BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7662236 TSC22 domain family, member 2 [Homo sapiens] (780 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 1548 0.0 gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 252 8e-67 gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens] 120 4e-27 gi|13569901 TSC22 domain family, member 4 [Homo sapiens] 117 5e-26 gi|37622901 TSC22 domain family, member 3 isoform 2 [Homo sapiens] 108 1e-23 gi|37622903 TSC22 domain family, member 3 isoform 1 [Homo sapiens] 107 3e-23 gi|163965366 nascent polypeptide-associated complex alpha subuni... 101 3e-21 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 94 6e-19 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 91 4e-18 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 88 3e-17 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 87 6e-17 gi|110832843 TBP-associated factor 4 [Homo sapiens] 86 1e-16 gi|160707881 formin 2 [Homo sapiens] 83 9e-16 gi|62865625 TSC22 domain family, member 3 isoform 3 [Homo sapiens] 81 3e-15 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 79 2e-14 gi|116284392 mucin 2 precursor [Homo sapiens] 79 2e-14 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 79 2e-14 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 78 3e-14 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 77 6e-14 gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 77 8e-14 gi|55750053 atrophin-1 [Homo sapiens] 76 1e-13 gi|55750041 atrophin-1 [Homo sapiens] 76 1e-13 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 75 2e-13 gi|150170670 piccolo isoform 2 [Homo sapiens] 75 2e-13 gi|150378539 piccolo isoform 1 [Homo sapiens] 75 2e-13 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 73 1e-12 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 73 1e-12 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 73 1e-12 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 72 2e-12 gi|112421108 capicua homolog [Homo sapiens] 72 2e-12 >gi|7662236 TSC22 domain family, member 2 [Homo sapiens] Length = 780 Score = 1548 bits (4009), Expect = 0.0 Identities = 780/780 (100%), Positives = 780/780 (100%) Query: 1 MSKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATDYGPE 60 MSKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATDYGPE Sbjct: 1 MSKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATDYGPE 60 Query: 61 EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST 120 EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST Sbjct: 61 EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST 120 Query: 121 LAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRW 180 LAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRW Sbjct: 121 LAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRW 180 Query: 181 TCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPES 240 TCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPES Sbjct: 181 TCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPES 240 Query: 241 GTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAAT 300 GTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAAT Sbjct: 241 GTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAAT 300 Query: 301 GPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYP 360 GPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYP Sbjct: 301 GPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYP 360 Query: 361 QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNAS 420 QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNAS Sbjct: 361 QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNAS 420 Query: 421 SVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQS 480 SVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQS Sbjct: 421 SVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQS 480 Query: 481 VPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQ 540 VPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQ Sbjct: 481 VPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQ 540 Query: 541 LSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEP 600 LSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEP Sbjct: 541 LSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEP 600 Query: 601 LPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTAFY 660 LPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTAFY Sbjct: 601 LPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTAFY 660 Query: 661 QAFHLNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELV 720 QAFHLNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELV Sbjct: 661 QAFHLNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELV 720 Query: 721 ERNSLLERENALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQPPQQPNVSSA 780 ERNSLLERENALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQPPQQPNVSSA Sbjct: 721 ERNSLLERENALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQPPQQPNVSSA 780 >gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] Length = 1073 Score = 252 bits (644), Expect = 8e-67 Identities = 256/808 (31%), Positives = 357/808 (44%), Gaps = 158/808 (19%) Query: 71 TLNNVGDAETPGTVSPNLL--------LDGQLAAAAAAPANGGGVVSARSV---SGALAS 119 T+NNV + G+ +PN+ + +AA + G GV S +V SG Sbjct: 312 TVNNV-NITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNG 370 Query: 120 TLAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGR 179 T++++A + P A AG + G V++ QP T +SRFRV+KLD S EP+++GR Sbjct: 371 TISSSAAVSSVPNAA-----AGMTGGSVSSQQQQP-TVNTSRFRVVKLD-SSSEPFKKGR 423 Query: 180 WTCMEYYERDS-----DSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQG 234 WTC E+YE+++ + ++ + + ++ + + T+ER+S G++ S V ++ Sbjct: 424 WTCTEFYEKENAVPATEGVLINKVVETVKQNP-IEVTSERESTSGSSVSSSVSTLSHYTE 482 Query: 235 AHGP-ESGTDSSLTAVSQLPPSEKMSQP-----TPAQPQSFSVGQPQPPPPPVGGAVAQS 288 + G E G + + Q ++ QP T Q S G P + +++QS Sbjct: 483 SVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQS 542 Query: 289 SAP----------------LPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLP----PTN 328 L P P AT M+AA QP G T P+ Sbjct: 543 QISQVQLQSQELSYQQKQGLQPVPLQAT-----MSAATGIQPSPVNVVGVTSALGQQPSI 597 Query: 329 VTLAQPAM----SLPPQPGPAVGAPAAQQPQQFAYPQP----QIPPGHLLPVQPSGQSEY 380 +LAQP + + PP P GAP QQ Q+ QP Q+ PGH+ V + SEY Sbjct: 598 SSLAQPQLPYSQAAPPVQTPLPGAPPPQQ-LQYGQQQPMVSTQMAPGHVKSVTQNPASEY 656 Query: 381 LQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNA------SSVGAQLMGASSQP- 433 +QQ S QPSS G A +PV Q ++V AQ GAS QP Sbjct: 657 VQQQPILQTAMSSGQPSSAGVGAG---TTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPV 713 Query: 434 SEAMAPRTGPAQGGQVAPC-QPTGVPPATVGGVVQPCLGPAGAGQPQS---VPPPQMG-- 487 +A A + G Q+A Q +P A Q G P S VPP Q G Sbjct: 714 GQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGII 773 Query: 488 ------------------GSGPLSAVPGGPHAVVPGVPNV-----PAAVPAPSVPSVSTT 524 L VP P V P + PA PS S+S T Sbjct: 774 HQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVT 833 Query: 525 SVT-------MPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDL 577 S MP+ P L Q ++ TP +++ +++Q V P T++ Q L Sbjct: 834 SQVSSTGPSGMPSAPTNLVPPQNIAQ-TPATQNGNLVQSVSQPPLIATNTNLPLAQQIPL 892 Query: 578 SQFQTQTQPLV----GQVDDTRRKSEP----LPQPPLSLIAENKPVVKPPVADSLANPLQ 629 S Q Q L Q++D RR +EP LPQ +S + V + SLA Sbjct: 893 SSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQT-ISGDSGGMSAVSDGSSSSLAASAS 951 Query: 630 LTPMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDNK 689 L P+ V + P+ ED +S+SG VVAIDNK Sbjct: 952 LFPLK-----VLPLTTPLVDGED-----------------------ESSSGASVVAIDNK 983 Query: 690 IEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPT-- 747 IEQAMDLVKSHLMYAVREEVEVLKEQIKEL+E+NS LE+EN LLK+L+S +QL+Q Sbjct: 984 IEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQL 1043 Query: 748 QQANPGSTSQQQAVIAQPPQPTQPPQQP 775 Q +P +T+Q Q TQPP QP Sbjct: 1044 QTGSPPATTQPQGT-------TQPPAQP 1064 Score = 36.6 bits (83), Expect = 0.092 Identities = 95/470 (20%), Positives = 145/470 (30%), Gaps = 131/470 (27%) Query: 240 SGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPF-PGA 298 +G S+ T+ PP + P PA + S PQPPPP ++Q+ P PG Sbjct: 46 TGVGSNATSSEDFPPPSLLQPPPPA---ASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGG 102 Query: 299 A----------TGPQPMMAAAQPSQPQGAGPGGQTLPP--------------TNVTLAQP 334 T P +A S ++ +V+L++ Sbjct: 103 TQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRA 162 Query: 335 AMSLPPQPGPA---------VGAPAAQQPQQFAYPQPQIP--PGHLLPVQPSGQSEYLQQ 383 P+ + P A P Q PQP +P P + + + +L Sbjct: 163 TDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHH 222 Query: 384 H---------VAGLQPPSPAQPSST----GAAASPATAATLPVGTGQNASSVG-AQLMGA 429 H G PS +S G +SP + G+ + + V + + Sbjct: 223 HHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSS 282 Query: 430 SSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLG------------------ 471 S P+ M P+ G + TG +TV V +G Sbjct: 283 SGSPASVMTNMRAPSTTGGIGINSVTGT--STVNNVNITAVGSFNPNVTSSMLGNVNIST 340 Query: 472 ---PAGAGQPQSVPPPQMGGSGP--LSAVPGG---PHAVVPGVPNVPAAVPAPSV----- 518 P+ AG SV P G LS + G A V VPN A + SV Sbjct: 341 SNIPSAAG--VSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQ 398 Query: 519 -PSVSTTSV------------------------------------------TMPNVPAPL 535 P+V+T+ T+ P + Sbjct: 399 QPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEV 458 Query: 536 AQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQ 585 ++ +S + VS S S + H + G APT + Q Q Q Q Q Sbjct: 459 TSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQ 508 Score = 30.0 bits (66), Expect = 8.6 Identities = 31/103 (30%), Positives = 41/103 (39%), Gaps = 10/103 (9%) Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFP 296 G SG+ S+L A S S P QPPPP A + +S P PP P Sbjct: 32 GSGSGSASALNAAGTGVGSNATSSEDFPPPSLL-----QPPPP----AASSTSGPQPPPP 82 Query: 297 GAATGPQPMMAAAQPSQPQGAGPGGQT-LPPTNVTLAQPAMSL 338 + AQP P G ++ T+VT AQ + S+ Sbjct: 83 QSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISASI 125 >gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens] Length = 144 Score = 120 bits (302), Expect = 4e-27 Identities = 70/113 (61%), Positives = 82/113 (72%), Gaps = 9/113 (7%) Query: 665 LNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNS 724 L T S L +S+SG VVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKEL+E+NS Sbjct: 30 LGTENASVRLDNSSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNS 89 Query: 725 LLERENALLKSLSSNDQLSQLPT--QQANPGSTSQQQAVIAQPPQPTQPPQQP 775 LE+EN LLK+L+S +QL+Q Q +P +T+Q Q TQPP QP Sbjct: 90 QLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGT-------TQPPAQP 135 >gi|13569901 TSC22 domain family, member 4 [Homo sapiens] Length = 395 Score = 117 bits (292), Expect = 5e-26 Identities = 109/362 (30%), Positives = 154/362 (42%), Gaps = 64/362 (17%) Query: 443 PAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAV--PGG-- 498 P P PTG PP G +P P G G P++ PP S V P G Sbjct: 25 PGASDPPTPQPPTGPPPRLPNG--EPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLG 82 Query: 499 -------------------PHA---VVPGVPNVPAAVPAPSVPS---VSTTSVTMPNVPA 533 PH+ ++ G+ S+ S +++ + P P+ Sbjct: 83 EPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPS 142 Query: 534 PLAQSQ----QLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVG 589 L+Q + +P ++ S +G + P A P S S Q +P G Sbjct: 143 GLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKP-PLSASSPQQRPPEPETG 201 Query: 590 QVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDG 649 + T R + PLP + A PP++ A ++L M A P+D Sbjct: 202 ESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLR-MELGAPEEMGQVPPLDS 260 Query: 650 DEDRNPSTAFYQAFHLNTLKESKSLW------------------------DSASGGGVVA 685 R S A Y + + +S + D + G +V Sbjct: 261 ---RPSSPALYFTHDASLVHKSPDPFGAVAAQKFSLAHSMLAISGHLDSDDDSGSGSLVG 317 Query: 686 IDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQL 745 IDNKIEQAMDLVKSHLM+AVREEVEVLKEQI+EL ERN+ LE+EN LL++L+S +QL+QL Sbjct: 318 IDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRELAERNAALEQENGLLRALASPEQLAQL 377 Query: 746 PT 747 P+ Sbjct: 378 PS 379 Score = 83.6 bits (205), Expect = 7e-16 Identities = 94/327 (28%), Positives = 130/327 (39%), Gaps = 41/327 (12%) Query: 125 ATSAPAPGAPGGP--QLAGSSAGPVTAAP------SQPPTTCSSRFRVIKLDHGSGEPYR 176 A+ P P P GP +L P S PP SSRFRV+KL HG GEPYR Sbjct: 27 ASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPYR 86 Query: 177 RGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASM-QGA 235 RGRWTC++ YERD + + IR +S G G + +AS+ GA Sbjct: 87 RGRWTCVDVYERDLEPHSFGGLLEGIRGAS---------GGAGGRSLDSRLELASLGLGA 137 Query: 236 HGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPF 295 P SG T+ + PP + P P Q +SF+ G +G V S A Sbjct: 138 PTPPSGLSQGPTSWLRPPP----TSPGP-QARSFTGG--------LGQLVVPSKAKAEKP 184 Query: 296 PGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQ 355 P +A+ PQ + + G LP V P A + Sbjct: 185 PLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRM 244 Query: 356 QFAYPQP--QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPV 413 + P+ Q+PP L +PS + Y H A L SP P AA + A ++ Sbjct: 245 ELGAPEEMGQVPP---LDSRPSSPALYF-THDASLVHKSP-DPFGAVAAQKFSLAHSMLA 299 Query: 414 GTG---QNASSVGAQLMGASSQPSEAM 437 +G + S L+G ++ +AM Sbjct: 300 ISGHLDSDDDSGSGSLVGIDNKIEQAM 326 >gi|37622901 TSC22 domain family, member 3 isoform 2 [Homo sapiens] Length = 134 Score = 108 bits (271), Expect = 1e-23 Identities = 63/111 (56%), Positives = 76/111 (68%), Gaps = 14/111 (12%) Query: 671 SKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLEREN 730 S L +SASG VVAIDNKIEQAMDLVK+HLMYAVREEVE+LKEQI+ELVE+NS LEREN Sbjct: 35 SVKLDNSASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLEREN 94 Query: 731 ALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQP--PQQPNVSS 779 LLK+L+S +QL + Q + + P P P P+ P S+ Sbjct: 95 TLLKTLASPEQLEKF------------QSCLSPEEPAPESPQVPEAPGGSA 133 >gi|37622903 TSC22 domain family, member 3 isoform 1 [Homo sapiens] Length = 200 Score = 107 bits (268), Expect = 3e-23 Identities = 61/105 (58%), Positives = 73/105 (69%), Gaps = 14/105 (13%) Query: 677 SASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSL 736 SASG VVAIDNKIEQAMDLVK+HLMYAVREEVE+LKEQI+ELVE+NS LEREN LLK+L Sbjct: 107 SASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTL 166 Query: 737 SSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQP--PQQPNVSS 779 +S +QL + Q + + P P P P+ P S+ Sbjct: 167 ASPEQLEKF------------QSCLSPEEPAPESPQVPEAPGGSA 199 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 101 bits (251), Expect = 3e-21 Identities = 120/411 (29%), Positives = 146/411 (35%), Gaps = 48/411 (11%) Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQ---PQSFSV-GQPQPP---PPPVGGAVAQSS 289 GP + A+S S K ++ TPA P S S G P PP PP G A S Sbjct: 899 GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS 