558

Query: 694   SPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
                F +  L E + Y FRV   N  G+G P+E  E     + L+ P+
Sbjct: 18559 RKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPE 18605



 Score =  120 bits (300), Expect = 1e-26
 Identities = 118/471 (25%), Positives = 184/471 (39%), Gaps = 81/471 (17%)

Query: 277   PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
             P   +   ++++   E++K+   + G P P ++W K+  P+       +  +E       
Sbjct: 24312 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLK---QTTRVNVEETATSTV 24368

Query: 337   LEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTP 396
             L I   + +D  +Y  +A N  G  +   SV+V    G                     P
Sbjct: 24369 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--------------------PP 24408

Query: 397   YGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWV 456
              G     E+  D    V    E    + GC++      K       W+     ++     
Sbjct: 24409 VGPVRFDEVSAD---FVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVA----- 24460

Query: 457   QTLWSGERATLTFSHLNKEDEGLYTIRV----RMGEYYEQYSAYVFVRDADAEIEGAPAA 512
                    R T+  + L    E  Y  R+    R G+     S  V V+    E  G P  
Sbjct: 24461 -------RTTIKITKLKTGTE--YQFRIFAENRYGKSAPLDSKAVIVQYPFKE-PGPPGT 24510

Query: 513   PLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVT 572
             P        +KD +++ W +P  DGG+ I+GY +++ E  +  W + N TP++  +F  T
Sbjct: 24511 PF---VTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTT 24567

Query: 573   GLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEP 632
             GL EG  Y F+V A N +GIG PS+VSE   A DP +                       
Sbjct: 24568 GLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDP---------------------- 24605

Query: 633   SEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELP 691
                  PG P  + +   TR+ V L WK P   G   I  Y VEK +     W + +    
Sbjct: 24606 -----PGRPEAIVI---TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASF-TN 24656

Query: 692   VKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKA 741
             V    F +  L E + Y FRV   N+AG   EPS+++      D++D P A
Sbjct: 24657 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNA 24707



 Score =  117 bits (293), Expect = 9e-26
 Identities = 95/316 (30%), Positives = 144/316 (45%), Gaps = 39/316 (12%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P+ PLD+   +A + +I I+WK P  +GGSPI+GY ++ C VGT+ W + N  P+K  +F
Sbjct: 14285 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 14344

Query: 570   PV-TGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVT 628
              V  G++  + Y+ RVRAVN +G+  PS +SE V A DP  K  +        T  IIV 
Sbjct: 14345 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLE-----THDIIVI 14399

Query: 629   EEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNT 688
             E E     +P P   + V         +SW   G+         V+  +  T     ++ 
Sbjct: 14400 EGEKLS--IPVPFRAVPVP-------TVSWHKDGKE--------VKASDRLTMKNDHISA 14442

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPS 748
              L V  P+    D        + +   N   +G  + +  V V+G    +P     I  S
Sbjct: 14443 HLEV--PKSVRADAG-----IYTITLENK--LGSATASINVKVIG----LPGPCKDIKAS 14489

Query: 749   RNTDTSVVVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQS 806
               T +S  ++WE  E      ++ Y +E   AG   + P  +   K S +T   L+    
Sbjct: 14490 DITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLS-WTVKDLIPNGE 14548

Query: 807   YIFRVRAVNAAGLSEY 822
             Y FRV+AVN  G  EY
Sbjct: 14549 YFFRVKAVNKVGGGEY 14564



 Score =  117 bits (292), Expect = 1e-25
 Identities = 89/308 (28%), Positives = 141/308 (45%), Gaps = 18/308 (5%)

Query: 922   SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPG 981
             SDP+  +     P  P          +S+ L W +P+  GG+EI  Y +  RE       
Sbjct: 28140 SDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKST--- 28196

Query: 982   KW-REANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
             +W +  + + +SE  +K++ L E   Y+F V A N AG+G  S +S   KC E  +  PG
Sbjct: 28197 RWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCRE-PVNPPG 28255

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVY 1099
             PP  +K ++  K ++ L+W  PV  G   + GY +++   KA    W  +N EA +K  Y
Sbjct: 28256 PPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEM--CKADLGDWHKVNAEACVKTRY 28313

Query: 1100  LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVV-------NVDDDG 1152
               V  L+ G  Y FRV AIN AG G   ++ G + A  R    E+ +       +V   G
Sbjct: 28314 -TVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAG 28372

Query: 1153  VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
                  F   +  P     WSK    +  S R ++ +  + + +T ++   +D G Y+  V
Sbjct: 28373 ASIRLFIAYQGRPTPTAVWSKP--DSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV 28430

Query: 1213  TDTDGIAS 1220
              +  G  S
Sbjct: 28431 ENNSGSKS 28438



 Score =  116 bits (290), Expect = 2e-25
 Identities = 133/548 (24%), Positives = 220/548 (40%), Gaps = 61/548 (11%)

Query: 638   PGPPTD-LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             PGPP   +   E +  +VV+SW+PP   G   I  Y VEK +  T  W  V+    V   
Sbjct: 24405 PGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSAT--VART 24462

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
                +  L  G  Y FR+   N  G   P ++  V +V      P  PG    +  +   +
Sbjct: 24463 TIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAV-IVQYPFKEPGPPGTPFVTSISKDQM 24521

Query: 756   VVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRA 813
             +V W E  +    +++GY++E     S  W   N  P++ ++F   GL  G  Y F+V A
Sbjct: 24522 LVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA 24581

Query: 814   VNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG-----LTASRGRVHEASPPT 868
              N  G+ + S+ SE           V+ D C    D PG      +T +   +    P  
Sbjct: 24582 ENIVGIGKPSKVSECF---------VARDPC----DPPGRPEAIVITRNNVTLKWKKPAY 24628

Query: 869   FQKDALLGSKPNKPSLP------SSSQNLGQTE--VSKVSETVQEELTPPPQKAAPQGKS 920
                  + G    K  LP      +S  N+ +TE  VS + E  + E     + AA     
Sbjct: 24629 DGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSE 24688

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
              SD     T R     P + +    ++D +V+        G   +    +  + + D V 
Sbjct: 24689 PSDSSGAITARDEIDAP-NASLDPKYKDVIVV------HAGETFVLEADIRGKPIPDVVW 24741

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAA------MNMAGLGAPSAVSECFKCEEW 1034
              K  +   +  +    K +  K  +V +  +        + ++ +G   ++    K    
Sbjct: 24742 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVK---- 24797

Query: 1035  TIAVPGPPHS-LKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
              +  PGPP   LK + V  +   L W PP+  G   ++ Y ++ +E       W  ++  
Sbjct: 24798 VLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS--WTQVS-T 24854

Query: 1094  AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA------ETRPGTKEVVVN 1147
              ++ +  KV  L  G  Y+FRV A+N+ G+G+P + +GPV A         P T EV   
Sbjct: 24855 EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE-SGPVTACNPYKPPGPPSTPEVSAI 24913

Query: 1148  VDDDGVIS 1155
               D  V++
Sbjct: 24914 TKDSMVVT 24921



 Score =  115 bits (289), Expect = 3e-25
 Identities = 166/757 (21%), Positives = 275/757 (36%), Gaps = 129/757 (17%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             E +K++  IAG P P ++W K+ + I   A   +  I S      L +  C   DT QY 
Sbjct: 25805 EVLKINADIAGRPLPVISWAKDGIEIEERA---RTEIISTDNHTLLTVKDCIRRDTGQYV 25861

Query: 352   ASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF-GVTPYGYASRFEIHFDDK 410
              +  NV G  S   +  V       D+    AG    PL   G+T             +K
Sbjct: 25862 LTLKNVAGTRSVAVNCKV------LDKPGPPAG----PLEINGLTA------------EK 25899

Query: 411   FDVSFGREGET--MSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGE--RAT 466
               +S+GR  E     +   +V   E  H    + W              T+  GE    +
Sbjct: 25900 CSLSWGRPQEDGGADIDYYIVEKRETSH----LAW--------------TICEGELQMTS 25941

Query: 467   LTFSHLNKEDEGLYTI----RVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEAN 522
                + L K +E ++ +    +  +GE  E     V ++  D      P+ P  ++     
Sbjct: 25942 CKVTKLLKGNEYIFRVTGVNKYGVGEPLES----VAIKALDPFT--VPSPPTSLEITSVT 25995

Query: 523   KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIF 582
             K+ + + W +P  DGGS I GY I++ E  +  W + N  PV   R   TGL EG  Y +
Sbjct: 25996 KESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEY 26055

Query: 583   RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
             RV A N  G+  PS  S  + A DP                             +P PP+
Sbjct: 26056 RVYAENAAGLSLPSETSPLIRAEDPV---------------------------FLPSPPS 26088

Query: 643   DLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFD 701
                + ++ ++ + ++W KP    G     Y VE  ++   +W+     L  +   + +  
Sbjct: 26089 KPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL--RGTEYTISG 26146

Query: 702   LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK-------LDIPKAPGKIIPSRNTDTS 754
             L  G  Y FRV+  N  G  +PS++++  +  ++       +D       I+ +  + T 
Sbjct: 26147 LTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTM 26206

Query: 755   VV---------VSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQ 805
              V         V W +         Y        S   E  N N       T   +++  
Sbjct: 26207 TVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 26266

Query: 806   SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEAS 865
             S    V+ ++  G        +  +  A +   V         +  GG       + +  
Sbjct: 26267 SLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV--------PENDGGAPVKNYHIEKRE 26318

Query: 866   PPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPL 925
                  K A +    N   L     NL +  +     + + E          +G       
Sbjct: 26319 A---SKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEG------- 26368

Query: 926   KKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWRE 985
              K T++  P     +T +   +DS+ L W +P+  GG+ I  Y V   E ++     W +
Sbjct: 26369 VKITEKPSPPEKLGVTSIS--KDSVSLTWLKPEHDGGSRIVHYVV---EALEKGQKNWVK 26423

Query: 986   ANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
               V       + +S L+EN  Y F+V A N AGL  P
Sbjct: 26424 CAV--AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 26458



 Score =  113 bits (282), Expect = 2e-24
 Identities = 82/300 (27%), Positives = 136/300 (45%), Gaps = 26/300 (8%)

Query: 934   PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
             P PP          D M L W  P   GG+E+TG++V  +E    +   W++ N   +S 
Sbjct: 27757 PGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSIL---WQKVNTSPISG 27813

Query: 994   EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVP--GPPHSLKCSEVR 1051
               Y+ + L E + YQF+V A N AGL +PS  S+      +T+AV    PP +    +V 
Sbjct: 27814 REYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK------FTLAVSPVDPPGTPDYIDVT 27867

Query: 1052  KDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSY 1111
             ++++ L+W PP+  G + + GY ++ ++     ++W   N   +      V GL  G  Y
Sbjct: 27868 RETITLKWNPPLRDGGSKIVGYSIEKRQGN---ERWVRCNFTDVSECQYTVTGLSPGDRY 27924

Query: 1112  VFRVRAINQAG-VGKPSDLAGPVVAETRPGTKEVVVNVDD---DGVISLNFECDKMT--- 1164
              FR+ A N  G +  PS  +G ++  TR      +V       DG+I  + E  ++    
Sbjct: 27925 EFRIIARNAVGTISPPSQSSGIIM--TRDENVPPIVEFGPEYFDGLIIKSGESLRIKALV 27982

Query: 1165  ---PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
                P    +W KD V  E    +E+      T +  +D   D  G+Y+ +  +  G A +
Sbjct: 27983 QGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKA 28042



 Score =  112 bits (279), Expect = 4e-24
 Identities = 71/232 (30%), Positives = 103/232 (44%), Gaps = 28/232 (12%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P  P   +     KD ++++W +P  DGG+ I GY ++K +     W++CN   +   R 
Sbjct: 24902 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRL 24961

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGL EG SY FRV A N  G+G PS  S    A D                       
Sbjct: 24962 RVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDAL--------------------- 25000

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT 688
                     PGPP++  VT+ +RS V L+W  P   G   +  Y VE  EA  + W     
Sbjct: 25001 ------YPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTP 25054

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
                ++  +F +  L E   Y FR+   NS GVGEP+      V  ++++ P+
Sbjct: 25055 PTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 25106



 Score =  108 bits (269), Expect = 6e-23
 Identities = 127/511 (24%), Positives = 214/511 (41%), Gaps = 52/511 (10%)

Query: 638   PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
             PGPP  + + E +   + +SW PP   G   I  Y VEK E  +  W  V+  +   S +
Sbjct: 25488 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIK 25547

Query: 697   FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
               +  L  G  Y FRV   N  G    SE++ V V       P  PG       T ++++
Sbjct: 25548 --IVRLTTGSEYQFRVCAENRYGKSSYSESSAV-VAEYPFSPPGPPGTPKVVHATKSTML 25604

Query: 757   VSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             V+W+   +     ++GY++E     S  W   N   +  ++    GL  G  Y +RV A 
Sbjct: 25605 VTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAE 25664

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVC-PALSDEPGGLTASRGRVHEASPPTFQKDA 873
             N AG+ + S+  E +  +         D C P    E   +T     +  + P       
Sbjct: 25665 NIAGIGKCSKSCEPVPAR---------DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAK 25715

Query: 874   LLGSKPNKPSLPS------SSQNLGQT--EVSKVSETVQEELTPPPQKAAPQGKSKSD-- 923
             + G    +  LP       +  N+ +T  EV++++E  + E     + AA      S+  
Sbjct: 25716 ITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSEST 25775

Query: 924   -PLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGY---YVNYREVIDGV 979
              P+  K D  PP    D+     FRD +V+   +  KI  A+I G     +++ +  DG+
Sbjct: 25776 GPIIVKDDVEPPRVMMDV----KFRDVIVVKAGEVLKI-NADIAGRPLPVISWAK--DGI 25828

Query: 980   PGKWREANVKAVSEEAYKISNLKENM---VYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
               + R A  + +S + + +  +K+ +     Q+ +   N+AG       S    C+   +
Sbjct: 25829 EIEER-ARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG-----TRSVAVNCK--VL 25880

Query: 1037  AVPGPPHS-LKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 1095
               PGPP   L+ + +  +   L W  P   G   +  Y V+ +E       W  + E  +
Sbjct: 25881 DKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE--TSHLAWT-ICEGEL 25937

Query: 1096  KNVYLKVRGLKEGVSYVFRVRAINQAGVGKP 1126
             +    KV  L +G  Y+FRV  +N+ GVG+P
Sbjct: 25938 QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 25968



 Score =  107 bits (267), Expect = 1e-22
 Identities = 81/279 (29%), Positives = 125/279 (44%), Gaps = 45/279 (16%)

Query: 462   GERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEA 521
             G ++ L      ++D G Y I         +++A      A  E+   P   LD+K +  
Sbjct: 15156 GTKSELIIKDALRKDHGRYVITAT-NSCGSKFAA------ARVEVFDVPGPVLDLKPVVT 15208

Query: 522   NKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYI 581
             N+   +++W  P  DGGS I G+ I++ +    +W Q  +T  + ++  +TGL+EG+ Y 
Sbjct: 15209 NRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIET--ERSKCDITGLLEGQEYK 15266

Query: 582   FRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPP 641
             FRV A NK G G P  +  P+ A+DP                               GPP
Sbjct: 15267 FRVIAKNKFGCGPPVEIG-PILAVDPL------------------------------GPP 15295

Query: 642   TD---LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRF 697
             T    L+ TE T+S + L WK P   G   I  Y +EK      +++RVN  L   +  F
Sbjct: 15296 TSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSF 15354

Query: 698   ALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
              + +L E + Y FRV+  N  G  EPS    V +  D++
Sbjct: 15355 LVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEV 15393



 Score =  103 bits (256), Expect = 2e-21
 Identities = 108/504 (21%), Positives = 202/504 (40%), Gaps = 70/504 (13%)

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            T   + +W+KD          ++    N   +T   +G  D G Y+C  ++  G      
Sbjct: 7238 TAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAG------ 7291

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIF--NE 1281
              ++     L +    +F    +K      I++  Q  F     K+ G+ ++  ++  +E
Sbjct: 7292 --KDSCSAQLGVQEPPRF----IKKLEPSRIVK--QDEFTRYECKIGGSPEIKVLWYKDE 7343

Query: 1282 KEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKL 1341
             EI E  K++M    +  ++E  M  L  ED G YT +  +   +  S+  L      K+
Sbjct: 7344 TEIQESSKFRMSFVDSVAVLE--MHNLSVEDSGDYTCEAHNAAGSASSSTSL------KV 7395

Query: 1342 QKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVD 1401
            ++   F+++       PH +E L        +V L+C++       H+ WYKD+RE+   
Sbjct: 7396 KEPPIFRKK-------PHPIETLK-----GADVHLECELQG-TPPFHVSWYKDKRELRSG 7442

Query: 1402 EKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKI 1459
            +K+    ++ + ++ I      D G Y+    +D G D     +  +A    + ++    
Sbjct: 7443 KKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDIS 7502

Query: 1460 ALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN 1519
             +   ++++Q+T EG +  S V +            G  +R SD +    +     LQ +
Sbjct: 7503 TVVGKEVQLQTTIEGAEPISVVWF---------KDKGEIVRESDNIWISYSENIATLQFS 7553

Query: 1520 EPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLP 1579
               P + GKY  ++             +     E +A    L+ A I EK         P
Sbjct: 7554 RVEPANAGKYTCQI------------KNDAGMQECFATLSVLEPATIVEK---------P 7592

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
            + + +  G    L C V G P     W K+ K L SD+   + F   + +   I  V+ +
Sbjct: 7593 ESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISF-FNKVSGLKIINVAPS 7651

Query: 1640 DSGKYGLVVKNKYGSETSDFTVSV 1663
            DSG Y   V+N  G ++   ++ V
Sbjct: 7652 DSGVYSFEVQNPVGKDSCTASLQV 7675



 Score =  103 bits (256), Expect = 2e-21
 Identities = 71/193 (36%), Positives = 91/193 (47%), Gaps = 7/193 (3%)

Query: 638   PGPPTD-LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             PGPP   L VT  T     L+W PP Q G   I  Y +EK E    +W +V+TE  V++ 
Sbjct: 24802 PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTE--VQAL 24859

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
              + +  L  G  Y FRV   N  G+GEP E+  VT   +    P  P     S  T  S+
Sbjct: 24860 NYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTAC-NPYKPPGPPSTPEVSAITKDSM 24918

Query: 756   VVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRA 813
             VV+W    D    E+ GY +E       +W  CN   +   R    GL  G SY FRV A
Sbjct: 24919 VVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAA 24978

Query: 814   VNAAGLSEYSQDS 826
              NAAG+ E S+ S
Sbjct: 24979 ENAAGVGEPSEPS 24991



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 161/728 (22%), Positives = 271/728 (37%), Gaps = 135/728 (18%)

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             VF R  DA     P  P + K  + ++  + ++W +P  DGG+P+ GY ++  E   D W
Sbjct: 24992 VFYRACDALYP--PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW 25049

Query: 557   SQCND-TPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKS 615
             + C   T ++  +F VT L E   Y FR+ A+N  G+G P+ +   V A +  E   ++ 
Sbjct: 25050 TTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIEL 25109

Query: 616   RPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQ---RGHEGIMYF 672
                     +++V                L  +   R +V +  +P  +      EGI+  
Sbjct: 25110 DAD---LRKVVV----------------LRASATLRLFVTIKGRPEPEVKWEKAEGIL-- 25148

Query: 673   VEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV 732
                         R   E+        + ++    S  + +   N++G    S+   V V 
Sbjct: 25149 ----------TDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSG----SKTAFVNV- 25193

Query: 733   GDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCNNNP 790
                LD P AP  +        SV +SWE        ++  Y +E        +    NN 
Sbjct: 25194 -RVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNC 25252

Query: 791   VKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDE 850
              K + F    L  G SY FRV A N  G+   ++ +E ++V             P L   
Sbjct: 25253 TK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSE-----------PPL--P 25298

Query: 851   PGGLTASRGRVHEASPPTFQKDALLGSKPN----KPSLPSSSQNLGQTEVSKVSETVQEE 906
             PG +T      + A+    + ++  GSK      +     S +    T+V  +  T+   
Sbjct: 25299 PGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATI-SG 25357

Query: 907   LTPPPQ----KAAPQGKSKSDP-----------LKKKTDRAPPSPPCDITCLESF----- 946
             LT   +     AA   K +SDP           ++ K     P    ++   E       
Sbjct: 25358 LTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVP 25417

Query: 947   ---RDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKE 1003
                R    + W++ D     E T   V+  + +  +  K  EA+ + V      +SN   
Sbjct: 25418 FKGRPQATVNWRK-DGQTLKETTRVNVSSSKTVTSLSIK--EASKEDVGTYELCVSNSAG 25474

Query: 1004  NMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPV 1063
             ++     +  ++  G   P  + E   C+  TI+                     W PP 
Sbjct: 25475 SITVPITIIVLDRPGPPGPIRIDE-VSCDSITIS---------------------WNPPE 25512

Query: 1064  HSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGV 1123
             + G   ++ Y V+ KE  +    W  +++ A+    +K+  L  G  Y FRV A N+ G 
Sbjct: 25513 YDGGCQISNYIVEKKETTS--TTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGK 25569

Query: 1124  GKPSDLAGPVVAE------TRPGTKEVV------------VNVDDDGVISLNFECDKMTP 1165
                S+ +  VVAE        PGT +VV            V V+D G   + +  +    
Sbjct: 25570 SSYSE-SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLE-YKE 25627

Query: 1166  KSEFSWSK 1173
             +S   WSK
Sbjct: 25628 RSSILWSK 25635



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 84/340 (24%), Positives = 135/340 (39%), Gaps = 45/340 (13%)

Query: 274   LHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYII-ESRY 332
             + AP F  + R+  V  + N  L C + G P+P V WY+    I   A+  KY I E + 
Sbjct: 30925 IQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII--ADGLKYRIQEFKG 30982

Query: 333   GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF 392
             G H L I     +D   Y+  A N  G +S  AS+ V+         + H   +   +  
Sbjct: 30983 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEV------PAKIHLPKTLEGMGA 31036

Query: 393   GVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSP 452
                  G     +I F  K D                          P I W +    +  
Sbjct: 31037 VHALRGEVVSIKIPFSGKPD--------------------------PVITWQKGQDLIDN 31070

Query: 453   SKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPA 511
             +   Q + +    +L F + + ++D G Y +  +     +Q       +  + ++   P 
Sbjct: 31071 NGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQ-------KTVELDVADVPD 31123

Query: 512   APLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPV 571
              P  VK  + ++D + ++W +PA DGGS I  Y ++KC    + W +      +  R+ V
Sbjct: 31124 PPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ--ARETRYTV 31181

Query: 572   TGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKA 611
               L    SY FRV A NK G+  PS  SEP    +   +A
Sbjct: 31182 INLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRA 31221



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 118/540 (21%), Positives = 205/540 (37%), Gaps = 75/540 (13%)

Query: 1146 VNVDDDGVISLNFECDKMTPKS-EFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDD 1204
            V++D     S +FEC     +    +WSKD           +   GN   +    +G  D
Sbjct: 6278 VSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGD 6337

Query: 1205 LGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWM 1264
             G Y+C  T+  G            K + +     K P   VK   A ++ ++G+    +
Sbjct: 6338 SGQYTCQATNDVG------------KDMCSAQLSVKEPPKFVKKLEASKVAKQGES---I 6382

Query: 1265 QAE-KLSGNA--KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQ 1321
            Q E K+SG+   KV++  N+ E+ E  KY M    +  ++ +   +   ED G Y  +  
Sbjct: 6383 QLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTI--NEASAEDSGDYICEAH 6440

Query: 1322 DGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVA 1381
            +G      +  L               +   +  Q P  V  L        +V+L+C+++
Sbjct: 6441 NGVGDASCSTALT-------------VKAPPVFTQKPSPVGALKGS-----DVILQCEIS 6482

Query: 1382 NIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKS 1439
                   +VW KD +++   +K     K    +L I      D G Y     ++ G D  
Sbjct: 6483 GTPP-FEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTC 6541

Query: 1440 RLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAI 1499
               +  +     + ++     L    +++++  EG Q  S V  +++D        G  I
Sbjct: 6542 SCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVV--WLKD-------RGEVI 6592

Query: 1500 RYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQ 1559
            R S+  +         LQ+  P  ++ GKY+ ++             +     E  A   
Sbjct: 6593 RESENTRISFIDNIATLQLGSPEASNSGKYICQI------------KNDAGMRECSAVLT 6640

Query: 1560 RLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHC 1619
             L+ A I EK         P+ +T+  G    L C V G P     W K+ + L++D   
Sbjct: 6641 VLEPARIIEK---------PEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKH 6691

Query: 1620 NLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLK 1679
            ++ F   + A   I     +D G Y   VKN  G   S+ TVSV + +     + +  LK
Sbjct: 6692 HITF-INKVASLKIPCAEMSDKGLYSFEVKNSVGK--SNCTVSVHVSDRIVPPSFIRKLK 6748



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 111/507 (21%), Positives = 197/507 (38%), Gaps = 72/507 (14%)

Query: 1162 KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
            K TP  +  W KD V     P+  +  +G+ + +    +     G Y+C VT+  G    
Sbjct: 5354 KGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVG---- 5409

Query: 1222 YLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIF-- 1279
                 +    +L ++   KF    VK   A +I++ G         K++G+ ++  ++  
Sbjct: 5410 ----SDSCTTMLLVTEPPKF----VKKLEASKIVKAGDSS--RLECKIAGSPEIRVVWFR 5459

Query: 1280 NEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD-GKATNHSTVVLVGDVF 1338
            NE E+    KY+M    +  +I+  M  L  ED G +  + Q+   +T+ ST V+V    
Sbjct: 5460 NEHELPASDKYRMTFIDSVAVIQ--MNNLSTEDSGDFICEAQNPAGSTSCSTKVIV---- 5513

Query: 1339 KKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREI 1398
                      ++  +    P  VE L         V L+C+++       +VWYKD+R++
Sbjct: 5514 ----------KEPPVFSSFPPIVETLK-----NAEVSLECELSG-TPPFEVVWYKDKRQL 5557

Query: 1399 SVDEKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVC 1456
               +K+    K+   ++ I      D G Y    +++ G D     +  +     + ++ 
Sbjct: 5558 RSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLN 5617

Query: 1457 KKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWL 1516
                ++    ++Q++ EG Q       +V+ LK         IR S+ ++         L
Sbjct: 5618 SLTVVAGEPAELQASIEGAQ-----PIFVQWLK----EKEEVIRESENIRITFVENVATL 5668

Query: 1517 QINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLG 1576
            Q  +  P + GKY+ ++             +     E  A    L+ A I EK       
Sbjct: 5669 QFAKAEPANAGKYICQI------------KNDGGMRENMATLMVLEPAVIVEK------- 5709

Query: 1577 GLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGV 1636
                 +T+  G+   L C V G P   V W K+ K L S       F   + +   I  V
Sbjct: 5710 --AGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLRILSV 5766

Query: 1637 STADSGKYGLVVKNKYGSETSDFTVSV 1663
               D+G Y   V+N  G  +    V V
Sbjct: 5767 ERQDAGTYTFQVQNNVGKSSCTAVVDV 5793



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 124/594 (20%), Positives = 223/594 (37%), Gaps = 84/594 (14%)

Query: 1100 LKVRGLKEGVSYVFRVRAINQAGVGKPSD---LAGPVVAETRPGTKEVVVNVDDDGVISL 1156
            L++  L    S  +   A N AG    S    +  P +   +P   E +   D      +
Sbjct: 7363 LEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGAD------V 7416

Query: 1157 NFECDKM-TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDT 1215
            + EC+   TP    SW KD        + ++ S+   T +   ++   D+G Y C  T+ 
Sbjct: 7417 HLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATND 7476

Query: 1216 DGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV 1275
             G         +     +AL    +F  V   S+++  + ++ Q++       + G   +
Sbjct: 7477 VG--------SDTCVGSIALKAPPRF--VKKLSDISTVVGKEVQLQ-----TTIEGAEPI 7521

Query: 1276 NYI-FNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLV 1334
            + + F +K         + I  +  I  +   +++  + G YT Q+++          L 
Sbjct: 7522 SVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATL- 7580

Query: 1335 GDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKD 1394
                  L+     ++ E I+             VT      L+C VA    E    W+KD
Sbjct: 7581 ----SVLEPATIVEKPESIK-------------VTTGDTCTLECTVAGTP-ELSTKWFKD 7622

Query: 1395 EREISVDEKH--DFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELM 1452
             +E++ D K+   F + +  L I   +  D+G+Y   +++  GKD     L         
Sbjct: 7623 GKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASL--------- 7673

Query: 1453 MEVCKKIALSATDLKIQSTAEGIQLYSFV----TYYVEDLKVNWSHNGSAIRYSDRVKTG 1508
             +V  +    +   K++ T  G+   S V     Y    + V+W H G+ I    + +T 
Sbjct: 7674 -QVSDRTVPPSFTRKLKET-NGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTT 7731

Query: 1509 VTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAE 1568
            +T     L +N    +D G Y               +++G   DE  A     +  +  +
Sbjct: 7732 LTDNTCALTVNMLEESDSGDYTCI----------ATNMAGS--DECSAPLTVREPPSFVQ 7779

Query: 1569 KNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRT 1628
            K         PD + +  G  +  T  V G PP  VSW K    L   D CN+  E    
Sbjct: 7780 K---------PDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLE-DSV 7829

Query: 1629 AYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGK 1682
            A   +  V T+ SG+Y  +V N+ G  +    + +  P +  +     S++ GK
Sbjct: 7830 AELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGK 7883



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 115/512 (22%), Positives = 199/512 (38%), Gaps = 49/512 (9%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            FEC+   P     W KD    + + R++++ +    ++      M D G Y+  V     
Sbjct: 3077 FECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYT--VVAGGN 3134

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQ--VRFWMQAEKLSGNAKV 1275
            ++++ L  E    R+ ++  E             V+++EK +  V F +  + +  +   
Sbjct: 3135 VSTAKLFVEGRDVRIRSIKKE-------------VQVIEKQRAVVEFEVNEDDVDAHWYK 3181

Query: 1276 NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVG 1335
            + I    ++ E  KY   ++R   I  MF+ + +  D G YTF        N S+V L  
Sbjct: 3182 DGIEINFQVQERHKYV--VERR--IHRMFISETRQSDAGEYTFVA----GRNRSSVTLYV 3233

Query: 1336 DVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDE 1395
            +  +  Q   E Q       +   F                 C V + + +  I WYK+E
Sbjct: 3234 NAPEPPQVLQELQPVTVQSGKPARF-----------------CAVISGRPQPKISWYKEE 3276

Query: 1396 REISVDEKHDF-KDGI-CTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1453
            + +S   K  F  DG   TLL+ E   +DA +Y    K+D G   +   L  E  + +  
Sbjct: 3277 QLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSP 3336

Query: 1454 EVCKKIALSA--TDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTG 1511
            +    +   A  T L+   T+EG            DLKV+W      I+ S   +     
Sbjct: 3337 DQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFE 3396

Query: 1512 EQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR 1571
            +   L+I E  P D+G Y     +       T +LS +A +    E  R++Q    E   
Sbjct: 3397 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHE--RIEQEIEMEMKA 3454

Query: 1572 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYF 1631
            A V+    + + +  G     TC +   P     W K  + +   D C+++  +   +  
Sbjct: 3455 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR-SSKYISSL 3513

Query: 1632 TINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
             I      D G+Y     N+YGS +   T++V
Sbjct: 3514 EILRTQVVDCGEYTCKASNEYGSVSCTATLTV 3545



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 121/565 (21%), Positives = 222/565 (39%), Gaps = 93/565 (16%)

Query: 1132 PVVAETRPGTKEVVVNVDDDGVISLNFECDKM-TPKSEFSWSKDYVSTEDSPRLEVESKG 1190
            P V  + P   E + N +      ++ EC+   TP  E  W KD      S + ++ SK 
Sbjct: 5516 PPVFSSFPPIVETLKNAE------VSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKN 5569

Query: 1191 NKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTV----PV 1246
              T +   ++   D+G Y C   +  G  S   +   +LK       +    TV    P 
Sbjct: 5570 FHTSIHILNVDTSDIGEYHCKAQNEVG--SDTCVCTVKLKEPPRFVSKLNSLTVVAGEPA 5627

Query: 1247 KSELAVEILEKGQVRFWMQAEKL---SGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEM 1303
            + + ++E  +   V++  + E++   S N ++ ++ N                   +  +
Sbjct: 5628 ELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVEN-------------------VATL 5668

Query: 1304 FMEKLQDEDEGTYTFQLQD--GKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFV 1361
               K +  + G Y  Q+++  G   N +T++++             +    + K GP  V
Sbjct: 5669 QFAKAEPANAGKYICQIKNDGGMRENMATLMVL-------------EPAVIVEKAGPMTV 5715

Query: 1362 EYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFK--DGICTLLITEFS 1419
                    GE    L+CKVA    E  + WYKD + ++  +KH F   + I +L I    
Sbjct: 5716 ------TVGE-TCTLECKVAGTP-ELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVE 5767

Query: 1420 KKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYS 1479
            ++DAG Y   ++++ GK  S   +VD + + +     +++  +   L      E     S
Sbjct: 5768 RQDAGTYTFQVQNNVGKS-SCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGS 5826

Query: 1480 FVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTG 1539
                    + V W H  + I    + +T  +     LQ+N    +D G Y          
Sbjct: 5827 ------SPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCV------- 5873

Query: 1540 HQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGD 1599
                 +++G   DE  A     +  +  ++         P+ + +  GK +  T  + G 
Sbjct: 5874 ---AANVAGS--DECRAVLTVQEPPSFVKE---------PEPLEVLPGKNVTFTSVIRGT 5919

Query: 1600 PPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDF 1659
            PP +V+W +  + L   D CN+ FE    A   +  +  + SG+Y  VV N  G   +  
Sbjct: 5920 PPFKVNWFRGARELVKGDRCNIYFE-DTVAELELFNIDISQSGEYTCVVSNNAGQ--ASC 5976

Query: 1660 TVSVFIPEEEARMAAL--ESLKGGK 1682
            T  +F+ E  A +  L   S++ GK
Sbjct: 5977 TTRLFVKEPAAFLKRLSDHSVEPGK 6001



 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 131/602 (21%), Positives = 222/602 (36%), Gaps = 83/602 (13%)

Query: 1065 SGRTPVT-GYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGV 1123
            +G  P++  +F D +E  A E      ++      +L++  L+   S  +   A N+AG 
Sbjct: 4699 AGSHPISIQWFKDDQEISASEKYKFSFHD---NTAFLEISQLEGTDSGTYTCSATNKAGH 4755

Query: 1124 GKPSD---LAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTED 1180
             + S    +  P     +P +++V  N      + L        P +   W KD      
Sbjct: 4756 NQCSGHLTVKEPPYFVEKPQSQDVNPNTR----VQLKALVGGTAPMT-IKWFKDNKELHS 4810

Query: 1181 SPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHK 1240
                 V      T +        D G Y C +++  G A+S        K  L +    +
Sbjct: 4811 GAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATS--------KATLFVKEPPQ 4862

Query: 1241 FPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMH-IDRNTG 1299
            F    +K    V +L  GQ   +      +   +V++  +  EI    K+ +  ID   G
Sbjct: 4863 F----IKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFID---G 4915

Query: 1300 IIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPH 1359
            +    +   + E+ GTY  + ++   T   ++ L                     K+ P 
Sbjct: 4916 LATFQISGARVENSGTYVCEARNDAGTASCSIELKV-------------------KEPPT 4956

Query: 1360 FVEYLS-WEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKD--GICTLLIT 1416
            F+  L   EV    +V L+C+V        + W K+ REI   +K+   D   +  L IT
Sbjct: 4957 FIRELKPVEVVKYSDVELECEVTGTPP-FEVTWLKNNREIRSSKKYTLTDRVSVFNLHIT 5015

Query: 1417 EFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQ 1476
            +    D G Y+ I+ ++ G      ++   A KE    + KKI  + T LK  +T +   
Sbjct: 5016 KCDPSDTGEYQCIVSNEGGSCSCSTRV---ALKEPPSFI-KKIENTTTVLKSSATFQSTV 5071

Query: 1477 LYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDG 1536
              S        + + W  +   +   D V          LQI        G+Y  +    
Sbjct: 5072 AGS------PPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQA--- 5122

Query: 1537 KTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNV 1596
                      +    +  YA     + A I EK ++         V + E   + L C V
Sbjct: 5123 ---------KNESGVERCYAFLLVQEPAQIVEKAKS---------VDVTEKDPMTLECVV 5164

Query: 1597 WGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSET 1656
             G P  +V WLK+ K +    + ++ FE    A F I  V   DSG+Y   V+N +GS +
Sbjct: 5165 AGTPELKVKWLKDGKQIVPSRYFSMSFE-NNVASFRIQSVMKQDSGQYTFKVENDFGSSS 5223

Query: 1657 SD 1658
             D
Sbjct: 5224 CD 5225



 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 112/536 (20%), Positives = 205/536 (38%), Gaps = 86/536 (16%)

Query: 1144 VVVNVDDDGVISLNFECDKM-TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGM 1202
            V V+V D    S + +C    TP+   SW K       +   ++  + N   + F  + +
Sbjct: 7970 VKVSVGD----SASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDI 8025

Query: 1203 DDLGIYSCDVTDTDG--IASSYL-IDEEELKRLLALSHEHKFPTV--PVKSELAVEILEK 1257
            +D G Y C   ++ G   AS++L + E++L    +        TV  PV  + A+   E 
Sbjct: 8026 NDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEP 8085

Query: 1258 GQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
              V ++   + L  +  V   F +               NT  + +F        + + T
Sbjct: 8086 ISVSWYKDGKPLKDSPNVQTSFLD---------------NTATLNIFKTDRSLAGQYSCT 8130

Query: 1318 FQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSW--EVTGECNVL 1375
                 G A++ + ++L                     K  P F   L+    V GE +  
Sbjct: 8131 ATNPIGSASSSARLILTEG------------------KNPPFFDIRLAPVDAVVGE-SAD 8171

Query: 1376 LKCKVANIKKETHIVWYKDEREISVDEKHD--FKDGICTLLITEFSKKDAGIYEVILKDD 1433
             +C V   +    + W KD REI    K+   + +    L + +  K D+G Y     ++
Sbjct: 8172 FECHVTGTQP-IKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNE 8230

Query: 1434 RGKDKS------RLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVED 1487
             GKD        + +L+  +F + + E  ++        K++    G Q           
Sbjct: 8231 VGKDSCTAQLNIKERLIPPSFTKRLSETVEET--EGNSFKLEGRVAGSQ----------P 8278

Query: 1488 LKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLS 1547
            + V W  N   I+ +   +       + LQ+ +   ND G Y  ++ +           +
Sbjct: 8279 ITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSND----------A 8328

Query: 1548 GQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWL 1607
            G A   +    +  K+  + +++   V        T+ EG+ + L+C+V G  P  + WL
Sbjct: 8329 GSALCTSSIVIKEPKKPPVFDQHLTPV--------TVSEGEYVQLSCHVQGSEPIRIQWL 8380

Query: 1608 KNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
            K  + +   D C+  F +G TA   +  V+ ADSG Y     N  GS+T+   V++
Sbjct: 8381 KAGREIKPSDRCSFSFASG-TAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTI 8435



 Score = 78.6 bits (192), Expect = 5e-14
 Identities = 110/511 (21%), Positives = 199/511 (38%), Gaps = 76/511 (14%)

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            +P+ +  W KD    ++S +  +    +   +   +L ++D G Y+C+  +  G ASS  
Sbjct: 7332 SPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASS-- 7389

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
                      + S + K P +  K    +E L+   V    + +  +    V++  +++E
Sbjct: 7390 ----------STSLKVKEPPIFRKKPHPIETLKGADVHLECELQG-TPPFHVSWYKDKRE 7438

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNH-STVVLVGDVFKKLQ 1342
            +  G KYK  I     +  + +  +   D G Y       KATN   +   VG +     
Sbjct: 7439 LRSGKKYK--IMSENFLTSIHILNVDAADIGEY-----QCKATNDVGSDTCVGSI----- 7486

Query: 1343 KEAEFQRQEWIRKQGPHFVEYLS--WEVTGECNVLLKCKVANIKKETHIVWYKDEREISV 1400
                        K  P FV+ LS    V G+  V L+  +    +   +VW+KD+ EI  
Sbjct: 7487 ----------ALKAPPRFVKKLSDISTVVGK-EVQLQTTIEG-AEPISVVWFKDKGEIVR 7534

Query: 1401 DEKH---DFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCK 1457
            +  +    + + I TL  +     +AG Y   +K+D G        + E F  L +    
Sbjct: 7535 ESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAG--------MQECFATLSVLEPA 7586

Query: 1458 KIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQ 1517
             I      +K+ +T +   L   V     +L   W  +G  +   ++ K     +   L+
Sbjct: 7587 TIVEKPESIKV-TTGDTCTLECTVA-GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLK 7644

Query: 1518 INEPTPNDKGKYVMELFD--GKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVL 1575
            I    P+D G Y  E+ +  GK     ++ +S +    ++   ++LK+            
Sbjct: 7645 IINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFT--RKLKET----------- 7691

Query: 1576 GGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTING 1635
             GL        G ++ + C V+G PP  VSW      ++S            T   T+N 
Sbjct: 7692 NGL-------SGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTL-TDNTCALTVNM 7743

Query: 1636 VSTADSGKYGLVVKNKYGSETSDFTVSVFIP 1666
            +  +DSG Y  +  N  GS+     ++V  P
Sbjct: 7744 LEESDSGDYTCIATNMAGSDECSAPLTVREP 7774



 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 58/224 (25%), Positives = 109/224 (48%), Gaps = 17/224 (7%)

Query: 157   ERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTA 216
             E +K++AA   +++++  E  IT + Q++   +T A  ++ +++ S    Q    + + A
Sbjct: 33006 EEVKKSAATSLEKSIVHEE--ITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIA 33063

Query: 217   SRQSVV----SKQATSALQQEETSEKKSRKVVIREKAER-----LSLRKTLEETET--YH 265
                 V       + T++ +         + + I++ + R       + KT E      Y 
Sbjct: 33064 GATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYD 33123

Query: 266   AKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGK 325
               L+++ L  AP FI +PRS  + E +NV   C I+G P P + W+KN +PI++ +N   
Sbjct: 33124 LTLSKE-LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVS- 33181

Query: 326   YIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
               I     +++LEI      D+ +Y   A N +G+ SA AS++V
Sbjct: 33182 --ISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 110/529 (20%), Positives = 204/529 (38%), Gaps = 79/529 (14%)

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGI----A 1219
            TP  E  W KD  +   SP   +    NK  +   +L + D G+YSC  ++  G     A
Sbjct: 3577 TPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQA 3636

Query: 1220 SSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIF 1279
               +ID+    + L           PV+S +  ++  + QV    +  K++    V +  
Sbjct: 3637 ELIIIDKPHFIKELE----------PVQSAINKKVHLECQVD---EDRKVT----VTWSK 3679

Query: 1280 NEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFK 1339
            + +++  G  YK+  +     +E+ + KL+D      T   + G ++  +TV +      
Sbjct: 3680 DGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV------ 3733

Query: 1340 KLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREIS 1399
                    +   +++K  P ++      + GE +  L CK+        + W+K+ +E+S
Sbjct: 3734 -------REPPSFVKKVDPSYL-----MLPGE-SARLHCKLKG-SPVIQVTWFKNNKELS 3779

Query: 1400 VDE--KHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCK 1457
                 +  F +    L IT+   +D+G Y     +D G D    ++V +     +  +  
Sbjct: 3780 ESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEP 3839

Query: 1458 KIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQ 1517
               +  T+  +Q    G              +++W  +   IR S + +       + L+
Sbjct: 3840 ADIVRGTNALLQCEVSG----------TGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLE 3889

Query: 1518 INEPTPNDKGKY--VMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVL 1575
            I      D G+Y  V+    GK G   T                 LK+     K      
Sbjct: 3890 IFSFNSADVGEYECVVANEVGKCGCMAT---------------HLLKEPPTFVKK----- 3929

Query: 1576 GGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTING 1635
              + D++ +  G+ + L   V G  P  V+W+K ++ +  D    + F  G  A   I  
Sbjct: 3930 --VDDLIAL-GGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNG-VAVLIIPD 3985

Query: 1636 VSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGKKA 1684
            V  +  GKY  + +N+ GS+TS   + V  P +    A L  +  G  A
Sbjct: 3986 VQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPA 4034



 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 114/537 (21%), Positives = 192/537 (35%), Gaps = 87/537 (16%)

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS-- 1221
            TP+   SW K++     +P  +++ K N   +    +   D+G YSC   ++ G  +S  
Sbjct: 7046 TPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSA 7105

Query: 1222 -YLIDEEELKRLLA--LSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYI 1278
              +I   +L    A  L   H+    PV  E  +   E  QV ++     L  +A +   
Sbjct: 7106 VLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTS 7165

Query: 1279 FNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVF 1338
            F            +H      I++     +     G Y     +   T  S+  L+    
Sbjct: 7166 F------------VHNVATLQILQTDQSHI-----GQYNCSASNPLGTASSSAKLILS-- 7206

Query: 1339 KKLQKEAEFQRQEWIRKQGPHFVEYLSWEVT---GECNVLLKCKVANIKKETHIVWYKDE 1395
                             + P F +     V    GE     KC V        I W KD 
Sbjct: 7207 ---------------EHEVPPFFDLKPVSVDLALGESGTF-KCHVTGTAP-IKITWAKDN 7249

Query: 1396 REISV--DEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL-VDEA---FK 1449
            REI    + K    +   TL + +  K DAG Y     +  GKD    +L V E     K
Sbjct: 7250 REIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIK 7309

Query: 1450 ELM-MEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTG 1508
            +L    + K+   +  + KI  + E              +KV W  + + I+ S + +  
Sbjct: 7310 KLEPSRIVKQDEFTRYECKIGGSPE--------------IKVLWYKDETEIQESSKFRMS 7355

Query: 1509 VTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAE 1568
                   L+++  +  D G Y  E  +       +  L             ++K+  I  
Sbjct: 7356 FVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSL-------------KVKEPPIFR 7402

Query: 1569 KNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRT 1628
            K         P  +   +G  ++L C + G PP  VSW K+++ L S     +  E   T
Sbjct: 7403 KK--------PHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLT 7454

Query: 1629 AYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGKKAK 1685
            +   +N V  AD G+Y     N  GS+T   ++++  P    +  +  S   GK+ +
Sbjct: 7455 SIHILN-VDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQ 7510



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 104/533 (19%), Positives = 203/533 (38%), Gaps = 97/533 (18%)

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             F C+  T  ++  W ++  +  DS +  +  K     +  +D  +DD   Y+  +T+  G
Sbjct: 12659 FNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 12718

Query: 1218  ----IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
                  A++ +++EE+L+ +            P+K    +E +EK  V FW +  +L  N 
Sbjct: 12719 ENVKSAANLIVEEEDLRIV-----------EPLKD---IETMEKKSVTFWCKVNRL--NV 12762

Query: 1274  KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1333
              + +  N +E+    +    +D+   ++ +  +     DEG Y       K+     ++ 
Sbjct: 12763 TLKWTKNGEEVPFDNRVSYRVDKYKHMLTI--KDCGFPDEGEYIVTAGQDKSVAELLII- 12819

Query: 1334  VGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECN-VLLKCKVANIKKETHIVWY 1392
                                  +    FVE+L  +   E +  +  C+++  +++ ++ WY
Sbjct: 12820 ---------------------EAPTEFVEHLEDQTVTEFDDAVFSCQLS--REKANVKWY 12856

Query: 1393  KDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKE-- 1450
             ++ REI   +K+ F+             KD  I+ +I+KD R  D+       E  K   
Sbjct: 12857 RNGREIKEGKKYKFE-------------KDGSIHRLIIKDCRLDDECEYACGVEDRKSRA 12903

Query: 1451  --LMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTG 1508
                + E+  +I     D+     A G  +        + ++V W  N   +   D+ +  
Sbjct: 12904 RLFVEEIPVEIIRPPQDIL---EAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMM 12960

Query: 1509  VTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAE 1568
               G+   LQI +  P D+G+Y     D                 EA A+ +      I  
Sbjct: 12961 SEGKIHRLQICDIKPRDQGEYRFIAKD----------------KEARAKLELAAAPKIKT 13004

Query: 1569  KNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRT 1628
              ++  V         +  GK L +       P  E  W K  + L++     +   A +T
Sbjct: 13005 ADQDLV---------VDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK---TIDTTAEQT 13052

Query: 1629  AYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVF-IPEEEARMAALESLKG 1680
             + F I      D G+Y +V++NK+G       + V  +P     +   E+  G
Sbjct: 13053 S-FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 13104



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 88/403 (21%), Positives = 162/403 (40%), Gaps = 63/403 (15%)

Query: 1268 KLSGNA--KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQ-LQDGK 1324
            KL G+   +V +  N KE+ E    +M+   +  I+++   K+  ED G+Y+ + + D  
Sbjct: 3760 KLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKV--EDSGSYSCEAVNDVG 3817

Query: 1325 ATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLS-WEVTGECNVLLKCKVANI 1383
            + + ST +++                    K+ P F++ L   ++    N LL+C+V+  
Sbjct: 3818 SDSCSTEIVI--------------------KEPPSFIKTLEPADIVRGTNALLQCEVSGT 3857

Query: 1384 KKETHIVWYKDEREISVDEKHDF---KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSR 1440
                 I W+KD+++I   +K+     K  +C L I  F+  D G YE ++ ++ GK    
Sbjct: 3858 GP-FEISWFKDKKQIRSSKKYRLFSQKSLVC-LEIFSFNSADVGEYECVVANEVGKCGCM 3915

Query: 1441 LKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIR 1500
               + +     + +V   IAL    + +Q+   G           E + V W      IR
Sbjct: 3916 ATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGS----------EPISVTWMKGQEVIR 3965

Query: 1501 YSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR 1560
               ++K   +     L I +   +  GKY   L + + G Q +V            E   
Sbjct: 3966 EDGKIKMSFSNGVAVLIIPDVQISFGGKYTC-LAENEAGSQTSV-----------GELIV 4013

Query: 1561 LKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCN 1620
             + A I E+          +++ +  G    L   V G P  +  W K+ + L +     
Sbjct: 4014 KEPAKIIER---------AELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYR 4064

Query: 1621 LKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
            + F+    A          DSG+Y   + N+ GS + + T +V
Sbjct: 4065 ISFK-NNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTV 4106



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 116/505 (22%), Positives = 186/505 (36%), Gaps = 60/505 (11%)

Query: 1170 SWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEEL 1229
            SW KD    +DSP ++     N   +          G YSC  T+  G ASS        
Sbjct: 8089 SWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASS-------- 8140

Query: 1230 KRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPK 1289
               L L+     P   ++  LA      G+   +      +   KV++  + +EI  G K
Sbjct: 8141 SARLILTEGKNPPFFDIR--LAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGK 8198

Query: 1290 YKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQR 1349
            Y++    N+  + +   K+   D G YT    +    +  T              A+   
Sbjct: 8199 YQISYLENSAHLTVL--KVDKGDSGQYTCYAVNEVGKDSCT--------------AQLNI 8242

Query: 1350 QEWIRKQGPHFVEYLSWEV--TGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHD-- 1405
            +E  R   P F + LS  V  T   +  L+ +VA  +  T + WYK+  EI      +  
Sbjct: 8243 KE--RLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPIT-VAWYKNNIEIQPTSNCEIT 8299

Query: 1406 FKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATD 1465
            FK+    L + +    DAG+Y   + +D G       +V        ++  KK  +    
Sbjct: 8300 FKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIV--------IKEPKKPPVFDQH 8351

Query: 1466 LKIQSTAEG--IQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTP 1523
            L   + +EG  +QL   V    E +++ W   G  I+ SDR           L++ +   
Sbjct: 8352 LTPVTVSEGEYVQLSCHVQGS-EPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAK 8410

Query: 1524 NDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGL----- 1578
             D G YV           K  +++G    ++    +     A A K +A V G L     
Sbjct: 8411 ADSGDYVC----------KASNVAGSDTTKSKVTIKDKPAVAPATK-KAAVDGRLFFVSE 8459

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
            P  + + E         V GDP P V W K +    +        + G  A   I   + 
Sbjct: 8460 PQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTK 8519

Query: 1639 ADSGKYGLVVKNKYGSETSDFTVSV 1663
             DSG Y  V  N++G   S+  + V
Sbjct: 8520 TDSGLYRCVAFNEHGEIESNVNLQV 8544



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 110/519 (21%), Positives = 189/519 (36%), Gaps = 92/519 (17%)

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG--IASS 1221
            TP  E  W KD     +S + ++ SK   T +   +L   D+G Y C  T+  G    S 
Sbjct: 6484 TPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSC 6543

Query: 1222 YLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAE----KLSGNAKVNY 1277
             +  +E  + +  LS         V+    VE  +   V  W++      + S N ++++
Sbjct: 6544 SVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISV-VWLKDRGEVIRESENTRISF 6602

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDV 1337
            I N                   I  + +   +  + G Y  Q+++       + VL    
Sbjct: 6603 IDN-------------------IATLQLGSPEASNSGKYICQIKNDAGMRECSAVLT--- 6640

Query: 1338 FKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDERE 1397
                      +    I K  P  V       TG     L+C V     E    W+KD RE
Sbjct: 6641 --------VLEPARIIEKPEPMTV------TTGN-PFALECVVTGTP-ELSAKWFKDGRE 6684

Query: 1398 ISVDEKHD--FKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRL------KLVDEAFK 1449
            +S D KH   F + + +L I      D G+Y   +K+  GK    +      ++V  +F 
Sbjct: 6685 LSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFI 6744

Query: 1450 ELMMEVCKKIALSAT-DLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTG 1508
              + +V   +  S   + ++  +A               + V W  +G+ I    + ++ 
Sbjct: 6745 RKLKDVNAILGASVVLECRVSGSAP--------------ISVGWFQDGNEIVSGPKCQSS 6790

Query: 1509 VTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAE 1568
             +     L ++   P+D G Y               +++G   DE  A     +  +  +
Sbjct: 6791 FSENVCTLNLSLLEPSDTGIYTCV----------AANVAGS--DECSAVLTVQEPPSFEQ 6838

Query: 1569 KNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRT 1628
                      PD V +  G +L  T  + G PP +V W K  + L   + CN+  E   T
Sbjct: 6839 T---------PDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVT 6889

Query: 1629 AYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPE 1667
                +  V   +SG Y  +V N  GS  +  T  +F+ E
Sbjct: 6890 E-LELFEVQPLESGDYSCLVTNDAGS--ASCTTHLFVKE 6925



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 86/395 (21%), Positives = 145/395 (36%), Gaps = 50/395 (12%)

Query: 1275 VNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLV 1334
            V++   + ++   P+Y+ +   N  +  +   K+   D G YT + ++   T  S  V  
Sbjct: 6110 VSWYKGDTKLRPTPEYRTYFTNN--VATLVFNKVNINDSGEYTCKAENSIGTASSKTV-- 6165

Query: 1335 GDVFKKLQKEAEFQRQEWIRKQGPHFVEYLS-WEVTGECNVLLKCKVANIKKETHIVWYK 1393
                        F+ QE  R+  P F   L   E T    V L C++ N      + WY+
Sbjct: 6166 ------------FRIQE--RQLPPSFARQLKDIEQTVGLPVTLTCRL-NGSAPIQVCWYR 6210

Query: 1394 DEREISVDE--KHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKEL 1451
            D   +  DE  +  F D + TL I +     +G Y     +  G   S  +L     K+ 
Sbjct: 6211 DGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKS 6270

Query: 1452 MMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTG 1511
                 K +++           E       VT   + +++ WS +   IR          G
Sbjct: 6271 PFFDIKPVSIDVI------AGESADFECHVTG-AQPMRITWSKDNKEIRPGGNYTITCVG 6323

Query: 1512 EQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR 1571
                L+I +    D G+Y           Q T D+            + +  A ++ K  
Sbjct: 6324 NTPHLRILKVGKGDSGQYTC---------QATNDVG-----------KDMCSAQLSVKEP 6363

Query: 1572 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYF 1631
             + +  L      ++G+++ L C + G P  +VSW +N+  L      N+ F     A  
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF-INSVALL 6422

Query: 1632 TINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIP 1666
            TIN  S  DSG Y     N  G  +    ++V  P
Sbjct: 6423 TINEASAEDSGDYICEAHNGVGDASCSTALTVKAP 6457



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 67/296 (22%), Positives = 117/296 (39%), Gaps = 27/296 (9%)

Query: 1378  CKVANIKKETHIVWYKDEREISVDEKHD--FKDGICTLLITEFSKKDAGIYEVILKDDRG 1435
             CK+ N  + T + WY   R++   EK++  ++DG+  L + + +K D G Y   + +D G
Sbjct: 31589 CKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYG 31648

Query: 1436  KDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHN 1495
             +D S  +L  +  +E+    C++     T  KI+   + ++L      +   L    ++ 
Sbjct: 31649 EDSSYAELFVKGVREVYDYYCRR-----TMKKIKRRTDTMRLLERPPEFTLPLYNKTAYV 31703

Query: 1496  GSAIRYSDRVKTGVTGEQIWLQINE---PTPNDKGKYVMELFDGKTGHQKTVDLSGQAYD 1552
             G  +R+   +         W +  +   P  NDK KY  E    K  +Q T++      D
Sbjct: 31704 GENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDK-KYTFE--SDKGLYQLTINSVTTDDD 31760

Query: 1553  EAYAEFQRLKQAAIAEKNRARVLGGLPDV--------------VTIQEGKALNLTCNVWG 1598
               Y    R K    + K +  V    P                   QEG+++     V G
Sbjct: 31761 AEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 31820

Query: 1599  DPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGS 1654
              PPP + W K+ + L+   +  +  E        I      D+G Y +   N  GS
Sbjct: 31821 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGS 31876



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 102/489 (20%), Positives = 180/489 (36%), Gaps = 79/489 (16%)

Query: 1165 PKSEFSWSKDYVSTEDSPRLE-VESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            P  E  W K+ V  E S R+     + N  ++  +D+  +D         +  G  SS+ 
Sbjct: 2105 PDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHA 2164

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
                + K+L+  + E +      K  +A             + E      KV +  +  E
Sbjct: 2165 FLLVQAKQLITFTQELQDVVAKEKDTMAT-----------FECETSEPFVKVKWYKDGME 2213

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQK 1343
            + EG KY+MH DR    + +      D ++ +    ++D      + +++ G V + +++
Sbjct: 2214 VHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVL-VEDENVKTTAKLIVEGAVVEFVKE 2272

Query: 1344 EAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVA--NIKKETHIVWYKDEREISVD 1401
              + +  E                 +GE    L+C V+  NI+ +    WY ++ E+  +
Sbjct: 2273 LQDIEVPE---------------SYSGE----LECIVSPENIEGK----WYHNDVELKSN 2309

Query: 1402 EKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKI 1459
             K+    + G   L + + +K+D G Y  ++  D  K   +LK+       L        
Sbjct: 2310 GKYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTCKLKMKPRPIAILQ------- 2360

Query: 1460 ALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN 1519
                  L  Q   EG  +   V   +E ++  W  +G  ++ SDRV   +  +   L I 
Sbjct: 2361 -----GLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIE 2415

Query: 1520 EPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLP 1579
            + T  D G Y   +          + LS       Y+                 V+  L 
Sbjct: 2416 DMTKEDAGNYSFTI--------PALGLSTSGRVSVYS---------------VDVITPLK 2452

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
            DV  I+  KA+ L C V       V W  N++ +  DD        G      IN    +
Sbjct: 2453 DVNVIEGTKAV-LECKVSVPDVTSVKWYLNDEQIKPDDRVQ-AIVKGTKQRLVINRTHAS 2510

Query: 1640 DSGKYGLVV 1648
            D G Y L+V
Sbjct: 2511 DEGPYKLIV 2519



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 121/559 (21%), Positives = 206/559 (36%), Gaps = 117/559 (20%)

Query: 1168  EFSWSKDYVSTEDSPRLEVESKGNKT-KMTFKDLGMDDLGIYSCDVTDTDGIASSYL--- 1223
             E +W KD    +++   +     + T ++   +L   D G Y C+++   G + + L   
Sbjct: 32748 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 32807

Query: 1224  -------------------IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWM 1264
                                 D++  +  +    E K P       + V  L+   V    
Sbjct: 32808 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDS 32867

Query: 1265  QAE---KLSGNAKVNYIFNE--KEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQ 1319
              A+   K +G  +   I+ +  K I +G KYK+  D+    +E+   K    D G YT  
Sbjct: 32868 VAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEI--HKTDTSDSGLYTCT 32925

Query: 1320  LQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCK 1379
             +++   +  S+  L      K  K+ E Q+              +S + T E   +   K
Sbjct: 32926 VKNSAGSVSSSCKLT----IKAIKDTEAQK--------------VSTQKTSE---ITPQK 32964

Query: 1380  VANIKKETHIVWYKDER----EISVDEKHDFKDGICTLLITEFSKKDAG-------IYEV 1428
              A +++E      + E     E    EK   K+    +LI+E  KK A        ++E 
Sbjct: 32965 KAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEE 33024

Query: 1429  ILKDDRGKDKSRLKLVDEAFKELMME------VCKKIALSATDLKIQSTAEGIQLYSFVT 1482
             I K  +  ++ R     +AF   M        V K     ATD+K               
Sbjct: 33025 ITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVK--------------- 33069

Query: 1483  YYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKG--KYVMELFDGKTGH 1540
                      W  NG  +  S+  + GV+G    L I + +  D+G    + +  +G    
Sbjct: 33070 ---------WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKC 33120

Query: 1541  QKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDP 1600
             Q  + LS +  D           A I++          P    I EG+ +  TC + G+P
Sbjct: 33121 QYDLTLSKELSDAP---------AFISQ----------PRSQNINEGQNVLFTCEISGEP 33161

Query: 1601  PPEVSWLKNEKALASDDHCNLKFEAGRTAY-FTINGVSTADSGKYGLVVKNKYGSETSDF 1659
              PE+ W KN   ++     N+     R  Y   I   S +DSGKY +  KN  G  ++  
Sbjct: 33162 SPEIEWFKNNLPISISS--NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 33219

Query: 1660  TVSVF-IPEEEARMAALES 1677
             ++ V  + EE +R   L +
Sbjct: 33220 SLMVLPLVEEPSREVVLRT 33238



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 91/360 (25%), Positives = 148/360 (41%), Gaps = 39/360 (10%)

Query: 175  EEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEE 234
            E  I  S  +T  K+ +A+  S+A K + + K  T     T  R               +
Sbjct: 831  EASIAGSAIATLQKELSAT--SSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTPD 888

Query: 235  TSEKKSRKVVIREKAERLSLRKTLEET-ETYH---AKLNEDHLLHAP-EFIIKP------ 283
            T + ++   V +E    ++     EE  E  H   AK+ E   + AP E  + P      
Sbjct: 889  TYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSG 948

Query: 284  -RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGC 342
             ++ TV E E+V L C I+G+P P VTWY+    I    +   + I  + G+  L I   
Sbjct: 949  LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSID---FQITFQSGIARLMIREA 1005

Query: 343  DFEDTAQYRASAMNVKGEL--SAYASVVVKR----------YKGEFDETRFHAGASTMPL 390
              ED+ ++  SA+N  G +  S Y +V V             K   +E RF      +  
Sbjct: 1006 FAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMT 1065

Query: 391  SFGVT--PYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGV 448
               +T    G       +F  K  V    EG ++  GC+V   P     +P + W ++GV
Sbjct: 1066 DTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP-----KPHVYWKKSGV 1120

Query: 449  PLSPSKWVQTLWSGE--RATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEI 506
            PL+     +  ++ +     L  S    +D G YTI VR  ++ E  ++   + +AD E+
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVR-NKHGETSASASLLEEADYEL 1179



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 63/303 (20%), Positives = 130/303 (42%), Gaps = 23/303 (7%)

Query: 1039  PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1098
             P  P +L   EV+KDS+ L W+PP+  G   +T Y V+ +E   K   +  +     K  
Sbjct: 25199 PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK--AYATITNNCTKTT 25256

Query: 1099  YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD-DDGVISLN 1157
             + ++  L+EG SY FRV A N+ G+G P++   PV     P     V  VD      ++ 
Sbjct: 25257 F-RIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIK 25315

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             +E  +    S+ +     + T+ S +    ++    + T   L   +  ++     +  G
Sbjct: 25316 WEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKG 25375

Query: 1218  IASSYLIDEEELKRLLALSHEHKFP----TVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
              +    +    + R + +    + P     V  + +L +++  KG+ +           A
Sbjct: 25376 RSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQ-----------A 25424

Query: 1274  KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD--GKATNHSTV 1331
              VN+  + + + E    ++++  +  +  + +++   ED GTY   + +  G  T   T+
Sbjct: 25425 TVNWRKDGQTLKE--TTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITI 25482

Query: 1332  VLV 1334
             +++
Sbjct: 25483 IVL 25485



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 62/233 (26%), Positives = 93/233 (39%), Gaps = 35/233 (15%)

Query: 251   RLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTW 310
             R +++K    T+T         L   PEF +   + T +  ENV+   +I   PEP VTW
Sbjct: 31670 RRTMKKIKRRTDTMRL------LERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTW 31723

Query: 311   YKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
             YK+   I    N  KY  ES  G++ L IN    +D A+Y   A N  GE S  A + V 
Sbjct: 31724 YKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 31783

Query: 371   RYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVI 430
              +    D T         P+                F      +  +EG+++    RV  
Sbjct: 31784 LHPPPTDST-------LRPM----------------FKRLLANAECQEGQSVCFEIRVSG 31820

Query: 431   TPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG-ERATLTFSHLNKEDEGLYTI 482
              P      P ++W ++G PLS    ++ +  G +   L       ED G Y +
Sbjct: 31821 IP-----PPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 31868



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 110/549 (20%), Positives = 203/549 (36%), Gaps = 91/549 (16%)

Query: 1132  PVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGN 1191
             P V  T+P   + V    ++G  ++  EC+     ++  W K+      S + E+ + G 
Sbjct: 12283 PPVEFTKPLEDQTV----EEGATAV-LECEVSRENAKVKWFKNGTEILKSKKYEIVADGR 12337

Query: 1192  KTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELA 1251
               K+   D   +D+  Y+CD  D     +  ++                 P V     L 
Sbjct: 12338 VRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVP----------------PHVEFLRPLT 12381

Query: 1252  -VEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQD 1310
              +++ EK   RF  + E    NAKV +  +  EI +G KY   I     +  + + K   
Sbjct: 12382 DLQVREKEMARF--ECELSRENAKVKWFKDGAEIKKGKKY--DIISKGAVRILVINKCLL 12437

Query: 1311  EDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTG 1370
             +DE  Y+ +++  + +   TV         L++EA F +               + EV+ 
Sbjct: 12438 DDEAEYSCEVRTARTSGMLTV---------LEEEAVFTK------------NLANIEVSE 12476

Query: 1371  ECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVIL 1430
                + L C+V+  K    ++WYK + EI    +++        ++TE  K+   I    L
Sbjct: 12477 TDTIKLVCEVS--KPGAEVIWYKGDEEIIETGRYE--------ILTEGRKRILVIQNAHL 12526

Query: 1431  KDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKV 1490
              +D G    RL       K  + E+  +      +L+I    EG +     +   E   V
Sbjct: 12527 -EDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEI---LEGEKAEFVCSISKESFPV 12582

Query: 1491  NWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQA 1550
              W  +   +   D+      G++  L + + T  D G YV+ +   +     TV      
Sbjct: 12583 QWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTV------ 12636

Query: 1551  YDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNE 1610
                                 + R++  L D   ++E + +   C V      +  W +NE
Sbjct: 12637 ------------------IEKLRIVVPLKD-TRVKEQQEVVFNCEV-NTEGAKAKWFRNE 12676

Query: 1611  KALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEA 1670
             +A+  D    +  +        I      D   Y + + N  G E      ++ + EE+ 
Sbjct: 12677 EAI-FDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG-ENVKSAANLIVEEEDL 12734

Query: 1671  RMAALESLK 1679
             R+  +E LK
Sbjct: 12735 RI--VEPLK 12741



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 121/586 (20%), Positives = 216/586 (36%), Gaps = 86/586 (14%)

Query: 1092 EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDD 1151
            E  I  + + +  LK+  +YV    A N+AG    S  +  V     P     V  VD  
Sbjct: 3695 EDKIATLEIPLAKLKDSGTYV--CTASNEAG---SSSCSATVTVREPPS---FVKKVDPS 3746

Query: 1152 GVI----SLNFECD-KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLG 1206
             ++    S    C  K +P  + +W K+     +S  + +    ++  +   D+ ++D G
Sbjct: 3747 YLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSG 3806

Query: 1207 IYSCDVTD---TDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFW 1263
             YSC+  +   +D  ++  +I E               P   +K+    +I+ +G     
Sbjct: 3807 SYSCEAVNDVGSDSCSTEIVIKE---------------PPSFIKTLEPADIV-RGTNALL 3850

Query: 1264 MQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDG 1323
                  +G  ++++  ++K+I    KY++   ++   +E+F     D  E       + G
Sbjct: 3851 QCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVG 3910

Query: 1324 KATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVT-GECNVLLKCKVAN 1382
            K    +T +L                     K+ P FV+ +   +  G   V L+  V  
Sbjct: 3911 KCGCMATHLL---------------------KEPPTFVKKVDDLIALGGQTVTLQAAVRG 3949

Query: 1383 IKKETHIVWYKDEREISVDE--KHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSR 1440
              +   + W K +  I  D   K  F +G+  L+I +      G Y  + +++ G   S 
Sbjct: 3950 -SEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTS- 4007

Query: 1441 LKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIR 1500
                     EL+++   KI   A    IQ TA       +      +LK  W  +G  + 
Sbjct: 4008 -------VGELIVKEPAKIIERAE--LIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLV 4058

Query: 1501 YSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR 1560
             S + +         L+      +D G+Y  E+   + G   + + +    D   A F  
Sbjct: 4059 ASKKYRISFKNNVAQLKFYSAELHDSGQYTFEI-SNEVG-SSSCETTFTVLDRDIAPF-- 4114

Query: 1561 LKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCN 1620
                             L +V ++  G    L C + G  P  VSW K+ K +A+ D   
Sbjct: 4115 -------------FTKPLRNVDSVVNG-TCRLDCKIAGSLPMRVSWFKDGKEIAASDRYR 4160

Query: 1621 LKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIP 1666
            + F  G TA   I  V   D+G +     N  GS+ S   + V  P
Sbjct: 4161 IAFVEG-TASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEP 4205



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 62/235 (26%), Positives = 100/235 (42%), Gaps = 13/235 (5%)

Query: 142   SGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQSTASKQ 201
             S RQ+ V+ IT+ EEE   E + + AQR   +S   +   ++S +       +  +   +
Sbjct: 32235 SRRQREVTEITEIEEEY--EISKH-AQRESSSSASRLLRRRRSLSPTYIELMRPVSELIR 32291

Query: 202   STAS-----KQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRK 256
             S        +  T  R  T  R    S    S+ +     E+ +R  +        +  K
Sbjct: 32292 SRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALK 32351

Query: 257   TLEETETYHAKLNEDH--LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQ 314
             T + +E  +  L++    L HAP   ++ RSH V   +N +   ++   P   V WY N 
Sbjct: 32352 TQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNG 32411

Query: 315   VPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
             V +       K    +  G+ TLEI  C  +D+  YRA   N KGE S YA++ V
Sbjct: 32412 VELQ---ESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463



 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 81/390 (20%), Positives = 142/390 (36%), Gaps = 58/390 (14%)

Query: 1282 KEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKL 1341
            KE+    KYK+        +++    +   D G Y+F++Q+    +  T  L        
Sbjct: 7624 KELTSDNKYKISFFNKVSGLKII--NVAPSDSGVYSFEVQNPVGKDSCTASL-------- 7673

Query: 1342 QKEAEFQRQEWIRKQGPHFVEYLSWEVTG--ECNVLLKCKVANIKKETHIVWYKDEREIS 1399
                    Q   R   P F   L  E  G    +V+++CKV        + W+ +  EIS
Sbjct: 7674 --------QVSDRTVPPSFTRKLK-ETNGLSGSSVVMECKVYG-SPPISVSWFHEGNEIS 7723

Query: 1400 VDEKHD--FKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCK 1457
               K+     D  C L +    + D+G Y  I  +  G D+    L        + +   
Sbjct: 7724 SGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDP 7783

Query: 1458 KIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQ 1517
               L+ T++   S  +G   +S          V+W    S +   DR    +      L+
Sbjct: 7784 MDVLTGTNVTFTSIVKGTPPFS----------VSWFKGSSELVPGDRCNVSLEDSVAELE 7833

Query: 1518 INEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEF-QRLKQAAIAEKNRARVLG 1576
            + +   +  G+Y   + +       T  L    Y +A A+F +RL               
Sbjct: 7834 LFDVDTSQSGEYTCIVSNEAGKASCTTHL----YIKAPAKFVKRLND------------- 7876

Query: 1577 GLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGV 1636
                  +I++GK L L     G PP  V+W KN   +     CN+     ++A   I   
Sbjct: 7877 -----YSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNIT-TTEKSAILEIPSS 7930

Query: 1637 STADSGKYGLVVKNKYGSETSDFTVSVFIP 1666
            +  D+G+Y   ++N  G ++    + +  P
Sbjct: 7931 TVEDAGQYNCYIENASGKDSCSAQILILEP 7960



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 79/374 (21%), Positives = 143/374 (38%), Gaps = 61/374 (16%)

Query: 1289 KYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD--GKATNHSTVVLVGDVFKKLQKEAE 1346
            KY++    N   ++ +  +L D   G YTF++ +  G ++  +T  ++            
Sbjct: 4062 KYRISFKNNVAQLKFYSAELHDS--GQYTFEISNEVGSSSCETTFTVLD----------- 4108

Query: 1347 FQRQEWIRKQGPHFVEYL---SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEK 1403
                   R   P F + L      V G C   L CK+A       + W+KD +EI+  ++
Sbjct: 4109 -------RDIAPFFTKPLRNVDSVVNGTCR--LDCKIAG-SLPMRVSWFKDGKEIAASDR 4158

Query: 1404 HD--FKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIAL 1461
            +   F +G  +L I      DAG +     +  G   S   L+ +     + +   K  L
Sbjct: 4159 YRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVL 4218

Query: 1462 SATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEP 1521
              + + ++ST +G             L + W      +         V+G   ++   E 
Sbjct: 4219 PGSAVCLKSTFQGST----------PLTIRWFKGNKEL---------VSGGSCYIT-KEA 4258

Query: 1522 TPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDV 1581
              +    Y+++  D  T   K  +++G    E  A     + A   EK     L      
Sbjct: 4259 LESSLELYLVKTSDSGTYTCKVSNVAGGV--ECSANLFVKEPATFVEKLEPSQL------ 4310

Query: 1582 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
              +++G A  L C V G PP +++W  N++ +       + F    TA   +  V   DS
Sbjct: 4311 --LKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSF-VESTAVLRLTDVGIEDS 4367

Query: 1642 GKYGLVVKNKYGSE 1655
            G+Y    +N+ GS+
Sbjct: 4368 GEYMCEAQNEAGSD 4381



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 114/567 (20%), Positives = 201/567 (35%), Gaps = 78/567 (13%)

Query: 1110 SYVFRVRAINQAGVGKPSDLAGPVVAETR--PGTKEVVVNVDDDGVISLNFECDKMTPKS 1167
            +Y F+V    Q  VGK S  A   V++    P     + N       S   EC K+   S
Sbjct: 5773 TYTFQV----QNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILEC-KVAGSS 5827

Query: 1168 EFS--WSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLID 1225
              S  W  +        + +     N   +    L   D+G Y+C   +  G        
Sbjct: 5828 PISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAG-------- 5879

Query: 1226 EEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA--KVNYIFNEKE 1283
             +E + +L +     F    VK    +E+L    V F      + G    KVN+    +E
Sbjct: 5880 SDECRAVLTVQEPPSF----VKEPEPLEVLPGKNVTF---TSVIRGTPPFKVNWFRGARE 5932

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQK 1343
            + +G +  ++ +     +E+F   +     G YT  + +       T  L       +++
Sbjct: 5933 LVKGDRCNIYFEDTVAELELF--NIDISQSGEYTCVVSNNAGQASCTTRLF------VKE 5984

Query: 1344 EAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEK 1403
             A F     +++   H VE       G+  +L       +     + W KD   I+  EK
Sbjct: 5985 PAAF-----LKRLSDHSVE------PGKSIILESTYTGTL--PISVTWKKDGFNITTSEK 6031

Query: 1404 HDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIAL 1461
             +    +  C L I   +K+DAG Y   ++++ G+D     +        + E+    A 
Sbjct: 6032 CNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAA 6091

Query: 1462 SATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEP 1521
                + +Q    G            ++ V+W    + +R +   +T  T     L  N+ 
Sbjct: 6092 VGDSVSLQCQVAG----------TPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKV 6141

Query: 1522 TPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDV 1581
              ND G+Y            K  +  G A  +     Q  +       + AR L  +   
Sbjct: 6142 NINDSGEYTC----------KAENSIGTASSKTVFRIQERQ----LPPSFARQLKDIEQT 6187

Query: 1582 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
            V    G  + LTC + G  P +V W ++   L  D++    F     A   I     + S
Sbjct: 6188 V----GLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSF-VDNVATLKILQTDLSHS 6242

Query: 1642 GKYGLVVKNKYGSETSDFTVSVFIPEE 1668
            G+Y     N  G+ +S   ++   P++
Sbjct: 6243 GQYSCSASNPLGTASSSARLTAREPKK 6269



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 105/531 (19%), Positives = 200/531 (37%), Gaps = 98/531 (18%)

Query: 1147 NVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLG 1206
            N++     + +FEC+         W K+ V  E S + ++  +G   ++   +   +D  
Sbjct: 2890 NIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSA 2949

Query: 1207 IYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQA 1266
             Y+  V   D ++++  +    +  +L   +  +  T+  +    V +  +G    W++ 
Sbjct: 2950 EYTF-VCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFE----VTVNYEGISYKWLK- 3003

Query: 1267 EKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKAT 1326
                         N  EI    K +M   + T  + +    +   D   YTF    GKAT
Sbjct: 3004 -------------NGVEIKSTDKCQMRTKKLTHSLNI--RNVHFGDAADYTFVA--GKAT 3046

Query: 1327 NHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKE 1386
            + +T+ +         +  EF++         H  +    +V  +   + +C+V+  + +
Sbjct: 3047 STATLYVEA-------RHIEFRK---------HIKDI---KVLEKKRAMFECEVS--EPD 3085

Query: 1387 THIVWYKDEREISVDEKHDFKDG--ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLV 1444
              + W KD++E+ + ++   +    +  LLI      DAG Y V+     G + S  KL 
Sbjct: 3086 ITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA----GGNVSTAKLF 3141

Query: 1445 DEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVE------DLKVNWSHNGSA 1498
             E                  D++I+S  + +Q+       VE      D+  +W  +G  
Sbjct: 3142 VEG----------------RDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIE 3185

Query: 1499 IRYS--DRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYA 1556
            I +   +R K  V      + I+E   +D G+Y      G+     T+ ++     +   
Sbjct: 3186 INFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA--GRNRSSVTLYVNAPEPPQVLQ 3243

Query: 1557 EFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD 1616
            E Q                      VT+Q GK       + G P P++SW K E+ L++ 
Sbjct: 3244 ELQP---------------------VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTG 3282

Query: 1617 DHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPE 1667
              C    +        I      D+  Y    KN YG  T+  ++SV +PE
Sbjct: 3283 FKCKFLHDGQEYTLLLIEAF-PEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 46/149 (30%), Positives = 67/149 (44%), Gaps = 9/149 (6%)

Query: 637   VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             VP PP  + V++ +R  V L+W  P   G   I  Y VEKC    E W RV      +  
Sbjct: 31121 VPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ---ARET 31177

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV-GDKLDIPKAPGKIIPSRNTDTS 754
             R+ + +L    SY FRV   N  G+ +PSE +E T+   DK        ++  +R     
Sbjct: 31178 RYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR----E 31233

Query: 755   VVVSWEESKDAKELVGYYIEASVAGSGKW 783
             V ++       KEL   Y+ A   G G++
Sbjct: 31234 VSMTKASHSSTKELYEKYMIAEDLGRGEF 31262



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 101/468 (21%), Positives = 186/468 (39%), Gaps = 77/468 (16%)

Query: 1073  YFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGP 1132
             +F D  E K K  ++  +++ A++ + +    L +   Y   VR    +G+         
Sbjct: 12406 WFKDGAEIK-KGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLT------- 12457

Query: 1133  VVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNK 1192
             V+ E    TK +  N++     ++   C+   P +E  W K      ++ R E+ ++G K
Sbjct: 12458 VLEEEAVFTKNLA-NIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRK 12516

Query: 1193  TKMTFKDLGMDDLGIYSCDVTD--TDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSEL 1250
               +  ++  ++D G Y+C +    TDG    + +  E + +   L               
Sbjct: 12517 RILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL--------------- 12561

Query: 1251  AVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQD 1310
               EILE  +  F     K S    V +  ++K +  G KY +  D    ++ +    LQD
Sbjct: 12562 --EILEGEKAEFVCSISKES--FPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQD 12617

Query: 1311  EDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTG 1370
                GTY   +   +A  H TV+    +   L+     ++QE                   
Sbjct: 12618 M--GTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQE------------------- 12656

Query: 1371  ECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIYEV 1428
                V+  C+V    +     W+++E  I    K+    KD + TL I +    D   Y V
Sbjct: 12657 ---VVFNCEVNT--EGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNV 12711

Query: 1429  ILKDDRGKD-KSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVED 1487
              L + RG++ KS   L+ E     ++E  K I             E ++  S VT++ + 
Sbjct: 12712 SLTNHRGENVKSAANLIVEEEDLRIVEPLKDI-------------ETMEKKS-VTFWCKV 12757

Query: 1488  LKVN----WSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
              ++N    W+ NG  + + +RV   V   +  L I +    D+G+Y++
Sbjct: 12758 NRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIV 12805



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 14/165 (8%)

Query: 1038  VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
             VP PP  +K S+V +DS+ L W  P   G + +T Y V+  +     ++W  + +A  + 
Sbjct: 31121 VPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVE--KCATTAERWLRVGQA--RE 31176

Query: 1098  VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN 1157
                 V  L    SY FRV A N+ G+ KPS+ + P + +     K   +N D++   +  
Sbjct: 31177 TRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE---DKTRAMNYDEEVDETRE 31233

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLE-------VESKGNKTKM 1195
                 K +  S     + Y+  ED  R E       VE+   KT M
Sbjct: 31234 VSMTKASHSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYM 31278



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 102/499 (20%), Positives = 176/499 (35%), Gaps = 65/499 (13%)

Query: 1171 WSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELK 1230
            W +D V   D   L+     N   +      +   G YSC  ++  G ASS         
Sbjct: 6208 WYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASS--------S 6259

Query: 1231 RLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKY 1290
              L      K P   +K  ++++++      F       +   ++ +  + KEI  G  Y
Sbjct: 6260 ARLTAREPKKSPFFDIK-PVSIDVIAGESADFECHVTG-AQPMRITWSKDNKEIRPGGNY 6317

Query: 1291 KMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQ 1350
             +    NT  + +   K+   D G YT Q  +    +  +  L      K  K+ E  + 
Sbjct: 6318 TITCVGNTPHLRIL--KVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASK- 6374

Query: 1351 EWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHD--FKD 1408
              + KQG               ++ L+CK++    E  + W++++ E+    K++  F +
Sbjct: 6375 --VAKQGE--------------SIQLECKISG-SPEIKVSWFRNDSELHESWKYNMSFIN 6417

Query: 1409 GICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKI 1468
             +  L I E S +D+G Y     +  G       L  +A      +     AL  +D+ +
Sbjct: 6418 SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVIL 6477

Query: 1469 QSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGK 1528
            Q    G   +  V          W  +   +R S + K         L I     +D G+
Sbjct: 6478 QCEISGTPPFEVV----------WVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGE 6527

Query: 1529 YVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGK 1588
            Y          H K  +  G        +F          K   R +  L D  T+  G 
Sbjct: 6528 Y----------HCKATNEVGSDTCSCSVKF----------KEPPRFVKKLSDTSTL-IGD 6566

Query: 1589 ALNLTCNVWGDPPPEVSWLKNE-KALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLV 1647
            A+ L   V G  P  V WLK+  + +   ++  + F     A   +     ++SGKY   
Sbjct: 6567 AVELRAIVEGFQPISVVWLKDRGEVIRESENTRISF-IDNIATLQLGSPEASNSGKYICQ 6625

Query: 1648 VKNKYGSETSDFTVSVFIP 1666
            +KN  G       ++V  P
Sbjct: 6626 IKNDAGMRECSAVLTVLEP 6644



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 36/116 (31%), Positives = 59/116 (50%), Gaps = 7/116 (6%)

Query: 1036  IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE--DQWRGLNEA 1093
             I +PGP   +K S++ K S  L W+PP   G TP+  Y ++ +EA  +       G N+ 
Sbjct: 14477 IGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKL 14536

Query: 1094  AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD 1149
             +       V+ L     Y FRV+A+N+ G G+  +L  PV+A+      +  V+V+
Sbjct: 14537 S-----WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 14587



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 96/288 (33%)

Query: 1489  KVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY--VMELFDGKTGHQKTVDL 1546
             +V W HNG  ++ S ++    T   + L+I +   +D G Y  V   + G+     T+D+
Sbjct: 32404 EVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463

Query: 1547  SGQAYD----------------------EAYA--EFQR---------------------- 1560
             +G  Y                       EAYA   F++                      
Sbjct: 32464 TGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRE 32523

Query: 1561  ------------LKQAAIAEKN--------------RARVLGGLPDVVTIQEGKALNLTC 1594
                         +K AA+ EK+               AR+L   P  +T+ EG++   +C
Sbjct: 32524 SLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTK-PRSMTVYEGESARFSC 32582

Query: 1595  NVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAY---FTINGVSTADSGKYGLVVKNK 1651
             +  G+P P V+WL+  + L++    + + +   T Y   F I+ V  +D G Y +VV+N 
Sbjct: 32583 DTDGEPVPTVTWLRKGQVLST----SARHQVTTTKYKSTFEISSVQASDEGNYSVVVENS 32638

Query: 1652  YGSETSDFTVSV--------------FIPEEEARMAALESLKGGKKAK 1685
              G + ++FT+++               +   E R+ + E++K  K+ K
Sbjct: 32639 EGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVK 32686



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 102/522 (19%), Positives = 181/522 (34%), Gaps = 66/522 (12%)

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG--IASS 1221
            TP    SW KD      S R  +      T +   +  ++D   YSC + +  G  I  +
Sbjct: 6953 TPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEA 7012

Query: 1222 YLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNE 1281
             +   E    +  L H       P   +  V+   + ++ ++ +  KL            
Sbjct: 7013 LVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLR----------- 7061

Query: 1282 KEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKL 1341
                  P YKM    N  +  + + K+   D G Y+ +  +      S+ VL   V K  
Sbjct: 7062 ----SAPAYKMQFKNN--VASLVINKVDHSDVGEYSCKADNSVGAVASSAVL---VIKAR 7112

Query: 1342 QKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVD 1401
            +    F R    + +  H  E L + V  EC +       N  +   + WYKD   +  D
Sbjct: 7113 KLPPFFAR----KLKDVH--ETLGFPVAFECRI-------NGSEPLQVSWYKDGVLLKDD 7159

Query: 1402 E--KHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKI 1459
               +  F   + TL I +  +   G Y     +  G   S  KL+    +       K +
Sbjct: 7160 ANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPV 7219

Query: 1460 ALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN 1519
            ++   DL +  +      +         +K+ W+ +   IR     K  +      L + 
Sbjct: 7220 SV---DLALGESG----TFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVL 7272

Query: 1520 EPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLP 1579
            +    D G+Y             T   S  A  ++ +       A +  +   R +  L 
Sbjct: 7273 KVGKGDAGQY-------------TCYASNIAGKDSCS-------AQLGVQEPPRFIKKLE 7312

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
                +++ +     C + G P  +V W K+E  +       + F     A   ++ +S  
Sbjct: 7313 PSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF-VDSVAVLEMHNLSVE 7371

Query: 1640 DSGKYGLVVKNKYGSETSDFTVSVFIPE-EEARMAALESLKG 1680
            DSG Y     N  GS +S  ++ V  P     +   +E+LKG
Sbjct: 7372 DSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKG 7413



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 103/508 (20%), Positives = 188/508 (37%), Gaps = 43/508 (8%)

Query: 1165 PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLI 1224
            P+ + SW K+        + +    G +  +   +   +D  +Y+C+  +  G+A++   
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3325

Query: 1225 DEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQ-VRFWMQAEKLSGNAKVNYIFNEKE 1283
               E+  +++   E       + + L   +  +GQ  RF  Q      + KV++   +K+
Sbjct: 3326 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARF--QCRVSGTDLKVSWYSKDKK 3383

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQK 1343
            I     ++M    +T  +E+   +   EDEGTYTF   +      ST  L  +  + +  
Sbjct: 3384 IKPSRFFRMTQFEDTYQLEI--AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILH 3441

Query: 1344 EAEFQRQEWIRKQGPHFVEYLS-WEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDE 1402
            E   Q  E   K  P     +   EV         C++ +        W+K  REI   +
Sbjct: 3442 ERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQS-APNVRFQWFKAGREIYESD 3500

Query: 1403 KHDFKDG--ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL-VDEAFKELMMEVCKKI 1459
            K   +    I +L I      D G Y     ++ G       L V EA+    +   K +
Sbjct: 3501 KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSL 3560

Query: 1460 -ALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQI 1518
                    K   T  G  +          ++  W  +G+A+  S   +      +  L++
Sbjct: 3561 TTFVGKAAKFICTVTGTPV----------IETIWQKDGAALSPSPNWRISDAENKHILEL 3610

Query: 1519 NEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGL 1578
            +  T  D+G Y                 S +A ++  A+  + +   I + +  + L  +
Sbjct: 3611 SNLTIQDRGVY-----------------SCKASNKFGADICQAELIIIDKPHFIKELEPV 3653

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
               +     K ++L C V  D    V+W K+ + L       + FE  + A   I     
Sbjct: 3654 QSAI----NKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFE-DKIATLEIPLAKL 3708

Query: 1639 ADSGKYGLVVKNKYGSETSDFTVSVFIP 1666
             DSG Y     N+ GS +   TV+V  P
Sbjct: 3709 KDSGTYVCTASNEAGSSSCSATVTVREP 3736



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 93/508 (18%), Positives = 193/508 (37%), Gaps = 82/508 (16%)

Query: 1170 SWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEEL 1229
            +W KD     +   + +  + N   +    + +   G Y C   +  GI        +  
Sbjct: 4518 TWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGI--------QRC 4569

Query: 1230 KRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVN--YIFNEKEIFEG 1287
              LL++    K P    +  +++++ +       +   K SG  ++   +  + +E+  G
Sbjct: 4570 SALLSV----KEPATITEEAVSIDVTQGDPATLQV---KFSGTKEITAKWFKDGQELTLG 4622

Query: 1288 PKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDG------KATNHSTVVLVGDVFKKL 1341
             KYK+ +     I+++     + +D G YTF++Q+       KA  +   +++   F K 
Sbjct: 4623 SKYKISVTDTVSILKII--STEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKK 4680

Query: 1342 QKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVD 1401
             K+ +  +  +I                      L+C VA       I W+KD++EIS  
Sbjct: 4681 LKKMDSIKGSFID---------------------LECIVAG-SHPISIQWFKDDQEISAS 4718

Query: 1402 EKHDFK--DGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKI 1459
            EK+ F   D    L I++    D+G Y     +  G ++    L  +     + +   + 
Sbjct: 4719 EKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQD 4778

Query: 1460 ALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIR-YSDRVKTGVTGEQIWLQI 1518
                T +++++   G    + + ++ ++ ++   H+G+A   + D   T        L++
Sbjct: 4779 VNPNTRVQLKALVGGTAPMT-IKWFKDNKEL---HSGAARSVWKDDTSTS-------LEL 4827

Query: 1519 NEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGL 1578
                  D G Y+ +L +            G A            +A +  K   + +   
Sbjct: 4828 FAAKATDSGTYICQLSNDV----------GTA----------TSKATLFVKEPPQFIKKP 4867

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
              V+ ++ G++    C + G P   VSW  +   + +     + F  G  A F I+G   
Sbjct: 4868 SPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDG-LATFQISGARV 4926

Query: 1639 ADSGKYGLVVKNKYGSETSDFTVSVFIP 1666
             +SG Y    +N  G+ +    + V  P
Sbjct: 4927 ENSGTYVCEARNDAGTASCSIELKVKEP 4954



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 57/235 (24%), Positives = 100/235 (42%), Gaps = 27/235 (11%)

Query: 1466  LKIQSTAEGIQLYSFVTYYVEDLK-VNWSHNGSAIRYSDRVKTGVTGEQIW-LQINEPTP 1523
             LK +++ E  +L   V   V   K V W  +G  ++ +   +   + +  + L+IN  T 
Sbjct: 32724 LKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 32783

Query: 1524  NDKGKYVMELFDGKTGHQKT-VDLSGQAY----------DEAYAEFQRLKQAAIAEKNRA 1572
             +D+G+YV E+  G+ G  KT +   GQA+           E     Q+  ++ +  K   
Sbjct: 32784 SDQGEYVCEI-SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP 32842

Query: 1573  R----------VLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLK 1622
             +          ++ GL D  T+             G+P P   W K+ KA+       L 
Sbjct: 32843 KAPEPISSKPVIVTGLQD-TTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS 32901

Query: 1623  FEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV-FIPEEEARMAALE 1676
              + G   +  I+   T+DSG Y   VKN  GS +S   +++  I + EA+  + +
Sbjct: 32902 EDKG-GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 32955



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 96/519 (18%), Positives = 188/519 (36%), Gaps = 75/519 (14%)

Query: 1155 SLNFECDKMTPKSEFS--WSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
            S++ EC K++     S  W KD      S +  +        +   +L ++D   Y+C V
Sbjct: 5253 SIHMEC-KVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKV 5311

Query: 1213 TDT--DGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLS 1270
            ++   D   S  L  +E    L+    +   P     S +  + + KG   F        
Sbjct: 5312 SNVAGDDACSGILTVKEPPSFLVKPGRQQAIP----DSTVEFKAILKGTPPF-------- 5359

Query: 1271 GNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHST 1330
               K+ +  ++ E+  GPK  + ++ +T  + ++   +     G YT  + +   ++  T
Sbjct: 5360 ---KIKWFKDDVELVSGPKCFIGLEGSTSFLNLY--SVDASKTGQYTCHVTNDVGSDSCT 5414

Query: 1331 VVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIV 1390
             +L+     K  K+ E  +   I K G               +  L+CK+A    E  +V
Sbjct: 5415 TMLLVTEPPKFVKKLEASK---IVKAGD--------------SSRLECKIAG-SPEIRVV 5456

Query: 1391 WYKDEREISVDEKH--DFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAF 1448
            W+++E E+   +K+   F D +  + +   S +D+G +    ++  G      K++ +  
Sbjct: 5457 WFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP 5516

Query: 1449 KELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTG 1508
                        L   ++ ++    G   +  V          W  +   +R S + K  
Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVV----------WYKDKRQLRSSKKYKIA 5566

Query: 1509 VTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAE 1568
                   + I     +D G+Y  +    + G    V                     +  
Sbjct: 5567 SKNFHTSIHILNVDTSDIGEYHCKA-QNEVGSDTCV-------------------CTVKL 5606

Query: 1569 KNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLK-NEKALASDDHCNLKFEAGR 1627
            K   R +  L + +T+  G+   L  ++ G  P  V WLK  E+ +   ++  + F    
Sbjct: 5607 KEPPRFVSKL-NSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITF-VEN 5664

Query: 1628 TAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIP 1666
             A         A++GKY   +KN  G   +  T+ V  P
Sbjct: 5665 VATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEP 5703



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 52/212 (24%), Positives = 80/212 (37%), Gaps = 43/212 (20%)

Query: 273  LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY 332
            +L  P F+ +     V   ++  L C +AG PE  V+WYK    +        Y +  R 
Sbjct: 7957 ILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTT---YKMHFRN 8013

Query: 333  GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF 392
             + TL  N  D  D+ +Y   A N  GE+SA   + V+                      
Sbjct: 8014 NVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQ---------------------- 8051

Query: 393  GVTPYGYASRFEIHFDDKFDVSFGREGETM--SLGCRVVITPEIKHFQP-EIQWYRNGVP 449
                           + K   SF R+   +  ++G  VV    I   +P  + WY++G P
Sbjct: 8052 ---------------EQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKP 8096

Query: 450  LSPSKWVQTLWSGERATLTFSHLNKEDEGLYT 481
            L  S  VQT +    ATL     ++   G Y+
Sbjct: 8097 LKDSPNVQTSFLDNTATLNIFKTDRSLAGQYS 8128



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 75/381 (19%), Positives = 137/381 (35%), Gaps = 56/381 (14%)

Query: 1291 KMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTV-VLVGDVFKKLQKEAEFQR 1349
            K HI     +  + +   +  D+G Y+F++++    ++ TV V V D             
Sbjct: 6690 KHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSD------------- 6736

Query: 1350 QEWIRKQGPHFVEYLSWEVTG--ECNVLLKCKVANIKKETHIVWYKDEREISVDEK--HD 1405
                R   P F+  L  +V      +V+L+C+V+       + W++D  EI    K    
Sbjct: 6737 ----RIVPPSFIRKLK-DVNAILGASVVLECRVSG-SAPISVGWFQDGNEIVSGPKCQSS 6790

Query: 1406 FKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATD 1465
            F + +CTL ++     D GIY  +  +  G D+    L  +              L    
Sbjct: 6791 FSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMS 6850

Query: 1466 LKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPND 1525
            L   S   G   +          KV W      +   +     +      L++ E  P +
Sbjct: 6851 LTFTSVIRGTPPF----------KVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLE 6900

Query: 1526 KGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQ 1585
             G Y   + +       T  L              +K+ A   K  A          +++
Sbjct: 6901 SGDYSCLVTNDAGSASCTTHLF-------------VKEPATFVKRLADF--------SVE 6939

Query: 1586 EGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYG 1645
             G  + L     G PP  VSW+K+E  ++  + C++     ++    I   +  D  +Y 
Sbjct: 6940 TGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITM-TEKSTILEILESTIEDYAQYS 6998

Query: 1646 LVVKNKYGSETSDFTVSVFIP 1666
             +++N+ G +  +  VSV  P
Sbjct: 6999 CLIENEAGQDICEALVSVLEP 7019



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 148/740 (20%), Positives = 274/740 (37%), Gaps = 142/740 (19%)

Query: 983  WREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPP 1042
            W + N++       +I+     +V Q + A MN AGL              +T  V    
Sbjct: 8283 WYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGL--------------YTCKVSNDA 8328

Query: 1043 HSLKCSEVRKDSLVLQW--KPPVHSGR-TPVT---GYFVDLK-EAKAKED---QW----- 1087
             S  C+     S+V++   KPPV     TPVT   G +V L    +  E    QW     
Sbjct: 8329 GSALCTS----SIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGR 8384

Query: 1088 ------RGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGV----GKPSDLAGPVVAET 1137
                  R     A     L++R + +  S  +  +A N AG      K +    P VA  
Sbjct: 8385 EIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVA-- 8442

Query: 1138 RPGTKEVVVNVDDDGVISLNFE------CDKMT----------PKSEFSWSKD-YVSTED 1180
             P TK+  V    DG +    E       +K T          P     W+K  +     
Sbjct: 8443 -PATKKAAV----DGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQ 8497

Query: 1181 SPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL---IDEEELKRLLALSH 1237
              R+ +  KG++ K+  +D    D G+Y C   +  G   S +   +DE + +  +    
Sbjct: 8498 GGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDL 8557

Query: 1238 EHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKY-KMH-ID 1295
                   P        IL+KG      + E++     +  +    +  E  KY +M+ I 
Sbjct: 8558 RAMLKKTP--------ILKKGAG----EEEEID----IMELLKNVDPKEYEKYARMYGIT 8601

Query: 1296 RNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRK 1355
               G+++ F    Q ++E T+  ++++ + +            K+ ++   F +Q   + 
Sbjct: 8602 DFRGLLQAFELLKQSQEEETHRLEIEEIERSERDE--------KEFEELVSFIQQRLSQT 8653

Query: 1356 QGPHFVEYLSWE-VTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFK-DGIC-T 1412
            +    ++ +  + V  + + + +  +     E  + WYK   ++   +K +   DG   T
Sbjct: 8654 EPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHT 8713

Query: 1413 LLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTA 1472
            L +     KD G Y ++        K  L +++ A++  + +V  K              
Sbjct: 8714 LRVKNCQLKDQGNYRLVCGPHIASAK--LTVIEPAWERHLQDVTLK-------------- 8757

Query: 1473 EGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVME 1532
            EG        + V ++K  W  NG  ++   R KT V  +   L I +    D+G+Y  +
Sbjct: 8758 EGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCK 8817

Query: 1533 LFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNL 1592
              D +T  +  ++       E     +R++                   + + E ++   
Sbjct: 8818 YEDLETSAELRIEA------EPIQFTKRIQN------------------IVVSEHQSATF 8853

Query: 1593 TCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKY 1652
             C V  D    V+W K    L      N + + GR  Y TI+ V+  D G Y ++ + + 
Sbjct: 8854 ECEVSFD-DAIVTWYKGPTELTESQKYNFRND-GRCHYMTIHNVTPDDEGVYSVIARLEP 8911

Query: 1653 GSETSDFTVSVFIPEEEARM 1672
              E    T  +++  +E ++
Sbjct: 8912 RGEARS-TAELYLTTKEIKL 8930



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 98/507 (19%), Positives = 176/507 (34%), Gaps = 83/507 (16%)

Query: 1170 SWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEEL 1229
            SW KD      S R  +        +    + M+D G ++C  T++ G   S        
Sbjct: 4145 SWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDS-------- 4196

Query: 1230 KRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPK 1289
               L +     F T P   ++       G         + S    + +    KE+  G  
Sbjct: 4197 SGALIVQEPPSFVTKPGSKDVL-----PGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGS 4251

Query: 1290 YKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQR 1349
              +  +     +E+++ K  D   GTYT ++ +          + G V        E   
Sbjct: 4252 CYITKEALESSLELYLVKTSDS--GTYTCKVSN----------VAGGV--------ECSA 4291

Query: 1350 QEWIRKQGPHFVEYLSWEVTGECNVLLK--------CKVANIKKETHIVWYKDEREISVD 1401
              ++ K+   FVE L      E + LLK        CKV        I W+ ++REI   
Sbjct: 4292 NLFV-KEPATFVEKL------EPSQLLKKGDATQLACKVTGTPP-IKITWFANDREIKES 4343

Query: 1402 EKH--DFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKI 1459
             KH   F +    L +T+   +D+G Y    +++ G D     ++ +       E     
Sbjct: 4344 SKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIE 4403

Query: 1460 ALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN 1519
             L   D+ + +   G   +          ++ W  + + +R   + KT +    + LQI 
Sbjct: 4404 VLKEYDVMLLAEVAGTPPF----------EITWFKDNTILRSGRKYKTFIQDHLVSLQIL 4453

Query: 1520 EPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLP 1579
            +    D G+Y   +   + G                     +  A +  +     +  + 
Sbjct: 4454 KFVAADAGEYQCRV-TNEVG-------------------SSICSARVTLREPPSFIKKIE 4493

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
               +++ G A      + G  P  V+WLK+   +  DD+  + FE    A   ++G+   
Sbjct: 4494 STSSLRGGTAA-FQATLKGSLPITVTWLKDSDEITEDDNIRMTFE-NNVASLYLSGIEVK 4551

Query: 1640 DSGKYGLVVKNKYGSETSDFTVSVFIP 1666
              GKY    KN  G +     +SV  P
Sbjct: 4552 HDGKYVCQAKNDAGIQRCSALLSVKEP 4578



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 53/229 (23%), Positives = 89/229 (38%), Gaps = 40/229 (17%)

Query: 273  LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY 332
            L   P FI K  + T   K +     ++AG P   +TW K+   ++   N     ++S  
Sbjct: 5044 LKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDS-- 5101

Query: 333  GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF 392
             + TL+I   D   + +Y   A N  G    YA ++V+      ++ +          S 
Sbjct: 5102 -VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAK----------SV 5150

Query: 393  GVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSP 452
             VT                      E + M+L C V  TPE+K     ++W ++G  + P
Sbjct: 5151 DVT----------------------EKDPMTLECVVAGTPELK-----VKWLKDGKQIVP 5183

Query: 453  SKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRD 501
            S++    +    A+     + K+D G YT +V          AY+ V D
Sbjct: 5184 SRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLD 5232



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 93/428 (21%), Positives = 159/428 (37%), Gaps = 58/428 (13%)

Query: 1039  PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1098
             PGP   L  S V ++   L W  P   G   +T Y V+ +E       W  +        
Sbjct: 29141 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLN--WVIVEGECPTLS 29198

Query: 1099  YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA--------------ETRPGTKEV 1144
             Y+  R +K    Y+FRVRA+N+ G G P + + P+VA              E   G + +
Sbjct: 29199 YVVTRLIKNN-EYIFRVRAVNKYGPGVPVE-SEPIVARNSFTIPSPPGIPEEVGTGKEHI 29256

Query: 1145  VVN----VDDDGVISLNFECDKMTPKSEFSWS---KDYVSTEDSPRLEVESKGNKTKMTF 1197
             ++       D G    N+  DK   KS   W+   KDYV  +            + K+T 
Sbjct: 29257 IIQWTKPESDGGNEISNYLVDKREKKS-LRWTRVNKDYVVYD-----------TRLKVTS 29304

Query: 1198  KDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEK 1257
                G D    Y   VT  +   +S   +  E    ++   E  +   P  +   V+  + 
Sbjct: 29305 LMEGCD----YQFRVTAVNAAGNS---EPSEASNFISC-REPSYTPGPPSAPRVVDTTKH 29356

Query: 1258  GQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
                  W +     G   V Y+   +E      Y++H +      E  +  L+   +  Y+
Sbjct: 29357 SISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK--YS 29414

Query: 1318  FQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLK 1377
             F++           V V  + +  +  AE +  E I        + L   VT      L+
Sbjct: 29415 FRV---------AAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLR 29465

Query: 1378  CKVANIKKETHIV-WYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGK 1436
               V+   +   ++ W K   +++     D  +    L++ + ++ DAG Y +  ++  GK
Sbjct: 29466 LMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGK 29525

Query: 1437  DKSRLKLV 1444
              KS   LV
Sbjct: 29526 -KSATVLV 29532



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 92/500 (18%), Positives = 192/500 (38%), Gaps = 81/500 (16%)

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            TP  + +W  +    ++S +  +    +   +   D+G++D G Y C+  +  G      
Sbjct: 4326 TPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG------ 4379

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA--KVNYIFNE 1281
               +    ++ +     F     K    +E+L++  V   M   +++G    ++ +  + 
Sbjct: 4380 --SDHCSSIVIVKESPYF----TKEFKPIEVLKEYDV---MLLAEVAGTPPFEITWFKDN 4430

Query: 1282 KEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD--GKATNHSTVVLVGDVFK 1339
              +  G KYK  I  +  ++ + + K    D G Y  ++ +  G +   + V L      
Sbjct: 4431 TILRSGRKYKTFIQDH--LVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTL------ 4482

Query: 1340 KLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIV--WYKDERE 1397
                           ++ P F++ +  E T           A +K    I   W KD  E
Sbjct: 4483 ---------------REPPSFIKKI--ESTSSLRGGTAAFQATLKGSLPITVTWLKDSDE 4525

Query: 1398 ISVDE--KHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEV 1455
            I+ D+  +  F++ + +L ++    K  G Y    K+D G  +    L   + KE     
Sbjct: 4526 ITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALL---SVKEPATIT 4582

Query: 1456 CKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIW 1515
             + +++  T    Q     +Q+    T   +++   W  +G  +    + K  VT     
Sbjct: 4583 EEAVSIDVT----QGDPATLQVKFSGT---KEITAKWFKDGQELTLGSKYKISVTDTVSI 4635

Query: 1516 LQINEPTPNDKGKYVMELFD--GKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRAR 1573
            L+I      D G+Y  E+ +  G++  +  +++       ++ +  +LK+          
Sbjct: 4636 LKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTK--KLKKM--------- 4684

Query: 1574 VLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTI 1633
                  D +   +G  ++L C V G  P  + W K+++ +++ +     F    TA+  I
Sbjct: 4685 ------DSI---KGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFH-DNTAFLEI 4734

Query: 1634 NGVSTADSGKYGLVVKNKYG 1653
            + +   DSG Y     NK G
Sbjct: 4735 SQLEGTDSGTYTCSATNKAG 4754



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 100/495 (20%), Positives = 186/495 (37%), Gaps = 92/495 (18%)

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             FEC+     ++  W KD    +   + ++ SKG    +      +DD   YSC+V     
Sbjct: 12393 FECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTART 12452

Query: 1218  IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
                  +++EE                V  K+   +E+ E   ++   +  K    A+V +
Sbjct: 12453 SGMLTVLEEE---------------AVFTKNLANIEVSETDTIKLVCEVSK--PGAEVIW 12495

Query: 1278  IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQL----QDGKATNHSTVVL 1333
                ++EI E  +Y++  +    I  + ++    ED G Y  +L     DGK   H     
Sbjct: 12496 YKGDEEIIETGRYEILTEGRKRI--LVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAA- 12552

Query: 1334  VGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYK 1393
                              E+I K  P  +E L  E          C ++  K+   + W +
Sbjct: 12553 -----------------EFISK--PQNLEILEGE-----KAEFVCSIS--KESFPVQWKR 12586

Query: 1394  DEREISVDEKHD-FKDG-ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKEL 1451
             D++ +   +K+D   DG    L++ + + +D G Y V++   R    + L ++++     
Sbjct: 12587 DDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARA--AAHLTVIEKL---- 12640

Query: 1452  MMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTG 1511
                   +I +   D +++   E +      T   E  K  W  N  AI  S +       
Sbjct: 12641 ------RIVVPLKDTRVKEQQEVVFNCEVNT---EGAKAKWFRNEEAIFDSSKYIILQKD 12691

Query: 1512  EQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAA--IAEK 1569
                 L+I +   +D+  Y + L    T H+                 + +K AA  I E+
Sbjct: 12692 LVYTLRIRDAHLDDQANYNVSL----TNHRG----------------ENVKSAANLIVEE 12731

Query: 1570  NRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTA 1629
                R++  L D+ T+ E K++   C V       + W KN + +  D+  + + +  +  
Sbjct: 12732 EDLRIVEPLKDIETM-EKKSVTFWCKV-NRLNVTLKWTKNGEEVPFDNRVSYRVDKYK-H 12788

Query: 1630  YFTINGVSTADSGKY 1644
               TI      D G+Y
Sbjct: 12789 MLTIKDCGFPDEGEY 12803



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             +P+ +TI+ GK L +  +V+G P P   W K E  + +  H  +  +A  ++   I  V+
Sbjct: 18904 MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV-HKADSSSILIIKDVT 18962

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG Y L  +N  G++T    V V
Sbjct: 18963 RKDSGYYSLTAENSSGTDTQKIKVVV 18988



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 44/192 (22%), Positives = 83/192 (43%), Gaps = 30/192 (15%)

Query: 180   TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
             T   + +S + T+  ++++S +   S Q T +R+S +S +   S +  SA  +E++ E  
Sbjct: 32491 TEAYAVSSFKKTSEMEASSSVREVKS-QMTETRESLSSYEHSASAEMKSAALEEKSLE-- 32547

Query: 240   SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
                    EK+    ++ TL                 A   + KPRS TV+E E+ +  C 
Sbjct: 32548 -------EKSTTRKIKTTL-----------------AARILTKPRSMTVYEGESARFSCD 32583

Query: 300   IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
               G P P VTW +    ++  A   ++ + +     T EI+     D   Y     N +G
Sbjct: 32584 TDGEPVPTVTWLRKGQVLSTSA---RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEG 32640

Query: 360   ELSAYASVVVKR 371
             +  A  ++ +++
Sbjct: 32641 KQEAEFTLTIQK 32652



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 32/84 (38%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D +TI+ G+A  LT    G P P+VSW K+E  +  DD  ++K      A   I     +
Sbjct: 16826 DKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK-AKRS 16884

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             DSGKY +VV+N  GS      V+V
Sbjct: 16885 DSGKYCVVVENSTGSRKGFCQVNV 16908



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 47/166 (28%), Positives = 72/166 (43%), Gaps = 9/166 (5%)

Query: 1503  DRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQ--- 1559
             +R      G+  WL+ N    +D    V  L +G T   + +  +        +E     
Sbjct: 28976 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 29035

Query: 1560  --RLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDD 1617
               R + A    +  AR+ G   D+VTI+ G  L L   V G P P++ W K +K L   +
Sbjct: 29036 TCRDEYAPPKAELDARLHG---DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCE 29092

Query: 1618  HCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               +L++  G+ A   I     +DSGKY L VKN  G++     V V
Sbjct: 29093 KVSLQY-TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV 29137



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 47/205 (22%), Positives = 81/205 (39%), Gaps = 38/205 (18%)

Query: 277  PEFIIKPRSHT-VWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
            P + I+P  H      E   L C + G PE R++WYK    +    +   Y ++ +  + 
Sbjct: 7019 PPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLR---SAPAYKMQFKNNVA 7075

Query: 336  TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVT 395
            +L IN  D  D  +Y   A N  G +++ A +V+K  K                    + 
Sbjct: 7076 SLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK--------------------LP 7115

Query: 396  PYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKW 455
            P+      ++H    F V+F          CR+  +  +     ++ WY++GV L     
Sbjct: 7116 PFFARKLKDVHETLGFPVAF---------ECRINGSEPL-----QVSWYKDGVLLKDDAN 7161

Query: 456  VQTLWSGERATLTFSHLNKEDEGLY 480
            +QT +    ATL     ++   G Y
Sbjct: 7162 LQTSFVHNVATLQILQTDQSHIGQY 7186



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 101/517 (19%), Positives = 179/517 (34%), Gaps = 70/517 (13%)

Query: 1155 SLNFECDKM-TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVT 1213
            S  FEC    TPK   SW  D        +  +               +++ G Y C+  
Sbjct: 4878 STTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEAR 4937

Query: 1214 DTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
            +  G AS  +  E ++K       E K   V   S++ +E    G   F           
Sbjct: 4938 NDAGTASCSI--ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPF----------- 4984

Query: 1274 KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQ-DGKATNHSTVV 1332
            +V ++ N +EI    KY +  DR   +  + + K    D G Y   +  +G + + ST V
Sbjct: 4985 EVTWLKNNREIRSSKKYTL-TDR-VSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRV 5042

Query: 1333 LVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTG-ECNVLLKCKVANIKKETHIVW 1391
             +                    K+ P F++ +    T  + +   +  VA       I W
Sbjct: 5043 AL--------------------KEPPSFIKKIENTTTVLKSSATFQSTVAG-SPPISITW 5081

Query: 1392 YKDEREISVDEKH--DFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFK 1449
             KD++ +  D+     F D + TL I       +G Y    K++ G        V+  + 
Sbjct: 5082 LKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESG--------VERCYA 5133

Query: 1450 ELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGV 1509
             L+++   +I   A  + +  T +       V     +LKV W  +G  I  S       
Sbjct: 5134 FLLVQEPAQIVEKAKSVDV--TEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSF 5191

Query: 1510 TGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEK 1569
                   +I      D G+Y  ++ +         D    + D       +    +  +K
Sbjct: 5192 ENNVASFRIQSVMKQDSGQYTFKVEN---------DFGSSSCDAYLRVLDQNIPPSFTKK 5242

Query: 1570 NRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTA 1629
                 L  +  V+    G ++++ C V G  P    W K+ K +++     L     R+ 
Sbjct: 5243 -----LTKMDKVL----GSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHE-RSV 5292

Query: 1630 YFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIP 1666
               +N +   D+  Y   V N  G +     ++V  P
Sbjct: 5293 SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEP 5329



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 124/579 (21%), Positives = 217/579 (37%), Gaps = 83/579 (14%)

Query: 1099 YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNF 1158
            +L++  + +G S  +  +A N   VGK    A   V E     K++  +       S+  
Sbjct: 6327 HLRILKVGKGDSGQYTCQATND--VGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQL 6384

Query: 1159 ECD-KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            EC    +P+ + SW ++     +S +  +    +   +T  +   +D G Y C+  +  G
Sbjct: 6385 ECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVG 6444

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA--KV 1275
             AS             + +   K P V  +    V  L+   V   +Q E +SG    +V
Sbjct: 6445 DASC------------STALTVKAPPVFTQKPSPVGALKGSDVI--LQCE-ISGTPPFEV 6489

Query: 1276 NYIFNEKEIFEGPKYKM---HIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVV 1332
             ++ + K++    K+K+   H D +  I+      L+  D G Y       KATN     
Sbjct: 6490 VWVKDRKQVRNSKKFKITSKHFDTSLHILN-----LEASDVGEYHC-----KATNE---- 6535

Query: 1333 LVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWY 1392
             VG          +F       K+ P FV+ LS   T   + +    +    +   +VW 
Sbjct: 6536 -VGS--DTCSCSVKF-------KEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWL 6585

Query: 1393 KDEREI---SVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFK 1449
            KD  E+   S + +  F D I TL +      ++G Y   +K+D G  +    L      
Sbjct: 6586 KDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLT----- 6640

Query: 1450 ELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGV 1509
              ++E  + I     +    +T     L   VT   E L   W  +G  +    +     
Sbjct: 6641 --VLEPARII--EKPEPMTVTTGNPFALECVVTGTPE-LSAKWFKDGRELSADSKHHITF 6695

Query: 1510 TGEQIWLQINEPTPNDKGKYVMELFD--GKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIA 1567
              +   L+I     +DKG Y  E+ +  GK+    +V +S +    ++            
Sbjct: 6696 INKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSF------------ 6743

Query: 1568 EKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGR 1627
                   +  L DV  I  G ++ L C V G  P  V W ++   + S   C   F +  
Sbjct: 6744 -------IRKLKDVNAIL-GASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSF-SEN 6794

Query: 1628 TAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIP 1666
                 ++ +  +D+G Y  V  N  GS+     ++V  P
Sbjct: 6795 VCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEP 6833



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 78/375 (20%), Positives = 132/375 (35%), Gaps = 84/375 (22%)

Query: 184  STASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKV 243
            +T +K+    K++         ++S   R     R      +A +A++ +   + +S + 
Sbjct: 1970 TTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEE 2029

Query: 244  VIREKAERLSLRKTLEETETYHAKLNEDHLL----------------HAPEFIIKPRSHT 287
            ++R+  + L L  T E TE     L E+  +                 AP+   + +S T
Sbjct: 2030 LLRKTKDEL-LHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQT 2088

Query: 288  VWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDT 347
            V +  +      + G P+P   WYKN V I        Y  E    +  L I     ED+
Sbjct: 2089 VGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPED--NVCELVIRDVTAEDS 2146

Query: 348  AQYRASAMNVKGELSAYASVVVKRYK-------------GEFDETRFHAGASTMPLSFGV 394
            A     A+N+ GE S++A ++V+  +              E D        ++ P    V
Sbjct: 2147 ASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPF---V 2203

Query: 395  TPYGYASRFEIHFDDKFDVSFGR-----------------------EGETMSLGCRVVIT 431
                Y    E+H  DK+ +   R                       E E +    ++++ 
Sbjct: 2204 KVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVE 2263

Query: 432  PEIKHFQPEIQ------------------------WYRNGVPL-SPSKWVQTLWSGERAT 466
              +  F  E+Q                        WY N V L S  K+  T   G R  
Sbjct: 2264 GAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRG-RQN 2322

Query: 467  LTFSHLNKEDEGLYT 481
            LT   + KED+G Y+
Sbjct: 2323 LTVKDVTKEDQGEYS 2337



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 55/227 (24%), Positives = 79/227 (34%), Gaps = 39/227 (17%)

Query: 261  TETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVH 320
            T +  A+L       +P F IKP S  V   E+    C + G    R+TW K+   I   
Sbjct: 6255 TASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPG 6314

Query: 321  ANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETR 380
             N   Y I        L I      D+ QY   A N  G+    A + VK          
Sbjct: 6315 GN---YTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE--------- 6362

Query: 381  FHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPE 440
                           P  +  + E            ++GE++ L C++  +PEIK     
Sbjct: 6363 ---------------PPKFVKKLEAS-------KVAKQGESIQLECKISGSPEIK----- 6395

Query: 441  IQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMG 487
            + W+RN   L  S      +    A LT +  + ED G Y      G
Sbjct: 6396 VSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNG 6442



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 59/299 (19%), Positives = 114/299 (38%), Gaps = 36/299 (12%)

Query: 1373  NVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDG--ICTLLITEFSKKDAGIYEVIL 1430
             NVL  C+++  +    I W+K+   IS+           + +L I   S  D+G Y +  
Sbjct: 33150 NVLFTCEISG-EPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKA 33208

Query: 1431  KDDRGKDKSR-----LKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYV 1485
             K+ RG+  +      L LV+E  +E+++          T L+   +++ +Q+ +      
Sbjct: 33209 KNFRGQCSATASLMVLPLVEEPSREVVLRTS-----GDTSLQGSFSSQSVQMSAS----- 33258

Query: 1486  EDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVD 1545
                        S   +S    + +T  +      +   + +  +V        G      
Sbjct: 33259 -------KQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQ 33311

Query: 1546  LSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVS 1605
             L             ++ +A I  +     +  LP  ++I EGK L + C   G+P PEV+
Sbjct: 33312 LESST--------SKMLKAGI--RGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVT 33361

Query: 1606  WLKNEKALASDDHCNLKFE-AGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
             W    + + S +      E         I  V   D G Y L + N++GS+++   + +
Sbjct: 33362 WSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 20/157 (12%)

Query: 217  SRQS-VVSKQATSALQQEETSEK---KSRKVVIREKAERLSLRKTLEETETYHAKLNEDH 272
            SR S +++ +AT+    + TS     K  K ++ E+++    RK L+  E      +E  
Sbjct: 1769 SRDSGIITCRATNKYGTDHTSATLIVKDEKSLV-EESQLPEGRKGLQRIEELERMAHEGA 1827

Query: 273  LL---------HAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANP 323
            L            P+ ++ P    V E E  +  C + G+P+P+V WY N   I      
Sbjct: 1828 LTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKR- 1886

Query: 324  GKYIIESRY-GMHTLEINGCDFEDTAQYRASAMNVKG 359
                   RY G+H L+I  C   DT + + +A N +G
Sbjct: 1887 ----FRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEG 1919



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P FI + +   V +  +V+L C + G P   VTW KN   I    +  KY +  R  +  
Sbjct: 4955 PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIR---SSKKYTLTDRVSVFN 5011

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            L I  CD  DT +Y+    N  G  S    V +K
Sbjct: 5012 LHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK 5045



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 93/463 (20%), Positives = 166/463 (35%), Gaps = 72/463 (15%)

Query: 1114  RVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSK 1173
             RV A+  +   K + L G        G  +    V+ D VI    +C+     +   W K
Sbjct: 11999 RVEAMGMSSEAKLTVLEGDPYFT---GKLQDYTGVEKDEVI---LQCEISKADAPVKWFK 12052

Query: 1174  DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLL 1233
             D    + S    +++ G K  +  K     D+G Y+CD   TD  +    I++ E+K + 
Sbjct: 12053 DGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD-CGTDKTSGKLDIEDREIKLVR 12111

Query: 1234  ALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMH 1293
              L               +VE++E    RF  + E    +   N+    + + + P     
Sbjct: 12112 PLH--------------SVEVMETETARF--ETEISEDDIHANWKLKGEALLQTP--DCE 12153

Query: 1294  IDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTV-VLVGDVFKKLQKEAEFQRQEW 1352
             I     I  + +   + +  G   FQ  + K++ H  V   V  + + L+          
Sbjct: 12154 IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVT------- 12206

Query: 1353  IRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICT 1412
                            VT        C+++   ++  + WY   +++   +K         
Sbjct: 12207 ---------------VTAGETATFDCELS--YEDIPVEWYLKGKKLEPSDK--------- 12240

Query: 1413  LLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSAT-DLKIQST 1471
                    + +  ++ + L+D + +D   ++L  + FK       K+  +  T  L+ Q+ 
Sbjct: 12241 ----VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTV 12296

Query: 1472  AEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
              EG           E+ KV W  NG+ I  S + +    G    L I++ TP D   Y  
Sbjct: 12297 EEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 12356

Query: 1532  ELFDGKTGHQKTVDLSGQAYDEAYAEFQR-LKQAAIAEKNRAR 1573
             +  D KT     V          + EF R L    + EK  AR
Sbjct: 12357 DAKDFKTSCNLNV-------VPPHVEFLRPLTDLQVREKEMAR 12392



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 56/244 (22%), Positives = 92/244 (37%), Gaps = 39/244 (15%)

Query: 273  LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY 332
            +L     + KP S  V   +   L C++AG PE    W+K+   +    +  KY I    
Sbjct: 7582 VLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKEL---TSDNKYKISFFN 7638

Query: 333  GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF 392
             +  L+I      D+  Y     N  G+ S  AS+ V                 T+P S 
Sbjct: 7639 KVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV--------------SDRTVPPS- 7683

Query: 393  GVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSP 452
                          F  K   + G  G ++ + C+V  +P I      + W+  G  +S 
Sbjct: 7684 --------------FTRKLKETNGLSGSSVVMECKVYGSPPI-----SVSWFHEGNEISS 7724

Query: 453  SKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAA 512
             +  QT  +     LT + L + D G YT         ++ SA + VR+  + ++     
Sbjct: 7725 GRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQ--KPD 7782

Query: 513  PLDV 516
            P+DV
Sbjct: 7783 PMDV 7786



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 109/563 (19%), Positives = 209/563 (37%), Gaps = 91/563 (16%)

Query: 1121 AGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNF-ECDKMTPKSEFSWSKDYVSTE 1179
            A V    + +  +  +  P  ++   +V+    +SL F    + TP  +  W K      
Sbjct: 6816 ANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELV 6875

Query: 1180 DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS--SYLIDEEE---LKRLLA 1234
                  +  +   T++   ++   + G YSC VT+  G AS  ++L  +E    +KRL  
Sbjct: 6876 PGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLAD 6935

Query: 1235 LSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHI 1294
             S E   P V       +E    G           +    V++I +E  I +  +  + +
Sbjct: 6936 FSVETGSPIV-------LEATYTG-----------TPPISVSWIKDEYLISQSERCSITM 6977

Query: 1295 DRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIR 1354
               + I+E+    ++D  + +   + + G+    + V ++                    
Sbjct: 6978 TEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVL-------------------- 7017

Query: 1355 KQGPHFVEYLSW--EVTGECNVLLKCKVANIKKETHIVWYKDEREI--SVDEKHDFKDGI 1410
             + P+F+E L     V GE    L+CKV     E  I WYK+  ++  +   K  FK+ +
Sbjct: 7018 -EPPYFIEPLEHVEAVIGE-PATLQCKVDGTP-EIRISWYKEHTKLRSAPAYKMQFKNNV 7074

Query: 1411 CTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEA------FKELMMEVCKKIALS-A 1463
             +L+I +    D G Y     +  G   S   LV +A      F   + +V + +    A
Sbjct: 7075 ASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVA 7134

Query: 1464 TDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTP 1523
             + +I  +              E L+V+W  +G  ++    ++T        LQI +   
Sbjct: 7135 FECRINGS--------------EPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQ 7180

Query: 1524 NDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVT 1583
            +  G+Y          +    +  G A   A        +  ++E          P  V 
Sbjct: 7181 SHIGQY----------NCSASNPLGTASSSA--------KLILSEHEVPPFFDLKPVSVD 7222

Query: 1584 IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
            +  G++    C+V G  P +++W K+ + +    +  +      TA  T+  V   D+G+
Sbjct: 7223 LALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTL-VENTATLTVLKVGKGDAGQ 7281

Query: 1644 YGLVVKNKYGSETSDFTVSVFIP 1666
            Y     N  G ++    + V  P
Sbjct: 7282 YTCYASNIAGKDSCSAQLGVQEP 7304



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 96/436 (22%), Positives = 168/436 (38%), Gaps = 62/436 (14%)

Query: 1100 LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFE 1159
            L +R +    S    V+AIN AG             +    T+E+   V  +      FE
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFE 2195

Query: 1160 CDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIA 1219
            C+   P  +  W KD +   +  +  + S      ++   +   D   YSC + + + + 
Sbjct: 2196 CETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVK 2255

Query: 1220 SSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILE--KGQVRFWMQAEKLSGNAKVNY 1277
            ++         +L+      +F    VK    +E+ E   G++   +  E + G     +
Sbjct: 2256 TT--------AKLIVEGAVVEF----VKELQDIEVPESYSGELECIVSPENIEG----KW 2299

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDV 1337
              N+ E+    KY   I    G   + ++ +  ED+G Y+F + DGK T           
Sbjct: 2300 YHNDVELKSNGKYT--ITSRRGRQNLTVKDVTKEDQGEYSFVI-DGKKTT---------- 2346

Query: 1338 FKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVL-LKCKVANIKKETHIVWYKDER 1396
              KL+          ++ +    ++ LS +   E +++ L+ KV+   +    VW KD +
Sbjct: 2347 -CKLK----------MKPRPIAILQGLSDQKVCEGDIVQLEVKVS--LESVEGVWMKDGQ 2393

Query: 1397 EIS-VDEKHDFKDGIC-TLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMME 1454
            E+   D  H   D     LLI + +K+DAG Y   +         R+ +         ++
Sbjct: 2394 EVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-------VD 2446

Query: 1455 VCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDL-KVNWSHNGSAIRYSDRVKTGVTGEQ 1513
            V        T LK  +  EG +        V D+  V W  N   I+  DRV+  V G +
Sbjct: 2447 V-------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTK 2499

Query: 1514 IWLQINEPTPNDKGKY 1529
              L IN    +D+G Y
Sbjct: 2500 QRLVINRTHASDEGPY 2515



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 115/564 (20%), Positives = 203/564 (35%), Gaps = 88/564 (15%)

Query: 1090  LNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD 1149
             L E   + + ++   L++  +Y  R+ +    G  K  +LA   ++  +P   E++    
Sbjct: 12511 LTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFIS--KPQNLEILEGEK 12568

Query: 1150  DDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYS 1209
              + V S++ E   +       W +D  + E   + +V + G K  +  KD  + D+G Y 
Sbjct: 12569 AEFVCSISKESFPV------QWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYV 12622

Query: 1210  CDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKL 1269
               V      A   +I++  +              VP+K      + E+ +V F    E  
Sbjct: 12623 VMVGAARAAAHLTVIEKLRI-------------VVPLKD---TRVKEQQEVVF--NCEVN 12664

Query: 1270  SGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHS 1329
             +  AK  +  NE+ IF+  KY   I +   +  + +     +D+  Y   L + +  N  
Sbjct: 12665 TEGAKAKWFRNEEAIFDSSKYI--ILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVK 12722

Query: 1330  TVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHI 1389
             +   +    + L+     +  E + K+   F     W      NV LK            
Sbjct: 12723 SAANLIVEEEDLRIVEPLKDIETMEKKSVTF-----WCKVNRLNVTLK------------ 12765

Query: 1390  VWYKDEREISVDEKHDFKDGICTLLIT--EFSKKDAGIYEVILKDDRGKDKSRLKLVDEA 1447
              W K+  E+  D +  ++      ++T  +    D G Y V      G+DKS  +L    
Sbjct: 12766 -WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTA----GQDKSVAEL---- 12816

Query: 1448  FKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKT 1507
                L++E   +      D   Q+  E            E   V W  NG  I+   + K 
Sbjct: 12817 ---LIIEAPTEFVEHLED---QTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKF 12870

Query: 1508  GVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIA 1567
                G    L I +   +D+ +Y   + D K+  +  V       +E   E  R  Q  + 
Sbjct: 12871 EKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFV-------EEIPVEIIRPPQDILE 12923

Query: 1568  EKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGR 1627
                         DVV + E   LN           EV WL+N   +   D   +  E G+
Sbjct: 12924 APG--------ADVVFLAE---LN-------KDKVEVQWLRNNMVVVQGDKHQMMSE-GK 12964

Query: 1628  TAYFTINGVSTADSGKYGLVVKNK 1651
                  I  +   D G+Y  + K+K
Sbjct: 12965 IHRLQICDIKPRDQGEYRFIAKDK 12988



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 44/200 (22%), Positives = 83/200 (41%), Gaps = 11/200 (5%)

Query: 1484  YVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKT 1543
             Y +  +V W      +  S++ +         L + + T  D G Y  ++ +        
Sbjct: 31594 YDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSY 31653

Query: 1544  VDLSGQAYDEAYAEFQRLKQAAIAEK-NRARVLGGLPDVV------TIQEGKALNLTCNV 1596
              +L  +   E Y  + R     I  + +  R+L   P+        T   G+ +     +
Sbjct: 31654 AELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTI 31713

Query: 1597  WGDPPPEVSWLKN-EKALASDDHCNLKFEAGRTAY-FTINGVSTADSGKYGLVVKNKYGS 1654
                P P V+W K+ +K    D+     FE+ +  Y  TIN V+T D  +Y +V +NKYG 
Sbjct: 31714 TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE 31773

Query: 1655  ET--SDFTVSVFIPEEEARM 1672
             ++  +  TV++  P  ++ +
Sbjct: 31774 DSCKAKLTVTLHPPPTDSTL 31793



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 49/207 (23%), Positives = 79/207 (38%), Gaps = 35/207 (16%)

Query: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
           AP F    +S  V E         I+G+P P V+W+++   I+    PG  I  S  G  
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSD-GRA 63

Query: 336 TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVT 395
            L I      ++ +Y   A N  G+ ++ A ++VK              A T P      
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK--------------AETAP------ 103

Query: 396 PYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKW 455
                     +F  +      R+G  + L  RV   P      P +++YR+G  +  S  
Sbjct: 104 ---------PNFVQRLQSMTVRQGSQVRLQVRVTGIP-----TPVVKFYRDGAEIQSSLD 149

Query: 456 VQTLWSGERATLTFSHLNKEDEGLYTI 482
            Q    G+  +L  +    ED G Y++
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSV 176



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 2/90 (2%)

Query: 1575  LGGLPDVVTI-QEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTI 1633
             L GLPD+  + +E     L   + G P P VSW K E  LA+D   +++  A  T    +
Sbjct: 19984 LKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTT-LIV 20042

Query: 1634  NGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
                  +D+GKY + +KN  G++    ++ V
Sbjct: 20043 YDCQKSDAGKYTITLKNVAGTKEGTISIKV 20072



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 4/95 (4%)

Query: 277  PEFIIK-PRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
            P F+ K   S+ +   E+ +LHC + G P  +VTW+KN   ++       Y + S     
Sbjct: 3737 PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSE---A 3793

Query: 336  TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
             L+I     ED+  Y   A+N  G  S    +V+K
Sbjct: 3794 ILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIK 3828



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 112/499 (22%), Positives = 178/499 (35%), Gaps = 92/499 (18%)

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             FEC+       F W K         R E+   G K  M  K    +D   Y  +  D   
Sbjct: 11859 FECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH- 11917

Query: 1218  IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
              +   +I+   LK L            P+K    V   EK    F    E    N +V +
Sbjct: 11918 TSGKLIIEGIRLKFL-----------TPLKD---VTAKEKESAVF--TVELSHDNIRVKW 11961

Query: 1278  IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDV 1337
               N++ +       M  +  T  I    + L  +D      +   G ++     VL GD 
Sbjct: 11962 FKNDQRLHTTRSVSMQDEGKTHSIT--FKDLSIDDTSQIRVEAM-GMSSEAKLTVLEGDP 12018

Query: 1338  F--KKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDE 1395
             +   KLQ     ++ E                      V+L+C+++  K +  + W+KD 
Sbjct: 12019 YFTGKLQDYTGVEKDE----------------------VILQCEIS--KADAPVKWFKDG 12054

Query: 1396  REISVDEKHDFK-DGICTLLITEFS-KKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1453
             +EI   +    K DG   +LI + + K D G Y      D G DK+  KL D   +E+  
Sbjct: 12055 KEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKL-DIEDREI-- 12107

Query: 1454  EVCKKIALSATDLKIQSTAEGIQLYSFVTYYVE-DLKVNWSHNGSAIRYSDRVKTGVTGE 1512
                 K+      +++  T    +   F T   E D+  NW   G A+             
Sbjct: 12108 ----KLVRPLHSVEVMET----ETARFETEISEDDIHANWKLKGEAL------------- 12146

Query: 1513  QIWLQINEPTPNDKGK-YVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR 1571
                LQ  +    ++GK + + L + +      VD   QA +   +   R+K   I     
Sbjct: 12147 ---LQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANVKSSAHLRVKPRVIG---- 12197

Query: 1572  ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYF 1631
               +L  L D VT+  G+     C +  +  P V W    K L   D    + E G+    
Sbjct: 12198 --LLRPLKD-VTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSE-GKVHTL 12252

Query: 1632  TINGVSTADSGKYGLVVKN 1650
             T+  V   D+G+  L  K+
Sbjct: 12253 TLRDVKLEDAGEVQLTAKD 12271



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 2/95 (2%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             V  + G+ + +     G PPP V+W K+EK L SD   +++     ++  TI  V+  D+
Sbjct: 27281 VIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDT 27339

Query: 1642  GKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALE 1676
             GKY L ++N  G E    TVSV + +  A    L+
Sbjct: 27340 GKYILTIENGVG-EPKSSTVSVKVLDTPAACQKLQ 27373



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 34/122 (27%), Positives = 61/122 (50%), Gaps = 7/122 (5%)

Query: 1544  VDLSGQA-YDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPP 1602
             V++ G + Y E+ AE + +++  I +   A     L   VTI+ G +L L  +V G PPP
Sbjct: 29420 VNVKGMSEYSESIAEIEPVERIEIPDLELA---DDLKKTVTIRAGASLRLMVSVSGRPPP 29476

Query: 1603  EVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVS 1662
              ++W K    LAS    +        +   ++ V+  D+GKY +  +N+ G +++   V 
Sbjct: 29477 VITWSKQGIDLASRAIID---TTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 29533

Query: 1663  VF 1664
             V+
Sbjct: 29534 VY 29535



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 152/790 (19%), Positives = 286/790 (36%), Gaps = 153/790 (19%)

Query: 997  KISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLV 1056
            KIS  K    Y+  +A   +A L     +S     ++ T +V  P  ++K SE R     
Sbjct: 820  KISVPKTEHGYEASIAGSAIATL--QKELSATSSAQKITKSVKAP--TVKPSETR----- 870

Query: 1057 LQWKPPVHSGRTPVTGY-FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRV 1115
                  V +  TP+  + F D  +    E       E  +      VR  +  V +    
Sbjct: 871  ------VRAEPTPLPQFPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREA 924

Query: 1116 RAINQAGVGKPSDLAGPVVAETR-PGTKEVVVNVDDDGVISLNFECD-KMTPKSEFSWSK 1173
            +    A V  P ++  PV   T   G K V V   +    S+  EC     P    +W +
Sbjct: 925  KVTETARVPAPVEI--PVTPPTLVSGLKNVTVIEGE----SVTLECHISGYPSPTVTWYR 978

Query: 1174 DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS--YL---IDEE- 1227
            +    E S   ++  +    ++  ++   +D G ++C   +  G  S+  YL   + EE 
Sbjct: 979  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF 1038

Query: 1228 -------------ELKRLL----------ALSHEHKFPTVP-----VKSELAVEILEKGQ 1259
                         E KR +          +L+ E   P  P     +   +  +++E G 
Sbjct: 1039 EKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGS 1098

Query: 1260 VRFWMQAEKLSGNAKVNYIFNEKEI--FEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
            V F  Q   + GN K +  + +  +    G +YK+  ++ TG  ++ +     +D G YT
Sbjct: 1099 VVFGCQ---VGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYT 1155

Query: 1318 FQLQDGKATNHSTVVLVGD----VFKKLQKEAEFQRQEWIRKQGPHFVE------YLSWE 1367
              +++      ++  L+ +    +  K Q+E  +Q Q     Q P   E      Y  +E
Sbjct: 1156 IVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYE 1215

Query: 1368 VTGECN-VLLKCKVANIKKETHIV-WYKDEREISVDEKHDFKDGICTLLITEFSKKDAGI 1425
               E    L++ K+A   K+T +V  Y +++E  +     F++ +   +     K     
Sbjct: 1216 KEYEKEQALIRKKMA---KDTVVVRTYVEDQEFHISS---FEERLIKEIEYRIIKTTL-- 1267

Query: 1426 YEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQS----TAEGIQLYSFV 1481
             E +L++D G++K  + + +    E           S  D +I++       G+  +  +
Sbjct: 1268 -EELLEED-GEEKMAVDISESEAVE-----------SGFDSRIKNYRILEGMGVTFHCKM 1314

Query: 1482 TYYVEDLKVNWSHNGSAIRYSDRVKTGVTGE-QIWLQINEPTPNDKGKYVM--------E 1532
            + Y    K+ W  +G  I++ +R +     + +  L+I    P D+G Y           
Sbjct: 1315 SGYPLP-KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNA 1373

Query: 1533 LFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR--------------------- 1571
            +  GK   +    L    Y        R++  +    +R                     
Sbjct: 1374 ICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMS 1433

Query: 1572 -ARVLGGL---------------------PDVVTIQEGKALNLTCNVWGDPPPEVSWLKN 1609
             AR+  G                      P      EG+       V G P PE  W  +
Sbjct: 1434 PARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHD 1493

Query: 1610 EKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEE 1669
             + + +D    +  +   T    I   + +DSG++ +V +N+ G  +    ++V   E +
Sbjct: 1494 GQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQ 1553

Query: 1670 ARMAALESLK 1679
             +   +E LK
Sbjct: 1554 VKPMFVEKLK 1563



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 4/95 (4%)

Query: 277  PEFIIKPR-SHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
            P FI K   S  V + E  +  C I G PE +V WYK++  I   +      ++S   + 
Sbjct: 7305 PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDS---VA 7361

Query: 336  TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
             LE++    ED+  Y   A N  G  S+  S+ VK
Sbjct: 7362 VLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 86/408 (21%), Positives = 152/408 (37%), Gaps = 50/408 (12%)

Query: 1155 SLNFECDKM-TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVT 1213
            S +FEC    T   + SW+KD        + ++    N   +T   +   D G Y+C   
Sbjct: 8169 SADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTC--- 8225

Query: 1214 DTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
                    Y ++E       A  +  +    P  ++   E +E+ +   +    +++G+ 
Sbjct: 8226 --------YAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQ 8277

Query: 1274 KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD--GKATNHSTV 1331
             +   + +  I   P     I      + + + K    D G YT ++ +  G A   S++
Sbjct: 8278 PITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSI 8337

Query: 1332 VLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECN-VLLKCKVANIKKETHIV 1390
            V+         KE          K+ P F ++L+     E   V L C V    +   I 
Sbjct: 8338 VI---------KEP---------KKPPVFDQHLTPVTVSEGEYVQLSCHVQG-SEPIRIQ 8378

Query: 1391 WYKDEREISVDEK--HDFKDGICTLLITEFSKKDAGIYEVILKDDRGKD--KSRLKLVDE 1446
            W K  REI   ++    F  G   L + + +K D+G Y     +  G D  KS++ + D 
Sbjct: 8379 WLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKD- 8437

Query: 1447 AFKELMMEVCKKIALSATDLKIQSTAEGIQLY-----SFVTYYVED--LKVNWSH-NGSA 1498
              K  +    KK A+    L   S  + I++      +F+     D    V W+      
Sbjct: 8438 --KPAVAPATKKAAVDGR-LFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQ 8494

Query: 1499 IRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDL 1546
            +    RV     G++  L+I + T  D G Y    F+     +  V+L
Sbjct: 8495 LNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNL 8542



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 41/205 (20%), Positives = 77/205 (37%), Gaps = 33/205 (16%)

Query: 1358  PHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFK---DGICTLL 1414
             P   ++L  E + E   L     +++ +   + WYKD +++  +    F    DG   L 
Sbjct: 32718 PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 32777

Query: 1415  ITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTA-- 1472
             I   ++ D G Y   +  + G  K+ L+ + +AFK +  +V K      +D K   +   
Sbjct: 32778 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVT 32837

Query: 1473  --------EGIQLYSFVTYYVEDLKVN--------------------WSHNGSAIRYSDR 1504
                     E I     +   ++D  V+                    W+ +G AI    +
Sbjct: 32838 RKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGK 32897

Query: 1505  VKTGVTGEQIWLQINEPTPNDKGKY 1529
              K        +L+I++   +D G Y
Sbjct: 32898 YKLSEDKGGFFLEIHKTDTSDSGLY 32922



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 64/306 (20%), Positives = 122/306 (39%), Gaps = 34/306 (11%)

Query: 184   STASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKV 243
             S++ K T  + + T +++ +  K S  + Q  A  Q  +S++A  + + + +  K   K+
Sbjct: 32934 SSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKL 32993

Query: 244   VIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGW 303
              ++E+A ++ +    EE +   A   E  ++H  E I K    T    E V+ H  I   
Sbjct: 32994 ALKEEASKVLIS---EEVKKSAATSLEKSIVH--EEITK----TSQASEEVRTHAEIKA- 33043

Query: 304   PEPRVTWYKNQVPINVHANPGKYIIESRYGMHT---LEINGCDFEDTAQYRASAMNVKGE 360
                    +  Q+ IN      + ++++     T     +NG +  ++ +YR         
Sbjct: 33044 -------FSTQMSIN---EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYG------- 33086

Query: 361   LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGE 420
             +S     +  +     DE      + T     G+    Y         D          +
Sbjct: 33087 VSGSDQTLTIKQASHRDEGILTCISKTKE---GIVKCQYDLTLSKELSDAPAFISQPRSQ 33143

Query: 421   TMSLGCRVVITPEIK-HFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 479
              ++ G  V+ T EI     PEI+W++N +P+S S  V    S    +L   + +  D G 
Sbjct: 33144 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 33203

Query: 480   YTIRVR 485
             YTI+ +
Sbjct: 33204 YTIKAK 33209



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 46/190 (24%), Positives = 78/190 (41%), Gaps = 28/190 (14%)

Query: 1492 WSHNGSAI--RYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQ 1549
            W H+G  I   Y+ +V     G Q  L I   TP+D G++ +   +       +V L+ +
Sbjct: 1490 WFHDGQQIVNDYTHKVVIKEDGTQS-LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1548

Query: 1550 AYDEAYAEF--QRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWL 1607
            A +        ++LK                   V I+EG  L +     G+P P++ WL
Sbjct: 1549 AVEHQVKPMFVEKLKN------------------VNIKEGSRLEMKVRATGNPNPDIVWL 1590

Query: 1608 KNEKALASDDHCNLKFEAGR-TAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFI- 1665
            KN   +    +  ++ E  +  A   I+   + DS  Y     NK G +T+   V+V + 
Sbjct: 1591 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1650

Query: 1666 ---PEEEARM 1672
               PE E ++
Sbjct: 1651 FAEPEPERKL 1660



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 4/95 (4%)

Query: 277  PEFIIKPRSHTVWEK-ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
            P+F+ K  +  V ++ E+++L C I+G PE +V+W++N   ++      KY +     + 
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELH---ESWKYNMSFINSVA 6420

Query: 336  TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
             L IN    ED+  Y   A N  G+ S   ++ VK
Sbjct: 6421 LLTINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 60/252 (23%), Positives = 86/252 (34%), Gaps = 40/252 (15%)

Query: 266  AKLNEDHLLHAPEFIIKPRSHTVWEKE--NVKLHCSIAGWPEPRVTWYKNQVPINVHANP 323
            A+LN    L  P F  K  S TV E E  + KL   +AG     V WYKN + I   +N 
Sbjct: 8238 AQLNIKERLIPPSFT-KRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSN- 8295

Query: 324  GKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHA 383
                I  +     L++      D   Y     N  G     +S+V+K  K          
Sbjct: 8296 --CEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPK---------- 8343

Query: 384  GASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQW 443
                 P+                FD         EGE + L C V  +  I+     IQW
Sbjct: 8344 ---KPPV----------------FDQHLTPVTVSEGEYVQLSCHVQGSEPIR-----IQW 8379

Query: 444  YRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDAD 503
             + G  + PS      ++   A L    + K D G Y  +       +   + V ++D  
Sbjct: 8380 LKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKP 8439

Query: 504  AEIEGAPAAPLD 515
            A       A +D
Sbjct: 8440 AVAPATKKAAVD 8451



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 8/97 (8%)

Query: 277  PEFIIK-PRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPG--KYIIESRYG 333
            P+F+ K   S  V   ++ +L C IAG PE RV W++N+     H  P   KY +     
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNE-----HELPASDKYRMTFIDS 5477

Query: 334  MHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            +  +++N    ED+  +   A N  G  S    V+VK
Sbjct: 5478 VAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 5514



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 5/65 (7%)

Query: 419  GETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEG 478
            G+++SL C+V  TPEI      + WY+    L P+   +T ++   ATL F+ +N  D G
Sbjct: 6093 GDSVSLQCQVAGTPEIT-----VSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSG 6147

Query: 479  LYTIR 483
             YT +
Sbjct: 6148 EYTCK 6152



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 5/91 (5%)

Query: 1582 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD--DHCNLKFEAGRTAYFTINGVSTA 1639
            V + EG       ++ G P PEVSW ++ + +++       + F  GR A  TI  V+ A
Sbjct: 15   VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR-AKLTIPAVTKA 73

Query: 1640 DSGKYGLVVKNKYGSETSDFTVSVFIPEEEA 1670
            +SG+Y L   N  G  TS  T  + +  E A
Sbjct: 74   NSGRYSLKATNGSGQATS--TAELLVKAETA 102



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 72/366 (19%), Positives = 128/366 (34%), Gaps = 61/366 (16%)

Query: 136  YMVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQ 195
            + V  F G ++ V G  D      ++  A +   N+  S+ G  T   S  + Q + + +
Sbjct: 5922 FKVNWFRGARELVKG--DRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTR 5979

Query: 196  STASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLR 255
                K+  A  +  +       +  ++    T  L    T +K    +   EK   ++  
Sbjct: 5980 LFV-KEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTE 6038

Query: 256  KTL---------EETETYHAKLNED----------HLLHAPEFIIKPRSHTVWEKENVKL 296
            KT           +   Y  ++  +            L  P F+ +         ++V L
Sbjct: 6039 KTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSL 6098

Query: 297  HCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMN 356
             C +AG PE  V+WYK    +        Y   +   + TL  N  +  D+ +Y   A N
Sbjct: 6099 QCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNN---VATLVFNKVNINDSGEYTCKAEN 6155

Query: 357  VKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFG 416
              G  S+              +T F      +P SF       A + +       D+   
Sbjct: 6156 SIGTASS--------------KTVFRIQERQLPPSF-------ARQLK-------DIE-- 6185

Query: 417  REGETMSLGCRVVITPEIKHFQP-EIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKE 475
                  ++G  V +T  +    P ++ WYR+GV L   + +QT +    ATL     +  
Sbjct: 6186 -----QTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLS 6240

Query: 476  DEGLYT 481
              G Y+
Sbjct: 6241 HSGQYS 6246



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 51/263 (19%), Positives = 95/263 (36%), Gaps = 51/263 (19%)

Query: 278  EFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYI-IESRYGMHT 336
            +F+ +   +++ + + + L  +  G P   VTW KN     ++  P +   I +      
Sbjct: 7869 KFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKN----GINVTPSQRCNITTTEKSAI 7924

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTP 396
            LEI     ED  QY     N  G+ S  A +++                          P
Sbjct: 7925 LEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE-----------------------PP 7961

Query: 397  YGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWV 456
            Y         F  + +      G++ SL C++  TPEI      + WY+    L P+   
Sbjct: 7962 Y---------FVKQLEPVKVSVGDSASLQCQLAGTPEIG-----VSWYKGDTKLRPTTTY 8007

Query: 457  QTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDAD---------AEIE 507
            +  +    ATL F+ ++  D G Y  +          S ++ V++            +++
Sbjct: 8008 KMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQ 8067

Query: 508  GAPAAPLDVKCLEANKDYIIISW 530
                 P+   C  +  + I +SW
Sbjct: 8068 ETVGLPVVFDCAISGSEPISVSW 8090



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             DV+T++ G+ + +   V G P P+++W K  K L  +   +L  +  R     I     A
Sbjct: 17916 DVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE-LQIKEAVRA 17974

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             D GKY +  KN  G       V+V
Sbjct: 17975 DHGKYIISAKNSSGHAQGSAIVNV 17998



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  VV ++    L L   + G P PEV W K E  L   D   ++  +  T    I+ V+
Sbjct: 25113 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT--DRAQIEVTSSFTM-LVIDNVT 25169

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG+Y L ++N  GS+T+   V V
Sbjct: 25170 RFDSGRYNLTLENNSGSKTAFVNVRV 25195



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 56/255 (21%), Positives = 97/255 (38%), Gaps = 41/255 (16%)

Query: 238  KKSRKVVIREKAERLSLRKTLEETE---TYHAKLNEDHLL------HAPEFIIKPRSHTV 288
            ++  K V+  +  R+ + +T +      T+ A  N   +         P+ + + +  TV
Sbjct: 3191 QERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTV 3250

Query: 289  WEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTA 348
               +  +    I+G P+P+++WYK +  ++      K++ + +   +TL +     ED A
Sbjct: 3251 QSGKPARFCAVISGRPQPKISWYKEEQLLST-GFKCKFLHDGQ--EYTLLLIEAFPEDAA 3307

Query: 349  QYRASAMNVKG--ELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
             Y   A N  G    SA  SV V        E   +  A   PL   VT  G  +RF+  
Sbjct: 3308 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQ-- 3365

Query: 407  FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                               CRV  T        ++ WY     + PS++ +     +   
Sbjct: 3366 -------------------CRVSGT------DLKVSWYSKDKKIKPSRFFRMTQFEDTYQ 3400

Query: 467  LTFSHLNKEDEGLYT 481
            L  +    EDEG YT
Sbjct: 3401 LEIAEAYPEDEGTYT 3415



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 110/529 (20%), Positives = 206/529 (38%), Gaps = 75/529 (14%)

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            TP+ +  W KD      S +  +  K N  ++ F    + D G Y+ ++++  G +SS  
Sbjct: 4043 TPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVG-SSSCE 4101

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA--KVNYIFNE 1281
                 L R +A      F T P+++   V+ +  G  R      K++G+   +V++  + 
Sbjct: 4102 TTFTVLDRDIA-----PFFTKPLRN---VDSVVNGTCRLDC---KIAGSLPMRVSWFKDG 4150

Query: 1282 KEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKL 1341
            KEI    +Y++     T  +E+   ++   D G +T +  +   +  S+  L+      +
Sbjct: 4151 KEIAASDRYRIAFVEGTASLEII--RVDMNDAGNFTCRATNSVGSKDSSGALI------V 4202

Query: 1342 QKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDERE-ISV 1400
            Q+   F     + K G       S +V     V LK         T I W+K  +E +S 
Sbjct: 4203 QEPPSF-----VTKPG-------SKDVLPGSAVCLKSTFQGSTPLT-IRWFKGNKELVSG 4249

Query: 1401 DEKHDFKDGICTLLITEFSK-KDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKI 1459
               +  K+ + + L     K  D+G Y   + +  G  +    L    F +      +K+
Sbjct: 4250 GSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANL----FVKEPATFVEKL 4305

Query: 1460 ALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN 1519
              S    ++    +  QL   VT     +K+ W  N   I+ S + +         L++ 
Sbjct: 4306 EPS----QLLKKGDATQLACKVTG-TPPIKITWFANDREIKESSKHRMSFVESTAVLRLT 4360

Query: 1520 EPTPNDKGKYVMELF-DGKTGHQKTVDLSGQA--YDEAYAEFQRLKQAAIAEKNRARVLG 1576
            +    D G+Y+ E   +  + H  ++ +  ++  + + +   + LK+             
Sbjct: 4361 DVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEY------------ 4408

Query: 1577 GLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGV 1636
               DV+ + E         V G PP E++W K+   L S       F         I   
Sbjct: 4409 ---DVMLLAE---------VAGTPPFEITWFKDNTILRSGRKYK-TFIQDHLVSLQILKF 4455

Query: 1637 STADSGKYGLVVKNKYGSETSDFTVSVFIPEE-EARMAALESLKGGKKA 1684
              AD+G+Y   V N+ GS      V++  P     ++ +  SL+GG  A
Sbjct: 4456 VAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAA 4504



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 51/214 (23%), Positives = 80/214 (37%), Gaps = 51/214 (23%)

Query: 278  EFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTL 337
            + + K +S  V EK+ + L C +AG PE +V W K+          GK I+ SRY   + 
Sbjct: 5142 QIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKD----------GKQIVPSRYFSMSF 5191

Query: 338  EINGCDF-------EDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
            E N   F       +D+ QY     N  G  S  A + V                    L
Sbjct: 5192 ENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRV--------------------L 5231

Query: 391  SFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPL 450
               + P          F  K        G ++ + C+V  +  I       QW+++G  +
Sbjct: 5232 DQNIPP---------SFTKKLTKMDKVLGSSIHMECKVSGSLPIS-----AQWFKDGKEI 5277

Query: 451  SPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRV 484
            S S   + +      +L  ++L  ED   YT +V
Sbjct: 5278 STSAKYRLVCHERSVSLEVNNLELEDTANYTCKV 5311



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 53/230 (23%), Positives = 86/230 (37%), Gaps = 47/230 (20%)

Query: 294  VKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRAS 353
            V   C I G    +V+WYK+ V +   AN     +   + + TL+I   D     QY  S
Sbjct: 7133 VAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFV---HNVATLQILQTDQSHIGQYNCS 7189

Query: 354  AMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDV 413
            A N  G  S+ A +++  ++              +P  F + P               D+
Sbjct: 7190 ASNPLGTASSSAKLILSEHE--------------VPPFFDLKPV------------SVDL 7223

Query: 414  SFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLN 473
            + G  G   +  C V  T  IK     I W ++   + P    +       ATLT   + 
Sbjct: 7224 ALGESG---TFKCHVTGTAPIK-----ITWAKDNREIRPGGNYKMTLVENTATLTVLKVG 7275

Query: 474  KEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANK 523
            K D G YT           Y++ +  +D+ +   G    P  +K LE ++
Sbjct: 7276 KGDAGQYTC----------YASNIAGKDSCSAQLGVQEPPRFIKKLEPSR 7315



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 83/367 (22%), Positives = 145/367 (39%), Gaps = 60/367 (16%)

Query: 1181  SPRLEVESKGNKTKMTFKDLGMDDLG--IYSCDVTDTDGIASSYLIDEEELKRLLALSHE 1238
             SP  E++++G K  +T   + +D  G  +Y      T  I +   + E EL         
Sbjct: 11439 SPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILT---VKEIELDF------- 11488

Query: 1239  HKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNT 1298
                  VP+K    V + E+ Q RF      L+  A V +      I    K+ +  D   
Sbjct: 11489 ----AVPLKD---VTVPERRQARFECV---LTREANVIWSKGPDIIKSSDKFDIIADGKK 11538

Query: 1299  GIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGP 1358
              I+   +   Q +DEG YT +++ GK T  S  + V  +  K     E Q  +       
Sbjct: 11539 HIL--VINDSQFDDEGVYTAEVE-GKKT--SARLFVTGIRLKFMSPLEDQTVK------- 11586

Query: 1359  HFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEF 1418
                        GE    + C++++ K   H+VW+K++ ++             T+LI+  
Sbjct: 11587 ----------EGETATFV-CELSHEKM--HVVWFKNDAKLHTSR---------TVLISSE 11624

Query: 1419  SKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY 1478
              K      + +  DD  + K+++K +    +  ++E      +   D K     + I L 
Sbjct: 11625 GKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHD-KTAVEKDEITLK 11683

Query: 1479  SFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKT 1538
               V+   +D+ V W  +G  I  S +      G +  L+I +    DKG+YV +    KT
Sbjct: 11684 CEVS---KDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKT 11740

Query: 1539  GHQKTVD 1545
                 TV+
Sbjct: 11741 KANVTVE 11747



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 99/525 (18%), Positives = 179/525 (34%), Gaps = 73/525 (13%)

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            +P    SW  +        + +     N   +T   L   D G Y+C  T+  G      
Sbjct: 7708 SPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAG------ 7761

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
               +E    L +     F    V+    +++L    V F     K +    V++     E
Sbjct: 7762 --SDECSAPLTVREPPSF----VQKPDPMDVLTGTNVTF-TSIVKGTPPFSVSWFKGSSE 7814

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKA--TNHSTVVLVGDVFKKL 1341
            +  G +  + ++ +   +E+F        E T     + GKA  T H  +       K+L
Sbjct: 7815 LVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRL 7874

Query: 1342 QKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVD 1401
               +       I K  P  +E  ++  T   +V  K    N+              I+  
Sbjct: 7875 NDYS-------IEKGKPLILEG-TFTGTPPISVTWKKNGINVTPSQRC-------NITTT 7919

Query: 1402 EKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDK--SRLKLVDEAFKELMMEVCKKI 1459
            EK         L I   + +DAG Y   +++  GKD   +++ +++  +    +E  K  
Sbjct: 7920 EKS------AILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVS 7973

Query: 1460 ALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN 1519
               +  L+ Q                 ++ V+W    + +R +   K         L  N
Sbjct: 7974 VGDSASLQCQLAG------------TPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFN 8021

Query: 1520 EPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLP 1579
            +   ND G+Y+ +            ++S   +     + Q+L  +   +    +   GLP
Sbjct: 8022 QVDINDSGEYICK------AENSVGEVSASTF--LTVQEQKLPPSFSRQLRDVQETVGLP 8073

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             V            C + G  P  VSW K+ K L    +    F    TA   I     +
Sbjct: 8074 VV----------FDCAISGSEPISVSWYKDGKPLKDSPNVQTSF-LDNTATLNIFKTDRS 8122

Query: 1640 DSGKYGLVVKNKYGSETSD----FTVSVFIPEEEARMAALESLKG 1680
             +G+Y     N  GS +S      T     P  + R+A ++++ G
Sbjct: 8123 LAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVG 8167



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEA-GRTAYFTINGV 1636
             L  V+T++ G  + L   V G P PEV+W K++ A        +K +    ++ F++   
Sbjct: 18207 LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKA 18266

Query: 1637  STADSGKYGLVVKNKYGSETSDFTVSV 1663
               +D GKY +   N  GS  +  TV+V
Sbjct: 18267 KRSDGGKYVVTATNTAGSFVAYATVNV 18293



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 5/116 (4%)

Query: 1552  DEAYAEFQRLKQAAIAEKNR----ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWL 1607
             D  Y+E +    + I ++ +    A + G    ++T + G    +   + G P P+V+W 
Sbjct: 28623 DAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWK 28682

Query: 1608  KNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               E  L   D  ++     RT   T+      DSG+Y L ++N  G +T   TV V
Sbjct: 28683 LEEMRLKETDRVSITTTKDRTT-LTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 28737



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 62/262 (23%), Positives = 104/262 (39%), Gaps = 55/262 (20%)

Query: 225  QATSALQQEETSEKKSRKVVIREKAERLSLRKTLEETETY-HAKLNEDHLLHAPEFIIKP 283
            QA   L+Q +  E    ++   E++ER    K  EE  ++   +L++      P  +IK 
Sbjct: 8608 QAFELLKQSQEEETHRLEIEEIERSERDE--KEFEELVSFIQQRLSQTE----PVTLIKD 8661

Query: 284  -RSHTVWEKENVKLHCSIA-GWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEING 341
              + TV +  +      I   +PE +++WYK    +       K+ I      HTL +  
Sbjct: 8662 IENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPS---DKFEISIDGDRHTLRVKN 8718

Query: 342  CDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYAS 401
            C  +D   YR     V G   A A + V                        + P     
Sbjct: 8719 CQLKDQGNYRL----VCGPHIASAKLTV------------------------IEP----- 8745

Query: 402  RFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS 461
             +E H  D   V+  +EG+T ++ C+  + P +K      +W+RNG  L P    +T   
Sbjct: 8746 AWERHLQD---VTL-KEGQTCTMTCQFSV-PNVKS-----EWFRNGRILKPQGRHKTEVE 8795

Query: 462  GERATLTFSHLNKEDEGLYTIR 483
             +   LT + +  ED+G YT +
Sbjct: 8796 HKVHKLTIADVRAEDQGQYTCK 8817



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G+   L  +V G P P + WL+ +K +     C +K      A   +      
Sbjct: 23633 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIRI 23691

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             D G+Y L   N  GS++    V V
Sbjct: 23692 DGGQYILRASNVAGSKSFPVNVKV 23715



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 1/94 (1%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P F+ K ++  + E   +++     G P P + W KN   I  H  P K  IE   G   
Sbjct: 1556 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYP-KIRIEGTKGEAA 1614

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            L+I+    +D+A Y A+A+N  G  +    V V+
Sbjct: 1615 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 4/95 (4%)

Query: 277  PEFIIKPRSHTVWEK-ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
            P+FI KP    V    ++    C I G P+ RV+WY +   I      G   I+   G+ 
Sbjct: 4861 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFID---GLA 4917

Query: 336  TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            T +I+G   E++  Y   A N  G  S    + VK
Sbjct: 4918 TFQISGARVENSGTYVCEARNDAGTASCSIELKVK 4952



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 72/365 (19%), Positives = 133/365 (36%), Gaps = 62/365 (16%)

Query: 124   LSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKE----AAAYIAQRNLLASEEGIT 179
             L G++ E  PSD +VP   G+  H   + D + E   E    A  +    NL   E  + 
Sbjct: 12230 LKGKKLE--PSDKVVPRSEGKV-HTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVE 12286

Query: 180   TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
              +K           +  T  + +TA  +   SR++   +      +   + + E  ++ +
Sbjct: 12287 FTKPL---------EDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGR 12337

Query: 240   SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
              RK+VI +      ++    + + +    N + +    EF+       V EKE  +  C 
Sbjct: 12338 VRKLVIHDCTPE-DIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECE 12396

Query: 300   IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
             ++     +V W+K+   I       KY I S+  +  L IN C  +D A+Y       + 
Sbjct: 12397 LSR-ENAKVKWFKDGAEIK---KGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTAR- 12451

Query: 360   ELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREG 419
               S   +V+        +E  F    + + +S                          E 
Sbjct: 12452 -TSGMLTVLE-------EEAVFTKNLANIEVS--------------------------ET 12477

Query: 420   ETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 479
             +T+ L C      E+     E+ WY+    +  +   + L  G +  L   + + ED G 
Sbjct: 12478 DTIKLVC------EVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 12531

Query: 480   YTIRV 484
             Y  R+
Sbjct: 12532 YNCRL 12536



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 2/84 (2%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D++ I EG+ L++       P P VSW K+ K + + D   +K +   +A+  +     A
Sbjct: 14395 DIIVI-EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKND-HISAHLEVPKSVRA 14452

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             D+G Y + ++NK GS T+   V V
Sbjct: 14453 DAGIYTITLENKLGSATASINVKV 14476



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 50/209 (23%), Positives = 82/209 (39%), Gaps = 25/209 (11%)

Query: 286   HTVWEKE-NVKLHCSIAGWPEP-RVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
             H V E+  +VK  C I  + +  +VTWY     +    N  KY I    G+  L +    
Sbjct: 31576 HAVGEEGGHVKYVCKIENYDQSTQVTWYFG---VRQLENSEKYEITYEDGVAILYVKDIT 31632

Query: 344   FEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASR- 402
               D   YR   +N  GE S+YA + VK  +  +D   ++   +   +           R 
Sbjct: 31633 KLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYD---YYCRRTMKKIKRRTDTMRLLERP 31689

Query: 403   --FEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSP----SKWV 456
               F +   +K        GE +  G  + + PE     P + WY++G  + P     K+ 
Sbjct: 31690 PEFTLPLYNK----TAYVGENVRFGVTITVHPE-----PHVTWYKSGQKIKPGDNDKKYT 31740

Query: 457   QTLWSGERATLTFSHLNKEDEGLYTIRVR 485
                  G    LT + +  +D+  YT+  R
Sbjct: 31741 FESDKG-LYQLTINSVTTDDDAEYTVVAR 31768



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G++  +  +++G P P + W+K ++ L++     +K     T+  ++      
Sbjct: 22551 DTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATS-LSVKDAVRV 22609

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             DSG Y L  KN  G  +    V V
Sbjct: 22610 DSGNYILKAKNVAGERSVTVNVKV 22633



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 5/96 (5%)

Query: 290   EKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQ 349
             E ++V     ++G P P + W K+  P+++   P   II      + L I     EDT  
Sbjct: 31808 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSL--GPNIEIIHEGLDYYALHIRDTLPEDTGY 31865

Query: 350   YRASAMNVKGELSAYASVVVKRY---KGEFDETRFH 382
             YR +A N  G  S  A + V+R    K EF     H
Sbjct: 31866 YRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEH 31901



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 51/214 (23%)

Query: 278  EFIIKPRSHTVWEKENVK--------LHCSIAGWPEPRVTWYKNQVPINVHANPGK-YII 328
            E II  + H + E E V+        L C +    +  VTW K+   +     PGK Y I
Sbjct: 3637 ELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLP----PGKDYKI 3692

Query: 329  ESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTM 388
                 + TLEI     +D+  Y  +A N  G  S  A+V V+                  
Sbjct: 3693 CFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE----------------- 3735

Query: 389  PLSFGVTPYGYASRFEIHFDDKFDVSFGR-EGETMSLGCRVVITPEIKHFQPEIQWYRNG 447
            P SF                 K D S+    GE+  L C++  +P I     ++ W++N 
Sbjct: 3736 PPSFV---------------KKVDPSYLMLPGESARLHCKLKGSPVI-----QVTWFKNN 3775

Query: 448  VPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYT 481
              LS S  V+  +    A L  + +  ED G Y+
Sbjct: 3776 KELSESNTVRMYFVNSEAILDITDVKVEDSGSYS 3809



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 30/121 (24%), Positives = 54/121 (44%), Gaps = 14/121 (11%)

Query: 419  GETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEG 478
            GET +L C+V  TPE+      ++WY++G  L+ S+  +  +  + ++L    + ++D G
Sbjct: 5718 GETCTLECKVAGTPELS-----VEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAG 5772

Query: 479  LYTIRVRMGEYYEQYSAYVFVRDADA---------EIEGAPAAPLDVKCLEANKDYIIIS 529
             YT +V+        +A V V D               G   A   ++C  A    I ++
Sbjct: 5773 TYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVA 5832

Query: 530  W 530
            W
Sbjct: 5833 W 5833



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 1/81 (1%)

Query: 1583  TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
             +IQ G+ L +   V G P P +SW+K+ + L      N++  A  T      G +  D G
Sbjct: 24322 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEG-NKDDFG 24380

Query: 1643  KYGLVVKNKYGSETSDFTVSV 1663
             KY +   N  G+ T + +V V
Sbjct: 24381 KYTVTATNSAGTATENLSVIV 24401



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 104/521 (19%), Positives = 194/521 (37%), Gaps = 76/521 (14%)

Query: 1155 SLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTD 1214
            ++ FE         + W K+ V  + + + ++ +K     +  +++   D    + D T 
Sbjct: 2985 TITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGD----AADYTF 3040

Query: 1215 TDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAK 1274
              G A+S      E + +    H        +K    +++LEK +  F  + E    +  
Sbjct: 3041 VAGKATSTATLYVEARHIEFRKH--------IKD---IKVLEKKRAMF--ECEVSEPDIT 3087

Query: 1275 VNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLV 1334
            V ++ +++E+    + K  I +   +  + +   +  D G YT  +  G  +     V  
Sbjct: 3088 VQWMKDDQELQITDRIK--IQKEKYVHRLLIPSTRMSDAGKYTV-VAGGNVSTAKLFVEG 3144

Query: 1335 GDV-FKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYK 1393
             DV  + ++KE +      I KQ                  +++ +V     + H  WYK
Sbjct: 3145 RDVRIRSIKKEVQV-----IEKQ----------------RAVVEFEVNEDDVDAH--WYK 3181

Query: 1394 DEREIS--VDEKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFK 1449
            D  EI+  V E+H +  +  I  + I+E  + DAG Y  +     G+++S + L   A +
Sbjct: 3182 DGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYVNAPE 3237

Query: 1450 --ELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKT 1507
              +++ E+      S    +  +   G              K++W      +    + K 
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRP----------QPKISWYKEEQLLSTGFKCKF 3287

Query: 1508 GVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIA 1567
               G++  L + E  P D   Y  E  +       +  LS +   E  +  Q +     A
Sbjct: 3288 LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV-PEVVSPDQEMPVYPPA 3346

Query: 1568 EKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNL-KFEAG 1626
                  ++  L D VT  EG+     C V G    +VSW   +K +       + +FE  
Sbjct: 3347 ------IITPLQDTVT-SEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED- 3397

Query: 1627 RTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPE 1667
             T    I      D G Y  V  N  G  +S   +S+  PE
Sbjct: 3398 -TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPE 3437



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 49/257 (19%), Positives = 89/257 (34%), Gaps = 50/257 (19%)

Query: 233  EETSEKKSRKVVIREKAERLSLRKT-LEETETYHAKLNEDH----------LLHAPEFII 281
            +E S     ++V  E++  L +    LE+T  Y  K++             +   P F++
Sbjct: 5275 KEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLV 5334

Query: 282  KPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEING 341
            KP          V+    + G P  ++ W+K+ V +    +  K  I        L +  
Sbjct: 5335 KPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVEL---VSGPKCFIGLEGSTSFLNLYS 5391

Query: 342  CDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYAS 401
             D   T QY     N  G  S    ++V                          P  +  
Sbjct: 5392 VDASKTGQYTCHVTNDVGSDSCTTMLLV------------------------TEPPKFVK 5427

Query: 402  RFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS 461
            + E            + G++  L C++  +PEI+     + W+RN   L  S   +  + 
Sbjct: 5428 KLEAS-------KIVKAGDSSRLECKIAGSPEIR-----VVWFRNEHELPASDKYRMTFI 5475

Query: 462  GERATLTFSHLNKEDEG 478
               A +  ++L+ ED G
Sbjct: 5476 DSVAVIQMNNLSTEDSG 5492



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 40/166 (24%), Positives = 64/166 (38%), Gaps = 21/166 (12%)

Query: 1492  WSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAY 1551
             W  +GS IR S + +    G+   L I +   +D G+Y   L  G      T  L     
Sbjct: 11151 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKL----- 11205

Query: 1552  DEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEK 1611
                           + E+   R +  L + VT+ +G+ L L+C +  +   +V W K+ K
Sbjct: 11206 --------------VVEELPVRFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGK 11249

Query: 1612  ALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETS 1657
              +       +    G     TIN     D+G Y + V+N    E S
Sbjct: 11250 IVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECS 11295



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 61/309 (19%), Positives = 119/309 (38%), Gaps = 50/309 (16%)

Query: 1143  EVVVNVDDDGVISLN---FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKD 1199
             E V +++D  V   +   F C     K+   W ++    ++  + + E  G+  ++  KD
Sbjct: 12824 EFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 12883

Query: 1200  LGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVK-SELAVEILEKG 1258
               +DD   Y+C V D    A  ++ +                  +PV+      +ILE  
Sbjct: 12884 CRLDDECEYACGVEDRKSRARLFVEE------------------IPVEIIRPPQDILEAP 12925

Query: 1259  QVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTF 1318
                    AE      +V ++ N   + +G K++M  +    I  + +  ++  D+G Y F
Sbjct: 12926 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGK--IHRLQICDIKPRDQGEYRF 12983

Query: 1319  QLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKC 1378
               +D +A     +     +     K A+   Q+ +   G      + ++           
Sbjct: 12984 IAKDKEARAKLELAAAPKI-----KTAD---QDLVVDVGKPLTMVVPYD----------- 13024

Query: 1379  KVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDK 1438
               A  K E    W+K+   +S  +  D      +  I E  K D G Y+++L++  GK +
Sbjct: 13025 --AYPKAEAE--WFKENEPLST-KTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAE 13079

Query: 1439  S--RLKLVD 1445
                 LK++D
Sbjct: 13080 GFINLKVID 13088



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 52/250 (20%), Positives = 85/250 (34%), Gaps = 51/250 (20%)

Query: 252  LSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWY 311
            +S   TL  TE Y            P F+ +P+S T +  +  K  C++ G P     W 
Sbjct: 3537 VSCTATLTVTEAY-----------PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQ 3585

Query: 312  KNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKR 371
            K+   ++   N   + I      H LE++    +D   Y   A N  G     A +++  
Sbjct: 3586 KDGAALSPSPN---WRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII-- 3640

Query: 372  YKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVIT 431
                 D+  F            + P   A   ++H + + D              +V +T
Sbjct: 3641 ----IDKPHFIK---------ELEPVQSAINKKVHLECQVDED-----------RKVTVT 3676

Query: 432  PEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYE 491
                       W ++G  L P K  +  +  + ATL       +D G Y           
Sbjct: 3677 -----------WSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSS 3725

Query: 492  QYSAYVFVRD 501
              SA V VR+
Sbjct: 3726 SCSATVTVRE 3735



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 51/252 (20%), Positives = 86/252 (34%), Gaps = 46/252 (18%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P F+ KP S  V     V L  +  G     + W+K    +    + G   I       +
Sbjct: 4206 PSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKEL---VSGGSCYITKEALESS 4262

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTP 396
            LE+      D+  Y     NV G +   A++ VK                         P
Sbjct: 4263 LELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE------------------------P 4298

Query: 397  YGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWV 456
              +  + E            ++G+   L C+V  TP IK     I W+ N   +  S   
Sbjct: 4299 ATFVEKLE-------PSQLLKKGDATQLACKVTGTPPIK-----ITWFANDREIKESSKH 4346

Query: 457  QTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDV 516
            +  +    A L  + +  ED G Y    +     +  S+ V V++       +P    + 
Sbjct: 4347 RMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKE-------SPYFTKEF 4399

Query: 517  KCLEANKDYIII 528
            K +E  K+Y ++
Sbjct: 4400 KPIEVLKEYDVM 4411



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST- 1638
             D V ++ G+A  L  +V G PPP + W K+ K L       +K     T    +N  ST 
Sbjct: 21469 DTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN--LVNKDSTR 21526

Query: 1639  ADSGKYGLVVKNKYGSETSDFTVSV 1663
              DSG Y L   N  G     F V V
Sbjct: 21527 RDSGAYTLTATNPGGFAKHIFNVKV 21551



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 36/155 (23%), Positives = 63/155 (40%), Gaps = 16/155 (10%)

Query: 1510  TGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEK 1569
             +G+  W + N+    DK   +  L +         +   + + E      R ++ A++ K
Sbjct: 30472 SGDSAWKKSNKERIKDKQFTIGGLLEA-------TEYEFRVFAENETGLSRPRRTAMSIK 30524

Query: 1570  NRARVLGGLPDV------VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKF 1623
              +    G  P +      VT + G+A  L+C + G P P++ W +  K L       +  
Sbjct: 30525 TKL-TSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSS 30583

Query: 1624  EAGRTAYFTINGVSTADSGKYGLVVKNKYGS-ETS 1657
             + GRT   T+      D G Y  +  N+ G  ETS
Sbjct: 30584 D-GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 30617



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 112/546 (20%), Positives = 188/546 (34%), Gaps = 108/546 (19%)

Query: 1110 SYVFRVRAINQAGVGKPSDLAGPVVAETRP-----GTKEVVVNVDDDGVISLNFECDKMT 1164
            +Y F + A+  +  G+ S  +  V+   +      GTK V+             EC    
Sbjct: 2424 NYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVL-------------ECKVSV 2470

Query: 1165 PK-SEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            P  +   W  +    +   R++   KG K ++        D G Y   V     + ++  
Sbjct: 2471 PDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIV---GRVETNCN 2527

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
            +  E++K +  L       T  V  E  VE+   G    W               F +KE
Sbjct: 2528 LSVEKIKIIRGLRDLTCTETQNVVFE--VELSHSGIDVLWN--------------FKDKE 2571

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQK 1343
            I    KYK  I+ +  I ++ +  +  +DEG YTF   +   +   TV   G + K L  
Sbjct: 2572 IKPSSKYK--IEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVA-GGAISKPLTD 2628

Query: 1344 EAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEK 1403
            +   + QE                       + +C+VAN   ++   W +D + + +   
Sbjct: 2629 QTVAESQE----------------------AVFECEVAN--PDSKGEWLRDGKHLPLTNN 2664

Query: 1404 -HDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALS 1462
                 DG    LI   +K D  I E   K    K  ++LK+  EA          KI  +
Sbjct: 2665 IRSESDGHKRRLIIAATKLD-DIGEYTYKVATSKTSAKLKV--EAV---------KIKKT 2712

Query: 1463 ATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPT 1522
              +L +  T + +         V+   V W  NG  +  +++    V G    L+I    
Sbjct: 2713 LKNLTVTETQDAVFTVELTHPNVKG--VQWIKNGVVLESNEKYAISVKGTIYSLRIKNCA 2770

Query: 1523 PNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVV 1582
              D+  Y   L  G+ G    +                ++   I +K         P  V
Sbjct: 2771 IVDESVYGFRL--GRLGASARL---------------HVETVKIIKK---------PKDV 2804

Query: 1583 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
            T  E   +    +V  D  P V W      +   D   L  E  +     +  +S +D+G
Sbjct: 2805 TALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSER-KVHKLMLQNISPSDAG 2862

Query: 1643 KYGLVV 1648
            +Y  VV
Sbjct: 2863 EYTAVV 2868



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P F  KP      +  +V L C + G P   V+WYK++  +    +  KY I S   + +
Sbjct: 7399 PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELR---SGKKYKIMSENFLTS 7455

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            + I   D  D  +Y+  A N  G  +   S+ +K
Sbjct: 7456 IHILNVDAADIGEYQCKATNDVGSDTCVGSIALK 7489



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 41/193 (21%), Positives = 67/193 (34%), Gaps = 36/193 (18%)

Query: 292  ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
            E+    C + G    +V+W K+   I    + GKY I        L +   D  D+ QY 
Sbjct: 8168 ESADFECHVTGTQPIKVSWAKDSREIR---SGGKYQISYLENSAHLTVLKVDKGDSGQYT 8224

Query: 352  ASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKF 411
              A+N  G+ S  A + +K                       + P  +  R     ++  
Sbjct: 8225 CYAVNEVGKDSCTAQLNIKE---------------------RLIPPSFTKRLSETVEE-- 8261

Query: 412  DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH 471
                  EG +  L  RV  +  I      + WY+N + + P+   +  +      L    
Sbjct: 8262 -----TEGNSFKLEGRVAGSQPI-----TVAWYKNNIEIQPTSNCEITFKNNTLVLQVRK 8311

Query: 472  LNKEDEGLYTIRV 484
                D GLYT +V
Sbjct: 8312 AGMNDAGLYTCKV 8324



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  VVTI+    L L   + G P PEV W ++     S D  +++  +  T    +  V+
Sbjct: 21866 LRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGE--SLDKASIESTSSYTLLI-VGNVN 21922

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSGKY L V+N  GS+++   V V
Sbjct: 21923 RFDSGKYILTVENSSGSKSAFVNVRV 21948



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  ++ I+ G +L L   + G P PEV W K +  +   D   +   +  T+   ++ V+
Sbjct: 22948 LRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIR--DAAIIDVTSSFTS-LVLDNVN 23004

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSGKY L ++N  G++++  TV V
Sbjct: 23005 RYDSGKYTLTLENSSGTKSAFVTVRV 23030



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 7/82 (8%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEK--ALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             ++ G ++ L     G P P   W K +   +L +D H    F        T+   +  D+
Sbjct: 28369 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST-----LTVENCNRNDA 28423

Query: 1642  GKYGLVVKNKYGSETSDFTVSV 1663
             GKY L V+N  GS++  FTV V
Sbjct: 28424 GKYTLTVENNSGSKSITFTVKV 28445



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 6/78 (7%)

Query: 1356  QGPHFVEYL-SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVD----EKHDFKDGI 1410
             Q PHF E L +  V  + N  L CKV    K   + WY+  +EI  D       +FK G 
Sbjct: 30926 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI-VKWYRQGKEIIADGLKYRIQEFKGGY 30984

Query: 1411  CTLLITEFSKKDAGIYEV 1428
               L+I   +  DA +Y+V
Sbjct: 30985 HQLIIASVTDDDATVYQV 31002



 Score = 39.7 bits (91), Expect = 0.025
 Identities = 34/135 (25%), Positives = 52/135 (38%), Gaps = 9/135 (6%)

Query: 245   IREKAERLSL-----RKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENV-KLHC 298
             I EK  ++S      +KT E T T   +      + +   I+     T    ++V K   
Sbjct: 32814 IHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAV 32873

Query: 299   SIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVK 358
                G P P   W K+   I      GKY +    G   LEI+  D  D+  Y  +  N  
Sbjct: 32874 KATGEPRPTAIWTKDGKAIT---QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSA 32930

Query: 359   GELSAYASVVVKRYK 373
             G +S+   + +K  K
Sbjct: 32931 GSVSSSCKLTIKAIK 32945



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 36/157 (22%), Positives = 63/157 (40%), Gaps = 10/157 (6%)

Query: 1511  GEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKN 1570
             G   W+   EP    K + V  L +GK    +   L+ Q   +     + ++     E  
Sbjct: 13630 GSDKWVACGEPVAETKME-VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAP 13688

Query: 1571  R----ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG 1626
                   ++L GL    T++ G  + L   V G P P+++W K +  L  D    ++    
Sbjct: 13689 EIFLDVKLLAGL----TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVP 13743

Query: 1627  RTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
             + +  TI     +D+G Y +   N  G  T+   V+V
Sbjct: 13744 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 13780



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 11/191 (5%)

Query: 180   TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
             TS Q + S Q   S Q +ASKQ  +    ++S  S+ +     S  A S    +E+  + 
Sbjct: 33242 TSLQGSFSSQ---SVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEM 33298

Query: 240   SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
             S    +      +S    LE + +   K     +   P+    P   ++ E + + + C+
Sbjct: 33299 SSSSFMG-----ISNMTQLESSTSKMLKAGIRGI--PPKIEALPSDISIDEGKVLTVACA 33351

Query: 300   IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
               G P P VTW      I+     G++ IE+   + TL I     +D   Y  S  N  G
Sbjct: 33352 FTGEPTPEVTWSCGGRKIH-SQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 33410

Query: 360   ELSAYASVVVK 370
               SA  ++ ++
Sbjct: 33411 SDSATVNIHIR 33421



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 54/228 (23%), Positives = 97/228 (42%), Gaps = 27/228 (11%)

Query: 144  RQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQT-----TASKQSTA 198
            R KH  G T      ++EA   +    L+ S++ +    Q TA  Q      TA     +
Sbjct: 1159 RNKH--GETSASASLLEEADYEL----LMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYS 1212

Query: 199  SKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRKTL 258
              +    K+    R+  A    VV     + ++ +E       + +I+E   R+ ++ TL
Sbjct: 1213 EYEKEYEKEQALIRKKMAKDTVVVR----TYVEDQEFHISSFEERLIKEIEYRI-IKTTL 1267

Query: 259  EET------ETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYK 312
            EE       E     ++E   + +  F  + +++ + E   V  HC ++G+P P++ WYK
Sbjct: 1268 EELLEEDGEEKMAVDISESEAVESG-FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYK 1326

Query: 313  NQVPINVHANPGKYIIE-SRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
            +   I    +  +Y ++  + G  +L I     ED   Y A A N+KG
Sbjct: 1327 DGKRIK---HGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1371



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 63/315 (20%), Positives = 110/315 (34%), Gaps = 43/315 (13%)

Query: 171  LLASEEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSA- 229
            +L  +EGI T+  S        S +      +     +        SR   +S ++ S  
Sbjct: 1354 VLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRS 1413

Query: 230  -LQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTV 288
             ++        +R    R    R+S  + LEET+      ++   L+ P F++KP S   
Sbjct: 1414 PIRMSPARMSPARMSPARMSPARMSPGRRLEETDE-----SQLERLYKPVFVLKPVSFKC 1468

Query: 289  WEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTA 348
             E +  +    + G P P   W+ +   I V+    K +I+   G  +L I      D+ 
Sbjct: 1469 LEGQTARFDLKVVGRPMPETFWFHDGQQI-VNDYTHKVVIKED-GTQSLIIVPATPSDSG 1526

Query: 349  QYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFD 408
            ++   A N  G  S    + V+  + +                  V P          F 
Sbjct: 1527 EWTVVAQNRAGRSSISVILTVEAVEHQ------------------VKPM---------FV 1559

Query: 409  DKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGER--AT 466
            +K      +EG  + +  R    P      P+I W +N   + P K+ +    G +  A 
Sbjct: 1560 EKLKNVNIKEGSRLEMKVRATGNP-----NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAA 1614

Query: 467  LTFSHLNKEDEGLYT 481
            L       +D   YT
Sbjct: 1615 LKIDSTVSQDSAWYT 1629



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 3/94 (3%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P F  KP      +  +V L C I+G P   V W K++  +    N  K+ I S++   +
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVR---NSKKFKITSKHFDTS 6514

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            L I   +  D  +Y   A N  G  +   SV  K
Sbjct: 6515 LHILNLEASDVGEYHCKATNEVGSDTCSCSVKFK 6548



 Score = 38.5 bits (88), Expect = 0.056
 Identities = 51/214 (23%), Positives = 73/214 (34%), Gaps = 41/214 (19%)

Query: 272  HLL-HAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIES 330
            HLL   P F+ K         + V L  ++ G     VTW K Q  I      GK  +  
Sbjct: 3918 HLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIR---EDGKIKMSF 3974

Query: 331  RYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
              G+  L I         +Y   A N  G  ++   ++VK                    
Sbjct: 3975 SNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKE------------------- 4015

Query: 391  SFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPL 450
                 P     R E+       V+    G+  +L   V  TPE+K      +WY++G PL
Sbjct: 4016 -----PAKIIERAEL-----IQVT---AGDPATLEYTVAGTPELKP-----KWYKDGRPL 4057

Query: 451  SPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRV 484
              SK  +  +    A L F      D G YT  +
Sbjct: 4058 VASKKYRISFKNNVAQLKFYSAELHDSGQYTFEI 4091



 Score = 38.5 bits (88), Expect = 0.056
 Identities = 43/205 (20%), Positives = 75/205 (36%), Gaps = 39/205 (19%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P F +KP S  +   E+    C + G    ++TW K+   I    N    ++E+   +  
Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTV 7271

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTP 396
            L++      D  QY   A N+ G+ S  A + V+                         P
Sbjct: 7272 LKVGK---GDAGQYTCYASNIAGKDSCSAQLGVQE------------------------P 7304

Query: 397  YGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWV 456
              +  + E            ++ E     C++  +PEIK     + WY++   +  S   
Sbjct: 7305 PRFIKKLE-------PSRIVKQDEFTRYECKIGGSPEIK-----VLWYKDETEIQESSKF 7352

Query: 457  QTLWSGERATLTFSHLNKEDEGLYT 481
            +  +    A L   +L+ ED G YT
Sbjct: 7353 RMSFVDSVAVLEMHNLSVEDSGDYT 7377



 Score = 38.5 bits (88), Expect = 0.056
 Identities = 76/371 (20%), Positives = 137/371 (36%), Gaps = 83/371 (22%)

Query: 231   QQEETSEKKSRKVVIREKAERLSLRK--TLEETETYHAKLNEDH------LLHAPEFIIK 282
             + ++T E   +  VI +  +R+ + K  TL++  TY   +          ++     ++ 
Sbjct: 12586 RDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVP 12645

Query: 283   PRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGC 342
              +   V E++ V  +C +      +  W++N+  I    +  KYII  +  ++TL I   
Sbjct: 12646 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAI---FDSSKYIILQKDLVYTLRIRDA 12701

Query: 343   DFEDTAQYRASAMNVKGE-LSAYASVVVKR------------YKGEFDETRFHAGASTMP 389
               +D A Y  S  N +GE + + A+++V+                E     F    + + 
Sbjct: 12702 HLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLN 12761

Query: 390   LSFGVTPYGYASRFEIHFD-------DKF-------DVSFGREGETM-------SLGCRV 428
             ++   T  G     E+ FD       DK+       D  F  EGE +       S+   +
Sbjct: 12762 VTLKWTKNGE----EVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELL 12817

Query: 429   VI---TPEIKHFQPE--------------------IQWYRNGVPLSPSKWVQTLWSGERA 465
             +I   T  ++H + +                    ++WYRNG  +   K  +    G   
Sbjct: 12818 IIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIH 12877

Query: 466   TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLD------VKCL 519
              L       +DE  Y      G    +  A +FV +   EI   P   L+      V   
Sbjct: 12878 RLIIKDCRLDDECEYA----CGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLA 12933

Query: 520   EANKDYIIISW 530
             E NKD + + W
Sbjct: 12934 ELNKDKVEVQW 12944



 Score = 38.5 bits (88), Expect = 0.056
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 5/105 (4%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKAL--ASDDHCNLKFEAGRTAYFTINGVS 1637
             D + ++ G+ +++  +V G P P++ W KNE  +   +D     K E  R+   T   + 
Sbjct: 15406 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 15465

Query: 1638  TA---DSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLK 1679
              A   D G Y +   N+ GS   +  V V+      R  A+  +K
Sbjct: 15466 KAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIK 15510



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 27/122 (22%), Positives = 55/122 (45%), Gaps = 7/122 (5%)

Query: 1532 ELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALN 1591
            +L +G+ G Q+  +L   A++ A       ++    EK +  ++   P+ V + EG+   
Sbjct: 1805 QLPEGRKGLQRIEELERMAHEGALTGVTTDQK----EKQKPDIVL-YPEPVRVLEGETAR 1859

Query: 1592 LTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNK 1651
              C V G P P+V+W  N + +       ++++     Y  I    + D+G+  +  +N 
Sbjct: 1860 FRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG--IHYLDIVDCKSYDTGEVKVTAENP 1917

Query: 1652 YG 1653
             G
Sbjct: 1918 EG 1919



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 36/174 (20%), Positives = 69/174 (39%), Gaps = 20/174 (11%)

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             F C+    K    W K+      S  + + S+G   K+  K++ +DD+      V +   
Sbjct: 11593 FVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSS 11652

Query: 1218  IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
              A   +++ +             + TV +  + AV   EK ++    +  K   +  V +
Sbjct: 11653 TAQLKVLEAD------------PYFTVKLHDKTAV---EKDEITLKCEVSK---DVPVKW 11694

Query: 1278  IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTV 1331
               + +EI   PKY +  D    I++  ++K   +D+G Y       K   + TV
Sbjct: 11695 FKDGEEIVPSPKYSIKADGLRRILK--IKKADLKDKGEYVCDCGTDKTKANVTV 11746



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 3/78 (3%)

Query: 293  NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352
            ++ + C ++G       W+K+   I+  A   KY +       +LE+N  + EDTA Y  
Sbjct: 5253 SIHMECKVSGSLPISAQWFKDGKEISTSA---KYRLVCHERSVSLEVNNLELEDTANYTC 5309

Query: 353  SAMNVKGELSAYASVVVK 370
               NV G+ +    + VK
Sbjct: 5310 KVSNVAGDDACSGILTVK 5327



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 158/804 (19%), Positives = 285/804 (35%), Gaps = 152/804 (18%)

Query: 903   VQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDK--- 959
             +++   PPP++  P+   +   LK +    PP+PP +    + F+   +   K P+K   
Sbjct: 10855 IKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQV 10914

Query: 960   -----IGGAEITGYYVNYREVI-DGVPGKWREANVKAV-----SEEAYKISNLKENMVYQ 1008
                  +   ++ G     R+++ +  P    E  +K+V      EE  K+   K   V +
Sbjct: 10915 PEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKK 10974

Query: 1009  FQVAA----MNMAGLGAPSA------VSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQ 1058
               V        +  +  P+       + E  K  E   A+P P    K     +   +  
Sbjct: 10975 PAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKP 11034

Query: 1059  WKPPVHSGRTP----VTGYFVDLK-EAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVF 1113
               PPV    TP    VT   V  K EAKA +++     +  IK V  K     E      
Sbjct: 11035 --PPVEPEPTPIAAPVTVPVVGKKAEAKAPKEE-AAKPKGPIKGVPKKTPSPIEAERRKL 11091

Query: 1114  RVRAINQAGVGKPSDLAG------PVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKS 1167
             R  +    G  KP D A        V  +     K++++   +    S  FEC      +
Sbjct: 11092 RPGS----GGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTA 11147

Query: 1168  EFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEE 1227
               +W KD  +  +SP+    + G   K+   D+ + D G Y+C                 
Sbjct: 11148 ITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTC----------------- 11190

Query: 1228  ELKRLLALSHEHKFPTVP-VKSELAVEILEKGQVRFW-MQAEKLSGNAKVNYIFNEKEIF 1285
                 +L L ++ K  T   V  EL V  ++  +     ++ + L  + ++N    E+++ 
Sbjct: 11191 ----VLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELN---KERDVV 11243

Query: 1286  EGPKYKMHIDRNTGII--------EMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDV 1337
                  K+ +++   I+         + +    D D GTYT  +++      S+ V V +V
Sbjct: 11244 WRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEV 11303

Query: 1338  FKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDERE 1397
              +           +W+ K            V  +   +  C +A  K   +I W+K   E
Sbjct: 11304 IR-----------DWLVK------PIRDQHVKPKGTAIFACDIA--KDTPNIKWFKGYDE 11344

Query: 1398  ISV---DEKHDFKDG-ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1453
             I     D+    +DG    L I     +D   Y V ++  R                   
Sbjct: 11345 IPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKR------------------- 11385

Query: 1454  EVCKKIALSATDLKIQSTAEGIQLY-----SFVTYYVE-DLKVNWSHNGSAIRYSDRVKT 1507
                 K+ L   ++++    E + +Y     SF     E D+   W   G  +R S   + 
Sbjct: 11386 -YPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEI 11444

Query: 1508  GVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIA 1567
                G + +L +++   +  G+ + +  +  T    T  L+ +  +  +A    LK   + 
Sbjct: 11445 KAEGGKRFLTLHKVKLDQAGEVLYQALNAIT----TAILTVKEIELDFA--VPLKDVTVP 11498

Query: 1568  EKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGR 1627
             E+ +AR      + V  +E                 V W K    + S D  ++    G+
Sbjct: 11499 ERRQARF-----ECVLTREA---------------NVIWSKGPDIIKSSDKFDI-IADGK 11537

Query: 1628  TAYFTINGVSTADSGKYGLVVKNK 1651
                  IN     D G Y   V+ K
Sbjct: 11538 KHILVINDSQFDDEGVYTAEVEGK 11561



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 1/83 (1%)

Query: 1581  VVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTAD 1640
             +V  + G  + +   V G P P V+W K ++ L      N +  A  T    IN    +D
Sbjct: 21074 LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST-ILNINECVRSD 21132

Query: 1641  SGKYGLVVKNKYGSETSDFTVSV 1663
             SG Y L  +N  G      T+ V
Sbjct: 21133 SGPYPLTARNIVGEVGDVITIQV 21155



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 18/77 (23%), Positives = 36/77 (46%)

Query: 1587  GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
             G+ +++     G P P ++W K +  + ++ H  +      T+    NGV   D+G Y +
Sbjct: 31042 GEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVV 31101

Query: 1647  VVKNKYGSETSDFTVSV 1663
               KN++G +     + V
Sbjct: 31102 CAKNRFGIDQKTVELDV 31118



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 3/94 (3%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P F   P      +   V L C ++G P   V WYK++  +    +  KY I S+    +
Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLR---SSKKYKIASKNFHTS 5573

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            + I   D  D  +Y   A N  G  +   +V +K
Sbjct: 5574 IHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLK 5607



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 21/84 (25%), Positives = 33/84 (39%), Gaps = 3/84 (3%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G  + +   V G PPP V+W  NE+ L  +           ++   I     +
Sbjct: 16532 DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIE---TTAISSSMVIKNCQRS 16588

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
               G Y L+ KN+ G       V V
Sbjct: 16589 HQGVYSLLAKNEAGERKKTIIVDV 16612



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             +  ++T++ G  + L   V+G P P VSW K+   L   +   +  +        +  V+
Sbjct: 19301 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR-NLCTLELFSVN 19359

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG Y +  +N  GS+++   + V
Sbjct: 19360 RKDSGDYTITAENSSGSKSATIKLKV 19385



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 1583  TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
             ++Q G+ L +   + G P P ++W K+   L      N+      T   +I      D G
Sbjct: 23240 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT-LSIKETHKDDGG 23298

Query: 1643  KYGLVVKNKYGSETSDFTV 1661
             +YG+ V N  G +T+   +
Sbjct: 23299 QYGITVANVVGQKTASIEI 23317



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             + +  G+ + L   + G PPP  SW      L   +   ++    + A  TI   +  D+
Sbjct: 29748 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT-KVAKLTIRETTIRDT 29806

Query: 1642  GKYGLVVKNKYGSETSDFTVSVFI 1665
             G+Y L +KN  G  T+  T+ V I
Sbjct: 29807 GEYTLELKNVTG--TTSETIKVII 29828



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 8/93 (8%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLK-------NEKALASDDHCNLKFEAGRTAY 1630
             L + + ++EG  +N+   + G P P ++W K       N++ +  D H N K     T  
Sbjct: 16122 LKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KLVVDDTCT 16180

Query: 1631  FTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               I     +D+G Y +   N  G+ + +  ++V
Sbjct: 16181 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 16213



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 19/86 (22%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKN-----EKA----LASDDHCNLKFEAGRTAY 1630
             DV+ ++ G+ L +  ++ G P P +SW K+     E+A    +++D+H  L         
Sbjct: 25797 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLL--------- 25847

Query: 1631  FTINGVSTADSGKYGLVVKNKYGSET 1656
              T+      D+G+Y L +KN  G+ +
Sbjct: 25848 -TVKDCIRRDTGQYVLTLKNVAGTRS 25872



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 4/96 (4%)

Query: 279  FIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQ-VPINVHANPGKYIIESRYGMHTL 337
            F+ +P+S  V EK        + G P P V W K +   +N     G+  I  +     L
Sbjct: 8456 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLN---QGGRVFIHQKGDEAKL 8512

Query: 338  EINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYK 373
            EI      D+  YR  A N  GE+ +  ++ V   K
Sbjct: 8513 EIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERK 8548



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 293   NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352
             ++++   I G P P VTW K+ + +   AN     IE+      L I  C+  DT ++  
Sbjct: 20793 SIRIFVPIKGRPAPEVTWTKDNINLKNRAN-----IENTESFTLLIIPECNRYDTGKFVM 20847

Query: 353   SAMNVKGELSAYASVVV 369
             +  N  G+ S + +V V
Sbjct: 20848 TIENPAGKKSGFVNVRV 20864



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKAL-ASDDHCNLKFEAGRTAYFTINGVST 1638
             DV+ +  G+   L  ++ G P P+V W K+ K L  +     +K    +T     + + T
Sbjct: 24715 DVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRT 24774

Query: 1639  ADSGKYGLVVKNKYGSETSDFTVSV 1663
              D G+Y L + N  G+++   TV V
Sbjct: 24775 -DGGQYILKLSNVGGTKSIPITVKV 24798



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 277 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
           P F+ + +S TV +   V+L   + G P P V +Y++   I    +   + I     +++
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD---FQISQEGDLYS 160

Query: 337 LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
           L I     ED+  Y  +A N  G  ++ A ++V+
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 38/153 (24%), Positives = 61/153 (39%), Gaps = 11/153 (7%)

Query: 221   VVSKQATSALQQEETSEKKSRKVVIREKA-ERLSLRKTLEETETYHAKLNEDHLLHAPEF 279
             V   +  +  + E T  ++ +    R KA  R    K    TE   A   ++    APE 
Sbjct: 13635 VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQE----APEI 13690

Query: 280   IIKPR---SHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
              +  +     TV     ++L  ++ G PEP++TW K  +   +     +  IE+     T
Sbjct: 13691 FLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM---ILKQDKRITIENVPKKST 13747

Query: 337   LEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
             + I      DT  Y   A+NV G  +A   V V
Sbjct: 13748 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 13780



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             +VV  + G ++ L   + G P P + W K++K L ++    ++      A   I      
Sbjct: 26880 EVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRL 26938

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             +SG Y L ++N  GS ++   V +
Sbjct: 26939 NSGCYELKLRNAMGSASATIRVQI 26962



 Score = 35.4 bits (80), Expect = 0.47
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + I+ G++L +   V G P P V+W K+   +    +  +    G T+ F +   +  
Sbjct: 27966 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF-VRDATRD 28024

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
               G Y +  KN  GS  ++  V V
Sbjct: 28025 HRGVYTVEAKNASGSAKAEIKVKV 28048



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 2/64 (3%)

Query: 439 PEIQWYRNGVPLSPS--KWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAY 496
           PE+ W+R+G  +S S    VQ  +S  RA LT   + K + G Y+++   G      +A 
Sbjct: 35  PEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAE 94

Query: 497 VFVR 500
           + V+
Sbjct: 95  LLVK 98



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 51/247 (20%), Positives = 100/247 (40%), Gaps = 40/247 (16%)

Query: 14  DLSYRNKDVRST------VSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEAFRRASAS 67
           +L  R K+V +T      V+H Q  K+    +           SAA  +E E       +
Sbjct: 490 ELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVPKVVI-----SAAKAKEQETRISEEIT 544

Query: 68  SSQQQASQHALSSEVSRKAASAYDYGSSHGLTDSSLLLDDYSSKLSPKPKRAKHSLLSGE 127
             Q+Q +Q A+  E    AAS     ++             S+KL   P          +
Sbjct: 545 KKQKQVTQEAIRQETEITAASMVVVATAK------------STKLETVP--------GAQ 584

Query: 128 EKENLPSDYMVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLA-SEEGITTSKQSTA 186
           E+     D M       +K +     T   ++  A   + +++L++   EGITT ++   
Sbjct: 585 EETTTQQDQM---HLSYEKIMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKREQVQ 641

Query: 187 SKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIR 246
             Q    K++  +  ST +  +  +++    +++++  + T A +QE+  +    KV + 
Sbjct: 642 ITQEKMRKEAEKTALSTIAVATAKAKE----QETILRTRETMATRQEQI-QVTHGKVDVG 696

Query: 247 EKAERLS 253
           +KAE ++
Sbjct: 697 KKAEAVA 703



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 43/207 (20%), Positives = 77/207 (37%), Gaps = 20/207 (9%)

Query: 171  LLASEEGITTSKQS-----TASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQ 225
            LL+ +E  T ++++     T     T   + + +K+ TA         +  S+  +    
Sbjct: 4572 LLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTD 4631

Query: 226  ATSALQQEETSEKKSRKVV--IREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKP 283
              S L+   T +K S +    ++    R S +          A++N   L+  P F  K 
Sbjct: 4632 TVSILKIISTEKKDSGEYTFEVQNDVGRSSCK----------ARINVLDLIIPPSFTKKL 4681

Query: 284  RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
            +     +   + L C +AG     + W+K+   I+      KY          LEI+  +
Sbjct: 4682 KKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASE---KYKFSFHDNTAFLEISQLE 4738

Query: 344  FEDTAQYRASAMNVKGELSAYASVVVK 370
              D+  Y  SA N  G       + VK
Sbjct: 4739 GTDSGTYTCSATNKAGHNQCSGHLTVK 4765



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 1/75 (1%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             + ++ G  +     + G P P   W  +   + +D+H  ++ +   ++  TI      D+
Sbjct: 17520 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETD-NFSSVLTIKNCLRRDT 17578

Query: 1642  GKYGLVVKNKYGSET 1656
             G+Y + V N  GS+T
Sbjct: 17579 GEYQITVSNAAGSKT 17593



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             E++++   + G P PRVTW+K+ V I    N     I    G  +L +     +    Y 
Sbjct: 27974 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDVLGSTSLFVRDATRDHRGVYT 28030

Query: 352   ASAMNVKGELSAYASVVVKRYKGE 375
               A N  G   A   V V+   G+
Sbjct: 28031 VEAKNASGSAKAEIKVKVQDTPGK 28054



 Score = 34.7 bits (78), Expect = 0.80
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 295  KLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASA 354
            +L C IAG    RV+W+K+   I   A   +Y I    G  +LEI   D  D   +   A
Sbjct: 4131 RLDCKIAGSLPMRVSWFKDGKEI---AASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRA 4187

Query: 355  MNVKGELSAYASVVVK 370
             N  G   +  +++V+
Sbjct: 4188 TNSVGSKDSSGALIVQ 4203



 Score = 34.7 bits (78), Expect = 0.80
 Identities = 44/195 (22%), Positives = 66/195 (33%), Gaps = 37/195 (18%)

Query: 287  TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
            TV   E   L C +AG PE  V WYK+     +  +  K+       + +L I   + +D
Sbjct: 5714 TVTVGETCTLECKVAGTPELSVEWYKDG---KLLTSSQKHKFSFYNKISSLRILSVERQD 5770

Query: 347  TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
               Y     N  G+ S  A V V                     S    P  +  R +  
Sbjct: 5771 AGTYTFQVQNNVGKSSCTAVVDV---------------------SDRAVPPSFTRRLK-- 5807

Query: 407  FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                   + G  G +  L C+V  +  I      + W+     +      QT +S    T
Sbjct: 5808 ------NTGGVLGASCILECKVAGSSPI-----SVAWFHEKTKIVSGAKYQTTFSDNVCT 5856

Query: 467  LTFSHLNKEDEGLYT 481
            L  + L+  D G YT
Sbjct: 5857 LQLNSLDSSDMGNYT 5871



 Score = 34.7 bits (78), Expect = 0.80
 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L   + ++ G  + L   V G PPP+++W K    L      ++K       +     V+
Sbjct: 19699 LRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVN 19757

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               D+GKY L ++N  G +     V V
Sbjct: 19758 KYDAGKYILTLENSCGKKEYTIVVKV 19783



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 41/195 (21%), Positives = 77/195 (39%), Gaps = 19/195 (9%)

Query: 1389 IVWYKDEREISVDE----KHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLV 1444
            + W++D + IS       +  F DG   L I   +K ++G Y +   +  G+  S  +L+
Sbjct: 37   VSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELL 96

Query: 1445 ---DEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRY 1501
               + A    +  +        + +++Q    GI     V +Y          +G+ I+ 
Sbjct: 97   VKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPT-PVVKFY---------RDGAEIQS 146

Query: 1502 SDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR- 1560
            S   +    G+   L I E  P D G Y +   +       T +L  Q  +E  A+  + 
Sbjct: 147  SLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKT 206

Query: 1561 -LKQAAIAEKNRARV 1574
             +  A I+E  + R+
Sbjct: 207  IVSTAQISESRQTRI 221



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 7/94 (7%)

Query: 1577  GLPDVVTIQEGKALNLTCNVWGDPPPEVSWL---KNEKALASDDHC---NLKFE-AGRTA 1629
             G  D +  + G  + +   + G P P+ SW    K +KA+    H    + + E A  ++
Sbjct: 15815 GAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSS 15874

Query: 1630  YFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
                I     + +GKY +  KNK G +T++  V V
Sbjct: 15875 VIIIPECKRSHTGKYSITAKNKAGQKTANCRVKV 15908



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 5/83 (6%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG-RTAYFTINGVSTAD 1640
             + ++ G +  +     G P PE++W + E          ++ E G      +I+     D
Sbjct: 24034 IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSIDNCDRND 24089

Query: 1641  SGKYGLVVKNKYGSETSDFTVSV 1663
             +GKY L ++N  GS+++  TV V
Sbjct: 24090 AGKYILKLENSSGSKSAFVTVKV 24112



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 10/87 (11%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD----DHCNLKFEAGRTAYFTINGVS 1637
             + I  GK L +   V G P P   W K E  L  D    D+   K E        I    
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSE------LIIKDAL 15167

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSVF 1664
               D G+Y +   N  GS+ +   V VF
Sbjct: 15168 RKDHGRYVITATNSCGSKFAAARVEVF 15194



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 4/109 (3%)

Query: 1358 PHFVEYL-SWEVTGECNVLLKCKVANIKKETHIVWYKDEREI--SVDEKHDFKDGICTLL 1414
            P+FV+ L S  V     V L+ +V  I     + +Y+D  EI  S+D +   +  + +LL
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV-VKFYRDGAEIQSSLDFQISQEGDLYSLL 162

Query: 1415 ITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSA 1463
            I E   +D+G Y V   +  G+  S  +L+ +  +E+  +  K I  +A
Sbjct: 163  IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTA 211



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 5/67 (7%)

Query: 418  EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDE 477
            EG    L C+V + P++      ++WY N   + P   VQ +  G +  L  +  +  DE
Sbjct: 2458 EGTKAVLECKVSV-PDVT----SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDE 2512

Query: 478  GLYTIRV 484
            G Y + V
Sbjct: 2513 GPYKLIV 2519



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 3/94 (3%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P FI       +    N  L C ++G     ++W+K++  I    +  KY + S+  +  
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIR---SSKKYRLFSQKSLVC 3887

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            LEI   +  D  +Y     N  G+    A+ ++K
Sbjct: 3888 LEIFSFNSADVGEYECVVANEVGKCGCMATHLLK 3921



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
             I+ G  L L+  + G P P+V+W K ++   +    ++     +     I   +  D G 
Sbjct: 17230 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK---LEIRNAAHEDGGI 17286

Query: 1644  YGLVVKNKYGSETSDFTVSV 1663
             Y L V+N  GS+T    V V
Sbjct: 17287 YSLTVENPAGSKTVSVKVLV 17306



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 13/87 (14%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG--RTAYFT---INGV 1636
             + ++ G ++ +   + G P PEV+W K        D+ NLK  A    T  FT   I   
Sbjct: 20786 LVVRAGLSIRIFVPIKGRPAPEVTWTK--------DNINLKNRANIENTESFTLLIIPEC 20837

Query: 1637  STADSGKYGLVVKNKYGSETSDFTVSV 1663
             +  D+GK+ + ++N  G ++    V V
Sbjct: 20838 NRYDTGKFVMTIENPAGKKSGFVNVRV 20864



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 38/176 (21%), Positives = 75/176 (42%), Gaps = 16/176 (9%)

Query: 1165 PKSEFSWSKD--YVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSY 1222
            P  E SW +D   +ST   P +++     + K+T   +   + G YS   T+  G A+S 
Sbjct: 33   PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATS- 91

Query: 1223 LIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEK 1282
                 EL     L      P   V+   ++ + +  QVR  ++   +     V +  +  
Sbjct: 92   ---TAEL-----LVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIP-TPVVKFYRDGA 142

Query: 1283 EIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD--GKATNHSTVVLVGD 1336
            EI     ++  I +   +  + + +   ED GTY+    +  G+AT+ + +++ G+
Sbjct: 143  EIQSSLDFQ--ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 43/204 (21%), Positives = 67/204 (32%), Gaps = 47/204 (23%)

Query: 278  EFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTL 337
            + I KP+  T  E   V    S++    P V W+   V I       K+ + S   +H L
Sbjct: 2796 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPS---DKHRLVSERKVHKL 2851

Query: 338  EINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPY 397
             +      D  +Y A    V G+L   A + V+                           
Sbjct: 2852 MLQNISPSDAGEYTA----VVGQLECKAKLFVET-------------------------- 2881

Query: 398  GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQ 457
                   +H           E +T S  C      E+ HF     W +NGV +  S+  +
Sbjct: 2882 -------LHITKTMKNIEVPETKTASFEC------EVSHFNVPSMWLKNGVEIEMSEKFK 2928

Query: 458  TLWSGERATLTFSHLNKEDEGLYT 481
             +  G+   L   + + ED   YT
Sbjct: 2929 IVVQGKLHQLIIMNTSTEDSAEYT 2952



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
             ++ G +  +T    G P P V W K +  L +  + +      RT+  TI   +  DSGK
Sbjct: 26198 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDT--TDSRTS-LTIENANRNDSGK 26254

Query: 1644  YGLVVKNKYGSETSDFTVSV 1663
             Y L ++N   + +    V V
Sbjct: 26255 YTLTIQNVLSAASLTLVVKV 26274



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 5/45 (11%)

Query: 418  EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG 462
            EGET    CRV   P     QP++ WY NG  +  SK  +  + G
Sbjct: 1854 EGETARFRCRVTGYP-----QPKVNWYLNGQLIRKSKRFRVRYDG 1893



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 20/74 (27%), Positives = 31/74 (41%), Gaps = 3/74 (4%)

Query: 296  LHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAM 355
            L  ++AG PE +  WYK+  P+       KY I  +  +  L+    +  D+ QY     
Sbjct: 4036 LEYTVAGTPELKPKWYKDGRPL---VASKKYRISFKNNVAQLKFYSAELHDSGQYTFEIS 4092

Query: 356  NVKGELSAYASVVV 369
            N  G  S   +  V
Sbjct: 4093 NEVGSSSCETTFTV 4106



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 17/89 (19%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALA-------SDDHCNLKFEAGRTAYFTIN 1634
             + +++G  + LT  + G P P   W K  + ++       S+ H  L           I 
Sbjct: 30146 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTEL----------VIK 30195

Query: 1635  GVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
                  DSG Y LV++NK G +     V V
Sbjct: 30196 EADRGDSGTYDLVLENKCGKKAVYIKVRV 30224



 Score = 31.6 bits (70), Expect = 6.8
 Identities = 44/203 (21%), Positives = 71/203 (34%), Gaps = 46/203 (22%)

Query: 278   EFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTL 337
             +F+      TV E E     C ++   +  V W+KN   ++        +I S    H L
Sbjct: 11575 KFMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRT---VLISSEGKTHKL 11630

Query: 338   EINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPY 397
             E+     +D +Q +A       ELS+ A + V                          PY
Sbjct: 11631 EMKEVTLDDISQIKAQVK----ELSSTAQLKVLE----------------------ADPY 11664

Query: 398   GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQ 457
                  F +   DK  V    E + ++L C V     +K       W+++G  + PS    
Sbjct: 11665 -----FTVKLHDKTAV----EKDEITLKCEVSKDVPVK-------WFKDGEEIVPSPKYS 11708

Query: 458   TLWSGERATLTFSHLNKEDEGLY 480
                 G R  L     + +D+G Y
Sbjct: 11709 IKADGLRRILKIKKADLKDKGEY 11731



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 8/88 (9%)

Query: 1598 GDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTIN-GVS-TADSGKYGLVVKNKYGSE 1655
            GDP   V WL + K L + +   +  E G   Y +++ GV+ + DSG       NKYG  
Sbjct: 1730 GDPTMVVEWLHDGKPLEAANRLRMINEFG---YCSLDYGVAYSRDSGIITCRATNKYG-- 1784

Query: 1656 TSDFTVSVFIPEEEARMAALESLKGGKK 1683
             +D T +  I ++E  +     L  G+K
Sbjct: 1785 -TDHTSATLIVKDEKSLVEESQLPEGRK 1811



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 6/60 (10%)

Query: 419   GETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEG 478
             GET +  C      E+ +    ++WY  G  L PS  V     G+  TLT   +  ED G
Sbjct: 12210 GETATFDC------ELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAG 12263



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 1598  GDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETS 1657
             G P P  +W   +K L + D   +K      A   I+    +D G Y L ++N+  + + 
Sbjct: 13420 GYPRPTATWCFGDKVLETGDRVKMK-TLSAYAELVISPSERSDKGIYTLKLENRVKTISG 13478

Query: 1658  DFTVSVFIPEEEARMAALESLKGGKKAK 1685
             +  V+V      AR +A + LK G   K
Sbjct: 13479 EIDVNVI-----ARPSAPKELKFGDITK 13501



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 7/91 (7%)

Query: 1592  LTCNVWGDPPPEVSWLKNEKALASDDHCNLKFE----AGRTAYFTINGVSTADSGKYGLV 1647
             L C V G P P V W +  K + +D    LK+      G      I  V+  D+  Y + 
Sbjct: 30947 LVCKVTGHPKPIVKWYRQGKEIIAD---GLKYRIQEFKGGYHQLIIASVTDDDATVYQVR 31003

Query: 1648  VKNKYGSETSDFTVSVFIPEEEARMAALESL 1678
               N+ GS +   ++ V +P +      LE +
Sbjct: 31004 ATNQGGSVSGTASLEVEVPAKIHLPKTLEGM 31034


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score =  257 bits (656), Expect = 8e-68
 Identities = 233/902 (25%), Positives = 381/902 (42%), Gaps = 102/902 (11%)

Query: 405   IHFDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGE 463
             +  D KF DV   + GE + +   +   P      P I W ++G+ +      + + +  
Sbjct: 19484 VMMDVKFRDVIVVKAGEVLKINADIAGRP-----LPVISWAKDGIEIEERARTEIISTDN 19538

Query: 464   RATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANK 523
                LT     + D G Y + ++        +    V D      G PA PL++  L A K
Sbjct: 19539 HTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKP----GPPAGPLEINGLTAEK 19594

Query: 524   DYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFR 583
                 +SW +P  DGG+ I  Y ++K E    +W+ C +  ++     VT L++G  YIFR
Sbjct: 19595 --CSLSWGRPQEDGGADIDYYIVEKRETSHLAWTIC-EGELQMTSCKVTKLLKGNEYIFR 19651

Query: 584   VRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTD 643
             V  VNK G+G P   S  + ALDP                             VP PPT 
Sbjct: 19652 VTGVNKYGVGEPLE-SVAIKALDPFT---------------------------VPSPPTS 19683

Query: 644   LSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDL 702
             L +T  T+  + L W +P    G E   Y +E+ E  +  W RVN + PV   R     L
Sbjct: 19684 LEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKK-PVYDLRVKSTGL 19742

Query: 703   AEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES 762
              EG  Y +RV   N+AG+  PSE + +    D + +P  P K     +  T++ ++W + 
Sbjct: 19743 REGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKP 19802

Query: 763   --KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLS 820
                    + GY +E   +    W+    + ++G+ +T  GL TG  Y+FRV++VN  G S
Sbjct: 19803 LFDGGAPITGYTVEYKKSDDTDWKTSIQS-LRGTEYTISGLTTGAEYVFRVKSVNKVGAS 19861

Query: 821   EYSQDSE---AIEVKAAIGGGVSPDVCPALSDEPGG----LTASRGR----VHEASPPT- 868
             + S  S+   A E +      +  ++   L  + G         RGR    V  + P T 
Sbjct: 19862 DPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTD 19921

Query: 869   FQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKK 928
              +  A + +  ++ SL  + +N  + +  K + T+Q  L+           +    + K 
Sbjct: 19922 LRTRAYVDTTDSRTSL--TIENANRNDSGKYTLTIQNVLS----------AASLTLVVKV 19969

Query: 929   TDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
              D   P PP +IT  +  ++S VL W  P+  GGA +  Y++  RE       K   +  
Sbjct: 19970 LD--TPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKRE----ASKKAWVSVT 20023

Query: 989   KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCS 1048
                +  +YK++NL+E  +Y F+V+  N  G+G P+   E  K  E     P PP  L  +
Sbjct: 20024 NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITE----KPSPPEKLGVT 20079

Query: 1049  EVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEG 1108
              + KDS+ L W  P H G + +  Y V+  E   K   W  +  A  K+ +  V GL+E 
Sbjct: 20080 SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK--NW--VKCAVAKSTHHVVSGLREN 20135

Query: 1109  VSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISL----NFECD--- 1161
               Y FRV A NQAG+  P +L  PV+ + +    E+ +       + +    N + D   
Sbjct: 20136 SEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPI 20195

Query: 1162  KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
                P  + + S+D V  + + R   E       +  K+    D G Y     ++ G   +
Sbjct: 20196 SGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKA 20255

Query: 1222  YLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNE 1281
             ++        ++ L      P  P    +  +I E+     W   +   G+   NYI  +
Sbjct: 20256 FI-------NIVVLDR----PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLK 20304

Query: 1282  KE 1283
             +E
Sbjct: 20305 RE 20306



 Score =  248 bits (632), Expect = 5e-65
 Identities = 214/828 (25%), Positives = 356/828 (42%), Gaps = 107/828 (12%)

Query: 429  VITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGE 488
            ++ P   + + E +W++   PLS +K + T  + E+ +       K D+G Y I ++   
Sbjct: 6714 MVVPYDAYPKAEAEWFKENEPLS-TKTIDT--TAEQTSFRILEAKKGDKGRYKIVLQ--N 6768

Query: 489  YYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDK 548
             + +   ++ ++  D      P    +++  E     + ++W++P  DGGS I+GY +++
Sbjct: 6769 KHGKAEGFINLKVIDV-----PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVER 6823

Query: 549  CEVGTDSWSQCNDTPVKFARFPVTGLIEGR-SYIFRVRAVNKMGIGFPSRVSEPVAALDP 607
             ++   +W    D   +   F VTGL +G   Y+FRV A N++G G P     PV     
Sbjct: 6824 RDIKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPV----- 6877

Query: 608  AEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHE 667
                                  E  S+  VPGPP ++++T+  R  V L+W+PP   G  
Sbjct: 6878 ----------------------EARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGA 6915

Query: 668  GIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEA 726
             I  Y +E  +  +  W    T +  +     + D+ EG+ Y FRVR  N  GVG+PS A
Sbjct: 6916 EITNYVIELRDKTSIRWDTAMT-VRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAA 6974

Query: 727  TEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-KD-AKELVGYYIEASVAGSGKWE 784
            T    V D ++ P  P  +  S  T +SV + WE   KD    ++GY IE    G   W 
Sbjct: 6975 TPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWI 7034

Query: 785  PCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVC 844
             CN   V    +   GL  G  Y++RV A N AG+S+ S+                    
Sbjct: 7035 RCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEIL------------------ 7076

Query: 845  PALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVS-----KV 899
                   G LTA    V      +  KD L    PN  ++   S    +   +     KV
Sbjct: 7077 -------GPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 7129

Query: 900  SET----------VQEELTPPPQKAAPQG------KSKSDPLKKKTD---RAPPSPPCDI 940
             ET             EL   P + + +G      +++   +  + D    A PS P ++
Sbjct: 7130 LETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKEL 7189

Query: 941  TCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISN 1000
               +  +DS+ L W+ PD  GG+ +TGY V  REV       W +  +  V++  + + +
Sbjct: 7190 KFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKT---WTKV-MDFVTDLEFTVPD 7245

Query: 1001 LKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWK 1060
            L +   Y F+V A N  G G P+ V E          VP PP ++K  +   +S+ L W 
Sbjct: 7246 LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMST-PATVPDPPENVKWRDRTANSIFLTWD 7304

Query: 1061 PPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQ 1120
            PP + G + + GY V+        D+W    E  +    ++V GL+EG  Y +RV+A+N+
Sbjct: 7305 PPKNDGGSRIKGYIVE--RCPRGSDKWVACGE-PVAETKMEVTGLEEGKWYAYRVKALNR 7361

Query: 1121 AGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISL----NFECDKMT---PKSEFSWSK 1173
             G  KPS     + A       E+ ++V     +++      E        P+ + +W+K
Sbjct: 7362 QGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTK 7421

Query: 1174 DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
              +  +   R+ +E+   K+ +T  D    D G Y  +  +  G A++
Sbjct: 7422 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATA 7469



 Score =  247 bits (631), Expect = 6e-65
 Identities = 233/877 (26%), Positives = 353/877 (40%), Gaps = 116/877 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P + W ++G  L P++ ++        TL    +N++D G YTI        +  +  + 
Sbjct: 13020 PTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLK 13079

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V D        P  P  VK  +   D  ++SW+ P  DGGS I  Y +DK E    +W+Q
Sbjct: 13080 VLDK-------PGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQ 13132

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              + T V      V  LIEG  Y FR+ A NK G+G P   +EP  A +P +         
Sbjct: 13133 VSAT-VPITSCSVEKLIEGHEYQFRICAENKYGVGDPV-FTEPAIAKNPYDP-------- 13182

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                                PG      ++  T+ ++ +SWKPP   G   I  Y +EK E
Sbjct: 13183 -------------------PGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRE 13223

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
                 NW +VN + P+         L EG  Y FRV   N AG G+PS+A++     D   
Sbjct: 13224 TQAVNWTKVNRK-PIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQY 13282

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCN-NNPVKGS 794
              P  P        T +SV +SW +        ++GY +E   A S  W  CN    ++ +
Sbjct: 13283 PPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13342

Query: 795   RFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAI---GGGVSPDVCPALSDEP 851
             RF   GL+    Y FRV AVN  G S+ S   +    K  +    G +  D+   L    
Sbjct: 13343 RFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRA 13402

Query: 852   GGLTASRGRVHEASPPTFQKDALLGSKPN-----KPSLPSSS---------QNLGQTEVS 897
             G        V    PP      +  SKPN     +  L   S         +N+ + +  
Sbjct: 13403 GVTMRLYVPVKGRPPP-----KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13457

Query: 898   KVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQP 957
             K   T++             GK +   + K  D   P PP ++T  E  +DS  + W+ P
Sbjct: 13458 KYILTLENSC----------GKKEYTIVVKVLD--TPGPPVNVTVKEISKDSAYVTWEPP 13505

Query: 958   DKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMA 1017
                GG+ I  Y V  R   D     W     +  S+ +++++NL+E   Y F+V A N  
Sbjct: 13506 IIDGGSPIINYVVQKR---DAERKSWSTVTTEC-SKTSFRVANLEEGKSYFFRVFAENEY 13561

Query: 1018  GLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDL 1077
             G+G P    +  K  +     PGP   LK   V K S  + WK P   G + + GY VD 
Sbjct: 13562 GIGDPGETRDAVKASQ----TPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 13617

Query: 1078  KEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET 1137
                  +E++W+ + ++   ++    + L EG  Y FRV A N+ G G PS++   VVA  
Sbjct: 13618 ---LTEENKWQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVAR- 13669

Query: 1138  RPGTKEVVVNVDDDGVISL--------NFECD---KMTPKSEFSWSKDYVSTEDSPRLEV 1186
                   V  ++D  G+  L        NF      K  P    SW K         R+ V
Sbjct: 13670 ---DDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13726

Query: 1187  ESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPV 1246
             ES    T +   D    D G Y+  + +  G     +         + +  +   PT P+
Sbjct: 13727 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTI--------SIKVVGKPGIPTGPI 13778

Query: 1247  KSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
             K +   E+  +     W   +   G+   NYI  +++
Sbjct: 13779 KFD---EVTAEAMTLKWAPPKDDGGSEITNYILEKRD 13812



 Score =  247 bits (630), Expect = 8e-65
 Identities = 216/807 (26%), Positives = 347/807 (42%), Gaps = 78/807 (9%)

Query: 438  QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
            +P+I W +  + L   K +      +++T+T     + D G Y I         + +A V
Sbjct: 7414 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAV--NVCGRATAVV 7471

Query: 498  FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
             V   D      P  P      +   +  +++W  P  DGGS I  Y +++    ++ W 
Sbjct: 7472 EVNVLDK-----PGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWH 7526

Query: 558  QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAA---LDPAEKARLK 614
            + + T VK   F  T LI  + YIFRV A N  G+G P + S P+ A    DP       
Sbjct: 7527 KLSST-VKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQAS-PITAKYQFDP------- 7577

Query: 615  SRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFV 673
                                   PGPPT L  ++ T+  V L+W  P   G   I  Y+V
Sbjct: 7578 -----------------------PGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWV 7614

Query: 674  EKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVG 733
            E+ +  T+ W R N ++PVK   + +  L   K Y FRV   N AG G+PS++TE  ++ 
Sbjct: 7615 ERLDPDTDKWVRCN-KMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIK 7673

Query: 734  DKLDIPKAPGKIIPSRNTDTSVVVSW--EESKDAKELVGYYIEASVAGSGKWEPCNNNPV 791
            D +D P  PGK        TSV ++W   E     ++  Y IE    G+ +W       V
Sbjct: 7674 DPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEG-V 7732

Query: 792  KGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEP 851
              ++    GL+ GQ Y FRVRAVN AG SE S+ S+ +  +  +     P     ++   
Sbjct: 7733 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN--- 7789

Query: 852  GGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETV---QEELT 908
              +T +   +    P       +      K  +         T V     TV    E   
Sbjct: 7790 --ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSL 7847

Query: 909  PPPQKAAPQGKSKS------DPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGG 962
               + AA     +S      D +  K     P PP  +  ++  +  + L W+ P   GG
Sbjct: 7848 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGG 7907

Query: 963  AEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
              I  Y +  +E +     +W +A   A  +  ++++++ E    QFQV A N AG+G P
Sbjct: 7908 RPIQRYVIEKKERLG---TRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHP 7964

Query: 1023 SAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKA 1082
            S  +E    E+ T + P PP  L  ++  +  + + WKPP  +G +P+ GY V++     
Sbjct: 7965 SEPTEILSIEDPT-SPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEM--CPV 8021

Query: 1083 KEDQWRGLNEAAIKNVYLKV-RGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA---ETR 1138
              ++W  +N   IK++  KV  G+     YV RVRA+N  GV +PS+++  VVA   + +
Sbjct: 8022 GTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCK 8081

Query: 1139 P----GTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTK 1194
            P     T +++V   +   I + F   +  P    SW KD    + S RL +++      
Sbjct: 8082 PTIDLETHDIIVIEGEKLSIPVPF---RAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8138

Query: 1195 MTFKDLGMDDLGIYSCDVTDTDGIASS 1221
            +        D GIY+  + +  G A++
Sbjct: 8139 LEVPKSVRADAGIYTITLENKLGSATA 8165



 Score =  244 bits (623), Expect = 5e-64
 Identities = 210/715 (29%), Positives = 320/715 (44%), Gaps = 77/715 (10%)

Query: 432   PEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHL---NKEDEGLYTIRVR--M 486
             P I   +P I W ++G PL  +  V      E AT T  H+   NK+D G YT+      
Sbjct: 18029 PVIGRPRPNISWVKDGEPLKQTTRVNV---EETATSTVLHIKEGNKDDFGKYTVTATNSA 18085

Query: 487   GEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFI 546
             G   E  S  V       E  G P  P  V+  E + D+++ISW+ PA  GG  I  Y +
Sbjct: 18086 GTATENLSVIVL------EKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYIV 18137

Query: 547   DKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALD 606
             +K +  T +W   + T  +     +T L  G  Y FR+ A N+ G               
Sbjct: 18138 EKRDTTTTTWHMVSATVAR-TTIKITKLKTGTEYQFRIFAENRYG--------------- 18181

Query: 607   PAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGH 666
                        SAP   + ++ +    E   PGPP    VT  ++  +++ W  P   G 
Sbjct: 18182 ----------KSAPLDSKAVIVQYPFKE---PGPPGTPFVTSISKDQMLVQWHEPVNDGG 18228

Query: 667   EGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSE 725
               I+ Y +E+ E  +  W ++N + P++  +F    L EG  Y F+V   N  G+G+PS+
Sbjct: 18229 TKIIGYHLEQKEKNSILWVKLN-KTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 18287

Query: 726   ATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKW 783
              +E  V  D  D P  P  I+ +RN   +V + W++       ++ GY +E      G+W
Sbjct: 18288 VSECFVARDPCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW 18344

Query: 784   EPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAI---GGGV 839
                +   V  + FT  GLV  Q Y FRV A NAAG  SE S  S AI  +  I      +
Sbjct: 18345 MKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASL 18404

Query: 840   SP---DVCPALSDEPGGLTAS-RGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTE 895
              P   DV    + E   L A  RG+        + KD   G +  + +     ++  Q  
Sbjct: 18405 DPKYKDVIVVHAGETFVLEADIRGK--PIPDVVWSKD---GKELEETAARMEIKSTIQKT 18459

Query: 896   VSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKT-DR-APPSPPCDITCLESFRDSMVLG 953
                V + ++ +      K +  G +KS P+  K  DR  PP  P  +T + +  +   L 
Sbjct: 18460 TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTA--EKCYLA 18517

Query: 954   WKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAA 1013
             W  P + GGA I+ Y +  RE        W + + + V    YK++ L     Y F+V A
Sbjct: 18518 WNPPLQDGGANISHYIIEKRET---SRLSWTQVSTE-VQALNYKVTKLLPGNEYIFRVMA 18573

Query: 1014  MNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGY 1073
             +N  G+G P        C  +    PGPP + + S + KDS+V+ W  PV  G T + GY
Sbjct: 18574 VNKYGIGEPLESGPVTACNPY--KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY 18631

Query: 1074  FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              ++ ++ +    +W   N+  + ++ L+V GL EG SY FRV A N AGVG+PS+
Sbjct: 18632 ILEKRDKEGV--RWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSE 18684



 Score =  240 bits (612), Expect = 1e-62
 Identities = 232/891 (26%), Positives = 374/891 (41%), Gaps = 101/891 (11%)

Query: 417   REGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             R G  + L   V   PE     P+I W +    L   + V   ++G+RAT      ++ D
Sbjct: 22755 RAGSDLVLDAAVGGKPE-----PKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSD 22809

Query: 477   EGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVD 536
              G YT+ V+     +  S  V V D+       P   L V  +   K    ++W  P  D
Sbjct: 22810 SGKYTLTVKNASGTKAVSVMVKVLDSPG-----PCGKLTVSRVTQEK--CTLAWSLPQED 22862

Query: 537   GGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPS 596
             GG+ I  Y +++ E    +W          + + VT LI+   YIFRVRAVNK G G P 
Sbjct: 22863 GGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYGPGVPV 22921

Query: 597   RVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVL 656
               SEP+ A +                              +P PP         + ++++
Sbjct: 22922 E-SEPIVARNSFT---------------------------IPSPPGIPEEVGTGKEHIII 22953

Query: 657   SW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCS 715
              W KP    G+E   Y V+K E  +  W RVN +  V   R  +  L EG  Y FRV   
Sbjct: 22954 QWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAV 23013

Query: 716   NSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYI 773
             N+AG  EPSEA+      +    P  P        T  S+ ++W +       ++VGY +
Sbjct: 23014 NAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVL 23073

Query: 774   EASVAGSGKWEPCNNN-PVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVK 832
             E     + +W   + N  ++ + FT   L  GQ Y FRV AVN  G+SEYS+    IE  
Sbjct: 23074 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 23133

Query: 833   AAI---GGGVSPDVCPALSDEPGGLTASRGRVHEASPP--TFQKDAL-LGSKPNKPSLPS 886
               I      ++ D+   ++   G        V    PP  T+ K  + L S+    ++  
Sbjct: 23134 ERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASR----AIID 23189

Query: 887   SSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESF 946
             ++++     V KV+     + T   +  +  GK  +  L K  D   P P   +   E  
Sbjct: 23190 TTESYSLLIVDKVNRYDAGKYTIEAENQS--GKKSATVLVKVYDTPGPCP--SVKVKEVS 23245

Query: 947   RDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMV 1006
             RDS+ + W+ P   GGA +  Y V  RE        ++    K  S+  Y+IS L E  +
Sbjct: 23246 RDSVTITWEIPTIDGGAPVNNYIVEKRE---AAMRAFKTVTTKC-SKTLYRISGLVEGTM 23301

Query: 1007  YQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSG 1066
             Y F+V   N+ G+G P   S+     E    VP  P  L+  +V K ++ L W+ P++ G
Sbjct: 23302 YYFRVLPENIYGIGEPCETSDAVLVSE----VPLVPAKLEVVDVTKSTVTLAWEKPLYDG 23357

Query: 1067  RTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLK--VRGLKEGVSYVFRVRAINQAGVG 1124
              + +TGY   L+  KA  ++W  +    +K   L+  V  L EG  Y+FR+RA N+ GV 
Sbjct: 23358 GSRLTGYV--LEACKAGTERW--MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVS 23413

Query: 1125  KPSDLAGPVVAE-----------TRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSK 1173
             +P +    V  +           T P   +  ++V     + L        P +  SW  
Sbjct: 23414 EPRETVTAVTVQDLRVLPTIDLSTMP---QKTIHVPAGRPVELVIPIAGRPPPAA-SWFF 23469

Query: 1174  DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLL 1233
                   +S R+ VE+     K+T ++  + D G Y+ ++ +  G  S       E  +++
Sbjct: 23470 AGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTS-------ETIKVI 23522

Query: 1234  ALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVN-YIFNEKE 1283
              L      PT P+K    ++ ++   +    +  +L G A ++ Y+  +++
Sbjct: 23523 ILDKPGP-PTGPIK----IDEIDATSITISWEPPELDGGAPLSGYVVEQRD 23568



 Score =  239 bits (609), Expect = 2e-62
 Identities = 243/973 (24%), Positives = 389/973 (39%), Gaps = 133/973 (13%)

Query: 339   INGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYG 398
             + G    DT +YR SA+N+ G+            K E      H                
Sbjct: 10473 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLH---------------- 10516

Query: 399   YASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQT 458
                   + F DK  +   R GE  +L  R    P+     P++ W+++   +        
Sbjct: 10517 ------LDFRDKLTI---RVGEAFALTGRYSGKPK-----PKVSWFKDEADVLEDDRTHI 10562

Query: 459   LWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKC 518
               +     L      + D G Y + V       +    V V D      G P  P+    
Sbjct: 10563 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRP----GPPVGPVSFD- 10617

Query: 519   LEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGR 578
              E  KDY++ISWK P  DGGS I  Y I+K EVG D W        K     V+ L+EG+
Sbjct: 10618 -EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAK-TTCKVSKLLEGK 10675

Query: 579   SYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVP 638
              YIFR+ A N  GI      S+P+ +     K R +                      VP
Sbjct: 10676 DYIFRIHAENLYGI------SDPLVSDSMKAKDRFR----------------------VP 10707

Query: 639   GPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFA 698
               P    VTE T+   +++W  P   G     Y +EK E  ++ W RV  +      +F 
Sbjct: 10708 DAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFR 10767

Query: 699   LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVS 758
             + DL EG  Y FRV   N  G+G+PS  ++     D +  P  P        T  SV ++
Sbjct: 10768 VPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLT 10827

Query: 759   WEESK--DAKELVGYYIEASVAGSGKWEPCNNNP--VKGSRFTCHGLVTGQSYIFRVRAV 814
             W+  +     +++GY +E    G  +W   N+ P     +++   GL  GQ+Y FRV AV
Sbjct: 10828 WQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAV 10887

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGR-VHEASPPTFQKDA 873
             NAAG S+ +   E + VK  +     P++          L A+  R  H     T +  A
Sbjct: 10888 NAAGESDPAHVPEPVLVKDRL---EPPELI---------LDANMAREQHIKVGDTLRLSA 10935

Query: 874   LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSD---------- 923
             ++   P  P +    ++      +++      ++TP   K   +  +  D          
Sbjct: 10936 IIKGVP-FPKVTWKKEDRDAPTKARI------DVTPVGSKLEIRNAAHEDGGIYSLTVEN 10988

Query: 924   PLKKKTDRA------PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVID 977
             P   KT          P PP D+   E  +DS  L WK+P   GG+ IT Y V  R+V  
Sbjct: 10989 PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDV-- 11046

Query: 978   GVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIA 1037
                 +W   +  +  ++++   +L E   Y F+VAA N  G G      +  K  +  + 
Sbjct: 11047 -ASAQWSPLSATS-KKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD-PLH 11103

Query: 1038  VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
              PGPP  L   +V K  + L W  P   G +P+TGY V+ +E   ++  W  +    + N
Sbjct: 11104 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQD--W--IKFKTVTN 11159

Query: 1098  VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR--PGTKEVVVNVDDDGVI- 1154
             +   V GL++G +Y FRV+A N  G+G P D   P+  + +  P + E+ V + +  V+ 
Sbjct: 11160 LECVVTGLQQGKTYRFRVKAENIVGLGLP-DTTIPIECQEKLVPPSVELDVKLIEGLVVK 11218

Query: 1155  ---SLNFEC-DKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSC 1210
                ++ F    +  P     W+ D    +      VE+    + +T K+    D G Y  
Sbjct: 11219 AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11278

Query: 1211  DVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLS 1270
              V++  G         + +   L +      PT P+     +++  +     W   +   
Sbjct: 11279 TVSNAAG--------SKTVAVHLTVLDVPGPPTGPIN---ILDVTPEHMTISWQPPKDDG 11327

Query: 1271  GNAKVNYIFNEKE 1283
             G+  +NYI  +++
Sbjct: 11328 GSPVINYIVEKQD 11340



 Score =  238 bits (606), Expect = 5e-62
 Identities = 256/1027 (24%), Positives = 414/1027 (40%), Gaps = 150/1027 (14%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             +N+K+   + G P+P VTW K      +     +   E+      L IN C   D+  Y 
Sbjct: 14776 DNIKVEIPVLGRPKPTVTWKKGD---QILKQTQRVNFETTATSTILNINECVRSDSGPYP 14832

Query: 352   ASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKF 411
              +A N+ GE+    ++ V    G            T P+ F      +            
Sbjct: 14833 LTARNIVGEVGDVITIQVHDIPGP----------PTGPIKFDEVSSDF------------ 14870

Query: 412   DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH 471
              V+F  +      G        I ++  E++          + WV+   +  R T   + 
Sbjct: 14871 -VTFSWDPPENDGGV------PISNYVVEMR------QTDSTTWVELATTVIRTTYKATR 14917

Query: 472   LNKEDEGLYTIRVRMGEYY---EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIII 528
             L    E  Y  RV+    Y      ++   V +   ++ G P  P   +     KD + I
Sbjct: 14918 LTTGLE--YQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTP---QVTAVTKDSMTI 14972

Query: 529   SWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVN 588
             SW +P  DGGSPILGY +++ E     W   +   V    F  +GL +G +Y FRV A N
Sbjct: 14973 SWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAEN 15032

Query: 589   KMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTE 648
               G   PS+ SEP+ ALDP +                            PG P  L++T 
Sbjct: 15033 MAGKSKPSKPSEPMLALDPIDP---------------------------PGKPVPLNITR 15065

Query: 649   ATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKS 707
              T   V L W KP    G +   Y VEK +     W + N    +++  F +  L E  +
Sbjct: 15066 HT---VTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILEN-EFTVSGLTEDAA 15121

Query: 708   YCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAK 766
             Y FRV   N+AG +  PSE ++     D ++ PK              V V ++++   K
Sbjct: 15122 YEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKI------------KVDVKFKDTVILK 15169

Query: 767   ELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDS 826
                 + +EA V  SG+  P       G        +  +   F    VN        +DS
Sbjct: 15170 AGEAFRLEADV--SGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNK---DSTRRDS 15224

Query: 827   EAIEVKAAIGGGVSPDVC-------PALSDEPGGLT--ASRGRVHEASPPTFQKDALLG- 876
              A  + A   GG +  +        P   + P  +T   S   V    PP     A +  
Sbjct: 15225 GAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDH 15284

Query: 877   --------SKPNKPSLPSSSQ--NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLK 926
                     S+    ++ S  Q   L  T++ K +E +   +     K       +S+P+ 
Sbjct: 15285 YIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV--NKYGVGEPLESEPVL 15342

Query: 927   KKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREA 986
                   PP PP +       +DSMV+ W  PD  GG+EI  Y V  R   D    +W + 
Sbjct: 15343 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERR---DKAGQRWIKC 15399

Query: 987   NVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK-CEEWTIAVPGPPHSL 1045
             N K +++  YK+S L E   Y+F++ A N AG+ APS  S  +K C+  T+  PGPP + 
Sbjct: 15400 NKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD--TVFKPGPPGNP 15457

Query: 1046  KCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRG 1104
             +  +  + S+ + W  P++ G + +TGY V++  A  +ED+W+ +   A +K     + G
Sbjct: 15458 RVLDTSRSSISIAWNKPIYDGGSEITGYMVEI--ALPEEDEWQIVTPPAGLKATSYTITG 15515

Query: 1105  LKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECD--- 1161
             L E   Y  R+ A+N  G+G+P+ + G   AE R    E+ ++ D   V+++   C    
Sbjct: 15516 LTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRL 15575

Query: 1162  ----KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
                 K  P  E  W++D+  + D  +  +ES  + T +   ++   D G Y   V ++ G
Sbjct: 15576 FVPIKGRPAPEVKWARDHGESLD--KASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG 15633

Query: 1218  IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV-N 1276
               S+++             +     T     +L V+ + K  V        L G +K+ N
Sbjct: 15634 SKSAFV-------------NVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15680

Query: 1277  YIFNEKE 1283
             YI  ++E
Sbjct: 15681 YIVEKRE 15687



 Score =  236 bits (602), Expect = 1e-61
 Identities = 213/769 (27%), Positives = 319/769 (41%), Gaps = 97/769 (12%)

Query: 398   GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPE-----------IQWYRN 446
             G   +F +   +   VS  RE E +      ++ P+I    PE           I+ +  
Sbjct: 12561 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI--LMPEQITIKAGKKLRIEAHVY 12618

Query: 447   GVPLSPSKWVQTLWSGERATLTFSHL----------------NKEDEGLYTIRVRMGEYY 490
             G P    KW +    GE   +T SHL                 ++D G Y++        
Sbjct: 12619 GKPHPTCKWKK----GEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGT 12674

Query: 491   EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCE 550
             +     V V DA     G P  P D+  ++A  D   +SW  P  DGGS I  Y ++KC+
Sbjct: 12675 DTQKIKVVVMDAP----GPPQPPFDISDIDA--DACSLSWHIPLEDGGSNITNYIVEKCD 12728

Query: 551   VGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEK 610
             V    W     +  K +   V  LI G+ YIFRVRA N+ GI  P    + VA       
Sbjct: 12729 VSRGDWVTALASVTKTS-CRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG-- 12785

Query: 611   ARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM 670
                                       VP  P +  VT+  +  + ++W  P   G   I+
Sbjct: 12786 --------------------------VPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPII 12819

Query: 671   -YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEV 729
              Y +E+ E  +  W + N  L V+S  +    L EG  Y FR+   N AG   PS+ TE 
Sbjct: 12820 GYLIERKERNSLLWVKANDTL-VRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEY 12878

Query: 730   TVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNN 789
                   +D P  P  I  +++T  S++ +  +     +++GY++EA      KW  CN  
Sbjct: 12879 VTARMPVDPPGKPEVIDVTKST-VSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTA 12937

Query: 790   P--VKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSP--DVCP 845
             P  +    +T  GL     Y FR  A  A  +S  S+ S+ + + A     V P  D+  
Sbjct: 12938 PHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAE---NVPPRIDLSV 12994

Query: 846   ALSD----EPGGLTASRGRVHEASPPT--FQKDALLGSKPNKPSLPSSSQNLGQTEVSKV 899
             A+      + G        V     PT  ++KD  L  KP +    +  +NL   E+  V
Sbjct: 12995 AMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL-LKPAEGIKMAMQRNLCTLELFSV 13053

Query: 900   SETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDK 959
             +     + T   + ++    SKS  +K K     P PP  +   + + D  +L W+ P +
Sbjct: 13054 NRKDSGDYTITAENSSG---SKSATIKLKV-LDKPGPPASVKINKMYSDRAMLSWEPPLE 13109

Query: 960   IGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GG+EIT Y V+ RE        W + +   V   +  +  L E   YQF++ A N  G+
Sbjct: 13110 DGGSEITNYIVDKRETSRP---NWAQVSA-TVPITSCSVEKLIEGHEYQFRICAENKYGV 13165

Query: 1020  GAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
             G P           +    PG       S + KD + + WKPP   G +P+TGY ++ +E
Sbjct: 13166 GDPVFTEPAIAKNPYD--PPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRE 13223

Query: 1080  AKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              +A    W  +N   I    LK  GL+EG  Y FRV AIN+AG GKPSD
Sbjct: 13224 TQAVN--WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 13270



 Score =  235 bits (600), Expect = 2e-61
 Identities = 248/1071 (23%), Positives = 420/1071 (39%), Gaps = 153/1071 (14%)

Query: 294   VKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRAS 353
             V+L   IAG P P  +W+     +       +  +E+   +  L I      DT +Y   
Sbjct: 23451 VELVIPIAGRPPPAASWFFAGSKLR---ESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23507

Query: 354   AMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDV 413
               NV G  S    V++    G                     P G     EI   D   +
Sbjct: 23508 LKNVTGTTSETIKVIILDKPGP--------------------PTGPIKIDEI---DATSI 23544

Query: 414   SFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLN 473
             +   E   +  G      P   +   +   +R G       W+    S  R+T  F+ L 
Sbjct: 23545 TISWEPPELDGGA-----PLSGYVVEQRDAHRPG-------WLPVSESVTRSTFKFTRLT 23592

Query: 474   KEDEGLYTI----RVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIIS 529
             + +E ++ +    R  +G Y +       V +  + I   P  P  ++  + ++D + ++
Sbjct: 23593 EGNEYVFRVAATNRFGIGSYLQSE-----VIECRSSIR-IPGPPETLQIFDVSRDGMTLT 23646

Query: 530   WKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNK 589
             W  P  DGGS + GY +++ EV  D W + N  PV   R+  TGL EG  Y  RV A+N 
Sbjct: 23647 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 23706

Query: 590   MGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEA 649
              G G PSR S+P+ A+DP           AP                 PG P +  VT+ 
Sbjct: 23707 RGSGKPSRPSKPIVAMDPI----------AP-----------------PGKPQNPRVTDT 23739

Query: 650   TRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSY 708
             TR+ V L+W  P   G   +  Y +E  +     W + NT  P K   + L  L +G  Y
Sbjct: 23740 TRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTT-PTKIREYTLTHLPQGAEY 23798

Query: 709   CFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKEL 768
              FRV   N+ G GEP+E      V + L+ P            D  +   ++E    ++ 
Sbjct: 23799 RFRVLACNAGGPGEPAEVPGTVKVTEMLEYP------------DYELDERYQEGIFVRQ- 23845

Query: 769   VGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLV-TGQSYIFRVRAVNAAGLS------- 820
              G  I  ++   GK  P      +G   +   ++ T +++   V      G S       
Sbjct: 23846 -GGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVL 23904

Query: 821   EYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPN 880
             E     +A+ +K  + G  +    P   D+   +     RV    P       +LG    
Sbjct: 23905 ENKCGKKAVYIKVRVIGSPNSPEGPLEYDD---IQVRSVRVSWRPPADDGGADILGYILE 23961

Query: 881   KPSLPSSSQNLGQTEVSKVSETVQE---------ELTPPPQKAAPQGKSKSDPLKKKTDR 931
             +  +P ++     + V   S  V+           ++   Q    +     +P+  KT  
Sbjct: 23962 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 24021

Query: 932   APPSPPCDIT-CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKA 990
              PP PP +    L+  + S+ L W +P   GG+ +TGYY+  +E       KW   N   
Sbjct: 24022 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD---KWVRHNKTQ 24078

Query: 991   VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEV 1050
             ++   Y ++ L  +  YQF++ A N  GL   S  SE   C++     P  P  L+   +
Sbjct: 24079 ITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD-PFDKPSQPGELEILSI 24137

Query: 1051  RKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVS 1110
              KDS+ LQW+ P   G   + GY+V+ ++  + +  W+  N+  IK+    + GL E   
Sbjct: 24138 SKDSVTLQWEKPECDGGKEILGYWVEYRQ--SGDSAWKKSNKERIKDKQFTIGGLLEATE 24195

Query: 1111  YVFRVRAINQAGVGKPSDLAGPV----VAETRPGTKEVVVNVDDDGVISLNFECDKM-TP 1165
             Y FRV A N+ G+ +P   A  +     +   PG ++ + +V      +    C  +  P
Sbjct: 24196 YEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRP 24255

Query: 1166  KSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLID 1225
               +  W +       S + ++ S G    +T      +D G+Y+C       IA++ + +
Sbjct: 24256 LPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC-------IATNEVGE 24308

Query: 1226  EEELKRLLALSHEHKFPTVPVK--------SELAVEILEKGQ---VRFWMQAEKLSGNAK 1274
              E   +LL  +     P  P+K        S L + ++  G+      W   +KL  N++
Sbjct: 24309 VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 24368

Query: 1275  VNYIFNEKEI-----------FEGPKYKMHIDRNTGIIEMFME-KLQDEDE 1313
                I N +                 KYK+ +    G ++  ++ ++QD+ +
Sbjct: 24369 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPD 24419



 Score =  234 bits (597), Expect = 5e-61
 Identities = 319/1304 (24%), Positives = 521/1304 (39%), Gaps = 194/1304 (14%)

Query: 273   LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY 332
             L+  P F +   + TV   E++K+     G P P VTW+K+ VP+       +   ES  
Sbjct: 15839 LVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK---QTTRVNAESTE 15895

Query: 333   GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKG------EFDETRFHAGAS 386
                 L I     ED   Y     N  GE     +V+V    G      + DE      A 
Sbjct: 15896 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVT----AD 15951

Query: 387   TMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRN 446
             ++ LS+G   Y   S    +  +K D S                                
Sbjct: 15952 SITLSWGPPKYDGGSSINNYIVEKRDTS-------------------------------- 15979

Query: 447   GVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAE- 505
                   + W     +  R T+    L    E  Y  R+     Y + S Y+      A+ 
Sbjct: 15980 -----TTTWQIVSATVARTTIKACRLKTGCE--YQFRIAAENRYGK-STYLNSEPTVAQY 16031

Query: 506   ---IEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDT 562
                + G P  P+      +++D + + W +P  DGGS ++GY +++ E  +  W + N T
Sbjct: 16032 PFKVPGPPGTPVVTL---SSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKT 16088

Query: 563   PVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWT 622
             P+   +F  TGL EG  Y FRV A N +GIG PS+VSE   A DP +             
Sbjct: 16089 PIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDP------------ 16136

Query: 623   GQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTE 681
                            PG P  + VT   R+ V L WK P   G   I  Y VEK E    
Sbjct: 16137 ---------------PGRPEAIIVT---RNSVTLQWKKPTYDGGSKITGYIVEKKELPEG 16178

Query: 682   NWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV-GEPSEATEVTVVGDKLDIPK 740
              W + +    + +  F +  L E   Y FRV   N+AGV  EPSE+T      D++D P+
Sbjct: 16179 RWMKASFTNIIDT-HFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16237

Query: 741   APGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNN--PVKGSRF-- 796
                  +  +  DT VV + E  K   ++ G  I       G  E  N     +K + F  
Sbjct: 16238 IS---MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFAT 16294

Query: 797   --TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGL 854
               +    V   S  + ++A N AG     + S  + VK     G  P   P +     G+
Sbjct: 16295 SLSVKDAVRVDSGNYILKAKNVAG-----ERSVTVNVKVLDRPG--PPEGPVVIS---GV 16344

Query: 855   TASRGRVHEASPPTFQKDA------LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQ-EEL 907
             TA +  +  A  P  Q         ++  +     + +      QT   KV++ ++  E 
Sbjct: 16345 TAEKCTL--AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEY 16402

Query: 908   TPPPQKAAPQGKSK---SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
             T         G  +   S+P+  K     P  P         +DSM++ W++P   GG+E
Sbjct: 16403 TFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSE 16462

Query: 965   ITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSA 1024
             I GY +  R+  +G+  +W   + + + E   +++ L EN  Y+F+V+A N AGL  PS 
Sbjct: 16463 ILGYVLEKRDK-EGI--RWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSP 16519

Query: 1025  VSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE 1084
              S   K  +  I  PGPP++ K  ++ + S+ L W  P++ G   + GY V+  +    E
Sbjct: 16520 PSAYQKACD-PIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGE 16578

Query: 1085  DQWRGLNE-AAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKE 1143
               W        I    ++V  L E   Y FR+ AIN+AGVG+ +D+ GP++ E +    +
Sbjct: 16579 --WTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPD 16636

Query: 1144  V--------VVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKM 1195
             +        ++N+   G + L F   K  P  E  W K      D+  ++V S  + T +
Sbjct: 16637 IDLDLELRKIINIRAGGSLRL-FVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSL 16693

Query: 1196  TFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEIL 1255
                ++   D G Y+  + ++ G  S+++       R+L        P+ PV   L V  +
Sbjct: 16694 VLDNVNRYDSGKYTLTLENSSGTKSAFV-----TVRVL------DTPSPPV--NLKVTEI 16740

Query: 1256  EKGQVRFWMQAEKLSGNAKV-NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEG 1314
              K  V    +   L G +K+ NYI  ++E     K    +  N       +++LQ   EG
Sbjct: 16741 TKDSVSITWEPPLLDGGSKIKNYIVEKREATR--KSYAAVVTNCHKNSWKIDQLQ---EG 16795

Query: 1315  -TYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECN 1373
              +Y F++    A N   + L       + K AE           P     ++ +     +
Sbjct: 16796 CSYYFRV---TAENEYGIGLPAQTADPI-KVAEV----------PQPPGKITVDDVTRNS 16841

Query: 1374  VLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTL--LITEFSKKDAGIYEVILK 1431
             V L          + I+ Y  E +    EK      + +L  +IT  ++ +  ++ V+  
Sbjct: 16842 VSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAV 16901

Query: 1432  DDRGKDKSRLKLVDEAFKELMMEVCKKIALSA------TDLKIQSTAEGIQLYSFVTYYV 1485
             +++G+   R   V    K+L++E   K A S+       DLKI+    G    +      
Sbjct: 16902 NEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPT------ 16955

Query: 1486  EDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY 1529
                 + W+ +G  ++ + R+    + +   L I E   +D G+Y
Sbjct: 16956 ----ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16995



 Score =  233 bits (595), Expect = 9e-61
 Identities = 261/1020 (25%), Positives = 403/1020 (39%), Gaps = 115/1020 (11%)

Query: 237   EKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKL 296
             E+K R  ++  K  +  +  T  + +     +  +  ++A   +   ++    E    + 
Sbjct: 17155 ERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARD 17214

Query: 297   HCSIAGWPEPRVTWYKNQVPIN----VHANPGK---YIIESRYGMHTLEINGCDFEDTAQ 349
              C   G PEP +   +N++ +     V+        YI+E R           D  D   
Sbjct: 17215 PCDPPGTPEP-IMVKRNEITLQWTKPVYDGGSMITGYIVEKR-----------DLPDGRW 17262

Query: 350   YRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFE---IH 406
              +AS  NV  E     S + +  + EF     +A  +    S    P       E   I 
Sbjct: 17263 MKASFTNVI-ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRIS 17321

Query: 407   FDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERA 465
              D KF D      GET  L   V   P      P I+W R    +  S   +   +  +A
Sbjct: 17322 MDPKFRDTIVVNAGETFRLEADVHGKP-----LPTIEWLRGDKEIEESARCEIKNTDFKA 17376

Query: 466   TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
              L      + D G Y +R       + +   V V D      G P  P+ V  + + K  
Sbjct: 17377 LLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQVTGVTSEK-- 17430

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
               ++W  P  DGGS I  Y ++K E    +W+      V  +   VT L+EG  Y+FR+ 
Sbjct: 17431 CSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNS-LKVTKLLEGNEYVFRIM 17489

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             AVNK G+G P   S PV   +P                            ++PGPP  L 
Sbjct: 17490 AVNKYGVGEPLE-SAPVLMKNPF---------------------------VLPGPPKSLE 17521

Query: 646   VTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAE 704
             VT   +  + + W +P    G E I Y VEK +     W + N    +   R  +  L E
Sbjct: 17522 VTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRR-ITDLRLRVTGLTE 17580

Query: 705   GKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-- 762
                Y FRV   N+AGVGEPS AT      D +  P  P        T  S+ ++W +   
Sbjct: 17581 DHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIY 17640

Query: 763   KDAKELVGYYIEASVAGSGKWEPCN-NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSE 821
                 E++GY +E   A   +W+       ++ +RF    L   Q Y  RV A+N  GL E
Sbjct: 17641 DGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGE 17700

Query: 822   YSQDSEAIEVKAAIGGGVSPD---VCPAL---SDEPGGLTASRG---RVH---EASP-PT 868
                         ++ G V P+     P L   S+   G+    G   R+H   +  P P 
Sbjct: 17701 ----------ATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPE 17750

Query: 869   FQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKK 928
                    G   +K  +    + +  T++S +    + +      K      SKS  +  K
Sbjct: 17751 ITWSREEGEFTDKVQI---EKGVNYTQLS-IDNCDRNDAGKYILKLENSSGSKSAFVTVK 17806

Query: 929   TDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
                  P PP ++   E  +DS  L W+ P   GGA++  Y ++ RE       +   ANV
Sbjct: 17807 V-LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE-----STRKAYANV 17860

Query: 989   KA-VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKC 1047
              +  S+ ++K+ NL E  +Y F+V A N  G+G P    +  K  E     P PP  +  
Sbjct: 17861 SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAE----PPSPPGKVTL 17916

Query: 1048  SEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKE 1107
             ++V + S  L W+ P H G + V GY V+++      ++W  + E+ + N    V GL  
Sbjct: 17917 TDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGT--EKWSIVAESKVCNAV--VTGLSS 17972

Query: 1108  GVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVVNVDDDGVISLNFECDKM- 1163
             G  Y FRV+A N+ G   P  L  PV+A+    +P  K             L  E   + 
Sbjct: 17973 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIG 18032

Query: 1164  TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
              P+   SW KD    + + R+ VE     T +  K+   DD G Y+   T++ G A+  L
Sbjct: 18033 RPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENL 18092



 Score =  233 bits (594), Expect = 1e-60
 Identities = 253/971 (26%), Positives = 389/971 (40%), Gaps = 143/971 (14%)

Query: 290   EKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQ 349
             E  N +L   I G P P V+W K + P+   A   +  +ES     TL +  C   D  +
Sbjct: 13691 ENSNFRLKIPIKGKPAPSVSWKKGEDPL---ATDTRVSVESSAVNTTLIVYDCQKSDAGK 13747

Query: 350   YRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFG-VTPYGYASRFEIHFD 408
             Y  +  NV G      S+ V              G  T P+ F  VT      ++    D
Sbjct: 13748 YTITLKNVAGTKEGTISIKVVG----------KPGIPTGPIKFDEVTAEAMTLKWAPPKD 13797

Query: 409   DKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLT 468
             D      G E           IT  I   +  +           +KWV    + ++ T  
Sbjct: 13798 DG-----GSE-----------ITNYILEKRDSVN----------NKWVTCASAVQKTTFR 13831

Query: 469   FSHLNKEDEGLYTIRVRMGEYY---EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
              + L++  E  YT RV     Y   E   +   V     ++  AP  P     ++   D 
Sbjct: 13832 VTRLHEGME--YTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPP---NIVDVRHDS 13886

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
             + ++W  P   GGSPI GY ++  E  +  W + N TP++   F VTGL EG  Y FRV 
Sbjct: 13887 VSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVM 13946

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             A+N  G+G PS  SEPV ALDP +                              PP    
Sbjct: 13947 AINLAGVGKPSLPSEPVVALDPID------------------------------PPGKPE 13976

Query: 646   VTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAE 704
             V   TR+ V L W +P    GH+   Y VEK +  +++W + N  + V    F + DL E
Sbjct: 13977 VINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKAN-HVNVPECAFTVTDLVE 14035

Query: 705   GKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESK 763
             G  Y FR+R  N+AG +  PSE+TE  +  D+ +   AP  ++     D   +    ++ 
Sbjct: 14036 GGKYEFRIRAKNTAGAISAPSESTETIICKDEYE---APTIVLDPTIKDGLTI----KAG 14088

Query: 764   DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823
             D   L    I         W     + ++ S  T     T  S +  ++        EY+
Sbjct: 14089 DTIVLNAISILGKPLPKSSWSKAGKD-IRPSDIT-QITSTPTSSMLTIKYATRKDAGEYT 14146

Query: 824   QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPS 883
                  I      G  V   V   + D PG      G V E S  + +K  L  + P +  
Sbjct: 14147 -----ITATNPFGTKVE-HVKVTVLDVPG----PPGPV-EISNVSAEKATLTWTPPLEDG 14195

Query: 884   -LPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQ-----------------GKSK---S 922
               P  S  L + E S++  TV  E     +  A +                 GK +   S
Sbjct: 14196 GSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQS 14255

Query: 923   DPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGK 982
             +P+K      PP PP         +++  + WK+P   GG+EITGY+V  RE       +
Sbjct: 14256 EPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSL---R 14312

Query: 983   WREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPP 1042
             W  A    VS+   K++ L+E   Y+F+V+A N AG+G PS  S+    ++     PGPP
Sbjct: 14313 WVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD-AAYPPGPP 14371

Query: 1043  HSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW-RGLNEAAIKNVYLK 1101
              +   ++  K S  L W  P + G   +TGY V+    K  ++ W +     A++     
Sbjct: 14372 SNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVE--HQKVGDEAWIKDTTGTALRITQFV 14429

Query: 1102  VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG---------TKEVVVNVDDDG 1152
             V  L+    Y FR+ AIN AGVG+P+ +    + E              + +VV     G
Sbjct: 14430 VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRA---G 14486

Query: 1153  VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
             +    F   K  P  E +W+KD ++ ++  R  +E+  + T +   +    D G +   +
Sbjct: 14487 LSIRIFVPIKGRPAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTGKFVMTI 14544

Query: 1213  TDTDGIASSYL 1223
              +  G  S ++
Sbjct: 14545 ENPAGKKSGFV 14555



 Score =  233 bits (593), Expect = 2e-60
 Identities = 236/910 (25%), Positives = 381/910 (41%), Gaps = 117/910 (12%)

Query: 404   EIHFDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG 462
             +I  D KF D    + GE   L   V   P      P ++W ++G  L  +  ++   + 
Sbjct: 15155 KIKVDVKFKDTVILKAGEAFRLEADVSGRPP-----PTMEWSKDGKELEGTAKLEIKIAD 15209

Query: 463   ERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEAN 522
                 L      + D G YT+       + ++   V V D      G P  PL V   E  
Sbjct: 15210 FSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRP----GPPEGPLAVT--EVT 15263

Query: 523   KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIF 582
              +  ++SW  P  DGG+ I  Y + K E    +W+    + V+  +  VT L++G  YIF
Sbjct: 15264 SEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIF 15322

Query: 583   RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
             RV AVNK G+G P   SEPV A++P                              P PP 
Sbjct: 15323 RVMAVNKYGVGEPLE-SEPVLAVNPYGP---------------------------PDPPK 15354

Query: 643   DLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFD 701
             +  VT  T+  +V+ W  P    G E I Y VE+ +   + W + N +  +   R+ +  
Sbjct: 15355 NPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT-LTDLRYKVSG 15413

Query: 702   LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEE 761
             L EG  Y FR+   N+AG+  PS  +      D +  P  PG       + +S+ ++W +
Sbjct: 15414 LTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNK 15473

Query: 762   S--KDAKELVGYYIEASVAGSGKWEPCNNNP-VKGSRFTCHGLVTGQSYIFRVRAVNAAG 818
                    E+ GY +E ++    +W+       +K + +T  GL   Q Y  R+ A+N+ G
Sbjct: 15474 PIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEG 15533

Query: 819   LSE--------YSQDS---EAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPP 867
             L E         ++D      IE+ A +   V+   C  L          +GR   A   
Sbjct: 15534 LGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRL----FVPIKGR--PAPEV 15587

Query: 868   TFQKDALLGSKPNKPSLPSSSQ-------NLGQTEVSKVSETVQEELTPPPQKAAPQGKS 920
              + +D   G   +K S+ S+S        N+ + +  K   TV+               S
Sbjct: 15588 KWARDH--GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENS-----------SGS 15634

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
             KS  +  +     P PP D+   E  + S+ L W  P   GG++I  Y V  RE      
Sbjct: 15635 KSAFVNVRV-LDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTR--- 15690

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
              K          + ++K+  L+E   Y F+V A N  G+G P+  +E  K  E     P 
Sbjct: 15691 -KAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASER----PL 15745

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYL 1100
             PP  +   +V ++S+ L W+ P H G + + GY V+++   +  D+W     A +K    
Sbjct: 15746 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGS--DKWATC--ATVKVTEA 15801

Query: 1101  KVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR--PGTKEVVVNV-----DDDGV 1153
              + GL +G  Y FRV A N+ G+  P  L+ PV+A+    P   +++ N       +D  
Sbjct: 15802 TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLK 15861

Query: 1154  ISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVT 1213
             + + F   + TP    +W KD V  + + R+  ES  N + +T KD   +D+G Y   +T
Sbjct: 15862 VDVPF-IGRPTPA--VTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLT 15918

Query: 1214  DTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
             ++ G A        E   ++ L      PT PVK +   E+        W   +   G++
Sbjct: 15919 NSAGEAI-------ETLNVIVLDKPGP-PTGPVKMD---EVTADSITLSWGPPKYDGGSS 15967

Query: 1274  KVNYIFNEKE 1283
               NYI  +++
Sbjct: 15968 INNYIVEKRD 15977



 Score =  232 bits (592), Expect = 2e-60
 Identities = 212/734 (28%), Positives = 309/734 (42%), Gaps = 93/734 (12%)

Query: 439  PEIQWYRNGVPLS-PSKWVQTLW-----SGERATLTFSHLNKEDEGLYTIRV--RMGEYY 490
            P+I+W +N   +  P+  +Q        S  +  L+     +ED+G YT+    R+G  +
Sbjct: 9123 PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVF 9182

Query: 491  EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCE 550
                     R+   E+   P+ P ++   +   +   ++W  P  +GGS I  Y IDK +
Sbjct: 9183 ---------RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRD 9233

Query: 551  VGTD--SWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPA 608
                   W +  +T V+  R+ +  LI    Y FRVRAVNK GI    + S+ V   DP 
Sbjct: 9234 ASRKKAEWEEVTNTAVE-KRYGIWKLIPNGQYEFRVRAVNKYGISDECK-SDKVVIQDPY 9291

Query: 609  EKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEG 668
                                        +PGPP    V   T+  +++SW PP   G   
Sbjct: 9292 R---------------------------LPGPPGKPKVLARTKGSMLVSWTPPLDNGGSP 9324

Query: 669  IM-YFVEKCEAGTENWQRVN----TELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEP 723
            I  Y++EK E G+  W RV+    T++ +K   F +  L EG  Y FR    N+AG+G P
Sbjct: 9325 ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPP 9384

Query: 724  SEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE-ESKD-AKELVGYYIEASVAGSG 781
            SE ++  V GD +  P  P        T +S+ + W+  +KD    + GY +E    G+ 
Sbjct: 9385 SEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTT 9444

Query: 782  KWEPCNNNPVKGSRFTCHGLVTG----QSYIFRVRAVNAAGLSEYSQDSEAI-------E 830
             W+   N P K    TC  +V      + Y FRV+AVN AG SE S  +  I       E
Sbjct: 9445 DWKRV-NEPDK-LITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEE 9502

Query: 831  VKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQN 890
             +  I  G    +      +       +GR    S   F   A    K     +P  +Q 
Sbjct: 9503 PEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQ- 9561

Query: 891  LGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAP---------PSPPCDIT 941
            L   E S V       +  P  K +  GK       K   +           P PP D+ 
Sbjct: 9562 LETAENSSV-------IIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK 9614

Query: 942  CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
              +  R S  L WK PD  GG  I GY +  R  IDG    W + N    S   + + +L
Sbjct: 9615 VSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR-TIDG--KAWTKVNPDCGS-TTFVVPDL 9670

Query: 1002 KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
                 Y F+V A N  G+G P    +     +  I  P PP  LK   + K+++ L WKP
Sbjct: 9671 LSEQQYFFRVRAENRFGIGPPVETIQRTTARD-PIYPPDPPIKLKIGLITKNTVHLSWKP 9729

Query: 1062 PVHSGRTPVTGYFVDL---KEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAI 1118
            P + G +PVT Y V+         K++ WR  N+  ++ +   V  L EG  Y FRV+A+
Sbjct: 9730 PKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAV 9789

Query: 1119 NQAGVGKPSDLAGP 1132
            N AGV KPS   GP
Sbjct: 9790 NAAGVSKPSATVGP 9803



 Score =  228 bits (582), Expect = 3e-59
 Identities = 213/797 (26%), Positives = 332/797 (41%), Gaps = 96/797 (12%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVR--MGEYYEQYSAY 496
             P+  W + G  + PS   Q   +   + LT  +  ++D G YTI      G   E     
Sbjct: 14104 PKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVT 14163

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             V       ++ G P  P+++  + A K    ++W  P  DGGSPI  Y ++K E     W
Sbjct: 14164 VL------DVPGPPG-PVEISNVSAEK--ATLTWTPPLEDGGSPIKSYILEKRETSRLLW 14214

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             +  ++  ++  R   T LI+G  YIFRV AVN  G G P + SEPV  +D       +  
Sbjct: 14215 TVVSED-IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVD-------RFG 14265

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
             P                    PGPP    V+  T++   +SWK P   G   I  Y VE+
Sbjct: 14266 P--------------------PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVER 14305

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  W R   + PV   R  +  L EG +Y FRV   N AG+G PSEA++  ++ D 
Sbjct: 14306 REKKSLRWVRA-IKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA 14364

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEESK--DAKELVGYYIEASVAGSGKW-EPCNNNPVK 792
                P  P     +  T  S  ++W +       E+ GY +E    G   W +      ++
Sbjct: 14365 AYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALR 14424

Query: 793   GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS--QDSEAIEVKAAIGGGVSPDVCPALSDE 850
              ++F    L T + Y FR+ A+N AG+ E +   D E +E + A    +  ++   L   
Sbjct: 14425 ITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVR 14484

Query: 851   PGG----LTASRGRVHEASPPTFQKDAL-LGSKPNKPSLPSSS----QNLGQTEVSKVSE 901
              G         +GR   A   T+ KD + L ++ N  +  S +        + +  K   
Sbjct: 14485 AGLSIRIFVPIKGR--PAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 14542

Query: 902   TVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIG 961
             T++           P GK       +  D   P P  ++   +  +DS+ L W  P   G
Sbjct: 14543 TIEN----------PAGKKSGFVNVRVLDT--PGPVLNLRPTDITKDSVTLHWDLPLIDG 14590

Query: 962   GAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGA 1021
             G+ IT Y V  RE        +  A  K   +  YK++ L E   Y F+V A N  G+G 
Sbjct: 14591 GSRITNYIVEKREA---TRKSYSTATTKC-HKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14646

Query: 1022  PSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAK 1081
             P+  +E  K  E     P PP SL   ++ K ++ L W  P H G + +TGY ++ +  +
Sbjct: 14647 PTETTEPVKASE----APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQ--R 14700

Query: 1082  AKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGT 1141
                DQW  +    +K +   VR L EG  Y F+V A+N AG   P + + PV+ + +   
Sbjct: 14701 KGSDQWTHI--TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPVIVKEQTML 14757

Query: 1142  KE----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGN 1191
              E          V+    D+  + +        PK   +W K     + + R+  E+   
Sbjct: 14758 PELDLRGIYQKLVIAKAGDNIKVEIPV---LGRPKPTVTWKKGDQILKQTQRVNFETTAT 14814

Query: 1192  KTKMTFKDLGMDDLGIY 1208
              T +   +    D G Y
Sbjct: 14815 STILNINECVRSDSGPY 14831



 Score =  227 bits (579), Expect = 6e-59
 Identities = 229/893 (25%), Positives = 362/893 (40%), Gaps = 102/893 (11%)

Query: 425   GCRVVITPEIKHFQ-PEIQWYR-------NGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             G  V I  +IK    P + W++       N  P+     V  L   +  TL      + D
Sbjct: 9826  GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9885

Query: 477   EGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPA 534
              GLYTI     +G   ++    V  R       G P  P+  + + A  D + +SW  P 
Sbjct: 9886  TGLYTITAVNNLGTASKEMRLNVLGRP------GPPVGPIKFESVSA--DQMTLSWFPPK 9937

Query: 535   VDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGF 594
              DGGS I  Y I+K E    +W   +  P K   + +  L+EG  Y+FR+ A NK GIG 
Sbjct: 9938  DDGGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9996

Query: 595   PSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYV 654
             P         LD           S P T + + +        VPG P   +V+  TR+ +
Sbjct: 9997  P---------LD-----------SEPETARNLFS--------VPGAPDKPTVSSVTRNSM 10028

Query: 655   VLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR----FALFDLAEGKSYC 709
              ++W+ P   G   +  Y++E  +  ++ W+RVN + P+K+      + +  L EG  Y 
Sbjct: 10029 TVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRD-PIKAMTLGVSYKVTGLIEGSDYQ 10087

Query: 710   FRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-KDA-KE 767
             FRV   N+AGVG  S  ++     D +  P  P   +    T +S  + W    KD   +
Sbjct: 10088 FRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW-TKSSADLEWSPPLKDGGSK 10146

Query: 768   LVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 827
             + GY +E    G  +WE   +  V+G++    GL  G  Y FRVRAVN AG+ E  + ++
Sbjct: 10147 VTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD 10206

Query: 828   AIEVKAAIGGGVSPD------VCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNK 881
              IE+K  +   VSPD      V   +    GG+      V    PPT   +    + P +
Sbjct: 10207 VIEMKDRL---VSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQE 10263

Query: 882   PSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDIT 941
              ++ +++  +  + V K  +   + +     K     + K+  +       P   P    
Sbjct: 10264 ATIETTA--ISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTP--FL 10319

Query: 942   CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
                   +S  L W  P+  GG+ IT Y +  RE        W         + A  +  L
Sbjct: 10320 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRE---SDRRAWTPVTYTVTRQNA-TVQGL 10375

Query: 1002  KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
              +   Y F++AA N  G+G     SE     E  I VP  P  L+  EV K+++ L W P
Sbjct: 10376 IQGKAYFFRIAAENSIGMGPFVETSEALVIRE-PITVPERPEDLEVKEVTKNTVTLTWNP 10434

Query: 1062  PVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA 1121
             P + G + +  Y ++       E   +  N+  +   Y  V+GLKEG +Y +RV A+N  
Sbjct: 10435 PKYDGGSEIINYVLE-SRLIGTEKFHKVTNDNLLSRKY-TVKGLKEGDTYEYRVSAVNIV 10492

Query: 1122  GVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMT------PKSEFSWSKDY 1175
             G GKPS    P+  +       + ++  D   I +  E   +T      PK + SW KD 
Sbjct: 10493 GQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVG-EAFALTGRYSGKPKPKVSWFKDE 10551

Query: 1176  VSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSY----LIDEEELKR 1231
                 +  R  +++      +        D G Y   V ++ G    +    ++D      
Sbjct: 10552 ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR----- 10606

Query: 1232  LLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEI 1284
                       P  PV      E+ +   V  W       G+   NYI  +KE+
Sbjct: 10607 ----------PGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEV 10649



 Score =  225 bits (574), Expect = 2e-58
 Identities = 218/877 (24%), Positives = 354/877 (40%), Gaps = 106/877 (12%)

Query: 367   VVVKRYKGEFDETRFHAGASTM-----PLSFGVTPYGYASRFEIHFDDKFDVSFGREGET 421
             V+ +   G F E     GA T      P    + P  Y     +H  + F V     G+ 
Sbjct: 16208 VIARNAAGVFSEPSESTGAITARDEVDPPRISMDPK-YKDTIVVHAGESFKVDADIYGKP 16266

Query: 422   MSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYT 481
             +                P IQW +    LS +  ++   +    +L+     + D G Y 
Sbjct: 16267 I----------------PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYI 16310

Query: 482   IRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPI 541
             ++ +        +  V V D      G P  P+ +  + A K    ++WK P  DGGS I
Sbjct: 16311 LKAKNVAGERSVTVNVKVLDRP----GPPEGPVVISGVTAEK--CTLAWKPPLQDGGSDI 16364

Query: 542   LGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEP 601
             + Y +++ E     W+   D  V+     VT L+EG  Y FR+ AVNK G+G P   SEP
Sbjct: 16365 INYIVERRETSRLVWTVV-DANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE-SEP 16422

Query: 602   VAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPP 661
             V A +P                            +VP  P    VT  T+  +++ W+ P
Sbjct: 16423 VVAKNPF---------------------------VVPDAPKAPEVTTVTKDSMIVVWERP 16455

Query: 662   GQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV 720
                G   I+ Y +EK +     W R +  L +   R  +  L E   Y FRV   N+AG+
Sbjct: 16456 ASDGGSEILGYVLEKRDKEGIRWTRCHKRL-IGELRLRVTGLIENHDYEFRVSAENAAGL 16514

Query: 721   GEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVA 778
              EPS  +      D +  P  P        T +SV +SW +       E+ GY +E    
Sbjct: 16515 SEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDV 16574

Query: 779   GSGKWEPCNN-NPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGG 837
               G+W  C     +  +      L+    Y FR+ A+N AG+ E++     I V+  +  
Sbjct: 16575 SVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEA 16634

Query: 838   ---GVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQ----- 889
                 +  ++   ++   GG       +     P  +   + G   +   +  +S      
Sbjct: 16635 PDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV 16694

Query: 890   --NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFR 947
               N+ + +  K + T++             G   +    +  D   PSPP ++   E  +
Sbjct: 16695 LDNVNRYDSGKYTLTLENS----------SGTKSAFVTVRVLDT--PSPPVNLKVTEITK 16742

Query: 948   DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY 1007
             DS+ + W+ P   GG++I  Y V  RE       K   A V    + ++KI  L+E   Y
Sbjct: 16743 DSVSITWEPPLLDGGSKIKNYIVEKREATR----KSYAAVVTNCHKNSWKIDQLQEGCSY 16798

Query: 1008  QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 1067
              F+V A N  G+G P+  ++  K  E    VP PP  +   +V ++S+ L W  P H G 
Sbjct: 16799 YFRVTAENEYGIGLPAQTADPIKVAE----VPQPPGKITVDDVTRNSVSLSWTKPEHDGG 16854

Query: 1068  TPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS 1127
             + +  Y V++ +AK  E +W     A +K++   +  L +G  Y+FRV A+N+ G   P 
Sbjct: 16855 SKIIQYIVEM-QAKHSE-KWSEC--ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPR 16910

Query: 1128  DLAGPVVA-------ETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTED 1180
              LA P+VA       + +P      V V  D  I +        PK   +W+KD +  + 
Sbjct: 16911 SLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG---RPKPTITWTKDGLPLKQ 16967

Query: 1181  SPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             + R+ V    + T ++ K+   DD G Y   V +  G
Sbjct: 16968 TTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG 17004



 Score =  224 bits (572), Expect = 4e-58
 Identities = 288/1312 (21%), Positives = 517/1312 (39%), Gaps = 206/1312 (15%)

Query: 276   APEFIIKP------RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIE 329
             A + +I+P       S++V   +++K+   I+G P+P +TW K+ +P+       +  + 
Sbjct: 16918 AKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK---QTTRINVT 16974

Query: 330   SRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRY----KG--EFDETRFHA 383
                 + TL I     +D  QY  +  NV G+ +A   +V        KG  +FD+     
Sbjct: 16975 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDV---- 17030

Query: 384   GASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQW 443
              A ++ LS+    Y    +   +   K D +                             
Sbjct: 17031 SAESITLSWNPPLYTGGCQITNYIVQKRDTT----------------------------- 17061

Query: 444   YRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV---FVR 500
                      + W     +  R TL  + L    E  Y  R+     Y Q  A      V 
Sbjct: 17062 --------TTVWDVVSATVARTTLKVTKLKTGTE--YQFRIFAENRYGQSFALESDPIVA 17111

Query: 501   DADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCN 560
                 +  G P  P        +KD ++I W +P  +GGSP++GY +++ E  +  W++ N
Sbjct: 17112 QYPYKEPGPPGTPF---ATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVN 17168

Query: 561   DTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAP 620
              T +   +F    L EG  Y FRV A N +G+G  S+ SE   A DP +           
Sbjct: 17169 KTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDP---------- 17218

Query: 621   WTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAG 679
                              PG P  + V    R+ + L W  P   G   I  Y VEK +  
Sbjct: 17219 -----------------PGTPEPIMVK---RNEITLQWTKPVYDGGSMITGYIVEKRDLP 17258

Query: 680   TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDI 738
                W + +    +++ +F +  L E + Y FRV   N+AG + +PS++T      D++++
Sbjct: 17259 DGRWMKASFTNVIET-QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVEL 17317

Query: 739   PKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEAS--VAGSGKWEPCNNNPVKGSRF 796
             P+     +  +  DT VV + E  +   ++ G  +     + G  + E      +K + F
Sbjct: 17318 PRIS---MDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17374

Query: 797   TCHGLVT------GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGG-----GVSPDVC- 844
                 +V       G  YI  +RA N AG   +  + + ++      G     GV+ + C 
Sbjct: 17375 KALLIVKDAIRIDGGQYI--LRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17432

Query: 845   ----PALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVS 900
                 P L D  GG   S   V +          ++ S+    SL  +    G   V ++ 
Sbjct: 17433 LTWSPPLQD--GGSDISHYVVEKRETSRLAW-TVVASEVVTNSLKVTKLLEGNEYVFRIM 17489

Query: 901   ETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKI 960
                +  +  P + A         P+  K     P PP  +      +DSM + W +PD  
Sbjct: 17490 AVNKYGVGEPLESA---------PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSD 17540

Query: 961   GGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLG 1020
             GG+EI GY V  R+   G+  +W + N + +++   +++ L E+  Y+F+V+A N AG+G
Sbjct: 17541 GGSEIIGYIVEKRD-RSGI--RWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVG 17597

Query: 1021  APSAVSECFK-CEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
              PS  +  +K C+   +  PGPP +    +  K+S+ L W  P++ G + + GY V++  
Sbjct: 17598 EPSPATVYYKACD--PVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEI-- 17653

Query: 1080  AKAKEDQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR 1138
              KA E++W+ +  +  ++    ++  L E   Y  RV A+N+ G+G+ + + G V  E +
Sbjct: 17654 CKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDK 17713

Query: 1139  PGTKE----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVES 1188
                 E          +VV       I + F   K  P  E +WS++    E + ++++E 
Sbjct: 17714 LEAPELDLDSELRKGIVVRAGGSARIHIPF---KGRPTPEITWSRE--EGEFTDKVQIEK 17768

Query: 1189  KGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKS 1248
               N T+++  +   +D G Y   + ++ G  S+++  +                T     
Sbjct: 17769 GVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVK-------------VLDTPGPPQ 17815

Query: 1249  ELAVEILEKGQVRFWMQAEKLSGNAKV-NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEK 1307
              LAV+ + K       +   + G AKV NY+ +++E     K   ++          +E 
Sbjct: 17816 NLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE--STRKAYANVSSKCSKTSFKVEN 17873

Query: 1308  LQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWE 1367
             L   +   Y F++           V   D  K  +               P     ++  
Sbjct: 17874 L--TEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP--------------PSPPGKVTLT 17917

Query: 1368  VTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGI 1425
                + +  L  +       + ++ Y  E +    EK     +  +C  ++T  S      
Sbjct: 17918 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 17977

Query: 1426  YEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIAL------SATDLKIQSTAEGIQLYS 1479
             + V   +++GK   R+  V    K+L ++   K+        +  DLKI+    G    +
Sbjct: 17978 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN 18037

Query: 1480  FVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
                       ++W  +G  ++ + RV    T     L I E   +D GKY +
Sbjct: 18038 ----------ISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 18079



 Score =  219 bits (558), Expect = 2e-56
 Identities = 202/716 (28%), Positives = 292/716 (40%), Gaps = 101/716 (14%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTP-VKFAR 568
             P  P + + L+ ++  I I+W +P  DGGS I GY ++      D W        +K   
Sbjct: 15451 PGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATS 15510

Query: 569   FPVTGLIEGRSYIFRVRAVNKMGIGFPS----------RVSEPVAALD------------ 606
             + +TGL E + Y  R+ A+N  G+G P+          R+  P   LD            
Sbjct: 15511 YTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRAC 15570

Query: 607   ------------PA-------------EKARLKSRPSAPW----------TGQIIVTEEE 631
                         PA             +KA ++S  S             +G+ I+T E 
Sbjct: 15571 CTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVEN 15630

Query: 632   PSEGI----------VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGT 680
              S              PGPP DL V E T++ V L+W PP   G   I  Y VEK E+  
Sbjct: 15631 SSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTR 15690

Query: 681   ENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
             + +  V T     S  + +  L EG SY FRV   N  G+G P+E  E     ++   P 
Sbjct: 15691 KAYSTVATNCHKTS--WKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASER---PL 15745

Query: 741   APGKIIPSRNTDTSVVVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTC 798
              PGKI     T  SV +SWE  E      ++GY +E    GS KW  C    VK +  T 
Sbjct: 15746 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCAT--VKVTEATI 15803

Query: 799   HGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASR 858
              GL+ G+ Y FRV A N  G+S+  Q S  +  K  +       + PA        T   
Sbjct: 15804 TGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV-------IPPAFKLLFNTFTVLA 15856

Query: 859   GRVHEASPPTFQK--DALLGSKPNKPSLPSSSQNLGQTE---VSKVSETVQEELTPPPQK 913
             G   +   P   +   A+   K N P   ++  N   TE   +  + +  +E++     K
Sbjct: 15857 GEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVK 15916

Query: 914   AAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYR 973
                      + L       P  P   +   E   DS+ L W  P   GG+ I  Y V  R
Sbjct: 15917 LTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKR 15976

Query: 974   EVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE 1033
                D     W+  +   V+    K   LK    YQF++AA N    G  + ++      +
Sbjct: 15977 ---DTSTTTWQIVSA-TVARTTIKACRLKTGCEYQFRIAAENR--YGKSTYLNSEPTVAQ 16030

Query: 1034  WTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
             +   VPGPP +   +   +DS+ +QW  P+  G + V GY ++ KE  +    W  LN+ 
Sbjct: 16031 YPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNS--ILWVKLNKT 16088

Query: 1094  AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVV 1146
              I     K  GL+EGV Y FRV A N  G+GKPS ++   VA      PG  E ++
Sbjct: 16089 PIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAII 16144



 Score =  219 bits (557), Expect = 2e-56
 Identities = 204/808 (25%), Positives = 322/808 (39%), Gaps = 89/808 (11%)

Query: 439   PEIQWYRN--GVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAY 496
             PE+ W ++     L+ S  V+     + +  + +   + D G Y +           +A 
Sbjct: 11926 PEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATN-------TAG 11978

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
              FV  A   +   P    ++K ++ + D   + W  P  DGG  I  Y ++KCE     W
Sbjct: 11979 SFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW 12038

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             S  + T V      VT LIEG  YIFRVRA NK+G G P+  S+PV A    +K      
Sbjct: 12039 STYSAT-VLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTE-SKPVIAKTKYDK------ 12090

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
                                  PG P    VT+ ++  + + W PP   G + I  YF+EK
Sbjct: 12091 ---------------------PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEK 12129

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  W  VN +  +   R  + +L     Y FRV+  N  G+GEPS  +   V  D 
Sbjct: 12130 KEKHSTRWVPVN-KSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDP 12188

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIE-----ASVAGSGKWEPCN- 787
             ++ P  P        T  S+ + W +        ++GY +E     A  +    W+ CN 
Sbjct: 12189 IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNA 12248

Query: 788   NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPAL 847
                +    FT   L   Q Y FRV A N  G+   ++  EAI+ K  +     P++    
Sbjct: 12249 AAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEIL---EPPEI---- 12301

Query: 848   SDEPGGLTASRGR--VHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSET--- 902
                   L AS  +  +  A  P      L      +P+   + + +G   V +  +    
Sbjct: 12302 -----DLDASMRKLVIVRAGCPI----RLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLV 12352

Query: 903   -VQEELTPPPQKAAPQGKSKSDPLKKKTDRA---------PPSPPCDITCLESFRDSMVL 952
                  L  P       GK     +    ++A          P P  D+   +  + S  +
Sbjct: 12353 DTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHV 12412

Query: 953   GWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVA 1012
              W  P+  GG+++T Y V  RE       K        V + ++ ++NL     Y F+V 
Sbjct: 12413 SWAPPENDGGSQVTHYIVEKRE----ADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVT 12468

Query: 1013  AMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTG 1072
             A+N  G G P+ V +     +  ++ P PP  L+ +E+ K+S  L W PP+  G   + G
Sbjct: 12469 AVNEYGPGVPTDVPKPVLASD-PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12527

Query: 1073  YFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGP 1132
             Y    +E +   D+W     + +K++ L V GLKEG  Y FRV A N  GV  P +  G 
Sbjct: 12528 YITSYREEEQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGV 12585

Query: 1133  VVAETRPGTKEVVV--NVDDDGVISLNFECDKM-TPKSEFSWSKDYVSTEDSPRLEVESK 1189
               A+ +    ++++   +       L  E      P     W K       S  L V   
Sbjct: 12586 YEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKA 12645

Query: 1190  GNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
              + + +  KD+   D G YS    ++ G
Sbjct: 12646 DSSSILIIKDVTRKDSGYYSLTAENSSG 12673



 Score =  216 bits (551), Expect = 1e-55
 Identities = 206/784 (26%), Positives = 323/784 (41%), Gaps = 104/784 (13%)

Query: 475   EDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPA 534
             ED G+Y++ V      +  S  V V D        P  P D++  E  KD   ++WK+P 
Sbjct: 10977 EDGGIYSLTVENPAGSKTVSVKVLVLDK-------PGPPRDLEVSEIRKDSCYLTWKEPL 11029

Query: 535   VDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGF 594
              DGGS I  Y +++ +V +  WS  + T  K + F    L EG  Y+FRV A N+ G G 
Sbjct: 11030 DDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAENQYGRGP 11088

Query: 595   PSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYV 654
                  +P+ ALDP                              PGPP DL   +  ++ V
Sbjct: 11089 FVETPKPIKALDPLHP---------------------------PGPPKDLHHVDVDKTEV 11121

Query: 655   VLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVR 713
              L W  P + G   I  Y VE  E GT++W +  T   V +    +  L +GK+Y FRV+
Sbjct: 11122 SLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKT---VTNLECVVTGLQQGKTYRFRVK 11178

Query: 714   CSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYI 773
               N  G+G P   T + +   +  +P       PS   D  ++                I
Sbjct: 11179 AENIVGLGLPD--TTIPIECQEKLVP-------PSVELDVKLIEGLVVKAGTTVRFPAII 11229

Query: 774   EASVAGSGKWEPCNNNPVKGSRFT--------------CHGLVTGQSYIFRVRAVNAAGL 819
                   + KW    +       +T              C    TG+   +++   NAAG 
Sbjct: 11230 RGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGE---YQITVSNAAGS 11286

Query: 820   SEYSQDSEAIEVKAAIGGGVSP-DVCP---ALSDEP----GGLTASRGRVHEASPPTFQK 871
                +     ++V     G ++  DV P    +S +P    GG       V +      +K
Sbjct: 11287 KTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDT---RK 11343

Query: 872   DA--LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKT 929
             D   ++ S  +K  L       G   V +V    +  + PP           S P   K 
Sbjct: 11344 DTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLD---------STPTVAKH 11394

Query: 930   DRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVK 989
               +PPSPP      +   ++  + W  P   GG+ ITGYY+  RE    V GKW   N  
Sbjct: 11395 KFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERRE----VTGKWVRVNKT 11450

Query: 990   AVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK-CEEWTIAVPGPPHSLKCS 1048
              +++  ++++ L E   Y+F+V A N+AGL  PS  S+  K C    I  PGPP + K  
Sbjct: 11451 PIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACR--PIKPPGPPINPKLK 11508

Query: 1049  EVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRGLKE 1107
             +  +++  L W  P+  G +P+ GY V+ +  K    QW  +N +  I+    +V GL E
Sbjct: 11509 DKSRETADLVWTKPLSDGGSPILGYVVECQ--KPGTAQWNRINKDELIRQCAFRVPGLIE 11566

Query: 1108  GVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN-------FEC 1160
             G  Y FR++A N  G G+P +LA  V+A+      EV ++V    VI++           
Sbjct: 11567 GNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILAR 11626

Query: 1161  DKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
              K  P+ + +W+K+        R+++     + ++  K+    D G Y     ++ G A 
Sbjct: 11627 VKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQ 11686

Query: 1221  SYLI 1224
                I
Sbjct: 11687 GSAI 11690



 Score =  216 bits (550), Expect = 1e-55
 Identities = 215/827 (25%), Positives = 330/827 (39%), Gaps = 99/827 (11%)

Query: 417   REGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             R G TM L   V   P      P+I W +  V L     +    +     L   ++NK D
Sbjct: 13401 RAGVTMRLYVPVKGRPP-----PKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYD 13455

Query: 477   EGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVD 536
              G Y + +      ++Y+  V V D        P  P++V   E +KD   ++W+ P +D
Sbjct: 13456 AGKYILTLENSCGKKEYTIVVKVLDT-------PGPPVNVTVKEISKDSAYVTWEPPIID 13508

Query: 537   GGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPS 596
             GGSPI+ Y + K +    SWS    T      F V  L EG+SY FRV A N+ GIG P 
Sbjct: 13509 GGSPIINYVVQKRDAERKSWSTVT-TECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPG 13567

Query: 597   RVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVL 656
                + V A                                 PGP  DL V   ++S   +
Sbjct: 13568 ETRDAVKASQ------------------------------TPGPVVDLKVRSVSKSSCSI 13597

Query: 657   SWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSN 716
              WK P   G   I+ +V         WQRV   L   S +++  DL EGK Y FRV   N
Sbjct: 13598 GWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSL---SLQYSAKDLTEGKEYTFRVSAEN 13654

Query: 717   SAGVGEPSEATEVT---VVGDKLDIPKAPGKIIPSRNTDT-----------SVVVSWEES 762
               G G PSE T V    VV   LD+   P     ++               +  VSW++ 
Sbjct: 13655 ENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG 13714

Query: 763   KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEY 822
             +D        +      S +    N   +    + C     G+   + +   N AG  E 
Sbjct: 13715 EDP-------LATDTRVSVESSAVNTTLIV---YDCQKSDAGK---YTITLKNVAGTKE- 13760

Query: 823   SQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKP 882
                + +I+V    G    P     ++ E   L  +  +    S  T        S  NK 
Sbjct: 13761 --GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKW 13818

Query: 883   SLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-KSDPLKKKTDRAPPSPPCDIT 941
                +S+       V+++ E ++       +     G+  KS+P+  +     P  P    
Sbjct: 13819 VTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPN 13878

Query: 942   CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
              ++   DS+ L W  P K GG+ ITGY++ ++E    +   W+ AN   +    +K++ L
Sbjct: 13879 IVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL---WKRANKTPIRMRDFKVTGL 13935

Query: 1002  KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
              E + Y+F+V A+N+AG+G PS  SE     +  I  PG P  +    + ++S+ L W  
Sbjct: 13936 TEGLEYEFRVMAINLAGVGKPSLPSEPVVALD-PIDPPGKPEVI---NITRNSVTLIWTE 13991

Query: 1062  PVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA 1121
             P + G   +TGY V+ ++  +K   W   N   +      V  L EG  Y FR+RA N A
Sbjct: 13992 PKYDGGHKLTGYIVEKRDLPSK--SWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 14049

Query: 1122  G-VGKPSDLAGPVVAETR---------PGTKE-VVVNVDDDGVISLNFECDKMTPKSEFS 1170
             G +  PS+    ++ +           P  K+ + +   D  V++      K  PKS  S
Sbjct: 14050 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKS--S 14107

Query: 1171  WSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             WSK       S   ++ S    + +T K     D G Y+   T+  G
Sbjct: 14108 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14154



 Score =  216 bits (550), Expect = 1e-55
 Identities = 203/835 (24%), Positives = 345/835 (41%), Gaps = 98/835 (11%)

Query: 411   FDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFS 470
             FD    + GE++ +   V   P      P + W+++GV +     ++        +L   
Sbjct: 21660 FDGLIIKSGESLRIKALVQGRPV-----PRVTWFKDGVEIEKRMNMEITDVLGSTSLFVR 21714

Query: 471   HLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISW 530
                ++  G+YT+  +      +    V V+D   ++ G       ++      + + + W
Sbjct: 21715 DATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGP------IRFTNITGEKMTLWW 21768

Query: 531   KQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKM 590
               P  DG +PI  Y I+K E    +W+   D   +   +    LI G  Y FRV AVNK 
Sbjct: 21769 DAPLNDGCAPITHYIIEKRETSRLAWALIEDK-CEAQSYTAIKLINGNEYQFRVSAVNKF 21827

Query: 591   GIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEAT 650
             G+G P   S+PV A                   QI  T        VP  P     +  T
Sbjct: 21828 GVGRPLD-SDPVVA-------------------QIQYT--------VPDAPGIPEPSNIT 21859

Query: 651   RSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYC 709
              + + L+W +P    G E   Y +E+ E  +  W +V ++ P+   RF +  L EG  Y 
Sbjct: 21860 GNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYE 21919

Query: 710   FRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKE 767
             F V   N+AGVG  S  + +    + ++ P  P  +  +  + T+V + W +       E
Sbjct: 21920 FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGME 21979

Query: 768   LVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 827
             ++GY IE   A  G W   N      +R+T   L  G+ Y FRV A+N AG  +  + + 
Sbjct: 21980 IIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTG 22039

Query: 828   AIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV-----HEASP-PT---FQKDALLGSK 878
              I+   A+    +P++    + +   +  +   +     ++  P PT    + D+ L  +
Sbjct: 22040 TIK---AVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLR 22096

Query: 879   PNKPSLPSSS----QNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPP 934
              +  +  S S    +N  + +  K + TV+               SKS     K     P
Sbjct: 22097 ADIHTTDSFSTLTVENCNRNDAGKYTLTVEN-----------NSGSKSITFTVKV-LDTP 22144

Query: 935   SPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEE 994
              PP  IT  +  R S  L W  P   GGA I  Y V  RE        W+  + K  + +
Sbjct: 22145 GPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKRE---ASRRSWQVISEKC-TRQ 22200

Query: 995   AYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDS 1054
              +K+++L E + Y F+V+A+N  G+G P  + E     E     P PP  L   +  K S
Sbjct: 22201 IFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATE----QPAPPRRLDVVDTSKSS 22256

Query: 1055  LVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFR 1114
              VL W  P H G + +TGY +++++  +  D W  +     K +   V  L E   Y FR
Sbjct: 22257 AVLAWLKPDHDGGSRITGYLLEMRQKGS--DFW--VEAGHTKQLTFTVERLVEKTEYEFR 22312

Query: 1115  VRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMT---------- 1164
             V+A N AG  +P +    V+ +      ++    D  G+ +    C   +          
Sbjct: 22313 VKAKNDAGYSEPREAFSSVIIK----EPQIEPTADLTGITNQLITCKAGSPFTIDVPISG 22368

Query: 1165  -PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGI 1218
              P  + +W  + +  +++ R+ + +  ++T +T KD    D G Y   + +T G+
Sbjct: 22369 RPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGV 22423



 Score =  209 bits (533), Expect = 1e-53
 Identities = 206/802 (25%), Positives = 328/802 (40%), Gaps = 99/802 (12%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVR--MGEYYEQYSAY 496
             P I+WY++   L  +  V    + + A++     ++ + G Y +++R  MG      SA 
Sbjct: 20597 PTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMG------SAS 20650

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
               +R    +  G P  P++ K + A K  I + W+ PA DGG+ I  Y ++K E     W
Sbjct: 20651 ATIRVQILDKPGPPGGPIEFKTVTAEK--ITLLWRPPADDGGAKITHYIVEKRETSRVVW 20708

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             S  ++  ++      T +I+G  YIFRVRAVNK GIG P      VA             
Sbjct: 20709 SMVSE-HLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVA------------- 20754

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
                             +  + PGPP    VT+ T++ + + W  P   G   I  YF+EK
Sbjct: 20755 ---------------KNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEK 20799

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              +  +  W +V  E  ++  R  +  L E   Y +RV   N+AG G  SE +E     D 
Sbjct: 20800 RDKKSLGWFKVLKE-TIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADP 20858

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCN-NNPVK 792
             +D P  P KI  + +T +S+ + W +        + GY +E       +W   +    V+
Sbjct: 20859 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20918

Query: 793   GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPG 852
              + +    L  G +Y FRV AVN AG  E  + +E ++ K  +    +P++   ++    
Sbjct: 20919 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDIL---EAPEIDLDVALRTS 20975

Query: 853   GLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQ 912
              +  +   V    P         G  P   +     +NLG      +  T    L   PQ
Sbjct: 20976 VIAKAGEDVQVLIP-------FKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQ 21028

Query: 913   KAAPQ------------GKSKSDPLKKKTDRAPPSPPCD-ITCLESFRDSMVLGWKQPDK 959
                              G+ KS  +  K    P +  C  +      R ++ L W  P  
Sbjct: 21029 VTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAA--CQKLQVKHVSRGTVTLLWDPPLI 21086

Query: 960   IGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GG+ I  Y +  R   D     W   + K  S  ++K+ +L E   + F+V A N  G+
Sbjct: 21087 DGGSPIINYVIEKR---DATKRTWSVVSHKC-SSTSFKLIDLSEKTPFFFRVLAENEIGI 21142

Query: 1020  GAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
             G P   +E  K  E    VP P   L   +  K S++L W  P   G + +T Y V   E
Sbjct: 21143 GEPCETTEPVKAAE----VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---E 21195

Query: 1080  AKAKEDQ-WRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR 1138
              K K +Q W   +    K   ++V  LKE     FRV A N+ G+  P  + GP+  +  
Sbjct: 21196 RKGKGEQTWS--HAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI-GPITVKEL 21252

Query: 1139  -----------PGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVE 1187
                        PG  +V V +  +  + L +   K  PK   SW KD +  ++S  +   
Sbjct: 21253 IITPEVDLSDIPGA-QVTVRIGHNVHLELPY---KGKPKPSISWLKDGLPLKESEFVRFS 21308

Query: 1188  SKGNKTKMTFKDLGMDDLGIYS 1209
                NK  ++ K+   +  G Y+
Sbjct: 21309 KTENKITLSIKNAKKEHGGKYT 21330



 Score =  206 bits (525), Expect = 1e-52
 Identities = 199/815 (24%), Positives = 338/815 (41%), Gaps = 110/815 (13%)

Query: 438   QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
             +PE++W +    L+    ++   +     L   ++ + D G Y + +      +  +A+V
Sbjct: 18831 EPEVKWEKAEGILTDRAQIEV--TSSFTMLVIDNVTRFDSGRYNLTLENNSGSK--TAFV 18886

Query: 498   FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
              VR  D+     P+AP+++   E  KD + +SW+ P +DGG+ I  Y ++K E    +++
Sbjct: 18887 NVRVLDS-----PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18941

Query: 558   QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRP 617
                +   K   F +  L EG SY FRV A N+ GIG P+  +EPV   +P          
Sbjct: 18942 TITNNCTK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP---------- 18990

Query: 618   SAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKC 676
                                 P PP  +++ + TR+   + W+ P   G   I  Y VE  
Sbjct: 18991 --------------------PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQ 19030

Query: 677   EAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
               G+E W   +T   VK+    +  L  G+ Y FRV   N  G  +P +   V V+   +
Sbjct: 19031 TKGSEKW---STCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG-VPVIARDI 19086

Query: 737   DIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRF 796
             +I   P   +P     T  V + E+ K     +    +     +  W        + +R 
Sbjct: 19087 EIK--PSVELPFH---TFNVKAREQLK-----IDVPFKGRPQATVNWRKDGQTLKETTRV 19136

Query: 797   TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTA 856
                   T  S   +  +    G  E    + A        G ++  +   + D PG    
Sbjct: 19137 NVSSSKTVTSLSIKEASKEDVGTYELCVSNSA--------GSITVPITIIVLDRPG--PP 19186

Query: 857   SRGRVHEAS---------PPTFQKDALLGSKPNKPSLPSS------SQNLGQTEVSKVSE 901
                R+ E S         PP +     + +   +    +S      SQ + +T +  V  
Sbjct: 19187 GPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRL 19246

Query: 902   TVQEELTPPPQKAAPQGKS---KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPD 958
             T   E           GKS   +S  +  +   +PP PP     + + + +M++ W+ P 
Sbjct: 19247 TTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPV 19306

Query: 959   KIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAG 1018
               GG+ + GY++ Y+E    +   W +AN   +++   K+S L E ++Y+++V A N+AG
Sbjct: 19307 NDGGSRVIGYHLEYKERSSIL---WSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAG 19363

Query: 1019  LGAPSAVSECFKCEEWTIAVPG-----PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGY 1073
             +G         KC +    VP      PP   + + + + S+ L+W  P + G   +TGY
Sbjct: 19364 IG---------KCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGY 19414

Query: 1074  FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA-GVGKPSDLAGP 1132
              V+ +E    + +W   N   I+  Y +V  L E   Y FRV A N A  V +PS+  GP
Sbjct: 19415 IVERRELP--DGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGP 19472

Query: 1133  VVAETRPGTKEVVVNVDDDGVISLNF-ECDKMT------PKSEFSWSKDYVSTEDSPRLE 1185
             ++ +       V+++V    VI +   E  K+       P    SW+KD +  E+  R E
Sbjct: 19473 IIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTE 19532

Query: 1186  VESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
             + S  N T +T KD    D G Y   + +  G  S
Sbjct: 19533 IISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRS 19567



 Score =  206 bits (523), Expect = 2e-52
 Identities = 199/804 (24%), Positives = 355/804 (44%), Gaps = 75/804 (9%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P  +W  +G  +   +          + LT  +  + D G Y I V      +  + ++ 
Sbjct: 11235 PTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 11294

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V D    + G P  P+++  L+   +++ ISW+ P  DGGSP++ Y ++K +   D+W  
Sbjct: 11295 VLD----VPGPPTGPINI--LDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 11348

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              +    K  +  +  L +G  Y+FRVRA NK+G+G P   +  V        A+ K  P 
Sbjct: 11349 VSSGSSK-TKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTV--------AKHKFSPP 11399

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
             +P                 PG P    VT+ T +   +SW  P   G   I  Y++E+ E
Sbjct: 11400 SP-----------------PGKPV---VTDITENAATVSWTLPKSDGGSPITGYYMERRE 11439

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
               T  W RVN + P+   +F +  L EG +Y FRV   N AG+ +PS +++       + 
Sbjct: 11440 V-TGKWVRVN-KTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK 11497

Query: 738   IPKAP-GKIIPSRNTDTSVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNP-VKG 793
              P  P    +  ++ +T+ +V W +  S     ++GY +E    G+ +W   N +  ++ 
Sbjct: 11498 PPGPPINPKLKDKSRETADLV-WTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11556

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAI-GGGVSPDVC--PALSDE 850
               F   GL+ G  Y FR++A N  G  E  + +E++  K  +    V  DV     ++  
Sbjct: 11557 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVR 11616

Query: 851   PGGLTASRGRVHEASPP--TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELT 908
              G       RV     P  T+ K+  +  +  +  L    Q+L + E+ ++ E V+ +  
Sbjct: 11617 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL---IQDLPRVEL-QIKEAVRADHG 11672

Query: 909   PPPQKAA-PQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                  A    G ++   +    DR  P P  ++      +++  + W+ P   GG+EIT 
Sbjct: 11673 KYIISAKNSSGHAQGSAIVNVLDR--PGPCQNLKVTNVTKENCTISWENPLDNGGSEITN 11730

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             + V YR+     P +   + V +   +    +NL  N  Y F+V A N  G+G P+  ++
Sbjct: 11731 FIVEYRK-----PNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETK 11784

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW 1087
                     I  PG P +L  ++  K  + L+W+ P + G +P   Y V+ +  K  +D W
Sbjct: 11785 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVE-RRLKGSDD-W 11842

Query: 1088  RGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVN 1147
               +++ +IK  +  V    E   Y FRV+  N+ G    SD         +   ++ V++
Sbjct: 11843 ERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGG---ESDWVKTEEVVVKEDLQKPVLD 11899

Query: 1148  VDDDGVI------SLNFECD-KMTPKSEFSWSKDYVSTE--DSPRLEVESKGNKTKMTFK 1198
             +   GV+      ++  E   +  P  E +W+KD  +T+   SPR++++++ + +K +  
Sbjct: 11900 LKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT 11959

Query: 1199  DLGMDDLGIYSCDVTDTDGIASSY 1222
                  D G Y    T+T G   +Y
Sbjct: 11960 KAKRSDGGKYVVTATNTAGSFVAY 11983



 Score =  204 bits (519), Expect = 6e-52
 Identities = 197/777 (25%), Positives = 323/777 (41%), Gaps = 98/777 (12%)

Query: 474  KEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQP 533
            + D GLY I+V       +    V V D        P  P++    +  K  ++  W+ P
Sbjct: 8468 RPDHGLYMIKVENDHGIAKAPCTVSVLDT-------PGPPINFVFEDIRKTSVLCKWEPP 8520

Query: 534  AVDGGSPILGYFIDKCE-VGTDS-WSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMG 591
              DGGS I+ Y ++K +    DS W     T ++  ++ VT LIEG+ Y+FRVRA N+ G
Sbjct: 8521 LDDGGSEIINYTLEKKDKTKPDSEWIVVTST-LRHCKYSVTKLIEGKEYLFRVRAENRFG 8579

Query: 592  IGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATR 651
             G P  VS+P+ A DP                              P  P    V + T 
Sbjct: 8580 PG-PPCVSKPLVAKDPFGP---------------------------PDAPDKPIVEDVTS 8611

Query: 652  SYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFR 711
            + +++ W  P   G   + Y++EK E  + +W RVN  L + + +  +  L EG +Y FR
Sbjct: 8612 NSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVDGLLEGLTYVFR 8670

Query: 712  VRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTS---VVVSWEES--KDAK 766
            V   N+AG G+ S  ++     D +  P  P   IP R TDTS   + + WE        
Sbjct: 8671 VCAENAAGPGKFSPPSDPKTAHDPISPPGPP---IP-RVTDTSSTTIELEWEPPAFNGGG 8726

Query: 767  ELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDS 826
            E+VGY+++  + G+ +W  C    +K  ++T   +  G  Y  RV AVNAAG     +  
Sbjct: 8727 EIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQ 8786

Query: 827  EAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPS 886
                 +      V  DV        GG+    G+       T +  A++  +P    + +
Sbjct: 8787 PVTVAEPQEPPAVELDV-----SVKGGIQIMAGK-------TLRIPAVVTGRPVPTKVWT 8834

Query: 887  SSQ-----------NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPS 935
              +           N+G      + + ++++       A     SK    + +     P 
Sbjct: 8835 KEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV-PG 8893

Query: 936  PPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEA 995
            P  D+  + + R   +L W  P+  GG+EITG+ +  +   D     WR+     +  E 
Sbjct: 8894 PVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERK---DAKMHTWRQ----PIETER 8946

Query: 996  YK--ISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
             K  I+ L E   Y+F+V A N  G G P  +      +   +  P  P  L  +E  K 
Sbjct: 8947 SKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVD--PLGPPTSPERLTYTERTKS 9004

Query: 1054 SLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVF 1113
            ++ L WK P  +G +P+ GY ++ K    K D +  +N+         V  L E   Y F
Sbjct: 9005 TITLDWKEPRSNGGSPIQGYIIE-KRRHDKPD-FERVNKRLCPTTSFLVENLDEHQMYEF 9062

Query: 1114 RVRAINQAGVGKPSDLAGPVVAETR-PGTKEVVVNVDDDGV-----ISLNFECDKM-TPK 1166
            RV+A+N+ G  +PS     V+ +   P T ++ ++V  D +       ++   D    P 
Sbjct: 9063 RVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM 9122

Query: 1167 SEFSWSKDYVSTE------DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             +  WSK+    E         + EV     KT+++      +D G Y+   ++  G
Sbjct: 9123 PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 9179



 Score =  202 bits (515), Expect = 2e-51
 Identities = 243/1051 (23%), Positives = 411/1051 (39%), Gaps = 156/1051 (14%)

Query: 274   LHAPEFIIKP-RSHTVWEK--ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIES 330
             L  PE  +K   SHTV+ +   N+K+   I+G P P+VT  ++ VP+         I   
Sbjct: 20166 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 20225

Query: 331   RYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
                  T+ +      D  +Y  +A N  G   A+ ++VV              G  T P+
Sbjct: 20226 NL---TINLKESVTADAGRYEITAANSSGTTKAFINIVVLD----------RPGPPTGPV 20272

Query: 391   SFG-VTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVP 449
                 +T      ++E     K+D            G +V     +K              
Sbjct: 20273 VISDITEESVTLKWE---PPKYDG-----------GSQVTNYILLKR------------E 20306

Query: 450   LSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIE 507
              S + W +   +  R  +    L   +E  + I+   R G      SA V V+       
Sbjct: 20307 TSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVK-LPYTTP 20365

Query: 508   GAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFA 567
             G P+ P         ++ I + W +P  +GGS ++GY ++  +  +  W + N   ++  
Sbjct: 20366 GPPSTPW---VTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTT 20422

Query: 568   RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIV 627
              F VT +  G  Y FRV A N  G+G PS  SEPV A+D  E                  
Sbjct: 20423 HFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACE------------------ 20464

Query: 628   TEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRV 686
                         PP ++ +T+ +++ V LSW+ P   G   I  Y VE+ +     W + 
Sbjct: 20465 ------------PPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKA 20512

Query: 687   NTELPVKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKI 745
             +    V   +F +  L +   Y FRV   N+ G +  PSE     VVG    I    G +
Sbjct: 20513 SFT-NVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSE-----VVGPITCIDSYGGPV 20566

Query: 746   IPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQ 805
             I      T VV         K   G  ++     SGK  P             + LV  +
Sbjct: 20567 IDLPLEYTEVV---------KYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE 20617

Query: 806   SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEAS 865
             +    + ++        +     ++++ A+G   S  +   + D+PG      G   E  
Sbjct: 20618 NTT-DLASILIKDADRLNSGCYELKLRNAMGSA-SATIRVQILDKPG----PPGGPIEFK 20671

Query: 866   PPTFQKDALLGSKPNKPSLPS------SSQNLGQTEVSKVSETVQEELTPPPQ------- 912
               T +K  LL   P               +   +   S VSE ++E +    +       
Sbjct: 20672 TVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEY 20731

Query: 913   --------KAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
                     K       +SD +  K     P PP      +  ++SM + W +P   GG++
Sbjct: 20732 IFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSD 20791

Query: 965   ITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSA 1024
             I+GY++  R   D     W +   + + +   K++ L EN  YQ++V A+N AG G  S 
Sbjct: 20792 ISGYFLEKR---DKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSE 20848

Query: 1025  VSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE 1084
              SE +K  +  I  PGPP  ++ ++  K S+ L W  PV+ G + VTGY V++++   +E
Sbjct: 20849 PSEFYKAAD-PIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ--GEE 20905

Query: 1085  DQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKE 1143
             ++W  ++ +  ++     V  LK GV+Y FRV A+N AG G+P ++  PV A+      E
Sbjct: 20906 EEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE 20965

Query: 1144  ----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKT 1193
                       V+    +D  + + F   K  P    +W KD  +     R  +E+  + +
Sbjct: 20966 IDLDVALRTSVIAKAGEDVQVLIPF---KGRPPPTVTWRKDEKNLGSDARYSIENTDSSS 21022

Query: 1194  KMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVE 1253
              +T   +  +D G Y   + +  G   S  +  + L             T     +L V+
Sbjct: 21023 LLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVL------------DTPAACQKLQVK 21070

Query: 1254  ILEKGQVRFWMQAEKLSGNAK-VNYIFNEKE 1283
              + +G V        + G +  +NY+  +++
Sbjct: 21071 HVSRGTVTLLWDPPLIDGGSPIINYVIEKRD 21101



 Score =  202 bits (513), Expect = 3e-51
 Identities = 201/738 (27%), Positives = 302/738 (40%), Gaps = 66/738 (8%)

Query: 438   QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
             +P I W ++G+PL  S++V+   +  + TL+  +  KE  G YT+ +            V
Sbjct: 21287 KPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21346

Query: 498   FVRDADAEIEGAPAAPLD-VKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
                       G P+ P   ++  E   D +I+SW  P  +GG  I  Y I+K E    +W
Sbjct: 21347 ITL-------GPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 21399

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
                  +  +   F V  L++   Y FRVRA N+ G+                        
Sbjct: 21400 KMVCSSVAR-TTFKVPNLVKDAEYQFRVRAENRYGV------------------------ 21434

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYF-VEK 675
              S P    IIV + +     +PGPP    +   T   + L+W  P   G   +  F VEK
Sbjct: 21435 -SQPLVSSIIVAKHQFR---IPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEK 21490

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  WQ+VNT  P+    +    L EG  Y FRV   NSAG+  PS+ ++ T+    
Sbjct: 21491 KERNSILWQKVNTS-PISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSP 21549

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKG 793
             +D P  P  I  +R T   + + W         ++VGY IE    G+ +W  CN   V  
Sbjct: 21550 VDPPGTPDYIDVTRET---ITLKWNPPLRDGGSKIVGYSIEKR-QGNERWVRCNFTDVSE 21605

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAIGGGV---SPDVCPALSD 849
              ++T  GL  G  Y FR+ A NA G +S  SQ S  I  +      +    P+    L  
Sbjct: 21606 CQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLII 21665

Query: 850   EPGGLTASRGRVHEASPP--TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEEL 907
             + G     +  V     P  T+ KD   G +  K      +  LG T +     T     
Sbjct: 21666 KSGESLRIKALVQGRPVPRVTWFKD---GVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21722

Query: 908   TPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                 +     G +K++ +K K    P      I       + M L W  P   G A IT 
Sbjct: 21723 VYTVEAKNASGSAKAE-IKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITH 21781

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             Y +  RE    +     E   +A S  A K+ N  E   YQF+V+A+N  G+G P     
Sbjct: 21782 YIIEKRET-SRLAWALIEDKCEAQSYTAIKLINGNE---YQFRVSAVNKFGVGRPLDSDP 21837

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW 1087
                  ++T  VP  P   + S +  +S+ L W  P   G + +  Y ++ +E K+   +W
Sbjct: 21838 VVAQIQYT--VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS--TRW 21893

Query: 1088  -RGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE--TRPGTKEV 1144
              + +++  I     KV GL EG  Y F V A N AGVG  S ++  +       P     
Sbjct: 21894 VKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPT 21953

Query: 1145  VVNVDDDGVISLNFECDK 1162
             VV V D    +++ E  K
Sbjct: 21954 VVKVTDTSKTTVSLEWSK 21971



 Score =  201 bits (510), Expect = 6e-51
 Identities = 194/718 (27%), Positives = 295/718 (41%), Gaps = 94/718 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P++ W    + L  +  V    + +R TLT     + D G Y + +      + +S  V 
Sbjct: 22372 PKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVV 22431

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V      + G    P++V  + A     ++SW +P   GG+ I  Y ++K E GT +W  
Sbjct: 22432 VIGRPGPVTG----PIEVSSVSAES--CVLSWGEPKDGGGTEITNYIVEKRESGTTAWQL 22485

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              N + VK  +  VT L +   Y FRV + N+ G+  P   S P+ A  P           
Sbjct: 22486 VNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE-SAPIIAEHPF---------- 22533

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                              + P  PT   V   + + + + W+ P   G   I+ Y+VEK E
Sbjct: 22534 -----------------VPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKE 22576

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
               T  W + N ++P     + +  L EG  Y FR    N+AGV + SEA+   +  + +D
Sbjct: 22577 RNTILWVKEN-KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVD 22635

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIE---ASVAGSGKWEPCNNNPVKGS 794
              P  P     +R+T  S++ S        ++VGY IE    S  G G+W  CN   V  +
Sbjct: 22636 APGRPEVTDVTRST-VSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDN 22694

Query: 795   RFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG 853
              FT   L  G +Y FRV A NAAG +S+ S+ +  +  +         +  P  ++    
Sbjct: 22695 FFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR--------DEYAPPKAELDAR 22746

Query: 854   LTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQK 913
             L      +   S      DA +G KP     P      G  E+  + E V  + T     
Sbjct: 22747 LHGDLVTIRAGSDLVL--DAAVGGKPE----PKIIWTKGDKELD-LCEKVSLQYTGKRAT 22799

Query: 914   AAPQGKSKSDPLK------------------KKTDRAPPSPPCDITCLESFRDSMVLGWK 955
             A  +   +SD  K                  K  D   P P   +T     ++   L W 
Sbjct: 22800 AVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLD--SPGPCGKLTVSRVTQEKCTLAWS 22857

Query: 956   QPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEE----AYKISNLKENMVYQFQV 1011
              P + GGAEIT Y V  RE            N   V  E    +Y ++ L +N  Y F+V
Sbjct: 22858 LPQEDGGAEITHYIVERRET--------SRLNWVIVEGECPTLSYVVTRLIKNNEYIFRV 22909

Query: 1012  AAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVT 1071
              A+N  G G P           +TI  P PP   +     K+ +++QW  P   G   ++
Sbjct: 22910 RAVNKYGPGVPVESEPIVARNSFTI--PSPPGIPEEVGTGKEHIIIQWTKPESDGGNEIS 22967

Query: 1072  GYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              Y VD +E K+   +W  +N +  + +  LKV  L EG  Y FRV A+N AG  +PS+
Sbjct: 22968 NYLVDKREKKSL--RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 23023



 Score =  191 bits (486), Expect = 4e-48
 Identities = 191/741 (25%), Positives = 302/741 (40%), Gaps = 88/741 (11%)

Query: 412   DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH 471
             DV   R G+T+ +  RV   PE     P+I W + G  L   K V  +    R  L    
Sbjct: 11611 DVITVRVGQTIRILARVKGRPE-----PDITWTKEGKVLVREKRVDLIQDLPRVELQIKE 11665

Query: 472   LNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWK 531
               + D G Y I  +    + Q SA V V D        P    ++K     K+   ISW+
Sbjct: 11666 AVRADHGKYIISAKNSSGHAQGSAIVNVLDR-------PGPCQNLKVTNVTKENCTISWE 11718

Query: 532   QPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMG 591
              P  +GGS I  + ++  +     WS       K  R     L+    Y FRV A NK+G
Sbjct: 11719 NPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTK--RLIKANLLANNEYYFRVCAENKVG 11776

Query: 592   IGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATR 651
             +G       P+ A++P ++                           PG P +L + +  +
Sbjct: 11777 VGPTIETKTPILAINPIDR---------------------------PGEPENLHIADKGK 11809

Query: 652   SYVVLSWKPPG-QRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCF 710
             ++V L W+ P    G   + Y VE+   G+++W+RV+ +  +K   + +    E + Y F
Sbjct: 11810 TFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVH-KGSIKETHYMVDRCVENQIYEF 11868

Query: 711   RVRCSNSAGVGEPSEATEVTVVGD----KLDIPKAPGKIIPSRNT---DTSV------VV 757
             RV+  N  G  +  +  EV V  D     LD+  +    + + +T   +  V       V
Sbjct: 11869 RVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEV 11928

Query: 758   SWEESKDAKELV---GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             +W + KDA +L       I+   A S K+         G ++      T  S++     V
Sbjct: 11929 AWTKDKDATDLTRSPRVKIDTR-ADSSKFSLTKAKRSDGGKYVVTATNTAGSFV-AYATV 11986

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEP--GGLTASRGRVHEASPPTFQKD 872
             N        ++ + ++        VS D C    D P   G    +  + E         
Sbjct: 11987 NVLDKPGPVRNLKIVD--------VSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW 12038

Query: 873   ALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRA 932
             +   +    P    +    G   + +V    +    PP +      K+K D    K  R 
Sbjct: 12039 STYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYD----KPGR- 12093

Query: 933   PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVS 992
              P PP ++T +   ++ M + W  P+  GG  ITGY++  +E       +W   N  A+ 
Sbjct: 12094 -PDPP-EVTKVS--KEEMTVVWNPPEYDGGKSITGYFLEKKEKHS---TRWVPVNKSAIP 12146

Query: 993   EEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRK 1052
             E   K+ NL  +  YQF+V A N  G+G PS  S     ++  I  PGPP + +  +  K
Sbjct: 12147 ERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKD-PIEPPGPPTNFRVVDTTK 12205

Query: 1053  DSLVLQWKPPVHSGRTPVTGYFVDL--KEAKAKEDQ-WRGLNEAA-IKNVYLKVRGLKEG 1108
              S+ L W  PV+ G  P+ GY V++  K A A  D+ W+  N AA +      V  L E 
Sbjct: 12206 HSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDEN 12265

Query: 1109  VSYVFRVRAINQAGVGKPSDL 1129
               Y FRV A NQ G+G+P++L
Sbjct: 12266 QEYEFRVCAQNQVGIGRPAEL 12286



 Score =  191 bits (484), Expect = 7e-48
 Identities = 185/740 (25%), Positives = 303/740 (40%), Gaps = 88/740 (11%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P+ P +V  L+  K  + +SW +P  DGGS + GY+I++ E  TD W + N T +    +
Sbjct: 24027 PSNPPEV--LDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMY 24084

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGL+    Y FR+ A N +G+   S  SEPV   DP +K                   
Sbjct: 24085 TVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDK------------------- 24125

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNT 688
                     P  P +L +   ++  V L W KP    G E + Y+VE  ++G   W++ N 
Sbjct: 24126 --------PSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNK 24177

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPS 748
             E  +K  +F +  L E   Y FRV   N  G+  P        +  KL   +APG     
Sbjct: 24178 ER-IKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTKLTSGEAPGIRKEM 24234

Query: 749   RNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYI 808
             ++  T +    E ++ + ++VG  +        KW       ++  ++       G+++ 
Sbjct: 24235 KDVTTKL---GEAAQLSCQIVGRPLPDI-----KWYRFGKELIQSRKYKMSS--DGRTHT 24284

Query: 809   FRVRAVNAAGLSEYS----QDSEAIEVKAAIGGGVSPDVCPA--LSDEPGGLTASRGRVH 862
               V          Y+     +   +E  + +    +P   P   L ++  G   S  R+H
Sbjct: 24285 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLH 24344

Query: 863   EA--SPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS 920
                   P        G K     L  +S+N+        +  V + +    Q+    GK 
Sbjct: 24345 VMYIGRPVPAMTWFHGQK-----LLQNSENITIENTEHYTHLVMKNV----QRKTHAGKY 24395

Query: 921   KSDP----------LKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYV 970
             K             L  +    P  P   I      ++S V+ WK P   GG+ IT Y V
Sbjct: 24396 KVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVV 24455

Query: 971   NYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK 1030
                E  +G   +W+  +  A+S    +I NL EN  Y F+V+A N  G+  P  VS    
Sbjct: 24456 EKCEAKEGA--EWQLVS-SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVI 24512

Query: 1031  CEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGL 1090
              +      PG P     + V KDS V+ WKPP   G   +  Y+++ +E   K+++W  +
Sbjct: 24513 IKS-PFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKRE--KKQNKWISV 24569

Query: 1091  NEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET-----RPGTKEVV 1145
                 I+     V+ L EG+ Y FRV+  N  G  + S+++ P+  ++      P  KE +
Sbjct: 24570 TTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEEL 24629

Query: 1146  VNVDDDGVISLNFECDKMT--PKSEFSW---SKDYVSTEDSPRLEVESKGNKTKMTFKDL 1200
              N++     +    C K+T  PK    W    K+ ++     R++ E KG   ++    +
Sbjct: 24630 RNLNVRYQSNATLVC-KVTGHPKPIVKWYRQGKEIIADGLKYRIQ-EFKGGYHQLIIASV 24687

Query: 1201  GMDDLGIYSCDVTDTDGIAS 1220
               DD  +Y    T+  G  S
Sbjct: 24688 TDDDATVYQVRATNQGGSVS 24707



 Score =  189 bits (481), Expect = 1e-47
 Identities = 201/817 (24%), Positives = 331/817 (40%), Gaps = 114/817 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             PEI W R     +    VQ         L+  + ++ D G Y +++      +  SA+V 
Sbjct: 17749 PEITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSK--SAFVT 17804

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V+  D      P  P ++   E  KD   + W+ P +DGG+ +  Y IDK E    +++ 
Sbjct: 17805 VKVLDT-----PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYAN 17859

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              +    K + F V  L EG  Y FRV A N+ G+G P    + V A +P           
Sbjct: 17860 VSSKCSKTS-FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP----------- 17907

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                                P PP  +++T+ +++   L W+ P   G   ++ Y VE   
Sbjct: 17908 -------------------PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 17948

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
              GTE W  V      K     +  L+ G+ Y FRV+  N  G  +P     V V+   L 
Sbjct: 17949 KGTEKWSIVAES---KVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP-RVLGVPVIAKDLT 18004

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGK----WEPCNNNPVKG 793
             I   P   +P          S +  +D K      IE  V G  +    W   +  P+K 
Sbjct: 18005 IQ--PSLKLPFNT------YSIQAGEDLK------IEIPVIGRPRPNISWVK-DGEPLKQ 18049

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG 853
             +    +   T  S +  ++  N     +Y+       V A    G + +    +  E  G
Sbjct: 18050 TT-RVNVEETATSTVLHIKEGNKDDFGKYT-------VTATNSAGTATENLSVIVLEKPG 18101

Query: 854   LTASRGRVHEAS---------PPTFQKDALLGSK-PNKPSLPSSSQNLGQTEVSKVSETV 903
                   R  E S         PP +     + +    K    +++ ++    V++ +  +
Sbjct: 18102 PPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKI 18161

Query: 904   QEELTPPPQKA---APQGKSKSDPLKKKT-----DRAPPSPPCDITCLESFRDSMVLGWK 955
              +  T    +    A     KS PL  K          P PP         +D M++ W 
Sbjct: 18162 TKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWH 18221

Query: 956   QPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMN 1015
             +P   GG +I GY++  +E    +   W + N   + +  +K + L E + Y+F+V+A N
Sbjct: 18222 EPVNDGGTKIIGYHLEQKEKNSIL---WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAEN 18278

Query: 1016  MAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFV 1075
             + G+G PS VSECF   +     PG P ++    + ++++ L+WK P + G + +TGY V
Sbjct: 18279 IVGIGKPSKVSECFVARD-PCDPPGRPEAI---VITRNNVTLKWKKPAYDGGSKITGYIV 18334

Query: 1076  DLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAG-VGKPSDLAGPVV 1134
             + K+    + +W   +   +      V GL E   Y FRV A N AG   +PSD +G + 
Sbjct: 18335 EKKD--LPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAIT 18392

Query: 1135  AETR---------PGTKEV-VVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTED-SPR 1183
             A            P  K+V VV+  +  V+  +    +  P  +  WSKD    E+ + R
Sbjct: 18393 ARDEIDAPNASLDPKYKDVIVVHAGETFVLEADI---RGKPIPDVVWSKDGKELEETAAR 18449

Query: 1184  LEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
             +E++S   KT +  KD    D G Y   +++  G  S
Sbjct: 18450 MEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18486



 Score =  188 bits (477), Expect = 4e-47
 Identities = 155/528 (29%), Positives = 237/528 (44%), Gaps = 49/528 (9%)

Query: 638   PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
             P PP +L VTE T+  V ++W+PP   G   I  Y VEK EA  +++  V T     S  
Sbjct: 16729 PSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNS-- 16786

Query: 697   FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
             + +  L EG SY FRV   N  G+G P++  +   V +   +P+ PGKI     T  SV 
Sbjct: 16787 WKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE---VPQPPGKITVDDVTRNSVS 16843

Query: 757   VSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             +SW   E     +++ Y +E     S KW  C    VK  +     L  G+ Y+FRV AV
Sbjct: 16844 LSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEYLFRVVAV 16901

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDAL 874
             N  G S+    +  I  K  +   + PDV PA S      +   G+  +   P       
Sbjct: 16902 NEKGRSDPRSLAVPIVAKDLV---IEPDVKPAFSS----YSVQVGQDLKIEVP------- 16947