958 Query: 290 APLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAP 349 P P AAT P P A PS P T P A P+ P P PAV P Sbjct: 959 PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP-PAVTPP 1017 Query: 350 AAQ-QPQQFAYPQPQIPPGHLLPVQPSGQSEYL-------QQHVAGLQPP--SPAQPSST 399 + + P +P+ P P P G A L P PA PS Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK 1077 Query: 400 GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPP 459 GA PA P G S GA + A++ PS T P +G AP P PP Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG---APTTPAATPP 1134 Query: 460 ATVGGVVQPCLGPAGA-GQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSV 518 + GG+ P P GA P + PP GG L+ P G P PAA P Sbjct: 1135 SPKGGLATP--PPKGAPTTPAATPPSPKGG---LATPP------PKGAPTTPAATPPSPK 1183 Query: 519 PSVSTTSVT-MPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDL 577 ++T S P PA S + TP + AP T +A P+ L Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKG-----------APTTPAATPPSPKGGL 1232 Query: 578 SQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPP-VADSLANP 627 + + P K P PP A P PP + LA P Sbjct: 1233 ATPSPKGAPTTPAATPPSPKGGPATPPPKG--APTPPAATPPSLKGGLATP 1281 Score = 96.7 bits (239), Expect = 7e-20 Identities = 116/417 (27%), Positives = 149/417 (35%), Gaps = 67/417 (16%) Query: 231 SMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSA 290 S++GA P + T PPS K TP+ P+ + PP P GG Sbjct: 1075 SLKGAPTPPAAT----------PPSPKGGPATPS-PKGAPMPPAATPPSPKGGLAT---- 1119 Query: 291 PLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPA 350 PP GA T P AA P P+G G PP PA + PP P + P Sbjct: 1120 --PPHKGAPTTP-----AATPPSPKG----GLATPPPKGAPTTPAAT-PPSPKGGLATPP 1167 Query: 351 AQQPQQFAYPQPQIPPGHLLPVQPSGQ----SEYLQQHVAGLQPPSPAQPSSTGAAASPA 406 + P P G L P G + GL PSP GA +PA Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-----KGAPTTPA 1222 Query: 407 TAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVV 466 P G S GA A++ PS P T P +G AP P PP+ GG+ Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG---APTPPAATPPSLKGGLA 1279 Query: 467 QPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGG---PHAVVP----GVPNVPAAVPAPSVP 519 P GA P V PP G GP ++ P G P A P G P P AP+ P Sbjct: 1280 TP--PHKGAPNPAVVTPPSPKG-GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336 Query: 520 SVSTTSVT-MPNVPAPLAQSQQLSSHTPVSRS-----SSIIQHVG-----------LPLA 562 +V+ S P +PA S+ TP S+ ++ H G P Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKG-GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI 1395 Query: 563 PGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPP 619 P PTS LS + P+ + T K + P + + P P Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP 1452 Score = 71.2 bits (173), Expect = 3e-12 Identities = 164/673 (24%), Positives = 232/673 (34%), Gaps = 118/673 (17%) Query: 78 AETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAP------ 131 A TP +P L G LA A VV+ S G A++ A + PA Sbjct: 1263 APTPPAATPPSLKGG-LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK 1321 Query: 132 GAPGGPQLAGSSAGPVTAAPSQ------PPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEY 185 G+PG P G+ P PS P TT SS+ G P + T Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK-------GGPTTPSSKEGPTPPAA 1374 Query: 186 YERDSDSSVLT----RSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESG 241 +T + G I S D T+ L V + +GA P G Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAI-PSPKGDPTSPAVIPLSPKKAPATPV--TREGAATPSKG 1431 Query: 242 --TDSSLTAVS-QLPPSEKMSQPTPAQPQSF------SVGQPQPPPPPVGGAVAQSSAPL 292 T ++T VS + P+ + PA P S +V P P PP VA SS+P Sbjct: 1432 DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491 Query: 293 PPFPGAATGPQPMMAAAQPSQPQ--GAGPGGQTLP--PTNVTLAQ--------------P 334 A P + A PS P+ A P + P PT L++ P Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551 Query: 335 AMSLP-PQPGPAV----GAPAAQQPQQFAYPQPQIPPGH---------LLPVQPSGQSEY 380 AM++P P+ PA+ APA ++ + P P + L+P + S Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611 Query: 381 LQQHVAGLQPPS----PAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEA 436 + PPS PA P+ G SP + + + +SV ++ Q S+ Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671 Query: 437 MAPRTGPAQGGQ--VAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPP--QMGGSGPL 492 + + GP + VAP P P T P + A P P P + G GPL Sbjct: 1672 LPAKKGPTALKEVLVAPA-PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPL 1730 Query: 493 SAVPGGPHAVV-------------PGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQ 539 S V P V P P A P + T + +P P + S Sbjct: 1731 STVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASV 1790 Query: 540 QLSSHTPVSRSSSIIQHVGLPLAPGTHSAPT------SLPQSDLSQFQTQTQPLVGQVDD 593 + PVS LPLAP PT LP S ++ ++PL +D Sbjct: 1791 SAAPSPPVS----------LPLAPS--PVPTLPPKQQFLPSSPGLVLESPSKPLAPADED 1838 Query: 594 TRRKSEPLPQP-----PLSLIAENKPVVK----PPVADSLANPLQLTPMNSLATSVFSIA 644 P P+P P + N P K P S P+ S S + Sbjct: 1839 ELLPLIP-PEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDES 1897 Query: 645 IPVDGDEDRNPST 657 +P ++D +T Sbjct: 1898 VPELEEQDSTQAT 1910 Score = 61.6 bits (148), Expect = 3e-09 Identities = 87/359 (24%), Positives = 124/359 (34%), Gaps = 31/359 (8%) Query: 254 PSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQ 313 PS K + PA S G P P + AV S P P A T P P A P Sbjct: 1574 PSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP-- 1631 Query: 314 PQGAGPGGQTLPPTNVTLAQPAMSLPPQ---------PGPAVGAPAAQQP----QQFAYP 360 A G T PP + + + + P P + G PA + P + P Sbjct: 1632 ---APKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688 Query: 361 QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNAS 420 P+ P P + Q++ + P A+ S G ++ A A LPV Q S Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPV---QKDS 1745 Query: 421 SVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVP---PATVGGVVQPCLGPAGAGQ 477 S A+ AS P +AP A A +P A+V P + A Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805 Query: 478 PQSVPPPQM----GGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPA 533 P PP+ G + P P A +P P P V SV + N+P Sbjct: 1806 PVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSV-LVNMPT 1864 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVD 592 P +S + TP ++ + G + + L + D +Q TQ L + Sbjct: 1865 P--KSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAE 1921 Score = 47.4 bits (111), Expect = 5e-05 Identities = 100/485 (20%), Positives = 158/485 (32%), Gaps = 79/485 (16%) Query: 249 VSQLPPSEKMSQP---------TPAQPQSFSVGQPQPPPP---PVGGAVAQSSAPLPPFP 296 V+Q+P S + P A +F V PP P+ S A L P Sbjct: 428 VAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAP 487 Query: 297 GAATGPQPMMAAAQ--PSQPQGAGPGGQTLPPTNVTLAQPAMS-LPPQPGPAVGAPAAQQ 353 A P +A P P P P++V + P L P GAP + Sbjct: 488 VAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFS-- 545 Query: 354 PQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAAS--------- 404 P Q + P +LP+ + P P P +T A S Sbjct: 546 PAQAGLTTKKDPT--VLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGK 603 Query: 405 PATAATLPVGTGQNASSVGAQLMGA--SSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATV 462 PA++ T P+G +AS + S+ P + T + P GV P T Sbjct: 604 PASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTA 663 Query: 463 GGV----------------VQPCLGPAGAGQPQSVP-PPQMGGSGPLSAVPGG---PHAV 502 G + P P G ++P P + P++ P P A Sbjct: 664 KGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLAT 723 Query: 503 VPGVPNVPAAVPAPSVP------------SVSTTSVTMPNVPAPLAQSQQLSSHTPVSRS 550 + P +P +VP+PS+P +S TS P +P + S + + S Sbjct: 724 LVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS 783 Query: 551 SSIIQH-------VGLPLAPGTHSAPTSL----PQSDLSQFQTQTQPLVGQ-VDDTRRKS 598 + + +G+ ++P T PT P + + + P+ + + Sbjct: 784 KGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF 843 Query: 599 EPLPQPPLSLIAENKPVVKPPVADSLANPLQ-----LTPMNSLATSVFSIAIPVDGDEDR 653 + P + + P K S PL L P + SV ++ P +G Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903 Query: 654 NPSTA 658 P A Sbjct: 904 APKQA 908 Score = 43.5 bits (101), Expect = 8e-04 Identities = 93/424 (21%), Positives = 147/424 (34%), Gaps = 85/424 (20%) Query: 265 QPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTL 324 QPQ+ + P V A+ Q LPP A P+ AA Q S Sbjct: 18 QPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASP----------- 66 Query: 325 PPTNVTLAQPAMSLP-PQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQ 383 P+ T+A + +P PQ P P+ + I P P+ P+ Sbjct: 67 FPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGP----PISPAA------- 115 Query: 384 HVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGP 443 +A P T ++++P L + Q +S+ L+ +S PS A+A Sbjct: 116 -LALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLL--TSPPSVAVAESGSV 172 Query: 444 -AQGGQVAPCQP-----------------TGVPPATVGGVVQPCLGPAG------AGQPQ 479 +AP +P T PP V V C+ P A PQ Sbjct: 173 ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQ 232 Query: 480 SVPPPQMGGSGP------LSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPA 533 + P + + P +S+V P PG ++ V P+ S+ST S +P Sbjct: 233 TTPTTTLAIASPQVKDTTISSVLISPQN--PGSLSLKGPVSPPAALSLSTQS-----LPV 285 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDD 593 + + +TP P++ G+H AP L QS Q Q + D Sbjct: 286 VTSSQKTAGPNTPPD----------FPISLGSHLAP--LHQSSFGSVQLLGQTGPSALSD 333 Query: 594 TRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDR 653 K+ + ++ V PP L + ++ P A V + ++ D+ Sbjct: 334 PTVKTISVDHSSTGASYPSQRSVIPP----LPSRNEVVPATVAAFPVVAPSV------DK 383 Query: 654 NPST 657 PST Sbjct: 384 GPST 387 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 93.6 bits (231), Expect = 6e-19 Identities = 125/501 (24%), Positives = 166/501 (33%), Gaps = 47/501 (9%) Query: 107 VVSARSVSGALASTLAAAA---TSAPAPGAPGGP-----QLAGSSAGPVTAAPS---QPP 155 V ++ S L+A A TS P PG P + AG+ G APS +PP Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201 Query: 156 TTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERD 215 T + +H + EP R R S L R SS ++ Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAAR-------RRPSAGGGLQRPASRSLSSSATPLSSPAR 254 Query: 216 SGLGATGGSVVVVVASMQGAHG-----PESGTDSSLTAVSQLPP--SEKMSQPTPAQPQS 268 SG A G S G P T A L P S ++ P+P+ Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ 314 Query: 269 FSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQ-----PMMAAAQPSQPQGAGPGGQT 323 P P Q + PLP P + + P P A PSQ G T Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT-TSLGSPT 373 Query: 324 LPPTNVTLAQPAMSL----PPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSE 379 L T+ L P +S PPQ PA+ P Q P P P P P+ + Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433 Query: 380 YLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAP 439 +L Q P P Q + A+ P + + P + + + S S M+P Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493 Query: 440 RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGP 499 P P PP +Q P A + PP Q S P S P Sbjct: 494 SATP----------PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543 Query: 500 HAVVPGVPNVPAAVPAPSVPSVSTTSVTM--PNVPAPLAQSQQLSSHTPVSRSSSIIQHV 557 + +P P A P P P V + P+ PA TP +S + Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603 Query: 558 GLPLAPGTHSAPTSLPQSDLS 578 L LAPG P+ P S LS Sbjct: 604 TLALAPGPPPPPSRSPSSTLS 624 Score = 85.1 bits (209), Expect = 2e-16 Identities = 146/568 (25%), Positives = 193/568 (33%), Gaps = 83/568 (14%) Query: 96 AAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPG----GPQLAGSSAGPVTAAP 151 A A G + + +G S ++ A P A G P +S GPV++ Sbjct: 59 AERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118 Query: 152 SQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQT 211 TT L + E RG+ T E +R S Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKAT--EAPKR-----------------SALSAG 159 Query: 212 AERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSV 271 A RD+ G T G+ +A A G E G + PP+E + + + S Sbjct: 160 ARRDTS-GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG-PRKSVSSASEHST 217 Query: 272 GQPQPPP---PPVGGAVAQ------SSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGG- 321 +P P P GG + + SS+ P A +GP P+ P P G Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277 Query: 322 QTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYL 381 Q L P VT P P GP +P A P A Q Q PP LP P S Sbjct: 278 QALRPPQVT--PPRKDAAPALGPLSSSPLAT-PSPSAALQSQAPP--TLPATPHSSSLTC 332 Query: 382 QQHVA-GLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQ--PSEAMA 438 Q L PPSP+ P S SP AT P Q +S+G+ + A+ PS ++ Sbjct: 333 QLATPLPLAPPSPSAPPSLQTLPSPP--ATPP---SQATTSLGSPTLQATHSFLPSPPLS 387 Query: 439 P-RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSV-------------PPP 484 P T P Q P PP+ P L P PQ+ PPP Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPAS---PPLSPLATPSPQAPNALAVHLLQAPFSPPP 444 Query: 485 QMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544 P S P P V + PS S + + P+P A S Sbjct: 445 SPPVQAPFSP---------PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 495 Query: 545 TPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQP 604 TP ++ + L LA AP +L L + GQ + S LP Sbjct: 496 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--PSASLPMS 553 Query: 605 PLSLIAENKPVVKPPVADSLANPLQLTP 632 PL+ P PPV LA PL P Sbjct: 554 PLA----TPPPQAPPV---LAAPLLQVP 574 Score = 69.7 bits (169), Expect = 1e-11 Identities = 109/438 (24%), Positives = 159/438 (36%), Gaps = 65/438 (14%) Query: 248 AVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMA 307 A ++ P + TP P G P+PPPP A+ A A G +P+ Sbjct: 12 AAARTPAARAPGLLTPRPP-----GSPRPPPPVTPAALRVLGA------AGAVGRKPLAE 60 Query: 308 AAQPSQPQGAGPGGQTLP-------PTNV--TLAQPAMSLPPQPGPAVGAPAAQQPQQFA 358 A G GG T+P PT T ++ S PP G AP A+ Sbjct: 61 RA-------GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTS--- 110 Query: 359 YPQPQIPPGHLL------PVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLP 412 P P PG P+ G ++ VA + + S+ A A T+ P Sbjct: 111 -PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP 169 Query: 413 VGTGQNASSVGAQLMGAS---SQPSEAMAPR---TGPAQGGQVAPCQPTGVP-------P 459 GT A + ++ G +P+ + PR GP + A T P P Sbjct: 170 -GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 228 Query: 460 ATVGGVVQPCLGPAGAGQPQSVPPPQMGGSG---------PLSAVPGGPHAVVPGVPNVP 510 + GG+ +P + P + G S P P G A+ P P Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288 Query: 511 AAVPAPSVPSVSTTSVTMPNVPAPL-AQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAP 569 AP++ +S++ + P+ A L +Q+ TP S S + LPLAP + SAP Sbjct: 289 RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP 348 Query: 570 TSLPQSDLSQFQTQTQPLVGQVDDTRRKSEP-LPQPPLSLIAENKPVVKPPVADSLANPL 628 SL +Q T + + LP PPLS +A P P +A PL Sbjct: 349 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA---LPPL 405 Query: 629 QLTPMNSLATSVFSIAIP 646 Q P + + +A P Sbjct: 406 QAPPSPPASPPLSPLATP 423 Score = 69.3 bits (168), Expect = 1e-11 Identities = 84/287 (29%), Positives = 104/287 (36%), Gaps = 46/287 (16%) Query: 238 PESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPG 297 P S SL A PP + P + P S S P PPP+ Q + P P P Sbjct: 466 PPSQAPPSLAA----PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521 Query: 298 AATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQF 357 A P P+ A PS P + PG P+ P + PPQ P + AP Q P Sbjct: 522 ALATP-PLQAL--PS-PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP--- 574 Query: 358 AYPQPQIPPGHLLPVQP-------SGQSEYLQQHVAGLQPPSPAQ-PSSTGAAASPATAA 409 P P P P +P S L +A PP P++ PSST + A Sbjct: 575 --PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA--- 629 Query: 410 TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPC 469 G +A+S +L G S P A P ++A C P A G P Sbjct: 630 ----GHSSSATSTPEELRGYDSGPEGGAA--ASPPPDAELAACHPA----AWSRGPAPPL 679 Query: 470 LGPAGAGQPQSVPPPQMGGS-----------GPLSAVPGGPHAVVPG 505 G P PP GS GP SA P P A+ PG Sbjct: 680 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP-APGALDPG 725 Score = 40.4 bits (93), Expect = 0.006 Identities = 72/279 (25%), Positives = 91/279 (32%), Gaps = 64/279 (22%) Query: 81 PGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLA 140 P +P L L A + PA+ G + S LA AP A Q+ Sbjct: 515 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 574 Query: 141 GSS-AGPVTAAPSQPPT-----TCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSV 194 S A P AP +PPT + S + L G P R S SS Sbjct: 575 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR------------SPSST 622 Query: 195 LTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPP 254 L+ D HSS+ T E G + GPE G A + PP Sbjct: 623 LS-GPDLAGHSSSATSTPEELRGYDS----------------GPEGG------AAASPPP 659 Query: 255 SEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPP--FPGAATGPQPMMAAAQPS 312 +++ PA A S P PP F GA P P A P Sbjct: 660 DAELAACHPA---------------------AWSRGPAPPLAFRGAPGAPLPWPPATGPG 698 Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAA 351 G +T P + T A A+ P PG + G AA Sbjct: 699 SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 737 Score = 33.5 bits (75), Expect = 0.78 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Query: 98 AAAPANGGGVVSARSVSGALASTLAAAATS-APAPGAPGGPQLAGSSAGPVTAAPSQ 153 A P + G+ + G ++T A A P+PG GG AG+ AG + +P Q Sbjct: 694 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 750 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 90.9 bits (224), Expect = 4e-18 Identities = 127/491 (25%), Positives = 165/491 (33%), Gaps = 57/491 (11%) Query: 107 VVSARSVSGALASTLAAAA---TSAPAPGAPGGP-----QLAGSSAGPVTAAPS---QPP 155 V ++ S L+A A TS P PG P + AG+ G APS +PP Sbjct: 133 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192 Query: 156 TTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERD 215 T + +H + EP R R S L R SS ++ Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAAR-------RRPSAGGGLQRPASRSLSSSATPLSSPAR 245 Query: 216 SGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVS--QLPPSEKMSQPTPAQPQSFSVGQ 273 SG A G AH P L A+ Q+ P K + P S + Sbjct: 246 SGPSARG-------TPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297 Query: 274 PQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQ 333 P P PP SAP P T P P A PSQ G TL T+ L Sbjct: 298 PSPSAPP------SPSAP----PSLQTLPSP--PATPPSQAT-TSLGSPTLQATHSFLPS 344 Query: 334 PAMSL----PPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQ 389 P +S PPQ PA+ P Q P P P P P+ + +L Q Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404 Query: 390 PPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQV 449 P P Q + A+ P + + P + + + S S M+P P Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP------ 458 Query: 450 APCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNV 509 P PP +Q P A + PP Q S P S P + +P Sbjct: 459 ----PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 514 Query: 510 PAAVPAPSVPSVSTTSVTM--PNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHS 567 P A P P P V + P+ PA TP +S + L LAPG Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574 Query: 568 APTSLPQSDLS 578 P+ P S LS Sbjct: 575 PPSRSPSSTLS 585 Score = 72.0 bits (175), Expect = 2e-12 Identities = 144/574 (25%), Positives = 190/574 (33%), Gaps = 86/574 (14%) Query: 76 GDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAA----TSAPAP 131 G P V+P L ++ AA A A + GA A A TS P Sbjct: 31 GSPRPPPPVTPAAL---RVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPA 87 Query: 132 GAPG--GPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERD 189 G P +S GPV++ TT L + E RG+ T E +R Sbjct: 88 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT--EAPKR- 144 Query: 190 SDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAV 249 S A RD+ G T G+ +A A G E G + Sbjct: 145 ----------------SALSAGARRDTS-GPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 187 Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPP---PPVGGAVAQ------SSAPLPPFPGAAT 300 PP+E + + + S +P P P GG + + SS+ P A + Sbjct: 188 RPRPPTEG-PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246 Query: 301 GPQPMMAAAQPSQPQGAGPGG-QTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAY 359 GP P+ P P G Q L P VT P P GP +P A P A Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVT--PPRKDAAPALGPLSSSPLAT-PSPSAP 303 Query: 360 PQPQIPPG-HLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQN 418 P P PP LP P+ PPS A +S G+ AT + LP Sbjct: 304 PSPSAPPSLQTLPSPPA-------------TPPSQAT-TSLGSPTLQATHSFLPSPPLSP 349 Query: 419 ASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQP 478 ++ Q + P+ A+ P P P P P + L A P Sbjct: 350 LATPPPQ-----APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQS 538 S PP Q S P S P V + PS S + + P+P A Sbjct: 405 PS-PPVQAPFSPPAS-------------PPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 450 Query: 539 QQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKS 598 S TP ++ + L LA AP +L L + GQ + S Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--PS 508 Query: 599 EPLPQPPLSLIAENKPVVKPPVADSLANPLQLTP 632 LP PL+ P PPV LA PL P Sbjct: 509 ASLPMSPLA----TPPPQAPPV---LAAPLLQVP 535 Score = 69.3 bits (168), Expect = 1e-11 Identities = 84/287 (29%), Positives = 104/287 (36%), Gaps = 46/287 (16%) Query: 238 PESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPG 297 P S SL A PP + P + P S S P PPP+ Q + P P P Sbjct: 427 PPSQAPPSLAA----PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482 Query: 298 AATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQF 357 A P P+ A PS P + PG P+ P + PPQ P + AP Q P Sbjct: 483 ALATP-PLQAL--PS-PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP--- 535 Query: 358 AYPQPQIPPGHLLPVQP-------SGQSEYLQQHVAGLQPPSPAQ-PSSTGAAASPATAA 409 P P P P +P S L +A PP P++ PSST + A Sbjct: 536 --PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA--- 590 Query: 410 TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPC 469 G +A+S +L G S P A P ++A C P A G P Sbjct: 591 ----GHSSSATSTPEELRGYDSGPEGGAA--ASPPPDAELAACHPA----AWSRGPAPPL 640 Query: 470 LGPAGAGQPQSVPPPQMGGS-----------GPLSAVPGGPHAVVPG 505 G P PP GS GP SA P P A+ PG Sbjct: 641 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP-APGALDPG 686 Score = 40.4 bits (93), Expect = 0.006 Identities = 72/279 (25%), Positives = 91/279 (32%), Gaps = 64/279 (22%) Query: 81 PGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLA 140 P +P L L A + PA+ G + S LA AP A Q+ Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535 Query: 141 GSS-AGPVTAAPSQPPT-----TCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSV 194 S A P AP +PPT + S + L G P R S SS Sbjct: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR------------SPSST 583 Query: 195 LTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPP 254 L+ D HSS+ T E G + GPE G A + PP Sbjct: 584 LS-GPDLAGHSSSATSTPEELRGYDS----------------GPEGG------AAASPPP 620 Query: 255 SEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPP--FPGAATGPQPMMAAAQPS 312 +++ PA A S P PP F GA P P A P Sbjct: 621 DAELAACHPA---------------------AWSRGPAPPLAFRGAPGAPLPWPPATGPG 659 Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAA 351 G +T P + T A A+ P PG + G AA Sbjct: 660 SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 698 Score = 33.5 bits (75), Expect = 0.78 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Query: 98 AAAPANGGGVVSARSVSGALASTLAAAATS-APAPGAPGGPQLAGSSAGPVTAAPSQ 153 A P + G+ + G ++T A A P+PG GG AG+ AG + +P Q Sbjct: 655 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 711 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 88.2 bits (217), Expect = 3e-17 Identities = 151/596 (25%), Positives = 201/596 (33%), Gaps = 110/596 (18%) Query: 107 VVSARSVSGALASTLAAAA---TSAPAPGAPGGP-----QLAGSSAGPVTAAPS---QPP 155 V ++ S L+A A TS P PG P + AG+ G APS +PP Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201 Query: 156 TTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERD 215 T + +H + EP R R S L R SS ++ Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAAR-------RRPSAGGGLQRPASRSLSSSATPLSSPAR 254 Query: 216 SGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVS--QLPPSEKMSQPTPAQPQSFSVGQ 273 SG A G AH P L A+ Q+ P K + P S + Sbjct: 255 SGPSARG-------TPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306 Query: 274 PQP------PPPPVGGAVAQSSAPLPPFPGAATGPQPMMA----------------AAQP 311 P P P PP A A LPP P AT P P+ A P Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLAT-PLPLAPPSPSAPPSLQTLPSPPATPP 365 Query: 312 SQ--------PQGAGPGGQTLPPTNV--TLAQPAMSLPPQP--------GPAVGAPAAQQ 353 SQ P A P QT+PP V +L P++ PP P ++G+P Q Sbjct: 366 SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA 425 Query: 354 PQQFAYPQPQIPPGHLL----PVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAA 409 F P+ L P S LQ ++ P SP +S A SP ++ Sbjct: 426 THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS--LPASPPLQTSLSPAVSP-LSS 482 Query: 410 TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPT-GVPPATVGGVVQP 468 L + Q SS+ AS P ++ P Q + P+ PPA++ Sbjct: 483 PLTIHPLQALSSL------ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL------ 530 Query: 469 CLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTM 528 P P PPP S PL+ PH P P P + AP P + T Sbjct: 531 -TTPPLENLPSLAPPPLQTASAPLTT----PHLETPPCP-APCPLQAPPSPLTTPPPETP 584 Query: 529 PNVPAPLAQSQQLSSHTPVSRSSS------------IIQHVGLPLAPGTHSAPTSLPQSD 576 ++ P Q+ + P+ S + LP S P S P S Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644 Query: 577 LSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTP 632 L+ Q P V + P P PP+ A P PPV+ S P Q P Sbjct: 645 LATPSPQA-PNALAVHLLQAPFSPPPSPPVQ--APFSPPASPPVSPSATPPSQAPP 697 Score = 77.8 bits (190), Expect = 4e-14 Identities = 111/418 (26%), Positives = 148/418 (35%), Gaps = 87/418 (20%) Query: 231 SMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPP--------PPPVG 282 S +H P++ S + +PP E S P Q+ PP PPP+ Sbjct: 493 SSLASHSPQAPLSSLI-----MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ 547 Query: 283 GAVAQSSAP--------------LPPFPGAATGPQ-PMMAAAQPSQ--PQGAGPGGQTLP 325 A A + P PP P P+ P A P Q P A P Q LP Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607 Query: 326 PTNVTLAQPAMSLPPQPGPAVGAPAAQQP---------QQFAYPQPQIPPG---HLL--P 371 ++ P + PPQ P + P Q P A P PQ P HLL P Sbjct: 608 SPPLS---PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664 Query: 372 VQPSGQSEYLQQHVAGLQPPS--PAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGA 429 P S +Q A PP+ P PS+T + +P + A P+ + + + + Sbjct: 665 FSPP-PSPPVQ---APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA-SPPMSPS 719 Query: 430 SSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPP------ 483 ++ P +A P P QV P P PP + P + P A P VPP Sbjct: 720 ATPPPQAPPPLAAPPL--QVPPSPPAS-PPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776 Query: 484 ------------PQMGGSGPLSAVPGGPHAVVPG---------VPNVPAAVPAPSVPSVS 522 P + PL A+P P A PG +P P A P P P V Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALP-SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835 Query: 523 TTSVTM--PNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLS 578 + P+ PA TP +S + L LAPG P+ P S LS Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 893 Score = 67.8 bits (164), Expect = 4e-11 Identities = 116/474 (24%), Positives = 166/474 (35%), Gaps = 68/474 (14%) Query: 212 AERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSV 271 AER G+G + S A S SS S+ P S + + PA+ + S Sbjct: 59 AERAGGIGGA-----TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK--NTSP 111 Query: 272 GQPQPP--------PPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQT 323 G P P P+G + SA G AT A + ++ +GP T Sbjct: 112 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171 Query: 324 LPP----------TNVTLAQPAMSLPPQP---GPAVGAPAAQQ-----PQQFAYPQPQIP 365 P T V L +PA S P+P GP +A + P A +P Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231 Query: 366 PGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQ 425 G P S L L P+ + PS+ G +PA + + A Sbjct: 232 GGLQRPASRS-----LSSSATPLSSPARSGPSARGTPRAPAHPSQ------PKPKGLQAL 280 Query: 426 LMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQP-QSVPPP 484 + P + AP GP +A P+G +P P A P + PP Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK-------ARPVPPPDNAATPLPATLPP 333 Query: 485 QMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544 + PL P P A P + +P+ P + PS + S+T P + AP + Sbjct: 334 SPPLATPLPLAPPSPSAP-PSLQTLPS--PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390 Query: 545 TPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQP 604 P S +S +Q PLA + A TSL L Q + P Q Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL------------QATHSFLTMSPR-QT 437 Query: 605 PLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTA 658 SL + ++P PP + L PL L L TS+ P+ +P A Sbjct: 438 QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA 491 Score = 62.4 bits (150), Expect = 2e-09 Identities = 82/315 (26%), Positives = 108/315 (34%), Gaps = 66/315 (20%) Query: 253 PPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPS 312 P S + P+ A P + PP PP ++ S+ P P P P + + P+ Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743 Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQ------------------------------- 341 P P P LA P + +PP Sbjct: 744 SPP-MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802 Query: 342 -----PGPAVGAPAAQQPQQ-FAYPQPQIPP---GHLLPVQPSGQSEYLQQHVAGLQPPS 392 PG A +P+A P A P PQ PP LL V PS + Q A +PP+ Sbjct: 803 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ--APRRPPT 860 Query: 393 PAQPSS-TGAAASPATAATLPVGTGQNASSV--GAQLMG----ASSQPSEAMAPRTGPAQ 445 P +S +G + A A P ++ SS G L G A+S P E +GP Sbjct: 861 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 920 Query: 446 GGQVAPCQPTGV----PPATVGGVVQPCLGPAGAGQPQSVPPPQMGGS-----------G 490 G +P + P