Query: 875   LGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-------------K 921
             +  +P KP++  +   L   + ++++ T   +LT    K   +                K
Sbjct: 16948 ISGRP-KPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQK 17006

Query: 922   SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPG 981
             +  ++  T   P  P   +   +   +S+ L W  P   GG +IT Y V  R+    V  
Sbjct: 17007 TASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTV-- 17064

Query: 982   KWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGP 1041
              W   +   V+    K++ LK    YQF++ A N    G   A+       ++    PGP
Sbjct: 17065 -WDVVSA-TVARTTLKVTKLKTGTEYQFRIFAENR--YGQSFALESDPIVAQYPYKEPGP 17120

Query: 1042  PHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLK 1101
             P +   + + KDS+V+QW  PV++G +PV GY ++ KE  +    W  +N+  I +   K
Sbjct: 17121 PGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNS--ILWTKVNKTIIHDTQFK 17178

Query: 1102  VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVV 1146
              + L+EG+ Y FRV A N  GVGK S  +   VA      PGT E ++
Sbjct: 17179 AQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIM 17226



 Score =  179 bits (455), Expect = 2e-44
 Identities = 211/823 (25%), Positives = 315/823 (38%), Gaps = 119/823 (14%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRV--RMGEYYEQYSAY 496
             P++ W + G+     K    L     A L   +  ++D G Y++ +    GE     + +
Sbjct: 12331 PKVTWRKVGIDNVVRKGQVDLVD-TMAFLVIPNSTRDDSGKYSLTLVNPAGEK----AVF 12385

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             V VR  D      P    D+K  +  K    +SW  P  DGGS +  Y ++K E    +W
Sbjct: 12386 VNVRVLDT-----PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW 12440

Query: 557   SQCNDTP-VKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKS 615
             S    TP VK   F VT L+ G  Y FRV AVN+ G G P+ V +PV A DP  +     
Sbjct: 12441 STV--TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE----- 12493

Query: 616   RPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEK 675
                                   P PP  L VTE T++   L+W PP + G   I  ++  
Sbjct: 12494 ----------------------PDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITS 12531

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
                  +   R      VK     +  L EGK Y FRV   N+ GV  P EA  V    ++
Sbjct: 12532 YREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQ 12591

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSG----KWEPCNNNPV 791
             L  PK    ++P + T           K  K+L    IEA V G      KW+   +  V
Sbjct: 12592 LLPPKI---LMPEQIT----------IKAGKKL---RIEAHVYGKPHPTCKWKKGEDEVV 12635

Query: 792   KGSRFTCHGLVTGQSYIFRVRAVNAAGL----SEYSQDSEAIEVKAAIGGGVSPDVCPA- 846
               S    H   +    I +      +G     +E S  ++  ++K  +     P   P  
Sbjct: 12636 TSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFD 12695

Query: 847   LSD--------------EPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLG 892
             +SD              E GG   +   V +           L S   K S        G
Sbjct: 12696 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASV-TKTSCRVGKLIPG 12754

Query: 893   QTEVSKVSET----VQEELTPPPQKAA-PQGKSKSDPLKKKTDRAPPSPPCDITCLESFR 947
             Q  + +V       + E LT P   A  P G               PS P +    +  +
Sbjct: 12755 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGV--------------PSEPKNARVTKVNK 12800

Query: 948   DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY 1007
             D + + W +PD  GG+ I GY +  +E    +   W +AN   V    Y  + L E + Y
Sbjct: 12801 DCIFVAWDRPDSDGGSPIIGYLIERKERNSLL---WVKANDTLVRSTEYPCAGLVEGLEY 12857

Query: 1008  QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 1067
              F++ A+N AG   PS  +E +      +  PG P  +   +V K ++ L W  P H G 
Sbjct: 12858 SFRIYALNKAGSSPPSKPTE-YVTARMPVDPPGKPEVI---DVTKSTVSLIWARPKHDGG 12913

Query: 1068  TPVTGYFVDLKEAKAKEDQWRGLNEAA--IKNVYLKVRGLKEGVSYVFRVRAINQAGVGK 1125
             + + GYFV+    K   D+W   N A   I        GL+E   Y FR  A     +  
Sbjct: 12914 SKIIGYFVEA--CKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISP 12971

Query: 1126  PSDLAGPV--VAETRPGTKEVVVNVDDDGVISLNFE-CDKMT----PKSEFSWSKDYVST 1178
             PS+ + PV  +AE  P   ++ V +     +      C   T    P    SW KD    
Sbjct: 12972 PSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLL 13031

Query: 1179  EDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
             + +  +++  + N   +    +   D G Y+    ++ G  S+
Sbjct: 13032 KPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSA 13074



 Score =  177 bits (450), Expect = 6e-44
 Identities = 186/778 (23%), Positives = 306/778 (39%), Gaps = 86/778 (11%)

Query: 465   ATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKD 524
             +TLT  + N+ D G YT+ V      +  +  V V D        P  P+  K  +  + 
Sbjct: 22106 STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPG-----PPGPITFK--DVTRG 22158

Query: 525   YIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRV 584
                + W  P +DGG+ I  Y ++K E    SW   ++   +   F V  L EG  Y FRV
Sbjct: 22159 SATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQI-FKVNDLAEGVPYYFRV 22217

Query: 585   RAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDL 644
              AVN+ G+G P  + EP+ A                       TE+       P PP  L
Sbjct: 22218 SAVNEYGVGEPYEMPEPIVA-----------------------TEQ-------PAPPRRL 22247

Query: 645   SVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLA 703
              V + ++S  VL+W  P   G   I  Y +E  + G++ W         K   F +  L 
Sbjct: 22248 DVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH---TKQLTFTVERLV 22304

Query: 704   EGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK-----LDIPKAPGKIIPSRNTDTSVVVS 758
             E   Y FRV+  N AG  EP EA    ++ +       D+     ++I  +      +  
Sbjct: 22305 EKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDV 22364

Query: 759   WEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAG 818
                 + A ++     E  +  + +           +  T    + G S  + +   N AG
Sbjct: 22365 PISGRPAPKVTWKLEEMRLKETDRVSITTTKD--RTTLTVKDSMRGDSGRYFLTLENTAG 22422

Query: 819   LSEYSQDSEAIEVKAAIGG-----GVSPDVCPALSDEP--GGLTASRGRVHEASPPTFQK 871
             +  +S     I     + G      VS + C     EP  GG T     + E        
Sbjct: 22423 VKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRE----- 22477

Query: 872   DALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-KSDPLKKKTD 930
                  S      L +SS    Q +V+ +++ ++       +      K  +S P+  +  
Sbjct: 22478 -----SGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHP 22532

Query: 931   RAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKA 990
               PPS P          ++M + W++P   GG++I GY+V  +E    +   W + N   
Sbjct: 22533 FVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTIL---WVKENKVP 22589

Query: 991   VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEV 1050
               E  YK++ L E + YQF+  A+N AG+   S  S     +   +  PG P   + ++V
Sbjct: 22590 CLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQN-PVDAPGRP---EVTDV 22645

Query: 1051  RKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKED-QWRGLNEAAIKNVYLKVRGLKEGV 1109
              + ++ L W  P + G + V GY ++ K      D +W   N   + + +  V  L EG 
Sbjct: 22646 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22705

Query: 1110  SYVFRVRAINQAGV-GKPSDLAGPVVA--ETRPGTKEVVVNVDDDGVISLNFECDKM--- 1163
             +Y FRV A N AGV  K S+  GPV    E  P   E+   +  D ++++    D +   
Sbjct: 22706 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD-LVTIRAGSDLVLDA 22764

Query: 1164  ----TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
                  P+ +  W+K     +   ++ ++  G +     K     D G Y+  V +  G
Sbjct: 22765 AVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22822



 Score =  167 bits (422), Expect = 1e-40
 Identities = 156/528 (29%), Positives = 237/528 (44%), Gaps = 54/528 (10%)

Query: 637  VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFV-EKCEAGTENWQRVNTELPVKSP 695
            VPGP  DL      R   +L+W  P   G   I  F+ E+ +A    W++     P+++ 
Sbjct: 8891 VPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ-----PIETE 8945

Query: 696  RFA--LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDT 753
            R    +  L EG+ Y FRV   N  G G P E   +  V D L  P +P ++  +  T +
Sbjct: 8946 RSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAV-DPLGPPTSPERLTYTERTKS 9004

Query: 754  SVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRV 811
            ++ + W+E  S     + GY IE        +E  N      + F    L   Q Y FRV
Sbjct: 9005 TITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRV 9064

Query: 812  RAVNAAGLSEYS-------QDSEA---IEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV 861
            +AVN  G SE S       QD E    I+++ ++ G    D     + EP  + A    V
Sbjct: 9065 KAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG----DTIKVKAGEPVHIPAD---V 9117

Query: 862  HEASPPTFQ--KDALLGSKPNKP---SLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAP 916
                 P  +  K+  +  KP      +    S++  +TE+S      +++ T     +  
Sbjct: 9118 TGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNR 9177

Query: 917  QGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVI 976
             G    +   +  DR  PSPP ++   +   +S  L W  P   GG+EIT Y ++ R+  
Sbjct: 9178 LGSVFRNVHVEVYDR--PSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDA- 9234

Query: 977  DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
                 +W E    AV E+ Y I  L  N  Y+F+V A+N  G+       EC K ++  I
Sbjct: 9235 SRKKAEWEEVTNTAV-EKRYGIWKLIPNGQYEFRVRAVNKYGIS-----DEC-KSDKVVI 9287

Query: 1037 A----VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNE 1092
                 +PGPP   K     K S+++ W PP+ +G +P+TGY+++ +E  +    W  ++ 
Sbjct: 9288 QDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSP--YWSRVSR 9345

Query: 1093 AAIKNVYLK-----VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA 1135
            A I  V LK     V  L EGV Y FR  AIN AG+G PS+ + P VA
Sbjct: 9346 APITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVA 9393



 Score =  157 bits (397), Expect = 8e-38
 Identities = 201/762 (26%), Positives = 300/762 (39%), Gaps = 125/762 (16%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESR-YGM------HTLEINGCDF 344
             E  +L C I G P P + WY+           GK +I+SR Y M      HTL +   + 
Sbjct: 24243 EAAQLSCQIVGRPLPDIKWYRF----------GKELIQSRKYKMSSDGRTHTLTVMTEEQ 24292

Query: 345   EDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFE 404
             ED   Y   A N  GE+   + ++++         +FH G    PL              
Sbjct: 24293 EDEGVYTCIATNEVGEVETSSKLLLQA------TPQFHPG---YPLK------------- 24330

Query: 405   IHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGER 464
                 +K+   +G  G T+ L    +  P      P + W+     L  S+ + T+ + E 
Sbjct: 24331 ----EKY---YGAVGSTLRLHVMYIGRPV-----PAMTWFHGQKLLQNSENI-TIENTEH 24377

Query: 465   AT-LTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDA--DAEIEGAPAAPLDVKCLEA 521
              T L   ++ +        +   G+Y  Q S      DA  D EI+  P  P     +EA
Sbjct: 24378 YTHLVMKNVQR--------KTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEA 24429

Query: 522   N-KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSY 580
               K+  +ISWK PA DGGS I  Y ++KCE    +  Q   + +      +  L E   Y
Sbjct: 24430 LLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGY 24489

Query: 581   IFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGP 640
              FRV A N  GI  P  VS  V    P EK                           PG 
Sbjct: 24490 YFRVSAQNTFGISDPLEVSSVVIIKSPFEK---------------------------PGA 24522

Query: 641   PTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFAL 699
             P   ++T  T+   V++WKPP   G   I  Y++EK E     W  V TE  ++   F++
Sbjct: 24523 PGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTE-EIRETVFSV 24581

Query: 700   FDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP-KAPGKIIPSRNTD----TS 754
              +L EG  Y FRV+C N  G  E SE +E   +  K D+P +AP      RN +    ++
Sbjct: 24582 KNLIEGLEYEFRVKCENLGGESEWSEISE--PITPKSDVPIQAPHFKEELRNLNVRYQSN 24639

Query: 755   VVVSWEESKDAKELVGYYIEAS--VAGSGKWEPCNNNPVKGS--RFTCHGLVTGQSYIFR 810
               +  + +   K +V +Y +    +A   K+        KG   +     +    + +++
Sbjct: 24640 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKY---RIQEFKGGYHQLIIASVTDDDATVYQ 24696

Query: 811   VRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQ 870
             VRA N  G S     S  +EV A I         P   +  G + A RG V     P   
Sbjct: 24697 VRATNQGG-SVSGTASLEVEVPAKIH-------LPKTLEGMGAVHALRGEVVSIKIPFSG 24748

Query: 871   K-DALLGSKPNKPSLPSSSQN---LGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLK 926
             K D ++  +  +  + ++      + ++  S V     E           + +   D   
Sbjct: 24749 KPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKT 24808

Query: 927   KKTDRAP-PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWRE 985
              + D A  P PP  +   +  RDS+ L W +P   GG++IT Y V   E       +W  
Sbjct: 24809 VELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV---EKCATTAERW-- 24863

Query: 986   ANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
               V    E  Y + NL     YQF+V A N  GL  PS  SE
Sbjct: 24864 LRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSE 24905



 Score =  153 bits (387), Expect = 1e-36
 Identities = 143/539 (26%), Positives = 230/539 (42%), Gaps = 61/539 (11%)

Query: 637  VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFV-EKCEAGTENWQRVNTELPVKSP 695
            +PGP  D+  ++ T+S   L+W+PP   G   I+++V E+ EAG        T +PV S 
Sbjct: 8174 LPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRR------TYIPVMSG 8227

Query: 696  R----FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNT 751
                 + + DL     Y FRV+  N  G GE  E     +  D    P  P  +     T
Sbjct: 8228 ENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPT 8287

Query: 752  DTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIF 809
              ++ ++W+        +++GY IE    G  +W+ CN + V    +T  GL  G+ Y F
Sbjct: 8288 AEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQF 8347

Query: 810  RVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVC--PALSDEPGGLTASRGRVHEASPP 867
            RVRA NAAG+SE    S A     A+    +P V    +L  + G   A    +  +  P
Sbjct: 8348 RVRAENAAGISE---PSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYP 8404

Query: 868  TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEE---LTPPPQKAAPQGKSKSDP 924
            T     +   K     +P   +      V +    VQEE   + P  Q+ +     K + 
Sbjct: 8405 T-----ITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 8459

Query: 925  ----------------LKKKTDRAPPSPPCDITCLES--------FRD----SMVLGWKQ 956
                            +K + D      PC ++ L++        F D    S++  W+ 
Sbjct: 8460 QLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEP 8519

Query: 957  PDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNM 1016
            P   GG+EI  Y +  ++     P          +    Y ++ L E   Y F+V A N 
Sbjct: 8520 PLDDGGSEIINYTLEKKDKTK--PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8577

Query: 1017 AGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVD 1076
             G G P  VS+    ++     P  P      +V  +S++++W  P  +G +P+ GY+++
Sbjct: 8578 FGPG-PPCVSKPLVAKD-PFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNG-SPILGYWLE 8634

Query: 1077 LKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA 1135
             +E  +    W  +N++ +  +   V GL EG++YVFRV A N AG GK S  + P  A
Sbjct: 8635 KREVNS--THWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTA 8691



 Score =  153 bits (386), Expect = 2e-36
 Identities = 113/372 (30%), Positives = 180/372 (48%), Gaps = 30/372 (8%)

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
             +S P+       PP PP         +DSMV+ W +P   GG EI GY +  R+  +GV 
Sbjct: 18584 ESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDK-EGV- 18641

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
              +W + N K +++   +++ L E   Y+F+VAA N AG+G PS  S  ++  +  +  PG
Sbjct: 18642 -RWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD-ALYPPG 18699

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVY 1099
             PP + K ++  + S+ L W  P++ G  PV GY V++KEA A  D+W        ++   
Sbjct: 18700 PPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAA--DEWTTCTPPTGLQGKQ 18757

Query: 1100  LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN-- 1157
               V  LKE   Y FR+ AIN  GVG+P+ L G VVA+ R    E+ ++ D   V+ L   
Sbjct: 18758 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18817

Query: 1158  -----FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
                  F   K  P+ E  W K      D  ++EV S  + T +   ++   D G Y+  +
Sbjct: 18818 ATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLVIDNVTRFDSGRYNLTL 18875

Query: 1213  TDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGN 1272
              +  G  ++++       R+L        P+ PV   L +  ++K  V    +   + G 
Sbjct: 18876 ENNSGSKTAFV-----NVRVL------DSPSAPV--NLTIREVKKDSVTLSWEPPLIDGG 18922

Query: 1273  AKV-NYIFNEKE 1283
             AK+ NYI  ++E
Sbjct: 18923 AKITNYIVEKRE 18934



 Score =  152 bits (385), Expect = 2e-36
 Identities = 165/617 (26%), Positives = 249/617 (40%), Gaps = 104/617 (16%)

Query: 478  GLYTIRVRMGEYY----EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQP 533
            G Y  RVR    Y    E  S  V ++D    + G P  P   K L   K  +++SW  P
Sbjct: 9262 GQYEFRVRAVNKYGISDECKSDKVVIQDP-YRLPGPPGKP---KVLARTKGSMLVSWTPP 9317

Query: 534  AVDGGSPILGYFIDKCEVGTDSWSQCNDTPV-----KFARFPVTGLIEGRSYIFRVRAVN 588
              +GGSPI GY+++K E G+  WS+ +  P+     K   F V  L+EG  Y FR  A+N
Sbjct: 9318 LDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 9377

Query: 589  KMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTE 648
              GIG PS  S+P  A DP                              PGPP+   V +
Sbjct: 9378 AAGIGPPSEPSDPEVAGDPI---------------------------FPPGPPSCPEVKD 9410

Query: 649  ATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT-ELPVKSPRFALFDLAEGK 706
             T+S + L WKPP + G   I  Y VE  E GT +W+RVN  +  + +    + +L E +
Sbjct: 9411 KTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELR 9470

Query: 707  SYCFRVRCSNSAGVGEPSEATE-----------------------VTVVGDKLDIPKAPG 743
             Y FRV+  N AG  EPS+ T                        V   G ++ IP    
Sbjct: 9471 KYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPA--- 9527

Query: 744  KIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVT 803
             +I  R T  S   SWE    AK+ +   +   +    + E   N+ V      C    T
Sbjct: 9528 -VIKGRPTPKS---SWEFDGKAKKAMKDGVH-DIPEDAQLETAENSSVIIIP-ECKRSHT 9581

Query: 804  GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHE 863
            G+   + + A N AG     Q +    VK     G   D+   +SD    +T    R+  
Sbjct: 9582 GK---YSITAKNKAG-----QKTANCRVKVMDVPGPPKDL--KVSD----ITRGSCRLSW 9627

Query: 864  ASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKS- 922
              P     D + G    K ++   +      +    +  V + L+        + +++  
Sbjct: 9628 KMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFG 9687

Query: 923  -----DPLKKKTDRAP---PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYR- 973
                 + +++ T R P   P PP  +      ++++ L WK P   GG+ +T Y V    
Sbjct: 9688 IGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLA 9747

Query: 974  -EVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCE 1032
             +        WR+ N + V E  + + +L E   Y+F+V A+N AG+  PSA      C+
Sbjct: 9748 WDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQ 9807

Query: 1033 EWTIAVPGPPHSLKCSE 1049
                  P  P S+   E
Sbjct: 9808 R-----PDMPPSIDLKE 9819



 Score =  150 bits (380), Expect = 8e-36
 Identities = 169/756 (22%), Positives = 290/756 (38%), Gaps = 92/756 (12%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             T+    +++L  S++G P P +TW K  + +   A     II++      L ++  +  D
Sbjct: 23152 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA-----IIDTTESYSLLIVDKVNRYD 23206

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRF-HAGASTMPLSFGVTPYGYASRFEI 405
               +Y   A N  G+ SA   V V    G     +       ++ +++ +      +    
Sbjct: 23207 AGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNN 23266

Query: 406   HFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERA 465
             +  +K + +  R  +T++  C   +             YR          +  L  G   
Sbjct: 23267 YIVEKREAAM-RAFKTVTTKCSKTL-------------YR----------ISGLVEG--- 23299

Query: 466   TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
               T  +     E +Y I    GE  E   A +        +   P  P  ++ ++  K  
Sbjct: 23300 --TMYYFRVLPENIYGI----GEPCETSDAVL--------VSEVPLVPAKLEVVDVTKST 23345

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
             + ++W++P  DGGS + GY ++ C+ GT+ W +            VT L EG  Y+FR+R
Sbjct: 23346 VTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23405

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             A N+ G+  P      V   D      L+  P+       + T  + +  +  G P +L 
Sbjct: 23406 AQNEKGVSEPRETVTAVTVQD------LRVLPTID-----LSTMPQKTIHVPAGRPVELV 23454

Query: 646   VTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEG 705
             +  A R     SW   G +  E                +RV  E   K  +  + +    
Sbjct: 23455 IPIAGRPPPAASWFFAGSKLRES---------------ERVTVETHTKVAKLTIRETTIR 23499

Query: 706   KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESK 763
              +  + +   N  G    SE  +V ++ DK   P  P KI       TS+ +SWE  E  
Sbjct: 23500 DTGEYTLELKNVTGT--TSETIKVIIL-DKPGPPTGPIKI--DEIDATSITISWEPPELD 23554

Query: 764   DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823
                 L GY +E   A    W P + + V  S F    L  G  Y+FRV A N  G+  Y 
Sbjct: 23555 GGAPLSGYVVEQRDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYL 23613

Query: 824   QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTAS------RGRVHEASPPTFQKDALLGS 877
             Q SE IE +++I     P+          G+T +       G          +K+     
Sbjct: 23614 Q-SEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADR 23672

Query: 878   KPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPP 937
                   +P +      T +++  E  +  +T    + + +    S P+      APP  P
Sbjct: 23673 WVRVNKVPVTMTRYRSTGLTEGLE-YEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKP 23731

Query: 938   CDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYK 997
              +    ++ R S+ L W  P+  GG+++TGY +  ++V      +W + N        Y 
Sbjct: 23732 QNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQ---HEWTKCNTTPTKIREYT 23788

Query: 998   ISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE 1033
             +++L +   Y+F+V A N  G G P+ V    K  E
Sbjct: 23789 LTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTE 23824



 Score =  145 bits (366), Expect = 3e-34
 Identities = 132/461 (28%), Positives = 195/461 (42%), Gaps = 55/461 (11%)

Query: 367   VVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKF-DVSFGREGETMSLG 425
             V+ +   G F E    +GA        +T            D K+ DV     GET  L 
Sbjct: 18372 VIARNAAGNFSEPSDSSGA--------ITARDEIDAPNASLDPKYKDVIVVHAGETFVLE 18423

Query: 426   CRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG-ERATLTFSHLNKEDEGLYTIRV 484
               +   P      P++ W ++G  L  +     + S  ++ TL      + D G Y +++
Sbjct: 18424 ADIRGKPI-----PDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKL 18478

Query: 485   RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGY 544
                   +     V V D      G P  PL V  + A K Y+  +W  P  DGG+ I  Y
Sbjct: 18479 SNVGGTKSIPITVKVLDRP----GPPEGPLKVTGVTAEKCYL--AWNPPLQDGGANISHY 18532

Query: 545   FIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAA 604
              I+K E    SW+Q + T V+   + VT L+ G  YIFRV AVNK GIG P   S PV A
Sbjct: 18533 IIEKRETSRLSWTQVS-TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE-SGPVTA 18590

Query: 605   LDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSW-KPPGQ 663
              +P +                            PGPP+   V+  T+  +V++W +P   
Sbjct: 18591 CNPYKP---------------------------PGPPSTPEVSAITKDSMVVTWARPVDD 18623

Query: 664   RGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEP 723
              G E   Y +EK +     W + N +  +   R  +  L EG SY FRV   N+AGVGEP
Sbjct: 18624 GGTEIEGYILEKRDKEGVRWTKCNKKT-LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEP 18682

Query: 724   SEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSG 781
             SE +      D L  P  P     +  + +SV ++W +        + GY +E   A + 
Sbjct: 18683 SEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAAD 18742

Query: 782   KWEPCN-NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSE 821
             +W  C     ++G +FT   L     Y FR+ A+N+ G+ E
Sbjct: 18743 EWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGE 18783



 Score =  145 bits (365), Expect = 4e-34
 Identities = 179/719 (24%), Positives = 290/719 (40%), Gaps = 83/719 (11%)

Query: 638  PGPPTDLSVTEATRSYVVLSWKPP-GQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPR 696
            PGPP +    +  ++ V+  W+PP    G E I Y +EK +    + + +     ++  +
Sbjct: 8497 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCK 8556

Query: 697  FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
            +++  L EGK Y FRVR  N  G G P   ++  V  D    P AP K I    T  S++
Sbjct: 8557 YSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSML 8615

Query: 757  VSWEESKD-AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVN 815
            V W E KD    ++GY++E     S  W   N + +   +    GL+ G +Y+FRV A N
Sbjct: 8616 VKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAEN 8675

Query: 816  AAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDA-L 874
            AAG  ++S  S+       I     P   P ++D     T+S     E  PP F     +
Sbjct: 8676 AAGPGKFSPPSDPKTAHDPISPPGPP--IPRVTD-----TSSTTIELEWEPPAFNGGGEI 8728

Query: 875  LGSKPNKPSLPSSSQN--------LGQTEVSKVSETVQEELTPPPQKAAPQGK-SKSDPL 925
            +G   +K  + ++  +        + Q  V ++ E    +L      AA +G   ++ P+
Sbjct: 8729 VGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPV 8788

Query: 926  KKKTDRAPPSPPCDITCLESFR---------DSMVLGWKQPDKIGGAEITGYYVNYREVI 976
                 + PP+   D++     +          ++V G   P K+   E  G     R VI
Sbjct: 8789 TVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKE-EGELDKDRVVI 8847

Query: 977  DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
            D         NV   SE   K +  K++  Y   + A N  G    +A  E F       
Sbjct: 8848 D---------NVGTKSELIIKDALRKDHGRYV--ITATNSCGSKFAAARVEVFD------ 8890

Query: 1037 AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIK 1096
             VPGP   LK     +   +L W  P   G + +TG+ ++ K+AK     WR   E   +
Sbjct: 8891 -VPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM--HTWRQPIET--E 8945

Query: 1097 NVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG----TKEVVVNVDDDG 1152
                 + GL EG  Y FRV A N+ G G P ++ GP++A    G     + +        
Sbjct: 8946 RSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEI-GPILAVDPLGPPTSPERLTYTERTKS 9004

Query: 1153 VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
             I+L+++  +    S            D P  E  +K      +F    +D+  +Y   V
Sbjct: 9005 TITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRV 9064

Query: 1213 TDTDGIASS-------YLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQ 1265
               + I  S        +I ++E+   + L    +  T+ VK+   V I           
Sbjct: 9065 KAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHI----------- 9113

Query: 1266 AEKLSG--NAKVNYIFNEKEIFEGPK-----YKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
               ++G    K+ +  NE  + E P       K  + R+    E+ + K   ED+GTYT
Sbjct: 9114 PADVTGLPMPKIEWSKNE-TVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYT 9171



 Score =  139 bits (351), Expect = 2e-32
 Identities = 139/561 (24%), Positives = 228/561 (40%), Gaps = 59/561 (10%)

Query: 510  PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
            P  P+DV+      + + I+WK P  DGGS I+GY I+K   G + W +CN+  V    +
Sbjct: 8275 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8334

Query: 570  PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
               GL EG+ Y FRVRA N  GI  PSR + P  A+DP +  ++  R S     ++   +
Sbjct: 8335 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSL----EVKRGD 8390

Query: 630  EEPSEGIVPGPP-------TDLSV---TEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAG 679
            E   +  + G P        D +V    E  +    L  +  G+   E            
Sbjct: 8391 EIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLS 8450

Query: 680  TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 739
             +N ++  ++L V+       D        + ++  N  G+ +      V      LD P
Sbjct: 8451 IDNSKKGESQLRVR-------DSLRPDHGLYMIKVENDHGIAKAPCTVSV------LDTP 8497

Query: 740  KAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEA--SVAGSGKWEPCNNNPVKGSR 795
              P   +      TSV+  WE   D    E++ Y +E         +W    +  ++  +
Sbjct: 8498 GPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTST-LRHCK 8556

Query: 796  FTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLT 855
            ++   L+ G+ Y+FRVRA N  G       S+ +  K   G   +PD  P + D      
Sbjct: 8557 YSVTKLIEGKEYLFRVRAENRFGPGPPCV-SKPLVAKDPFGPPDAPDK-PIVED-----V 8609

Query: 856  ASRGRVHEASPPTFQKDALLGSKPNKPSLPS--------SSQNLGQTEVSKVSETVQEEL 907
             S   + + + P      +LG    K  + S        S  N  +  V  + E +    
Sbjct: 8610 TSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVF 8669

Query: 908  TPPPQKAAPQGK--SKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEI 965
                + AA  GK    SDP       +PP PP      ++   ++ L W+ P   GG EI
Sbjct: 8670 RVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEI 8728

Query: 966  TGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAV 1025
             GY+V+ + V      +W     K +    Y +  ++E   Y+ +V+A+N AG G P   
Sbjct: 8729 VGYFVDKQLV---GTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPG-- 8783

Query: 1026 SECFKCEEWTIAVPGPPHSLK 1046
                + +  T+A P  P +++
Sbjct: 8784 ----ETQPVTVAEPQEPPAVE 8800



 Score =  134 bits (337), Expect = 7e-31
 Identities = 227/973 (23%), Positives = 378/973 (38%), Gaps = 127/973 (13%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFI-----DKCEVGTDSWSQCNDTPV 564
             P  P+ +K     K+ + +SWK P  DGGSP+  Y +     D      ++W QCN   V
Sbjct: 9707  PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDV 9766

Query: 565   KFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQ 624
             +  +F V  L+EG  Y FRV+AVN  G      VS+P A + P +  R    PS     +
Sbjct: 9767  EELQFTVEDLVEGGEYEFRVKAVNAAG------VSKPSATVGPCDCQRPDMPPSID-LKE 9819

Query: 625   IIVTEEEPSEGIV---PGPPTDLSVTEATRSYVVLSW-KPPGQR--GHEGIMYFVEKCEA 678
              +  EE  +  IV    G P           +  L+W K P ++    E ++Y       
Sbjct: 9820  FMEVEEGTNVNIVAKIKGVP-----------FPTLTWFKAPPKKPDNKEPVLYDT----- 9863

Query: 679   GTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDI 738
                    VN  +   +    +       +  + +   N+  +G  S+   + V+G +   
Sbjct: 9864  ------HVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNN--LGTASKEMRLNVLG-RPGP 9914

Query: 739   PKAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRF 796
             P  P K   S + D  + +SW   KD    ++  Y IE   A    W   ++ P K   +
Sbjct: 9915  PVGPIK-FESVSAD-QMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP-KECTY 9971

Query: 797   TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTA 856
             T   L+ G  Y+FR+ A N  G+ E   DSE    +       +PD     S     +T 
Sbjct: 9972  TIPKLLEGHEYVFRIMAQNKYGIGE-PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTV 10030

Query: 857   S--RGRVHEASPPT----FQKDALLGSKPNKPSLPSSSQNLGQT-EVSKVSETVQEELTP 909
             +         SP T      KD            P  +  LG + +V+ + E    +   
Sbjct: 10031 NWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRV 10090

Query: 910   PPQKAAPQGKSK--SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                 AA  G +   SDP   +   APP PP      +  + S  L W  P K GG+++TG
Sbjct: 10091 YAINAAGVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTG 10149

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             Y V Y+E  +G   +W +   K V      ++ LKE   Y+F+V A+N+AG+G P  V++
Sbjct: 10150 YIVEYKE--EG-KEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD 10206

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVH-----SGRTPVTGYFVDLKEAKA 1082
               + ++  ++   P   L  S   +D +V+     +      SG+ P T   V     + 
Sbjct: 10207 VIEMKDRLVS---PDLQLDASV--RDRIVVHAGGVIRIIAYVSGKPPPT---VTWNMNER 10258

Query: 1083  KEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS------DLAGPVVAE 1136
                Q   +   AI +  + ++  +     V+ + A N+AG  K +      D+ GPV   
Sbjct: 10259 TLPQEATIETTAISS-SMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPV--- 10314

Query: 1137  TRPGTKEVVVNVDDDGVISLNF--ECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTK 1194
                GT  +  N+ ++      F  E D  +P + +   K     E   R         T+
Sbjct: 10315 ---GTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEK----RESDRRAWTPVTYTVTR 10367

Query: 1195  MTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEI 1254
                   G+     Y   +   + I     ++  E    L +      P  P   +L V+ 
Sbjct: 10368 QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSE---ALVIREPITVPERP--EDLEVKE 10422

Query: 1255  LEKGQVRFWMQAEKLSGNAK-VNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDE 1313
             + K  V       K  G ++ +NY+   + I      K H   N  ++         ++ 
Sbjct: 10423 VTKNTVTLTWNPPKYDGGSEIINYVLESRLI---GTEKFHKVTNDNLLSRKYTVKGLKEG 10479

Query: 1314  GTYTFQLQ------DGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWE 1367
              TY +++        GK +  +  +   D         +F+ +  IR  G  F       
Sbjct: 10480 DTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIR-VGEAFA------ 10532

Query: 1368  VTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKK--DAGI 1425
             +TG  +   K KV+         W+KDE ++  D++   K    TL + +   K  D+G 
Sbjct: 10533 LTGRYSGKPKPKVS---------WFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGK 10583

Query: 1426  YEVILKDDRGKDK 1438
             Y V++++  G  K
Sbjct: 10584 YCVVVENSTGSRK 10596



 Score =  131 bits (330), Expect = 5e-30
 Identities = 219/1039 (21%), Positives = 387/1039 (37%), Gaps = 164/1039 (15%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             T+    ++ L  ++ G PEP++ W K    +++     K  ++      T  I  CD  D
Sbjct: 22753 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCE---KVSLQYTGKRATAVIKFCDRSD 22809

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYK-----GEFDETRFHAGASTMPLSFGVTPYGYAS 401
             + +Y  +  N  G  +   SV+VK        G+   +R      T+  S      G   
Sbjct: 22810 SGKYTLTVKNASG--TKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGG--- 22864

Query: 402   RFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS 461
                                            EI H+  E +        S   WV  +  
Sbjct: 22865 ------------------------------AEITHYIVERR------ETSRLNWV--IVE 22886

Query: 462   GERATLTF--SHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVK 517
             GE  TL++  + L K +E ++ +R   + G      S  +  R++   I   P  P +V 
Sbjct: 22887 GECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNS-FTIPSPPGIPEEV- 22944

Query: 518   CLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCN-DTPVKFARFPVTGLIE 576
                  K++III W +P  DGG+ I  Y +DK E  +  W++ N D  V   R  VT L+E
Sbjct: 22945 --GTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 23002

Query: 577   GRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGI 636
             G  Y FRV AVN  G   PS  S  ++  +P+                            
Sbjct: 23003 GCDYQFRVTAVNAAGNSEPSEASNFISCREPS---------------------------Y 23035

Query: 637   VPGPPTDLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSP 695
              PGPP+   V + T+  + L+W KP    G + + Y +E  E  T+ W RV+T   +++ 
Sbjct: 23036 TPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 23095

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
              F + DL  G+ Y FRV   N  G+ E SE+       ++++IP                
Sbjct: 23096 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP---------------- 23139

Query: 756   VVSWEESKDAKELV----GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLV-TGQSY-IF 809
                 E + D K+ V    G  +   V+ SG+  P      +G       ++ T +SY + 
Sbjct: 23140 --DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLL 23197

Query: 810   RVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGR--VHEASPP 867
              V  VN     +Y+ ++E         G  S  V   + D PG   + + +    ++   
Sbjct: 23198 IVDKVNRYDAGKYTIEAE------NQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTI 23251

Query: 868   TFQKDALLGSKPNKPSL---PSSSQNLGQTEVSKVSETVQE-----ELTPPPQKAAPQGK 919
             T++   + G  P    +     ++    +T  +K S+T+       E T    +  P+  
Sbjct: 23252 TWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENI 23311

Query: 920   SKSDPLKKKTDRA----PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREV 975
                    + +D       P  P  +  ++  + ++ L W++P   GG+ +TGY +   E 
Sbjct: 23312 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVL---EA 23368

Query: 976   IDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWT 1035
                   +W +      +   + +++L E   Y F++ A N  G+  P         ++  
Sbjct: 23369 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23428

Query: 1036  I-----AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGL 1090
             +         P  ++     R   LV+    P+     P   +F     +K +E + R  
Sbjct: 23429 VLPTIDLSTMPQKTIHVPAGRPVELVI----PIAGRPPPAASWF--FAGSKLRESE-RVT 23481

Query: 1091  NEAAIKNVYLKVR--GLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNV 1148
              E   K   L +R   +++   Y   ++ +     G  S+    ++ + +PG     + +
Sbjct: 23482 VETHTKVAKLTIRETTIRDTGEYTLELKNV----TGTTSETIKVIILD-KPGPPTGPIKI 23536

Query: 1149  DDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPR---LEVESKGNKTKMTFKDLGMDDL 1205
             D+    S+    +          S   V   D+ R   L V     ++   F  L   + 
Sbjct: 23537 DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNE 23596

Query: 1206  GIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQ 1265
              ++    T+  GI  SYL  E     ++      + P  P   ++  ++   G    W  
Sbjct: 23597 YVFRVAATNRFGI-GSYLQSE-----VIECRSSIRIPGPPETLQI-FDVSRDGMTLTWYP 23649

Query: 1266  AEKLSGNAKVNYIFNEKEI 1284
              E   G+    YI   KE+
Sbjct: 23650 PEDDGGSQVTGYIVERKEV 23668



 Score =  131 bits (329), Expect = 6e-30
 Identities = 97/326 (29%), Positives = 140/326 (42%), Gaps = 46/326 (14%)

Query: 418  EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDE 477
            EGE +S+       P      P + W+++G  +  S  +        A L      + D 
Sbjct: 8095 EGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8149

Query: 478  GLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAV 535
            G+YTI +  ++G               + ++ G P    D+K  +  K    ++W+ P  
Sbjct: 8150 GIYTITLENKLGSA---------TASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 8200

Query: 536  DGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFP 595
            DGG+PIL Y +++ E G  ++        K + + V  LI    Y FRV+AVNK+G G  
Sbjct: 8201 DGGTPILHYVLERREAGRRTYIPVMSGENKLS-WTVKDLIPNGEYFFRVKAVNKVGGGEY 8259

Query: 596  SRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVV 655
              +  PV A DP +                            P PP D+ V   T   + 
Sbjct: 8260 IELKNPVIAQDPKQP---------------------------PDPPVDVEVHNPTAEAMT 8292

Query: 656  LSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRC 714
            ++WKPP   G   IM Y +EK   G E W+R N  L V    +    L EGK Y FRVR 
Sbjct: 8293 ITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRA 8351

Query: 715  SNSAGVGEPSEATEVTVVGDKLDIPK 740
             N+AG+ EPS AT  T   D +D PK
Sbjct: 8352 ENAAGISEPSRATPPTKAVDPIDAPK 8377



 Score =  129 bits (323), Expect = 3e-29
 Identities = 129/471 (27%), Positives = 187/471 (39%), Gaps = 95/471 (20%)

Query: 288   VWEKENVKLHCSIAGWPEPRVTWYK-------NQVPINVHANPGKYIIESRYGMHTLEIN 340
             V E  NV +   I G P P +TW+K       N+ P+    +  K +++      TL I 
Sbjct: 9823  VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTC---TLVIP 9879

Query: 341   GCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYA 400
                  DT  Y  +A+N  G  S               E R +      P      P G  
Sbjct: 9880  QSRRSDTGLYTITAVNNLGTAS--------------KEMRLNVLGRPGP------PVG-P 9918

Query: 401   SRFEIHFDDKFDVS-FGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTL 459
              +FE    D+  +S F  + +  S     VI                    +   WV   
Sbjct: 9919  IKFESVSADQMTLSWFPPKDDGGSKITNYVIEKR---------------EANRKTWVHVS 9963

Query: 460   WSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGA------PAAP 513
                +  T T   L +  E ++ I  +        + Y      D+E E A      P AP
Sbjct: 9964  SEPKECTYTIPKLLEGHEYVFRIMAQ--------NKYGIGEPLDSEPETARNLFSVPGAP 10015

Query: 514   LDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKF----ARF 569
                      ++ + ++W++P  DGGSP+ GY+++  +  +  W + N  P+K       +
Sbjct: 10016 DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSY 10075

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGLIEG  Y FRV A+N  G+G  S  S+P  A DP           AP         
Sbjct: 10076 KVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPI----------AP--------- 10116

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT 688
                     PGPP    VT+ T+S   L W PP + G   +  Y VE  E G E W++   
Sbjct: 10117 --------PGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEK-GK 10166

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 739
             +  V+  +  +  L EG  Y FRVR  N AG+GEP E T+V  + D+L  P
Sbjct: 10167 DKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP 10217



 Score =  125 bits (313), Expect = 5e-28
 Identities = 183/774 (23%), Positives = 298/774 (38%), Gaps = 129/774 (16%)

Query: 274   LHAPEFIIKP---RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIES 330
             L APE  I     ++H V    +++L  +  G P P   W K    +++ A+     I +
Sbjct: 22047 LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD-----IHT 22101

Query: 331   RYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
                  TL +  C+  D  +Y  +  N  G  S   +V V    G              P+
Sbjct: 22102 TDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-----------PGPI 22150

Query: 391   SFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPL 450
             +F     G A+                +   +  G R      I H+  E +        
Sbjct: 22151 TFKDVTRGSATLMW-------------DAPLLDGGAR------IHHYVVEKR------EA 22185

Query: 451   SPSKWVQTLWSGERATLTFSHLNKEDEGL-YTIRVRMGEYYEQYSAYVFVRDADAEIEGA 509
             S   W Q +   E+ T     +N   EG+ Y  RV     Y     Y       A  + A
Sbjct: 22186 SRRSW-QVI--SEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPA 22242

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P   LDV  ++ +K   +++W +P  DGGS I GY ++  + G+D W +   T  K   F
Sbjct: 22243 PPRRLDV--VDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT--KQLTF 22298

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTG---QII 626
              V  L+E   Y FRV+A N  G   P      V   +P      +  P+A  TG   Q+I
Sbjct: 22299 TVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEP------QIEPTADLTGITNQLI 22352

Query: 627   VTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRV 686
               +         G P  + V  + R    ++WK    R        +++ +  +    + 
Sbjct: 22353 TCK--------AGSPFTIDVPISGRPAPKVTWKLEEMR--------LKETDRVSITTTKD 22396

Query: 687   NTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKII 746
              T L VK       D   G S  + +   N+AGV   + +  V V+G    +    G I 
Sbjct: 22397 RTTLTVK-------DSMRGDSGRYFLTLENTAGV--KTFSVTVVVIGRPGPV---TGPIE 22444

Query: 747   PSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTG 804
              S  +  S V+SW E KD    E+  Y +E   +G+  W+  N++ VK ++     L   
Sbjct: 22445 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKY 22503

Query: 805   QSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV--- 861
               Y FRV + N  G+S+  + +  I           P V P+    P     S   +   
Sbjct: 22504 MEYSFRVSSENRFGVSKPLESAPII--------AEHPFVPPSAPTRPEVYHVSANAMSIR 22555

Query: 862   -----HEASPPTF-------QKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTP 909
                  H+             +++ +L  K NK  +P    N    +V+ + E ++ +   
Sbjct: 22556 WEEPYHDGGSKIIGYWVEKKERNTILWVKENK--VPCLECNY---KVTGLVEGLEYQFRT 22610

Query: 910   PPQKAAPQGKSK--SDPLKKKTDRAPPSPP--CDITCLESFRDSMVLGWKQPDKIGGAEI 965
                 AA   K+   S P+  +     P  P   D+T     R ++ L W  P   GG+++
Sbjct: 22611 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVT-----RSTVSLIWSAPAYDGGSKV 22665

Query: 966   TGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GY +  + V +   G+W + N   VS+  + ++ L E   Y+F+V A N AG+
Sbjct: 22666 VGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGV 22719



 Score =  122 bits (307), Expect = 2e-27
 Identities = 234/997 (23%), Positives = 368/997 (36%), Gaps = 139/997 (13%)

Query: 508  GAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFA 567
            G P +P  +   E  K  I + WK+P  +GGSPI GY I+K       + + N       
Sbjct: 8988 GPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTT 9047

Query: 568  RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALD---PAEKARLKSRPSAPWTGQ 624
             F V  L E + Y FRV+AVN++G   PS     V   D   P  K RL  R        
Sbjct: 9048 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDT----- 9102

Query: 625  IIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQ 684
            I V   EP    +P   T L + +       + W     +    I    +  +   E   
Sbjct: 9103 IKVKAGEPVH--IPADVTGLPMPK-------IEWS----KNETVIEKPTDALQITKEEVS 9149

Query: 685  RVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGK 744
            R   +  +  P+    D        + V  SN  G    +   EV       D P  P  
Sbjct: 9150 RSEAKTELSIPKAVREDKGT-----YTVTASNRLGSVFRNVHVEV------YDRPSPPRN 9198

Query: 745  IIPSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGK--WEPCNNNPVKGSRFTCHG 800
            +  +     S  ++W+   D    E+  Y I+   A   K  WE   N  V+  R+    
Sbjct: 9199 LAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVE-KRYGIWK 9257

Query: 801  LVTGQSYIFRVRAVNAAGLSEYSQDSEAI--------------EVKAAIGGGVSPDVCPA 846
            L+    Y FRVRAVN  G+S+  +  + +              +V A   G +     P 
Sbjct: 9258 LIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPP 9317

Query: 847  LSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEE 906
            L +    +T       E   P +       S+ ++  +        +  V ++ E V+ +
Sbjct: 9318 LDNGGSPITGYWLEKREEGSPYW-------SRVSRAPITKVGLKGVEFNVPRLLEGVKYQ 9370

Query: 907  LTPPPQKAAPQG--KSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
                   AA  G     SDP        PP PP      +  + S+ LGWK P K GG+ 
Sbjct: 9371 FRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSP 9430

Query: 965  ITGYYVNYREVIDGVPGKWREANV--KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
            I GY V  +E  +G    W+  N   K ++     + NLKE   Y+F+V A+N AG   P
Sbjct: 9431 IKGYIVEMQE--EGTTD-WKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEP 9487

Query: 1023 SAVSECFKC----EEWTIAVP-GPPHSLKCSEVRKDSLVLQWKPPVHSGR-TPVTGYFVD 1076
            S  +         EE  + +  G    L C    +  +     P V  GR TP + +  D
Sbjct: 9488 SDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRI-----PAVIKGRPTPKSSWEFD 9542

Query: 1077 LKEAKAKEDQWRGLNE-----AAIKNVYLKVRGLKEGVSYVFRVRAINQAGVG------K 1125
             K  KA +D    + E      A  +  + +   K   +  + + A N+AG        K
Sbjct: 9543 GKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVK 9602

Query: 1126 PSDLAGP-----VVAETRPGTKEVVVNVDDDGVISLN-FECDKMTPKSEFSWSKDYVSTE 1179
              D+ GP     V   TR   +      DDDG   +  +  +K T   + +W+K      
Sbjct: 9603 VMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGK-AWTK------ 9655

Query: 1180 DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEH 1239
                  V      T     DL  +    +     +  GI        E ++R  A    +
Sbjct: 9656 ------VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPV----ETIQRTTARDPIY 9705

Query: 1240 KFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFE--GPKYKMHIDRN 1297
              P  P+K  L + ++ K  V    +  K  G + V +   E   ++  G K +     N
Sbjct: 9706 P-PDPPIK--LKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN 9762

Query: 1298 TGIIEMFMEKLQDEDEG-TYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQ 1356
               +E     ++D  EG  Y F++   KA N + V          +  A     +  R  
Sbjct: 9763 KRDVEELQFTVEDLVEGGEYEFRV---KAVNAAGVS---------KPSATVGPCDCQRPD 9810

Query: 1357 GPHFVEYLSW-EVTGECNVLLKCKVANIKKETHIVWYK------DEREISVDEKHDFK-- 1407
             P  ++   + EV    NV +  K+  +   T + W+K      D +E  + + H  K  
Sbjct: 9811 MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPT-LTWFKAPPKKPDNKEPVLYDTHVNKLV 9869

Query: 1408 -DGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
             D  CTL+I +  + D G+Y +   ++ G     ++L
Sbjct: 9870 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9906



 Score =  121 bits (304), Expect = 5e-27
 Identities = 115/467 (24%), Positives = 177/467 (37%), Gaps = 86/467 (18%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             TV   + ++L   + G P P V W K++   ++  +P +  I++R       +      D
Sbjct: 11907 TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSD 11965

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
               +Y  +A N  G   AYA+V V    G     +                          
Sbjct: 11966 GGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKI------------------------- 12000

Query: 407   FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                  DVS  R        C V   P       EIQ Y     L   +  + +WS   AT
Sbjct: 12001 ----VDVSSDR--------CTVCWDPPEDDGGCEIQNY----ILEKCETKRMVWSTYSAT 12044

Query: 467   L-----TFSHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCL 519
             +     T + L + +E ++ +R   ++G      S  V  +         P  P   +  
Sbjct: 12045 VLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTK----YDKPGRPDPPEVT 12100

Query: 520   EANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRS 579
             + +K+ + + W  P  DGG  I GYF++K E  +  W   N + +   R  V  L+    
Sbjct: 12101 KVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHE 12160

Query: 580   YIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPG 639
             Y FRV+A N++GIG PS  S PV A DP E                            PG
Sbjct: 12161 YQFRVKAENEIGIGEPSLPSRPVVAKDPIEP---------------------------PG 12193

Query: 640   PPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCE------AGTENWQRVNTELPVK 693
             PPT+  V + T+  + L W  P   G   I+ +V +        +  E W+R N    + 
Sbjct: 12194 PPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLV 12253

Query: 694   SPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
                F +  L E + Y FRV   N  G+G P+E  E     + L+ P+
Sbjct: 12254 RKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPE 12300



 Score =  120 bits (300), Expect = 1e-26
 Identities = 118/471 (25%), Positives = 184/471 (39%), Gaps = 81/471 (17%)

Query: 277   PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
             P   +   ++++   E++K+   + G P P ++W K+  P+       +  +E       
Sbjct: 18007 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLK---QTTRVNVEETATSTV 18063

Query: 337   LEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTP 396
             L I   + +D  +Y  +A N  G  +   SV+V    G                     P
Sbjct: 18064 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--------------------PP 18103

Query: 397   YGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWV 456
              G     E+  D    V    E    + GC++      K       W+     ++     
Sbjct: 18104 VGPVRFDEVSAD---FVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVA----- 18155

Query: 457   QTLWSGERATLTFSHLNKEDEGLYTIRV----RMGEYYEQYSAYVFVRDADAEIEGAPAA 512
                    R T+  + L    E  Y  R+    R G+     S  V V+    E  G P  
Sbjct: 18156 -------RTTIKITKLKTGTE--YQFRIFAENRYGKSAPLDSKAVIVQYPFKE-PGPPGT 18205

Query: 513   PLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVT 572
             P        +KD +++ W +P  DGG+ I+GY +++ E  +  W + N TP++  +F  T
Sbjct: 18206 PF---VTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTT 18262

Query: 573   GLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEP 632
             GL EG  Y F+V A N +GIG PS+VSE   A DP +                       
Sbjct: 18263 GLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDP---------------------- 18300

Query: 633   SEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELP 691
                  PG P  + +   TR+ V L WK P   G   I  Y VEK +     W + +    
Sbjct: 18301 -----PGRPEAIVI---TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASF-TN 18351

Query: 692   VKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKA 741
             V    F +  L E + Y FRV   N+AG   EPS+++      D++D P A
Sbjct: 18352 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNA 18402



 Score =  117 bits (293), Expect = 9e-26
 Identities = 95/316 (30%), Positives = 144/316 (45%), Gaps = 39/316 (12%)

Query: 510  PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
            P+ PLD+   +A + +I I+WK P  +GGSPI+GY ++ C VGT+ W + N  P+K  +F
Sbjct: 7980 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 8039

Query: 570  PV-TGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVT 628
             V  G++  + Y+ RVRAVN +G+  PS +SE V A DP  K  +        T  IIV 
Sbjct: 8040 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLE-----THDIIVI 8094

Query: 629  EEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNT 688
            E E     +P P   + V         +SW   G+         V+  +  T     ++ 
Sbjct: 8095 EGEKLS--IPVPFRAVPVP-------TVSWHKDGKE--------VKASDRLTMKNDHISA 8137

Query: 689  ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPS 748
             L V  P+    D        + +   N   +G  + +  V V+G    +P     I  S
Sbjct: 8138 HLEV--PKSVRADAG-----IYTITLENK--LGSATASINVKVIG----LPGPCKDIKAS 8184

Query: 749  RNTDTSVVVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQS 806
              T +S  ++WE  E      ++ Y +E   AG   + P  +   K S +T   L+    
Sbjct: 8185 DITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLS-WTVKDLIPNGE 8243

Query: 807  YIFRVRAVNAAGLSEY 822
            Y FRV+AVN  G  EY
Sbjct: 8244 YFFRVKAVNKVGGGEY 8259



 Score =  117 bits (292), Expect = 1e-25
 Identities = 89/308 (28%), Positives = 141/308 (45%), Gaps = 18/308 (5%)

Query: 922   SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPG 981
             SDP+  +     P  P          +S+ L W +P+  GG+EI  Y +  RE       
Sbjct: 21835 SDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKST--- 21891

Query: 982   KW-REANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
             +W +  + + +SE  +K++ L E   Y+F V A N AG+G  S +S   KC E  +  PG
Sbjct: 21892 RWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCRE-PVNPPG 21950

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVY 1099
             PP  +K ++  K ++ L+W  PV  G   + GY +++   KA    W  +N EA +K  Y
Sbjct: 21951 PPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEM--CKADLGDWHKVNAEACVKTRY 22008

Query: 1100  LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVV-------NVDDDG 1152
               V  L+ G  Y FRV AIN AG G   ++ G + A  R    E+ +       +V   G
Sbjct: 22009 -TVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAG 22067

Query: 1153  VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
                  F   +  P     WSK    +  S R ++ +  + + +T ++   +D G Y+  V
Sbjct: 22068 ASIRLFIAYQGRPTPTAVWSKP--DSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV 22125

Query: 1213  TDTDGIAS 1220
              +  G  S
Sbjct: 22126 ENNSGSKS 22133



 Score =  116 bits (290), Expect = 2e-25
 Identities = 133/548 (24%), Positives = 220/548 (40%), Gaps = 61/548 (11%)

Query: 638   PGPPTD-LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             PGPP   +   E +  +VV+SW+PP   G   I  Y VEK +  T  W  V+    V   
Sbjct: 18100 PGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSAT--VART 18157

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
                +  L  G  Y FR+   N  G   P ++  V +V      P  PG    +  +   +
Sbjct: 18158 TIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAV-IVQYPFKEPGPPGTPFVTSISKDQM 18216

Query: 756   VVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRA 813
             +V W E  +    +++GY++E     S  W   N  P++ ++F   GL  G  Y F+V A
Sbjct: 18217 LVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA 18276

Query: 814   VNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG-----LTASRGRVHEASPPT 868
              N  G+ + S+ SE           V+ D C    D PG      +T +   +    P  
Sbjct: 18277 ENIVGIGKPSKVSECF---------VARDPC----DPPGRPEAIVITRNNVTLKWKKPAY 18323

Query: 869   FQKDALLGSKPNKPSLP------SSSQNLGQTE--VSKVSETVQEELTPPPQKAAPQGKS 920
                  + G    K  LP      +S  N+ +TE  VS + E  + E     + AA     
Sbjct: 18324 DGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSE 18383

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
              SD     T R     P + +    ++D +V+        G   +    +  + + D V 
Sbjct: 18384 PSDSSGAITARDEIDAP-NASLDPKYKDVIVV------HAGETFVLEADIRGKPIPDVVW 18436

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAA------MNMAGLGAPSAVSECFKCEEW 1034
              K  +   +  +    K +  K  +V +  +        + ++ +G   ++    K    
Sbjct: 18437 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVK---- 18492

Query: 1035  TIAVPGPPHS-LKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
              +  PGPP   LK + V  +   L W PP+  G   ++ Y ++ +E       W  ++  
Sbjct: 18493 VLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS--WTQVS-T 18549

Query: 1094  AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA------ETRPGTKEVVVN 1147
              ++ +  KV  L  G  Y+FRV A+N+ G+G+P + +GPV A         P T EV   
Sbjct: 18550 EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE-SGPVTACNPYKPPGPPSTPEVSAI 18608

Query: 1148  VDDDGVIS 1155
               D  V++
Sbjct: 18609 TKDSMVVT 18616



 Score =  115 bits (289), Expect = 3e-25
 Identities = 166/757 (21%), Positives = 275/757 (36%), Gaps = 129/757 (17%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             E +K++  IAG P P ++W K+ + I   A   +  I S      L +  C   DT QY 
Sbjct: 19500 EVLKINADIAGRPLPVISWAKDGIEIEERA---RTEIISTDNHTLLTVKDCIRRDTGQYV 19556

Query: 352   ASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF-GVTPYGYASRFEIHFDDK 410
              +  NV G  S   +  V       D+    AG    PL   G+T             +K
Sbjct: 19557 LTLKNVAGTRSVAVNCKV------LDKPGPPAG----PLEINGLTA------------EK 19594

Query: 411   FDVSFGREGET--MSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGE--RAT 466
               +S+GR  E     +   +V   E  H    + W              T+  GE    +
Sbjct: 19595 CSLSWGRPQEDGGADIDYYIVEKRETSH----LAW--------------TICEGELQMTS 19636

Query: 467   LTFSHLNKEDEGLYTI----RVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEAN 522
                + L K +E ++ +    +  +GE  E     V ++  D      P+ P  ++     
Sbjct: 19637 CKVTKLLKGNEYIFRVTGVNKYGVGEPLES----VAIKALDPFT--VPSPPTSLEITSVT 19690

Query: 523   KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIF 582
             K+ + + W +P  DGGS I GY I++ E  +  W + N  PV   R   TGL EG  Y +
Sbjct: 19691 KESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEY 19750

Query: 583   RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
             RV A N  G+  PS  S  + A DP                             +P PP+
Sbjct: 19751 RVYAENAAGLSLPSETSPLIRAEDPV---------------------------FLPSPPS 19783

Query: 643   DLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFD 701
                + ++ ++ + ++W KP    G     Y VE  ++   +W+     L  +   + +  
Sbjct: 19784 KPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL--RGTEYTISG 19841

Query: 702   LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK-------LDIPKAPGKIIPSRNTDTS 754
             L  G  Y FRV+  N  G  +PS++++  +  ++       +D       I+ +  + T 
Sbjct: 19842 LTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTM 19901

Query: 755   VV---------VSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQ 805
              V         V W +         Y        S   E  N N       T   +++  
Sbjct: 19902 TVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 19961

Query: 806   SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEAS 865
             S    V+ ++  G        +  +  A +   V         +  GG       + +  
Sbjct: 19962 SLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV--------PENDGGAPVKNYHIEKRE 20013

Query: 866   PPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPL 925
                  K A +    N   L     NL +  +     + + E          +G       
Sbjct: 20014 A---SKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEG------- 20063

Query: 926   KKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWRE 985
              K T++  P     +T +   +DS+ L W +P+  GG+ I  Y V   E ++     W +
Sbjct: 20064 VKITEKPSPPEKLGVTSIS--KDSVSLTWLKPEHDGGSRIVHYVV---EALEKGQKNWVK 20118

Query: 986   ANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
               V       + +S L+EN  Y F+V A N AGL  P
Sbjct: 20119 CAV--AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20153



 Score =  113 bits (282), Expect = 2e-24
 Identities = 82/300 (27%), Positives = 136/300 (45%), Gaps = 26/300 (8%)

Query: 934   PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
             P PP          D M L W  P   GG+E+TG++V  +E    +   W++ N   +S 
Sbjct: 21452 PGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSIL---WQKVNTSPISG 21508

Query: 994   EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVP--GPPHSLKCSEVR 1051
               Y+ + L E + YQF+V A N AGL +PS  S+      +T+AV    PP +    +V 
Sbjct: 21509 REYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK------FTLAVSPVDPPGTPDYIDVT 21562

Query: 1052  KDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSY 1111
             ++++ L+W PP+  G + + GY ++ ++     ++W   N   +      V GL  G  Y
Sbjct: 21563 RETITLKWNPPLRDGGSKIVGYSIEKRQGN---ERWVRCNFTDVSECQYTVTGLSPGDRY 21619

Query: 1112  VFRVRAINQAG-VGKPSDLAGPVVAETRPGTKEVVVNVDD---DGVISLNFECDKMT--- 1164
              FR+ A N  G +  PS  +G ++  TR      +V       DG+I  + E  ++    
Sbjct: 21620 EFRIIARNAVGTISPPSQSSGIIM--TRDENVPPIVEFGPEYFDGLIIKSGESLRIKALV 21677

Query: 1165  ---PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
                P    +W KD V  E    +E+      T +  +D   D  G+Y+ +  +  G A +
Sbjct: 21678 QGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKA 21737



 Score =  112 bits (279), Expect = 4e-24
 Identities = 71/232 (30%), Positives = 103/232 (44%), Gaps = 28/232 (12%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P  P   +     KD ++++W +P  DGG+ I GY ++K +     W++CN   +   R 
Sbjct: 18597 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRL 18656

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGL EG SY FRV A N  G+G PS  S    A D                       
Sbjct: 18657 RVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDAL--------------------- 18695

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT 688
                     PGPP++  VT+ +RS V L+W  P   G   +  Y VE  EA  + W     
Sbjct: 18696 ------YPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTP 18749

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
                ++  +F +  L E   Y FR+   NS GVGEP+      V  ++++ P+
Sbjct: 18750 PTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18801



 Score =  108 bits (269), Expect = 6e-23
 Identities = 127/511 (24%), Positives = 214/511 (41%), Gaps = 52/511 (10%)

Query: 638   PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
             PGPP  + + E +   + +SW PP   G   I  Y VEK E  +  W  V+  +   S +
Sbjct: 19183 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIK 19242

Query: 697   FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
               +  L  G  Y FRV   N  G    SE++ V V       P  PG       T ++++
Sbjct: 19243 --IVRLTTGSEYQFRVCAENRYGKSSYSESSAV-VAEYPFSPPGPPGTPKVVHATKSTML 19299

Query: 757   VSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             V+W+   +     ++GY++E     S  W   N   +  ++    GL  G  Y +RV A 
Sbjct: 19300 VTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAE 19359

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVC-PALSDEPGGLTASRGRVHEASPPTFQKDA 873
             N AG+ + S+  E +  +         D C P    E   +T     +  + P       
Sbjct: 19360 NIAGIGKCSKSCEPVPAR---------DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAK 19410

Query: 874   LLGSKPNKPSLPS------SSQNLGQT--EVSKVSETVQEELTPPPQKAAPQGKSKSD-- 923
             + G    +  LP       +  N+ +T  EV++++E  + E     + AA      S+  
Sbjct: 19411 ITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSEST 19470

Query: 924   -PLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGY---YVNYREVIDGV 979
              P+  K D  PP    D+     FRD +V+   +  KI  A+I G     +++ +  DG+
Sbjct: 19471 GPIIVKDDVEPPRVMMDV----KFRDVIVVKAGEVLKI-NADIAGRPLPVISWAK--DGI 19523

Query: 980   PGKWREANVKAVSEEAYKISNLKENM---VYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
               + R A  + +S + + +  +K+ +     Q+ +   N+AG       S    C+   +
Sbjct: 19524 EIEER-ARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG-----TRSVAVNCK--VL 19575

Query: 1037  AVPGPPHS-LKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 1095
               PGPP   L+ + +  +   L W  P   G   +  Y V+ +E       W  + E  +
Sbjct: 19576 DKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE--TSHLAWT-ICEGEL 19632

Query: 1096  KNVYLKVRGLKEGVSYVFRVRAINQAGVGKP 1126
             +    KV  L +G  Y+FRV  +N+ GVG+P
Sbjct: 19633 QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 19663



 Score =  107 bits (267), Expect = 1e-22
 Identities = 81/279 (29%), Positives = 125/279 (44%), Gaps = 45/279 (16%)

Query: 462  GERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEA 521
            G ++ L      ++D G Y I         +++A      A  E+   P   LD+K +  
Sbjct: 8851 GTKSELIIKDALRKDHGRYVITAT-NSCGSKFAA------ARVEVFDVPGPVLDLKPVVT 8903

Query: 522  NKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYI 581
            N+   +++W  P  DGGS I G+ I++ +    +W Q  +T  + ++  +TGL+EG+ Y 
Sbjct: 8904 NRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIET--ERSKCDITGLLEGQEYK 8961

Query: 582  FRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPP 641
            FRV A NK G G P  +  P+ A+DP                               GPP
Sbjct: 8962 FRVIAKNKFGCGPPVEIG-PILAVDPL------------------------------GPP 8990

Query: 642  TD---LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRF 697
            T    L+ TE T+S + L WK P   G   I  Y +EK      +++RVN  L   +  F
Sbjct: 8991 TSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSF 9049

Query: 698  ALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
             + +L E + Y FRV+  N  G  EPS    V +  D++
Sbjct: 9050 LVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEV 9088



 Score =  103 bits (256), Expect = 2e-21
 Identities = 71/193 (36%), Positives = 91/193 (47%), Gaps = 7/193 (3%)

Query: 638   PGPPTD-LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             PGPP   L VT  T     L+W PP Q G   I  Y +EK E    +W +V+TE  V++ 
Sbjct: 18497 PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTE--VQAL 18554

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
              + +  L  G  Y FRV   N  G+GEP E+  VT   +    P  P     S  T  S+
Sbjct: 18555 NYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTAC-NPYKPPGPPSTPEVSAITKDSM 18613

Query: 756   VVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRA 813
             VV+W    D    E+ GY +E       +W  CN   +   R    GL  G SY FRV A
Sbjct: 18614 VVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAA 18673

Query: 814   VNAAGLSEYSQDS 826
              NAAG+ E S+ S
Sbjct: 18674 ENAAGVGEPSEPS 18686



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 161/728 (22%), Positives = 271/728 (37%), Gaps = 135/728 (18%)

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             VF R  DA     P  P + K  + ++  + ++W +P  DGG+P+ GY ++  E   D W
Sbjct: 18687 VFYRACDALYP--PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW 18744

Query: 557   SQCND-TPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKS 615
             + C   T ++  +F VT L E   Y FR+ A+N  G+G P+ +   V A +  E   ++ 
Sbjct: 18745 TTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIEL 18804

Query: 616   RPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQ---RGHEGIMYF 672
                     +++V                L  +   R +V +  +P  +      EGI+  
Sbjct: 18805 DAD---LRKVVV----------------LRASATLRLFVTIKGRPEPEVKWEKAEGIL-- 18843

Query: 673   VEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV 732
                         R   E+        + ++    S  + +   N++G    S+   V V 
Sbjct: 18844 ----------TDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSG----SKTAFVNV- 18888

Query: 733   GDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCNNNP 790
                LD P AP  +        SV +SWE        ++  Y +E        +    NN 
Sbjct: 18889 -RVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNC 18947

Query: 791   VKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDE 850
              K + F    L  G SY FRV A N  G+   ++ +E ++V             P L   
Sbjct: 18948 TK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSE-----------PPL--P 18993

Query: 851   PGGLTASRGRVHEASPPTFQKDALLGSKPN----KPSLPSSSQNLGQTEVSKVSETVQEE 906
             PG +T      + A+    + ++  GSK      +     S +    T+V  +  T+   
Sbjct: 18994 PGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATI-SG 19052

Query: 907   LTPPPQ----KAAPQGKSKSDP-----------LKKKTDRAPPSPPCDITCLESF----- 946
             LT   +     AA   K +SDP           ++ K     P    ++   E       
Sbjct: 19053 LTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVP 19112

Query: 947   ---RDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKE 1003
                R    + W++ D     E T   V+  + +  +  K  EA+ + V      +SN   
Sbjct: 19113 FKGRPQATVNWRK-DGQTLKETTRVNVSSSKTVTSLSIK--EASKEDVGTYELCVSNSAG 19169

Query: 1004  NMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPV 1063
             ++     +  ++  G   P  + E   C+  TI+                     W PP 
Sbjct: 19170 SITVPITIIVLDRPGPPGPIRIDE-VSCDSITIS---------------------WNPPE 19207

Query: 1064  HSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGV 1123
             + G   ++ Y V+ KE  +    W  +++ A+    +K+  L  G  Y FRV A N+ G 
Sbjct: 19208 YDGGCQISNYIVEKKETTS--TTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGK 19264

Query: 1124  GKPSDLAGPVVAE------TRPGTKEVV------------VNVDDDGVISLNFECDKMTP 1165
                S+ +  VVAE        PGT +VV            V V+D G   + +  +    
Sbjct: 19265 SSYSE-SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLE-YKE 19322

Query: 1166  KSEFSWSK 1173
             +S   WSK
Sbjct: 19323 RSSILWSK 19330



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 84/340 (24%), Positives = 135/340 (39%), Gaps = 45/340 (13%)

Query: 274   LHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYII-ESRY 332
             + AP F  + R+  V  + N  L C + G P+P V WY+    I   A+  KY I E + 
Sbjct: 24620 IQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII--ADGLKYRIQEFKG 24677

Query: 333   GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF 392
             G H L I     +D   Y+  A N  G +S  AS+ V+         + H   +   +  
Sbjct: 24678 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEV------PAKIHLPKTLEGMGA 24731

Query: 393   GVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSP 452
                  G     +I F  K D                          P I W +    +  
Sbjct: 24732 VHALRGEVVSIKIPFSGKPD--------------------------PVITWQKGQDLIDN 24765

Query: 453   SKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPA 511
             +   Q + +    +L F + + ++D G Y +  +     +Q       +  + ++   P 
Sbjct: 24766 NGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQ-------KTVELDVADVPD 24818

Query: 512   APLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPV 571
              P  VK  + ++D + ++W +PA DGGS I  Y ++KC    + W +      +  R+ V
Sbjct: 24819 PPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ--ARETRYTV 24876

Query: 572   TGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKA 611
               L    SY FRV A NK G+  PS  SEP    +   +A
Sbjct: 24877 INLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRA 24916



 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 58/224 (25%), Positives = 109/224 (48%), Gaps = 17/224 (7%)

Query: 157   ERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTA 216
             E +K++AA   +++++  E  IT + Q++   +T A  ++ +++ S    Q    + + A
Sbjct: 26701 EEVKKSAATSLEKSIVHEE--ITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIA 26758

Query: 217   SRQSVV----SKQATSALQQEETSEKKSRKVVIREKAER-----LSLRKTLEETET--YH 265
                 V       + T++ +         + + I++ + R       + KT E      Y 
Sbjct: 26759 GATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYD 26818

Query: 266   AKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGK 325
               L+++ L  AP FI +PRS  + E +NV   C I+G P P + W+KN +PI++ +N   
Sbjct: 26819 LTLSKE-LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVS- 26876

Query: 326   YIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
               I     +++LEI      D+ +Y   A N +G+ SA AS++V
Sbjct: 26877 --ISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 104/533 (19%), Positives = 203/533 (38%), Gaps = 97/533 (18%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            F C+  T  ++  W ++  +  DS +  +  K     +  +D  +DD   Y+  +T+  G
Sbjct: 6354 FNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 6413

Query: 1218 ----IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
                 A++ +++EE+L+ +            P+K    +E +EK  V FW +  +L  N 
Sbjct: 6414 ENVKSAANLIVEEEDLRIV-----------EPLKD---IETMEKKSVTFWCKVNRL--NV 6457

Query: 1274 KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1333
             + +  N +E+    +    +D+   ++ +  +     DEG Y       K+     ++ 
Sbjct: 6458 TLKWTKNGEEVPFDNRVSYRVDKYKHMLTI--KDCGFPDEGEYIVTAGQDKSVAELLII- 6514

Query: 1334 VGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECN-VLLKCKVANIKKETHIVWY 1392
                                 +    FVE+L  +   E +  +  C+++  +++ ++ WY
Sbjct: 6515 ---------------------EAPTEFVEHLEDQTVTEFDDAVFSCQLS--REKANVKWY 6551

Query: 1393 KDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKE-- 1450
            ++ REI   +K+ F+             KD  I+ +I+KD R  D+       E  K   
Sbjct: 6552 RNGREIKEGKKYKFE-------------KDGSIHRLIIKDCRLDDECEYACGVEDRKSRA 6598

Query: 1451 --LMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTG 1508
               + E+  +I     D+     A G  +        + ++V W  N   +   D+ +  
Sbjct: 6599 RLFVEEIPVEIIRPPQDIL---EAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMM 6655

Query: 1509 VTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAE 1568
              G+   LQI +  P D+G+Y     D                 EA A+ +      I  
Sbjct: 6656 SEGKIHRLQICDIKPRDQGEYRFIAKD----------------KEARAKLELAAAPKIKT 6699

Query: 1569 KNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRT 1628
             ++  V         +  GK L +       P  E  W K  + L++     +   A +T
Sbjct: 6700 ADQDLV---------VDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK---TIDTTAEQT 6747

Query: 1629 AYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVF-IPEEEARMAALESLKG 1680
            + F I      D G+Y +V++NK+G       + V  +P     +   E+  G
Sbjct: 6748 S-FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6799



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 67/296 (22%), Positives = 117/296 (39%), Gaps = 27/296 (9%)

Query: 1378  CKVANIKKETHIVWYKDEREISVDEKHD--FKDGICTLLITEFSKKDAGIYEVILKDDRG 1435
             CK+ N  + T + WY   R++   EK++  ++DG+  L + + +K D G Y   + +D G
Sbjct: 25284 CKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYG 25343

Query: 1436  KDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHN 1495
             +D S  +L  +  +E+    C++     T  KI+   + ++L      +   L    ++ 
Sbjct: 25344 EDSSYAELFVKGVREVYDYYCRR-----TMKKIKRRTDTMRLLERPPEFTLPLYNKTAYV 25398

Query: 1496  GSAIRYSDRVKTGVTGEQIWLQINE---PTPNDKGKYVMELFDGKTGHQKTVDLSGQAYD 1552
             G  +R+   +         W +  +   P  NDK KY  E    K  +Q T++      D
Sbjct: 25399 GENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDK-KYTFE--SDKGLYQLTINSVTTDDD 25455

Query: 1553  EAYAEFQRLKQAAIAEKNRARVLGGLPDV--------------VTIQEGKALNLTCNVWG 1598
               Y    R K    + K +  V    P                   QEG+++     V G
Sbjct: 25456 AEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 25515

Query: 1599  DPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGS 1654
              PPP + W K+ + L+   +  +  E        I      D+G Y +   N  GS
Sbjct: 25516 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGS 25571



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 102/489 (20%), Positives = 180/489 (36%), Gaps = 79/489 (16%)

Query: 1165 PKSEFSWSKDYVSTEDSPRLE-VESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            P  E  W K+ V  E S R+     + N  ++  +D+  +D         +  G  SS+ 
Sbjct: 2059 PDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHA 2118

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
                + K+L+  + E +      K  +A             + E      KV +  +  E
Sbjct: 2119 FLLVQAKQLITFTQELQDVVAKEKDTMAT-----------FECETSEPFVKVKWYKDGME 2167

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQK 1343
            + EG KY+MH DR    + +      D ++ +    ++D      + +++ G V + +++
Sbjct: 2168 VHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVL-VEDENVKTTAKLIVEGAVVEFVKE 2226

Query: 1344 EAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVA--NIKKETHIVWYKDEREISVD 1401
              + +  E                 +GE    L+C V+  NI+ +    WY ++ E+  +
Sbjct: 2227 LQDIEVPE---------------SYSGE----LECIVSPENIEGK----WYHNDVELKSN 2263

Query: 1402 EKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKI 1459
             K+    + G   L + + +K+D G Y  ++  D  K   +LK+       L        
Sbjct: 2264 GKYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTCKLKMKPRPIAILQ------- 2314

Query: 1460 ALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN 1519
                  L  Q   EG  +   V   +E ++  W  +G  ++ SDRV   +  +   L I 
Sbjct: 2315 -----GLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIE 2369

Query: 1520 EPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLP 1579
            + T  D G Y   +          + LS       Y+                 V+  L 
Sbjct: 2370 DMTKEDAGNYSFTI--------PALGLSTSGRVSVYS---------------VDVITPLK 2406

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
            DV  I+  KA+ L C V       V W  N++ +  DD        G      IN    +
Sbjct: 2407 DVNVIEGTKAV-LECKVSVPDVTSVKWYLNDEQIKPDDRVQ-AIVKGTKQRLVINRTHAS 2464

Query: 1640 DSGKYGLVV 1648
            D G Y L+V
Sbjct: 2465 DEGPYKLIV 2473



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 121/559 (21%), Positives = 206/559 (36%), Gaps = 117/559 (20%)

Query: 1168  EFSWSKDYVSTEDSPRLEVESKGNKT-KMTFKDLGMDDLGIYSCDVTDTDGIASSYL--- 1223
             E +W KD    +++   +     + T ++   +L   D G Y C+++   G + + L   
Sbjct: 26443 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26502

Query: 1224  -------------------IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWM 1264
                                 D++  +  +    E K P       + V  L+   V    
Sbjct: 26503 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDS 26562

Query: 1265  QAE---KLSGNAKVNYIFNE--KEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQ 1319
              A+   K +G  +   I+ +  K I +G KYK+  D+    +E+   K    D G YT  
Sbjct: 26563 VAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEI--HKTDTSDSGLYTCT 26620

Query: 1320  LQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCK 1379
             +++   +  S+  L      K  K+ E Q+              +S + T E   +   K
Sbjct: 26621 VKNSAGSVSSSCKLT----IKAIKDTEAQK--------------VSTQKTSE---ITPQK 26659

Query: 1380  VANIKKETHIVWYKDER----EISVDEKHDFKDGICTLLITEFSKKDAG-------IYEV 1428
              A +++E      + E     E    EK   K+    +LI+E  KK A        ++E 
Sbjct: 26660 KAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEE 26719

Query: 1429  ILKDDRGKDKSRLKLVDEAFKELMME------VCKKIALSATDLKIQSTAEGIQLYSFVT 1482
             I K  +  ++ R     +AF   M        V K     ATD+K               
Sbjct: 26720 ITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVK--------------- 26764

Query: 1483  YYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKG--KYVMELFDGKTGH 1540
                      W  NG  +  S+  + GV+G    L I + +  D+G    + +  +G    
Sbjct: 26765 ---------WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKC 26815

Query: 1541  QKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDP 1600
             Q  + LS +  D           A I++          P    I EG+ +  TC + G+P
Sbjct: 26816 QYDLTLSKELSDAP---------AFISQ----------PRSQNINEGQNVLFTCEISGEP 26856

Query: 1601  PPEVSWLKNEKALASDDHCNLKFEAGRTAY-FTINGVSTADSGKYGLVVKNKYGSETSDF 1659
              PE+ W KN   ++     N+     R  Y   I   S +DSGKY +  KN  G  ++  
Sbjct: 26857 SPEIEWFKNNLPISISS--NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 26914

Query: 1660  TVSVF-IPEEEARMAALES 1677
             ++ V  + EE +R   L +
Sbjct: 26915 SLMVLPLVEEPSREVVLRT 26933



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 91/360 (25%), Positives = 148/360 (41%), Gaps = 39/360 (10%)

Query: 175  EEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEE 234
            E  I  S  +T  K+ +A+  S+A K + + K  T     T  R               +
Sbjct: 785  EASIAGSAIATLQKELSAT--SSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTPD 842

Query: 235  TSEKKSRKVVIREKAERLSLRKTLEET-ETYH---AKLNEDHLLHAP-EFIIKP------ 283
            T + ++   V +E    ++     EE  E  H   AK+ E   + AP E  + P      
Sbjct: 843  TYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSG 902

Query: 284  -RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGC 342
             ++ TV E E+V L C I+G+P P VTWY+    I    +   + I  + G+  L I   
Sbjct: 903  LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSID---FQITFQSGIARLMIREA 959

Query: 343  DFEDTAQYRASAMNVKGEL--SAYASVVVKR----------YKGEFDETRFHAGASTMPL 390
              ED+ ++  SA+N  G +  S Y +V V             K   +E RF      +  
Sbjct: 960  FAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMT 1019

Query: 391  SFGVT--PYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGV 448
               +T    G       +F  K  V    EG ++  GC+V   P     +P + W ++GV
Sbjct: 1020 DTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP-----KPHVYWKKSGV 1074

Query: 449  PLSPSKWVQTLWSGE--RATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEI 506
            PL+     +  ++ +     L  S    +D G YTI VR  ++ E  ++   + +AD E+
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVR-NKHGETSASASLLEEADYEL 1133



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 63/303 (20%), Positives = 130/303 (42%), Gaps = 23/303 (7%)

Query: 1039  PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1098
             P  P +L   EV+KDS+ L W+PP+  G   +T Y V+ +E   K   +  +     K  
Sbjct: 18894 PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK--AYATITNNCTKTT 18951

Query: 1099  YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD-DDGVISLN 1157
             + ++  L+EG SY FRV A N+ G+G P++   PV     P     V  VD      ++ 
Sbjct: 18952 F-RIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIK 19010

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             +E  +    S+ +     + T+ S +    ++    + T   L   +  ++     +  G
Sbjct: 19011 WEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKG 19070

Query: 1218  IASSYLIDEEELKRLLALSHEHKFP----TVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
              +    +    + R + +    + P     V  + +L +++  KG+ +           A
Sbjct: 19071 RSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQ-----------A 19119

Query: 1274  KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD--GKATNHSTV 1331
              VN+  + + + E    ++++  +  +  + +++   ED GTY   + +  G  T   T+
Sbjct: 19120 TVNWRKDGQTLKE--TTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITI 19177

Query: 1332  VLV 1334
             +++
Sbjct: 19178 IVL 19180



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 62/233 (26%), Positives = 93/233 (39%), Gaps = 35/233 (15%)

Query: 251   RLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTW 310
             R +++K    T+T         L   PEF +   + T +  ENV+   +I   PEP VTW
Sbjct: 25365 RRTMKKIKRRTDTMRL------LERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTW 25418

Query: 311   YKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
             YK+   I    N  KY  ES  G++ L IN    +D A+Y   A N  GE S  A + V 
Sbjct: 25419 YKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 25478

Query: 371   RYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVI 430
              +    D T         P+                F      +  +EG+++    RV  
Sbjct: 25479 LHPPPTDST-------LRPM----------------FKRLLANAECQEGQSVCFEIRVSG 25515

Query: 431   TPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG-ERATLTFSHLNKEDEGLYTI 482
              P      P ++W ++G PLS    ++ +  G +   L       ED G Y +
Sbjct: 25516 IP-----PPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25563



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 110/549 (20%), Positives = 203/549 (36%), Gaps = 91/549 (16%)

Query: 1132 PVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGN 1191
            P V  T+P   + V    ++G  ++  EC+     ++  W K+      S + E+ + G 
Sbjct: 5978 PPVEFTKPLEDQTV----EEGATAV-LECEVSRENAKVKWFKNGTEILKSKKYEIVADGR 6032

Query: 1192 KTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELA 1251
              K+   D   +D+  Y+CD  D     +  ++                 P V     L 
Sbjct: 6033 VRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVP----------------PHVEFLRPLT 6076

Query: 1252 -VEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQD 1310
             +++ EK   RF  + E    NAKV +  +  EI +G KY   I     +  + + K   
Sbjct: 6077 DLQVREKEMARF--ECELSRENAKVKWFKDGAEIKKGKKY--DIISKGAVRILVINKCLL 6132

Query: 1311 EDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTG 1370
            +DE  Y+ +++  + +   TV         L++EA F +               + EV+ 
Sbjct: 6133 DDEAEYSCEVRTARTSGMLTV---------LEEEAVFTK------------NLANIEVSE 6171

Query: 1371 ECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVIL 1430
               + L C+V+  K    ++WYK + EI    +++        ++TE  K+   I    L
Sbjct: 6172 TDTIKLVCEVS--KPGAEVIWYKGDEEIIETGRYE--------ILTEGRKRILVIQNAHL 6221

Query: 1431 KDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKV 1490
             +D G    RL       K  + E+  +      +L+I    EG +     +   E   V
Sbjct: 6222 -EDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEI---LEGEKAEFVCSISKESFPV 6277

Query: 1491 NWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQA 1550
             W  +   +   D+      G++  L + + T  D G YV+ +   +     TV      
Sbjct: 6278 QWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTV------ 6331

Query: 1551 YDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNE 1610
                                + R++  L D   ++E + +   C V      +  W +NE
Sbjct: 6332 ------------------IEKLRIVVPLKD-TRVKEQQEVVFNCEV-NTEGAKAKWFRNE 6371

Query: 1611 KALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEA 1670
            +A+  D    +  +        I      D   Y + + N  G E      ++ + EE+ 
Sbjct: 6372 EAI-FDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG-ENVKSAANLIVEEEDL 6429

Query: 1671 RMAALESLK 1679
            R+  +E LK
Sbjct: 6430 RI--VEPLK 6436



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 62/235 (26%), Positives = 100/235 (42%), Gaps = 13/235 (5%)

Query: 142   SGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQSTASKQ 201
             S RQ+ V+ IT+ EEE   E + + AQR   +S   +   ++S +       +  +   +
Sbjct: 25930 SRRQREVTEITEIEEEY--EISKH-AQRESSSSASRLLRRRRSLSPTYIELMRPVSELIR 25986

Query: 202   STAS-----KQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRK 256
             S        +  T  R  T  R    S    S+ +     E+ +R  +        +  K
Sbjct: 25987 SRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALK 26046

Query: 257   TLEETETYHAKLNEDH--LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQ 314
             T + +E  +  L++    L HAP   ++ RSH V   +N +   ++   P   V WY N 
Sbjct: 26047 TQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNG 26106

Query: 315   VPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
             V +       K    +  G+ TLEI  C  +D+  YRA   N KGE S YA++ V
Sbjct: 26107 VELQ---ESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 105/531 (19%), Positives = 200/531 (37%), Gaps = 98/531 (18%)

Query: 1147 NVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLG 1206
            N++     + +FEC+         W K+ V  E S + ++  +G   ++   +   +D  
Sbjct: 2844 NIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSA 2903

Query: 1207 IYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQA 1266
             Y+  V   D ++++  +    +  +L   +  +  T+  +    V +  +G    W++ 
Sbjct: 2904 EYTF-VCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFE----VTVNYEGISYKWLK- 2957

Query: 1267 EKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKAT 1326
                         N  EI    K +M   + T  + +    +   D   YTF    GKAT
Sbjct: 2958 -------------NGVEIKSTDKCQMRTKKLTHSLNI--RNVHFGDAADYTFVA--GKAT 3000

Query: 1327 NHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKE 1386
            + +T+ +         +  EF++         H  +    +V  +   + +C+V+  + +
Sbjct: 3001 STATLYVEA-------RHIEFRK---------HIKDI---KVLEKKRAMFECEVS--EPD 3039

Query: 1387 THIVWYKDEREISVDEKHDFKDG--ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLV 1444
              + W KD++E+ + ++   +    +  LLI      DAG Y V+     G + S  KL 
Sbjct: 3040 ITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA----GGNVSTAKLF 3095

Query: 1445 DEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVE------DLKVNWSHNGSA 1498
             E                  D++I+S  + +Q+       VE      D+  +W  +G  
Sbjct: 3096 VEG----------------RDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIE 3139

Query: 1499 IRYS--DRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYA 1556
            I +   +R K  V      + I+E   +D G+Y      G+     T+ ++     +   
Sbjct: 3140 INFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA--GRNRSSVTLYVNAPEPPQVLQ 3197

Query: 1557 EFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD 1616
            E Q                      VT+Q GK       + G P P++SW K E+ L++ 
Sbjct: 3198 ELQP---------------------VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTG 3236

Query: 1617 DHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPE 1667
              C    +        I      D+  Y    KN YG  T+  ++SV +PE
Sbjct: 3237 FKCKFLHDGQEYTLLLIEAF-PEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 46/149 (30%), Positives = 67/149 (44%), Gaps = 9/149 (6%)

Query: 637   VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             VP PP  + V++ +R  V L+W  P   G   I  Y VEKC    E W RV      +  
Sbjct: 24816 VPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ---ARET 24872

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV-GDKLDIPKAPGKIIPSRNTDTS 754
             R+ + +L    SY FRV   N  G+ +PSE +E T+   DK        ++  +R     
Sbjct: 24873 RYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR----E 24928

Query: 755   VVVSWEESKDAKELVGYYIEASVAGSGKW 783
             V ++       KEL   Y+ A   G G++
Sbjct: 24929 VSMTKASHSSTKELYEKYMIAEDLGRGEF 24957



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 101/468 (21%), Positives = 186/468 (39%), Gaps = 77/468 (16%)

Query: 1073 YFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGP 1132
            +F D  E K K  ++  +++ A++ + +    L +   Y   VR    +G+         
Sbjct: 6101 WFKDGAEIK-KGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLT------- 6152

Query: 1133 VVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNK 1192
            V+ E    TK +  N++     ++   C+   P +E  W K      ++ R E+ ++G K
Sbjct: 6153 VLEEEAVFTKNLA-NIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRK 6211

Query: 1193 TKMTFKDLGMDDLGIYSCDVTD--TDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSEL 1250
              +  ++  ++D G Y+C +    TDG    + +  E + +   L               
Sbjct: 6212 RILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL--------------- 6256

Query: 1251 AVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQD 1310
              EILE  +  F     K S    V +  ++K +  G KY +  D    ++ +    LQD
Sbjct: 6257 --EILEGEKAEFVCSISKES--FPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQD 6312

Query: 1311 EDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTG 1370
               GTY   +   +A  H TV+    +   L+     ++QE                   
Sbjct: 6313 M--GTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQE------------------- 6351

Query: 1371 ECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIYEV 1428
               V+  C+V    +     W+++E  I    K+    KD + TL I +    D   Y V
Sbjct: 6352 ---VVFNCEVNT--EGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNV 6406

Query: 1429 ILKDDRGKD-KSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVED 1487
             L + RG++ KS   L+ E     ++E  K I             E ++  S VT++ + 
Sbjct: 6407 SLTNHRGENVKSAANLIVEEEDLRIVEPLKDI-------------ETMEKKS-VTFWCKV 6452

Query: 1488 LKVN----WSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
             ++N    W+ NG  + + +RV   V   +  L I +    D+G+Y++
Sbjct: 6453 NRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIV 6500



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 14/165 (8%)

Query: 1038  VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
             VP PP  +K S+V +DS+ L W  P   G + +T Y V+  +     ++W  + +A  + 
Sbjct: 24816 VPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVE--KCATTAERWLRVGQA--RE 24871

Query: 1098  VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN 1157
                 V  L    SY FRV A N+ G+ KPS+ + P + +     K   +N D++   +  
Sbjct: 24872 TRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE---DKTRAMNYDEEVDETRE 24928

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLE-------VESKGNKTKM 1195
                 K +  S     + Y+  ED  R E       VE+   KT M
Sbjct: 24929 VSMTKASHSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYM 24973



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 92/403 (22%), Positives = 156/403 (38%), Gaps = 48/403 (11%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            FEC+   P     W KD    + + R++++ +    ++      M D G Y+  V     
Sbjct: 3031 FECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYT--VVAGGN 3088

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQ--VRFWMQAEKLSGNAKV 1275
            ++++ L  E    R+ ++  E             V+++EK +  V F +  + +  +   
Sbjct: 3089 VSTAKLFVEGRDVRIRSIKKE-------------VQVIEKQRAVVEFEVNEDDVDAHWYK 3135

Query: 1276 NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVG 1335
            + I    ++ E  KY   ++R   I  MF+ + +  D G YTF        N S+V L  
Sbjct: 3136 DGIEINFQVQERHKYV--VERR--IHRMFISETRQSDAGEYTFVA----GRNRSSVTLYV 3187

Query: 1336 DVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDE 1395
            +  +  Q   E Q       +   F                 C V + + +  I WYK+E
Sbjct: 3188 NAPEPPQVLQELQPVTVQSGKPARF-----------------CAVISGRPQPKISWYKEE 3230

Query: 1396 REISVDEKHDF-KDGI-CTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1453
            + +S   K  F  DG   TLL+ E   +DA +Y    K+D G   +   L  E  + +  
Sbjct: 3231 QLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSP 3290

Query: 1454 EVCKKIALSA--TDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTG 1511
            +    +   A  T L+   T+EG            DLKV+W      I+ S   +     
Sbjct: 3291 DQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFE 3350

Query: 1512 EQIWLQINEPTPNDKGKYVMELFD--GKTGHQKTVDLSGQAYD 1552
            +   L+I E  P D+G Y     +  G+      + L  QA D
Sbjct: 3351 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALD 3393



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 36/116 (31%), Positives = 59/116 (50%), Gaps = 7/116 (6%)

Query: 1036 IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE--DQWRGLNEA 1093
            I +PGP   +K S++ K S  L W+PP   G TP+  Y ++ +EA  +       G N+ 
Sbjct: 8172 IGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKL 8231

Query: 1094 AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD 1149
            +       V+ L     Y FRV+A+N+ G G+  +L  PV+A+      +  V+V+
Sbjct: 8232 S-----WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8282



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 96/288 (33%)

Query: 1489  KVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY--VMELFDGKTGHQKTVDL 1546
             +V W HNG  ++ S ++    T   + L+I +   +D G Y  V   + G+     T+D+
Sbjct: 26099 EVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158

Query: 1547  SGQAYD----------------------EAYA--EFQR---------------------- 1560
             +G  Y                       EAYA   F++                      
Sbjct: 26159 TGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRE 26218

Query: 1561  ------------LKQAAIAEKN--------------RARVLGGLPDVVTIQEGKALNLTC 1594
                         +K AA+ EK+               AR+L   P  +T+ EG++   +C
Sbjct: 26219 SLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTK-PRSMTVYEGESARFSC 26277

Query: 1595  NVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAY---FTINGVSTADSGKYGLVVKNK 1651
             +  G+P P V+WL+  + L++    + + +   T Y   F I+ V  +D G Y +VV+N 
Sbjct: 26278 DTDGEPVPTVTWLRKGQVLST----SARHQVTTTKYKSTFEISSVQASDEGNYSVVVENS 26333

Query: 1652  YGSETSDFTVSV--------------FIPEEEARMAALESLKGGKKAK 1685
              G + ++FT+++               +   E R+ + E++K  K+ K
Sbjct: 26334 EGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVK 26381



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 57/235 (24%), Positives = 100/235 (42%), Gaps = 27/235 (11%)

Query: 1466  LKIQSTAEGIQLYSFVTYYVEDLK-VNWSHNGSAIRYSDRVKTGVTGEQIW-LQINEPTP 1523
             LK +++ E  +L   V   V   K V W  +G  ++ +   +   + +  + L+IN  T 
Sbjct: 26419 LKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 26478

Query: 1524  NDKGKYVMELFDGKTGHQKT-VDLSGQAY----------DEAYAEFQRLKQAAIAEKNRA 1572
             +D+G+YV E+  G+ G  KT +   GQA+           E     Q+  ++ +  K   
Sbjct: 26479 SDQGEYVCEI-SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP 26537

Query: 1573  R----------VLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLK 1622
             +          ++ GL D  T+             G+P P   W K+ KA+       L 
Sbjct: 26538 KAPEPISSKPVIVTGLQD-TTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS 26596

Query: 1623  FEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV-FIPEEEARMAALE 1676
              + G   +  I+   T+DSG Y   VKN  GS +S   +++  I + EA+  + +
Sbjct: 26597 EDKG-GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 26650



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 93/428 (21%), Positives = 159/428 (37%), Gaps = 58/428 (13%)

Query: 1039  PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1098
             PGP   L  S V ++   L W  P   G   +T Y V+ +E       W  +        
Sbjct: 22836 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLN--WVIVEGECPTLS 22893

Query: 1099  YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA--------------ETRPGTKEV 1144
             Y+  R +K    Y+FRVRA+N+ G G P + + P+VA              E   G + +
Sbjct: 22894 YVVTRLIKNN-EYIFRVRAVNKYGPGVPVE-SEPIVARNSFTIPSPPGIPEEVGTGKEHI 22951

Query: 1145  VVN----VDDDGVISLNFECDKMTPKSEFSWS---KDYVSTEDSPRLEVESKGNKTKMTF 1197
             ++       D G    N+  DK   KS   W+   KDYV  +            + K+T 
Sbjct: 22952 IIQWTKPESDGGNEISNYLVDKREKKS-LRWTRVNKDYVVYD-----------TRLKVTS 22999

Query: 1198  KDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEK 1257
                G D    Y   VT  +   +S   +  E    ++   E  +   P  +   V+  + 
Sbjct: 23000 LMEGCD----YQFRVTAVNAAGNS---EPSEASNFISC-REPSYTPGPPSAPRVVDTTKH 23051

Query: 1258  GQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
                  W +     G   V Y+   +E      Y++H +      E  +  L+   +  Y+
Sbjct: 23052 SISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK--YS 23109

Query: 1318  FQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLK 1377
             F++           V V  + +  +  AE +  E I        + L   VT      L+
Sbjct: 23110 FRV---------AAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLR 23160

Query: 1378  CKVANIKKETHIV-WYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGK 1436
               V+   +   ++ W K   +++     D  +    L++ + ++ DAG Y +  ++  GK
Sbjct: 23161 LMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGK 23220

Query: 1437  DKSRLKLV 1444
              KS   LV
Sbjct: 23221 -KSATVLV 23227



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 100/495 (20%), Positives = 186/495 (37%), Gaps = 92/495 (18%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            FEC+     ++  W KD    +   + ++ SKG    +      +DD   YSC+V     
Sbjct: 6088 FECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTART 6147

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
                 +++EE                V  K+   +E+ E   ++   +  K    A+V +
Sbjct: 6148 SGMLTVLEEE---------------AVFTKNLANIEVSETDTIKLVCEVSK--PGAEVIW 6190

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQL----QDGKATNHSTVVL 1333
               ++EI E  +Y++  +    I  + ++    ED G Y  +L     DGK   H     
Sbjct: 6191 YKGDEEIIETGRYEILTEGRKRI--LVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAA- 6247

Query: 1334 VGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYK 1393
                             E+I K  P  +E L  E          C ++  K+   + W +
Sbjct: 6248 -----------------EFISK--PQNLEILEGE-----KAEFVCSIS--KESFPVQWKR 6281

Query: 1394 DEREISVDEKHD-FKDG-ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKEL 1451
            D++ +   +K+D   DG    L++ + + +D G Y V++   R    + L ++++     
Sbjct: 6282 DDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARA--AAHLTVIEKL---- 6335

Query: 1452 MMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTG 1511
                  +I +   D +++   E +      T   E  K  W  N  AI  S +       
Sbjct: 6336 ------RIVVPLKDTRVKEQQEVVFNCEVNT---EGAKAKWFRNEEAIFDSSKYIILQKD 6386

Query: 1512 EQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAA--IAEK 1569
                L+I +   +D+  Y + L    T H+                 + +K AA  I E+
Sbjct: 6387 LVYTLRIRDAHLDDQANYNVSL----TNHRG----------------ENVKSAANLIVEE 6426

Query: 1570 NRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTA 1629
               R++  L D+ T+ E K++   C V       + W KN + +  D+  + + +  +  
Sbjct: 6427 EDLRIVEPLKDIETM-EKKSVTFWCKV-NRLNVTLKWTKNGEEVPFDNRVSYRVDKYK-H 6483

Query: 1630 YFTINGVSTADSGKY 1644
              TI      D G+Y
Sbjct: 6484 MLTIKDCGFPDEGEY 6498



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             +P+ +TI+ GK L +  +V+G P P   W K E  + +  H  +  +A  ++   I  V+
Sbjct: 12599 MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV-HKADSSSILIIKDVT 12657

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG Y L  +N  G++T    V V
Sbjct: 12658 RKDSGYYSLTAENSSGTDTQKIKVVV 12683



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 44/192 (22%), Positives = 83/192 (43%), Gaps = 30/192 (15%)

Query: 180   TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
             T   + +S + T+  ++++S +   S Q T +R+S +S +   S +  SA  +E++ E  
Sbjct: 26186 TEAYAVSSFKKTSEMEASSSVREVKS-QMTETRESLSSYEHSASAEMKSAALEEKSLE-- 26242

Query: 240   SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
                    EK+    ++ TL                 A   + KPRS TV+E E+ +  C 
Sbjct: 26243 -------EKSTTRKIKTTL-----------------AARILTKPRSMTVYEGESARFSCD 26278

Query: 300   IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
               G P P VTW +    ++  A   ++ + +     T EI+     D   Y     N +G
Sbjct: 26279 TDGEPVPTVTWLRKGQVLSTSA---RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEG 26335

Query: 360   ELSAYASVVVKR 371
             +  A  ++ +++
Sbjct: 26336 KQEAEFTLTIQK 26347



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 32/84 (38%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D +TI+ G+A  LT    G P P+VSW K+E  +  DD  ++K      A   I     +
Sbjct: 10521 DKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK-AKRS 10579

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             DSGKY +VV+N  GS      V+V
Sbjct: 10580 DSGKYCVVVENSTGSRKGFCQVNV 10603



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 47/166 (28%), Positives = 72/166 (43%), Gaps = 9/166 (5%)

Query: 1503  DRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQ--- 1559
             +R      G+  WL+ N    +D    V  L +G T   + +  +        +E     
Sbjct: 22671 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22730

Query: 1560  --RLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDD 1617
               R + A    +  AR+ G   D+VTI+ G  L L   V G P P++ W K +K L   +
Sbjct: 22731 TCRDEYAPPKAELDARLHG---DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCE 22787

Query: 1618  HCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               +L++  G+ A   I     +DSGKY L VKN  G++     V V
Sbjct: 22788 KVSLQY-TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV 22832



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 78/375 (20%), Positives = 132/375 (35%), Gaps = 84/375 (22%)

Query: 184  STASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKV 243
            +T +K+    K++         ++S   R     R      +A +A++ +   + +S + 
Sbjct: 1924 TTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEE 1983

Query: 244  VIREKAERLSLRKTLEETETYHAKLNEDHLL----------------HAPEFIIKPRSHT 287
            ++R+  + L L  T E TE     L E+  +                 AP+   + +S T
Sbjct: 1984 LLRKTKDEL-LHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQT 2042

Query: 288  VWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDT 347
            V +  +      + G P+P   WYKN V I        Y  E    +  L I     ED+
Sbjct: 2043 VGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPED--NVCELVIRDVTAEDS 2100

Query: 348  AQYRASAMNVKGELSAYASVVVKRYK-------------GEFDETRFHAGASTMPLSFGV 394
            A     A+N+ GE S++A ++V+  +              E D        ++ P    V
Sbjct: 2101 ASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPF---V 2157

Query: 395  TPYGYASRFEIHFDDKFDVSFGR-----------------------EGETMSLGCRVVIT 431
                Y    E+H  DK+ +   R                       E E +    ++++ 
Sbjct: 2158 KVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVE 2217

Query: 432  PEIKHFQPEIQ------------------------WYRNGVPL-SPSKWVQTLWSGERAT 466
              +  F  E+Q                        WY N V L S  K+  T   G R  
Sbjct: 2218 GAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRG-RQN 2276

Query: 467  LTFSHLNKEDEGLYT 481
            LT   + KED+G Y+
Sbjct: 2277 LTVKDVTKEDQGEYS 2291



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 59/299 (19%), Positives = 114/299 (38%), Gaps = 36/299 (12%)

Query: 1373  NVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDG--ICTLLITEFSKKDAGIYEVIL 1430
             NVL  C+++  +    I W+K+   IS+           + +L I   S  D+G Y +  
Sbjct: 26845 NVLFTCEISG-EPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKA 26903

Query: 1431  KDDRGKDKSR-----LKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYV 1485
             K+ RG+  +      L LV+E  +E+++          T L+   +++ +Q+ +      
Sbjct: 26904 KNFRGQCSATASLMVLPLVEEPSREVVLRTS-----GDTSLQGSFSSQSVQMSAS----- 26953

Query: 1486  EDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVD 1545
                        S   +S    + +T  +      +   + +  +V        G      
Sbjct: 26954 -------KQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQ 27006

Query: 1546  LSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVS 1605
             L             ++ +A I  +     +  LP  ++I EGK L + C   G+P PEV+
Sbjct: 27007 LESST--------SKMLKAGI--RGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVT 27056

Query: 1606  WLKNEKALASDDHCNLKFE-AGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
             W    + + S +      E         I  V   D G Y L + N++GS+++   + +
Sbjct: 27057 WSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 20/157 (12%)

Query: 217  SRQS-VVSKQATSALQQEETSEK---KSRKVVIREKAERLSLRKTLEETETYHAKLNEDH 272
            SR S +++ +AT+    + TS     K  K ++ E+++    RK L+  E      +E  
Sbjct: 1723 SRDSGIITCRATNKYGTDHTSATLIVKDEKSLV-EESQLPEGRKGLQRIEELERMAHEGA 1781

Query: 273  LL---------HAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANP 323
            L            P+ ++ P    V E E  +  C + G+P+P+V WY N   I      
Sbjct: 1782 LTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKR- 1840

Query: 324  GKYIIESRY-GMHTLEINGCDFEDTAQYRASAMNVKG 359
                   RY G+H L+I  C   DT + + +A N +G
Sbjct: 1841 ----FRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEG 1873



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 93/463 (20%), Positives = 166/463 (35%), Gaps = 72/463 (15%)

Query: 1114 RVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSK 1173
            RV A+  +   K + L G        G  +    V+ D VI    +C+     +   W K
Sbjct: 5694 RVEAMGMSSEAKLTVLEGDPYFT---GKLQDYTGVEKDEVI---LQCEISKADAPVKWFK 5747

Query: 1174 DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLL 1233
            D    + S    +++ G K  +  K     D+G Y+CD   TD  +    I++ E+K + 
Sbjct: 5748 DGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD-CGTDKTSGKLDIEDREIKLVR 5806

Query: 1234 ALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMH 1293
             L               +VE++E    RF  + E    +   N+    + + + P     
Sbjct: 5807 PLH--------------SVEVMETETARF--ETEISEDDIHANWKLKGEALLQTP--DCE 5848

Query: 1294 IDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTV-VLVGDVFKKLQKEAEFQRQEW 1352
            I     I  + +   + +  G   FQ  + K++ H  V   V  + + L+          
Sbjct: 5849 IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVT------- 5901

Query: 1353 IRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICT 1412
                           VT        C+++   ++  + WY   +++   +K         
Sbjct: 5902 ---------------VTAGETATFDCELS--YEDIPVEWYLKGKKLEPSDK--------- 5935

Query: 1413 LLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSAT-DLKIQST 1471
                   + +  ++ + L+D + +D   ++L  + FK       K+  +  T  L+ Q+ 
Sbjct: 5936 ----VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTV 5991

Query: 1472 AEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
             EG           E+ KV W  NG+ I  S + +    G    L I++ TP D   Y  
Sbjct: 5992 EEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 6051

Query: 1532 ELFDGKTGHQKTVDLSGQAYDEAYAEFQR-LKQAAIAEKNRAR 1573
            +  D KT     V          + EF R L    + EK  AR
Sbjct: 6052 DAKDFKTSCNLNV-------VPPHVEFLRPLTDLQVREKEMAR 6087



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 96/436 (22%), Positives = 168/436 (38%), Gaps = 62/436 (14%)

Query: 1100 LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFE 1159
            L +R +    S    V+AIN AG             +    T+E+   V  +      FE
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFE 2149

Query: 1160 CDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIA 1219
            C+   P  +  W KD +   +  +  + S      ++   +   D   YSC + + + + 
Sbjct: 2150 CETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVK 2209

Query: 1220 SSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILE--KGQVRFWMQAEKLSGNAKVNY 1277
            ++         +L+      +F    VK    +E+ E   G++   +  E + G     +
Sbjct: 2210 TT--------AKLIVEGAVVEF----VKELQDIEVPESYSGELECIVSPENIEG----KW 2253

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDV 1337
              N+ E+    KY   I    G   + ++ +  ED+G Y+F + DGK T           
Sbjct: 2254 YHNDVELKSNGKYT--ITSRRGRQNLTVKDVTKEDQGEYSFVI-DGKKTT---------- 2300

Query: 1338 FKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVL-LKCKVANIKKETHIVWYKDER 1396
              KL+          ++ +    ++ LS +   E +++ L+ KV+   +    VW KD +
Sbjct: 2301 -CKLK----------MKPRPIAILQGLSDQKVCEGDIVQLEVKVS--LESVEGVWMKDGQ 2347

Query: 1397 EIS-VDEKHDFKDGIC-TLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMME 1454
            E+   D  H   D     LLI + +K+DAG Y   +         R+ +         ++
Sbjct: 2348 EVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-------VD 2400

Query: 1455 VCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDL-KVNWSHNGSAIRYSDRVKTGVTGEQ 1513
            V        T LK  +  EG +        V D+  V W  N   I+  DRV+  V G +
Sbjct: 2401 V-------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTK 2453

Query: 1514 IWLQINEPTPNDKGKY 1529
              L IN    +D+G Y
Sbjct: 2454 QRLVINRTHASDEGPY 2469



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 115/564 (20%), Positives = 203/564 (35%), Gaps = 88/564 (15%)

Query: 1090 LNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD 1149
            L E   + + ++   L++  +Y  R+ +    G  K  +LA   ++  +P   E++    
Sbjct: 6206 LTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFIS--KPQNLEILEGEK 6263

Query: 1150 DDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYS 1209
             + V S++ E   +       W +D  + E   + +V + G K  +  KD  + D+G Y 
Sbjct: 6264 AEFVCSISKESFPV------QWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYV 6317

Query: 1210 CDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKL 1269
              V      A   +I++  +              VP+K      + E+ +V F    E  
Sbjct: 6318 VMVGAARAAAHLTVIEKLRI-------------VVPLKD---TRVKEQQEVVF--NCEVN 6359

Query: 1270 SGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHS 1329
            +  AK  +  NE+ IF+  KY   I +   +  + +     +D+  Y   L + +  N  
Sbjct: 6360 TEGAKAKWFRNEEAIFDSSKYI--ILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVK 6417

Query: 1330 TVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHI 1389
            +   +    + L+     +  E + K+   F     W      NV LK            
Sbjct: 6418 SAANLIVEEEDLRIVEPLKDIETMEKKSVTF-----WCKVNRLNVTLK------------ 6460

Query: 1390 VWYKDEREISVDEKHDFKDGICTLLIT--EFSKKDAGIYEVILKDDRGKDKSRLKLVDEA 1447
             W K+  E+  D +  ++      ++T  +    D G Y V      G+DKS  +L    
Sbjct: 6461 -WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTA----GQDKSVAEL---- 6511

Query: 1448 FKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKT 1507
               L++E   +      D   Q+  E            E   V W  NG  I+   + K 
Sbjct: 6512 ---LIIEAPTEFVEHLED---QTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKF 6565

Query: 1508 GVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIA 1567
               G    L I +   +D+ +Y   + D K+  +  V       +E   E  R  Q  + 
Sbjct: 6566 EKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFV-------EEIPVEIIRPPQDILE 6618

Query: 1568 EKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGR 1627
                        DVV + E   LN           EV WL+N   +   D   +  E G+
Sbjct: 6619 APG--------ADVVFLAE---LN-------KDKVEVQWLRNNMVVVQGDKHQMMSE-GK 6659

Query: 1628 TAYFTINGVSTADSGKYGLVVKNK 1651
                 I  +   D G+Y  + K+K
Sbjct: 6660 IHRLQICDIKPRDQGEYRFIAKDK 6683



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 44/200 (22%), Positives = 83/200 (41%), Gaps = 11/200 (5%)

Query: 1484  YVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKT 1543
             Y +  +V W      +  S++ +         L + + T  D G Y  ++ +        
Sbjct: 25289 YDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSY 25348

Query: 1544  VDLSGQAYDEAYAEFQRLKQAAIAEK-NRARVLGGLPDVV------TIQEGKALNLTCNV 1596
              +L  +   E Y  + R     I  + +  R+L   P+        T   G+ +     +
Sbjct: 25349 AELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTI 25408

Query: 1597  WGDPPPEVSWLKN-EKALASDDHCNLKFEAGRTAY-FTINGVSTADSGKYGLVVKNKYGS 1654
                P P V+W K+ +K    D+     FE+ +  Y  TIN V+T D  +Y +V +NKYG 
Sbjct: 25409 TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE 25468

Query: 1655  ET--SDFTVSVFIPEEEARM 1672
             ++  +  TV++  P  ++ +
Sbjct: 25469 DSCKAKLTVTLHPPPTDSTL 25488



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 49/207 (23%), Positives = 79/207 (38%), Gaps = 35/207 (16%)

Query: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
           AP F    +S  V E         I+G+P P V+W+++   I+    PG  I  S  G  
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSD-GRA 63

Query: 336 TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVT 395
            L I      ++ +Y   A N  G+ ++ A ++VK              A T P      
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK--------------AETAP------ 103

Query: 396 PYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKW 455
                     +F  +      R+G  + L  RV   P      P +++YR+G  +  S  
Sbjct: 104 ---------PNFVQRLQSMTVRQGSQVRLQVRVTGIP-----TPVVKFYRDGAEIQSSLD 149

Query: 456 VQTLWSGERATLTFSHLNKEDEGLYTI 482
            Q    G+  +L  +    ED G Y++
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSV 176



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 2/90 (2%)

Query: 1575  LGGLPDVVTI-QEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTI 1633
             L GLPD+  + +E     L   + G P P VSW K E  LA+D   +++  A  T    +
Sbjct: 13679 LKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTT-LIV 13737

Query: 1634  NGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
                  +D+GKY + +KN  G++    ++ V
Sbjct: 13738 YDCQKSDAGKYTITLKNVAGTKEGTISIKV 13767



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 112/499 (22%), Positives = 178/499 (35%), Gaps = 92/499 (18%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            FEC+       F W K         R E+   G K  M  K    +D   Y  +  D   
Sbjct: 5554 FECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH- 5612

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
             +   +I+   LK L            P+K    V   EK    F    E    N +V +
Sbjct: 5613 TSGKLIIEGIRLKFL-----------TPLKD---VTAKEKESAVF--TVELSHDNIRVKW 5656

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDV 1337
              N++ +       M  +  T  I    + L  +D      +   G ++     VL GD 
Sbjct: 5657 FKNDQRLHTTRSVSMQDEGKTHSIT--FKDLSIDDTSQIRVEAM-GMSSEAKLTVLEGDP 5713

Query: 1338 F--KKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDE 1395
            +   KLQ     ++ E                      V+L+C+++  K +  + W+KD 
Sbjct: 5714 YFTGKLQDYTGVEKDE----------------------VILQCEIS--KADAPVKWFKDG 5749

Query: 1396 REISVDEKHDFK-DGICTLLITEFS-KKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1453
            +EI   +    K DG   +LI + + K D G Y      D G DK+  KL D   +E+  
Sbjct: 5750 KEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKL-DIEDREI-- 5802

Query: 1454 EVCKKIALSATDLKIQSTAEGIQLYSFVTYYVE-DLKVNWSHNGSAIRYSDRVKTGVTGE 1512
                K+      +++  T    +   F T   E D+  NW   G A+             
Sbjct: 5803 ----KLVRPLHSVEVMET----ETARFETEISEDDIHANWKLKGEAL------------- 5841

Query: 1513 QIWLQINEPTPNDKGK-YVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR 1571
               LQ  +    ++GK + + L + +      VD   QA +   +   R+K   I     
Sbjct: 5842 ---LQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANVKSSAHLRVKPRVIG---- 5892

Query: 1572 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYF 1631
              +L  L D VT+  G+     C +  +  P V W    K L   D    + E G+    
Sbjct: 5893 --LLRPLKD-VTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSE-GKVHTL 5947

Query: 1632 TINGVSTADSGKYGLVVKN 1650
            T+  V   D+G+  L  K+
Sbjct: 5948 TLRDVKLEDAGEVQLTAKD 5966



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 2/95 (2%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             V  + G+ + +     G PPP V+W K+EK L SD   +++     ++  TI  V+  D+
Sbjct: 20976 VIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDT 21034

Query: 1642  GKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALE 1676
             GKY L ++N  G E    TVSV + +  A    L+
Sbjct: 21035 GKYILTIENGVG-EPKSSTVSVKVLDTPAACQKLQ 21068



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 34/122 (27%), Positives = 61/122 (50%), Gaps = 7/122 (5%)

Query: 1544  VDLSGQA-YDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPP 1602
             V++ G + Y E+ AE + +++  I +   A     L   VTI+ G +L L  +V G PPP
Sbjct: 23115 VNVKGMSEYSESIAEIEPVERIEIPDLELA---DDLKKTVTIRAGASLRLMVSVSGRPPP 23171

Query: 1603  EVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVS 1662
              ++W K    LAS    +        +   ++ V+  D+GKY +  +N+ G +++   V 
Sbjct: 23172 VITWSKQGIDLASRAIID---TTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 23228

Query: 1663  VF 1664
             V+
Sbjct: 23229 VY 23230



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 152/790 (19%), Positives = 286/790 (36%), Gaps = 153/790 (19%)

Query: 997  KISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLV 1056
            KIS  K    Y+  +A   +A L     +S     ++ T +V  P  ++K SE R     
Sbjct: 774  KISVPKTEHGYEASIAGSAIATL--QKELSATSSAQKITKSVKAP--TVKPSETR----- 824

Query: 1057 LQWKPPVHSGRTPVTGY-FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRV 1115
                  V +  TP+  + F D  +    E       E  +      VR  +  V +    
Sbjct: 825  ------VRAEPTPLPQFPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREA 878

Query: 1116 RAINQAGVGKPSDLAGPVVAETR-PGTKEVVVNVDDDGVISLNFECD-KMTPKSEFSWSK 1173
            +    A V  P ++  PV   T   G K V V   +    S+  EC     P    +W +
Sbjct: 879  KVTETARVPAPVEI--PVTPPTLVSGLKNVTVIEGE----SVTLECHISGYPSPTVTWYR 932

Query: 1174 DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS--YL---IDEE- 1227
            +    E S   ++  +    ++  ++   +D G ++C   +  G  S+  YL   + EE 
Sbjct: 933  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF 992

Query: 1228 -------------ELKRLL----------ALSHEHKFPTVP-----VKSELAVEILEKGQ 1259
                         E KR +          +L+ E   P  P     +   +  +++E G 
Sbjct: 993  EKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGS 1052

Query: 1260 VRFWMQAEKLSGNAKVNYIFNEKEI--FEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
            V F  Q   + GN K +  + +  +    G +YK+  ++ TG  ++ +     +D G YT
Sbjct: 1053 VVFGCQ---VGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYT 1109

Query: 1318 FQLQDGKATNHSTVVLVGD----VFKKLQKEAEFQRQEWIRKQGPHFVE------YLSWE 1367
              +++      ++  L+ +    +  K Q+E  +Q Q     Q P   E      Y  +E
Sbjct: 1110 IVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYE 1169

Query: 1368 VTGECN-VLLKCKVANIKKETHIV-WYKDEREISVDEKHDFKDGICTLLITEFSKKDAGI 1425
               E    L++ K+A   K+T +V  Y +++E  +     F++ +   +     K     
Sbjct: 1170 KEYEKEQALIRKKMA---KDTVVVRTYVEDQEFHISS---FEERLIKEIEYRIIKTTL-- 1221

Query: 1426 YEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQS----TAEGIQLYSFV 1481
             E +L++D G++K  + + +    E           S  D +I++       G+  +  +
Sbjct: 1222 -EELLEED-GEEKMAVDISESEAVE-----------SGFDSRIKNYRILEGMGVTFHCKM 1268

Query: 1482 TYYVEDLKVNWSHNGSAIRYSDRVKTGVTGE-QIWLQINEPTPNDKGKYVM--------E 1532
            + Y    K+ W  +G  I++ +R +     + +  L+I    P D+G Y           
Sbjct: 1269 SGYPLP-KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNA 1327

Query: 1533 LFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR--------------------- 1571
            +  GK   +    L    Y        R++  +    +R                     
Sbjct: 1328 ICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMS 1387

Query: 1572 -ARVLGGL---------------------PDVVTIQEGKALNLTCNVWGDPPPEVSWLKN 1609
             AR+  G                      P      EG+       V G P PE  W  +
Sbjct: 1388 PARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHD 1447

Query: 1610 EKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEE 1669
             + + +D    +  +   T    I   + +DSG++ +V +N+ G  +    ++V   E +
Sbjct: 1448 GQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQ 1507

Query: 1670 ARMAALESLK 1679
             +   +E LK
Sbjct: 1508 VKPMFVEKLK 1517



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 41/205 (20%), Positives = 77/205 (37%), Gaps = 33/205 (16%)

Query: 1358  PHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFK---DGICTLL 1414
             P   ++L  E + E   L     +++ +   + WYKD +++  +    F    DG   L 
Sbjct: 26413 PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 26472

Query: 1415  ITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTA-- 1472
             I   ++ D G Y   +  + G  K+ L+ + +AFK +  +V K      +D K   +   
Sbjct: 26473 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVT 26532

Query: 1473  --------EGIQLYSFVTYYVEDLKVN--------------------WSHNGSAIRYSDR 1504
                     E I     +   ++D  V+                    W+ +G AI    +
Sbjct: 26533 RKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGK 26592

Query: 1505  VKTGVTGEQIWLQINEPTPNDKGKY 1529
              K        +L+I++   +D G Y
Sbjct: 26593 YKLSEDKGGFFLEIHKTDTSDSGLY 26617



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 64/306 (20%), Positives = 122/306 (39%), Gaps = 34/306 (11%)

Query: 184   STASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKV 243
             S++ K T  + + T +++ +  K S  + Q  A  Q  +S++A  + + + +  K   K+
Sbjct: 26629 SSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKL 26688

Query: 244   VIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGW 303
              ++E+A ++ +    EE +   A   E  ++H  E I K    T    E V+ H  I   
Sbjct: 26689 ALKEEASKVLIS---EEVKKSAATSLEKSIVH--EEITK----TSQASEEVRTHAEIKA- 26738

Query: 304   PEPRVTWYKNQVPINVHANPGKYIIESRYGMHT---LEINGCDFEDTAQYRASAMNVKGE 360
                    +  Q+ IN      + ++++     T     +NG +  ++ +YR         
Sbjct: 26739 -------FSTQMSIN---EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYG------- 26781

Query: 361   LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGE 420
             +S     +  +     DE      + T     G+    Y         D          +
Sbjct: 26782 VSGSDQTLTIKQASHRDEGILTCISKTKE---GIVKCQYDLTLSKELSDAPAFISQPRSQ 26838

Query: 421   TMSLGCRVVITPEIK-HFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 479
              ++ G  V+ T EI     PEI+W++N +P+S S  V    S    +L   + +  D G 
Sbjct: 26839 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26898

Query: 480   YTIRVR 485
             YTI+ +
Sbjct: 26899 YTIKAK 26904



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 46/190 (24%), Positives = 78/190 (41%), Gaps = 28/190 (14%)

Query: 1492 WSHNGSAI--RYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQ 1549
            W H+G  I   Y+ +V     G Q  L I   TP+D G++ +   +       +V L+ +
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDGTQS-LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1502

Query: 1550 AYDEAYAEF--QRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWL 1607
            A +        ++LK                   V I+EG  L +     G+P P++ WL
Sbjct: 1503 AVEHQVKPMFVEKLKN------------------VNIKEGSRLEMKVRATGNPNPDIVWL 1544

Query: 1608 KNEKALASDDHCNLKFEAGR-TAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFI- 1665
            KN   +    +  ++ E  +  A   I+   + DS  Y     NK G +T+   V+V + 
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604

Query: 1666 ---PEEEARM 1672
               PE E ++
Sbjct: 1605 FAEPEPERKL 1614



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 5/91 (5%)

Query: 1582 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD--DHCNLKFEAGRTAYFTINGVSTA 1639
            V + EG       ++ G P PEVSW ++ + +++       + F  GR A  TI  V+ A
Sbjct: 15   VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR-AKLTIPAVTKA 73

Query: 1640 DSGKYGLVVKNKYGSETSDFTVSVFIPEEEA 1670
            +SG+Y L   N  G  TS  T  + +  E A
Sbjct: 74   NSGRYSLKATNGSGQATS--TAELLVKAETA 102



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             DV+T++ G+ + +   V G P P+++W K  K L  +   +L  +  R     I     A
Sbjct: 11611 DVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE-LQIKEAVRA 11669

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             D GKY +  KN  G       V+V
Sbjct: 11670 DHGKYIISAKNSSGHAQGSAIVNV 11693



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  VV ++    L L   + G P PEV W K E  L   D   ++  +  T    I+ V+
Sbjct: 18808 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT--DRAQIEVTSSFTM-LVIDNVT 18864

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG+Y L ++N  GS+T+   V V
Sbjct: 18865 RFDSGRYNLTLENNSGSKTAFVNVRV 18890



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 56/255 (21%), Positives = 97/255 (38%), Gaps = 41/255 (16%)

Query: 238  KKSRKVVIREKAERLSLRKTLEETE---TYHAKLNEDHLL------HAPEFIIKPRSHTV 288
            ++  K V+  +  R+ + +T +      T+ A  N   +         P+ + + +  TV
Sbjct: 3145 QERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTV 3204

Query: 289  WEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTA 348
               +  +    I+G P+P+++WYK +  ++      K++ + +   +TL +     ED A
Sbjct: 3205 QSGKPARFCAVISGRPQPKISWYKEEQLLST-GFKCKFLHDGQ--EYTLLLIEAFPEDAA 3261

Query: 349  QYRASAMNVKG--ELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
             Y   A N  G    SA  SV V        E   +  A   PL   VT  G  +RF+  
Sbjct: 3262 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQ-- 3319

Query: 407  FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                               CRV  T        ++ WY     + PS++ +     +   
Sbjct: 3320 -------------------CRVSGT------DLKVSWYSKDKKIKPSRFFRMTQFEDTYQ 3354

Query: 467  LTFSHLNKEDEGLYT 481
            L  +    EDEG YT
Sbjct: 3355 LEIAEAYPEDEGTYT 3369



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 83/367 (22%), Positives = 145/367 (39%), Gaps = 60/367 (16%)

Query: 1181 SPRLEVESKGNKTKMTFKDLGMDDLG--IYSCDVTDTDGIASSYLIDEEELKRLLALSHE 1238
            SP  E++++G K  +T   + +D  G  +Y      T  I +   + E EL         
Sbjct: 5134 SPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILT---VKEIELDF------- 5183

Query: 1239 HKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNT 1298
                 VP+K    V + E+ Q RF      L+  A V +      I    K+ +  D   
Sbjct: 5184 ----AVPLKD---VTVPERRQARFECV---LTREANVIWSKGPDIIKSSDKFDIIADGKK 5233

Query: 1299 GIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGP 1358
             I+   +   Q +DEG YT +++ GK T  S  + V  +  K     E Q  +       
Sbjct: 5234 HIL--VINDSQFDDEGVYTAEVE-GKKT--SARLFVTGIRLKFMSPLEDQTVK------- 5281

Query: 1359 HFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEF 1418
                       GE    + C++++ K   H+VW+K++ ++             T+LI+  
Sbjct: 5282 ----------EGETATFV-CELSHEKM--HVVWFKNDAKLHTSR---------TVLISSE 5319

Query: 1419 SKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY 1478
             K      + +  DD  + K+++K +    +  ++E      +   D K     + I L 
Sbjct: 5320 GKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHD-KTAVEKDEITLK 5378

Query: 1479 SFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKT 1538
              V+   +D+ V W  +G  I  S +      G +  L+I +    DKG+YV +    KT
Sbjct: 5379 CEVS---KDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKT 5435

Query: 1539 GHQKTVD 1545
                TV+
Sbjct: 5436 KANVTVE 5442



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEA-GRTAYFTINGV 1636
             L  V+T++ G  + L   V G P PEV+W K++ A        +K +    ++ F++   
Sbjct: 11902 LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKA 11961

Query: 1637  STADSGKYGLVVKNKYGSETSDFTVSV 1663
               +D GKY +   N  GS  +  TV+V
Sbjct: 11962 KRSDGGKYVVTATNTAGSFVAYATVNV 11988



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 5/116 (4%)

Query: 1552  DEAYAEFQRLKQAAIAEKNR----ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWL 1607
             D  Y+E +    + I ++ +    A + G    ++T + G    +   + G P P+V+W 
Sbjct: 22318 DAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWK 22377

Query: 1608  KNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               E  L   D  ++     RT   T+      DSG+Y L ++N  G +T   TV V
Sbjct: 22378 LEEMRLKETDRVSITTTKDRTT-LTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22432



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G+   L  +V G P P + WL+ +K +     C +K      A   +      
Sbjct: 17328 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIRI 17386

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             D G+Y L   N  GS++    V V
Sbjct: 17387 DGGQYILRASNVAGSKSFPVNVKV 17410



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 1/94 (1%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P F+ K ++  + E   +++     G P P + W KN   I  H  P K  IE   G   
Sbjct: 1510 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYP-KIRIEGTKGEAA 1568

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            L+I+    +D+A Y A+A+N  G  +    V V+
Sbjct: 1569 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 66/302 (21%), Positives = 111/302 (36%), Gaps = 30/302 (9%)

Query: 224  KQATSALQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKP 283
            K+ +S+    E     S ++ + +  E L L   L E+  Y  K + +     P FI + 
Sbjct: 3599 KEFSSSFLSAEEEGLHSAELQLSKINETLEL---LSESPVYPTKFDSEKEGTGPIFIKEV 3655

Query: 284  RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
             +  +   +   L  ++ G P+P++ W+ N V +   A+  K++ +     H+L I    
Sbjct: 3656 SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSAD-YKFVFDG--DDHSLIILFTK 3712

Query: 344  FEDTAQYRASAMNVKGE--LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYAS 401
             ED  +Y   A N  G+   SAY  +  K    +  ET      S   L     P     
Sbjct: 3713 LEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP----- 3767

Query: 402  RFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS 461
                HF  +       +G        VV  P      P + W++    L  S +   + +
Sbjct: 3768 ----HFLKELKPIRCAQGLPAIFEYTVVGEP-----APTVTWFKENKQLCTSVYYTIIHN 3818

Query: 462  -GERATLTFSHLNKEDEGLYTIRVR--MGEYYEQYSAYVFVRDAD-----AEIEGAPAAP 513
                 T   +   +ED GLY  +    +GE        V + D D      + +  P AP
Sbjct: 3819 PNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAP 3878

Query: 514  LD 515
             D
Sbjct: 3879 ED 3880



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 43/211 (20%), Positives = 77/211 (36%), Gaps = 25/211 (11%)

Query: 1468 IQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPND-K 1526
            + + +E   +    T      +VNW      +   ++ K         L I++    D +
Sbjct: 4442 VDTVSEEGDIVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQ 4501

Query: 1527 GKYVMELFD--GKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTI 1584
            G+YV E  +  GKT                 A+   +K+AA   K +   L        +
Sbjct: 4502 GEYVCEALNDSGKTATS--------------AKLTVVKRAAPVIKRKIEPL-------EV 4540

Query: 1585 QEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKY 1644
              G     TC +   P     W K  + +   D C+++  +   +   I      D G+Y
Sbjct: 4541 ALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR-SSKYISSLEILRTQVVDCGEY 4599

Query: 1645 GLVVKNKYGSETSDFTVSVFIPEEEARMAAL 1675
                 N+YGS +   T++V +P  E ++  L
Sbjct: 4600 TCKASNEYGSVSCTATLTVTVPGGEKKVRKL 4630



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 72/365 (19%), Positives = 133/365 (36%), Gaps = 62/365 (16%)

Query: 124  LSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKE----AAAYIAQRNLLASEEGIT 179
            L G++ E  PSD +VP   G+  H   + D + E   E    A  +    NL   E  + 
Sbjct: 5925 LKGKKLE--PSDKVVPRSEGKV-HTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVE 5981

Query: 180  TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
             +K           +  T  + +TA  +   SR++   +      +   + + E  ++ +
Sbjct: 5982 FTKPL---------EDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGR 6032

Query: 240  SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
             RK+VI +      ++    + + +    N + +    EF+       V EKE  +  C 
Sbjct: 6033 VRKLVIHDCTPE-DIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECE 6091

Query: 300  IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
            ++     +V W+K+   I       KY I S+  +  L IN C  +D A+Y       + 
Sbjct: 6092 LSR-ENAKVKWFKDGAEIK---KGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTAR- 6146

Query: 360  ELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREG 419
              S   +V+        +E  F    + + +S                          E 
Sbjct: 6147 -TSGMLTVLE-------EEAVFTKNLANIEVS--------------------------ET 6172

Query: 420  ETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 479
            +T+ L C      E+     E+ WY+    +  +   + L  G +  L   + + ED G 
Sbjct: 6173 DTIKLVC------EVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6226

Query: 480  YTIRV 484
            Y  R+
Sbjct: 6227 YNCRL 6231



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 2/84 (2%)

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
            D++ I EG+ L++       P P VSW K+ K + + D   +K +   +A+  +     A
Sbjct: 8090 DIIVI-EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKND-HISAHLEVPKSVRA 8147

Query: 1640 DSGKYGLVVKNKYGSETSDFTVSV 1663
            D+G Y + ++NK GS T+   V V
Sbjct: 8148 DAGIYTITLENKLGSATASINVKV 8171



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 50/209 (23%), Positives = 82/209 (39%), Gaps = 25/209 (11%)

Query: 286   HTVWEKE-NVKLHCSIAGWPEP-RVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
             H V E+  +VK  C I  + +  +VTWY     +    N  KY I    G+  L +    
Sbjct: 25271 HAVGEEGGHVKYVCKIENYDQSTQVTWYFG---VRQLENSEKYEITYEDGVAILYVKDIT 25327

Query: 344   FEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASR- 402
               D   YR   +N  GE S+YA + VK  +  +D   ++   +   +           R 
Sbjct: 25328 KLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYD---YYCRRTMKKIKRRTDTMRLLERP 25384

Query: 403   --FEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSP----SKWV 456
               F +   +K        GE +  G  + + PE     P + WY++G  + P     K+ 
Sbjct: 25385 PEFTLPLYNK----TAYVGENVRFGVTITVHPE-----PHVTWYKSGQKIKPGDNDKKYT 25435

Query: 457   QTLWSGERATLTFSHLNKEDEGLYTIRVR 485
                  G    LT + +  +D+  YT+  R
Sbjct: 25436 FESDKG-LYQLTINSVTTDDDAEYTVVAR 25463



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G++  +  +++G P P + W+K ++ L++     +K     T+  ++      
Sbjct: 16246 DTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATS-LSVKDAVRV 16304

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             DSG Y L  KN  G  +    V V
Sbjct: 16305 DSGNYILKAKNVAGERSVTVNVKV 16328



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 5/96 (5%)

Query: 290   EKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQ 349
             E ++V     ++G P P + W K+  P+++   P   II      + L I     EDT  
Sbjct: 25503 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSL--GPNIEIIHEGLDYYALHIRDTLPEDTGY 25560

Query: 350   YRASAMNVKGELSAYASVVVKRY---KGEFDETRFH 382
             YR +A N  G  S  A + V+R    K EF     H
Sbjct: 25561 YRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEH 25596



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 1/81 (1%)

Query: 1583  TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
             +IQ G+ L +   V G P P +SW+K+ + L      N++  A  T      G +  D G
Sbjct: 18017 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEG-NKDDFG 18075

Query: 1643  KYGLVVKNKYGSETSDFTVSV 1663
             KY +   N  G+ T + +V V
Sbjct: 18076 KYTVTATNSAGTATENLSVIV 18096



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 40/166 (24%), Positives = 64/166 (38%), Gaps = 21/166 (12%)

Query: 1492 WSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAY 1551
            W  +GS IR S + +    G+   L I +   +D G+Y   L  G      T  L     
Sbjct: 4846 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKL----- 4900

Query: 1552 DEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEK 1611
                          + E+   R +  L + VT+ +G+ L L+C +  +   +V W K+ K
Sbjct: 4901 --------------VVEELPVRFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGK 4944

Query: 1612 ALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETS 1657
             +       +    G     TIN     D+G Y + V+N    E S
Sbjct: 4945 IVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECS 4990



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 61/309 (19%), Positives = 119/309 (38%), Gaps = 50/309 (16%)

Query: 1143 EVVVNVDDDGVISLN---FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKD 1199
            E V +++D  V   +   F C     K+   W ++    ++  + + E  G+  ++  KD
Sbjct: 6519 EFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6578

Query: 1200 LGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVK-SELAVEILEKG 1258
              +DD   Y+C V D    A  ++ +                  +PV+      +ILE  
Sbjct: 6579 CRLDDECEYACGVEDRKSRARLFVEE------------------IPVEIIRPPQDILEAP 6620

Query: 1259 QVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTF 1318
                   AE      +V ++ N   + +G K++M  +    I  + +  ++  D+G Y F
Sbjct: 6621 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGK--IHRLQICDIKPRDQGEYRF 6678

Query: 1319 QLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKC 1378
              +D +A     +     +     K A+   Q+ +   G      + ++           
Sbjct: 6679 IAKDKEARAKLELAAAPKI-----KTAD---QDLVVDVGKPLTMVVPYD----------- 6719

Query: 1379 KVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDK 1438
              A  K E    W+K+   +S  +  D      +  I E  K D G Y+++L++  GK +
Sbjct: 6720 --AYPKAEAE--WFKENEPLST-KTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAE 6774

Query: 1439 S--RLKLVD 1445
                LK++D
Sbjct: 6775 GFINLKVID 6783



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST- 1638
             D V ++ G+A  L  +V G PPP + W K+ K L       +K     T    +N  ST 
Sbjct: 15164 DTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN--LVNKDSTR 15221

Query: 1639  ADSGKYGLVVKNKYGSETSDFTVSV 1663
              DSG Y L   N  G     F V V
Sbjct: 15222 RDSGAYTLTATNPGGFAKHIFNVKV 15246



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 36/155 (23%), Positives = 63/155 (40%), Gaps = 16/155 (10%)

Query: 1510  TGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEK 1569
             +G+  W + N+    DK   +  L +         +   + + E      R ++ A++ K
Sbjct: 24167 SGDSAWKKSNKERIKDKQFTIGGLLEA-------TEYEFRVFAENETGLSRPRRTAMSIK 24219

Query: 1570  NRARVLGGLPDV------VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKF 1623
              +    G  P +      VT + G+A  L+C + G P P++ W +  K L       +  
Sbjct: 24220 TKL-TSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSS 24278

Query: 1624  EAGRTAYFTINGVSTADSGKYGLVVKNKYGS-ETS 1657
             + GRT   T+      D G Y  +  N+ G  ETS
Sbjct: 24279 D-GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 24312



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 112/546 (20%), Positives = 188/546 (34%), Gaps = 108/546 (19%)

Query: 1110 SYVFRVRAINQAGVGKPSDLAGPVVAETRP-----GTKEVVVNVDDDGVISLNFECDKMT 1164
            +Y F + A+  +  G+ S  +  V+   +      GTK V+             EC    
Sbjct: 2378 NYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVL-------------ECKVSV 2424

Query: 1165 PK-SEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            P  +   W  +    +   R++   KG K ++        D G Y   V     + ++  
Sbjct: 2425 PDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIV---GRVETNCN 2481

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
            +  E++K +  L       T  V  E  VE+   G    W               F +KE
Sbjct: 2482 LSVEKIKIIRGLRDLTCTETQNVVFE--VELSHSGIDVLWN--------------FKDKE 2525

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQK 1343
            I    KYK  I+ +  I ++ +  +  +DEG YTF   +   +   TV   G + K L  
Sbjct: 2526 IKPSSKYK--IEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVA-GGAISKPLTD 2582

Query: 1344 EAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEK 1403
            +   + QE                       + +C+VAN   ++   W +D + + +   
Sbjct: 2583 QTVAESQE----------------------AVFECEVAN--PDSKGEWLRDGKHLPLTNN 2618

Query: 1404 -HDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALS 1462
                 DG    LI   +K D  I E   K    K  ++LK+  EA          KI  +
Sbjct: 2619 IRSESDGHKRRLIIAATKLD-DIGEYTYKVATSKTSAKLKV--EAV---------KIKKT 2666

Query: 1463 ATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPT 1522
              +L +  T + +         V+   V W  NG  +  +++    V G    L+I    
Sbjct: 2667 LKNLTVTETQDAVFTVELTHPNVKG--VQWIKNGVVLESNEKYAISVKGTIYSLRIKNCA 2724

Query: 1523 PNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVV 1582
              D+  Y   L  G+ G    +                ++   I +K         P  V
Sbjct: 2725 IVDESVYGFRL--GRLGASARL---------------HVETVKIIKK---------PKDV 2758

Query: 1583 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
            T  E   +    +V  D  P V W      +   D   L  E  +     +  +S +D+G
Sbjct: 2759 TALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSER-KVHKLMLQNISPSDAG 2816

Query: 1643 KYGLVV 1648
            +Y  VV
Sbjct: 2817 EYTAVV 2822



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  VVTI+    L L   + G P PEV W ++     S D  +++  +  T    +  V+
Sbjct: 15561 LRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGE--SLDKASIESTSSYTLLI-VGNVN 15617

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSGKY L V+N  GS+++   V V
Sbjct: 15618 RFDSGKYILTVENSSGSKSAFVNVRV 15643



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  ++ I+ G +L L   + G P PEV W K +  +   D   +   +  T+   ++ V+
Sbjct: 16643 LRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIR--DAAIIDVTSSFTS-LVLDNVN 16699

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSGKY L ++N  G++++  TV V
Sbjct: 16700 RYDSGKYTLTLENSSGTKSAFVTVRV 16725



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 7/82 (8%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEK--ALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             ++ G ++ L     G P P   W K +   +L +D H    F        T+   +  D+
Sbjct: 22064 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST-----LTVENCNRNDA 22118

Query: 1642  GKYGLVVKNKYGSETSDFTVSV 1663
             GKY L V+N  GS++  FTV V
Sbjct: 22119 GKYTLTVENNSGSKSITFTVKV 22140



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 6/78 (7%)

Query: 1356  QGPHFVEYL-SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVD----EKHDFKDGI 1410
             Q PHF E L +  V  + N  L CKV    K   + WY+  +EI  D       +FK G 
Sbjct: 24621 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI-VKWYRQGKEIIADGLKYRIQEFKGGY 24679

Query: 1411  CTLLITEFSKKDAGIYEV 1428
               L+I   +  DA +Y+V
Sbjct: 24680 HQLIIASVTDDDATVYQV 24697



 Score = 39.7 bits (91), Expect = 0.025
 Identities = 34/135 (25%), Positives = 52/135 (38%), Gaps = 9/135 (6%)

Query: 245   IREKAERLSL-----RKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENV-KLHC 298
             I EK  ++S      +KT E T T   +      + +   I+     T    ++V K   
Sbjct: 26509 IHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAV 26568

Query: 299   SIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVK 358
                G P P   W K+   I      GKY +    G   LEI+  D  D+  Y  +  N  
Sbjct: 26569 KATGEPRPTAIWTKDGKAIT---QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSA 26625

Query: 359   GELSAYASVVVKRYK 373
             G +S+   + +K  K
Sbjct: 26626 GSVSSSCKLTIKAIK 26640



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 36/157 (22%), Positives = 63/157 (40%), Gaps = 10/157 (6%)

Query: 1511 GEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKN 1570
            G   W+   EP    K + V  L +GK    +   L+ Q   +     + ++     E  
Sbjct: 7325 GSDKWVACGEPVAETKME-VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAP 7383

Query: 1571 R----ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG 1626
                  ++L GL    T++ G  + L   V G P P+++W K +  L  D    ++    
Sbjct: 7384 EIFLDVKLLAGL----TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVP 7438

Query: 1627 RTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
            + +  TI     +D+G Y +   N  G  T+   V+V
Sbjct: 7439 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7475



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 11/191 (5%)

Query: 180   TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
             TS Q + S Q   S Q +ASKQ  +    ++S  S+ +     S  A S    +E+  + 
Sbjct: 26937 TSLQGSFSSQ---SVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEM 26993

Query: 240   SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
             S    +      +S    LE + +   K     +   P+    P   ++ E + + + C+
Sbjct: 26994 SSSSFMG-----ISNMTQLESSTSKMLKAGIRGI--PPKIEALPSDISIDEGKVLTVACA 27046

Query: 300   IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
               G P P VTW      I+     G++ IE+   + TL I     +D   Y  S  N  G
Sbjct: 27047 FTGEPTPEVTWSCGGRKIH-SQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 27105

Query: 360   ELSAYASVVVK 370
               SA  ++ ++
Sbjct: 27106 SDSATVNIHIR 27116



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 54/228 (23%), Positives = 97/228 (42%), Gaps = 27/228 (11%)

Query: 144  RQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQT-----TASKQSTA 198
            R KH  G T      ++EA   +    L+ S++ +    Q TA  Q      TA     +
Sbjct: 1113 RNKH--GETSASASLLEEADYEL----LMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYS 1166

Query: 199  SKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRKTL 258
              +    K+    R+  A    VV     + ++ +E       + +I+E   R+ ++ TL
Sbjct: 1167 EYEKEYEKEQALIRKKMAKDTVVVR----TYVEDQEFHISSFEERLIKEIEYRI-IKTTL 1221

Query: 259  EET------ETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYK 312
            EE       E     ++E   + +  F  + +++ + E   V  HC ++G+P P++ WYK
Sbjct: 1222 EELLEEDGEEKMAVDISESEAVESG-FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYK 1280

Query: 313  NQVPINVHANPGKYIIE-SRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
            +   I    +  +Y ++  + G  +L I     ED   Y A A N+KG
Sbjct: 1281 DGKRIK---HGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1325



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 63/315 (20%), Positives = 110/315 (34%), Gaps = 43/315 (13%)

Query: 171  LLASEEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSA- 229
            +L  +EGI T+  S        S +      +     +        SR   +S ++ S  
Sbjct: 1308 VLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRS 1367

Query: 230  -LQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTV 288
             ++        +R    R    R+S  + LEET+      ++   L+ P F++KP S   
Sbjct: 1368 PIRMSPARMSPARMSPARMSPARMSPGRRLEETDE-----SQLERLYKPVFVLKPVSFKC 1422

Query: 289  WEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTA 348
             E +  +    + G P P   W+ +   I V+    K +I+   G  +L I      D+ 
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQI-VNDYTHKVVIKED-GTQSLIIVPATPSDSG 1480

Query: 349  QYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFD 408
            ++   A N  G  S    + V+  + +                  V P          F 
Sbjct: 1481 EWTVVAQNRAGRSSISVILTVEAVEHQ------------------VKPM---------FV 1513

Query: 409  DKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGER--AT 466
            +K      +EG  + +  R    P      P+I W +N   + P K+ +    G +  A 
Sbjct: 1514 EKLKNVNIKEGSRLEMKVRATGNP-----NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAA 1568

Query: 467  LTFSHLNKEDEGLYT 481
            L       +D   YT
Sbjct: 1569 LKIDSTVSQDSAWYT 1583



 Score = 38.5 bits (88), Expect = 0.056
 Identities = 76/371 (20%), Positives = 137/371 (36%), Gaps = 83/371 (22%)

Query: 231  QQEETSEKKSRKVVIREKAERLSLRK--TLEETETYHAKLNEDH------LLHAPEFIIK 282
            + ++T E   +  VI +  +R+ + K  TL++  TY   +          ++     ++ 
Sbjct: 6281 RDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVP 6340

Query: 283  PRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGC 342
             +   V E++ V  +C +      +  W++N+  I    +  KYII  +  ++TL I   
Sbjct: 6341 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAI---FDSSKYIILQKDLVYTLRIRDA 6396

Query: 343  DFEDTAQYRASAMNVKGE-LSAYASVVVKR------------YKGEFDETRFHAGASTMP 389
              +D A Y  S  N +GE + + A+++V+                E     F    + + 
Sbjct: 6397 HLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLN 6456

Query: 390  LSFGVTPYGYASRFEIHFD-------DKF-------DVSFGREGETM-------SLGCRV 428
            ++   T  G     E+ FD       DK+       D  F  EGE +       S+   +
Sbjct: 6457 VTLKWTKNGE----EVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELL 6512

Query: 429  VI---TPEIKHFQPE--------------------IQWYRNGVPLSPSKWVQTLWSGERA 465
            +I   T  ++H + +                    ++WYRNG  +   K  +    G   
Sbjct: 6513 IIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIH 6572

Query: 466  TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLD------VKCL 519
             L       +DE  Y      G    +  A +FV +   EI   P   L+      V   
Sbjct: 6573 RLIIKDCRLDDECEYA----CGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLA 6628

Query: 520  EANKDYIIISW 530
            E NKD + + W
Sbjct: 6629 ELNKDKVEVQW 6639



 Score = 38.5 bits (88), Expect = 0.056
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 5/105 (4%)

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKAL--ASDDHCNLKFEAGRTAYFTINGVS 1637
            D + ++ G+ +++  +V G P P++ W KNE  +   +D     K E  R+   T   + 
Sbjct: 9101 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 9160

Query: 1638 TA---DSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLK 1679
             A   D G Y +   N+ GS   +  V V+      R  A+  +K
Sbjct: 9161 KAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIK 9205



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 27/122 (22%), Positives = 55/122 (45%), Gaps = 7/122 (5%)

Query: 1532 ELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALN 1591
            +L +G+ G Q+  +L   A++ A       ++    EK +  ++   P+ V + EG+   
Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQK----EKQKPDIVL-YPEPVRVLEGETAR 1813

Query: 1592 LTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNK 1651
              C V G P P+V+W  N + +       ++++     Y  I    + D+G+  +  +N 
Sbjct: 1814 FRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG--IHYLDIVDCKSYDTGEVKVTAENP 1871

Query: 1652 YG 1653
             G
Sbjct: 1872 EG 1873



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 36/174 (20%), Positives = 69/174 (39%), Gaps = 20/174 (11%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            F C+    K    W K+      S  + + S+G   K+  K++ +DD+      V +   
Sbjct: 5288 FVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSS 5347

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
             A   +++ +             + TV +  + AV   EK ++    +  K   +  V +
Sbjct: 5348 TAQLKVLEAD------------PYFTVKLHDKTAV---EKDEITLKCEVSK---DVPVKW 5389

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTV 1331
              + +EI   PKY +  D    I++  ++K   +D+G Y       K   + TV
Sbjct: 5390 FKDGEEIVPSPKYSIKADGLRRILK--IKKADLKDKGEYVCDCGTDKTKANVTV 5441



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 44/193 (22%), Positives = 74/193 (38%), Gaps = 20/193 (10%)

Query: 1489 KVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFD--GKT--GHQKTV 1544
            K+ W  NG  +  S   K    G+   L I      D+G+Y     +  GKT       +
Sbjct: 3679 KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3738

Query: 1545 DLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGG------LPDVVTIQ--EGKALNLTCNV 1596
            +  G+ + +   E      +A+A+      LGG      L ++  I+  +G        V
Sbjct: 3739 NSKGEGHKDTETE------SAVAKS--LEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTV 3790

Query: 1597 WGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSET 1656
             G+P P V+W K  K L +  +  +      +  F +N     DSG Y    +N  G  T
Sbjct: 3791 VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGEST 3850

Query: 1657 SDFTVSVFIPEEE 1669
                + V + + +
Sbjct: 3851 CAAELLVLLEDTD 3863



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 1/83 (1%)

Query: 1581  VVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTAD 1640
             +V  + G  + +   V G P P V+W K ++ L      N +  A  T    IN    +D
Sbjct: 14769 LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST-ILNINECVRSD 14827

Query: 1641  SGKYGLVVKNKYGSETSDFTVSV 1663
             SG Y L  +N  G      T+ V
Sbjct: 14828 SGPYPLTARNIVGEVGDVITIQV 14850



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 18/77 (23%), Positives = 36/77 (46%)

Query: 1587  GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
             G+ +++     G P P ++W K +  + ++ H  +      T+    NGV   D+G Y +
Sbjct: 24737 GEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVV 24796

Query: 1647  VVKNKYGSETSDFTVSV 1663
               KN++G +     + V
Sbjct: 24797 CAKNRFGIDQKTVELDV 24813



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 21/84 (25%), Positives = 33/84 (39%), Gaps = 3/84 (3%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G  + +   V G PPP V+W  NE+ L  +           ++   I     +
Sbjct: 10227 DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIE---TTAISSSMVIKNCQRS 10283

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
               G Y L+ KN+ G       V V
Sbjct: 10284 HQGVYSLLAKNEAGERKKTIIVDV 10307



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             +  ++T++ G  + L   V+G P P VSW K+   L   +   +  +        +  V+
Sbjct: 12996 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR-NLCTLELFSVN 13054

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG Y +  +N  GS+++   + V
Sbjct: 13055 RKDSGDYTITAENSSGSKSATIKLKV 13080



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 1583  TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
             ++Q G+ L +   + G P P ++W K+   L      N+      T   +I      D G
Sbjct: 16935 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT-LSIKETHKDDGG 16993

Query: 1643  KYGLVVKNKYGSETSDFTV 1661
             +YG+ V N  G +T+   +
Sbjct: 16994 QYGITVANVVGQKTASIEI 17012



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             + +  G+ + L   + G PPP  SW      L   +   ++    + A  TI   +  D+
Sbjct: 23443 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT-KVAKLTIRETTIRDT 23501

Query: 1642  GKYGLVVKNKYGSETSDFTVSVFI 1665
             G+Y L +KN  G  T+  T+ V I
Sbjct: 23502 GEYTLELKNVTG--TTSETIKVII 23523



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 8/93 (8%)

Query: 1578 LPDVVTIQEGKALNLTCNVWGDPPPEVSWLK-------NEKALASDDHCNLKFEAGRTAY 1630
            L + + ++EG  +N+   + G P P ++W K       N++ +  D H N K     T  
Sbjct: 9817 LKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KLVVDDTCT 9875

Query: 1631 FTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
              I     +D+G Y +   N  G+ + +  ++V
Sbjct: 9876 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9908



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 19/86 (22%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKN-----EKA----LASDDHCNLKFEAGRTAY 1630
             DV+ ++ G+ L +  ++ G P P +SW K+     E+A    +++D+H  L         
Sbjct: 19492 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLL--------- 19542

Query: 1631  FTINGVSTADSGKYGLVVKNKYGSET 1656
              T+      D+G+Y L +KN  G+ +
Sbjct: 19543 -TVKDCIRRDTGQYVLTLKNVAGTRS 19567



 Score = 36.6 bits (83), Expect = 0.21
 Identities = 99/530 (18%), Positives = 188/530 (35%), Gaps = 110/530 (20%)

Query: 1142 KEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLG 1201
            K++++   +    S  FEC      +  +W KD  +  +SP+    + G   K+   D+ 
Sbjct: 4817 KDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQ 4876

Query: 1202 MDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVP-VKSELAVEILEKGQV 1260
            + D G Y+C                     +L L ++ K  T   V  EL V  ++  + 
Sbjct: 4877 LSDAGEYTC---------------------VLRLGNKEKTSTAKLVVEELPVRFVKTLEE 4915

Query: 1261 RFW-MQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGII--------EMFMEKLQDE 1311
                ++ + L  + ++N    E+++      K+ +++   I+         + +    D 
Sbjct: 4916 EVTVVKGQPLYLSCELN---KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDT 4972

Query: 1312 DEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGE 1371
            D GTYT  +++      S+ V V +V +           +W+ K            V  +
Sbjct: 4973 DAGTYTVTVENANNLECSSCVKVVEVIR-----------DWLVK------PIRDQHVKPK 5015

Query: 1372 CNVLLKCKVANIKKETHIVWYKDEREISV---DEKHDFKDG-ICTLLITEFSKKDAGIYE 1427
               +  C +A  K   +I W+K   EI     D+    +DG    L I     +D   Y 
Sbjct: 5016 GTAIFACDIA--KDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYA 5073

Query: 1428 VILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY-----SFVT 1482
            V ++  R                       K+ L   ++++    E + +Y     SF  
Sbjct: 5074 VEIEGKR--------------------YPAKLTLGEREVELLKPIEDVTIYEKESASFDA 5113

Query: 1483 YYVE-DLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQ 1541
               E D+   W   G  +R S   +    G + +L +++   +  G+ + +  +  T   
Sbjct: 5114 EISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAIT--- 5170

Query: 1542 KTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPP 1601
             T  L+ +  +  +A    LK   + E+ +AR      + V  +E               
Sbjct: 5171 -TAILTVKEIELDFA--VPLKDVTVPERRQARF-----ECVLTREA-------------- 5208

Query: 1602 PEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNK 1651
              V W K    + S D  ++    G+     IN     D G Y   V+ K
Sbjct: 5209 -NVIWSKGPDIIKSSDKFDI-IADGKKHILVINDSQFDDEGVYTAEVEGK 5256



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 293   NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352
             ++++   I G P P VTW K+ + +   AN     IE+      L I  C+  DT ++  
Sbjct: 14488 SIRIFVPIKGRPAPEVTWTKDNINLKNRAN-----IENTESFTLLIIPECNRYDTGKFVM 14542

Query: 353   SAMNVKGELSAYASVVV 369
             +  N  G+ S + +V V
Sbjct: 14543 TIENPAGKKSGFVNVRV 14559



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKAL-ASDDHCNLKFEAGRTAYFTINGVST 1638
             DV+ +  G+   L  ++ G P P+V W K+ K L  +     +K    +T     + + T
Sbjct: 18410 DVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRT 18469

Query: 1639  ADSGKYGLVVKNKYGSETSDFTVSV 1663
              D G+Y L + N  G+++   TV V
Sbjct: 18470 -DGGQYILKLSNVGGTKSIPITVKV 18493



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 277 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
           P F+ + +S TV +   V+L   + G P P V +Y++   I    +   + I     +++
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD---FQISQEGDLYS 160

Query: 337 LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
           L I     ED+  Y  +A N  G  ++ A ++V+
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 38/153 (24%), Positives = 61/153 (39%), Gaps = 11/153 (7%)

Query: 221  VVSKQATSALQQEETSEKKSRKVVIREKA-ERLSLRKTLEETETYHAKLNEDHLLHAPEF 279
            V   +  +  + E T  ++ +    R KA  R    K    TE   A   ++    APE 
Sbjct: 7330 VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQE----APEI 7385

Query: 280  IIKPR---SHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
             +  +     TV     ++L  ++ G PEP++TW K  +   +     +  IE+     T
Sbjct: 7386 FLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM---ILKQDKRITIENVPKKST 7442

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
            + I      DT  Y   A+NV G  +A   V V
Sbjct: 7443 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7475



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             +VV  + G ++ L   + G P P + W K++K L ++    ++      A   I      
Sbjct: 20575 EVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRL 20633

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             +SG Y L ++N  GS ++   V +
Sbjct: 20634 NSGCYELKLRNAMGSASATIRVQI 20657



 Score = 35.4 bits (80), Expect = 0.47
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + I+ G++L +   V G P P V+W K+   +    +  +    G T+ F +   +  
Sbjct: 21661 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF-VRDATRD 21719

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
               G Y +  KN  GS  ++  V V
Sbjct: 21720 HRGVYTVEAKNASGSAKAEIKVKV 21743



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 2/64 (3%)

Query: 439 PEIQWYRNGVPLSPS--KWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAY 496
           PE+ W+R+G  +S S    VQ  +S  RA LT   + K + G Y+++   G      +A 
Sbjct: 35  PEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAE 94

Query: 497 VFVR 500
           + V+
Sbjct: 95  LLVK 98



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 1/75 (1%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             + ++ G  +     + G P P   W  +   + +D+H  ++ +   ++  TI      D+
Sbjct: 11215 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETD-NFSSVLTIKNCLRRDT 11273

Query: 1642  GKYGLVVKNKYGSET 1656
             G+Y + V N  GS+T
Sbjct: 11274 GEYQITVSNAAGSKT 11288



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             E++++   + G P PRVTW+K+ V I    N     I    G  +L +     +    Y 
Sbjct: 21669 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDVLGSTSLFVRDATRDHRGVYT 21725

Query: 352   ASAMNVKGELSAYASVVVKRYKGE 375
               A N  G   A   V V+   G+
Sbjct: 21726 VEAKNASGSAKAEIKVKVQDTPGK 21749



 Score = 34.7 bits (78), Expect = 0.80
 Identities = 83/448 (18%), Positives = 160/448 (35%), Gaps = 90/448 (20%)

Query: 1168 EFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG---------- 1217
            + +W+ +    E+S RL+    GN   +T  ++ + D G+YSC V +  G          
Sbjct: 3519 DVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSV 3578

Query: 1218 ----------------------IASSYLIDEEE-----------LKRLLALSHEHKFPTV 1244
                                   +SS+L  EEE           +   L L  E   P  
Sbjct: 3579 EGAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSES--PVY 3636

Query: 1245 PVKSELAVEILEKGQVRFWMQAEKLSGNA-------------KVNYIFNEKEIFEGPKYK 1291
            P K +   E      ++    A+   G+              K+ + FN   +     YK
Sbjct: 3637 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK 3696

Query: 1292 MHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGK--ATNHSTVVLVGDVFKKLQKEAEFQR 1349
               D +   + +   KL+DE E T       GK   + +  +   G+  K  + E+   +
Sbjct: 3697 FVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK 3756

Query: 1350 QEWIRKQG----PHFVEYLS-WEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKH 1404
               + K G    PHF++ L           + +  V      T + W+K+ +++     +
Sbjct: 3757 S--LEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPT-VTWFKENKQLCTSVYY 3813

Query: 1405 DF---KDGICTLLITEFSKKDAGIY-----------------EVILKD-DRGKDKSRLKL 1443
                  +G  T ++ +  ++D+G+Y                  V+L+D D      + K 
Sbjct: 3814 TIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKS 3873

Query: 1444 VDEAFKELMMEVCKKIALSATDLKIQ-STAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYS 1502
              EA ++      K  A+ A D + + +T     +        E+ ++++ H   A   S
Sbjct: 3874 TPEAPEDFPQTPLKGPAVEALDSEQEIATFVKDTILKAALITEENQQLSYEHIAKANELS 3933

Query: 1503 DRVKTGVTGEQIWLQINEPTPNDKGKYV 1530
             ++  G    Q  L+ ++ TP    +++
Sbjct: 3934 SQLPLGAQELQSILEQDKLTPESTREFL 3961



 Score = 34.7 bits (78), Expect = 0.80
 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L   + ++ G  + L   V G PPP+++W K    L      ++K       +     V+
Sbjct: 13394 LRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVN 13452

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               D+GKY L ++N  G +     V V
Sbjct: 13453 KYDAGKYILTLENSCGKKEYTIVVKV 13478



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 41/195 (21%), Positives = 77/195 (39%), Gaps = 19/195 (9%)

Query: 1389 IVWYKDEREISVDE----KHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLV 1444
            + W++D + IS       +  F DG   L I   +K ++G Y +   +  G+  S  +L+
Sbjct: 37   VSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELL 96

Query: 1445 ---DEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRY 1501
               + A    +  +        + +++Q    GI     V +Y          +G+ I+ 
Sbjct: 97   VKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPT-PVVKFY---------RDGAEIQS 146

Query: 1502 SDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR- 1560
            S   +    G+   L I E  P D G Y +   +       T +L  Q  +E  A+  + 
Sbjct: 147  SLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKT 206

Query: 1561 -LKQAAIAEKNRARV 1574
             +  A I+E  + R+
Sbjct: 207  IVSTAQISESRQTRI 221



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 7/94 (7%)

Query: 1577 GLPDVVTIQEGKALNLTCNVWGDPPPEVSWL---KNEKALASDDHC---NLKFE-AGRTA 1629
            G  D +  + G  + +   + G P P+ SW    K +KA+    H    + + E A  ++
Sbjct: 9510 GAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSS 9569

Query: 1630 YFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               I     + +GKY +  KNK G +T++  V V
Sbjct: 9570 VIIIPECKRSHTGKYSITAKNKAGQKTANCRVKV 9603



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 5/83 (6%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG-RTAYFTINGVSTAD 1640
             + ++ G +  +     G P PE++W + E          ++ E G      +I+     D
Sbjct: 17729 IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSIDNCDRND 17784

Query: 1641  SGKYGLVVKNKYGSETSDFTVSV 1663
             +GKY L ++N  GS+++  TV V
Sbjct: 17785 AGKYILKLENSSGSKSAFVTVKV 17807



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 10/87 (11%)

Query: 1582 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD----DHCNLKFEAGRTAYFTINGVS 1637
            + I  GK L +   V G P P   W K E  L  D    D+   K E        I    
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSE------LIIKDAL 8862

Query: 1638 TADSGKYGLVVKNKYGSETSDFTVSVF 1664
              D G+Y +   N  GS+ +   V VF
Sbjct: 8863 RKDHGRYVITATNSCGSKFAAARVEVF 8889



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 4/109 (3%)

Query: 1358 PHFVEYL-SWEVTGECNVLLKCKVANIKKETHIVWYKDEREI--SVDEKHDFKDGICTLL 1414
            P+FV+ L S  V     V L+ +V  I     + +Y+D  EI  S+D +   +  + +LL
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV-VKFYRDGAEIQSSLDFQISQEGDLYSLL 162

Query: 1415 ITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSA 1463
            I E   +D+G Y V   +  G+  S  +L+ +  +E+  +  K I  +A
Sbjct: 163  IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTA 211



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 5/67 (7%)

Query: 418  EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDE 477
            EG    L C+V + P++      ++WY N   + P   VQ +  G +  L  +  +  DE
Sbjct: 2412 EGTKAVLECKVSV-PDVT----SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDE 2466

Query: 478  GLYTIRV 484
            G Y + V
Sbjct: 2467 GPYKLIV 2473



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
             I+ G  L L+  + G P P+V+W K ++   +    ++     +     I   +  D G 
Sbjct: 10925 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK---LEIRNAAHEDGGI 10981

Query: 1644  YGLVVKNKYGSETSDFTVSV 1663
             Y L V+N  GS+T    V V
Sbjct: 10982 YSLTVENPAGSKTVSVKVLV 11001



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 13/87 (14%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG--RTAYFT---INGV 1636
             + ++ G ++ +   + G P PEV+W K        D+ NLK  A    T  FT   I   
Sbjct: 14481 LVVRAGLSIRIFVPIKGRPAPEVTWTK--------DNINLKNRANIENTESFTLLIIPEC 14532

Query: 1637  STADSGKYGLVVKNKYGSETSDFTVSV 1663
             +  D+GK+ + ++N  G ++    V V
Sbjct: 14533 NRYDTGKFVMTIENPAGKKSGFVNVRV 14559



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 38/176 (21%), Positives = 75/176 (42%), Gaps = 16/176 (9%)

Query: 1165 PKSEFSWSKD--YVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSY 1222
            P  E SW +D   +ST   P +++     + K+T   +   + G YS   T+  G A+S 
Sbjct: 33   PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATS- 91

Query: 1223 LIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEK 1282
                 EL     L      P   V+   ++ + +  QVR  ++   +     V +  +  
Sbjct: 92   ---TAEL-----LVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIP-TPVVKFYRDGA 142

Query: 1283 EIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD--GKATNHSTVVLVGD 1336
            EI     ++  I +   +  + + +   ED GTY+    +  G+AT+ + +++ G+
Sbjct: 143  EIQSSLDFQ--ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 43/204 (21%), Positives = 67/204 (32%), Gaps = 47/204 (23%)

Query: 278  EFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTL 337
            + I KP+  T  E   V    S++    P V W+   V I       K+ + S   +H L
Sbjct: 2750 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPS---DKHRLVSERKVHKL 2805

Query: 338  EINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPY 397
             +      D  +Y A    V G+L   A + V+                           
Sbjct: 2806 MLQNISPSDAGEYTA----VVGQLECKAKLFVET-------------------------- 2835

Query: 398  GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQ 457
                   +H           E +T S  C      E+ HF     W +NGV +  S+  +
Sbjct: 2836 -------LHITKTMKNIEVPETKTASFEC------EVSHFNVPSMWLKNGVEIEMSEKFK 2882

Query: 458  TLWSGERATLTFSHLNKEDEGLYT 481
             +  G+   L   + + ED   YT
Sbjct: 2883 IVVQGKLHQLIIMNTSTEDSAEYT 2906



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
             ++ G +  +T    G P P V W K +  L +  + +      RT+  TI   +  DSGK
Sbjct: 19893 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDT--TDSRTS-LTIENANRNDSGK 19949

Query: 1644  YGLVVKNKYGSETSDFTVSV 1663
             Y L ++N   + +    V V
Sbjct: 19950 YTLTIQNVLSAASLTLVVKV 19969



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 5/45 (11%)

Query: 418  EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG 462
            EGET    CRV   P     QP++ WY NG  +  SK  +  + G
Sbjct: 1808 EGETARFRCRVTGYP-----QPKVNWYLNGQLIRKSKRFRVRYDG 1847



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 17/89 (19%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALA-------SDDHCNLKFEAGRTAYFTIN 1634
             + +++G  + LT  + G P P   W K  + ++       S+ H  L           I 
Sbjct: 23841 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTEL----------VIK 23890

Query: 1635  GVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
                  DSG Y LV++NK G +     V V
Sbjct: 23891 EADRGDSGTYDLVLENKCGKKAVYIKVRV 23919



 Score = 31.6 bits (70), Expect = 6.8
 Identities = 44/203 (21%), Positives = 71/203 (34%), Gaps = 46/203 (22%)

Query: 278  EFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTL 337
            +F+      TV E E     C ++   +  V W+KN   ++        +I S    H L
Sbjct: 5270 KFMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRT---VLISSEGKTHKL 5325

Query: 338  EINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPY 397
            E+     +D +Q +A       ELS+ A + V                          PY
Sbjct: 5326 EMKEVTLDDISQIKAQVK----ELSSTAQLKVLE----------------------ADPY 5359