A G P G P PP GS G Sbjct: 921 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 980 Query: 491 PLSAVPGGPHAVVPG 505 P SA P P A+ PG Sbjct: 981 PESATP-APGALDPG 994 Score = 40.4 bits (93), Expect = 0.006 Identities = 72/279 (25%), Positives = 91/279 (32%), Gaps = 64/279 (22%) Query: 81 PGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLA 140 P +P L L A + PA+ G + S LA AP A Q+ Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 843 Query: 141 GSS-AGPVTAAPSQPPT-----TCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSV 194 S A P AP +PPT + S + L G P R S SS Sbjct: 844 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR------------SPSST 891 Query: 195 LTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPP 254 L+ D HSS+ T E G + GPE G A + PP Sbjct: 892 LS-GPDLAGHSSSATSTPEELRGYDS----------------GPEGG------AAASPPP 928 Query: 255 SEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPP--FPGAATGPQPMMAAAQPS 312 +++ PA A S P PP F GA P P A P Sbjct: 929 DAELAACHPA---------------------AWSRGPAPPLAFRGAPGAPLPWPPATGPG 967 Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAA 351 G +T P + T A A+ P PG + G AA Sbjct: 968 SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 1006 Score = 38.1 bits (87), Expect = 0.032 Identities = 80/319 (25%), Positives = 97/319 (30%), Gaps = 79/319 (24%) Query: 390 PPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQV 449 P SP P AA A VG A G +G ++ P A PR GP + Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG--IGGATIPESA--PRAGPTRSAGT 85 Query: 450 APCQPTGVPPAT----------------------VGGVVQPCLGPAG------------- 474 + P PPA+ G +P GP G Sbjct: 86 SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP--GPLGQKGLRISAEETVA 143 Query: 475 --------------AGQPQSVPPPQMGGSGPLSA--------VPGGPHAVVPGVPNVPAA 512 AG + P G P A G P P P Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203 Query: 513 VPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRS-SSIIQHVGLPL-----APGTH 566 P SV S S S T P+ A S P SRS SS + P A GT Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263 Query: 567 SAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSE----PLPQPPLSLIAENKPVVKP-PVA 621 AP Q Q P QV R+ + PL PL+ + + +P P Sbjct: 264 RAPAHPSQPKPKGLQALRPP---QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP 320 Query: 622 DSLANPLQLT--PMNSLAT 638 D+ A PL T P LAT Sbjct: 321 DNAATPLPATLPPSPPLAT 339 Score = 33.5 bits (75), Expect = 0.78 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Query: 98 AAAPANGGGVVSARSVSGALASTLAAAATS-APAPGAPGGPQLAGSSAGPVTAAPSQ 153 A P + G+ + G ++T A A P+PG GG AG+ AG + +P Q Sbjct: 963 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 87.0 bits (214), Expect = 6e-17 Identities = 136/553 (24%), Positives = 193/553 (34%), Gaps = 58/553 (10%) Query: 38 ESRTEDVSSEIFDVSRATDYGPEE--------VCERSSSEETLNNVGDAETPGTVSPNLL 89 E R D IF + T G E V +R S + V DA SP Sbjct: 798 ERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPE-- 855 Query: 90 LDGQLAAAAAAPANGGGVVSA-----------RSVSGALASTLAAAATSAPAPGAPGGPQ 138 +G AA AP G VV+A S+ + AAA SAP Sbjct: 856 -EGTSIAAVPAP-EGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVT 913 Query: 139 LAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYY----ERDSDSSV 194 ++ AA S P T + I + S W + E D Sbjct: 914 VSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEG 973 Query: 195 LTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGT----DSSLTAVS 250 + D A R S S V + + P + + + A + Sbjct: 974 PVTPATTVHAPEEPDTAAVRVS-TPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1032 Query: 251 QLPPSEKMSQ----PTPAQPQSFSVGQPQPPPPPV-GGAVAQSSAPLPPFPGAATGPQPM 305 PP E S PTP +P S + P P P AV P P T +P Sbjct: 1033 VPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1092 Query: 306 M-AAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQI 364 AAA P+ + P PT A PA ++P PA A A P++ A+P P + Sbjct: 1093 SPAAAVPTPEEPTSPAAAV--PTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150 Query: 365 PPGHLLPVQPSGQSEYLQQHVAGLQP----PSPAQPSSTGAAASPATAATLPVGTGQNAS 420 P P + + + + P P+PA+ +S A + T P + + Sbjct: 1151 P----TPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPA 1206 Query: 421 SVGAQLMGASSQPSEAMAPRTGPAQGGQVA--PCQPTGVPPATVGGVVQPCLGPAGAGQP 478 ++ A L +S P+ ++ PA P +PT P A V + +P A P Sbjct: 1207 AMVATLEEFTS-PAASVPTSEEPASLAAAVSNPEEPTS-PAAAVPTLEEPTSSAAAVLTP 1264 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGV--PNVP-AAVPAPSVPSVSTTSVTMPNVPA-P 534 + + P S P P P A V + P P AAVP P V ++ SV P VPA P Sbjct: 1265 EELSSP--AASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIP 1322 Query: 535 LAQSQQLSSHTPV 547 A + +P+ Sbjct: 1323 AAAVPPMEEVSPI 1335 Score = 64.7 bits (156), Expect = 3e-10 Identities = 92/377 (24%), Positives = 135/377 (35%), Gaps = 51/377 (13%) Query: 270 SVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQP---QGAGPGGQTLPP 326 +V P+ P V A+ Q A G P AA + P + P G P Sbjct: 925 AVSSPEETAPAVAAAITQEGM------SAVAGFSPEWAALAITVPITEEDGTPEGPVTPA 978 Query: 327 TNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVA 386 T V P +P A A P++ A P +P P +P+ + + Sbjct: 979 TTV-------HAPEEPDTA--AVRVSTPEEPASPAAAVPT----PEEPTSPAAAV----- 1020 Query: 387 GLQPPSPAQPSSTGAAASPATAATLP---VGTGQNASSVGAQLMGASSQPSEAMAPRTGP 443 P+P +P+S AA P T P V T + +S A + S A A T P Sbjct: 1021 ----PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT-P 1075 Query: 444 AQGGQVAPCQPTGVPPATVGGVVQPCLGPAG--AGQPQSVPPPQMGGSGPLSAVPGGPHA 501 + A PT P + V P A P P + P P P A Sbjct: 1076 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAA 1135 Query: 502 VVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPL 561 VP P PA PAP+VP+ ++ VP P + ++ + S+S V Sbjct: 1136 AVP-TPEEPA-FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLE 1193 Query: 562 APGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAE-NKPVVKPPV 620 P + +A P + ++ + T P S P + P SL A + P + P Sbjct: 1194 EPTSPAASVPTPAAMVATLEEFTSPAA---------SVPTSEEPASLAAAVSNP--EEPT 1242 Query: 621 ADSLANPLQLTPMNSLA 637 + + A P P +S A Sbjct: 1243 SPAAAVPTLEEPTSSAA 1259 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 86.3 bits (212), Expect = 1e-16 Identities = 160/664 (24%), Positives = 227/664 (34%), Gaps = 136/664 (20%) Query: 214 RDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKM-------SQPTPAQP 266 R + GA G VV + GP + + + A + PP+ + +P P P Sbjct: 51 RAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSP 110 Query: 267 QSFSV-GQPQPP-----PPPVGGA-----------VAQSSAPLPPFPGAATGPQPMMAAA 309 + V P PP PPP G A VA P P P GP + A A Sbjct: 111 RRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170 Query: 310 QPSQPQGAGPG-------------GQTLPPTNVTL-----AQPAMSL------------- 338 P G GPG QTL + L A PA+SL Sbjct: 171 GPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK 230 Query: 339 PPQPG------PAVGA-----------PAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYL 381 P PG P VGA PAA P A P PP +P G Sbjct: 231 PAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP 290 Query: 382 QQHVAGLQPPSPAQ-PSSTGAAASPATAATLPVG-TGQNASSVGAQLMGASSQPSEAMAP 439 + PP+ AQ S GAA +PA AA P G +GQ A A + +A +P Sbjct: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAA---AAPAPGVKAESP 347 Query: 440 RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAG---QPQSVPPPQMGGSGPLSAVP 496 + A P +T +V +GP G P +VPPP G P Sbjct: 348 KRVVQAAPPAAQTLAASGPASTAASMV---IGPTMQGALPSPAAVPPPAPG--TPTGLPK 402 Query: 497 GGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQH 556 G AV + P A + + + T +V P +P P ++ + IQ+ Sbjct: 403 GAAGAVTQSLSRTPTATTS-GIRATLTPTVLAPRLPQP-------------PQNPTNIQN 448 Query: 557 VGLP----LAPGTHSAPTSLPQSDLSQFQTQ--TQPLVGQVDDTRRKSEPLPQPPLSLIA 610 LP L + +PQ L+Q Q Q QP Q R + P PP+ + Sbjct: 449 FQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQP---QTTMAPRPATPTSAPPVQIST 505 Query: 611 ENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTAF---YQAFHLNT 667 P P+ P + S A + + + P Q L T Sbjct: 506 VQAP--GTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGT 563 Query: 668 LKESKSLWDSASGGGVVAIDNKIEQAMDLVKS---------HLMYAVREEVEVLKEQIKE 718 ++ + G + + M+ VK L + ++ E +KE Sbjct: 564 ATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTET-AANVKE 622 Query: 719 LVER--NSLLERE---NALLKSLSSNDQLSQLP--------TQQANPGSTSQQQAVIAQP 765 LV+ + +E E + L + L+S+ Q +P +Q P S + Q QP Sbjct: 623 LVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQP 682 Query: 766 PQPT 769 P PT Sbjct: 683 PPPT 686 Score = 38.5 bits (88), Expect = 0.024 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 5/86 (5%) Query: 78 AETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGP 137 AE+P V Q AA+ + +V ++ GAL S AA PAPG P G Sbjct: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSP---AAVPPPAPGTPTG- 399 Query: 138 QLAGSSAGPVTAAPSQPPTTCSSRFR 163 L +AG VT + S+ PT +S R Sbjct: 400 -LPKGAAGAVTQSLSRTPTATTSGIR 424 Score = 36.2 bits (82), Expect = 0.12 Identities = 58/231 (25%), Positives = 78/231 (33%), Gaps = 33/231 (14%) Query: 427 MGASSQPSEAMAPRTGP---AQGGQVAPCQPTGVPPATVG-GVVQPCLG-PAGAGQPQSV 481 + AS+ +APRT A G + +G P G G P G P A +P Sbjct: 33 LAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPA 92 Query: 482 PPPQMGGSGPLSAVPGGPHA---VVPGVPNVPAA-------------VPAPSVPSVSTTS 525 + GG GP PG P +VP P PAA P P+ +V+ Sbjct: 93 GRARPGGGGPQR--PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGP 150 Query: 526 VTMPNVPA----PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQ 581 P PA P A + + G P PG +A T + L Sbjct: 151 EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPG--AAQTLNGSAALLNSH 208 Query: 582 TQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTP 632 P V V++ PLP+P A + PP + A P P Sbjct: 209 HAAAPAVSLVNNGPAALLPLPKP----AAPGTVIQTPPFVGAAAPPAPAAP 255 Score = 34.3 bits (77), Expect = 0.46 Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 3/64 (4%) Query: 96 AAAAAPANGGGVVSARSVSGA---LASTLAAAATSAPAPGAPGGPQLAGSSAGPVTAAPS 152 AAAAAPA G S + V A A TLAA+ ++ A GP + G+ P P Sbjct: 333 AAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPP 392 Query: 153 QPPT 156 P T Sbjct: 393 APGT 396 Score = 32.0 bits (71), Expect = 2.3 Identities = 67/277 (24%), Positives = 92/277 (33%), Gaps = 40/277 (14%) Query: 81 PGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPG-GPQL 139 P P +G A AA APA G +G AA +APAPG P+ Sbjct: 295 PAVPPPAAAQNGGSAGAAPAPAPAAG-----GPAGVSGQPGPGAAAAAPAPGVKAESPKR 349 Query: 140 AGSSAGPV--TAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTR 197 +A P T A S P +T +S + P + + + + Sbjct: 350 VVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSP------AAVPPPAPGTPTGLPKG 403 Query: 198 SGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEK 257 + + S + TA SG+ AT V+ Q P + + L L SE Sbjct: 404 AAGAVTQSLSRTPTA-TTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSEN 462 Query: 258 -----MSQPTPAQPQSFSVGQPQ------PPPPPVGGAVAQSSAPLPPFPGAATGPQPMM 306 + Q AQ Q+ + QPQ P P V S+ P P A P Sbjct: 463 GQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTT 522 Query: 307 AAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPG 343 Q SQ Q T QP+ +L PG Sbjct: 523 IIKQVSQAQ--------------TTVQPSATLQRSPG 545 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 83.2 bits (204), Expect = 9e-16 Identities = 142/555 (25%), Positives = 199/555 (35%), Gaps = 89/555 (16%) Query: 247 TAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMM 306 TA+ Q PP + P P G P PPP P G + PLPP PGA P P + Sbjct: 894 TAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL-----PLPPLPGAGIPPPPPL 948 Query: 307 AAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPP 366 A P G LPP P PP P P G P P P P Sbjct: 949 PGAAIPPPPPLPGAGIPLPPPLPGAGIP----PPPPLPGAGIPPPPPLPGAGIPPPPPLP 1004 Query: 367 GHLLPVQP----SGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSV 422 G +P P +G AG+ PP P P + P A +P + + Sbjct: 1005 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGI 1063 Query: 423 --GAQLMGASSQPSE----AMAPRTGPAQGGQVAPCQP-TGV----PPATVGGVVQPCLG 471 L GA P A P P G + P P GV PP G + P Sbjct: 1064 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1123 Query: 472 PAGAGQPQSVPPPQMGGSG-----PLSAV-----PGGPHAVVPGVPNVPAA--VPAPSVP 519 GAG P PPP + G+G PL V P P A +P P +P A P P +P Sbjct: 1124 LPGAGIP---PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1180 Query: 520 SVS-TTSVTMPNV---PAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAP--TSLP 573 V +P V P P + P + +G+P AP P T +P Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLPGAGIPPPPP-------LPGMGIPPAPAPPLPPPGTGIP 1233 Query: 574 QSDLSQFQTQTQPLVGQVDDTRRKSEPLPQ------PPLSL----------IAENKPVVK 617 L PL+ QV + + P PQ PPL K ++ Sbjct: 1234 PPPL--LPVSGPPLLPQVGSS---TLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIE 1288 Query: 618 P--PVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTLKESK--- 672 P P+ +QL +TS+ I +E F + F +KE K Sbjct: 1289 PCRPMKPLYWTRIQLHSKRDSSTSLIWEKI----EEPSIDCHEFEELFSKTAVKERKKPI 1344 Query: 673 --SLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLEREN 730 ++ + + V + NK QA+ ++ S L +++ + +V+ LE Sbjct: 1345 SDTISKTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVD----LETLQ 1400 Query: 731 ALLKSLSSNDQLSQL 745 AL ++ + +D+L ++ Sbjct: 1401 ALYENRAQSDELEKI 1415 Score = 65.1 bits (157), Expect = 2e-10 Identities = 84/318 (26%), Positives = 109/318 (34%), Gaps = 91/318 (28%) Query: 254 PSEKMSQPTPAQPQSFSVGQPQ-------------------------------PPPPPVG 282 P++ +SQP P +S GQ Q P PPP+ Sbjct: 803 PTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862 Query: 283 GAVAQSS--------APLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQP 334 + SS P PP PG P A QP QG + LPP Sbjct: 863 CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT----EMLPP-------- 910 Query: 335 AMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPA 394 PP P P G P P P +P +LP+ P AG+ PP P Sbjct: 911 ----PPPPLPGAGIP----------PPPPLPGAGILPLPPLPG--------AGIPPPPPL 948 Query: 395 QPSSTGAAASPATAATLPVGTGQNASSV--GAQLMGASSQPSE----AMAPRTGPAQGGQ 448 P + P A +P+ + + L GA P A P P G Sbjct: 949 -PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1007 Query: 449 VAPCQP---TGV--PPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVV 503 + P P G+ PP G + P GAG P PPP + G+G + P P A + Sbjct: 1008 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLPGAG-IPPPPPLPGAGI 1063 Query: 504 PGVPNVPAA--VPAPSVP 519 P P +P A P P +P Sbjct: 1064 PPPPPLPGAGIPPPPPLP 1081 Score = 65.1 bits (157), Expect = 2e-10 Identities = 74/277 (26%), Positives = 100/277 (36%), Gaps = 37/277 (13%) Query: 253 PPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPS 312 PP ++ + + P +G PPPPP+ G +P P A P + + Sbjct: 858 PPPLPCTESSSSMP---GLGMVPPPPPPLPGMT------VPTLPSTAIPQPPPLQGTEML 908 Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPV 372 P G +PP + LPP PG G P A P P PG +P+ Sbjct: 909 PPPPPPLPGAGIPPPPPLPGAGILPLPPLPG--AGIPPPPPLPGAAIPPPPPLPGAGIPL 