Query: 398  GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQ 457
                 F +   DK  V    E + ++L C V     +K       W+++G  + PS    
Sbjct: 5360 -----FTVKLHDKTAV----EKDEITLKCEVSKDVPVK-------WFKDGEEIVPSPKYS 5403

Query: 458  TLWSGERATLTFSHLNKEDEGLY 480
                G R  L     + +D+G Y
Sbjct: 5404 IKADGLRRILKIKKADLKDKGEY 5426



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 8/88 (9%)

Query: 1598 GDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTIN-GVS-TADSGKYGLVVKNKYGSE 1655
            GDP   V WL + K L + +   +  E G   Y +++ GV+ + DSG       NKYG  
Sbjct: 1684 GDPTMVVEWLHDGKPLEAANRLRMINEFG---YCSLDYGVAYSRDSGIITCRATNKYG-- 1738

Query: 1656 TSDFTVSVFIPEEEARMAALESLKGGKK 1683
             +D T +  I ++E  +     L  G+K
Sbjct: 1739 -TDHTSATLIVKDEKSLVEESQLPEGRK 1765



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 6/60 (10%)

Query: 419  GETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEG 478
            GET +  C      E+ +    ++WY  G  L PS  V     G+  TLT   +  ED G
Sbjct: 5905 GETATFDC------ELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAG 5958



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 1598 GDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETS 1657
            G P P  +W   +K L + D   +K      A   I+    +D G Y L ++N+  + + 
Sbjct: 7115 GYPRPTATWCFGDKVLETGDRVKMK-TLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7173

Query: 1658 DFTVSVFIPEEEARMAALESLKGGKKAK 1685
            +  V+V      AR +A + LK G   K
Sbjct: 7174 EIDVNVI-----ARPSAPKELKFGDITK 7196



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 7/91 (7%)

Query: 1592  LTCNVWGDPPPEVSWLKNEKALASDDHCNLKFE----AGRTAYFTINGVSTADSGKYGLV 1647
             L C V G P P V W +  K + +D    LK+      G      I  V+  D+  Y + 
Sbjct: 24642 LVCKVTGHPKPIVKWYRQGKEIIAD---GLKYRIQEFKGGYHQLIIASVTDDDATVYQVR 24698

Query: 1648  VKNKYGSETSDFTVSVFIPEEEARMAALESL 1678
               N+ GS +   ++ V +P +      LE +
Sbjct: 24699 ATNQGGSVSGTASLEVEVPAKIHLPKTLEGM 24729


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score =  257 bits (656), Expect = 8e-68
 Identities = 233/902 (25%), Positives = 381/902 (42%), Gaps = 102/902 (11%)

Query: 405   IHFDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGE 463
             +  D KF DV   + GE + +   +   P      P I W ++G+ +      + + +  
Sbjct: 19417 VMMDVKFRDVIVVKAGEVLKINADIAGRP-----LPVISWAKDGIEIEERARTEIISTDN 19471

Query: 464   RATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANK 523
                LT     + D G Y + ++        +    V D      G PA PL++  L A K
Sbjct: 19472 HTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKP----GPPAGPLEINGLTAEK 19527

Query: 524   DYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFR 583
                 +SW +P  DGG+ I  Y ++K E    +W+ C +  ++     VT L++G  YIFR
Sbjct: 19528 --CSLSWGRPQEDGGADIDYYIVEKRETSHLAWTIC-EGELQMTSCKVTKLLKGNEYIFR 19584

Query: 584   VRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTD 643
             V  VNK G+G P   S  + ALDP                             VP PPT 
Sbjct: 19585 VTGVNKYGVGEPLE-SVAIKALDPFT---------------------------VPSPPTS 19616

Query: 644   LSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDL 702
             L +T  T+  + L W +P    G E   Y +E+ E  +  W RVN + PV   R     L
Sbjct: 19617 LEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKK-PVYDLRVKSTGL 19675

Query: 703   AEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES 762
              EG  Y +RV   N+AG+  PSE + +    D + +P  P K     +  T++ ++W + 
Sbjct: 19676 REGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKP 19735

Query: 763   --KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLS 820
                    + GY +E   +    W+    + ++G+ +T  GL TG  Y+FRV++VN  G S
Sbjct: 19736 LFDGGAPITGYTVEYKKSDDTDWKTSIQS-LRGTEYTISGLTTGAEYVFRVKSVNKVGAS 19794

Query: 821   EYSQDSE---AIEVKAAIGGGVSPDVCPALSDEPGG----LTASRGR----VHEASPPT- 868
             + S  S+   A E +      +  ++   L  + G         RGR    V  + P T 
Sbjct: 19795 DPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTD 19854

Query: 869   FQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKK 928
              +  A + +  ++ SL  + +N  + +  K + T+Q  L+           +    + K 
Sbjct: 19855 LRTRAYVDTTDSRTSL--TIENANRNDSGKYTLTIQNVLS----------AASLTLVVKV 19902

Query: 929   TDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
              D   P PP +IT  +  ++S VL W  P+  GGA +  Y++  RE       K   +  
Sbjct: 19903 LD--TPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKRE----ASKKAWVSVT 19956

Query: 989   KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCS 1048
                +  +YK++NL+E  +Y F+V+  N  G+G P+   E  K  E     P PP  L  +
Sbjct: 19957 NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITE----KPSPPEKLGVT 20012

Query: 1049  EVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEG 1108
              + KDS+ L W  P H G + +  Y V+  E   K   W  +  A  K+ +  V GL+E 
Sbjct: 20013 SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK--NW--VKCAVAKSTHHVVSGLREN 20068

Query: 1109  VSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISL----NFECD--- 1161
               Y FRV A NQAG+  P +L  PV+ + +    E+ +       + +    N + D   
Sbjct: 20069 SEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPI 20128

Query: 1162  KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
                P  + + S+D V  + + R   E       +  K+    D G Y     ++ G   +
Sbjct: 20129 SGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKA 20188

Query: 1222  YLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNE 1281
             ++        ++ L      P  P    +  +I E+     W   +   G+   NYI  +
Sbjct: 20189 FI-------NIVVLDR----PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLK 20237

Query: 1282  KE 1283
             +E
Sbjct: 20238 RE 20239



 Score =  248 bits (632), Expect = 5e-65
 Identities = 214/828 (25%), Positives = 356/828 (42%), Gaps = 107/828 (12%)

Query: 429  VITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGE 488
            ++ P   + + E +W++   PLS +K + T  + E+ +       K D+G Y I ++   
Sbjct: 6647 MVVPYDAYPKAEAEWFKENEPLS-TKTIDT--TAEQTSFRILEAKKGDKGRYKIVLQ--N 6701

Query: 489  YYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDK 548
             + +   ++ ++  D      P    +++  E     + ++W++P  DGGS I+GY +++
Sbjct: 6702 KHGKAEGFINLKVIDV-----PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVER 6756

Query: 549  CEVGTDSWSQCNDTPVKFARFPVTGLIEGR-SYIFRVRAVNKMGIGFPSRVSEPVAALDP 607
             ++   +W    D   +   F VTGL +G   Y+FRV A N++G G P     PV     
Sbjct: 6757 RDIKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPV----- 6810

Query: 608  AEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHE 667
                                  E  S+  VPGPP ++++T+  R  V L+W+PP   G  
Sbjct: 6811 ----------------------EARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGA 6848

Query: 668  GIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEA 726
             I  Y +E  +  +  W    T +  +     + D+ EG+ Y FRVR  N  GVG+PS A
Sbjct: 6849 EITNYVIELRDKTSIRWDTAMT-VRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAA 6907

Query: 727  TEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-KD-AKELVGYYIEASVAGSGKWE 784
            T    V D ++ P  P  +  S  T +SV + WE   KD    ++GY IE    G   W 
Sbjct: 6908 TPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWI 6967

Query: 785  PCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVC 844
             CN   V    +   GL  G  Y++RV A N AG+S+ S+                    
Sbjct: 6968 RCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEIL------------------ 7009

Query: 845  PALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVS-----KV 899
                   G LTA    V      +  KD L    PN  ++   S    +   +     KV
Sbjct: 7010 -------GPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 7062

Query: 900  SET----------VQEELTPPPQKAAPQG------KSKSDPLKKKTD---RAPPSPPCDI 940
             ET             EL   P + + +G      +++   +  + D    A PS P ++
Sbjct: 7063 LETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKEL 7122

Query: 941  TCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISN 1000
               +  +DS+ L W+ PD  GG+ +TGY V  REV       W +  +  V++  + + +
Sbjct: 7123 KFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKT---WTKV-MDFVTDLEFTVPD 7178

Query: 1001 LKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWK 1060
            L +   Y F+V A N  G G P+ V E          VP PP ++K  +   +S+ L W 
Sbjct: 7179 LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMST-PATVPDPPENVKWRDRTANSIFLTWD 7237

Query: 1061 PPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQ 1120
            PP + G + + GY V+        D+W    E  +    ++V GL+EG  Y +RV+A+N+
Sbjct: 7238 PPKNDGGSRIKGYIVE--RCPRGSDKWVACGE-PVAETKMEVTGLEEGKWYAYRVKALNR 7294

Query: 1121 AGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISL----NFECDKMT---PKSEFSWSK 1173
             G  KPS     + A       E+ ++V     +++      E        P+ + +W+K
Sbjct: 7295 QGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTK 7354

Query: 1174 DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
              +  +   R+ +E+   K+ +T  D    D G Y  +  +  G A++
Sbjct: 7355 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATA 7402



 Score =  247 bits (631), Expect = 6e-65
 Identities = 233/877 (26%), Positives = 353/877 (40%), Gaps = 116/877 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P + W ++G  L P++ ++        TL    +N++D G YTI        +  +  + 
Sbjct: 12953 PTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLK 13012

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V D        P  P  VK  +   D  ++SW+ P  DGGS I  Y +DK E    +W+Q
Sbjct: 13013 VLDK-------PGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQ 13065

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              + T V      V  LIEG  Y FR+ A NK G+G P   +EP  A +P +         
Sbjct: 13066 VSAT-VPITSCSVEKLIEGHEYQFRICAENKYGVGDPV-FTEPAIAKNPYDP-------- 13115

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                                PG      ++  T+ ++ +SWKPP   G   I  Y +EK E
Sbjct: 13116 -------------------PGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRE 13156

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
                 NW +VN + P+         L EG  Y FRV   N AG G+PS+A++     D   
Sbjct: 13157 TQAVNWTKVNRK-PIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQY 13215

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCN-NNPVKGS 794
              P  P        T +SV +SW +        ++GY +E   A S  W  CN    ++ +
Sbjct: 13216 PPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13275

Query: 795   RFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAI---GGGVSPDVCPALSDEP 851
             RF   GL+    Y FRV AVN  G S+ S   +    K  +    G +  D+   L    
Sbjct: 13276 RFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRA 13335

Query: 852   GGLTASRGRVHEASPPTFQKDALLGSKPN-----KPSLPSSS---------QNLGQTEVS 897
             G        V    PP      +  SKPN     +  L   S         +N+ + +  
Sbjct: 13336 GVTMRLYVPVKGRPPP-----KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13390

Query: 898   KVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQP 957
             K   T++             GK +   + K  D   P PP ++T  E  +DS  + W+ P
Sbjct: 13391 KYILTLENSC----------GKKEYTIVVKVLD--TPGPPVNVTVKEISKDSAYVTWEPP 13438

Query: 958   DKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMA 1017
                GG+ I  Y V  R   D     W     +  S+ +++++NL+E   Y F+V A N  
Sbjct: 13439 IIDGGSPIINYVVQKR---DAERKSWSTVTTEC-SKTSFRVANLEEGKSYFFRVFAENEY 13494

Query: 1018  GLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDL 1077
             G+G P    +  K  +     PGP   LK   V K S  + WK P   G + + GY VD 
Sbjct: 13495 GIGDPGETRDAVKASQ----TPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 13550

Query: 1078  KEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET 1137
                  +E++W+ + ++   ++    + L EG  Y FRV A N+ G G PS++   VVA  
Sbjct: 13551 ---LTEENKWQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVAR- 13602

Query: 1138  RPGTKEVVVNVDDDGVISL--------NFECD---KMTPKSEFSWSKDYVSTEDSPRLEV 1186
                   V  ++D  G+  L        NF      K  P    SW K         R+ V
Sbjct: 13603 ---DDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13659

Query: 1187  ESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPV 1246
             ES    T +   D    D G Y+  + +  G     +         + +  +   PT P+
Sbjct: 13660 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTI--------SIKVVGKPGIPTGPI 13711

Query: 1247  KSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
             K +   E+  +     W   +   G+   NYI  +++
Sbjct: 13712 KFD---EVTAEAMTLKWAPPKDDGGSEITNYILEKRD 13745



 Score =  247 bits (630), Expect = 8e-65
 Identities = 216/807 (26%), Positives = 347/807 (42%), Gaps = 78/807 (9%)

Query: 438  QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
            +P+I W +  + L   K +      +++T+T     + D G Y I         + +A V
Sbjct: 7347 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAV--NVCGRATAVV 7404

Query: 498  FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
             V   D      P  P      +   +  +++W  P  DGGS I  Y +++    ++ W 
Sbjct: 7405 EVNVLDK-----PGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWH 7459

Query: 558  QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAA---LDPAEKARLK 614
            + + T VK   F  T LI  + YIFRV A N  G+G P + S P+ A    DP       
Sbjct: 7460 KLSST-VKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQAS-PITAKYQFDP------- 7510

Query: 615  SRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFV 673
                                   PGPPT L  ++ T+  V L+W  P   G   I  Y+V
Sbjct: 7511 -----------------------PGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWV 7547

Query: 674  EKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVG 733
            E+ +  T+ W R N ++PVK   + +  L   K Y FRV   N AG G+PS++TE  ++ 
Sbjct: 7548 ERLDPDTDKWVRCN-KMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIK 7606

Query: 734  DKLDIPKAPGKIIPSRNTDTSVVVSW--EESKDAKELVGYYIEASVAGSGKWEPCNNNPV 791
            D +D P  PGK        TSV ++W   E     ++  Y IE    G+ +W       V
Sbjct: 7607 DPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEG-V 7665

Query: 792  KGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEP 851
              ++    GL+ GQ Y FRVRAVN AG SE S+ S+ +  +  +     P     ++   
Sbjct: 7666 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN--- 7722

Query: 852  GGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETV---QEELT 908
              +T +   +    P       +      K  +         T V     TV    E   
Sbjct: 7723 --ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSL 7780

Query: 909  PPPQKAAPQGKSKS------DPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGG 962
               + AA     +S      D +  K     P PP  +  ++  +  + L W+ P   GG
Sbjct: 7781 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGG 7840

Query: 963  AEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
              I  Y +  +E +     +W +A   A  +  ++++++ E    QFQV A N AG+G P
Sbjct: 7841 RPIQRYVIEKKERLG---TRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHP 7897

Query: 1023 SAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKA 1082
            S  +E    E+ T + P PP  L  ++  +  + + WKPP  +G +P+ GY V++     
Sbjct: 7898 SEPTEILSIEDPT-SPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEM--CPV 7954

Query: 1083 KEDQWRGLNEAAIKNVYLKV-RGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA---ETR 1138
              ++W  +N   IK++  KV  G+     YV RVRA+N  GV +PS+++  VVA   + +
Sbjct: 7955 GTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCK 8014

Query: 1139 P----GTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTK 1194
            P     T +++V   +   I + F   +  P    SW KD    + S RL +++      
Sbjct: 8015 PTIDLETHDIIVIEGEKLSIPVPF---RAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8071

Query: 1195 MTFKDLGMDDLGIYSCDVTDTDGIASS 1221
            +        D GIY+  + +  G A++
Sbjct: 8072 LEVPKSVRADAGIYTITLENKLGSATA 8098



 Score =  244 bits (623), Expect = 5e-64
 Identities = 210/715 (29%), Positives = 320/715 (44%), Gaps = 77/715 (10%)

Query: 432   PEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHL---NKEDEGLYTIRVR--M 486
             P I   +P I W ++G PL  +  V      E AT T  H+   NK+D G YT+      
Sbjct: 17962 PVIGRPRPNISWVKDGEPLKQTTRVNV---EETATSTVLHIKEGNKDDFGKYTVTATNSA 18018

Query: 487   GEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFI 546
             G   E  S  V       E  G P  P  V+  E + D+++ISW+ PA  GG  I  Y +
Sbjct: 18019 GTATENLSVIVL------EKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYIV 18070

Query: 547   DKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALD 606
             +K +  T +W   + T  +     +T L  G  Y FR+ A N+ G               
Sbjct: 18071 EKRDTTTTTWHMVSATVAR-TTIKITKLKTGTEYQFRIFAENRYG--------------- 18114

Query: 607   PAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGH 666
                        SAP   + ++ +    E   PGPP    VT  ++  +++ W  P   G 
Sbjct: 18115 ----------KSAPLDSKAVIVQYPFKE---PGPPGTPFVTSISKDQMLVQWHEPVNDGG 18161

Query: 667   EGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSE 725
               I+ Y +E+ E  +  W ++N + P++  +F    L EG  Y F+V   N  G+G+PS+
Sbjct: 18162 TKIIGYHLEQKEKNSILWVKLN-KTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 18220

Query: 726   ATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKW 783
              +E  V  D  D P  P  I+ +RN   +V + W++       ++ GY +E      G+W
Sbjct: 18221 VSECFVARDPCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW 18277

Query: 784   EPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAI---GGGV 839
                +   V  + FT  GLV  Q Y FRV A NAAG  SE S  S AI  +  I      +
Sbjct: 18278 MKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASL 18337

Query: 840   SP---DVCPALSDEPGGLTAS-RGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTE 895
              P   DV    + E   L A  RG+        + KD   G +  + +     ++  Q  
Sbjct: 18338 DPKYKDVIVVHAGETFVLEADIRGK--PIPDVVWSKD---GKELEETAARMEIKSTIQKT 18392

Query: 896   VSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKT-DR-APPSPPCDITCLESFRDSMVLG 953
                V + ++ +      K +  G +KS P+  K  DR  PP  P  +T + +  +   L 
Sbjct: 18393 TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTA--EKCYLA 18450

Query: 954   WKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAA 1013
             W  P + GGA I+ Y +  RE        W + + + V    YK++ L     Y F+V A
Sbjct: 18451 WNPPLQDGGANISHYIIEKRET---SRLSWTQVSTE-VQALNYKVTKLLPGNEYIFRVMA 18506

Query: 1014  MNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGY 1073
             +N  G+G P        C  +    PGPP + + S + KDS+V+ W  PV  G T + GY
Sbjct: 18507 VNKYGIGEPLESGPVTACNPY--KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY 18564

Query: 1074  FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              ++ ++ +    +W   N+  + ++ L+V GL EG SY FRV A N AGVG+PS+
Sbjct: 18565 ILEKRDKEGV--RWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSE 18617



 Score =  240 bits (612), Expect = 1e-62
 Identities = 232/891 (26%), Positives = 374/891 (41%), Gaps = 101/891 (11%)

Query: 417   REGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             R G  + L   V   PE     P+I W +    L   + V   ++G+RAT      ++ D
Sbjct: 22688 RAGSDLVLDAAVGGKPE-----PKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSD 22742

Query: 477   EGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVD 536
              G YT+ V+     +  S  V V D+       P   L V  +   K    ++W  P  D
Sbjct: 22743 SGKYTLTVKNASGTKAVSVMVKVLDSPG-----PCGKLTVSRVTQEK--CTLAWSLPQED 22795

Query: 537   GGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPS 596
             GG+ I  Y +++ E    +W          + + VT LI+   YIFRVRAVNK G G P 
Sbjct: 22796 GGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYGPGVPV 22854

Query: 597   RVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVL 656
               SEP+ A +                              +P PP         + ++++
Sbjct: 22855 E-SEPIVARNSFT---------------------------IPSPPGIPEEVGTGKEHIII 22886

Query: 657   SW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCS 715
              W KP    G+E   Y V+K E  +  W RVN +  V   R  +  L EG  Y FRV   
Sbjct: 22887 QWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAV 22946

Query: 716   NSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYI 773
             N+AG  EPSEA+      +    P  P        T  S+ ++W +       ++VGY +
Sbjct: 22947 NAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVL 23006

Query: 774   EASVAGSGKWEPCNNN-PVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVK 832
             E     + +W   + N  ++ + FT   L  GQ Y FRV AVN  G+SEYS+    IE  
Sbjct: 23007 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 23066

Query: 833   AAI---GGGVSPDVCPALSDEPGGLTASRGRVHEASPP--TFQKDAL-LGSKPNKPSLPS 886
               I      ++ D+   ++   G        V    PP  T+ K  + L S+    ++  
Sbjct: 23067 ERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASR----AIID 23122

Query: 887   SSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESF 946
             ++++     V KV+     + T   +  +  GK  +  L K  D   P P   +   E  
Sbjct: 23123 TTESYSLLIVDKVNRYDAGKYTIEAENQS--GKKSATVLVKVYDTPGPCP--SVKVKEVS 23178

Query: 947   RDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMV 1006
             RDS+ + W+ P   GGA +  Y V  RE        ++    K  S+  Y+IS L E  +
Sbjct: 23179 RDSVTITWEIPTIDGGAPVNNYIVEKRE---AAMRAFKTVTTKC-SKTLYRISGLVEGTM 23234

Query: 1007  YQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSG 1066
             Y F+V   N+ G+G P   S+     E    VP  P  L+  +V K ++ L W+ P++ G
Sbjct: 23235 YYFRVLPENIYGIGEPCETSDAVLVSE----VPLVPAKLEVVDVTKSTVTLAWEKPLYDG 23290

Query: 1067  RTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLK--VRGLKEGVSYVFRVRAINQAGVG 1124
              + +TGY   L+  KA  ++W  +    +K   L+  V  L EG  Y+FR+RA N+ GV 
Sbjct: 23291 GSRLTGYV--LEACKAGTERW--MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVS 23346

Query: 1125  KPSDLAGPVVAE-----------TRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSK 1173
             +P +    V  +           T P   +  ++V     + L        P +  SW  
Sbjct: 23347 EPRETVTAVTVQDLRVLPTIDLSTMP---QKTIHVPAGRPVELVIPIAGRPPPAA-SWFF 23402

Query: 1174  DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLL 1233
                   +S R+ VE+     K+T ++  + D G Y+ ++ +  G  S       E  +++
Sbjct: 23403 AGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTS-------ETIKVI 23455

Query: 1234  ALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVN-YIFNEKE 1283
              L      PT P+K    ++ ++   +    +  +L G A ++ Y+  +++
Sbjct: 23456 ILDKPGP-PTGPIK----IDEIDATSITISWEPPELDGGAPLSGYVVEQRD 23501



 Score =  239 bits (609), Expect = 2e-62
 Identities = 243/973 (24%), Positives = 389/973 (39%), Gaps = 133/973 (13%)

Query: 339   INGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYG 398
             + G    DT +YR SA+N+ G+            K E      H                
Sbjct: 10406 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLH---------------- 10449

Query: 399   YASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQT 458
                   + F DK  +   R GE  +L  R    P+     P++ W+++   +        
Sbjct: 10450 ------LDFRDKLTI---RVGEAFALTGRYSGKPK-----PKVSWFKDEADVLEDDRTHI 10495

Query: 459   LWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKC 518
               +     L      + D G Y + V       +    V V D      G P  P+    
Sbjct: 10496 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRP----GPPVGPVSFD- 10550

Query: 519   LEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGR 578
              E  KDY++ISWK P  DGGS I  Y I+K EVG D W        K     V+ L+EG+
Sbjct: 10551 -EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAK-TTCKVSKLLEGK 10608

Query: 579   SYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVP 638
              YIFR+ A N  GI      S+P+ +     K R +                      VP
Sbjct: 10609 DYIFRIHAENLYGI------SDPLVSDSMKAKDRFR----------------------VP 10640

Query: 639   GPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFA 698
               P    VTE T+   +++W  P   G     Y +EK E  ++ W RV  +      +F 
Sbjct: 10641 DAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFR 10700

Query: 699   LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVS 758
             + DL EG  Y FRV   N  G+G+PS  ++     D +  P  P        T  SV ++
Sbjct: 10701 VPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLT 10760

Query: 759   WEESK--DAKELVGYYIEASVAGSGKWEPCNNNP--VKGSRFTCHGLVTGQSYIFRVRAV 814
             W+  +     +++GY +E    G  +W   N+ P     +++   GL  GQ+Y FRV AV
Sbjct: 10761 WQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAV 10820

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGR-VHEASPPTFQKDA 873
             NAAG S+ +   E + VK  +     P++          L A+  R  H     T +  A
Sbjct: 10821 NAAGESDPAHVPEPVLVKDRL---EPPELI---------LDANMAREQHIKVGDTLRLSA 10868

Query: 874   LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSD---------- 923
             ++   P  P +    ++      +++      ++TP   K   +  +  D          
Sbjct: 10869 IIKGVP-FPKVTWKKEDRDAPTKARI------DVTPVGSKLEIRNAAHEDGGIYSLTVEN 10921

Query: 924   PLKKKTDRA------PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVID 977
             P   KT          P PP D+   E  +DS  L WK+P   GG+ IT Y V  R+V  
Sbjct: 10922 PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDV-- 10979

Query: 978   GVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIA 1037
                 +W   +  +  ++++   +L E   Y F+VAA N  G G      +  K  +  + 
Sbjct: 10980 -ASAQWSPLSATS-KKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD-PLH 11036

Query: 1038  VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
              PGPP  L   +V K  + L W  P   G +P+TGY V+ +E   ++  W  +    + N
Sbjct: 11037 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQD--W--IKFKTVTN 11092

Query: 1098  VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR--PGTKEVVVNVDDDGVI- 1154
             +   V GL++G +Y FRV+A N  G+G P D   P+  + +  P + E+ V + +  V+ 
Sbjct: 11093 LECVVTGLQQGKTYRFRVKAENIVGLGLP-DTTIPIECQEKLVPPSVELDVKLIEGLVVK 11151

Query: 1155  ---SLNFEC-DKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSC 1210
                ++ F    +  P     W+ D    +      VE+    + +T K+    D G Y  
Sbjct: 11152 AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11211

Query: 1211  DVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLS 1270
              V++  G         + +   L +      PT P+     +++  +     W   +   
Sbjct: 11212 TVSNAAG--------SKTVAVHLTVLDVPGPPTGPIN---ILDVTPEHMTISWQPPKDDG 11260

Query: 1271  GNAKVNYIFNEKE 1283
             G+  +NYI  +++
Sbjct: 11261 GSPVINYIVEKQD 11273



 Score =  238 bits (606), Expect = 5e-62
 Identities = 256/1027 (24%), Positives = 414/1027 (40%), Gaps = 150/1027 (14%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             +N+K+   + G P+P VTW K      +     +   E+      L IN C   D+  Y 
Sbjct: 14709 DNIKVEIPVLGRPKPTVTWKKGD---QILKQTQRVNFETTATSTILNINECVRSDSGPYP 14765

Query: 352   ASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKF 411
              +A N+ GE+    ++ V    G            T P+ F      +            
Sbjct: 14766 LTARNIVGEVGDVITIQVHDIPGP----------PTGPIKFDEVSSDF------------ 14803

Query: 412   DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH 471
              V+F  +      G        I ++  E++          + WV+   +  R T   + 
Sbjct: 14804 -VTFSWDPPENDGGV------PISNYVVEMR------QTDSTTWVELATTVIRTTYKATR 14850

Query: 472   LNKEDEGLYTIRVRMGEYY---EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIII 528
             L    E  Y  RV+    Y      ++   V +   ++ G P  P   +     KD + I
Sbjct: 14851 LTTGLE--YQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTP---QVTAVTKDSMTI 14905

Query: 529   SWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVN 588
             SW +P  DGGSPILGY +++ E     W   +   V    F  +GL +G +Y FRV A N
Sbjct: 14906 SWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAEN 14965

Query: 589   KMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTE 648
               G   PS+ SEP+ ALDP +                            PG P  L++T 
Sbjct: 14966 MAGKSKPSKPSEPMLALDPIDP---------------------------PGKPVPLNITR 14998

Query: 649   ATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKS 707
              T   V L W KP    G +   Y VEK +     W + N    +++  F +  L E  +
Sbjct: 14999 HT---VTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILEN-EFTVSGLTEDAA 15054

Query: 708   YCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAK 766
             Y FRV   N+AG +  PSE ++     D ++ PK              V V ++++   K
Sbjct: 15055 YEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKI------------KVDVKFKDTVILK 15102

Query: 767   ELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDS 826
                 + +EA V  SG+  P       G        +  +   F    VN        +DS
Sbjct: 15103 AGEAFRLEADV--SGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNK---DSTRRDS 15157

Query: 827   EAIEVKAAIGGGVSPDVC-------PALSDEPGGLT--ASRGRVHEASPPTFQKDALLG- 876
              A  + A   GG +  +        P   + P  +T   S   V    PP     A +  
Sbjct: 15158 GAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDH 15217

Query: 877   --------SKPNKPSLPSSSQ--NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLK 926
                     S+    ++ S  Q   L  T++ K +E +   +     K       +S+P+ 
Sbjct: 15218 YIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV--NKYGVGEPLESEPVL 15275

Query: 927   KKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREA 986
                   PP PP +       +DSMV+ W  PD  GG+EI  Y V  R   D    +W + 
Sbjct: 15276 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERR---DKAGQRWIKC 15332

Query: 987   NVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK-CEEWTIAVPGPPHSL 1045
             N K +++  YK+S L E   Y+F++ A N AG+ APS  S  +K C+  T+  PGPP + 
Sbjct: 15333 NKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD--TVFKPGPPGNP 15390

Query: 1046  KCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRG 1104
             +  +  + S+ + W  P++ G + +TGY V++  A  +ED+W+ +   A +K     + G
Sbjct: 15391 RVLDTSRSSISIAWNKPIYDGGSEITGYMVEI--ALPEEDEWQIVTPPAGLKATSYTITG 15448

Query: 1105  LKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECD--- 1161
             L E   Y  R+ A+N  G+G+P+ + G   AE R    E+ ++ D   V+++   C    
Sbjct: 15449 LTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRL 15508

Query: 1162  ----KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
                 K  P  E  W++D+  + D  +  +ES  + T +   ++   D G Y   V ++ G
Sbjct: 15509 FVPIKGRPAPEVKWARDHGESLD--KASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG 15566

Query: 1218  IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV-N 1276
               S+++             +     T     +L V+ + K  V        L G +K+ N
Sbjct: 15567 SKSAFV-------------NVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15613

Query: 1277  YIFNEKE 1283
             YI  ++E
Sbjct: 15614 YIVEKRE 15620



 Score =  236 bits (602), Expect = 1e-61
 Identities = 213/769 (27%), Positives = 319/769 (41%), Gaps = 97/769 (12%)

Query: 398   GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPE-----------IQWYRN 446
             G   +F +   +   VS  RE E +      ++ P+I    PE           I+ +  
Sbjct: 12494 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI--LMPEQITIKAGKKLRIEAHVY 12551

Query: 447   GVPLSPSKWVQTLWSGERATLTFSHL----------------NKEDEGLYTIRVRMGEYY 490
             G P    KW +    GE   +T SHL                 ++D G Y++        
Sbjct: 12552 GKPHPTCKWKK----GEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGT 12607

Query: 491   EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCE 550
             +     V V DA     G P  P D+  ++A  D   +SW  P  DGGS I  Y ++KC+
Sbjct: 12608 DTQKIKVVVMDAP----GPPQPPFDISDIDA--DACSLSWHIPLEDGGSNITNYIVEKCD 12661

Query: 551   VGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEK 610
             V    W     +  K +   V  LI G+ YIFRVRA N+ GI  P    + VA       
Sbjct: 12662 VSRGDWVTALASVTKTS-CRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG-- 12718

Query: 611   ARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM 670
                                       VP  P +  VT+  +  + ++W  P   G   I+
Sbjct: 12719 --------------------------VPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPII 12752

Query: 671   -YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEV 729
              Y +E+ E  +  W + N  L V+S  +    L EG  Y FR+   N AG   PS+ TE 
Sbjct: 12753 GYLIERKERNSLLWVKANDTL-VRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEY 12811

Query: 730   TVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNN 789
                   +D P  P  I  +++T  S++ +  +     +++GY++EA      KW  CN  
Sbjct: 12812 VTARMPVDPPGKPEVIDVTKST-VSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTA 12870

Query: 790   P--VKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSP--DVCP 845
             P  +    +T  GL     Y FR  A  A  +S  S+ S+ + + A     V P  D+  
Sbjct: 12871 PHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAE---NVPPRIDLSV 12927

Query: 846   ALSD----EPGGLTASRGRVHEASPPT--FQKDALLGSKPNKPSLPSSSQNLGQTEVSKV 899
             A+      + G        V     PT  ++KD  L  KP +    +  +NL   E+  V
Sbjct: 12928 AMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL-LKPAEGIKMAMQRNLCTLELFSV 12986

Query: 900   SETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDK 959
             +     + T   + ++    SKS  +K K     P PP  +   + + D  +L W+ P +
Sbjct: 12987 NRKDSGDYTITAENSSG---SKSATIKLKV-LDKPGPPASVKINKMYSDRAMLSWEPPLE 13042

Query: 960   IGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GG+EIT Y V+ RE        W + +   V   +  +  L E   YQF++ A N  G+
Sbjct: 13043 DGGSEITNYIVDKRETSRP---NWAQVSA-TVPITSCSVEKLIEGHEYQFRICAENKYGV 13098

Query: 1020  GAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
             G P           +    PG       S + KD + + WKPP   G +P+TGY ++ +E
Sbjct: 13099 GDPVFTEPAIAKNPYD--PPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRE 13156

Query: 1080  AKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              +A    W  +N   I    LK  GL+EG  Y FRV AIN+AG GKPSD
Sbjct: 13157 TQAVN--WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 13203



 Score =  235 bits (600), Expect = 2e-61
 Identities = 248/1071 (23%), Positives = 420/1071 (39%), Gaps = 153/1071 (14%)

Query: 294   VKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRAS 353
             V+L   IAG P P  +W+     +       +  +E+   +  L I      DT +Y   
Sbjct: 23384 VELVIPIAGRPPPAASWFFAGSKLR---ESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23440

Query: 354   AMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDV 413
               NV G  S    V++    G                     P G     EI   D   +
Sbjct: 23441 LKNVTGTTSETIKVIILDKPGP--------------------PTGPIKIDEI---DATSI 23477

Query: 414   SFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLN 473
             +   E   +  G      P   +   +   +R G       W+    S  R+T  F+ L 
Sbjct: 23478 TISWEPPELDGGA-----PLSGYVVEQRDAHRPG-------WLPVSESVTRSTFKFTRLT 23525

Query: 474   KEDEGLYTI----RVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIIS 529
             + +E ++ +    R  +G Y +       V +  + I   P  P  ++  + ++D + ++
Sbjct: 23526 EGNEYVFRVAATNRFGIGSYLQSE-----VIECRSSIR-IPGPPETLQIFDVSRDGMTLT 23579

Query: 530   WKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNK 589
             W  P  DGGS + GY +++ EV  D W + N  PV   R+  TGL EG  Y  RV A+N 
Sbjct: 23580 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 23639

Query: 590   MGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEA 649
              G G PSR S+P+ A+DP           AP                 PG P +  VT+ 
Sbjct: 23640 RGSGKPSRPSKPIVAMDPI----------AP-----------------PGKPQNPRVTDT 23672

Query: 650   TRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSY 708
             TR+ V L+W  P   G   +  Y +E  +     W + NT  P K   + L  L +G  Y
Sbjct: 23673 TRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTT-PTKIREYTLTHLPQGAEY 23731

Query: 709   CFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKEL 768
              FRV   N+ G GEP+E      V + L+ P            D  +   ++E    ++ 
Sbjct: 23732 RFRVLACNAGGPGEPAEVPGTVKVTEMLEYP------------DYELDERYQEGIFVRQ- 23778

Query: 769   VGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLV-TGQSYIFRVRAVNAAGLS------- 820
              G  I  ++   GK  P      +G   +   ++ T +++   V      G S       
Sbjct: 23779 -GGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVL 23837

Query: 821   EYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPN 880
             E     +A+ +K  + G  +    P   D+   +     RV    P       +LG    
Sbjct: 23838 ENKCGKKAVYIKVRVIGSPNSPEGPLEYDD---IQVRSVRVSWRPPADDGGADILGYILE 23894

Query: 881   KPSLPSSSQNLGQTEVSKVSETVQE---------ELTPPPQKAAPQGKSKSDPLKKKTDR 931
             +  +P ++     + V   S  V+           ++   Q    +     +P+  KT  
Sbjct: 23895 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 23954

Query: 932   APPSPPCDIT-CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKA 990
              PP PP +    L+  + S+ L W +P   GG+ +TGYY+  +E       KW   N   
Sbjct: 23955 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKET---STDKWVRHNKTQ 24011

Query: 991   VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEV 1050
             ++   Y ++ L  +  YQF++ A N  GL   S  SE   C++     P  P  L+   +
Sbjct: 24012 ITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD-PFDKPSQPGELEILSI 24070

Query: 1051  RKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVS 1110
              KDS+ LQW+ P   G   + GY+V+ ++  + +  W+  N+  IK+    + GL E   
Sbjct: 24071 SKDSVTLQWEKPECDGGKEILGYWVEYRQ--SGDSAWKKSNKERIKDKQFTIGGLLEATE 24128

Query: 1111  YVFRVRAINQAGVGKPSDLAGPV----VAETRPGTKEVVVNVDDDGVISLNFECDKM-TP 1165
             Y FRV A N+ G+ +P   A  +     +   PG ++ + +V      +    C  +  P
Sbjct: 24129 YEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRP 24188

Query: 1166  KSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLID 1225
               +  W +       S + ++ S G    +T      +D G+Y+C       IA++ + +
Sbjct: 24189 LPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC-------IATNEVGE 24241

Query: 1226  EEELKRLLALSHEHKFPTVPVK--------SELAVEILEKGQ---VRFWMQAEKLSGNAK 1274
              E   +LL  +     P  P+K        S L + ++  G+      W   +KL  N++
Sbjct: 24242 VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 24301

Query: 1275  VNYIFNEKEI-----------FEGPKYKMHIDRNTGIIEMFME-KLQDEDE 1313
                I N +                 KYK+ +    G ++  ++ ++QD+ +
Sbjct: 24302 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPD 24352



 Score =  234 bits (597), Expect = 5e-61
 Identities = 319/1304 (24%), Positives = 521/1304 (39%), Gaps = 194/1304 (14%)

Query: 273   LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY 332
             L+  P F +   + TV   E++K+     G P P VTW+K+ VP+       +   ES  
Sbjct: 15772 LVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK---QTTRVNAESTE 15828

Query: 333   GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKG------EFDETRFHAGAS 386
                 L I     ED   Y     N  GE     +V+V    G      + DE      A 
Sbjct: 15829 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVT----AD 15884

Query: 387   TMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRN 446
             ++ LS+G   Y   S    +  +K D S                                
Sbjct: 15885 SITLSWGPPKYDGGSSINNYIVEKRDTS-------------------------------- 15912

Query: 447   GVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAE- 505
                   + W     +  R T+    L    E  Y  R+     Y + S Y+      A+ 
Sbjct: 15913 -----TTTWQIVSATVARTTIKACRLKTGCE--YQFRIAAENRYGK-STYLNSEPTVAQY 15964

Query: 506   ---IEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDT 562
                + G P  P+      +++D + + W +P  DGGS ++GY +++ E  +  W + N T
Sbjct: 15965 PFKVPGPPGTPVVTL---SSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKT 16021

Query: 563   PVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWT 622
             P+   +F  TGL EG  Y FRV A N +GIG PS+VSE   A DP +             
Sbjct: 16022 PIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDP------------ 16069

Query: 623   GQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTE 681
                            PG P  + VT   R+ V L WK P   G   I  Y VEK E    
Sbjct: 16070 ---------------PGRPEAIIVT---RNSVTLQWKKPTYDGGSKITGYIVEKKELPEG 16111

Query: 682   NWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV-GEPSEATEVTVVGDKLDIPK 740
              W + +    + +  F +  L E   Y FRV   N+AGV  EPSE+T      D++D P+
Sbjct: 16112 RWMKASFTNIIDT-HFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16170

Query: 741   APGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNN--PVKGSRF-- 796
                  +  +  DT VV + E  K   ++ G  I       G  E  N     +K + F  
Sbjct: 16171 IS---MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFAT 16227

Query: 797   --TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGL 854
               +    V   S  + ++A N AG     + S  + VK     G  P   P +     G+
Sbjct: 16228 SLSVKDAVRVDSGNYILKAKNVAG-----ERSVTVNVKVLDRPG--PPEGPVVIS---GV 16277

Query: 855   TASRGRVHEASPPTFQKDA------LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQ-EEL 907
             TA +  +  A  P  Q         ++  +     + +      QT   KV++ ++  E 
Sbjct: 16278 TAEKCTL--AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEY 16335

Query: 908   TPPPQKAAPQGKSK---SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
             T         G  +   S+P+  K     P  P         +DSM++ W++P   GG+E
Sbjct: 16336 TFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSE 16395

Query: 965   ITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSA 1024
             I GY +  R+  +G+  +W   + + + E   +++ L EN  Y+F+V+A N AGL  PS 
Sbjct: 16396 ILGYVLEKRDK-EGI--RWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSP 16452

Query: 1025  VSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE 1084
              S   K  +  I  PGPP++ K  ++ + S+ L W  P++ G   + GY V+  +    E
Sbjct: 16453 PSAYQKACD-PIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGE 16511

Query: 1085  DQWRGLNE-AAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKE 1143
               W        I    ++V  L E   Y FR+ AIN+AGVG+ +D+ GP++ E +    +
Sbjct: 16512 --WTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPD 16569

Query: 1144  V--------VVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKM 1195
             +        ++N+   G + L F   K  P  E  W K      D+  ++V S  + T +
Sbjct: 16570 IDLDLELRKIINIRAGGSLRL-FVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSL 16626

Query: 1196  TFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEIL 1255
                ++   D G Y+  + ++ G  S+++       R+L        P+ PV   L V  +
Sbjct: 16627 VLDNVNRYDSGKYTLTLENSSGTKSAFV-----TVRVL------DTPSPPV--NLKVTEI 16673

Query: 1256  EKGQVRFWMQAEKLSGNAKV-NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEG 1314
              K  V    +   L G +K+ NYI  ++E     K    +  N       +++LQ   EG
Sbjct: 16674 TKDSVSITWEPPLLDGGSKIKNYIVEKREATR--KSYAAVVTNCHKNSWKIDQLQ---EG 16728

Query: 1315  -TYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECN 1373
              +Y F++    A N   + L       + K AE           P     ++ +     +
Sbjct: 16729 CSYYFRV---TAENEYGIGLPAQTADPI-KVAEV----------PQPPGKITVDDVTRNS 16774

Query: 1374  VLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTL--LITEFSKKDAGIYEVILK 1431
             V L          + I+ Y  E +    EK      + +L  +IT  ++ +  ++ V+  
Sbjct: 16775 VSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAV 16834

Query: 1432  DDRGKDKSRLKLVDEAFKELMMEVCKKIALSA------TDLKIQSTAEGIQLYSFVTYYV 1485
             +++G+   R   V    K+L++E   K A S+       DLKI+    G    +      
Sbjct: 16835 NEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPT------ 16888

Query: 1486  EDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY 1529
                 + W+ +G  ++ + R+    + +   L I E   +D G+Y
Sbjct: 16889 ----ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16928



 Score =  233 bits (595), Expect = 9e-61
 Identities = 261/1020 (25%), Positives = 403/1020 (39%), Gaps = 115/1020 (11%)

Query: 237   EKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKL 296
             E+K R  ++  K  +  +  T  + +     +  +  ++A   +   ++    E    + 
Sbjct: 17088 ERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARD 17147

Query: 297   HCSIAGWPEPRVTWYKNQVPIN----VHANPGK---YIIESRYGMHTLEINGCDFEDTAQ 349
              C   G PEP +   +N++ +     V+        YI+E R           D  D   
Sbjct: 17148 PCDPPGTPEP-IMVKRNEITLQWTKPVYDGGSMITGYIVEKR-----------DLPDGRW 17195

Query: 350   YRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFE---IH 406
              +AS  NV  E     S + +  + EF     +A  +    S    P       E   I 
Sbjct: 17196 MKASFTNVI-ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRIS 17254

Query: 407   FDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERA 465
              D KF D      GET  L   V   P      P I+W R    +  S   +   +  +A
Sbjct: 17255 MDPKFRDTIVVNAGETFRLEADVHGKP-----LPTIEWLRGDKEIEESARCEIKNTDFKA 17309

Query: 466   TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
              L      + D G Y +R       + +   V V D      G P  P+ V  + + K  
Sbjct: 17310 LLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQVTGVTSEK-- 17363

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
               ++W  P  DGGS I  Y ++K E    +W+      V  +   VT L+EG  Y+FR+ 
Sbjct: 17364 CSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNS-LKVTKLLEGNEYVFRIM 17422

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             AVNK G+G P   S PV   +P                            ++PGPP  L 
Sbjct: 17423 AVNKYGVGEPLE-SAPVLMKNPF---------------------------VLPGPPKSLE 17454

Query: 646   VTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAE 704
             VT   +  + + W +P    G E I Y VEK +     W + N    +   R  +  L E
Sbjct: 17455 VTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRR-ITDLRLRVTGLTE 17513

Query: 705   GKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-- 762
                Y FRV   N+AGVGEPS AT      D +  P  P        T  S+ ++W +   
Sbjct: 17514 DHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIY 17573

Query: 763   KDAKELVGYYIEASVAGSGKWEPCN-NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSE 821
                 E++GY +E   A   +W+       ++ +RF    L   Q Y  RV A+N  GL E
Sbjct: 17574 DGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGE 17633

Query: 822   YSQDSEAIEVKAAIGGGVSPD---VCPAL---SDEPGGLTASRG---RVH---EASP-PT 868
                         ++ G V P+     P L   S+   G+    G   R+H   +  P P 
Sbjct: 17634 ----------ATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPE 17683

Query: 869   FQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKK 928
                    G   +K  +    + +  T++S +    + +      K      SKS  +  K
Sbjct: 17684 ITWSREEGEFTDKVQI---EKGVNYTQLS-IDNCDRNDAGKYILKLENSSGSKSAFVTVK 17739

Query: 929   TDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
                  P PP ++   E  +DS  L W+ P   GGA++  Y ++ RE       +   ANV
Sbjct: 17740 V-LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE-----STRKAYANV 17793

Query: 989   KA-VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKC 1047
              +  S+ ++K+ NL E  +Y F+V A N  G+G P    +  K  E     P PP  +  
Sbjct: 17794 SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAE----PPSPPGKVTL 17849

Query: 1048  SEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKE 1107
             ++V + S  L W+ P H G + V GY V+++      ++W  + E+ + N    V GL  
Sbjct: 17850 TDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGT--EKWSIVAESKVCNAV--VTGLSS 17905

Query: 1108  GVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVVNVDDDGVISLNFECDKM- 1163
             G  Y FRV+A N+ G   P  L  PV+A+    +P  K             L  E   + 
Sbjct: 17906 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIG 17965

Query: 1164  TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
              P+   SW KD    + + R+ VE     T +  K+   DD G Y+   T++ G A+  L
Sbjct: 17966 RPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENL 18025



 Score =  233 bits (594), Expect = 1e-60
 Identities = 253/971 (26%), Positives = 389/971 (40%), Gaps = 143/971 (14%)

Query: 290   EKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQ 349
             E  N +L   I G P P V+W K + P+   A   +  +ES     TL +  C   D  +
Sbjct: 13624 ENSNFRLKIPIKGKPAPSVSWKKGEDPL---ATDTRVSVESSAVNTTLIVYDCQKSDAGK 13680

Query: 350   YRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFG-VTPYGYASRFEIHFD 408
             Y  +  NV G      S+ V              G  T P+ F  VT      ++    D
Sbjct: 13681 YTITLKNVAGTKEGTISIKVVG----------KPGIPTGPIKFDEVTAEAMTLKWAPPKD 13730

Query: 409   DKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLT 468
             D      G E           IT  I   +  +           +KWV    + ++ T  
Sbjct: 13731 DG-----GSE-----------ITNYILEKRDSVN----------NKWVTCASAVQKTTFR 13764

Query: 469   FSHLNKEDEGLYTIRVRMGEYY---EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
              + L++  E  YT RV     Y   E   +   V     ++  AP  P     ++   D 
Sbjct: 13765 VTRLHEGME--YTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPP---NIVDVRHDS 13819

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
             + ++W  P   GGSPI GY ++  E  +  W + N TP++   F VTGL EG  Y FRV 
Sbjct: 13820 VSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVM 13879

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             A+N  G+G PS  SEPV ALDP +                              PP    
Sbjct: 13880 AINLAGVGKPSLPSEPVVALDPID------------------------------PPGKPE 13909

Query: 646   VTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAE 704
             V   TR+ V L W +P    GH+   Y VEK +  +++W + N  + V    F + DL E
Sbjct: 13910 VINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKAN-HVNVPECAFTVTDLVE 13968

Query: 705   GKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESK 763
             G  Y FR+R  N+AG +  PSE+TE  +  D+ +   AP  ++     D   +    ++ 
Sbjct: 13969 GGKYEFRIRAKNTAGAISAPSESTETIICKDEYE---APTIVLDPTIKDGLTI----KAG 14021

Query: 764   DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823
             D   L    I         W     + ++ S  T     T  S +  ++        EY+
Sbjct: 14022 DTIVLNAISILGKPLPKSSWSKAGKD-IRPSDIT-QITSTPTSSMLTIKYATRKDAGEYT 14079

Query: 824   QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPS 883
                  I      G  V   V   + D PG      G V E S  + +K  L  + P +  
Sbjct: 14080 -----ITATNPFGTKVE-HVKVTVLDVPG----PPGPV-EISNVSAEKATLTWTPPLEDG 14128

Query: 884   -LPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQ-----------------GKSK---S 922
               P  S  L + E S++  TV  E     +  A +                 GK +   S
Sbjct: 14129 GSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQS 14188

Query: 923   DPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGK 982
             +P+K      PP PP         +++  + WK+P   GG+EITGY+V  RE       +
Sbjct: 14189 EPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSL---R 14245

Query: 983   WREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPP 1042
             W  A    VS+   K++ L+E   Y+F+V+A N AG+G PS  S+    ++     PGPP
Sbjct: 14246 WVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD-AAYPPGPP 14304

Query: 1043  HSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW-RGLNEAAIKNVYLK 1101
              +   ++  K S  L W  P + G   +TGY V+    K  ++ W +     A++     
Sbjct: 14305 SNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVE--HQKVGDEAWIKDTTGTALRITQFV 14362

Query: 1102  VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG---------TKEVVVNVDDDG 1152
             V  L+    Y FR+ AIN AGVG+P+ +    + E              + +VV     G
Sbjct: 14363 VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRA---G 14419

Query: 1153  VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
             +    F   K  P  E +W+KD ++ ++  R  +E+  + T +   +    D G +   +
Sbjct: 14420 LSIRIFVPIKGRPAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTGKFVMTI 14477

Query: 1213  TDTDGIASSYL 1223
              +  G  S ++
Sbjct: 14478 ENPAGKKSGFV 14488



 Score =  233 bits (593), Expect = 2e-60
 Identities = 236/910 (25%), Positives = 381/910 (41%), Gaps = 117/910 (12%)

Query: 404   EIHFDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG 462
             +I  D KF D    + GE   L   V   P      P ++W ++G  L  +  ++   + 
Sbjct: 15088 KIKVDVKFKDTVILKAGEAFRLEADVSGRPP-----PTMEWSKDGKELEGTAKLEIKIAD 15142

Query: 463   ERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEAN 522
                 L      + D G YT+       + ++   V V D      G P  PL V   E  
Sbjct: 15143 FSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRP----GPPEGPLAVT--EVT 15196

Query: 523   KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIF 582
              +  ++SW  P  DGG+ I  Y + K E    +W+    + V+  +  VT L++G  YIF
Sbjct: 15197 SEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIF 15255

Query: 583   RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
             RV AVNK G+G P   SEPV A++P                              P PP 
Sbjct: 15256 RVMAVNKYGVGEPLE-SEPVLAVNPYGP---------------------------PDPPK 15287

Query: 643   DLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFD 701
             +  VT  T+  +V+ W  P    G E I Y VE+ +   + W + N +  +   R+ +  
Sbjct: 15288 NPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT-LTDLRYKVSG 15346

Query: 702   LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEE 761
             L EG  Y FR+   N+AG+  PS  +      D +  P  PG       + +S+ ++W +
Sbjct: 15347 LTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNK 15406

Query: 762   S--KDAKELVGYYIEASVAGSGKWEPCNNNP-VKGSRFTCHGLVTGQSYIFRVRAVNAAG 818
                    E+ GY +E ++    +W+       +K + +T  GL   Q Y  R+ A+N+ G
Sbjct: 15407 PIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEG 15466

Query: 819   LSE--------YSQDS---EAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPP 867
             L E         ++D      IE+ A +   V+   C  L          +GR   A   
Sbjct: 15467 LGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRL----FVPIKGR--PAPEV 15520

Query: 868   TFQKDALLGSKPNKPSLPSSSQ-------NLGQTEVSKVSETVQEELTPPPQKAAPQGKS 920
              + +D   G   +K S+ S+S        N+ + +  K   TV+               S
Sbjct: 15521 KWARDH--GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENS-----------SGS 15567

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
             KS  +  +     P PP D+   E  + S+ L W  P   GG++I  Y V  RE      
Sbjct: 15568 KSAFVNVRV-LDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTR--- 15623

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
              K          + ++K+  L+E   Y F+V A N  G+G P+  +E  K  E     P 
Sbjct: 15624 -KAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASER----PL 15678

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYL 1100
             PP  +   +V ++S+ L W+ P H G + + GY V+++   +  D+W     A +K    
Sbjct: 15679 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGS--DKWATC--ATVKVTEA 15734

Query: 1101  KVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR--PGTKEVVVNV-----DDDGV 1153
              + GL +G  Y FRV A N+ G+  P  L+ PV+A+    P   +++ N       +D  
Sbjct: 15735 TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLK 15794

Query: 1154  ISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVT 1213
             + + F   + TP    +W KD V  + + R+  ES  N + +T KD   +D+G Y   +T
Sbjct: 15795 VDVPF-IGRPTPA--VTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLT 15851

Query: 1214  DTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
             ++ G A        E   ++ L      PT PVK +   E+        W   +   G++
Sbjct: 15852 NSAGEAI-------ETLNVIVLDKPGP-PTGPVKMD---EVTADSITLSWGPPKYDGGSS 15900

Query: 1274  KVNYIFNEKE 1283
               NYI  +++
Sbjct: 15901 INNYIVEKRD 15910



 Score =  232 bits (592), Expect = 2e-60
 Identities = 212/734 (28%), Positives = 309/734 (42%), Gaps = 93/734 (12%)

Query: 439  PEIQWYRNGVPLS-PSKWVQTLW-----SGERATLTFSHLNKEDEGLYTIRV--RMGEYY 490
            P+I+W +N   +  P+  +Q        S  +  L+     +ED+G YT+    R+G  +
Sbjct: 9056 PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVF 9115

Query: 491  EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCE 550
                     R+   E+   P+ P ++   +   +   ++W  P  +GGS I  Y IDK +
Sbjct: 9116 ---------RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRD 9166

Query: 551  VGTD--SWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPA 608
                   W +  +T V+  R+ +  LI    Y FRVRAVNK GI    + S+ V   DP 
Sbjct: 9167 ASRKKAEWEEVTNTAVE-KRYGIWKLIPNGQYEFRVRAVNKYGISDECK-SDKVVIQDPY 9224

Query: 609  EKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEG 668
                                        +PGPP    V   T+  +++SW PP   G   
Sbjct: 9225 R---------------------------LPGPPGKPKVLARTKGSMLVSWTPPLDNGGSP 9257

Query: 669  IM-YFVEKCEAGTENWQRVN----TELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEP 723
            I  Y++EK E G+  W RV+    T++ +K   F +  L EG  Y FR    N+AG+G P
Sbjct: 9258 ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPP 9317

Query: 724  SEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE-ESKD-AKELVGYYIEASVAGSG 781
            SE ++  V GD +  P  P        T +S+ + W+  +KD    + GY +E    G+ 
Sbjct: 9318 SEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTT 9377

Query: 782  KWEPCNNNPVKGSRFTCHGLVTG----QSYIFRVRAVNAAGLSEYSQDSEAI-------E 830
             W+   N P K    TC  +V      + Y FRV+AVN AG SE S  +  I       E
Sbjct: 9378 DWKRV-NEPDK-LITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEE 9435

Query: 831  VKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQN 890
             +  I  G    +      +       +GR    S   F   A    K     +P  +Q 
Sbjct: 9436 PEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQ- 9494

Query: 891  LGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAP---------PSPPCDIT 941
            L   E S V       +  P  K +  GK       K   +           P PP D+ 
Sbjct: 9495 LETAENSSV-------IIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK 9547

Query: 942  CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
              +  R S  L WK PD  GG  I GY +  R  IDG    W + N    S   + + +L
Sbjct: 9548 VSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR-TIDG--KAWTKVNPDCGS-TTFVVPDL 9603

Query: 1002 KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
                 Y F+V A N  G+G P    +     +  I  P PP  LK   + K+++ L WKP
Sbjct: 9604 LSEQQYFFRVRAENRFGIGPPVETIQRTTARD-PIYPPDPPIKLKIGLITKNTVHLSWKP 9662

Query: 1062 PVHSGRTPVTGYFVDL---KEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAI 1118
            P + G +PVT Y V+         K++ WR  N+  ++ +   V  L EG  Y FRV+A+
Sbjct: 9663 PKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAV 9722

Query: 1119 NQAGVGKPSDLAGP 1132
            N AGV KPS   GP
Sbjct: 9723 NAAGVSKPSATVGP 9736



 Score =  228 bits (582), Expect = 3e-59
 Identities = 213/797 (26%), Positives = 332/797 (41%), Gaps = 96/797 (12%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVR--MGEYYEQYSAY 496
             P+  W + G  + PS   Q   +   + LT  +  ++D G YTI      G   E     
Sbjct: 14037 PKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVT 14096

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             V       ++ G P  P+++  + A K    ++W  P  DGGSPI  Y ++K E     W
Sbjct: 14097 VL------DVPGPPG-PVEISNVSAEK--ATLTWTPPLEDGGSPIKSYILEKRETSRLLW 14147

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             +  ++  ++  R   T LI+G  YIFRV AVN  G G P + SEPV  +D       +  
Sbjct: 14148 TVVSED-IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVD-------RFG 14198

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
             P                    PGPP    V+  T++   +SWK P   G   I  Y VE+
Sbjct: 14199 P--------------------PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVER 14238

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  W R   + PV   R  +  L EG +Y FRV   N AG+G PSEA++  ++ D 
Sbjct: 14239 REKKSLRWVRA-IKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA 14297

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEESK--DAKELVGYYIEASVAGSGKW-EPCNNNPVK 792
                P  P     +  T  S  ++W +       E+ GY +E    G   W +      ++
Sbjct: 14298 AYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALR 14357

Query: 793   GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS--QDSEAIEVKAAIGGGVSPDVCPALSDE 850
              ++F    L T + Y FR+ A+N AG+ E +   D E +E + A    +  ++   L   
Sbjct: 14358 ITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVR 14417

Query: 851   PGG----LTASRGRVHEASPPTFQKDAL-LGSKPNKPSLPSSS----QNLGQTEVSKVSE 901
              G         +GR   A   T+ KD + L ++ N  +  S +        + +  K   
Sbjct: 14418 AGLSIRIFVPIKGR--PAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 14475

Query: 902   TVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIG 961
             T++           P GK       +  D   P P  ++   +  +DS+ L W  P   G
Sbjct: 14476 TIEN----------PAGKKSGFVNVRVLDT--PGPVLNLRPTDITKDSVTLHWDLPLIDG 14523

Query: 962   GAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGA 1021
             G+ IT Y V  RE        +  A  K   +  YK++ L E   Y F+V A N  G+G 
Sbjct: 14524 GSRITNYIVEKREA---TRKSYSTATTKC-HKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14579

Query: 1022  PSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAK 1081
             P+  +E  K  E     P PP SL   ++ K ++ L W  P H G + +TGY ++ +  +
Sbjct: 14580 PTETTEPVKASE----APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQ--R 14633

Query: 1082  AKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGT 1141
                DQW  +    +K +   VR L EG  Y F+V A+N AG   P + + PV+ + +   
Sbjct: 14634 KGSDQWTHI--TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPVIVKEQTML 14690

Query: 1142  KE----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGN 1191
              E          V+    D+  + +        PK   +W K     + + R+  E+   
Sbjct: 14691 PELDLRGIYQKLVIAKAGDNIKVEIPV---LGRPKPTVTWKKGDQILKQTQRVNFETTAT 14747

Query: 1192  KTKMTFKDLGMDDLGIY 1208
              T +   +    D G Y
Sbjct: 14748 STILNINECVRSDSGPY 14764



 Score =  227 bits (579), Expect = 6e-59
 Identities = 229/893 (25%), Positives = 362/893 (40%), Gaps = 102/893 (11%)

Query: 425   GCRVVITPEIKHFQ-PEIQWYR-------NGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             G  V I  +IK    P + W++       N  P+     V  L   +  TL      + D
Sbjct: 9759  GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9818

Query: 477   EGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPA 534
              GLYTI     +G   ++    V  R       G P  P+  + + A  D + +SW  P 
Sbjct: 9819  TGLYTITAVNNLGTASKEMRLNVLGRP------GPPVGPIKFESVSA--DQMTLSWFPPK 9870

Query: 535   VDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGF 594
              DGGS I  Y I+K E    +W   +  P K   + +  L+EG  Y+FR+ A NK GIG 
Sbjct: 9871  DDGGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9929

Query: 595   PSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYV 654
             P         LD           S P T + + +        VPG P   +V+  TR+ +
Sbjct: 9930  P---------LD-----------SEPETARNLFS--------VPGAPDKPTVSSVTRNSM 9961

Query: 655   VLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR----FALFDLAEGKSYC 709
              ++W+ P   G   +  Y++E  +  ++ W+RVN + P+K+      + +  L EG  Y 
Sbjct: 9962  TVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRD-PIKAMTLGVSYKVTGLIEGSDYQ 10020

Query: 710   FRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-KDA-KE 767
             FRV   N+AGVG  S  ++     D +  P  P   +    T +S  + W    KD   +
Sbjct: 10021 FRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW-TKSSADLEWSPPLKDGGSK 10079

Query: 768   LVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 827
             + GY +E    G  +WE   +  V+G++    GL  G  Y FRVRAVN AG+ E  + ++
Sbjct: 10080 VTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD 10139

Query: 828   AIEVKAAIGGGVSPD------VCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNK 881
              IE+K  +   VSPD      V   +    GG+      V    PPT   +    + P +
Sbjct: 10140 VIEMKDRL---VSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQE 10196

Query: 882   PSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDIT 941
              ++ +++  +  + V K  +   + +     K     + K+  +       P   P    
Sbjct: 10197 ATIETTA--ISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTP--FL 10252

Query: 942   CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
                   +S  L W  P+  GG+ IT Y +  RE        W         + A  +  L
Sbjct: 10253 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRE---SDRRAWTPVTYTVTRQNA-TVQGL 10308

Query: 1002  KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
              +   Y F++AA N  G+G     SE     E  I VP  P  L+  EV K+++ L W P
Sbjct: 10309 IQGKAYFFRIAAENSIGMGPFVETSEALVIRE-PITVPERPEDLEVKEVTKNTVTLTWNP 10367

Query: 1062  PVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA 1121
             P + G + +  Y ++       E   +  N+  +   Y  V+GLKEG +Y +RV A+N  
Sbjct: 10368 PKYDGGSEIINYVLE-SRLIGTEKFHKVTNDNLLSRKY-TVKGLKEGDTYEYRVSAVNIV 10425

Query: 1122  GVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMT------PKSEFSWSKDY 1175
             G GKPS    P+  +       + ++  D   I +  E   +T      PK + SW KD 
Sbjct: 10426 GQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVG-EAFALTGRYSGKPKPKVSWFKDE 10484

Query: 1176  VSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSY----LIDEEELKR 1231
                 +  R  +++      +        D G Y   V ++ G    +    ++D      
Sbjct: 10485 ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR----- 10539

Query: 1232  LLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEI 1284
                       P  PV      E+ +   V  W       G+   NYI  +KE+
Sbjct: 10540 ----------PGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEV 10582



 Score =  225 bits (574), Expect = 2e-58
 Identities = 218/877 (24%), Positives = 354/877 (40%), Gaps = 106/877 (12%)

Query: 367   VVVKRYKGEFDETRFHAGASTM-----PLSFGVTPYGYASRFEIHFDDKFDVSFGREGET 421
             V+ +   G F E     GA T      P    + P  Y     +H  + F V     G+ 
Sbjct: 16141 VIARNAAGVFSEPSESTGAITARDEVDPPRISMDPK-YKDTIVVHAGESFKVDADIYGKP 16199

Query: 422   MSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYT 481
             +                P IQW +    LS +  ++   +    +L+     + D G Y 
Sbjct: 16200 I----------------PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYI 16243

Query: 482   IRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPI 541
             ++ +        +  V V D      G P  P+ +  + A K    ++WK P  DGGS I
Sbjct: 16244 LKAKNVAGERSVTVNVKVLDRP----GPPEGPVVISGVTAEK--CTLAWKPPLQDGGSDI 16297

Query: 542   LGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEP 601
             + Y +++ E     W+   D  V+     VT L+EG  Y FR+ AVNK G+G P   SEP
Sbjct: 16298 INYIVERRETSRLVWTVV-DANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE-SEP 16355

Query: 602   VAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPP 661
             V A +P                            +VP  P    VT  T+  +++ W+ P
Sbjct: 16356 VVAKNPF---------------------------VVPDAPKAPEVTTVTKDSMIVVWERP 16388

Query: 662   GQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV 720
                G   I+ Y +EK +     W R +  L +   R  +  L E   Y FRV   N+AG+
Sbjct: 16389 ASDGGSEILGYVLEKRDKEGIRWTRCHKRL-IGELRLRVTGLIENHDYEFRVSAENAAGL 16447

Query: 721   GEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVA 778
              EPS  +      D +  P  P        T +SV +SW +       E+ GY +E    
Sbjct: 16448 SEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDV 16507

Query: 779   GSGKWEPCNN-NPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGG 837
               G+W  C     +  +      L+    Y FR+ A+N AG+ E++     I V+  +  
Sbjct: 16508 SVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEA 16567

Query: 838   ---GVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQ----- 889
                 +  ++   ++   GG       +     P  +   + G   +   +  +S      
Sbjct: 16568 PDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV 16627

Query: 890   --NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFR 947
               N+ + +  K + T++             G   +    +  D   PSPP ++   E  +
Sbjct: 16628 LDNVNRYDSGKYTLTLENS----------SGTKSAFVTVRVLDT--PSPPVNLKVTEITK 16675

Query: 948   DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY 1007
             DS+ + W+ P   GG++I  Y V  RE       K   A V    + ++KI  L+E   Y
Sbjct: 16676 DSVSITWEPPLLDGGSKIKNYIVEKREATR----KSYAAVVTNCHKNSWKIDQLQEGCSY 16731

Query: 1008  QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 1067
              F+V A N  G+G P+  ++  K  E    VP PP  +   +V ++S+ L W  P H G 
Sbjct: 16732 YFRVTAENEYGIGLPAQTADPIKVAE----VPQPPGKITVDDVTRNSVSLSWTKPEHDGG 16787

Query: 1068  TPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS 1127
             + +  Y V++ +AK  E +W     A +K++   +  L +G  Y+FRV A+N+ G   P 
Sbjct: 16788 SKIIQYIVEM-QAKHSE-KWSEC--ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPR 16843

Query: 1128  DLAGPVVA-------ETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTED 1180
              LA P+VA       + +P      V V  D  I +        PK   +W+KD +  + 
Sbjct: 16844 SLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG---RPKPTITWTKDGLPLKQ 16900

Query: 1181  SPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             + R+ V    + T ++ K+   DD G Y   V +  G
Sbjct: 16901 TTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG 16937



 Score =  224 bits (572), Expect = 4e-58
 Identities = 288/1312 (21%), Positives = 517/1312 (39%), Gaps = 206/1312 (15%)

Query: 276   APEFIIKP------RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIE 329
             A + +I+P       S++V   +++K+   I+G P+P +TW K+ +P+       +  + 
Sbjct: 16851 AKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK---QTTRINVT 16907

Query: 330   SRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRY----KG--EFDETRFHA 383
                 + TL I     +D  QY  +  NV G+ +A   +V        KG  +FD+     
Sbjct: 16908 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDV---- 16963

Query: 384   GASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQW 443
              A ++ LS+    Y    +   +   K D +                             
Sbjct: 16964 SAESITLSWNPPLYTGGCQITNYIVQKRDTT----------------------------- 16994

Query: 444   YRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV---FVR 500
                      + W     +  R TL  + L    E  Y  R+     Y Q  A      V 
Sbjct: 16995 --------TTVWDVVSATVARTTLKVTKLKTGTE--YQFRIFAENRYGQSFALESDPIVA 17044

Query: 501   DADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCN 560
                 +  G P  P        +KD ++I W +P  +GGSP++GY +++ E  +  W++ N
Sbjct: 17045 QYPYKEPGPPGTPF---ATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVN 17101

Query: 561   DTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAP 620
              T +   +F    L EG  Y FRV A N +G+G  S+ SE   A DP +           
Sbjct: 17102 KTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDP---------- 17151

Query: 621   WTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAG 679
                              PG P  + V    R+ + L W  P   G   I  Y VEK +  
Sbjct: 17152 -----------------PGTPEPIMVK---RNEITLQWTKPVYDGGSMITGYIVEKRDLP 17191

Query: 680   TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDI 738
                W + +    +++ +F +  L E + Y FRV   N+AG + +PS++T      D++++
Sbjct: 17192 DGRWMKASFTNVIET-QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVEL 17250

Query: 739   PKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEAS--VAGSGKWEPCNNNPVKGSRF 796
             P+     +  +  DT VV + E  +   ++ G  +     + G  + E      +K + F
Sbjct: 17251 PRIS---MDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17307

Query: 797   TCHGLVT------GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGG-----GVSPDVC- 844
                 +V       G  YI  +RA N AG   +  + + ++      G     GV+ + C 
Sbjct: 17308 KALLIVKDAIRIDGGQYI--LRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17365

Query: 845   ----PALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVS 900
                 P L D  GG   S   V +          ++ S+    SL  +    G   V ++ 
Sbjct: 17366 LTWSPPLQD--GGSDISHYVVEKRETSRLAW-TVVASEVVTNSLKVTKLLEGNEYVFRIM 17422

Query: 901   ETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKI 960
                +  +  P + A         P+  K     P PP  +      +DSM + W +PD  
Sbjct: 17423 AVNKYGVGEPLESA---------PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSD 17473

Query: 961   GGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLG 1020
             GG+EI GY V  R+   G+  +W + N + +++   +++ L E+  Y+F+V+A N AG+G
Sbjct: 17474 GGSEIIGYIVEKRD-RSGI--RWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVG 17530

Query: 1021  APSAVSECFK-CEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
              PS  +  +K C+   +  PGPP +    +  K+S+ L W  P++ G + + GY V++  
Sbjct: 17531 EPSPATVYYKACD--PVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEI-- 17586

Query: 1080  AKAKEDQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR 1138
              KA E++W+ +  +  ++    ++  L E   Y  RV A+N+ G+G+ + + G V  E +
Sbjct: 17587 CKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDK 17646

Query: 1139  PGTKE----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVES 1188
                 E          +VV       I + F   K  P  E +WS++    E + ++++E 
Sbjct: 17647 LEAPELDLDSELRKGIVVRAGGSARIHIPF---KGRPTPEITWSRE--EGEFTDKVQIEK 17701

Query: 1189  KGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKS 1248
               N T+++  +   +D G Y   + ++ G  S+++  +                T     
Sbjct: 17702 GVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVK-------------VLDTPGPPQ 17748

Query: 1249  ELAVEILEKGQVRFWMQAEKLSGNAKV-NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEK 1307
              LAV+ + K       +   + G AKV NY+ +++E     K   ++          +E 
Sbjct: 17749 NLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE--STRKAYANVSSKCSKTSFKVEN 17806

Query: 1308  LQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWE 1367
             L   +   Y F++           V   D  K  +               P     ++  
Sbjct: 17807 L--TEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP--------------PSPPGKVTLT 17850

Query: 1368  VTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGI 1425
                + +  L  +       + ++ Y  E +    EK     +  +C  ++T  S      
Sbjct: 17851 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 17910

Query: 1426  YEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIAL------SATDLKIQSTAEGIQLYS 1479
             + V   +++GK   R+  V    K+L ++   K+        +  DLKI+    G    +
Sbjct: 17911 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN 17970

Query: 1480  FVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
                       ++W  +G  ++ + RV    T     L I E   +D GKY +
Sbjct: 17971 ----------ISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 18012



 Score =  219 bits (558), Expect = 2e-56
 Identities = 202/716 (28%), Positives = 292/716 (40%), Gaps = 101/716 (14%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTP-VKFAR 568
             P  P + + L+ ++  I I+W +P  DGGS I GY ++      D W        +K   
Sbjct: 15384 PGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATS 15443

Query: 569   FPVTGLIEGRSYIFRVRAVNKMGIGFPS----------RVSEPVAALD------------ 606
             + +TGL E + Y  R+ A+N  G+G P+          R+  P   LD            
Sbjct: 15444 YTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRAC 15503

Query: 607   ------------PA-------------EKARLKSRPSAPW----------TGQIIVTEEE 631
                         PA             +KA ++S  S             +G+ I+T E 
Sbjct: 15504 CTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVEN 15563

Query: 632   PSEGI----------VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGT 680
              S              PGPP DL V E T++ V L+W PP   G   I  Y VEK E+  
Sbjct: 15564 SSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTR 15623

Query: 681   ENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
             + +  V T     S  + +  L EG SY FRV   N  G+G P+E  E     ++   P 
Sbjct: 15624 KAYSTVATNCHKTS--WKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASER---PL 15678

Query: 741   APGKIIPSRNTDTSVVVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTC 798
              PGKI     T  SV +SWE  E      ++GY +E    GS KW  C    VK +  T 
Sbjct: 15679 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCAT--VKVTEATI 15736

Query: 799   HGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASR 858
              GL+ G+ Y FRV A N  G+S+  Q S  +  K  +       + PA        T   
Sbjct: 15737 TGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV-------IPPAFKLLFNTFTVLA 15789

Query: 859   GRVHEASPPTFQK--DALLGSKPNKPSLPSSSQNLGQTE---VSKVSETVQEELTPPPQK 913
             G   +   P   +   A+   K N P   ++  N   TE   +  + +  +E++     K
Sbjct: 15790 GEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVK 15849

Query: 914   AAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYR 973
                      + L       P  P   +   E   DS+ L W  P   GG+ I  Y V  R
Sbjct: 15850 LTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKR 15909

Query: 974   EVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE 1033
                D     W+  +   V+    K   LK    YQF++AA N    G  + ++      +
Sbjct: 15910 ---DTSTTTWQIVSA-TVARTTIKACRLKTGCEYQFRIAAENR--YGKSTYLNSEPTVAQ 15963

Query: 1034  WTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
             +   VPGPP +   +   +DS+ +QW  P+  G + V GY ++ KE  +    W  LN+ 
Sbjct: 15964 YPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNS--ILWVKLNKT 16021

Query: 1094  AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVV 1146
              I     K  GL+EGV Y FRV A N  G+GKPS ++   VA      PG  E ++
Sbjct: 16022 PIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAII 16077



 Score =  219 bits (557), Expect = 2e-56
 Identities = 204/808 (25%), Positives = 322/808 (39%), Gaps = 89/808 (11%)

Query: 439   PEIQWYRN--GVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAY 496
             PE+ W ++     L+ S  V+     + +  + +   + D G Y +           +A 
Sbjct: 11859 PEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATN-------TAG 11911

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
              FV  A   +   P    ++K ++ + D   + W  P  DGG  I  Y ++KCE     W
Sbjct: 11912 SFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW 11971

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             S  + T V      VT LIEG  YIFRVRA NK+G G P+  S+PV A    +K      
Sbjct: 11972 STYSAT-VLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTE-SKPVIAKTKYDK------ 12023

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
                                  PG P    VT+ ++  + + W PP   G + I  YF+EK
Sbjct: 12024 ---------------------PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEK 12062

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  W  VN +  +   R  + +L     Y FRV+  N  G+GEPS  +   V  D 
Sbjct: 12063 KEKHSTRWVPVN-KSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDP 12121

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIE-----ASVAGSGKWEPCN- 787
             ++ P  P        T  S+ + W +        ++GY +E     A  +    W+ CN 
Sbjct: 12122 IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNA 12181

Query: 788   NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPAL 847
                +    FT   L   Q Y FRV A N  G+   ++  EAI+ K  +     P++    
Sbjct: 12182 AAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEIL---EPPEI---- 12234

Query: 848   SDEPGGLTASRGR--VHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSET--- 902
                   L AS  +  +  A  P      L      +P+   + + +G   V +  +    
Sbjct: 12235 -----DLDASMRKLVIVRAGCPI----RLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLV 12285

Query: 903   -VQEELTPPPQKAAPQGKSKSDPLKKKTDRA---------PPSPPCDITCLESFRDSMVL 952
                  L  P       GK     +    ++A          P P  D+   +  + S  +
Sbjct: 12286 DTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHV 12345

Query: 953   GWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVA 1012
              W  P+  GG+++T Y V  RE       K        V + ++ ++NL     Y F+V 
Sbjct: 12346 SWAPPENDGGSQVTHYIVEKRE----ADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVT 12401

Query: 1013  AMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTG 1072
             A+N  G G P+ V +     +  ++ P PP  L+ +E+ K+S  L W PP+  G   + G
Sbjct: 12402 AVNEYGPGVPTDVPKPVLASD-PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12460

Query: 1073  YFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGP 1132
             Y    +E +   D+W     + +K++ L V GLKEG  Y FRV A N  GV  P +  G 
Sbjct: 12461 YITSYREEEQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGV 12518

Query: 1133  VVAETRPGTKEVVV--NVDDDGVISLNFECDKM-TPKSEFSWSKDYVSTEDSPRLEVESK 1189
               A+ +    ++++   +       L  E      P     W K       S  L V   
Sbjct: 12519 YEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKA 12578

Query: 1190  GNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
              + + +  KD+   D G YS    ++ G
Sbjct: 12579 DSSSILIIKDVTRKDSGYYSLTAENSSG 12606



 Score =  216 bits (551), Expect = 1e-55
 Identities = 206/784 (26%), Positives = 323/784 (41%), Gaps = 104/784 (13%)

Query: 475   EDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPA 534
             ED G+Y++ V      +  S  V V D        P  P D++  E  KD   ++WK+P 
Sbjct: 10910 EDGGIYSLTVENPAGSKTVSVKVLVLDK-------PGPPRDLEVSEIRKDSCYLTWKEPL 10962

Query: 535   VDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGF 594
              DGGS I  Y +++ +V +  WS  + T  K + F    L EG  Y+FRV A N+ G G 
Sbjct: 10963 DDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAENQYGRGP 11021

Query: 595   PSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYV 654
                  +P+ ALDP                              PGPP DL   +  ++ V
Sbjct: 11022 FVETPKPIKALDPLHP---------------------------PGPPKDLHHVDVDKTEV 11054

Query: 655   VLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVR 713
              L W  P + G   I  Y VE  E GT++W +  T   V +    +  L +GK+Y FRV+
Sbjct: 11055 SLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKT---VTNLECVVTGLQQGKTYRFRVK 11111

Query: 714   CSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYI 773
               N  G+G P   T + +   +  +P       PS   D  ++                I
Sbjct: 11112 AENIVGLGLPD--TTIPIECQEKLVP-------PSVELDVKLIEGLVVKAGTTVRFPAII 11162

Query: 774   EASVAGSGKWEPCNNNPVKGSRFT--------------CHGLVTGQSYIFRVRAVNAAGL 819
                   + KW    +       +T              C    TG+   +++   NAAG 
Sbjct: 11163 RGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGE---YQITVSNAAGS 11219

Query: 820   SEYSQDSEAIEVKAAIGGGVSP-DVCP---ALSDEP----GGLTASRGRVHEASPPTFQK 871
                +     ++V     G ++  DV P    +S +P    GG       V +      +K
Sbjct: 11220 KTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDT---RK 11276

Query: 872   DA--LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKT 929
             D   ++ S  +K  L       G   V +V    +  + PP           S P   K 
Sbjct: 11277 DTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLD---------STPTVAKH 11327

Query: 930   DRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVK 989
               +PPSPP      +   ++  + W  P   GG+ ITGYY+  RE    V GKW   N  
Sbjct: 11328 KFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERRE----VTGKWVRVNKT 11383

Query: 990   AVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK-CEEWTIAVPGPPHSLKCS 1048
              +++  ++++ L E   Y+F+V A N+AGL  PS  S+  K C    I  PGPP + K  
Sbjct: 11384 PIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACR--PIKPPGPPINPKLK 11441

Query: 1049  EVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRGLKE 1107
             +  +++  L W  P+  G +P+ GY V+ +  K    QW  +N +  I+    +V GL E
Sbjct: 11442 DKSRETADLVWTKPLSDGGSPILGYVVECQ--KPGTAQWNRINKDELIRQCAFRVPGLIE 11499

Query: 1108  GVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN-------FEC 1160
             G  Y FR++A N  G G+P +LA  V+A+      EV ++V    VI++           
Sbjct: 11500 GNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILAR 11559

Query: 1161  DKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
              K  P+ + +W+K+        R+++     + ++  K+    D G Y     ++ G A 
Sbjct: 11560 VKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQ 11619

Query: 1221  SYLI 1224
                I
Sbjct: 11620 GSAI 11623



 Score =  216 bits (550), Expect = 1e-55
 Identities = 215/827 (25%), Positives = 330/827 (39%), Gaps = 99/827 (11%)

Query: 417   REGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             R G TM L   V   P      P+I W +  V L     +    +     L   ++NK D
Sbjct: 13334 RAGVTMRLYVPVKGRPP-----PKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYD 13388

Query: 477   EGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVD 536
              G Y + +      ++Y+  V V D        P  P++V   E +KD   ++W+ P +D
Sbjct: 13389 AGKYILTLENSCGKKEYTIVVKVLDT-------PGPPVNVTVKEISKDSAYVTWEPPIID 13441

Query: 537   GGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPS 596
             GGSPI+ Y + K +    SWS    T      F V  L EG+SY FRV A N+ GIG P 
Sbjct: 13442 GGSPIINYVVQKRDAERKSWSTVT-TECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPG 13500

Query: 597   RVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVL 656
                + V A                                 PGP  DL V   ++S   +
Sbjct: 13501 ETRDAVKASQ------------------------------TPGPVVDLKVRSVSKSSCSI 13530

Query: 657   SWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSN 716
              WK P   G   I+ +V         WQRV   L   S +++  DL EGK Y FRV   N
Sbjct: 13531 GWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSL---SLQYSAKDLTEGKEYTFRVSAEN 13587

Query: 717   SAGVGEPSEATEVT---VVGDKLDIPKAPGKIIPSRNTDT-----------SVVVSWEES 762
               G G PSE T V    VV   LD+   P     ++               +  VSW++ 
Sbjct: 13588 ENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG 13647

Query: 763   KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEY 822
             +D        +      S +    N   +    + C     G+   + +   N AG  E 
Sbjct: 13648 EDP-------LATDTRVSVESSAVNTTLIV---YDCQKSDAGK---YTITLKNVAGTKE- 13693

Query: 823   SQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKP 882
                + +I+V    G    P     ++ E   L  +  +    S  T        S  NK 
Sbjct: 13694 --GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKW 13751

Query: 883   SLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-KSDPLKKKTDRAPPSPPCDIT 941
                +S+       V+++ E ++       +     G+  KS+P+  +     P  P    
Sbjct: 13752 VTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPN 13811

Query: 942   CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
              ++   DS+ L W  P K GG+ ITGY++ ++E    +   W+ AN   +    +K++ L
Sbjct: 13812 IVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL---WKRANKTPIRMRDFKVTGL 13868

Query: 1002  KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
              E + Y+F+V A+N+AG+G PS  SE     +  I  PG P  +    + ++S+ L W  
Sbjct: 13869 TEGLEYEFRVMAINLAGVGKPSLPSEPVVALD-PIDPPGKPEVI---NITRNSVTLIWTE 13924

Query: 1062  PVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA 1121
             P + G   +TGY V+ ++  +K   W   N   +      V  L EG  Y FR+RA N A
Sbjct: 13925 PKYDGGHKLTGYIVEKRDLPSK--SWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 13982

Query: 1122  G-VGKPSDLAGPVVAETR---------PGTKE-VVVNVDDDGVISLNFECDKMTPKSEFS 1170
             G +  PS+    ++ +           P  K+ + +   D  V++      K  PKS  S
Sbjct: 13983 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKS--S 14040

Query: 1171  WSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             WSK       S   ++ S    + +T K     D G Y+   T+  G
Sbjct: 14041 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14087



 Score =  216 bits (550), Expect = 1e-55
 Identities = 203/835 (24%), Positives = 345/835 (41%), Gaps = 98/835 (11%)

Query: 411   FDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFS 470
             FD    + GE++ +   V   P      P + W+++GV +     ++        +L   
Sbjct: 21593 FDGLIIKSGESLRIKALVQGRPV-----PRVTWFKDGVEIEKRMNMEITDVLGSTSLFVR 21647

Query: 471   HLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISW 530
                ++  G+YT+  +      +    V V+D   ++ G       ++      + + + W
Sbjct: 21648 DATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGP------IRFTNITGEKMTLWW 21701

Query: 531   KQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKM 590
               P  DG +PI  Y I+K E    +W+   D   +   +    LI G  Y FRV AVNK 
Sbjct: 21702 DAPLNDGCAPITHYIIEKRETSRLAWALIEDK-CEAQSYTAIKLINGNEYQFRVSAVNKF 21760

Query: 591   GIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEAT 650
             G+G P   S+PV A                   QI  T        VP  P     +  T
Sbjct: 21761 GVGRPLD-SDPVVA-------------------QIQYT--------VPDAPGIPEPSNIT 21792

Query: 651   RSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYC 709
              + + L+W +P    G E   Y +E+ E  +  W +V ++ P+   RF +  L EG  Y 
Sbjct: 21793 GNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYE 21852

Query: 710   FRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKE 767
             F V   N+AGVG  S  + +    + ++ P  P  +  +  + T+V + W +       E
Sbjct: 21853 FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGME 21912

Query: 768   LVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 827
             ++GY IE   A  G W   N      +R+T   L  G+ Y FRV A+N AG  +  + + 
Sbjct: 21913 IIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTG 21972

Query: 828   AIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV-----HEASP-PT---FQKDALLGSK 878
              I+   A+    +P++    + +   +  +   +     ++  P PT    + D+ L  +
Sbjct: 21973 TIK---AVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLR 22029

Query: 879   PNKPSLPSSS----QNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPP 934
              +  +  S S    +N  + +  K + TV+               SKS     K     P
Sbjct: 22030 ADIHTTDSFSTLTVENCNRNDAGKYTLTVEN-----------NSGSKSITFTVKV-LDTP 22077

Query: 935   SPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEE 994
              PP  IT  +  R S  L W  P   GGA I  Y V  RE        W+  + K  + +
Sbjct: 22078 GPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKRE---ASRRSWQVISEKC-TRQ 22133

Query: 995   AYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDS 1054
              +K+++L E + Y F+V+A+N  G+G P  + E     E     P PP  L   +  K S
Sbjct: 22134 IFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATE----QPAPPRRLDVVDTSKSS 22189

Query: 1055  LVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFR 1114
              VL W  P H G + +TGY +++++  +  D W  +     K +   V  L E   Y FR
Sbjct: 22190 AVLAWLKPDHDGGSRITGYLLEMRQKGS--DFW--VEAGHTKQLTFTVERLVEKTEYEFR 22245

Query: 1115  VRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMT---------- 1164
             V+A N AG  +P +    V+ +      ++    D  G+ +    C   +          
Sbjct: 22246 VKAKNDAGYSEPREAFSSVIIK----EPQIEPTADLTGITNQLITCKAGSPFTIDVPISG 22301

Query: 1165  -PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGI 1218
              P  + +W  + +  +++ R+ + +  ++T +T KD    D G Y   + +T G+
Sbjct: 22302 RPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGV 22356



 Score =  209 bits (533), Expect = 1e-53
 Identities = 206/802 (25%), Positives = 328/802 (40%), Gaps = 99/802 (12%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVR--MGEYYEQYSAY 496
             P I+WY++   L  +  V    + + A++     ++ + G Y +++R  MG      SA 
Sbjct: 20530 PTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMG------SAS 20583

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
               +R    +  G P  P++ K + A K  I + W+ PA DGG+ I  Y ++K E     W
Sbjct: 20584 ATIRVQILDKPGPPGGPIEFKTVTAEK--ITLLWRPPADDGGAKITHYIVEKRETSRVVW 20641

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             S  ++  ++      T +I+G  YIFRVRAVNK GIG P      VA             
Sbjct: 20642 SMVSE-HLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVA------------- 20687

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
                             +  + PGPP    VT+ T++ + + W  P   G   I  YF+EK
Sbjct: 20688 ---------------KNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEK 20732

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              +  +  W +V  E  ++  R  +  L E   Y +RV   N+AG G  SE +E     D 
Sbjct: 20733 RDKKSLGWFKVLKE-TIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADP 20791

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCN-NNPVK 792
             +D P  P KI  + +T +S+ + W +        + GY +E       +W   +    V+
Sbjct: 20792 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20851

Query: 793   GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPG 852
              + +    L  G +Y FRV AVN AG  E  + +E ++ K  +    +P++   ++    
Sbjct: 20852 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDIL---EAPEIDLDVALRTS 20908

Query: 853   GLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQ 912
              +  +   V    P         G  P   +     +NLG      +  T    L   PQ
Sbjct: 20909 VIAKAGEDVQVLIP-------FKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQ 20961

Query: 913   KAAPQ------------GKSKSDPLKKKTDRAPPSPPCD-ITCLESFRDSMVLGWKQPDK 959
                              G+ KS  +  K    P +  C  +      R ++ L W  P  
Sbjct: 20962 VTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAA--CQKLQVKHVSRGTVTLLWDPPLI 21019

Query: 960   IGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GG+ I  Y +  R   D     W   + K  S  ++K+ +L E   + F+V A N  G+
Sbjct: 21020 DGGSPIINYVIEKR---DATKRTWSVVSHKC-SSTSFKLIDLSEKTPFFFRVLAENEIGI 21075

Query: 1020  GAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
             G P   +E  K  E    VP P   L   +  K S++L W  P   G + +T Y V   E
Sbjct: 21076 GEPCETTEPVKAAE----VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---E 21128

Query: 1080  AKAKEDQ-WRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR 1138
              K K +Q W   +    K   ++V  LKE     FRV A N+ G+  P  + GP+  +  
Sbjct: 21129 RKGKGEQTWS--HAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI-GPITVKEL 21185

Query: 1139  -----------PGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVE 1187
                        PG  +V V +  +  + L +   K  PK   SW KD +  ++S  +   
Sbjct: 21186 IITPEVDLSDIPGA-QVTVRIGHNVHLELPY---KGKPKPSISWLKDGLPLKESEFVRFS 21241

Query: 1188  SKGNKTKMTFKDLGMDDLGIYS 1209
                NK  ++ K+   +  G Y+
Sbjct: 21242 KTENKITLSIKNAKKEHGGKYT 21263



 Score =  206 bits (525), Expect = 1e-52
 Identities = 199/815 (24%), Positives = 338/815 (41%), Gaps = 110/815 (13%)

Query: 438   QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
             +PE++W +    L+    ++   +     L   ++ + D G Y + +      +  +A+V
Sbjct: 18764 EPEVKWEKAEGILTDRAQIEV--TSSFTMLVIDNVTRFDSGRYNLTLENNSGSK--TAFV 18819

Query: 498   FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
              VR  D+     P+AP+++   E  KD + +SW+ P +DGG+ I  Y ++K E    +++
Sbjct: 18820 NVRVLDS-----PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18874

Query: 558   QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRP 617
                +   K   F +  L EG SY FRV A N+ GIG P+  +EPV   +P          
Sbjct: 18875 TITNNCTK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP---------- 18923

Query: 618   SAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKC 676
                                 P PP  +++ + TR+   + W+ P   G   I  Y VE  
Sbjct: 18924 --------------------PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQ 18963

Query: 677   EAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
               G+E W   +T   VK+    +  L  G+ Y FRV   N  G  +P +   V V+   +
Sbjct: 18964 TKGSEKW---STCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG-VPVIARDI 19019

Query: 737   DIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRF 796
             +I   P   +P     T  V + E+ K     +    +     +  W        + +R 
Sbjct: 19020 EIK--PSVELPFH---TFNVKAREQLK-----IDVPFKGRPQATVNWRKDGQTLKETTRV 19069

Query: 797   TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTA 856
                   T  S   +  +    G  E    + A        G ++  +   + D PG    
Sbjct: 19070 NVSSSKTVTSLSIKEASKEDVGTYELCVSNSA--------GSITVPITIIVLDRPG--PP 19119

Query: 857   SRGRVHEAS---------PPTFQKDALLGSKPNKPSLPSS------SQNLGQTEVSKVSE 901
                R+ E S         PP +     + +   +    +S      SQ + +T +  V  
Sbjct: 19120 GPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRL 19179

Query: 902   TVQEELTPPPQKAAPQGKS---KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPD 958
             T   E           GKS   +S  +  +   +PP PP     + + + +M++ W+ P 
Sbjct: 19180 TTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPV 19239

Query: 959   KIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAG 1018
               GG+ + GY++ Y+E    +   W +AN   +++   K+S L E ++Y+++V A N+AG
Sbjct: 19240 NDGGSRVIGYHLEYKERSSIL---WSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAG 19296

Query: 1019  LGAPSAVSECFKCEEWTIAVPG-----PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGY 1073
             +G         KC +    VP      PP   + + + + S+ L+W  P + G   +TGY
Sbjct: 19297 IG---------KCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGY 19347

Query: 1074  FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA-GVGKPSDLAGP 1132
              V+ +E    + +W   N   I+  Y +V  L E   Y FRV A N A  V +PS+  GP
Sbjct: 19348 IVERRELP--DGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGP 19405

Query: 1133  VVAETRPGTKEVVVNVDDDGVISLNF-ECDKMT------PKSEFSWSKDYVSTEDSPRLE 1185
             ++ +       V+++V    VI +   E  K+       P    SW+KD +  E+  R E
Sbjct: 19406 IIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTE 19465

Query: 1186  VESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
             + S  N T +T KD    D G Y   + +  G  S
Sbjct: 19466 IISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRS 19500



 Score =  206 bits (523), Expect = 2e-52
 Identities = 199/804 (24%), Positives = 355/804 (44%), Gaps = 75/804 (9%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P  +W  +G  +   +          + LT  +  + D G Y I V      +  + ++ 
Sbjct: 11168 PTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 11227

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V D    + G P  P+++  L+   +++ ISW+ P  DGGSP++ Y ++K +   D+W  
Sbjct: 11228 VLD----VPGPPTGPINI--LDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 11281

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              +    K  +  +  L +G  Y+FRVRA NK+G+G P   +  V        A+ K  P 
Sbjct: 11282 VSSGSSK-TKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTV--------AKHKFSPP 11332

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
             +P                 PG P    VT+ T +   +SW  P   G   I  Y++E+ E
Sbjct: 11333 SP-----------------PGKPV---VTDITENAATVSWTLPKSDGGSPITGYYMERRE 11372

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
               T  W RVN + P+   +F +  L EG +Y FRV   N AG+ +PS +++       + 
Sbjct: 11373 V-TGKWVRVN-KTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK 11430

Query: 738   IPKAP-GKIIPSRNTDTSVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNP-VKG 793
              P  P    +  ++ +T+ +V W +  S     ++GY +E    G+ +W   N +  ++ 
Sbjct: 11431 PPGPPINPKLKDKSRETADLV-WTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11489

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAI-GGGVSPDVC--PALSDE 850
               F   GL+ G  Y FR++A N  G  E  + +E++  K  +    V  DV     ++  
Sbjct: 11490 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVR 11549

Query: 851   PGGLTASRGRVHEASPP--TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELT 908
              G       RV     P  T+ K+  +  +  +  L    Q+L + E+ ++ E V+ +  
Sbjct: 11550 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL---IQDLPRVEL-QIKEAVRADHG 11605

Query: 909   PPPQKAA-PQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                  A    G ++   +    DR  P P  ++      +++  + W+ P   GG+EIT 
Sbjct: 11606 KYIISAKNSSGHAQGSAIVNVLDR--PGPCQNLKVTNVTKENCTISWENPLDNGGSEITN 11663

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             + V YR+     P +   + V +   +    +NL  N  Y F+V A N  G+G P+  ++
Sbjct: 11664 FIVEYRK-----PNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETK 11717

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW 1087
                     I  PG P +L  ++  K  + L+W+ P + G +P   Y V+ +  K  +D W
Sbjct: 11718 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVE-RRLKGSDD-W 11775

Query: 1088  RGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVN 1147
               +++ +IK  +  V    E   Y FRV+  N+ G    SD         +   ++ V++
Sbjct: 11776 ERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGG---ESDWVKTEEVVVKEDLQKPVLD 11832

Query: 1148  VDDDGVI------SLNFECD-KMTPKSEFSWSKDYVSTE--DSPRLEVESKGNKTKMTFK 1198
             +   GV+      ++  E   +  P  E +W+KD  +T+   SPR++++++ + +K +  
Sbjct: 11833 LKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT 11892

Query: 1199  DLGMDDLGIYSCDVTDTDGIASSY 1222
                  D G Y    T+T G   +Y
Sbjct: 11893 KAKRSDGGKYVVTATNTAGSFVAY 11916



 Score =  204 bits (519), Expect = 6e-52
 Identities = 197/777 (25%), Positives = 323/777 (41%), Gaps = 98/777 (12%)

Query: 474  KEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQP 533
            + D GLY I+V       +    V V D        P  P++    +  K  ++  W+ P
Sbjct: 8401 RPDHGLYMIKVENDHGIAKAPCTVSVLDT-------PGPPINFVFEDIRKTSVLCKWEPP 8453

Query: 534  AVDGGSPILGYFIDKCE-VGTDS-WSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMG 591
              DGGS I+ Y ++K +    DS W     T ++  ++ VT LIEG+ Y+FRVRA N+ G
Sbjct: 8454 LDDGGSEIINYTLEKKDKTKPDSEWIVVTST-LRHCKYSVTKLIEGKEYLFRVRAENRFG 8512

Query: 592  IGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATR 651
             G P  VS+P+ A DP                              P  P    V + T 
Sbjct: 8513 PG-PPCVSKPLVAKDPFGP---------------------------PDAPDKPIVEDVTS 8544

Query: 652  SYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFR 711
            + +++ W  P   G   + Y++EK E  + +W RVN  L + + +  +  L EG +Y FR
Sbjct: 8545 NSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVDGLLEGLTYVFR 8603

Query: 712  VRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTS---VVVSWEES--KDAK 766
            V   N+AG G+ S  ++     D +  P  P   IP R TDTS   + + WE        
Sbjct: 8604 VCAENAAGPGKFSPPSDPKTAHDPISPPGPP---IP-RVTDTSSTTIELEWEPPAFNGGG 8659

Query: 767  ELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDS 826
            E+VGY+++  + G+ +W  C    +K  ++T   +  G  Y  RV AVNAAG     +  
Sbjct: 8660 EIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQ 8719

Query: 827  EAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPS 886
                 +      V  DV        GG+    G+       T +  A++  +P    + +
Sbjct: 8720 PVTVAEPQEPPAVELDV-----SVKGGIQIMAGK-------TLRIPAVVTGRPVPTKVWT 8767

Query: 887  SSQ-----------NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPS 935
              +           N+G      + + ++++       A     SK    + +     P 
Sbjct: 8768 KEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV-PG 8826

Query: 936  PPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEA 995
            P  D+  + + R   +L W  P+  GG+EITG+ +  +   D     WR+     +  E 
Sbjct: 8827 PVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERK---DAKMHTWRQ----PIETER 8879

Query: 996  YK--ISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
             K  I+ L E   Y+F+V A N  G G P  +      +   +  P  P  L  +E  K 
Sbjct: 8880 SKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVD--PLGPPTSPERLTYTERTKS 8937

Query: 1054 SLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVF 1113
            ++ L WK P  +G +P+ GY ++ K    K D +  +N+         V  L E   Y F
Sbjct: 8938 TITLDWKEPRSNGGSPIQGYIIE-KRRHDKPD-FERVNKRLCPTTSFLVENLDEHQMYEF 8995

Query: 1114 RVRAINQAGVGKPSDLAGPVVAETR-PGTKEVVVNVDDDGV-----ISLNFECDKM-TPK 1166
            RV+A+N+ G  +PS     V+ +   P T ++ ++V  D +       ++   D    P 
Sbjct: 8996 RVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM 9055

Query: 1167 SEFSWSKDYVSTE------DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             +  WSK+    E         + EV     KT+++      +D G Y+   ++  G
Sbjct: 9056 PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 9112



 Score =  202 bits (515), Expect = 2e-51
 Identities = 243/1051 (23%), Positives = 411/1051 (39%), Gaps = 156/1051 (14%)

Query: 274   LHAPEFIIKP-RSHTVWEK--ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIES 330
             L  PE  +K   SHTV+ +   N+K+   I+G P P+VT  ++ VP+         I   
Sbjct: 20099 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 20158

Query: 331   RYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
                  T+ +      D  +Y  +A N  G   A+ ++VV              G  T P+
Sbjct: 20159 NL---TINLKESVTADAGRYEITAANSSGTTKAFINIVVLD----------RPGPPTGPV 20205

Query: 391   SFG-VTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVP 449
                 +T      ++E     K+D            G +V     +K              
Sbjct: 20206 VISDITEESVTLKWE---PPKYDG-----------GSQVTNYILLKR------------E 20239

Query: 450   LSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIE 507
              S + W +   +  R  +    L   +E  + I+   R G      SA V V+       
Sbjct: 20240 TSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVK-LPYTTP 20298

Query: 508   GAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFA 567
             G P+ P         ++ I + W +P  +GGS ++GY ++  +  +  W + N   ++  
Sbjct: 20299 GPPSTPW---VTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTT 20355

Query: 568   RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIV 627
              F VT +  G  Y FRV A N  G+G PS  SEPV A+D  E                  
Sbjct: 20356 HFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACE------------------ 20397

Query: 628   TEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRV 686
                         PP ++ +T+ +++ V LSW+ P   G   I  Y VE+ +     W + 
Sbjct: 20398 ------------PPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKA 20445

Query: 687   NTELPVKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKI 745
             +    V   +F +  L +   Y FRV   N+ G +  PSE     VVG    I    G +
Sbjct: 20446 SFT-NVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSE-----VVGPITCIDSYGGPV 20499

Query: 746   IPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQ 805
             I      T VV         K   G  ++     SGK  P             + LV  +
Sbjct: 20500 IDLPLEYTEVV---------KYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE 20550

Query: 806   SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEAS 865
             +    + ++        +     ++++ A+G   S  +   + D+PG      G   E  
Sbjct: 20551 NTT-DLASILIKDADRLNSGCYELKLRNAMGSA-SATIRVQILDKPG----PPGGPIEFK 20604

Query: 866   PPTFQKDALLGSKPNKPSLPS------SSQNLGQTEVSKVSETVQEELTPPPQ------- 912
               T +K  LL   P               +   +   S VSE ++E +    +       
Sbjct: 20605 TVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEY 20664

Query: 913   --------KAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
                     K       +SD +  K     P PP      +  ++SM + W +P   GG++
Sbjct: 20665 IFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSD 20724

Query: 965   ITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSA 1024
             I+GY++  R   D     W +   + + +   K++ L EN  YQ++V A+N AG G  S 
Sbjct: 20725 ISGYFLEKR---DKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSE 20781

Query: 1025  VSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE 1084
              SE +K  +  I  PGPP  ++ ++  K S+ L W  PV+ G + VTGY V++++   +E
Sbjct: 20782 PSEFYKAAD-PIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ--GEE 20838

Query: 1085  DQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKE 1143
             ++W  ++ +  ++     V  LK GV+Y FRV A+N AG G+P ++  PV A+      E
Sbjct: 20839 EEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE 20898

Query: 1144  ----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKT 1193
                       V+    +D  + + F   K  P    +W KD  +     R  +E+  + +
Sbjct: 20899 IDLDVALRTSVIAKAGEDVQVLIPF---KGRPPPTVTWRKDEKNLGSDARYSIENTDSSS 20955

Query: 1194  KMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVE 1253
              +T   +  +D G Y   + +  G   S  +  + L             T     +L V+
Sbjct: 20956 LLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVL------------DTPAACQKLQVK 21003

Query: 1254  ILEKGQVRFWMQAEKLSGNAK-VNYIFNEKE 1283
              + +G V        + G +  +NY+  +++
Sbjct: 21004 HVSRGTVTLLWDPPLIDGGSPIINYVIEKRD 21034



 Score =  202 bits (513), Expect = 3e-51
 Identities = 201/738 (27%), Positives = 302/738 (40%), Gaps = 66/738 (8%)

Query: 438   QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
             +P I W ++G+PL  S++V+   +  + TL+  +  KE  G YT+ +            V
Sbjct: 21220 KPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21279

Query: 498   FVRDADAEIEGAPAAPLD-VKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
                       G P+ P   ++  E   D +I+SW  P  +GG  I  Y I+K E    +W
Sbjct: 21280 ITL-------GPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 21332

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
                  +  +   F V  L++   Y FRVRA N+ G+                        
Sbjct: 21333 KMVCSSVAR-TTFKVPNLVKDAEYQFRVRAENRYGV------------------------ 21367

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYF-VEK 675
              S P    IIV + +     +PGPP    +   T   + L+W  P   G   +  F VEK
Sbjct: 21368 -SQPLVSSIIVAKHQFR---IPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEK 21423

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  WQ+VNT  P+    +    L EG  Y FRV   NSAG+  PS+ ++ T+    
Sbjct: 21424 KERNSILWQKVNTS-PISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSP 21482

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKG 793
             +D P  P  I  +R T   + + W         ++VGY IE    G+ +W  CN   V  
Sbjct: 21483 VDPPGTPDYIDVTRET---ITLKWNPPLRDGGSKIVGYSIEKR-QGNERWVRCNFTDVSE 21538

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAIGGGV---SPDVCPALSD 849
              ++T  GL  G  Y FR+ A NA G +S  SQ S  I  +      +    P+    L  
Sbjct: 21539 CQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLII 21598

Query: 850   EPGGLTASRGRVHEASPP--TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEEL 907
             + G     +  V     P  T+ KD   G +  K      +  LG T +     T     
Sbjct: 21599 KSGESLRIKALVQGRPVPRVTWFKD---GVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21655

Query: 908   TPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                 +     G +K++ +K K    P      I       + M L W  P   G A IT 
Sbjct: 21656 VYTVEAKNASGSAKAE-IKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITH 21714

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             Y +  RE    +     E   +A S  A K+ N  E   YQF+V+A+N  G+G P     
Sbjct: 21715 YIIEKRET-SRLAWALIEDKCEAQSYTAIKLINGNE---YQFRVSAVNKFGVGRPLDSDP 21770

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW 1087
                  ++T  VP  P   + S +  +S+ L W  P   G + +  Y ++ +E K+   +W
Sbjct: 21771 VVAQIQYT--VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS--TRW 21826

Query: 1088  -RGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE--TRPGTKEV 1144
              + +++  I     KV GL EG  Y F V A N AGVG  S ++  +       P     
Sbjct: 21827 VKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPT 21886

Query: 1145  VVNVDDDGVISLNFECDK 1162
             VV V D    +++ E  K
Sbjct: 21887 VVKVTDTSKTTVSLEWSK 21904



 Score =  201 bits (510), Expect = 6e-51
 Identities = 194/718 (27%), Positives = 295/718 (41%), Gaps = 94/718 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P++ W    + L  +  V    + +R TLT     + D G Y + +      + +S  V 
Sbjct: 22305 PKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVV 22364

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V      + G    P++V  + A     ++SW +P   GG+ I  Y ++K E GT +W  
Sbjct: 22365 VIGRPGPVTG----PIEVSSVSAES--CVLSWGEPKDGGGTEITNYIVEKRESGTTAWQL 22418

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              N + VK  +  VT L +   Y FRV + N+ G+  P   S P+ A  P           
Sbjct: 22419 VNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE-SAPIIAEHPF---------- 22466

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                              + P  PT   V   + + + + W+ P   G   I+ Y+VEK E
Sbjct: 22467 -----------------VPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKE 22509

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
               T  W + N ++P     + +  L EG  Y FR    N+AGV + SEA+   +  + +D
Sbjct: 22510 RNTILWVKEN-KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVD 22568

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIE---ASVAGSGKWEPCNNNPVKGS 794
              P  P     +R+T  S++ S        ++VGY IE    S  G G+W  CN   V  +
Sbjct: 22569 APGRPEVTDVTRST-VSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDN 22627

Query: 795   RFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG 853
              FT   L  G +Y FRV A NAAG +S+ S+ +  +  +         +  P  ++    
Sbjct: 22628 FFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR--------DEYAPPKAELDAR 22679

Query: 854   LTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQK 913
             L      +   S      DA +G KP     P      G  E+  + E V  + T     
Sbjct: 22680 LHGDLVTIRAGSDLVL--DAAVGGKPE----PKIIWTKGDKELD-LCEKVSLQYTGKRAT 22732

Query: 914   AAPQGKSKSDPLK------------------KKTDRAPPSPPCDITCLESFRDSMVLGWK 955
             A  +   +SD  K                  K  D   P P   +T     ++   L W 
Sbjct: 22733 AVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLD--SPGPCGKLTVSRVTQEKCTLAWS 22790

Query: 956   QPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEE----AYKISNLKENMVYQFQV 1011
              P + GGAEIT Y V  RE            N   V  E    +Y ++ L +N  Y F+V
Sbjct: 22791 LPQEDGGAEITHYIVERRET--------SRLNWVIVEGECPTLSYVVTRLIKNNEYIFRV 22842

Query: 1012  AAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVT 1071
              A+N  G G P           +TI  P PP   +     K+ +++QW  P   G   ++
Sbjct: 22843 RAVNKYGPGVPVESEPIVARNSFTI--PSPPGIPEEVGTGKEHIIIQWTKPESDGGNEIS 22900

Query: 1072  GYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              Y VD +E K+   +W  +N +  + +  LKV  L EG  Y FRV A+N AG  +PS+
Sbjct: 22901 NYLVDKREKKSL--RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 22956



 Score =  191 bits (486), Expect = 4e-48
 Identities = 191/741 (25%), Positives = 302/741 (40%), Gaps = 88/741 (11%)

Query: 412   DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH 471
             DV   R G+T+ +  RV   PE     P+I W + G  L   K V  +    R  L    
Sbjct: 11544 DVITVRVGQTIRILARVKGRPE-----PDITWTKEGKVLVREKRVDLIQDLPRVELQIKE 11598

Query: 472   LNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWK 531
               + D G Y I  +    + Q SA V V D        P    ++K     K+   ISW+
Sbjct: 11599 AVRADHGKYIISAKNSSGHAQGSAIVNVLDR-------PGPCQNLKVTNVTKENCTISWE 11651

Query: 532   QPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMG 591
              P  +GGS I  + ++  +     WS       K  R     L+    Y FRV A NK+G
Sbjct: 11652 NPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTK--RLIKANLLANNEYYFRVCAENKVG 11709

Query: 592   IGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATR 651
             +G       P+ A++P ++                           PG P +L + +  +
Sbjct: 11710 VGPTIETKTPILAINPIDR---------------------------PGEPENLHIADKGK 11742

Query: 652   SYVVLSWKPPG-QRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCF 710
             ++V L W+ P    G   + Y VE+   G+++W+RV+ +  +K   + +    E + Y F
Sbjct: 11743 TFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVH-KGSIKETHYMVDRCVENQIYEF 11801

Query: 711   RVRCSNSAGVGEPSEATEVTVVGD----KLDIPKAPGKIIPSRNT---DTSV------VV 757
             RV+  N  G  +  +  EV V  D     LD+  +    + + +T   +  V       V
Sbjct: 11802 RVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEV 11861

Query: 758   SWEESKDAKELV---GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             +W + KDA +L       I+   A S K+         G ++      T  S++     V
Sbjct: 11862 AWTKDKDATDLTRSPRVKIDTR-ADSSKFSLTKAKRSDGGKYVVTATNTAGSFV-AYATV 11919

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEP--GGLTASRGRVHEASPPTFQKD 872
             N        ++ + ++        VS D C    D P   G    +  + E         
Sbjct: 11920 NVLDKPGPVRNLKIVD--------VSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW 11971

Query: 873   ALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRA 932
             +   +    P    +    G   + +V    +    PP +      K+K D    K  R 
Sbjct: 11972 STYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYD----KPGR- 12026

Query: 933   PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVS 992
              P PP ++T +   ++ M + W  P+  GG  ITGY++  +E       +W   N  A+ 
Sbjct: 12027 -PDPP-EVTKVS--KEEMTVVWNPPEYDGGKSITGYFLEKKEKHS---TRWVPVNKSAIP 12079

Query: 993   EEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRK 1052
             E   K+ NL  +  YQF+V A N  G+G PS  S     ++  I  PGPP + +  +  K
Sbjct: 12080 ERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKD-PIEPPGPPTNFRVVDTTK 12138

Query: 1053  DSLVLQWKPPVHSGRTPVTGYFVDL--KEAKAKEDQ-WRGLNEAA-IKNVYLKVRGLKEG 1108
              S+ L W  PV+ G  P+ GY V++  K A A  D+ W+  N AA +      V  L E 
Sbjct: 12139 HSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDEN 12198

Query: 1109  VSYVFRVRAINQAGVGKPSDL 1129
               Y FRV A NQ G+G+P++L
Sbjct: 12199 QEYEFRVCAQNQVGIGRPAEL 12219



 Score =  191 bits (484), Expect = 7e-48
 Identities = 185/740 (25%), Positives = 303/740 (40%), Gaps = 88/740 (11%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P+ P +V  L+  K  + +SW +P  DGGS + GY+I++ E  TD W + N T +    +
Sbjct: 23960 PSNPPEV--LDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMY 24017

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGL+    Y FR+ A N +G+   S  SEPV   DP +K                   
Sbjct: 24018 TVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDK------------------- 24058

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNT 688
                     P  P +L +   ++  V L W KP    G E + Y+VE  ++G   W++ N 
Sbjct: 24059 --------PSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNK 24110

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPS 748
             E  +K  +F +  L E   Y FRV   N  G+  P        +  KL   +APG     
Sbjct: 24111 ER-IKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTKLTSGEAPGIRKEM 24167

Query: 749   RNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYI 808
             ++  T +    E ++ + ++VG  +        KW       ++  ++       G+++ 
Sbjct: 24168 KDVTTKL---GEAAQLSCQIVGRPLPDI-----KWYRFGKELIQSRKYKMSS--DGRTHT 24217

Query: 809   FRVRAVNAAGLSEYS----QDSEAIEVKAAIGGGVSPDVCPA--LSDEPGGLTASRGRVH 862
               V          Y+     +   +E  + +    +P   P   L ++  G   S  R+H
Sbjct: 24218 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLH 24277

Query: 863   EA--SPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS 920
                   P        G K     L  +S+N+        +  V + +    Q+    GK 
Sbjct: 24278 VMYIGRPVPAMTWFHGQK-----LLQNSENITIENTEHYTHLVMKNV----QRKTHAGKY 24328

Query: 921   KSDP----------LKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYV 970
             K             L  +    P  P   I      ++S V+ WK P   GG+ IT Y V
Sbjct: 24329 KVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVV 24388

Query: 971   NYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK 1030
                E  +G   +W+  +  A+S    +I NL EN  Y F+V+A N  G+  P  VS    
Sbjct: 24389 EKCEAKEGA--EWQLVS-SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVI 24445

Query: 1031  CEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGL 1090
              +      PG P     + V KDS V+ WKPP   G   +  Y+++ +E   K+++W  +
Sbjct: 24446 IKS-PFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKRE--KKQNKWISV 24502

Query: 1091  NEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET-----RPGTKEVV 1145
                 I+     V+ L EG+ Y FRV+  N  G  + S+++ P+  ++      P  KE +
Sbjct: 24503 TTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEEL 24562

Query: 1146  VNVDDDGVISLNFECDKMT--PKSEFSW---SKDYVSTEDSPRLEVESKGNKTKMTFKDL 1200
              N++     +    C K+T  PK    W    K+ ++     R++ E KG   ++    +
Sbjct: 24563 RNLNVRYQSNATLVC-KVTGHPKPIVKWYRQGKEIIADGLKYRIQ-EFKGGYHQLIIASV 24620

Query: 1201  GMDDLGIYSCDVTDTDGIAS 1220
               DD  +Y    T+  G  S
Sbjct: 24621 TDDDATVYQVRATNQGGSVS 24640



 Score =  189 bits (481), Expect = 1e-47
 Identities = 201/817 (24%), Positives = 331/817 (40%), Gaps = 114/817 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             PEI W R     +    VQ         L+  + ++ D G Y +++      +  SA+V 
Sbjct: 17682 PEITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSK--SAFVT 17737

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V+  D      P  P ++   E  KD   + W+ P +DGG+ +  Y IDK E    +++ 
Sbjct: 17738 VKVLDT-----PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYAN 17792

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              +    K + F V  L EG  Y FRV A N+ G+G P    + V A +P           
Sbjct: 17793 VSSKCSKTS-FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP----------- 17840

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                                P PP  +++T+ +++   L W+ P   G   ++ Y VE   
Sbjct: 17841 -------------------PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 17881

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
              GTE W  V      K     +  L+ G+ Y FRV+  N  G  +P     V V+   L 
Sbjct: 17882 KGTEKWSIVAES---KVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP-RVLGVPVIAKDLT 17937

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGK----WEPCNNNPVKG 793
             I   P   +P          S +  +D K      IE  V G  +    W   +  P+K 
Sbjct: 17938 IQ--PSLKLPFNT------YSIQAGEDLK------IEIPVIGRPRPNISWVK-DGEPLKQ 17982

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG 853
             +    +   T  S +  ++  N     +Y+       V A    G + +    +  E  G
Sbjct: 17983 TT-RVNVEETATSTVLHIKEGNKDDFGKYT-------VTATNSAGTATENLSVIVLEKPG 18034

Query: 854   LTASRGRVHEAS---------PPTFQKDALLGSK-PNKPSLPSSSQNLGQTEVSKVSETV 903
                   R  E S         PP +     + +    K    +++ ++    V++ +  +
Sbjct: 18035 PPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKI 18094

Query: 904   QEELTPPPQKA---APQGKSKSDPLKKKT-----DRAPPSPPCDITCLESFRDSMVLGWK 955
              +  T    +    A     KS PL  K          P PP         +D M++ W 
Sbjct: 18095 TKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWH 18154

Query: 956   QPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMN 1015
             +P   GG +I GY++  +E    +   W + N   + +  +K + L E + Y+F+V+A N
Sbjct: 18155 EPVNDGGTKIIGYHLEQKEKNSIL---WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAEN 18211

Query: 1016  MAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFV 1075
             + G+G PS VSECF   +     PG P ++    + ++++ L+WK P + G + +TGY V
Sbjct: 18212 IVGIGKPSKVSECFVARD-PCDPPGRPEAI---VITRNNVTLKWKKPAYDGGSKITGYIV 18267

Query: 1076  DLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAG-VGKPSDLAGPVV 1134
             + K+    + +W   +   +      V GL E   Y FRV A N AG   +PSD +G + 
Sbjct: 18268 EKKD--LPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAIT 18325

Query: 1135  AETR---------PGTKEV-VVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTED-SPR 1183
             A            P  K+V VV+  +  V+  +    +  P  +  WSKD    E+ + R
Sbjct: 18326 ARDEIDAPNASLDPKYKDVIVVHAGETFVLEADI---RGKPIPDVVWSKDGKELEETAAR 18382

Query: 1184  LEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
             +E++S   KT +  KD    D G Y   +++  G  S
Sbjct: 18383 MEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18419



 Score =  188 bits (477), Expect = 4e-47
 Identities = 155/528 (29%), Positives = 237/528 (44%), Gaps = 49/528 (9%)

Query: 638   PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
             P PP +L VTE T+  V ++W+PP   G   I  Y VEK EA  +++  V T     S  
Sbjct: 16662 PSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNS-- 16719

Query: 697   FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
             + +  L EG SY FRV   N  G+G P++  +   V +   +P+ PGKI     T  SV 
Sbjct: 16720 WKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE---VPQPPGKITVDDVTRNSVS 16776

Query: 757   VSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             +SW   E     +++ Y +E     S KW  C    VK  +     L  G+ Y+FRV AV
Sbjct: 16777 LSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEYLFRVVAV 16834

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDAL 874
             N  G S+    +  I  K  +   + PDV PA S      +   G+  +   P       
Sbjct: 16835 NEKGRSDPRSLAVPIVAKDLV---IEPDVKPAFSS----YSVQVGQDLKIEVP------- 16880

Query: 875   LGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-------------K 921
             +  +P KP++  +   L   + ++++ T   +LT    K   +                K
Sbjct: 16881 ISGRP-KPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQK 16939

Query: 922   SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPG 981
             +  ++  T   P  P   +   +   +S+ L W  P   GG +IT Y V  R+    V  
Sbjct: 16940 TASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTV-- 16997

Query: 982   KWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGP 1041
              W   +   V+    K++ LK    YQF++ A N    G   A+       ++    PGP
Sbjct: 16998 -WDVVSA-TVARTTLKVTKLKTGTEYQFRIFAENR--YGQSFALESDPIVAQYPYKEPGP 17053

Query: 1042  PHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLK 1101
             P +   + + KDS+V+QW  PV++G +PV GY ++ KE  +    W  +N+  I +   K
Sbjct: 17054 PGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNS--ILWTKVNKTIIHDTQFK 17111

Query: 1102  VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVV 1146
              + L+EG+ Y FRV A N  GVGK S  +   VA      PGT E ++
Sbjct: 17112 AQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIM 17159



 Score =  179 bits (455), Expect = 2e-44
 Identities = 211/823 (25%), Positives = 315/823 (38%), Gaps = 119/823 (14%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRV--RMGEYYEQYSAY 496
             P++ W + G+     K    L     A L   +  ++D G Y++ +    GE     + +
Sbjct: 12264 PKVTWRKVGIDNVVRKGQVDLVD-TMAFLVIPNSTRDDSGKYSLTLVNPAGEK----AVF 12318

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             V VR  D      P    D+K  +  K    +SW  P  DGGS +  Y ++K E    +W
Sbjct: 12319 VNVRVLDT-----PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW 12373

Query: 557   SQCNDTP-VKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKS 615
             S    TP VK   F VT L+ G  Y FRV AVN+ G G P+ V +PV A DP  +     
Sbjct: 12374 STV--TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE----- 12426

Query: 616   RPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEK 675
                                   P PP  L VTE T++   L+W PP + G   I  ++  
Sbjct: 12427 ----------------------PDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITS 12464

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
                  +   R      VK     +  L EGK Y FRV   N+ GV  P EA  V    ++
Sbjct: 12465 YREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQ 12524

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSG----KWEPCNNNPV 791
             L  PK    ++P + T           K  K+L    IEA V G      KW+   +  V
Sbjct: 12525 LLPPKI---LMPEQIT----------IKAGKKL---RIEAHVYGKPHPTCKWKKGEDEVV 12568

Query: 792   KGSRFTCHGLVTGQSYIFRVRAVNAAGL----SEYSQDSEAIEVKAAIGGGVSPDVCPA- 846
               S    H   +    I +      +G     +E S  ++  ++K  +     P   P  
Sbjct: 12569 TSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFD 12628

Query: 847   LSD--------------EPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLG 892
             +SD              E GG   +   V +           L S   K S        G
Sbjct: 12629 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASV-TKTSCRVGKLIPG 12687

Query: 893   QTEVSKVSET----VQEELTPPPQKAA-PQGKSKSDPLKKKTDRAPPSPPCDITCLESFR 947
             Q  + +V       + E LT P   A  P G               PS P +    +  +
Sbjct: 12688 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGV--------------PSEPKNARVTKVNK 12733

Query: 948   DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY 1007
             D + + W +PD  GG+ I GY +  +E    +   W +AN   V    Y  + L E + Y
Sbjct: 12734 DCIFVAWDRPDSDGGSPIIGYLIERKERNSLL---WVKANDTLVRSTEYPCAGLVEGLEY 12790

Query: 1008  QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 1067
              F++ A+N AG   PS  +E +      +  PG P  +   +V K ++ L W  P H G 
Sbjct: 12791 SFRIYALNKAGSSPPSKPTE-YVTARMPVDPPGKPEVI---DVTKSTVSLIWARPKHDGG 12846

Query: 1068  TPVTGYFVDLKEAKAKEDQWRGLNEAA--IKNVYLKVRGLKEGVSYVFRVRAINQAGVGK 1125
             + + GYFV+    K   D+W   N A   I        GL+E   Y FR  A     +  
Sbjct: 12847 SKIIGYFVEA--CKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISP 12904

Query: 1126  PSDLAGPV--VAETRPGTKEVVVNVDDDGVISLNFE-CDKMT----PKSEFSWSKDYVST 1178
             PS+ + PV  +AE  P   ++ V +     +      C   T    P    SW KD    
Sbjct: 12905 PSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLL 12964

Query: 1179  EDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
             + +  +++  + N   +    +   D G Y+    ++ G  S+
Sbjct: 12965 KPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSA 13007



 Score =  177 bits (450), Expect = 6e-44
 Identities = 186/778 (23%), Positives = 306/778 (39%), Gaps = 86/778 (11%)

Query: 465   ATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKD 524
             +TLT  + N+ D G YT+ V      +  +  V V D        P  P+  K  +  + 
Sbjct: 22039 STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPG-----PPGPITFK--DVTRG 22091

Query: 525   YIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRV 584
                + W  P +DGG+ I  Y ++K E    SW   ++   +   F V  L EG  Y FRV
Sbjct: 22092 SATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQI-FKVNDLAEGVPYYFRV 22150

Query: 585   RAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDL 644
              AVN+ G+G P  + EP+ A                       TE+       P PP  L
Sbjct: 22151 SAVNEYGVGEPYEMPEPIVA-----------------------TEQ-------PAPPRRL 22180

Query: 645   SVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLA 703
              V + ++S  VL+W  P   G   I  Y +E  + G++ W         K   F +  L 
Sbjct: 22181 DVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH---TKQLTFTVERLV 22237

Query: 704   EGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK-----LDIPKAPGKIIPSRNTDTSVVVS 758
             E   Y FRV+  N AG  EP EA    ++ +       D+     ++I  +      +  
Sbjct: 22238 EKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDV 22297

Query: 759   WEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAG 818
                 + A ++     E  +  + +           +  T    + G S  + +   N AG
Sbjct: 22298 PISGRPAPKVTWKLEEMRLKETDRVSITTTKD--RTTLTVKDSMRGDSGRYFLTLENTAG 22355

Query: 819   LSEYSQDSEAIEVKAAIGG-----GVSPDVCPALSDEP--GGLTASRGRVHEASPPTFQK 871
             +  +S     I     + G      VS + C     EP  GG T     + E        
Sbjct: 22356 VKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRE----- 22410

Query: 872   DALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-KSDPLKKKTD 930
                  S      L +SS    Q +V+ +++ ++       +      K  +S P+  +  
Sbjct: 22411 -----SGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHP 22465

Query: 931   RAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKA 990
               PPS P          ++M + W++P   GG++I GY+V  +E    +   W + N   
Sbjct: 22466 FVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTIL---WVKENKVP 22522

Query: 991   VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEV 1050
               E  YK++ L E + YQF+  A+N AG+   S  S     +   +  PG P   + ++V
Sbjct: 22523 CLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQN-PVDAPGRP---EVTDV 22578

Query: 1051  RKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKED-QWRGLNEAAIKNVYLKVRGLKEGV 1109
              + ++ L W  P + G + V GY ++ K      D +W   N   + + +  V  L EG 
Sbjct: 22579 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22638

Query: 1110  SYVFRVRAINQAGV-GKPSDLAGPVVA--ETRPGTKEVVVNVDDDGVISLNFECDKM--- 1163
             +Y FRV A N AGV  K S+  GPV    E  P   E+   +  D ++++    D +   
Sbjct: 22639 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD-LVTIRAGSDLVLDA 22697

Query: 1164  ----TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
                  P+ +  W+K     +   ++ ++  G +     K     D G Y+  V +  G
Sbjct: 22698 AVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22755



 Score =  167 bits (422), Expect = 1e-40
 Identities = 156/528 (29%), Positives = 237/528 (44%), Gaps = 54/528 (10%)

Query: 637  VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFV-EKCEAGTENWQRVNTELPVKSP 695
            VPGP  DL      R   +L+W  P   G   I  F+ E+ +A    W++     P+++ 
Sbjct: 8824 VPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ-----PIETE 8878

Query: 696  RFA--LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDT 753
            R    +  L EG+ Y FRV   N  G G P E   +  V D L  P +P ++  +  T +
Sbjct: 8879 RSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAV-DPLGPPTSPERLTYTERTKS 8937

Query: 754  SVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRV 811
            ++ + W+E  S     + GY IE        +E  N      + F    L   Q Y FRV
Sbjct: 8938 TITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRV 8997

Query: 812  RAVNAAGLSEYS-------QDSEA---IEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV 861
            +AVN  G SE S       QD E    I+++ ++ G    D     + EP  + A    V
Sbjct: 8998 KAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG----DTIKVKAGEPVHIPAD---V 9050

Query: 862  HEASPPTFQ--KDALLGSKPNKP---SLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAP 916
                 P  +  K+  +  KP      +    S++  +TE+S      +++ T     +  
Sbjct: 9051 TGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNR 9110

Query: 917  QGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVI 976
             G    +   +  DR  PSPP ++   +   +S  L W  P   GG+EIT Y ++ R+  
Sbjct: 9111 LGSVFRNVHVEVYDR--PSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDA- 9167

Query: 977  DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
                 +W E    AV E+ Y I  L  N  Y+F+V A+N  G+       EC K ++  I
Sbjct: 9168 SRKKAEWEEVTNTAV-EKRYGIWKLIPNGQYEFRVRAVNKYGIS-----DEC-KSDKVVI 9220

Query: 1037 A----VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNE 1092
                 +PGPP   K     K S+++ W PP+ +G +P+TGY+++ +E  +    W  ++ 
Sbjct: 9221 QDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSP--YWSRVSR 9278

Query: 1093 AAIKNVYLK-----VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA 1135
            A I  V LK     V  L EGV Y FR  AIN AG+G PS+ + P VA
Sbjct: 9279 APITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVA 9326



 Score =  157 bits (397), Expect = 8e-38
 Identities = 201/762 (26%), Positives = 300/762 (39%), Gaps = 125/762 (16%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESR-YGM------HTLEINGCDF 344
             E  +L C I G P P + WY+           GK +I+SR Y M      HTL +   + 
Sbjct: 24176 EAAQLSCQIVGRPLPDIKWYRF----------GKELIQSRKYKMSSDGRTHTLTVMTEEQ 24225

Query: 345   EDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFE 404
             ED   Y   A N  GE+   + ++++         +FH G    PL              
Sbjct: 24226 EDEGVYTCIATNEVGEVETSSKLLLQA------TPQFHPG---YPLK------------- 24263

Query: 405   IHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGER 464
                 +K+   +G  G T+ L    +  P      P + W+     L  S+ + T+ + E 
Sbjct: 24264 ----EKY---YGAVGSTLRLHVMYIGRPV-----PAMTWFHGQKLLQNSENI-TIENTEH 24310

Query: 465   AT-LTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDA--DAEIEGAPAAPLDVKCLEA 521
              T L   ++ +        +   G+Y  Q S      DA  D EI+  P  P     +EA
Sbjct: 24311 YTHLVMKNVQR--------KTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEA 24362

Query: 522   N-KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSY 580
               K+  +ISWK PA DGGS I  Y ++KCE    +  Q   + +      +  L E   Y
Sbjct: 24363 LLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGY 24422

Query: 581   IFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGP 640
              FRV A N  GI  P  VS  V    P EK                           PG 
Sbjct: 24423 YFRVSAQNTFGISDPLEVSSVVIIKSPFEK---------------------------PGA 24455

Query: 641   PTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFAL 699
             P   ++T  T+   V++WKPP   G   I  Y++EK E     W  V TE  ++   F++
Sbjct: 24456 PGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTE-EIRETVFSV 24514

Query: 700   FDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP-KAPGKIIPSRNTD----TS 754
              +L EG  Y FRV+C N  G  E SE +E   +  K D+P +AP      RN +    ++
Sbjct: 24515 KNLIEGLEYEFRVKCENLGGESEWSEISE--PITPKSDVPIQAPHFKEELRNLNVRYQSN 24572

Query: 755   VVVSWEESKDAKELVGYYIEAS--VAGSGKWEPCNNNPVKGS--RFTCHGLVTGQSYIFR 810
               +  + +   K +V +Y +    +A   K+        KG   +     +    + +++
Sbjct: 24573 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKY---RIQEFKGGYHQLIIASVTDDDATVYQ 24629

Query: 811   VRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQ 870
             VRA N  G S     S  +EV A I         P   +  G + A RG V     P   
Sbjct: 24630 VRATNQGG-SVSGTASLEVEVPAKIH-------LPKTLEGMGAVHALRGEVVSIKIPFSG 24681

Query: 871   K-DALLGSKPNKPSLPSSSQN---LGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLK 926
             K D ++  +  +  + ++      + ++  S V     E           + +   D   
Sbjct: 24682 KPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKT 24741

Query: 927   KKTDRAP-PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWRE 985
              + D A  P PP  +   +  RDS+ L W +P   GG++IT Y V   E       +W  
Sbjct: 24742 VELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV---EKCATTAERW-- 24796

Query: 986   ANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
               V    E  Y + NL     YQF+V A N  GL  PS  SE
Sbjct: 24797 LRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSE 24838



 Score =  153 bits (387), Expect = 1e-36
 Identities = 143/539 (26%), Positives = 230/539 (42%), Gaps = 61/539 (11%)

Query: 637  VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFV-EKCEAGTENWQRVNTELPVKSP 695
            +PGP  D+  ++ T+S   L+W+PP   G   I+++V E+ EAG        T +PV S 
Sbjct: 8107 LPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRR------TYIPVMSG 8160

Query: 696  R----FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNT 751
                 + + DL     Y FRV+  N  G GE  E     +  D    P  P  +     T
Sbjct: 8161 ENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPT 8220

Query: 752  DTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIF 809
              ++ ++W+        +++GY IE    G  +W+ CN + V    +T  GL  G+ Y F
Sbjct: 8221 AEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQF 8280

Query: 810  RVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVC--PALSDEPGGLTASRGRVHEASPP 867
            RVRA NAAG+SE    S A     A+    +P V    +L  + G   A    +  +  P
Sbjct: 8281 RVRAENAAGISE---PSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYP 8337

Query: 868  TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEE---LTPPPQKAAPQGKSKSDP 924
            T     +   K     +P   +      V +    VQEE   + P  Q+ +     K + 
Sbjct: 8338 T-----ITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 8392

Query: 925  ----------------LKKKTDRAPPSPPCDITCLES--------FRD----SMVLGWKQ 956
                            +K + D      PC ++ L++        F D    S++  W+ 
Sbjct: 8393 QLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEP 8452

Query: 957  PDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNM 1016
            P   GG+EI  Y +  ++     P          +    Y ++ L E   Y F+V A N 
Sbjct: 8453 PLDDGGSEIINYTLEKKDKTK--PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8510

Query: 1017 AGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVD 1076
             G G P  VS+    ++     P  P      +V  +S++++W  P  +G +P+ GY+++
Sbjct: 8511 FGPG-PPCVSKPLVAKD-PFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNG-SPILGYWLE 8567

Query: 1077 LKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA 1135
             +E  +    W  +N++ +  +   V GL EG++YVFRV A N AG GK S  + P  A
Sbjct: 8568 KREVNS--THWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTA 8624



 Score =  153 bits (386), Expect = 2e-36
 Identities = 113/372 (30%), Positives = 180/372 (48%), Gaps = 30/372 (8%)

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
             +S P+       PP PP         +DSMV+ W +P   GG EI GY +  R+  +GV 
Sbjct: 18517 ESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDK-EGV- 18574

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
              +W + N K +++   +++ L E   Y+F+VAA N AG+G PS  S  ++  +  +  PG
Sbjct: 18575 -RWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD-ALYPPG 18632

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVY 1099
             PP + K ++  + S+ L W  P++ G  PV GY V++KEA A  D+W        ++   
Sbjct: 18633 PPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAA--DEWTTCTPPTGLQGKQ 18690

Query: 1100  LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN-- 1157
               V  LKE   Y FR+ AIN  GVG+P+ L G VVA+ R    E+ ++ D   V+ L   
Sbjct: 18691 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18750

Query: 1158  -----FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
                  F   K  P+ E  W K      D  ++EV S  + T +   ++   D G Y+  +
Sbjct: 18751 ATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLVIDNVTRFDSGRYNLTL 18808

Query: 1213  TDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGN 1272
              +  G  ++++       R+L        P+ PV   L +  ++K  V    +   + G 
Sbjct: 18809 ENNSGSKTAFV-----NVRVL------DSPSAPV--NLTIREVKKDSVTLSWEPPLIDGG 18855

Query: 1273  AKV-NYIFNEKE 1283
             AK+ NYI  ++E
Sbjct: 18856 AKITNYIVEKRE 18867



 Score =  152 bits (385), Expect = 2e-36
 Identities = 165/617 (26%), Positives = 249/617 (40%), Gaps = 104/617 (16%)

Query: 478  GLYTIRVRMGEYY----EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQP 533
            G Y  RVR    Y    E  S  V ++D    + G P  P   K L   K  +++SW  P
Sbjct: 9195 GQYEFRVRAVNKYGISDECKSDKVVIQDP-YRLPGPPGKP---KVLARTKGSMLVSWTPP 9250

Query: 534  AVDGGSPILGYFIDKCEVGTDSWSQCNDTPV-----KFARFPVTGLIEGRSYIFRVRAVN 588
              +GGSPI GY+++K E G+  WS+ +  P+     K   F V  L+EG  Y FR  A+N
Sbjct: 9251 LDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 9310

Query: 589  KMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTE 648
              GIG PS  S+P  A DP                              PGPP+   V +
Sbjct: 9311 AAGIGPPSEPSDPEVAGDPI---------------------------FPPGPPSCPEVKD 9343

Query: 649  ATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT-ELPVKSPRFALFDLAEGK 706
             T+S + L WKPP + G   I  Y VE  E GT +W+RVN  +  + +    + +L E +
Sbjct: 9344 KTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELR 9403

Query: 707  SYCFRVRCSNSAGVGEPSEATE-----------------------VTVVGDKLDIPKAPG 743
             Y FRV+  N AG  EPS+ T                        V   G ++ IP    
Sbjct: 9404 KYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPA--- 9460

Query: 744  KIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVT 803
             +I  R T  S   SWE    AK+ +   +   +    + E   N+ V      C    T
Sbjct: 9461 -VIKGRPTPKS---SWEFDGKAKKAMKDGVH-DIPEDAQLETAENSSVIIIP-ECKRSHT 9514

Query: 804  GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHE 863
            G+   + + A N AG     Q +    VK     G   D+   +SD    +T    R+  
Sbjct: 9515 GK---YSITAKNKAG-----QKTANCRVKVMDVPGPPKDL--KVSD----ITRGSCRLSW 9560

Query: 864  ASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKS- 922
              P     D + G    K ++   +      +    +  V + L+        + +++  
Sbjct: 9561 KMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFG 9620

Query: 923  -----DPLKKKTDRAP---PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYR- 973
                 + +++ T R P   P PP  +      ++++ L WK P   GG+ +T Y V    
Sbjct: 9621 IGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLA 9680

Query: 974  -EVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCE 1032
             +        WR+ N + V E  + + +L E   Y+F+V A+N AG+  PSA      C+
Sbjct: 9681 WDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQ 9740

Query: 1033 EWTIAVPGPPHSLKCSE 1049
                  P  P S+   E
Sbjct: 9741 R-----PDMPPSIDLKE 9752



 Score =  150 bits (380), Expect = 8e-36
 Identities = 169/756 (22%), Positives = 290/756 (38%), Gaps = 92/756 (12%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             T+    +++L  S++G P P +TW K  + +   A     II++      L ++  +  D
Sbjct: 23085 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA-----IIDTTESYSLLIVDKVNRYD 23139

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRF-HAGASTMPLSFGVTPYGYASRFEI 405
               +Y   A N  G+ SA   V V    G     +       ++ +++ +      +    
Sbjct: 23140 AGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNN 23199

Query: 406   HFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERA 465
             +  +K + +  R  +T++  C   +             YR          +  L  G   
Sbjct: 23200 YIVEKREAAM-RAFKTVTTKCSKTL-------------YR----------ISGLVEG--- 23232

Query: 466   TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
               T  +     E +Y I    GE  E   A +        +   P  P  ++ ++  K  
Sbjct: 23233 --TMYYFRVLPENIYGI----GEPCETSDAVL--------VSEVPLVPAKLEVVDVTKST 23278

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
             + ++W++P  DGGS + GY ++ C+ GT+ W +            VT L EG  Y+FR+R
Sbjct: 23279 VTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23338

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             A N+ G+  P      V   D      L+  P+       + T  + +  +  G P +L 
Sbjct: 23339 AQNEKGVSEPRETVTAVTVQD------LRVLPTID-----LSTMPQKTIHVPAGRPVELV 23387

Query: 646   VTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEG 705
             +  A R     SW   G +  E                +RV  E   K  +  + +    
Sbjct: 23388 IPIAGRPPPAASWFFAGSKLRES---------------ERVTVETHTKVAKLTIRETTIR 23432

Query: 706   KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESK 763
              +  + +   N  G    SE  +V ++ DK   P  P KI       TS+ +SWE  E  
Sbjct: 23433 DTGEYTLELKNVTGT--TSETIKVIIL-DKPGPPTGPIKI--DEIDATSITISWEPPELD 23487

Query: 764   DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823
                 L GY +E   A    W P + + V  S F    L  G  Y+FRV A N  G+  Y 
Sbjct: 23488 GGAPLSGYVVEQRDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYL 23546

Query: 824   QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTAS------RGRVHEASPPTFQKDALLGS 877
             Q SE IE +++I     P+          G+T +       G          +K+     
Sbjct: 23547 Q-SEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADR 23605

Query: 878   KPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPP 937
                   +P +      T +++  E  +  +T    + + +    S P+      APP  P
Sbjct: 23606 WVRVNKVPVTMTRYRSTGLTEGLE-YEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKP 23664

Query: 938   CDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYK 997
              +    ++ R S+ L W  P+  GG+++TGY +  ++V      +W + N        Y 
Sbjct: 23665 QNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQ---HEWTKCNTTPTKIREYT 23721

Query: 998   ISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE 1033
             +++L +   Y+F+V A N  G G P+ V    K  E
Sbjct: 23722 LTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTE 23757



 Score =  145 bits (366), Expect = 3e-34
 Identities = 132/461 (28%), Positives = 195/461 (42%), Gaps = 55/461 (11%)

Query: 367   VVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKF-DVSFGREGETMSLG 425
             V+ +   G F E    +GA        +T            D K+ DV     GET  L 
Sbjct: 18305 VIARNAAGNFSEPSDSSGA--------ITARDEIDAPNASLDPKYKDVIVVHAGETFVLE 18356

Query: 426   CRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG-ERATLTFSHLNKEDEGLYTIRV 484
               +   P      P++ W ++G  L  +     + S  ++ TL      + D G Y +++
Sbjct: 18357 ADIRGKPI-----PDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKL 18411

Query: 485   RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGY 544
                   +     V V D      G P  PL V  + A K Y+  +W  P  DGG+ I  Y
Sbjct: 18412 SNVGGTKSIPITVKVLDRP----GPPEGPLKVTGVTAEKCYL--AWNPPLQDGGANISHY 18465

Query: 545   FIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAA 604
              I+K E    SW+Q + T V+   + VT L+ G  YIFRV AVNK GIG P   S PV A
Sbjct: 18466 IIEKRETSRLSWTQVS-TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE-SGPVTA 18523

Query: 605   LDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSW-KPPGQ 663
              +P +                            PGPP+   V+  T+  +V++W +P   
Sbjct: 18524 CNPYKP---------------------------PGPPSTPEVSAITKDSMVVTWARPVDD 18556

Query: 664   RGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEP 723
              G E   Y +EK +     W + N +  +   R  +  L EG SY FRV   N+AGVGEP
Sbjct: 18557 GGTEIEGYILEKRDKEGVRWTKCNKKT-LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEP 18615

Query: 724   SEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSG 781
             SE +      D L  P  P     +  + +SV ++W +        + GY +E   A + 
Sbjct: 18616 SEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAAD 18675

Query: 782   KWEPCN-NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSE 821
             +W  C     ++G +FT   L     Y FR+ A+N+ G+ E
Sbjct: 18676 EWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGE 18716



 Score =  145 bits (365), Expect = 4e-34
 Identities = 179/719 (24%), Positives = 290/719 (40%), Gaps = 83/719 (11%)

Query: 638  PGPPTDLSVTEATRSYVVLSWKPP-GQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPR 696
            PGPP +    +  ++ V+  W+PP    G E I Y +EK +    + + +     ++  +
Sbjct: 8430 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCK 8489

Query: 697  FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
            +++  L EGK Y FRVR  N  G G P   ++  V  D    P AP K I    T  S++
Sbjct: 8490 YSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSML 8548

Query: 757  VSWEESKD-AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVN 815
            V W E KD    ++GY++E     S  W   N + +   +    GL+ G +Y+FRV A N
Sbjct: 8549 VKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAEN 8608

Query: 816  AAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDA-L 874
            AAG  ++S  S+       I     P   P ++D     T+S     E  PP F     +
Sbjct: 8609 AAGPGKFSPPSDPKTAHDPISPPGPP--IPRVTD-----TSSTTIELEWEPPAFNGGGEI 8661

Query: 875  LGSKPNKPSLPSSSQN--------LGQTEVSKVSETVQEELTPPPQKAAPQGK-SKSDPL 925
            +G   +K  + ++  +        + Q  V ++ E    +L      AA +G   ++ P+
Sbjct: 8662 VGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPV 8721

Query: 926  KKKTDRAPPSPPCDITCLESFR---------DSMVLGWKQPDKIGGAEITGYYVNYREVI 976
                 + PP+   D++     +          ++V G   P K+   E  G     R VI
Sbjct: 8722 TVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKE-EGELDKDRVVI 8780

Query: 977  DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
            D         NV   SE   K +  K++  Y   + A N  G    +A  E F       
Sbjct: 8781 D---------NVGTKSELIIKDALRKDHGRYV--ITATNSCGSKFAAARVEVFD------ 8823

Query: 1037 AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIK 1096
             VPGP   LK     +   +L W  P   G + +TG+ ++ K+AK     WR   E   +
Sbjct: 8824 -VPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM--HTWRQPIET--E 8878

Query: 1097 NVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG----TKEVVVNVDDDG 1152
                 + GL EG  Y FRV A N+ G G P ++ GP++A    G     + +        
Sbjct: 8879 RSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEI-GPILAVDPLGPPTSPERLTYTERTKS 8937

Query: 1153 VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
             I+L+++  +    S            D P  E  +K      +F    +D+  +Y   V
Sbjct: 8938 TITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRV 8997

Query: 1213 TDTDGIASS-------YLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQ 1265
               + I  S        +I ++E+   + L    +  T+ VK+   V I           
Sbjct: 8998 KAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHI----------- 9046

Query: 1266 AEKLSG--NAKVNYIFNEKEIFEGPK-----YKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
               ++G    K+ +  NE  + E P       K  + R+    E+ + K   ED+GTYT
Sbjct: 9047 PADVTGLPMPKIEWSKNE-TVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYT 9104



 Score =  139 bits (351), Expect = 2e-32
 Identities = 139/561 (24%), Positives = 228/561 (40%), Gaps = 59/561 (10%)

Query: 510  PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
            P  P+DV+      + + I+WK P  DGGS I+GY I+K   G + W +CN+  V    +
Sbjct: 8208 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8267

Query: 570  PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
               GL EG+ Y FRVRA N  GI  PSR + P  A+DP +  ++  R S     ++   +
Sbjct: 8268 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSL----EVKRGD 8323

Query: 630  EEPSEGIVPGPP-------TDLSV---TEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAG 679
            E   +  + G P        D +V    E  +    L  +  G+   E            
Sbjct: 8324 EIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLS 8383

Query: 680  TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 739
             +N ++  ++L V+       D        + ++  N  G+ +      V      LD P
Sbjct: 8384 IDNSKKGESQLRVR-------DSLRPDHGLYMIKVENDHGIAKAPCTVSV------LDTP 8430

Query: 740  KAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEA--SVAGSGKWEPCNNNPVKGSR 795
              P   +      TSV+  WE   D    E++ Y +E         +W    +  ++  +
Sbjct: 8431 GPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTST-LRHCK 8489

Query: 796  FTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLT 855
            ++   L+ G+ Y+FRVRA N  G       S+ +  K   G   +PD  P + D      
Sbjct: 8490 YSVTKLIEGKEYLFRVRAENRFGPGPPCV-SKPLVAKDPFGPPDAPDK-PIVED-----V 8542

Query: 856  ASRGRVHEASPPTFQKDALLGSKPNKPSLPS--------SSQNLGQTEVSKVSETVQEEL 907
             S   + + + P      +LG    K  + S        S  N  +  V  + E +    
Sbjct: 8543 TSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVF 8602

Query: 908  TPPPQKAAPQGK--SKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEI 965
                + AA  GK    SDP       +PP PP      ++   ++ L W+ P   GG EI
Sbjct: 8603 RVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEI 8661

Query: 966  TGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAV 1025
             GY+V+ + V      +W     K +    Y +  ++E   Y+ +V+A+N AG G P   
Sbjct: 8662 VGYFVDKQLV---GTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPG-- 8716

Query: 1026 SECFKCEEWTIAVPGPPHSLK 1046
                + +  T+A P  P +++
Sbjct: 8717 ----ETQPVTVAEPQEPPAVE 8733



 Score =  134 bits (337), Expect = 7e-31
 Identities = 227/973 (23%), Positives = 378/973 (38%), Gaps = 127/973 (13%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFI-----DKCEVGTDSWSQCNDTPV 564
             P  P+ +K     K+ + +SWK P  DGGSP+  Y +     D      ++W QCN   V
Sbjct: 9640  PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDV 9699

Query: 565   KFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQ 624
             +  +F V  L+EG  Y FRV+AVN  G      VS+P A + P +  R    PS     +
Sbjct: 9700  EELQFTVEDLVEGGEYEFRVKAVNAAG------VSKPSATVGPCDCQRPDMPPSID-LKE 9752

Query: 625   IIVTEEEPSEGIV---PGPPTDLSVTEATRSYVVLSW-KPPGQR--GHEGIMYFVEKCEA 678
              +  EE  +  IV    G P           +  L+W K P ++    E ++Y       
Sbjct: 9753  FMEVEEGTNVNIVAKIKGVP-----------FPTLTWFKAPPKKPDNKEPVLYDT----- 9796

Query: 679   GTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDI 738
                    VN  +   +    +       +  + +   N+  +G  S+   + V+G +   
Sbjct: 9797  ------HVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNN--LGTASKEMRLNVLG-RPGP 9847

Query: 739   PKAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRF 796
             P  P K   S + D  + +SW   KD    ++  Y IE   A    W   ++ P K   +
Sbjct: 9848  PVGPIK-FESVSAD-QMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP-KECTY 9904

Query: 797   TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTA 856
             T   L+ G  Y+FR+ A N  G+ E   DSE    +       +PD     S     +T 
Sbjct: 9905  TIPKLLEGHEYVFRIMAQNKYGIGE-PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTV 9963

Query: 857   S--RGRVHEASPPT----FQKDALLGSKPNKPSLPSSSQNLGQT-EVSKVSETVQEELTP 909
             +         SP T      KD            P  +  LG + +V+ + E    +   
Sbjct: 9964  NWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRV 10023

Query: 910   PPQKAAPQGKSK--SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                 AA  G +   SDP   +   APP PP      +  + S  L W  P K GG+++TG
Sbjct: 10024 YAINAAGVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTG 10082

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             Y V Y+E  +G   +W +   K V      ++ LKE   Y+F+V A+N+AG+G P  V++
Sbjct: 10083 YIVEYKE--EG-KEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD 10139

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVH-----SGRTPVTGYFVDLKEAKA 1082
               + ++  ++   P   L  S   +D +V+     +      SG+ P T   V     + 
Sbjct: 10140 VIEMKDRLVS---PDLQLDASV--RDRIVVHAGGVIRIIAYVSGKPPPT---VTWNMNER 10191

Query: 1083  KEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS------DLAGPVVAE 1136
                Q   +   AI +  + ++  +     V+ + A N+AG  K +      D+ GPV   
Sbjct: 10192 TLPQEATIETTAISS-SMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPV--- 10247

Query: 1137  TRPGTKEVVVNVDDDGVISLNF--ECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTK 1194
                GT  +  N+ ++      F  E D  +P + +   K     E   R         T+
Sbjct: 10248 ---GTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEK----RESDRRAWTPVTYTVTR 10300

Query: 1195  MTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEI 1254
                   G+     Y   +   + I     ++  E    L +      P  P   +L V+ 
Sbjct: 10301 QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSE---ALVIREPITVPERP--EDLEVKE 10355

Query: 1255  LEKGQVRFWMQAEKLSGNAK-VNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDE 1313
             + K  V       K  G ++ +NY+   + I      K H   N  ++         ++ 
Sbjct: 10356 VTKNTVTLTWNPPKYDGGSEIINYVLESRLI---GTEKFHKVTNDNLLSRKYTVKGLKEG 10412

Query: 1314  GTYTFQLQ------DGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWE 1367
              TY +++        GK +  +  +   D         +F+ +  IR  G  F       
Sbjct: 10413 DTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIR-VGEAFA------ 10465

Query: 1368  VTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKK--DAGI 1425
             +TG  +   K KV+         W+KDE ++  D++   K    TL + +   K  D+G 
Sbjct: 10466 LTGRYSGKPKPKVS---------WFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGK 10516

Query: 1426  YEVILKDDRGKDK 1438
             Y V++++  G  K
Sbjct: 10517 YCVVVENSTGSRK 10529



 Score =  131 bits (330), Expect = 5e-30
 Identities = 219/1039 (21%), Positives = 387/1039 (37%), Gaps = 164/1039 (15%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             T+    ++ L  ++ G PEP++ W K    +++     K  ++      T  I  CD  D
Sbjct: 22686 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCE---KVSLQYTGKRATAVIKFCDRSD 22742

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYK-----GEFDETRFHAGASTMPLSFGVTPYGYAS 401
             + +Y  +  N  G  +   SV+VK        G+   +R      T+  S      G   
Sbjct: 22743 SGKYTLTVKNASG--TKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGG--- 22797

Query: 402   RFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS 461
                                            EI H+  E +        S   WV  +  
Sbjct: 22798 ------------------------------AEITHYIVERR------ETSRLNWV--IVE 22819

Query: 462   GERATLTF--SHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVK 517
             GE  TL++  + L K +E ++ +R   + G      S  +  R++   I   P  P +V 
Sbjct: 22820 GECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNS-FTIPSPPGIPEEV- 22877

Query: 518   CLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCN-DTPVKFARFPVTGLIE 576
                  K++III W +P  DGG+ I  Y +DK E  +  W++ N D  V   R  VT L+E
Sbjct: 22878 --GTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 22935

Query: 577   GRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGI 636
             G  Y FRV AVN  G   PS  S  ++  +P+                            
Sbjct: 22936 GCDYQFRVTAVNAAGNSEPSEASNFISCREPS---------------------------Y 22968

Query: 637   VPGPPTDLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSP 695
              PGPP+   V + T+  + L+W KP    G + + Y +E  E  T+ W RV+T   +++ 
Sbjct: 22969 TPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 23028

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
              F + DL  G+ Y FRV   N  G+ E SE+       ++++IP                
Sbjct: 23029 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP---------------- 23072

Query: 756   VVSWEESKDAKELV----GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLV-TGQSY-IF 809
                 E + D K+ V    G  +   V+ SG+  P      +G       ++ T +SY + 
Sbjct: 23073 --DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLL 23130

Query: 810   RVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGR--VHEASPP 867
              V  VN     +Y+ ++E         G  S  V   + D PG   + + +    ++   
Sbjct: 23131 IVDKVNRYDAGKYTIEAE------NQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTI 23184

Query: 868   TFQKDALLGSKPNKPSL---PSSSQNLGQTEVSKVSETVQE-----ELTPPPQKAAPQGK 919
             T++   + G  P    +     ++    +T  +K S+T+       E T    +  P+  
Sbjct: 23185 TWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENI 23244

Query: 920   SKSDPLKKKTDRA----PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREV 975
                    + +D       P  P  +  ++  + ++ L W++P   GG+ +TGY +   E 
Sbjct: 23245 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVL---EA 23301

Query: 976   IDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWT 1035
                   +W +      +   + +++L E   Y F++ A N  G+  P         ++  
Sbjct: 23302 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23361

Query: 1036  I-----AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGL 1090
             +         P  ++     R   LV+    P+     P   +F     +K +E + R  
Sbjct: 23362 VLPTIDLSTMPQKTIHVPAGRPVELVI----PIAGRPPPAASWF--FAGSKLRESE-RVT 23414

Query: 1091  NEAAIKNVYLKVR--GLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNV 1148
              E   K   L +R   +++   Y   ++ +     G  S+    ++ + +PG     + +
Sbjct: 23415 VETHTKVAKLTIRETTIRDTGEYTLELKNV----TGTTSETIKVIILD-KPGPPTGPIKI 23469

Query: 1149  DDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPR---LEVESKGNKTKMTFKDLGMDDL 1205
             D+    S+    +          S   V   D+ R   L V     ++   F  L   + 
Sbjct: 23470 DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNE 23529

Query: 1206  GIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQ 1265
              ++    T+  GI  SYL  E     ++      + P  P   ++  ++   G    W  
Sbjct: 23530 YVFRVAATNRFGI-GSYLQSE-----VIECRSSIRIPGPPETLQI-FDVSRDGMTLTWYP 23582

Query: 1266  AEKLSGNAKVNYIFNEKEI 1284
              E   G+    YI   KE+
Sbjct: 23583 PEDDGGSQVTGYIVERKEV 23601



 Score =  131 bits (329), Expect = 6e-30
 Identities = 97/326 (29%), Positives = 140/326 (42%), Gaps = 46/326 (14%)

Query: 418  EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDE 477
            EGE +S+       P      P + W+++G  +  S  +        A L      + D 
Sbjct: 8028 EGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8082

Query: 478  GLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAV 535
            G+YTI +  ++G               + ++ G P    D+K  +  K    ++W+ P  
Sbjct: 8083 GIYTITLENKLGSA---------TASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 8133

Query: 536  DGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFP 595
            DGG+PIL Y +++ E G  ++        K + + V  LI    Y FRV+AVNK+G G  
Sbjct: 8134 DGGTPILHYVLERREAGRRTYIPVMSGENKLS-WTVKDLIPNGEYFFRVKAVNKVGGGEY 8192

Query: 596  SRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVV 655
              +  PV A DP +                            P PP D+ V   T   + 
Sbjct: 8193 IELKNPVIAQDPKQP---------------------------PDPPVDVEVHNPTAEAMT 8225

Query: 656  LSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRC 714
            ++WKPP   G   IM Y +EK   G E W+R N  L V    +    L EGK Y FRVR 
Sbjct: 8226 ITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRA 8284

Query: 715  SNSAGVGEPSEATEVTVVGDKLDIPK 740
             N+AG+ EPS AT  T   D +D PK
Sbjct: 8285 ENAAGISEPSRATPPTKAVDPIDAPK 8310



 Score =  129 bits (323), Expect = 3e-29
 Identities = 129/471 (27%), Positives = 187/471 (39%), Gaps = 95/471 (20%)

Query: 288   VWEKENVKLHCSIAGWPEPRVTWYK-------NQVPINVHANPGKYIIESRYGMHTLEIN 340
             V E  NV +   I G P P +TW+K       N+ P+    +  K +++      TL I 
Sbjct: 9756  VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTC---TLVIP 9812

Query: 341   GCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYA 400
                  DT  Y  +A+N  G  S               E R +      P      P G  
Sbjct: 9813  QSRRSDTGLYTITAVNNLGTAS--------------KEMRLNVLGRPGP------PVG-P 9851

Query: 401   SRFEIHFDDKFDVS-FGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTL 459
              +FE    D+  +S F  + +  S     VI                    +   WV   
Sbjct: 9852  IKFESVSADQMTLSWFPPKDDGGSKITNYVIEKR---------------EANRKTWVHVS 9896

Query: 460   WSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGA------PAAP 513
                +  T T   L +  E ++ I  +        + Y      D+E E A      P AP
Sbjct: 9897  SEPKECTYTIPKLLEGHEYVFRIMAQ--------NKYGIGEPLDSEPETARNLFSVPGAP 9948

Query: 514   LDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKF----ARF 569
                      ++ + ++W++P  DGGSP+ GY+++  +  +  W + N  P+K       +
Sbjct: 9949  DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSY 10008

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGLIEG  Y FRV A+N  G+G  S  S+P  A DP           AP         
Sbjct: 10009 KVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPI----------AP--------- 10049

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT 688
                     PGPP    VT+ T+S   L W PP + G   +  Y VE  E G E W++   
Sbjct: 10050 --------PGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEK-GK 10099

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 739
             +  V+  +  +  L EG  Y FRVR  N AG+GEP E T+V  + D+L  P
Sbjct: 10100 DKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP 10150



 Score =  125 bits (313), Expect = 5e-28
 Identities = 183/774 (23%), Positives = 298/774 (38%), Gaps = 129/774 (16%)

Query: 274   LHAPEFIIKP---RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIES 330
             L APE  I     ++H V    +++L  +  G P P   W K    +++ A+     I +
Sbjct: 21980 LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD-----IHT 22034

Query: 331   RYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
                  TL +  C+  D  +Y  +  N  G  S   +V V    G              P+
Sbjct: 22035 TDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-----------PGPI 22083

Query: 391   SFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPL 450
             +F     G A+                +   +  G R      I H+  E +        
Sbjct: 22084 TFKDVTRGSATLMW-------------DAPLLDGGAR------IHHYVVEKR------EA 22118

Query: 451   SPSKWVQTLWSGERATLTFSHLNKEDEGL-YTIRVRMGEYYEQYSAYVFVRDADAEIEGA 509
             S   W Q +   E+ T     +N   EG+ Y  RV     Y     Y       A  + A
Sbjct: 22119 SRRSW-QVI--SEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPA 22175

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P   LDV  ++ +K   +++W +P  DGGS I GY ++  + G+D W +   T  K   F
Sbjct: 22176 PPRRLDV--VDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT--KQLTF 22231

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTG---QII 626
              V  L+E   Y FRV+A N  G   P      V   +P      +  P+A  TG   Q+I
Sbjct: 22232 TVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEP------QIEPTADLTGITNQLI 22285

Query: 627   VTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRV 686
               +         G P  + V  + R    ++WK    R        +++ +  +    + 
Sbjct: 22286 TCK--------AGSPFTIDVPISGRPAPKVTWKLEEMR--------LKETDRVSITTTKD 22329

Query: 687   NTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKII 746
              T L VK       D   G S  + +   N+AGV   + +  V V+G    +    G I 
Sbjct: 22330 RTTLTVK-------DSMRGDSGRYFLTLENTAGV--KTFSVTVVVIGRPGPV---TGPIE 22377

Query: 747   PSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTG 804
              S  +  S V+SW E KD    E+  Y +E   +G+  W+  N++ VK ++     L   
Sbjct: 22378 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKY 22436

Query: 805   QSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV--- 861
               Y FRV + N  G+S+  + +  I           P V P+    P     S   +   
Sbjct: 22437 MEYSFRVSSENRFGVSKPLESAPII--------AEHPFVPPSAPTRPEVYHVSANAMSIR 22488

Query: 862   -----HEASPPTF-------QKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTP 909
                  H+             +++ +L  K NK  +P    N    +V+ + E ++ +   
Sbjct: 22489 WEEPYHDGGSKIIGYWVEKKERNTILWVKENK--VPCLECNY---KVTGLVEGLEYQFRT 22543

Query: 910   PPQKAAPQGKSK--SDPLKKKTDRAPPSPP--CDITCLESFRDSMVLGWKQPDKIGGAEI 965
                 AA   K+   S P+  +     P  P   D+T     R ++ L W  P   GG+++
Sbjct: 22544 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVT-----RSTVSLIWSAPAYDGGSKV 22598

Query: 966   TGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GY +  + V +   G+W + N   VS+  + ++ L E   Y+F+V A N AG+
Sbjct: 22599 VGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGV 22652



 Score =  122 bits (307), Expect = 2e-27
 Identities = 234/997 (23%), Positives = 368/997 (36%), Gaps = 139/997 (13%)

Query: 508  GAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFA 567
            G P +P  +   E  K  I + WK+P  +GGSPI GY I+K       + + N       
Sbjct: 8921 GPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTT 8980

Query: 568  RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALD---PAEKARLKSRPSAPWTGQ 624
             F V  L E + Y FRV+AVN++G   PS     V   D   P  K RL  R        
Sbjct: 8981 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDT----- 9035

Query: 625  IIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQ 684
            I V   EP    +P   T L + +       + W     +    I    +  +   E   
Sbjct: 9036 IKVKAGEPVH--IPADVTGLPMPK-------IEWS----KNETVIEKPTDALQITKEEVS 9082

Query: 685  RVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGK 744
            R   +  +  P+    D        + V  SN  G    +   EV       D P  P  
Sbjct: 9083 RSEAKTELSIPKAVREDKGT-----YTVTASNRLGSVFRNVHVEV------YDRPSPPRN 9131

Query: 745  IIPSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGK--WEPCNNNPVKGSRFTCHG 800
            +  +     S  ++W+   D    E+  Y I+   A   K  WE   N  V+  R+    
Sbjct: 9132 LAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVE-KRYGIWK 9190

Query: 801  LVTGQSYIFRVRAVNAAGLSEYSQDSEAI--------------EVKAAIGGGVSPDVCPA 846
            L+    Y FRVRAVN  G+S+  +  + +              +V A   G +     P 
Sbjct: 9191 LIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPP 9250

Query: 847  LSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEE 906
            L +    +T       E   P +       S+ ++  +        +  V ++ E V+ +
Sbjct: 9251 LDNGGSPITGYWLEKREEGSPYW-------SRVSRAPITKVGLKGVEFNVPRLLEGVKYQ 9303

Query: 907  LTPPPQKAAPQG--KSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
                   AA  G     SDP        PP PP      +  + S+ LGWK P K GG+ 
Sbjct: 9304 FRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSP 9363

Query: 965  ITGYYVNYREVIDGVPGKWREANV--KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
            I GY V  +E  +G    W+  N   K ++     + NLKE   Y+F+V A+N AG   P
Sbjct: 9364 IKGYIVEMQE--EGTTD-WKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEP 9420

Query: 1023 SAVSECFKC----EEWTIAVP-GPPHSLKCSEVRKDSLVLQWKPPVHSGR-TPVTGYFVD 1076
            S  +         EE  + +  G    L C    +  +     P V  GR TP + +  D
Sbjct: 9421 SDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRI-----PAVIKGRPTPKSSWEFD 9475

Query: 1077 LKEAKAKEDQWRGLNE-----AAIKNVYLKVRGLKEGVSYVFRVRAINQAGVG------K 1125
             K  KA +D    + E      A  +  + +   K   +  + + A N+AG        K
Sbjct: 9476 GKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVK 9535

Query: 1126 PSDLAGP-----VVAETRPGTKEVVVNVDDDGVISLN-FECDKMTPKSEFSWSKDYVSTE 1179
              D+ GP     V   TR   +      DDDG   +  +  +K T   + +W+K      
Sbjct: 9536 VMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGK-AWTK------ 9588

Query: 1180 DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEH 1239
                  V      T     DL  +    +     +  GI        E ++R  A    +
Sbjct: 9589 ------VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPV----ETIQRTTARDPIY 9638

Query: 1240 KFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFE--GPKYKMHIDRN 1297
              P  P+K  L + ++ K  V    +  K  G + V +   E   ++  G K +     N
Sbjct: 9639 P-PDPPIK--LKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN 9695

Query: 1298 TGIIEMFMEKLQDEDEG-TYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQ 1356
               +E     ++D  EG  Y F++   KA N + V          +  A     +  R  
Sbjct: 9696 KRDVEELQFTVEDLVEGGEYEFRV---KAVNAAGVS---------KPSATVGPCDCQRPD 9743

Query: 1357 GPHFVEYLSW-EVTGECNVLLKCKVANIKKETHIVWYK------DEREISVDEKHDFK-- 1407
             P  ++   + EV    NV +  K+  +   T + W+K      D +E  + + H  K  
Sbjct: 9744 MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPT-LTWFKAPPKKPDNKEPVLYDTHVNKLV 9802

Query: 1408 -DGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
             D  CTL+I +  + D G+Y +   ++ G     ++L
Sbjct: 9803 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9839



 Score =  121 bits (304), Expect = 5e-27
 Identities = 115/467 (24%), Positives = 177/467 (37%), Gaps = 86/467 (18%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             TV   + ++L   + G P P V W K++   ++  +P +  I++R       +      D
Sbjct: 11840 TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSD 11898