966 Query: 373 QPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSV--GAQLMGAS 430 P AG+ PP P P + P A +P + + L GA Sbjct: 967 PPPLPG-------AGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1018 Query: 431 SQPSE----AMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQM 486 P A P P G + P PP G + P GAG P PPP + Sbjct: 1019 IPPPPPLPGAGIPPPPPLPGAGIPP------PPPLPGAGIPPPPPLPGAGIP---PPPPL 1069 Query: 487 GGSGPLSAVPGGPHAVVPGVPNVPAA--VPAPSVPSV 521 G+G + P P A +P P +P A P P +P V Sbjct: 1070 PGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1105 Score = 52.0 bits (123), Expect = 2e-06 Identities = 52/165 (31%), Positives = 54/165 (32%), Gaps = 20/165 (12%) Query: 246 LTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPL------PPFPGAA 299 L V PP P P G P PPP P G P PP PGA Sbjct: 1102 LPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG 1161 Query: 300 -TGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSL------PPQPGPAVGAPAAQ 352 P P+ A P P G G PP P L PP P P +G P A Sbjct: 1162 IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP 1221 Query: 353 QPQQFAYPQPQIPPGHLLPVQ------PSGQSEYLQQHVAGLQPP 391 P P IPP LLPV G S V G PP Sbjct: 1222 AP-PLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPP 1265 Score = 40.4 bits (93), Expect = 0.006 Identities = 33/102 (32%), Positives = 37/102 (36%), Gaps = 7/102 (6%) Query: 246 LTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPM 305 L V PP P P G P PPP P G + PLPP PG P P+ Sbjct: 1179 LPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP-PGTGIPPPPL 1237 Query: 306 MAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVG 347 + + P P G TLP V P PP P G Sbjct: 1238 LPVSGP--PLLPQVGSSTLPTPQVCGFLP----PPLPSGLFG 1273 Score = 36.2 bits (82), Expect = 0.12 Identities = 71/282 (25%), Positives = 99/282 (35%), Gaps = 68/282 (24%) Query: 242 TDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAP-LP------- 293 T+ +L+A+S LP S A+P+ +P PP G + S AP LP Sbjct: 269 TEQALSALSDLPES------LAAEPR-------EPQQPPSPGGLPVSEAPSLPAAQPAAK 315 Query: 294 --------PFPGAATGPQ----PMMAAAQPSQ----------PQGAGPGGQTLPPTNVTL 331 PFP A G + P+ A + P+G+ PG + P Sbjct: 316 DSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGS-PGEEWAPEVGEDA 374 Query: 332 AQPAMSLPPQPGPAVGAPAAQQ------PQQFAY-PQPQIPPGHL--------LPVQPSG 376 Q P + APAA P Q + P P I P ++ P Sbjct: 375 PQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPS 434 Query: 377 QSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEA 436 QS + PS ++ S T A+ A A G A + S+ +E Sbjct: 435 QSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAG------LSRSADWTEE 488 Query: 437 MAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQP 478 + RT P GG A GV + GG V P L +G P Sbjct: 489 LGART-PRVGGS-AHLLERGV-ASDSGGGVSPALAAKASGAP 527 Score = 32.3 bits (72), Expect = 1.7 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 18/129 (13%) Query: 256 EKMSQPTPAQPQSFS-VGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQP 314 E + PT PQ + +G + P GGA +P +A P AA+P +P Sbjct: 231 EPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREP 290 Query: 315 -QGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL---L 370 Q PGG LP + P++ PA A P A+P P+ PG Sbjct: 291 QQPPSPGG--LPVSEA----PSL-------PAAQPAAKDSPSSTAFPFPEAGPGEEAAGA 337 Query: 371 PVQPSGQSE 379 PV+ +G ++ Sbjct: 338 PVRGAGDTD 346 Score = 30.0 bits (66), Expect = 8.6 Identities = 30/115 (26%), Positives = 42/115 (36%), Gaps = 14/115 (12%) Query: 491 PLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRS 550 P+ +PG P P P A P S S+ + +P S QL SH P Sbjct: 759 PVDGLPGRP-------PCPPGAESGPQTKFCSEISL----IVSPRRISVQLDSHQPTQSI 807 Query: 551 SSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPP 605 S L + G + P S ++FQT + V + S +P PP Sbjct: 808 SQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHE---HSVSSAFKNSCNIPSPP 859 >gi|62865625 TSC22 domain family, member 3 isoform 3 [Homo sapiens] Length = 77 Score = 81.3 bits (199), Expect = 3e-15 Identities = 46/88 (52%), Positives = 58/88 (65%), Gaps = 14/88 (15%) Query: 694 MDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQANPG 753 MDLVK+HLMYAVREEVE+LKEQI+ELVE+NS LEREN LLK+L+S +QL + Sbjct: 1 MDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKF-------- 52 Query: 754 STSQQQAVIAQPPQPTQP--PQQPNVSS 779 Q + + P P P P+ P S+ Sbjct: 53 ----QSCLSPEEPAPESPQVPEAPGGSA 76 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 79.0 bits (193), Expect = 2e-14 Identities = 106/409 (25%), Positives = 150/409 (36%), Gaps = 54/409 (13%) Query: 251 QLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQ 310 Q PP+ +S P P Q QP P P A Q++ P P PG A+ P+ ++ Sbjct: 626 QAPPA--VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLASSPEKIVLGQP 682 Query: 311 PSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLL 370 PS P +T M LP + +QQP P +P ++ Sbjct: 683 PS----------ATPTAILTQDSLQMFLPQE--------RSQQPLSAEGPHLSVPASVIV 724 Query: 371 PVQPSGQSEYLQQHV---AGLQPPSP-AQPSSTGAAASPATAATLPVGTGQNASSVGAQL 426 P Q V AGL P +P +Q S A PA A G + S Sbjct: 725 SAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAP 784 Query: 427 MGAS---SQPSEAMAPRTGPAQGGQVA---------PCQPTGVPPATVG-GVVQPCLG-- 471 +G S P P P++ V+ PC P PP G V+Q LG Sbjct: 785 LGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP 844 Query: 472 PAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNV 531 P + + P P P S P GP +P P++P P+ + +V+++S T + Sbjct: 845 PPASNPAPTAPGPPQPPLRPQSQPPEGP---LPPAPHLP---PSSTSSAVASSSETSSRL 898 Query: 532 PAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQV 591 PAP QL S L L P + P P++ FQ T P + Sbjct: 899 PAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRT----FQMVTTPFPA-L 953 Query: 592 DDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSV 640 + E Q P +I +NK P + + L P+ S A SV Sbjct: 954 PQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTS---LGPLTSPAASV 999 Score = 69.3 bits (168), Expect = 1e-11 Identities = 129/523 (24%), Positives = 182/523 (34%), Gaps = 78/523 (14%) Query: 114 SGALASTLAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGE 173 +G + + APA A Q ++ G AAP QPP S V L+ GS Sbjct: 402 AGKAGQNVVLSGFPAPALQANVFKQPPATTTG---AAPPQPPGALSKPMSVHLLNQGSSI 458 Query: 174 PYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQ 233 +L + + Q ++ S L A G ++ A+ Sbjct: 459 VIPA--------------QHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAA-- 502 Query: 234 GAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLP 293 P +G QL + ++ A P S+G P A S+AP+ Sbjct: 503 ----PHTG--------GQLIANPILTNQNLAGP--LSLGPVLAPHSGAHSAHILSAAPIQ 548 Query: 294 PF-PGAATGPQPMMAAAQP--SQPQGAGPG------GQTLPPTNVTLAQPAMSLPPQPGP 344 P P + A + P SQP AGP G TLPP+ V + L QP Sbjct: 549 VGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLV-QPAT 607 Query: 345 AVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAAS 404 A P P PQ PP P+ Q QQ P + A P +T S Sbjct: 608 PAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPS 667 Query: 405 PATAAT-LPVGTGQNASSVGAQLM-----------GASSQPSEAMAPRTGPAQGGQVAPC 452 P A++ + GQ S+ ++ S QP A P + Sbjct: 668 PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLS-VPASVIVSA 726 Query: 453 QPTGVPPATVGGVVQPC-LGP-AGAGQPQSVPPPQMGGSGPL-----SAVPGGPH-AVVP 504 P PA V + LGP A Q P PQ+ + PL S+ P PH A + Sbjct: 727 PPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLG 786 Query: 505 GVPNVPAAVPA--PSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLA 562 P++P+ P PS P SV+ P PL + + I +G+P Sbjct: 787 DSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP-P 845 Query: 563 PGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPP 605 P ++ APT+ P + Q+QP G PLP P Sbjct: 846 PASNPAPTA-PGPPQPPLRPQSQPPEG----------PLPPAP 877 Score = 58.9 bits (141), Expect = 2e-08 Identities = 89/361 (24%), Positives = 128/361 (35%), Gaps = 64/361 (17%) Query: 227 VVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVA 286 V+V++ A P T + A L P SQ +PA P P P Sbjct: 722 VIVSAPPPAQDPAPATPVAKGA--GLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSL 779 Query: 287 QSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTL--AQPAMSLPPQPGP 344 APL P + + PS+PQ + PP+ L P + P PG Sbjct: 780 PHQAPLGDSPHLPSPHPTRPPSRPPSRPQSV-----SRPPSEPPLHPCPPPQAPPTLPGI 834 Query: 345 AVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQP---SSTGA 401 V P + P P P P++P Q G PP+P P +S+ Sbjct: 835 FVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPP------EGPLPPAPHLPPSSTSSAV 888 Query: 402 AASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPAT 461 A+S T++ LP T PS+ + P+QG +P PP T Sbjct: 889 ASSSETSSRLPAPT-----------------PSDFQL-QFPPSQGPHKSP-----TPPPT 925 Query: 462 VGGVVQPCLGPAGAGQPQSVPPPQ--MGGSGPLSAVPGGPHAVVPGVPNVPAAV------ 513 + V +P P PPP+ + P A+P P A++ VP+ + Sbjct: 926 LHLVPEPAAPPP--------PPPRTFQMVTTPFPALP-QPKALLERFHQVPSGIILQNKA 976 Query: 514 -PAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSL 572 AP+ P ST+ + + A + S Q S TP + S H P P L Sbjct: 977 GGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPS-----HAPAPAPMAATGLPPLL 1031 Query: 573 P 573 P Sbjct: 1032 P 1032 Score = 58.2 bits (139), Expect = 3e-08 Identities = 79/288 (27%), Positives = 104/288 (36%), Gaps = 52/288 (18%) Query: 253 PPSEKMSQPT-----PAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMA 307 PPS S+P P++P PQ PP G V Q+ +PP P + P Sbjct: 799 PPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP-PASNPAPTAPGP 857 Query: 308 AAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP----- 362 P +PQ P G LP PA LPP + A +++ + P P Sbjct: 858 PQPPLRPQSQPPEG-PLP--------PAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQL 908 Query: 363 QIPPG---HLLPVQPSGQSEYLQQHVAGLQPPSPA--QPSSTGAAASPATAATL------ 411 Q PP H P P + +L A PP P Q +T A P A L Sbjct: 909 QFPPSQGPHKSPTPP--PTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQV 966 Query: 412 PVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLG 471 P G + GA A+ Q S ++ P T PA V+ P+G P A P Sbjct: 967 PSGIILQNKAGGAP---AAPQTSTSLGPLTSPAASVLVSGQAPSGTPTA-------PSHA 1016 Query: 472 PAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVP 519 PA P M +G +P A +P + A A S P Sbjct: 1017 PA---------PAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055 Score = 57.4 bits (137), Expect = 5e-08 Identities = 68/240 (28%), Positives = 86/240 (35%), Gaps = 50/240 (20%) Query: 226 VVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAV 285 + V+ + G P S + Q PP SQP P+ P PP AV Sbjct: 834 IFVIQNQLGVPPPASNPAPTAPGPPQ-PPLRPQSQP----PEGPLPPAPHLPPSSTSSAV 888 Query: 286 AQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGP- 344 A SS P A P PSQ GP PP + L P + PP P P Sbjct: 889 ASSSETSSRLP--APTPSDFQLQFPPSQ----GPHKSPTPPPTLHLV-PEPAAPPPPPPR 941 Query: 345 -----AVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSST 399 PA QP+ Q+P G +L Q+ AG P +P +S Sbjct: 942 TFQMVTTPFPALPQPKALLERFHQVPSGIIL------------QNKAGGAPAAPQTSTSL 989 Query: 400 GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPP 459 G SPA + + +GQ S G + PS A AP AP TG+PP Sbjct: 990 GPLTSPAASVLV---SGQAPS-------GTPTAPSHAPAP----------APMAATGLPP 1029 Score = 51.6 bits (122), Expect = 3e-06 Identities = 111/469 (23%), Positives = 156/469 (33%), Gaps = 97/469 (20%) Query: 234 GAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPP----------PPPVGG 283 G G G D + Q +++ T +G Q P P GG Sbjct: 89 GGGGGSGGADQPCDILQQSLQEANITEQTLEAEAELDLGPFQLPTLQPADGGAGPTGAGG 148 Query: 284 AVAQSSAPLPPFPG-----------------AATGPQPMMAAAQPSQP--QGAGPGGQTL 324 A A ++ P FPG A PQ ++ A QP Q G G TL Sbjct: 149 AAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTL 208 Query: 325 PP---------------TNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P T TL + + QP A+ P +Q + Q+P Sbjct: 209 QPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAK------QVPVSGY 262 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPAT------------AATLPVGTGQ 417 L +G SE + AG+ P +A+ AT AA+ P GT Sbjct: 263 L-ASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPS 321 Query: 418 NASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ--PTGVPPATVGGVVQPCLGPAGA 475 G L A S + P P Q P GV P + + PAGA Sbjct: 322 -----GQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGA 376 Query: 476 -----GQPQSVP--PPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTM 528 G+P ++P P ++A G + V+ G P P +TT Sbjct: 377 TLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAP 436 Query: 529 PNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTS----LPQSDLSQFQTQT 584 P P L S+ +S H +++ SSI+ P H P LP + Q Q Sbjct: 437 PQPPGAL--SKPMSVHL-LNQGSSIV-------IPAQHMLPGQNQFLLPGAPAVQLPQQL 486 Query: 585 QPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPM 633 L V + + P LIA P++ +LA PL L P+ Sbjct: 487 SALPANVGG-QILAAAAPHTGGQLIA--NPIL---TNQNLAGPLSLGPV 529 Score = 38.9 bits (89), Expect = 0.019 Identities = 50/205 (24%), Positives = 66/205 (32%), Gaps = 44/205 (21%) Query: 230 ASMQGAHGPESGTDSSLTAVS------QLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGG 283 +S A S T S L A + Q PPS+ + P V +P PPPP Sbjct: 882 SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPR 941 Query: 284 AVAQSSAPLPPFP-----------------------GAATGPQ------PMMAAAQPSQP 314 + P P P GA PQ P+ + A Sbjct: 942 TFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLV 1001 Query: 315 QGAGPGGQTLPPTNVTLAQP--AMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPV 372 G P G P++ P A LPP A A+ P PG Sbjct: 1002 SGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPG----- 1056 Query: 373 QPSGQSEYLQQHVAGLQPPSPAQPS 397 +PSG + ++GL+ P QPS Sbjct: 1057 KPSGLQ--YESKLSGLKKPPTLQPS 1079 Score = 38.1 bits (87), Expect = 0.032 Identities = 64/264 (24%), Positives = 89/264 (33%), Gaps = 34/264 (12%) Query: 243 DSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPP---FPGAA 299 ++ L+ V + + QP P P + V +P P PPP P PP G Sbjct: 1315 EAGLSKVVHNTALDPVHQPPPP-PATLKVAEPPPRPPP----------PPPPTGQMNGTV 1363 Query: 300 TGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAY 359 P P AA +P G P LP L + PG G PA + Sbjct: 1364 DHPPP---AAPERKPLGTAPHCPRLP-----LRKTYRENVGGPGAPEGTPAGRARGGSPA 1415 Query: 360 PQP---QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTG 416 P P L+ + + E Q+ + G PP PA ++ G A LP Sbjct: 1416 PLPAKVDEATSGLIRELAAVEDELYQRMLKG-PPPEPAASAAQGTGDPDWEAPGLPPAKR 1474 Query: 417 QNASS--VGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAG 474 + + S V + S + + A + Q G PA A Sbjct: 1475 RKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPA------PSYPHAAS 1528 Query: 475 AGQPQSVPPPQMGGSGPLSAVPGG 498 AG P S PP + P S+ GG Sbjct: 1529 AGTPASPPPLHRPEAYPPSSHNGG 1552 Score = 33.5 bits (75), Expect = 0.78 Identities = 51/231 (22%), Positives = 74/231 (32%), Gaps = 28/231 (12%) Query: 325 PPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQ-- 382 PP + +A+P PP P P Q +P P