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
               +Y  +A N  G   AYA+V V    G     +                          
Sbjct: 11899 GGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKI------------------------- 11933

Query: 407   FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                  DVS  R        C V   P       EIQ Y     L   +  + +WS   AT
Sbjct: 11934 ----VDVSSDR--------CTVCWDPPEDDGGCEIQNY----ILEKCETKRMVWSTYSAT 11977

Query: 467   L-----TFSHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCL 519
             +     T + L + +E ++ +R   ++G      S  V  +         P  P   +  
Sbjct: 11978 VLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTK----YDKPGRPDPPEVT 12033

Query: 520   EANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRS 579
             + +K+ + + W  P  DGG  I GYF++K E  +  W   N + +   R  V  L+    
Sbjct: 12034 KVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHE 12093

Query: 580   YIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPG 639
             Y FRV+A N++GIG PS  S PV A DP E                            PG
Sbjct: 12094 YQFRVKAENEIGIGEPSLPSRPVVAKDPIEP---------------------------PG 12126

Query: 640   PPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCE------AGTENWQRVNTELPVK 693
             PPT+  V + T+  + L W  P   G   I+ +V +        +  E W+R N    + 
Sbjct: 12127 PPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLV 12186

Query: 694   SPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
                F +  L E + Y FRV   N  G+G P+E  E     + L+ P+
Sbjct: 12187 RKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPE 12233



 Score =  120 bits (300), Expect = 1e-26
 Identities = 118/471 (25%), Positives = 184/471 (39%), Gaps = 81/471 (17%)

Query: 277   PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
             P   +   ++++   E++K+   + G P P ++W K+  P+       +  +E       
Sbjct: 17940 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLK---QTTRVNVEETATSTV 17996

Query: 337   LEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTP 396
             L I   + +D  +Y  +A N  G  +   SV+V    G                     P
Sbjct: 17997 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--------------------PP 18036

Query: 397   YGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWV 456
              G     E+  D    V    E    + GC++      K       W+     ++     
Sbjct: 18037 VGPVRFDEVSAD---FVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVA----- 18088

Query: 457   QTLWSGERATLTFSHLNKEDEGLYTIRV----RMGEYYEQYSAYVFVRDADAEIEGAPAA 512
                    R T+  + L    E  Y  R+    R G+     S  V V+    E  G P  
Sbjct: 18089 -------RTTIKITKLKTGTE--YQFRIFAENRYGKSAPLDSKAVIVQYPFKE-PGPPGT 18138

Query: 513   PLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVT 572
             P        +KD +++ W +P  DGG+ I+GY +++ E  +  W + N TP++  +F  T
Sbjct: 18139 PF---VTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTT 18195

Query: 573   GLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEP 632
             GL EG  Y F+V A N +GIG PS+VSE   A DP +                       
Sbjct: 18196 GLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDP---------------------- 18233

Query: 633   SEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELP 691
                  PG P  + +   TR+ V L WK P   G   I  Y VEK +     W + +    
Sbjct: 18234 -----PGRPEAIVI---TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASF-TN 18284

Query: 692   VKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKA 741
             V    F +  L E + Y FRV   N+AG   EPS+++      D++D P A
Sbjct: 18285 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNA 18335



 Score =  117 bits (293), Expect = 9e-26
 Identities = 95/316 (30%), Positives = 144/316 (45%), Gaps = 39/316 (12%)

Query: 510  PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
            P+ PLD+   +A + +I I+WK P  +GGSPI+GY ++ C VGT+ W + N  P+K  +F
Sbjct: 7913 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 7972

Query: 570  PV-TGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVT 628
             V  G++  + Y+ RVRAVN +G+  PS +SE V A DP  K  +        T  IIV 
Sbjct: 7973 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLE-----THDIIVI 8027

Query: 629  EEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNT 688
            E E     +P P   + V         +SW   G+         V+  +  T     ++ 
Sbjct: 8028 EGEKLS--IPVPFRAVPVP-------TVSWHKDGKE--------VKASDRLTMKNDHISA 8070

Query: 689  ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPS 748
             L V  P+    D        + +   N   +G  + +  V V+G    +P     I  S
Sbjct: 8071 HLEV--PKSVRADAG-----IYTITLENK--LGSATASINVKVIG----LPGPCKDIKAS 8117

Query: 749  RNTDTSVVVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQS 806
              T +S  ++WE  E      ++ Y +E   AG   + P  +   K S +T   L+    
Sbjct: 8118 DITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLS-WTVKDLIPNGE 8176

Query: 807  YIFRVRAVNAAGLSEY 822
            Y FRV+AVN  G  EY
Sbjct: 8177 YFFRVKAVNKVGGGEY 8192



 Score =  117 bits (292), Expect = 1e-25
 Identities = 89/308 (28%), Positives = 141/308 (45%), Gaps = 18/308 (5%)

Query: 922   SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPG 981
             SDP+  +     P  P          +S+ L W +P+  GG+EI  Y +  RE       
Sbjct: 21768 SDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKST--- 21824

Query: 982   KW-REANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
             +W +  + + +SE  +K++ L E   Y+F V A N AG+G  S +S   KC E  +  PG
Sbjct: 21825 RWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCRE-PVNPPG 21883

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVY 1099
             PP  +K ++  K ++ L+W  PV  G   + GY +++   KA    W  +N EA +K  Y
Sbjct: 21884 PPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEM--CKADLGDWHKVNAEACVKTRY 21941

Query: 1100  LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVV-------NVDDDG 1152
               V  L+ G  Y FRV AIN AG G   ++ G + A  R    E+ +       +V   G
Sbjct: 21942 -TVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAG 22000

Query: 1153  VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
                  F   +  P     WSK    +  S R ++ +  + + +T ++   +D G Y+  V
Sbjct: 22001 ASIRLFIAYQGRPTPTAVWSKP--DSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV 22058

Query: 1213  TDTDGIAS 1220
              +  G  S
Sbjct: 22059 ENNSGSKS 22066



 Score =  116 bits (290), Expect = 2e-25
 Identities = 133/548 (24%), Positives = 220/548 (40%), Gaps = 61/548 (11%)

Query: 638   PGPPTD-LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             PGPP   +   E +  +VV+SW+PP   G   I  Y VEK +  T  W  V+    V   
Sbjct: 18033 PGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSAT--VART 18090

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
                +  L  G  Y FR+   N  G   P ++  V +V      P  PG    +  +   +
Sbjct: 18091 TIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAV-IVQYPFKEPGPPGTPFVTSISKDQM 18149

Query: 756   VVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRA 813
             +V W E  +    +++GY++E     S  W   N  P++ ++F   GL  G  Y F+V A
Sbjct: 18150 LVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA 18209

Query: 814   VNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG-----LTASRGRVHEASPPT 868
              N  G+ + S+ SE           V+ D C    D PG      +T +   +    P  
Sbjct: 18210 ENIVGIGKPSKVSECF---------VARDPC----DPPGRPEAIVITRNNVTLKWKKPAY 18256

Query: 869   FQKDALLGSKPNKPSLP------SSSQNLGQTE--VSKVSETVQEELTPPPQKAAPQGKS 920
                  + G    K  LP      +S  N+ +TE  VS + E  + E     + AA     
Sbjct: 18257 DGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSE 18316

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
              SD     T R     P + +    ++D +V+        G   +    +  + + D V 
Sbjct: 18317 PSDSSGAITARDEIDAP-NASLDPKYKDVIVV------HAGETFVLEADIRGKPIPDVVW 18369

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAA------MNMAGLGAPSAVSECFKCEEW 1034
              K  +   +  +    K +  K  +V +  +        + ++ +G   ++    K    
Sbjct: 18370 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVK---- 18425

Query: 1035  TIAVPGPPHS-LKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
              +  PGPP   LK + V  +   L W PP+  G   ++ Y ++ +E       W  ++  
Sbjct: 18426 VLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS--WTQVS-T 18482

Query: 1094  AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA------ETRPGTKEVVVN 1147
              ++ +  KV  L  G  Y+FRV A+N+ G+G+P + +GPV A         P T EV   
Sbjct: 18483 EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE-SGPVTACNPYKPPGPPSTPEVSAI 18541

Query: 1148  VDDDGVIS 1155
               D  V++
Sbjct: 18542 TKDSMVVT 18549



 Score =  115 bits (289), Expect = 3e-25
 Identities = 166/757 (21%), Positives = 275/757 (36%), Gaps = 129/757 (17%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             E +K++  IAG P P ++W K+ + I   A   +  I S      L +  C   DT QY 
Sbjct: 19433 EVLKINADIAGRPLPVISWAKDGIEIEERA---RTEIISTDNHTLLTVKDCIRRDTGQYV 19489

Query: 352   ASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF-GVTPYGYASRFEIHFDDK 410
              +  NV G  S   +  V       D+    AG    PL   G+T             +K
Sbjct: 19490 LTLKNVAGTRSVAVNCKV------LDKPGPPAG----PLEINGLTA------------EK 19527

Query: 411   FDVSFGREGET--MSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGE--RAT 466
               +S+GR  E     +   +V   E  H    + W              T+  GE    +
Sbjct: 19528 CSLSWGRPQEDGGADIDYYIVEKRETSH----LAW--------------TICEGELQMTS 19569

Query: 467   LTFSHLNKEDEGLYTI----RVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEAN 522
                + L K +E ++ +    +  +GE  E     V ++  D      P+ P  ++     
Sbjct: 19570 CKVTKLLKGNEYIFRVTGVNKYGVGEPLES----VAIKALDPFT--VPSPPTSLEITSVT 19623

Query: 523   KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIF 582
             K+ + + W +P  DGGS I GY I++ E  +  W + N  PV   R   TGL EG  Y +
Sbjct: 19624 KESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEY 19683

Query: 583   RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
             RV A N  G+  PS  S  + A DP                             +P PP+
Sbjct: 19684 RVYAENAAGLSLPSETSPLIRAEDPV---------------------------FLPSPPS 19716

Query: 643   DLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFD 701
                + ++ ++ + ++W KP    G     Y VE  ++   +W+     L  +   + +  
Sbjct: 19717 KPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL--RGTEYTISG 19774

Query: 702   LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK-------LDIPKAPGKIIPSRNTDTS 754
             L  G  Y FRV+  N  G  +PS++++  +  ++       +D       I+ +  + T 
Sbjct: 19775 LTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTM 19834

Query: 755   VV---------VSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQ 805
              V         V W +         Y        S   E  N N       T   +++  
Sbjct: 19835 TVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 19894

Query: 806   SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEAS 865
             S    V+ ++  G        +  +  A +   V         +  GG       + +  
Sbjct: 19895 SLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV--------PENDGGAPVKNYHIEKRE 19946

Query: 866   PPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPL 925
                  K A +    N   L     NL +  +     + + E          +G       
Sbjct: 19947 A---SKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEG------- 19996

Query: 926   KKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWRE 985
              K T++  P     +T +   +DS+ L W +P+  GG+ I  Y V   E ++     W +
Sbjct: 19997 VKITEKPSPPEKLGVTSIS--KDSVSLTWLKPEHDGGSRIVHYVV---EALEKGQKNWVK 20051

Query: 986   ANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
               V       + +S L+EN  Y F+V A N AGL  P
Sbjct: 20052 CAV--AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 20086



 Score =  113 bits (282), Expect = 2e-24
 Identities = 82/300 (27%), Positives = 136/300 (45%), Gaps = 26/300 (8%)

Query: 934   PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
             P PP          D M L W  P   GG+E+TG++V  +E    +   W++ N   +S 
Sbjct: 21385 PGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSIL---WQKVNTSPISG 21441

Query: 994   EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVP--GPPHSLKCSEVR 1051
               Y+ + L E + YQF+V A N AGL +PS  S+      +T+AV    PP +    +V 
Sbjct: 21442 REYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK------FTLAVSPVDPPGTPDYIDVT 21495

Query: 1052  KDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSY 1111
             ++++ L+W PP+  G + + GY ++ ++     ++W   N   +      V GL  G  Y
Sbjct: 21496 RETITLKWNPPLRDGGSKIVGYSIEKRQGN---ERWVRCNFTDVSECQYTVTGLSPGDRY 21552

Query: 1112  VFRVRAINQAG-VGKPSDLAGPVVAETRPGTKEVVVNVDD---DGVISLNFECDKMT--- 1164
              FR+ A N  G +  PS  +G ++  TR      +V       DG+I  + E  ++    
Sbjct: 21553 EFRIIARNAVGTISPPSQSSGIIM--TRDENVPPIVEFGPEYFDGLIIKSGESLRIKALV 21610

Query: 1165  ---PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
                P    +W KD V  E    +E+      T +  +D   D  G+Y+ +  +  G A +
Sbjct: 21611 QGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKA 21670



 Score =  112 bits (279), Expect = 4e-24
 Identities = 71/232 (30%), Positives = 103/232 (44%), Gaps = 28/232 (12%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P  P   +     KD ++++W +P  DGG+ I GY ++K +     W++CN   +   R 
Sbjct: 18530 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRL 18589

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGL EG SY FRV A N  G+G PS  S    A D                       
Sbjct: 18590 RVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDAL--------------------- 18628

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT 688
                     PGPP++  VT+ +RS V L+W  P   G   +  Y VE  EA  + W     
Sbjct: 18629 ------YPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTP 18682

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
                ++  +F +  L E   Y FR+   NS GVGEP+      V  ++++ P+
Sbjct: 18683 PTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18734



 Score =  108 bits (269), Expect = 6e-23
 Identities = 127/511 (24%), Positives = 214/511 (41%), Gaps = 52/511 (10%)

Query: 638   PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
             PGPP  + + E +   + +SW PP   G   I  Y VEK E  +  W  V+  +   S +
Sbjct: 19116 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIK 19175

Query: 697   FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
               +  L  G  Y FRV   N  G    SE++ V V       P  PG       T ++++
Sbjct: 19176 --IVRLTTGSEYQFRVCAENRYGKSSYSESSAV-VAEYPFSPPGPPGTPKVVHATKSTML 19232

Query: 757   VSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             V+W+   +     ++GY++E     S  W   N   +  ++    GL  G  Y +RV A 
Sbjct: 19233 VTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAE 19292

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVC-PALSDEPGGLTASRGRVHEASPPTFQKDA 873
             N AG+ + S+  E +  +         D C P    E   +T     +  + P       
Sbjct: 19293 NIAGIGKCSKSCEPVPAR---------DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAK 19343

Query: 874   LLGSKPNKPSLPS------SSQNLGQT--EVSKVSETVQEELTPPPQKAAPQGKSKSD-- 923
             + G    +  LP       +  N+ +T  EV++++E  + E     + AA      S+  
Sbjct: 19344 ITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSEST 19403

Query: 924   -PLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGY---YVNYREVIDGV 979
              P+  K D  PP    D+     FRD +V+   +  KI  A+I G     +++ +  DG+
Sbjct: 19404 GPIIVKDDVEPPRVMMDV----KFRDVIVVKAGEVLKI-NADIAGRPLPVISWAK--DGI 19456

Query: 980   PGKWREANVKAVSEEAYKISNLKENM---VYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
               + R A  + +S + + +  +K+ +     Q+ +   N+AG       S    C+   +
Sbjct: 19457 EIEER-ARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG-----TRSVAVNCK--VL 19508

Query: 1037  AVPGPPHS-LKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 1095
               PGPP   L+ + +  +   L W  P   G   +  Y V+ +E       W  + E  +
Sbjct: 19509 DKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE--TSHLAWT-ICEGEL 19565

Query: 1096  KNVYLKVRGLKEGVSYVFRVRAINQAGVGKP 1126
             +    KV  L +G  Y+FRV  +N+ GVG+P
Sbjct: 19566 QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 19596



 Score =  107 bits (267), Expect = 1e-22
 Identities = 81/279 (29%), Positives = 125/279 (44%), Gaps = 45/279 (16%)

Query: 462  GERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEA 521
            G ++ L      ++D G Y I         +++A      A  E+   P   LD+K +  
Sbjct: 8784 GTKSELIIKDALRKDHGRYVITAT-NSCGSKFAA------ARVEVFDVPGPVLDLKPVVT 8836

Query: 522  NKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYI 581
            N+   +++W  P  DGGS I G+ I++ +    +W Q  +T  + ++  +TGL+EG+ Y 
Sbjct: 8837 NRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIET--ERSKCDITGLLEGQEYK 8894

Query: 582  FRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPP 641
            FRV A NK G G P  +  P+ A+DP                               GPP
Sbjct: 8895 FRVIAKNKFGCGPPVEIG-PILAVDPL------------------------------GPP 8923

Query: 642  TD---LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRF 697
            T    L+ TE T+S + L WK P   G   I  Y +EK      +++RVN  L   +  F
Sbjct: 8924 TSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSF 8982

Query: 698  ALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
             + +L E + Y FRV+  N  G  EPS    V +  D++
Sbjct: 8983 LVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEV 9021



 Score =  103 bits (256), Expect = 2e-21
 Identities = 71/193 (36%), Positives = 91/193 (47%), Gaps = 7/193 (3%)

Query: 638   PGPPTD-LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             PGPP   L VT  T     L+W PP Q G   I  Y +EK E    +W +V+TE  V++ 
Sbjct: 18430 PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTE--VQAL 18487

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
              + +  L  G  Y FRV   N  G+GEP E+  VT   +    P  P     S  T  S+
Sbjct: 18488 NYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTAC-NPYKPPGPPSTPEVSAITKDSM 18546

Query: 756   VVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRA 813
             VV+W    D    E+ GY +E       +W  CN   +   R    GL  G SY FRV A
Sbjct: 18547 VVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAA 18606

Query: 814   VNAAGLSEYSQDS 826
              NAAG+ E S+ S
Sbjct: 18607 ENAAGVGEPSEPS 18619



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 161/728 (22%), Positives = 271/728 (37%), Gaps = 135/728 (18%)

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             VF R  DA     P  P + K  + ++  + ++W +P  DGG+P+ GY ++  E   D W
Sbjct: 18620 VFYRACDALYP--PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW 18677

Query: 557   SQCND-TPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKS 615
             + C   T ++  +F VT L E   Y FR+ A+N  G+G P+ +   V A +  E   ++ 
Sbjct: 18678 TTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIEL 18737

Query: 616   RPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQ---RGHEGIMYF 672
                     +++V                L  +   R +V +  +P  +      EGI+  
Sbjct: 18738 DAD---LRKVVV----------------LRASATLRLFVTIKGRPEPEVKWEKAEGIL-- 18776

Query: 673   VEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV 732
                         R   E+        + ++    S  + +   N++G    S+   V V 
Sbjct: 18777 ----------TDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSG----SKTAFVNV- 18821

Query: 733   GDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCNNNP 790
                LD P AP  +        SV +SWE        ++  Y +E        +    NN 
Sbjct: 18822 -RVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNC 18880

Query: 791   VKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDE 850
              K + F    L  G SY FRV A N  G+   ++ +E ++V             P L   
Sbjct: 18881 TK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSE-----------PPL--P 18926

Query: 851   PGGLTASRGRVHEASPPTFQKDALLGSKPN----KPSLPSSSQNLGQTEVSKVSETVQEE 906
             PG +T      + A+    + ++  GSK      +     S +    T+V  +  T+   
Sbjct: 18927 PGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATI-SG 18985

Query: 907   LTPPPQ----KAAPQGKSKSDP-----------LKKKTDRAPPSPPCDITCLESF----- 946
             LT   +     AA   K +SDP           ++ K     P    ++   E       
Sbjct: 18986 LTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVP 19045

Query: 947   ---RDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKE 1003
                R    + W++ D     E T   V+  + +  +  K  EA+ + V      +SN   
Sbjct: 19046 FKGRPQATVNWRK-DGQTLKETTRVNVSSSKTVTSLSIK--EASKEDVGTYELCVSNSAG 19102

Query: 1004  NMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPV 1063
             ++     +  ++  G   P  + E   C+  TI+                     W PP 
Sbjct: 19103 SITVPITIIVLDRPGPPGPIRIDE-VSCDSITIS---------------------WNPPE 19140

Query: 1064  HSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGV 1123
             + G   ++ Y V+ KE  +    W  +++ A+    +K+  L  G  Y FRV A N+ G 
Sbjct: 19141 YDGGCQISNYIVEKKETTS--TTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGK 19197

Query: 1124  GKPSDLAGPVVAE------TRPGTKEVV------------VNVDDDGVISLNFECDKMTP 1165
                S+ +  VVAE        PGT +VV            V V+D G   + +  +    
Sbjct: 19198 SSYSE-SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLE-YKE 19255

Query: 1166  KSEFSWSK 1173
             +S   WSK
Sbjct: 19256 RSSILWSK 19263



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 84/340 (24%), Positives = 135/340 (39%), Gaps = 45/340 (13%)

Query: 274   LHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYII-ESRY 332
             + AP F  + R+  V  + N  L C + G P+P V WY+    I   A+  KY I E + 
Sbjct: 24553 IQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII--ADGLKYRIQEFKG 24610

Query: 333   GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF 392
             G H L I     +D   Y+  A N  G +S  AS+ V+         + H   +   +  
Sbjct: 24611 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEV------PAKIHLPKTLEGMGA 24664

Query: 393   GVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSP 452
                  G     +I F  K D                          P I W +    +  
Sbjct: 24665 VHALRGEVVSIKIPFSGKPD--------------------------PVITWQKGQDLIDN 24698

Query: 453   SKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPA 511
             +   Q + +    +L F + + ++D G Y +  +     +Q       +  + ++   P 
Sbjct: 24699 NGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQ-------KTVELDVADVPD 24751

Query: 512   APLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPV 571
              P  VK  + ++D + ++W +PA DGGS I  Y ++KC    + W +      +  R+ V
Sbjct: 24752 PPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ--ARETRYTV 24809

Query: 572   TGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKA 611
               L    SY FRV A NK G+  PS  SEP    +   +A
Sbjct: 24810 INLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRA 24849



 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 58/224 (25%), Positives = 109/224 (48%), Gaps = 17/224 (7%)

Query: 157   ERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTA 216
             E +K++AA   +++++  E  IT + Q++   +T A  ++ +++ S    Q    + + A
Sbjct: 26634 EEVKKSAATSLEKSIVHEE--ITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIA 26691

Query: 217   SRQSVV----SKQATSALQQEETSEKKSRKVVIREKAER-----LSLRKTLEETET--YH 265
                 V       + T++ +         + + I++ + R       + KT E      Y 
Sbjct: 26692 GATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYD 26751

Query: 266   AKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGK 325
               L+++ L  AP FI +PRS  + E +NV   C I+G P P + W+KN +PI++ +N   
Sbjct: 26752 LTLSKE-LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVS- 26809

Query: 326   YIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
               I     +++LEI      D+ +Y   A N +G+ SA AS++V
Sbjct: 26810 --ISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 112/520 (21%), Positives = 196/520 (37%), Gaps = 54/520 (10%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            FEC+   P     W KD    + + R++++ +    ++      M D G Y+  V     
Sbjct: 3031 FECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYT--VVAGGN 3088

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQ--VRFWMQAEKLSGNAKV 1275
            ++++ L  E    R+ ++  E             V+++EK +  V F +  + +  +   
Sbjct: 3089 VSTAKLFVEGRDVRIRSIKKE-------------VQVIEKQRAVVEFEVNEDDVDAHWYK 3135

Query: 1276 NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVG 1335
            + I    ++ E  KY   ++R   I  MF+ + +  D G YTF        N S+V L  
Sbjct: 3136 DGIEINFQVQERHKYV--VERR--IHRMFISETRQSDAGEYTFVA----GRNRSSVTLYV 3187

Query: 1336 DVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDE 1395
            +  +  Q   E Q       +   F                 C V + + +  I WYK+E
Sbjct: 3188 NAPEPPQVLQELQPVTVQSGKPARF-----------------CAVISGRPQPKISWYKEE 3230

Query: 1396 REISVDEKHDF-KDGI-CTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1453
            + +S   K  F  DG   TLL+ E   +DA +Y    K+D G   +   L  E  + +  
Sbjct: 3231 QLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSP 3290

Query: 1454 EVCKKIALSA--TDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTG 1511
            +    +   A  T L+   T+EG            DLKV+W      I+ S   +     
Sbjct: 3291 DQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFE 3350

Query: 1512 EQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLK-QAAIAEKN 1570
            +   L+I E  P D+G Y     +       T +LS + + +        +   +++   
Sbjct: 3351 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSF 3410

Query: 1571 RARVLGGLPDVV------TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFE 1624
            +   LG  P  +       +  G+ +     V G P PE+ W  N++ +         FE
Sbjct: 3411 KKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFE 3470

Query: 1625 AGR-TAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
                 A   I    +  +G+Y     N  G  T   T++V
Sbjct: 3471 ESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 104/533 (19%), Positives = 203/533 (38%), Gaps = 97/533 (18%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            F C+  T  ++  W ++  +  DS +  +  K     +  +D  +DD   Y+  +T+  G
Sbjct: 6287 FNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 6346

Query: 1218 ----IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
                 A++ +++EE+L+ +            P+K    +E +EK  V FW +  +L  N 
Sbjct: 6347 ENVKSAANLIVEEEDLRIV-----------EPLKD---IETMEKKSVTFWCKVNRL--NV 6390

Query: 1274 KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1333
             + +  N +E+    +    +D+   ++ +  +     DEG Y       K+     ++ 
Sbjct: 6391 TLKWTKNGEEVPFDNRVSYRVDKYKHMLTI--KDCGFPDEGEYIVTAGQDKSVAELLII- 6447

Query: 1334 VGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECN-VLLKCKVANIKKETHIVWY 1392
                                 +    FVE+L  +   E +  +  C+++  +++ ++ WY
Sbjct: 6448 ---------------------EAPTEFVEHLEDQTVTEFDDAVFSCQLS--REKANVKWY 6484

Query: 1393 KDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKE-- 1450
            ++ REI   +K+ F+             KD  I+ +I+KD R  D+       E  K   
Sbjct: 6485 RNGREIKEGKKYKFE-------------KDGSIHRLIIKDCRLDDECEYACGVEDRKSRA 6531

Query: 1451 --LMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTG 1508
               + E+  +I     D+     A G  +        + ++V W  N   +   D+ +  
Sbjct: 6532 RLFVEEIPVEIIRPPQDIL---EAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMM 6588

Query: 1509 VTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAE 1568
              G+   LQI +  P D+G+Y     D                 EA A+ +      I  
Sbjct: 6589 SEGKIHRLQICDIKPRDQGEYRFIAKD----------------KEARAKLELAAAPKIKT 6632

Query: 1569 KNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRT 1628
             ++  V         +  GK L +       P  E  W K  + L++     +   A +T
Sbjct: 6633 ADQDLV---------VDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK---TIDTTAEQT 6680

Query: 1629 AYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVF-IPEEEARMAALESLKG 1680
            + F I      D G+Y +V++NK+G       + V  +P     +   E+  G
Sbjct: 6681 S-FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6732



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 67/296 (22%), Positives = 117/296 (39%), Gaps = 27/296 (9%)

Query: 1378  CKVANIKKETHIVWYKDEREISVDEKHD--FKDGICTLLITEFSKKDAGIYEVILKDDRG 1435
             CK+ N  + T + WY   R++   EK++  ++DG+  L + + +K D G Y   + +D G
Sbjct: 25217 CKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYG 25276

Query: 1436  KDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHN 1495
             +D S  +L  +  +E+    C++     T  KI+   + ++L      +   L    ++ 
Sbjct: 25277 EDSSYAELFVKGVREVYDYYCRR-----TMKKIKRRTDTMRLLERPPEFTLPLYNKTAYV 25331

Query: 1496  GSAIRYSDRVKTGVTGEQIWLQINE---PTPNDKGKYVMELFDGKTGHQKTVDLSGQAYD 1552
             G  +R+   +         W +  +   P  NDK KY  E    K  +Q T++      D
Sbjct: 25332 GENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDK-KYTFE--SDKGLYQLTINSVTTDDD 25388

Query: 1553  EAYAEFQRLKQAAIAEKNRARVLGGLPDV--------------VTIQEGKALNLTCNVWG 1598
               Y    R K    + K +  V    P                   QEG+++     V G
Sbjct: 25389 AEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 25448

Query: 1599  DPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGS 1654
              PPP + W K+ + L+   +  +  E        I      D+G Y +   N  GS
Sbjct: 25449 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGS 25504



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 102/489 (20%), Positives = 180/489 (36%), Gaps = 79/489 (16%)

Query: 1165 PKSEFSWSKDYVSTEDSPRLE-VESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            P  E  W K+ V  E S R+     + N  ++  +D+  +D         +  G  SS+ 
Sbjct: 2059 PDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHA 2118

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
                + K+L+  + E +      K  +A             + E      KV +  +  E
Sbjct: 2119 FLLVQAKQLITFTQELQDVVAKEKDTMAT-----------FECETSEPFVKVKWYKDGME 2167

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQK 1343
            + EG KY+MH DR    + +      D ++ +    ++D      + +++ G V + +++
Sbjct: 2168 VHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVL-VEDENVKTTAKLIVEGAVVEFVKE 2226

Query: 1344 EAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVA--NIKKETHIVWYKDEREISVD 1401
              + +  E                 +GE    L+C V+  NI+ +    WY ++ E+  +
Sbjct: 2227 LQDIEVPE---------------SYSGE----LECIVSPENIEGK----WYHNDVELKSN 2263

Query: 1402 EKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKI 1459
             K+    + G   L + + +K+D G Y  ++  D  K   +LK+       L        
Sbjct: 2264 GKYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTCKLKMKPRPIAILQ------- 2314

Query: 1460 ALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN 1519
                  L  Q   EG  +   V   +E ++  W  +G  ++ SDRV   +  +   L I 
Sbjct: 2315 -----GLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIE 2369

Query: 1520 EPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLP 1579
            + T  D G Y   +          + LS       Y+                 V+  L 
Sbjct: 2370 DMTKEDAGNYSFTI--------PALGLSTSGRVSVYS---------------VDVITPLK 2406

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
            DV  I+  KA+ L C V       V W  N++ +  DD        G      IN    +
Sbjct: 2407 DVNVIEGTKAV-LECKVSVPDVTSVKWYLNDEQIKPDDRVQ-AIVKGTKQRLVINRTHAS 2464

Query: 1640 DSGKYGLVV 1648
            D G Y L+V
Sbjct: 2465 DEGPYKLIV 2473



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 121/559 (21%), Positives = 206/559 (36%), Gaps = 117/559 (20%)

Query: 1168  EFSWSKDYVSTEDSPRLEVESKGNKT-KMTFKDLGMDDLGIYSCDVTDTDGIASSYL--- 1223
             E +W KD    +++   +     + T ++   +L   D G Y C+++   G + + L   
Sbjct: 26376 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26435

Query: 1224  -------------------IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWM 1264
                                 D++  +  +    E K P       + V  L+   V    
Sbjct: 26436 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDS 26495

Query: 1265  QAE---KLSGNAKVNYIFNE--KEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQ 1319
              A+   K +G  +   I+ +  K I +G KYK+  D+    +E+   K    D G YT  
Sbjct: 26496 VAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEI--HKTDTSDSGLYTCT 26553

Query: 1320  LQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCK 1379
             +++   +  S+  L      K  K+ E Q+              +S + T E   +   K
Sbjct: 26554 VKNSAGSVSSSCKLT----IKAIKDTEAQK--------------VSTQKTSE---ITPQK 26592

Query: 1380  VANIKKETHIVWYKDER----EISVDEKHDFKDGICTLLITEFSKKDAG-------IYEV 1428
              A +++E      + E     E    EK   K+    +LI+E  KK A        ++E 
Sbjct: 26593 KAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEE 26652

Query: 1429  ILKDDRGKDKSRLKLVDEAFKELMME------VCKKIALSATDLKIQSTAEGIQLYSFVT 1482
             I K  +  ++ R     +AF   M        V K     ATD+K               
Sbjct: 26653 ITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVK--------------- 26697

Query: 1483  YYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKG--KYVMELFDGKTGH 1540
                      W  NG  +  S+  + GV+G    L I + +  D+G    + +  +G    
Sbjct: 26698 ---------WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKC 26748

Query: 1541  QKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDP 1600
             Q  + LS +  D           A I++          P    I EG+ +  TC + G+P
Sbjct: 26749 QYDLTLSKELSDAP---------AFISQ----------PRSQNINEGQNVLFTCEISGEP 26789

Query: 1601  PPEVSWLKNEKALASDDHCNLKFEAGRTAY-FTINGVSTADSGKYGLVVKNKYGSETSDF 1659
              PE+ W KN   ++     N+     R  Y   I   S +DSGKY +  KN  G  ++  
Sbjct: 26790 SPEIEWFKNNLPISISS--NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 26847

Query: 1660  TVSVF-IPEEEARMAALES 1677
             ++ V  + EE +R   L +
Sbjct: 26848 SLMVLPLVEEPSREVVLRT 26866



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 91/360 (25%), Positives = 148/360 (41%), Gaps = 39/360 (10%)

Query: 175  EEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEE 234
            E  I  S  +T  K+ +A+  S+A K + + K  T     T  R               +
Sbjct: 785  EASIAGSAIATLQKELSAT--SSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTPD 842

Query: 235  TSEKKSRKVVIREKAERLSLRKTLEET-ETYH---AKLNEDHLLHAP-EFIIKP------ 283
            T + ++   V +E    ++     EE  E  H   AK+ E   + AP E  + P      
Sbjct: 843  TYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSG 902

Query: 284  -RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGC 342
             ++ TV E E+V L C I+G+P P VTWY+    I    +   + I  + G+  L I   
Sbjct: 903  LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSID---FQITFQSGIARLMIREA 959

Query: 343  DFEDTAQYRASAMNVKGEL--SAYASVVVKR----------YKGEFDETRFHAGASTMPL 390
              ED+ ++  SA+N  G +  S Y +V V             K   +E RF      +  
Sbjct: 960  FAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMT 1019

Query: 391  SFGVT--PYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGV 448
               +T    G       +F  K  V    EG ++  GC+V   P     +P + W ++GV
Sbjct: 1020 DTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP-----KPHVYWKKSGV 1074

Query: 449  PLSPSKWVQTLWSGE--RATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEI 506
            PL+     +  ++ +     L  S    +D G YTI VR  ++ E  ++   + +AD E+
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVR-NKHGETSASASLLEEADYEL 1133



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 63/303 (20%), Positives = 130/303 (42%), Gaps = 23/303 (7%)

Query: 1039  PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1098
             P  P +L   EV+KDS+ L W+PP+  G   +T Y V+ +E   K   +  +     K  
Sbjct: 18827 PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK--AYATITNNCTKTT 18884

Query: 1099  YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD-DDGVISLN 1157
             + ++  L+EG SY FRV A N+ G+G P++   PV     P     V  VD      ++ 
Sbjct: 18885 F-RIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIK 18943

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             +E  +    S+ +     + T+ S +    ++    + T   L   +  ++     +  G
Sbjct: 18944 WEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKG 19003

Query: 1218  IASSYLIDEEELKRLLALSHEHKFP----TVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
              +    +    + R + +    + P     V  + +L +++  KG+ +           A
Sbjct: 19004 RSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQ-----------A 19052

Query: 1274  KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD--GKATNHSTV 1331
              VN+  + + + E    ++++  +  +  + +++   ED GTY   + +  G  T   T+
Sbjct: 19053 TVNWRKDGQTLKE--TTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITI 19110

Query: 1332  VLV 1334
             +++
Sbjct: 19111 IVL 19113



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 62/233 (26%), Positives = 93/233 (39%), Gaps = 35/233 (15%)

Query: 251   RLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTW 310
             R +++K    T+T         L   PEF +   + T +  ENV+   +I   PEP VTW
Sbjct: 25298 RRTMKKIKRRTDTMRL------LERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTW 25351

Query: 311   YKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
             YK+   I    N  KY  ES  G++ L IN    +D A+Y   A N  GE S  A + V 
Sbjct: 25352 YKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 25411

Query: 371   RYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVI 430
              +    D T         P+                F      +  +EG+++    RV  
Sbjct: 25412 LHPPPTDST-------LRPM----------------FKRLLANAECQEGQSVCFEIRVSG 25448

Query: 431   TPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG-ERATLTFSHLNKEDEGLYTI 482
              P      P ++W ++G PLS    ++ +  G +   L       ED G Y +
Sbjct: 25449 IP-----PPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25496



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 110/549 (20%), Positives = 203/549 (36%), Gaps = 91/549 (16%)

Query: 1132 PVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGN 1191
            P V  T+P   + V    ++G  ++  EC+     ++  W K+      S + E+ + G 
Sbjct: 5911 PPVEFTKPLEDQTV----EEGATAV-LECEVSRENAKVKWFKNGTEILKSKKYEIVADGR 5965

Query: 1192 KTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELA 1251
              K+   D   +D+  Y+CD  D     +  ++                 P V     L 
Sbjct: 5966 VRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVP----------------PHVEFLRPLT 6009

Query: 1252 -VEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQD 1310
             +++ EK   RF  + E    NAKV +  +  EI +G KY   I     +  + + K   
Sbjct: 6010 DLQVREKEMARF--ECELSRENAKVKWFKDGAEIKKGKKY--DIISKGAVRILVINKCLL 6065

Query: 1311 EDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTG 1370
            +DE  Y+ +++  + +   TV         L++EA F +               + EV+ 
Sbjct: 6066 DDEAEYSCEVRTARTSGMLTV---------LEEEAVFTK------------NLANIEVSE 6104

Query: 1371 ECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVIL 1430
               + L C+V+  K    ++WYK + EI    +++        ++TE  K+   I    L
Sbjct: 6105 TDTIKLVCEVS--KPGAEVIWYKGDEEIIETGRYE--------ILTEGRKRILVIQNAHL 6154

Query: 1431 KDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKV 1490
             +D G    RL       K  + E+  +      +L+I    EG +     +   E   V
Sbjct: 6155 -EDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEI---LEGEKAEFVCSISKESFPV 6210

Query: 1491 NWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQA 1550
             W  +   +   D+      G++  L + + T  D G YV+ +   +     TV      
Sbjct: 6211 QWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTV------ 6264

Query: 1551 YDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNE 1610
                                + R++  L D   ++E + +   C V      +  W +NE
Sbjct: 6265 ------------------IEKLRIVVPLKD-TRVKEQQEVVFNCEV-NTEGAKAKWFRNE 6304

Query: 1611 KALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEA 1670
            +A+  D    +  +        I      D   Y + + N  G E      ++ + EE+ 
Sbjct: 6305 EAI-FDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG-ENVKSAANLIVEEEDL 6362

Query: 1671 RMAALESLK 1679
            R+  +E LK
Sbjct: 6363 RI--VEPLK 6369



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 62/235 (26%), Positives = 100/235 (42%), Gaps = 13/235 (5%)

Query: 142   SGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQSTASKQ 201
             S RQ+ V+ IT+ EEE   E + + AQR   +S   +   ++S +       +  +   +
Sbjct: 25863 SRRQREVTEITEIEEEY--EISKH-AQRESSSSASRLLRRRRSLSPTYIELMRPVSELIR 25919

Query: 202   STAS-----KQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRK 256
             S        +  T  R  T  R    S    S+ +     E+ +R  +        +  K
Sbjct: 25920 SRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALK 25979

Query: 257   TLEETETYHAKLNEDH--LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQ 314
             T + +E  +  L++    L HAP   ++ RSH V   +N +   ++   P   V WY N 
Sbjct: 25980 TQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNG 26039

Query: 315   VPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
             V +       K    +  G+ TLEI  C  +D+  YRA   N KGE S YA++ V
Sbjct: 26040 VELQ---ESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 105/531 (19%), Positives = 200/531 (37%), Gaps = 98/531 (18%)

Query: 1147 NVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLG 1206
            N++     + +FEC+         W K+ V  E S + ++  +G   ++   +   +D  
Sbjct: 2844 NIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSA 2903

Query: 1207 IYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQA 1266
             Y+  V   D ++++  +    +  +L   +  +  T+  +    V +  +G    W++ 
Sbjct: 2904 EYTF-VCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFE----VTVNYEGISYKWLK- 2957

Query: 1267 EKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKAT 1326
                         N  EI    K +M   + T  + +    +   D   YTF    GKAT
Sbjct: 2958 -------------NGVEIKSTDKCQMRTKKLTHSLNI--RNVHFGDAADYTFVA--GKAT 3000

Query: 1327 NHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKE 1386
            + +T+ +         +  EF++         H  +    +V  +   + +C+V+  + +
Sbjct: 3001 STATLYVEA-------RHIEFRK---------HIKDI---KVLEKKRAMFECEVS--EPD 3039

Query: 1387 THIVWYKDEREISVDEKHDFKDG--ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLV 1444
              + W KD++E+ + ++   +    +  LLI      DAG Y V+     G + S  KL 
Sbjct: 3040 ITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA----GGNVSTAKLF 3095

Query: 1445 DEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVE------DLKVNWSHNGSA 1498
             E                  D++I+S  + +Q+       VE      D+  +W  +G  
Sbjct: 3096 VEG----------------RDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIE 3139

Query: 1499 IRYS--DRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYA 1556
            I +   +R K  V      + I+E   +D G+Y      G+     T+ ++     +   
Sbjct: 3140 INFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA--GRNRSSVTLYVNAPEPPQVLQ 3197

Query: 1557 EFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD 1616
            E Q                      VT+Q GK       + G P P++SW K E+ L++ 
Sbjct: 3198 ELQP---------------------VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTG 3236

Query: 1617 DHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPE 1667
              C    +        I      D+  Y    KN YG  T+  ++SV +PE
Sbjct: 3237 FKCKFLHDGQEYTLLLIEAF-PEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 46/149 (30%), Positives = 67/149 (44%), Gaps = 9/149 (6%)

Query: 637   VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             VP PP  + V++ +R  V L+W  P   G   I  Y VEKC    E W RV      +  
Sbjct: 24749 VPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ---ARET 24805

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV-GDKLDIPKAPGKIIPSRNTDTS 754
             R+ + +L    SY FRV   N  G+ +PSE +E T+   DK        ++  +R     
Sbjct: 24806 RYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR----E 24861

Query: 755   VVVSWEESKDAKELVGYYIEASVAGSGKW 783
             V ++       KEL   Y+ A   G G++
Sbjct: 24862 VSMTKASHSSTKELYEKYMIAEDLGRGEF 24890



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 101/468 (21%), Positives = 186/468 (39%), Gaps = 77/468 (16%)

Query: 1073 YFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGP 1132
            +F D  E K K  ++  +++ A++ + +    L +   Y   VR    +G+         
Sbjct: 6034 WFKDGAEIK-KGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLT------- 6085

Query: 1133 VVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNK 1192
            V+ E    TK +  N++     ++   C+   P +E  W K      ++ R E+ ++G K
Sbjct: 6086 VLEEEAVFTKNLA-NIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRK 6144

Query: 1193 TKMTFKDLGMDDLGIYSCDVTD--TDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSEL 1250
              +  ++  ++D G Y+C +    TDG    + +  E + +   L               
Sbjct: 6145 RILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL--------------- 6189

Query: 1251 AVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQD 1310
              EILE  +  F     K S    V +  ++K +  G KY +  D    ++ +    LQD
Sbjct: 6190 --EILEGEKAEFVCSISKES--FPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQD 6245

Query: 1311 EDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTG 1370
               GTY   +   +A  H TV+    +   L+     ++QE                   
Sbjct: 6246 M--GTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQE------------------- 6284

Query: 1371 ECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIYEV 1428
               V+  C+V    +     W+++E  I    K+    KD + TL I +    D   Y V
Sbjct: 6285 ---VVFNCEVNT--EGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNV 6339

Query: 1429 ILKDDRGKD-KSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVED 1487
             L + RG++ KS   L+ E     ++E  K I             E ++  S VT++ + 
Sbjct: 6340 SLTNHRGENVKSAANLIVEEEDLRIVEPLKDI-------------ETMEKKS-VTFWCKV 6385

Query: 1488 LKVN----WSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
             ++N    W+ NG  + + +RV   V   +  L I +    D+G+Y++
Sbjct: 6386 NRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIV 6433



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 14/165 (8%)

Query: 1038  VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
             VP PP  +K S+V +DS+ L W  P   G + +T Y V+  +     ++W  + +A  + 
Sbjct: 24749 VPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVE--KCATTAERWLRVGQA--RE 24804

Query: 1098  VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN 1157
                 V  L    SY FRV A N+ G+ KPS+ + P + +     K   +N D++   +  
Sbjct: 24805 TRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE---DKTRAMNYDEEVDETRE 24861

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLE-------VESKGNKTKM 1195
                 K +  S     + Y+  ED  R E       VE+   KT M
Sbjct: 24862 VSMTKASHSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYM 24906



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 36/116 (31%), Positives = 59/116 (50%), Gaps = 7/116 (6%)

Query: 1036 IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE--DQWRGLNEA 1093
            I +PGP   +K S++ K S  L W+PP   G TP+  Y ++ +EA  +       G N+ 
Sbjct: 8105 IGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKL 8164

Query: 1094 AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD 1149
            +       V+ L     Y FRV+A+N+ G G+  +L  PV+A+      +  V+V+
Sbjct: 8165 S-----WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8215



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 96/288 (33%)

Query: 1489  KVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY--VMELFDGKTGHQKTVDL 1546
             +V W HNG  ++ S ++    T   + L+I +   +D G Y  V   + G+     T+D+
Sbjct: 26032 EVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091

Query: 1547  SGQAYD----------------------EAYA--EFQR---------------------- 1560
             +G  Y                       EAYA   F++                      
Sbjct: 26092 TGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRE 26151

Query: 1561  ------------LKQAAIAEKN--------------RARVLGGLPDVVTIQEGKALNLTC 1594
                         +K AA+ EK+               AR+L   P  +T+ EG++   +C
Sbjct: 26152 SLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTK-PRSMTVYEGESARFSC 26210

Query: 1595  NVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAY---FTINGVSTADSGKYGLVVKNK 1651
             +  G+P P V+WL+  + L++    + + +   T Y   F I+ V  +D G Y +VV+N 
Sbjct: 26211 DTDGEPVPTVTWLRKGQVLST----SARHQVTTTKYKSTFEISSVQASDEGNYSVVVENS 26266

Query: 1652  YGSETSDFTVSV--------------FIPEEEARMAALESLKGGKKAK 1685
              G + ++FT+++               +   E R+ + E++K  K+ K
Sbjct: 26267 EGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVK 26314



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 70/284 (24%), Positives = 102/284 (35%), Gaps = 55/284 (19%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P FI    S  V   E V+ H  ++G P+P + W+ NQ  I +      +  E   GM  
Sbjct: 3419 PSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLI-LPTKDVVFHFEESTGMAL 3477

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVV---------------------KRYKGE 375
            + I     E   QY   A N  GE +  A++ V                     K +   
Sbjct: 3478 MLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSS 3537

Query: 376  F---DETRFHAG----------------ASTMPLSFGVTPYGYASRFEIHFDDKFDVSFG 416
            F   +E   H+                 +   P  F     G    F I      D+S  
Sbjct: 3538 FLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIF-IKEVSNADISM- 3595

Query: 417  REGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
              G+  +L   V+  P     +P+IQW+ NGV L+PS   + ++ G+  +L       ED
Sbjct: 3596 --GDVATLSVTVIGIP-----KPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLED 3648

Query: 477  EGLYTIRVRMGEYYEQYSAYVFVRD-----ADAEIEGAPAAPLD 515
            EG YT            SAY+ +        D E E A A  L+
Sbjct: 3649 EGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLE 3692



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 116/592 (19%), Positives = 217/592 (36%), Gaps = 102/592 (17%)

Query: 1165 PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLI 1224
            P+ + SW K+        + +    G +  +   +   +D  +Y+C+  +  G+A++   
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279

Query: 1225 DEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQ-VRFWMQAEKLSGNAKVNYIFNEKE 1283
               E+  +++   E       + + L   +  +GQ  RF  Q      + KV++   +K+
Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARF--QCRVSGTDLKVSWYSKDKK 3337

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQK 1343
            I     ++M    +T  +E+   +   EDEGTYTF   +      ST  L  + F K ++
Sbjct: 3338 IKPSRFFRMTQFEDTYQLEI--AEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEE 3395

Query: 1344 EAEFQRQEW-------IRK----QGPHFVEYLS-WEVTGECNVLLKCKVANIKKETHIVW 1391
                   +W        +K    Q P F++ LS   V     V    +V+ I K   I W
Sbjct: 3396 NTS--NSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKP-EIQW 3452

Query: 1392 YKDEREI--SVDEKHDFKD--GICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLV--- 1444
            + +++ I  + D    F++  G+  +LI +   + AG Y     +  G+      L    
Sbjct: 3453 FHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTP 3512

Query: 1445 --------DEAFKELMMEV---------CKKIALSATDLKIQSTAEGIQLYSFVTYY--- 1484
                    +   +E+ ME+          ++  L + +L++    E ++L S    Y   
Sbjct: 3513 KAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTK 3572

Query: 1485 -----------------------------------VEDLKVNWSHNGSAIRYSDRVKTGV 1509
                                               +   K+ W  NG  +  S   K   
Sbjct: 3573 FDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVF 3632

Query: 1510 TGEQIWLQINEPTPNDKGKYVMELFD--GKT--GHQKTVDLSGQAYDEAYAEFQRLKQAA 1565
             G+   L I      D+G+Y     +  GKT       ++  G+ + +   E      +A
Sbjct: 3633 DGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE------SA 3686

Query: 1566 IAEKNRARVLGG------LPDVVTIQ--EGKALNLTCNVWGDPPPEVSWLKNEKALASDD 1617
            +A+      LGG      L ++  I+  +G        V G+P P V+W K  K L +  
Sbjct: 3687 VAKS--LEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSV 3744

Query: 1618 HCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEE 1669
            +  +      +  F +N     DSG Y    +N  G  T    + V + + +
Sbjct: 3745 YYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTD 3796



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 57/235 (24%), Positives = 100/235 (42%), Gaps = 27/235 (11%)

Query: 1466  LKIQSTAEGIQLYSFVTYYVEDLK-VNWSHNGSAIRYSDRVKTGVTGEQIW-LQINEPTP 1523
             LK +++ E  +L   V   V   K V W  +G  ++ +   +   + +  + L+IN  T 
Sbjct: 26352 LKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 26411

Query: 1524  NDKGKYVMELFDGKTGHQKT-VDLSGQAY----------DEAYAEFQRLKQAAIAEKNRA 1572
             +D+G+YV E+  G+ G  KT +   GQA+           E     Q+  ++ +  K   
Sbjct: 26412 SDQGEYVCEI-SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP 26470

Query: 1573  R----------VLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLK 1622
             +          ++ GL D  T+             G+P P   W K+ KA+       L 
Sbjct: 26471 KAPEPISSKPVIVTGLQD-TTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS 26529

Query: 1623  FEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV-FIPEEEARMAALE 1676
              + G   +  I+   T+DSG Y   VKN  GS +S   +++  I + EA+  + +
Sbjct: 26530 EDKG-GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 26583



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 93/428 (21%), Positives = 159/428 (37%), Gaps = 58/428 (13%)

Query: 1039  PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1098
             PGP   L  S V ++   L W  P   G   +T Y V+ +E       W  +        
Sbjct: 22769 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLN--WVIVEGECPTLS 22826

Query: 1099  YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA--------------ETRPGTKEV 1144
             Y+  R +K    Y+FRVRA+N+ G G P + + P+VA              E   G + +
Sbjct: 22827 YVVTRLIKNN-EYIFRVRAVNKYGPGVPVE-SEPIVARNSFTIPSPPGIPEEVGTGKEHI 22884

Query: 1145  VVN----VDDDGVISLNFECDKMTPKSEFSWS---KDYVSTEDSPRLEVESKGNKTKMTF 1197
             ++       D G    N+  DK   KS   W+   KDYV  +            + K+T 
Sbjct: 22885 IIQWTKPESDGGNEISNYLVDKREKKS-LRWTRVNKDYVVYD-----------TRLKVTS 22932

Query: 1198  KDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEK 1257
                G D    Y   VT  +   +S   +  E    ++   E  +   P  +   V+  + 
Sbjct: 22933 LMEGCD----YQFRVTAVNAAGNS---EPSEASNFISC-REPSYTPGPPSAPRVVDTTKH 22984

Query: 1258  GQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
                  W +     G   V Y+   +E      Y++H +      E  +  L+   +  Y+
Sbjct: 22985 SISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK--YS 23042

Query: 1318  FQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLK 1377
             F++           V V  + +  +  AE +  E I        + L   VT      L+
Sbjct: 23043 FRV---------AAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLR 23093

Query: 1378  CKVANIKKETHIV-WYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGK 1436
               V+   +   ++ W K   +++     D  +    L++ + ++ DAG Y +  ++  GK
Sbjct: 23094 LMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGK 23153

Query: 1437  DKSRLKLV 1444
              KS   LV
Sbjct: 23154 -KSATVLV 23160



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 100/495 (20%), Positives = 186/495 (37%), Gaps = 92/495 (18%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            FEC+     ++  W KD    +   + ++ SKG    +      +DD   YSC+V     
Sbjct: 6021 FECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTART 6080

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
                 +++EE                V  K+   +E+ E   ++   +  K    A+V +
Sbjct: 6081 SGMLTVLEEE---------------AVFTKNLANIEVSETDTIKLVCEVSK--PGAEVIW 6123

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQL----QDGKATNHSTVVL 1333
               ++EI E  +Y++  +    I  + ++    ED G Y  +L     DGK   H     
Sbjct: 6124 YKGDEEIIETGRYEILTEGRKRI--LVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAA- 6180

Query: 1334 VGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYK 1393
                             E+I K  P  +E L  E          C ++  K+   + W +
Sbjct: 6181 -----------------EFISK--PQNLEILEGE-----KAEFVCSIS--KESFPVQWKR 6214

Query: 1394 DEREISVDEKHD-FKDG-ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKEL 1451
            D++ +   +K+D   DG    L++ + + +D G Y V++   R    + L ++++     
Sbjct: 6215 DDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARA--AAHLTVIEKL---- 6268

Query: 1452 MMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTG 1511
                  +I +   D +++   E +      T   E  K  W  N  AI  S +       
Sbjct: 6269 ------RIVVPLKDTRVKEQQEVVFNCEVNT---EGAKAKWFRNEEAIFDSSKYIILQKD 6319

Query: 1512 EQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAA--IAEK 1569
                L+I +   +D+  Y + L    T H+                 + +K AA  I E+
Sbjct: 6320 LVYTLRIRDAHLDDQANYNVSL----TNHRG----------------ENVKSAANLIVEE 6359

Query: 1570 NRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTA 1629
               R++  L D+ T+ E K++   C V       + W KN + +  D+  + + +  +  
Sbjct: 6360 EDLRIVEPLKDIETM-EKKSVTFWCKV-NRLNVTLKWTKNGEEVPFDNRVSYRVDKYK-H 6416

Query: 1630 YFTINGVSTADSGKY 1644
              TI      D G+Y
Sbjct: 6417 MLTIKDCGFPDEGEY 6431



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             +P+ +TI+ GK L +  +V+G P P   W K E  + +  H  +  +A  ++   I  V+
Sbjct: 12532 MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV-HKADSSSILIIKDVT 12590

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG Y L  +N  G++T    V V
Sbjct: 12591 RKDSGYYSLTAENSSGTDTQKIKVVV 12616



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 44/192 (22%), Positives = 83/192 (43%), Gaps = 30/192 (15%)

Query: 180   TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
             T   + +S + T+  ++++S +   S Q T +R+S +S +   S +  SA  +E++ E  
Sbjct: 26119 TEAYAVSSFKKTSEMEASSSVREVKS-QMTETRESLSSYEHSASAEMKSAALEEKSLE-- 26175

Query: 240   SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
                    EK+    ++ TL                 A   + KPRS TV+E E+ +  C 
Sbjct: 26176 -------EKSTTRKIKTTL-----------------AARILTKPRSMTVYEGESARFSCD 26211

Query: 300   IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
               G P P VTW +    ++  A   ++ + +     T EI+     D   Y     N +G
Sbjct: 26212 TDGEPVPTVTWLRKGQVLSTSA---RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEG 26268

Query: 360   ELSAYASVVVKR 371
             +  A  ++ +++
Sbjct: 26269 KQEAEFTLTIQK 26280



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 32/84 (38%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D +TI+ G+A  LT    G P P+VSW K+E  +  DD  ++K      A   I     +
Sbjct: 10454 DKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK-AKRS 10512

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             DSGKY +VV+N  GS      V+V
Sbjct: 10513 DSGKYCVVVENSTGSRKGFCQVNV 10536



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 47/166 (28%), Positives = 72/166 (43%), Gaps = 9/166 (5%)

Query: 1503  DRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQ--- 1559
             +R      G+  WL+ N    +D    V  L +G T   + +  +        +E     
Sbjct: 22604 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22663

Query: 1560  --RLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDD 1617
               R + A    +  AR+ G   D+VTI+ G  L L   V G P P++ W K +K L   +
Sbjct: 22664 TCRDEYAPPKAELDARLHG---DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCE 22720

Query: 1618  HCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               +L++  G+ A   I     +DSGKY L VKN  G++     V V
Sbjct: 22721 KVSLQY-TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV 22765



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 78/375 (20%), Positives = 132/375 (35%), Gaps = 84/375 (22%)

Query: 184  STASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKV 243
            +T +K+    K++         ++S   R     R      +A +A++ +   + +S + 
Sbjct: 1924 TTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEE 1983

Query: 244  VIREKAERLSLRKTLEETETYHAKLNEDHLL----------------HAPEFIIKPRSHT 287
            ++R+  + L L  T E TE     L E+  +                 AP+   + +S T
Sbjct: 1984 LLRKTKDEL-LHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQT 2042

Query: 288  VWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDT 347
            V +  +      + G P+P   WYKN V I        Y  E    +  L I     ED+
Sbjct: 2043 VGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPED--NVCELVIRDVTAEDS 2100

Query: 348  AQYRASAMNVKGELSAYASVVVKRYK-------------GEFDETRFHAGASTMPLSFGV 394
            A     A+N+ GE S++A ++V+  +              E D        ++ P    V
Sbjct: 2101 ASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPF---V 2157

Query: 395  TPYGYASRFEIHFDDKFDVSFGR-----------------------EGETMSLGCRVVIT 431
                Y    E+H  DK+ +   R                       E E +    ++++ 
Sbjct: 2158 KVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVE 2217

Query: 432  PEIKHFQPEIQ------------------------WYRNGVPL-SPSKWVQTLWSGERAT 466
              +  F  E+Q                        WY N V L S  K+  T   G R  
Sbjct: 2218 GAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRG-RQN 2276

Query: 467  LTFSHLNKEDEGLYT 481
            LT   + KED+G Y+
Sbjct: 2277 LTVKDVTKEDQGEYS 2291



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 59/299 (19%), Positives = 114/299 (38%), Gaps = 36/299 (12%)

Query: 1373  NVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDG--ICTLLITEFSKKDAGIYEVIL 1430
             NVL  C+++  +    I W+K+   IS+           + +L I   S  D+G Y +  
Sbjct: 26778 NVLFTCEISG-EPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKA 26836

Query: 1431  KDDRGKDKSR-----LKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYV 1485
             K+ RG+  +      L LV+E  +E+++          T L+   +++ +Q+ +      
Sbjct: 26837 KNFRGQCSATASLMVLPLVEEPSREVVLRTS-----GDTSLQGSFSSQSVQMSAS----- 26886

Query: 1486  EDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVD 1545
                        S   +S    + +T  +      +   + +  +V        G      
Sbjct: 26887 -------KQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQ 26939

Query: 1546  LSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVS 1605
             L             ++ +A I  +     +  LP  ++I EGK L + C   G+P PEV+
Sbjct: 26940 LESST--------SKMLKAGI--RGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVT 26989

Query: 1606  WLKNEKALASDDHCNLKFE-AGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
             W    + + S +      E         I  V   D G Y L + N++GS+++   + +
Sbjct: 26990 WSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 20/157 (12%)

Query: 217  SRQS-VVSKQATSALQQEETSEK---KSRKVVIREKAERLSLRKTLEETETYHAKLNEDH 272
            SR S +++ +AT+    + TS     K  K ++ E+++    RK L+  E      +E  
Sbjct: 1723 SRDSGIITCRATNKYGTDHTSATLIVKDEKSLV-EESQLPEGRKGLQRIEELERMAHEGA 1781

Query: 273  LL---------HAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANP 323
            L            P+ ++ P    V E E  +  C + G+P+P+V WY N   I      
Sbjct: 1782 LTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKR- 1840

Query: 324  GKYIIESRY-GMHTLEINGCDFEDTAQYRASAMNVKG 359
                   RY G+H L+I  C   DT + + +A N +G
Sbjct: 1841 ----FRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEG 1873



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 93/463 (20%), Positives = 166/463 (35%), Gaps = 72/463 (15%)

Query: 1114 RVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSK 1173
            RV A+  +   K + L G        G  +    V+ D VI    +C+     +   W K
Sbjct: 5627 RVEAMGMSSEAKLTVLEGDPYFT---GKLQDYTGVEKDEVI---LQCEISKADAPVKWFK 5680

Query: 1174 DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLL 1233
            D    + S    +++ G K  +  K     D+G Y+CD   TD  +    I++ E+K + 
Sbjct: 5681 DGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD-CGTDKTSGKLDIEDREIKLVR 5739

Query: 1234 ALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMH 1293
             L               +VE++E    RF  + E    +   N+    + + + P     
Sbjct: 5740 PLH--------------SVEVMETETARF--ETEISEDDIHANWKLKGEALLQTP--DCE 5781

Query: 1294 IDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTV-VLVGDVFKKLQKEAEFQRQEW 1352
            I     I  + +   + +  G   FQ  + K++ H  V   V  + + L+          
Sbjct: 5782 IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVT------- 5834

Query: 1353 IRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICT 1412
                           VT        C+++   ++  + WY   +++   +K         
Sbjct: 5835 ---------------VTAGETATFDCELS--YEDIPVEWYLKGKKLEPSDK--------- 5868

Query: 1413 LLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSAT-DLKIQST 1471
                   + +  ++ + L+D + +D   ++L  + FK       K+  +  T  L+ Q+ 
Sbjct: 5869 ----VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTV 5924

Query: 1472 AEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
             EG           E+ KV W  NG+ I  S + +    G    L I++ TP D   Y  
Sbjct: 5925 EEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 5984

Query: 1532 ELFDGKTGHQKTVDLSGQAYDEAYAEFQR-LKQAAIAEKNRAR 1573
            +  D KT     V          + EF R L    + EK  AR
Sbjct: 5985 DAKDFKTSCNLNV-------VPPHVEFLRPLTDLQVREKEMAR 6020



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 96/436 (22%), Positives = 168/436 (38%), Gaps = 62/436 (14%)

Query: 1100 LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFE 1159
            L +R +    S    V+AIN AG             +    T+E+   V  +      FE
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFE 2149

Query: 1160 CDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIA 1219
            C+   P  +  W KD +   +  +  + S      ++   +   D   YSC + + + + 
Sbjct: 2150 CETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVK 2209

Query: 1220 SSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILE--KGQVRFWMQAEKLSGNAKVNY 1277
            ++         +L+      +F    VK    +E+ E   G++   +  E + G     +
Sbjct: 2210 TT--------AKLIVEGAVVEF----VKELQDIEVPESYSGELECIVSPENIEG----KW 2253

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDV 1337
              N+ E+    KY   I    G   + ++ +  ED+G Y+F + DGK T           
Sbjct: 2254 YHNDVELKSNGKYT--ITSRRGRQNLTVKDVTKEDQGEYSFVI-DGKKTT---------- 2300

Query: 1338 FKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVL-LKCKVANIKKETHIVWYKDER 1396
              KL+          ++ +    ++ LS +   E +++ L+ KV+   +    VW KD +
Sbjct: 2301 -CKLK----------MKPRPIAILQGLSDQKVCEGDIVQLEVKVS--LESVEGVWMKDGQ 2347

Query: 1397 EIS-VDEKHDFKDGIC-TLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMME 1454
            E+   D  H   D     LLI + +K+DAG Y   +         R+ +         ++
Sbjct: 2348 EVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-------VD 2400

Query: 1455 VCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDL-KVNWSHNGSAIRYSDRVKTGVTGEQ 1513
            V        T LK  +  EG +        V D+  V W  N   I+  DRV+  V G +
Sbjct: 2401 V-------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTK 2453

Query: 1514 IWLQINEPTPNDKGKY 1529
              L IN    +D+G Y
Sbjct: 2454 QRLVINRTHASDEGPY 2469



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 115/564 (20%), Positives = 203/564 (35%), Gaps = 88/564 (15%)

Query: 1090 LNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD 1149
            L E   + + ++   L++  +Y  R+ +    G  K  +LA   ++  +P   E++    
Sbjct: 6139 LTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFIS--KPQNLEILEGEK 6196

Query: 1150 DDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYS 1209
             + V S++ E   +       W +D  + E   + +V + G K  +  KD  + D+G Y 
Sbjct: 6197 AEFVCSISKESFPV------QWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYV 6250

Query: 1210 CDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKL 1269
              V      A   +I++  +              VP+K      + E+ +V F    E  
Sbjct: 6251 VMVGAARAAAHLTVIEKLRI-------------VVPLKD---TRVKEQQEVVF--NCEVN 6292

Query: 1270 SGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHS 1329
            +  AK  +  NE+ IF+  KY   I +   +  + +     +D+  Y   L + +  N  
Sbjct: 6293 TEGAKAKWFRNEEAIFDSSKYI--ILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVK 6350

Query: 1330 TVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHI 1389
            +   +    + L+     +  E + K+   F     W      NV LK            
Sbjct: 6351 SAANLIVEEEDLRIVEPLKDIETMEKKSVTF-----WCKVNRLNVTLK------------ 6393

Query: 1390 VWYKDEREISVDEKHDFKDGICTLLIT--EFSKKDAGIYEVILKDDRGKDKSRLKLVDEA 1447
             W K+  E+  D +  ++      ++T  +    D G Y V      G+DKS  +L    
Sbjct: 6394 -WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTA----GQDKSVAEL---- 6444

Query: 1448 FKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKT 1507
               L++E   +      D   Q+  E            E   V W  NG  I+   + K 
Sbjct: 6445 ---LIIEAPTEFVEHLED---QTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKF 6498

Query: 1508 GVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIA 1567
               G    L I +   +D+ +Y   + D K+  +  V       +E   E  R  Q  + 
Sbjct: 6499 EKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFV-------EEIPVEIIRPPQDILE 6551

Query: 1568 EKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGR 1627
                        DVV + E   LN           EV WL+N   +   D   +  E G+
Sbjct: 6552 APG--------ADVVFLAE---LN-------KDKVEVQWLRNNMVVVQGDKHQMMSE-GK 6592

Query: 1628 TAYFTINGVSTADSGKYGLVVKNK 1651
                 I  +   D G+Y  + K+K
Sbjct: 6593 IHRLQICDIKPRDQGEYRFIAKDK 6616



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 44/200 (22%), Positives = 83/200 (41%), Gaps = 11/200 (5%)

Query: 1484  YVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKT 1543
             Y +  +V W      +  S++ +         L + + T  D G Y  ++ +        
Sbjct: 25222 YDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSY 25281

Query: 1544  VDLSGQAYDEAYAEFQRLKQAAIAEK-NRARVLGGLPDVV------TIQEGKALNLTCNV 1596
              +L  +   E Y  + R     I  + +  R+L   P+        T   G+ +     +
Sbjct: 25282 AELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTI 25341

Query: 1597  WGDPPPEVSWLKN-EKALASDDHCNLKFEAGRTAY-FTINGVSTADSGKYGLVVKNKYGS 1654
                P P V+W K+ +K    D+     FE+ +  Y  TIN V+T D  +Y +V +NKYG 
Sbjct: 25342 TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE 25401

Query: 1655  ET--SDFTVSVFIPEEEARM 1672
             ++  +  TV++  P  ++ +
Sbjct: 25402 DSCKAKLTVTLHPPPTDSTL 25421



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 49/207 (23%), Positives = 79/207 (38%), Gaps = 35/207 (16%)

Query: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
           AP F    +S  V E         I+G+P P V+W+++   I+    PG  I  S  G  
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSD-GRA 63

Query: 336 TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVT 395
            L I      ++ +Y   A N  G+ ++ A ++VK              A T P      
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK--------------AETAP------ 103

Query: 396 PYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKW 455
                     +F  +      R+G  + L  RV   P      P +++YR+G  +  S  
Sbjct: 104 ---------PNFVQRLQSMTVRQGSQVRLQVRVTGIP-----TPVVKFYRDGAEIQSSLD 149

Query: 456 VQTLWSGERATLTFSHLNKEDEGLYTI 482
            Q    G+  +L  +    ED G Y++
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSV 176



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 2/90 (2%)

Query: 1575  LGGLPDVVTI-QEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTI 1633
             L GLPD+  + +E     L   + G P P VSW K E  LA+D   +++  A  T    +
Sbjct: 13612 LKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTT-LIV 13670

Query: 1634  NGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
                  +D+GKY + +KN  G++    ++ V
Sbjct: 13671 YDCQKSDAGKYTITLKNVAGTKEGTISIKV 13700



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 112/499 (22%), Positives = 178/499 (35%), Gaps = 92/499 (18%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            FEC+       F W K         R E+   G K  M  K    +D   Y  +  D   
Sbjct: 5487 FECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH- 5545

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
             +   +I+   LK L            P+K    V   EK    F    E    N +V +
Sbjct: 5546 TSGKLIIEGIRLKFL-----------TPLKD---VTAKEKESAVF--TVELSHDNIRVKW 5589

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDV 1337
              N++ +       M  +  T  I    + L  +D      +   G ++     VL GD 
Sbjct: 5590 FKNDQRLHTTRSVSMQDEGKTHSIT--FKDLSIDDTSQIRVEAM-GMSSEAKLTVLEGDP 5646

Query: 1338 F--KKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDE 1395
            +   KLQ     ++ E                      V+L+C+++  K +  + W+KD 
Sbjct: 5647 YFTGKLQDYTGVEKDE----------------------VILQCEIS--KADAPVKWFKDG 5682

Query: 1396 REISVDEKHDFK-DGICTLLITEFS-KKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1453
            +EI   +    K DG   +LI + + K D G Y      D G DK+  KL D   +E+  
Sbjct: 5683 KEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKL-DIEDREI-- 5735

Query: 1454 EVCKKIALSATDLKIQSTAEGIQLYSFVTYYVE-DLKVNWSHNGSAIRYSDRVKTGVTGE 1512
                K+      +++  T    +   F T   E D+  NW   G A+             
Sbjct: 5736 ----KLVRPLHSVEVMET----ETARFETEISEDDIHANWKLKGEAL------------- 5774

Query: 1513 QIWLQINEPTPNDKGK-YVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR 1571
               LQ  +    ++GK + + L + +      VD   QA +   +   R+K   I     
Sbjct: 5775 ---LQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANVKSSAHLRVKPRVIG---- 5825

Query: 1572 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYF 1631
              +L  L D VT+  G+     C +  +  P V W    K L   D    + E G+    
Sbjct: 5826 --LLRPLKD-VTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSE-GKVHTL 5880

Query: 1632 TINGVSTADSGKYGLVVKN 1650
            T+  V   D+G+  L  K+
Sbjct: 5881 TLRDVKLEDAGEVQLTAKD 5899



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 2/95 (2%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             V  + G+ + +     G PPP V+W K+EK L SD   +++     ++  TI  V+  D+
Sbjct: 20909 VIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDT 20967

Query: 1642  GKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALE 1676
             GKY L ++N  G E    TVSV + +  A    L+
Sbjct: 20968 GKYILTIENGVG-EPKSSTVSVKVLDTPAACQKLQ 21001



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 34/122 (27%), Positives = 61/122 (50%), Gaps = 7/122 (5%)

Query: 1544  VDLSGQA-YDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPP 1602
             V++ G + Y E+ AE + +++  I +   A     L   VTI+ G +L L  +V G PPP
Sbjct: 23048 VNVKGMSEYSESIAEIEPVERIEIPDLELA---DDLKKTVTIRAGASLRLMVSVSGRPPP 23104

Query: 1603  EVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVS 1662
              ++W K    LAS    +        +   ++ V+  D+GKY +  +N+ G +++   V 
Sbjct: 23105 VITWSKQGIDLASRAIID---TTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 23161

Query: 1663  VF 1664
             V+
Sbjct: 23162 VY 23163



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 152/790 (19%), Positives = 286/790 (36%), Gaps = 153/790 (19%)

Query: 997  KISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLV 1056
            KIS  K    Y+  +A   +A L     +S     ++ T +V  P  ++K SE R     
Sbjct: 774  KISVPKTEHGYEASIAGSAIATL--QKELSATSSAQKITKSVKAP--TVKPSETR----- 824

Query: 1057 LQWKPPVHSGRTPVTGY-FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRV 1115
                  V +  TP+  + F D  +    E       E  +      VR  +  V +    
Sbjct: 825  ------VRAEPTPLPQFPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREA 878

Query: 1116 RAINQAGVGKPSDLAGPVVAETR-PGTKEVVVNVDDDGVISLNFECD-KMTPKSEFSWSK 1173
            +    A V  P ++  PV   T   G K V V   +    S+  EC     P    +W +
Sbjct: 879  KVTETARVPAPVEI--PVTPPTLVSGLKNVTVIEGE----SVTLECHISGYPSPTVTWYR 932

Query: 1174 DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS--YL---IDEE- 1227
            +    E S   ++  +    ++  ++   +D G ++C   +  G  S+  YL   + EE 
Sbjct: 933  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF 992

Query: 1228 -------------ELKRLL----------ALSHEHKFPTVP-----VKSELAVEILEKGQ 1259
                         E KR +          +L+ E   P  P     +   +  +++E G 
Sbjct: 993  EKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGS 1052

Query: 1260 VRFWMQAEKLSGNAKVNYIFNEKEI--FEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
            V F  Q   + GN K +  + +  +    G +YK+  ++ TG  ++ +     +D G YT
Sbjct: 1053 VVFGCQ---VGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYT 1109

Query: 1318 FQLQDGKATNHSTVVLVGD----VFKKLQKEAEFQRQEWIRKQGPHFVE------YLSWE 1367
              +++      ++  L+ +    +  K Q+E  +Q Q     Q P   E      Y  +E
Sbjct: 1110 IVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYE 1169

Query: 1368 VTGECN-VLLKCKVANIKKETHIV-WYKDEREISVDEKHDFKDGICTLLITEFSKKDAGI 1425
               E    L++ K+A   K+T +V  Y +++E  +     F++ +   +     K     
Sbjct: 1170 KEYEKEQALIRKKMA---KDTVVVRTYVEDQEFHISS---FEERLIKEIEYRIIKTTL-- 1221

Query: 1426 YEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQS----TAEGIQLYSFV 1481
             E +L++D G++K  + + +    E           S  D +I++       G+  +  +
Sbjct: 1222 -EELLEED-GEEKMAVDISESEAVE-----------SGFDSRIKNYRILEGMGVTFHCKM 1268

Query: 1482 TYYVEDLKVNWSHNGSAIRYSDRVKTGVTGE-QIWLQINEPTPNDKGKYVM--------E 1532
            + Y    K+ W  +G  I++ +R +     + +  L+I    P D+G Y           
Sbjct: 1269 SGYPLP-KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNA 1327

Query: 1533 LFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR--------------------- 1571
            +  GK   +    L    Y        R++  +    +R                     
Sbjct: 1328 ICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMS 1387

Query: 1572 -ARVLGGL---------------------PDVVTIQEGKALNLTCNVWGDPPPEVSWLKN 1609
             AR+  G                      P      EG+       V G P PE  W  +
Sbjct: 1388 PARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHD 1447

Query: 1610 EKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEE 1669
             + + +D    +  +   T    I   + +DSG++ +V +N+ G  +    ++V   E +
Sbjct: 1448 GQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQ 1507

Query: 1670 ARMAALESLK 1679
             +   +E LK
Sbjct: 1508 VKPMFVEKLK 1517



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 41/205 (20%), Positives = 77/205 (37%), Gaps = 33/205 (16%)

Query: 1358  PHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFK---DGICTLL 1414
             P   ++L  E + E   L     +++ +   + WYKD +++  +    F    DG   L 
Sbjct: 26346 PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 26405

Query: 1415  ITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTA-- 1472
             I   ++ D G Y   +  + G  K+ L+ + +AFK +  +V K      +D K   +   
Sbjct: 26406 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVT 26465

Query: 1473  --------EGIQLYSFVTYYVEDLKVN--------------------WSHNGSAIRYSDR 1504
                     E I     +   ++D  V+                    W+ +G AI    +
Sbjct: 26466 RKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGK 26525

Query: 1505  VKTGVTGEQIWLQINEPTPNDKGKY 1529
              K        +L+I++   +D G Y
Sbjct: 26526 YKLSEDKGGFFLEIHKTDTSDSGLY 26550



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 64/306 (20%), Positives = 122/306 (39%), Gaps = 34/306 (11%)

Query: 184   STASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKV 243
             S++ K T  + + T +++ +  K S  + Q  A  Q  +S++A  + + + +  K   K+
Sbjct: 26562 SSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKL 26621

Query: 244   VIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGW 303
              ++E+A ++ +    EE +   A   E  ++H  E I K    T    E V+ H  I   
Sbjct: 26622 ALKEEASKVLIS---EEVKKSAATSLEKSIVH--EEITK----TSQASEEVRTHAEIKA- 26671

Query: 304   PEPRVTWYKNQVPINVHANPGKYIIESRYGMHT---LEINGCDFEDTAQYRASAMNVKGE 360
                    +  Q+ IN      + ++++     T     +NG +  ++ +YR         
Sbjct: 26672 -------FSTQMSIN---EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYG------- 26714

Query: 361   LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGE 420
             +S     +  +     DE      + T     G+    Y         D          +
Sbjct: 26715 VSGSDQTLTIKQASHRDEGILTCISKTKE---GIVKCQYDLTLSKELSDAPAFISQPRSQ 26771

Query: 421   TMSLGCRVVITPEIK-HFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 479
              ++ G  V+ T EI     PEI+W++N +P+S S  V    S    +L   + +  D G 
Sbjct: 26772 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26831

Query: 480   YTIRVR 485
             YTI+ +
Sbjct: 26832 YTIKAK 26837



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 46/190 (24%), Positives = 78/190 (41%), Gaps = 28/190 (14%)

Query: 1492 WSHNGSAI--RYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQ 1549
            W H+G  I   Y+ +V     G Q  L I   TP+D G++ +   +       +V L+ +
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDGTQS-LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1502

Query: 1550 AYDEAYAEF--QRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWL 1607
            A +        ++LK                   V I+EG  L +     G+P P++ WL
Sbjct: 1503 AVEHQVKPMFVEKLKN------------------VNIKEGSRLEMKVRATGNPNPDIVWL 1544

Query: 1608 KNEKALASDDHCNLKFEAGR-TAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFI- 1665
            KN   +    +  ++ E  +  A   I+   + DS  Y     NK G +T+   V+V + 
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604

Query: 1666 ---PEEEARM 1672
               PE E ++
Sbjct: 1605 FAEPEPERKL 1614



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 5/91 (5%)

Query: 1582 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD--DHCNLKFEAGRTAYFTINGVSTA 1639
            V + EG       ++ G P PEVSW ++ + +++       + F  GR A  TI  V+ A
Sbjct: 15   VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR-AKLTIPAVTKA 73

Query: 1640 DSGKYGLVVKNKYGSETSDFTVSVFIPEEEA 1670
            +SG+Y L   N  G  TS  T  + +  E A
Sbjct: 74   NSGRYSLKATNGSGQATS--TAELLVKAETA 102



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 47/180 (26%), Positives = 77/180 (42%), Gaps = 16/180 (8%)

Query: 277  PEFIIKPRSHTVW-EKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY-GM 334
            P  II P   TV  E +  +  C ++G  + +V+WY     I     P ++   +++   
Sbjct: 3298 PPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIK----PSRFFRMTQFEDT 3352

Query: 335  HTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGV 394
            + LEI     ED   Y   A N  G++S+ A++ ++ +    + T       ++ +SF  
Sbjct: 3353 YQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKK 3412

Query: 395  TPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSK 454
             P G    F I       V     GET+    RV   P     +PEIQW+ N   + P+K
Sbjct: 3413 EPLGQKPSF-IQPLSSLRV---HNGETVRFHARVSGIP-----KPEIQWFHNQQLILPTK 3463



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             DV+T++ G+ + +   V G P P+++W K  K L  +   +L  +  R     I     A
Sbjct: 11544 DVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE-LQIKEAVRA 11602

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             D GKY +  KN  G       V+V
Sbjct: 11603 DHGKYIISAKNSSGHAQGSAIVNV 11626



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  VV ++    L L   + G P PEV W K E  L   D   ++  +  T    I+ V+
Sbjct: 18741 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT--DRAQIEVTSSFTM-LVIDNVT 18797

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG+Y L ++N  GS+T+   V V
Sbjct: 18798 RFDSGRYNLTLENNSGSKTAFVNVRV 18823



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 56/255 (21%), Positives = 97/255 (38%), Gaps = 41/255 (16%)

Query: 238  KKSRKVVIREKAERLSLRKTLEETE---TYHAKLNEDHLL------HAPEFIIKPRSHTV 288
            ++  K V+  +  R+ + +T +      T+ A  N   +         P+ + + +  TV
Sbjct: 3145 QERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTV 3204

Query: 289  WEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTA 348
               +  +    I+G P+P+++WYK +  ++      K++ + +   +TL +     ED A
Sbjct: 3205 QSGKPARFCAVISGRPQPKISWYKEEQLLST-GFKCKFLHDGQ--EYTLLLIEAFPEDAA 3261

Query: 349  QYRASAMNVKG--ELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
             Y   A N  G    SA  SV V        E   +  A   PL   VT  G  +RF+  
Sbjct: 3262 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQ-- 3319

Query: 407  FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                               CRV  T        ++ WY     + PS++ +     +   
Sbjct: 3320 -------------------CRVSGT------DLKVSWYSKDKKIKPSRFFRMTQFEDTYQ 3354

Query: 467  LTFSHLNKEDEGLYT 481
            L  +    EDEG YT
Sbjct: 3355 LEIAEAYPEDEGTYT 3369



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 83/367 (22%), Positives = 145/367 (39%), Gaps = 60/367 (16%)

Query: 1181 SPRLEVESKGNKTKMTFKDLGMDDLG--IYSCDVTDTDGIASSYLIDEEELKRLLALSHE 1238
            SP  E++++G K  +T   + +D  G  +Y      T  I +   + E EL         
Sbjct: 5067 SPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILT---VKEIELDF------- 5116

Query: 1239 HKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNT 1298
                 VP+K    V + E+ Q RF      L+  A V +      I    K+ +  D   
Sbjct: 5117 ----AVPLKD---VTVPERRQARFECV---LTREANVIWSKGPDIIKSSDKFDIIADGKK 5166

Query: 1299 GIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGP 1358
             I+   +   Q +DEG YT +++ GK T  S  + V  +  K     E Q  +       
Sbjct: 5167 HIL--VINDSQFDDEGVYTAEVE-GKKT--SARLFVTGIRLKFMSPLEDQTVK------- 5214

Query: 1359 HFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEF 1418
                       GE    + C++++ K   H+VW+K++ ++             T+LI+  
Sbjct: 5215 ----------EGETATFV-CELSHEKM--HVVWFKNDAKLHTSR---------TVLISSE 5252

Query: 1419 SKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY 1478
             K      + +  DD  + K+++K +    +  ++E      +   D K     + I L 
Sbjct: 5253 GKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHD-KTAVEKDEITLK 5311

Query: 1479 SFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKT 1538
              V+   +D+ V W  +G  I  S +      G +  L+I +    DKG+YV +    KT
Sbjct: 5312 CEVS---KDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKT 5368

Query: 1539 GHQKTVD 1545
                TV+
Sbjct: 5369 KANVTVE 5375



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEA-GRTAYFTINGV 1636
             L  V+T++ G  + L   V G P PEV+W K++ A        +K +    ++ F++   
Sbjct: 11835 LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKA 11894

Query: 1637  STADSGKYGLVVKNKYGSETSDFTVSV 1663
               +D GKY +   N  GS  +  TV+V
Sbjct: 11895 KRSDGGKYVVTATNTAGSFVAYATVNV 11921



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 5/116 (4%)

Query: 1552  DEAYAEFQRLKQAAIAEKNR----ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWL 1607
             D  Y+E +    + I ++ +    A + G    ++T + G    +   + G P P+V+W 
Sbjct: 22251 DAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWK 22310

Query: 1608  KNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               E  L   D  ++     RT   T+      DSG+Y L ++N  G +T   TV V
Sbjct: 22311 LEEMRLKETDRVSITTTKDRTT-LTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22365



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G+   L  +V G P P + WL+ +K +     C +K      A   +      
Sbjct: 17261 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIRI 17319

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             D G+Y L   N  GS++    V V
Sbjct: 17320 DGGQYILRASNVAGSKSFPVNVKV 17343



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 1/94 (1%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P F+ K ++  + E   +++     G P P + W KN   I  H  P K  IE   G   
Sbjct: 1510 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYP-KIRIEGTKGEAA 1568

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            L+I+    +D+A Y A+A+N  G  +    V V+
Sbjct: 1569 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 66/302 (21%), Positives = 111/302 (36%), Gaps = 30/302 (9%)

Query: 224  KQATSALQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKP 283
            K+ +S+    E     S ++ + +  E L L   L E+  Y  K + +     P FI + 
Sbjct: 3532 KEFSSSFLSAEEEGLHSAELQLSKINETLEL---LSESPVYPTKFDSEKEGTGPIFIKEV 3588

Query: 284  RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
             +  +   +   L  ++ G P+P++ W+ N V +   A+  K++ +     H+L I    
Sbjct: 3589 SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSAD-YKFVFDG--DDHSLIILFTK 3645

Query: 344  FEDTAQYRASAMNVKGE--LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYAS 401
             ED  +Y   A N  G+   SAY  +  K    +  ET      S   L     P     
Sbjct: 3646 LEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP----- 3700

Query: 402  RFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS 461
                HF  +       +G        VV  P      P + W++    L  S +   + +
Sbjct: 3701 ----HFLKELKPIRCAQGLPAIFEYTVVGEP-----APTVTWFKENKQLCTSVYYTIIHN 3751

Query: 462  -GERATLTFSHLNKEDEGLYTIRVR--MGEYYEQYSAYVFVRDAD-----AEIEGAPAAP 513
                 T   +   +ED GLY  +    +GE        V + D D      + +  P AP
Sbjct: 3752 PNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAP 3811

Query: 514  LD 515
             D
Sbjct: 3812 ED 3813



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 43/211 (20%), Positives = 77/211 (36%), Gaps = 25/211 (11%)

Query: 1468 IQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPND-K 1526
            + + +E   +    T      +VNW      +   ++ K         L I++    D +
Sbjct: 4375 VDTVSEEGDIVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQ 4434

Query: 1527 GKYVMELFD--GKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTI 1584
            G+YV E  +  GKT                 A+   +K+AA   K +   L        +
Sbjct: 4435 GEYVCEALNDSGKTATS--------------AKLTVVKRAAPVIKRKIEPL-------EV 4473

Query: 1585 QEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKY 1644
              G     TC +   P     W K  + +   D C+++  +   +   I      D G+Y
Sbjct: 4474 ALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR-SSKYISSLEILRTQVVDCGEY 4532

Query: 1645 GLVVKNKYGSETSDFTVSVFIPEEEARMAAL 1675
                 N+YGS +   T++V +P  E ++  L
Sbjct: 4533 TCKASNEYGSVSCTATLTVTVPGGEKKVRKL 4563



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 72/365 (19%), Positives = 133/365 (36%), Gaps = 62/365 (16%)

Query: 124  LSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKE----AAAYIAQRNLLASEEGIT 179
            L G++ E  PSD +VP   G+  H   + D + E   E    A  +    NL   E  + 
Sbjct: 5858 LKGKKLE--PSDKVVPRSEGKV-HTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVE 5914

Query: 180  TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
             +K           +  T  + +TA  +   SR++   +      +   + + E  ++ +
Sbjct: 5915 FTKPL---------EDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGR 5965

Query: 240  SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
             RK+VI +      ++    + + +    N + +    EF+       V EKE  +  C 
Sbjct: 5966 VRKLVIHDCTPE-DIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECE 6024

Query: 300  IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
            ++     +V W+K+   I       KY I S+  +  L IN C  +D A+Y       + 
Sbjct: 6025 LSR-ENAKVKWFKDGAEIK---KGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTAR- 6079

Query: 360  ELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREG 419
              S   +V+        +E  F    + + +S                          E 
Sbjct: 6080 -TSGMLTVLE-------EEAVFTKNLANIEVS--------------------------ET 6105

Query: 420  ETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 479
            +T+ L C      E+     E+ WY+    +  +   + L  G +  L   + + ED G 
Sbjct: 6106 DTIKLVC------EVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6159

Query: 480  YTIRV 484
            Y  R+
Sbjct: 6160 YNCRL 6164



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 2/84 (2%)

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
            D++ I EG+ L++       P P VSW K+ K + + D   +K +   +A+  +     A
Sbjct: 8023 DIIVI-EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKND-HISAHLEVPKSVRA 8080

Query: 1640 DSGKYGLVVKNKYGSETSDFTVSV 1663
            D+G Y + ++NK GS T+   V V
Sbjct: 8081 DAGIYTITLENKLGSATASINVKV 8104



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 50/209 (23%), Positives = 82/209 (39%), Gaps = 25/209 (11%)

Query: 286   HTVWEKE-NVKLHCSIAGWPEP-RVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
             H V E+  +VK  C I  + +  +VTWY     +    N  KY I    G+  L +    
Sbjct: 25204 HAVGEEGGHVKYVCKIENYDQSTQVTWYFG---VRQLENSEKYEITYEDGVAILYVKDIT 25260

Query: 344   FEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASR- 402
               D   YR   +N  GE S+YA + VK  +  +D   ++   +   +           R 
Sbjct: 25261 KLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYD---YYCRRTMKKIKRRTDTMRLLERP 25317

Query: 403   --FEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSP----SKWV 456
               F +   +K        GE +  G  + + PE     P + WY++G  + P     K+ 
Sbjct: 25318 PEFTLPLYNK----TAYVGENVRFGVTITVHPE-----PHVTWYKSGQKIKPGDNDKKYT 25368

Query: 457   QTLWSGERATLTFSHLNKEDEGLYTIRVR 485
                  G    LT + +  +D+  YT+  R
Sbjct: 25369 FESDKG-LYQLTINSVTTDDDAEYTVVAR 25396



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G++  +  +++G P P + W+K ++ L++     +K     T+  ++      
Sbjct: 16179 DTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATS-LSVKDAVRV 16237

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             DSG Y L  KN  G  +    V V
Sbjct: 16238 DSGNYILKAKNVAGERSVTVNVKV 16261



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 5/96 (5%)

Query: 290   EKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQ 349
             E ++V     ++G P P + W K+  P+++   P   II      + L I     EDT  
Sbjct: 25436 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSL--GPNIEIIHEGLDYYALHIRDTLPEDTGY 25493

Query: 350   YRASAMNVKGELSAYASVVVKRY---KGEFDETRFH 382
             YR +A N  G  S  A + V+R    K EF     H
Sbjct: 25494 YRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEH 25529



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 1/81 (1%)

Query: 1583  TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
             +IQ G+ L +   V G P P +SW+K+ + L      N++  A  T      G +  D G
Sbjct: 17950 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEG-NKDDFG 18008

Query: 1643  KYGLVVKNKYGSETSDFTVSV 1663
             KY +   N  G+ T + +V V
Sbjct: 18009 KYTVTATNSAGTATENLSVIV 18029



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 40/166 (24%), Positives = 64/166 (38%), Gaps = 21/166 (12%)

Query: 1492 WSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAY 1551
            W  +GS IR S + +    G+   L I +   +D G+Y   L  G      T  L     
Sbjct: 4779 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKL----- 4833

Query: 1552 DEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEK 1611
                          + E+   R +  L + VT+ +G+ L L+C +  +   +V W K+ K
Sbjct: 4834 --------------VVEELPVRFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGK 4877

Query: 1612 ALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETS 1657
             +       +    G     TIN     D+G Y + V+N    E S
Sbjct: 4878 IVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECS 4923



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 61/309 (19%), Positives = 119/309 (38%), Gaps = 50/309 (16%)

Query: 1143 EVVVNVDDDGVISLN---FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKD 1199
            E V +++D  V   +   F C     K+   W ++    ++  + + E  G+  ++  KD
Sbjct: 6452 EFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6511

Query: 1200 LGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVK-SELAVEILEKG 1258
              +DD   Y+C V D    A  ++ +                  +PV+      +ILE  
Sbjct: 6512 CRLDDECEYACGVEDRKSRARLFVEE------------------IPVEIIRPPQDILEAP 6553

Query: 1259 QVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTF 1318
                   AE      +V ++ N   + +G K++M  +    I  + +  ++  D+G Y F
Sbjct: 6554 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGK--IHRLQICDIKPRDQGEYRF 6611

Query: 1319 QLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKC 1378
              +D +A     +     +     K A+   Q+ +   G      + ++           
Sbjct: 6612 IAKDKEARAKLELAAAPKI-----KTAD---QDLVVDVGKPLTMVVPYD----------- 6652

Query: 1379 KVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDK 1438
              A  K E    W+K+   +S  +  D      +  I E  K D G Y+++L++  GK +
Sbjct: 6653 --AYPKAEAE--WFKENEPLST-KTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAE 6707

Query: 1439 S--RLKLVD 1445
                LK++D
Sbjct: 6708 GFINLKVID 6716



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST- 1638
             D V ++ G+A  L  +V G PPP + W K+ K L       +K     T    +N  ST 
Sbjct: 15097 DTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN--LVNKDSTR 15154

Query: 1639  ADSGKYGLVVKNKYGSETSDFTVSV 1663
              DSG Y L   N  G     F V V
Sbjct: 15155 RDSGAYTLTATNPGGFAKHIFNVKV 15179



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 36/155 (23%), Positives = 63/155 (40%), Gaps = 16/155 (10%)

Query: 1510  TGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEK 1569
             +G+  W + N+    DK   +  L +         +   + + E      R ++ A++ K
Sbjct: 24100 SGDSAWKKSNKERIKDKQFTIGGLLEA-------TEYEFRVFAENETGLSRPRRTAMSIK 24152

Query: 1570  NRARVLGGLPDV------VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKF 1623
              +    G  P +      VT + G+A  L+C + G P P++ W +  K L       +  
Sbjct: 24153 TKL-TSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSS 24211

Query: 1624  EAGRTAYFTINGVSTADSGKYGLVVKNKYGS-ETS 1657
             + GRT   T+      D G Y  +  N+ G  ETS
Sbjct: 24212 D-GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 24245



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 112/546 (20%), Positives = 188/546 (34%), Gaps = 108/546 (19%)

Query: 1110 SYVFRVRAINQAGVGKPSDLAGPVVAETRP-----GTKEVVVNVDDDGVISLNFECDKMT 1164
            +Y F + A+  +  G+ S  +  V+   +      GTK V+             EC    
Sbjct: 2378 NYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVL-------------ECKVSV 2424

Query: 1165 PK-SEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            P  +   W  +    +   R++   KG K ++        D G Y   V     + ++  
Sbjct: 2425 PDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIV---GRVETNCN 2481

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
            +  E++K +  L       T  V  E  VE+   G    W               F +KE
Sbjct: 2482 LSVEKIKIIRGLRDLTCTETQNVVFE--VELSHSGIDVLWN--------------FKDKE 2525

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQK 1343
            I    KYK  I+ +  I ++ +  +  +DEG YTF   +   +   TV   G + K L  
Sbjct: 2526 IKPSSKYK--IEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVA-GGAISKPLTD 2582

Query: 1344 EAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEK 1403
            +   + QE                       + +C+VAN   ++   W +D + + +   
Sbjct: 2583 QTVAESQE----------------------AVFECEVAN--PDSKGEWLRDGKHLPLTNN 2618

Query: 1404 -HDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALS 1462
                 DG    LI   +K D  I E   K    K  ++LK+  EA          KI  +
Sbjct: 2619 IRSESDGHKRRLIIAATKLD-DIGEYTYKVATSKTSAKLKV--EAV---------KIKKT 2666

Query: 1463 ATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPT 1522
              +L +  T + +         V+   V W  NG  +  +++    V G    L+I    
Sbjct: 2667 LKNLTVTETQDAVFTVELTHPNVKG--VQWIKNGVVLESNEKYAISVKGTIYSLRIKNCA 2724

Query: 1523 PNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVV 1582
              D+  Y   L  G+ G    +                ++   I +K         P  V
Sbjct: 2725 IVDESVYGFRL--GRLGASARL---------------HVETVKIIKK---------PKDV 2758

Query: 1583 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
            T  E   +    +V  D  P V W      +   D   L  E  +     +  +S +D+G
Sbjct: 2759 TALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSER-KVHKLMLQNISPSDAG 2816

Query: 1643 KYGLVV 1648
            +Y  VV
Sbjct: 2817 EYTAVV 2822



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  VVTI+    L L   + G P PEV W ++     S D  +++  +  T    +  V+
Sbjct: 15494 LRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGE--SLDKASIESTSSYTLLI-VGNVN 15550

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSGKY L V+N  GS+++   V V
Sbjct: 15551 RFDSGKYILTVENSSGSKSAFVNVRV 15576



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  ++ I+ G +L L   + G P PEV W K +  +   D   +   +  T+   ++ V+
Sbjct: 16576 LRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIR--DAAIIDVTSSFTS-LVLDNVN 16632

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSGKY L ++N  G++++  TV V
Sbjct: 16633 RYDSGKYTLTLENSSGTKSAFVTVRV 16658



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 7/82 (8%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEK--ALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             ++ G ++ L     G P P   W K +   +L +D H    F        T+   +  D+
Sbjct: 21997 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST-----LTVENCNRNDA 22051

Query: 1642  GKYGLVVKNKYGSETSDFTVSV 1663
             GKY L V+N  GS++  FTV V
Sbjct: 22052 GKYTLTVENNSGSKSITFTVKV 22073



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 6/78 (7%)

Query: 1356  QGPHFVEYL-SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVD----EKHDFKDGI 1410
             Q PHF E L +  V  + N  L CKV    K   + WY+  +EI  D       +FK G 
Sbjct: 24554 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI-VKWYRQGKEIIADGLKYRIQEFKGGY 24612

Query: 1411  CTLLITEFSKKDAGIYEV 1428
               L+I   +  DA +Y+V
Sbjct: 24613 HQLIIASVTDDDATVYQV 24630



 Score = 39.7 bits (91), Expect = 0.025
 Identities = 34/135 (25%), Positives = 52/135 (38%), Gaps = 9/135 (6%)

Query: 245   IREKAERLSL-----RKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENV-KLHC 298
             I EK  ++S      +KT E T T   +      + +   I+     T    ++V K   
Sbjct: 26442 IHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAV 26501

Query: 299   SIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVK 358
                G P P   W K+   I      GKY +    G   LEI+  D  D+  Y  +  N  
Sbjct: 26502 KATGEPRPTAIWTKDGKAIT---QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSA 26558

Query: 359   GELSAYASVVVKRYK 373
             G +S+   + +K  K
Sbjct: 26559 GSVSSSCKLTIKAIK 26573



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 36/157 (22%), Positives = 63/157 (40%), Gaps = 10/157 (6%)

Query: 1511 GEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKN 1570
            G   W+   EP    K + V  L +GK    +   L+ Q   +     + ++     E  
Sbjct: 7258 GSDKWVACGEPVAETKME-VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAP 7316

Query: 1571 R----ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG 1626
                  ++L GL    T++ G  + L   V G P P+++W K +  L  D    ++    
Sbjct: 7317 EIFLDVKLLAGL----TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVP 7371

Query: 1627 RTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
            + +  TI     +D+G Y +   N  G  T+   V+V
Sbjct: 7372 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7408



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 11/191 (5%)

Query: 180   TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
             TS Q + S Q   S Q +ASKQ  +    ++S  S+ +     S  A S    +E+  + 
Sbjct: 26870 TSLQGSFSSQ---SVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEM 26926

Query: 240   SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
             S    +      +S    LE + +   K     +   P+    P   ++ E + + + C+
Sbjct: 26927 SSSSFMG-----ISNMTQLESSTSKMLKAGIRGI--PPKIEALPSDISIDEGKVLTVACA 26979

Query: 300   IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
               G P P VTW      I+     G++ IE+   + TL I     +D   Y  S  N  G
Sbjct: 26980 FTGEPTPEVTWSCGGRKIH-SQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 27038

Query: 360   ELSAYASVVVK 370
               SA  ++ ++
Sbjct: 27039 SDSATVNIHIR 27049



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 54/228 (23%), Positives = 97/228 (42%), Gaps = 27/228 (11%)

Query: 144  RQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQT-----TASKQSTA 198
            R KH  G T      ++EA   +    L+ S++ +    Q TA  Q      TA     +
Sbjct: 1113 RNKH--GETSASASLLEEADYEL----LMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYS 1166

Query: 199  SKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRKTL 258
              +    K+    R+  A    VV     + ++ +E       + +I+E   R+ ++ TL
Sbjct: 1167 EYEKEYEKEQALIRKKMAKDTVVVR----TYVEDQEFHISSFEERLIKEIEYRI-IKTTL 1221

Query: 259  EET------ETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYK 312
            EE       E     ++E   + +  F  + +++ + E   V  HC ++G+P P++ WYK
Sbjct: 1222 EELLEEDGEEKMAVDISESEAVESG-FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYK 1280

Query: 313  NQVPINVHANPGKYIIE-SRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
            +   I    +  +Y ++  + G  +L I     ED   Y A A N+KG
Sbjct: 1281 DGKRIK---HGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1325



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 63/315 (20%), Positives = 110/315 (34%), Gaps = 43/315 (13%)

Query: 171  LLASEEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSA- 229
            +L  +EGI T+  S        S +      +     +        SR   +S ++ S  
Sbjct: 1308 VLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRS 1367

Query: 230  -LQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTV 288
             ++        +R    R    R+S  + LEET+      ++   L+ P F++KP S   
Sbjct: 1368 PIRMSPARMSPARMSPARMSPARMSPGRRLEETDE-----SQLERLYKPVFVLKPVSFKC 1422

Query: 289  WEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTA 348
             E +  +    + G P P   W+ +   I V+    K +I+   G  +L I      D+ 
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQI-VNDYTHKVVIKED-GTQSLIIVPATPSDSG 1480

Query: 349  QYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFD 408
            ++   A N  G  S    + V+  + +                  V P          F 
Sbjct: 1481 EWTVVAQNRAGRSSISVILTVEAVEHQ------------------VKPM---------FV 1513

Query: 409  DKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGER--AT 466
            +K      +EG  + +  R    P      P+I W +N   + P K+ +    G +  A 
Sbjct: 1514 EKLKNVNIKEGSRLEMKVRATGNP-----NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAA 1568

Query: 467  LTFSHLNKEDEGLYT 481
            L       +D   YT
Sbjct: 1569 LKIDSTVSQDSAWYT 1583



 Score = 38.5 bits (88), Expect = 0.056
 Identities = 76/371 (20%), Positives = 137/371 (36%), Gaps = 83/371 (22%)

Query: 231  QQEETSEKKSRKVVIREKAERLSLRK--TLEETETYHAKLNEDH------LLHAPEFIIK 282
            + ++T E   +  VI +  +R+ + K  TL++  TY   +          ++     ++ 
Sbjct: 6214 RDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVP 6273

Query: 283  PRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGC 342
             +   V E++ V  +C +      +  W++N+  I    +  KYII  +  ++TL I   
Sbjct: 6274 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAI---FDSSKYIILQKDLVYTLRIRDA 6329

Query: 343  DFEDTAQYRASAMNVKGE-LSAYASVVVKR------------YKGEFDETRFHAGASTMP 389
              +D A Y  S  N +GE + + A+++V+                E     F    + + 
Sbjct: 6330 HLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLN 6389

Query: 390  LSFGVTPYGYASRFEIHFD-------DKF-------DVSFGREGETM-------SLGCRV 428
            ++   T  G     E+ FD       DK+       D  F  EGE +       S+   +
Sbjct: 6390 VTLKWTKNGE----EVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELL 6445

Query: 429  VI---TPEIKHFQPE--------------------IQWYRNGVPLSPSKWVQTLWSGERA 465
            +I   T  ++H + +                    ++WYRNG  +   K  +    G   
Sbjct: 6446 IIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIH 6505

Query: 466  TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLD------VKCL 519
             L       +DE  Y      G    +  A +FV +   EI   P   L+      V   
Sbjct: 6506 RLIIKDCRLDDECEYA----CGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLA 6561

Query: 520  EANKDYIIISW 530
            E NKD + + W
Sbjct: 6562 ELNKDKVEVQW 6572



 Score = 38.5 bits (88), Expect = 0.056
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 5/105 (4%)

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKAL--ASDDHCNLKFEAGRTAYFTINGVS 1637
            D + ++ G+ +++  +V G P P++ W KNE  +   +D     K E  R+   T   + 
Sbjct: 9034 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 9093

Query: 1638 TA---DSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLK 1679
             A   D G Y +   N+ GS   +  V V+      R  A+  +K
Sbjct: 9094 KAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIK 9138



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 27/122 (22%), Positives = 55/122 (45%), Gaps = 7/122 (5%)

Query: 1532 ELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALN 1591
            +L +G+ G Q+  +L   A++ A       ++    EK +  ++   P+ V + EG+   
Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQK----EKQKPDIVL-YPEPVRVLEGETAR 1813

Query: 1592 LTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNK 1651
              C V G P P+V+W  N + +       ++++     Y  I    + D+G+  +  +N 
Sbjct: 1814 FRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG--IHYLDIVDCKSYDTGEVKVTAENP 1871

Query: 1652 YG 1653
             G
Sbjct: 1872 EG 1873



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 36/174 (20%), Positives = 69/174 (39%), Gaps = 20/174 (11%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            F C+    K    W K+      S  + + S+G   K+  K++ +DD+      V +   
Sbjct: 5221 FVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSS 5280

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
             A   +++ +             + TV +  + AV   EK ++    +  K   +  V +
Sbjct: 5281 TAQLKVLEAD------------PYFTVKLHDKTAV---EKDEITLKCEVSK---DVPVKW 5322

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTV 1331
              + +EI   PKY +  D    I++  ++K   +D+G Y       K   + TV
Sbjct: 5323 FKDGEEIVPSPKYSIKADGLRRILK--IKKADLKDKGEYVCDCGTDKTKANVTV 5374



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 1/83 (1%)

Query: 1581  VVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTAD 1640
             +V  + G  + +   V G P P V+W K ++ L      N +  A  T    IN    +D
Sbjct: 14702 LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST-ILNINECVRSD 14760

Query: 1641  SGKYGLVVKNKYGSETSDFTVSV 1663
             SG Y L  +N  G      T+ V
Sbjct: 14761 SGPYPLTARNIVGEVGDVITIQV 14783



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 18/77 (23%), Positives = 36/77 (46%)

Query: 1587  GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
             G+ +++     G P P ++W K +  + ++ H  +      T+    NGV   D+G Y +
Sbjct: 24670 GEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVV 24729

Query: 1647  VVKNKYGSETSDFTVSV 1663
               KN++G +     + V
Sbjct: 24730 CAKNRFGIDQKTVELDV 24746



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 21/84 (25%), Positives = 33/84 (39%), Gaps = 3/84 (3%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G  + +   V G PPP V+W  NE+ L  +           ++   I     +
Sbjct: 10160 DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIE---TTAISSSMVIKNCQRS 10216

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
               G Y L+ KN+ G       V V
Sbjct: 10217 HQGVYSLLAKNEAGERKKTIIVDV 10240



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             +  ++T++ G  + L   V+G P P VSW K+   L   +   +  +        +  V+
Sbjct: 12929 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR-NLCTLELFSVN 12987

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG Y +  +N  GS+++   + V
Sbjct: 12988 RKDSGDYTITAENSSGSKSATIKLKV 13013



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 1583  TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
             ++Q G+ L +   + G P P ++W K+   L      N+      T   +I      D G
Sbjct: 16868 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT-LSIKETHKDDGG 16926

Query: 1643  KYGLVVKNKYGSETSDFTV 1661
             +YG+ V N  G +T+   +
Sbjct: 16927 QYGITVANVVGQKTASIEI 16945



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             + +  G+ + L   + G PPP  SW      L   +   ++    + A  TI   +  D+
Sbjct: 23376 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT-KVAKLTIRETTIRDT 23434

Query: 1642  GKYGLVVKNKYGSETSDFTVSVFI 1665
             G+Y L +KN  G  T+  T+ V I
Sbjct: 23435 GEYTLELKNVTG--TTSETIKVII 23456



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 8/93 (8%)

Query: 1578 LPDVVTIQEGKALNLTCNVWGDPPPEVSWLK-------NEKALASDDHCNLKFEAGRTAY 1630
            L + + ++EG  +N+   + G P P ++W K       N++ +  D H N K     T  
Sbjct: 9750 LKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KLVVDDTCT 9808

Query: 1631 FTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
              I     +D+G Y +   N  G+ + +  ++V
Sbjct: 9809 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9841



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 19/86 (22%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKN-----EKA----LASDDHCNLKFEAGRTAY 1630
             DV+ ++ G+ L +  ++ G P P +SW K+     E+A    +++D+H  L         
Sbjct: 19425 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLL--------- 19475

Query: 1631  FTINGVSTADSGKYGLVVKNKYGSET 1656
              T+      D+G+Y L +KN  G+ +
Sbjct: 19476 -TVKDCIRRDTGQYVLTLKNVAGTRS 19500



 Score = 36.6 bits (83), Expect = 0.21
 Identities = 99/530 (18%), Positives = 188/530 (35%), Gaps = 110/530 (20%)

Query: 1142 KEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLG 1201
            K++++   +    S  FEC      +  +W KD  +  +SP+    + G   K+   D+ 
Sbjct: 4750 KDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQ 4809

Query: 1202 MDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVP-VKSELAVEILEKGQV 1260
            + D G Y+C                     +L L ++ K  T   V  EL V  ++  + 
Sbjct: 4810 LSDAGEYTC---------------------VLRLGNKEKTSTAKLVVEELPVRFVKTLEE 4848

Query: 1261 RFW-MQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGII--------EMFMEKLQDE 1311
                ++ + L  + ++N    E+++      K+ +++   I+         + +    D 
Sbjct: 4849 EVTVVKGQPLYLSCELN---KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDT 4905

Query: 1312 DEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGE 1371
            D GTYT  +++      S+ V V +V +           +W+ K            V  +
Sbjct: 4906 DAGTYTVTVENANNLECSSCVKVVEVIR-----------DWLVK------PIRDQHVKPK 4948

Query: 1372 CNVLLKCKVANIKKETHIVWYKDEREISV---DEKHDFKDG-ICTLLITEFSKKDAGIYE 1427
               +  C +A  K   +I W+K   EI     D+    +DG    L I     +D   Y 
Sbjct: 4949 GTAIFACDIA--KDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYA 5006

Query: 1428 VILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY-----SFVT 1482
            V ++  R                       K+ L   ++++    E + +Y     SF  
Sbjct: 5007 VEIEGKR--------------------YPAKLTLGEREVELLKPIEDVTIYEKESASFDA 5046

Query: 1483 YYVE-DLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQ 1541
               E D+   W   G  +R S   +    G + +L +++   +  G+ + +  +  T   
Sbjct: 5047 EISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAIT--- 5103

Query: 1542 KTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPP 1601
             T  L+ +  +  +A    LK   + E+ +AR      + V  +E               
Sbjct: 5104 -TAILTVKEIELDFA--VPLKDVTVPERRQARF-----ECVLTREA-------------- 5141

Query: 1602 PEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNK 1651
              V W K    + S D  ++    G+     IN     D G Y   V+ K
Sbjct: 5142 -NVIWSKGPDIIKSSDKFDI-IADGKKHILVINDSQFDDEGVYTAEVEGK 5189



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 293   NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352
             ++++   I G P P VTW K+ + +   AN     IE+      L I  C+  DT ++  
Sbjct: 14421 SIRIFVPIKGRPAPEVTWTKDNINLKNRAN-----IENTESFTLLIIPECNRYDTGKFVM 14475

Query: 353   SAMNVKGELSAYASVVV 369
             +  N  G+ S + +V V
Sbjct: 14476 TIENPAGKKSGFVNVRV 14492



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKAL-ASDDHCNLKFEAGRTAYFTINGVST 1638
             DV+ +  G+   L  ++ G P P+V W K+ K L  +     +K    +T     + + T
Sbjct: 18343 DVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRT 18402

Query: 1639  ADSGKYGLVVKNKYGSETSDFTVSV 1663
              D G+Y L + N  G+++   TV V
Sbjct: 18403 -DGGQYILKLSNVGGTKSIPITVKV 18426



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 277 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
           P F+ + +S TV +   V+L   + G P P V +Y++   I    +   + I     +++
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD---FQISQEGDLYS 160

Query: 337 LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
           L I     ED+  Y  +A N  G  ++ A ++V+
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 38/153 (24%), Positives = 61/153 (39%), Gaps = 11/153 (7%)

Query: 221  VVSKQATSALQQEETSEKKSRKVVIREKA-ERLSLRKTLEETETYHAKLNEDHLLHAPEF 279
            V   +  +  + E T  ++ +    R KA  R    K    TE   A   ++    APE 
Sbjct: 7263 VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQE----APEI 7318

Query: 280  IIKPR---SHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
             +  +     TV     ++L  ++ G PEP++TW K  +   +     +  IE+     T
Sbjct: 7319 FLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM---ILKQDKRITIENVPKKST 7375

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
            + I      DT  Y   A+NV G  +A   V V
Sbjct: 7376 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7408



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             +VV  + G ++ L   + G P P + W K++K L ++    ++      A   I      
Sbjct: 20508 EVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRL 20566

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             +SG Y L ++N  GS ++   V +
Sbjct: 20567 NSGCYELKLRNAMGSASATIRVQI 20590



 Score = 35.4 bits (80), Expect = 0.47
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + I+ G++L +   V G P P V+W K+   +    +  +    G T+ F +   +  
Sbjct: 21594 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF-VRDATRD 21652

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
               G Y +  KN  GS  ++  V V
Sbjct: 21653 HRGVYTVEAKNASGSAKAEIKVKV 21676



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 2/64 (3%)

Query: 439 PEIQWYRNGVPLSPS--KWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAY 496
           PE+ W+R+G  +S S    VQ  +S  RA LT   + K + G Y+++   G      +A 
Sbjct: 35  PEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAE 94

Query: 497 VFVR 500
           + V+
Sbjct: 95  LLVK 98



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 1/75 (1%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             + ++ G  +     + G P P   W  +   + +D+H  ++ +   ++  TI      D+
Sbjct: 11148 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETD-NFSSVLTIKNCLRRDT 11206

Query: 1642  GKYGLVVKNKYGSET 1656
             G+Y + V N  GS+T
Sbjct: 11207 GEYQITVSNAAGSKT 11221



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             E++++   + G P PRVTW+K+ V I    N     I    G  +L +     +    Y 
Sbjct: 21602 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDVLGSTSLFVRDATRDHRGVYT 21658

Query: 352   ASAMNVKGELSAYASVVVKRYKGE 375
               A N  G   A   V V+   G+
Sbjct: 21659 VEAKNASGSAKAEIKVKVQDTPGK 21682



 Score = 34.7 bits (78), Expect = 0.80
 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L   + ++ G  + L   V G PPP+++W K    L      ++K       +     V+
Sbjct: 13327 LRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVN 13385

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               D+GKY L ++N  G +     V V
Sbjct: 13386 KYDAGKYILTLENSCGKKEYTIVVKV 13411



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 41/195 (21%), Positives = 77/195 (39%), Gaps = 19/195 (9%)

Query: 1389 IVWYKDEREISVDE----KHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLV 1444
            + W++D + IS       +  F DG   L I   +K ++G Y +   +  G+  S  +L+
Sbjct: 37   VSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELL 96

Query: 1445 ---DEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRY 1501
               + A    +  +        + +++Q    GI     V +Y          +G+ I+ 
Sbjct: 97   VKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPT-PVVKFY---------RDGAEIQS 146

Query: 1502 SDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR- 1560
            S   +    G+   L I E  P D G Y +   +       T +L  Q  +E  A+  + 
Sbjct: 147  SLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKT 206

Query: 1561 -LKQAAIAEKNRARV 1574
             +  A I+E  + R+
Sbjct: 207  IVSTAQISESRQTRI 221



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 7/94 (7%)

Query: 1577 GLPDVVTIQEGKALNLTCNVWGDPPPEVSWL---KNEKALASDDHC---NLKFE-AGRTA 1629
            G  D +  + G  + +   + G P P+ SW    K +KA+    H    + + E A  ++
Sbjct: 9443 GAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSS 9502

Query: 1630 YFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               I     + +GKY +  KNK G +T++  V V
Sbjct: 9503 VIIIPECKRSHTGKYSITAKNKAGQKTANCRVKV 9536



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 5/83 (6%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG-RTAYFTINGVSTAD 1640
             + ++ G +  +     G P PE++W + E          ++ E G      +I+     D
Sbjct: 17662 IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSIDNCDRND 17717

Query: 1641  SGKYGLVVKNKYGSETSDFTVSV 1663
             +GKY L ++N  GS+++  TV V
Sbjct: 17718 AGKYILKLENSSGSKSAFVTVKV 17740



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 10/87 (11%)

Query: 1582 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD----DHCNLKFEAGRTAYFTINGVS 1637
            + I  GK L +   V G P P   W K E  L  D    D+   K E        I    
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSE------LIIKDAL 8795

Query: 1638 TADSGKYGLVVKNKYGSETSDFTVSVF 1664
              D G+Y +   N  GS+ +   V VF
Sbjct: 8796 RKDHGRYVITATNSCGSKFAAARVEVF 8822



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 4/109 (3%)

Query: 1358 PHFVEYL-SWEVTGECNVLLKCKVANIKKETHIVWYKDEREI--SVDEKHDFKDGICTLL 1414
            P+FV+ L S  V     V L+ +V  I     + +Y+D  EI  S+D +   +  + +LL
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV-VKFYRDGAEIQSSLDFQISQEGDLYSLL 162

Query: 1415 ITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSA 1463
            I E   +D+G Y V   +  G+  S  +L+ +  +E+  +  K I  +A
Sbjct: 163  IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTA 211



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 5/67 (7%)

Query: 418  EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDE 477
            EG    L C+V + P++      ++WY N   + P   VQ +  G +  L  +  +  DE
Sbjct: 2412 EGTKAVLECKVSV-PDVT----SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDE 2466

Query: 478  GLYTIRV 484
            G Y + V
Sbjct: 2467 GPYKLIV 2473



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
             I+ G  L L+  + G P P+V+W K ++   +    ++     +     I   +  D G 
Sbjct: 10858 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK---LEIRNAAHEDGGI 10914

Query: 1644  YGLVVKNKYGSETSDFTVSV 1663
             Y L V+N  GS+T    V V
Sbjct: 10915 YSLTVENPAGSKTVSVKVLV 10934



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 13/87 (14%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG--RTAYFT---INGV 1636
             + ++ G ++ +   + G P PEV+W K        D+ NLK  A    T  FT   I   
Sbjct: 14414 LVVRAGLSIRIFVPIKGRPAPEVTWTK--------DNINLKNRANIENTESFTLLIIPEC 14465

Query: 1637  STADSGKYGLVVKNKYGSETSDFTVSV 1663
             +  D+GK+ + ++N  G ++    V V
Sbjct: 14466 NRYDTGKFVMTIENPAGKKSGFVNVRV 14492



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 38/176 (21%), Positives = 75/176 (42%), Gaps = 16/176 (9%)

Query: 1165 PKSEFSWSKD--YVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSY 1222
            P  E SW +D   +ST   P +++     + K+T   +   + G YS   T+  G A+S 
Sbjct: 33   PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATS- 91

Query: 1223 LIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEK 1282
                 EL     L      P   V+   ++ + +  QVR  ++   +     V +  +  
Sbjct: 92   ---TAEL-----LVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIP-TPVVKFYRDGA 142

Query: 1283 EIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD--GKATNHSTVVLVGD 1336
            EI     ++  I +   +  + + +   ED GTY+    +  G+AT+ + +++ G+
Sbjct: 143  EIQSSLDFQ--ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 43/204 (21%), Positives = 67/204 (32%), Gaps = 47/204 (23%)

Query: 278  EFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTL 337
            + I KP+  T  E   V    S++    P V W+   V I       K+ + S   +H L
Sbjct: 2750 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPS---DKHRLVSERKVHKL 2805

Query: 338  EINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPY 397
             +      D  +Y A    V G+L   A + V+                           
Sbjct: 2806 MLQNISPSDAGEYTA----VVGQLECKAKLFVET-------------------------- 2835

Query: 398  GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQ 457
                   +H           E +T S  C      E+ HF     W +NGV +  S+  +
Sbjct: 2836 -------LHITKTMKNIEVPETKTASFEC------EVSHFNVPSMWLKNGVEIEMSEKFK 2882

Query: 458  TLWSGERATLTFSHLNKEDEGLYT 481
             +  G+   L   + + ED   YT
Sbjct: 2883 IVVQGKLHQLIIMNTSTEDSAEYT 2906



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
             ++ G +  +T    G P P V W K +  L +  + +      RT+  TI   +  DSGK
Sbjct: 19826 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDT--TDSRTS-LTIENANRNDSGK 19882

Query: 1644  YGLVVKNKYGSETSDFTVSV 1663
             Y L ++N   + +    V V
Sbjct: 19883 YTLTIQNVLSAASLTLVVKV 19902



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 5/45 (11%)

Query: 418  EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG 462
            EGET    CRV   P     QP++ WY NG  +  SK  +  + G
Sbjct: 1808 EGETARFRCRVTGYP-----QPKVNWYLNGQLIRKSKRFRVRYDG 1847



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 17/89 (19%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALA-------SDDHCNLKFEAGRTAYFTIN 1634
             + +++G  + LT  + G P P   W K  + ++       S+ H  L           I 
Sbjct: 23774 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTEL----------VIK 23823

Query: 1635  GVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
                  DSG Y LV++NK G +     V V
Sbjct: 23824 EADRGDSGTYDLVLENKCGKKAVYIKVRV 23852



 Score = 31.6 bits (70), Expect = 6.8
 Identities = 44/203 (21%), Positives = 71/203 (34%), Gaps = 46/203 (22%)

Query: 278  EFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTL 337
            +F+      TV E E     C ++   +  V W+KN   ++        +I S    H L
Sbjct: 5203 KFMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRT---VLISSEGKTHKL 5258

Query: 338  EINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPY 397
            E+     +D +Q +A       ELS+ A + V                          PY
Sbjct: 5259 EMKEVTLDDISQIKAQVK----ELSSTAQLKVLE----------------------ADPY 5292

Query: 398  GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQ 457
                 F +   DK  V    E + ++L C V     +K       W+++G  + PS    
Sbjct: 5293 -----FTVKLHDKTAV----EKDEITLKCEVSKDVPVK-------WFKDGEEIVPSPKYS 5336

Query: 458  TLWSGERATLTFSHLNKEDEGLY 480
                G R  L     + +D+G Y
Sbjct: 5337 IKADGLRRILKIKKADLKDKGEY 5359



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 8/88 (9%)

Query: 1598 GDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTIN-GVS-TADSGKYGLVVKNKYGSE 1655
            GDP   V WL + K L + +   +  E G   Y +++ GV+ + DSG       NKYG  
Sbjct: 1684 GDPTMVVEWLHDGKPLEAANRLRMINEFG---YCSLDYGVAYSRDSGIITCRATNKYG-- 1738

Query: 1656 TSDFTVSVFIPEEEARMAALESLKGGKK 1683
             +D T +  I ++E  +     L  G+K
Sbjct: 1739 -TDHTSATLIVKDEKSLVEESQLPEGRK 1765



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 6/60 (10%)

Query: 419  GETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEG 478
            GET +  C      E+ +    ++WY  G  L PS  V     G+  TLT   +  ED G
Sbjct: 5838 GETATFDC------ELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAG 5891



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 1598 GDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETS 1657
            G P P  +W   +K L + D   +K      A   I+    +D G Y L ++N+  + + 
Sbjct: 7048 GYPRPTATWCFGDKVLETGDRVKMK-TLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7106

Query: 1658 DFTVSVFIPEEEARMAALESLKGGKKAK 1685
            +  V+V      AR +A + LK G   K
Sbjct: 7107 EIDVNVI-----ARPSAPKELKFGDITK 7129



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 7/91 (7%)

Query: 1592  LTCNVWGDPPPEVSWLKNEKALASDDHCNLKFE----AGRTAYFTINGVSTADSGKYGLV 1647
             L C V G P P V W +  K + +D    LK+      G      I  V+  D+  Y + 
Sbjct: 24575 LVCKVTGHPKPIVKWYRQGKEIIAD---GLKYRIQEFKGGYHQLIIASVTDDDATVYQVR 24631

Query: 1648  VKNKYGSETSDFTVSVFIPEEEARMAALESL 1678
               N+ GS +   ++ V +P +      LE +
Sbjct: 24632 ATNQGGSVSGTASLEVEVPAKIHLPKTLEGM 24662


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score =  257 bits (656), Expect = 8e-68
 Identities = 233/902 (25%), Positives = 381/902 (42%), Gaps = 102/902 (11%)

Query: 405   IHFDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGE 463
             +  D KF DV   + GE + +   +   P      P I W ++G+ +      + + +  
Sbjct: 19292 VMMDVKFRDVIVVKAGEVLKINADIAGRP-----LPVISWAKDGIEIEERARTEIISTDN 19346

Query: 464   RATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANK 523
                LT     + D G Y + ++        +    V D      G PA PL++  L A K
Sbjct: 19347 HTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKP----GPPAGPLEINGLTAEK 19402

Query: 524   DYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFR 583
                 +SW +P  DGG+ I  Y ++K E    +W+ C +  ++     VT L++G  YIFR
Sbjct: 19403 --CSLSWGRPQEDGGADIDYYIVEKRETSHLAWTIC-EGELQMTSCKVTKLLKGNEYIFR 19459

Query: 584   VRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTD 643
             V  VNK G+G P   S  + ALDP                             VP PPT 
Sbjct: 19460 VTGVNKYGVGEPLE-SVAIKALDPFT---------------------------VPSPPTS 19491

Query: 644   LSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDL 702
             L +T  T+  + L W +P    G E   Y +E+ E  +  W RVN + PV   R     L
Sbjct: 19492 LEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKK-PVYDLRVKSTGL 19550

Query: 703   AEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES 762
              EG  Y +RV   N+AG+  PSE + +    D + +P  P K     +  T++ ++W + 
Sbjct: 19551 REGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKP 19610

Query: 763   --KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLS 820
                    + GY +E   +    W+    + ++G+ +T  GL TG  Y+FRV++VN  G S
Sbjct: 19611 LFDGGAPITGYTVEYKKSDDTDWKTSIQS-LRGTEYTISGLTTGAEYVFRVKSVNKVGAS 19669

Query: 821   EYSQDSE---AIEVKAAIGGGVSPDVCPALSDEPGG----LTASRGR----VHEASPPT- 868
             + S  S+   A E +      +  ++   L  + G         RGR    V  + P T 
Sbjct: 19670 DPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTD 19729

Query: 869   FQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKK 928
              +  A + +  ++ SL  + +N  + +  K + T+Q  L+           +    + K 
Sbjct: 19730 LRTRAYVDTTDSRTSL--TIENANRNDSGKYTLTIQNVLS----------AASLTLVVKV 19777

Query: 929   TDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
              D   P PP +IT  +  ++S VL W  P+  GGA +  Y++  RE       K   +  
Sbjct: 19778 LD--TPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKRE----ASKKAWVSVT 19831

Query: 989   KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCS 1048
                +  +YK++NL+E  +Y F+V+  N  G+G P+   E  K  E     P PP  L  +
Sbjct: 19832 NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITE----KPSPPEKLGVT 19887

Query: 1049  EVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEG 1108
              + KDS+ L W  P H G + +  Y V+  E   K   W  +  A  K+ +  V GL+E 
Sbjct: 19888 SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK--NW--VKCAVAKSTHHVVSGLREN 19943

Query: 1109  VSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISL----NFECD--- 1161
               Y FRV A NQAG+  P +L  PV+ + +    E+ +       + +    N + D   
Sbjct: 19944 SEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPI 20003

Query: 1162  KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
                P  + + S+D V  + + R   E       +  K+    D G Y     ++ G   +
Sbjct: 20004 SGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKA 20063

Query: 1222  YLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNE 1281
             ++        ++ L      P  P    +  +I E+     W   +   G+   NYI  +
Sbjct: 20064 FI-------NIVVLDR----PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLK 20112

Query: 1282  KE 1283
             +E
Sbjct: 20113 RE 20114



 Score =  248 bits (632), Expect = 5e-65
 Identities = 214/828 (25%), Positives = 356/828 (42%), Gaps = 107/828 (12%)

Query: 429  VITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGE 488
            ++ P   + + E +W++   PLS +K + T  + E+ +       K D+G Y I ++   
Sbjct: 6522 MVVPYDAYPKAEAEWFKENEPLS-TKTIDT--TAEQTSFRILEAKKGDKGRYKIVLQ--N 6576

Query: 489  YYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDK 548
             + +   ++ ++  D      P    +++  E     + ++W++P  DGGS I+GY +++
Sbjct: 6577 KHGKAEGFINLKVIDV-----PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVER 6631

Query: 549  CEVGTDSWSQCNDTPVKFARFPVTGLIEGR-SYIFRVRAVNKMGIGFPSRVSEPVAALDP 607
             ++   +W    D   +   F VTGL +G   Y+FRV A N++G G P     PV     
Sbjct: 6632 RDIKRKTWVLATDR-AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPV----- 6685

Query: 608  AEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHE 667
                                  E  S+  VPGPP ++++T+  R  V L+W+PP   G  
Sbjct: 6686 ----------------------EARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGA 6723

Query: 668  GIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEA 726
             I  Y +E  +  +  W    T +  +     + D+ EG+ Y FRVR  N  GVG+PS A
Sbjct: 6724 EITNYVIELRDKTSIRWDTAMT-VRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAA 6782

Query: 727  TEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-KD-AKELVGYYIEASVAGSGKWE 784
            T    V D ++ P  P  +  S  T +SV + WE   KD    ++GY IE    G   W 
Sbjct: 6783 TPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWI 6842

Query: 785  PCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVC 844
             CN   V    +   GL  G  Y++RV A N AG+S+ S+                    
Sbjct: 6843 RCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEIL------------------ 6884

Query: 845  PALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVS-----KV 899
                   G LTA    V      +  KD L    PN  ++   S    +   +     KV
Sbjct: 6885 -------GPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 6937

Query: 900  SET----------VQEELTPPPQKAAPQG------KSKSDPLKKKTD---RAPPSPPCDI 940
             ET             EL   P + + +G      +++   +  + D    A PS P ++
Sbjct: 6938 LETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKEL 6997

Query: 941  TCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISN 1000
               +  +DS+ L W+ PD  GG+ +TGY V  REV       W +  +  V++  + + +
Sbjct: 6998 KFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKT---WTKV-MDFVTDLEFTVPD 7053

Query: 1001 LKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWK 1060
            L +   Y F+V A N  G G P+ V E          VP PP ++K  +   +S+ L W 
Sbjct: 7054 LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMST-PATVPDPPENVKWRDRTANSIFLTWD 7112

Query: 1061 PPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQ 1120
            PP + G + + GY V+        D+W    E  +    ++V GL+EG  Y +RV+A+N+
Sbjct: 7113 PPKNDGGSRIKGYIVE--RCPRGSDKWVACGE-PVAETKMEVTGLEEGKWYAYRVKALNR 7169

Query: 1121 AGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISL----NFECDKMT---PKSEFSWSK 1173
             G  KPS     + A       E+ ++V     +++      E        P+ + +W+K
Sbjct: 7170 QGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTK 7229

Query: 1174 DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
              +  +   R+ +E+   K+ +T  D    D G Y  +  +  G A++
Sbjct: 7230 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATA 7277



 Score =  247 bits (631), Expect = 6e-65
 Identities = 233/877 (26%), Positives = 353/877 (40%), Gaps = 116/877 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P + W ++G  L P++ ++        TL    +N++D G YTI        +  +  + 
Sbjct: 12828 PTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLK 12887

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V D        P  P  VK  +   D  ++SW+ P  DGGS I  Y +DK E    +W+Q
Sbjct: 12888 VLDK-------PGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQ 12940

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              + T V      V  LIEG  Y FR+ A NK G+G P   +EP  A +P +         
Sbjct: 12941 VSAT-VPITSCSVEKLIEGHEYQFRICAENKYGVGDPV-FTEPAIAKNPYDP-------- 12990

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                                PG      ++  T+ ++ +SWKPP   G   I  Y +EK E
Sbjct: 12991 -------------------PGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRE 13031

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
                 NW +VN + P+         L EG  Y FRV   N AG G+PS+A++     D   
Sbjct: 13032 TQAVNWTKVNRK-PIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQY 13090

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCN-NNPVKGS 794
              P  P        T +SV +SW +        ++GY +E   A S  W  CN    ++ +
Sbjct: 13091 PPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13150

Query: 795   RFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAI---GGGVSPDVCPALSDEP 851
             RF   GL+    Y FRV AVN  G S+ S   +    K  +    G +  D+   L    
Sbjct: 13151 RFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRA 13210

Query: 852   GGLTASRGRVHEASPPTFQKDALLGSKPN-----KPSLPSSS---------QNLGQTEVS 897
             G        V    PP      +  SKPN     +  L   S         +N+ + +  
Sbjct: 13211 GVTMRLYVPVKGRPPP-----KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13265

Query: 898   KVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQP 957
             K   T++             GK +   + K  D   P PP ++T  E  +DS  + W+ P
Sbjct: 13266 KYILTLENSC----------GKKEYTIVVKVLD--TPGPPVNVTVKEISKDSAYVTWEPP 13313

Query: 958   DKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMA 1017
                GG+ I  Y V  R   D     W     +  S+ +++++NL+E   Y F+V A N  
Sbjct: 13314 IIDGGSPIINYVVQKR---DAERKSWSTVTTEC-SKTSFRVANLEEGKSYFFRVFAENEY 13369

Query: 1018  GLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDL 1077
             G+G P    +  K  +     PGP   LK   V K S  + WK P   G + + GY VD 
Sbjct: 13370 GIGDPGETRDAVKASQ----TPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 13425

Query: 1078  KEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET 1137
                  +E++W+ + ++   ++    + L EG  Y FRV A N+ G G PS++   VVA  
Sbjct: 13426 ---LTEENKWQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVAR- 13477

Query: 1138  RPGTKEVVVNVDDDGVISL--------NFECD---KMTPKSEFSWSKDYVSTEDSPRLEV 1186
                   V  ++D  G+  L        NF      K  P    SW K         R+ V
Sbjct: 13478 ---DDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13534

Query: 1187  ESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPV 1246
             ES    T +   D    D G Y+  + +  G     +         + +  +   PT P+
Sbjct: 13535 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTI--------SIKVVGKPGIPTGPI 13586

Query: 1247  KSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
             K +   E+  +     W   +   G+   NYI  +++
Sbjct: 13587 KFD---EVTAEAMTLKWAPPKDDGGSEITNYILEKRD 13620



 Score =  247 bits (630), Expect = 8e-65
 Identities = 216/807 (26%), Positives = 347/807 (42%), Gaps = 78/807 (9%)

Query: 438  QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
            +P+I W +  + L   K +      +++T+T     + D G Y I         + +A V
Sbjct: 7222 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAV--NVCGRATAVV 7279

Query: 498  FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
             V   D      P  P      +   +  +++W  P  DGGS I  Y +++    ++ W 
Sbjct: 7280 EVNVLDK-----PGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWH 7334

Query: 558  QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAA---LDPAEKARLK 614
            + + T VK   F  T LI  + YIFRV A N  G+G P + S P+ A    DP       
Sbjct: 7335 KLSST-VKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQAS-PITAKYQFDP------- 7385

Query: 615  SRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFV 673
                                   PGPPT L  ++ T+  V L+W  P   G   I  Y+V
Sbjct: 7386 -----------------------PGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWV 7422

Query: 674  EKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVG 733
            E+ +  T+ W R N ++PVK   + +  L   K Y FRV   N AG G+PS++TE  ++ 
Sbjct: 7423 ERLDPDTDKWVRCN-KMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIK 7481

Query: 734  DKLDIPKAPGKIIPSRNTDTSVVVSW--EESKDAKELVGYYIEASVAGSGKWEPCNNNPV 791
            D +D P  PGK        TSV ++W   E     ++  Y IE    G+ +W       V
Sbjct: 7482 DPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEG-V 7540

Query: 792  KGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEP 851
              ++    GL+ GQ Y FRVRAVN AG SE S+ S+ +  +  +     P     ++   
Sbjct: 7541 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVIN--- 7597

Query: 852  GGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETV---QEELT 908
              +T +   +    P       +      K  +         T V     TV    E   
Sbjct: 7598 --ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSL 7655

Query: 909  PPPQKAAPQGKSKS------DPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGG 962
               + AA     +S      D +  K     P PP  +  ++  +  + L W+ P   GG
Sbjct: 7656 YVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGG 7715

Query: 963  AEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
              I  Y +  +E +     +W +A   A  +  ++++++ E    QFQV A N AG+G P
Sbjct: 7716 RPIQRYVIEKKERLG---TRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHP 7772

Query: 1023 SAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKA 1082
            S  +E    E+ T + P PP  L  ++  +  + + WKPP  +G +P+ GY V++     
Sbjct: 7773 SEPTEILSIEDPT-SPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEM--CPV 7829

Query: 1083 KEDQWRGLNEAAIKNVYLKV-RGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA---ETR 1138
              ++W  +N   IK++  KV  G+     YV RVRA+N  GV +PS+++  VVA   + +
Sbjct: 7830 GTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCK 7889

Query: 1139 P----GTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTK 1194
            P     T +++V   +   I + F   +  P    SW KD    + S RL +++      
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPF---RAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 7946

Query: 1195 MTFKDLGMDDLGIYSCDVTDTDGIASS 1221
            +        D GIY+  + +  G A++
Sbjct: 7947 LEVPKSVRADAGIYTITLENKLGSATA 7973



 Score =  244 bits (623), Expect = 5e-64
 Identities = 210/715 (29%), Positives = 320/715 (44%), Gaps = 77/715 (10%)

Query: 432   PEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHL---NKEDEGLYTIRVR--M 486
             P I   +P I W ++G PL  +  V      E AT T  H+   NK+D G YT+      
Sbjct: 17837 PVIGRPRPNISWVKDGEPLKQTTRVNV---EETATSTVLHIKEGNKDDFGKYTVTATNSA 17893

Query: 487   GEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFI 546
             G   E  S  V       E  G P  P  V+  E + D+++ISW+ PA  GG  I  Y +
Sbjct: 17894 GTATENLSVIVL------EKPGPPVGP--VRFDEVSADFVVISWEPPAYTGGCQISNYIV 17945

Query: 547   DKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALD 606
             +K +  T +W   + T  +     +T L  G  Y FR+ A N+ G               
Sbjct: 17946 EKRDTTTTTWHMVSATVAR-TTIKITKLKTGTEYQFRIFAENRYG--------------- 17989

Query: 607   PAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGH 666
                        SAP   + ++ +    E   PGPP    VT  ++  +++ W  P   G 
Sbjct: 17990 ----------KSAPLDSKAVIVQYPFKE---PGPPGTPFVTSISKDQMLVQWHEPVNDGG 18036

Query: 667   EGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSE 725
               I+ Y +E+ E  +  W ++N + P++  +F    L EG  Y F+V   N  G+G+PS+
Sbjct: 18037 TKIIGYHLEQKEKNSILWVKLN-KTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSK 18095

Query: 726   ATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKW 783
              +E  V  D  D P  P  I+ +RN   +V + W++       ++ GY +E      G+W
Sbjct: 18096 VSECFVARDPCDPPGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW 18152

Query: 784   EPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAI---GGGV 839
                +   V  + FT  GLV  Q Y FRV A NAAG  SE S  S AI  +  I      +
Sbjct: 18153 MKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASL 18212

Query: 840   SP---DVCPALSDEPGGLTAS-RGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTE 895
              P   DV    + E   L A  RG+        + KD   G +  + +     ++  Q  
Sbjct: 18213 DPKYKDVIVVHAGETFVLEADIRGK--PIPDVVWSKD---GKELEETAARMEIKSTIQKT 18267

Query: 896   VSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKT-DR-APPSPPCDITCLESFRDSMVLG 953
                V + ++ +      K +  G +KS P+  K  DR  PP  P  +T + +  +   L 
Sbjct: 18268 TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTA--EKCYLA 18325

Query: 954   WKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAA 1013
             W  P + GGA I+ Y +  RE        W + + + V    YK++ L     Y F+V A
Sbjct: 18326 WNPPLQDGGANISHYIIEKRET---SRLSWTQVSTE-VQALNYKVTKLLPGNEYIFRVMA 18381

Query: 1014  MNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGY 1073
             +N  G+G P        C  +    PGPP + + S + KDS+V+ W  PV  G T + GY
Sbjct: 18382 VNKYGIGEPLESGPVTACNPY--KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY 18439

Query: 1074  FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              ++ ++ +    +W   N+  + ++ L+V GL EG SY FRV A N AGVG+PS+
Sbjct: 18440 ILEKRDKEGV--RWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSE 18492



 Score =  240 bits (612), Expect = 1e-62
 Identities = 232/891 (26%), Positives = 374/891 (41%), Gaps = 101/891 (11%)

Query: 417   REGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             R G  + L   V   PE     P+I W +    L   + V   ++G+RAT      ++ D
Sbjct: 22563 RAGSDLVLDAAVGGKPE-----PKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSD 22617

Query: 477   EGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVD 536
              G YT+ V+     +  S  V V D+       P   L V  +   K    ++W  P  D
Sbjct: 22618 SGKYTLTVKNASGTKAVSVMVKVLDSPG-----PCGKLTVSRVTQEK--CTLAWSLPQED 22670

Query: 537   GGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPS 596
             GG+ I  Y +++ E    +W          + + VT LI+   YIFRVRAVNK G G P 
Sbjct: 22671 GGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYGPGVPV 22729

Query: 597   RVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVL 656
               SEP+ A +                              +P PP         + ++++
Sbjct: 22730 E-SEPIVARNSFT---------------------------IPSPPGIPEEVGTGKEHIII 22761

Query: 657   SW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCS 715
              W KP    G+E   Y V+K E  +  W RVN +  V   R  +  L EG  Y FRV   
Sbjct: 22762 QWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAV 22821

Query: 716   NSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYI 773
             N+AG  EPSEA+      +    P  P        T  S+ ++W +       ++VGY +
Sbjct: 22822 NAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVL 22881

Query: 774   EASVAGSGKWEPCNNN-PVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVK 832
             E     + +W   + N  ++ + FT   L  GQ Y FRV AVN  G+SEYS+    IE  
Sbjct: 22882 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 22941

Query: 833   AAI---GGGVSPDVCPALSDEPGGLTASRGRVHEASPP--TFQKDAL-LGSKPNKPSLPS 886
               I      ++ D+   ++   G        V    PP  T+ K  + L S+    ++  
Sbjct: 22942 ERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASR----AIID 22997

Query: 887   SSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESF 946
             ++++     V KV+     + T   +  +  GK  +  L K  D   P P   +   E  
Sbjct: 22998 TTESYSLLIVDKVNRYDAGKYTIEAENQS--GKKSATVLVKVYDTPGPCP--SVKVKEVS 23053

Query: 947   RDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMV 1006
             RDS+ + W+ P   GGA +  Y V  RE        ++    K  S+  Y+IS L E  +
Sbjct: 23054 RDSVTITWEIPTIDGGAPVNNYIVEKRE---AAMRAFKTVTTKC-SKTLYRISGLVEGTM 23109

Query: 1007  YQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSG 1066
             Y F+V   N+ G+G P   S+     E    VP  P  L+  +V K ++ L W+ P++ G
Sbjct: 23110 YYFRVLPENIYGIGEPCETSDAVLVSE----VPLVPAKLEVVDVTKSTVTLAWEKPLYDG 23165

Query: 1067  RTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLK--VRGLKEGVSYVFRVRAINQAGVG 1124
              + +TGY   L+  KA  ++W  +    +K   L+  V  L EG  Y+FR+RA N+ GV 
Sbjct: 23166 GSRLTGYV--LEACKAGTERW--MKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVS 23221

Query: 1125  KPSDLAGPVVAE-----------TRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSK 1173
             +P +    V  +           T P   +  ++V     + L        P +  SW  
Sbjct: 23222 EPRETVTAVTVQDLRVLPTIDLSTMP---QKTIHVPAGRPVELVIPIAGRPPPAA-SWFF 23277

Query: 1174  DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLL 1233
                   +S R+ VE+     K+T ++  + D G Y+ ++ +  G  S       E  +++
Sbjct: 23278 AGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTS-------ETIKVI 23330

Query: 1234  ALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVN-YIFNEKE 1283
              L      PT P+K    ++ ++   +    +  +L G A ++ Y+  +++
Sbjct: 23331 ILDKPGP-PTGPIK----IDEIDATSITISWEPPELDGGAPLSGYVVEQRD 23376



 Score =  239 bits (609), Expect = 2e-62
 Identities = 243/973 (24%), Positives = 389/973 (39%), Gaps = 133/973 (13%)

Query: 339   INGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYG 398
             + G    DT +YR SA+N+ G+            K E      H                
Sbjct: 10281 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLH---------------- 10324

Query: 399   YASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQT 458
                   + F DK  +   R GE  +L  R    P+     P++ W+++   +        
Sbjct: 10325 ------LDFRDKLTI---RVGEAFALTGRYSGKPK-----PKVSWFKDEADVLEDDRTHI 10370

Query: 459   LWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKC 518
               +     L      + D G Y + V       +    V V D      G P  P+    
Sbjct: 10371 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRP----GPPVGPVSFD- 10425

Query: 519   LEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGR 578
              E  KDY++ISWK P  DGGS I  Y I+K EVG D W        K     V+ L+EG+
Sbjct: 10426 -EVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAK-TTCKVSKLLEGK 10483

Query: 579   SYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVP 638
              YIFR+ A N  GI      S+P+ +     K R +                      VP
Sbjct: 10484 DYIFRIHAENLYGI------SDPLVSDSMKAKDRFR----------------------VP 10515

Query: 639   GPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFA 698
               P    VTE T+   +++W  P   G     Y +EK E  ++ W RV  +      +F 
Sbjct: 10516 DAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFR 10575

Query: 699   LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVS 758
             + DL EG  Y FRV   N  G+G+PS  ++     D +  P  P        T  SV ++
Sbjct: 10576 VPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLT 10635

Query: 759   WEESK--DAKELVGYYIEASVAGSGKWEPCNNNP--VKGSRFTCHGLVTGQSYIFRVRAV 814
             W+  +     +++GY +E    G  +W   N+ P     +++   GL  GQ+Y FRV AV
Sbjct: 10636 WQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAV 10695

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGR-VHEASPPTFQKDA 873
             NAAG S+ +   E + VK  +     P++          L A+  R  H     T +  A
Sbjct: 10696 NAAGESDPAHVPEPVLVKDRL---EPPELI---------LDANMAREQHIKVGDTLRLSA 10743

Query: 874   LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSD---------- 923
             ++   P  P +    ++      +++      ++TP   K   +  +  D          
Sbjct: 10744 IIKGVP-FPKVTWKKEDRDAPTKARI------DVTPVGSKLEIRNAAHEDGGIYSLTVEN 10796

Query: 924   PLKKKTDRA------PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVID 977
             P   KT          P PP D+   E  +DS  L WK+P   GG+ IT Y V  R+V  
Sbjct: 10797 PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDV-- 10854

Query: 978   GVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIA 1037
                 +W   +  +  ++++   +L E   Y F+VAA N  G G      +  K  +  + 
Sbjct: 10855 -ASAQWSPLSATS-KKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD-PLH 10911

Query: 1038  VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
              PGPP  L   +V K  + L W  P   G +P+TGY V+ +E   ++  W  +    + N
Sbjct: 10912 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQD--W--IKFKTVTN 10967

Query: 1098  VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR--PGTKEVVVNVDDDGVI- 1154
             +   V GL++G +Y FRV+A N  G+G P D   P+  + +  P + E+ V + +  V+ 
Sbjct: 10968 LECVVTGLQQGKTYRFRVKAENIVGLGLP-DTTIPIECQEKLVPPSVELDVKLIEGLVVK 11026

Query: 1155  ---SLNFEC-DKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSC 1210
                ++ F    +  P     W+ D    +      VE+    + +T K+    D G Y  
Sbjct: 11027 AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11086

Query: 1211  DVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLS 1270
              V++  G         + +   L +      PT P+     +++  +     W   +   
Sbjct: 11087 TVSNAAG--------SKTVAVHLTVLDVPGPPTGPIN---ILDVTPEHMTISWQPPKDDG 11135

Query: 1271  GNAKVNYIFNEKE 1283
             G+  +NYI  +++
Sbjct: 11136 GSPVINYIVEKQD 11148



 Score =  238 bits (606), Expect = 5e-62
 Identities = 256/1027 (24%), Positives = 414/1027 (40%), Gaps = 150/1027 (14%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             +N+K+   + G P+P VTW K      +     +   E+      L IN C   D+  Y 
Sbjct: 14584 DNIKVEIPVLGRPKPTVTWKKGD---QILKQTQRVNFETTATSTILNINECVRSDSGPYP 14640

Query: 352   ASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKF 411
              +A N+ GE+    ++ V    G            T P+ F      +            
Sbjct: 14641 LTARNIVGEVGDVITIQVHDIPGP----------PTGPIKFDEVSSDF------------ 14678

Query: 412   DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH 471
              V+F  +      G        I ++  E++          + WV+   +  R T   + 
Sbjct: 14679 -VTFSWDPPENDGGV------PISNYVVEMR------QTDSTTWVELATTVIRTTYKATR 14725

Query: 472   LNKEDEGLYTIRVRMGEYY---EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIII 528
             L    E  Y  RV+    Y      ++   V +   ++ G P  P   +     KD + I
Sbjct: 14726 LTTGLE--YQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTP---QVTAVTKDSMTI 14780

Query: 529   SWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVN 588
             SW +P  DGGSPILGY +++ E     W   +   V    F  +GL +G +Y FRV A N
Sbjct: 14781 SWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAEN 14840

Query: 589   KMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTE 648
               G   PS+ SEP+ ALDP +                            PG P  L++T 
Sbjct: 14841 MAGKSKPSKPSEPMLALDPIDP---------------------------PGKPVPLNITR 14873

Query: 649   ATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKS 707
              T   V L W KP    G +   Y VEK +     W + N    +++  F +  L E  +
Sbjct: 14874 HT---VTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILEN-EFTVSGLTEDAA 14929

Query: 708   YCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAK 766
             Y FRV   N+AG +  PSE ++     D ++ PK              V V ++++   K
Sbjct: 14930 YEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKI------------KVDVKFKDTVILK 14977

Query: 767   ELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDS 826
                 + +EA V  SG+  P       G        +  +   F    VN        +DS
Sbjct: 14978 AGEAFRLEADV--SGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNK---DSTRRDS 15032

Query: 827   EAIEVKAAIGGGVSPDVC-------PALSDEPGGLT--ASRGRVHEASPPTFQKDALLG- 876
              A  + A   GG +  +        P   + P  +T   S   V    PP     A +  
Sbjct: 15033 GAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDH 15092

Query: 877   --------SKPNKPSLPSSSQ--NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLK 926
                     S+    ++ S  Q   L  T++ K +E +   +     K       +S+P+ 
Sbjct: 15093 YIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV--NKYGVGEPLESEPVL 15150

Query: 927   KKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREA 986
                   PP PP +       +DSMV+ W  PD  GG+EI  Y V  R   D    +W + 
Sbjct: 15151 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERR---DKAGQRWIKC 15207

Query: 987   NVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK-CEEWTIAVPGPPHSL 1045
             N K +++  YK+S L E   Y+F++ A N AG+ APS  S  +K C+  T+  PGPP + 
Sbjct: 15208 NKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD--TVFKPGPPGNP 15265

Query: 1046  KCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRG 1104
             +  +  + S+ + W  P++ G + +TGY V++  A  +ED+W+ +   A +K     + G
Sbjct: 15266 RVLDTSRSSISIAWNKPIYDGGSEITGYMVEI--ALPEEDEWQIVTPPAGLKATSYTITG 15323

Query: 1105  LKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECD--- 1161
             L E   Y  R+ A+N  G+G+P+ + G   AE R    E+ ++ D   V+++   C    
Sbjct: 15324 LTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRL 15383

Query: 1162  ----KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
                 K  P  E  W++D+  + D  +  +ES  + T +   ++   D G Y   V ++ G
Sbjct: 15384 FVPIKGRPAPEVKWARDHGESLD--KASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG 15441

Query: 1218  IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV-N 1276
               S+++             +     T     +L V+ + K  V        L G +K+ N
Sbjct: 15442 SKSAFV-------------NVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15488

Query: 1277  YIFNEKE 1283
             YI  ++E
Sbjct: 15489 YIVEKRE 15495



 Score =  236 bits (602), Expect = 1e-61
 Identities = 213/769 (27%), Positives = 319/769 (41%), Gaps = 97/769 (12%)

Query: 398   GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPE-----------IQWYRN 446
             G   +F +   +   VS  RE E +      ++ P+I    PE           I+ +  
Sbjct: 12369 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI--LMPEQITIKAGKKLRIEAHVY 12426

Query: 447   GVPLSPSKWVQTLWSGERATLTFSHL----------------NKEDEGLYTIRVRMGEYY 490
             G P    KW +    GE   +T SHL                 ++D G Y++        
Sbjct: 12427 GKPHPTCKWKK----GEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGT 12482

Query: 491   EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCE 550
             +     V V DA     G P  P D+  ++A  D   +SW  P  DGGS I  Y ++KC+
Sbjct: 12483 DTQKIKVVVMDAP----GPPQPPFDISDIDA--DACSLSWHIPLEDGGSNITNYIVEKCD 12536

Query: 551   VGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEK 610
             V    W     +  K +   V  LI G+ YIFRVRA N+ GI  P    + VA       
Sbjct: 12537 VSRGDWVTALASVTKTS-CRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG-- 12593

Query: 611   ARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM 670
                                       VP  P +  VT+  +  + ++W  P   G   I+
Sbjct: 12594 --------------------------VPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPII 12627

Query: 671   -YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEV 729
              Y +E+ E  +  W + N  L V+S  +    L EG  Y FR+   N AG   PS+ TE 
Sbjct: 12628 GYLIERKERNSLLWVKANDTL-VRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEY 12686

Query: 730   TVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNN 789
                   +D P  P  I  +++T  S++ +  +     +++GY++EA      KW  CN  
Sbjct: 12687 VTARMPVDPPGKPEVIDVTKST-VSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTA 12745

Query: 790   P--VKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSP--DVCP 845
             P  +    +T  GL     Y FR  A  A  +S  S+ S+ + + A     V P  D+  
Sbjct: 12746 PHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAE---NVPPRIDLSV 12802

Query: 846   ALSD----EPGGLTASRGRVHEASPPT--FQKDALLGSKPNKPSLPSSSQNLGQTEVSKV 899
             A+      + G        V     PT  ++KD  L  KP +    +  +NL   E+  V
Sbjct: 12803 AMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL-LKPAEGIKMAMQRNLCTLELFSV 12861

Query: 900   SETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDK 959
             +     + T   + ++    SKS  +K K     P PP  +   + + D  +L W+ P +
Sbjct: 12862 NRKDSGDYTITAENSSG---SKSATIKLKV-LDKPGPPASVKINKMYSDRAMLSWEPPLE 12917

Query: 960   IGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GG+EIT Y V+ RE        W + +   V   +  +  L E   YQF++ A N  G+
Sbjct: 12918 DGGSEITNYIVDKRETSRP---NWAQVSA-TVPITSCSVEKLIEGHEYQFRICAENKYGV 12973

Query: 1020  GAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
             G P           +    PG       S + KD + + WKPP   G +P+TGY ++ +E
Sbjct: 12974 GDPVFTEPAIAKNPYD--PPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRE 13031

Query: 1080  AKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              +A    W  +N   I    LK  GL+EG  Y FRV AIN+AG GKPSD
Sbjct: 13032 TQAVN--WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 13078



 Score =  235 bits (600), Expect = 2e-61
 Identities = 248/1071 (23%), Positives = 420/1071 (39%), Gaps = 153/1071 (14%)

Query: 294   VKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRAS 353
             V+L   IAG P P  +W+     +       +  +E+   +  L I      DT +Y   
Sbjct: 23259 VELVIPIAGRPPPAASWFFAGSKLR---ESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23315

Query: 354   AMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDV 413
               NV G  S    V++    G                     P G     EI   D   +
Sbjct: 23316 LKNVTGTTSETIKVIILDKPGP--------------------PTGPIKIDEI---DATSI 23352

Query: 414   SFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLN 473
             +   E   +  G      P   +   +   +R G       W+    S  R+T  F+ L 
Sbjct: 23353 TISWEPPELDGGA-----PLSGYVVEQRDAHRPG-------WLPVSESVTRSTFKFTRLT 23400

Query: 474   KEDEGLYTI----RVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIIS 529
             + +E ++ +    R  +G Y +       V +  + I   P  P  ++  + ++D + ++
Sbjct: 23401 EGNEYVFRVAATNRFGIGSYLQSE-----VIECRSSIR-IPGPPETLQIFDVSRDGMTLT 23454

Query: 530   WKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNK 589
             W  P  DGGS + GY +++ EV  D W + N  PV   R+  TGL EG  Y  RV A+N 
Sbjct: 23455 WYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINA 23514

Query: 590   MGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEA 649
              G G PSR S+P+ A+DP           AP                 PG P +  VT+ 
Sbjct: 23515 RGSGKPSRPSKPIVAMDPI----------AP-----------------PGKPQNPRVTDT 23547

Query: 650   TRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSY 708
             TR+ V L+W  P   G   +  Y +E  +     W + NT  P K   + L  L +G  Y
Sbjct: 23548 TRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTT-PTKIREYTLTHLPQGAEY 23606

Query: 709   CFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKEL 768
              FRV   N+ G GEP+E      V + L+ P            D  +   ++E    ++ 
Sbjct: 23607 RFRVLACNAGGPGEPAEVPGTVKVTEMLEYP------------DYELDERYQEGIFVRQ- 23653

Query: 769   VGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLV-TGQSYIFRVRAVNAAGLS------- 820
              G  I  ++   GK  P      +G   +   ++ T +++   V      G S       
Sbjct: 23654 -GGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVL 23712

Query: 821   EYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPN 880
             E     +A+ +K  + G  +    P   D+   +     RV    P       +LG    
Sbjct: 23713 ENKCGKKAVYIKVRVIGSPNSPEGPLEYDD---IQVRSVRVSWRPPADDGGADILGYILE 23769

Query: 881   KPSLPSSSQNLGQTEVSKVSETVQE---------ELTPPPQKAAPQGKSKSDPLKKKTDR 931
             +  +P ++     + V   S  V+           ++   Q    +     +P+  KT  
Sbjct: 23770 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 23829

Query: 932   APPSPPCDIT-CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKA 990
              PP PP +    L+  + S+ L W +P   GG+ +TGYY+  +E       KW   N   
Sbjct: 23830 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKET---STDKWVRHNKTQ 23886

Query: 991   VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEV 1050
             ++   Y ++ L  +  YQF++ A N  GL   S  SE   C++     P  P  L+   +
Sbjct: 23887 ITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD-PFDKPSQPGELEILSI 23945

Query: 1051  RKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVS 1110
              KDS+ LQW+ P   G   + GY+V+ ++  + +  W+  N+  IK+    + GL E   
Sbjct: 23946 SKDSVTLQWEKPECDGGKEILGYWVEYRQ--SGDSAWKKSNKERIKDKQFTIGGLLEATE 24003

Query: 1111  YVFRVRAINQAGVGKPSDLAGPV----VAETRPGTKEVVVNVDDDGVISLNFECDKM-TP 1165
             Y FRV A N+ G+ +P   A  +     +   PG ++ + +V      +    C  +  P
Sbjct: 24004 YEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRP 24063

Query: 1166  KSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLID 1225
               +  W +       S + ++ S G    +T      +D G+Y+C       IA++ + +
Sbjct: 24064 LPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC-------IATNEVGE 24116

Query: 1226  EEELKRLLALSHEHKFPTVPVK--------SELAVEILEKGQ---VRFWMQAEKLSGNAK 1274
              E   +LL  +     P  P+K        S L + ++  G+      W   +KL  N++
Sbjct: 24117 VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE 24176

Query: 1275  VNYIFNEKEI-----------FEGPKYKMHIDRNTGIIEMFME-KLQDEDE 1313
                I N +                 KYK+ +    G ++  ++ ++QD+ +
Sbjct: 24177 NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPD 24227



 Score =  234 bits (597), Expect = 5e-61
 Identities = 319/1304 (24%), Positives = 521/1304 (39%), Gaps = 194/1304 (14%)

Query: 273   LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY 332
             L+  P F +   + TV   E++K+     G P P VTW+K+ VP+       +   ES  
Sbjct: 15647 LVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK---QTTRVNAESTE 15703

Query: 333   GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKG------EFDETRFHAGAS 386
                 L I     ED   Y     N  GE     +V+V    G      + DE      A 
Sbjct: 15704 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVT----AD 15759

Query: 387   TMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRN 446
             ++ LS+G   Y   S    +  +K D S                                
Sbjct: 15760 SITLSWGPPKYDGGSSINNYIVEKRDTS-------------------------------- 15787

Query: 447   GVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAE- 505
                   + W     +  R T+    L    E  Y  R+     Y + S Y+      A+ 
Sbjct: 15788 -----TTTWQIVSATVARTTIKACRLKTGCE--YQFRIAAENRYGK-STYLNSEPTVAQY 15839

Query: 506   ---IEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDT 562
                + G P  P+      +++D + + W +P  DGGS ++GY +++ E  +  W + N T
Sbjct: 15840 PFKVPGPPGTPVVTL---SSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKT 15896

Query: 563   PVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWT 622
             P+   +F  TGL EG  Y FRV A N +GIG PS+VSE   A DP +             
Sbjct: 15897 PIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDP------------ 15944

Query: 623   GQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTE 681
                            PG P  + VT   R+ V L WK P   G   I  Y VEK E    
Sbjct: 15945 ---------------PGRPEAIIVT---RNSVTLQWKKPTYDGGSKITGYIVEKKELPEG 15986

Query: 682   NWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV-GEPSEATEVTVVGDKLDIPK 740
              W + +    + +  F +  L E   Y FRV   N+AGV  EPSE+T      D++D P+
Sbjct: 15987 RWMKASFTNIIDT-HFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16045

Query: 741   APGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNN--PVKGSRF-- 796
                  +  +  DT VV + E  K   ++ G  I       G  E  N     +K + F  
Sbjct: 16046 IS---MDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFAT 16102

Query: 797   --TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGL 854
               +    V   S  + ++A N AG     + S  + VK     G  P   P +     G+
Sbjct: 16103 SLSVKDAVRVDSGNYILKAKNVAG-----ERSVTVNVKVLDRPG--PPEGPVVIS---GV 16152

Query: 855   TASRGRVHEASPPTFQKDA------LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQ-EEL 907
             TA +  +  A  P  Q         ++  +     + +      QT   KV++ ++  E 
Sbjct: 16153 TAEKCTL--AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEY 16210

Query: 908   TPPPQKAAPQGKSK---SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
             T         G  +   S+P+  K     P  P         +DSM++ W++P   GG+E
Sbjct: 16211 TFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSE 16270

Query: 965   ITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSA 1024
             I GY +  R+  +G+  +W   + + + E   +++ L EN  Y+F+V+A N AGL  PS 
Sbjct: 16271 ILGYVLEKRDK-EGI--RWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSP 16327

Query: 1025  VSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE 1084
              S   K  +  I  PGPP++ K  ++ + S+ L W  P++ G   + GY V+  +    E
Sbjct: 16328 PSAYQKACD-PIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGE 16386

Query: 1085  DQWRGLNE-AAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKE 1143
               W        I    ++V  L E   Y FR+ AIN+AGVG+ +D+ GP++ E +    +
Sbjct: 16387 --WTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPD 16444

Query: 1144  V--------VVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKM 1195
             +        ++N+   G + L F   K  P  E  W K      D+  ++V S  + T +
Sbjct: 16445 IDLDLELRKIINIRAGGSLRL-FVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSL 16501

Query: 1196  TFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEIL 1255
                ++   D G Y+  + ++ G  S+++       R+L        P+ PV   L V  +
Sbjct: 16502 VLDNVNRYDSGKYTLTLENSSGTKSAFV-----TVRVL------DTPSPPV--NLKVTEI 16548

Query: 1256  EKGQVRFWMQAEKLSGNAKV-NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEG 1314
              K  V    +   L G +K+ NYI  ++E     K    +  N       +++LQ   EG
Sbjct: 16549 TKDSVSITWEPPLLDGGSKIKNYIVEKREATR--KSYAAVVTNCHKNSWKIDQLQ---EG 16603

Query: 1315  -TYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECN 1373
              +Y F++    A N   + L       + K AE           P     ++ +     +
Sbjct: 16604 CSYYFRV---TAENEYGIGLPAQTADPI-KVAEV----------PQPPGKITVDDVTRNS 16649

Query: 1374  VLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTL--LITEFSKKDAGIYEVILK 1431
             V L          + I+ Y  E +    EK      + +L  +IT  ++ +  ++ V+  
Sbjct: 16650 VSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAV 16709

Query: 1432  DDRGKDKSRLKLVDEAFKELMMEVCKKIALSA------TDLKIQSTAEGIQLYSFVTYYV 1485
             +++G+   R   V    K+L++E   K A S+       DLKI+    G    +      
Sbjct: 16710 NEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPT------ 16763

Query: 1486  EDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY 1529
                 + W+ +G  ++ + R+    + +   L I E   +D G+Y
Sbjct: 16764 ----ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16803



 Score =  233 bits (595), Expect = 9e-61
 Identities = 261/1020 (25%), Positives = 403/1020 (39%), Gaps = 115/1020 (11%)

Query: 237   EKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKL 296
             E+K R  ++  K  +  +  T  + +     +  +  ++A   +   ++    E    + 
Sbjct: 16963 ERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARD 17022

Query: 297   HCSIAGWPEPRVTWYKNQVPIN----VHANPGK---YIIESRYGMHTLEINGCDFEDTAQ 349
              C   G PEP +   +N++ +     V+        YI+E R           D  D   
Sbjct: 17023 PCDPPGTPEP-IMVKRNEITLQWTKPVYDGGSMITGYIVEKR-----------DLPDGRW 17070

Query: 350   YRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFE---IH 406
              +AS  NV  E     S + +  + EF     +A  +    S    P       E   I 
Sbjct: 17071 MKASFTNVI-ETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRIS 17129

Query: 407   FDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERA 465
              D KF D      GET  L   V   P      P I+W R    +  S   +   +  +A
Sbjct: 17130 MDPKFRDTIVVNAGETFRLEADVHGKP-----LPTIEWLRGDKEIEESARCEIKNTDFKA 17184

Query: 466   TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
              L      + D G Y +R       + +   V V D      G P  P+ V  + + K  
Sbjct: 17185 LLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQVTGVTSEK-- 17238

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
               ++W  P  DGGS I  Y ++K E    +W+      V  +   VT L+EG  Y+FR+ 
Sbjct: 17239 CSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNS-LKVTKLLEGNEYVFRIM 17297

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             AVNK G+G P   S PV   +P                            ++PGPP  L 
Sbjct: 17298 AVNKYGVGEPLE-SAPVLMKNPF---------------------------VLPGPPKSLE 17329

Query: 646   VTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAE 704
             VT   +  + + W +P    G E I Y VEK +     W + N    +   R  +  L E
Sbjct: 17330 VTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRR-ITDLRLRVTGLTE 17388

Query: 705   GKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-- 762
                Y FRV   N+AGVGEPS AT      D +  P  P        T  S+ ++W +   
Sbjct: 17389 DHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIY 17448

Query: 763   KDAKELVGYYIEASVAGSGKWEPCN-NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSE 821
                 E++GY +E   A   +W+       ++ +RF    L   Q Y  RV A+N  GL E
Sbjct: 17449 DGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGE 17508

Query: 822   YSQDSEAIEVKAAIGGGVSPD---VCPAL---SDEPGGLTASRG---RVH---EASP-PT 868
                         ++ G V P+     P L   S+   G+    G   R+H   +  P P 
Sbjct: 17509 ----------ATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPE 17558

Query: 869   FQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKK 928
                    G   +K  +    + +  T++S +    + +      K      SKS  +  K
Sbjct: 17559 ITWSREEGEFTDKVQI---EKGVNYTQLS-IDNCDRNDAGKYILKLENSSGSKSAFVTVK 17614

Query: 929   TDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
                  P PP ++   E  +DS  L W+ P   GGA++  Y ++ RE       +   ANV
Sbjct: 17615 V-LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE-----STRKAYANV 17668

Query: 989   KA-VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKC 1047
              +  S+ ++K+ NL E  +Y F+V A N  G+G P    +  K  E     P PP  +  
Sbjct: 17669 SSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAE----PPSPPGKVTL 17724

Query: 1048  SEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKE 1107
             ++V + S  L W+ P H G + V GY V+++      ++W  + E+ + N    V GL  
Sbjct: 17725 TDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGT--EKWSIVAESKVCNAV--VTGLSS 17780

Query: 1108  GVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVVNVDDDGVISLNFECDKM- 1163
             G  Y FRV+A N+ G   P  L  PV+A+    +P  K             L  E   + 
Sbjct: 17781 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIG 17840