P L P L+ Sbjct: 1336 PPATLKVAEPPPRPPPPP-----PPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKT 1390 Query: 383 --QHVAGLQPPSPAQPSSTGAA-ASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMA- 438 ++V G P P T A A + A LP + S + +L + + M Sbjct: 1391 YRENVGG-----PGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLK 1445 Query: 439 -----PRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLS 493 P AQG + G+PPA P + A P S Sbjct: 1446 GPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDS--PQDDTLTEHLQS 1503 Query: 494 AVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544 A+ + + P PAPS P ++ P ++ SSH Sbjct: 1504 AIDS-----ILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSH 1549 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 78.6 bits (192), Expect = 2e-14 Identities = 92/404 (22%), Positives = 135/404 (33%), Gaps = 51/404 (12%) Query: 247 TAVSQLPPSEKMSQPTPAQPQSFSVGQPQPP------PPPV---GGAVAQSSAPLP---P 294 T+ + LPP+ S PT P PP PPP ++ ++ P P P Sbjct: 1411 TSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTP 1470 Query: 295 FPGAATGPQPMMAAAQPSQPQGAGPGGQT-LPPTNVTLAQPAMS--LPPQPGPAVGAPAA 351 P T P + P+ P T PPT + PA + LPP P+ Sbjct: 1471 SPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTT 1530 Query: 352 QQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPS--PAQPSSTGAAASPATAA 409 P P P P+ P + L PP+ P+ P +T P T Sbjct: 1531 TTPPPTTTPSPPTTT----PITPPTSTTTL--------PPTTTPSPPPTTTTTPPPTTTP 1578 Query: 410 TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPC 469 + P T + ++ ++ PS T P +P T + P T + P Sbjct: 1579 SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1638 Query: 470 LGPAGAGQPQSVPPPQMGGSGPLSAVPGGP-HAVVPGVPNVPAAVPAPSVPSVSTTSVTM 528 P+ + PPP S P + P P P + P + PS TT++T Sbjct: 1639 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTT 1698 Query: 529 PNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLV 588 P+ P S ++ TP S ++ P T +PT+ P + T Sbjct: 1699 PS-PTTTPSSPITTTTTPSSTTTP-----SPPPTTMTTPSPTTTPSPPTTTMTTLPPTTT 1752 Query: 589 GQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTP 632 S PL PL P + PP + TP Sbjct: 1753 ---------SSPLTTTPL------PPSITPPTFSPFSTTTPTTP 1781 Score = 56.2 bits (134), Expect = 1e-07 Identities = 71/311 (22%), Positives = 96/311 (30%), Gaps = 37/311 (11%) Query: 238 PESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPP-----PPVGGAVA--QSSA 290 P + T S T PP+ + P P + PPP PP + S+ Sbjct: 1495 PPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1554 Query: 291 PLPPF------PGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGP 344 LPP P T P P PS P P PPT T P + P P Sbjct: 1555 TLPPTTTPSPPPTTTTTPPP---TTTPSPPTTTTPS----PPTITTTTPPPTTTPSPPTT 1607 Query: 345 AVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAAS 404 P P PP + P+ P + P +T + Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1667 Query: 405 PATAATLPVGTGQNASSV---GAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPAT 461 P T T P T +S + + + PS P + P T PP T Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP-SSPITTTTTPSSTTTPSPPPT 1726 Query: 462 VGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSV 521 P P+ + PP S PL+ P +P ++ P+ Sbjct: 1727 TMTTPSPTTTPSPPTTTMTTLPPTT-TSSPLTTTP------------LPPSITPPTFSPF 1773 Query: 522 STTSVTMPNVP 532 STT+ T P VP Sbjct: 1774 STTTPTTPCVP 1784 Score = 48.5 bits (114), Expect = 2e-05 Identities = 77/400 (19%), Positives = 116/400 (29%), Gaps = 31/400 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 4032 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 4089 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 4090 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 4148 Query: 370 LPVQPSGQSEYLQQHV---AGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQL 426 P + G Q P+ ++T T G + S+ Sbjct: 4149 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAE 4208 Query: 427 MGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQM 486 + S+ P E+ P+T + + T+ + P + P + P Sbjct: 4209 LTTSNPPPESSTPQTSRSTSSPLTES-------TTLLSTLPPAIEMTSTAPPSTPTAPTT 4261 Query: 487 GGSGPLSAVPGGPHAVVPGVPNV-----PAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQL 541 G + P PG P ++ P PS +TTS P P PL+ + Sbjct: 4262 TSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT-PTPLSTPSII 4320 Query: 542 SSHTPVSRSSSII---------QHVGLPLAPGTHSAPTSLPQSDLS---QFQTQTQPLVG 589 + SS++ G + GT+ LS +F + P Sbjct: 4321 RTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTP 4380 Query: 590 QVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQ 629 T KS P P P S ++ P KPP P Q Sbjct: 4381 SPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQ 4420 Score = 48.1 bits (113), Expect = 3e-05 Identities = 69/352 (19%), Positives = 116/352 (32%), Gaps = 34/352 (9%) Query: 238 PESGTDSSLTAVSQLPPSEKMSQP---TPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPP 294 P + T S T PP+ + P TP+ P + + PPP + ++ P PP Sbjct: 1613 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT----TPPPTTTPSPPTTTTPSPP 1668 Query: 295 FPGAATGP------QPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQ-PAMSLPPQPGPAVG 347 T P P+ P P T P + +T P+ + P P P Sbjct: 1669 ITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTT- 1727 Query: 348 APAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPAT 407 P P P P + + P+ S L PPS P+ + + + T Sbjct: 1728 ---MTTPSPTTTPSP--PTTTMTTLPPTTTSSPLTTTPL---PPSITPPTFSPFSTTTPT 1779 Query: 408 AATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQ 467 +P+ G +E + GP ++ C+ T P +G + Q Sbjct: 1780 TPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANIS-CRATMYPDVPIGQLGQ 1838 Query: 468 PCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGP------HAVVPGVPNVPAAVPAPSVPSV 521 + G + GG P++ V P+ P+ Sbjct: 1839 TVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTT 1898 Query: 522 STTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 + + T P P Q + TP++ ++++ P GT + PT+ P Sbjct: 1899 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 1946 Score = 47.8 bits (112), Expect = 4e-05 Identities = 46/204 (22%), Positives = 67/204 (32%), Gaps = 15/204 (7%) Query: 433 PSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPL 492 PS + P P T PP T P P+ + PPP S P+ Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458 Query: 493 SAVPGGPHAVVPGVPNVPAAVP--APSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRS 550 S P P P + P PS P+ +TT+ P+P + TP++ Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP-------PTTTPITPP 1511 Query: 551 SSIIQHVGLP--LAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSL 608 +S LP P + T+ P + T P+ T P PP + Sbjct: 1512 AST---TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568 Query: 609 IAENKPVVKP-PVADSLANPLQLT 631 P P P + +P +T Sbjct: 1569 TTTPPPTTTPSPPTTTTPSPPTIT 1592 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 1962 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2019 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2020 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2078 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2079 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2135 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2136 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2195 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2196 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2255 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 2256 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2291 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2031 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2088 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2089 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2147 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2148 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2204 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2205 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2264 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2324 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 2325 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2360 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2100 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2157 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2158 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2216 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2217 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2273 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2274 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2333 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2334 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2393 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 2394 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2429 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2169 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2226 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2227 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2285 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2286 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2342 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2343 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2402 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2462 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 2463 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2498 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2238 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2295 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2296 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2354 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2355 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2411 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2412 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2471 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2472 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2531 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 2532 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2567 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2307 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2364 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2365 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2423 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2424 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2480 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2481 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2540 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2541 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2600 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 2601 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2636 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2376 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2433 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2434 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2492 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2493 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2549 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2550 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2609 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2610 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2669 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 2670 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2705 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2445 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2502 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2503 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2561 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2562 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2618 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2619 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2678 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2679 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2738 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 2739 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2774 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2514 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2571 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2572 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2630 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2631 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2687 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2688 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2747 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2748 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2807 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 2808 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2843 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2583 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2640 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2641 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2699 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2700 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2816 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2876 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 2877 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2912 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2652 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2709 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2710 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2768 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2769 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2825 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2826 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2885 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2886 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2945 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 2946 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2981 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2721 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2778 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2779 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2837 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2838 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2894 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2895 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2954 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3014 