Query: 1164  TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
              P+   SW KD    + + R+ VE     T +  K+   DD G Y+   T++ G A+  L
Sbjct: 17841 RPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENL 17900



 Score =  233 bits (594), Expect = 1e-60
 Identities = 253/971 (26%), Positives = 389/971 (40%), Gaps = 143/971 (14%)

Query: 290   EKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQ 349
             E  N +L   I G P P V+W K + P+   A   +  +ES     TL +  C   D  +
Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWKKGEDPL---ATDTRVSVESSAVNTTLIVYDCQKSDAGK 13555

Query: 350   YRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFG-VTPYGYASRFEIHFD 408
             Y  +  NV G      S+ V              G  T P+ F  VT      ++    D
Sbjct: 13556 YTITLKNVAGTKEGTISIKVVG----------KPGIPTGPIKFDEVTAEAMTLKWAPPKD 13605

Query: 409   DKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLT 468
             D      G E           IT  I   +  +           +KWV    + ++ T  
Sbjct: 13606 DG-----GSE-----------ITNYILEKRDSVN----------NKWVTCASAVQKTTFR 13639

Query: 469   FSHLNKEDEGLYTIRVRMGEYY---EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
              + L++  E  YT RV     Y   E   +   V     ++  AP  P     ++   D 
Sbjct: 13640 VTRLHEGME--YTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPP---NIVDVRHDS 13694

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
             + ++W  P   GGSPI GY ++  E  +  W + N TP++   F VTGL EG  Y FRV 
Sbjct: 13695 VSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVM 13754

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             A+N  G+G PS  SEPV ALDP +                              PP    
Sbjct: 13755 AINLAGVGKPSLPSEPVVALDPID------------------------------PPGKPE 13784

Query: 646   VTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAE 704
             V   TR+ V L W +P    GH+   Y VEK +  +++W + N  + V    F + DL E
Sbjct: 13785 VINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKAN-HVNVPECAFTVTDLVE 13843

Query: 705   GKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESK 763
             G  Y FR+R  N+AG +  PSE+TE  +  D+ +   AP  ++     D   +    ++ 
Sbjct: 13844 GGKYEFRIRAKNTAGAISAPSESTETIICKDEYE---APTIVLDPTIKDGLTI----KAG 13896

Query: 764   DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823
             D   L    I         W     + ++ S  T     T  S +  ++        EY+
Sbjct: 13897 DTIVLNAISILGKPLPKSSWSKAGKD-IRPSDIT-QITSTPTSSMLTIKYATRKDAGEYT 13954

Query: 824   QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPS 883
                  I      G  V   V   + D PG      G V E S  + +K  L  + P +  
Sbjct: 13955 -----ITATNPFGTKVE-HVKVTVLDVPG----PPGPV-EISNVSAEKATLTWTPPLEDG 14003

Query: 884   -LPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQ-----------------GKSK---S 922
               P  S  L + E S++  TV  E     +  A +                 GK +   S
Sbjct: 14004 GSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQS 14063

Query: 923   DPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGK 982
             +P+K      PP PP         +++  + WK+P   GG+EITGY+V  RE       +
Sbjct: 14064 EPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSL---R 14120

Query: 983   WREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPP 1042
             W  A    VS+   K++ L+E   Y+F+V+A N AG+G PS  S+    ++     PGPP
Sbjct: 14121 WVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD-AAYPPGPP 14179

Query: 1043  HSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW-RGLNEAAIKNVYLK 1101
              +   ++  K S  L W  P + G   +TGY V+    K  ++ W +     A++     
Sbjct: 14180 SNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVE--HQKVGDEAWIKDTTGTALRITQFV 14237

Query: 1102  VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG---------TKEVVVNVDDDG 1152
             V  L+    Y FR+ AIN AGVG+P+ +    + E              + +VV     G
Sbjct: 14238 VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRA---G 14294

Query: 1153  VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
             +    F   K  P  E +W+KD ++ ++  R  +E+  + T +   +    D G +   +
Sbjct: 14295 LSIRIFVPIKGRPAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTGKFVMTI 14352

Query: 1213  TDTDGIASSYL 1223
              +  G  S ++
Sbjct: 14353 ENPAGKKSGFV 14363



 Score =  233 bits (593), Expect = 2e-60
 Identities = 236/910 (25%), Positives = 381/910 (41%), Gaps = 117/910 (12%)

Query: 404   EIHFDDKF-DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG 462
             +I  D KF D    + GE   L   V   P      P ++W ++G  L  +  ++   + 
Sbjct: 14963 KIKVDVKFKDTVILKAGEAFRLEADVSGRPP-----PTMEWSKDGKELEGTAKLEIKIAD 15017

Query: 463   ERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEAN 522
                 L      + D G YT+       + ++   V V D      G P  PL V   E  
Sbjct: 15018 FSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRP----GPPEGPLAVT--EVT 15071

Query: 523   KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIF 582
              +  ++SW  P  DGG+ I  Y + K E    +W+    + V+  +  VT L++G  YIF
Sbjct: 15072 SEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIF 15130

Query: 583   RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
             RV AVNK G+G P   SEPV A++P                              P PP 
Sbjct: 15131 RVMAVNKYGVGEPLE-SEPVLAVNPYGP---------------------------PDPPK 15162

Query: 643   DLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFD 701
             +  VT  T+  +V+ W  P    G E I Y VE+ +   + W + N +  +   R+ +  
Sbjct: 15163 NPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT-LTDLRYKVSG 15221

Query: 702   LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEE 761
             L EG  Y FR+   N+AG+  PS  +      D +  P  PG       + +S+ ++W +
Sbjct: 15222 LTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNK 15281

Query: 762   S--KDAKELVGYYIEASVAGSGKWEPCNNNP-VKGSRFTCHGLVTGQSYIFRVRAVNAAG 818
                    E+ GY +E ++    +W+       +K + +T  GL   Q Y  R+ A+N+ G
Sbjct: 15282 PIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEG 15341

Query: 819   LSE--------YSQDS---EAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPP 867
             L E         ++D      IE+ A +   V+   C  L          +GR   A   
Sbjct: 15342 LGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRL----FVPIKGR--PAPEV 15395

Query: 868   TFQKDALLGSKPNKPSLPSSSQ-------NLGQTEVSKVSETVQEELTPPPQKAAPQGKS 920
              + +D   G   +K S+ S+S        N+ + +  K   TV+               S
Sbjct: 15396 KWARDH--GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENS-----------SGS 15442

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
             KS  +  +     P PP D+   E  + S+ L W  P   GG++I  Y V  RE      
Sbjct: 15443 KSAFVNVRV-LDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTR--- 15498

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
              K          + ++K+  L+E   Y F+V A N  G+G P+  +E  K  E     P 
Sbjct: 15499 -KAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASER----PL 15553

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYL 1100
             PP  +   +V ++S+ L W+ P H G + + GY V+++   +  D+W     A +K    
Sbjct: 15554 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGS--DKWATC--ATVKVTEA 15609

Query: 1101  KVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR--PGTKEVVVNV-----DDDGV 1153
              + GL +G  Y FRV A N+ G+  P  L+ PV+A+    P   +++ N       +D  
Sbjct: 15610 TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLK 15669

Query: 1154  ISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVT 1213
             + + F   + TP    +W KD V  + + R+  ES  N + +T KD   +D+G Y   +T
Sbjct: 15670 VDVPF-IGRPTPA--VTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLT 15726

Query: 1214  DTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
             ++ G A        E   ++ L      PT PVK +   E+        W   +   G++
Sbjct: 15727 NSAGEAI-------ETLNVIVLDKPGP-PTGPVKMD---EVTADSITLSWGPPKYDGGSS 15775

Query: 1274  KVNYIFNEKE 1283
               NYI  +++
Sbjct: 15776 INNYIVEKRD 15785



 Score =  232 bits (592), Expect = 2e-60
 Identities = 212/734 (28%), Positives = 309/734 (42%), Gaps = 93/734 (12%)

Query: 439  PEIQWYRNGVPLS-PSKWVQTLW-----SGERATLTFSHLNKEDEGLYTIRV--RMGEYY 490
            P+I+W +N   +  P+  +Q        S  +  L+     +ED+G YT+    R+G  +
Sbjct: 8931 PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVF 8990

Query: 491  EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCE 550
                     R+   E+   P+ P ++   +   +   ++W  P  +GGS I  Y IDK +
Sbjct: 8991 ---------RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRD 9041

Query: 551  VGTD--SWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPA 608
                   W +  +T V+  R+ +  LI    Y FRVRAVNK GI    + S+ V   DP 
Sbjct: 9042 ASRKKAEWEEVTNTAVE-KRYGIWKLIPNGQYEFRVRAVNKYGISDECK-SDKVVIQDPY 9099

Query: 609  EKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEG 668
                                        +PGPP    V   T+  +++SW PP   G   
Sbjct: 9100 R---------------------------LPGPPGKPKVLARTKGSMLVSWTPPLDNGGSP 9132

Query: 669  IM-YFVEKCEAGTENWQRVN----TELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEP 723
            I  Y++EK E G+  W RV+    T++ +K   F +  L EG  Y FR    N+AG+G P
Sbjct: 9133 ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPP 9192

Query: 724  SEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE-ESKD-AKELVGYYIEASVAGSG 781
            SE ++  V GD +  P  P        T +S+ + W+  +KD    + GY +E    G+ 
Sbjct: 9193 SEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTT 9252

Query: 782  KWEPCNNNPVKGSRFTCHGLVTG----QSYIFRVRAVNAAGLSEYSQDSEAI-------E 830
             W+   N P K    TC  +V      + Y FRV+AVN AG SE S  +  I       E
Sbjct: 9253 DWKRV-NEPDK-LITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEE 9310

Query: 831  VKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQN 890
             +  I  G    +      +       +GR    S   F   A    K     +P  +Q 
Sbjct: 9311 PEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQ- 9369

Query: 891  LGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAP---------PSPPCDIT 941
            L   E S V       +  P  K +  GK       K   +           P PP D+ 
Sbjct: 9370 LETAENSSV-------IIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK 9422

Query: 942  CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
              +  R S  L WK PD  GG  I GY +  R  IDG    W + N    S   + + +L
Sbjct: 9423 VSDITRGSCRLSWKMPDDDGGDRIKGYVIEKR-TIDG--KAWTKVNPDCGS-TTFVVPDL 9478

Query: 1002 KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
                 Y F+V A N  G+G P    +     +  I  P PP  LK   + K+++ L WKP
Sbjct: 9479 LSEQQYFFRVRAENRFGIGPPVETIQRTTARD-PIYPPDPPIKLKIGLITKNTVHLSWKP 9537

Query: 1062 PVHSGRTPVTGYFVDL---KEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAI 1118
            P + G +PVT Y V+         K++ WR  N+  ++ +   V  L EG  Y FRV+A+
Sbjct: 9538 PKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAV 9597

Query: 1119 NQAGVGKPSDLAGP 1132
            N AGV KPS   GP
Sbjct: 9598 NAAGVSKPSATVGP 9611



 Score =  228 bits (582), Expect = 3e-59
 Identities = 213/797 (26%), Positives = 332/797 (41%), Gaps = 96/797 (12%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVR--MGEYYEQYSAY 496
             P+  W + G  + PS   Q   +   + LT  +  ++D G YTI      G   E     
Sbjct: 13912 PKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVT 13971

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             V       ++ G P  P+++  + A K    ++W  P  DGGSPI  Y ++K E     W
Sbjct: 13972 VL------DVPGPPG-PVEISNVSAEK--ATLTWTPPLEDGGSPIKSYILEKRETSRLLW 14022

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             +  ++  ++  R   T LI+G  YIFRV AVN  G G P + SEPV  +D       +  
Sbjct: 14023 TVVSED-IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVD-------RFG 14073

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
             P                    PGPP    V+  T++   +SWK P   G   I  Y VE+
Sbjct: 14074 P--------------------PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVER 14113

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  W R   + PV   R  +  L EG +Y FRV   N AG+G PSEA++  ++ D 
Sbjct: 14114 REKKSLRWVRA-IKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA 14172

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEESK--DAKELVGYYIEASVAGSGKW-EPCNNNPVK 792
                P  P     +  T  S  ++W +       E+ GY +E    G   W +      ++
Sbjct: 14173 AYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALR 14232

Query: 793   GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS--QDSEAIEVKAAIGGGVSPDVCPALSDE 850
              ++F    L T + Y FR+ A+N AG+ E +   D E +E + A    +  ++   L   
Sbjct: 14233 ITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVR 14292

Query: 851   PGG----LTASRGRVHEASPPTFQKDAL-LGSKPNKPSLPSSS----QNLGQTEVSKVSE 901
              G         +GR   A   T+ KD + L ++ N  +  S +        + +  K   
Sbjct: 14293 AGLSIRIFVPIKGR--PAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 14350

Query: 902   TVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIG 961
             T++           P GK       +  D   P P  ++   +  +DS+ L W  P   G
Sbjct: 14351 TIEN----------PAGKKSGFVNVRVLDT--PGPVLNLRPTDITKDSVTLHWDLPLIDG 14398

Query: 962   GAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGA 1021
             G+ IT Y V  RE        +  A  K   +  YK++ L E   Y F+V A N  G+G 
Sbjct: 14399 GSRITNYIVEKREA---TRKSYSTATTKC-HKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14454

Query: 1022  PSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAK 1081
             P+  +E  K  E     P PP SL   ++ K ++ L W  P H G + +TGY ++ +  +
Sbjct: 14455 PTETTEPVKASE----APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQ--R 14508

Query: 1082  AKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGT 1141
                DQW  +    +K +   VR L EG  Y F+V A+N AG   P + + PV+ + +   
Sbjct: 14509 KGSDQWTHI--TTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPVIVKEQTML 14565

Query: 1142  KE----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGN 1191
              E          V+    D+  + +        PK   +W K     + + R+  E+   
Sbjct: 14566 PELDLRGIYQKLVIAKAGDNIKVEIPV---LGRPKPTVTWKKGDQILKQTQRVNFETTAT 14622

Query: 1192  KTKMTFKDLGMDDLGIY 1208
              T +   +    D G Y
Sbjct: 14623 STILNINECVRSDSGPY 14639



 Score =  227 bits (579), Expect = 6e-59
 Identities = 229/893 (25%), Positives = 362/893 (40%), Gaps = 102/893 (11%)

Query: 425   GCRVVITPEIKHFQ-PEIQWYR-------NGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             G  V I  +IK    P + W++       N  P+     V  L   +  TL      + D
Sbjct: 9634  GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9693

Query: 477   EGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPA 534
              GLYTI     +G   ++    V  R       G P  P+  + + A  D + +SW  P 
Sbjct: 9694  TGLYTITAVNNLGTASKEMRLNVLGRP------GPPVGPIKFESVSA--DQMTLSWFPPK 9745

Query: 535   VDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGF 594
              DGGS I  Y I+K E    +W   +  P K   + +  L+EG  Y+FR+ A NK GIG 
Sbjct: 9746  DDGGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9804

Query: 595   PSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYV 654
             P         LD           S P T + + +        VPG P   +V+  TR+ +
Sbjct: 9805  P---------LD-----------SEPETARNLFS--------VPGAPDKPTVSSVTRNSM 9836

Query: 655   VLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR----FALFDLAEGKSYC 709
              ++W+ P   G   +  Y++E  +  ++ W+RVN + P+K+      + +  L EG  Y 
Sbjct: 9837  TVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRD-PIKAMTLGVSYKVTGLIEGSDYQ 9895

Query: 710   FRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES-KDA-KE 767
             FRV   N+AGVG  S  ++     D +  P  P   +    T +S  + W    KD   +
Sbjct: 9896  FRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW-TKSSADLEWSPPLKDGGSK 9954

Query: 768   LVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 827
             + GY +E    G  +WE   +  V+G++    GL  G  Y FRVRAVN AG+ E  + ++
Sbjct: 9955  VTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD 10014

Query: 828   AIEVKAAIGGGVSPD------VCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNK 881
              IE+K  +   VSPD      V   +    GG+      V    PPT   +    + P +
Sbjct: 10015 VIEMKDRL---VSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQE 10071

Query: 882   PSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDIT 941
              ++ +++  +  + V K  +   + +     K     + K+  +       P   P    
Sbjct: 10072 ATIETTA--ISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTP--FL 10127

Query: 942   CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
                   +S  L W  P+  GG+ IT Y +  RE        W         + A  +  L
Sbjct: 10128 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRE---SDRRAWTPVTYTVTRQNA-TVQGL 10183

Query: 1002  KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
              +   Y F++AA N  G+G     SE     E  I VP  P  L+  EV K+++ L W P
Sbjct: 10184 IQGKAYFFRIAAENSIGMGPFVETSEALVIRE-PITVPERPEDLEVKEVTKNTVTLTWNP 10242

Query: 1062  PVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA 1121
             P + G + +  Y ++       E   +  N+  +   Y  V+GLKEG +Y +RV A+N  
Sbjct: 10243 PKYDGGSEIINYVLE-SRLIGTEKFHKVTNDNLLSRKY-TVKGLKEGDTYEYRVSAVNIV 10300

Query: 1122  GVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMT------PKSEFSWSKDY 1175
             G GKPS    P+  +       + ++  D   I +  E   +T      PK + SW KD 
Sbjct: 10301 GQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVG-EAFALTGRYSGKPKPKVSWFKDE 10359

Query: 1176  VSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSY----LIDEEELKR 1231
                 +  R  +++      +        D G Y   V ++ G    +    ++D      
Sbjct: 10360 ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR----- 10414

Query: 1232  LLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEI 1284
                       P  PV      E+ +   V  W       G+   NYI  +KE+
Sbjct: 10415 ----------PGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEV 10457



 Score =  225 bits (574), Expect = 2e-58
 Identities = 218/877 (24%), Positives = 354/877 (40%), Gaps = 106/877 (12%)

Query: 367   VVVKRYKGEFDETRFHAGASTM-----PLSFGVTPYGYASRFEIHFDDKFDVSFGREGET 421
             V+ +   G F E     GA T      P    + P  Y     +H  + F V     G+ 
Sbjct: 16016 VIARNAAGVFSEPSESTGAITARDEVDPPRISMDPK-YKDTIVVHAGESFKVDADIYGKP 16074

Query: 422   MSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYT 481
             +                P IQW +    LS +  ++   +    +L+     + D G Y 
Sbjct: 16075 I----------------PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYI 16118

Query: 482   IRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPI 541
             ++ +        +  V V D      G P  P+ +  + A K    ++WK P  DGGS I
Sbjct: 16119 LKAKNVAGERSVTVNVKVLDRP----GPPEGPVVISGVTAEK--CTLAWKPPLQDGGSDI 16172

Query: 542   LGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEP 601
             + Y +++ E     W+   D  V+     VT L+EG  Y FR+ AVNK G+G P   SEP
Sbjct: 16173 INYIVERRETSRLVWTVV-DANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLE-SEP 16230

Query: 602   VAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPP 661
             V A +P                            +VP  P    VT  T+  +++ W+ P
Sbjct: 16231 VVAKNPF---------------------------VVPDAPKAPEVTTVTKDSMIVVWERP 16263

Query: 662   GQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGV 720
                G   I+ Y +EK +     W R +  L +   R  +  L E   Y FRV   N+AG+
Sbjct: 16264 ASDGGSEILGYVLEKRDKEGIRWTRCHKRL-IGELRLRVTGLIENHDYEFRVSAENAAGL 16322

Query: 721   GEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVA 778
              EPS  +      D +  P  P        T +SV +SW +       E+ GY +E    
Sbjct: 16323 SEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDV 16382

Query: 779   GSGKWEPCNN-NPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGG 837
               G+W  C     +  +      L+    Y FR+ A+N AG+ E++     I V+  +  
Sbjct: 16383 SVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEA 16442

Query: 838   ---GVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQ----- 889
                 +  ++   ++   GG       +     P  +   + G   +   +  +S      
Sbjct: 16443 PDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV 16502

Query: 890   --NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFR 947
               N+ + +  K + T++             G   +    +  D   PSPP ++   E  +
Sbjct: 16503 LDNVNRYDSGKYTLTLENS----------SGTKSAFVTVRVLDT--PSPPVNLKVTEITK 16550

Query: 948   DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY 1007
             DS+ + W+ P   GG++I  Y V  RE       K   A V    + ++KI  L+E   Y
Sbjct: 16551 DSVSITWEPPLLDGGSKIKNYIVEKREATR----KSYAAVVTNCHKNSWKIDQLQEGCSY 16606

Query: 1008  QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 1067
              F+V A N  G+G P+  ++  K  E    VP PP  +   +V ++S+ L W  P H G 
Sbjct: 16607 YFRVTAENEYGIGLPAQTADPIKVAE----VPQPPGKITVDDVTRNSVSLSWTKPEHDGG 16662

Query: 1068  TPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS 1127
             + +  Y V++ +AK  E +W     A +K++   +  L +G  Y+FRV A+N+ G   P 
Sbjct: 16663 SKIIQYIVEM-QAKHSE-KWSEC--ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPR 16718

Query: 1128  DLAGPVVA-------ETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTED 1180
              LA P+VA       + +P      V V  D  I +        PK   +W+KD +  + 
Sbjct: 16719 SLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG---RPKPTITWTKDGLPLKQ 16775

Query: 1181  SPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             + R+ V    + T ++ K+   DD G Y   V +  G
Sbjct: 16776 TTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG 16812



 Score =  224 bits (572), Expect = 4e-58
 Identities = 288/1312 (21%), Positives = 517/1312 (39%), Gaps = 206/1312 (15%)

Query: 276   APEFIIKP------RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIE 329
             A + +I+P       S++V   +++K+   I+G P+P +TW K+ +P+       +  + 
Sbjct: 16726 AKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK---QTTRINVT 16782

Query: 330   SRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRY----KG--EFDETRFHA 383
                 + TL I     +D  QY  +  NV G+ +A   +V        KG  +FD+     
Sbjct: 16783 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDV---- 16838

Query: 384   GASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQW 443
              A ++ LS+    Y    +   +   K D +                             
Sbjct: 16839 SAESITLSWNPPLYTGGCQITNYIVQKRDTT----------------------------- 16869

Query: 444   YRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV---FVR 500
                      + W     +  R TL  + L    E  Y  R+     Y Q  A      V 
Sbjct: 16870 --------TTVWDVVSATVARTTLKVTKLKTGTE--YQFRIFAENRYGQSFALESDPIVA 16919

Query: 501   DADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCN 560
                 +  G P  P        +KD ++I W +P  +GGSP++GY +++ E  +  W++ N
Sbjct: 16920 QYPYKEPGPPGTPF---ATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVN 16976

Query: 561   DTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAP 620
              T +   +F    L EG  Y FRV A N +G+G  S+ SE   A DP +           
Sbjct: 16977 KTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDP---------- 17026

Query: 621   WTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAG 679
                              PG P  + V    R+ + L W  P   G   I  Y VEK +  
Sbjct: 17027 -----------------PGTPEPIMVK---RNEITLQWTKPVYDGGSMITGYIVEKRDLP 17066

Query: 680   TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDI 738
                W + +    +++ +F +  L E + Y FRV   N+AG + +PS++T      D++++
Sbjct: 17067 DGRWMKASFTNVIET-QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVEL 17125

Query: 739   PKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEAS--VAGSGKWEPCNNNPVKGSRF 796
             P+     +  +  DT VV + E  +   ++ G  +     + G  + E      +K + F
Sbjct: 17126 PRIS---MDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17182

Query: 797   TCHGLVT------GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGG-----GVSPDVC- 844
                 +V       G  YI  +RA N AG   +  + + ++      G     GV+ + C 
Sbjct: 17183 KALLIVKDAIRIDGGQYI--LRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17240

Query: 845   ----PALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVS 900
                 P L D  GG   S   V +          ++ S+    SL  +    G   V ++ 
Sbjct: 17241 LTWSPPLQD--GGSDISHYVVEKRETSRLAW-TVVASEVVTNSLKVTKLLEGNEYVFRIM 17297

Query: 901   ETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKI 960
                +  +  P + A         P+  K     P PP  +      +DSM + W +PD  
Sbjct: 17298 AVNKYGVGEPLESA---------PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSD 17348

Query: 961   GGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLG 1020
             GG+EI GY V  R+   G+  +W + N + +++   +++ L E+  Y+F+V+A N AG+G
Sbjct: 17349 GGSEIIGYIVEKRD-RSGI--RWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVG 17405

Query: 1021  APSAVSECFK-CEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
              PS  +  +K C+   +  PGPP +    +  K+S+ L W  P++ G + + GY V++  
Sbjct: 17406 EPSPATVYYKACD--PVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEI-- 17461

Query: 1080  AKAKEDQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR 1138
              KA E++W+ +  +  ++    ++  L E   Y  RV A+N+ G+G+ + + G V  E +
Sbjct: 17462 CKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDK 17521

Query: 1139  PGTKE----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVES 1188
                 E          +VV       I + F   K  P  E +WS++    E + ++++E 
Sbjct: 17522 LEAPELDLDSELRKGIVVRAGGSARIHIPF---KGRPTPEITWSRE--EGEFTDKVQIEK 17576

Query: 1189  KGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKS 1248
               N T+++  +   +D G Y   + ++ G  S+++  +                T     
Sbjct: 17577 GVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVK-------------VLDTPGPPQ 17623

Query: 1249  ELAVEILEKGQVRFWMQAEKLSGNAKV-NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEK 1307
              LAV+ + K       +   + G AKV NY+ +++E     K   ++          +E 
Sbjct: 17624 NLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE--STRKAYANVSSKCSKTSFKVEN 17681

Query: 1308  LQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWE 1367
             L   +   Y F++           V   D  K  +               P     ++  
Sbjct: 17682 L--TEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP--------------PSPPGKVTLT 17725

Query: 1368  VTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGI 1425
                + +  L  +       + ++ Y  E +    EK     +  +C  ++T  S      
Sbjct: 17726 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 17785

Query: 1426  YEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIAL------SATDLKIQSTAEGIQLYS 1479
             + V   +++GK   R+  V    K+L ++   K+        +  DLKI+    G    +
Sbjct: 17786 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPN 17845

Query: 1480  FVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
                       ++W  +G  ++ + RV    T     L I E   +D GKY +
Sbjct: 17846 ----------ISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 17887



 Score =  219 bits (558), Expect = 2e-56
 Identities = 202/716 (28%), Positives = 292/716 (40%), Gaps = 101/716 (14%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTP-VKFAR 568
             P  P + + L+ ++  I I+W +P  DGGS I GY ++      D W        +K   
Sbjct: 15259 PGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATS 15318

Query: 569   FPVTGLIEGRSYIFRVRAVNKMGIGFPS----------RVSEPVAALD------------ 606
             + +TGL E + Y  R+ A+N  G+G P+          R+  P   LD            
Sbjct: 15319 YTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRAC 15378

Query: 607   ------------PA-------------EKARLKSRPSAPW----------TGQIIVTEEE 631
                         PA             +KA ++S  S             +G+ I+T E 
Sbjct: 15379 CTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVEN 15438

Query: 632   PSEGI----------VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGT 680
              S              PGPP DL V E T++ V L+W PP   G   I  Y VEK E+  
Sbjct: 15439 SSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTR 15498

Query: 681   ENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
             + +  V T     S  + +  L EG SY FRV   N  G+G P+E  E     ++   P 
Sbjct: 15499 KAYSTVATNCHKTS--WKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASER---PL 15553

Query: 741   APGKIIPSRNTDTSVVVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTC 798
              PGKI     T  SV +SWE  E      ++GY +E    GS KW  C    VK +  T 
Sbjct: 15554 PPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCAT--VKVTEATI 15611

Query: 799   HGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASR 858
              GL+ G+ Y FRV A N  G+S+  Q S  +  K  +       + PA        T   
Sbjct: 15612 TGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV-------IPPAFKLLFNTFTVLA 15664

Query: 859   GRVHEASPPTFQK--DALLGSKPNKPSLPSSSQNLGQTE---VSKVSETVQEELTPPPQK 913
             G   +   P   +   A+   K N P   ++  N   TE   +  + +  +E++     K
Sbjct: 15665 GEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVK 15724

Query: 914   AAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYR 973
                      + L       P  P   +   E   DS+ L W  P   GG+ I  Y V  R
Sbjct: 15725 LTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKR 15784

Query: 974   EVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE 1033
                D     W+  +   V+    K   LK    YQF++AA N    G  + ++      +
Sbjct: 15785 ---DTSTTTWQIVSA-TVARTTIKACRLKTGCEYQFRIAAENR--YGKSTYLNSEPTVAQ 15838

Query: 1034  WTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
             +   VPGPP +   +   +DS+ +QW  P+  G + V GY ++ KE  +    W  LN+ 
Sbjct: 15839 YPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNS--ILWVKLNKT 15896

Query: 1094  AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVV 1146
              I     K  GL+EGV Y FRV A N  G+GKPS ++   VA      PG  E ++
Sbjct: 15897 PIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAII 15952



 Score =  219 bits (557), Expect = 2e-56
 Identities = 204/808 (25%), Positives = 322/808 (39%), Gaps = 89/808 (11%)

Query: 439   PEIQWYRN--GVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAY 496
             PE+ W ++     L+ S  V+     + +  + +   + D G Y +           +A 
Sbjct: 11734 PEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATN-------TAG 11786

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
              FV  A   +   P    ++K ++ + D   + W  P  DGG  I  Y ++KCE     W
Sbjct: 11787 SFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW 11846

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             S  + T V      VT LIEG  YIFRVRA NK+G G P+  S+PV A    +K      
Sbjct: 11847 STYSAT-VLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTE-SKPVIAKTKYDK------ 11898

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
                                  PG P    VT+ ++  + + W PP   G + I  YF+EK
Sbjct: 11899 ---------------------PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEK 11937

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  W  VN +  +   R  + +L     Y FRV+  N  G+GEPS  +   V  D 
Sbjct: 11938 KEKHSTRWVPVN-KSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDP 11996

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIE-----ASVAGSGKWEPCN- 787
             ++ P  P        T  S+ + W +        ++GY +E     A  +    W+ CN 
Sbjct: 11997 IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNA 12056

Query: 788   NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPAL 847
                +    FT   L   Q Y FRV A N  G+   ++  EAI+ K  +     P++    
Sbjct: 12057 AAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEIL---EPPEI---- 12109

Query: 848   SDEPGGLTASRGR--VHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSET--- 902
                   L AS  +  +  A  P      L      +P+   + + +G   V +  +    
Sbjct: 12110 -----DLDASMRKLVIVRAGCPI----RLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLV 12160

Query: 903   -VQEELTPPPQKAAPQGKSKSDPLKKKTDRA---------PPSPPCDITCLESFRDSMVL 952
                  L  P       GK     +    ++A          P P  D+   +  + S  +
Sbjct: 12161 DTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHV 12220

Query: 953   GWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVA 1012
              W  P+  GG+++T Y V  RE       K        V + ++ ++NL     Y F+V 
Sbjct: 12221 SWAPPENDGGSQVTHYIVEKRE----ADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVT 12276

Query: 1013  AMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTG 1072
             A+N  G G P+ V +     +  ++ P PP  L+ +E+ K+S  L W PP+  G   + G
Sbjct: 12277 AVNEYGPGVPTDVPKPVLASD-PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12335

Query: 1073  YFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGP 1132
             Y    +E +   D+W     + +K++ L V GLKEG  Y FRV A N  GV  P +  G 
Sbjct: 12336 YITSYREEEQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGV 12393

Query: 1133  VVAETRPGTKEVVV--NVDDDGVISLNFECDKM-TPKSEFSWSKDYVSTEDSPRLEVESK 1189
               A+ +    ++++   +       L  E      P     W K       S  L V   
Sbjct: 12394 YEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKA 12453

Query: 1190  GNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
              + + +  KD+   D G YS    ++ G
Sbjct: 12454 DSSSILIIKDVTRKDSGYYSLTAENSSG 12481



 Score =  216 bits (551), Expect = 1e-55
 Identities = 206/784 (26%), Positives = 323/784 (41%), Gaps = 104/784 (13%)

Query: 475   EDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPA 534
             ED G+Y++ V      +  S  V V D        P  P D++  E  KD   ++WK+P 
Sbjct: 10785 EDGGIYSLTVENPAGSKTVSVKVLVLDK-------PGPPRDLEVSEIRKDSCYLTWKEPL 10837

Query: 535   VDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGF 594
              DGGS I  Y +++ +V +  WS  + T  K + F    L EG  Y+FRV A N+ G G 
Sbjct: 10838 DDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAENQYGRGP 10896

Query: 595   PSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYV 654
                  +P+ ALDP                              PGPP DL   +  ++ V
Sbjct: 10897 FVETPKPIKALDPLHP---------------------------PGPPKDLHHVDVDKTEV 10929

Query: 655   VLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVR 713
              L W  P + G   I  Y VE  E GT++W +  T   V +    +  L +GK+Y FRV+
Sbjct: 10930 SLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKT---VTNLECVVTGLQQGKTYRFRVK 10986

Query: 714   CSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYI 773
               N  G+G P   T + +   +  +P       PS   D  ++                I
Sbjct: 10987 AENIVGLGLPD--TTIPIECQEKLVP-------PSVELDVKLIEGLVVKAGTTVRFPAII 11037

Query: 774   EASVAGSGKWEPCNNNPVKGSRFT--------------CHGLVTGQSYIFRVRAVNAAGL 819
                   + KW    +       +T              C    TG+   +++   NAAG 
Sbjct: 11038 RGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGE---YQITVSNAAGS 11094

Query: 820   SEYSQDSEAIEVKAAIGGGVSP-DVCP---ALSDEP----GGLTASRGRVHEASPPTFQK 871
                +     ++V     G ++  DV P    +S +P    GG       V +      +K
Sbjct: 11095 KTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDT---RK 11151

Query: 872   DA--LLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKT 929
             D   ++ S  +K  L       G   V +V    +  + PP           S P   K 
Sbjct: 11152 DTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLD---------STPTVAKH 11202

Query: 930   DRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVK 989
               +PPSPP      +   ++  + W  P   GG+ ITGYY+  RE    V GKW   N  
Sbjct: 11203 KFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERRE----VTGKWVRVNKT 11258

Query: 990   AVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK-CEEWTIAVPGPPHSLKCS 1048
              +++  ++++ L E   Y+F+V A N+AGL  PS  S+  K C    I  PGPP + K  
Sbjct: 11259 PIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACR--PIKPPGPPINPKLK 11316

Query: 1049  EVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRGLKE 1107
             +  +++  L W  P+  G +P+ GY V+ +  K    QW  +N +  I+    +V GL E
Sbjct: 11317 DKSRETADLVWTKPLSDGGSPILGYVVECQ--KPGTAQWNRINKDELIRQCAFRVPGLIE 11374

Query: 1108  GVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN-------FEC 1160
             G  Y FR++A N  G G+P +LA  V+A+      EV ++V    VI++           
Sbjct: 11375 GNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILAR 11434

Query: 1161  DKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
              K  P+ + +W+K+        R+++     + ++  K+    D G Y     ++ G A 
Sbjct: 11435 VKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQ 11494

Query: 1221  SYLI 1224
                I
Sbjct: 11495 GSAI 11498



 Score =  216 bits (550), Expect = 1e-55
 Identities = 215/827 (25%), Positives = 330/827 (39%), Gaps = 99/827 (11%)

Query: 417   REGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKED 476
             R G TM L   V   P      P+I W +  V L     +    +     L   ++NK D
Sbjct: 13209 RAGVTMRLYVPVKGRPP-----PKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYD 13263

Query: 477   EGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVD 536
              G Y + +      ++Y+  V V D        P  P++V   E +KD   ++W+ P +D
Sbjct: 13264 AGKYILTLENSCGKKEYTIVVKVLDT-------PGPPVNVTVKEISKDSAYVTWEPPIID 13316

Query: 537   GGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPS 596
             GGSPI+ Y + K +    SWS    T      F V  L EG+SY FRV A N+ GIG P 
Sbjct: 13317 GGSPIINYVVQKRDAERKSWSTVT-TECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPG 13375

Query: 597   RVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVL 656
                + V A                                 PGP  DL V   ++S   +
Sbjct: 13376 ETRDAVKASQ------------------------------TPGPVVDLKVRSVSKSSCSI 13405

Query: 657   SWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSN 716
              WK P   G   I+ +V         WQRV   L   S +++  DL EGK Y FRV   N
Sbjct: 13406 GWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSL---SLQYSAKDLTEGKEYTFRVSAEN 13462

Query: 717   SAGVGEPSEATEVT---VVGDKLDIPKAPGKIIPSRNTDT-----------SVVVSWEES 762
               G G PSE T V    VV   LD+   P     ++               +  VSW++ 
Sbjct: 13463 ENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG 13522

Query: 763   KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEY 822
             +D        +      S +    N   +    + C     G+   + +   N AG  E 
Sbjct: 13523 EDP-------LATDTRVSVESSAVNTTLIV---YDCQKSDAGK---YTITLKNVAGTKE- 13568

Query: 823   SQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKP 882
                + +I+V    G    P     ++ E   L  +  +    S  T        S  NK 
Sbjct: 13569 --GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKW 13626

Query: 883   SLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-KSDPLKKKTDRAPPSPPCDIT 941
                +S+       V+++ E ++       +     G+  KS+P+  +     P  P    
Sbjct: 13627 VTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPN 13686

Query: 942   CLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNL 1001
              ++   DS+ L W  P K GG+ ITGY++ ++E    +   W+ AN   +    +K++ L
Sbjct: 13687 IVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL---WKRANKTPIRMRDFKVTGL 13743

Query: 1002  KENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP 1061
              E + Y+F+V A+N+AG+G PS  SE     +  I  PG P  +    + ++S+ L W  
Sbjct: 13744 TEGLEYEFRVMAINLAGVGKPSLPSEPVVALD-PIDPPGKPEVI---NITRNSVTLIWTE 13799

Query: 1062  PVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA 1121
             P + G   +TGY V+ ++  +K   W   N   +      V  L EG  Y FR+RA N A
Sbjct: 13800 PKYDGGHKLTGYIVEKRDLPSK--SWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 13857

Query: 1122  G-VGKPSDLAGPVVAETR---------PGTKE-VVVNVDDDGVISLNFECDKMTPKSEFS 1170
             G +  PS+    ++ +           P  K+ + +   D  V++      K  PKS  S
Sbjct: 13858 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKS--S 13915

Query: 1171  WSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             WSK       S   ++ S    + +T K     D G Y+   T+  G
Sbjct: 13916 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962



 Score =  216 bits (550), Expect = 1e-55
 Identities = 203/835 (24%), Positives = 345/835 (41%), Gaps = 98/835 (11%)

Query: 411   FDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFS 470
             FD    + GE++ +   V   P      P + W+++GV +     ++        +L   
Sbjct: 21468 FDGLIIKSGESLRIKALVQGRPV-----PRVTWFKDGVEIEKRMNMEITDVLGSTSLFVR 21522

Query: 471   HLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISW 530
                ++  G+YT+  +      +    V V+D   ++ G       ++      + + + W
Sbjct: 21523 DATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGP------IRFTNITGEKMTLWW 21576

Query: 531   KQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKM 590
               P  DG +PI  Y I+K E    +W+   D   +   +    LI G  Y FRV AVNK 
Sbjct: 21577 DAPLNDGCAPITHYIIEKRETSRLAWALIEDK-CEAQSYTAIKLINGNEYQFRVSAVNKF 21635

Query: 591   GIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEAT 650
             G+G P   S+PV A                   QI  T        VP  P     +  T
Sbjct: 21636 GVGRPLD-SDPVVA-------------------QIQYT--------VPDAPGIPEPSNIT 21667

Query: 651   RSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYC 709
              + + L+W +P    G E   Y +E+ E  +  W +V ++ P+   RF +  L EG  Y 
Sbjct: 21668 GNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYE 21727

Query: 710   FRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKE 767
             F V   N+AGVG  S  + +    + ++ P  P  +  +  + T+V + W +       E
Sbjct: 21728 FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGME 21787

Query: 768   LVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 827
             ++GY IE   A  G W   N      +R+T   L  G+ Y FRV A+N AG  +  + + 
Sbjct: 21788 IIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTG 21847

Query: 828   AIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV-----HEASP-PT---FQKDALLGSK 878
              I+   A+    +P++    + +   +  +   +     ++  P PT    + D+ L  +
Sbjct: 21848 TIK---AVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLR 21904

Query: 879   PNKPSLPSSS----QNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPP 934
              +  +  S S    +N  + +  K + TV+               SKS     K     P
Sbjct: 21905 ADIHTTDSFSTLTVENCNRNDAGKYTLTVEN-----------NSGSKSITFTVKV-LDTP 21952

Query: 935   SPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEE 994
              PP  IT  +  R S  L W  P   GGA I  Y V  RE        W+  + K  + +
Sbjct: 21953 GPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKRE---ASRRSWQVISEKC-TRQ 22008

Query: 995   AYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDS 1054
              +K+++L E + Y F+V+A+N  G+G P  + E     E     P PP  L   +  K S
Sbjct: 22009 IFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATE----QPAPPRRLDVVDTSKSS 22064

Query: 1055  LVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFR 1114
              VL W  P H G + +TGY +++++  +  D W  +     K +   V  L E   Y FR
Sbjct: 22065 AVLAWLKPDHDGGSRITGYLLEMRQKGS--DFW--VEAGHTKQLTFTVERLVEKTEYEFR 22120

Query: 1115  VRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMT---------- 1164
             V+A N AG  +P +    V+ +      ++    D  G+ +    C   +          
Sbjct: 22121 VKAKNDAGYSEPREAFSSVIIK----EPQIEPTADLTGITNQLITCKAGSPFTIDVPISG 22176

Query: 1165  -PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGI 1218
              P  + +W  + +  +++ R+ + +  ++T +T KD    D G Y   + +T G+
Sbjct: 22177 RPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGV 22231



 Score =  209 bits (533), Expect = 1e-53
 Identities = 206/802 (25%), Positives = 328/802 (40%), Gaps = 99/802 (12%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVR--MGEYYEQYSAY 496
             P I+WY++   L  +  V    + + A++     ++ + G Y +++R  MG      SA 
Sbjct: 20405 PTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMG------SAS 20458

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
               +R    +  G P  P++ K + A K  I + W+ PA DGG+ I  Y ++K E     W
Sbjct: 20459 ATIRVQILDKPGPPGGPIEFKTVTAEK--ITLLWRPPADDGGAKITHYIVEKRETSRVVW 20516

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
             S  ++  ++      T +I+G  YIFRVRAVNK GIG P      VA             
Sbjct: 20517 SMVSE-HLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVA------------- 20562

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
                             +  + PGPP    VT+ T++ + + W  P   G   I  YF+EK
Sbjct: 20563 ---------------KNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEK 20607

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              +  +  W +V  E  ++  R  +  L E   Y +RV   N+AG G  SE +E     D 
Sbjct: 20608 RDKKSLGWFKVLKE-TIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADP 20666

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCN-NNPVK 792
             +D P  P KI  + +T +S+ + W +        + GY +E       +W   +    V+
Sbjct: 20667 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20726

Query: 793   GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPG 852
              + +    L  G +Y FRV AVN AG  E  + +E ++ K  +    +P++   ++    
Sbjct: 20727 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDIL---EAPEIDLDVALRTS 20783

Query: 853   GLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQ 912
              +  +   V    P         G  P   +     +NLG      +  T    L   PQ
Sbjct: 20784 VIAKAGEDVQVLIP-------FKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQ 20836

Query: 913   KAAPQ------------GKSKSDPLKKKTDRAPPSPPCD-ITCLESFRDSMVLGWKQPDK 959
                              G+ KS  +  K    P +  C  +      R ++ L W  P  
Sbjct: 20837 VTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAA--CQKLQVKHVSRGTVTLLWDPPLI 20894

Query: 960   IGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GG+ I  Y +  R   D     W   + K  S  ++K+ +L E   + F+V A N  G+
Sbjct: 20895 DGGSPIINYVIEKR---DATKRTWSVVSHKC-SSTSFKLIDLSEKTPFFFRVLAENEIGI 20950

Query: 1020  GAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 1079
             G P   +E  K  E    VP P   L   +  K S++L W  P   G + +T Y V   E
Sbjct: 20951 GEPCETTEPVKAAE----VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---E 21003

Query: 1080  AKAKEDQ-WRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETR 1138
              K K +Q W   +    K   ++V  LKE     FRV A N+ G+  P  + GP+  +  
Sbjct: 21004 RKGKGEQTWS--HAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI-GPITVKEL 21060

Query: 1139  -----------PGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVE 1187
                        PG  +V V +  +  + L +   K  PK   SW KD +  ++S  +   
Sbjct: 21061 IITPEVDLSDIPGA-QVTVRIGHNVHLELPY---KGKPKPSISWLKDGLPLKESEFVRFS 21116

Query: 1188  SKGNKTKMTFKDLGMDDLGIYS 1209
                NK  ++ K+   +  G Y+
Sbjct: 21117 KTENKITLSIKNAKKEHGGKYT 21138



 Score =  206 bits (525), Expect = 1e-52
 Identities = 199/815 (24%), Positives = 338/815 (41%), Gaps = 110/815 (13%)

Query: 438   QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
             +PE++W +    L+    ++   +     L   ++ + D G Y + +      +  +A+V
Sbjct: 18639 EPEVKWEKAEGILTDRAQIEV--TSSFTMLVIDNVTRFDSGRYNLTLENNSGSK--TAFV 18694

Query: 498   FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
              VR  D+     P+AP+++   E  KD + +SW+ P +DGG+ I  Y ++K E    +++
Sbjct: 18695 NVRVLDS-----PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18749

Query: 558   QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRP 617
                +   K   F +  L EG SY FRV A N+ GIG P+  +EPV   +P          
Sbjct: 18750 TITNNCTK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP---------- 18798

Query: 618   SAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKC 676
                                 P PP  +++ + TR+   + W+ P   G   I  Y VE  
Sbjct: 18799 --------------------PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQ 18838

Query: 677   EAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
               G+E W   +T   VK+    +  L  G+ Y FRV   N  G  +P +   V V+   +
Sbjct: 18839 TKGSEKW---STCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG-VPVIARDI 18894

Query: 737   DIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRF 796
             +I   P   +P     T  V + E+ K     +    +     +  W        + +R 
Sbjct: 18895 EIK--PSVELPFH---TFNVKAREQLK-----IDVPFKGRPQATVNWRKDGQTLKETTRV 18944

Query: 797   TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTA 856
                   T  S   +  +    G  E    + A        G ++  +   + D PG    
Sbjct: 18945 NVSSSKTVTSLSIKEASKEDVGTYELCVSNSA--------GSITVPITIIVLDRPG--PP 18994

Query: 857   SRGRVHEAS---------PPTFQKDALLGSKPNKPSLPSS------SQNLGQTEVSKVSE 901
                R+ E S         PP +     + +   +    +S      SQ + +T +  V  
Sbjct: 18995 GPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRL 19054

Query: 902   TVQEELTPPPQKAAPQGKS---KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPD 958
             T   E           GKS   +S  +  +   +PP PP     + + + +M++ W+ P 
Sbjct: 19055 TTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPV 19114

Query: 959   KIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAG 1018
               GG+ + GY++ Y+E    +   W +AN   +++   K+S L E ++Y+++V A N+AG
Sbjct: 19115 NDGGSRVIGYHLEYKERSSIL---WSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAG 19171

Query: 1019  LGAPSAVSECFKCEEWTIAVPG-----PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGY 1073
             +G         KC +    VP      PP   + + + + S+ L+W  P + G   +TGY
Sbjct: 19172 IG---------KCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGY 19222

Query: 1074  FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQA-GVGKPSDLAGP 1132
              V+ +E    + +W   N   I+  Y +V  L E   Y FRV A N A  V +PS+  GP
Sbjct: 19223 IVERRELP--DGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGP 19280

Query: 1133  VVAETRPGTKEVVVNVDDDGVISLNF-ECDKMT------PKSEFSWSKDYVSTEDSPRLE 1185
             ++ +       V+++V    VI +   E  K+       P    SW+KD +  E+  R E
Sbjct: 19281 IIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTE 19340

Query: 1186  VESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
             + S  N T +T KD    D G Y   + +  G  S
Sbjct: 19341 IISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRS 19375



 Score =  206 bits (523), Expect = 2e-52
 Identities = 199/804 (24%), Positives = 355/804 (44%), Gaps = 75/804 (9%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P  +W  +G  +   +          + LT  +  + D G Y I V      +  + ++ 
Sbjct: 11043 PTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 11102

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V D    + G P  P+++  L+   +++ ISW+ P  DGGSP++ Y ++K +   D+W  
Sbjct: 11103 VLD----VPGPPTGPINI--LDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 11156

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              +    K  +  +  L +G  Y+FRVRA NK+G+G P   +  V        A+ K  P 
Sbjct: 11157 VSSGSSK-TKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTV--------AKHKFSPP 11207

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
             +P                 PG P    VT+ T +   +SW  P   G   I  Y++E+ E
Sbjct: 11208 SP-----------------PGKPV---VTDITENAATVSWTLPKSDGGSPITGYYMERRE 11247

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
               T  W RVN + P+   +F +  L EG +Y FRV   N AG+ +PS +++       + 
Sbjct: 11248 V-TGKWVRVN-KTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK 11305

Query: 738   IPKAP-GKIIPSRNTDTSVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNP-VKG 793
              P  P    +  ++ +T+ +V W +  S     ++GY +E    G+ +W   N +  ++ 
Sbjct: 11306 PPGPPINPKLKDKSRETADLV-WTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11364

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAI-GGGVSPDVC--PALSDE 850
               F   GL+ G  Y FR++A N  G  E  + +E++  K  +    V  DV     ++  
Sbjct: 11365 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVR 11424

Query: 851   PGGLTASRGRVHEASPP--TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELT 908
              G       RV     P  T+ K+  +  +  +  L    Q+L + E+ ++ E V+ +  
Sbjct: 11425 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL---IQDLPRVEL-QIKEAVRADHG 11480

Query: 909   PPPQKAA-PQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                  A    G ++   +    DR  P P  ++      +++  + W+ P   GG+EIT 
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNVLDR--PGPCQNLKVTNVTKENCTISWENPLDNGGSEITN 11538

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             + V YR+     P +   + V +   +    +NL  N  Y F+V A N  G+G P+  ++
Sbjct: 11539 FIVEYRK-----PNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETK 11592

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW 1087
                     I  PG P +L  ++  K  + L+W+ P + G +P   Y V+ +  K  +D W
Sbjct: 11593 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVE-RRLKGSDD-W 11650

Query: 1088  RGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVN 1147
               +++ +IK  +  V    E   Y FRV+  N+ G    SD         +   ++ V++
Sbjct: 11651 ERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGG---ESDWVKTEEVVVKEDLQKPVLD 11707

Query: 1148  VDDDGVI------SLNFECD-KMTPKSEFSWSKDYVSTE--DSPRLEVESKGNKTKMTFK 1198
             +   GV+      ++  E   +  P  E +W+KD  +T+   SPR++++++ + +K +  
Sbjct: 11708 LKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT 11767

Query: 1199  DLGMDDLGIYSCDVTDTDGIASSY 1222
                  D G Y    T+T G   +Y
Sbjct: 11768 KAKRSDGGKYVVTATNTAGSFVAY 11791



 Score =  204 bits (519), Expect = 6e-52
 Identities = 197/777 (25%), Positives = 323/777 (41%), Gaps = 98/777 (12%)

Query: 474  KEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQP 533
            + D GLY I+V       +    V V D        P  P++    +  K  ++  W+ P
Sbjct: 8276 RPDHGLYMIKVENDHGIAKAPCTVSVLDT-------PGPPINFVFEDIRKTSVLCKWEPP 8328

Query: 534  AVDGGSPILGYFIDKCE-VGTDS-WSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMG 591
              DGGS I+ Y ++K +    DS W     T ++  ++ VT LIEG+ Y+FRVRA N+ G
Sbjct: 8329 LDDGGSEIINYTLEKKDKTKPDSEWIVVTST-LRHCKYSVTKLIEGKEYLFRVRAENRFG 8387

Query: 592  IGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATR 651
             G P  VS+P+ A DP                              P  P    V + T 
Sbjct: 8388 PG-PPCVSKPLVAKDPFGP---------------------------PDAPDKPIVEDVTS 8419

Query: 652  SYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFR 711
            + +++ W  P   G   + Y++EK E  + +W RVN  L + + +  +  L EG +Y FR
Sbjct: 8420 NSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSL-LNALKANVDGLLEGLTYVFR 8478

Query: 712  VRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTS---VVVSWEES--KDAK 766
            V   N+AG G+ S  ++     D +  P  P   IP R TDTS   + + WE        
Sbjct: 8479 VCAENAAGPGKFSPPSDPKTAHDPISPPGPP---IP-RVTDTSSTTIELEWEPPAFNGGG 8534

Query: 767  ELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDS 826
            E+VGY+++  + G+ +W  C    +K  ++T   +  G  Y  RV AVNAAG     +  
Sbjct: 8535 EIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQ 8594

Query: 827  EAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPS 886
                 +      V  DV        GG+    G+       T +  A++  +P    + +
Sbjct: 8595 PVTVAEPQEPPAVELDV-----SVKGGIQIMAGK-------TLRIPAVVTGRPVPTKVWT 8642

Query: 887  SSQ-----------NLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPS 935
              +           N+G      + + ++++       A     SK    + +     P 
Sbjct: 8643 KEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV-PG 8701

Query: 936  PPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEA 995
            P  D+  + + R   +L W  P+  GG+EITG+ +  +   D     WR+     +  E 
Sbjct: 8702 PVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERK---DAKMHTWRQ----PIETER 8754

Query: 996  YK--ISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
             K  I+ L E   Y+F+V A N  G G P  +      +   +  P  P  L  +E  K 
Sbjct: 8755 SKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVD--PLGPPTSPERLTYTERTKS 8812

Query: 1054 SLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVF 1113
            ++ L WK P  +G +P+ GY ++ K    K D +  +N+         V  L E   Y F
Sbjct: 8813 TITLDWKEPRSNGGSPIQGYIIE-KRRHDKPD-FERVNKRLCPTTSFLVENLDEHQMYEF 8870

Query: 1114 RVRAINQAGVGKPSDLAGPVVAETR-PGTKEVVVNVDDDGV-----ISLNFECDKM-TPK 1166
            RV+A+N+ G  +PS     V+ +   P T ++ ++V  D +       ++   D    P 
Sbjct: 8871 RVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM 8930

Query: 1167 SEFSWSKDYVSTE------DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             +  WSK+    E         + EV     KT+++      +D G Y+   ++  G
Sbjct: 8931 PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLG 8987



 Score =  202 bits (515), Expect = 2e-51
 Identities = 243/1051 (23%), Positives = 411/1051 (39%), Gaps = 156/1051 (14%)

Query: 274   LHAPEFIIKP-RSHTVWEK--ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIES 330
             L  PE  +K   SHTV+ +   N+K+   I+G P P+VT  ++ VP+         I   
Sbjct: 19974 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 20033

Query: 331   RYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
                  T+ +      D  +Y  +A N  G   A+ ++VV              G  T P+
Sbjct: 20034 NL---TINLKESVTADAGRYEITAANSSGTTKAFINIVVLD----------RPGPPTGPV 20080

Query: 391   SFG-VTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVP 449
                 +T      ++E     K+D            G +V     +K              
Sbjct: 20081 VISDITEESVTLKWE---PPKYDG-----------GSQVTNYILLKR------------E 20114

Query: 450   LSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIE 507
              S + W +   +  R  +    L   +E  + I+   R G      SA V V+       
Sbjct: 20115 TSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVK-LPYTTP 20173

Query: 508   GAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFA 567
             G P+ P         ++ I + W +P  +GGS ++GY ++  +  +  W + N   ++  
Sbjct: 20174 GPPSTPW---VTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTT 20230

Query: 568   RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIV 627
              F VT +  G  Y FRV A N  G+G PS  SEPV A+D  E                  
Sbjct: 20231 HFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACE------------------ 20272

Query: 628   TEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRV 686
                         PP ++ +T+ +++ V LSW+ P   G   I  Y VE+ +     W + 
Sbjct: 20273 ------------PPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKA 20320

Query: 687   NTELPVKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKAPGKI 745
             +    V   +F +  L +   Y FRV   N+ G +  PSE     VVG    I    G +
Sbjct: 20321 SFT-NVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSE-----VVGPITCIDSYGGPV 20374

Query: 746   IPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQ 805
             I      T VV         K   G  ++     SGK  P             + LV  +
Sbjct: 20375 IDLPLEYTEVV---------KYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE 20425

Query: 806   SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEAS 865
             +    + ++        +     ++++ A+G   S  +   + D+PG      G   E  
Sbjct: 20426 NTT-DLASILIKDADRLNSGCYELKLRNAMGSA-SATIRVQILDKPG----PPGGPIEFK 20479

Query: 866   PPTFQKDALLGSKPNKPSLPS------SSQNLGQTEVSKVSETVQEELTPPPQ------- 912
               T +K  LL   P               +   +   S VSE ++E +    +       
Sbjct: 20480 TVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEY 20539

Query: 913   --------KAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
                     K       +SD +  K     P PP      +  ++SM + W +P   GG++
Sbjct: 20540 IFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSD 20599

Query: 965   ITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSA 1024
             I+GY++  R   D     W +   + + +   K++ L EN  YQ++V A+N AG G  S 
Sbjct: 20600 ISGYFLEKR---DKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSE 20656

Query: 1025  VSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE 1084
              SE +K  +  I  PGPP  ++ ++  K S+ L W  PV+ G + VTGY V++++   +E
Sbjct: 20657 PSEFYKAAD-PIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ--GEE 20713

Query: 1085  DQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKE 1143
             ++W  ++ +  ++     V  LK GV+Y FRV A+N AG G+P ++  PV A+      E
Sbjct: 20714 EEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE 20773

Query: 1144  ----------VVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKT 1193
                       V+    +D  + + F   K  P    +W KD  +     R  +E+  + +
Sbjct: 20774 IDLDVALRTSVIAKAGEDVQVLIPF---KGRPPPTVTWRKDEKNLGSDARYSIENTDSSS 20830

Query: 1194  KMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVE 1253
              +T   +  +D G Y   + +  G   S  +  + L             T     +L V+
Sbjct: 20831 LLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVL------------DTPAACQKLQVK 20878

Query: 1254  ILEKGQVRFWMQAEKLSGNAK-VNYIFNEKE 1283
              + +G V        + G +  +NY+  +++
Sbjct: 20879 HVSRGTVTLLWDPPLIDGGSPIINYVIEKRD 20909



 Score =  202 bits (513), Expect = 3e-51
 Identities = 201/738 (27%), Positives = 302/738 (40%), Gaps = 66/738 (8%)

Query: 438   QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
             +P I W ++G+PL  S++V+   +  + TL+  +  KE  G YT+ +            V
Sbjct: 21095 KPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21154

Query: 498   FVRDADAEIEGAPAAPLD-VKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
                       G P+ P   ++  E   D +I+SW  P  +GG  I  Y I+K E    +W
Sbjct: 21155 ITL-------GPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW 21207

Query: 557   SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSR 616
                  +  +   F V  L++   Y FRVRA N+ G+                        
Sbjct: 21208 KMVCSSVAR-TTFKVPNLVKDAEYQFRVRAENRYGV------------------------ 21242

Query: 617   PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYF-VEK 675
              S P    IIV + +     +PGPP    +   T   + L+W  P   G   +  F VEK
Sbjct: 21243 -SQPLVSSIIVAKHQFR---IPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEK 21298

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
              E  +  WQ+VNT  P+    +    L EG  Y FRV   NSAG+  PS+ ++ T+    
Sbjct: 21299 KERNSILWQKVNTS-PISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSP 21357

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKG 793
             +D P  P  I  +R T   + + W         ++VGY IE    G+ +W  CN   V  
Sbjct: 21358 VDPPGTPDYIDVTRET---ITLKWNPPLRDGGSKIVGYSIEKR-QGNERWVRCNFTDVSE 21413

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAIGGGV---SPDVCPALSD 849
              ++T  GL  G  Y FR+ A NA G +S  SQ S  I  +      +    P+    L  
Sbjct: 21414 CQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLII 21473

Query: 850   EPGGLTASRGRVHEASPP--TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEEL 907
             + G     +  V     P  T+ KD   G +  K      +  LG T +     T     
Sbjct: 21474 KSGESLRIKALVQGRPVPRVTWFKD---GVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21530

Query: 908   TPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                 +     G +K++ +K K    P      I       + M L W  P   G A IT 
Sbjct: 21531 VYTVEAKNASGSAKAE-IKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITH 21589

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             Y +  RE    +     E   +A S  A K+ N  E   YQF+V+A+N  G+G P     
Sbjct: 21590 YIIEKRET-SRLAWALIEDKCEAQSYTAIKLINGNE---YQFRVSAVNKFGVGRPLDSDP 21645

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQW 1087
                  ++T  VP  P   + S +  +S+ L W  P   G + +  Y ++ +E K+   +W
Sbjct: 21646 VVAQIQYT--VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS--TRW 21701

Query: 1088  -RGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE--TRPGTKEV 1144
              + +++  I     KV GL EG  Y F V A N AGVG  S ++  +       P     
Sbjct: 21702 VKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPT 21761

Query: 1145  VVNVDDDGVISLNFECDK 1162
             VV V D    +++ E  K
Sbjct: 21762 VVKVTDTSKTTVSLEWSK 21779



 Score =  201 bits (510), Expect = 6e-51
 Identities = 194/718 (27%), Positives = 295/718 (41%), Gaps = 94/718 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             P++ W    + L  +  V    + +R TLT     + D G Y + +      + +S  V 
Sbjct: 22180 PKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVV 22239

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V      + G    P++V  + A     ++SW +P   GG+ I  Y ++K E GT +W  
Sbjct: 22240 VIGRPGPVTG----PIEVSSVSAES--CVLSWGEPKDGGGTEITNYIVEKRESGTTAWQL 22293

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              N + VK  +  VT L +   Y FRV + N+ G+  P   S P+ A  P           
Sbjct: 22294 VNSS-VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE-SAPIIAEHPF---------- 22341

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                              + P  PT   V   + + + + W+ P   G   I+ Y+VEK E
Sbjct: 22342 -----------------VPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKE 22384

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
               T  W + N ++P     + +  L EG  Y FR    N+AGV + SEA+   +  + +D
Sbjct: 22385 RNTILWVKEN-KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVD 22443

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIE---ASVAGSGKWEPCNNNPVKGS 794
              P  P     +R+T  S++ S        ++VGY IE    S  G G+W  CN   V  +
Sbjct: 22444 APGRPEVTDVTRST-VSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDN 22502

Query: 795   RFTCHGLVTGQSYIFRVRAVNAAG-LSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG 853
              FT   L  G +Y FRV A NAAG +S+ S+ +  +  +         +  P  ++    
Sbjct: 22503 FFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCR--------DEYAPPKAELDAR 22554

Query: 854   LTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQK 913
             L      +   S      DA +G KP     P      G  E+  + E V  + T     
Sbjct: 22555 LHGDLVTIRAGSDLVL--DAAVGGKPE----PKIIWTKGDKELD-LCEKVSLQYTGKRAT 22607

Query: 914   AAPQGKSKSDPLK------------------KKTDRAPPSPPCDITCLESFRDSMVLGWK 955
             A  +   +SD  K                  K  D   P P   +T     ++   L W 
Sbjct: 22608 AVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLD--SPGPCGKLTVSRVTQEKCTLAWS 22665

Query: 956   QPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEE----AYKISNLKENMVYQFQV 1011
              P + GGAEIT Y V  RE            N   V  E    +Y ++ L +N  Y F+V
Sbjct: 22666 LPQEDGGAEITHYIVERRET--------SRLNWVIVEGECPTLSYVVTRLIKNNEYIFRV 22717

Query: 1012  AAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVT 1071
              A+N  G G P           +TI  P PP   +     K+ +++QW  P   G   ++
Sbjct: 22718 RAVNKYGPGVPVESEPIVARNSFTI--PSPPGIPEEVGTGKEHIIIQWTKPESDGGNEIS 22775

Query: 1072  GYFVDLKEAKAKEDQWRGLN-EAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              Y VD +E K+   +W  +N +  + +  LKV  L EG  Y FRV A+N AG  +PS+
Sbjct: 22776 NYLVDKREKKSL--RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 22831



 Score =  191 bits (486), Expect = 4e-48
 Identities = 191/741 (25%), Positives = 302/741 (40%), Gaps = 88/741 (11%)

Query: 412   DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH 471
             DV   R G+T+ +  RV   PE     P+I W + G  L   K V  +    R  L    
Sbjct: 11419 DVITVRVGQTIRILARVKGRPE-----PDITWTKEGKVLVREKRVDLIQDLPRVELQIKE 11473

Query: 472   LNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWK 531
               + D G Y I  +    + Q SA V V D        P    ++K     K+   ISW+
Sbjct: 11474 AVRADHGKYIISAKNSSGHAQGSAIVNVLDR-------PGPCQNLKVTNVTKENCTISWE 11526

Query: 532   QPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMG 591
              P  +GGS I  + ++  +     WS       K  R     L+    Y FRV A NK+G
Sbjct: 11527 NPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTK--RLIKANLLANNEYYFRVCAENKVG 11584

Query: 592   IGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATR 651
             +G       P+ A++P ++                           PG P +L + +  +
Sbjct: 11585 VGPTIETKTPILAINPIDR---------------------------PGEPENLHIADKGK 11617

Query: 652   SYVVLSWKPPG-QRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCF 710
             ++V L W+ P    G   + Y VE+   G+++W+RV+ +  +K   + +    E + Y F
Sbjct: 11618 TFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVH-KGSIKETHYMVDRCVENQIYEF 11676

Query: 711   RVRCSNSAGVGEPSEATEVTVVGD----KLDIPKAPGKIIPSRNT---DTSV------VV 757
             RV+  N  G  +  +  EV V  D     LD+  +    + + +T   +  V       V
Sbjct: 11677 RVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEV 11736

Query: 758   SWEESKDAKELV---GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             +W + KDA +L       I+   A S K+         G ++      T  S++     V
Sbjct: 11737 AWTKDKDATDLTRSPRVKIDTR-ADSSKFSLTKAKRSDGGKYVVTATNTAGSFV-AYATV 11794

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEP--GGLTASRGRVHEASPPTFQKD 872
             N        ++ + ++        VS D C    D P   G    +  + E         
Sbjct: 11795 NVLDKPGPVRNLKIVD--------VSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVW 11846

Query: 873   ALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRA 932
             +   +    P    +    G   + +V    +    PP +      K+K D    K  R 
Sbjct: 11847 STYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYD----KPGR- 11901

Query: 933   PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVS 992
              P PP ++T +   ++ M + W  P+  GG  ITGY++  +E       +W   N  A+ 
Sbjct: 11902 -PDPP-EVTKVS--KEEMTVVWNPPEYDGGKSITGYFLEKKEKHS---TRWVPVNKSAIP 11954

Query: 993   EEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRK 1052
             E   K+ NL  +  YQF+V A N  G+G PS  S     ++  I  PGPP + +  +  K
Sbjct: 11955 ERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKD-PIEPPGPPTNFRVVDTTK 12013

Query: 1053  DSLVLQWKPPVHSGRTPVTGYFVDL--KEAKAKEDQ-WRGLNEAA-IKNVYLKVRGLKEG 1108
              S+ L W  PV+ G  P+ GY V++  K A A  D+ W+  N AA +      V  L E 
Sbjct: 12014 HSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDEN 12073

Query: 1109  VSYVFRVRAINQAGVGKPSDL 1129
               Y FRV A NQ G+G+P++L
Sbjct: 12074 QEYEFRVCAQNQVGIGRPAEL 12094



 Score =  191 bits (484), Expect = 7e-48
 Identities = 185/740 (25%), Positives = 303/740 (40%), Gaps = 88/740 (11%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P+ P +V  L+  K  + +SW +P  DGGS + GY+I++ E  TD W + N T +    +
Sbjct: 23835 PSNPPEV--LDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMY 23892

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGL+    Y FR+ A N +G+   S  SEPV   DP +K                   
Sbjct: 23893 TVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDK------------------- 23933

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNT 688
                     P  P +L +   ++  V L W KP    G E + Y+VE  ++G   W++ N 
Sbjct: 23934 --------PSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNK 23985

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPS 748
             E  +K  +F +  L E   Y FRV   N  G+  P        +  KL   +APG     
Sbjct: 23986 ER-IKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTKLTSGEAPGIRKEM 24042

Query: 749   RNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYI 808
             ++  T +    E ++ + ++VG  +        KW       ++  ++       G+++ 
Sbjct: 24043 KDVTTKL---GEAAQLSCQIVGRPLPDI-----KWYRFGKELIQSRKYKMSS--DGRTHT 24092

Query: 809   FRVRAVNAAGLSEYS----QDSEAIEVKAAIGGGVSPDVCPA--LSDEPGGLTASRGRVH 862
               V          Y+     +   +E  + +    +P   P   L ++  G   S  R+H
Sbjct: 24093 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLH 24152

Query: 863   EA--SPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS 920
                   P        G K     L  +S+N+        +  V + +    Q+    GK 
Sbjct: 24153 VMYIGRPVPAMTWFHGQK-----LLQNSENITIENTEHYTHLVMKNV----QRKTHAGKY 24203

Query: 921   KSDP----------LKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYV 970
             K             L  +    P  P   I      ++S V+ WK P   GG+ IT Y V
Sbjct: 24204 KVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVV 24263

Query: 971   NYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK 1030
                E  +G   +W+  +  A+S    +I NL EN  Y F+V+A N  G+  P  VS    
Sbjct: 24264 EKCEAKEGA--EWQLVS-SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVI 24320

Query: 1031  CEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGL 1090
              +      PG P     + V KDS V+ WKPP   G   +  Y+++ +E   K+++W  +
Sbjct: 24321 IKS-PFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKRE--KKQNKWISV 24377

Query: 1091  NEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET-----RPGTKEVV 1145
                 I+     V+ L EG+ Y FRV+  N  G  + S+++ P+  ++      P  KE +
Sbjct: 24378 TTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEEL 24437

Query: 1146  VNVDDDGVISLNFECDKMT--PKSEFSW---SKDYVSTEDSPRLEVESKGNKTKMTFKDL 1200
              N++     +    C K+T  PK    W    K+ ++     R++ E KG   ++    +
Sbjct: 24438 RNLNVRYQSNATLVC-KVTGHPKPIVKWYRQGKEIIADGLKYRIQ-EFKGGYHQLIIASV 24495

Query: 1201  GMDDLGIYSCDVTDTDGIAS 1220
               DD  +Y    T+  G  S
Sbjct: 24496 TDDDATVYQVRATNQGGSVS 24515



 Score =  189 bits (481), Expect = 1e-47
 Identities = 201/817 (24%), Positives = 331/817 (40%), Gaps = 114/817 (13%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
             PEI W R     +    VQ         L+  + ++ D G Y +++      +  SA+V 
Sbjct: 17557 PEITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSK--SAFVT 17612

Query: 499   VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
             V+  D      P  P ++   E  KD   + W+ P +DGG+ +  Y IDK E    +++ 
Sbjct: 17613 VKVLDT-----PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYAN 17667

Query: 559   CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              +    K + F V  L EG  Y FRV A N+ G+G P    + V A +P           
Sbjct: 17668 VSSKCSKTS-FKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP----------- 17715

Query: 619   APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                                P PP  +++T+ +++   L W+ P   G   ++ Y VE   
Sbjct: 17716 -------------------PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 17756

Query: 678   AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
              GTE W  V      K     +  L+ G+ Y FRV+  N  G  +P     V V+   L 
Sbjct: 17757 KGTEKWSIVAES---KVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP-RVLGVPVIAKDLT 17812

Query: 738   IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGK----WEPCNNNPVKG 793
             I   P   +P          S +  +D K      IE  V G  +    W   +  P+K 
Sbjct: 17813 IQ--PSLKLPFNT------YSIQAGEDLK------IEIPVIGRPRPNISWVK-DGEPLKQ 17857

Query: 794   SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG 853
             +    +   T  S +  ++  N     +Y+       V A    G + +    +  E  G
Sbjct: 17858 TT-RVNVEETATSTVLHIKEGNKDDFGKYT-------VTATNSAGTATENLSVIVLEKPG 17909

Query: 854   LTASRGRVHEAS---------PPTFQKDALLGSK-PNKPSLPSSSQNLGQTEVSKVSETV 903
                   R  E S         PP +     + +    K    +++ ++    V++ +  +
Sbjct: 17910 PPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKI 17969

Query: 904   QEELTPPPQKA---APQGKSKSDPLKKKT-----DRAPPSPPCDITCLESFRDSMVLGWK 955
              +  T    +    A     KS PL  K          P PP         +D M++ W 
Sbjct: 17970 TKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWH 18029

Query: 956   QPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMN 1015
             +P   GG +I GY++  +E    +   W + N   + +  +K + L E + Y+F+V+A N
Sbjct: 18030 EPVNDGGTKIIGYHLEQKEKNSIL---WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAEN 18086

Query: 1016  MAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFV 1075
             + G+G PS VSECF   +     PG P ++    + ++++ L+WK P + G + +TGY V
Sbjct: 18087 IVGIGKPSKVSECFVARD-PCDPPGRPEAI---VITRNNVTLKWKKPAYDGGSKITGYIV 18142

Query: 1076  DLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAG-VGKPSDLAGPVV 1134
             + K+    + +W   +   +      V GL E   Y FRV A N AG   +PSD +G + 
Sbjct: 18143 EKKD--LPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAIT 18200

Query: 1135  AETR---------PGTKEV-VVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTED-SPR 1183
             A            P  K+V VV+  +  V+  +    +  P  +  WSKD    E+ + R
Sbjct: 18201 ARDEIDAPNASLDPKYKDVIVVHAGETFVLEADI---RGKPIPDVVWSKDGKELEETAAR 18257

Query: 1184  LEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIAS 1220
             +E++S   KT +  KD    D G Y   +++  G  S
Sbjct: 18258 MEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18294



 Score =  188 bits (477), Expect = 4e-47
 Identities = 155/528 (29%), Positives = 237/528 (44%), Gaps = 49/528 (9%)

Query: 638   PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
             P PP +L VTE T+  V ++W+PP   G   I  Y VEK EA  +++  V T     S  
Sbjct: 16537 PSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNS-- 16594

Query: 697   FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
             + +  L EG SY FRV   N  G+G P++  +   V +   +P+ PGKI     T  SV 
Sbjct: 16595 WKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE---VPQPPGKITVDDVTRNSVS 16651

Query: 757   VSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             +SW   E     +++ Y +E     S KW  C    VK  +     L  G+ Y+FRV AV
Sbjct: 16652 LSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEYLFRVVAV 16709

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDAL 874
             N  G S+    +  I  K  +   + PDV PA S      +   G+  +   P       
Sbjct: 16710 NEKGRSDPRSLAVPIVAKDLV---IEPDVKPAFSS----YSVQVGQDLKIEVP------- 16755

Query: 875   LGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-------------K 921
             +  +P KP++  +   L   + ++++ T   +LT    K   +                K
Sbjct: 16756 ISGRP-KPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQK 16814

Query: 922   SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPG 981
             +  ++  T   P  P   +   +   +S+ L W  P   GG +IT Y V  R+    V  
Sbjct: 16815 TASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTV-- 16872

Query: 982   KWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGP 1041
              W   +   V+    K++ LK    YQF++ A N    G   A+       ++    PGP
Sbjct: 16873 -WDVVSA-TVARTTLKVTKLKTGTEYQFRIFAENR--YGQSFALESDPIVAQYPYKEPGP 16928

Query: 1042  PHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLK 1101
             P +   + + KDS+V+QW  PV++G +PV GY ++ KE  +    W  +N+  I +   K
Sbjct: 16929 PGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNS--ILWTKVNKTIIHDTQFK 16986

Query: 1102  VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE---TRPGTKEVVV 1146
              + L+EG+ Y FRV A N  GVGK S  +   VA      PGT E ++
Sbjct: 16987 AQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIM 17034



 Score =  179 bits (455), Expect = 2e-44
 Identities = 211/823 (25%), Positives = 315/823 (38%), Gaps = 119/823 (14%)

Query: 439   PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRV--RMGEYYEQYSAY 496
             P++ W + G+     K    L     A L   +  ++D G Y++ +    GE     + +
Sbjct: 12139 PKVTWRKVGIDNVVRKGQVDLVD-TMAFLVIPNSTRDDSGKYSLTLVNPAGEK----AVF 12193

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             V VR  D      P    D+K  +  K    +SW  P  DGGS +  Y ++K E    +W
Sbjct: 12194 VNVRVLDT-----PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW 12248

Query: 557   SQCNDTP-VKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKS 615
             S    TP VK   F VT L+ G  Y FRV AVN+ G G P+ V +PV A DP  +     
Sbjct: 12249 STV--TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE----- 12301

Query: 616   RPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEK 675
                                   P PP  L VTE T++   L+W PP + G   I  ++  
Sbjct: 12302 ----------------------PDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITS 12339

Query: 676   CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
                  +   R      VK     +  L EGK Y FRV   N+ GV  P EA  V    ++
Sbjct: 12340 YREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQ 12399

Query: 736   LDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSG----KWEPCNNNPV 791
             L  PK    ++P + T           K  K+L    IEA V G      KW+   +  V
Sbjct: 12400 LLPPKI---LMPEQIT----------IKAGKKL---RIEAHVYGKPHPTCKWKKGEDEVV 12443

Query: 792   KGSRFTCHGLVTGQSYIFRVRAVNAAGL----SEYSQDSEAIEVKAAIGGGVSPDVCPA- 846
               S    H   +    I +      +G     +E S  ++  ++K  +     P   P  
Sbjct: 12444 TSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFD 12503

Query: 847   LSD--------------EPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLG 892
             +SD              E GG   +   V +           L S   K S        G
Sbjct: 12504 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASV-TKTSCRVGKLIPG 12562

Query: 893   QTEVSKVSET----VQEELTPPPQKAA-PQGKSKSDPLKKKTDRAPPSPPCDITCLESFR 947
             Q  + +V       + E LT P   A  P G               PS P +    +  +
Sbjct: 12563 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGV--------------PSEPKNARVTKVNK 12608

Query: 948   DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY 1007
             D + + W +PD  GG+ I GY +  +E    +   W +AN   V    Y  + L E + Y
Sbjct: 12609 DCIFVAWDRPDSDGGSPIIGYLIERKERNSLL---WVKANDTLVRSTEYPCAGLVEGLEY 12665

Query: 1008  QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 1067
              F++ A+N AG   PS  +E +      +  PG P  +   +V K ++ L W  P H G 
Sbjct: 12666 SFRIYALNKAGSSPPSKPTE-YVTARMPVDPPGKPEVI---DVTKSTVSLIWARPKHDGG 12721

Query: 1068  TPVTGYFVDLKEAKAKEDQWRGLNEAA--IKNVYLKVRGLKEGVSYVFRVRAINQAGVGK 1125
             + + GYFV+    K   D+W   N A   I        GL+E   Y FR  A     +  
Sbjct: 12722 SKIIGYFVEA--CKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISP 12779

Query: 1126  PSDLAGPV--VAETRPGTKEVVVNVDDDGVISLNFE-CDKMT----PKSEFSWSKDYVST 1178
             PS+ + PV  +AE  P   ++ V +     +      C   T    P    SW KD    
Sbjct: 12780 PSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLL 12839

Query: 1179  EDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
             + +  +++  + N   +    +   D G Y+    ++ G  S+
Sbjct: 12840 KPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSA 12882



 Score =  177 bits (450), Expect = 6e-44
 Identities = 186/778 (23%), Positives = 306/778 (39%), Gaps = 86/778 (11%)

Query: 465   ATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKD 524
             +TLT  + N+ D G YT+ V      +  +  V V D        P  P+  K  +  + 
Sbjct: 21914 STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPG-----PPGPITFK--DVTRG 21966

Query: 525   YIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRV 584
                + W  P +DGG+ I  Y ++K E    SW   ++   +   F V  L EG  Y FRV
Sbjct: 21967 SATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQI-FKVNDLAEGVPYYFRV 22025

Query: 585   RAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDL 644
              AVN+ G+G P  + EP+ A                       TE+       P PP  L
Sbjct: 22026 SAVNEYGVGEPYEMPEPIVA-----------------------TEQ-------PAPPRRL 22055

Query: 645   SVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLA 703
              V + ++S  VL+W  P   G   I  Y +E  + G++ W         K   F +  L 
Sbjct: 22056 DVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH---TKQLTFTVERLV 22112

Query: 704   EGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK-----LDIPKAPGKIIPSRNTDTSVVVS 758
             E   Y FRV+  N AG  EP EA    ++ +       D+     ++I  +      +  
Sbjct: 22113 EKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDV 22172

Query: 759   WEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAG 818
                 + A ++     E  +  + +           +  T    + G S  + +   N AG
Sbjct: 22173 PISGRPAPKVTWKLEEMRLKETDRVSITTTKD--RTTLTVKDSMRGDSGRYFLTLENTAG 22230

Query: 819   LSEYSQDSEAIEVKAAIGG-----GVSPDVCPALSDEP--GGLTASRGRVHEASPPTFQK 871
             +  +S     I     + G      VS + C     EP  GG T     + E        
Sbjct: 22231 VKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRE----- 22285

Query: 872   DALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-KSDPLKKKTD 930
                  S      L +SS    Q +V+ +++ ++       +      K  +S P+  +  
Sbjct: 22286 -----SGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHP 22340

Query: 931   RAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKA 990
               PPS P          ++M + W++P   GG++I GY+V  +E    +   W + N   
Sbjct: 22341 FVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTIL---WVKENKVP 22397

Query: 991   VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEV 1050
               E  YK++ L E + YQF+  A+N AG+   S  S     +   +  PG P   + ++V
Sbjct: 22398 CLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQN-PVDAPGRP---EVTDV 22453

Query: 1051  RKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKED-QWRGLNEAAIKNVYLKVRGLKEGV 1109
              + ++ L W  P + G + V GY ++ K      D +W   N   + + +  V  L EG 
Sbjct: 22454 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22513

Query: 1110  SYVFRVRAINQAGV-GKPSDLAGPVVA--ETRPGTKEVVVNVDDDGVISLNFECDKM--- 1163
             +Y FRV A N AGV  K S+  GPV    E  P   E+   +  D ++++    D +   
Sbjct: 22514 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGD-LVTIRAGSDLVLDA 22572

Query: 1164  ----TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
                  P+ +  W+K     +   ++ ++  G +     K     D G Y+  V +  G
Sbjct: 22573 AVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22630



 Score =  167 bits (422), Expect = 1e-40
 Identities = 156/528 (29%), Positives = 237/528 (44%), Gaps = 54/528 (10%)

Query: 637  VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFV-EKCEAGTENWQRVNTELPVKSP 695
            VPGP  DL      R   +L+W  P   G   I  F+ E+ +A    W++     P+++ 
Sbjct: 8699 VPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ-----PIETE 8753

Query: 696  RFA--LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDT 753
            R    +  L EG+ Y FRV   N  G G P E   +  V D L  P +P ++  +  T +
Sbjct: 8754 RSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAV-DPLGPPTSPERLTYTERTKS 8812

Query: 754  SVVVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRV 811
            ++ + W+E  S     + GY IE        +E  N      + F    L   Q Y FRV
Sbjct: 8813 TITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRV 8872

Query: 812  RAVNAAGLSEYS-------QDSEA---IEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV 861
            +AVN  G SE S       QD E    I+++ ++ G    D     + EP  + A    V
Sbjct: 8873 KAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG----DTIKVKAGEPVHIPAD---V 8925

Query: 862  HEASPPTFQ--KDALLGSKPNKP---SLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAP 916
                 P  +  K+  +  KP      +    S++  +TE+S      +++ T     +  
Sbjct: 8926 TGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNR 8985

Query: 917  QGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVI 976
             G    +   +  DR  PSPP ++   +   +S  L W  P   GG+EIT Y ++ R+  
Sbjct: 8986 LGSVFRNVHVEVYDR--PSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDA- 9042

Query: 977  DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
                 +W E    AV E+ Y I  L  N  Y+F+V A+N  G+       EC K ++  I
Sbjct: 9043 SRKKAEWEEVTNTAV-EKRYGIWKLIPNGQYEFRVRAVNKYGIS-----DEC-KSDKVVI 9095

Query: 1037 A----VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNE 1092
                 +PGPP   K     K S+++ W PP+ +G +P+TGY+++ +E  +    W  ++ 
Sbjct: 9096 QDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSP--YWSRVSR 9153

Query: 1093 AAIKNVYLK-----VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA 1135
            A I  V LK     V  L EGV Y FR  AIN AG+G PS+ + P VA
Sbjct: 9154 APITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVA 9201



 Score =  157 bits (397), Expect = 8e-38
 Identities = 201/762 (26%), Positives = 300/762 (39%), Gaps = 125/762 (16%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESR-YGM------HTLEINGCDF 344
             E  +L C I G P P + WY+           GK +I+SR Y M      HTL +   + 
Sbjct: 24051 EAAQLSCQIVGRPLPDIKWYRF----------GKELIQSRKYKMSSDGRTHTLTVMTEEQ 24100

Query: 345   EDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFE 404
             ED   Y   A N  GE+   + ++++         +FH G    PL              
Sbjct: 24101 EDEGVYTCIATNEVGEVETSSKLLLQA------TPQFHPG---YPLK------------- 24138

Query: 405   IHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGER 464
                 +K+   +G  G T+ L    +  P      P + W+     L  S+ + T+ + E 
Sbjct: 24139 ----EKY---YGAVGSTLRLHVMYIGRPV-----PAMTWFHGQKLLQNSENI-TIENTEH 24185

Query: 465   AT-LTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDA--DAEIEGAPAAPLDVKCLEA 521
              T L   ++ +        +   G+Y  Q S      DA  D EI+  P  P     +EA
Sbjct: 24186 YTHLVMKNVQR--------KTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEA 24237

Query: 522   N-KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSY 580
               K+  +ISWK PA DGGS I  Y ++KCE    +  Q   + +      +  L E   Y
Sbjct: 24238 LLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGY 24297

Query: 581   IFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGP 640
              FRV A N  GI  P  VS  V    P EK                           PG 
Sbjct: 24298 YFRVSAQNTFGISDPLEVSSVVIIKSPFEK---------------------------PGA 24330

Query: 641   PTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFAL 699
             P   ++T  T+   V++WKPP   G   I  Y++EK E     W  V TE  ++   F++
Sbjct: 24331 PGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTE-EIRETVFSV 24389

Query: 700   FDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP-KAPGKIIPSRNTD----TS 754
              +L EG  Y FRV+C N  G  E SE +E   +  K D+P +AP      RN +    ++
Sbjct: 24390 KNLIEGLEYEFRVKCENLGGESEWSEISE--PITPKSDVPIQAPHFKEELRNLNVRYQSN 24447

Query: 755   VVVSWEESKDAKELVGYYIEAS--VAGSGKWEPCNNNPVKGS--RFTCHGLVTGQSYIFR 810
               +  + +   K +V +Y +    +A   K+        KG   +     +    + +++
Sbjct: 24448 ATLVCKVTGHPKPIVKWYRQGKEIIADGLKY---RIQEFKGGYHQLIIASVTDDDATVYQ 24504

Query: 811   VRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQ 870
             VRA N  G S     S  +EV A I         P   +  G + A RG V     P   
Sbjct: 24505 VRATNQGG-SVSGTASLEVEVPAKIH-------LPKTLEGMGAVHALRGEVVSIKIPFSG 24556

Query: 871   K-DALLGSKPNKPSLPSSSQN---LGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLK 926
             K D ++  +  +  + ++      + ++  S V     E           + +   D   
Sbjct: 24557 KPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKT 24616

Query: 927   KKTDRAP-PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWRE 985
              + D A  P PP  +   +  RDS+ L W +P   GG++IT Y V   E       +W  
Sbjct: 24617 VELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV---EKCATTAERW-- 24671

Query: 986   ANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
               V    E  Y + NL     YQF+V A N  GL  PS  SE
Sbjct: 24672 LRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSE 24713



 Score =  153 bits (387), Expect = 1e-36
 Identities = 143/539 (26%), Positives = 230/539 (42%), Gaps = 61/539 (11%)

Query: 637  VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFV-EKCEAGTENWQRVNTELPVKSP 695
            +PGP  D+  ++ T+S   L+W+PP   G   I+++V E+ EAG        T +PV S 
Sbjct: 7982 LPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRR------TYIPVMSG 8035

Query: 696  R----FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNT 751
                 + + DL     Y FRV+  N  G GE  E     +  D    P  P  +     T
Sbjct: 8036 ENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPT 8095

Query: 752  DTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIF 809
              ++ ++W+        +++GY IE    G  +W+ CN + V    +T  GL  G+ Y F
Sbjct: 8096 AEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQF 8155

Query: 810  RVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVC--PALSDEPGGLTASRGRVHEASPP 867
            RVRA NAAG+SE    S A     A+    +P V    +L  + G   A    +  +  P
Sbjct: 8156 RVRAENAAGISE---PSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYP 8212

Query: 868  TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEE---LTPPPQKAAPQGKSKSDP 924
            T     +   K     +P   +      V +    VQEE   + P  Q+ +     K + 
Sbjct: 8213 T-----ITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 8267

Query: 925  ----------------LKKKTDRAPPSPPCDITCLES--------FRD----SMVLGWKQ 956
                            +K + D      PC ++ L++        F D    S++  W+ 
Sbjct: 8268 QLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEP 8327

Query: 957  PDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNM 1016
            P   GG+EI  Y +  ++     P          +    Y ++ L E   Y F+V A N 
Sbjct: 8328 PLDDGGSEIINYTLEKKDKTK--PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8385

Query: 1017 AGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVD 1076
             G G P  VS+    ++     P  P      +V  +S++++W  P  +G +P+ GY+++
Sbjct: 8386 FGPG-PPCVSKPLVAKD-PFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNG-SPILGYWLE 8442

Query: 1077 LKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA 1135
             +E  +    W  +N++ +  +   V GL EG++YVFRV A N AG GK S  + P  A
Sbjct: 8443 KREVNS--THWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTA 8499



 Score =  153 bits (386), Expect = 2e-36
 Identities = 113/372 (30%), Positives = 180/372 (48%), Gaps = 30/372 (8%)

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
             +S P+       PP PP         +DSMV+ W +P   GG EI GY +  R+  +GV 
Sbjct: 18392 ESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDK-EGV- 18449

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
              +W + N K +++   +++ L E   Y+F+VAA N AG+G PS  S  ++  +  +  PG
Sbjct: 18450 -RWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD-ALYPPG 18507

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVY 1099
             PP + K ++  + S+ L W  P++ G  PV GY V++KEA A  D+W        ++   
Sbjct: 18508 PPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAA--DEWTTCTPPTGLQGKQ 18565

Query: 1100  LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN-- 1157
               V  LKE   Y FR+ AIN  GVG+P+ L G VVA+ R    E+ ++ D   V+ L   
Sbjct: 18566 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRAS 18625

Query: 1158  -----FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
                  F   K  P+ E  W K      D  ++EV S  + T +   ++   D G Y+  +
Sbjct: 18626 ATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLVIDNVTRFDSGRYNLTL 18683

Query: 1213  TDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGN 1272
              +  G  ++++       R+L        P+ PV   L +  ++K  V    +   + G 
Sbjct: 18684 ENNSGSKTAFV-----NVRVL------DSPSAPV--NLTIREVKKDSVTLSWEPPLIDGG 18730

Query: 1273  AKV-NYIFNEKE 1283
             AK+ NYI  ++E
Sbjct: 18731 AKITNYIVEKRE 18742



 Score =  152 bits (385), Expect = 2e-36
 Identities = 165/617 (26%), Positives = 249/617 (40%), Gaps = 104/617 (16%)

Query: 478  GLYTIRVRMGEYY----EQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQP 533
            G Y  RVR    Y    E  S  V ++D    + G P  P   K L   K  +++SW  P
Sbjct: 9070 GQYEFRVRAVNKYGISDECKSDKVVIQDP-YRLPGPPGKP---KVLARTKGSMLVSWTPP 9125

Query: 534  AVDGGSPILGYFIDKCEVGTDSWSQCNDTPV-----KFARFPVTGLIEGRSYIFRVRAVN 588
              +GGSPI GY+++K E G+  WS+ +  P+     K   F V  L+EG  Y FR  A+N
Sbjct: 9126 LDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 9185

Query: 589  KMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTE 648
              GIG PS  S+P  A DP                              PGPP+   V +
Sbjct: 9186 AAGIGPPSEPSDPEVAGDPI---------------------------FPPGPPSCPEVKD 9218

Query: 649  ATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT-ELPVKSPRFALFDLAEGK 706
             T+S + L WKPP + G   I  Y VE  E GT +W+RVN  +  + +    + +L E +
Sbjct: 9219 KTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELR 9278

Query: 707  SYCFRVRCSNSAGVGEPSEATE-----------------------VTVVGDKLDIPKAPG 743
             Y FRV+  N AG  EPS+ T                        V   G ++ IP    
Sbjct: 9279 KYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPA--- 9335

Query: 744  KIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVT 803
             +I  R T  S   SWE    AK+ +   +   +    + E   N+ V      C    T
Sbjct: 9336 -VIKGRPTPKS---SWEFDGKAKKAMKDGVH-DIPEDAQLETAENSSVIIIP-ECKRSHT 9389

Query: 804  GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHE 863
            G+   + + A N AG     Q +    VK     G   D+   +SD    +T    R+  
Sbjct: 9390 GK---YSITAKNKAG-----QKTANCRVKVMDVPGPPKDL--KVSD----ITRGSCRLSW 9435

Query: 864  ASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKS- 922
              P     D + G    K ++   +      +    +  V + L+        + +++  
Sbjct: 9436 KMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFG 9495

Query: 923  -----DPLKKKTDRAP---PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYR- 973
                 + +++ T R P   P PP  +      ++++ L WK P   GG+ +T Y V    
Sbjct: 9496 IGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLA 9555

Query: 974  -EVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCE 1032
             +        WR+ N + V E  + + +L E   Y+F+V A+N AG+  PSA      C+
Sbjct: 9556 WDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQ 9615

Query: 1033 EWTIAVPGPPHSLKCSE 1049
                  P  P S+   E
Sbjct: 9616 R-----PDMPPSIDLKE 9627



 Score =  150 bits (380), Expect = 8e-36
 Identities = 169/756 (22%), Positives = 290/756 (38%), Gaps = 92/756 (12%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             T+    +++L  S++G P P +TW K  + +   A     II++      L ++  +  D
Sbjct: 22960 TIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA-----IIDTTESYSLLIVDKVNRYD 23014

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRF-HAGASTMPLSFGVTPYGYASRFEI 405
               +Y   A N  G+ SA   V V    G     +       ++ +++ +      +    
Sbjct: 23015 AGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNN 23074

Query: 406   HFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERA 465
             +  +K + +  R  +T++  C   +             YR          +  L  G   
Sbjct: 23075 YIVEKREAAM-RAFKTVTTKCSKTL-------------YR----------ISGLVEG--- 23107

Query: 466   TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDY 525
               T  +     E +Y I    GE  E   A +        +   P  P  ++ ++  K  
Sbjct: 23108 --TMYYFRVLPENIYGI----GEPCETSDAVL--------VSEVPLVPAKLEVVDVTKST 23153

Query: 526   IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
             + ++W++P  DGGS + GY ++ C+ GT+ W +            VT L EG  Y+FR+R
Sbjct: 23154 VTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23213

Query: 586   AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
             A N+ G+  P      V   D      L+  P+       + T  + +  +  G P +L 
Sbjct: 23214 AQNEKGVSEPRETVTAVTVQD------LRVLPTID-----LSTMPQKTIHVPAGRPVELV 23262

Query: 646   VTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEG 705
             +  A R     SW   G +  E                +RV  E   K  +  + +    
Sbjct: 23263 IPIAGRPPPAASWFFAGSKLRES---------------ERVTVETHTKVAKLTIRETTIR 23307

Query: 706   KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESK 763
              +  + +   N  G    SE  +V ++ DK   P  P KI       TS+ +SWE  E  
Sbjct: 23308 DTGEYTLELKNVTGT--TSETIKVIIL-DKPGPPTGPIKI--DEIDATSITISWEPPELD 23362

Query: 764   DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823
                 L GY +E   A    W P + + V  S F    L  G  Y+FRV A N  G+  Y 
Sbjct: 23363 GGAPLSGYVVEQRDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYL 23421

Query: 824   QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTAS------RGRVHEASPPTFQKDALLGS 877
             Q SE IE +++I     P+          G+T +       G          +K+     
Sbjct: 23422 Q-SEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADR 23480

Query: 878   KPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPP 937
                   +P +      T +++  E  +  +T    + + +    S P+      APP  P
Sbjct: 23481 WVRVNKVPVTMTRYRSTGLTEGLE-YEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKP 23539

Query: 938   CDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYK 997
              +    ++ R S+ L W  P+  GG+++TGY +  ++V      +W + N        Y 
Sbjct: 23540 QNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQ---HEWTKCNTTPTKIREYT 23596

Query: 998   ISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE 1033
             +++L +   Y+F+V A N  G G P+ V    K  E
Sbjct: 23597 LTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTE 23632



 Score =  145 bits (366), Expect = 3e-34
 Identities = 132/461 (28%), Positives = 195/461 (42%), Gaps = 55/461 (11%)

Query: 367   VVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKF-DVSFGREGETMSLG 425
             V+ +   G F E    +GA        +T            D K+ DV     GET  L 
Sbjct: 18180 VIARNAAGNFSEPSDSSGA--------ITARDEIDAPNASLDPKYKDVIVVHAGETFVLE 18231

Query: 426   CRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG-ERATLTFSHLNKEDEGLYTIRV 484
               +   P      P++ W ++G  L  +     + S  ++ TL      + D G Y +++
Sbjct: 18232 ADIRGKPI-----PDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKL 18286

Query: 485   RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGY 544
                   +     V V D      G P  PL V  + A K Y+  +W  P  DGG+ I  Y
Sbjct: 18287 SNVGGTKSIPITVKVLDRP----GPPEGPLKVTGVTAEKCYL--AWNPPLQDGGANISHY 18340

Query: 545   FIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAA 604
              I+K E    SW+Q + T V+   + VT L+ G  YIFRV AVNK GIG P   S PV A
Sbjct: 18341 IIEKRETSRLSWTQVS-TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE-SGPVTA 18398

Query: 605   LDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSW-KPPGQ 663
              +P +                            PGPP+   V+  T+  +V++W +P   
Sbjct: 18399 CNPYKP---------------------------PGPPSTPEVSAITKDSMVVTWARPVDD 18431

Query: 664   RGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEP 723
              G E   Y +EK +     W + N +  +   R  +  L EG SY FRV   N+AGVGEP
Sbjct: 18432 GGTEIEGYILEKRDKEGVRWTKCNKKT-LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEP 18490

Query: 724   SEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSG 781
             SE +      D L  P  P     +  + +SV ++W +        + GY +E   A + 
Sbjct: 18491 SEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAAD 18550

Query: 782   KWEPCN-NNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSE 821
             +W  C     ++G +FT   L     Y FR+ A+N+ G+ E
Sbjct: 18551 EWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGE 18591



 Score =  145 bits (365), Expect = 4e-34
 Identities = 179/719 (24%), Positives = 290/719 (40%), Gaps = 83/719 (11%)

Query: 638  PGPPTDLSVTEATRSYVVLSWKPP-GQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPR 696
            PGPP +    +  ++ V+  W+PP    G E I Y +EK +    + + +     ++  +
Sbjct: 8305 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCK 8364

Query: 697  FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
            +++  L EGK Y FRVR  N  G G P   ++  V  D    P AP K I    T  S++
Sbjct: 8365 YSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAPDKPIVEDVTSNSML 8423

Query: 757  VSWEESKD-AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVN 815
            V W E KD    ++GY++E     S  W   N + +   +    GL+ G +Y+FRV A N
Sbjct: 8424 VKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAEN 8483

Query: 816  AAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDA-L 874
            AAG  ++S  S+       I     P   P ++D     T+S     E  PP F     +
Sbjct: 8484 AAGPGKFSPPSDPKTAHDPISPPGPP--IPRVTD-----TSSTTIELEWEPPAFNGGGEI 8536

Query: 875  LGSKPNKPSLPSSSQN--------LGQTEVSKVSETVQEELTPPPQKAAPQGK-SKSDPL 925
            +G   +K  + ++  +        + Q  V ++ E    +L      AA +G   ++ P+
Sbjct: 8537 VGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPV 8596

Query: 926  KKKTDRAPPSPPCDITCLESFR---------DSMVLGWKQPDKIGGAEITGYYVNYREVI 976
                 + PP+   D++     +          ++V G   P K+   E  G     R VI
Sbjct: 8597 TVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKE-EGELDKDRVVI 8655

Query: 977  DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
            D         NV   SE   K +  K++  Y   + A N  G    +A  E F       
Sbjct: 8656 D---------NVGTKSELIIKDALRKDHGRYV--ITATNSCGSKFAAARVEVFD------ 8698

Query: 1037 AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIK 1096
             VPGP   LK     +   +L W  P   G + +TG+ ++ K+AK     WR   E   +
Sbjct: 8699 -VPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKM--HTWRQPIET--E 8753

Query: 1097 NVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG----TKEVVVNVDDDG 1152
                 + GL EG  Y FRV A N+ G G P ++ GP++A    G     + +        
Sbjct: 8754 RSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEI-GPILAVDPLGPPTSPERLTYTERTKS 8812

Query: 1153 VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
             I+L+++  +    S            D P  E  +K      +F    +D+  +Y   V
Sbjct: 8813 TITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRV 8872

Query: 1213 TDTDGIASS-------YLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQ 1265
               + I  S        +I ++E+   + L    +  T+ VK+   V I           
Sbjct: 8873 KAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHI----------- 8921

Query: 1266 AEKLSG--NAKVNYIFNEKEIFEGPK-----YKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
               ++G    K+ +  NE  + E P       K  + R+    E+ + K   ED+GTYT
Sbjct: 8922 PADVTGLPMPKIEWSKNE-TVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYT 8979



 Score =  139 bits (351), Expect = 2e-32
 Identities = 139/561 (24%), Positives = 228/561 (40%), Gaps = 59/561 (10%)

Query: 510  PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
            P  P+DV+      + + I+WK P  DGGS I+GY I+K   G + W +CN+  V    +
Sbjct: 8083 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8142

Query: 570  PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
               GL EG+ Y FRVRA N  GI  PSR + P  A+DP +  ++  R S     ++   +
Sbjct: 8143 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSL----EVKRGD 8198

Query: 630  EEPSEGIVPGPP-------TDLSV---TEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAG 679
            E   +  + G P        D +V    E  +    L  +  G+   E            
Sbjct: 8199 EIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLS 8258

Query: 680  TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 739
             +N ++  ++L V+       D        + ++  N  G+ +      V      LD P
Sbjct: 8259 IDNSKKGESQLRVR-------DSLRPDHGLYMIKVENDHGIAKAPCTVSV------LDTP 8305

Query: 740  KAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEA--SVAGSGKWEPCNNNPVKGSR 795
              P   +      TSV+  WE   D    E++ Y +E         +W    +  ++  +
Sbjct: 8306 GPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTST-LRHCK 8364

Query: 796  FTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLT 855
            ++   L+ G+ Y+FRVRA N  G       S+ +  K   G   +PD  P + D      
Sbjct: 8365 YSVTKLIEGKEYLFRVRAENRFGPGPPCV-SKPLVAKDPFGPPDAPDK-PIVED-----V 8417

Query: 856  ASRGRVHEASPPTFQKDALLGSKPNKPSLPS--------SSQNLGQTEVSKVSETVQEEL 907
             S   + + + P      +LG    K  + S        S  N  +  V  + E +    
Sbjct: 8418 TSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVF 8477

Query: 908  TPPPQKAAPQGK--SKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEI 965
                + AA  GK    SDP       +PP PP      ++   ++ L W+ P   GG EI
Sbjct: 8478 RVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEI 8536

Query: 966  TGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAV 1025
             GY+V+ + V      +W     K +    Y +  ++E   Y+ +V+A+N AG G P   
Sbjct: 8537 VGYFVDKQLV---GTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPG-- 8591

Query: 1026 SECFKCEEWTIAVPGPPHSLK 1046
                + +  T+A P  P +++
Sbjct: 8592 ----ETQPVTVAEPQEPPAVE 8608



 Score =  134 bits (337), Expect = 7e-31
 Identities = 227/973 (23%), Positives = 378/973 (38%), Gaps = 127/973 (13%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFI-----DKCEVGTDSWSQCNDTPV 564
             P  P+ +K     K+ + +SWK P  DGGSP+  Y +     D      ++W QCN   V
Sbjct: 9515  PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDV 9574

Query: 565   KFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQ 624
             +  +F V  L+EG  Y FRV+AVN  G      VS+P A + P +  R    PS     +
Sbjct: 9575  EELQFTVEDLVEGGEYEFRVKAVNAAG------VSKPSATVGPCDCQRPDMPPSID-LKE 9627

Query: 625   IIVTEEEPSEGIV---PGPPTDLSVTEATRSYVVLSW-KPPGQR--GHEGIMYFVEKCEA 678
              +  EE  +  IV    G P           +  L+W K P ++    E ++Y       
Sbjct: 9628  FMEVEEGTNVNIVAKIKGVP-----------FPTLTWFKAPPKKPDNKEPVLYDT----- 9671

Query: 679   GTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDI 738
                    VN  +   +    +       +  + +   N+  +G  S+   + V+G +   
Sbjct: 9672  ------HVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNN--LGTASKEMRLNVLG-RPGP 9722

Query: 739   PKAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRF 796
             P  P K   S + D  + +SW   KD    ++  Y IE   A    W   ++ P K   +
Sbjct: 9723  PVGPIK-FESVSAD-QMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP-KECTY 9779

Query: 797   TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTA 856
             T   L+ G  Y+FR+ A N  G+ E   DSE    +       +PD     S     +T 
Sbjct: 9780  TIPKLLEGHEYVFRIMAQNKYGIGE-PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTV 9838

Query: 857   S--RGRVHEASPPT----FQKDALLGSKPNKPSLPSSSQNLGQT-EVSKVSETVQEELTP 909
             +         SP T      KD            P  +  LG + +V+ + E    +   
Sbjct: 9839  NWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRV 9898

Query: 910   PPQKAAPQGKSK--SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                 AA  G +   SDP   +   APP PP      +  + S  L W  P K GG+++TG
Sbjct: 9899  YAINAAGVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTG 9957

Query: 968   YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             Y V Y+E  +G   +W +   K V      ++ LKE   Y+F+V A+N+AG+G P  V++
Sbjct: 9958  YIVEYKE--EG-KEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD 10014

Query: 1028  CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVH-----SGRTPVTGYFVDLKEAKA 1082
               + ++  ++   P   L  S   +D +V+     +      SG+ P T   V     + 
Sbjct: 10015 VIEMKDRLVS---PDLQLDASV--RDRIVVHAGGVIRIIAYVSGKPPPT---VTWNMNER 10066

Query: 1083  KEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS------DLAGPVVAE 1136
                Q   +   AI +  + ++  +     V+ + A N+AG  K +      D+ GPV   
Sbjct: 10067 TLPQEATIETTAISS-SMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPV--- 10122

Query: 1137  TRPGTKEVVVNVDDDGVISLNF--ECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTK 1194
                GT  +  N+ ++      F  E D  +P + +   K     E   R         T+
Sbjct: 10123 ---GTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEK----RESDRRAWTPVTYTVTR 10175

Query: 1195  MTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEI 1254
                   G+     Y   +   + I     ++  E    L +      P  P   +L V+ 
Sbjct: 10176 QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSE---ALVIREPITVPERP--EDLEVKE 10230

Query: 1255  LEKGQVRFWMQAEKLSGNAK-VNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDE 1313
             + K  V       K  G ++ +NY+   + I      K H   N  ++         ++ 
Sbjct: 10231 VTKNTVTLTWNPPKYDGGSEIINYVLESRLI---GTEKFHKVTNDNLLSRKYTVKGLKEG 10287

Query: 1314  GTYTFQLQ------DGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWE 1367
              TY +++        GK +  +  +   D         +F+ +  IR  G  F       
Sbjct: 10288 DTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIR-VGEAFA------ 10340

Query: 1368  VTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKK--DAGI 1425
             +TG  +   K KV+         W+KDE ++  D++   K    TL + +   K  D+G 
Sbjct: 10341 LTGRYSGKPKPKVS---------WFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGK 10391

Query: 1426  YEVILKDDRGKDK 1438
             Y V++++  G  K
Sbjct: 10392 YCVVVENSTGSRK 10404



 Score =  131 bits (330), Expect = 5e-30
 Identities = 219/1039 (21%), Positives = 387/1039 (37%), Gaps = 164/1039 (15%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             T+    ++ L  ++ G PEP++ W K    +++     K  ++      T  I  CD  D
Sbjct: 22561 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCE---KVSLQYTGKRATAVIKFCDRSD 22617

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYK-----GEFDETRFHAGASTMPLSFGVTPYGYAS 401
             + +Y  +  N  G  +   SV+VK        G+   +R      T+  S      G   
Sbjct: 22618 SGKYTLTVKNASG--TKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGG--- 22672

Query: 402   RFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS 461
                                            EI H+  E +        S   WV  +  
Sbjct: 22673 ------------------------------AEITHYIVERR------ETSRLNWV--IVE 22694

Query: 462   GERATLTF--SHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVK 517
             GE  TL++  + L K +E ++ +R   + G      S  +  R++   I   P  P +V 
Sbjct: 22695 GECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNS-FTIPSPPGIPEEV- 22752

Query: 518   CLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCN-DTPVKFARFPVTGLIE 576
                  K++III W +P  DGG+ I  Y +DK E  +  W++ N D  V   R  VT L+E
Sbjct: 22753 --GTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLME 22810

Query: 577   GRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGI 636
             G  Y FRV AVN  G   PS  S  ++  +P+                            
Sbjct: 22811 GCDYQFRVTAVNAAGNSEPSEASNFISCREPS---------------------------Y 22843

Query: 637   VPGPPTDLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSP 695
              PGPP+   V + T+  + L+W KP    G + + Y +E  E  T+ W RV+T   +++ 
Sbjct: 22844 TPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 22903

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
              F + DL  G+ Y FRV   N  G+ E SE+       ++++IP                
Sbjct: 22904 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP---------------- 22947

Query: 756   VVSWEESKDAKELV----GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLV-TGQSY-IF 809
                 E + D K+ V    G  +   V+ SG+  P      +G       ++ T +SY + 
Sbjct: 22948 --DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLL 23005

Query: 810   RVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGR--VHEASPP 867
              V  VN     +Y+ ++E         G  S  V   + D PG   + + +    ++   
Sbjct: 23006 IVDKVNRYDAGKYTIEAE------NQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTI 23059

Query: 868   TFQKDALLGSKPNKPSL---PSSSQNLGQTEVSKVSETVQE-----ELTPPPQKAAPQGK 919
             T++   + G  P    +     ++    +T  +K S+T+       E T    +  P+  
Sbjct: 23060 TWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENI 23119

Query: 920   SKSDPLKKKTDRA----PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREV 975
                    + +D       P  P  +  ++  + ++ L W++P   GG+ +TGY +   E 
Sbjct: 23120 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVL---EA 23176

Query: 976   IDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWT 1035
                   +W +      +   + +++L E   Y F++ A N  G+  P         ++  
Sbjct: 23177 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23236

Query: 1036  I-----AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGL 1090
             +         P  ++     R   LV+    P+     P   +F     +K +E + R  
Sbjct: 23237 VLPTIDLSTMPQKTIHVPAGRPVELVI----PIAGRPPPAASWF--FAGSKLRESE-RVT 23289

Query: 1091  NEAAIKNVYLKVR--GLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNV 1148
              E   K   L +R   +++   Y   ++ +     G  S+    ++ + +PG     + +
Sbjct: 23290 VETHTKVAKLTIRETTIRDTGEYTLELKNV----TGTTSETIKVIILD-KPGPPTGPIKI 23344

Query: 1149  DDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPR---LEVESKGNKTKMTFKDLGMDDL 1205
             D+    S+    +          S   V   D+ R   L V     ++   F  L   + 
Sbjct: 23345 DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNE 23404

Query: 1206  GIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQ 1265
              ++    T+  GI  SYL  E     ++      + P  P   ++  ++   G    W  
Sbjct: 23405 YVFRVAATNRFGI-GSYLQSE-----VIECRSSIRIPGPPETLQI-FDVSRDGMTLTWYP 23457

Query: 1266  AEKLSGNAKVNYIFNEKEI 1284
              E   G+    YI   KE+
Sbjct: 23458 PEDDGGSQVTGYIVERKEV 23476



 Score =  131 bits (329), Expect = 6e-30
 Identities = 97/326 (29%), Positives = 140/326 (42%), Gaps = 46/326 (14%)

Query: 418  EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDE 477
            EGE +S+       P      P + W+++G  +  S  +        A L      + D 
Sbjct: 7903 EGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 7957

Query: 478  GLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAV 535
            G+YTI +  ++G               + ++ G P    D+K  +  K    ++W+ P  
Sbjct: 7958 GIYTITLENKLGSA---------TASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 8008

Query: 536  DGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFP 595
            DGG+PIL Y +++ E G  ++        K + + V  LI    Y FRV+AVNK+G G  
Sbjct: 8009 DGGTPILHYVLERREAGRRTYIPVMSGENKLS-WTVKDLIPNGEYFFRVKAVNKVGGGEY 8067

Query: 596  SRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVV 655
              +  PV A DP +                            P PP D+ V   T   + 
Sbjct: 8068 IELKNPVIAQDPKQP---------------------------PDPPVDVEVHNPTAEAMT 8100

Query: 656  LSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRC 714
            ++WKPP   G   IM Y +EK   G E W+R N  L V    +    L EGK Y FRVR 
Sbjct: 8101 ITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRA 8159

Query: 715  SNSAGVGEPSEATEVTVVGDKLDIPK 740
             N+AG+ EPS AT  T   D +D PK
Sbjct: 8160 ENAAGISEPSRATPPTKAVDPIDAPK 8185



 Score =  129 bits (323), Expect = 3e-29
 Identities = 129/471 (27%), Positives = 187/471 (39%), Gaps = 95/471 (20%)

Query: 288   VWEKENVKLHCSIAGWPEPRVTWYK-------NQVPINVHANPGKYIIESRYGMHTLEIN 340
             V E  NV +   I G P P +TW+K       N+ P+    +  K +++      TL I 
Sbjct: 9631  VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTC---TLVIP 9687

Query: 341   GCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYA 400
                  DT  Y  +A+N  G  S               E R +      P      P G  
Sbjct: 9688  QSRRSDTGLYTITAVNNLGTAS--------------KEMRLNVLGRPGP------PVG-P 9726

Query: 401   SRFEIHFDDKFDVS-FGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTL 459
              +FE    D+  +S F  + +  S     VI                    +   WV   
Sbjct: 9727  IKFESVSADQMTLSWFPPKDDGGSKITNYVIEKR---------------EANRKTWVHVS 9771

Query: 460   WSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGA------PAAP 513
                +  T T   L +  E ++ I  +        + Y      D+E E A      P AP
Sbjct: 9772  SEPKECTYTIPKLLEGHEYVFRIMAQ--------NKYGIGEPLDSEPETARNLFSVPGAP 9823

Query: 514   LDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKF----ARF 569
                      ++ + ++W++P  DGGSP+ GY+++  +  +  W + N  P+K       +
Sbjct: 9824  DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSY 9883

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGLIEG  Y FRV A+N  G+G  S  S+P  A DP           AP         
Sbjct: 9884  KVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPI----------AP--------- 9924

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT 688
                     PGPP    VT+ T+S   L W PP + G   +  Y VE  E G E W++   
Sbjct: 9925  --------PGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEK-GK 9974

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 739
             +  V+  +  +  L EG  Y FRVR  N AG+GEP E T+V  + D+L  P
Sbjct: 9975  DKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP 10025



 Score =  125 bits (313), Expect = 5e-28
 Identities = 183/774 (23%), Positives = 298/774 (38%), Gaps = 129/774 (16%)

Query: 274   LHAPEFIIKP---RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIES 330
             L APE  I     ++H V    +++L  +  G P P   W K    +++ A+     I +
Sbjct: 21855 LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD-----IHT 21909

Query: 331   RYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
                  TL +  C+  D  +Y  +  N  G  S   +V V    G              P+
Sbjct: 21910 TDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-----------PGPI 21958

Query: 391   SFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPL 450
             +F     G A+                +   +  G R      I H+  E +        
Sbjct: 21959 TFKDVTRGSATLMW-------------DAPLLDGGAR------IHHYVVEKR------EA 21993

Query: 451   SPSKWVQTLWSGERATLTFSHLNKEDEGL-YTIRVRMGEYYEQYSAYVFVRDADAEIEGA 509
             S   W Q +   E+ T     +N   EG+ Y  RV     Y     Y       A  + A
Sbjct: 21994 SRRSW-QVI--SEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPA 22050

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P   LDV  ++ +K   +++W +P  DGGS I GY ++  + G+D W +   T  K   F
Sbjct: 22051 PPRRLDV--VDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT--KQLTF 22106

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTG---QII 626
              V  L+E   Y FRV+A N  G   P      V   +P      +  P+A  TG   Q+I
Sbjct: 22107 TVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEP------QIEPTADLTGITNQLI 22160

Query: 627   VTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRV 686
               +         G P  + V  + R    ++WK    R        +++ +  +    + 
Sbjct: 22161 TCK--------AGSPFTIDVPISGRPAPKVTWKLEEMR--------LKETDRVSITTTKD 22204

Query: 687   NTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKII 746
              T L VK       D   G S  + +   N+AGV   + +  V V+G    +    G I 
Sbjct: 22205 RTTLTVK-------DSMRGDSGRYFLTLENTAGV--KTFSVTVVVIGRPGPV---TGPIE 22252

Query: 747   PSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTG 804
              S  +  S V+SW E KD    E+  Y +E   +G+  W+  N++ VK ++     L   
Sbjct: 22253 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLTKY 22311

Query: 805   QSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV--- 861
               Y FRV + N  G+S+  + +  I           P V P+    P     S   +   
Sbjct: 22312 MEYSFRVSSENRFGVSKPLESAPII--------AEHPFVPPSAPTRPEVYHVSANAMSIR 22363

Query: 862   -----HEASPPTF-------QKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTP 909
                  H+             +++ +L  K NK  +P    N    +V+ + E ++ +   
Sbjct: 22364 WEEPYHDGGSKIIGYWVEKKERNTILWVKENK--VPCLECNY---KVTGLVEGLEYQFRT 22418

Query: 910   PPQKAAPQGKSK--SDPLKKKTDRAPPSPP--CDITCLESFRDSMVLGWKQPDKIGGAEI 965
                 AA   K+   S P+  +     P  P   D+T     R ++ L W  P   GG+++
Sbjct: 22419 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVT-----RSTVSLIWSAPAYDGGSKV 22473

Query: 966   TGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 1019
              GY +  + V +   G+W + N   VS+  + ++ L E   Y+F+V A N AG+
Sbjct: 22474 VGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGV 22527



 Score =  122 bits (307), Expect = 2e-27
 Identities = 234/997 (23%), Positives = 368/997 (36%), Gaps = 139/997 (13%)

Query: 508  GAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFA 567
            G P +P  +   E  K  I + WK+P  +GGSPI GY I+K       + + N       
Sbjct: 8796 GPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTT 8855

Query: 568  RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALD---PAEKARLKSRPSAPWTGQ 624
             F V  L E + Y FRV+AVN++G   PS     V   D   P  K RL  R        
Sbjct: 8856 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDT----- 8910

Query: 625  IIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQ 684
            I V   EP    +P   T L + +       + W     +    I    +  +   E   
Sbjct: 8911 IKVKAGEPVH--IPADVTGLPMPK-------IEWS----KNETVIEKPTDALQITKEEVS 8957

Query: 685  RVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGK 744
            R   +  +  P+    D        + V  SN  G    +   EV       D P  P  
Sbjct: 8958 RSEAKTELSIPKAVREDKGT-----YTVTASNRLGSVFRNVHVEV------YDRPSPPRN 9006

Query: 745  IIPSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGSGK--WEPCNNNPVKGSRFTCHG 800
            +  +     S  ++W+   D    E+  Y I+   A   K  WE   N  V+  R+    
Sbjct: 9007 LAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVE-KRYGIWK 9065

Query: 801  LVTGQSYIFRVRAVNAAGLSEYSQDSEAI--------------EVKAAIGGGVSPDVCPA 846
            L+    Y FRVRAVN  G+S+  +  + +              +V A   G +     P 
Sbjct: 9066 LIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPP 9125

Query: 847  LSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEE 906
            L +    +T       E   P +       S+ ++  +        +  V ++ E V+ +
Sbjct: 9126 LDNGGSPITGYWLEKREEGSPYW-------SRVSRAPITKVGLKGVEFNVPRLLEGVKYQ 9178

Query: 907  LTPPPQKAAPQG--KSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 964
                   AA  G     SDP        PP PP      +  + S+ LGWK P K GG+ 
Sbjct: 9179 FRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSP 9238

Query: 965  ITGYYVNYREVIDGVPGKWREANV--KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
            I GY V  +E  +G    W+  N   K ++     + NLKE   Y+F+V A+N AG   P
Sbjct: 9239 IKGYIVEMQE--EGTTD-WKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEP 9295

Query: 1023 SAVSECFKC----EEWTIAVP-GPPHSLKCSEVRKDSLVLQWKPPVHSGR-TPVTGYFVD 1076
            S  +         EE  + +  G    L C    +  +     P V  GR TP + +  D
Sbjct: 9296 SDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRI-----PAVIKGRPTPKSSWEFD 9350

Query: 1077 LKEAKAKEDQWRGLNE-----AAIKNVYLKVRGLKEGVSYVFRVRAINQAGVG------K 1125
             K  KA +D    + E      A  +  + +   K   +  + + A N+AG        K
Sbjct: 9351 GKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVK 9410

Query: 1126 PSDLAGP-----VVAETRPGTKEVVVNVDDDGVISLN-FECDKMTPKSEFSWSKDYVSTE 1179
              D+ GP     V   TR   +      DDDG   +  +  +K T   + +W+K      
Sbjct: 9411 VMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGK-AWTK------ 9463

Query: 1180 DSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEH 1239
                  V      T     DL  +    +     +  GI        E ++R  A    +
Sbjct: 9464 ------VNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPV----ETIQRTTARDPIY 9513

Query: 1240 KFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFE--GPKYKMHIDRN 1297
              P  P+K  L + ++ K  V    +  K  G + V +   E   ++  G K +     N
Sbjct: 9514 P-PDPPIK--LKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN 9570

Query: 1298 TGIIEMFMEKLQDEDEG-TYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQ 1356
               +E     ++D  EG  Y F++   KA N + V          +  A     +  R  
Sbjct: 9571 KRDVEELQFTVEDLVEGGEYEFRV---KAVNAAGVS---------KPSATVGPCDCQRPD 9618

Query: 1357 GPHFVEYLSW-EVTGECNVLLKCKVANIKKETHIVWYK------DEREISVDEKHDFK-- 1407
             P  ++   + EV    NV +  K+  +   T + W+K      D +E  + + H  K  
Sbjct: 9619 MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPT-LTWFKAPPKKPDNKEPVLYDTHVNKLV 9677

Query: 1408 -DGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
             D  CTL+I +  + D G+Y +   ++ G     ++L
Sbjct: 9678 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9714



 Score =  121 bits (304), Expect = 5e-27
 Identities = 115/467 (24%), Positives = 177/467 (37%), Gaps = 86/467 (18%)

Query: 287   TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
             TV   + ++L   + G P P V W K++   ++  +P +  I++R       +      D
Sbjct: 11715 TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSD 11773

Query: 347   TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
               +Y  +A N  G   AYA+V V    G     +                          
Sbjct: 11774 GGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKI------------------------- 11808

Query: 407   FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                  DVS  R        C V   P       EIQ Y     L   +  + +WS   AT
Sbjct: 11809 ----VDVSSDR--------CTVCWDPPEDDGGCEIQNY----ILEKCETKRMVWSTYSAT 11852

Query: 467   L-----TFSHLNKEDEGLYTIRV--RMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCL 519
             +     T + L + +E ++ +R   ++G      S  V  +         P  P   +  
Sbjct: 11853 VLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTK----YDKPGRPDPPEVT 11908

Query: 520   EANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRS 579
             + +K+ + + W  P  DGG  I GYF++K E  +  W   N + +   R  V  L+    
Sbjct: 11909 KVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHE 11968

Query: 580   YIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPG 639
             Y FRV+A N++GIG PS  S PV A DP E                            PG
Sbjct: 11969 YQFRVKAENEIGIGEPSLPSRPVVAKDPIEP---------------------------PG 12001

Query: 640   PPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCE------AGTENWQRVNTELPVK 693
             PPT+  V + T+  + L W  P   G   I+ +V +        +  E W+R N    + 
Sbjct: 12002 PPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLV 12061

Query: 694   SPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
                F +  L E + Y FRV   N  G+G P+E  E     + L+ P+
Sbjct: 12062 RKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPE 12108



 Score =  120 bits (300), Expect = 1e-26
 Identities = 118/471 (25%), Positives = 184/471 (39%), Gaps = 81/471 (17%)

Query: 277   PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
             P   +   ++++   E++K+   + G P P ++W K+  P+       +  +E       
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLK---QTTRVNVEETATSTV 17871

Query: 337   LEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTP 396
             L I   + +D  +Y  +A N  G  +   SV+V    G                     P
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--------------------PP 17911

Query: 397   YGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWV 456
              G     E+  D    V    E    + GC++      K       W+     ++     
Sbjct: 17912 VGPVRFDEVSAD---FVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVA----- 17963

Query: 457   QTLWSGERATLTFSHLNKEDEGLYTIRV----RMGEYYEQYSAYVFVRDADAEIEGAPAA 512
                    R T+  + L    E  Y  R+    R G+     S  V V+    E  G P  
Sbjct: 17964 -------RTTIKITKLKTGTE--YQFRIFAENRYGKSAPLDSKAVIVQYPFKE-PGPPGT 18013

Query: 513   PLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVT 572
             P        +KD +++ W +P  DGG+ I+GY +++ E  +  W + N TP++  +F  T
Sbjct: 18014 PF---VTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTT 18070

Query: 573   GLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEP 632
             GL EG  Y F+V A N +GIG PS+VSE   A DP +                       
Sbjct: 18071 GLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDP---------------------- 18108

Query: 633   SEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELP 691
                  PG P  + +   TR+ V L WK P   G   I  Y VEK +     W + +    
Sbjct: 18109 -----PGRPEAIVI---TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASF-TN 18159

Query: 692   VKSPRFALFDLAEGKSYCFRVRCSNSAG-VGEPSEATEVTVVGDKLDIPKA 741
             V    F +  L E + Y FRV   N+AG   EPS+++      D++D P A
Sbjct: 18160 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNA 18210



 Score =  117 bits (293), Expect = 9e-26
 Identities = 95/316 (30%), Positives = 144/316 (45%), Gaps = 39/316 (12%)

Query: 510  PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
            P+ PLD+   +A + +I I+WK P  +GGSPI+GY ++ C VGT+ W + N  P+K  +F
Sbjct: 7788 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 7847

Query: 570  PV-TGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVT 628
             V  G++  + Y+ RVRAVN +G+  PS +SE V A DP  K  +        T  IIV 
Sbjct: 7848 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLE-----THDIIVI 7902

Query: 629  EEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNT 688
            E E     +P P   + V         +SW   G+         V+  +  T     ++ 
Sbjct: 7903 EGEKLS--IPVPFRAVPVP-------TVSWHKDGKE--------VKASDRLTMKNDHISA 7945

Query: 689  ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPS 748
             L V  P+    D        + +   N   +G  + +  V V+G    +P     I  S
Sbjct: 7946 HLEV--PKSVRADAG-----IYTITLENK--LGSATASINVKVIG----LPGPCKDIKAS 7992

Query: 749  RNTDTSVVVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQS 806
              T +S  ++WE  E      ++ Y +E   AG   + P  +   K S +T   L+    
Sbjct: 7993 DITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLS-WTVKDLIPNGE 8051

Query: 807  YIFRVRAVNAAGLSEY 822
            Y FRV+AVN  G  EY
Sbjct: 8052 YFFRVKAVNKVGGGEY 8067



 Score =  117 bits (292), Expect = 1e-25
 Identities = 89/308 (28%), Positives = 141/308 (45%), Gaps = 18/308 (5%)

Query: 922   SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPG 981
             SDP+  +     P  P          +S+ L W +P+  GG+EI  Y +  RE       
Sbjct: 21643 SDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKST--- 21699

Query: 982   KW-REANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
             +W +  + + +SE  +K++ L E   Y+F V A N AG+G  S +S   KC E  +  PG
Sbjct: 21700 RWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCRE-PVNPPG 21758

Query: 1041  PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLN-EAAIKNVY 1099
             PP  +K ++  K ++ L+W  PV  G   + GY +++   KA    W  +N EA +K  Y
Sbjct: 21759 PPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEM--CKADLGDWHKVNAEACVKTRY 21816

Query: 1100  LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVV-------NVDDDG 1152
               V  L+ G  Y FRV AIN AG G   ++ G + A  R    E+ +       +V   G
Sbjct: 21817 -TVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAG 21875

Query: 1153  VISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDV 1212
                  F   +  P     WSK    +  S R ++ +  + + +T ++   +D G Y+  V
Sbjct: 21876 ASIRLFIAYQGRPTPTAVWSKP--DSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTV 21933

Query: 1213  TDTDGIAS 1220
              +  G  S
Sbjct: 21934 ENNSGSKS 21941



 Score =  116 bits (290), Expect = 2e-25
 Identities = 133/548 (24%), Positives = 220/548 (40%), Gaps = 61/548 (11%)

Query: 638   PGPPTD-LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             PGPP   +   E +  +VV+SW+PP   G   I  Y VEK +  T  W  V+    V   
Sbjct: 17908 PGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSAT--VART 17965

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
                +  L  G  Y FR+   N  G   P ++  V +V      P  PG    +  +   +
Sbjct: 17966 TIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAV-IVQYPFKEPGPPGTPFVTSISKDQM 18024

Query: 756   VVSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRA 813
             +V W E  +    +++GY++E     S  W   N  P++ ++F   GL  G  Y F+V A
Sbjct: 18025 LVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA 18084

Query: 814   VNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG-----LTASRGRVHEASPPT 868
              N  G+ + S+ SE           V+ D C    D PG      +T +   +    P  
Sbjct: 18085 ENIVGIGKPSKVSECF---------VARDPC----DPPGRPEAIVITRNNVTLKWKKPAY 18131

Query: 869   FQKDALLGSKPNKPSLP------SSSQNLGQTE--VSKVSETVQEELTPPPQKAAPQGKS 920
                  + G    K  LP      +S  N+ +TE  VS + E  + E     + AA     
Sbjct: 18132 DGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSE 18191

Query: 921   KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
              SD     T R     P + +    ++D +V+        G   +    +  + + D V 
Sbjct: 18192 PSDSSGAITARDEIDAP-NASLDPKYKDVIVV------HAGETFVLEADIRGKPIPDVVW 18244

Query: 981   GKWREANVKAVSEEAYKISNLKENMVYQFQVAA------MNMAGLGAPSAVSECFKCEEW 1034
              K  +   +  +    K +  K  +V +  +        + ++ +G   ++    K    
Sbjct: 18245 SKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVK---- 18300

Query: 1035  TIAVPGPPHS-LKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
              +  PGPP   LK + V  +   L W PP+  G   ++ Y ++ +E       W  ++  
Sbjct: 18301 VLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS--WTQVS-T 18357

Query: 1094  AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA------ETRPGTKEVVVN 1147
              ++ +  KV  L  G  Y+FRV A+N+ G+G+P + +GPV A         P T EV   
Sbjct: 18358 EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLE-SGPVTACNPYKPPGPPSTPEVSAI 18416

Query: 1148  VDDDGVIS 1155
               D  V++
Sbjct: 18417 TKDSMVVT 18424



 Score =  115 bits (289), Expect = 3e-25
 Identities = 166/757 (21%), Positives = 275/757 (36%), Gaps = 129/757 (17%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             E +K++  IAG P P ++W K+ + I   A   +  I S      L +  C   DT QY 
Sbjct: 19308 EVLKINADIAGRPLPVISWAKDGIEIEERA---RTEIISTDNHTLLTVKDCIRRDTGQYV 19364

Query: 352   ASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF-GVTPYGYASRFEIHFDDK 410
              +  NV G  S   +  V       D+    AG    PL   G+T             +K
Sbjct: 19365 LTLKNVAGTRSVAVNCKV------LDKPGPPAG----PLEINGLTA------------EK 19402

Query: 411   FDVSFGREGET--MSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGE--RAT 466
               +S+GR  E     +   +V   E  H    + W              T+  GE    +
Sbjct: 19403 CSLSWGRPQEDGGADIDYYIVEKRETSH----LAW--------------TICEGELQMTS 19444

Query: 467   LTFSHLNKEDEGLYTI----RVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEAN 522
                + L K +E ++ +    +  +GE  E     V ++  D      P+ P  ++     
Sbjct: 19445 CKVTKLLKGNEYIFRVTGVNKYGVGEPLES----VAIKALDPFT--VPSPPTSLEITSVT 19498

Query: 523   KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIF 582
             K+ + + W +P  DGGS I GY I++ E  +  W + N  PV   R   TGL EG  Y +
Sbjct: 19499 KESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEY 19558

Query: 583   RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
             RV A N  G+  PS  S  + A DP                             +P PP+
Sbjct: 19559 RVYAENAAGLSLPSETSPLIRAEDPV---------------------------FLPSPPS 19591

Query: 643   DLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFD 701
                + ++ ++ + ++W KP    G     Y VE  ++   +W+     L  +   + +  
Sbjct: 19592 KPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL--RGTEYTISG 19649

Query: 702   LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK-------LDIPKAPGKIIPSRNTDTS 754
             L  G  Y FRV+  N  G  +PS++++  +  ++       +D       I+ +  + T 
Sbjct: 19650 LTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTM 19709

Query: 755   VV---------VSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQ 805
              V         V W +         Y        S   E  N N       T   +++  
Sbjct: 19710 TVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA 19769

Query: 806   SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEAS 865
             S    V+ ++  G        +  +  A +   V         +  GG       + +  
Sbjct: 19770 SLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV--------PENDGGAPVKNYHIEKRE 19821

Query: 866   PPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPL 925
                  K A +    N   L     NL +  +     + + E          +G       
Sbjct: 19822 A---SKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEG------- 19871

Query: 926   KKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWRE 985
              K T++  P     +T +   +DS+ L W +P+  GG+ I  Y V   E ++     W +
Sbjct: 19872 VKITEKPSPPEKLGVTSIS--KDSVSLTWLKPEHDGGSRIVHYVV---EALEKGQKNWVK 19926

Query: 986   ANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
               V       + +S L+EN  Y F+V A N AGL  P
Sbjct: 19927 CAV--AKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 19961



 Score =  113 bits (282), Expect = 2e-24
 Identities = 82/300 (27%), Positives = 136/300 (45%), Gaps = 26/300 (8%)

Query: 934   PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
             P PP          D M L W  P   GG+E+TG++V  +E    +   W++ N   +S 
Sbjct: 21260 PGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSIL---WQKVNTSPISG 21316

Query: 994   EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVP--GPPHSLKCSEVR 1051
               Y+ + L E + YQF+V A N AGL +PS  S+      +T+AV    PP +    +V 
Sbjct: 21317 REYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK------FTLAVSPVDPPGTPDYIDVT 21370

Query: 1052  KDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSY 1111
             ++++ L+W PP+  G + + GY ++ ++     ++W   N   +      V GL  G  Y
Sbjct: 21371 RETITLKWNPPLRDGGSKIVGYSIEKRQGN---ERWVRCNFTDVSECQYTVTGLSPGDRY 21427

Query: 1112  VFRVRAINQAG-VGKPSDLAGPVVAETRPGTKEVVVNVDD---DGVISLNFECDKMT--- 1164
              FR+ A N  G +  PS  +G ++  TR      +V       DG+I  + E  ++    
Sbjct: 21428 EFRIIARNAVGTISPPSQSSGIIM--TRDENVPPIVEFGPEYFDGLIIKSGESLRIKALV 21485

Query: 1165  ---PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS 1221
                P    +W KD V  E    +E+      T +  +D   D  G+Y+ +  +  G A +
Sbjct: 21486 QGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKA 21545



 Score =  112 bits (279), Expect = 4e-24
 Identities = 71/232 (30%), Positives = 103/232 (44%), Gaps = 28/232 (12%)

Query: 510   PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
             P  P   +     KD ++++W +P  DGG+ I GY ++K +     W++CN   +   R 
Sbjct: 18405 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRL 18464

Query: 570   PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
              VTGL EG SY FRV A N  G+G PS  S    A D                       
Sbjct: 18465 RVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDAL--------------------- 18503

Query: 630   EEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNT 688
                     PGPP++  VT+ +RS V L+W  P   G   +  Y VE  EA  + W     
Sbjct: 18504 ------YPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTP 18557

Query: 689   ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
                ++  +F +  L E   Y FR+   NS GVGEP+      V  ++++ P+
Sbjct: 18558 PTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18609



 Score =  108 bits (269), Expect = 6e-23
 Identities = 127/511 (24%), Positives = 214/511 (41%), Gaps = 52/511 (10%)

Query: 638   PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
             PGPP  + + E +   + +SW PP   G   I  Y VEK E  +  W  V+  +   S +
Sbjct: 18991 PGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIK 19050

Query: 697   FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 756
               +  L  G  Y FRV   N  G    SE++ V V       P  PG       T ++++
Sbjct: 19051 --IVRLTTGSEYQFRVCAENRYGKSSYSESSAV-VAEYPFSPPGPPGTPKVVHATKSTML 19107

Query: 757   VSWEE--SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAV 814
             V+W+   +     ++GY++E     S  W   N   +  ++    GL  G  Y +RV A 
Sbjct: 19108 VTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAE 19167

Query: 815   NAAGLSEYSQDSEAIEVKAAIGGGVSPDVC-PALSDEPGGLTASRGRVHEASPPTFQKDA 873
             N AG+ + S+  E +  +         D C P    E   +T     +  + P       
Sbjct: 19168 NIAGIGKCSKSCEPVPAR---------DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAK 19218

Query: 874   LLGSKPNKPSLPS------SSQNLGQT--EVSKVSETVQEELTPPPQKAAPQGKSKSD-- 923
             + G    +  LP       +  N+ +T  EV++++E  + E     + AA      S+  
Sbjct: 19219 ITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSEST 19278

Query: 924   -PLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGY---YVNYREVIDGV 979
              P+  K D  PP    D+     FRD +V+   +  KI  A+I G     +++ +  DG+
Sbjct: 19279 GPIIVKDDVEPPRVMMDV----KFRDVIVVKAGEVLKI-NADIAGRPLPVISWAK--DGI 19331

Query: 980   PGKWREANVKAVSEEAYKISNLKENM---VYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
               + R A  + +S + + +  +K+ +     Q+ +   N+AG       S    C+   +
Sbjct: 19332 EIEER-ARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG-----TRSVAVNCK--VL 19383

Query: 1037  AVPGPPHS-LKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 1095
               PGPP   L+ + +  +   L W  P   G   +  Y V+ +E       W  + E  +
Sbjct: 19384 DKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE--TSHLAWT-ICEGEL 19440

Query: 1096  KNVYLKVRGLKEGVSYVFRVRAINQAGVGKP 1126
             +    KV  L +G  Y+FRV  +N+ GVG+P
Sbjct: 19441 QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 19471



 Score =  107 bits (267), Expect = 1e-22
 Identities = 81/279 (29%), Positives = 125/279 (44%), Gaps = 45/279 (16%)

Query: 462  GERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEA 521
            G ++ L      ++D G Y I         +++A      A  E+   P   LD+K +  
Sbjct: 8659 GTKSELIIKDALRKDHGRYVITAT-NSCGSKFAA------ARVEVFDVPGPVLDLKPVVT 8711

Query: 522  NKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYI 581
            N+   +++W  P  DGGS I G+ I++ +    +W Q  +T  + ++  +TGL+EG+ Y 
Sbjct: 8712 NRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIET--ERSKCDITGLLEGQEYK 8769

Query: 582  FRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPP 641
            FRV A NK G G P  +  P+ A+DP                               GPP
Sbjct: 8770 FRVIAKNKFGCGPPVEIG-PILAVDPL------------------------------GPP 8798

Query: 642  TD---LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRF 697
            T    L+ TE T+S + L WK P   G   I  Y +EK      +++RVN  L   +  F
Sbjct: 8799 TSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSF 8857

Query: 698  ALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
             + +L E + Y FRV+  N  G  EPS    V +  D++
Sbjct: 8858 LVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEV 8896



 Score =  103 bits (256), Expect = 2e-21
 Identities = 71/193 (36%), Positives = 91/193 (47%), Gaps = 7/193 (3%)

Query: 638   PGPPTD-LSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             PGPP   L VT  T     L+W PP Q G   I  Y +EK E    +W +V+TE  V++ 
Sbjct: 18305 PGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTE--VQAL 18362

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
              + +  L  G  Y FRV   N  G+GEP E+  VT   +    P  P     S  T  S+
Sbjct: 18363 NYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTAC-NPYKPPGPPSTPEVSAITKDSM 18421

Query: 756   VVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRA 813
             VV+W    D    E+ GY +E       +W  CN   +   R    GL  G SY FRV A
Sbjct: 18422 VVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAA 18481

Query: 814   VNAAGLSEYSQDS 826
              NAAG+ E S+ S
Sbjct: 18482 ENAAGVGEPSEPS 18494



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 161/728 (22%), Positives = 271/728 (37%), Gaps = 135/728 (18%)

Query: 497   VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
             VF R  DA     P  P + K  + ++  + ++W +P  DGG+P+ GY ++  E   D W
Sbjct: 18495 VFYRACDALYP--PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW 18552

Query: 557   SQCND-TPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKS 615
             + C   T ++  +F VT L E   Y FR+ A+N  G+G P+ +   V A +  E   ++ 
Sbjct: 18553 TTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIEL 18612

Query: 616   RPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQ---RGHEGIMYF 672
                     +++V                L  +   R +V +  +P  +      EGI+  
Sbjct: 18613 DAD---LRKVVV----------------LRASATLRLFVTIKGRPEPEVKWEKAEGIL-- 18651

Query: 673   VEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV 732
                         R   E+        + ++    S  + +   N++G    S+   V V 
Sbjct: 18652 ----------TDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSG----SKTAFVNV- 18696

Query: 733   GDKLDIPKAPGKIIPSRNTDTSVVVSWEES--KDAKELVGYYIEASVAGSGKWEPCNNNP 790
                LD P AP  +        SV +SWE        ++  Y +E        +    NN 
Sbjct: 18697 -RVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNC 18755

Query: 791   VKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDE 850
              K + F    L  G SY FRV A N  G+   ++ +E ++V             P L   
Sbjct: 18756 TK-TTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSE-----------PPL--P 18801

Query: 851   PGGLTASRGRVHEASPPTFQKDALLGSKPN----KPSLPSSSQNLGQTEVSKVSETVQEE 906
             PG +T      + A+    + ++  GSK      +     S +    T+V  +  T+   
Sbjct: 18802 PGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATI-SG 18860

Query: 907   LTPPPQ----KAAPQGKSKSDP-----------LKKKTDRAPPSPPCDITCLESF----- 946
             LT   +     AA   K +SDP           ++ K     P    ++   E       
Sbjct: 18861 LTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVP 18920

Query: 947   ---RDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKE 1003
                R    + W++ D     E T   V+  + +  +  K  EA+ + V      +SN   
Sbjct: 18921 FKGRPQATVNWRK-DGQTLKETTRVNVSSSKTVTSLSIK--EASKEDVGTYELCVSNSAG 18977

Query: 1004  NMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPV 1063
             ++     +  ++  G   P  + E   C+  TI+                     W PP 
Sbjct: 18978 SITVPITIIVLDRPGPPGPIRIDE-VSCDSITIS---------------------WNPPE 19015

Query: 1064  HSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGV 1123
             + G   ++ Y V+ KE  +    W  +++ A+    +K+  L  G  Y FRV A N+ G 
Sbjct: 19016 YDGGCQISNYIVEKKETTS--TTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGK 19072

Query: 1124  GKPSDLAGPVVAE------TRPGTKEVV------------VNVDDDGVISLNFECDKMTP 1165
                S+ +  VVAE        PGT +VV            V V+D G   + +  +    
Sbjct: 19073 SSYSE-SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLE-YKE 19130

Query: 1166  KSEFSWSK 1173
             +S   WSK
Sbjct: 19131 RSSILWSK 19138



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 84/340 (24%), Positives = 135/340 (39%), Gaps = 45/340 (13%)

Query: 274   LHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYII-ESRY 332
             + AP F  + R+  V  + N  L C + G P+P V WY+    I   A+  KY I E + 
Sbjct: 24428 IQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEII--ADGLKYRIQEFKG 24485

Query: 333   GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF 392
             G H L I     +D   Y+  A N  G +S  AS+ V+         + H   +   +  
Sbjct: 24486 GYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEV------PAKIHLPKTLEGMGA 24539

Query: 393   GVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSP 452
                  G     +I F  K D                          P I W +    +  
Sbjct: 24540 VHALRGEVVSIKIPFSGKPD--------------------------PVITWQKGQDLIDN 24573

Query: 453   SKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPA 511
             +   Q + +    +L F + + ++D G Y +  +     +Q       +  + ++   P 
Sbjct: 24574 NGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQ-------KTVELDVADVPD 24626

Query: 512   APLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPV 571
              P  VK  + ++D + ++W +PA DGGS I  Y ++KC    + W +      +  R+ V
Sbjct: 24627 PPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ--ARETRYTV 24684

Query: 572   TGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKA 611
               L    SY FRV A NK G+  PS  SEP    +   +A
Sbjct: 24685 INLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRA 24724



 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 58/224 (25%), Positives = 109/224 (48%), Gaps = 17/224 (7%)

Query: 157   ERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTA 216
             E +K++AA   +++++  E  IT + Q++   +T A  ++ +++ S    Q    + + A
Sbjct: 26509 EEVKKSAATSLEKSIVHEE--ITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIA 26566

Query: 217   SRQSVV----SKQATSALQQEETSEKKSRKVVIREKAER-----LSLRKTLEETET--YH 265
                 V       + T++ +         + + I++ + R       + KT E      Y 
Sbjct: 26567 GATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYD 26626

Query: 266   AKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGK 325
               L+++ L  AP FI +PRS  + E +NV   C I+G P P + W+KN +PI++ +N   
Sbjct: 26627 LTLSKE-LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVS- 26684

Query: 326   YIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
               I     +++LEI      D+ +Y   A N +G+ SA AS++V
Sbjct: 26685 --ISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 104/533 (19%), Positives = 203/533 (38%), Gaps = 97/533 (18%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            F C+  T  ++  W ++  +  DS +  +  K     +  +D  +DD   Y+  +T+  G
Sbjct: 6162 FNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 6221

Query: 1218 ----IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
                 A++ +++EE+L+ +            P+K    +E +EK  V FW +  +L  N 
Sbjct: 6222 ENVKSAANLIVEEEDLRIV-----------EPLKD---IETMEKKSVTFWCKVNRL--NV 6265

Query: 1274 KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1333
             + +  N +E+    +    +D+   ++ +  +     DEG Y       K+     ++ 
Sbjct: 6266 TLKWTKNGEEVPFDNRVSYRVDKYKHMLTI--KDCGFPDEGEYIVTAGQDKSVAELLII- 6322

Query: 1334 VGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECN-VLLKCKVANIKKETHIVWY 1392
                                 +    FVE+L  +   E +  +  C+++  +++ ++ WY
Sbjct: 6323 ---------------------EAPTEFVEHLEDQTVTEFDDAVFSCQLS--REKANVKWY 6359

Query: 1393 KDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKE-- 1450
            ++ REI   +K+ F+             KD  I+ +I+KD R  D+       E  K   
Sbjct: 6360 RNGREIKEGKKYKFE-------------KDGSIHRLIIKDCRLDDECEYACGVEDRKSRA 6406

Query: 1451 --LMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTG 1508
               + E+  +I     D+     A G  +        + ++V W  N   +   D+ +  
Sbjct: 6407 RLFVEEIPVEIIRPPQDIL---EAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMM 6463

Query: 1509 VTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAE 1568
              G+   LQI +  P D+G+Y     D                 EA A+ +      I  
Sbjct: 6464 SEGKIHRLQICDIKPRDQGEYRFIAKD----------------KEARAKLELAAAPKIKT 6507

Query: 1569 KNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRT 1628
             ++  V         +  GK L +       P  E  W K  + L++     +   A +T
Sbjct: 6508 ADQDLV---------VDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK---TIDTTAEQT 6555

Query: 1629 AYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVF-IPEEEARMAALESLKG 1680
            + F I      D G+Y +V++NK+G       + V  +P     +   E+  G
Sbjct: 6556 S-FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6607



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 67/296 (22%), Positives = 117/296 (39%), Gaps = 27/296 (9%)

Query: 1378  CKVANIKKETHIVWYKDEREISVDEKHD--FKDGICTLLITEFSKKDAGIYEVILKDDRG 1435
             CK+ N  + T + WY   R++   EK++  ++DG+  L + + +K D G Y   + +D G
Sbjct: 25092 CKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYG 25151

Query: 1436  KDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHN 1495
             +D S  +L  +  +E+    C++     T  KI+   + ++L      +   L    ++ 
Sbjct: 25152 EDSSYAELFVKGVREVYDYYCRR-----TMKKIKRRTDTMRLLERPPEFTLPLYNKTAYV 25206

Query: 1496  GSAIRYSDRVKTGVTGEQIWLQINE---PTPNDKGKYVMELFDGKTGHQKTVDLSGQAYD 1552
             G  +R+   +         W +  +   P  NDK KY  E    K  +Q T++      D
Sbjct: 25207 GENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDK-KYTFE--SDKGLYQLTINSVTTDDD 25263

Query: 1553  EAYAEFQRLKQAAIAEKNRARVLGGLPDV--------------VTIQEGKALNLTCNVWG 1598
               Y    R K    + K +  V    P                   QEG+++     V G
Sbjct: 25264 AEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 25323

Query: 1599  DPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGS 1654
              PPP + W K+ + L+   +  +  E        I      D+G Y +   N  GS
Sbjct: 25324 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGS 25379



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 102/489 (20%), Positives = 180/489 (36%), Gaps = 79/489 (16%)

Query: 1165 PKSEFSWSKDYVSTEDSPRLE-VESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            P  E  W K+ V  E S R+     + N  ++  +D+  +D         +  G  SS+ 
Sbjct: 2059 PDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHA 2118

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
                + K+L+  + E +      K  +A             + E      KV +  +  E
Sbjct: 2119 FLLVQAKQLITFTQELQDVVAKEKDTMAT-----------FECETSEPFVKVKWYKDGME 2167

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQK 1343
            + EG KY+MH DR    + +      D ++ +    ++D      + +++ G V + +++
Sbjct: 2168 VHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVL-VEDENVKTTAKLIVEGAVVEFVKE 2226

Query: 1344 EAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVA--NIKKETHIVWYKDEREISVD 1401
              + +  E                 +GE    L+C V+  NI+ +    WY ++ E+  +
Sbjct: 2227 LQDIEVPE---------------SYSGE----LECIVSPENIEGK----WYHNDVELKSN 2263

Query: 1402 EKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKI 1459
             K+    + G   L + + +K+D G Y  ++  D  K   +LK+       L        
Sbjct: 2264 GKYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKTTCKLKMKPRPIAILQ------- 2314

Query: 1460 ALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN 1519
                  L  Q   EG  +   V   +E ++  W  +G  ++ SDRV   +  +   L I 
Sbjct: 2315 -----GLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIE 2369

Query: 1520 EPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLP 1579
            + T  D G Y   +          + LS       Y+                 V+  L 
Sbjct: 2370 DMTKEDAGNYSFTI--------PALGLSTSGRVSVYS---------------VDVITPLK 2406

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
            DV  I+  KA+ L C V       V W  N++ +  DD        G      IN    +
Sbjct: 2407 DVNVIEGTKAV-LECKVSVPDVTSVKWYLNDEQIKPDDRVQ-AIVKGTKQRLVINRTHAS 2464

Query: 1640 DSGKYGLVV 1648
            D G Y L+V
Sbjct: 2465 DEGPYKLIV 2473



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 121/559 (21%), Positives = 206/559 (36%), Gaps = 117/559 (20%)

Query: 1168  EFSWSKDYVSTEDSPRLEVESKGNKT-KMTFKDLGMDDLGIYSCDVTDTDGIASSYL--- 1223
             E +W KD    +++   +     + T ++   +L   D G Y C+++   G + + L   
Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26310

Query: 1224  -------------------IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWM 1264
                                 D++  +  +    E K P       + V  L+   V    
Sbjct: 26311 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDS 26370

Query: 1265  QAE---KLSGNAKVNYIFNE--KEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQ 1319
              A+   K +G  +   I+ +  K I +G KYK+  D+    +E+   K    D G YT  
Sbjct: 26371 VAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEI--HKTDTSDSGLYTCT 26428

Query: 1320  LQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCK 1379
             +++   +  S+  L      K  K+ E Q+              +S + T E   +   K
Sbjct: 26429 VKNSAGSVSSSCKLT----IKAIKDTEAQK--------------VSTQKTSE---ITPQK 26467

Query: 1380  VANIKKETHIVWYKDER----EISVDEKHDFKDGICTLLITEFSKKDAG-------IYEV 1428
              A +++E      + E     E    EK   K+    +LI+E  KK A        ++E 
Sbjct: 26468 KAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEE 26527

Query: 1429  ILKDDRGKDKSRLKLVDEAFKELMME------VCKKIALSATDLKIQSTAEGIQLYSFVT 1482
             I K  +  ++ R     +AF   M        V K     ATD+K               
Sbjct: 26528 ITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVK--------------- 26572

Query: 1483  YYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKG--KYVMELFDGKTGH 1540
                      W  NG  +  S+  + GV+G    L I + +  D+G    + +  +G    
Sbjct: 26573 ---------WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKC 26623

Query: 1541  QKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDP 1600
             Q  + LS +  D           A I++          P    I EG+ +  TC + G+P
Sbjct: 26624 QYDLTLSKELSDAP---------AFISQ----------PRSQNINEGQNVLFTCEISGEP 26664

Query: 1601  PPEVSWLKNEKALASDDHCNLKFEAGRTAY-FTINGVSTADSGKYGLVVKNKYGSETSDF 1659
              PE+ W KN   ++     N+     R  Y   I   S +DSGKY +  KN  G  ++  
Sbjct: 26665 SPEIEWFKNNLPISISS--NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 26722

Query: 1660  TVSVF-IPEEEARMAALES 1677
             ++ V  + EE +R   L +
Sbjct: 26723 SLMVLPLVEEPSREVVLRT 26741



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 91/360 (25%), Positives = 148/360 (41%), Gaps = 39/360 (10%)

Query: 175  EEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEE 234
            E  I  S  +T  K+ +A+  S+A K + + K  T     T  R               +
Sbjct: 785  EASIAGSAIATLQKELSAT--SSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTPD 842

Query: 235  TSEKKSRKVVIREKAERLSLRKTLEET-ETYH---AKLNEDHLLHAP-EFIIKP------ 283
            T + ++   V +E    ++     EE  E  H   AK+ E   + AP E  + P      
Sbjct: 843  TYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSG 902

Query: 284  -RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGC 342
             ++ TV E E+V L C I+G+P P VTWY+    I    +   + I  + G+  L I   
Sbjct: 903  LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSID---FQITFQSGIARLMIREA 959

Query: 343  DFEDTAQYRASAMNVKGEL--SAYASVVVKR----------YKGEFDETRFHAGASTMPL 390
              ED+ ++  SA+N  G +  S Y +V V             K   +E RF      +  
Sbjct: 960  FAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMT 1019

Query: 391  SFGVT--PYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGV 448
               +T    G       +F  K  V    EG ++  GC+V   P     +P + W ++GV
Sbjct: 1020 DTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNP-----KPHVYWKKSGV 1074

Query: 449  PLSPSKWVQTLWSGE--RATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEI 506
            PL+     +  ++ +     L  S    +D G YTI VR  ++ E  ++   + +AD E+
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVR-NKHGETSASASLLEEADYEL 1133



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 63/303 (20%), Positives = 130/303 (42%), Gaps = 23/303 (7%)

Query: 1039  PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1098
             P  P +L   EV+KDS+ L W+PP+  G   +T Y V+ +E   K   +  +     K  
Sbjct: 18702 PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK--AYATITNNCTKTT 18759

Query: 1099  YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD-DDGVISLN 1157
             + ++  L+EG SY FRV A N+ G+G P++   PV     P     V  VD      ++ 
Sbjct: 18760 F-RIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIK 18818

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
             +E  +    S+ +     + T+ S +    ++    + T   L   +  ++     +  G
Sbjct: 18819 WEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKG 18878

Query: 1218  IASSYLIDEEELKRLLALSHEHKFP----TVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
              +    +    + R + +    + P     V  + +L +++  KG+ +           A
Sbjct: 18879 RSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQ-----------A 18927

Query: 1274  KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD--GKATNHSTV 1331
              VN+  + + + E    ++++  +  +  + +++   ED GTY   + +  G  T   T+
Sbjct: 18928 TVNWRKDGQTLKE--TTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITI 18985

Query: 1332  VLV 1334
             +++
Sbjct: 18986 IVL 18988



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 62/233 (26%), Positives = 93/233 (39%), Gaps = 35/233 (15%)

Query: 251   RLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTW 310
             R +++K    T+T         L   PEF +   + T +  ENV+   +I   PEP VTW
Sbjct: 25173 RRTMKKIKRRTDTMRL------LERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTW 25226

Query: 311   YKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
             YK+   I    N  KY  ES  G++ L IN    +D A+Y   A N  GE S  A + V 
Sbjct: 25227 YKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVT 25286

Query: 371   RYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVI 430
              +    D T         P+                F      +  +EG+++    RV  
Sbjct: 25287 LHPPPTDST-------LRPM----------------FKRLLANAECQEGQSVCFEIRVSG 25323

Query: 431   TPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG-ERATLTFSHLNKEDEGLYTI 482
              P      P ++W ++G PLS    ++ +  G +   L       ED G Y +
Sbjct: 25324 IP-----PPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25371



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 110/549 (20%), Positives = 203/549 (36%), Gaps = 91/549 (16%)

Query: 1132 PVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGN 1191
            P V  T+P   + V    ++G  ++  EC+     ++  W K+      S + E+ + G 
Sbjct: 5786 PPVEFTKPLEDQTV----EEGATAV-LECEVSRENAKVKWFKNGTEILKSKKYEIVADGR 5840

Query: 1192 KTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELA 1251
              K+   D   +D+  Y+CD  D     +  ++                 P V     L 
Sbjct: 5841 VRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVP----------------PHVEFLRPLT 5884

Query: 1252 -VEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQD 1310
             +++ EK   RF  + E    NAKV +  +  EI +G KY   I     +  + + K   
Sbjct: 5885 DLQVREKEMARF--ECELSRENAKVKWFKDGAEIKKGKKY--DIISKGAVRILVINKCLL 5940

Query: 1311 EDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTG 1370
            +DE  Y+ +++  + +   TV         L++EA F +               + EV+ 
Sbjct: 5941 DDEAEYSCEVRTARTSGMLTV---------LEEEAVFTK------------NLANIEVSE 5979

Query: 1371 ECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVIL 1430
               + L C+V+  K    ++WYK + EI    +++        ++TE  K+   I    L
Sbjct: 5980 TDTIKLVCEVS--KPGAEVIWYKGDEEIIETGRYE--------ILTEGRKRILVIQNAHL 6029

Query: 1431 KDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKV 1490
             +D G    RL       K  + E+  +      +L+I    EG +     +   E   V
Sbjct: 6030 -EDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEI---LEGEKAEFVCSISKESFPV 6085

Query: 1491 NWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQA 1550
             W  +   +   D+      G++  L + + T  D G YV+ +   +     TV      
Sbjct: 6086 QWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTV------ 6139

Query: 1551 YDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNE 1610
                                + R++  L D   ++E + +   C V      +  W +NE
Sbjct: 6140 ------------------IEKLRIVVPLKD-TRVKEQQEVVFNCEV-NTEGAKAKWFRNE 6179

Query: 1611 KALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEA 1670
            +A+  D    +  +        I      D   Y + + N  G E      ++ + EE+ 
Sbjct: 6180 EAI-FDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG-ENVKSAANLIVEEEDL 6237

Query: 1671 RMAALESLK 1679
            R+  +E LK
Sbjct: 6238 RI--VEPLK 6244



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 62/235 (26%), Positives = 100/235 (42%), Gaps = 13/235 (5%)

Query: 142   SGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQSTASKQ 201
             S RQ+ V+ IT+ EEE   E + + AQR   +S   +   ++S +       +  +   +
Sbjct: 25738 SRRQREVTEITEIEEEY--EISKH-AQRESSSSASRLLRRRRSLSPTYIELMRPVSELIR 25794

Query: 202   STAS-----KQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRK 256
             S        +  T  R  T  R    S    S+ +     E+ +R  +        +  K
Sbjct: 25795 SRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALK 25854

Query: 257   TLEETETYHAKLNEDH--LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQ 314
             T + +E  +  L++    L HAP   ++ RSH V   +N +   ++   P   V WY N 
Sbjct: 25855 TQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNG 25914

Query: 315   VPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
             V +       K    +  G+ TLEI  C  +D+  YRA   N KGE S YA++ V
Sbjct: 25915 VELQ---ESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 105/531 (19%), Positives = 200/531 (37%), Gaps = 98/531 (18%)

Query: 1147 NVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLG 1206
            N++     + +FEC+         W K+ V  E S + ++  +G   ++   +   +D  
Sbjct: 2844 NIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSA 2903

Query: 1207 IYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQA 1266
             Y+  V   D ++++  +    +  +L   +  +  T+  +    V +  +G    W++ 
Sbjct: 2904 EYTF-VCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFE----VTVNYEGISYKWLK- 2957

Query: 1267 EKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKAT 1326
                         N  EI    K +M   + T  + +    +   D   YTF    GKAT
Sbjct: 2958 -------------NGVEIKSTDKCQMRTKKLTHSLNI--RNVHFGDAADYTFVA--GKAT 3000

Query: 1327 NHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKE 1386
            + +T+ +         +  EF++         H  +    +V  +   + +C+V+  + +
Sbjct: 3001 STATLYVEA-------RHIEFRK---------HIKDI---KVLEKKRAMFECEVS--EPD 3039

Query: 1387 THIVWYKDEREISVDEKHDFKDG--ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLV 1444
              + W KD++E+ + ++   +    +  LLI      DAG Y V+     G + S  KL 
Sbjct: 3040 ITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA----GGNVSTAKLF 3095

Query: 1445 DEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVE------DLKVNWSHNGSA 1498
             E                  D++I+S  + +Q+       VE      D+  +W  +G  
Sbjct: 3096 VEG----------------RDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIE 3139

Query: 1499 IRYS--DRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYA 1556
            I +   +R K  V      + I+E   +D G+Y      G+     T+ ++     +   
Sbjct: 3140 INFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA--GRNRSSVTLYVNAPEPPQVLQ 3197

Query: 1557 EFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD 1616
            E Q                      VT+Q GK       + G P P++SW K E+ L++ 
Sbjct: 3198 ELQP---------------------VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTG 3236

Query: 1617 DHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPE 1667
              C    +        I      D+  Y    KN YG  T+  ++SV +PE
Sbjct: 3237 FKCKFLHDGQEYTLLLIEAF-PEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 46/149 (30%), Positives = 67/149 (44%), Gaps = 9/149 (6%)

Query: 637   VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
             VP PP  + V++ +R  V L+W  P   G   I  Y VEKC    E W RV      +  
Sbjct: 24624 VPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ---ARET 24680

Query: 696   RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV-GDKLDIPKAPGKIIPSRNTDTS 754
             R+ + +L    SY FRV   N  G+ +PSE +E T+   DK        ++  +R     
Sbjct: 24681 RYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR----E 24736

Query: 755   VVVSWEESKDAKELVGYYIEASVAGSGKW 783
             V ++       KEL   Y+ A   G G++
Sbjct: 24737 VSMTKASHSSTKELYEKYMIAEDLGRGEF 24765



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 101/468 (21%), Positives = 186/468 (39%), Gaps = 77/468 (16%)

Query: 1073 YFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGP 1132
            +F D  E K K  ++  +++ A++ + +    L +   Y   VR    +G+         
Sbjct: 5909 WFKDGAEIK-KGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLT------- 5960

Query: 1133 VVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNK 1192
            V+ E    TK +  N++     ++   C+   P +E  W K      ++ R E+ ++G K
Sbjct: 5961 VLEEEAVFTKNLA-NIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRK 6019

Query: 1193 TKMTFKDLGMDDLGIYSCDVTD--TDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSEL 1250
              +  ++  ++D G Y+C +    TDG    + +  E + +   L               
Sbjct: 6020 RILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL--------------- 6064

Query: 1251 AVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQD 1310
              EILE  +  F     K S    V +  ++K +  G KY +  D    ++ +    LQD
Sbjct: 6065 --EILEGEKAEFVCSISKES--FPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQD 6120

Query: 1311 EDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTG 1370
               GTY   +   +A  H TV+    +   L+     ++QE                   
Sbjct: 6121 M--GTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQE------------------- 6159

Query: 1371 ECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIYEV 1428
               V+  C+V    +     W+++E  I    K+    KD + TL I +    D   Y V
Sbjct: 6160 ---VVFNCEVNT--EGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNV 6214

Query: 1429 ILKDDRGKD-KSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVED 1487
             L + RG++ KS   L+ E     ++E  K I             E ++  S VT++ + 
Sbjct: 6215 SLTNHRGENVKSAANLIVEEEDLRIVEPLKDI-------------ETMEKKS-VTFWCKV 6260

Query: 1488 LKVN----WSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
             ++N    W+ NG  + + +RV   V   +  L I +    D+G+Y++
Sbjct: 6261 NRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIV 6308



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 14/165 (8%)

Query: 1038  VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
             VP PP  +K S+V +DS+ L W  P   G + +T Y V+  +     ++W  + +A  + 
Sbjct: 24624 VPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVE--KCATTAERWLRVGQA--RE 24679

Query: 1098  VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLN 1157
                 V  L    SY FRV A N+ G+ KPS+ + P + +     K   +N D++   +  
Sbjct: 24680 TRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE---DKTRAMNYDEEVDETRE 24736

Query: 1158  FECDKMTPKSEFSWSKDYVSTEDSPRLE-------VESKGNKTKM 1195
                 K +  S     + Y+  ED  R E       VE+   KT M
Sbjct: 24737 VSMTKASHSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYM 24781



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 91/399 (22%), Positives = 155/399 (38%), Gaps = 46/399 (11%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            FEC+   P     W KD    + + R++++ +    ++      M D G Y+  V     
Sbjct: 3031 FECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYT--VVAGGN 3088

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQ--VRFWMQAEKLSGNAKV 1275
            ++++ L  E    R+ ++  E             V+++EK +  V F +  + +  +   
Sbjct: 3089 VSTAKLFVEGRDVRIRSIKKE-------------VQVIEKQRAVVEFEVNEDDVDAHWYK 3135

Query: 1276 NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVG 1335
            + I    ++ E  KY   ++R   I  MF+ + +  D G YTF        N S+V L  
Sbjct: 3136 DGIEINFQVQERHKYV--VERR--IHRMFISETRQSDAGEYTFVA----GRNRSSVTLYV 3187

Query: 1336 DVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDE 1395
            +  +  Q   E Q       +   F                 C V + + +  I WYK+E
Sbjct: 3188 NAPEPPQVLQELQPVTVQSGKPARF-----------------CAVISGRPQPKISWYKEE 3230

Query: 1396 REISVDEKHDF-KDGI-CTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1453
            + +S   K  F  DG   TLL+ E   +DA +Y    K+D G   +   L  E  + +  
Sbjct: 3231 QLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSP 3290

Query: 1454 EVCKKIALSA--TDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTG 1511
            +    +   A  T L+   T+EG            DLKV+W      I+ S   +     
Sbjct: 3291 DQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFE 3350

Query: 1512 EQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQA 1550
            +   L+I E  P D+G Y     +       T +LS +A
Sbjct: 3351 DTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3389



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 36/116 (31%), Positives = 59/116 (50%), Gaps = 7/116 (6%)

Query: 1036 IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKE--DQWRGLNEA 1093
            I +PGP   +K S++ K S  L W+PP   G TP+  Y ++ +EA  +       G N+ 
Sbjct: 7980 IGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKL 8039

Query: 1094 AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD 1149
            +       V+ L     Y FRV+A+N+ G G+  +L  PV+A+      +  V+V+
Sbjct: 8040 S-----WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8090



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 96/288 (33%)

Query: 1489  KVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY--VMELFDGKTGHQKTVDL 1546
             +V W HNG  ++ S ++    T   + L+I +   +D G Y  V   + G+     T+D+
Sbjct: 25907 EVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966

Query: 1547  SGQAYD----------------------EAYA--EFQR---------------------- 1560
             +G  Y                       EAYA   F++                      
Sbjct: 25967 TGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRE 26026

Query: 1561  ------------LKQAAIAEKN--------------RARVLGGLPDVVTIQEGKALNLTC 1594
                         +K AA+ EK+               AR+L   P  +T+ EG++   +C
Sbjct: 26027 SLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTK-PRSMTVYEGESARFSC 26085