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3015 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3050 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2790 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2847 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2848 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2906 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2907 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2963 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 2964 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3023 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3024 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3083 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3084 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3119 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2859 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2916 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2917 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2975 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 2976 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3032 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3033 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3092 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3093 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3152 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3153 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3188 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2928 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2985 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 2986 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3044 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3045 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3101 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3102 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3161 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3162 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3221 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3222 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3257 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 2997 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3054 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3055 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3113 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3114 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3170 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3171 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3230 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3290 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3291 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3326 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 3066 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3123 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3124 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3182 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3183 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3239 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3240 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3299 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3300 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3359 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3360 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3395 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 3135 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3192 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3193 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3251 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3252 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3308 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3309 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3368 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3369 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3428 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3429 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3464 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 3204 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3261 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3262 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3320 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3321 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3377 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3378 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3437 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3438 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3497 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3498 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3533 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 3273 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3330 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3331 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3389 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3390 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3446 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3447 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3506 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3507 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3566 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3567 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3602 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 3342 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3399 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3400 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3458 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3459 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3515 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3516 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3575 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3576 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3635 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3636 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3671 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 3411 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3468 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3469 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3527 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3528 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3584 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3585 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3644 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3645 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3704 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3705 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3740 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 3480 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3537 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3596 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3597 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3653 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3654 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3713 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3714 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3773 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3774 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3809 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 3549 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3606 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3607 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3665 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3666 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3722 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3723 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3782 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3783 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3842 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3843 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3878 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 3618 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3675 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3676 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3734 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3735 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3791 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3792 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3851 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3852 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3911 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3912 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3947 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 3687 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3744 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3745 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3803 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3804 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3860 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3861 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3920 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3980 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 3981 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 4016 Score = 41.6 bits (96), Expect = 0.003 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 3756 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3813 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P P G Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3872 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425 P + V P+ Q +T + T P TG + Sbjct: 3873 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3929 Query: 426 LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478 + + P+ P T P V P PTG P T V P P G P Sbjct: 3930 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3989 Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533 + P P G + P P+ P+ + + T P Sbjct: 3990 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4049 Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 P Q + TP++ ++++ P GT + PT+ P Sbjct: 4050 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 4085 Score = 40.0 bits (92), Expect = 0.008 Identities = 61/329 (18%), Positives = 91/329 (27%), Gaps = 27/329 (8%) Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309 +Q P + ++ T P G P P+ + P P G T + Sbjct: 1916 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 1973 Query: 310 QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369 P G QT T +T P G P P Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------ 2027 Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGA 429 P+G + +P P+ TG T T + G Q Sbjct: 2028 ----PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2082 Query: 430 SSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGS 489 + + T G Q PT P T V P P G P + P Sbjct: 2083 TPITTTTTVTPTPTPTGTQT----PT-TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2137 Query: 490 GPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPAPLAQSQQLSSH 544 P G + P P+ P+ + + T P P Q + Sbjct: 2138 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2197 Query: 545 TPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 TP++ ++++ P GT + PT+ P Sbjct: 2198 TPITTTTTV---TPTPTPTGTQT-PTTTP 2222 Score = 33.9 bits (76), Expect = 0.60 Identities = 96/500 (19%), Positives = 146/500 (29%), Gaps = 60/500 (12%) Query: 126 TSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEY 185 T+ P P P ++ P T PS P TT + + P T Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1652 Query: 186 YERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSS 245 T I ++T T S + T + + P S ++ Sbjct: 1653 PTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712 Query: 246 LTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPP------PPVGGAVAQSSAPLPPF---- 295 T S PS + T P + P PP PP + ++ PLPP Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTT----TPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPP 1768 Query: 296 ---PGAATGPQPMMAAA-------QPSQPQGAGPGGQTL-------PPTNVTLAQPAMSL 338 P + T P +P PGG T P ++ A Sbjct: 1769 TFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMY 1828 Query: 339 PPQPGPAVGAPAAQQPQQ-FAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPS----- 392 P P +G PG ++P+ E Q + P+ Sbjct: 1829 PDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTT 1888 Query: 393 ----PAQPSSTGAAASPATAAT-LPVGTGQNASS--VGAQLMGASSQPSEAMAPRTGP-A 444 P P++T + T P GT ++ + + P+ P T P Sbjct: 1889 TTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1948 Query: 445 QGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGG 498 V P PTG P T V P P G P + P P G Sbjct: 1949 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2008 Query: 499 PHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSI 553 + P P+ P+ + + T P P Q + TP++ ++++ Sbjct: 2009 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2068 Query: 554 IQHVGLPLAPGTHSAPTSLP 573 P GT + PT+ P Sbjct: 2069 ---TPTPTPTGTQT-PTTTP 2084 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 78.6 bits (192), Expect = 2e-14 Identities = 81/266 (30%), Positives = 89/266 (33%), Gaps = 43/266 (16%) Query: 253 PPSEKMSQPTPAQPQSFSV----GQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPM--- 305 PP K P P +S S G+PQ PPP G Q P PP PG GP P Sbjct: 72 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN---QPQGPPPP-PGKPQGPPPQGGN 127 Query: 306 --MAAAQPSQPQGAGPGGQTL-----PPTNVTLAQPAMSLPPQ-PGPAVGAPAAQQPQQF 357 P +PQG P G PP P PQ P P G P PQ Sbjct: 128 RPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 187 Query: 358 AYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQ--------------PPSPAQPSSTGAAA 403 PQ PPG P G Q G PP P +P Sbjct: 188 KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 247 Query: 404 SPATAATLPVGTGQNASSVG-AQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATV 462 P G Q + G ++ A S P + P P Q G P G PP Sbjct: 248 GNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGP---PQQEGN----NPQGPPPPAG 300 Query: 463 GGVVQPCLGPAGAGQPQSVPPPQMGG 488 G QP P AGQPQ P P GG Sbjct: 301 