Query: 1595  NVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAY---FTINGVSTADSGKYGLVVKNK 1651
             +  G+P P V+WL+  + L++    + + +   T Y   F I+ V  +D G Y +VV+N 
Sbjct: 26086 DTDGEPVPTVTWLRKGQVLST----SARHQVTTTKYKSTFEISSVQASDEGNYSVVVENS 26141

Query: 1652  YGSETSDFTVSV--------------FIPEEEARMAALESLKGGKKAK 1685
              G + ++FT+++               +   E R+ + E++K  K+ K
Sbjct: 26142 EGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVK 26189



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 57/235 (24%), Positives = 100/235 (42%), Gaps = 27/235 (11%)

Query: 1466  LKIQSTAEGIQLYSFVTYYVEDLK-VNWSHNGSAIRYSDRVKTGVTGEQIW-LQINEPTP 1523
             LK +++ E  +L   V   V   K V W  +G  ++ +   +   + +  + L+IN  T 
Sbjct: 26227 LKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 26286

Query: 1524  NDKGKYVMELFDGKTGHQKT-VDLSGQAY----------DEAYAEFQRLKQAAIAEKNRA 1572
             +D+G+YV E+  G+ G  KT +   GQA+           E     Q+  ++ +  K   
Sbjct: 26287 SDQGEYVCEI-SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP 26345

Query: 1573  R----------VLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLK 1622
             +          ++ GL D  T+             G+P P   W K+ KA+       L 
Sbjct: 26346 KAPEPISSKPVIVTGLQD-TTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS 26404

Query: 1623  FEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV-FIPEEEARMAALE 1676
              + G   +  I+   T+DSG Y   VKN  GS +S   +++  I + EA+  + +
Sbjct: 26405 EDKG-GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQ 26458



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 93/428 (21%), Positives = 159/428 (37%), Gaps = 58/428 (13%)

Query: 1039  PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1098
             PGP   L  S V ++   L W  P   G   +T Y V+ +E       W  +        
Sbjct: 22644 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLN--WVIVEGECPTLS 22701

Query: 1099  YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVA--------------ETRPGTKEV 1144
             Y+  R +K    Y+FRVRA+N+ G G P + + P+VA              E   G + +
Sbjct: 22702 YVVTRLIKNN-EYIFRVRAVNKYGPGVPVE-SEPIVARNSFTIPSPPGIPEEVGTGKEHI 22759

Query: 1145  VVN----VDDDGVISLNFECDKMTPKSEFSWS---KDYVSTEDSPRLEVESKGNKTKMTF 1197
             ++       D G    N+  DK   KS   W+   KDYV  +            + K+T 
Sbjct: 22760 IIQWTKPESDGGNEISNYLVDKREKKS-LRWTRVNKDYVVYD-----------TRLKVTS 22807

Query: 1198  KDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEK 1257
                G D    Y   VT  +   +S   +  E    ++   E  +   P  +   V+  + 
Sbjct: 22808 LMEGCD----YQFRVTAVNAAGNS---EPSEASNFISC-REPSYTPGPPSAPRVVDTTKH 22859

Query: 1258  GQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
                  W +     G   V Y+   +E      Y++H +      E  +  L+   +  Y+
Sbjct: 22860 SISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK--YS 22917

Query: 1318  FQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLK 1377
             F++           V V  + +  +  AE +  E I        + L   VT      L+
Sbjct: 22918 FRV---------AAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLR 22968

Query: 1378  CKVANIKKETHIV-WYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGK 1436
               V+   +   ++ W K   +++     D  +    L++ + ++ DAG Y +  ++  GK
Sbjct: 22969 LMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGK 23028

Query: 1437  DKSRLKLV 1444
              KS   LV
Sbjct: 23029 -KSATVLV 23035



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 100/495 (20%), Positives = 186/495 (37%), Gaps = 92/495 (18%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            FEC+     ++  W KD    +   + ++ SKG    +      +DD   YSC+V     
Sbjct: 5896 FECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTART 5955

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
                 +++EE                V  K+   +E+ E   ++   +  K    A+V +
Sbjct: 5956 SGMLTVLEEE---------------AVFTKNLANIEVSETDTIKLVCEVSK--PGAEVIW 5998

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQL----QDGKATNHSTVVL 1333
               ++EI E  +Y++  +    I  + ++    ED G Y  +L     DGK   H     
Sbjct: 5999 YKGDEEIIETGRYEILTEGRKRI--LVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAA- 6055

Query: 1334 VGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYK 1393
                             E+I K  P  +E L  E          C ++  K+   + W +
Sbjct: 6056 -----------------EFISK--PQNLEILEGE-----KAEFVCSIS--KESFPVQWKR 6089

Query: 1394 DEREISVDEKHD-FKDG-ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKEL 1451
            D++ +   +K+D   DG    L++ + + +D G Y V++   R    + L ++++     
Sbjct: 6090 DDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARA--AAHLTVIEKL---- 6143

Query: 1452 MMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTG 1511
                  +I +   D +++   E +      T   E  K  W  N  AI  S +       
Sbjct: 6144 ------RIVVPLKDTRVKEQQEVVFNCEVNT---EGAKAKWFRNEEAIFDSSKYIILQKD 6194

Query: 1512 EQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAA--IAEK 1569
                L+I +   +D+  Y + L    T H+                 + +K AA  I E+
Sbjct: 6195 LVYTLRIRDAHLDDQANYNVSL----TNHRG----------------ENVKSAANLIVEE 6234

Query: 1570 NRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTA 1629
               R++  L D+ T+ E K++   C V       + W KN + +  D+  + + +  +  
Sbjct: 6235 EDLRIVEPLKDIETM-EKKSVTFWCKV-NRLNVTLKWTKNGEEVPFDNRVSYRVDKYK-H 6291

Query: 1630 YFTINGVSTADSGKY 1644
              TI      D G+Y
Sbjct: 6292 MLTIKDCGFPDEGEY 6306



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             +P+ +TI+ GK L +  +V+G P P   W K E  + +  H  +  +A  ++   I  V+
Sbjct: 12407 MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV-HKADSSSILIIKDVT 12465

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG Y L  +N  G++T    V V
Sbjct: 12466 RKDSGYYSLTAENSSGTDTQKIKVVV 12491



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 44/192 (22%), Positives = 83/192 (43%), Gaps = 30/192 (15%)

Query: 180   TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
             T   + +S + T+  ++++S +   S Q T +R+S +S +   S +  SA  +E++ E  
Sbjct: 25994 TEAYAVSSFKKTSEMEASSSVREVKS-QMTETRESLSSYEHSASAEMKSAALEEKSLE-- 26050

Query: 240   SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
                    EK+    ++ TL                 A   + KPRS TV+E E+ +  C 
Sbjct: 26051 -------EKSTTRKIKTTL-----------------AARILTKPRSMTVYEGESARFSCD 26086

Query: 300   IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
               G P P VTW +    ++  A   ++ + +     T EI+     D   Y     N +G
Sbjct: 26087 TDGEPVPTVTWLRKGQVLSTSA---RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEG 26143

Query: 360   ELSAYASVVVKR 371
             +  A  ++ +++
Sbjct: 26144 KQEAEFTLTIQK 26155



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 32/84 (38%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D +TI+ G+A  LT    G P P+VSW K+E  +  DD  ++K      A   I     +
Sbjct: 10329 DKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK-AKRS 10387

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             DSGKY +VV+N  GS      V+V
Sbjct: 10388 DSGKYCVVVENSTGSRKGFCQVNV 10411



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 47/166 (28%), Positives = 72/166 (43%), Gaps = 9/166 (5%)

Query: 1503  DRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQ--- 1559
             +R      G+  WL+ N    +D    V  L +G T   + +  +        +E     
Sbjct: 22479 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22538

Query: 1560  --RLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDD 1617
               R + A    +  AR+ G   D+VTI+ G  L L   V G P P++ W K +K L   +
Sbjct: 22539 TCRDEYAPPKAELDARLHG---DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCE 22595

Query: 1618  HCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               +L++  G+ A   I     +DSGKY L VKN  G++     V V
Sbjct: 22596 KVSLQY-TGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV 22640



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 78/375 (20%), Positives = 132/375 (35%), Gaps = 84/375 (22%)

Query: 184  STASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKV 243
            +T +K+    K++         ++S   R     R      +A +A++ +   + +S + 
Sbjct: 1924 TTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEE 1983

Query: 244  VIREKAERLSLRKTLEETETYHAKLNEDHLL----------------HAPEFIIKPRSHT 287
            ++R+  + L L  T E TE     L E+  +                 AP+   + +S T
Sbjct: 1984 LLRKTKDEL-LHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQT 2042

Query: 288  VWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDT 347
            V +  +      + G P+P   WYKN V I        Y  E    +  L I     ED+
Sbjct: 2043 VGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPED--NVCELVIRDVTAEDS 2100

Query: 348  AQYRASAMNVKGELSAYASVVVKRYK-------------GEFDETRFHAGASTMPLSFGV 394
            A     A+N+ GE S++A ++V+  +              E D        ++ P    V
Sbjct: 2101 ASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPF---V 2157

Query: 395  TPYGYASRFEIHFDDKFDVSFGR-----------------------EGETMSLGCRVVIT 431
                Y    E+H  DK+ +   R                       E E +    ++++ 
Sbjct: 2158 KVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVE 2217

Query: 432  PEIKHFQPEIQ------------------------WYRNGVPL-SPSKWVQTLWSGERAT 466
              +  F  E+Q                        WY N V L S  K+  T   G R  
Sbjct: 2218 GAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRG-RQN 2276

Query: 467  LTFSHLNKEDEGLYT 481
            LT   + KED+G Y+
Sbjct: 2277 LTVKDVTKEDQGEYS 2291



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 99/522 (18%), Positives = 185/522 (35%), Gaps = 87/522 (16%)

Query: 1165 PKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLI 1224
            P+ + SW K+        + +    G +  +   +   +D  +Y+C+  +  G+A++   
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279

Query: 1225 DEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQ-VRFWMQAEKLSGNAKVNYIFNEKE 1283
               E+  +++   E       + + L   +  +GQ  RF  Q      + KV++   +K+
Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARF--QCRVSGTDLKVSWYSKDKK 3337

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGD-----VF 1338
            I     ++M    +T  +E+   +   EDEGTYTF   +      ST  L  +     + 
Sbjct: 3338 IKPSRFFRMTQFEDTYQLEI--AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILH 3395

Query: 1339 KKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREI 1398
            +++++E E + +E+          +LS E  G     L      + K    +    E  +
Sbjct: 3396 ERIEQEIEMEMKEFSS-------SFLSAEEEG-----LHSAELQLSKINETLELLSESPV 3443

Query: 1399 SVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKK 1458
               +    K+G   + I E S  D  + +V                              
Sbjct: 3444 YPTKFDSEKEGTGPIFIKEVSNADISMGDV------------------------------ 3473

Query: 1459 IALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQI 1518
              LS T + I                    K+ W  NG  +  S   K    G+   L I
Sbjct: 3474 ATLSVTVIGIPKP-----------------KIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516

Query: 1519 NEPTPNDKGKYVMELFD--GKT--GHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARV 1574
                  D+G+Y     +  GKT       ++  G+ + +   E      +A+A K+  ++
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE------SAVA-KSLEKL 3569

Query: 1575 LGGLP-------DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGR 1627
             G  P         +   +G        V G+P P V+W K  K L +  +  +      
Sbjct: 3570 GGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNG 3629

Query: 1628 TAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEE 1669
            +  F +N     DSG Y    +N  G  T    + V + + +
Sbjct: 3630 SGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTD 3671



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 59/299 (19%), Positives = 114/299 (38%), Gaps = 36/299 (12%)

Query: 1373  NVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDG--ICTLLITEFSKKDAGIYEVIL 1430
             NVL  C+++  +    I W+K+   IS+           + +L I   S  D+G Y +  
Sbjct: 26653 NVLFTCEISG-EPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKA 26711

Query: 1431  KDDRGKDKSR-----LKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYV 1485
             K+ RG+  +      L LV+E  +E+++          T L+   +++ +Q+ +      
Sbjct: 26712 KNFRGQCSATASLMVLPLVEEPSREVVLRTS-----GDTSLQGSFSSQSVQMSAS----- 26761

Query: 1486  EDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVD 1545
                        S   +S    + +T  +      +   + +  +V        G      
Sbjct: 26762 -------KQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQ 26814

Query: 1546  LSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVS 1605
             L             ++ +A I  +     +  LP  ++I EGK L + C   G+P PEV+
Sbjct: 26815 LESST--------SKMLKAGI--RGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVT 26864

Query: 1606  WLKNEKALASDDHCNLKFE-AGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
             W    + + S +      E         I  V   D G Y L + N++GS+++   + +
Sbjct: 26865 WSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 20/157 (12%)

Query: 217  SRQS-VVSKQATSALQQEETSEK---KSRKVVIREKAERLSLRKTLEETETYHAKLNEDH 272
            SR S +++ +AT+    + TS     K  K ++ E+++    RK L+  E      +E  
Sbjct: 1723 SRDSGIITCRATNKYGTDHTSATLIVKDEKSLV-EESQLPEGRKGLQRIEELERMAHEGA 1781

Query: 273  LL---------HAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANP 323
            L            P+ ++ P    V E E  +  C + G+P+P+V WY N   I      
Sbjct: 1782 LTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKR- 1840

Query: 324  GKYIIESRY-GMHTLEINGCDFEDTAQYRASAMNVKG 359
                   RY G+H L+I  C   DT + + +A N +G
Sbjct: 1841 ----FRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEG 1873



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 93/463 (20%), Positives = 166/463 (35%), Gaps = 72/463 (15%)

Query: 1114 RVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSK 1173
            RV A+  +   K + L G        G  +    V+ D VI    +C+     +   W K
Sbjct: 5502 RVEAMGMSSEAKLTVLEGDPYFT---GKLQDYTGVEKDEVI---LQCEISKADAPVKWFK 5555

Query: 1174 DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLL 1233
            D    + S    +++ G K  +  K     D+G Y+CD   TD  +    I++ E+K + 
Sbjct: 5556 DGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD-CGTDKTSGKLDIEDREIKLVR 5614

Query: 1234 ALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMH 1293
             L               +VE++E    RF  + E    +   N+    + + + P     
Sbjct: 5615 PLH--------------SVEVMETETARF--ETEISEDDIHANWKLKGEALLQTP--DCE 5656

Query: 1294 IDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTV-VLVGDVFKKLQKEAEFQRQEW 1352
            I     I  + +   + +  G   FQ  + K++ H  V   V  + + L+          
Sbjct: 5657 IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVT------- 5709

Query: 1353 IRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICT 1412
                           VT        C+++   ++  + WY   +++   +K         
Sbjct: 5710 ---------------VTAGETATFDCELS--YEDIPVEWYLKGKKLEPSDK--------- 5743

Query: 1413 LLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSAT-DLKIQST 1471
                   + +  ++ + L+D + +D   ++L  + FK       K+  +  T  L+ Q+ 
Sbjct: 5744 ----VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTV 5799

Query: 1472 AEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVM 1531
             EG           E+ KV W  NG+ I  S + +    G    L I++ TP D   Y  
Sbjct: 5800 EEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 5859

Query: 1532 ELFDGKTGHQKTVDLSGQAYDEAYAEFQR-LKQAAIAEKNRAR 1573
            +  D KT     V          + EF R L    + EK  AR
Sbjct: 5860 DAKDFKTSCNLNV-------VPPHVEFLRPLTDLQVREKEMAR 5895



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 96/436 (22%), Positives = 168/436 (38%), Gaps = 62/436 (14%)

Query: 1100 LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFE 1159
            L +R +    S    V+AIN AG             +    T+E+   V  +      FE
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFE 2149

Query: 1160 CDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIA 1219
            C+   P  +  W KD +   +  +  + S      ++   +   D   YSC + + + + 
Sbjct: 2150 CETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVK 2209

Query: 1220 SSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILE--KGQVRFWMQAEKLSGNAKVNY 1277
            ++         +L+      +F    VK    +E+ E   G++   +  E + G     +
Sbjct: 2210 TT--------AKLIVEGAVVEF----VKELQDIEVPESYSGELECIVSPENIEG----KW 2253

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDV 1337
              N+ E+    KY   I    G   + ++ +  ED+G Y+F + DGK T           
Sbjct: 2254 YHNDVELKSNGKYT--ITSRRGRQNLTVKDVTKEDQGEYSFVI-DGKKTT---------- 2300

Query: 1338 FKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVL-LKCKVANIKKETHIVWYKDER 1396
              KL+          ++ +    ++ LS +   E +++ L+ KV+   +    VW KD +
Sbjct: 2301 -CKLK----------MKPRPIAILQGLSDQKVCEGDIVQLEVKVS--LESVEGVWMKDGQ 2347

Query: 1397 EIS-VDEKHDFKDGIC-TLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMME 1454
            E+   D  H   D     LLI + +K+DAG Y   +         R+ +         ++
Sbjct: 2348 EVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-------VD 2400

Query: 1455 VCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDL-KVNWSHNGSAIRYSDRVKTGVTGEQ 1513
            V        T LK  +  EG +        V D+  V W  N   I+  DRV+  V G +
Sbjct: 2401 V-------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTK 2453

Query: 1514 IWLQINEPTPNDKGKY 1529
              L IN    +D+G Y
Sbjct: 2454 QRLVINRTHASDEGPY 2469



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 115/564 (20%), Positives = 203/564 (35%), Gaps = 88/564 (15%)

Query: 1090 LNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD 1149
            L E   + + ++   L++  +Y  R+ +    G  K  +LA   ++  +P   E++    
Sbjct: 6014 LTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFIS--KPQNLEILEGEK 6071

Query: 1150 DDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYS 1209
             + V S++ E   +       W +D  + E   + +V + G K  +  KD  + D+G Y 
Sbjct: 6072 AEFVCSISKESFPV------QWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYV 6125

Query: 1210 CDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKL 1269
              V      A   +I++  +              VP+K      + E+ +V F    E  
Sbjct: 6126 VMVGAARAAAHLTVIEKLRI-------------VVPLKD---TRVKEQQEVVF--NCEVN 6167

Query: 1270 SGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHS 1329
            +  AK  +  NE+ IF+  KY   I +   +  + +     +D+  Y   L + +  N  
Sbjct: 6168 TEGAKAKWFRNEEAIFDSSKYI--ILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVK 6225

Query: 1330 TVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHI 1389
            +   +    + L+     +  E + K+   F     W      NV LK            
Sbjct: 6226 SAANLIVEEEDLRIVEPLKDIETMEKKSVTF-----WCKVNRLNVTLK------------ 6268

Query: 1390 VWYKDEREISVDEKHDFKDGICTLLIT--EFSKKDAGIYEVILKDDRGKDKSRLKLVDEA 1447
             W K+  E+  D +  ++      ++T  +    D G Y V      G+DKS  +L    
Sbjct: 6269 -WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTA----GQDKSVAEL---- 6319

Query: 1448 FKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKT 1507
               L++E   +      D   Q+  E            E   V W  NG  I+   + K 
Sbjct: 6320 ---LIIEAPTEFVEHLED---QTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKF 6373

Query: 1508 GVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIA 1567
               G    L I +   +D+ +Y   + D K+  +  V       +E   E  R  Q  + 
Sbjct: 6374 EKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFV-------EEIPVEIIRPPQDILE 6426

Query: 1568 EKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGR 1627
                        DVV + E   LN           EV WL+N   +   D   +  E G+
Sbjct: 6427 APG--------ADVVFLAE---LN-------KDKVEVQWLRNNMVVVQGDKHQMMSE-GK 6467

Query: 1628 TAYFTINGVSTADSGKYGLVVKNK 1651
                 I  +   D G+Y  + K+K
Sbjct: 6468 IHRLQICDIKPRDQGEYRFIAKDK 6491



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 44/200 (22%), Positives = 83/200 (41%), Gaps = 11/200 (5%)

Query: 1484  YVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKT 1543
             Y +  +V W      +  S++ +         L + + T  D G Y  ++ +        
Sbjct: 25097 YDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSY 25156

Query: 1544  VDLSGQAYDEAYAEFQRLKQAAIAEK-NRARVLGGLPDVV------TIQEGKALNLTCNV 1596
              +L  +   E Y  + R     I  + +  R+L   P+        T   G+ +     +
Sbjct: 25157 AELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTI 25216

Query: 1597  WGDPPPEVSWLKN-EKALASDDHCNLKFEAGRTAY-FTINGVSTADSGKYGLVVKNKYGS 1654
                P P V+W K+ +K    D+     FE+ +  Y  TIN V+T D  +Y +V +NKYG 
Sbjct: 25217 TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE 25276

Query: 1655  ET--SDFTVSVFIPEEEARM 1672
             ++  +  TV++  P  ++ +
Sbjct: 25277 DSCKAKLTVTLHPPPTDSTL 25296



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 49/207 (23%), Positives = 79/207 (38%), Gaps = 35/207 (16%)

Query: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
           AP F    +S  V E         I+G+P P V+W+++   I+    PG  I  S  G  
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSD-GRA 63

Query: 336 TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVT 395
            L I      ++ +Y   A N  G+ ++ A ++VK              A T P      
Sbjct: 64  KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK--------------AETAP------ 103

Query: 396 PYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKW 455
                     +F  +      R+G  + L  RV   P      P +++YR+G  +  S  
Sbjct: 104 ---------PNFVQRLQSMTVRQGSQVRLQVRVTGIP-----TPVVKFYRDGAEIQSSLD 149

Query: 456 VQTLWSGERATLTFSHLNKEDEGLYTI 482
            Q    G+  +L  +    ED G Y++
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSV 176



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 2/90 (2%)

Query: 1575  LGGLPDVVTI-QEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTI 1633
             L GLPD+  + +E     L   + G P P VSW K E  LA+D   +++  A  T    +
Sbjct: 13487 LKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTT-LIV 13545

Query: 1634  NGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
                  +D+GKY + +KN  G++    ++ V
Sbjct: 13546 YDCQKSDAGKYTITLKNVAGTKEGTISIKV 13575



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 112/499 (22%), Positives = 178/499 (35%), Gaps = 92/499 (18%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            FEC+       F W K         R E+   G K  M  K    +D   Y  +  D   
Sbjct: 5362 FECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH- 5420

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
             +   +I+   LK L            P+K    V   EK    F    E    N +V +
Sbjct: 5421 TSGKLIIEGIRLKFL-----------TPLKD---VTAKEKESAVF--TVELSHDNIRVKW 5464

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDV 1337
              N++ +       M  +  T  I    + L  +D      +   G ++     VL GD 
Sbjct: 5465 FKNDQRLHTTRSVSMQDEGKTHSIT--FKDLSIDDTSQIRVEAM-GMSSEAKLTVLEGDP 5521

Query: 1338 F--KKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDE 1395
            +   KLQ     ++ E                      V+L+C+++  K +  + W+KD 
Sbjct: 5522 YFTGKLQDYTGVEKDE----------------------VILQCEIS--KADAPVKWFKDG 5557

Query: 1396 REISVDEKHDFK-DGICTLLITEFS-KKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1453
            +EI   +    K DG   +LI + + K D G Y      D G DK+  KL D   +E+  
Sbjct: 5558 KEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKL-DIEDREI-- 5610

Query: 1454 EVCKKIALSATDLKIQSTAEGIQLYSFVTYYVE-DLKVNWSHNGSAIRYSDRVKTGVTGE 1512
                K+      +++  T    +   F T   E D+  NW   G A+             
Sbjct: 5611 ----KLVRPLHSVEVMET----ETARFETEISEDDIHANWKLKGEAL------------- 5649

Query: 1513 QIWLQINEPTPNDKGK-YVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR 1571
               LQ  +    ++GK + + L + +      VD   QA +   +   R+K   I     
Sbjct: 5650 ---LQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANVKSSAHLRVKPRVIG---- 5700

Query: 1572 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYF 1631
              +L  L D VT+  G+     C +  +  P V W    K L   D    + E G+    
Sbjct: 5701 --LLRPLKD-VTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSE-GKVHTL 5755

Query: 1632 TINGVSTADSGKYGLVVKN 1650
            T+  V   D+G+  L  K+
Sbjct: 5756 TLRDVKLEDAGEVQLTAKD 5774



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 2/95 (2%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             V  + G+ + +     G PPP V+W K+EK L SD   +++     ++  TI  V+  D+
Sbjct: 20784 VIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDT 20842

Query: 1642  GKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALE 1676
             GKY L ++N  G E    TVSV + +  A    L+
Sbjct: 20843 GKYILTIENGVG-EPKSSTVSVKVLDTPAACQKLQ 20876



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 34/122 (27%), Positives = 61/122 (50%), Gaps = 7/122 (5%)

Query: 1544  VDLSGQA-YDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPP 1602
             V++ G + Y E+ AE + +++  I +   A     L   VTI+ G +L L  +V G PPP
Sbjct: 22923 VNVKGMSEYSESIAEIEPVERIEIPDLELA---DDLKKTVTIRAGASLRLMVSVSGRPPP 22979

Query: 1603  EVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVS 1662
              ++W K    LAS    +        +   ++ V+  D+GKY +  +N+ G +++   V 
Sbjct: 22980 VITWSKQGIDLASRAIID---TTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 23036

Query: 1663  VF 1664
             V+
Sbjct: 23037 VY 23038



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 152/790 (19%), Positives = 286/790 (36%), Gaps = 153/790 (19%)

Query: 997  KISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLV 1056
            KIS  K    Y+  +A   +A L     +S     ++ T +V  P  ++K SE R     
Sbjct: 774  KISVPKTEHGYEASIAGSAIATL--QKELSATSSAQKITKSVKAP--TVKPSETR----- 824

Query: 1057 LQWKPPVHSGRTPVTGY-FVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRV 1115
                  V +  TP+  + F D  +    E       E  +      VR  +  V +    
Sbjct: 825  ------VRAEPTPLPQFPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREA 878

Query: 1116 RAINQAGVGKPSDLAGPVVAETR-PGTKEVVVNVDDDGVISLNFECD-KMTPKSEFSWSK 1173
            +    A V  P ++  PV   T   G K V V   +    S+  EC     P    +W +
Sbjct: 879  KVTETARVPAPVEI--PVTPPTLVSGLKNVTVIEGE----SVTLECHISGYPSPTVTWYR 932

Query: 1174 DYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASS--YL---IDEE- 1227
            +    E S   ++  +    ++  ++   +D G ++C   +  G  S+  YL   + EE 
Sbjct: 933  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF 992

Query: 1228 -------------ELKRLL----------ALSHEHKFPTVP-----VKSELAVEILEKGQ 1259
                         E KR +          +L+ E   P  P     +   +  +++E G 
Sbjct: 993  EKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGS 1052

Query: 1260 VRFWMQAEKLSGNAKVNYIFNEKEI--FEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
            V F  Q   + GN K +  + +  +    G +YK+  ++ TG  ++ +     +D G YT
Sbjct: 1053 VVFGCQ---VGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYT 1109

Query: 1318 FQLQDGKATNHSTVVLVGD----VFKKLQKEAEFQRQEWIRKQGPHFVE------YLSWE 1367
              +++      ++  L+ +    +  K Q+E  +Q Q     Q P   E      Y  +E
Sbjct: 1110 IVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYE 1169

Query: 1368 VTGECN-VLLKCKVANIKKETHIV-WYKDEREISVDEKHDFKDGICTLLITEFSKKDAGI 1425
               E    L++ K+A   K+T +V  Y +++E  +     F++ +   +     K     
Sbjct: 1170 KEYEKEQALIRKKMA---KDTVVVRTYVEDQEFHISS---FEERLIKEIEYRIIKTTL-- 1221

Query: 1426 YEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQS----TAEGIQLYSFV 1481
             E +L++D G++K  + + +    E           S  D +I++       G+  +  +
Sbjct: 1222 -EELLEED-GEEKMAVDISESEAVE-----------SGFDSRIKNYRILEGMGVTFHCKM 1268

Query: 1482 TYYVEDLKVNWSHNGSAIRYSDRVKTGVTGE-QIWLQINEPTPNDKGKYVM--------E 1532
            + Y    K+ W  +G  I++ +R +     + +  L+I    P D+G Y           
Sbjct: 1269 SGYPLP-KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNA 1327

Query: 1533 LFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR--------------------- 1571
            +  GK   +    L    Y        R++  +    +R                     
Sbjct: 1328 ICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMS 1387

Query: 1572 -ARVLGGL---------------------PDVVTIQEGKALNLTCNVWGDPPPEVSWLKN 1609
             AR+  G                      P      EG+       V G P PE  W  +
Sbjct: 1388 PARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHD 1447

Query: 1610 EKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEE 1669
             + + +D    +  +   T    I   + +DSG++ +V +N+ G  +    ++V   E +
Sbjct: 1448 GQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQ 1507

Query: 1670 ARMAALESLK 1679
             +   +E LK
Sbjct: 1508 VKPMFVEKLK 1517



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 41/205 (20%), Positives = 77/205 (37%), Gaps = 33/205 (16%)

Query: 1358  PHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFK---DGICTLL 1414
             P   ++L  E + E   L     +++ +   + WYKD +++  +    F    DG   L 
Sbjct: 26221 PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 26280

Query: 1415  ITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTA-- 1472
             I   ++ D G Y   +  + G  K+ L+ + +AFK +  +V K      +D K   +   
Sbjct: 26281 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVT 26340

Query: 1473  --------EGIQLYSFVTYYVEDLKVN--------------------WSHNGSAIRYSDR 1504
                     E I     +   ++D  V+                    W+ +G AI    +
Sbjct: 26341 RKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGK 26400

Query: 1505  VKTGVTGEQIWLQINEPTPNDKGKY 1529
              K        +L+I++   +D G Y
Sbjct: 26401 YKLSEDKGGFFLEIHKTDTSDSGLY 26425



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 64/306 (20%), Positives = 122/306 (39%), Gaps = 34/306 (11%)

Query: 184   STASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKV 243
             S++ K T  + + T +++ +  K S  + Q  A  Q  +S++A  + + + +  K   K+
Sbjct: 26437 SSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKL 26496

Query: 244   VIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGW 303
              ++E+A ++ +    EE +   A   E  ++H  E I K    T    E V+ H  I   
Sbjct: 26497 ALKEEASKVLIS---EEVKKSAATSLEKSIVH--EEITK----TSQASEEVRTHAEIKA- 26546

Query: 304   PEPRVTWYKNQVPINVHANPGKYIIESRYGMHT---LEINGCDFEDTAQYRASAMNVKGE 360
                    +  Q+ IN      + ++++     T     +NG +  ++ +YR         
Sbjct: 26547 -------FSTQMSIN---EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYG------- 26589

Query: 361   LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGE 420
             +S     +  +     DE      + T     G+    Y         D          +
Sbjct: 26590 VSGSDQTLTIKQASHRDEGILTCISKTKE---GIVKCQYDLTLSKELSDAPAFISQPRSQ 26646

Query: 421   TMSLGCRVVITPEIK-HFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 479
              ++ G  V+ T EI     PEI+W++N +P+S S  V    S    +L   + +  D G 
Sbjct: 26647 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26706

Query: 480   YTIRVR 485
             YTI+ +
Sbjct: 26707 YTIKAK 26712



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 46/190 (24%), Positives = 78/190 (41%), Gaps = 28/190 (14%)

Query: 1492 WSHNGSAI--RYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQ 1549
            W H+G  I   Y+ +V     G Q  L I   TP+D G++ +   +       +V L+ +
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDGTQS-LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1502

Query: 1550 AYDEAYAEF--QRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWL 1607
            A +        ++LK                   V I+EG  L +     G+P P++ WL
Sbjct: 1503 AVEHQVKPMFVEKLKN------------------VNIKEGSRLEMKVRATGNPNPDIVWL 1544

Query: 1608 KNEKALASDDHCNLKFEAGR-TAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFI- 1665
            KN   +    +  ++ E  +  A   I+   + DS  Y     NK G +T+   V+V + 
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604

Query: 1666 ---PEEEARM 1672
               PE E ++
Sbjct: 1605 FAEPEPERKL 1614



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 5/91 (5%)

Query: 1582 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD--DHCNLKFEAGRTAYFTINGVSTA 1639
            V + EG       ++ G P PEVSW ++ + +++       + F  GR A  TI  V+ A
Sbjct: 15   VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR-AKLTIPAVTKA 73

Query: 1640 DSGKYGLVVKNKYGSETSDFTVSVFIPEEEA 1670
            +SG+Y L   N  G  TS  T  + +  E A
Sbjct: 74   NSGRYSLKATNGSGQATS--TAELLVKAETA 102



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             DV+T++ G+ + +   V G P P+++W K  K L  +   +L  +  R     I     A
Sbjct: 11419 DVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE-LQIKEAVRA 11477

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             D GKY +  KN  G       V+V
Sbjct: 11478 DHGKYIISAKNSSGHAQGSAIVNV 11501



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  VV ++    L L   + G P PEV W K E  L   D   ++  +  T    I+ V+
Sbjct: 18616 LRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT--DRAQIEVTSSFTM-LVIDNVT 18672

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG+Y L ++N  GS+T+   V V
Sbjct: 18673 RFDSGRYNLTLENNSGSKTAFVNVRV 18698



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 56/255 (21%), Positives = 97/255 (38%), Gaps = 41/255 (16%)

Query: 238  KKSRKVVIREKAERLSLRKTLEETE---TYHAKLNEDHLL------HAPEFIIKPRSHTV 288
            ++  K V+  +  R+ + +T +      T+ A  N   +         P+ + + +  TV
Sbjct: 3145 QERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTV 3204

Query: 289  WEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTA 348
               +  +    I+G P+P+++WYK +  ++      K++ + +   +TL +     ED A
Sbjct: 3205 QSGKPARFCAVISGRPQPKISWYKEEQLLST-GFKCKFLHDGQ--EYTLLLIEAFPEDAA 3261

Query: 349  QYRASAMNVKG--ELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
             Y   A N  G    SA  SV V        E   +  A   PL   VT  G  +RF+  
Sbjct: 3262 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQ-- 3319

Query: 407  FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                               CRV  T        ++ WY     + PS++ +     +   
Sbjct: 3320 -------------------CRVSGT------DLKVSWYSKDKKIKPSRFFRMTQFEDTYQ 3354

Query: 467  LTFSHLNKEDEGLYT 481
            L  +    EDEG YT
Sbjct: 3355 LEIAEAYPEDEGTYT 3369



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 83/367 (22%), Positives = 145/367 (39%), Gaps = 60/367 (16%)

Query: 1181 SPRLEVESKGNKTKMTFKDLGMDDLG--IYSCDVTDTDGIASSYLIDEEELKRLLALSHE 1238
            SP  E++++G K  +T   + +D  G  +Y      T  I +   + E EL         
Sbjct: 4942 SPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILT---VKEIELDF------- 4991

Query: 1239 HKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNT 1298
                 VP+K    V + E+ Q RF      L+  A V +      I    K+ +  D   
Sbjct: 4992 ----AVPLKD---VTVPERRQARFECV---LTREANVIWSKGPDIIKSSDKFDIIADGKK 5041

Query: 1299 GIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGP 1358
             I+   +   Q +DEG YT +++ GK T  S  + V  +  K     E Q  +       
Sbjct: 5042 HIL--VINDSQFDDEGVYTAEVE-GKKT--SARLFVTGIRLKFMSPLEDQTVK------- 5089

Query: 1359 HFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEF 1418
                       GE    + C++++ K   H+VW+K++ ++             T+LI+  
Sbjct: 5090 ----------EGETATFV-CELSHEKM--HVVWFKNDAKLHTSR---------TVLISSE 5127

Query: 1419 SKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY 1478
             K      + +  DD  + K+++K +    +  ++E      +   D K     + I L 
Sbjct: 5128 GKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHD-KTAVEKDEITLK 5186

Query: 1479 SFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKT 1538
              V+   +D+ V W  +G  I  S +      G +  L+I +    DKG+YV +    KT
Sbjct: 5187 CEVS---KDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKT 5243

Query: 1539 GHQKTVD 1545
                TV+
Sbjct: 5244 KANVTVE 5250



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEA-GRTAYFTINGV 1636
             L  V+T++ G  + L   V G P PEV+W K++ A        +K +    ++ F++   
Sbjct: 11710 LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKA 11769

Query: 1637  STADSGKYGLVVKNKYGSETSDFTVSV 1663
               +D GKY +   N  GS  +  TV+V
Sbjct: 11770 KRSDGGKYVVTATNTAGSFVAYATVNV 11796



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 5/116 (4%)

Query: 1552  DEAYAEFQRLKQAAIAEKNR----ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWL 1607
             D  Y+E +    + I ++ +    A + G    ++T + G    +   + G P P+V+W 
Sbjct: 22126 DAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWK 22185

Query: 1608  KNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               E  L   D  ++     RT   T+      DSG+Y L ++N  G +T   TV V
Sbjct: 22186 LEEMRLKETDRVSITTTKDRTT-LTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22240



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G+   L  +V G P P + WL+ +K +     C +K      A   +      
Sbjct: 17136 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIRI 17194

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             D G+Y L   N  GS++    V V
Sbjct: 17195 DGGQYILRASNVAGSKSFPVNVKV 17218



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 1/94 (1%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P F+ K ++  + E   +++     G P P + W KN   I  H  P K  IE   G   
Sbjct: 1510 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYP-KIRIEGTKGEAA 1568

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            L+I+    +D+A Y A+A+N  G  +    V V+
Sbjct: 1569 LKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 66/302 (21%), Positives = 111/302 (36%), Gaps = 30/302 (9%)

Query: 224  KQATSALQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKP 283
            K+ +S+    E     S ++ + +  E L L   L E+  Y  K + +     P FI + 
Sbjct: 3407 KEFSSSFLSAEEEGLHSAELQLSKINETLEL---LSESPVYPTKFDSEKEGTGPIFIKEV 3463

Query: 284  RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
             +  +   +   L  ++ G P+P++ W+ N V +   A+  K++ +     H+L I    
Sbjct: 3464 SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSAD-YKFVFDG--DDHSLIILFTK 3520

Query: 344  FEDTAQYRASAMNVKGE--LSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYAS 401
             ED  +Y   A N  G+   SAY  +  K    +  ET      S   L     P     
Sbjct: 3521 LEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP----- 3575

Query: 402  RFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS 461
                HF  +       +G        VV  P      P + W++    L  S +   + +
Sbjct: 3576 ----HFLKELKPIRCAQGLPAIFEYTVVGEP-----APTVTWFKENKQLCTSVYYTIIHN 3626

Query: 462  -GERATLTFSHLNKEDEGLYTIRVR--MGEYYEQYSAYVFVRDAD-----AEIEGAPAAP 513
                 T   +   +ED GLY  +    +GE        V + D D      + +  P AP
Sbjct: 3627 PNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAP 3686

Query: 514  LD 515
             D
Sbjct: 3687 ED 3688



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 43/211 (20%), Positives = 77/211 (36%), Gaps = 25/211 (11%)

Query: 1468 IQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPND-K 1526
            + + +E   +    T      +VNW      +   ++ K         L I++    D +
Sbjct: 4250 VDTVSEEGDIVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQ 4309

Query: 1527 GKYVMELFD--GKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTI 1584
            G+YV E  +  GKT                 A+   +K+AA   K +   L        +
Sbjct: 4310 GEYVCEALNDSGKTATS--------------AKLTVVKRAAPVIKRKIEPL-------EV 4348

Query: 1585 QEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKY 1644
              G     TC +   P     W K  + +   D C+++  +   +   I      D G+Y
Sbjct: 4349 ALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR-SSKYISSLEILRTQVVDCGEY 4407

Query: 1645 GLVVKNKYGSETSDFTVSVFIPEEEARMAAL 1675
                 N+YGS +   T++V +P  E ++  L
Sbjct: 4408 TCKASNEYGSVSCTATLTVTVPGGEKKVRKL 4438



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 72/365 (19%), Positives = 133/365 (36%), Gaps = 62/365 (16%)

Query: 124  LSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKE----AAAYIAQRNLLASEEGIT 179
            L G++ E  PSD +VP   G+  H   + D + E   E    A  +    NL   E  + 
Sbjct: 5733 LKGKKLE--PSDKVVPRSEGKV-HTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVE 5789

Query: 180  TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
             +K           +  T  + +TA  +   SR++   +      +   + + E  ++ +
Sbjct: 5790 FTKPL---------EDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGR 5840

Query: 240  SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
             RK+VI +      ++    + + +    N + +    EF+       V EKE  +  C 
Sbjct: 5841 VRKLVIHDCTPE-DIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECE 5899

Query: 300  IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
            ++     +V W+K+   I       KY I S+  +  L IN C  +D A+Y       + 
Sbjct: 5900 LSR-ENAKVKWFKDGAEIK---KGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTAR- 5954

Query: 360  ELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREG 419
              S   +V+        +E  F    + + +S                          E 
Sbjct: 5955 -TSGMLTVLE-------EEAVFTKNLANIEVS--------------------------ET 5980

Query: 420  ETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 479
            +T+ L C      E+     E+ WY+    +  +   + L  G +  L   + + ED G 
Sbjct: 5981 DTIKLVC------EVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6034

Query: 480  YTIRV 484
            Y  R+
Sbjct: 6035 YNCRL 6039



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 2/84 (2%)

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
            D++ I EG+ L++       P P VSW K+ K + + D   +K +   +A+  +     A
Sbjct: 7898 DIIVI-EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKND-HISAHLEVPKSVRA 7955

Query: 1640 DSGKYGLVVKNKYGSETSDFTVSV 1663
            D+G Y + ++NK GS T+   V V
Sbjct: 7956 DAGIYTITLENKLGSATASINVKV 7979



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 50/209 (23%), Positives = 82/209 (39%), Gaps = 25/209 (11%)

Query: 286   HTVWEKE-NVKLHCSIAGWPEP-RVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
             H V E+  +VK  C I  + +  +VTWY     +    N  KY I    G+  L +    
Sbjct: 25079 HAVGEEGGHVKYVCKIENYDQSTQVTWYFG---VRQLENSEKYEITYEDGVAILYVKDIT 25135

Query: 344   FEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASR- 402
               D   YR   +N  GE S+YA + VK  +  +D   ++   +   +           R 
Sbjct: 25136 KLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYD---YYCRRTMKKIKRRTDTMRLLERP 25192

Query: 403   --FEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSP----SKWV 456
               F +   +K        GE +  G  + + PE     P + WY++G  + P     K+ 
Sbjct: 25193 PEFTLPLYNK----TAYVGENVRFGVTITVHPE-----PHVTWYKSGQKIKPGDNDKKYT 25243

Query: 457   QTLWSGERATLTFSHLNKEDEGLYTIRVR 485
                  G    LT + +  +D+  YT+  R
Sbjct: 25244 FESDKG-LYQLTINSVTTDDDAEYTVVAR 25271



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G++  +  +++G P P + W+K ++ L++     +K     T+  ++      
Sbjct: 16054 DTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATS-LSVKDAVRV 16112

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             DSG Y L  KN  G  +    V V
Sbjct: 16113 DSGNYILKAKNVAGERSVTVNVKV 16136



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 5/96 (5%)

Query: 290   EKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQ 349
             E ++V     ++G P P + W K+  P+++   P   II      + L I     EDT  
Sbjct: 25311 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSL--GPNIEIIHEGLDYYALHIRDTLPEDTGY 25368

Query: 350   YRASAMNVKGELSAYASVVVKRY---KGEFDETRFH 382
             YR +A N  G  S  A + V+R    K EF     H
Sbjct: 25369 YRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEH 25404



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 1/81 (1%)

Query: 1583  TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
             +IQ G+ L +   V G P P +SW+K+ + L      N++  A  T      G +  D G
Sbjct: 17825 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEG-NKDDFG 17883

Query: 1643  KYGLVVKNKYGSETSDFTVSV 1663
             KY +   N  G+ T + +V V
Sbjct: 17884 KYTVTATNSAGTATENLSVIV 17904



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 104/521 (19%), Positives = 194/521 (37%), Gaps = 76/521 (14%)

Query: 1155 SLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTD 1214
            ++ FE         + W K+ V  + + + ++ +K     +  +++   D    + D T 
Sbjct: 2939 TITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGD----AADYTF 2994

Query: 1215 TDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAK 1274
              G A+S      E + +    H        +K    +++LEK +  F  + E    +  
Sbjct: 2995 VAGKATSTATLYVEARHIEFRKH--------IKD---IKVLEKKRAMF--ECEVSEPDIT 3041

Query: 1275 VNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLV 1334
            V ++ +++E+    + K  I +   +  + +   +  D G YT  +  G  +     V  
Sbjct: 3042 VQWMKDDQELQITDRIK--IQKEKYVHRLLIPSTRMSDAGKYTV-VAGGNVSTAKLFVEG 3098

Query: 1335 GDV-FKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYK 1393
             DV  + ++KE +      I KQ                  +++ +V     + H  WYK
Sbjct: 3099 RDVRIRSIKKEVQV-----IEKQ----------------RAVVEFEVNEDDVDAH--WYK 3135

Query: 1394 DEREIS--VDEKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFK 1449
            D  EI+  V E+H +  +  I  + I+E  + DAG Y  +     G+++S + L   A +
Sbjct: 3136 DGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYVNAPE 3191

Query: 1450 --ELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKT 1507
              +++ E+      S    +  +   G              K++W      +    + K 
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRP----------QPKISWYKEEQLLSTGFKCKF 3241

Query: 1508 GVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIA 1567
               G++  L + E  P D   Y  E  +       +  LS +   E  +  Q +     A
Sbjct: 3242 LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV-PEVVSPDQEMPVYPPA 3300

Query: 1568 EKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNL-KFEAG 1626
                  ++  L D VT  EG+     C V G    +VSW   +K +       + +FE  
Sbjct: 3301 ------IITPLQDTVT-SEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED- 3351

Query: 1627 RTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPE 1667
             T    I      D G Y  V  N  G  +S   +S+  PE
Sbjct: 3352 -TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPE 3391



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 40/166 (24%), Positives = 64/166 (38%), Gaps = 21/166 (12%)

Query: 1492 WSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAY 1551
            W  +GS IR S + +    G+   L I +   +D G+Y   L  G      T  L     
Sbjct: 4654 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKL----- 4708

Query: 1552 DEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEK 1611
                          + E+   R +  L + VT+ +G+ L L+C +  +   +V W K+ K
Sbjct: 4709 --------------VVEELPVRFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGK 4752

Query: 1612 ALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETS 1657
             +       +    G     TIN     D+G Y + V+N    E S
Sbjct: 4753 IVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECS 4798



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 61/309 (19%), Positives = 119/309 (38%), Gaps = 50/309 (16%)

Query: 1143 EVVVNVDDDGVISLN---FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKD 1199
            E V +++D  V   +   F C     K+   W ++    ++  + + E  G+  ++  KD
Sbjct: 6327 EFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6386

Query: 1200 LGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVK-SELAVEILEKG 1258
              +DD   Y+C V D    A  ++ +                  +PV+      +ILE  
Sbjct: 6387 CRLDDECEYACGVEDRKSRARLFVEE------------------IPVEIIRPPQDILEAP 6428

Query: 1259 QVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTF 1318
                   AE      +V ++ N   + +G K++M  +    I  + +  ++  D+G Y F
Sbjct: 6429 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGK--IHRLQICDIKPRDQGEYRF 6486

Query: 1319 QLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKC 1378
              +D +A     +     +     K A+   Q+ +   G      + ++           
Sbjct: 6487 IAKDKEARAKLELAAAPKI-----KTAD---QDLVVDVGKPLTMVVPYD----------- 6527

Query: 1379 KVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDK 1438
              A  K E    W+K+   +S  +  D      +  I E  K D G Y+++L++  GK +
Sbjct: 6528 --AYPKAEAE--WFKENEPLST-KTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAE 6582

Query: 1439 S--RLKLVD 1445
                LK++D
Sbjct: 6583 GFINLKVID 6591



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST- 1638
             D V ++ G+A  L  +V G PPP + W K+ K L       +K     T    +N  ST 
Sbjct: 14972 DTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN--LVNKDSTR 15029

Query: 1639  ADSGKYGLVVKNKYGSETSDFTVSV 1663
              DSG Y L   N  G     F V V
Sbjct: 15030 RDSGAYTLTATNPGGFAKHIFNVKV 15054



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 36/155 (23%), Positives = 63/155 (40%), Gaps = 16/155 (10%)

Query: 1510  TGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEK 1569
             +G+  W + N+    DK   +  L +         +   + + E      R ++ A++ K
Sbjct: 23975 SGDSAWKKSNKERIKDKQFTIGGLLEA-------TEYEFRVFAENETGLSRPRRTAMSIK 24027

Query: 1570  NRARVLGGLPDV------VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKF 1623
              +    G  P +      VT + G+A  L+C + G P P++ W +  K L       +  
Sbjct: 24028 TKL-TSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSS 24086

Query: 1624  EAGRTAYFTINGVSTADSGKYGLVVKNKYGS-ETS 1657
             + GRT   T+      D G Y  +  N+ G  ETS
Sbjct: 24087 D-GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 24120



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 112/546 (20%), Positives = 188/546 (34%), Gaps = 108/546 (19%)

Query: 1110 SYVFRVRAINQAGVGKPSDLAGPVVAETRP-----GTKEVVVNVDDDGVISLNFECDKMT 1164
            +Y F + A+  +  G+ S  +  V+   +      GTK V+             EC    
Sbjct: 2378 NYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVL-------------ECKVSV 2424

Query: 1165 PK-SEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
            P  +   W  +    +   R++   KG K ++        D G Y   V     + ++  
Sbjct: 2425 PDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIV---GRVETNCN 2481

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
            +  E++K +  L       T  V  E  VE+   G    W               F +KE
Sbjct: 2482 LSVEKIKIIRGLRDLTCTETQNVVFE--VELSHSGIDVLWN--------------FKDKE 2525

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQK 1343
            I    KYK  I+ +  I ++ +  +  +DEG YTF   +   +   TV   G + K L  
Sbjct: 2526 IKPSSKYK--IEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVA-GGAISKPLTD 2582

Query: 1344 EAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEK 1403
            +   + QE                       + +C+VAN   ++   W +D + + +   
Sbjct: 2583 QTVAESQE----------------------AVFECEVAN--PDSKGEWLRDGKHLPLTNN 2618

Query: 1404 -HDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALS 1462
                 DG    LI   +K D  I E   K    K  ++LK+  EA          KI  +
Sbjct: 2619 IRSESDGHKRRLIIAATKLD-DIGEYTYKVATSKTSAKLKV--EAV---------KIKKT 2666

Query: 1463 ATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPT 1522
              +L +  T + +         V+   V W  NG  +  +++    V G    L+I    
Sbjct: 2667 LKNLTVTETQDAVFTVELTHPNVKG--VQWIKNGVVLESNEKYAISVKGTIYSLRIKNCA 2724

Query: 1523 PNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVV 1582
              D+  Y   L  G+ G    +                ++   I +K         P  V
Sbjct: 2725 IVDESVYGFRL--GRLGASARL---------------HVETVKIIKK---------PKDV 2758

Query: 1583 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
            T  E   +    +V  D  P V W      +   D   L  E  +     +  +S +D+G
Sbjct: 2759 TALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSER-KVHKLMLQNISPSDAG 2816

Query: 1643 KYGLVV 1648
            +Y  VV
Sbjct: 2817 EYTAVV 2822



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  VVTI+    L L   + G P PEV W ++     S D  +++  +  T    +  V+
Sbjct: 15369 LRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGE--SLDKASIESTSSYTLLI-VGNVN 15425

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSGKY L V+N  GS+++   V V
Sbjct: 15426 RFDSGKYILTVENSSGSKSAFVNVRV 15451



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 3/86 (3%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L  ++ I+ G +L L   + G P PEV W K +  +   D   +   +  T+   ++ V+
Sbjct: 16451 LRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIR--DAAIIDVTSSFTS-LVLDNVN 16507

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSGKY L ++N  G++++  TV V
Sbjct: 16508 RYDSGKYTLTLENSSGTKSAFVTVRV 16533



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 7/82 (8%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEK--ALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             ++ G ++ L     G P P   W K +   +L +D H    F        T+   +  D+
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST-----LTVENCNRNDA 21926

Query: 1642  GKYGLVVKNKYGSETSDFTVSV 1663
             GKY L V+N  GS++  FTV V
Sbjct: 21927 GKYTLTVENNSGSKSITFTVKV 21948



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 6/78 (7%)

Query: 1356  QGPHFVEYL-SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVD----EKHDFKDGI 1410
             Q PHF E L +  V  + N  L CKV    K   + WY+  +EI  D       +FK G 
Sbjct: 24429 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI-VKWYRQGKEIIADGLKYRIQEFKGGY 24487

Query: 1411  CTLLITEFSKKDAGIYEV 1428
               L+I   +  DA +Y+V
Sbjct: 24488 HQLIIASVTDDDATVYQV 24505



 Score = 39.7 bits (91), Expect = 0.025
 Identities = 34/135 (25%), Positives = 52/135 (38%), Gaps = 9/135 (6%)

Query: 245   IREKAERLSL-----RKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENV-KLHC 298
             I EK  ++S      +KT E T T   +      + +   I+     T    ++V K   
Sbjct: 26317 IHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAV 26376

Query: 299   SIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVK 358
                G P P   W K+   I      GKY +    G   LEI+  D  D+  Y  +  N  
Sbjct: 26377 KATGEPRPTAIWTKDGKAIT---QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSA 26433

Query: 359   GELSAYASVVVKRYK 373
             G +S+   + +K  K
Sbjct: 26434 GSVSSSCKLTIKAIK 26448



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 36/157 (22%), Positives = 63/157 (40%), Gaps = 10/157 (6%)

Query: 1511 GEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKN 1570
            G   W+   EP    K + V  L +GK    +   L+ Q   +     + ++     E  
Sbjct: 7133 GSDKWVACGEPVAETKME-VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAP 7191

Query: 1571 R----ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG 1626
                  ++L GL    T++ G  + L   V G P P+++W K +  L  D    ++    
Sbjct: 7192 EIFLDVKLLAGL----TVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVP 7246

Query: 1627 RTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
            + +  TI     +D+G Y +   N  G  T+   V+V
Sbjct: 7247 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 11/191 (5%)

Query: 180   TSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKK 239
             TS Q + S Q   S Q +ASKQ  +    ++S  S+ +     S  A S    +E+  + 
Sbjct: 26745 TSLQGSFSSQ---SVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEM 26801

Query: 240   SRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCS 299
             S    +      +S    LE + +   K     +   P+    P   ++ E + + + C+
Sbjct: 26802 SSSSFMG-----ISNMTQLESSTSKMLKAGIRGI--PPKIEALPSDISIDEGKVLTVACA 26854

Query: 300   IAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
               G P P VTW      I+     G++ IE+   + TL I     +D   Y  S  N  G
Sbjct: 26855 FTGEPTPEVTWSCGGRKIH-SQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 26913

Query: 360   ELSAYASVVVK 370
               SA  ++ ++
Sbjct: 26914 SDSATVNIHIR 26924



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 54/228 (23%), Positives = 97/228 (42%), Gaps = 27/228 (11%)

Query: 144  RQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQT-----TASKQSTA 198
            R KH  G T      ++EA   +    L+ S++ +    Q TA  Q      TA     +
Sbjct: 1113 RNKH--GETSASASLLEEADYEL----LMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYS 1166

Query: 199  SKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRKTL 258
              +    K+    R+  A    VV     + ++ +E       + +I+E   R+ ++ TL
Sbjct: 1167 EYEKEYEKEQALIRKKMAKDTVVVR----TYVEDQEFHISSFEERLIKEIEYRI-IKTTL 1221

Query: 259  EET------ETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYK 312
            EE       E     ++E   + +  F  + +++ + E   V  HC ++G+P P++ WYK
Sbjct: 1222 EELLEEDGEEKMAVDISESEAVESG-FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYK 1280

Query: 313  NQVPINVHANPGKYIIE-SRYGMHTLEINGCDFEDTAQYRASAMNVKG 359
            +   I    +  +Y ++  + G  +L I     ED   Y A A N+KG
Sbjct: 1281 DGKRIK---HGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKG 1325



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 63/315 (20%), Positives = 110/315 (34%), Gaps = 43/315 (13%)

Query: 171  LLASEEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSA- 229
            +L  +EGI T+  S        S +      +     +        SR   +S ++ S  
Sbjct: 1308 VLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRS 1367

Query: 230  -LQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTV 288
             ++        +R    R    R+S  + LEET+      ++   L+ P F++KP S   
Sbjct: 1368 PIRMSPARMSPARMSPARMSPARMSPGRRLEETDE-----SQLERLYKPVFVLKPVSFKC 1422

Query: 289  WEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTA 348
             E +  +    + G P P   W+ +   I V+    K +I+   G  +L I      D+ 
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQI-VNDYTHKVVIKED-GTQSLIIVPATPSDSG 1480

Query: 349  QYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFD 408
            ++   A N  G  S    + V+  + +                  V P          F 
Sbjct: 1481 EWTVVAQNRAGRSSISVILTVEAVEHQ------------------VKPM---------FV 1513

Query: 409  DKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGER--AT 466
            +K      +EG  + +  R    P      P+I W +N   + P K+ +    G +  A 
Sbjct: 1514 EKLKNVNIKEGSRLEMKVRATGNP-----NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAA 1568

Query: 467  LTFSHLNKEDEGLYT 481
            L       +D   YT
Sbjct: 1569 LKIDSTVSQDSAWYT 1583



 Score = 38.5 bits (88), Expect = 0.056
 Identities = 76/371 (20%), Positives = 137/371 (36%), Gaps = 83/371 (22%)

Query: 231  QQEETSEKKSRKVVIREKAERLSLRK--TLEETETYHAKLNEDH------LLHAPEFIIK 282
            + ++T E   +  VI +  +R+ + K  TL++  TY   +          ++     ++ 
Sbjct: 6089 RDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVP 6148

Query: 283  PRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGC 342
             +   V E++ V  +C +      +  W++N+  I    +  KYII  +  ++TL I   
Sbjct: 6149 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAI---FDSSKYIILQKDLVYTLRIRDA 6204

Query: 343  DFEDTAQYRASAMNVKGE-LSAYASVVVKR------------YKGEFDETRFHAGASTMP 389
              +D A Y  S  N +GE + + A+++V+                E     F    + + 
Sbjct: 6205 HLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLN 6264

Query: 390  LSFGVTPYGYASRFEIHFD-------DKF-------DVSFGREGETM-------SLGCRV 428
            ++   T  G     E+ FD       DK+       D  F  EGE +       S+   +
Sbjct: 6265 VTLKWTKNGE----EVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELL 6320

Query: 429  VI---TPEIKHFQPE--------------------IQWYRNGVPLSPSKWVQTLWSGERA 465
            +I   T  ++H + +                    ++WYRNG  +   K  +    G   
Sbjct: 6321 IIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIH 6380

Query: 466  TLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLD------VKCL 519
             L       +DE  Y      G    +  A +FV +   EI   P   L+      V   
Sbjct: 6381 RLIIKDCRLDDECEYA----CGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLA 6436

Query: 520  EANKDYIIISW 530
            E NKD + + W
Sbjct: 6437 ELNKDKVEVQW 6447



 Score = 38.5 bits (88), Expect = 0.056
 Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 5/105 (4%)

Query: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKAL--ASDDHCNLKFEAGRTAYFTINGVS 1637
            D + ++ G+ +++  +V G P P++ W KNE  +   +D     K E  R+   T   + 
Sbjct: 8909 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 8968

Query: 1638 TA---DSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLK 1679
             A   D G Y +   N+ GS   +  V V+      R  A+  +K
Sbjct: 8969 KAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIK 9013



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 27/122 (22%), Positives = 55/122 (45%), Gaps = 7/122 (5%)

Query: 1532 ELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALN 1591
            +L +G+ G Q+  +L   A++ A       ++    EK +  ++   P+ V + EG+   
Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQK----EKQKPDIVL-YPEPVRVLEGETAR 1813

Query: 1592 LTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNK 1651
              C V G P P+V+W  N + +       ++++     Y  I    + D+G+  +  +N 
Sbjct: 1814 FRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG--IHYLDIVDCKSYDTGEVKVTAENP 1871

Query: 1652 YG 1653
             G
Sbjct: 1872 EG 1873



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 36/174 (20%), Positives = 69/174 (39%), Gaps = 20/174 (11%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            F C+    K    W K+      S  + + S+G   K+  K++ +DD+      V +   
Sbjct: 5096 FVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSS 5155

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNY 1277
             A   +++ +             + TV +  + AV   EK ++    +  K   +  V +
Sbjct: 5156 TAQLKVLEAD------------PYFTVKLHDKTAV---EKDEITLKCEVSK---DVPVKW 5197

Query: 1278 IFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTV 1331
              + +EI   PKY +  D    I++  ++K   +D+G Y       K   + TV
Sbjct: 5198 FKDGEEIVPSPKYSIKADGLRRILK--IKKADLKDKGEYVCDCGTDKTKANVTV 5249



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 1/83 (1%)

Query: 1581  VVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTAD 1640
             +V  + G  + +   V G P P V+W K ++ L      N +  A  T    IN    +D
Sbjct: 14577 LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST-ILNINECVRSD 14635

Query: 1641  SGKYGLVVKNKYGSETSDFTVSV 1663
             SG Y L  +N  G      T+ V
Sbjct: 14636 SGPYPLTARNIVGEVGDVITIQV 14658



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 18/77 (23%), Positives = 36/77 (46%)

Query: 1587  GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
             G+ +++     G P P ++W K +  + ++ H  +      T+    NGV   D+G Y +
Sbjct: 24545 GEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVV 24604

Query: 1647  VVKNKYGSETSDFTVSV 1663
               KN++G +     + V
Sbjct: 24605 CAKNRFGIDQKTVELDV 24621



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 21/84 (25%), Positives = 33/84 (39%), Gaps = 3/84 (3%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + +  G  + +   V G PPP V+W  NE+ L  +           ++   I     +
Sbjct: 10035 DRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIE---TTAISSSMVIKNCQRS 10091

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
               G Y L+ KN+ G       V V
Sbjct: 10092 HQGVYSLLAKNEAGERKKTIIVDV 10115



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             +  ++T++ G  + L   V+G P P VSW K+   L   +   +  +        +  V+
Sbjct: 12804 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR-NLCTLELFSVN 12862

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               DSG Y +  +N  GS+++   + V
Sbjct: 12863 RKDSGDYTITAENSSGSKSATIKLKV 12888



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 1583  TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
             ++Q G+ L +   + G P P ++W K+   L      N+      T   +I      D G
Sbjct: 16743 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT-LSIKETHKDDGG 16801

Query: 1643  KYGLVVKNKYGSETSDFTV 1661
             +YG+ V N  G +T+   +
Sbjct: 16802 QYGITVANVVGQKTASIEI 16820



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             + +  G+ + L   + G PPP  SW      L   +   ++    + A  TI   +  D+
Sbjct: 23251 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHT-KVAKLTIRETTIRDT 23309

Query: 1642  GKYGLVVKNKYGSETSDFTVSVFI 1665
             G+Y L +KN  G  T+  T+ V I
Sbjct: 23310 GEYTLELKNVTG--TTSETIKVII 23331



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 8/93 (8%)

Query: 1578 LPDVVTIQEGKALNLTCNVWGDPPPEVSWLK-------NEKALASDDHCNLKFEAGRTAY 1630
            L + + ++EG  +N+   + G P P ++W K       N++ +  D H N K     T  
Sbjct: 9625 LKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KLVVDDTCT 9683

Query: 1631 FTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
              I     +D+G Y +   N  G+ + +  ++V
Sbjct: 9684 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9716



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 19/86 (22%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKN-----EKA----LASDDHCNLKFEAGRTAY 1630
             DV+ ++ G+ L +  ++ G P P +SW K+     E+A    +++D+H  L         
Sbjct: 19300 DVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLL--------- 19350

Query: 1631  FTINGVSTADSGKYGLVVKNKYGSET 1656
              T+      D+G+Y L +KN  G+ +
Sbjct: 19351 -TVKDCIRRDTGQYVLTLKNVAGTRS 19375



 Score = 36.6 bits (83), Expect = 0.21
 Identities = 99/530 (18%), Positives = 188/530 (35%), Gaps = 110/530 (20%)

Query: 1142 KEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLG 1201
            K++++   +    S  FEC      +  +W KD  +  +SP+    + G   K+   D+ 
Sbjct: 4625 KDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQ 4684

Query: 1202 MDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVP-VKSELAVEILEKGQV 1260
            + D G Y+C                     +L L ++ K  T   V  EL V  ++  + 
Sbjct: 4685 LSDAGEYTC---------------------VLRLGNKEKTSTAKLVVEELPVRFVKTLEE 4723

Query: 1261 RFW-MQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGII--------EMFMEKLQDE 1311
                ++ + L  + ++N    E+++      K+ +++   I+         + +    D 
Sbjct: 4724 EVTVVKGQPLYLSCELN---KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDT 4780

Query: 1312 DEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGE 1371
            D GTYT  +++      S+ V V +V +           +W+ K            V  +
Sbjct: 4781 DAGTYTVTVENANNLECSSCVKVVEVIR-----------DWLVK------PIRDQHVKPK 4823

Query: 1372 CNVLLKCKVANIKKETHIVWYKDEREISV---DEKHDFKDG-ICTLLITEFSKKDAGIYE 1427
               +  C +A  K   +I W+K   EI     D+    +DG    L I     +D   Y 
Sbjct: 4824 GTAIFACDIA--KDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYA 4881

Query: 1428 VILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY-----SFVT 1482
            V ++  R                       K+ L   ++++    E + +Y     SF  
Sbjct: 4882 VEIEGKR--------------------YPAKLTLGEREVELLKPIEDVTIYEKESASFDA 4921

Query: 1483 YYVE-DLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQ 1541
               E D+   W   G  +R S   +    G + +L +++   +  G+ + +  +  T   
Sbjct: 4922 EISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAIT--- 4978

Query: 1542 KTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPP 1601
             T  L+ +  +  +A    LK   + E+ +AR      + V  +E               
Sbjct: 4979 -TAILTVKEIELDFA--VPLKDVTVPERRQARF-----ECVLTREA-------------- 5016

Query: 1602 PEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNK 1651
              V W K    + S D  ++    G+     IN     D G Y   V+ K
Sbjct: 5017 -NVIWSKGPDIIKSSDKFDI-IADGKKHILVINDSQFDDEGVYTAEVEGK 5064



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 293   NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352
             ++++   I G P P VTW K+ + +   AN     IE+      L I  C+  DT ++  
Sbjct: 14296 SIRIFVPIKGRPAPEVTWTKDNINLKNRAN-----IENTESFTLLIIPECNRYDTGKFVM 14350

Query: 353   SAMNVKGELSAYASVVV 369
             +  N  G+ S + +V V
Sbjct: 14351 TIENPAGKKSGFVNVRV 14367



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKAL-ASDDHCNLKFEAGRTAYFTINGVST 1638
             DV+ +  G+   L  ++ G P P+V W K+ K L  +     +K    +T     + + T
Sbjct: 18218 DVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRT 18277

Query: 1639  ADSGKYGLVVKNKYGSETSDFTVSV 1663
              D G+Y L + N  G+++   TV V
Sbjct: 18278 -DGGQYILKLSNVGGTKSIPITVKV 18301



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 277 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
           P F+ + +S TV +   V+L   + G P P V +Y++   I    +   + I     +++
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD---FQISQEGDLYS 160

Query: 337 LEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
           L I     ED+  Y  +A N  G  ++ A ++V+
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 38/153 (24%), Positives = 61/153 (39%), Gaps = 11/153 (7%)

Query: 221  VVSKQATSALQQEETSEKKSRKVVIREKA-ERLSLRKTLEETETYHAKLNEDHLLHAPEF 279
            V   +  +  + E T  ++ +    R KA  R    K    TE   A   ++    APE 
Sbjct: 7138 VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQE----APEI 7193

Query: 280  IIKPR---SHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
             +  +     TV     ++L  ++ G PEP++TW K  +   +     +  IE+     T
Sbjct: 7194 FLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM---ILKQDKRITIENVPKKST 7250

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
            + I      DT  Y   A+NV G  +A   V V
Sbjct: 7251 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             +VV  + G ++ L   + G P P + W K++K L ++    ++      A   I      
Sbjct: 20383 EVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRL 20441

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
             +SG Y L ++N  GS ++   V +
Sbjct: 20442 NSGCYELKLRNAMGSASATIRVQI 20465



 Score = 35.4 bits (80), Expect = 0.47
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 1/84 (1%)

Query: 1580  DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
             D + I+ G++L +   V G P P V+W K+   +    +  +    G T+ F +   +  
Sbjct: 21469 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF-VRDATRD 21527

Query: 1640  DSGKYGLVVKNKYGSETSDFTVSV 1663
               G Y +  KN  GS  ++  V V
Sbjct: 21528 HRGVYTVEAKNASGSAKAEIKVKV 21551



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 2/64 (3%)

Query: 439 PEIQWYRNGVPLSPS--KWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAY 496
           PE+ W+R+G  +S S    VQ  +S  RA LT   + K + G Y+++   G      +A 
Sbjct: 35  PEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAE 94

Query: 497 VFVR 500
           + V+
Sbjct: 95  LLVK 98



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 1/75 (1%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
             + ++ G  +     + G P P   W  +   + +D+H  ++ +   ++  TI      D+
Sbjct: 11023 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETD-NFSSVLTIKNCLRRDT 11081

Query: 1642  GKYGLVVKNKYGSET 1656
             G+Y + V N  GS+T
Sbjct: 11082 GEYQITVSNAAGSKT 11096



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 292   ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
             E++++   + G P PRVTW+K+ V I    N     I    G  +L +     +    Y 
Sbjct: 21477 ESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDVLGSTSLFVRDATRDHRGVYT 21533

Query: 352   ASAMNVKGELSAYASVVVKRYKGE 375
               A N  G   A   V V+   G+
Sbjct: 21534 VEAKNASGSAKAEIKVKVQDTPGK 21557



 Score = 34.7 bits (78), Expect = 0.80
 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 1/86 (1%)

Query: 1578  LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
             L   + ++ G  + L   V G PPP+++W K    L      ++K       +     V+
Sbjct: 13202 LRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK-STDFDTFLRCENVN 13260

Query: 1638  TADSGKYGLVVKNKYGSETSDFTVSV 1663
               D+GKY L ++N  G +     V V
Sbjct: 13261 KYDAGKYILTLENSCGKKEYTIVVKV 13286



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 41/195 (21%), Positives = 77/195 (39%), Gaps = 19/195 (9%)

Query: 1389 IVWYKDEREISVDE----KHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLV 1444
            + W++D + IS       +  F DG   L I   +K ++G Y +   +  G+  S  +L+
Sbjct: 37   VSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELL 96

Query: 1445 ---DEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRY 1501
               + A    +  +        + +++Q    GI     V +Y          +G+ I+ 
Sbjct: 97   VKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPT-PVVKFY---------RDGAEIQS 146

Query: 1502 SDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR- 1560
            S   +    G+   L I E  P D G Y +   +       T +L  Q  +E  A+  + 
Sbjct: 147  SLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKT 206

Query: 1561 -LKQAAIAEKNRARV 1574
             +  A I+E  + R+
Sbjct: 207  IVSTAQISESRQTRI 221



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 7/94 (7%)

Query: 1577 GLPDVVTIQEGKALNLTCNVWGDPPPEVSWL---KNEKALASDDHC---NLKFE-AGRTA 1629
            G  D +  + G  + +   + G P P+ SW    K +KA+    H    + + E A  ++
Sbjct: 9318 GAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSS 9377

Query: 1630 YFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
               I     + +GKY +  KNK G +T++  V V
Sbjct: 9378 VIIIPECKRSHTGKYSITAKNKAGQKTANCRVKV 9411



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 5/83 (6%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG-RTAYFTINGVSTAD 1640
             + ++ G +  +     G P PE++W + E          ++ E G      +I+     D
Sbjct: 17537 IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSIDNCDRND 17592

Query: 1641  SGKYGLVVKNKYGSETSDFTVSV 1663
             +GKY L ++N  GS+++  TV V
Sbjct: 17593 AGKYILKLENSSGSKSAFVTVKV 17615



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 10/87 (11%)

Query: 1582 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD----DHCNLKFEAGRTAYFTINGVS 1637
            + I  GK L +   V G P P   W K E  L  D    D+   K E        I    
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSE------LIIKDAL 8670

Query: 1638 TADSGKYGLVVKNKYGSETSDFTVSVF 1664
              D G+Y +   N  GS+ +   V VF
Sbjct: 8671 RKDHGRYVITATNSCGSKFAAARVEVF 8697



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 4/109 (3%)

Query: 1358 PHFVEYL-SWEVTGECNVLLKCKVANIKKETHIVWYKDEREI--SVDEKHDFKDGICTLL 1414
            P+FV+ L S  V     V L+ +V  I     + +Y+D  EI  S+D +   +  + +LL
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV-VKFYRDGAEIQSSLDFQISQEGDLYSLL 162

Query: 1415 ITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSA 1463
            I E   +D+G Y V   +  G+  S  +L+ +  +E+  +  K I  +A
Sbjct: 163  IAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTA 211



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 5/67 (7%)

Query: 418  EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDE 477
            EG    L C+V + P++      ++WY N   + P   VQ +  G +  L  +  +  DE
Sbjct: 2412 EGTKAVLECKVSV-PDVT----SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDE 2466

Query: 478  GLYTIRV 484
            G Y + V
Sbjct: 2467 GPYKLIV 2473



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
             I+ G  L L+  + G P P+V+W K ++   +    ++     +     I   +  D G 
Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK---LEIRNAAHEDGGI 10789

Query: 1644  YGLVVKNKYGSETSDFTVSV 1663
             Y L V+N  GS+T    V V
Sbjct: 10790 YSLTVENPAGSKTVSVKVLV 10809



 Score = 33.1 bits (74), Expect = 2.3
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 13/87 (14%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG--RTAYFT---INGV 1636
             + ++ G ++ +   + G P PEV+W K        D+ NLK  A    T  FT   I   
Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTK--------DNINLKNRANIENTESFTLLIIPEC 14340

Query: 1637  STADSGKYGLVVKNKYGSETSDFTVSV 1663
             +  D+GK+ + ++N  G ++    V V
Sbjct: 14341 NRYDTGKFVMTIENPAGKKSGFVNVRV 14367



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 38/176 (21%), Positives = 75/176 (42%), Gaps = 16/176 (9%)

Query: 1165 PKSEFSWSKD--YVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSY 1222
            P  E SW +D   +ST   P +++     + K+T   +   + G YS   T+  G A+S 
Sbjct: 33   PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATS- 91

Query: 1223 LIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEK 1282
                 EL     L      P   V+   ++ + +  QVR  ++   +     V +  +  
Sbjct: 92   ---TAEL-----LVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIP-TPVVKFYRDGA 142

Query: 1283 EIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQD--GKATNHSTVVLVGD 1336
            EI     ++  I +   +  + + +   ED GTY+    +  G+AT+ + +++ G+
Sbjct: 143  EIQSSLDFQ--ISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 43/204 (21%), Positives = 67/204 (32%), Gaps = 47/204 (23%)

Query: 278  EFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTL 337
            + I KP+  T  E   V    S++    P V W+   V I       K+ + S   +H L
Sbjct: 2750 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPS---DKHRLVSERKVHKL 2805

Query: 338  EINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPY 397
             +      D  +Y A    V G+L   A + V+                           
Sbjct: 2806 MLQNISPSDAGEYTA----VVGQLECKAKLFVET-------------------------- 2835

Query: 398  GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQ 457
                   +H           E +T S  C      E+ HF     W +NGV +  S+  +
Sbjct: 2836 -------LHITKTMKNIEVPETKTASFEC------EVSHFNVPSMWLKNGVEIEMSEKFK 2882

Query: 458  TLWSGERATLTFSHLNKEDEGLYT 481
             +  G+   L   + + ED   YT
Sbjct: 2883 IVVQGKLHQLIIMNTSTEDSAEYT 2906



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)

Query: 1584  IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
             ++ G +  +T    G P P V W K +  L +  + +      RT+  TI   +  DSGK
Sbjct: 19701 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDT--TDSRTS-LTIENANRNDSGK 19757

Query: 1644  YGLVVKNKYGSETSDFTVSV 1663
             Y L ++N   + +    V V
Sbjct: 19758 YTLTIQNVLSAASLTLVVKV 19777



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 5/45 (11%)

Query: 418  EGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSG 462
            EGET    CRV   P     QP++ WY NG  +  SK  +  + G
Sbjct: 1808 EGETARFRCRVTGYP-----QPKVNWYLNGQLIRKSKRFRVRYDG 1847



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 17/89 (19%)

Query: 1582  VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALA-------SDDHCNLKFEAGRTAYFTIN 1634
             + +++G  + LT  + G P P   W K  + ++       S+ H  L           I 
Sbjct: 23649 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTEL----------VIK 23698

Query: 1635  GVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
                  DSG Y LV++NK G +     V V
Sbjct: 23699 EADRGDSGTYDLVLENKCGKKAVYIKVRV 23727



 Score = 31.6 bits (70), Expect = 6.8
 Identities = 44/203 (21%), Positives = 71/203 (34%), Gaps = 46/203 (22%)

Query: 278  EFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTL 337
            +F+      TV E E     C ++   +  V W+KN   ++        +I S    H L
Sbjct: 5078 KFMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRT---VLISSEGKTHKL 5133

Query: 338  EINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPY 397
            E+     +D +Q +A       ELS+ A + V                          PY
Sbjct: 5134 EMKEVTLDDISQIKAQVK----ELSSTAQLKVLE----------------------ADPY 5167

Query: 398  GYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQ 457
                 F +   DK  V    E + ++L C V     +K       W+++G  + PS    
Sbjct: 5168 -----FTVKLHDKTAV----EKDEITLKCEVSKDVPVK-------WFKDGEEIVPSPKYS 5211

Query: 458  TLWSGERATLTFSHLNKEDEGLY 480
                G R  L     + +D+G Y
Sbjct: 5212 IKADGLRRILKIKKADLKDKGEY 5234



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 8/88 (9%)

Query: 1598 GDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTIN-GVS-TADSGKYGLVVKNKYGSE 1655
            GDP   V WL + K L + +   +  E G   Y +++ GV+ + DSG       NKYG  
Sbjct: 1684 GDPTMVVEWLHDGKPLEAANRLRMINEFG---YCSLDYGVAYSRDSGIITCRATNKYG-- 1738

Query: 1656 TSDFTVSVFIPEEEARMAALESLKGGKK 1683
             +D T +  I ++E  +     L  G+K
Sbjct: 1739 -TDHTSATLIVKDEKSLVEESQLPEGRK 1765



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 6/60 (10%)

Query: 419  GETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEG 478
            GET +  C      E+ +    ++WY  G  L PS  V     G+  TLT   +  ED G
Sbjct: 5713 GETATFDC------ELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAG 5766



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 1598 GDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETS 1657
            G P P  +W   +K L + D   +K      A   I+    +D G Y L ++N+  + + 
Sbjct: 6923 GYPRPTATWCFGDKVLETGDRVKMK-TLSAYAELVISPSERSDKGIYTLKLENRVKTISG 6981

Query: 1658 DFTVSVFIPEEEARMAALESLKGGKKAK 1685
            +  V+V      AR +A + LK G   K
Sbjct: 6982 EIDVNVI-----ARPSAPKELKFGDITK 7004



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 7/91 (7%)

Query: 1592  LTCNVWGDPPPEVSWLKNEKALASDDHCNLKFE----AGRTAYFTINGVSTADSGKYGLV 1647
             L C V G P P V W +  K + +D    LK+      G      I  V+  D+  Y + 
Sbjct: 24450 LVCKVTGHPKPIVKWYRQGKEIIAD---GLKYRIQEFKGGYHQLIIASVTDDDATVYQVR 24506

Query: 1648  VKNKYGSETSDFTVSVFIPEEEARMAALESL 1678
               N+ GS +   ++ V +P +      LE +
Sbjct: 24507 ATNQGGSVSGTASLEVEVPAKIHLPKTLEGM 24537


>gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens]
          Length = 1326

 Score =  170 bits (431), Expect = 9e-42
 Identities = 146/599 (24%), Positives = 254/599 (42%), Gaps = 70/599 (11%)

Query: 439  PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
            P++ WY++G+ ++  + V      ++A LT S+  +ED GL  ++++        + ++ 
Sbjct: 637  PKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLS 696

Query: 499  VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
            V D     +G       V+ LE +   + + WK P  +GG P+  + +++  VG  SW +
Sbjct: 697  VLDRPKPPQGR------VEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK 750

Query: 559  CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
              +   K   F    + EG++Y FR+ AVN  G+  P    E V A +P E     S+P 
Sbjct: 751  IGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQ 809

Query: 619  APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
                                       VT+ T+  V ++W  P Q G   ++ Y VE+ +
Sbjct: 810  ---------------------------VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRK 842

Query: 678  AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
             G+  W  VN + P++  +  +  L E   Y FRV   N AG G+PS  +   V  D + 
Sbjct: 843  KGSNLWVPVNKD-PIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVK 901

Query: 738  IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFT 797
             P     +  S ++++S+ ++W E  +     GY +E     + +W  C   P+ G+ +T
Sbjct: 902  PPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT 961

Query: 798  CHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSP--DVCPALSDEPGGLT 855
              GL+  Q Y FR+RAVN AG+ E  +  + +    A+    +P  D+   L        
Sbjct: 962  VGGLIERQKYFFRIRAVNEAGVGEPVELDKGVR---AMPPPAAPKFDLSARLKSHMVVRA 1018

Query: 856  ASRGRVHEA---SPP---TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSET------V 903
             +   +H A   SPP    +QKD  + +K  +    S + +      +K S++      +
Sbjct: 1019 GTALCIHAAFSGSPPPDVIWQKDG-VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILL 1077

Query: 904  QEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGA 963
            Q E           G+++ D   +  D   P PP ++   E   +++ L W     +   
Sbjct: 1078 QNEF----------GEARYDIHVRVADF--PRPPTNLRLFEEVPNTVTLTWNHSPDVQED 1125

Query: 964  EITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
                Y +  R   D     W  A  +  S + Y ++ L     Y F+V A N  G   P
Sbjct: 1126 GEAHYIIMKR---DASTATWYTAAERVFSNK-YTVTGLLPGRKYYFRVVARNEIGDSEP 1180



 Score =  115 bits (289), Expect = 3e-25
 Identities = 134/579 (23%), Positives = 230/579 (39%), Gaps = 72/579 (12%)

Query: 915  APQGKSKSDPLKKKTDRA-----PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYY 969
            A   +  SDPL+ +   A     PP         +  ++++ + W  P + GGA + GY 
Sbjct: 778  AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYI 837

Query: 970  VNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECF 1029
            V  R+    +   W   N   +      +  L E+  Y+F+V A+N AG G PS  S   
Sbjct: 838  VERRKKGSNL---WVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSV 894

Query: 1030 KCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRG 1089
              ++  +  PG    L  S+    S+ L W+ P      P +GY ++++    KE  W  
Sbjct: 895  VAKD-PVKPPGLVQDLHVSDSSNSSISLAWREPAEGD--PPSGYILEMRAEDTKE--WSK 949

Query: 1090 LNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVN-- 1147
              +  I      V GL E   Y FR+RA+N+AGVG+P +L   V A   P   +  ++  
Sbjct: 950  CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSAR 1009

Query: 1148 -----VDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGM 1202
                 V   G           +P  +  W KD V T+   R  +    N ++        
Sbjct: 1010 LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKG--RETITKSKNHSQFLINSTKR 1067

Query: 1203 DDLGIYSCDVTDTDGIA--------------SSYLIDEEELKRLLALSHEHKFPTVPVKS 1248
             D G+Y   + +  G A               + L   EE+   + L+  H  P V    
Sbjct: 1068 SDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHS-PDVQEDG 1126

Query: 1249 ELAVEILEK--GQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFME 1306
            E    I+++      ++  AE++  N      +    +  G KY   +     I +   E
Sbjct: 1127 EAHYIIMKRDASTATWYTAAERVFSNK-----YTVTGLLPGRKYYFRVVARNEIGD--SE 1179

Query: 1307 KLQDEDEGTYT-FQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLS 1365
             L   D       Q+QD  A                 K   +++++W  +  P FV  L 
Sbjct: 1180 PLDSRDTWLINKDQIQDLSA-----------------KLKPYEKKDW--RHAPRFVTPLK 1220

Query: 1366 -WEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEK--HDFKDGICTLLITEFSKKD 1422
               V    +  + C      + T +  YK +  I+ + K  ++   G+CTL+I   + KD
Sbjct: 1221 PHTVLRGQDCTMTCAFLGNPRPT-VTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKD 1279

Query: 1423 AGIYEVILKDDRGKDKS--RLKLVDEAFKELMMEVCKKI 1459
            +G Y V+++++ GKD+S   L + D+  K ++  + + +
Sbjct: 1280 SGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESL 1318



 Score = 88.6 bits (218), Expect = 5e-17
 Identities = 61/204 (29%), Positives = 94/204 (46%), Gaps = 7/204 (3%)

Query: 933  PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVS 992
            P  P   +  LE     + + WK P   GG  +T + V  R V      K  E + K  +
Sbjct: 701  PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760

Query: 993  EEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRK 1052
               +  + ++E   YQF++ A+N  G+  P    E F      I  PG     + ++V K
Sbjct: 761  ---FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNP--IEPPGFASQPQVTDVTK 815

Query: 1053 DSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYV 1112
            +++ + W  P   G  PV GY V+ +  K   + W  +N+  I+     V GL E   Y 
Sbjct: 816  EAVTITWNAPTQDGGAPVLGYIVERR--KKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE 873

Query: 1113 FRVRAINQAGVGKPSDLAGPVVAE 1136
            FRV A+N+AG G+PS  +  VVA+
Sbjct: 874  FRVIAVNKAGPGQPSVPSSSVVAK 897



 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 154/805 (19%), Positives = 276/805 (34%), Gaps = 166/805 (20%)

Query: 304  PEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSA 363
            P  ++ W K   P+ +  + GKY ++     + L I+  +  D   Y  S  + +  +SA
Sbjct: 262  PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR--MSA 319

Query: 364  YASVVVK--RYKGEFDETRF-HAGASTMPLSFGVTPYGYASRF---EIHFDDKFDVSFGR 417
              +V+ +  ++ GE    +      +   +        +  +F   E+  DDK++++   
Sbjct: 320  ELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSE 379

Query: 418  EGETMSLGCRVVITPEIKHFQPE------------------------------------- 440
            +G T +L  +     +   F  E                                     
Sbjct: 380  DGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLE 439

Query: 441  ---------IQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYT-IRVRMGEYY 490
                     ++W ++G  L           G+RA L        D G YT + ++ G+  
Sbjct: 440  CELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPT 499

Query: 491  EQYSAYVF--------VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPIL 542
            E YS  +         V+   +++  A  +P ++ C+  N + +   W +   DG     
Sbjct: 500  EYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLK---DG----- 550

Query: 543  GYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPV 602
                           +  D P                 I +  AV+K  + FPS      
Sbjct: 551  --------------KEITDLP--------------GMQIVKQGAVHK--LIFPS------ 574

Query: 603  AALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPG 662
              + P  + +   R           TE E S  I   P  D SV EA  ++ +      G
Sbjct: 575  --MGPEHEGKYTFRAKG--------TESEASVFIADPPTIDPSVLEALAAHAIT--VKVG 622

Query: 663  QRGH----------EGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRV 712
               H            + ++ +  E   E  +RV+ E         + +     S    +
Sbjct: 623  HTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVREDSGLILL 680

Query: 713  RCSNSAGVGEPSEATEVTVVGDKLDIPKAP-GKIIPSRNTDTSVVVSWEESKD--AKELV 769
            +  N  G      +   T+    LD PK P G++     + + V + W+  KD   + + 
Sbjct: 681  KLKNDHG------SATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734

Query: 770  GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAI 829
             + +E    G   W        K + F+ + +  G++Y FR+ AVN+ G+S+  +  E  
Sbjct: 735  QFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF 794

Query: 830  EVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEA-SPPTFQKDALL----------GSK 878
                  G  + P   P  + +P     ++  V    + PT    A +          GS 
Sbjct: 795  -----AGNPIEP---PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSN 846

Query: 879  PNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAP-QGKSKSDPLKKKTDRAPPSPP 937
               P      Q    T    + +T  E       KA P Q    S  +  K    PP   
Sbjct: 847  LWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLV 906

Query: 938  CDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYK 997
             D+   +S   S+ L W++P +  G   +GY +  R        +W +     +S   Y 
Sbjct: 907  QDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRA---EDTKEWSKCTKIPISGTCYT 961

Query: 998  ISNLKENMVYQFQVAAMNMAGLGAP 1022
            +  L E   Y F++ A+N AG+G P
Sbjct: 962  VGGLIERQKYFFRIRAVNEAGVGEP 986



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 100/485 (20%), Positives = 178/485 (36%), Gaps = 74/485 (15%)

Query: 1183 RLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFP 1242
            + +V+  G K  +   ++ M+D GIYS  V D    A   ++DE      L    E K  
Sbjct: 283  KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEP-----LKFLGEMK-- 335

Query: 1243 TVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIE 1302
              PVK      + E+    F ++  K   N    + FN KE+    KY++ +        
Sbjct: 336  --PVK------VTERQTAVFEIRLSKKEPNFV--WKFNGKELKRDDKYEITVS------- 378

Query: 1303 MFMEKLQDEDEGTYTFQLQDGKATNHSTVVL-VGDVFKKLQKEAEFQRQEWIRKQGPHFV 1361
                    ED  T+T +++D + ++        G++ +K Q          I +    FV
Sbjct: 379  --------EDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLT--------IDRIPIKFV 422

Query: 1362 EYL-SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEF 1418
              L +  V       L+C++ +  K+  + W KD + +    K+    +     L+I + 
Sbjct: 423  SNLKNVRVKERSRACLECELTS--KDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDA 480

Query: 1419 SKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY 1478
               D G Y V+   D            E +   ++ V +++A   + +     A G    
Sbjct: 481  QLSDGGEYTVVAMQDGDPT--------EYYSTAIVTVEERLATVKSGMSDVHAATGSPAE 532

Query: 1479 SFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKT 1538
              V    E ++  W  +G  I     ++    G    L      P  +GKY      G  
Sbjct: 533  LCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA-KGTE 591

Query: 1539 GHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWG 1598
                         D +  E       A+A              +T++ G   ++     G
Sbjct: 592  SEASVFIADPPTIDPSVLE-------ALAAH-----------AITVKVGHTAHIKVPFRG 633

Query: 1599 DPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSD 1658
             P P+V+W K+   +  ++  +++      A  TI+     DSG   L +KN +GS T+ 
Sbjct: 634  KPLPKVTWYKDGMEVTEEERVSME-RGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692

Query: 1659 FTVSV 1663
              +SV
Sbjct: 693  LHLSV 697



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 44/190 (23%), Positives = 77/190 (40%), Gaps = 21/190 (11%)

Query: 439  PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
            P++ W ++GVP    + +    S   +    +   + D G+Y I ++      +Y  +V 
Sbjct: 1034 PDVIWQKDGVPTKGRETITK--SKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091

Query: 499  VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
            V D        P  P +++  E   + + ++W             Y I K +  T +W  
Sbjct: 1092 VADF-------PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144

Query: 559  CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFP-----------SRVSEPVAALDP 607
              +  V   ++ VTGL+ GR Y FRV A N++G   P            ++ +  A L P
Sbjct: 1145 AAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203

Query: 608  AEKARLKSRP 617
             EK   +  P
Sbjct: 1204 YEKKDWRHAP 1213



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 275  HAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGM 334
            HAP F+   + HTV   ++  + C+  G P P VT YK  V  N+ AN  K+   S  G+
Sbjct: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDV--NITAN-SKFWYNSTSGV 1267

Query: 335  HTLEINGCDFEDTAQYRASAMNVKGE 360
             TL I  C  +D+  Y     N  G+
Sbjct: 1268 CTLVIPTCTLKDSGDYSVLVENELGK 1293



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 32/116 (27%), Positives = 50/116 (43%), Gaps = 4/116 (3%)

Query: 638  PGPPTDLSVTEATRSYVVLSWKPPGQRGHEG-IMYFVEKCEAGTENWQRVNTELPVKSPR 696
            P PPT+L + E   + V L+W        +G   Y + K +A T  W        V S +
Sbjct: 1096 PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAER--VFSNK 1153

Query: 697  FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTD 752
            + +  L  G+ Y FRV   N  G  EP ++ +  ++ +K  I     K+ P    D
Sbjct: 1154 YTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLI-NKDQIQDLSAKLKPYEKKD 1208



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 31/107 (28%), Positives = 58/107 (54%), Gaps = 10/107 (9%)

Query: 1583 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTA---YFTINGVSTA 1639
            T+  G+   +TC   G+P P V+  K +  + +    N KF    T+      I   +  
Sbjct: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA----NSKFWYNSTSGVCTLVIPTCTLK 1278

Query: 1640 DSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAAL-ESLKGGKKAK 1685
            DSG Y ++V+N+ G + S  T++V+  ++++ +A++ ESL+  KK+K
Sbjct: 1279 DSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQ--KKSK 1323



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 62/294 (21%), Positives = 114/294 (38%), Gaps = 46/294 (15%)

Query: 1159 ECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSC----DVTD 1214
            EC+  +      W KD        +  +  +G + ++  +D  + D G Y+     D   
Sbjct: 439  ECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDP 498

Query: 1215 TDGIASSYLIDEEELKRLLA-LSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
            T+  +++ +  EE L  + + +S  H     P  +EL V + ++     W++        
Sbjct: 499  TEYYSTAIVTVEERLATVKSGMSDVHAATGSP--AELCVVLNDEKVEGVWLK-------- 548

Query: 1274 KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1333
                  + KEI + P   M I +   + ++    +  E EG YTF+    K T     V 
Sbjct: 549  ------DGKEITDLP--GMQIVKQGAVHKLIFPSMGPEHEGKYTFR---AKGTESEASVF 597

Query: 1334 VGDVFKKLQKEAEFQRQEWIRKQGPHFVEYL-SWEVTGECNVLLKCKVA-NIKKETHIVW 1391
            + D                     P  +E L +  +T +       KV    K    + W
Sbjct: 598  IADP----------------PTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW 641

Query: 1392 YKDEREISVDEKHDFKDG--ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
            YKD  E++ +E+   + G     L I+   ++D+G+  + LK+D G   + L L
Sbjct: 642  YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHL 695



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 3/82 (3%)

Query: 1582 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
            + ++ G AL +     G PPP+V W K+       +      ++   + F IN    +DS
Sbjct: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT---KSKNHSQFLINSTKRSDS 1070

Query: 1642 GKYGLVVKNKYGSETSDFTVSV 1663
            G Y ++++N++G    D  V V
Sbjct: 1071 GVYRILLQNEFGEARYDIHVRV 1092



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 74/346 (21%), Positives = 138/346 (39%), Gaps = 57/346 (16%)

Query: 1339 KKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREI 1398
            K+++K+ E    E IR   P   +    + T   + +++ K  N+K    ++W K    +
Sbjct: 223  KEMKKKVEV---EAIRILKPLEDKETKVDTTVVFDCIMELKDPNVK----MIWIKGTEPL 275

Query: 1399 SVDE---KHDFKD--GICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1453
             +     K+D K       L+I+  +  DAGIY + + D R    + L ++DE  K L  
Sbjct: 276  RIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR--MSAELTVLDEPLKFLGE 333

Query: 1454 EVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQ 1513
                K+       + Q+    I+L      +V      W  NG  ++  D+ +  V+ + 
Sbjct: 334  MKPVKVT------ERQTAVFEIRLSKKEPNFV------WKFNGKELKRDDKYEITVSEDG 381

Query: 1514 I--WLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR 1571
            +   L+I +   +D G++  E  +     Q T+D     +         LK   + E++R
Sbjct: 382  LTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKF------VSNLKNVRVKERSR 435

Query: 1572 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYF 1631
            A                   L C +       + W K+ + L      ++  E G+ A  
Sbjct: 436  A------------------CLECEL-TSKDVTLRWKKDGQLLMHGTKYSMNHE-GKRAEL 475

Query: 1632 TINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALES 1677
             I     +D G+Y  VV  + G  T  ++ ++   EE  R+A ++S
Sbjct: 476  IIEDAQLSDGGEY-TVVAMQDGDPTEYYSTAIVTVEE--RLATVKS 518



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 36/168 (21%), Positives = 69/168 (41%), Gaps = 9/168 (5%)

Query: 211 SRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNE 270
           SRQ      S+    +T+ +Q    + K   + V+R K+  +    +L  T + +    +
Sbjct: 6   SRQMLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLV-TRSSNIPAGD 64

Query: 271 DHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQ-VPINVHANPGKYIIE 329
                 PEF+ KP+  T  E +       + G  +P ++W +   +PI   A   K   +
Sbjct: 65  S----VPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA---KIFYD 117

Query: 330 SRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFD 377
           S    H L++     +D+  Y+  A N   +     S++V   + + D
Sbjct: 118 SINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMD 165


>gi|148839296 immunoglobulin-like and fibronectin type III domain
            containing 1 [Homo sapiens]
          Length = 868

 Score =  132 bits (331), Expect = 4e-30
 Identities = 137/613 (22%), Positives = 237/613 (38%), Gaps = 62/613 (10%)

Query: 428  VVITPEIKHFQPEIQWYRNGVPL--SPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVR 485
            +V  P   H   +  W ++G  +  S  +  Q         L      ++D G Y++ +R
Sbjct: 184  IVKIPFQSHLPIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLR 243

Query: 486  MGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYF 545
                  Q    + V D        P  P++V+  + ++  + + W+ P  +GG  +  Y 
Sbjct: 244  SEGGSVQAELTLQVIDKP----DPPQGPMEVQ--DCHRAGVCLRWRPPRDNGGRTVECYV 297

Query: 546  IDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAAL 605
            +++ + G  +W +  + P     F    +  GR Y FRVRAV   G G      E + A 
Sbjct: 298  VERRQAGRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAP 357

Query: 606  DPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRG 665
            +   KA     PSAP                        ++  A+   + L+W  P   G
Sbjct: 358  EALPKA-----PSAP------------------------AILSASSQGITLTWTAPRGPG 388

Query: 666  HEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPS 724
               I+ Y +E+ + G+  W  VN + PV   R+ + D+ +G  Y FRV     +G GEP 
Sbjct: 389  SAHILGYLIERRKKGSNTWTAVNDQ-PVPERRWTVADVRQGCQYEFRVTAVAPSGPGEPG 447

Query: 725  EATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSW--EESKDAKELVGYYIEASVAGSGK 782
              ++     D +  P     +  +  ++TS+ +SW   ++++  E  GY +E   + S +
Sbjct: 448  PPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQ 507

Query: 783  WEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPD 842
            W PC+   V  + +T  GL  G+ Y  RV AVN  G S+ S     ++        +   
Sbjct: 508  WLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQ-------AMPVT 560

Query: 843  VCPAL---SDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNL-----GQT 894
            VCP     S     LT   G      P +F+   +      K  LP   +++     G T
Sbjct: 561  VCPKFLVDSSTKDLLTVKVGDTVRV-PVSFEAMPMPEVTWLKDGLPLPKRSVTVTKDGLT 619

Query: 895  EVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGW 954
            ++      + +           QGK  +   + +   A P  P  I   E+   ++   W
Sbjct: 620  QLLIPVAGLSDSGLYTVVLRTLQGKEVAHSFRIRV-AACPQAPGPIHLQENVPGTVTAEW 678

Query: 955  KQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAM 1014
             +P      ++  +Y  +        G W EA    +    + +  +     Y F+V A 
Sbjct: 679  -EPSPDEAQDVPLHYAVFTR--SSAHGPWHEA-ADRIHTNRFTLLGILPGHEYHFRVVAK 734

Query: 1015 NMAGLGAPSAVSE 1027
            N  G   PS  S+
Sbjct: 735  NELGASKPSDTSQ 747



 Score = 97.8 bits (242), Expect = 8e-20
 Identities = 116/536 (21%), Positives = 210/536 (39%), Gaps = 55/536 (10%)

Query: 932  APPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAV 991
            A P  P     L +    + L W  P   G A I GY +  R+        W   N + V
Sbjct: 359  ALPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNT---WTAVNDQPV 415

Query: 992  SEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVR 1051
             E  + ++++++   Y+F+V A+  +G G P   S+     +  +  PG   +L+ ++  
Sbjct: 416  PERRWTVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFARD-PMRPPGLVRNLQVTDRS 474

Query: 1052 KDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSY 1111
              S+ L W  P         GY V+L  + +   QW   +   +       +GL+ G  Y
Sbjct: 475  NTSITLSWAGPDTQEGDEAQGYVVELCSSDSL--QWLPCHVGTVPVTTYTAKGLRPGEGY 532

Query: 1112 VFRVRAINQAGVGKPSDL-----AGPVVAETR----PGTKEVV-VNVDDDGVISLNFECD 1161
              RV A+N+ G  +PS L     A PV    +      TK+++ V V D   + ++FE  
Sbjct: 533  FVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEA- 591

Query: 1162 KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG--IA 1219
               P  E +W KD +      R    +K   T++     G+ D G+Y+  +    G  +A
Sbjct: 592  --MPMPEVTWLKDGLPL--PKRSVTVTKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVA 647

Query: 1220 SSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIF 1279
             S+ I      +     H  +     V +E             W  +   + +  ++Y  
Sbjct: 648  HSFRIRVAACPQAPGPIHLQENVPGTVTAE-------------WEPSPDEAQDVPLHYAV 694

Query: 1280 NEKEIFEGPKY----KMHIDRNT--GII---EMFMEKLQDEDEGTYTFQLQDGKATNHST 1330
              +    GP +    ++H +R T  GI+   E     +   + G         K ++ S 
Sbjct: 695  FTRSSAHGPWHEAADRIHTNRFTLLGILPGHEYHFRVVAKNELGA-------SKPSDTSQ 747

Query: 1331 VVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIV 1390
               +     +   +A   R+  + ++    V   S  +   C   + C V       H+ 
Sbjct: 748  PWCIPRQRDRFTVKAPCYREPDLSQKPRFLVGLRSHLLPQGCECCMSCAVQG-SPRPHVT 806

Query: 1391 WYKDEREISVDEKHDFKD--GICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLV 1444
            W+K++R +  +      D  G+C+L I   S KD+G Y+ + ++  G+  S   L+
Sbjct: 807  WFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENTLGQAVSTATLI 862



 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 64/264 (24%), Positives = 101/264 (38%), Gaps = 29/264 (10%)

Query: 875  LGSKPNKPSLPSSSQ-NLGQTEVSKVSE--TVQEELTPPPQKAAPQGKSKSDPLKKKTDR 931
            LG    +  LPS+ + + GQ  V+  SE  +VQ ELT        Q   K DP       
Sbjct: 218  LGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTL-------QVIDKPDP------- 263

Query: 932  APPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAV 991
              P  P ++   +  R  + L W+ P   GG  +  Y V  R+        W +      
Sbjct: 264  --PQGPMEVQ--DCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRST---WLKVGEAPA 316

Query: 992  SEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVR 1051
                +  ++++    Y F+V A+   G G      E     E     P  P  L  S   
Sbjct: 317  DSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAILSASS-- 374

Query: 1052 KDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSY 1111
               + L W  P   G   + GY ++ +  K   + W  +N+  +      V  +++G  Y
Sbjct: 375  -QGITLTWTAPRGPGSAHILGYLIERR--KKGSNTWTAVNDQPVPERRWTVADVRQGCQY 431

Query: 1112 VFRVRAINQAGVGKPSDLAGPVVA 1135
             FRV A+  +G G+P   +  V A
Sbjct: 432  EFRVTAVAPSGPGEPGPPSDAVFA 455



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 270 EDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIE 329
           E  L   P F++  RSH + +     + C++ G P P VTW+KN    ++  NP  Y  +
Sbjct: 767 EPDLSQKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKND--RSLEGNPAVYSTD 824

Query: 330 SRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVV 369
              G+ +L I     +D+ +Y+A A N  G+  + A+++V
Sbjct: 825 -LLGVCSLTIPSVSPKDSGEYKAVAENTLGQAVSTATLIV 863



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 41/163 (25%), Positives = 65/163 (39%), Gaps = 9/163 (5%)

Query: 439 PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
           PE+ W ++G+PL P + V     G    L        D GLYT+ +R  +  E   ++  
Sbjct: 595 PEVTWLKDGLPL-PKRSVTVTKDG-LTQLLIPVAGLSDSGLYTVVLRTLQGKEVAHSFRI 652

Query: 499 VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
                  +   P AP  +   E     +   W+    +     L Y +         W +
Sbjct: 653 ------RVAACPQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHE 706

Query: 559 CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEP 601
             D  +   RF + G++ G  Y FRV A N++G   PS  S+P
Sbjct: 707 AADR-IHTNRFTLLGILPGHEYHFRVVAKNELGASKPSDTSQP 748



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 1584 IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
            + +G    ++C V G P P V+W KN+++L  +         G     TI  VS  DSG+
Sbjct: 785  LPQGCECCMSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLG-VCSLTIPSVSPKDSGE 843

Query: 1644 YGLVVKNKYGSETSDFTVSVFIP 1666
            Y  V +N  G   S  T+ V  P
Sbjct: 844  YKAVAENTLGQAVSTATLIVIEP 866



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 37/163 (22%), Positives = 62/163 (38%), Gaps = 39/163 (23%)

Query: 1294 IDRNTGIIE-MFMEKLQDEDEGTYTF----QLQDGKATNHSTVVLVGDVFKKLQKEAEFQ 1348
            I +  G++  +F+  +Q    G YTF    Q  +   T   +  +  DV +KL       
Sbjct: 119  IFKQDGLVHSLFITHVQGTQAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKL------- 171

Query: 1349 RQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHI----VWYKDEREI----SV 1400
            R+  + K G                   K  +  I  ++H+     W KD  E+      
Sbjct: 172  REPLVVKAG-------------------KPVIVKIPFQSHLPIQAAWRKDGAEVVGSSDR 212

Query: 1401 DEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
            + + D  DG   L +    +KD G Y V L+ + G  ++ L L
Sbjct: 213  EAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTL 255


>gi|46049110 myosin binding protein C, slow type isoform 4 [Homo
           sapiens]
          Length = 1123

 Score =  117 bits (294), Expect = 7e-26
 Identities = 86/304 (28%), Positives = 133/304 (43%), Gaps = 40/304 (13%)

Query: 439 PEIQWYRNGVPLSP-SKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
           P+  W R    +   S  ++T    + +TL      ++D G+Y I ++     E   A+ 
Sbjct: 555 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN----EAGEAHA 610

Query: 498 FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
            ++    +    P AP      E   D+ I++W+ PA DGGSPILGYFI++ +  +  W 
Sbjct: 611 SIKVKVVDFPDPPVAPT---VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 667

Query: 558 QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRP 617
           + N    K   F    +IEG +Y  R+ AVN +GI  PS  S P   L            
Sbjct: 668 RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPL------------ 715

Query: 618 SAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKC 676
                              V  PPT L+V   T + V + W+PP   G  G+  Y +E C
Sbjct: 716 ------------------AVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757

Query: 677 EAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
             GTE+W   N +L +   +F +  L        RV+  N+AG  EP   ++  +V + +
Sbjct: 758 FEGTEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 816

Query: 737 DIPK 740
           + PK
Sbjct: 817 EPPK 820



 Score =  114 bits (284), Expect = 1e-24
 Identities = 180/759 (23%), Positives = 287/759 (37%), Gaps = 125/759 (16%)

Query: 287  TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
            T +  E V+L C ++   +  V W+KN   I +     +Y I      H L I G    D
Sbjct: 352  TAYCGERVELECEVSE-DDANVKWFKNGEEI-IPGPKSRYRIRVEGKKHILIIEGATKAD 409

Query: 347  TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
             A+Y  S M   G+ SA  SV +K                  PL   +TP          
Sbjct: 410  AAEY--SVMTTGGQSSAKLSVDLK------------------PLKI-LTPL--------- 439

Query: 407  FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                         +T++LG  + +  EI    P  +W +NG+P+  S  ++ +  G    
Sbjct: 440  -----------TDQTVNLGKEICLKCEISENIPG-KWTKNGLPVQESDRLKVVHKGRIHK 487

Query: 467  LTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYI 526
            L  ++   EDEG         +Y     AY     A   +   P   LD   L+A+    
Sbjct: 488  LVIANALTEDEG---------DYVFAPDAYNVTLPAKVHVIDPPKIILDG--LDADNTVT 536

Query: 527  IISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRA 586
            +I+  +  ++   PI G    K       WS+ +      A    +G I   SY      
Sbjct: 537  VIAGNKLRLE--IPISGEPPPKA-----MWSRGDK-----AIMEGSGRIRTESYPDSSTL 584

Query: 587  VNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSV 646
            V    I    R    V  ++   +A       A  + ++ V +        P PP   +V
Sbjct: 585  V----IDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVD-------FPDPPVAPTV 628

Query: 647  TEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEG 705
            TE    + +++W+PP   G   I+ YF+E+ +  +  W R+N +L  K   F    + EG
Sbjct: 629  TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEG 687

Query: 706  KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESK 763
             +Y  R+   N+ G+ +PS  +   V    L +   P  +     TDT+V + W   +  
Sbjct: 688  VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744

Query: 764  DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823
             A  L GY +E    G+  W   N + +  ++FT  GL T      RV+AVNAAG SE  
Sbjct: 745  GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 804

Query: 824  QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPS 883
              S+ I VK  I              EP  +   R           +   L+     KP 
Sbjct: 805  YYSQPILVKEII--------------EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 850

Query: 884  LPSSSQNLGQTEVSKVSETVQEELTPP---PQKAAPQGKSKSDPLKKKTDR--------- 931
             P  +      E+ K    ++   T      +KA      K D L+ K D+         
Sbjct: 851  -PELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYD-LQVKVDKFVETASIDI 908

Query: 932  ---APPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
                 P PP  +   + + +++ L W  P   G A ITGY +   +  D    +W    +
Sbjct: 909  QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTI---QKADKKSMEWFTV-I 964

Query: 989  KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
            +     +  I+ L     Y F+V + NM GL   + +++
Sbjct: 965  EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1003



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 119/536 (22%), Positives = 202/536 (37%), Gaps = 65/536 (12%)

Query: 934  PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
            P PP   T  E   D  ++ W+ P   GG+ I GY++  ++       +W   N     E
Sbjct: 620  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS---RWMRLNFDLCKE 676

Query: 994  EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
              ++   + E + Y+ ++ A+N  G+  PS  S  F      +AV  PP  L    V   
Sbjct: 677  TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTVDSVTDT 732

Query: 1054 SLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVF 1113
            ++ ++W+PP H G   + GY   L+      + W   N+  I      + GL        
Sbjct: 733  TVTMRWRPPDHIGAAGLDGYV--LEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFV 790

Query: 1114 RVRAINQAGVGKPSDLAGPVVAE----------TRPGTKEVVVNVDDDGVISLNFECDKM 1163
            RV+A+N AG  +P   + P++ +           R   +  +  V +   + + F+    
Sbjct: 791  RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ---G 847

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
             P+ E +W KD     D  ++ + +    T +  +       G Y   V   D    +  
Sbjct: 848  KPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQV-KVDKFVETAS 905

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV-NYIFN-- 1280
            ID + + R          P  P    + +E +    V       K  GNA +  Y     
Sbjct: 906  IDIQIIDR----------PGPP--QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 953

Query: 1281 EKEIFEGPKYKMHIDRNTGII-------EMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1333
            +K+  E      H  R +  I       E +     +   G      +D   T  S V+ 
Sbjct: 954  DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL----SEDATMTKESAVIA 1009

Query: 1334 -VGDVFKK-LQKEAEFQRQEWIRKQGPHFVEYL--SWEVTGECNVLLKCKVANIKKETHI 1389
              G ++K  + ++ +F        + P F + L  ++ + G  N  L C V    K   I
Sbjct: 1010 RDGKIYKNPVYEDFDF-------SEAPMFTQPLVNTYAIAG-YNATLNCSVRGNPK-PKI 1060

Query: 1390 VWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
             W K++  I  D ++      G+CTL I + S  D G Y     +D G  +   KL
Sbjct: 1061 TWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1116



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 105/445 (23%), Positives = 169/445 (37%), Gaps = 76/445 (17%)

Query: 1229 LKRLLALSHEHKFPTVPVKS-ELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEG 1287
            LKRL  +  E K      K  + A ++ + G+VRF +  E      +V +  N +EI   
Sbjct: 238  LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 295

Query: 1288 PKYKMHIDRNTGIIE-MFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAE 1346
             KY   I  + G    +F+   Q  D+  Y     D K    ST + V +    + K+ E
Sbjct: 296  TKY---IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC---STELFVREPPIMVTKQLE 349

Query: 1347 FQRQEWIRKQGPHFVEYLSWEVTGECN--VLLKCKVANIKKETHIVWYKDEREISVDEKH 1404
                                + T  C   V L+C+V+  + + ++ W+K+  EI    K 
Sbjct: 350  --------------------DTTAYCGERVELECEVS--EDDANVKWFKNGEEIIPGPKS 387

Query: 1405 DFK---DGICTLLITE-FSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIA 1460
             ++   +G   +LI E  +K DA  Y V+    +   K  + L     K L      KI 
Sbjct: 388  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-----KPL------KIL 436

Query: 1461 LSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINE 1520
               TD  +    E I L   ++   E++   W+ NG  ++ SDR+K    G    L I  
Sbjct: 437  TPLTDQTVNLGKE-ICLKCEIS---ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 492

Query: 1521 PTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGL-- 1578
                D+G YV         +  T+       D                     +L GL  
Sbjct: 493  ALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKI-----------------ILDGLDA 531

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
             + VT+  G  L L   + G+PPP+  W + +KA+              ++   I+    
Sbjct: 532  DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAER 591

Query: 1639 ADSGKYGLVVKNKYGSETSDFTVSV 1663
             DSG Y + +KN+ G   +   V V
Sbjct: 592  DDSGVYHINLKNEAGEAHASIKVKV 616



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 38/169 (22%), Positives = 76/169 (44%), Gaps = 11/169 (6%)

Query: 438  QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAY 496
            +PE+ W ++G  +  ++    + + E  T+ F     +   G Y ++V++ ++ E  S  
Sbjct: 850  RPELTWKKDGAEIDKNQI--NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI- 906

Query: 497  VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
                  D +I   P  P  VK  +   + + ++W  P  DG + I GY I K +  +  W
Sbjct: 907  ------DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 960

Query: 557  SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAAL 605
                +   + +   +T L+ G  Y FRV + N  G+   + +++  A +
Sbjct: 961  FTVIEHYHRTSA-TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1008



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 293  NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352
            N  L+CS+ G P+P++TW KN+V I    +  +Y + S  G+ TLEI      D   Y  
Sbjct: 1045 NATLNCSVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1101

Query: 353  SAMNVKGELSAYASVVVK 370
             A+N  G +     + VK
Sbjct: 1102 KAVNDLGTVEIECKLEVK 1119



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 638  PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
            PGPP  + + +     V L+W PP   G+  I  Y ++K +  +  W  V       S  
Sbjct: 914  PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA- 972

Query: 697  FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV 732
              + +L  G  Y FRV   N  G+ E +  T+ + V
Sbjct: 973  -TITELVIGNEYYFRVFSENMCGLSEDATMTKESAV 1007



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 35/139 (25%), Positives = 62/139 (44%), Gaps = 4/139 (2%)

Query: 1542 KTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPP 1601
            K V+ +G +  + Y++   +K+  I E  + R+   L      + G+A+NL     G P 
Sbjct: 793  KAVNAAGASEPKYYSQPILVKE--IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 850

Query: 1602 PEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTV 1661
            PE++W K + A    +  N++     T  F I     + SGKY L VK     ET+   +
Sbjct: 851  PELTW-KKDGAEIDKNQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDI 908

Query: 1662 SVFIPEEEARMAALESLKG 1680
             +       ++  +E + G
Sbjct: 909  QIIDRPGPPQIVKIEDVWG 927



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 38/147 (25%), Positives = 61/147 (41%), Gaps = 17/147 (11%)

Query: 237 EKKSRKVVIREKAERLSLRKTLEETE--------TYHAKLNED-HLLHAPEFIIK----P 283
           E    KVV + +  +L +   L E E         Y+  L    H++  P+ I+      
Sbjct: 473 ESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDAD 532

Query: 284 RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
            + TV     ++L   I+G P P+  W +    I      G+   ES     TL I+  +
Sbjct: 533 NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI--MEGSGRIRTESYPDSSTLVIDIAE 590

Query: 344 FEDTAQYRASAMNVKGELSAYASVVVK 370
            +D+  Y  +  N  GE  A+AS+ VK
Sbjct: 591 RDDSGVYHINLKNEAGE--AHASIKVK 615



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
            G    L C+V G+P P+++W+KN+ A+  D    + F         I   S  D G Y  
Sbjct: 1043 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCC 1101

Query: 1647 VVKNKYGS 1654
               N  G+
Sbjct: 1102 KAVNDLGT 1109


>gi|46049125 myosin binding protein C, slow type isoform 2 [Homo
           sapiens]
          Length = 1148

 Score =  117 bits (294), Expect = 7e-26
 Identities = 86/304 (28%), Positives = 133/304 (43%), Gaps = 40/304 (13%)

Query: 439 PEIQWYRNGVPLSP-SKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
           P+  W R    +   S  ++T    + +TL      ++D G+Y I ++     E   A+ 
Sbjct: 580 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN----EAGEAHA 635

Query: 498 FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
            ++    +    P AP      E   D+ I++W+ PA DGGSPILGYFI++ +  +  W 
Sbjct: 636 SIKVKVVDFPDPPVAPT---VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 692

Query: 558 QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRP 617
           + N    K   F    +IEG +Y  R+ AVN +GI  PS  S P   L            
Sbjct: 693 RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPL------------ 740

Query: 618 SAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKC 676
                              V  PPT L+V   T + V + W+PP   G  G+  Y +E C
Sbjct: 741 ------------------AVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782

Query: 677 EAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
             GTE+W   N +L +   +F +  L        RV+  N+AG  EP   ++  +V + +
Sbjct: 783 FEGTEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841

Query: 737 DIPK 740
           + PK
Sbjct: 842 EPPK 845



 Score =  114 bits (284), Expect = 1e-24
 Identities = 180/759 (23%), Positives = 287/759 (37%), Gaps = 125/759 (16%)

Query: 287  TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
            T +  E V+L C ++   +  V W+KN   I +     +Y I      H L I G    D
Sbjct: 377  TAYCGERVELECEVSE-DDANVKWFKNGEEI-IPGPKSRYRIRVEGKKHILIIEGATKAD 434

Query: 347  TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
             A+Y  S M   G+ SA  SV +K                  PL   +TP          
Sbjct: 435  AAEY--SVMTTGGQSSAKLSVDLK------------------PLKI-LTPL--------- 464

Query: 407  FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                         +T++LG  + +  EI    P  +W +NG+P+  S  ++ +  G    
Sbjct: 465  -----------TDQTVNLGKEICLKCEISENIPG-KWTKNGLPVQESDRLKVVHKGRIHK 512

Query: 467  LTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYI 526
            L  ++   EDEG         +Y     AY     A   +   P   LD   L+A+    
Sbjct: 513  LVIANALTEDEG---------DYVFAPDAYNVTLPAKVHVIDPPKIILDG--LDADNTVT 561

Query: 527  IISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRA 586
            +I+  +  ++   PI G    K       WS+ +      A    +G I   SY      
Sbjct: 562  VIAGNKLRLE--IPISGEPPPKA-----MWSRGDK-----AIMEGSGRIRTESYPDSSTL 609

Query: 587  VNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSV 646
            V    I    R    V  ++   +A       A  + ++ V +        P PP   +V
Sbjct: 610  V----IDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVD-------FPDPPVAPTV 653

Query: 647  TEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEG 705
            TE    + +++W+PP   G   I+ YF+E+ +  +  W R+N +L  K   F    + EG
Sbjct: 654  TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEG 712

Query: 706  KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESK 763
             +Y  R+   N+ G+ +PS  +   V    L +   P  +     TDT+V + W   +  
Sbjct: 713  VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769

Query: 764  DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823
             A  L GY +E    G+  W   N + +  ++FT  GL T      RV+AVNAAG SE  
Sbjct: 770  GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829

Query: 824  QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPS 883
              S+ I VK  I              EP  +   R           +   L+     KP 
Sbjct: 830  YYSQPILVKEII--------------EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875

Query: 884  LPSSSQNLGQTEVSKVSETVQEELTPP---PQKAAPQGKSKSDPLKKKTDR--------- 931
             P  +      E+ K    ++   T      +KA      K D L+ K D+         
Sbjct: 876  -PELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYD-LQVKVDKFVETASIDI 933

Query: 932  ---APPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
                 P PP  +   + + +++ L W  P   G A ITGY +   +  D    +W    +
Sbjct: 934  QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTI---QKADKKSMEWFTV-I 989

Query: 989  KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
            +     +  I+ L     Y F+V + NM GL   + +++
Sbjct: 990  EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 119/536 (22%), Positives = 202/536 (37%), Gaps = 65/536 (12%)

Query: 934  PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
            P PP   T  E   D  ++ W+ P   GG+ I GY++  ++       +W   N     E
Sbjct: 645  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS---RWMRLNFDLCKE 701

Query: 994  EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
              ++   + E + Y+ ++ A+N  G+  PS  S  F      +AV  PP  L    V   
Sbjct: 702  TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTVDSVTDT 757

Query: 1054 SLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVF 1113
            ++ ++W+PP H G   + GY   L+      + W   N+  I      + GL        
Sbjct: 758  TVTMRWRPPDHIGAAGLDGYV--LEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFV 815

Query: 1114 RVRAINQAGVGKPSDLAGPVVAE----------TRPGTKEVVVNVDDDGVISLNFECDKM 1163
            RV+A+N AG  +P   + P++ +           R   +  +  V +   + + F+    
Sbjct: 816  RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ---G 872

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
             P+ E +W KD     D  ++ + +    T +  +       G Y   V   D    +  
Sbjct: 873  KPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQV-KVDKFVETAS 930

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV-NYIFN-- 1280
            ID + + R          P  P    + +E +    V       K  GNA +  Y     
Sbjct: 931  IDIQIIDR----------PGPP--QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978

Query: 1281 EKEIFEGPKYKMHIDRNTGII-------EMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1333
            +K+  E      H  R +  I       E +     +   G      +D   T  S V+ 
Sbjct: 979  DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL----SEDATMTKESAVIA 1034

Query: 1334 -VGDVFKK-LQKEAEFQRQEWIRKQGPHFVEYL--SWEVTGECNVLLKCKVANIKKETHI 1389
              G ++K  + ++ +F        + P F + L  ++ + G  N  L C V    K   I
Sbjct: 1035 RDGKIYKNPVYEDFDF-------SEAPMFTQPLVNTYAIAG-YNATLNCSVRGNPK-PKI 1085

Query: 1390 VWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
             W K++  I  D ++      G+CTL I + S  D G Y     +D G  +   KL
Sbjct: 1086 TWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 105/445 (23%), Positives = 169/445 (37%), Gaps = 76/445 (17%)

Query: 1229 LKRLLALSHEHKFPTVPVKS-ELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEG 1287
            LKRL  +  E K      K  + A ++ + G+VRF +  E      +V +  N +EI   
Sbjct: 263  LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 320

Query: 1288 PKYKMHIDRNTGIIE-MFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAE 1346
             KY   I  + G    +F+   Q  D+  Y     D K    ST + V +    + K+ E
Sbjct: 321  TKY---IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC---STELFVREPPIMVTKQLE 374

Query: 1347 FQRQEWIRKQGPHFVEYLSWEVTGECN--VLLKCKVANIKKETHIVWYKDEREISVDEKH 1404
                                + T  C   V L+C+V+  + + ++ W+K+  EI    K 
Sbjct: 375  --------------------DTTAYCGERVELECEVS--EDDANVKWFKNGEEIIPGPKS 412

Query: 1405 DFK---DGICTLLITE-FSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIA 1460
             ++   +G   +LI E  +K DA  Y V+    +   K  + L     K L      KI 
Sbjct: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-----KPL------KIL 461

Query: 1461 LSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINE 1520
               TD  +    E I L   ++   E++   W+ NG  ++ SDR+K    G    L I  
Sbjct: 462  TPLTDQTVNLGKE-ICLKCEIS---ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 517

Query: 1521 PTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGL-- 1578
                D+G YV         +  T+       D                     +L GL  
Sbjct: 518  ALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKI-----------------ILDGLDA 556

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
             + VT+  G  L L   + G+PPP+  W + +KA+              ++   I+    
Sbjct: 557  DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAER 616

Query: 1639 ADSGKYGLVVKNKYGSETSDFTVSV 1663
             DSG Y + +KN+ G   +   V V
Sbjct: 617  DDSGVYHINLKNEAGEAHASIKVKV 641



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 38/169 (22%), Positives = 76/169 (44%), Gaps = 11/169 (6%)

Query: 438  QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAY 496
            +PE+ W ++G  +  ++    + + E  T+ F     +   G Y ++V++ ++ E  S  
Sbjct: 875  RPELTWKKDGAEIDKNQI--NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI- 931

Query: 497  VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
                  D +I   P  P  VK  +   + + ++W  P  DG + I GY I K +  +  W
Sbjct: 932  ------DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 985

Query: 557  SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAAL 605
                +   + +   +T L+ G  Y FRV + N  G+   + +++  A +
Sbjct: 986  FTVIEHYHRTSA-TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1033



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 293  NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352
            N  L+CS+ G P+P++TW KN+V I    +  +Y + S  G+ TLEI      D   Y  
Sbjct: 1070 NATLNCSVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126

Query: 353  SAMNVKGELSAYASVVVK 370
             A+N  G +     + VK
Sbjct: 1127 KAVNDLGTVEIECKLEVK 1144



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 638  PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
            PGPP  + + +     V L+W PP   G+  I  Y ++K +  +  W  V       S  
Sbjct: 939  PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA- 997

Query: 697  FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV 732
              + +L  G  Y FRV   N  G+ E +  T+ + V
Sbjct: 998  -TITELVIGNEYYFRVFSENMCGLSEDATMTKESAV 1032



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 35/139 (25%), Positives = 62/139 (44%), Gaps = 4/139 (2%)

Query: 1542 KTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPP 1601
            K V+ +G +  + Y++   +K+  I E  + R+   L      + G+A+NL     G P 
Sbjct: 818  KAVNAAGASEPKYYSQPILVKE--IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875

Query: 1602 PEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTV 1661
            PE++W K + A    +  N++     T  F I     + SGKY L VK     ET+   +
Sbjct: 876  PELTW-KKDGAEIDKNQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDI 933

Query: 1662 SVFIPEEEARMAALESLKG 1680
             +       ++  +E + G
Sbjct: 934  QIIDRPGPPQIVKIEDVWG 952



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 38/147 (25%), Positives = 61/147 (41%), Gaps = 17/147 (11%)

Query: 237 EKKSRKVVIREKAERLSLRKTLEETE--------TYHAKLNED-HLLHAPEFIIK----P 283
           E    KVV + +  +L +   L E E         Y+  L    H++  P+ I+      
Sbjct: 498 ESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDAD 557

Query: 284 RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
            + TV     ++L   I+G P P+  W +    I      G+   ES     TL I+  +
Sbjct: 558 NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI--MEGSGRIRTESYPDSSTLVIDIAE 615

Query: 344 FEDTAQYRASAMNVKGELSAYASVVVK 370
            +D+  Y  +  N  GE  A+AS+ VK
Sbjct: 616 RDDSGVYHINLKNEAGE--AHASIKVK 640



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
            G    L C+V G+P P+++W+KN+ A+  D    + F         I   S  D G Y  
Sbjct: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCC 1126

Query: 1647 VVKNKYGS 1654
               N  G+
Sbjct: 1127 KAVNDLGT 1134


>gi|45976288 myosin binding protein C, slow type isoform 1 [Homo
           sapiens]
          Length = 1171

 Score =  117 bits (294), Expect = 7e-26
 Identities = 86/304 (28%), Positives = 133/304 (43%), Gaps = 40/304 (13%)

Query: 439 PEIQWYRNGVPLSP-SKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
           P+  W R    +   S  ++T    + +TL      ++D G+Y I ++     E   A+ 
Sbjct: 580 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN----EAGEAHA 635

Query: 498 FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
            ++    +    P AP      E   D+ I++W+ PA DGGSPILGYFI++ +  +  W 
Sbjct: 636 SIKVKVVDFPDPPVAPT---VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 692

Query: 558 QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRP 617
           + N    K   F    +IEG +Y  R+ AVN +GI  PS  S P   L            
Sbjct: 693 RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPL------------ 740

Query: 618 SAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKC 676
                              V  PPT L+V   T + V + W+PP   G  G+  Y +E C
Sbjct: 741 ------------------AVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782

Query: 677 EAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
             GTE+W   N +L +   +F +  L        RV+  N+AG  EP   ++  +V + +
Sbjct: 783 FEGTEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841

Query: 737 DIPK 740
           + PK
Sbjct: 842 EPPK 845



 Score =  114 bits (284), Expect = 1e-24
 Identities = 180/759 (23%), Positives = 287/759 (37%), Gaps = 125/759 (16%)

Query: 287  TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
            T +  E V+L C ++   +  V W+KN   I +     +Y I      H L I G    D
Sbjct: 377  TAYCGERVELECEVSE-DDANVKWFKNGEEI-IPGPKSRYRIRVEGKKHILIIEGATKAD 434

Query: 347  TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
             A+Y  S M   G+ SA  SV +K                  PL   +TP          
Sbjct: 435  AAEY--SVMTTGGQSSAKLSVDLK------------------PLKI-LTPL--------- 464

Query: 407  FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                         +T++LG  + +  EI    P  +W +NG+P+  S  ++ +  G    
Sbjct: 465  -----------TDQTVNLGKEICLKCEISENIPG-KWTKNGLPVQESDRLKVVHKGRIHK 512

Query: 467  LTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYI 526
            L  ++   EDEG         +Y     AY     A   +   P   LD   L+A+    
Sbjct: 513  LVIANALTEDEG---------DYVFAPDAYNVTLPAKVHVIDPPKIILDG--LDADNTVT 561

Query: 527  IISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRA 586
            +I+  +  ++   PI G    K       WS+ +      A    +G I   SY      
Sbjct: 562  VIAGNKLRLE--IPISGEPPPKA-----MWSRGDK-----AIMEGSGRIRTESYPDSSTL 609

Query: 587  VNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSV 646
            V    I    R    V  ++   +A       A  + ++ V +        P PP   +V
Sbjct: 610  V----IDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVD-------FPDPPVAPTV 653

Query: 647  TEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEG 705
            TE    + +++W+PP   G   I+ YF+E+ +  +  W R+N +L  K   F    + EG
Sbjct: 654  TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEG 712

Query: 706  KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESK 763
             +Y  R+   N+ G+ +PS  +   V    L +   P  +     TDT+V + W   +  
Sbjct: 713  VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769

Query: 764  DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823
             A  L GY +E    G+  W   N + +  ++FT  GL T      RV+AVNAAG SE  
Sbjct: 770  GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829

Query: 824  QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPS 883
              S+ I VK  I              EP  +   R           +   L+     KP 
Sbjct: 830  YYSQPILVKEII--------------EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875

Query: 884  LPSSSQNLGQTEVSKVSETVQEELTPP---PQKAAPQGKSKSDPLKKKTDR--------- 931
             P  +      E+ K    ++   T      +KA      K D L+ K D+         
Sbjct: 876  -PELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYD-LQVKVDKFVETASIDI 933

Query: 932  ---APPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
                 P PP  +   + + +++ L W  P   G A ITGY +   +  D    +W    +
Sbjct: 934  QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTI---QKADKKSMEWFTV-I 989

Query: 989  KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
            +     +  I+ L     Y F+V + NM GL   + +++
Sbjct: 990  EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 119/536 (22%), Positives = 202/536 (37%), Gaps = 65/536 (12%)

Query: 934  PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
            P PP   T  E   D  ++ W+ P   GG+ I GY++  ++       +W   N     E
Sbjct: 645  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS---RWMRLNFDLCKE 701

Query: 994  EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
              ++   + E + Y+ ++ A+N  G+  PS  S  F      +AV  PP  L    V   
Sbjct: 702  TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTVDSVTDT 757

Query: 1054 SLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVF 1113
            ++ ++W+PP H G   + GY   L+      + W   N+  I      + GL        
Sbjct: 758  TVTMRWRPPDHIGAAGLDGYV--LEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFV 815

Query: 1114 RVRAINQAGVGKPSDLAGPVVAE----------TRPGTKEVVVNVDDDGVISLNFECDKM 1163
            RV+A+N AG  +P   + P++ +           R   +  +  V +   + + F+    
Sbjct: 816  RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ---G 872

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
             P+ E +W KD     D  ++ + +    T +  +       G Y   V   D    +  
Sbjct: 873  KPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQV-KVDKFVETAS 930

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV-NYIFN-- 1280
            ID + + R          P  P    + +E +    V       K  GNA +  Y     
Sbjct: 931  IDIQIIDR----------PGPP--QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978

Query: 1281 EKEIFEGPKYKMHIDRNTGII-------EMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1333
            +K+  E      H  R +  I       E +     +   G      +D   T  S V+ 
Sbjct: 979  DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL----SEDATMTKESAVIA 1034

Query: 1334 -VGDVFKK-LQKEAEFQRQEWIRKQGPHFVEYL--SWEVTGECNVLLKCKVANIKKETHI 1389
              G ++K  + ++ +F        + P F + L  ++ + G  N  L C V    K   I
Sbjct: 1035 RDGKIYKNPVYEDFDF-------SEAPMFTQPLVNTYAIAG-YNATLNCSVRGNPK-PKI 1085

Query: 1390 VWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
             W K++  I  D ++      G+CTL I + S  D G Y     +D G  +   KL
Sbjct: 1086 TWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 105/445 (23%), Positives = 169/445 (37%), Gaps = 76/445 (17%)

Query: 1229 LKRLLALSHEHKFPTVPVKS-ELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEG 1287
            LKRL  +  E K      K  + A ++ + G+VRF +  E      +V +  N +EI   
Sbjct: 263  LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 320

Query: 1288 PKYKMHIDRNTGIIE-MFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAE 1346
             KY   I  + G    +F+   Q  D+  Y     D K    ST + V +    + K+ E
Sbjct: 321  TKY---IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC---STELFVREPPIMVTKQLE 374

Query: 1347 FQRQEWIRKQGPHFVEYLSWEVTGECN--VLLKCKVANIKKETHIVWYKDEREISVDEKH 1404
                                + T  C   V L+C+V+  + + ++ W+K+  EI    K 
Sbjct: 375  --------------------DTTAYCGERVELECEVS--EDDANVKWFKNGEEIIPGPKS 412

Query: 1405 DFK---DGICTLLITE-FSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIA 1460
             ++   +G   +LI E  +K DA  Y V+    +   K  + L     K L      KI 
Sbjct: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-----KPL------KIL 461

Query: 1461 LSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINE 1520
               TD  +    E I L   ++   E++   W+ NG  ++ SDR+K    G    L I  
Sbjct: 462  TPLTDQTVNLGKE-ICLKCEIS---ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 517

Query: 1521 PTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGL-- 1578
                D+G YV         +  T+       D                     +L GL  
Sbjct: 518  ALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKI-----------------ILDGLDA 556

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
             + VT+  G  L L   + G+PPP+  W + +KA+              ++   I+    
Sbjct: 557  DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAER 616

Query: 1639 ADSGKYGLVVKNKYGSETSDFTVSV 1663
             DSG Y + +KN+ G   +   V V
Sbjct: 617  DDSGVYHINLKNEAGEAHASIKVKV 641



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 38/169 (22%), Positives = 76/169 (44%), Gaps = 11/169 (6%)

Query: 438  QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAY 496
            +PE+ W ++G  +  ++    + + E  T+ F     +   G Y ++V++ ++ E  S  
Sbjct: 875  RPELTWKKDGAEIDKNQI--NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI- 931

Query: 497  VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
                  D +I   P  P  VK  +   + + ++W  P  DG + I GY I K +  +  W
Sbjct: 932  ------DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 985

Query: 557  SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAAL 605
                +   + +   +T L+ G  Y FRV + N  G+   + +++  A +
Sbjct: 986  FTVIEHYHRTSA-TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1033



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 293  NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352
            N  L+CS+ G P+P++TW KN+V I    +  +Y + S  G+ TLEI      D   Y  
Sbjct: 1070 NATLNCSVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126

Query: 353  SAMNVKGELSAYASVVVK 370
             A+N  G +     + VK
Sbjct: 1127 KAVNDLGTVEIECKLEVK 1144



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 638  PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
            PGPP  + + +     V L+W PP   G+  I  Y ++K +  +  W  V       S  
Sbjct: 939  PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA- 997

Query: 697  FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV 732
              + +L  G  Y FRV   N  G+ E +  T+ + V
Sbjct: 998  -TITELVIGNEYYFRVFSENMCGLSEDATMTKESAV 1032



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 35/139 (25%), Positives = 62/139 (44%), Gaps = 4/139 (2%)

Query: 1542 KTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPP 1601
            K V+ +G +  + Y++   +K+  I E  + R+   L      + G+A+NL     G P 
Sbjct: 818  KAVNAAGASEPKYYSQPILVKE--IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875

Query: 1602 PEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTV 1661
            PE++W K + A    +  N++     T  F I     + SGKY L VK     ET+   +
Sbjct: 876  PELTW-KKDGAEIDKNQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDI 933

Query: 1662 SVFIPEEEARMAALESLKG 1680
             +       ++  +E + G
Sbjct: 934  QIIDRPGPPQIVKIEDVWG 952



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 38/147 (25%), Positives = 61/147 (41%), Gaps = 17/147 (11%)

Query: 237 EKKSRKVVIREKAERLSLRKTLEETE--------TYHAKLNED-HLLHAPEFIIK----P 283
           E    KVV + +  +L +   L E E         Y+  L    H++  P+ I+      
Sbjct: 498 ESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDAD 557

Query: 284 RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
            + TV     ++L   I+G P P+  W +    I      G+   ES     TL I+  +
Sbjct: 558 NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI--MEGSGRIRTESYPDSSTLVIDIAE 615

Query: 344 FEDTAQYRASAMNVKGELSAYASVVVK 370
            +D+  Y  +  N  GE  A+AS+ VK
Sbjct: 616 RDDSGVYHINLKNEAGE--AHASIKVK 640



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
            G    L C+V G+P P+++W+KN+ A+  D    + F         I   S  D G Y  
Sbjct: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCC 1126

Query: 1647 VVKNKYGS 1654
               N  G+
Sbjct: 1127 KAVNDLGT 1134


>gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
          Length = 1274

 Score =  115 bits (289), Expect = 3e-25
 Identities = 85/279 (30%), Positives = 120/279 (43%), Gaps = 39/279 (13%)

Query: 463 ERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEAN 522
           +R+  T     KEDEG+YT+ V+     +Q +  V V D    +  APAAP   K     
Sbjct: 732 DRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVID----VPDAPAAP---KISNVG 784

Query: 523 KDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIF 582
           +D   + W+ PA DGG PILGY +++ +  +  W + N   ++        +IEG  Y  
Sbjct: 785 EDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEM 844

Query: 583 RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
           RV AVN +G+  PS  S+P   + P                              P  PT
Sbjct: 845 RVYAVNAIGMSRPSPASQPFMPIGP------------------------------PSEPT 874

Query: 643 DLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKCEAGTENWQRVNTELPVKSPRFALFD 701
            L+V + + + V L W+PP + G  G+  Y VE C  G   W      L  +     + D
Sbjct: 875 HLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL-TEHTSILVKD 933

Query: 702 LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 740
           L  G    FRVR  N AG G P   TE   V + L  P+
Sbjct: 934 LPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPR 972



 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 53/189 (28%), Positives = 84/189 (44%), Gaps = 9/189 (4%)

Query: 948  DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY 1007
            DS  + W+ P   GG  I GY +  ++       +W   N   + E +++   + E +VY
Sbjct: 786  DSCTVQWEPPAYDGGQPILGYILERKKKKSY---RWMRLNFDLIQELSHEARRMIEGVVY 842

Query: 1008 QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 1067
            + +V A+N  G+  PS  S+ F      I  P  P  L   +V   ++ L+W+PP   G 
Sbjct: 843  EMRVYAVNAIGMSRPSPASQPF----MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGA 898

Query: 1068 TPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS 1127
              + GY V+       E  W    +   ++  + V+ L  G   +FRVRA N AG G P 
Sbjct: 899  GGLDGYSVEYCPEGCSE--WVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPV 956

Query: 1128 DLAGPVVAE 1136
                PV  +
Sbjct: 957  TTTEPVTVQ 965



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 86/401 (21%), Positives = 157/401 (39%), Gaps = 26/401 (6%)

Query: 637  VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSP 695
            VP  P    ++        + W+PP   G + I+ Y +E+ +  +  W R+N +L ++  
Sbjct: 771  VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDL-IQEL 829

Query: 696  RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSV 755
                  + EG  Y  RV   N+ G+  PS A++  +    +  P  P  +     +DT+V
Sbjct: 830  SHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTV 886

Query: 756  VVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRA 813
             + W   E   A  L GY +E    G  +W        + +      L TG   +FRVRA
Sbjct: 887  SLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRA 946

Query: 814  VNAAGLSEYSQDSEAIEV-------KAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASP 866
             N AG       +E + V       +  +   +   +   + +    L   +G+      
Sbjct: 947  HNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVT 1006

Query: 867  PTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLK 926
             T +   L G + +  + P+ +    +      S T Q  +           + K+  + 
Sbjct: 1007 WTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV------RIENMEDKATLVL 1060

Query: 927  KKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREA 986
            +  D+  PSPP D+   +++  ++ L WK P  +G  E+ GY V   +  D    +W   
Sbjct: 1061 QVVDK--PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV---QKADKKTMEWFTV 1115

Query: 987  NVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
             ++        +  L     Y F+V + NM G    +A ++
Sbjct: 1116 -LEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTK 1155



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 70/293 (23%), Positives = 101/293 (34%), Gaps = 71/293 (24%)

Query: 508  GAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFA 567
            G P+ P  +   + +   + + W+ P   G   + GY ++ C  G   W        +  
Sbjct: 868  GPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927

Query: 568  RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARL-------------- 613
               V  L  G   +FRVRA N  G G P   +EPV   +  ++ RL              
Sbjct: 928  SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV 987

Query: 614  ------------KSRPSAPWT--GQIIVTEE-----EPSEGIV----------------- 637
                        K RP   WT  GQ +  EE      P++ I+                 
Sbjct: 988  GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1047

Query: 638  ------------------PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEA 678
                              P PP DL VT+A    V L WKPP   G+  +  Y V+K + 
Sbjct: 1048 RIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADK 1107

Query: 679  GTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTV 731
             T  W  V      +     + +L  G  Y FRV   N  G  + +  T+  V
Sbjct: 1108 KTMEWFTVLEH--YRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPV 1158



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 43/120 (35%), Positives = 62/120 (51%), Gaps = 4/120 (3%)

Query: 1036 IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 1095
            I VP  P + K S V +DS  +QW+PP + G  P+ GY ++ K  K K  +W  LN   I
Sbjct: 769  IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERK--KKKSYRWMRLNFDLI 826

Query: 1096 KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG--TKEVVVNVDDDGV 1153
            + +  + R + EGV Y  RV A+N  G+ +PS  + P +    P   T   V +V D  V
Sbjct: 827  QELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTV 886



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 77/336 (22%), Positives = 131/336 (38%), Gaps = 69/336 (20%)

Query: 1374 VLLKCKVANIKKETHIVWYKDEREISVDEKHDF---KDGICT-LLITEFSKKDAGIYEVI 1429
            V  +C+V+  ++   + W KD  E++ +E   +   KDG    L+I E   +DAG Y + 
Sbjct: 471  VEFECEVS--EEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALC 528

Query: 1430 LKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLK 1489
                +        L +   +E  +EV + IA    DL + +  + +          E+++
Sbjct: 529  TSGGQA-------LAELIVQEKKLEVYQSIA----DLMVGAKDQAVFKCEVSD---ENVR 574

Query: 1490 VNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY--VMELFDGKTGHQKTVDLS 1547
              W  NG  +    R+K    G    L I++ TP D+  Y  V E F          +LS
Sbjct: 575  GVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGF--------ACNLS 626

Query: 1548 GQAYDEAYAEFQRLKQAAIAEKNRARVL----GGLPDVVTIQEGKALNLTCNVWGDPPPE 1603
             + +      F  +K   +  +   ++     G +PD + +  G  L L   + GDP P 
Sbjct: 627  AKLH------FMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680

Query: 1604 VSWLKN---------------------------EKALASDDHCNLKFEAGRT-AYFTING 1635
            V W K                            +K L  +    ++ E  +  + FT+ G
Sbjct: 681  VIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEG 740

Query: 1636 VSTADSGKYGLVVKNKYGSETSDFTVSVF-IPEEEA 1670
                D G Y + VKN  G +  + TV V  +P+  A
Sbjct: 741  AEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPA 776



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 50/200 (25%), Positives = 79/200 (39%), Gaps = 22/200 (11%)

Query: 1039 PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1098
            P PP  L+ ++    ++ L+WKPP   G T + GY V  ++A  K  +W  + E   +  
Sbjct: 1066 PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV--QKADKKTMEWFTVLE-HYRRT 1122

Query: 1099 YLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG------------------ 1140
            +  V  L  G  Y FRV + N  G    +      V   RPG                  
Sbjct: 1123 HCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPS 1182

Query: 1141 -TKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKD 1199
             T+ +V      G  ++     + +PK + SW K+ +   +  R  + SK     +  + 
Sbjct: 1183 FTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRK 1242

Query: 1200 LGMDDLGIYSCDVTDTDGIA 1219
                D GIY C  T+  G A
Sbjct: 1243 PCPFDGGIYVCRATNLQGEA 1262



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 42/168 (25%), Positives = 70/168 (41%), Gaps = 14/168 (8%)

Query: 438  QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
            +P++ W + G PL+  + V    S     L      +   G Y + VR+    ++ +  +
Sbjct: 1002 RPQVTWTKEGQPLAGEE-VSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVL 1060

Query: 498  FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
             V D        P+ P D++  +A    + + WK P   G + + GY + K +  T  W 
Sbjct: 1061 QVVDK-------PSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF 1113

Query: 558  QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVS---EPV 602
               +   +     V  LI G  Y FRV + N   +GF  R +   EPV
Sbjct: 1114 TVLE-HYRRTHCVVPELIIGNGYYFRVFSQNM--VGFSDRAATTKEPV 1158



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 101/539 (18%), Positives = 183/539 (33%), Gaps = 83/539 (15%)

Query: 305 EPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAY 364
           +  V W KN   I +  +  KYI ES     TL I+ C   D A Y+     V G     
Sbjct: 391 DAEVKWLKNGQEIQMSGS--KYIFESIGAKRTLTISQCSLADDAAYQC----VVGGEKCS 444

Query: 365 ASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSL 424
             + VK                T PL                           E + + +
Sbjct: 445 TELFVKE----------PPVLITRPL---------------------------EDQLVMV 467

Query: 425 GCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWS--GERATLTFSHLNKEDEGLYTI 482
           G RV    E+     +++W ++GV L+  +  +  +   G+R  L  +    ED G Y +
Sbjct: 468 GQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYAL 527

Query: 483 RVRMGE-----YYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDG 537
               G+       ++    V+   AD  +     A    +  + N   + +   +  V  
Sbjct: 528 CTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPD 587

Query: 538 GSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRA-------VNKM 590
               + +     ++  D  +  ++    F        +  + +   V+          K+
Sbjct: 588 SRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKI 647

Query: 591 GIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEAT 650
            +  P R+ + +  +     A  K R   P +G       +P+  ++       ++T+  
Sbjct: 648 HLDCPGRIPDTIVVV-----AGNKLRLDVPISG-------DPAPTVI----WQKAITQGN 691

Query: 651 RSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCF 710
           ++    +   P   G      F +K    TE   RV  E       F +    +     +
Sbjct: 692 KAPARPAPDAPEDTGDSDEWVFDKKLLCETEG--RVRVETTKDRSIFTVEGAEKEDEGVY 749

Query: 711 RVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESK--DAKEL 768
            V   N  G  + +   +V      +D+P AP     S   + S  V WE       + +
Sbjct: 750 TVTVKNPVGEDQVNLTVKV------IDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI 803

Query: 769 VGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 827
           +GY +E     S +W   N + ++        ++ G  Y  RV AVNA G+S  S  S+
Sbjct: 804 LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQ 862



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 3/101 (2%)

Query: 933  PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVS 992
            PPS P  +   +    ++ L W+ P+++G   + GY V Y    +G   +W  A      
Sbjct: 869  PPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEY--CPEGC-SEWVAALQGLTE 925

Query: 993  EEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE 1033
              +  + +L       F+V A NMAG GAP   +E    +E
Sbjct: 926  HTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQE 966



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 5/86 (5%)

Query: 276  APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
            AP F     + +V       L C++ G P+P+++W+KN + +   A   ++ + S+ G+ 
Sbjct: 1180 APSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDA---RFRMFSKQGVL 1236

Query: 336  TLEI-NGCDFEDTAQYRASAMNVKGE 360
            TLEI   C F D   Y   A N++GE
Sbjct: 1237 TLEIRKPCPF-DGGIYVCRATNLQGE 1261



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 6/78 (7%)

Query: 408 DDKFDVSFGREGET---MSLGCRVVITPEIKHFQPEIQWYRNG--VPLSPSKWVQTLWSG 462
           D+K   +F ++ E    +S G ++ +T E+     E++W +NG  + +S SK++     G
Sbjct: 358 DEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFES-IG 416

Query: 463 ERATLTFSHLNKEDEGLY 480
            + TLT S  +  D+  Y
Sbjct: 417 AKRTLTISQCSLADDAAY 434



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 22/81 (27%), Positives = 29/81 (35%), Gaps = 1/81 (1%)

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
            G    L C V G P P++SW KN   L  D    + F         I      D G Y  
Sbjct: 1195 GYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVLTLEIRKPCPFDGGIYVC 1253

Query: 1647 VVKNKYGSETSDFTVSVFIPE 1667
               N  G    +  + V +P+
Sbjct: 1254 RATNLQGEARCECRLEVRVPQ 1274



 Score = 31.6 bits (70), Expect = 6.8
 Identities = 27/120 (22%), Positives = 44/120 (36%), Gaps = 24/120 (20%)

Query: 422 MSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYT 481
           ++ G   V   E +    +++W R G  +S S        G R TLT   +   D+G Y 
Sbjct: 21  VAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYA 80

Query: 482 IRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANK-DYIIISWKQPAVDGGSP 540
           +                       I G+     D+K +EA K + ++     PA   G+P
Sbjct: 81  V-----------------------IAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAP 117



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 25/90 (27%), Positives = 34/90 (37%), Gaps = 1/90 (1%)

Query: 1559 QRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDH 1618
            +RLK     EK        L     + +G  + LT  +  D   EV WLKN + +     
Sbjct: 350  KRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVEL-ADHDAEVKWLKNGQEIQMSGS 408

Query: 1619 CNLKFEAGRTAYFTINGVSTADSGKYGLVV 1648
              +    G     TI+  S AD   Y  VV
Sbjct: 409  KYIFESIGAKRTLTISQCSLADDAAYQCVV 438


>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
            precursor [Homo sapiens]
          Length = 1898

 Score =  114 bits (286), Expect = 6e-25
 Identities = 187/871 (21%), Positives = 324/871 (37%), Gaps = 134/871 (15%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P   + P+   V +     + C+  G P+P ++W+K+ +P++   + G+ I + R G   
Sbjct: 135  PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGR-IKQLRSG--A 191

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTP 396
            L+I   +  D  +Y   A N  G                   TR+ A     P +  V  
Sbjct: 192  LQIESSEESDQGKYECVATNSAG-------------------TRYSA-----PANLYVRV 227

Query: 397  YGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWV 456
               A RF I    +  +     G +++L C  V  P      P ++W      L+    +
Sbjct: 228  RRVAPRFSIPPSSQEVMP----GGSVNLTCVAVGAP-----MPYVKWMMGAEELTKEDEM 278

Query: 457  QTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEI--EGAPAAPL 514
                   R  L  S++           VR   Y     + + + +A A++  +  P  P+
Sbjct: 279  PV----GRNVLELSNV-----------VRSANYTCVAISSLGMIEATAQVTVKALPKPPI 323

Query: 515  DVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGL 574
            D+   E     + ++W         P+  Y I     GT+   Q  D  V   R+ + GL
Sbjct: 324  DLVVTETTATSVTLTWDS---GNSEPVTYYGIQYRAAGTEGPFQEVDG-VATTRYSIGGL 379

Query: 575  IEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSE 634
                 Y FRV AVN +G G PS           A +AR         TG     E+ PS 
Sbjct: 380  SPFSEYAFRVLAVNSIGRGPPSE----------AVRAR---------TG-----EQAPS- 414

Query: 635  GIVPGPPTDLSVTEATRSYVVLSWKPPGQ-----RGHEGIMYFVEKCEAGTENWQRVNTE 689
                 PP  +     + S +++ W+PP +     RG+   +Y+          W + NT+
Sbjct: 415  ----SPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYR--VYYTPDSRRPPNAWHKHNTD 468

Query: 690  LPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSR 749
              + +    +  L  G +Y  RV    + G G PS   +V     +  +P  P       
Sbjct: 469  AGLLT---TVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKT---QQGVPAQPADFQAEV 522

Query: 750  NTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIF 809
             +DT + +SW      + ++   +  +     +      +P   S +T   L     Y F
Sbjct: 523  ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT--SSYTLEDLKPDTLYRF 580

Query: 810  RVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTF 869
            ++ A +  G+  ++   EA   ++         +C ++    G  T    RV    PP  
Sbjct: 581  QLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSM----GSTTV---RVSWVPPPAD 633

Query: 870  QKDALL-----------GSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQG 918
             ++ ++           G    +  +   S+     ++  + +  +  +          G
Sbjct: 634  SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 693

Query: 919  KSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWK--QPDKIGGAEITGYYVNYREVI 976
               S  L +  +  P  PP  +        ++ + WK   P K  G +I GY V Y  + 
Sbjct: 694  PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHG-QIRGYQVTYVRLE 752

Query: 977  DGVP-GKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWT 1035
            +G P G     +V     +   IS L     Y   VAA    G GA S      K    T
Sbjct: 753  NGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKP----KIVTTT 808

Query: 1036 IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWR-GLNEAA 1094
             AVPG P ++  S    ++ +LQW PP       + G  +  +    + D+ R    +  
Sbjct: 809  GAVPGRP-TMMISTTAMNTALLQWHPP-----KELPGELLGYRLQYCRADEARPNTIDFG 862

Query: 1095 IKNVYLKVRGLKEGVSYVFRVRAINQAGVGK 1125
              + +  V GL +G +Y+FR+ A N+AG+G+
Sbjct: 863  KDDQHFTVTGLHKGTTYIFRLAAKNRAGLGE 893



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 74/284 (26%), Positives = 115/284 (40%), Gaps = 27/284 (9%)

Query: 929  TDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
            T +A P PP D+   E+   S+ L W   D      +T Y + YR    G  G ++E  V
Sbjct: 314  TVKALPKPPIDLVVTETTATSVTLTW---DSGNSEPVTYYGIQYRAA--GTEGPFQE--V 366

Query: 989  KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCS 1048
              V+   Y I  L     Y F+V A+N  G G PS   E  +      A   PP  ++  
Sbjct: 367  DGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPS---EAVRARTGEQAPSSPPRRVQAR 423

Query: 1049 EVRKDSLVLQWKPPVHSGRTPVTGYFVDLK-EAKAKEDQWRGLNEAAIKNVYLKVRGLKE 1107
             +   ++++QW+PP       V GY V    +++   + W   N  A   +   V  L  
Sbjct: 424  MLSASTMLVQWEPPEEPNGL-VRGYRVYYTPDSRRPPNAWHKHNTDA--GLLTTVGSLLP 480

Query: 1108 GVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGT----KEVVVNVDDDGVISLNFECDKM 1163
            G++Y  RV A    G G PS     +  +T+ G      +    V+ D  I L++    +
Sbjct: 481  GITYSLRVLAFTAVGDGPPSP---TIQVKTQQGVPAQPADFQAEVESDTRIQLSW----L 533

Query: 1164 TPKSE--FSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDL 1205
             P  E    +   Y + ED  +    +    +  T +DL  D L
Sbjct: 534  LPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTL 577



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 186/896 (20%), Positives = 308/896 (34%), Gaps = 185/896 (20%)

Query: 276  APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
            AP F I P S  V    +V L C   G P P V W      +           E   G +
Sbjct: 231  APRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED-------EMPVGRN 283

Query: 336  TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRY-KGEFDETRFHAGASTMPLSFG- 393
             LE++  +   +A Y   A++  G + A A V VK   K   D       A+++ L++  
Sbjct: 284  VLELS--NVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDS 341

Query: 394  -----VTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGV 448
                 VT YG   R           + G EG    +         I    P  ++    +
Sbjct: 342  GNSEPVTYYGIQYR-----------AAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVL 390

Query: 449  PLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEG 508
                   V ++  G  +                +R R GE                +   
Sbjct: 391  A------VNSIGRGPPSE--------------AVRARTGE----------------QAPS 414

Query: 509  APAAPLDVKCLEANKDYIIISWKQPAVDGGSPILG---YFIDKCEVGTDSWSQCNDTPVK 565
            +P   +  + L A+   +++ W+ P    G  + G   Y+        ++W + N     
Sbjct: 415  SPPRRVQARMLSAST--MLVQWEPPEEPNGL-VRGYRVYYTPDSRRPPNAWHKHNTDAGL 471

Query: 566  FARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQI 625
                 V  L+ G +Y  RV A   +G G             P+   ++K++   P     
Sbjct: 472  LT--TVGSLLPGITYSLRVLAFTAVGDG------------PPSPTIQVKTQQGVP----- 512

Query: 626  IVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQR 685
                           P D      + + + LSW  P Q     IMY +    A  E+ Q 
Sbjct: 513  -------------AQPADFQAEVESDTRIQLSWLLPPQ--ERIIMYELVYWAAEDEDQQH 557

Query: 686  VNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKI 745
              T  P  S  + L DL     Y F++   +  GVG  +   E          P  P K+
Sbjct: 558  KVTFDPTSS--YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAP--PQKV 613

Query: 746  IPSRNTDTSVVVSW--EESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVT 803
            +      T+V VSW    +     ++  Y  A  A  G+            R    G+  
Sbjct: 614  MCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGE---------DRGRHVVDGISR 664

Query: 804  GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPAL----SDEPGG------ 853
              S      + +  GL ++++    + V+A    G  P+  P L     D P G      
Sbjct: 665  EHS------SWDLVGLEKWTE--YRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVE 716

Query: 854  ---LTASRGRVHEASP-PTFQKDALLGSKPNKPSL----PSSSQNLGQTEVSKVSETVQE 905
               L ++   V+   P P+ Q   + G +     L    P     +    +++  ET   
Sbjct: 717  VEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTIS 776

Query: 906  ELTPPPQKAAPQGK-------SKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPD 958
             LTP    +            ++S P    T  A P  P  +    +  ++ +L W  P 
Sbjct: 777  GLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAM-NTALLQWHPPK 835

Query: 959  KIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAG 1018
            ++ G E+ GY + Y    +  P            ++ + ++ L +   Y F++AA N AG
Sbjct: 836  ELPG-ELLGYRLQYCRADEARPNTIDFGK----DDQHFTVTGLHKGTTYIFRLAAKNRAG 890

Query: 1019 LGAPSAVSECFKCEEWTIAVP-----GPPHSLKCSEVRKDSLVLQWKPPVHSGRT-PVTG 1072
            LG      E F+ E   I  P     G P +L  + +   +  L W PPV + R   +  
Sbjct: 891  LG------EEFEKE---IRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIIS 941

Query: 1073 YFVDLKEAKAKEDQWRGLNEAAIKNVYLKVR----GLKEGVSYVFRVRAINQAGVG 1124
            Y V  ++  ++++         ++N+    R    GLK   +Y  +VRA    G G
Sbjct: 942  YTVVFRDINSQQE---------LQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSG 988



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 66/254 (25%), Positives = 99/254 (38%), Gaps = 51/254 (20%)

Query: 527  IISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFAR----FPVTGLIEGRSYIF 582
            ++ W  P    G  +LGY +  C        +     + F +    F VTGL +G +YIF
Sbjct: 828  LLQWHPPKELPGE-LLGYRLQYCRA-----DEARPNTIDFGKDDQHFTVTGLHKGTTYIF 881

Query: 583  RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
            R+ A N+ G+G            +  EK             +I   E+ PS     G P 
Sbjct: 882  RLAAKNRAGLG------------EEFEK-------------EIRTPEDLPS-----GFPQ 911

Query: 643  DLSVTEATRSYVVLSWKPP--GQRGHEGIMYFVEKCEAGT-ENWQRVNTELPVKSPRFAL 699
            +L VT  T S   L+W PP   +R    I Y V   +  + +  Q + T+      RF L
Sbjct: 912  NLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITTD-----TRFTL 966

Query: 700  FDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSW 759
              L    +Y  +VR   S G G  S + +   +  +    K       +    TSV++SW
Sbjct: 967  TGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAK---NFRVAAAMKTSVLLSW 1023

Query: 760  EESKDAKELVGYYI 773
            E     K  V + I
Sbjct: 1024 EVPDSYKSAVPFKI 1037



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
            P +  +++ +   + C   G+P PE+SW K+   +      N + +  R+    I     
Sbjct: 141  PQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPV-DPATSNGRIKQLRSGALQIESSEE 199

Query: 1639 ADSGKYGLVVKNKYGSETS 1657
            +D GKY  V  N  G+  S
Sbjct: 200  SDQGKYECVATNSAGTRYS 218



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 26/109 (23%), Positives = 44/109 (40%), Gaps = 3/109 (2%)

Query: 1578 LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
            +P+  T   G   +  C   G+P P ++W+K  K ++S     ++F+ G  +   I  + 
Sbjct: 38   VPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLR 97

Query: 1638 T-ADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGKKAK 1685
               D   Y     N  G   +   +SV   EEE       S+  G + K
Sbjct: 98   VQRDEAIYECTATNSLGEINTSAKLSVL--EEEQLPPGFPSIDMGPQLK 144



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 55/263 (20%), Positives = 101/263 (38%), Gaps = 42/263 (15%)

Query: 1389 IVWYKDEREISVD--EKHDFKDGICTLLITEFSK--KDAGIYEVILKDDRGKDKSRLKL- 1443
            I W K  +++S    E  +F DG  ++L  +  +  +D  IYE    +  G+  +  KL 
Sbjct: 64   ITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLS 123

Query: 1444 ------VDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGS 1497
                  +   F  + M    K+   A    +   A G      ++++ + L V+ + +  
Sbjct: 124  VLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGG-NPDPEISWFKDFLPVDPATSNG 182

Query: 1498 AIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAE 1557
             I+   ++++G       LQI     +D+GKY               + +G  Y      
Sbjct: 183  RIK---QLRSGA------LQIESSEESDQGKYECV----------ATNSAGTRYSAPANL 223

Query: 1558 FQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDD 1617
            + R+++ A             P    +  G ++NLTC   G P P V W+   + L  +D
Sbjct: 224  YVRVRRVAPR-------FSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED 276

Query: 1618 HCNLKFEAGRTAYFTINGVSTAD 1640
                +   GR      N V +A+
Sbjct: 277  ----EMPVGRNVLELSNVVRSAN 295


>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
            precursor [Homo sapiens]
          Length = 1903

 Score =  114 bits (284), Expect = 1e-24
 Identities = 195/891 (21%), Positives = 335/891 (37%), Gaps = 143/891 (16%)

Query: 268  LNEDHLLHA-PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPG-- 324
            L ED +    P   + P+   V       + C+ +G P+P +TW+K+ +P++   N G  
Sbjct: 116  LREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRI 175

Query: 325  KYIIESRYG----MHTLEINGCDFEDTAQYRASAMNVKG-ELSAYASVVVKRYKGEFDET 379
            K +     G       L+I   +  D  +Y   A N  G   SA A++ V+    E  E 
Sbjct: 176  KQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVR----ELREV 231

Query: 380  RFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQP 439
            R       +P  F + P  +    EI             G ++++ C  V +P      P
Sbjct: 232  R------RVPPRFSIPPTNH----EI-----------MPGGSVNITCVAVGSP-----MP 265

Query: 440  EIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFV 499
             ++W      L+P   +       R  L  + + +           +G         V  
Sbjct: 266  YVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQSANYTCVAMSTLG---------VIE 312

Query: 500  RDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPI-LGYFIDKCEVGTDSWSQ 558
              A   ++  P  P      E+    I ++W     D G+P  + Y+I + +        
Sbjct: 313  AIAQITVKALPKPPGTPVVTESTATSITLTW-----DSGNPEPVSYYIIQHKPKNSEELY 367

Query: 559  CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
                 V   R+ V GL     Y FRV AVN +G G P   SEPV                
Sbjct: 368  KEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPP---SEPVLTQ------------- 411

Query: 619  APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQ-----RGHEGIMYFV 673
                     +E+ PS       P D+     + + +++ WK P +     +G+   +Y+ 
Sbjct: 412  --------TSEQAPSSA-----PRDVQARMLSSTTILVQWKEPEEPNGQIQGYR--VYYT 456

Query: 674  EKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVG 733
                    NW + N      S    + +L   K+Y  +V    S G G  S   +V    
Sbjct: 457  MDPTQHVNNWMKHNV---ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVIT-- 511

Query: 734  DKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKG 793
             +  +P  P        ++TS+++SW   + +  +  Y +       G+ +     P  G
Sbjct: 512  -QTGVPGQPLNFKAEPESETSILLSWTPPR-SDTIANYELVYKDGEHGEEQRITIEP--G 567

Query: 794  SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPA------- 846
            + +   GL     Y FR+ A +  GL   + +  A  +++          C +       
Sbjct: 568  TSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSIL 627

Query: 847  LSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKP----SLPSSS-----QNLGQTEVS 897
            +S +P  +    G + E S     K   +  + +KP     +PS +     + L +    
Sbjct: 628  VSWQPPPVEKQNGIITEYS----IKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEY 683

Query: 898  KVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQ- 956
            +++ T   ++ P P+  +   ++  D         P  PP  +        S+ + W+  
Sbjct: 684  RITVTAHTDVGPGPESLSVLIRTNED--------VPSGPPRKVEVEAVNSTSVKVSWRSP 735

Query: 957  -PDKIGGAEITGYYVNYREVIDGVP-GKWREANVKAVSEEAYKISNLKENMVYQFQVAAM 1014
             P+K  G +I GY V+Y  + +G P G+    +V     +   IS L+    Y   V A 
Sbjct: 736  VPNKQHG-QIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSYSLTVTAY 794

Query: 1015 NMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYF 1074
               G GA S      K    T AVPG P  L  +  + ++ ++QW PPV +   P+ GY 
Sbjct: 795  TTKGDGARSKP----KLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDT-FGPLQGY- 847

Query: 1075 VDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGK 1125
              LK  +   +    L E + K  +     + +G SYVFR+ A N+ G G+
Sbjct: 848  -RLKFGRKDMEPLTTL-EFSEKEDHFTATDIHKGASYVFRLSARNKVGFGE 896



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 98/454 (21%), Positives = 172/454 (37%), Gaps = 50/454 (11%)

Query: 689  ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPS 748
            ++P+      L D+ +  +Y     C   + +G      ++TV      +PK PG  + +
Sbjct: 281  DMPIGRNVLELNDVRQSANYT----CVAMSTLGVIEAIAQITVKA----LPKPPGTPVVT 332

Query: 749  RNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYI 808
             +T TS+ ++W+      E V YYI      + +      + V  +R++  GL     Y 
Sbjct: 333  ESTATSITLTWDSGNP--EPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYE 390

Query: 809  FRVRAVNAAG-----------LSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTAS 857
            FRV AVN  G            SE +  S   +V+A +    +  V     +EP G    
Sbjct: 391  FRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQG 450

Query: 858  RGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQ 917
              RV+    PT   +  +              N+  ++++ +   V ++       A   
Sbjct: 451  Y-RVYYTMDPTQHVNNWM------------KHNVADSQITTIGNLVPQKTYSVKVLAFTS 497

Query: 918  ---GKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYRE 974
               G   SD ++  T    P  P +         S++L W  P       I  Y + Y+ 
Sbjct: 498  IGDGPLSSD-IQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS---DTIANYELVYK- 552

Query: 975  VIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEW 1034
              DG  G+  E  +      +Y++  LK N +Y F++AA +  GLGA +A       +  
Sbjct: 553  --DGEHGE--EQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSK 608

Query: 1035 TIAVPGPPHSLKCSEVRKDSLVLQWK-PPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
              A   PP  + C+     S+++ W+ PPV      +T Y +       ++D+   +   
Sbjct: 609  PSA---PPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGI 665

Query: 1094 AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS 1127
                    +  L++   Y   V A    G G  S
Sbjct: 666  PSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPES 699



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 53/241 (21%), Positives = 94/241 (39%), Gaps = 27/241 (11%)

Query: 1389 IVWYKDEREISVD--EKHDFKDGICTLLITE--FSKKDAGIYEVILKDDRGKDKSRLKL- 1443
            IVW K  +++S    E  +F DG  ++L  +   + +D  IYE +  ++ G+     +L 
Sbjct: 55   IVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLT 114

Query: 1444 ------VDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGS 1497
                  +   F  + M    K+        +   A G      +T++ + L V+ S+N  
Sbjct: 115  VLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASG-NPDPEITWFKDFLPVDTSNNNG 173

Query: 1498 AIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAE 1557
             I+       G T  +  LQI +   +D+GKY                ++  +    Y+ 
Sbjct: 174  RIKQLRSESIGGTPIRGALQIEQSEESDQGKYEC--------------VATNSAGTRYSA 219

Query: 1558 FQRLKQAAIAEKNRARVLGGLPDV-VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD 1616
               L    + E  R      +P     I  G ++N+TC   G P P V W+   + L  +
Sbjct: 220  PANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPE 279

Query: 1617 D 1617
            D
Sbjct: 280  D 280



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 37/140 (26%), Positives = 53/140 (37%), Gaps = 15/140 (10%)

Query: 231 QQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWE 290
           Q EE+ + K   V       R S    L     Y  +L E   +  P F I P +H +  
Sbjct: 196 QSEESDQGKYECVATNSAGTRYSAPANL-----YVRELREVRRV-PPRFSIPPTNHEIMP 249

Query: 291 KENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQY 350
             +V + C   G P P V W      +           +   G + LE+N  D   +A Y
Sbjct: 250 GGSVNITCVAVGSPMPYVKWMLGAEDLTPED-------DMPIGRNVLELN--DVRQSANY 300

Query: 351 RASAMNVKGELSAYASVVVK 370
              AM+  G + A A + VK
Sbjct: 301 TCVAMSTLGVIEAIAQITVK 320



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 1037 AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIK 1096
            A+P PP +   +E    S+ L W     SG      Y++   + K  E+ ++ ++  A  
Sbjct: 321  ALPKPPGTPVVTESTATSITLTWD----SGNPEPVSYYIIQHKPKNSEELYKEIDGVATT 376

Query: 1097 NVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET 1137
                 V GL     Y FRV A+N  G G PS+   PV+ +T
Sbjct: 377  RY--SVAGLSPYSDYEFRVVAVNNIGRGPPSE---PVLTQT 412



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 10/128 (7%)

Query: 635 GIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNT-ELPVK 693
           G VPG P  L +     +  ++ W PP         Y   + + G ++ + + T E   K
Sbjct: 812 GAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQGY---RLKFGRKDMEPLTTLEFSEK 867

Query: 694 SPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKA-PGKIIPSRNTD 752
              F   D+ +G SY FR+   N  G GE      V  +    ++P   P  +     T 
Sbjct: 868 EDHFTATDIHKGASYVFRLSARNKVGFGEEM----VKEISIPEEVPTGFPQNLHSEGTTS 923

Query: 753 TSVVVSWE 760
           TSV +SW+
Sbjct: 924 TSVQLSWQ 931



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 1/68 (1%)

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST-ADSGKYG 1645
            G   +  C   GDP P++ W K  K +++     ++F+ G  +   I  + T  D   Y 
Sbjct: 38   GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97

Query: 1646 LVVKNKYG 1653
             V  N  G
Sbjct: 98   CVASNNVG 105


>gi|119220552 sidekick 1 [Homo sapiens]
          Length = 2213

 Score =  114 bits (284), Expect = 1e-24
 Identities = 177/692 (25%), Positives = 279/692 (40%), Gaps = 129/692 (18%)

Query: 507  EGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKF 566
            + AP  P+ +   E     + I W+ P    G  ILGY I        ++   + +P  F
Sbjct: 1375 DDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGI-ILGYQI--------AYRLASSSPHTF 1425

Query: 567  A---------RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRP 617
                      +F  T L    +YIFR+ A  + G G      EP+ A             
Sbjct: 1426 TTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWG------EPLEAT------------ 1467

Query: 618  SAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEA--TRSYVVLSWKPPGQRGHEGIMYFVEK 675
                   +I TE+       P PP +L V +A  T   + L W P G  G   I YF  +
Sbjct: 1468 -------VITTEKRER----PAPPRELLVPQAEVTARSLRLQWVP-GSDGASPIRYFTMQ 1515

Query: 676  C-EAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGD 734
              E     WQ  ++ +  ++    +  L    SY  R++ +N  G  + S  TE   V  
Sbjct: 1516 VRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEA--VTT 1573

Query: 735  KLDIP-KAPGKIIPSRNTDTSVVVSWEESKDAKELVG-------YYIEASV-AGSGKWEP 785
              D+P + PG +  + +T +SV++ W+  +D + L G       YY E    AGSG    
Sbjct: 1574 LQDVPGEPPGSVSATPHTTSSVLIQWQPPRD-ESLNGLLQGYRIYYRELEYEAGSGTEAK 1632

Query: 786  CNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQ------------------DSE 827
               NP+       H  +T QS    V + + + + E +                   +S 
Sbjct: 1633 TLKNPI-----ALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESP 1687

Query: 828  AIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVH-EASPPTFQKDALLGSKPNKPSLPS 886
            A        G  +P + P  + +   LTAS+  V  +  PP  Q   + G K       +
Sbjct: 1688 ASAPVEVFVGEAAPAMAPQ-NVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYY--WEA 1744

Query: 887  SSQNLGQTEVSKVSETVQ-----EELTPPPQ--------KAAPQGKSKSDPLKKKTDRAP 933
             SQN  +TE  KV    +     + LT   +         AA  G  KSDP + +T +A 
Sbjct: 1745 DSQN--ETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGP-KSDPQQGRTHQAA 1801

Query: 934  PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREV--IDGVPGKWREANVKAV 991
            P  P  +   E    ++ + W +P    G  + GY V Y  +  + GV  K     V+  
Sbjct: 1802 PGAPSFLAFSEITSTTLNVSWGEPAAANGI-LQGYRVVYEPLAPVQGV-SKVVTVEVRGN 1859

Query: 992  SEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVR 1051
             +   K+ +L + + Y F+V A  +       A       E      PG P  +  ++  
Sbjct: 1860 WQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAE----GSPGSPRDVLVTKSA 1915

Query: 1052 KDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV-------YLKVRG 1104
             + L LQW    HSG TP TGY +   EA+  ++   GL +  +K++        L +  
Sbjct: 1916 SE-LTLQWTEG-HSGDTPTTGYVI---EARPSDE---GLWDMFVKDIPRSATSYTLSLDK 1967

Query: 1105 LKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE 1136
            L++GV+Y FRV A+N+AG G+PS+ +  V A+
Sbjct: 1968 LRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQ 1999



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 211/963 (21%), Positives = 327/963 (33%), Gaps = 187/963 (19%)

Query: 276  APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYK-NQVPINVHANPGKYIIESRYGM 334
            AP F  +P   TV +     L C ++G P+P +TW + N +  +      ++++    G 
Sbjct: 479  APVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGG- 537

Query: 335  HTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKG-----------EFDETRFHA 383
              L+I     +D   Y   A N +G L+A A++ V                +      H 
Sbjct: 538  --LQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHC 595

Query: 384  GASTMPL----------SFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVV---- 429
            GA+  P           +  +TP    SR  +  D    +S    G+     C +V    
Sbjct: 596  GATHDPRVSLRYVWKKDNVALTPSS-TSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGG 654

Query: 430  ---------------------ITPEIKHFQPEI-QWYRNGVPLSPSKW--VQTLWSGERA 465
                                 ++P   H    +  W R     SP  +  V+   +    
Sbjct: 655  NDSRMARLEVIELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPW 714

Query: 466  TLTFSHLNKEDEGLYTIRVRMGEYYE------------QYSAYVFVRDADAEIEGAPAAP 513
             +  S++  E  G+    +     Y+            QYSA         E   AP  P
Sbjct: 715  KVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAP--P 772

Query: 514  LDVKCLEANKDYIIISWKQPAVDGGSPIL-GYFIDKCEVGTDS-WSQCNDTPVKFARFPV 571
             ++         I++ W+ P     + +L GY +     G    + Q N T  +     V
Sbjct: 773  KNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLV 832

Query: 572  TGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEE 631
            T LI    Y  +V A N  G+G  SR                                E 
Sbjct: 833  TDLIIWTQYEIQVAAYNGAGLGVFSRA-----------------------------VTEY 863

Query: 632  PSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELP 691
              +G+   PP ++       + +   W PP Q+   GI     K  A   +     T + 
Sbjct: 864  TLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGY-KLLAWPADAPEAVTVVT 922

Query: 692  VKSPRFA------LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKI 745
            + +P F       + +L +  +Y   V C  + G G PS    V    DK   P A G +
Sbjct: 923  I-APDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDK---PGAVGHL 978

Query: 746  IPSRNTDTSVVVSWEESKDAKELV-GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTG 804
              +   DTS+ VSW+E  +   ++ GY I   V G       +        +   GL + 
Sbjct: 979  SFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSL 1038

Query: 805  QSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEA 864
             +Y   V AV A G          +   + I  GV PD    L   P  L  S       
Sbjct: 1039 TTYTIDVAAVTAVGTG--------LVTSSTISSGVPPD----LPGAPSNLVISN-----I 1081

Query: 865  SPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSE-----TVQEELTPPPQKAAP--- 916
            SP    + A L  +P      S S+ + + +V  + +     T+ EE   P  +      
Sbjct: 1082 SP----RSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPN 1137

Query: 917  ----------------QGKSKSDPLKK--KTDRAPPS-PPCDITCLESFRDSMVLGWKQ- 956
                             G S   P  +  +T +APP   P  +T   +   S+ L W   
Sbjct: 1138 LTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPL 1197

Query: 957  PDKI--GGAEITGYYVNYREVIDGVPGKWRE-----ANVKAVS---EEAYKISNLKENMV 1006
            PD    G  E  GY + Y          WR      A  + VS   E  + I  L+E M 
Sbjct: 1198 PDSQYNGNPESVGYRIKY----------WRSDLQSSAVAQVVSDRLEREFTIEELEEWME 1247

Query: 1007 YQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVP-GPPHSLKCSEVRKDSLVLQW-KPPVH 1064
            Y+ Q+ A N  G G  S V      E    +VP   P ++    V    ++L W   P  
Sbjct: 1248 YELQMQAFNAVGAGPWSEVVRGRTRE----SVPSAAPENVSAEAVSSTQILLTWTSVPEQ 1303

Query: 1065 SGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVG 1124
                 + GY + L  AK  + + R             + GL++ V Y  +V A  + G G
Sbjct: 1304 DQNGLILGYKI-LFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNG 1362

Query: 1125 KPS 1127
             PS
Sbjct: 1363 VPS 1365



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 136/642 (21%), Positives = 247/642 (38%), Gaps = 83/642 (12%)

Query: 631  EPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTEL 690
            E ++   PGPP  L   E   + V + W+PP +     + Y +    A +        E+
Sbjct: 1371 ERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEV 1430

Query: 691  PVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKII--PS 748
                 +F   DLA   +Y FR+      G GEP EAT +T   +K + P  P +++   +
Sbjct: 1431 GATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITT--EKRERPAPPRELLVPQA 1488

Query: 749  RNTDTSVVVSWEESKDAKELVGYY-IEASVAGSGKWEPCNNN-PVKGSRFTCHGLVTGQS 806
              T  S+ + W    D    + Y+ ++      G+W+  +++   + +      L    S
Sbjct: 1489 EVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTS 1548

Query: 807  YIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVC--------------PALSDEPG 852
            Y  R++A N  G S++S ++EA+     + G     V               P   +   
Sbjct: 1549 YKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLN 1608

Query: 853  GLTAS-----RGRVHEASPPTFQK--------DALLGSKPNKPSLPSSSQNLGQTEVSKV 899
            GL        R   +EA   T  K         A L ++ +  ++ SSS +    E++ +
Sbjct: 1609 GLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTST-MCELTHL 1667

Query: 900  SETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGW-KQPD 958
             +  + E+         +  + +       + AP   P ++         + + W   P 
Sbjct: 1668 KKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPP 1727

Query: 959  KIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAG 1018
            +     I GY + Y E       +  +  V  + E   ++ NL  +  Y   ++A N AG
Sbjct: 1728 ESQNGNIQGYKIYYWEA--DSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAG 1785

Query: 1019 LGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLK 1078
             G  S   +    +    A PG P  L  SE+   +L + W  P  +    + GY V  +
Sbjct: 1786 DGPKSDPQQGRTHQ----AAPGAPSFLAFSEITSTTLNVSWGEPA-AANGILQGYRVVYE 1840

Query: 1079 EAKAKEDQWRGLNEAAIKNV------YLKVRGLKEGVSYVFRV--RAINQAGVGKPSDLA 1130
                 +    G+++     V      +LKVR L +GV+Y FRV  R I      + +  A
Sbjct: 1841 PLAPVQ----GVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITA 1896

Query: 1131 GPVVAETRPGT-KEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESK 1189
            GP  AE  PG+ ++V+V               K   +    W++ +     +    +E++
Sbjct: 1897 GP--AEGSPGSPRDVLVT--------------KSASELTLQWTEGHSGDTPTTGYVIEAR 1940

Query: 1190 GNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKR 1231
             +            D G++   V D    A+SY +  ++L++
Sbjct: 1941 PS------------DEGLWDMFVKDIPRSATSYTLSLDKLRQ 1970



 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 119/531 (22%), Positives = 202/531 (38%), Gaps = 50/531 (9%)

Query: 620  PWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAG 679
            P T Q++ T+E+      PG    LS TE   + + +SW+ P ++      Y +   E  
Sbjct: 959  PSTPQLVWTQEDK-----PGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQIS-WEVY 1012

Query: 680  TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 739
              N  R+   L   +  + +  L+   +Y   V    + G G  + +T  +  G   D+P
Sbjct: 1013 GRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISS--GVPPDLP 1070

Query: 740  KAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYI-EASVAGSGKWEPC-----NNNPVKG 793
             AP  ++ S  +  S  + +    D K  +  +I E  V   G  E         N    
Sbjct: 1071 GAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDA 1130

Query: 794  SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGG 853
                   L     Y FR++ VN  G S YS  S  I+   A      PDV P        
Sbjct: 1131 QMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQA-----PPDVAPTSVTVR-- 1183

Query: 854  LTASRGRVHEASPPTFQKDALLGSKPN---------KPSLPSS------SQNLGQT-EVS 897
             TAS   +     P    D+     P          +  L SS      S  L +   + 
Sbjct: 1184 -TASETSLRLRWVPL--PDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIE 1240

Query: 898  KVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQ- 956
            ++ E ++ EL      A   G        +  +  P + P +++        ++L W   
Sbjct: 1241 ELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSV 1300

Query: 957  PDKIGGAEITGYYVNYR-EVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMN 1015
            P++     I GY + +R + +D  P   R   V+    ++  ++ L++ ++Y+ QV A  
Sbjct: 1301 PEQDQNGLILGYKILFRAKDLDPEP---RSHIVRGNHTQSALLAGLRKFVLYELQVLAFT 1357

Query: 1016 MAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFV 1075
              G G PS      + ++     PGPP  L   EVR  S+ + W+PP       + GY +
Sbjct: 1358 RIGNGVPSTPLILERTKD---DAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGI-ILGYQI 1413

Query: 1076 DLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKP 1126
              + A +    +  +   A    +     L    +Y+FR+ A  + G G+P
Sbjct: 1414 AYRLASSSPHTFTTVEVGATVRQF-TATDLAPESAYIFRLSAKTRQGWGEP 1463



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 70/306 (22%), Positives = 119/306 (38%), Gaps = 32/306 (10%)

Query: 930  DRAPPSPPCDITCLESFRDSMVLGWKQPDKIG-GAEITGYYVNYREVIDGVPGKWREANV 988
            +  P +PP +I        S+++ W+ P +      + GY + YR  + G+PG++++ N+
Sbjct: 765  EEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYR--LAGLPGEYQQRNI 822

Query: 989  KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTI-AVP-GPPHSLK 1046
             +       +++L     Y+ QVAA N AGLG  S         E+T+  VP  PP +++
Sbjct: 823  TSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRA-----VTEYTLQGVPTAPPQNVQ 877

Query: 1047 CSEVRKDSLVLQWKPPVHSGRTPVT-GYFVDLKEAKAKE--------DQWRGLNEAAIKN 1097
               V   ++   W PP       +  GY +    A A E          + G++   I N
Sbjct: 878  TEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITN 937

Query: 1098 VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGT---KEVVVNVDDDGVI 1154
                   LK+  +Y   V      G G PS        E +PG          +D    +
Sbjct: 938  -------LKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKV 990

Query: 1155 SLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTD 1214
            S     +K    + +  S +     DS    +    N T   +K  G+  L  Y+ DV  
Sbjct: 991  SWQEPLEKNGIITGYQISWEVYGRNDS---RLTHTLNSTTHEYKIQGLSSLTTYTIDVAA 1047

Query: 1215 TDGIAS 1220
               + +
Sbjct: 1048 VTAVGT 1053



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 62/240 (25%), Positives = 95/240 (39%), Gaps = 42/240 (17%)

Query: 507  EGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKF 566
            + AP AP  +   E     + +SW +PA   G  + GY +    +           PV+ 
Sbjct: 1799 QAAPGAPSFLAFSEITSTTLNVSWGEPAAANGI-LQGYRVVYEPL----------APVQG 1847

Query: 567  ARFPVTGLIEGR-SYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQI 625
                VT  + G      +VR + K G+ +  RV        P  +A + +          
Sbjct: 1848 VSKVVTVEVRGNWQRWLKVRDLTK-GVTYFFRVQARTITYGPELQANITA---------- 1896

Query: 626  IVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEG----IMYFVEKCEAGTE 681
                  P+EG  PG P D+ VT++  S + L W      GH G      Y +E   +   
Sbjct: 1897 -----GPAEG-SPGSPRDVLVTKSA-SELTLQW----TEGHSGDTPTTGYVIEARPSDEG 1945

Query: 682  NWQRVNTELP--VKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 739
             W     ++P    S   +L  L +G +Y FRV   N AG GEPS  +  T V  +++ P
Sbjct: 1946 LWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPS--TAVSAQVEAP 2003



 Score = 39.7 bits (91), Expect = 0.025
 Identities = 54/256 (21%), Positives = 95/256 (37%), Gaps = 35/256 (13%)

Query: 1391 WYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKE 1450
            W +D+ E++     ++K      +I    K DAG Y  ++++  G    R   V  A+  
Sbjct: 138  WMRDDSELTTYSS-EYK-----YIIPSLQKLDAGFYRCVVRNRMGALLQRKSEVQVAYMG 191

Query: 1451 LMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVT 1510
              M+  ++  +S      Q  A  + L    +Y     +V W   G  I  S+R+   + 
Sbjct: 192  SFMDTDQRKTVS------QGRAAILNLLPITSY--PRPQVTWFREGHKIIPSNRIAITLE 243

Query: 1511 GEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKN 1570
             +   L I   T +D G Y ++  + K G  KT      +        + +    +    
Sbjct: 244  NQ---LVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPG 300

Query: 1571 RARVLGGLPDVVTIQEGKALNLTCNVWGDPPPE--VSWLKNEKALASDDHCNLKFEAGRT 1628
               V+ G  +           L C     P  +  V+W +N   + S  H       GR 
Sbjct: 301  NRSVVAGSSET---------TLECIASARPVEDLSVTWKRNGVRITSGLH-----SFGRR 346

Query: 1629 AYFTINGVSTADSGKY 1644
               TI+  ++AD+G Y
Sbjct: 347  --LTISNPTSADTGPY 360



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 5/93 (5%)

Query: 273 LLHAPEFIIKPRSHTVWE-KENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESR 331
           ++  P F  +P S    E +E V + C   G P P + WYK+ + I+   NP +Y + + 
Sbjct: 382 IIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNP-RYKVLAS 440

Query: 332 YGMHTLEINGCDFEDTAQYRASAMNVKGELSAY 364
            G+   ++     ED+  ++  A N  GE+  +
Sbjct: 441 GGLRIQKLRP---EDSGIFQCFASNEGGEIQTH 470



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 27/95 (28%), Positives = 39/95 (41%)

Query: 1570 NRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTA 1629
            N A V    P   T+ +G    L C V G P P ++W +    LAS      +F    + 
Sbjct: 477  NIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESG 536

Query: 1630 YFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVF 1664
               I  V   D+G Y     N  GS  +  T++V+
Sbjct: 537  GLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVW 571



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 40/171 (23%), Positives = 66/171 (38%), Gaps = 29/171 (16%)

Query: 1485 VEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTV 1544
            VEDL V W  NG       R+ +G+      L I+ PT  D G YV E            
Sbjct: 322  VEDLSVTWKRNGV------RITSGLHSFGRRLTISNPTSADTGPYVCE-----------A 364

Query: 1545 DLSGQAYDEAYAE--FQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPP 1602
             L G A++ A A      ++      +  +R+   + + V        ++ C   G P P
Sbjct: 365  ALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETV--------DIGCQAMGVPLP 416

Query: 1603 EVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYG 1653
             + W K+  A++     N +++   +    I  +   DSG +     N+ G
Sbjct: 417  TLQWYKD--AISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFASNEGG 465



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 11/78 (14%)

Query: 1577 GLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGV 1636
            GLP +    EG  L LTC   G  P E  W++++  L +               + I  +
Sbjct: 111  GLPQIHL--EGNRLVLTCLAEGSWPLEFKWMRDDSELTT---------YSSEYKYIIPSL 159

Query: 1637 STADSGKYGLVVKNKYGS 1654
               D+G Y  VV+N+ G+
Sbjct: 160  QKLDAGFYRCVVRNRMGA 177


>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
            precursor [Homo sapiens]
          Length = 1907

 Score =  113 bits (283), Expect = 1e-24
 Identities = 189/880 (21%), Positives = 326/880 (37%), Gaps = 143/880 (16%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P   + P+   V +     + C+  G P+P ++W+K+ +P++   + G+ I + R G   
Sbjct: 135  PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGR-IKQLRSG--A 191

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTP 396
            L+I   +  D  +Y   A N  G                   TR+ A     P +  V  
Sbjct: 192  LQIESSEESDQGKYECVATNSAG-------------------TRYSA-----PANLYVRV 227

Query: 397  YGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWV 456
               A RF I    +  +     G +++L C  V  P      P ++W      L+    +
Sbjct: 228  RRVAPRFSIPPSSQEVMP----GGSVNLTCVAVGAP-----MPYVKWMMGAEELTKEDEM 278

Query: 457  QTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEI--EGAPAAPL 514
                   R  L  S++           VR   Y     + + + +A A++  +  P  P+
Sbjct: 279  PV----GRNVLELSNV-----------VRSANYTCVAISSLGMIEATAQVTVKALPKPPI 323

Query: 515  DVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGL 574
            D+   E     + ++W         P+  Y I     GT+   Q  D  V   R+ + GL
Sbjct: 324  DLVVTETTATSVTLTWDS---GNSEPVTYYGIQYRAAGTEGPFQEVDG-VATTRYSIGGL 379

Query: 575  IEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSE 634
                 Y FRV AVN +G G PS           A +AR         TG     E+ PS 
Sbjct: 380  SPFSEYAFRVLAVNSIGRGPPSE----------AVRAR---------TG-----EQAPS- 414

Query: 635  GIVPGPPTDLSVTEATRSYVVLSWKPPGQ-----RGHEGIMYFVEKCEAGTENWQRVNTE 689
                 PP  +     + S +++ W+PP +     RG+   +Y+          W + NT+
Sbjct: 415  ----SPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYR--VYYTPDSRRPPNAWHKHNTD 468

Query: 690  LPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSR 749
              + +    +  L  G +Y  RV    + G G PS   +V     +  +P  P       
Sbjct: 469  AGLLT---TVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKT---QQGVPAQPADFQAEV 522

Query: 750  NTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIF 809
             +DT + +SW      + ++   +  +     +      +P   S +T   L     Y F
Sbjct: 523  ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT--SSYTLEDLKPDTLYRF 580

Query: 810  RVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTF 869
            ++ A +  G+  ++   EA   ++         +C ++    G  T    RV    PP  
Sbjct: 581  QLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSM----GSTTV---RVSWVPPPAD 633

Query: 870  QKDALL-----------GSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQG 918
             ++ ++           G    +  +   S+     ++  + +  +  +          G
Sbjct: 634  SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 693

Query: 919  KSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWK--QPDKIGGAEITGYYVNYREVI 976
               S  L +  +  P  PP  +        ++ + WK   P K  G +I GY V Y  + 
Sbjct: 694  PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHG-QIRGYQVTYVRLE 752

Query: 977  DGVPG--------KWREANVKAVSEEAYK--ISNLKENMVYQFQVAAMNMAGLGAPSAVS 1026
            +G P            EA  +    E Y+  IS L     Y   VAA    G GA S   
Sbjct: 753  NGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKP- 811

Query: 1027 ECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQ 1086
               K    T AVPG P ++  S    ++ +LQW PP       + G  +  +    + D+
Sbjct: 812  ---KIVTTTGAVPGRP-TMMISTTAMNTALLQWHPP-----KELPGELLGYRLQYCRADE 862

Query: 1087 WR-GLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGK 1125
             R    +    + +  V GL +G +Y+FR+ A N+AG+G+
Sbjct: 863  ARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGE 902



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 74/284 (26%), Positives = 115/284 (40%), Gaps = 27/284 (9%)

Query: 929  TDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988
            T +A P PP D+   E+   S+ L W   D      +T Y + YR    G  G ++E  V
Sbjct: 314  TVKALPKPPIDLVVTETTATSVTLTW---DSGNSEPVTYYGIQYRAA--GTEGPFQE--V 366

Query: 989  KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCS 1048
              V+   Y I  L     Y F+V A+N  G G PS   E  +      A   PP  ++  
Sbjct: 367  DGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPS---EAVRARTGEQAPSSPPRRVQAR 423

Query: 1049 EVRKDSLVLQWKPPVHSGRTPVTGYFVDLK-EAKAKEDQWRGLNEAAIKNVYLKVRGLKE 1107
             +   ++++QW+PP       V GY V    +++   + W   N  A   +   V  L  
Sbjct: 424  MLSASTMLVQWEPPEEPNGL-VRGYRVYYTPDSRRPPNAWHKHNTDA--GLLTTVGSLLP 480

Query: 1108 GVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGT----KEVVVNVDDDGVISLNFECDKM 1163
            G++Y  RV A    G G PS     +  +T+ G      +    V+ D  I L++    +
Sbjct: 481  GITYSLRVLAFTAVGDGPPSP---TIQVKTQQGVPAQPADFQAEVESDTRIQLSW----L 533

Query: 1164 TPKSE--FSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDL 1205
             P  E    +   Y + ED  +    +    +  T +DL  D L
Sbjct: 534  LPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTL 577



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 187/905 (20%), Positives = 310/905 (34%), Gaps = 194/905 (21%)

Query: 276  APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
            AP F I P S  V    +V L C   G P P V W      +           E   G +
Sbjct: 231  APRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED-------EMPVGRN 283

Query: 336  TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRY-KGEFDETRFHAGASTMPLSFG- 393
             LE++  +   +A Y   A++  G + A A V VK   K   D       A+++ L++  
Sbjct: 284  VLELS--NVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDS 341

Query: 394  -----VTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGV 448
                 VT YG   R           + G EG    +         I    P  ++    +
Sbjct: 342  GNSEPVTYYGIQYR-----------AAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVL 390

Query: 449  PLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEG 508
                   V ++  G  +                +R R GE                +   
Sbjct: 391  A------VNSIGRGPPSE--------------AVRARTGE----------------QAPS 414

Query: 509  APAAPLDVKCLEANKDYIIISWKQPAVDGGSPILG---YFIDKCEVGTDSWSQCNDTPVK 565
            +P   +  + L A+   +++ W+ P    G  + G   Y+        ++W + N     
Sbjct: 415  SPPRRVQARMLSAST--MLVQWEPPEEPNGL-VRGYRVYYTPDSRRPPNAWHKHNTDAGL 471

Query: 566  FARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQI 625
                 V  L+ G +Y  RV A   +G G             P+   ++K++   P     
Sbjct: 472  LT--TVGSLLPGITYSLRVLAFTAVGDG------------PPSPTIQVKTQQGVP----- 512

Query: 626  IVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQR 685
                           P D      + + + LSW  P Q     IMY +    A  E+ Q 
Sbjct: 513  -------------AQPADFQAEVESDTRIQLSWLLPPQ--ERIIMYELVYWAAEDEDQQH 557

Query: 686  VNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKI 745
              T  P  S  + L DL     Y F++   +  GVG  +   E          P  P K+
Sbjct: 558  KVTFDPTSS--YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAP--PQKV 613

Query: 746  IPSRNTDTSVVVSW--EESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVT 803
            +      T+V VSW    +     ++  Y  A  A  G+            R    G+  
Sbjct: 614  MCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGE---------DRGRHVVDGISR 664

Query: 804  GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPAL----SDEPGG------ 853
              S      + +  GL ++++    + V+A    G  P+  P L     D P G      
Sbjct: 665  EHS------SWDLVGLEKWTE--YRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVE 716

Query: 854  ---LTASRGRVHEASP-PTFQKDALLGSKPNKPSLPSS-------------SQNLGQTEV 896
               L ++   V+   P P+ Q   + G +     L +              ++   + E 
Sbjct: 717  VEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEE 776

Query: 897  SKVSETVQEELTPPPQKAAPQGK-------SKSDPLKKKTDRAPPSPPCDITCLESFRDS 949
            S+  ET    LTP    +            ++S P    T  A P  P  +    +  ++
Sbjct: 777  SEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAM-NT 835

Query: 950  MVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQF 1009
             +L W  P ++ G E+ GY + Y    +  P            ++ + ++ L +   Y F
Sbjct: 836  ALLQWHPPKELPG-ELLGYRLQYCRADEARPNTIDFGK----DDQHFTVTGLHKGTTYIF 890

Query: 1010 QVAAMNMAGLGAPSAVSECFKCEEWTIAVP-----GPPHSLKCSEVRKDSLVLQWKPPVH 1064
            ++AA N AGLG      E F+ E   I  P     G P +L  + +   +  L W PPV 
Sbjct: 891  RLAAKNRAGLG------EEFEKE---IRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVL 941

Query: 1065 SGRT-PVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVR----GLKEGVSYVFRVRAIN 1119
            + R   +  Y V  ++  ++++         ++N+    R    GLK   +Y  +VRA  
Sbjct: 942  AERNGRIISYTVVFRDINSQQE---------LQNITTDTRFTLTGLKPDTTYDIKVRAWT 992

Query: 1120 QAGVG 1124
              G G
Sbjct: 993  SKGSG 997



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 66/254 (25%), Positives = 99/254 (38%), Gaps = 51/254 (20%)

Query: 527  IISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFAR----FPVTGLIEGRSYIF 582
            ++ W  P    G  +LGY +  C        +     + F +    F VTGL +G +YIF
Sbjct: 837  LLQWHPPKELPGE-LLGYRLQYCRA-----DEARPNTIDFGKDDQHFTVTGLHKGTTYIF 890

Query: 583  RVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPT 642
            R+ A N+ G+G            +  EK             +I   E+ PS     G P 
Sbjct: 891  RLAAKNRAGLG------------EEFEK-------------EIRTPEDLPS-----GFPQ 920

Query: 643  DLSVTEATRSYVVLSWKPP--GQRGHEGIMYFVEKCEAGT-ENWQRVNTELPVKSPRFAL 699
            +L VT  T S   L+W PP   +R    I Y V   +  + +  Q + T+      RF L
Sbjct: 921  NLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITTD-----TRFTL 975

Query: 700  FDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSW 759
              L    +Y  +VR   S G G  S + +   +  +    K       +    TSV++SW
Sbjct: 976  TGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAK---NFRVAAAMKTSVLLSW 1032

Query: 760  EESKDAKELVGYYI 773
            E     K  V + I
Sbjct: 1033 EVPDSYKSAVPFKI 1046



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
            P +  +++ +   + C   G+P PE+SW K+   +      N + +  R+    I     
Sbjct: 141  PQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPV-DPATSNGRIKQLRSGALQIESSEE 199

Query: 1639 ADSGKYGLVVKNKYGSETS 1657
            +D GKY  V  N  G+  S
Sbjct: 200  SDQGKYECVATNSAGTRYS 218



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 26/109 (23%), Positives = 44/109 (40%), Gaps = 3/109 (2%)

Query: 1578 LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
            +P+  T   G   +  C   G+P P ++W+K  K ++S     ++F+ G  +   I  + 
Sbjct: 38   VPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLR 97

Query: 1638 T-ADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGKKAK 1685
               D   Y     N  G   +   +SV   EEE       S+  G + K
Sbjct: 98   VQRDEAIYECTATNSLGEINTSAKLSVL--EEEQLPPGFPSIDMGPQLK 144



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 55/263 (20%), Positives = 101/263 (38%), Gaps = 42/263 (15%)

Query: 1389 IVWYKDEREISVD--EKHDFKDGICTLLITEFSK--KDAGIYEVILKDDRGKDKSRLKL- 1443
            I W K  +++S    E  +F DG  ++L  +  +  +D  IYE    +  G+  +  KL 
Sbjct: 64   ITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLS 123

Query: 1444 ------VDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGS 1497
                  +   F  + M    K+   A    +   A G      ++++ + L V+ + +  
Sbjct: 124  VLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGG-NPDPEISWFKDFLPVDPATSNG 182

Query: 1498 AIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAE 1557
             I+   ++++G       LQI     +D+GKY               + +G  Y      
Sbjct: 183  RIK---QLRSGA------LQIESSEESDQGKYECV----------ATNSAGTRYSAPANL 223

Query: 1558 FQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDD 1617
            + R+++ A             P    +  G ++NLTC   G P P V W+   + L  +D
Sbjct: 224  YVRVRRVAPR-------FSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED 276

Query: 1618 HCNLKFEAGRTAYFTINGVSTAD 1640
                +   GR      N V +A+
Sbjct: 277  ----EMPVGRNVLELSNVVRSAN 295


>gi|222352127 sidekick 2 [Homo sapiens]
          Length = 2172

 Score =  110 bits (275), Expect = 1e-23
 Identities = 159/656 (24%), Positives = 251/656 (38%), Gaps = 93/656 (14%)

Query: 507  EGAPAA-PLDVKCLEANKDYIIISWKQ-PAVDGGSPILGYFIDKCEVGTDSWSQCNDTPV 564
            E  P++ P +V  L      +++ W + P  D    +LGY +   E  +D+  +      
Sbjct: 1196 ESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEG 1255

Query: 565  KFARFP-VTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTG 623
              +R   +TGL +   Y  +V A  ++G G PS        LD                 
Sbjct: 1256 NSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDD---------------- 1299

Query: 624  QIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFV-EKCEAGTEN 682
                         VPGPP  +   E   + V L W+PP       + Y +  +    T N
Sbjct: 1300 -------------VPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN 1346

Query: 683  WQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAP 742
               V    P  + ++    L     Y FR+      G GE +EA  VT   +K D P+ P
Sbjct: 1347 TATVEVLAP-SARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTT--EKRDRPQPP 1403

Query: 743  GKIIPSRNT--DTSVVVSWEESKDAKELVGYY-IEASVAGSGKWEPCNNNPV-KGSRFTC 798
             + +  +      SV++SWE   D    V YY I+     SG+W   + +     S F  
Sbjct: 1404 SRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIV 1463

Query: 799  HGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASR 858
              L    SY FRV+A N  G SE+S++SE++    A     +PD  P +       T S 
Sbjct: 1464 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQA-----APDEAPTILSVTPHTTTS- 1517

Query: 859  GRVHEASPPTFQK--DALLGSK------------------PNKPSLP------------S 886
              +    PP   K    LLG +                   N P                
Sbjct: 1518 -VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL 1576

Query: 887  SSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESF 946
            S  +L Q E+  +++  + E+      A  +G S         +  P + P ++    + 
Sbjct: 1577 SRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGAT 1636

Query: 947  RDSMVLGWKQP--DKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKEN 1004
               + + W+ P  D   G +I GY + + E   G            ++E + K+ NL   
Sbjct: 1637 ATQLDVTWEPPPLDSQNG-DIQGYKIYFWEAQRG--NLTERVKTLFLAENSVKLKNLTGY 1693

Query: 1005 MVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVH 1064
              Y   VAA N AG G  S  ++     +   A P  P S+K SE+   S+ + W+ P  
Sbjct: 1694 TAYMVSVAAFNAAGDGPRSTPTQ----GQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQF 1749

Query: 1065 SGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN---VYLKVRGLKEGVSYVFRVRA 1117
                 + GY + + E  +  D    +    +K    ++LKV+ L EGV+Y FR+RA
Sbjct: 1750 PNGI-LEGYRL-VYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA 1803



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 194/902 (21%), Positives = 332/902 (36%), Gaps = 146/902 (16%)

Query: 276  APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
            AP     P   TV +  +V L C  +G P P +TW K +  +   +           G  
Sbjct: 401  APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESG-- 458

Query: 336  TLEINGCDFEDTAQYRASAMNVKGELSAYASVVV----KRYKGEFDETRFHAGASTMPLS 391
            +L I+     D   Y   A N +G   A A +VV    +  K   D++      ++M   
Sbjct: 459  SLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVC- 517

Query: 392  FGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLS 451
             GVT            D +  + +  E +  +LG             P I+  RNG    
Sbjct: 518  -GVT-----------HDPRVTIRYIWEKDGATLGTES---------HPRIRLDRNG---- 552

Query: 452  PSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPA 511
             S  +   WSG             D G YT RV      +  SA++ VR    ++  AP 
Sbjct: 553  -SLHISQTWSG-------------DIGTYTCRVISAGGNDSRSAHLRVR----QLPHAPE 594

Query: 512  APLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPV 571
             P+        +  I ++W +P  DG SP++ Y ++  E              K     V
Sbjct: 595  HPV-ATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTV 652

Query: 572  TGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEE 631
             GL+  RSY FR+ AVN +G G  S+ +E V+                       + EE 
Sbjct: 653  KGLVPARSYQFRLCAVNDVGKGQFSKDTERVS-----------------------LPEEP 689

Query: 632  PSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM--YFVEKCEAGTENWQRVNTE 689
            P+      PP ++  +  T   +++ W+PP +    GI+  Y +  C AG     +    
Sbjct: 690  PT-----APPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI 744

Query: 690  LPVKSPRFALFDLAEGKSYCFRVRCSNSAGVG-EPSEATEVTVVGDKLDIPKA-PGKIIP 747
                     L DL    +Y   V   NSAG+G   S+ TE T+ G    +P   PG +  
Sbjct: 745  TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQG----VPTVPPGNVHA 800

Query: 748  SRNTDTSVVVSWEESKDAKELV-----GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLV 802
                 T++  +W  +  + + +     GY + A       WEP     V         +V
Sbjct: 801  EATNSTTIRFTW--NAPSPQFINGINQGYKLIA-------WEPEQEEEVT--------MV 843

Query: 803  TGQ-SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGG--VSPDVCPALSDEPGGL-TASR 858
            T + ++   +     +GL ++++   ++      G G   +P +     D PG +   S 
Sbjct: 844  TARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSF 903

Query: 859  GRVHEAS------PPTFQKDALLG-----SKPNKPS------LPSSSQNLGQTEVSKVSE 901
              + + S       P  +   L G      + N+ +      LP+ +     T ++ ++ 
Sbjct: 904  SEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALT- 962

Query: 902  TVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIG 961
            T   E+     K   QG+  +  +        P PP ++        S+ L ++ P   G
Sbjct: 963  TYTIEVAAMTSKG--QGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR-PGYDG 1019

Query: 962  GAEITGYYVNYREVIDGVPGKWREANVKAVSEEA--YKISNLKENMVYQFQVAAMNMAGL 1019
               I+ + V  +  + G   +W   +  +   +A   ++ +L     Y F++  +N+ G 
Sbjct: 1020 KTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGT 1079

Query: 1020 GAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKP---PVHSGRTPVTGYFVD 1076
              PS  S   K +         P ++      + SL L+W P     ++G     GY + 
Sbjct: 1080 SPPSQPSR--KIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIK 1137

Query: 1077 LKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE 1136
               +         + +  ++  Y  +  L+E   Y  +V+A N  G G  S     VV  
Sbjct: 1138 YSRSDGHGKTLSHVVQDRVERDY-TIEDLEEWTEYRVQVQAFNAIGSGPWSQ---TVVGR 1193

Query: 1137 TR 1138
            TR
Sbjct: 1194 TR 1195



 Score = 90.9 bits (224), Expect = 9e-18
 Identities = 153/680 (22%), Positives = 262/680 (38%), Gaps = 104/680 (15%)

Query: 506  IEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVK 565
            ++  P  P+ +   E     + + W+ PA   G  +      +    T + +        
Sbjct: 1297 LDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPS 1356

Query: 566  FARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQI 625
              ++  TGL     Y+FR+ A  + G G            + AE               +
Sbjct: 1357 ARQYTATGLKPESVYLFRITAQTRKGWG------------EAAEA--------------L 1390

Query: 626  IVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYF-VEKCEAGTENWQ 684
            +VT E+      P  P         RS V+LSW+P G  G   + Y+ ++  E  +  W 
Sbjct: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARS-VLLSWEP-GSDGLSPVRYYTIQTRELPSGRWA 1448

Query: 685  RVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATE-VTVVGDKLDIPKAPG 743
              +  +   +  F +  L    SY FRV+ +N  G  E SE +E +T +    D  +AP 
Sbjct: 1449 LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPD--EAPT 1506

Query: 744  KIIPSRNTDTSVVVSWE---ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHG 800
             +  + +T TSV++ W+   E K    L+G+ I        ++       ++G  FT  G
Sbjct: 1507 ILSVTPHTTTSVLIRWQPPAEDKINGILLGFRI--------RYRELLYEGLRG--FTLRG 1556

Query: 801  LVT-GQSY-----IFRVRAVNAAGLSEYSQDSE--------AIEVKAAIGGGVS------ 840
            +   G ++     ++ +R ++   L++Y  D+          + V  A+G G S      
Sbjct: 1557 INNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEV 1616

Query: 841  ------PDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSK-----PNKPSLPSSSQ 889
                  P   P      G          E  P   Q   + G K       + +L    +
Sbjct: 1617 FVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVK 1676

Query: 890  NL----GQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLES 945
             L       ++  ++      ++     AA  G  +S P + +T +A PS P  +   E 
Sbjct: 1677 TLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP-RSTPTQGQTQQAAPSAPSSVKFSEL 1735

Query: 946  FRDSMVLGWKQPDKIGGAEITGYYVNYREV--IDGVPGKWREANVKAVSEEAYKISNLKE 1003
               S+ + W+ P    G  + GY + Y     +DGV  K    +VK  S    K+ +L E
Sbjct: 1736 TTTSVNVSWEAPQFPNGI-LEGYRLVYEPCSPVDGV-SKIVTVDVKGNSPLWLKVKDLAE 1793

Query: 1004 NMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPV 1063
             + Y+F++ A      G     +      E     PG P  ++ S     ++ + W    
Sbjct: 1794 GVTYRFRIRAKTFT-YGPEIEANVTTGPGEGAPGPPGVPIIVRYSS----AIAIHWSSG- 1847

Query: 1064 HSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRG-------LKEGVSYVFRVR 1116
              G+ P+T Y +   EA+  ++   GL +  IK++  +V         LK GVSY FRV 
Sbjct: 1848 DPGKGPITRYVI---EARPSDE---GLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVI 1901

Query: 1117 AINQAGVGKPSDLAGPVVAE 1136
            A+N  G G PS  +  V A+
Sbjct: 1902 AVNDYGFGTPSSPSQSVPAQ 1921



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 145/624 (23%), Positives = 233/624 (37%), Gaps = 82/624 (13%)

Query: 528  ISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAV 587
            +SW++P    G  + GY I   E    +    +  P     + VTGL    +Y   V A+
Sbjct: 913  VSWQEPGEKNGI-LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAM 971

Query: 588  NKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVT 647
               G G  S  +                           ++   P E  +PGPPT+L ++
Sbjct: 972  TSKGQGQVSAST---------------------------ISSGVPPE--LPGPPTNLGIS 1002

Query: 648  EATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGT----ENW---QRVNTELPVKSPRFALF 700
                  V L ++P G  G   I  ++ + + G     E W    +++ E   +S      
Sbjct: 1003 NIGPRSVTLQFRP-GYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVP-- 1059

Query: 701  DLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSR-----NTDTSV 755
            DL     Y FR+R  N  G   PS+ +       K+   +AP  + P+       ++TS+
Sbjct: 1060 DLNPFTCYSFRMRQVNIVGTSPPSQPSR------KIQTLQAPPDMAPANVSLRTASETSL 1113

Query: 756  VVSWE-----ESKDAKELVGYYIEASVA-GSGKWEPCNNNPVKGSRFTCHGLVTGQSYIF 809
             + W      E     E VGY I+ S + G GK             +T   L     Y  
Sbjct: 1114 WLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRV 1173

Query: 810  RVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTF 869
            +V+A NA G   +SQ       ++    G  P    AL+     +      V EA     
Sbjct: 1174 QVQAFNAIGSGPWSQTVVGRTRESVPSSG--PTNVSALATTSSSMLVRWSEVPEAD---- 1227

Query: 870  QKDALLGSKPNKPSLPSSSQ---------NLGQTEVSKVSETVQEELTPPPQKAAPQGKS 920
            +   +LG K       S +Q         +    +++ + + V  E+          G  
Sbjct: 1228 RNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1287

Query: 921  KSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP 980
               P+ ++T    P PP  I   E    S+ L W+ P    G  I  Y + +R  ++   
Sbjct: 1288 SHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHR--LNTTT 1344

Query: 981  GKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG 1040
                   V A S   Y  + LK   VY F++ A    G G  +A +     E+     P 
Sbjct: 1345 ANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGE-AAEALVVTTEKRDRPQPP 1403

Query: 1041 PPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYL 1100
                ++  +VR  S++L W+P    G +PV  Y +  +E  +   +W  L+ A++ +   
Sbjct: 1404 SRPMVQQEDVRARSVLLSWEPG-SDGLSPVRYYTIQTRELPS--GRW-ALHSASVSHNAS 1459

Query: 1101 K--VRGLKEGVSYVFRVRAINQAG 1122
               V  LK   SY FRV+A N  G
Sbjct: 1460 SFIVDRLKPFTSYKFRVKATNDIG 1483



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 133/618 (21%), Positives = 220/618 (35%), Gaps = 91/618 (14%)

Query: 468  TFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYII 527
            T + L  E   L+ I  +  + + + +  + V     +    P+ P+ V+  +     ++
Sbjct: 1361 TATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM-VQQEDVRARSVL 1419

Query: 528  ISWKQPAVDGGSPILGYFIDKCEVGTDSWS-QCNDTPVKFARFPVTGLIEGRSYIFRVRA 586
            +SW +P  DG SP+  Y I   E+ +  W+          + F V  L    SY FRV+A
Sbjct: 1420 LSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKA 1478

Query: 587  VNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSV 646
             N +G    S  SE +  L  A                       P E      PT LSV
Sbjct: 1479 TNDIGDSEFSEESESLTTLQAA-----------------------PDEA-----PTILSV 1510

Query: 647  TEATRSYVVLSWKPPGQRGHEGIM-----------------YFVEKCEAGTENWQRVNTE 689
            T  T + V++ W+PP +    GI+                 + +         W  + + 
Sbjct: 1511 TPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSM 1570

Query: 690  LPVKS------PRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPG 743
              +++       ++ L +L + + Y  R+   N+ G G PS   +   VG+ +    AP 
Sbjct: 1571 YSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAVP-TAAPR 1628

Query: 744  KIIPSRNTDTSVVVSWEE---SKDAKELVGYYIEASVAGSGK-WEPCNNNPVKGSRFTCH 799
             ++    T T + V+WE         ++ GY I    A  G   E      +  +     
Sbjct: 1629 NVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLK 1688

Query: 800  GLVTGQSYIFRVRAVNAA----------GLSEYSQDSEAIEVKAAIGGGVSPDVCPALSD 849
             L    +Y+  V A NAA          G ++ +  S    VK +     S +V      
Sbjct: 1689 NLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQ 1748

Query: 850  EPGGLTASRGRVHEASPPT--FQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEEL 907
             P G+      V+E   P     K   +  K N P            +V  ++E V    
Sbjct: 1749 FPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPL---------WLKVKDLAEGVTYRF 1799

Query: 908  TPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG 967
                 K    G      +        P PP  +  +  +  ++ + W   D  G   IT 
Sbjct: 1800 R-IRAKTFTYGPEIEANVTTGPGEGAPGPP-GVPIIVRYSSAIAIHWSSGDP-GKGPITR 1856

Query: 968  YYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
            Y +  R   +G+     +   K VS   + +  LK  + Y F+V A+N  G G PS+ S+
Sbjct: 1857 YVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQ 1916

Query: 1028 CFKC-------EEWTIAV 1038
                       EEW   V
Sbjct: 1917 SVPAQKANPFYEEWWFLV 1934



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 10/113 (8%)

Query: 273 LLHAPEFIIKPRSHTVWEKENV-KLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESR 331
           +L  P+F+ +P  H   E E V  + C   G P P +TWYK+   + V     K     +
Sbjct: 304 VLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVE----KLTRFRQ 359

Query: 332 YGMHTLEINGCDFEDTAQYRASAMNVKGELS-----AYASVVVKRYKGEFDET 379
                L+I+G   +DT  ++  A N  GE+      A  S+     +G  D T
Sbjct: 360 RNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDST 412



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 63/277 (22%), Positives = 111/277 (40%), Gaps = 16/277 (5%)

Query: 927  KKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREA 986
            ++   AP  P   ++ +E  R ++ L W +P   G + +  Y +   E  +  P     A
Sbjct: 587  RQLPHAPEHPVATLSTVE--RRAINLTWTKPFD-GNSPLIRYILEMSE--NNAPWTVLLA 641

Query: 987  NV--KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHS 1044
            +V  KA S     +  L     YQF++ A+N  G G  S  +E     E     P  P +
Sbjct: 642  SVDPKATS---VTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAP--PQN 696

Query: 1045 LKCSEVRKDSLVLQWKPPVHSGRTPV-TGYFVDLKEAKAKED-QWRGLNEAAIKNVYLKV 1102
            +  S     S+++QW+PP  S +  +  GY +    A      Q++ + +A + N+ L+ 
Sbjct: 697  VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLE- 755

Query: 1103 RGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDK 1162
              L    +Y   V A N AG+G  S        +  P      V+ +     ++ F  + 
Sbjct: 756  -DLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA 814

Query: 1163 MTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKD 1199
             +P+     ++ Y      P  E E      +  F+D
Sbjct: 815  PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQD 851



 Score = 39.7 bits (91), Expect = 0.025
 Identities = 74/310 (23%), Positives = 120/310 (38%), Gaps = 56/310 (18%)

Query: 1368 VTGECNVLLKCKVANIKK--ETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGI 1425
            V G   V L+C VAN +   + HI+W KD   +S        D    L I   +  DAG 
Sbjct: 227  VAGTSEVTLEC-VANARPLIKLHIIWKKDGVLLS----GGISDHNRRLTIPNPTGSDAGY 281

Query: 1426 YE--VILKDD------RGKDKSRLK---LVDEAFKELMMEVCKKIALSATDLKIQSTAEG 1474
            YE   +L+        RG   S L+    V E  + +  E+ K +        I   A+G
Sbjct: 282  YECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVV-------DIPCQAKG 334

Query: 1475 IQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELF 1534
            +   S +T+Y +   V         R+  R   G       LQI+   P+D G +  + F
Sbjct: 335  VPPPS-ITWYKDAAVVEVE---KLTRFRQRNDGG-------LQISGLVPDDTGMF--QCF 381

Query: 1535 DGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTC 1594
                      + +G+     Y          +A  + A  +   P   T+ +G ++ L C
Sbjct: 382  --------ARNAAGEVQTSTY----------LAVTSIAPNITRGPLDSTVIDGMSVVLAC 423

Query: 1595 NVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGS 1654
               G P P ++W K E+ LAS      +F    +    I+    +D+G Y  +  N  G 
Sbjct: 424  ETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGV 483

Query: 1655 ETSDFTVSVF 1664
            + +   + V+
Sbjct: 484  DEASADLVVW 493



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 17/98 (17%)

Query: 1586 EGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYG 1645
            EG  L LTC   G  P E  WL N + L      +L++       + I  +    +G Y 
Sbjct: 40   EGNRLVLTCMAEGSWPLEFKWLHNNRELTK---FSLEYR------YMITSLDRTHAGFYR 90

Query: 1646 LVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGKK 1683
             +V+N+ G        ++   + E ++A + S + G+K
Sbjct: 91   CIVRNRMG--------ALLQRQTEVQVAYMGSFEEGEK 120


>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
            isoform 2 precursor [Homo sapiens]
          Length = 1910

 Score =  110 bits (275), Expect = 1e-23
 Identities = 209/917 (22%), Positives = 341/917 (37%), Gaps = 154/917 (16%)

Query: 263  TYHAKLN---EDHLLHA-PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPIN 318
            T HAKL    ED L    P   + P+   V       + C+ +G P+P +TW+K+ +P++
Sbjct: 117  TVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVD 176

Query: 319  VHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKG---ELSAYASVVVKRYKGE 375
              A+ G+ I + R G   L+I   +  D  +Y   A N  G      A   V V+R    
Sbjct: 177  PSASNGR-IKQLRSG--ALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPR 233

Query: 376  FDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIK 435
            F         S +P+S  + P                      G  +++ C  V +P   
Sbjct: 234  F---------SILPMSHEIMP----------------------GGNVNITCVAVGSP--- 259

Query: 436  HFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSA 495
               P ++W +    L+P   +       R  L  + +  +D   YT  V M       S 
Sbjct: 260  --MPYVKWMQGAEDLTPEDDMPV----GRNVLELTDV--KDSANYTC-VAMS------SL 304

Query: 496  YVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDS 555
             V    A   ++  P AP      E     I I+W     D   P+  Y I+      D 
Sbjct: 305  GVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPD---PVSYYVIEYKSKSQDG 361

Query: 556  WSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPS-----RVSEPVAALDPAE- 609
              Q  +  +   R+ + GL     Y   V AVN +G G PS     R  E   A  P   
Sbjct: 362  PYQIKED-ITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNV 420

Query: 610  KARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGI 669
            +AR+ S  +      +IV  EEP E      P  L                   RG+   
Sbjct: 421  QARMLSATT------MIVQWEEPVE------PNGLI------------------RGYR-- 448

Query: 670  MYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEV 729
            +Y+  + E    NWQ+ N +    S    +  L E ++Y  RV    S G G  S+  +V
Sbjct: 449  VYYTMEPEHPVGNWQKHNVD---DSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQV 505

Query: 730  TVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNN 789
                 +  +P  P  +     ++TS+ +SW   +  + ++ Y +       G+      +
Sbjct: 506  KT---QQGVPGQPMNLRAEARSETSITLSWSPPRQ-ESIIKYELLFREGDHGREVGRTFD 561

Query: 790  PVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS----------------QDSEAIEVKA 833
            P   + +    L     Y FR+ A +  GL  ++                QD + + V++
Sbjct: 562  PT--TSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRS 619

Query: 834  -AIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPS-LPSSSQNL 891
             AI     P   P      G L     R         +   + G  P     L  + +  
Sbjct: 620  TAILVSWRP---PPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKW 676

Query: 892  GQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDR-APPSPPCDITCLESFRDSM 950
             Q  ++ V+ T   E+ P P+         S P+  +TD   P +PP  +        ++
Sbjct: 677  TQYRITTVAHT---EVGPGPE---------SSPVVVRTDEDVPSAPPRKVEAEALNATAI 724

Query: 951  VLGWKQP-DKIGGAEITGYYVNYREVIDG-VPGKWREANVKAVSEEAYKISNLKENMVYQ 1008
             + W+ P       +I GY V+Y  +      G  R  +V     +   I+NL+    Y 
Sbjct: 725  RVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYS 784

Query: 1009 FQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRT 1068
              VAA  M G GA S      K      AV G P +L   +  + SL+ +W+PP  +   
Sbjct: 785  ITVAAYTMKGDGARSKP----KVVVTKGAVLGRP-TLSVQQTPEGSLLARWEPPAGTAED 839

Query: 1069 PVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
             V GY   L+  +        L     ++ Y    G+ +G +YVFR+ A ++ G+G+ + 
Sbjct: 840  QVLGY--RLQFGREDSTPLATLEFPPSEDRY-TASGVHKGATYVFRLAARSRGGLGEEAA 896

Query: 1129 LAGPVVAETRPGTKEVV 1145
                +  +T  G  +++
Sbjct: 897  EVLSIPEDTPRGHPQIL 913



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 194/947 (20%), Positives = 340/947 (35%), Gaps = 162/947 (17%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P FI +P+             C   G P+PRVTW K    +N          ES   +  
Sbjct: 33   PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTP 396
            ++      ++   Y   A N  GE++ +A + V R                +P  F    
Sbjct: 93   IQPLRTPRDENV-YECVAQNSVGEITVHAKLTVLR-------------EDQLPSGFP--- 135

Query: 397  YGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWV 456
                     + D    +       T ++ C     P+     PEI W+++ +P+ PS   
Sbjct: 136  ---------NIDMGPQLKVVERTRTATMLCAASGNPD-----PEITWFKDFLPVDPSASN 181

Query: 457  QTLWSGERATLTFSHLNKEDEGLYTIRVRMG---EYYEQYSAYVFVRDADAEI------- 506
              +       L      + D+G Y           Y    + YV VR             
Sbjct: 182  GRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSH 241

Query: 507  EGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKF 566
            E  P   +++ C+        + W Q                   G +  +  +D PV  
Sbjct: 242  EIMPGGNVNITCVAVGSPMPYVKWMQ-------------------GAEDLTPEDDMPVGR 282

Query: 567  ARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQII 626
                +T + +  +Y     A++ +G+            ++   +  +KS P AP T    
Sbjct: 283  NVLELTDVKDSANYT--CVAMSSLGV------------IEAVAQITVKSLPKAPGTPM-- 326

Query: 627  VTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRV 686
                               VTE T + + ++W        + + Y+V + ++ +++    
Sbjct: 327  -------------------VTENTATSITITWDSGNP---DPVSYYVIEYKSKSQDGPYQ 364

Query: 687  NTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKII 746
              E  + + R+++  L+    Y   V   NS G G PSE+  VT  G++     AP  + 
Sbjct: 365  IKE-DITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESV-VTRTGEQAPA-SAPRNVQ 421

Query: 747  PSRNTDTSVVVSWEESKDAKELVG----YYIEASVAGSGKWEPCNNNPVKGSRFTCHG-L 801
                + T+++V WEE  +   L+     YY        G W+  N   V  S  T  G L
Sbjct: 422  ARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHN---VDDSLLTTVGSL 478

Query: 802  VTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRV 861
            +  ++Y  RV A  + G       S+ I+VK   G    P    A +     +T S    
Sbjct: 479  LEDETYTVRVLAFTSVGDGPL---SDPIQVKTQQGVPGQPMNLRAEARSETSITLS---- 531

Query: 862  HEASPP---TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKA---- 914
               SPP   +  K  LL  + +        + +G+T     +  V E+L P  + A    
Sbjct: 532  --WSPPRQESIIKYELLFREGD------HGREVGRT-FDPTTSYVVEDLKPNTEYAFRLA 582

Query: 915  --APQGKSKSDP-LKKKTDRAPPS-PPCDITCLESFRDSMVLGWK-QPDKIGGAEITGYY 969
              +PQG     P ++++T ++ PS PP D+ C+     ++++ W+  P +     + GY 
Sbjct: 583  ARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYS 642

Query: 970  VNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECF 1029
            V YR +    P + +E N    +     +  L++   Y+    A    G G P +     
Sbjct: 643  VRYRPLGSEDP-EPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPG-PESSPVVV 700

Query: 1030 KCEEWTIAVP-GPPHSLKCSEVRKDSLVLQWKPPVHSGRT--PVTGY---FVDLKEAKAK 1083
            + +E    VP  PP  ++   +   ++ + W+ P   GR    + GY   +V ++ A+A+
Sbjct: 701  RTDE---DVPSAPPRKVEAEALNATAIRVLWRSPA-PGRQHGQIRGYQVHYVRMEGAEAR 756

Query: 1084 EDQWRGLNEAAIKNVYLK------VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET 1137
                       IK+V L       +  L+   +Y   V A    G G  S     V    
Sbjct: 757  -------GPPRIKDVMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGA 809

Query: 1138 RPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRL 1184
              G   + V    +G +   +E    T + +    +     EDS  L
Sbjct: 810  VLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGREDSTPL 856



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 1/71 (1%)

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST-ADSGKYG 1645
            G   +  C   GDP P V+W K  K + S     ++F+    A   I  + T  D   Y 
Sbjct: 47   GGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYE 106

Query: 1646 LVVKNKYGSET 1656
             V +N  G  T
Sbjct: 107  CVAQNSVGEIT 117



 Score = 34.7 bits (78), Expect = 0.80
 Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 1/75 (1%)

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
            P +  ++  +   + C   G+P PE++W K+   +      N + +  R+    I     
Sbjct: 141  PQLKVVERTRTATMLCAASGNPDPEITWFKDFLPV-DPSASNGRIKQLRSGALQIESSEE 199

Query: 1639 ADSGKYGLVVKNKYG 1653
             D GKY  V  N  G
Sbjct: 200  TDQGKYECVATNSAG 214


>gi|133908641 myosin binding protein C, fast type [Homo sapiens]
          Length = 1141

 Score =  110 bits (275), Expect = 1e-23
 Identities = 78/268 (29%), Positives = 116/268 (43%), Gaps = 39/268 (14%)

Query: 474 KEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQP 533
           +EDEG YTI+V      +  S ++ V D        P  P  V+     +D+ I+ W+ P
Sbjct: 610 REDEGRYTIKVTNPVGEDVASIFLQVVDV-------PDPPEAVRITSVGEDWAILVWEPP 662

Query: 534 AVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIG 593
             DGG P+ GY +++ + G+  W + N        +  T +IEG  Y  RV AVN +G+ 
Sbjct: 663 MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVS 722

Query: 594 FPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSY 653
            PS  ++P   + P  +                              P  L V + T + 
Sbjct: 723 QPSMNTKPFMPIAPTSE------------------------------PLHLIVEDVTDTT 752

Query: 654 VVLSWKPPGQRGHEGI-MYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRV 712
             L W+PP + G  GI  Y VE C  G+E W   NTE PV+   F + +L  G    FRV
Sbjct: 753 TTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTE-PVERCGFTVKNLPTGARILFRV 811

Query: 713 RCSNSAGVGEPSEATEVTVVGDKLDIPK 740
              N AG  EP+   +   + +  + PK
Sbjct: 812 VGVNIAGRSEPATLAQPVTIREIAEPPK 839



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 140/621 (22%), Positives = 233/621 (37%), Gaps = 103/621 (16%)

Query: 442  QWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRD 501
            +WY+NGV + PSK +     G    L    +  EDEG YT  V  G Y    SA +   +
Sbjct: 470  KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDG-YALSLSAKLNFLE 527

Query: 502  ADAEI---EGAPAAPLDVKCLEANKDYIIISWKQPAVD----GGSPILGYFIDKCEVGTD 554
               E    +  P   LD     +    ++++  +  +D    G  P +  ++   EV T 
Sbjct: 528  IKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTT 587

Query: 555  SWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLK 614
            +                    EGR+ I       +  +   S V E     D        
Sbjct: 588  T--------------------EGRTRI-------EKRVDCSSFVIESAQREDEGRYTIKV 620

Query: 615  SRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFV 673
            + P       I +   +     VP PP  + +T     + +L W+PP   G + +  Y V
Sbjct: 621  TNPVGEDVASIFLQVVD-----VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLV 675

Query: 674  EKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVG 733
            E+ + G++ W ++N E+  ++  +    + EG  Y  RV   N+ GV +PS  T+  +  
Sbjct: 676  ERKKKGSQRWMKLNFEVFTETT-YESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM-- 732

Query: 734  DKLDIPKAPGKIIPSRNTDTSVVVSWEESK--DAKELVGYYIEASVAGSGKWEPCNNNPV 791
              +     P  +I    TDT+  + W       A  + GY +E  + GS +W P N  PV
Sbjct: 733  -PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPV 791

Query: 792  KGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVK------------------- 832
            +   FT   L TG   +FRV  VN AG SE +  ++ + ++                   
Sbjct: 792  ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYI 851

Query: 833  AAIGGGVSPDV------CPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPS 886
              +G  ++  V       P +    GG      RVH     T   D +   +    S   
Sbjct: 852  RKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVR---TSDFDTVFFVRQAARSDSG 908

Query: 887  SSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESF 946
              +   Q E  K + T++  +    +KA P                    P ++   E +
Sbjct: 909  EYELSVQIENMKDTATIRIRVV---EKAGP--------------------PINVMVKEVW 945

Query: 947  RDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMV 1006
              + ++ W+ P   G +EI GY+V   +  D    +W     +     +  +S+L     
Sbjct: 946  GTNALVEWQAPKDDGNSEIMGYFV---QKADKKTMEWFNV-YERNRHTSCTVSDLIVGNE 1001

Query: 1007 YQFQVAAMNMAGLGAPSAVSE 1027
            Y F+V   N+ GL     VS+
Sbjct: 1002 YYFRVYTENICGLSDSPGVSK 1022



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 120/531 (22%), Positives = 206/531 (38%), Gaps = 55/531 (10%)

Query: 934  PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
            P PP  +       D  +L W+ P   GG  +TGY V  ++       +W + N +  +E
Sbjct: 639  PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQ---RWMKLNFEVFTE 695

Query: 994  EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
              Y+ + + E ++Y+ +V A+N  G+  PS  ++ F      IA    P  L   +V   
Sbjct: 696  TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPF----MPIAPTSEPLHLIVEDVTDT 751

Query: 1054 SLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVF 1113
            +  L+W+PP   G   + GY V+        ++W   N   ++     V+ L  G   +F
Sbjct: 752  TTTLKWRPPNRIGAGGIDGYLVEY--CLEGSEEWVPANTEPVERCGFTVKNLPTGARILF 809

Query: 1114 RVRAINQAGVGKPSDLAGPV----VAE------TRPGTKEVVVNVDDDGVISLNFECDKM 1163
            RV  +N AG  +P+ LA PV    +AE       R   +  +  V +   + + F+    
Sbjct: 810  RVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQ---G 866

Query: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223
             P+ +  W+K      D+ R+ V +    T    +     D G Y   V           
Sbjct: 867  KPRPQVVWTKGGAPL-DTSRVHVRTSDFDTVFFVRQAARSDSGEYELSV----------- 914

Query: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKE 1283
               E +K    +         P  + +  E+     +  W QA K  GN+++   F +K 
Sbjct: 915  -QIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEW-QAPKDDGNSEIMGYFVQKA 972

Query: 1284 IFEGPKYKMHIDRNTGIIEMFMEKLQDED-------EGTYTFQLQDGKATNHSTVVLVGD 1336
              +  ++    +RN        + +   +       E         G + N + ++  G 
Sbjct: 973  DKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGI 1032

Query: 1337 VFKKLQ-KEAEFQRQEWIRKQGPHFV-EYLSWEVTGECNVLLKCKVANIKKETHIVWYKD 1394
             FK  + KE +F       +  P F+   +   V    +  L C V    K   +VW K+
Sbjct: 1033 TFKPFEYKEHDF-------RMAPKFLTPLIDRVVVAGYSAALNCAVRGHPK-PKVVWMKN 1084

Query: 1395 EREISVDEKHDFKD--GICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
            + EI  D K    +  G+ TL I   S  DAG Y     ++ G+  +  KL
Sbjct: 1085 KMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKL 1135



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 39/117 (33%), Positives = 59/117 (50%), Gaps = 4/117 (3%)

Query: 1036 IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 1095
            + VP PP +++ + V +D  +L W+PP++ G  PVTGY V+ K  K    +W  LN    
Sbjct: 636  VDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERK--KKGSQRWMKLNFEVF 693

Query: 1096 KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPV--VAETRPGTKEVVVNVDD 1150
                 +   + EG+ Y  RV A+N  GV +PS    P   +A T      +V +V D
Sbjct: 694  TETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTD 750



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 74/303 (24%), Positives = 130/303 (42%), Gaps = 44/303 (14%)

Query: 1389 IVWYKD----EREISVDEKHDFK-DGICTLLI-TEFSKKDAGIYEVILKDDRGKDKSRLK 1442
            ++W KD     RE S   ++ FK DG   +LI ++  ++D G Y+VI     G+ ++ L 
Sbjct: 376  VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNG--GQCEAELI 433

Query: 1443 LVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVN--WSHNGSAIR 1500
            +     +E  +EV + IA    DL ++++ + +         V D KV   W  NG  +R
Sbjct: 434  V-----EEKQLEVLQDIA----DLTVKASEQAV-----FKCEVSDEKVTGKWYKNGVEVR 479

Query: 1501 YSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQR 1560
             S R+     G    L I++  P D+G Y   + DG       + LS      A   F  
Sbjct: 480  PSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGYA-----LSLS------AKLNFLE 527

Query: 1561 LKQAAIAEKNRARV---LGGLP--DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALAS 1615
            +K   + ++   ++     G    + + +  G  L L  ++ G+PPP  +WLK ++   +
Sbjct: 528  IKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTT 587

Query: 1616 DDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDF---TVSVFIPEEEARM 1672
             +      +    + F I      D G+Y + V N  G + +      V V  P E  R+
Sbjct: 588  TEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRI 647

Query: 1673 AAL 1675
             ++
Sbjct: 648  TSV 650



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 43/168 (25%), Positives = 70/168 (41%), Gaps = 9/168 (5%)

Query: 438  QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
            +P++ W + G PL  S+ V    S            + D G Y + V++    +  +  +
Sbjct: 869  RPQVVWTKGGAPLDTSR-VHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRI 927

Query: 498  FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
             V      +E A   P++V   E      ++ W+ P  DG S I+GYF+ K +  T  W 
Sbjct: 928  RV------VEKA-GPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWF 980

Query: 558  QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAAL 605
               +   +     V+ LI G  Y FRV   N  G+     VS+  A +
Sbjct: 981  NVYERN-RHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 88/415 (21%), Positives = 157/415 (37%), Gaps = 59/415 (14%)

Query: 932  APPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAV 991
            AP S P  +   +    +  L W+ P++IG   I GY V Y   ++G   +W  AN + V
Sbjct: 735  APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEY--CLEG-SEEWVPANTEPV 791

Query: 992  SEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGP---PHSLKCS 1048
                + + NL       F+V  +N+AG   P+ +++     E  IA P     P  L+ +
Sbjct: 792  ERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIRE--IAEPPKIRLPRHLRQT 849

Query: 1049 EVRKDSLVLQWKPPVHSGRTPVT-----GYFVDLKEAKAKEDQW--------RGLNEAAI 1095
             +RK    L    P      P       G  +D      +   +           +++  
Sbjct: 850  YIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGE 909

Query: 1096 KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVV--VNVDDDGV 1153
              + +++  +K+  +   R+R + +A  G P +    V+ +   GT  +V      DDG 
Sbjct: 910  YELSVQIENMKD--TATIRIRVVEKA--GPPIN----VMVKEVWGTNALVEWQAPKDDGN 961

Query: 1154 ISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDD---LGIYS- 1209
              +     +   K    W              V  +   T  T  DL + +     +Y+ 
Sbjct: 962  SEIMGYFVQKADKKTMEW------------FNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1009

Query: 1210 --CDVTDTDGIASSYLIDEEELKRLLALS----HEHKFPTVP-VKSELAVEILEKGQVRF 1262
              C ++D+ G++ +       LK  +        EH F   P   + L   ++  G    
Sbjct: 1010 NICGLSDSPGVSKN---TARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAA 1066

Query: 1263 WMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT 1317
               A +     KV ++ N+ EI E PK+   I    G++ + + +    D GTYT
Sbjct: 1067 LNCAVRGHPKPKVVWMKNKMEIREDPKFL--ITNYQGVLTLNIRRPSPFDAGTYT 1119



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 139/679 (20%), Positives = 242/679 (35%), Gaps = 110/679 (16%)

Query: 910  PPQKAAPQGKSKSDPLKKKTDRAPP-SPPCDITCLESFRDSMVLGWKQPDKIGG------ 962
            P  K AP+G  K  P K+    AP  +PP D +        + L  K+PD +        
Sbjct: 12   PKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFL--KKPDSVSVETGKDA 69

Query: 963  ---AEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVY--QFQVAAMNMA 1017
               A++ G  +  +  I    GKW E   K+ +  ++K S+   + VY  +  +  + + 
Sbjct: 70   VVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLG 129

Query: 1018 GLG----APSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPV-----HSGRT 1068
              G       A   C  C  + I V  P        +       + K         SG  
Sbjct: 130  DRGYYRLEVKAKDTCDSCG-FNIDVEAPRQDASGQSLESFKRTSEKKSDTAGELDFSGLL 188

Query: 1069 PVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLK--EGVSYVFRVRAINQAGVGKP 1126
                   + K+ K K+D   G+       ++  ++G K  E     F+    +  G+ K 
Sbjct: 189  KKREVVEEEKKKKKKDDDDLGIPP----EIWELLKGAKKSEYEKIAFQYGITDLRGMLKR 244

Query: 1127 SDLAGPVVAETRPGTKEV--VVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRL 1184
               A   V ++   TK++     VD    I L  E     P     W K+    + S + 
Sbjct: 245  LKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISD--PDLTLKWFKNGQEIKPSSKY 302

Query: 1185 EVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTV 1244
              E+ G K  +T     + D   Y   V D       ++   +E   L+    E +   V
Sbjct: 303  VFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFV---KEPPVLIVTPLEDQQVFV 359

Query: 1245 PVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMF 1304
              + E+AVE+ E+G    WM         K       ++ F+  +Y+   D    I+ +F
Sbjct: 360  GDRVEMAVEVSEEGAQVMWM---------KDGVELTREDSFKA-RYRFKKDGKRHIL-IF 408

Query: 1305 MEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYL 1364
             + +Q ED G Y      G                  Q EAE   +E   KQ     +  
Sbjct: 409  SDVVQ-EDRGRYQVITNGG------------------QCEAELIVEE---KQLEVLQDIA 446

Query: 1365 SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAG 1424
               V      + KC+V++ K      WYK+  E+   ++         + I+   +    
Sbjct: 447  DLTVKASEQAVFKCEVSDEKVTGK--WYKNGVEVRPSKR---------ITISHVGR---- 491

Query: 1425 IYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYY 1484
             +++++ D R +D+     V + +      +     L+  ++K++              Y
Sbjct: 492  FHKLVIDDVRPEDEGDYTFVPDGY-----ALSLSAKLNFLEIKVE--------------Y 532

Query: 1485 VEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQIN---EPTPND---KGKYVMELFDGKT 1538
            V   +    H   + + S+     V G ++ L ++   EP P     KG  V    +G+T
Sbjct: 533  VPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRT 592

Query: 1539 GHQKTVDLSGQAYDEAYAE 1557
              +K VD S    + A  E
Sbjct: 593  RIEKRVDCSSFVIESAQRE 611



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 276  APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
            AP+F+       V    +  L+C++ G P+P+V W KN++ I       K++I +  G+ 
Sbjct: 1047 APKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIR---EDPKFLITNYQGVL 1103

Query: 336  TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
            TL I      D   Y   A+N  GE  A   + V+
Sbjct: 1104 TLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 48/217 (22%), Positives = 79/217 (36%), Gaps = 53/217 (24%)

Query: 294 VKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRAS 353
           +KL   I+  P+  + W+KN   I   +   KY+ E+      L IN C   D A Y  +
Sbjct: 274 IKLMVEISD-PDLTLKWFKNGQEIKPSS---KYVFENVGKKRILTINKCTLADDAAYEVA 329

Query: 354 AMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDV 413
             + K     +  + VK                  P    VTP                 
Sbjct: 330 VKDEK----CFTELFVKE-----------------PPVLIVTPL---------------- 352

Query: 414 SFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLW----SGERATLTF 469
               E + + +G RV +  E+     ++ W ++GV L+     +  +     G+R  L F
Sbjct: 353 ----EDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIF 408

Query: 470 SHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEI 506
           S + +ED G Y +    G    Q  A + V +   E+
Sbjct: 409 SDVVQEDRGRYQVITNGG----QCEAELIVEEKQLEV 441



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 11/118 (9%)

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPE---VSWLKNE-KALASDDHCNLKFEAGR------- 1627
            PD V+++ GK   +   V G   P+   + W K +   L S       F+          
Sbjct: 58   PDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVY 117

Query: 1628 TAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGKKAK 1685
            T    I  V   D G Y L VK K   ++  F + V  P ++A   +LES K   + K
Sbjct: 118  TVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKK 175



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 37/181 (20%), Positives = 75/181 (41%), Gaps = 10/181 (5%)

Query: 1158 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
            F+C+    K    W K+ V    S R+ +   G   K+   D+  +D G Y+  V D   
Sbjct: 458  FKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTF-VPDGYA 516

Query: 1218 IASSYLIDEEELKRLLALSHEHKFPTVPV-----KSELAVEILEKGQVRFWMQAEKLSGN 1272
            ++ S  ++  E+K  +    + + P + +      SE A+ ++   ++R  +        
Sbjct: 517  LSLSAKLNFLEIK--VEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLR--LDVSITGEP 572

Query: 1273 AKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVV 1332
              V       E+F   + +  I++        +E  Q EDEG YT ++ +    + +++ 
Sbjct: 573  PPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIF 632

Query: 1333 L 1333
            L
Sbjct: 633  L 633



 Score = 35.4 bits (80), Expect = 0.47
 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 1/81 (1%)

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
            G +  L C V G P P+V W+KN+  +  D    +    G      I   S  D+G Y  
Sbjct: 1062 GYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQG-VLTLNIRRPSPFDAGTYTC 1120

Query: 1647 VVKNKYGSETSDFTVSVFIPE 1667
               N+ G   ++  + V +P+
Sbjct: 1121 RAVNELGEALAECKLEVRVPQ 1141



 Score = 34.7 bits (78), Expect = 0.80
 Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 4/120 (3%)

Query: 1544 VDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPE 1603
            V+++G++     A+   +++  IAE  + R+   L      + G+ LNL     G P P+
Sbjct: 814  VNIAGRSEPATLAQPVTIRE--IAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQ 871

Query: 1604 VSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
            V W K    L      +++     T +F +   + +DSG+Y L V+ +   +T+   + V
Sbjct: 872  VVWTKGGAPL-DTSRVHVRTSDFDTVFF-VRQAARSDSGEYELSVQIENMKDTATIRIRV 929



 Score = 31.2 bits (69), Expect = 8.9
 Identities = 20/67 (29%), Positives = 25/67 (37%), Gaps = 2/67 (2%)

Query: 294 VKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRAS 353
           ++L  SI G P P  TW K           G+  IE R    +  I     ED  +Y   
Sbjct: 562 LRLDVSITGEPPPVATWLKGDEVFT--TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIK 619

Query: 354 AMNVKGE 360
             N  GE
Sbjct: 620 VTNPVGE 626


>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
            precursor [Homo sapiens]
          Length = 1899

 Score =  110 bits (274), Expect = 2e-23
 Identities = 193/897 (21%), Positives = 333/897 (37%), Gaps = 159/897 (17%)

Query: 268  LNEDHLLHA-PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKY 326
            L ED +    P   + P+   V       + C+ +G P+P +TW+K+ +P++   N G+ 
Sbjct: 116  LREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR- 174

Query: 327  IIESRYGMHTLEINGCDFEDTAQYRASAMNVKG-ELSAYASVVVKRYKGEFDETRFHAGA 385
            I + R G   L+I   +  D  +Y   A N  G   SA A++ V+               
Sbjct: 175  IKQLRSG--ALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVR--------------V 218

Query: 386  STMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYR 445
              +P  F + P  +    EI             G ++++ C  V +P      P ++W  
Sbjct: 219  RRVPPRFSIPPTNH----EI-----------MPGGSVNITCVAVGSP-----MPYVKWML 258

Query: 446  NGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAE 505
                L+P   +       R  L  + + +           +G         V    A   
Sbjct: 259  GAEDLTPEDDMPI----GRNVLELNDVRQSANYTCVAMSTLG---------VIEAIAQIT 305

Query: 506  IEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPI-LGYFIDKCEVGTDSWSQCNDTPV 564
            ++  P  P      E+    I ++W     D G+P  + Y+I + +             V
Sbjct: 306  VKALPKPPGTPVVTESTATSITLTW-----DSGNPEPVSYYIIQHKPKNSEELYKEIDGV 360

Query: 565  KFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQ 624
               R+ V GL     Y FRV AVN +G G P   SEPV                      
Sbjct: 361  ATTRYSVAGLSPYSDYEFRVVAVNNIGRGPP---SEPVLTQ------------------- 398

Query: 625  IIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQ-----RGHEGIMYFVEKCEAG 679
               +E+ PS       P D+     + + +++ WK P +     +G+   +Y+       
Sbjct: 399  --TSEQAPSSA-----PRDVQARMLSSTTILVQWKEPEEPNGQIQGYR--VYYTMDPTQH 449

Query: 680  TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 739
              NW + N      S    + +L   K+Y  +V    S G G  S   +V     +  +P
Sbjct: 450  VNNWMKHNV---ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVIT---QTGVP 503

Query: 740  KAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCH 799
              P        ++TS+++SW   + +  +  Y +       G+ +     P  G+ +   
Sbjct: 504  GQPLNFKAEPESETSILLSWTPPR-SDTIANYELVYKDGEHGEEQRITIEP--GTSYRLQ 560

Query: 800  GLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPA-------LSDEPG 852
            GL     Y FR+ A +  GL   + +  A  +++          C +       +S +P 
Sbjct: 561  GLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPP 620

Query: 853  GLTASRGRVHEASPPTFQKDALLGSKPNKP----SLPSSS-----QNLGQTEVSKVSETV 903
             +    G + E S     K   +  + +KP     +PS +     + L +    +++ T 
Sbjct: 621  PVEKQNGIITEYS----IKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTA 676

Query: 904  QEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQ--PDKIG 961
              ++ P P+  +   ++  D         P  PP  +        S+ + W+   P+K  
Sbjct: 677  HTDVGPGPESLSVLIRTNED--------VPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQH 728

Query: 962  GAEITGYYVNYREVIDGVP-------------GKWREANVKAVSEEAYKISNLKENMVYQ 1008
            G +I GY V+Y  + +G P              +W        +E    IS L+    Y 
Sbjct: 729  G-QIRGYQVHYVRMENGEPKGQPMLKDVMLADAQW---EFDDTTEHDMIISGLQPETSYS 784

Query: 1009 FQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRT 1068
              V A    G GA S      K    T AVPG P  L  +  + ++ ++QW PPV +   
Sbjct: 785  LTVTAYTTKGDGARSKP----KLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDT-FG 838

Query: 1069 PVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGK 1125
            P+ GY   LK  +   +    L E + K  +     + +G SYVFR+ A N+ G G+
Sbjct: 839  PLQGY--RLKFGRKDMEPLTTL-EFSEKEDHFTATDIHKGASYVFRLSARNKVGFGE 892



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 98/454 (21%), Positives = 172/454 (37%), Gaps = 50/454 (11%)

Query: 689  ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPS 748
            ++P+      L D+ +  +Y     C   + +G      ++TV      +PK PG  + +
Sbjct: 268  DMPIGRNVLELNDVRQSANYT----CVAMSTLGVIEAIAQITVKA----LPKPPGTPVVT 319

Query: 749  RNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYI 808
             +T TS+ ++W+      E V YYI      + +      + V  +R++  GL     Y 
Sbjct: 320  ESTATSITLTWDSGNP--EPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYE 377

Query: 809  FRVRAVNAAG-----------LSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTAS 857
            FRV AVN  G            SE +  S   +V+A +    +  V     +EP G    
Sbjct: 378  FRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQG 437

Query: 858  RGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQ 917
              RV+    PT   +  +              N+  ++++ +   V ++       A   
Sbjct: 438  Y-RVYYTMDPTQHVNNWM------------KHNVADSQITTIGNLVPQKTYSVKVLAFTS 484

Query: 918  ---GKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYRE 974
               G   SD ++  T    P  P +         S++L W  P       I  Y + Y+ 
Sbjct: 485  IGDGPLSSD-IQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS---DTIANYELVYK- 539

Query: 975  VIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEW 1034
              DG  G+  E  +      +Y++  LK N +Y F++AA +  GLGA +A       +  
Sbjct: 540  --DGEHGE--EQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSK 595

Query: 1035 TIAVPGPPHSLKCSEVRKDSLVLQWK-PPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
              A   PP  + C+     S+++ W+ PPV      +T Y +       ++D+   +   
Sbjct: 596  PSA---PPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGI 652

Query: 1094 AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS 1127
                    +  L++   Y   V A    G G  S
Sbjct: 653  PSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPES 686



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 1037 AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIK 1096
            A+P PP +   +E    S+ L W     SG      Y++   + K  E+ ++ ++  A  
Sbjct: 308  ALPKPPGTPVVTESTATSITLTWD----SGNPEPVSYYIIQHKPKNSEELYKEIDGVATT 363

Query: 1097 NVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET 1137
                 V GL     Y FRV A+N  G G PS+   PV+ +T
Sbjct: 364  RY--SVAGLSPYSDYEFRVVAVNNIGRGPPSE---PVLTQT 399



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 10/128 (7%)

Query: 635 GIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNT-ELPVK 693
           G VPG P  L +     +  ++ W PP         Y   + + G ++ + + T E   K
Sbjct: 808 GAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQGY---RLKFGRKDMEPLTTLEFSEK 863

Query: 694 SPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKA-PGKIIPSRNTD 752
              F   D+ +G SY FR+   N  G GE      V  +    ++P   P  +     T 
Sbjct: 864 EDHFTATDIHKGASYVFRLSARNKVGFGEEM----VKEISIPEEVPTGFPQNLHSEGTTS 919

Query: 753 TSVVVSWE 760
           TSV +SW+
Sbjct: 920 TSVQLSWQ 927



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 19/79 (24%), Positives = 37/79 (46%), Gaps = 1/79 (1%)

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
            P +  ++  +   + C   G+P PE++W K+   + + ++ N + +  R+    I     
Sbjct: 132  PQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNN-NGRIKQLRSGALQIEQSEE 190

Query: 1639 ADSGKYGLVVKNKYGSETS 1657
            +D GKY  V  N  G+  S
Sbjct: 191  SDQGKYECVATNSAGTRYS 209



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 1/68 (1%)

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST-ADSGKYG 1645
            G   +  C   GDP P++ W K  K +++     ++F+ G  +   I  + T  D   Y 
Sbjct: 38   GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97

Query: 1646 LVVKNKYG 1653
             V  N  G
Sbjct: 98   CVASNNVG 105


>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
            precursor [Homo sapiens]
          Length = 1912

 Score =  108 bits (270), Expect = 4e-23
 Identities = 195/903 (21%), Positives = 334/903 (36%), Gaps = 158/903 (17%)

Query: 268  LNEDHLLHA-PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPG-- 324
            L ED +    P   + P+   V       + C+ +G P+P +TW+K+ +P++   N G  
Sbjct: 116  LREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRI 175

Query: 325  KYIIESRYG----MHTLEINGCDFEDTAQYRASAMNVKG-ELSAYASVVVKRYKGEFDET 379
            K +     G       L+I   +  D  +Y   A N  G   SA A++ V+    E  E 
Sbjct: 176  KQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVR----ELREV 231

Query: 380  RFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQP 439
            R       +P  F + P  +    EI             G ++++ C  V +P      P
Sbjct: 232  R------RVPPRFSIPPTNH----EI-----------MPGGSVNITCVAVGSP-----MP 265

Query: 440  EIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFV 499
             ++W      L+P   +       R  L  + + +           +G         V  
Sbjct: 266  YVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQSANYTCVAMSTLG---------VIE 312

Query: 500  RDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPI-LGYFIDKCEVGTDSWSQ 558
              A   ++  P  P      E+    I ++W     D G+P  + Y+I + +        
Sbjct: 313  AIAQITVKALPKPPGTPVVTESTATSITLTW-----DSGNPEPVSYYIIQHKPKNSEELY 367

Query: 559  CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
                 V   R+ V GL     Y FRV AVN +G G P   SEPV                
Sbjct: 368  KEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPP---SEPVLTQ------------- 411

Query: 619  APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQ-----RGHEGIMYFV 673
                     +E+ PS       P D+     + + +++ WK P +     +G+   +Y+ 
Sbjct: 412  --------TSEQAPSSA-----PRDVQARMLSSTTILVQWKEPEEPNGQIQGYR--VYYT 456

Query: 674  EKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVG 733
                    NW + N      S    + +L   K+Y  +V    S G G  S   +V    
Sbjct: 457  MDPTQHVNNWMKHNV---ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVIT-- 511

Query: 734  DKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKG 793
             +  +P  P        ++TS+++SW   + +  +  Y +       G+ +     P  G
Sbjct: 512  -QTGVPGQPLNFKAEPESETSILLSWTPPR-SDTIANYELVYKDGEHGEEQRITIEP--G 567

Query: 794  SRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPA------- 846
            + +   GL     Y FR+ A +  GL   + +  A  +++          C +       
Sbjct: 568  TSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSIL 627

Query: 847  LSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKP----SLPSSS-----QNLGQTEVS 897
            +S +P  +    G + E S     K   +  + +KP     +PS +     + L +    
Sbjct: 628  VSWQPPPVEKQNGIITEYS----IKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEY 683

Query: 898  KVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQ- 956
            +++ T   ++ P P+  +   ++  D         P  PP  +        S+ + W+  
Sbjct: 684  RITVTAHTDVGPGPESLSVLIRTNED--------VPSGPPRKVEVEAVNSTSVKVSWRSP 735

Query: 957  -PDKIGGAEITGYYVNYREVIDGVP-------------GKWREANVKAVSEEAYKISNLK 1002
             P+K  G +I GY V+Y  + +G P              +W        +E    IS L+
Sbjct: 736  VPNKQHG-QIRGYQVHYVRMENGEPKGQPMLKDVMLADAQW---EFDDTTEHDMIISGLQ 791

Query: 1003 ENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPP 1062
                Y   V A    G GA S      K    T AVPG P  L  +  + ++ ++QW PP
Sbjct: 792  PETSYSLTVTAYTTKGDGARSKP----KLVSTTGAVPGKPR-LVINHTQMNTALIQWHPP 846

Query: 1063 VHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAG 1122
            V +   P+ GY   LK  +   +    L E + K  +     + +G SYVFR+ A N+ G
Sbjct: 847  VDT-FGPLQGY--RLKFGRKDMEPLTTL-EFSEKEDHFTATDIHKGASYVFRLSARNKVG 902

Query: 1123 VGK 1125
             G+
Sbjct: 903  FGE 905



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 98/454 (21%), Positives = 172/454 (37%), Gaps = 50/454 (11%)

Query: 689  ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPS 748
            ++P+      L D+ +  +Y     C   + +G      ++TV      +PK PG  + +
Sbjct: 281  DMPIGRNVLELNDVRQSANYT----CVAMSTLGVIEAIAQITVKA----LPKPPGTPVVT 332

Query: 749  RNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYI 808
             +T TS+ ++W+      E V YYI      + +      + V  +R++  GL     Y 
Sbjct: 333  ESTATSITLTWDSGNP--EPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYE 390

Query: 809  FRVRAVNAAG-----------LSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTAS 857
            FRV AVN  G            SE +  S   +V+A +    +  V     +EP G    
Sbjct: 391  FRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQG 450

Query: 858  RGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQ 917
              RV+    PT   +  +              N+  ++++ +   V ++       A   
Sbjct: 451  Y-RVYYTMDPTQHVNNWM------------KHNVADSQITTIGNLVPQKTYSVKVLAFTS 497

Query: 918  ---GKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYRE 974
               G   SD ++  T    P  P +         S++L W  P       I  Y + Y+ 
Sbjct: 498  IGDGPLSSD-IQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS---DTIANYELVYK- 552

Query: 975  VIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEW 1034
              DG  G+  E  +      +Y++  LK N +Y F++AA +  GLGA +A       +  
Sbjct: 553  --DGEHGE--EQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSK 608

Query: 1035 TIAVPGPPHSLKCSEVRKDSLVLQWK-PPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
              A   PP  + C+     S+++ W+ PPV      +T Y +       ++D+   +   
Sbjct: 609  PSA---PPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGI 665

Query: 1094 AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPS 1127
                    +  L++   Y   V A    G G  S
Sbjct: 666  PSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPES 699



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 53/241 (21%), Positives = 94/241 (39%), Gaps = 27/241 (11%)

Query: 1389 IVWYKDEREISVD--EKHDFKDGICTLLITE--FSKKDAGIYEVILKDDRGKDKSRLKL- 1443
            IVW K  +++S    E  +F DG  ++L  +   + +D  IYE +  ++ G+     +L 
Sbjct: 55   IVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLT 114

Query: 1444 ------VDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGS 1497
                  +   F  + M    K+        +   A G      +T++ + L V+ S+N  
Sbjct: 115  VLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASG-NPDPEITWFKDFLPVDTSNNNG 173

Query: 1498 AIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAE 1557
             I+       G T  +  LQI +   +D+GKY                ++  +    Y+ 
Sbjct: 174  RIKQLRSESIGGTPIRGALQIEQSEESDQGKYEC--------------VATNSAGTRYSA 219

Query: 1558 FQRLKQAAIAEKNRARVLGGLPDV-VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASD 1616
               L    + E  R      +P     I  G ++N+TC   G P P V W+   + L  +
Sbjct: 220  PANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPE 279

Query: 1617 D 1617
            D
Sbjct: 280  D 280



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 37/140 (26%), Positives = 53/140 (37%), Gaps = 15/140 (10%)

Query: 231 QQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWE 290
           Q EE+ + K   V       R S    L     Y  +L E   +  P F I P +H +  
Sbjct: 196 QSEESDQGKYECVATNSAGTRYSAPANL-----YVRELREVRRV-PPRFSIPPTNHEIMP 249

Query: 291 KENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQY 350
             +V + C   G P P V W      +           +   G + LE+N  D   +A Y
Sbjct: 250 GGSVNITCVAVGSPMPYVKWMLGAEDLTPED-------DMPIGRNVLELN--DVRQSANY 300

Query: 351 RASAMNVKGELSAYASVVVK 370
              AM+  G + A A + VK
Sbjct: 301 TCVAMSTLGVIEAIAQITVK 320



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 1037 AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIK 1096
            A+P PP +   +E    S+ L W     SG      Y++   + K  E+ ++ ++  A  
Sbjct: 321  ALPKPPGTPVVTESTATSITLTWD----SGNPEPVSYYIIQHKPKNSEELYKEIDGVATT 376

Query: 1097 NVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAET 1137
                 V GL     Y FRV A+N  G G PS+   PV+ +T
Sbjct: 377  RY--SVAGLSPYSDYEFRVVAVNNIGRGPPSE---PVLTQT 412



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 34/128 (26%), Positives = 53/128 (41%), Gaps = 10/128 (7%)

Query: 635 GIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNT-ELPVK 693
           G VPG P  L +     +  ++ W PP         Y   + + G ++ + + T E   K
Sbjct: 821 GAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQGY---RLKFGRKDMEPLTTLEFSEK 876

Query: 694 SPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKA-PGKIIPSRNTD 752
              F   D+ +G SY FR+   N  G GE      V  +    ++P   P  +     T 
Sbjct: 877 EDHFTATDIHKGASYVFRLSARNKVGFGEEM----VKEISIPEEVPTGFPQNLHSEGTTS 932

Query: 753 TSVVVSWE 760
           TSV +SW+
Sbjct: 933 TSVQLSWQ 940



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 1/68 (1%)

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST-ADSGKYG 1645
            G   +  C   GDP P++ W K  K +++     ++F+ G  +   I  + T  D   Y 
Sbjct: 38   GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97

Query: 1646 LVVKNKYG 1653
             V  N  G
Sbjct: 98   CVASNNVG 105


>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
            isoform 1 precursor [Homo sapiens]
          Length = 1948

 Score =  105 bits (261), Expect = 5e-22
 Identities = 207/930 (22%), Positives = 343/930 (36%), Gaps = 158/930 (16%)

Query: 263  TYHAKLN---EDHLLHA-PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPIN 318
            T HAKL    ED L    P   + P+   V       + C+ +G P+P +TW+K+ +P++
Sbjct: 117  TVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVD 176

Query: 319  VHANPGKY------IIESRYGMHTLEINGCDFEDTAQYRASAMNVKG-ELSAYASVVVKR 371
              A+ G+         ES      L+I   +  D  +Y   A N  G   S+ A++ V+ 
Sbjct: 177  PSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRE 236

Query: 372  YKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVIT 431
             +   +  R     S +P+S  + P                      G  +++ C  V +
Sbjct: 237  LR---EVRRVAPRFSILPMSHEIMP----------------------GGNVNITCVAVGS 271

Query: 432  PEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYE 491
            P      P ++W +    L+P   +       R  L  + +  +D   YT  V M     
Sbjct: 272  P-----MPYVKWMQGAEDLTPEDDMPV----GRNVLELTDV--KDSANYTC-VAMS---- 315

Query: 492  QYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEV 551
              S  V    A   ++  P AP      E     I I+W     D   P+  Y I+    
Sbjct: 316  --SLGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPD---PVSYYVIEYKSK 370

Query: 552  GTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPS-----RVSEPVAALD 606
              D   Q  +  +   R+ + GL     Y   V AVN +G G PS     R  E   A  
Sbjct: 371  SQDGPYQIKED-ITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASA 429

Query: 607  PAE-KARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRG 665
            P   +AR+ S  +      +IV  EEP E      P  L                   RG
Sbjct: 430  PRNVQARMLSATT------MIVQWEEPVE------PNGLI------------------RG 459

Query: 666  HEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSE 725
            +   +Y+  + E    NWQ+ N +    S    +  L E ++Y  RV    S G G  S+
Sbjct: 460  YR--VYYTMEPEHPVGNWQKHNVD---DSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSD 514

Query: 726  ATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEP 785
              +V     +  +P  P  +     ++TS+ +SW   +  + ++ Y +       G+   
Sbjct: 515  PIQVKT---QQGVPGQPMNLRAEARSETSITLSWSPPRQ-ESIIKYELLFREGDHGREVG 570

Query: 786  CNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS----------------QDSEAI 829
               +P   + +    L     Y FR+ A +  GL  ++                QD + +
Sbjct: 571  RTFDPT--TSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCV 628

Query: 830  EVKA-AIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPS-LPSS 887
             V++ AI     P   P      G L     R         +   + G  P     L  +
Sbjct: 629  SVRSTAILVSWRP---PPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEA 685

Query: 888  SQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDR-APPSPPCDITCLESF 946
             +   Q  ++ V+ T   E+ P P+         S P+  +TD   P +PP  +      
Sbjct: 686  LEKWTQYRITTVAHT---EVGPGPE---------SSPVVVRTDEDVPSAPPRKVEAEALN 733

Query: 947  RDSMVLGWKQP-DKIGGAEITGYYVNYREV----------IDGVPGKWREANVKAVSEEA 995
              ++ + W+ P       +I GY V+Y  +          I  V     +      +E  
Sbjct: 734  ATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYE 793

Query: 996  YKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSL 1055
              I+NL+    Y   VAA  M G GA S      K      AV G P +L   +  + SL
Sbjct: 794  MVITNLQPETAYSITVAAYTMKGDGARSKP----KVVVTKGAVLGRP-TLSVQQTPEGSL 848

Query: 1056 VLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRV 1115
            + +W+PP  +    V GY   L+  +        L     ++ Y    G+ +G +YVFR+
Sbjct: 849  LARWEPPAGTAEDQVLGY--RLQFGREDSTPLATLEFPPSEDRY-TASGVHKGATYVFRL 905

Query: 1116 RAINQAGVGKPSDLAGPVVAETRPGTKEVV 1145
             A ++ G+G+ +     +  +T  G  +++
Sbjct: 906  AARSRGGLGEEAAEVLSIPEDTPRGHPQIL 935



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 197/966 (20%), Positives = 346/966 (35%), Gaps = 178/966 (18%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHT 336
            P FI +P+             C   G P+PRVTW K    +N          ES   +  
Sbjct: 33   PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92

Query: 337  LEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTP 396
            ++      ++   Y   A N  GE++ +A + V R                +P  F    
Sbjct: 93   IQPLRTPRDENV-YECVAQNSVGEITVHAKLTVLR-------------EDQLPSGFP--- 135

Query: 397  YGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKW- 455
                     + D    +       T ++ C     P+     PEI W+++ +P+ PS   
Sbjct: 136  ---------NIDMGPQLKVVERTRTATMLCAASGNPD-----PEITWFKDFLPVDPSASN 181

Query: 456  --VQTLWSGE------RATLTFSHLNKEDEGLYTIRVRMGEYYEQYS--AYVFVRDA--- 502
              ++ L S        R  L      + D+G Y   V       +YS  A ++VR+    
Sbjct: 182  GRIKQLRSETFESTPIRGALQIESSEETDQGKYEC-VATNSAGVRYSSPANLYVRELREV 240

Query: 503  ----------DAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVG 552
                          E  P   +++ C+        + W Q                   G
Sbjct: 241  RRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQ-------------------G 281

Query: 553  TDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKAR 612
             +  +  +D PV      +T + +  +Y     A++ +G+            ++   +  
Sbjct: 282  AEDLTPEDDMPVGRNVLELTDVKDSANYT--CVAMSSLGV------------IEAVAQIT 327

Query: 613  LKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYF 672
            +KS P AP T                       VTE T + + ++W        + + Y+
Sbjct: 328  VKSLPKAPGTPM---------------------VTENTATSITITWDSGNP---DPVSYY 363

Query: 673  VEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV 732
            V + ++ +++      E  + + R+++  L+    Y   V   NS G G PSE+  VT  
Sbjct: 364  VIEYKSKSQDGPYQIKE-DITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESV-VTRT 421

Query: 733  GDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVG----YYIEASVAGSGKWEPCNN 788
            G++     AP  +     + T+++V WEE  +   L+     YY        G W+  N 
Sbjct: 422  GEQAPA-SAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHN- 479

Query: 789  NPVKGSRFTCHG-LVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPAL 847
              V  S  T  G L+  ++Y  RV A  + G       S+ I+VK   G    P    A 
Sbjct: 480  --VDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPL---SDPIQVKTQQGVPGQPMNLRAE 534

Query: 848  SDEPGGLTASRGRVHEASPP---TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQ 904
            +     +T S       SPP   +  K  LL  + +        + +G+T     +  V 
Sbjct: 535  ARSETSITLS------WSPPRQESIIKYELLFREGD------HGREVGRT-FDPTTSYVV 581

Query: 905  EELTPPPQKA------APQGKSKSDP-LKKKTDRAPPS-PPCDITCLESFRDSMVLGWK- 955
            E+L P  + A      +PQG     P ++++T ++ PS PP D+ C+     ++++ W+ 
Sbjct: 582  EDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRP 641

Query: 956  QPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMN 1015
             P +     + GY V YR +    P + +E N    +     +  L++   Y+    A  
Sbjct: 642  PPPETHNGALVGYSVRYRPLGSEDP-EPKEVNGIPPTTTQILLEALEKWTQYRITTVAHT 700

Query: 1016 MAGLGAPSAVSECFKCEEWTIAVP-GPPHSLKCSEVRKDSLVLQWKPPVHSGRT--PVTG 1072
              G G P +     + +E    VP  PP  ++   +   ++ + W+ P   GR    + G
Sbjct: 701  EVGPG-PESSPVVVRTDE---DVPSAPPRKVEAEALNATAIRVLWRSPA-PGRQHGQIRG 755

Query: 1073 YFVD--------------LKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAI 1118
            Y V               +K+    + QW   + A  + V   +  L+   +Y   V A 
Sbjct: 756  YQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMV---ITNLQPETAYSITVAAY 812

Query: 1119 NQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVST 1178
               G G  S     V      G   + V    +G +   +E    T + +    +     
Sbjct: 813  TMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGR 872

Query: 1179 EDSPRL 1184
            EDS  L
Sbjct: 873  EDSTPL 878



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 42/152 (27%), Positives = 59/152 (38%), Gaps = 15/152 (9%)

Query: 219 QSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPE 278
           +S   + A      EET + K   V       R S    L     Y  +L E   + AP 
Sbjct: 193 ESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANL-----YVRELREVRRV-APR 246

Query: 279 FIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLE 338
           F I P SH +    NV + C   G P P V W +    +           +   G + LE
Sbjct: 247 FSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPED-------DMPVGRNVLE 299

Query: 339 INGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
           +   D +D+A Y   AM+  G + A A + VK
Sbjct: 300 LT--DVKDSANYTCVAMSSLGVIEAVAQITVK 329



 Score = 35.8 bits (81), Expect = 0.36
 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 1/71 (1%)

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST-ADSGKYG 1645
            G   +  C   GDP P V+W K  K + S     ++F+    A   I  + T  D   Y 
Sbjct: 47   GGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYE 106

Query: 1646 LVVKNKYGSET 1656
             V +N  G  T
Sbjct: 107  CVAQNSVGEIT 117


>gi|157311649 neogenin homolog 1 [Homo sapiens]
          Length = 1461

 Score =  105 bits (261), Expect = 5e-22
 Identities = 189/877 (21%), Positives = 319/877 (36%), Gaps = 135/877 (15%)

Query: 292  ENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYR 351
            ++V L C  +G P P + W KN+  ++  ++    ++       +LEI+    +D   Y 
Sbjct: 264  QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG----SLEISDVTEDDAGTYF 319

Query: 352  ASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKF 411
              A N    + A A + V+                         P        I+  +  
Sbjct: 320  CIADNGNETIEAQAELTVQ-----------------------AQPEFLKQPTNIYAHESM 356

Query: 412  DVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH 471
            D+ F          C V   P      P ++W +NG  + PS + + +   +   L    
Sbjct: 357  DIVFE---------CEVTGKPT-----PTVKWVKNGDMVIPSDYFKIV---KEHNLQVLG 399

Query: 472  LNKEDEGLYTIRVRMGEYYEQYSAYVFVRD-ADAEIEGAPAAPLDVKCLEANKDYIIISW 530
            L K DEG Y           Q  A + + + A A     P+AP DV     +  +I ++W
Sbjct: 400  LVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTW 459

Query: 531  KQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKM 590
            + PA D     L Y +   + G       N +     +  +  L+    YIFRV A NK 
Sbjct: 460  RTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKH 519

Query: 591  GIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEAT 650
            G G                        SAP     +  E +P E  +PGP  +L    A+
Sbjct: 520  GSG----------------------ESSAP-----LRVETQP-EVQLPGPAPNLRAYAAS 551

Query: 651  RSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCF 710
             + + ++W+ P     E   Y +   E GT+  Q V+    V S  + +  L +   Y F
Sbjct: 552  PTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVD----VSSHSYTINGLKKYTEYSF 607

Query: 711  RVRCSNSAGVGEPSEATEVTVVGDKLDIPK-APGKIIPSRNTDTSVVVSWEESKDAK--- 766
            RV   N  G   P  +T    V    D+P  AP  +        S+++ W+    A    
Sbjct: 608  RVVAYNKHG---PGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNG 664

Query: 767  ELVGYYIEASVAGSGKWEPCNNNPVKGSRFT--CHGLVTGQSYIFRVRAVNAAGLSEYSQ 824
            ++ GY I    A   +        V G++ +    GL  G  Y FRV A+   G    + 
Sbjct: 665  QITGYKIRYRKA--SRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATD 722

Query: 825  DSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLG-------S 877
               A   ++ +     P+V  +L   P  L  S   V   +PP  Q   + G        
Sbjct: 723  WLSAETFESDLDETRVPEVPSSLHVRP--LVTS--IVVSWTPPENQNIVVRGYAIGYGIG 778

Query: 878  KPNKPSL---------------PSSSQNLGQTEVSKVSETV---QEELTPPPQKAAPQGK 919
             P+  ++               PSS   +     + V E +   +  +T P    +    
Sbjct: 779  SPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDL 838

Query: 920  SK-SDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITG--YYVNYREVI 976
               + P     D  P  PP  +       D++ + W         +IT   YY    +  
Sbjct: 839  FVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTN 898

Query: 977  DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAV-SECFKCEEWT 1035
                 K++ AN   +S   Y ++ LK N +Y+F V    M   G  S+  S       + 
Sbjct: 899  IPANTKYKNANATTLS---YLVTGLKPNTLYEFSV----MVTKGRRSSTWSMTAHGTTFE 951

Query: 1036 IAVPGPPH--SLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLK-EAKAKEDQWRGLNE 1092
            +    PP   ++   E +  ++++ W+PP       +TGY +    +  A+   W  + E
Sbjct: 952  LVPTSPPKDVTVVSKEGKPKTIIVNWQPP-SEANGKITGYIIYYSTDVNAEIHDW--VIE 1008

Query: 1093 AAIKN-VYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              + N +  +++ L     Y F+++A N  G+G  S+
Sbjct: 1009 PVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSE 1045



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 180/801 (22%), Positives = 295/801 (36%), Gaps = 151/801 (18%)

Query: 277  PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY---- 332
            PEF+ +P +    E  ++   C + G P P V W KN          G  +I S Y    
Sbjct: 341  PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKN----------GDMVIPSDYFKIV 390

Query: 333  GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF 392
              H L++ G    D   Y+  A N  G   A A +++            HA A+T PL  
Sbjct: 391  KEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILE----------HAPATTGPLPS 440

Query: 393  G---VTPYGYASRF----------EIHFDD-KFDVSFGREGETMSLGCRVVITPEIKHFQ 438
                V     ++RF          + H D+  + V + +EG       RV  T      Q
Sbjct: 441  APRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARE---RVENTSHPGEMQ 497

Query: 439  PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHL---NKEDEGLYTIRVRMGEYYEQYSA 495
              IQ   N +P               AT+    +   NK   G  +  +R+         
Sbjct: 498  VTIQ---NLMP---------------ATVYIFRVMAQNKHGSGESSAPLRV--------- 530

Query: 496  YVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDS 555
                 +   E++    AP +++   A+   I ++W+ P V G   I  Y +   E GTD 
Sbjct: 531  -----ETQPEVQLPGPAP-NLRAYAASPTSITVTWETP-VSGNGEIQNYKLYYMEKGTD- 582

Query: 556  WSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKS 615
              +  D  V    + + GL +   Y FRV A NK G G    VS P  A+       L  
Sbjct: 583  --KEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPG----VSTPDVAV-----RTLSD 631

Query: 616  RPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM--YFV 673
             PSA                     P +LS+       +++ W+PP      G +  Y +
Sbjct: 632  VPSA--------------------APQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKI 671

Query: 674  EKCEAGTENWQRVNTELPVKSPRFA--LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTV 731
               +A  ++     TE  V   + +  +  L  G  Y FRV      G G  ++      
Sbjct: 672  RYRKASRKS---DVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAET 728

Query: 732  VGDKLD---IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNN 788
                LD   +P+ P   +  R   TS+VVSW   ++   +V  Y      GS   +    
Sbjct: 729  FESDLDETRVPEVPSS-LHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKV 787

Query: 789  NPVKGSRFTCHGLVTGQSYIFRVRAVNAAG---------LSEYSQDSEAIEVKAAIGGGV 839
            +  K   +T   L     Y+  ++A N  G         ++    D+  +++   I    
Sbjct: 788  D-YKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDL-FVINAPY 845

Query: 840  SPDVCPALSDEPGGLTAS-------RGRVHEASPPTFQK--DALLGSKPNKPSLPSSS-- 888
            +P   P     P G+ AS       R    + S P  QK  D+   +   K ++P+++  
Sbjct: 846  TPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKY 905

Query: 889  QNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKS----DPLKKKTDRAPPSPPCDITCL- 943
            +N   T +S +   ++            +G+  S           +  P SPP D+T + 
Sbjct: 906  KNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVS 965

Query: 944  -ESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLK 1002
             E    ++++ W+ P +  G +ITGY + Y   ++     W    V   +   ++I  L 
Sbjct: 966  KEGKPKTIIVNWQPPSEANG-KITGYIIYYSTDVNAEIHDWVIEPVVG-NRLTHQIQELT 1023

Query: 1003 ENMVYQFQVAAMNMAGLGAPS 1023
             +  Y F++ A N  G+G  S
Sbjct: 1024 LDTPYYFKIQARNSKGMGPMS 1044



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 60/291 (20%), Positives = 118/291 (40%), Gaps = 49/291 (16%)

Query: 1373 NVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKD 1432
            N +L C+V N      + W ++ + + +D++   K     L+I+  ++ D G+Y  +++ 
Sbjct: 168  NAILNCEV-NADLVPFVRWEQNRQPLLLDDRV-IKLPSGMLVISNATEGDGGLYRCVVES 225

Query: 1433 D---RGKDKSRLKLVD--EAFKELMM--EVCKKIALSATDLKIQSTAEGIQLYSFVTYYV 1485
                +  D+  LK++   E   +L+   +    + +   D+ +   A G+   +      
Sbjct: 226  GGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPT------ 279

Query: 1486 EDLKVNWSHNGSAI--RYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKT 1543
                + W  N  A+    S+R+     G    L+I++ T +D G Y     +G     +T
Sbjct: 280  ----IKWMKNEEALDTESSERLVLLAGGS---LEISDVTEDDAGTYFCIADNGN----ET 328

Query: 1544 VDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPE 1603
            ++   +   +A  EF  LKQ               P  +   E   +   C V G P P 
Sbjct: 329  IEAQAELTVQAQPEF--LKQ---------------PTNIYAHESMDIVFECEVTGKPTPT 371

Query: 1604 VSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGS 1654
            V W+KN   +   D+    F+  +     + G+  +D G Y  + +N  G+
Sbjct: 372  VKWVKNGDMVIPSDY----FKIVKEHNLQVLGLVKSDEGFYQCIAENDVGN 418



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 76/293 (25%), Positives = 116/293 (39%), Gaps = 42/293 (14%)

Query: 1373 NVLLKCKVANIKKETHIVWYKDE---REISVDEKHDFKDG---ICTLLITEFSKKDAGIY 1426
            +V+L C  A  +    I W KD      +S D +    DG   I  ++ ++ +K D G Y
Sbjct: 69   SVILNCS-AYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYY 127

Query: 1427 EVILK-DDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYV 1485
            + +   +  G   SR   +  A         +  ++ A +  I +      L  FV    
Sbjct: 128  QCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNADLVPFV---- 183

Query: 1486 EDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY--VMELFDGKTGHQKT 1543
                  W  N   +   DRV    +G    L I+  T  D G Y  V+E   G   +   
Sbjct: 184  -----RWEQNRQPLLLDDRVIKLPSG---MLVISNATEGDGGLYRCVVES-GGPPKYSDE 234

Query: 1544 VDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPE 1603
            V+L      E  ++   LKQ +       RV+G   DVV         L C   G P P 
Sbjct: 235  VELKVLPDPEVISDLVFLKQPSPL----VRVIG--QDVV---------LPCVASGLPTPT 279

Query: 1604 VSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSET 1656
            + W+KNE+AL ++    L   AG +    I+ V+  D+G Y  +  N  G+ET
Sbjct: 280  IKWMKNEEALDTESSERLVLLAGGS--LEISDVTEDDAGTYFCIADN--GNET 328



 Score = 38.1 bits (87), Expect = 0.073
 Identities = 32/123 (26%), Positives = 56/123 (45%), Gaps = 16/123 (13%)

Query: 614  KSRPSAPWTGQIIVTEEEPSEGIVP-GPPTDLSVT--EATRSYVVLSWKPPGQRGHE--- 667
            K R S+ W+    +T    +  +VP  PP D++V   E     ++++W+PP +   +   
Sbjct: 934  KGRRSSTWS----MTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITG 989

Query: 668  GIMYFVEKCEAGTENWQRVNTELPVKSPRFA--LFDLAEGKSYCFRVRCSNSAGVGEPSE 725
             I+Y+     A   +W       PV   R    + +L     Y F+++  NS G+G  SE
Sbjct: 990  YIIYYSTDVNAEIHDW----VIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSE 1045

Query: 726  ATE 728
            A +
Sbjct: 1046 AVQ 1048



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
            P+  ++  G    L C V  D  P V W +N + L  DD   +K  +G      I+  + 
Sbjct: 158  PEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRV-IKLPSG---MLVISNATE 213

Query: 1639 ADSGKYGLVVKNKYGSETSDFTVSVFIPEEE 1669
             D G Y  VV++    + SD      +P+ E
Sbjct: 214  GDGGLYRCVVESGGPPKYSDEVELKVLPDPE 244


>gi|46049119 myosin binding protein C, slow type isoform 3 [Homo
           sapiens]
          Length = 1141

 Score =  105 bits (261), Expect = 5e-22
 Identities = 85/322 (26%), Positives = 133/322 (41%), Gaps = 58/322 (18%)

Query: 439 PEIQWYRNGVPLSP-SKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
           P+  W R    +   S  ++T    + +TL      ++D G+Y I ++     E   A+ 
Sbjct: 555 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN----EAGEAHA 610

Query: 498 FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
            ++    +    P AP      E   D+ I++W+ PA DGGSPILGYFI++ +  +  W 
Sbjct: 611 SIKVKVVDFPDPPVAPT---VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 667

Query: 558 QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRP 617
           + N    K   F    +IEG +Y  R+ AVN +GI  PS  S P   L            
Sbjct: 668 RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPL------------ 715

Query: 618 SAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKC 676
                              V  PPT L+V   T + V + W+PP   G  G+  Y +E C
Sbjct: 716 ------------------AVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757

Query: 677 EAGT------------------ENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSA 718
             G+                  E+W   N +L +   +F +  L        RV+  N+A
Sbjct: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAA 816

Query: 719 GVGEPSEATEVTVVGDKLDIPK 740
           G  EP   ++  +V + ++ PK
Sbjct: 817 GASEPKYYSQPILVKEIIEPPK 838



 Score =  104 bits (259), Expect = 8e-22
 Identities = 181/777 (23%), Positives = 287/777 (36%), Gaps = 143/777 (18%)

Query: 287  TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
            T +  E V+L C ++   +  V W+KN   I +     +Y I      H L I G    D
Sbjct: 352  TAYCGERVELECEVSE-DDANVKWFKNGEEI-IPGPKSRYRIRVEGKKHILIIEGATKAD 409

Query: 347  TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
             A+Y  S M   G+ SA  SV +K                  PL   +TP          
Sbjct: 410  AAEY--SVMTTGGQSSAKLSVDLK------------------PLKI-LTPL--------- 439

Query: 407  FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
                         +T++LG  + +  EI    P  +W +NG+P+  S  ++ +  G    
Sbjct: 440  -----------TDQTVNLGKEICLKCEISENIPG-KWTKNGLPVQESDRLKVVHKGRIHK 487

Query: 467  LTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYI 526
            L  ++   EDEG         +Y     AY     A   +   P   LD   L+A+    
Sbjct: 488  LVIANALTEDEG---------DYVFAPDAYNVTLPAKVHVIDPPKIILDG--LDADNTVT 536

Query: 527  IISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRA 586
            +I+  +  ++   PI G    K       WS+ +      A    +G I   SY      
Sbjct: 537  VIAGNKLRLE--IPISGEPPPKA-----MWSRGDK-----AIMEGSGRIRTESYPDSSTL 584

Query: 587  VNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSV 646
            V    I    R    V  ++   +A       A  + ++ V +        P PP   +V
Sbjct: 585  V----IDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVD-------FPDPPVAPTV 628

Query: 647  TEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEG 705
            TE    + +++W+PP   G   I+ YF+E+ +  +  W R+N +L  K   F    + EG
Sbjct: 629  TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEG 687

Query: 706  KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESK 763
             +Y  R+   N+ G+ +PS  +   V    L +   P  +     TDT+V + W   +  
Sbjct: 688  VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744

Query: 764  DAKELVGYYIEASVAGSGK------------------WEPCNNNPVKGSRFTCHGLVTGQ 805
             A  L GY +E    GS                    W   N + +  ++FT  GL T  
Sbjct: 745  GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804

Query: 806  SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEAS 865
                RV+AVNAAG SE    S+ I VK  I              EP  +   R       
Sbjct: 805  KIFVRVKAVNAAGASEPKYYSQPILVKEII--------------EPPKIRIPRHLKQTYI 850

Query: 866  PPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPP---PQKAAPQGKSKS 922
                +   L+     KP  P  +      E+ K    ++   T      +KA      K 
Sbjct: 851  RRVGEAVNLVIPFQGKPR-PELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKY 909

Query: 923  DPLKKKTDR------------APPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYV 970
            D L+ K D+              P PP  +   + + +++ L W  P   G A ITGY +
Sbjct: 910  D-LQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTI 968

Query: 971  NYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
               +  D    +W    ++     +  I+ L     Y F+V + NM GL   + +++
Sbjct: 969  ---QKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 120/552 (21%), Positives = 205/552 (37%), Gaps = 79/552 (14%)

Query: 934  PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
            P PP   T  E   D  ++ W+ P   GG+ I GY++  ++       +W   N     E
Sbjct: 620  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS---RWMRLNFDLCKE 676

Query: 994  EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
              ++   + E + Y+ ++ A+N  G+  PS  S  F      +AV  PP  L    V   
Sbjct: 677  TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTVDSVTDT 732

Query: 1054 SLVLQWKPPVHSGRTPVTGYFVDL---KEAKAKE-------------DQWRGLNEAAIKN 1097
            ++ ++W+PP H G   + GY ++        AK+             + W   N+  I  
Sbjct: 733  TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDK 792

Query: 1098 VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE----------TRPGTKEVVVN 1147
                + GL        RV+A+N AG  +P   + P++ +           R   +  +  
Sbjct: 793  TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 852

Query: 1148 VDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGI 1207
            V +   + + F+     P+ E +W KD     D  ++ + +    T +  +       G 
Sbjct: 853  VGEAVNLVIPFQ---GKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGK 908

Query: 1208 YSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAE 1267
            Y   V   D    +  ID + + R          P  P    + +E +    V       
Sbjct: 909  YDLQV-KVDKFVETASIDIQIIDR----------PGPP--QIVKIEDVWGENVALTWTPP 955

Query: 1268 KLSGNAKV-NYIFN--EKEIFEGPKYKMHIDRNTGII-------EMFMEKLQDEDEGTYT 1317
            K  GNA +  Y     +K+  E      H  R +  I       E +     +   G   
Sbjct: 956  KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL-- 1013

Query: 1318 FQLQDGKATNHSTVVL-VGDVFKK-LQKEAEFQRQEWIRKQGPHFVEYL--SWEVTGECN 1373
               +D   T  S V+   G ++K  + ++ +F        + P F + L  ++ + G  N
Sbjct: 1014 --SEDATMTKESAVIARDGKIYKNPVYEDFDF-------SEAPMFTQPLVNTYAIAG-YN 1063

Query: 1374 VLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIYEVILK 1431
              L C V    K   I W K++  I  D ++      G+CTL I + S  D G Y     
Sbjct: 1064 ATLNCSVRGNPK-PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAV 1122

Query: 1432 DDRGKDKSRLKL 1443
            +D G  +   KL
Sbjct: 1123 NDLGTVEIECKL 1134



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 105/445 (23%), Positives = 169/445 (37%), Gaps = 76/445 (17%)

Query: 1229 LKRLLALSHEHKFPTVPVKS-ELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEG 1287
            LKRL  +  E K      K  + A ++ + G+VRF +  E      +V +  N +EI   
Sbjct: 238  LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 295

Query: 1288 PKYKMHIDRNTGIIE-MFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAE 1346
             KY   I  + G    +F+   Q  D+  Y     D K    ST + V +    + K+ E
Sbjct: 296  TKY---IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC---STELFVREPPIMVTKQLE 349

Query: 1347 FQRQEWIRKQGPHFVEYLSWEVTGECN--VLLKCKVANIKKETHIVWYKDEREISVDEKH 1404
                                + T  C   V L+C+V+  + + ++ W+K+  EI    K 
Sbjct: 350  --------------------DTTAYCGERVELECEVS--EDDANVKWFKNGEEIIPGPKS 387

Query: 1405 DFK---DGICTLLITE-FSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIA 1460
             ++   +G   +LI E  +K DA  Y V+    +   K  + L     K L      KI 
Sbjct: 388  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-----KPL------KIL 436

Query: 1461 LSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINE 1520
               TD  +    E I L   ++   E++   W+ NG  ++ SDR+K    G    L I  
Sbjct: 437  TPLTDQTVNLGKE-ICLKCEIS---ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 492

Query: 1521 PTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGL-- 1578
                D+G YV         +  T+       D                     +L GL  
Sbjct: 493  ALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKI-----------------ILDGLDA 531

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
             + VT+  G  L L   + G+PPP+  W + +KA+              ++   I+    
Sbjct: 532  DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAER 591

Query: 1639 ADSGKYGLVVKNKYGSETSDFTVSV 1663
             DSG Y + +KN+ G   +   V V
Sbjct: 592  DDSGVYHINLKNEAGEAHASIKVKV 616



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 38/169 (22%), Positives = 76/169 (44%), Gaps = 11/169 (6%)

Query: 438  QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAY 496
            +PE+ W ++G  +  ++    + + E  T+ F     +   G Y ++V++ ++ E  S  
Sbjct: 868  RPELTWKKDGAEIDKNQI--NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI- 924

Query: 497  VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
                  D +I   P  P  VK  +   + + ++W  P  DG + I GY I K +  +  W
Sbjct: 925  ------DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 978

Query: 557  SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAAL 605
                +   + +   +T L+ G  Y FRV + N  G+   + +++  A +
Sbjct: 979  FTVIEHYHRTSA-TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1026



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 293  NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352
            N  L+CS+ G P+P++TW KN+V I    +  +Y + S  G+ TLEI      D   Y  
Sbjct: 1063 NATLNCSVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119

Query: 353  SAMNVKGELSAYASVVVK 370
             A+N  G +     + VK
Sbjct: 1120 KAVNDLGTVEIECKLEVK 1137



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 638  PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
            PGPP  + + +     V L+W PP   G+  I  Y ++K +  +  W  V       S  
Sbjct: 932  PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA- 990

Query: 697  FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV 732
              + +L  G  Y FRV   N  G+ E +  T+ + V
Sbjct: 991  -TITELVIGNEYYFRVFSENMCGLSEDATMTKESAV 1025



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 35/139 (25%), Positives = 62/139 (44%), Gaps = 4/139 (2%)

Query: 1542 KTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPP 1601
            K V+ +G +  + Y++   +K+  I E  + R+   L      + G+A+NL     G P 
Sbjct: 811  KAVNAAGASEPKYYSQPILVKE--IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 868

Query: 1602 PEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTV 1661
            PE++W K + A    +  N++     T  F I     + SGKY L VK     ET+   +
Sbjct: 869  PELTW-KKDGAEIDKNQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDI 926

Query: 1662 SVFIPEEEARMAALESLKG 1680
             +       ++  +E + G
Sbjct: 927  QIIDRPGPPQIVKIEDVWG 945



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 38/147 (25%), Positives = 61/147 (41%), Gaps = 17/147 (11%)

Query: 237 EKKSRKVVIREKAERLSLRKTLEETE--------TYHAKLNED-HLLHAPEFIIK----P 283
           E    KVV + +  +L +   L E E         Y+  L    H++  P+ I+      
Sbjct: 473 ESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDAD 532

Query: 284 RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
            + TV     ++L   I+G P P+  W +    I      G+   ES     TL I+  +
Sbjct: 533 NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI--MEGSGRIRTESYPDSSTLVIDIAE 590

Query: 344 FEDTAQYRASAMNVKGELSAYASVVVK 370
            +D+  Y  +  N  GE  A+AS+ VK
Sbjct: 591 RDDSGVYHINLKNEAGE--AHASIKVK 615



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
            G    L C+V G+P P+++W+KN+ A+  D    + F         I   S  D G Y  
Sbjct: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCC 1119

Query: 1647 VVKNKYGS 1654
               N  G+
Sbjct: 1120 KAVNDLGT 1127


>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
          Length = 1447

 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 180/887 (20%), Positives = 304/887 (34%), Gaps = 130/887 (14%)

Query: 279  FIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLE 338
            F+ +P +    E ++  L C ++G+P P  TW + +  I + +   KY   S  G   L 
Sbjct: 242  FLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSK--KY---SLLGGSNLL 296

Query: 339  INGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYG 398
            I+    +D+  Y          +SA A + V                        V P+ 
Sbjct: 297  ISNVTDDDSGMYTCVVTYKNENISASAELTVL-----------------------VPPWF 333

Query: 399  YASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQT 458
                  ++  +  D+ F          C V   P      P + W +NG  + PS + Q 
Sbjct: 334  LNHPSNLYAYESMDIEFE---------CTVSGKPV-----PTVNWMKNGDVVIPSDYFQI 379

Query: 459  LWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFV-RDADAEIEGAPAAPLDVK 517
            +     + L    + K DEG Y           Q SA + V + A       P+AP DV 
Sbjct: 380  VGG---SNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVV 436

Query: 518  CLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEG 577
             +  +  ++ +SW+ PA   G+ I  + +     G +     N T     +  V  L   
Sbjct: 437  PVLVSSRFVRLSWRPPAEAKGN-IQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPE 495

Query: 578  RSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIV 637
              Y FRV A N+ G   P   S+P+                       + T+ E     V
Sbjct: 496  AMYTFRVVAYNEWG---PGESSQPIK----------------------VATQPELQ---V 527

Query: 638  PGPPTDLSVTEATRSYVVLSWKPPGQRGH--EGIMYFVEKCEAGTENWQRVNTELPVKSP 695
            PGP  +L     + + ++++W+PP       +G   F  +   G E        + V   
Sbjct: 528  PGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLFCTEVSTGKEQ------NIEVDGL 581

Query: 696  RFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDT-S 754
             + L  L +   Y  R    N  G G  ++  ++TVV    D+P AP + +     ++ S
Sbjct: 582  SYKLEGLKKFTEYSLRFLAYNRYGPGVSTD--DITVV-TLSDVPSAPPQNVSLEVVNSRS 638

Query: 755  VVVSWEESKDAKE---LVGYYI-EASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFR 810
            + VSW       +   + GY I        G+ E    N +    +   GL  G  Y F+
Sbjct: 639  IKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNL---WYLFTGLEKGSQYSFQ 695

Query: 811  VRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQ 870
            V A+   G    S    A   +  +     PD   +L   P             +P    
Sbjct: 696  VSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCIIMSWTPPLNPNIVV 755

Query: 871  KDALLGSKPNKP-----------------SLPSSSQ--------NLGQTEVSKVSETVQE 905
            +  ++G     P                  L SSS         N     V         
Sbjct: 756  RGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTR 815

Query: 906  ELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQ---PDKIGG 962
             +T P             P        P  PP  +  +    D++ + W     P     
Sbjct: 816  SITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKT 875

Query: 963  AEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
            +E+  Y V +R        K++  +  ++S   Y  + LK N +Y+F V           
Sbjct: 876  SEVRLYTVRWRTSF-SASAKYKSEDTTSLS---YTATGLKPNTMYEFSVMVTKNRRSSTW 931

Query: 1023 SAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLK-EAK 1081
            S  +     E    + P    ++   E +  ++++ W+PP+ +    +T Y +    +  
Sbjct: 932  SMTAHATTYEAAPTSAP-KDLTVITREGKPRAVIVSWQPPLEA-NGKITAYILFYTLDKN 989

Query: 1082 AKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
               D W  +   +   +  ++  L     Y FR++A N  GVG  SD
Sbjct: 990  IPIDDWI-METISGDRLTHQIMDLNLDTMYYFRIQARNSKGVGPLSD 1035



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 155/766 (20%), Positives = 258/766 (33%), Gaps = 122/766 (15%)

Query: 279  FIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLE 338
            F+ +  S T +  + V L C + G P P + W KNQ  +       + ++        L+
Sbjct: 142  FLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVV---LPSGALQ 198

Query: 339  INGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYG 398
            I+     D   YR SA N     +           G   E R  +               
Sbjct: 199  ISRLQPGDIGIYRCSARNPASSRT-----------GNEAEVRILSDPGL----------- 236

Query: 399  YASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQT 458
                 +++F  +       EG+   L C V   P      P   W R    +       +
Sbjct: 237  ---HRQLYFLQRPSNVVAIEGKDAVLECCVSGYP-----PPSFTWLRGEEVIQLRSKKYS 288

Query: 459  LWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFV------RDADAEIEGAPAA 512
            L  G  + L  S++  +D G+YT  V         SA + V       +  + +    + 
Sbjct: 289  LLGG--SNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESM 346

Query: 513  PLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVT 572
             ++ +C  + K                           V T +W +  D  +    F + 
Sbjct: 347  DIEFECTVSGK--------------------------PVPTVNWMKNGDVVIPSDYFQIV 380

Query: 573  GLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEE- 631
            G         R+  V K   GF   V+E  A              +A  + Q+IV +   
Sbjct: 381  G-----GSNLRILGVVKSDEGFYQCVAENEAG-------------NAQTSAQLIVPKPAI 422

Query: 632  PSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELP 691
            PS  ++P  P D+     +  +V LSW+PP +       + V     G    + +NT  P
Sbjct: 423  PSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQP 482

Query: 692  VKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNT 751
              S +  + +L     Y FRV   N  G GE S+  +V     +L +P     +     +
Sbjct: 483  -GSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKV-ATQPELQVPGPVENLQAVSTS 540

Query: 752  DTSVVVSWEESKDAKELV-GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFR 810
             TS++++WE    A   V GY +  +   +GK +   N  V G  +   GL     Y  R
Sbjct: 541  PTSILITWEPPAYANGPVQGYRLFCTEVSTGKEQ---NIEVDGLSYKLEGLKKFTEYSLR 597

Query: 811  VRAVNAAGLSEYSQDSEAI---EVKAAIGGGVSPDVC-----------PALSDEPGGLTA 856
              A N  G    + D   +   +V +A    VS +V            P    + G +T 
Sbjct: 598  FLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITG 657

Query: 857  SRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAP 916
             + R  +    T ++  +   +PN      +    G     +VS        PP      
Sbjct: 658  YKIRHRK----TTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPP-----S 708

Query: 917  QGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVI 976
               +   P     +   P  P  +  +    + +++ W  P       + GY + Y    
Sbjct: 709  NWYTAETPENDLDESQVPDQPSSLH-VRPQTNCIIMSWTPPLN-PNIVVRGYIIGY---- 762

Query: 977  DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
             GV   + E       +  Y I  L+ +  Y   + A N AG G P
Sbjct: 763  -GVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVP 807



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 162/800 (20%), Positives = 276/800 (34%), Gaps = 147/800 (18%)

Query: 273  LLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY 332
            +L  P F+  P +   +E  +++  C+++G P P V W KN          G  +I S Y
Sbjct: 327  VLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKN----------GDVVIPSDY 376

Query: 333  ----GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTM 388
                G   L I G    D   Y+  A N  G     A ++V +             +S +
Sbjct: 377  FQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPK--------PAIPSSSVL 428

Query: 389  PLS-FGVTPYGYASRFEIHFD-----------DKFDVSFGREGETMSLGCRVVITPEIKH 436
            P +   V P   +SRF +                F V F REG+                
Sbjct: 429  PSAPRDVVPVLVSSRF-VRLSWRPPAEAKGNIQTFTVFFSREGDNRE------------- 474

Query: 437  FQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIR-VRMGEYYEQYSA 495
                                + L + +  +L  +  N + E +YT R V   E+    S+
Sbjct: 475  --------------------RALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESS 514

Query: 496  YVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDS 555
                     E++  P    +++ +  +   I+I+W+ PA   G P+ GY +   EV T  
Sbjct: 515  QPIKVATQPELQ-VPGPVENLQAVSTSPTSILITWEPPAYANG-PVQGYRLFCTEVST-- 570

Query: 556  WSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKS 615
              +  +  V    + + GL +   Y  R  A N+ G         P  + D      L  
Sbjct: 571  -GKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYG---------PGVSTDDITVVTLSD 620

Query: 616  RPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEK 675
             PSA                    PP ++S+       + +SW PP      G +   + 
Sbjct: 621  VPSA--------------------PPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKI 660

Query: 676  CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
                T     + T L   +  +    L +G  Y F+V      G G PS         + 
Sbjct: 661  RHRKTTRRGEMET-LEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPEND 719

Query: 736  LD---IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVK 792
            LD   +P  P  +     T+  +++SW    +   +V  YI     GS   E    +  K
Sbjct: 720  LDESQVPDQPSSLHVRPQTN-CIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDS-K 777

Query: 793  GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPG 852
               ++   L +   Y+  ++A N AG  E     E+   ++        D  P L D P 
Sbjct: 778  QRYYSIERLESSSHYVISLKAFNNAG--EGVPLYESATTRSITDPTDPVDYYPLLDDFPT 835

Query: 853  GL------------TASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVS 900
             +              +    H+A   ++  +++   K  K S         +T  S  +
Sbjct: 836  SVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSV--PKNQKTSEVRLYTVRWRTSFSASA 893

Query: 901  ETVQEELTPPPQKAA---PQGKSKSDPLKKKTDR---------------APPSPPCDITC 942
            +   E+ T     A    P    +   +  K  R               AP S P D+T 
Sbjct: 894  KYKSEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTV 953

Query: 943  L--ESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISN 1000
            +  E    ++++ W+ P +  G +IT Y + Y    +     W    +       ++I +
Sbjct: 954  ITREGKPRAVIVSWQPPLEANG-KITAYILFYTLDKNIPIDDWIMETISG-DRLTHQIMD 1011

Query: 1001 LKENMVYQFQVAAMNMAGLG 1020
            L  + +Y F++ A N  G+G
Sbjct: 1012 LNLDTMYYFRIQARNSKGVG 1031



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 77/310 (24%), Positives = 114/310 (36%), Gaps = 55/310 (17%)

Query: 1373 NVLLKCKVANIKKETHIVWYKDEREISV---DEKHDFKDG---ICTLLITEFSKKDAGIY 1426
            NVLL C   + +    I W KD   +++   + K    +G   I  +L +   K D G+Y
Sbjct: 56   NVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLY 115

Query: 1427 EVILK-DDRGKDKSRLKLVDEAFKELMMEVCKKIALSATD---LKIQSTAEGIQLYSFVT 1482
            +      D G   SR   V  A     +   + +     D   LK +   E +       
Sbjct: 116  QCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPT----- 170

Query: 1483 YYVEDLKVNWSHNG---SAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKY---VMELFDG 1536
                   ++W  N    + I    RV    +G    LQI+   P D G Y          
Sbjct: 171  -------IHWQKNQQDLTPIPGDSRVVVLPSGA---LQISRLQPGDIGIYRCSARNPASS 220

Query: 1537 KTGHQKTVD-LSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCN 1595
            +TG++  V  LS           QR                  P  V   EGK   L C 
Sbjct: 221  RTGNEAEVRILSDPGLHRQLYFLQR------------------PSNVVAIEGKDAVLECC 262

Query: 1596 VWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVV--KNKYG 1653
            V G PPP  +WL+ E+ +      + K+     +   I+ V+  DSG Y  VV  KN+  
Sbjct: 263  VSGYPPPSFTWLRGEEVIQLR---SKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENI 319

Query: 1654 SETSDFTVSV 1663
            S +++ TV V
Sbjct: 320  SASAELTVLV 329



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 4/76 (5%)

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVST 1638
            P  +   E   +   C V G P P V+W+KN   +   D+    F+    +   I GV  
Sbjct: 337  PSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDY----FQIVGGSNLRILGVVK 392

Query: 1639 ADSGKYGLVVKNKYGS 1654
            +D G Y  V +N+ G+
Sbjct: 393  SDEGFYQCVAENEAGN 408


>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
           ROBO2a [Homo sapiens]
          Length = 1394

 Score = 95.5 bits (236), Expect = 4e-19
 Identities = 118/502 (23%), Positives = 183/502 (36%), Gaps = 72/502 (14%)

Query: 277 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYK----NQVPINVHANPGKYIIESRY 332
           P+F+++PR   V +   V   C   G P+P V W K    N +  N    P      S  
Sbjct: 330 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 389

Query: 333 GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF 392
           G   L I      D   Y   A+ V G + A A + V     +        G +   L+ 
Sbjct: 390 G--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAV 447

Query: 393 GVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPL-- 450
             T                            L C+    P      P I W + G     
Sbjct: 448 DGTAL--------------------------LKCKATGDP-----LPVISWLKEGFTFPG 476

Query: 451 -SPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADA----- 504
             P   +Q     E+ TL   +L   D G YT           +SA + V ++ A     
Sbjct: 477 RDPRATIQ-----EQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKN 531

Query: 505 -EIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTP 563
            ++   P  P   +  +  K+ + +SW QP   G  P   Y I+       +  Q     
Sbjct: 532 YDLSDLPGPPSKPQVTDVTKNSVTLSW-QPGTPGTLPASAYIIEAFSQSVSNSWQTVANH 590

Query: 564 VKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKAR-LKSRPSAPWT 622
           VK   + V GL     Y+F VRA+N  G+  PS +S+PV   D +  A+ +  R      
Sbjct: 591 VKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKEL 650

Query: 623 GQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTEN 682
           G ++V    P    V   PT + VT        +  +P   +G+  +MY        T +
Sbjct: 651 GDVLVRLHNP----VVLTPTTVQVT------WTVDRQPQFIQGYR-VMYRQTSGLQATSS 699

Query: 683 WQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAP 742
           WQ ++ ++P +     L +L +G +Y  +VR   +   G  SE+  V       + P AP
Sbjct: 700 WQNLDAKVPTERSA-VLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTE---EAPSAP 755

Query: 743 GKIIP----SRNTDTSVVVSWE 760
            + +          TS+ VSW+
Sbjct: 756 PQSVTVLTVGSYNSTSISVSWD 777



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 1038 VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
            +PGPP   + ++V K+S+ L W+P    G  P + Y ++   +++  + W+ +    +K 
Sbjct: 537  LPGPPSKPQVTDVTKNSVTLSWQPGT-PGTLPASAYIIEAF-SQSVSNSWQTVANH-VKT 593

Query: 1098 VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPV 1133
                VRGL+    Y+F VRAIN  G+  PS ++ PV
Sbjct: 594  TLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPV 629



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 88/340 (25%), Positives = 133/340 (39%), Gaps = 35/340 (10%)

Query: 715  SNSAGVGEPSEATEVTVVG-------DKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAK- 766
            ++S+G    S   +VT  G       D  D+P  P K   +  T  SV +SW+       
Sbjct: 507  TSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTL 566

Query: 767  ELVGYYIEA-SVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQD 825
                Y IEA S + S  W+   N+ VK + +T  GL     Y+F VRA+N  GLS+ S  
Sbjct: 567  PASAYIIEAFSQSVSNSWQTVANH-VKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPM 625

Query: 826  SEAI---EVKAAIGGGVSPDVCPALSD------EPGGLTASRGRVH---EASPPTFQKDA 873
            S+ +   ++     G     V   L D       P  LT +  +V    +  P   Q   
Sbjct: 626  SDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYR 685

Query: 874  LLGSKPNKPSLPSSSQNLG---QTEVSKV----SETVQEELTPPPQKAAPQGKSKSDPLK 926
            ++  + +     SS QNL     TE S V     + V  E+   P     QG        
Sbjct: 686  VMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTV 745

Query: 927  KKTDRAPPSPPCDITCLE--SFRD-SMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKW 983
            + T+ AP +PP  +T L   S+   S+ + W  P         G    Y+    G   ++
Sbjct: 746  RTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPP---DHQNGIIQEYKIWCLGNETRF 802

Query: 984  REANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPS 1023
                    +  +  I  L   + Y+ +VAA   AG+G  S
Sbjct: 803  HINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS 842



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 62/275 (22%), Positives = 96/275 (34%), Gaps = 74/275 (26%)

Query: 233 EETSEKKSRKVVIREKAERLSLR----------------------KTLEETETYHAKLNE 270
           E T   K  KV I +K ER+S+R                        + E ++  A+L  
Sbjct: 178 EPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELT- 236

Query: 271 DHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIES 330
             +   P F+ +P +  V E+E V+  C + G P+P V W K+   +      G+Y I+ 
Sbjct: 237 --VFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADL----PRGRYDIKD 290

Query: 331 RYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
            Y   TL I      D   Y   A N  G++ A A++ V+                  P 
Sbjct: 291 DY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVR-----------------APP 330

Query: 391 SFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNG--- 447
            F V P                     +G T++  C     P     QP + W + G   
Sbjct: 331 QFVVRPRD---------------QIVAQGRTVTFPCETKGNP-----QPAVFWQKEGSQN 370

Query: 448 --VPLSPSKWVQTLWSGERATLTFSHLNKEDEGLY 480
              P  P +            LT +++ + D G Y
Sbjct: 371 LLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYY 405



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 53/229 (23%), Positives = 83/229 (36%), Gaps = 19/229 (8%)

Query: 934  PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
            P PP      +  ++S+ L W QP   G    + Y +        V   W+      V  
Sbjct: 538  PGPPSKPQVTDVTKNSVTLSW-QPGTPGTLPASAYIIE--AFSQSVSNSWQTV-ANHVKT 593

Query: 994  EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
              Y +  L+ N +Y F V A+N  GL  PS +S+  + ++ +    G  H     E+  D
Sbjct: 594  TLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKEL-GD 652

Query: 1054 SLVLQWKPPVHSGRTP------------VTGYFVDLKEAKAKE--DQWRGLNEAAIKNVY 1099
             LV    P V +  T             + GY V  ++    +    W+ L+        
Sbjct: 653  VLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERS 712

Query: 1100 LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNV 1148
              +  LK+GV+Y  +VR       G  S+       E  P      V V
Sbjct: 713  AVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTV 761



 Score = 39.7 bits (91), Expect = 0.025
 Identities = 67/311 (21%), Positives = 120/311 (38%), Gaps = 34/311 (10%)

Query: 1347 FQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF 1406
            F+R  ++R+        ++  V  E  V  +C+V    + T + W KD+ ++    ++D 
Sbjct: 238  FERPTFLRRP-------INQVVLEEEAVEFRCQVQGDPQPT-VRWKKDDADLPRG-RYDI 288

Query: 1407 KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDL 1466
            KD   TL I +    D G Y  I ++  GK ++   L   A  + ++    +I      +
Sbjct: 289  KDDY-TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTV 347

Query: 1467 KIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDK 1526
                  +G    +   ++ ++   N        + + R     TG+   L I     +D 
Sbjct: 348  TFPCETKGNPQPA--VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGD---LTITNIQRSDA 402

Query: 1527 GKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQE 1586
            G Y+ +           + ++G    +A  E   +    + ++    +L G  +     +
Sbjct: 403  GYYICQ----------ALTVAGSILAKAQLEVTDV----LTDRPPPIILQGPANQTLAVD 448

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
            G AL L C   GDP P +SWLK        D      E G      I  +  +D+G Y  
Sbjct: 449  GTAL-LKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT---LQIKNLRISDTGTYTC 504

Query: 1647 VVKNKYGSETS 1657
            V  +  G ETS
Sbjct: 505  VATSSSG-ETS 514



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1584 IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
            + E +A+   C V GDP P V W K++  L        +++        I    + D G 
Sbjct: 252  VLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-----RYDIKDDYTLRIKKTMSTDEGT 306

Query: 1644 YGLVVKNKYGSETSDFTVSVFIPEE 1668
            Y  + +N+ G   +  T++V  P +
Sbjct: 307  YMCIAENRVGKMEASATLTVRAPPQ 331



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 30/104 (28%), Positives = 41/104 (39%), Gaps = 2/104 (1%)

Query: 628 TEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVN 687
           TEE PS    P   T L+V     + + +SW PP      GI+   +    G E    +N
Sbjct: 748 TEEAPSAP--PQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHIN 805

Query: 688 TELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTV 731
             +        +  L  G  Y   V  S SAGVG  SE   + +
Sbjct: 806 KTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIII 849



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 6/85 (7%)

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDD----HCNLKFEAGRTAYFTI- 1633
            P  V + +G+   L C   G P P + W K+ + + +D        +   +G   +  I 
Sbjct: 53   PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIV 112

Query: 1634 -NGVSTADSGKYGLVVKNKYGSETS 1657
                S  D G Y  V +N  G   S
Sbjct: 113  HGRRSKPDEGSYVCVARNYLGEAVS 137


>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
           ROBO2b [Homo sapiens]
          Length = 1378

 Score = 95.5 bits (236), Expect = 4e-19
 Identities = 118/502 (23%), Positives = 183/502 (36%), Gaps = 72/502 (14%)

Query: 277 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYK----NQVPINVHANPGKYIIESRY 332
           P+F+++PR   V +   V   C   G P+P V W K    N +  N    P      S  
Sbjct: 314 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 373

Query: 333 GMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSF 392
           G   L I      D   Y   A+ V G + A A + V     +        G +   L+ 
Sbjct: 374 G--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAV 431

Query: 393 GVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPL-- 450
             T                            L C+    P      P I W + G     
Sbjct: 432 DGTAL--------------------------LKCKATGDP-----LPVISWLKEGFTFPG 460

Query: 451 -SPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADA----- 504
             P   +Q     E+ TL   +L   D G YT           +SA + V ++ A     
Sbjct: 461 RDPRATIQ-----EQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKN 515

Query: 505 -EIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTP 563
            ++   P  P   +  +  K+ + +SW QP   G  P   Y I+       +  Q     
Sbjct: 516 YDLSDLPGPPSKPQVTDVTKNSVTLSW-QPGTPGTLPASAYIIEAFSQSVSNSWQTVANH 574

Query: 564 VKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKAR-LKSRPSAPWT 622
           VK   + V GL     Y+F VRA+N  G+  PS +S+PV   D +  A+ +  R      
Sbjct: 575 VKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKEL 634

Query: 623 GQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTEN 682
           G ++V    P    V   PT + VT        +  +P   +G+  +MY        T +
Sbjct: 635 GDVLVRLHNP----VVLTPTTVQVT------WTVDRQPQFIQGYR-VMYRQTSGLQATSS 683

Query: 683 WQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAP 742
           WQ ++ ++P +     L +L +G +Y  +VR   +   G  SE+  V       + P AP
Sbjct: 684 WQNLDAKVPTERSA-VLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTE---EAPSAP 739

Query: 743 GKIIP----SRNTDTSVVVSWE 760
            + +          TS+ VSW+
Sbjct: 740 PQSVTVLTVGSYNSTSISVSWD 761



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 1038 VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
            +PGPP   + ++V K+S+ L W+P    G  P + Y ++   +++  + W+ +    +K 
Sbjct: 521  LPGPPSKPQVTDVTKNSVTLSWQPGT-PGTLPASAYIIEAF-SQSVSNSWQTVANH-VKT 577

Query: 1098 VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPV 1133
                VRGL+    Y+F VRAIN  G+  PS ++ PV
Sbjct: 578  TLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPV 613



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 88/340 (25%), Positives = 133/340 (39%), Gaps = 35/340 (10%)

Query: 715  SNSAGVGEPSEATEVTVVG-------DKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAK- 766
            ++S+G    S   +VT  G       D  D+P  P K   +  T  SV +SW+       
Sbjct: 491  TSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTL 550

Query: 767  ELVGYYIEA-SVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQD 825
                Y IEA S + S  W+   N+ VK + +T  GL     Y+F VRA+N  GLS+ S  
Sbjct: 551  PASAYIIEAFSQSVSNSWQTVANH-VKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPM 609

Query: 826  SEAI---EVKAAIGGGVSPDVCPALSD------EPGGLTASRGRVH---EASPPTFQKDA 873
            S+ +   ++     G     V   L D       P  LT +  +V    +  P   Q   
Sbjct: 610  SDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYR 669

Query: 874  LLGSKPNKPSLPSSSQNLG---QTEVSKV----SETVQEELTPPPQKAAPQGKSKSDPLK 926
            ++  + +     SS QNL     TE S V     + V  E+   P     QG        
Sbjct: 670  VMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTV 729

Query: 927  KKTDRAPPSPPCDITCLE--SFRD-SMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKW 983
            + T+ AP +PP  +T L   S+   S+ + W  P         G    Y+    G   ++
Sbjct: 730  RTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPP---DHQNGIIQEYKIWCLGNETRF 786

Query: 984  REANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPS 1023
                    +  +  I  L   + Y+ +VAA   AG+G  S
Sbjct: 787  HINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS 826



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 62/275 (22%), Positives = 96/275 (34%), Gaps = 74/275 (26%)

Query: 233 EETSEKKSRKVVIREKAERLSLR----------------------KTLEETETYHAKLNE 270
           E T   K  KV I +K ER+S+R                        + E ++  A+L  
Sbjct: 162 EPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELT- 220

Query: 271 DHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIES 330
             +   P F+ +P +  V E+E V+  C + G P+P V W K+   +      G+Y I+ 
Sbjct: 221 --VFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADL----PRGRYDIKD 274

Query: 331 RYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPL 390
            Y   TL I      D   Y   A N  G++ A A++ V+                  P 
Sbjct: 275 DY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVR-----------------APP 314

Query: 391 SFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNG--- 447
            F V P                     +G T++  C     P     QP + W + G   
Sbjct: 315 QFVVRPRD---------------QIVAQGRTVTFPCETKGNP-----QPAVFWQKEGSQN 354

Query: 448 --VPLSPSKWVQTLWSGERATLTFSHLNKEDEGLY 480
              P  P +            LT +++ + D G Y
Sbjct: 355 LLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYY 389



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 53/229 (23%), Positives = 83/229 (36%), Gaps = 19/229 (8%)

Query: 934  PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
            P PP      +  ++S+ L W QP   G    + Y +        V   W+      V  
Sbjct: 522  PGPPSKPQVTDVTKNSVTLSW-QPGTPGTLPASAYIIE--AFSQSVSNSWQTV-ANHVKT 577

Query: 994  EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
              Y +  L+ N +Y F V A+N  GL  PS +S+  + ++ +    G  H     E+  D
Sbjct: 578  TLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKEL-GD 636

Query: 1054 SLVLQWKPPVHSGRTP------------VTGYFVDLKEAKAKE--DQWRGLNEAAIKNVY 1099
             LV    P V +  T             + GY V  ++    +    W+ L+        
Sbjct: 637  VLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERS 696

Query: 1100 LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNV 1148
              +  LK+GV+Y  +VR       G  S+       E  P      V V
Sbjct: 697  AVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTV 745



 Score = 39.7 bits (91), Expect = 0.025
 Identities = 67/311 (21%), Positives = 120/311 (38%), Gaps = 34/311 (10%)

Query: 1347 FQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF 1406
            F+R  ++R+        ++  V  E  V  +C+V    + T + W KD+ ++    ++D 
Sbjct: 222  FERPTFLRRP-------INQVVLEEEAVEFRCQVQGDPQPT-VRWKKDDADLPRG-RYDI 272

Query: 1407 KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDL 1466
            KD   TL I +    D G Y  I ++  GK ++   L   A  + ++    +I      +
Sbjct: 273  KDDY-TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTV 331

Query: 1467 KIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDK 1526
                  +G    +   ++ ++   N        + + R     TG+   L I     +D 
Sbjct: 332  TFPCETKGNPQPA--VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGD---LTITNIQRSDA 386

Query: 1527 GKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQE 1586
            G Y+ +           + ++G    +A  E   +    + ++    +L G  +     +
Sbjct: 387  GYYICQ----------ALTVAGSILAKAQLEVTDV----LTDRPPPIILQGPANQTLAVD 432

Query: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
            G AL L C   GDP P +SWLK        D      E G      I  +  +D+G Y  
Sbjct: 433  GTAL-LKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT---LQIKNLRISDTGTYTC 488

Query: 1647 VVKNKYGSETS 1657
            V  +  G ETS
Sbjct: 489  VATSSSG-ETS 498



 Score = 37.7 bits (86), Expect = 0.095
 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 1584 IQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGK 1643
            + E +A+   C V GDP P V W K++  L        +++        I    + D G 
Sbjct: 236  VLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-----RYDIKDDYTLRIKKTMSTDEGT 290

Query: 1644 YGLVVKNKYGSETSDFTVSVFIPEE 1668
            Y  + +N+ G   +  T++V  P +
Sbjct: 291  YMCIAENRVGKMEASATLTVRAPPQ 315



 Score = 37.0 bits (84), Expect = 0.16
 Identities = 30/104 (28%), Positives = 41/104 (39%), Gaps = 2/104 (1%)

Query: 628 TEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVN 687
           TEE PS    P   T L+V     + + +SW PP      GI+   +    G E    +N
Sbjct: 732 TEEAPSAP--PQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHIN 789

Query: 688 TELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTV 731
             +        +  L  G  Y   V  S SAGVG  SE   + +
Sbjct: 790 KTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIII 833



 Score = 32.0 bits (71), Expect = 5.2
 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 6/85 (7%)

Query: 1579 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDD----HCNLKFEAGRTAYFTI- 1633
            P  V + +G+   L C   G P P + W K+ + + +D        +   +G   +  I 
Sbjct: 37   PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIV 96

Query: 1634 -NGVSTADSGKYGLVVKNKYGSETS 1657
                S  D G Y  V +N  G   S
Sbjct: 97   HGRRSKPDEGSYVCVARNYLGEAVS 121


>gi|205360934 fibronectin type III domain containing 3B [Homo sapiens]
          Length = 1204

 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 156/665 (23%), Positives = 246/665 (36%), Gaps = 120/665 (18%)

Query: 509  APAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDS-WSQCNDTPVKFA 567
            AP  P   K    +K  + + WK P +D GS I  Y ++  E   +S + QC     K  
Sbjct: 378  APECPFPPKLAHRSKSSLTLQWKAP-IDNGSKITNYLLEWDEGKRNSGFRQCFFGSQKHC 436

Query: 568  RFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIV 627
            +  +T L     Y FR+ A N +G    S  S+ V                         
Sbjct: 437  K--LTKLCPAMGYTFRLAARNDIG---TSGYSQEVVCY---------------------- 469

Query: 628  TEEEPSEGIVPGPPTDLSVTEATRSYVVLSW-KPPGQRGHEGIMYFVEKCEAGTENWQRV 686
                 + G +P  P+   +  A  ++V L W KP G    E I Y +E  E   EN    
Sbjct: 470  -----TLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCSPEEVITYTLEIQE--DENDNLF 522

Query: 687  NTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKII 746
            + +   +     + +L     Y FR+  SN+ G   PSE    T   D+   P  P  ++
Sbjct: 523  HPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRP--LV 580

Query: 747  PSRNTDTSVVVSWEESKD--AKELVGYYIEASVAGS--GKWEPCNNNPVKGSRFTCHGLV 802
                T     V W+  KD    E++ Y +E +   S   +WE   +     + +T   L 
Sbjct: 581  KGPVTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEANQWEVAYSG--SATEYTFTHLK 638

Query: 803  TGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVC--PALSDEPG-------- 852
             G  Y  R   ++  G   +SQ SE++ V+      ++P  C  P +   P         
Sbjct: 639  PGTLYKLRACCISTGG---HSQCSESLPVRTL---SIAPGQCRPPRVLGRPKHKEVHLEW 692

Query: 853  --GLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPP 910
                + S   V E S    + + +     + P L  +  NL    V +       +    
Sbjct: 693  DVPASESGCEVSEYSVEMTEPEDVASEVYHGPELECTVGNLLPGTVYRFRVRALND---- 748

Query: 911  PQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVL-GWKQPDKIGGAEITGYY 969
                   G      + + T  A P   C   C+    D  VL GW+ PD   GA+I+ Y 
Sbjct: 749  ------GGYGPYSDVSEITTAAGPPGQCKAPCISCTPDGCVLVGWESPDS-SGADISEYR 801

Query: 970  VNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLG--------- 1020
            + + E  + +   +   + +      ++I +L     Y  ++ A N AG G         
Sbjct: 802  LEWGEDEESLELIYHGTDTR------FEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQ 855

Query: 1021 ----APSAVSE-CFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFV 1075
                AP  VS  C   EE   A P  P +          LVL W+ P ++G + +  Y +
Sbjct: 856  TPASAPDPVSTLCVLEEEPLDAYPDSPSA---------CLVLNWEEPCNNG-SEILAYTI 905

Query: 1076 DLKEAKAKEDQWRGLNEAAIKNVYLKV-RGLKEGVSYVFRVRAINQAGVGKPSDLAGPVV 1134
            DL           G     + N  + V + L    +Y  R++AIN+ G G  S     + 
Sbjct: 906  DL-----------GDTSITVGNTTMHVMKDLLPETTYRIRIQAINEIGAGPFSQF---IK 951

Query: 1135 AETRP 1139
            A+TRP
Sbjct: 952  AKTRP 956



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 141/649 (21%), Positives = 229/649 (35%), Gaps = 110/649 (16%)

Query: 510  PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
            P  P   + + A   ++ + W +P       ++ Y ++  E   D+      T       
Sbjct: 475  PQMPSAPRLVRAGITWVTLQWSKPEGCSPEEVITYTLEIQEDENDNLFHPKYTGEDLT-C 533

Query: 570  PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
             V  L     Y FR+ A N  G   PS                           +++V  
Sbjct: 534  TVKNLKRSTQYKFRLTASNTEGKSCPS---------------------------EVLVCT 566

Query: 630  EEPSEGIVPGPPTDLSVTEATRSY-VVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNT 688
              P     PGPPT   V     S+   + W PP   G   I+ ++ +   G     +   
Sbjct: 567  TSPDR---PGPPTRPLVKGPVTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEANQWEV 623

Query: 689  ELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIP- 747
                 +  +    L  G  Y  R  C ++ G  + SE+  V  +        APG+  P 
Sbjct: 624  AYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSI------APGQCRPP 677

Query: 748  ---SRNTDTSVVVSWE--ESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCH--G 800
                R     V + W+   S+   E+  Y +E +       E   +    G    C    
Sbjct: 678  RVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTEP-----EDVASEVYHGPELECTVGN 732

Query: 801  LVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGG------GVSPDVCPAL---SDEP 851
            L+ G  Y FRVRA+N  G   YS  SE        G         +PD C  +   S + 
Sbjct: 733  LLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISCTPDGCVLVGWESPDS 792

Query: 852  GGLTASRGRVHEASPPTFQKDALLGSKPN---KPSLPSSS-----QNLGQTEVSKVSETV 903
             G   S  R+         +    G+      +  LP++      Q   Q      SE V
Sbjct: 793  SGADISEYRLEWGEDEESLELIYHGTDTRFEIRDLLPAAQYCCRLQAFNQAGAGPYSELV 852

Query: 904  QEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGA 963
              + TP    +AP   S    L+++   A P  P    CL       VL W++P    G+
Sbjct: 853  LCQ-TPA---SAPDPVSTLCVLEEEPLDAYPDSPS--ACL-------VLNWEEPCN-NGS 898

Query: 964  EITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPS 1023
            EI  Y ++  +            ++   +   + + +L     Y+ ++ A+N  G G   
Sbjct: 899  EILAYTIDLGDT-----------SITVGNTTMHVMKDLLPETTYRIRIQAINEIGAGP-- 945

Query: 1024 AVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQW---KPPVHSGRTPVTGYFVDLKEA 1080
              S+  K +  T  +P  P  L+C+     SL L+W       H+    V  Y + L++ 
Sbjct: 946  -FSQFIKAK--TRPLPPLPPRLECAAAGPQSLKLKWGDSNSKTHAAEDIV--YTLQLEDR 1000

Query: 1081 KAKEDQ-WRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1128
              +    +RG +         KV+ L E   Y FR++A ++AG G  S+
Sbjct: 1001 NKRFISIYRGPSHT------YKVQRLTEFTCYSFRIQAASEAGEGPFSE 1043



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 138/582 (23%), Positives = 209/582 (35%), Gaps = 81/582 (13%)

Query: 654  VVLSWKPPGQRG---HEGIM----YFVEKCEAGTENWQRV---NTELPVKSPRFALFDLA 703
            VVLSW PP       H G+     Y V   + G +   ++     EL        L DL 
Sbjct: 292  VVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGRDGKYKIIYSGEELECN-----LKDLR 346

Query: 704  EGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESK 763
                Y  RV    ++  G  SE    T      + P  P     +  + +S+ + W+   
Sbjct: 347  PATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPPKL---AHRSKSSLTLQWKAPI 403

Query: 764  D-AKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCH--GLVTGQSYIFRVRAVNAAGLS 820
            D   ++  Y +E      GK          GS+  C    L     Y FR+ A N  G S
Sbjct: 404  DNGSKITNYLLEWD---EGKRNSGFRQCFFGSQKHCKLTKLCPAMGYTFRLAARNDIGTS 460

Query: 821  EYSQDSEAIEVKAAIGGGVSPDVCPALS-----------DEPGGLTASRGRVHEASPPTF 869
             YSQ+     V   +G        P L             +P G +      +       
Sbjct: 461  GYSQEV----VCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCSPEEVITYTLEIQED 516

Query: 870  QKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKS-KSDPLKKK 928
            + D L   K     L  + +NL ++   K   T              +GKS  S+ L   
Sbjct: 517  ENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNT----------EGKSCPSEVLVCT 566

Query: 929  TDRAPPSPPC-DITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDG--VPGKWRE 985
            T    P PP   +           + W  P   GG+EI  Y +   E+ DG     +W  
Sbjct: 567  TSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKDNGGSEILKYLL---EITDGNSEANQWEV 623

Query: 986  ANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPG---PP 1042
            A   + +E  Y  ++LK   +Y+ +   ++  G    S  SE       +IA PG   PP
Sbjct: 624  AYSGSATE--YTFTHLKPGTLYKLRACCISTGG---HSQCSESLPVRTLSIA-PGQCRPP 677

Query: 1043 HSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAK-AKEDQWRGLNEAAIKNVYLK 1101
              L     +   + L+W  P       V+ Y V++ E +    + + G        +   
Sbjct: 678  RVL--GRPKHKEVHLEWDVPASESGCEVSEYSVEMTEPEDVASEVYHG------PELECT 729

Query: 1102 VRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPG-TKEVVVNVDDDGVISLNFEC 1160
            V  L  G  Y FRVRA+N  G G  SD++    A   PG  K   ++   DG + + +E 
Sbjct: 730  VGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISCTPDGCVLVGWE- 788

Query: 1161 DKMTPKSEFSWSKDYVST--EDSPRLEVESKGNKTKMTFKDL 1200
               +P S  +   +Y     ED   LE+   G  T+   +DL
Sbjct: 789  ---SPDSSGADISEYRLEWGEDEESLELIYHGTDTRFEIRDL 827



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 89/386 (23%), Positives = 141/386 (36%), Gaps = 70/386 (18%)

Query: 453 SKWVQTLWSGERATLTFSHLNKEDEGLYTIR---VRMGEYYEQYSAYVFVRDADAEIEGA 509
           ++W +  +SG     TF+HL      LY +R   +  G +  Q S  + VR     I   
Sbjct: 619 NQW-EVAYSGSATEYTFTHLKPGT--LYKLRACCISTGGH-SQCSESLPVRTLS--IAPG 672

Query: 510 PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARF 569
              P  V     +K+ + + W  PA + G  +  Y ++  E   D  S+    P      
Sbjct: 673 QCRPPRVLGRPKHKE-VHLEWDVPASESGCEVSEYSVEMTEP-EDVASEVYHGPE--LEC 728

Query: 570 PVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTE 629
            V  L+ G  Y FRVRA+N  G G  S VSE   A  P                      
Sbjct: 729 TVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGP---------------------- 766

Query: 630 EEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTE 689
                   PG      ++      V++ W+ P   G +   Y +E      E+ + +   
Sbjct: 767 --------PGQCKAPCISCTPDGCVLVGWESPDSSGADISEYRLE----WGEDEESLELI 814

Query: 690 LPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSE-------ATEVTVVGDKLDIPKAP 742
                 RF + DL     YC R++  N AG G  SE       A+    V     + + P
Sbjct: 815 YHGTDTRFEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEP 874

Query: 743 GKIIPSRNTDTSVVVSWEE-SKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCH-- 799
               P  +    +V++WEE   +  E++ Y I+             +  +     T H  
Sbjct: 875 LDAYPD-SPSACLVLNWEEPCNNGSEILAYTID-----------LGDTSITVGNTTMHVM 922

Query: 800 -GLVTGQSYIFRVRAVNAAGLSEYSQ 824
             L+   +Y  R++A+N  G   +SQ
Sbjct: 923 KDLLPETTYRIRIQAINEIGAGPFSQ 948



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 72/341 (21%), Positives = 124/341 (36%), Gaps = 63/341 (18%)

Query: 526  IIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVR 585
            ++++W++P  + GS IL Y ID   +G  S +  N T        +  L+   +Y  R++
Sbjct: 886  LVLNWEEPC-NNGSEILAYTID---LGDTSITVGNTT-----MHVMKDLLPETTYRIRIQ 936

Query: 586  AVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLS 645
            A+N++G G  S+              + K+RP                   +P  P  L 
Sbjct: 937  AINEIGAGPFSQF------------IKAKTRP-------------------LPPLPPRLE 965

Query: 646  VTEATRSYVVLSWKPPGQRGH--EGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLA 703
               A    + L W     + H  E I+Y ++  +      +R  +     S  + +  L 
Sbjct: 966  CAAAGPQSLKLKWGDSNSKTHAAEDIVYTLQLEDRN----KRFISIYRGPSHTYKVQRLT 1021

Query: 704  EGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESK 763
            E   Y FR++ ++ AG G  SE    +         KAP     ++    S  + WE   
Sbjct: 1022 EFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPR---VTQLEGNSCEILWETVP 1078

Query: 764  DAK-ELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEY 822
              K + V Y ++  V    +++       + + F   GL T   Y FRV A         
Sbjct: 1079 SMKGDPVNYILQVLVGRESEYKQVYKG--EEATFQISGLQTNTDYRFRVCACR------- 1129

Query: 823  SQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHE 863
                  ++    + G  SP     L      LT   G + +
Sbjct: 1130 ----RCLDTSQELSGAFSPSAAFVLQRSEVMLTGDMGSLDD 1166


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,096,384
Number of Sequences: 37866
Number of extensions: 3240114
Number of successful extensions: 21967
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 208
Number of HSP's successfully gapped in prelim test: 398
Number of HSP's that attempted gapping in prelim test: 9535
Number of HSP's gapped (non-prelim): 7107
length of query: 1685
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1569
effective length of database: 13,855,062
effective search space: 21738592278
effective search space used: 21738592278
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.