GNPQQPQAPP--AGQPQGPPRPPQGG 324 Score = 78.2 bits (191), Expect = 3e-14 Identities = 83/291 (28%), Positives = 95/291 (32%), Gaps = 47/291 (16%) Query: 254 PSEKMSQPTPAQPQSFSVGQPQPP-------PPPVGGAVAQSSAPLPPFPGAATGPQPM- 305 PS P PQ + Q PP PPP GG Q PP PG GP P Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQG----PPPPGKPQGPPPQG 84 Query: 306 ----MAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPG------PAVGAPAAQQPQ 355 + P +PQG P G P PPQ G P G P PQ Sbjct: 85 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQ 144 Query: 356 QFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGT 415 P+ PPG P G ++ PP P +P P G Sbjct: 145 GDKSRSPRSPPGKPQGPPPQGGNQ------PQGPPPPPGKPQGPPPQGGKKPQGPPPPGK 198 Query: 416 GQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGA 475 Q G + + S P + P P QGG QP G PP P P G Sbjct: 199 PQGPPPQGDKSRSSQSPPGKPQGP---PPQGGN----QPQGPPPPPGKPQGPP---PQGG 248 Query: 476 GQPQSVP-------PPQMGGSGPLSA--VPGGPHAVVPGVPNVPAAVPAPS 517 +PQ P PP GGS SA PG P N P P P+ Sbjct: 249 NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA 299 Score = 67.4 bits (163), Expect = 5e-11 Identities = 79/260 (30%), Positives = 94/260 (36%), Gaps = 37/260 (14%) Query: 268 SFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPT 327 S G PQ P P G + P PP PG GP P ++PQG P G+ P Sbjct: 30 SLIAGNPQGPSPQGGN---KPQGPPPP-PGKPQGPPPQGG----NKPQGPPPPGKPQGPP 81 Query: 328 NVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAG 387 Q S P+ P G P PQ PQ PP P +P G G Sbjct: 82 ----PQGDKSRSPRSPP--GKPQGPPPQGGNQPQGPPPP----PGKPQGPPPQGGNRPQG 131 Query: 388 LQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGA-QLMGASSQPSEAMAPRTGPAQG 446 PP P +P + + P G Q G Q G P + P P QG Sbjct: 132 --PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP---PPQG 186 Query: 447 GQ-----VAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLS--AVPGGP 499 G+ P +P G PP G + P G+PQ PPPQ GG+ P PG P Sbjct: 187 GKKPQGPPPPGKPQGPPPQ--GDKSRSSQSP--PGKPQG-PPPQ-GGNQPQGPPPPPGKP 240 Query: 500 HAVVPGVPNVPAAVPAPSVP 519 P N P P P P Sbjct: 241 QGPPPQGGNKPQGPPPPGKP 260 Score = 64.3 bits (155), Expect = 4e-10 Identities = 82/311 (26%), Positives = 98/311 (31%), Gaps = 31/311 (9%) Query: 304 PMMAAAQPSQPQGAG---PGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYP 360 P + A P P G P G PP P PQ P G P PQ Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88 Query: 361 QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNAS 420 P+ PPG P G ++ PP P +P P G Q Sbjct: 89 SPRSPPGKPQGPPPQGGNQ------PQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP 142 Query: 421 SVGAQLMGASSQPSEAMAPRTGPAQGGQ--VAPCQPTGVP--PATVGGVVQPCLGPAGAG 476 G + S P + P P QGG P P G P P GG + GP G Sbjct: 143 PQGDKSRSPRSPPGKPQGP---PPQGGNQPQGPPPPPGKPQGPPPQGG--KKPQGPPPPG 197 Query: 477 QPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAP--SVPSVSTTSVTMPNVPAP 534 +PQ PPPQ S + PG P P N P P P P P P Sbjct: 198 KPQG-PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 256 Query: 535 LAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDT 594 + Q P ++ S Q P PG P PQ + + Q P G Sbjct: 257 PGKPQ-----GPPAQGGSKSQSARSP--PGKPQGP---PQQEGNNPQGPPPPAGGNPQQP 306 Query: 595 RRKSEPLPQPP 605 + PQ P Sbjct: 307 QAPPAGQPQGP 317 Score = 52.8 bits (125), Expect = 1e-06 Identities = 57/193 (29%), Positives = 71/193 (36%), Gaps = 32/193 (16%) Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFP 296 G +S + S Q PP + +QP P G+PQ PPP GG Q PP P Sbjct: 145 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQ-GGKKPQG----PPPP 196 Query: 297 GAATGPQPM-----MAAAQPSQPQGAGPGGQTLP-----PTNVTLAQPAMSL-----PPQ 341 G GP P + + P +PQG P G P P P PP Sbjct: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 256 Query: 342 PGPAVGAPA--AQQPQQFAYP--QPQIPPGH-----LLPVQPSGQSEYLQQHVAGLQPPS 392 PG G PA + Q P +PQ PP P P+G + Q QP Sbjct: 257 PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 316 Query: 393 PAQPSSTGAAASP 405 P +P G + P Sbjct: 317 PPRPPQGGRPSRP 329 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 78.2 bits (191), Expect = 3e-14 Identities = 108/415 (26%), Positives = 155/415 (37%), Gaps = 55/415 (13%) Query: 244 SSLTAVSQLPPSEKMSQPTP-----AQPQSFSVGQPQPPPPPVGGAV---AQSSAPLP-- 293 S L S LP P P A P S +V P P+ A +SAPL Sbjct: 1399 SPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIP 1458 Query: 294 ---PFPGAATGPQPMMAAAQPSQPQ-GAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAP 349 P +A+GP + + P P A PG +L P+ + + A++L P++ + Sbjct: 1459 ISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSS 1518 Query: 350 AAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAA 409 PGH L + P+ HV GL S P+ + PA+A Sbjct: 1519 QT--------------PGHPLLLAPTSS------HVPGLN--STVAPACSPVLV-PASAL 1555 Query: 410 TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPC 469 P + N + A L+ +S S+A+A P Q A P+ PP V+ P Sbjct: 1556 ASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPS 1615 Query: 470 LGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMP 529 G A P P M S+ PG A VP P V APS ST ++ Sbjct: 1616 PGAAPVLASSQTPVPVMAP----SSTPGTSLASASPVP-APTPVLAPS----STQTMLPA 1666 Query: 530 NVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVG 589 VP+PL +S ++ + ++ +G T S T PQ P Sbjct: 1667 PVPSPLPSP---ASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASS 1723 Query: 590 QVDDTRRKSEPLPQPPL----SLIAENKPVVKP--PVADSLANPLQLTPMNSLAT 638 V + P PPL +L P + P PV + A+ L L P +S A+ Sbjct: 1724 LVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSAS 1778 Score = 65.9 bits (159), Expect = 1e-10 Identities = 120/497 (24%), Positives = 177/497 (35%), Gaps = 106/497 (21%) Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQ-----PPPPPVGGAVAQ---- 287 GPE + V Q+ P+ M +PA P +P PP P G++ Q Sbjct: 1029 GPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPS 1088 Query: 288 -----SSAPLPPFPGAATGP-QPMMAAAQPSQPQGAG--------PGGQTLPP-----TN 328 S PP P + P P P+ P G+ P G T PP T+ Sbjct: 1089 PLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTS 1148 Query: 329 VTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYP---QPQIPPGHLLPVQPSGQSEYLQQHV 385 T A + P P PA PQ+ Q ++P G ++ + GQ L Q Sbjct: 1149 TTTATATTTAVPAPTPA--------PQRLILSPDMQARLPSGEVVSI---GQLASLAQRP 1197 Query: 386 ---AGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGAS------SQPS-- 434 AG P Q + A L VG + L+ A SQP+ Sbjct: 1198 VANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHV 1257 Query: 435 ---EAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSG- 490 +A+AP GP V P PA G + P A Q VPP + +G Sbjct: 1258 ALIQAVAPTPGPTP-VSVLPSSTPSTTPAPTGLSL-----PLAANQ---VPPTMVNNTGV 1308 Query: 491 -----------------PLSAVPGGPHAVVPGVPN-----VPAAVPAPSVPS----VSTT 524 PL+ P P + +P V N P +P P++ + + T Sbjct: 1309 VKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTP 1368 Query: 525 SVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLA-PGTHSAPTSLPQSDLSQFQTQ 583 ++ P + + S ++S+ P + +I + +P + PG S+P +P S Sbjct: 1369 TLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNS-------- 1420 Query: 584 TQPLVGQVDDTRRKSEPLPQP-PLSLIAENKPVVKPPVADSLANPLQLTPMN-SLATSVF 641 PL V T S PL P+S+ P+ ++ PL ++ +L TSV Sbjct: 1421 -SPLASPVSST--VSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVT 1477 Query: 642 SIAIPVDGDEDRNPSTA 658 PV PS A Sbjct: 1478 PPLAPVVPAAPGPPSLA 1494 Score = 62.8 bits (151), Expect = 1e-09 Identities = 123/500 (24%), Positives = 185/500 (37%), Gaps = 105/500 (21%) Query: 76 GDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPG 135 G A +P + + L +++ + P + +S + A AS SAP + Sbjct: 1409 GPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSAS 1468 Query: 136 GPQLAGSSAGP----VTAAPSQP---PTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYER 188 GP L S P V AAP P P+ S + L + Sbjct: 1469 GPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAP--------------- 1513 Query: 189 DSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGG---SVVVVVASMQGAHGPESGTDSS 245 S SS T H T+ GL +T S V+V AS + P + + Sbjct: 1514 -SLSSSQTPG-----HPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAP 1567 Query: 246 LTAVSQLPPSEKMSQP--TPAQPQSF---SVGQPQPPPPPVGGAVAQSSAPLP---PFPG 297 A S L P+ SQ TP P + ++ P P PP APLP P PG Sbjct: 1568 AQA-SLLAPASSASQALATPLAPMAAPQTAILAPSPAPP---------LAPLPVLAPSPG 1617 Query: 298 AATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQF 357 AA P++A++Q P A + P T++ A P P P P + + Q Sbjct: 1618 AA----PVLASSQTPVPVMAP---SSTPGTSLASASPV----PAPTPVLAPSSTQTMLPA 1666 Query: 358 AYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQ 417 P P LP S Q+ L +PA + G + + + TL +GTG Sbjct: 1667 PVPSP-------LPSPASTQTLAL----------APALAPTLGGS---SPSQTLSLGTGN 1706 Query: 418 NASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQ 477 Q + S P+ ++ P PAQ +AP P G P T+ P L PA Sbjct: 1707 PQGPFPTQTL--SLTPASSLVPT--PAQTLSLAPGPPLG-PTQTLSLAPAPPLAPA---- 1757 Query: 478 PQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQ 537 P+ P + P + PA SV +++ + +P + AQ Sbjct: 1758 ------------SPVGPAPAHTLTLAPASSSASLLAPA-SVQTLTLSPAPVPTLGPAAAQ 1804 Query: 538 SQQL---SSHTPVSRSSSII 554 + L S+ +P S++SS++ Sbjct: 1805 TLALAPASTQSPASQASSLV 1824 Score = 53.9 bits (128), Expect = 6e-07 Identities = 107/389 (27%), Positives = 135/389 (34%), Gaps = 69/389 (17%) Query: 52 SRATDYGPEEVCERSSSEETLNN-VGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSA 110 S T P + SS LN+ V A +P V + L +A APA + A Sbjct: 1517 SSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPA 1576 Query: 111 RSVSGALASTLAAAATS-------------------APAPGAPGGPQLAGSSAGPVTAAP 151 S S ALA+ LA A AP+PGA P LA S AP Sbjct: 1577 SSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGA--APVLASSQTPVPVMAP 1634 Query: 152 SQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQT 211 S P T + + P S ++L S QT Sbjct: 1635 SSTPGTSLASASPVPAPTPVLAP--------------SSTQTMLPAPVPSPLPSPASTQT 1680 Query: 212 AERDSGLGAT-GGSVVVVVASM--QGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQS 268 L T GGS S+ GP SLT S L PTPAQ S Sbjct: 1681 LALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSL-------VPTPAQTLS 1733 Query: 269 FSVGQPQPPPPPVGGAVAQSSAPLPPF-PGAATGPQPMMAAAQPSQPQGAGPGGQTLPPT 327 + P PP+G S AP PP P + GP P A A L P Sbjct: 1734 LA------PGPPLGPTQTLSLAPAPPLAPASPVGPAP----AHTLTLAPASSSASLLAPA 1783 Query: 328 NVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL--LPVQPSGQSEYLQQHV 385 +V ++L P P P +G PAA Q A Q P L V SG + V Sbjct: 1784 SV----QTLTLSPAPVPTLG-PAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMV 1838 Query: 386 AGLQPPSPAQPSS----TGAAASPATAAT 410 + L P S +P + +G + P+TA + Sbjct: 1839 SRL-PVSKDEPDTLTLRSGPPSPPSTATS 1866 Score = 41.6 bits (96), Expect = 0.003 Identities = 85/368 (23%), Positives = 128/368 (34%), Gaps = 71/368 (19%) Query: 250 SQLPP-SEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPL----PPFPGAAT---- 300 SQ+PP S P PA P PPP + S+PL P P +A+ Sbjct: 2489 SQIPPCSSPACTPPPA-----CTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNL 2543 Query: 301 --GPQP-----MMAAAQPSQPQGAGPGGQT------LPPTNVT--------LAQPAMSLP 339 G +P A A P + A +PP ++ +++ +SL Sbjct: 2544 PLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLT 2603 Query: 340 PQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYL-QQHVAGLQ-PPSPA--- 394 P P++ A P P G L V P G+ L GL+ PPS A Sbjct: 2604 PS-APSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDE 2662 Query: 395 ---QPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAP 451 +P + T A P + + + + A S S A + GP+ P Sbjct: 2663 PLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPS------P 2716 Query: 452 CQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVP--------------- 496 +P P V+ + G G+P P P++ P V Sbjct: 2717 ARP---PRRRTSADVE--IRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQR 2771 Query: 497 GGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQH 556 G +VPGV A+ +PSV S+S + P + P + S TP + +H Sbjct: 2772 GAASTLVPGVSETSASPGSPSVRSMSGPE-SSPPIGGPCEAAPSSSLPTPPQQPFIARRH 2830 Query: 557 VGLPLAPG 564 + L + G Sbjct: 2831 IELGVTGG 2838 Score = 38.1 bits (87), Expect = 0.032 Identities = 77/364 (21%), Positives = 131/364 (35%), Gaps = 47/364 (12%) Query: 416 GQNASSVGAQ---LMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGP 472 G A + GA ++ A S PR PA+ P PA+ + P L P Sbjct: 2401 GARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAI-PALVP 2459 Query: 473 AGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVP 532 P S P P + P++ +P V +P+ P +P S+ + T P Sbjct: 2460 V----PVSAPVP-ISAPNPITILP---------VHILPSPPPPSQIPPCSSPACTPPPAC 2505 Query: 533 APLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVD 592 P +HTP + ++ PL G S P S ++L +G Sbjct: 2506 TPPP------AHTPPPAQTCLVTPSS-PLLLGPPSVPISASVTNLP---------LGLRP 2549 Query: 593 DTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDED 652 + ++ L P +A VA S + L L P L I + + Sbjct: 2550 EAELCAQALASPESLELAS--------VASSETSSLSLVPPKDLLPVAVEILPVSEKNLS 2601 Query: 653 RNPS--TAFYQAFHLNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVE 710 PS + +A + +E ++ DSA G + + E + + +S+ + Sbjct: 2602 LTPSAPSLTLEAGSIPNGQEQEAP-DSAEGTTLTVLPEGEELPLCVSESNGLELPPSAAS 2660 Query: 711 VLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQ 770 E ++E +E + E SS ++ +L T + STS + P P + Sbjct: 2661 --DEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPAR 2718 Query: 771 PPQQ 774 PP++ Sbjct: 2719 PPRR 2722 Score = 36.2 bits (82), Expect = 0.12 Identities = 115/548 (20%), Positives = 184/548 (33%), Gaps = 88/548 (16%) Query: 19 TAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATD-YGPEEVC---ERSSSEETLNN 74 T++ T T S + P E T +V++ S + GP R+S++ + Sbjct: 2673 TSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRG 2732 Query: 75 VGDAETPGTVSPNLL--LDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPG 132 G P +L L G+L V R GA ++ + + ++ +PG Sbjct: 2733 QGTGRPGQPPGPKVLRKLPGRLVTVVEEKEL---VRRRRQQRGAASTLVPGVSETSASPG 2789 Query: 133 APG-----GPQLAGSSAGPVTAAPSQ----PPTTCSSRFRVIKLD-HGSGEPYRRGRWTC 182 +P GP+ + GP AAPS PP R I+L G G P Sbjct: 2790 SPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSP-------- 2841 Query: 183 MEYYERDSDSSVLTRSGDCIRHSSTFDQTAER---DSGLGATGGSVVVVVASMQGAHGPE 239 + D ++L + ++ R D+G G V A G Sbjct: 2842 -----ENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRG-------VDEAPSSTLKGKT 2889 Query: 240 SGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAA 299 +G D P P P++ V P P + G P P P Sbjct: 2890 NGAD-----------------PVPG-PETLIVADPVLEPQLIPG-------PQPLGPQPV 2924 Query: 300 TGPQPMMAAAQPSQPQGAGPGGQTLP-PTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFA 358 P P+++ + + +G P + LP P ++ A S P +P P Sbjct: 2925 HRPNPLLSPVE-KRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLV 2983 Query: 359 YPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQN 418 P + + V S ++ PPSP +PS +T+ G G+ Sbjct: 2984 CPTATV-ANTVTTVTISTSPPKRKRGRPPKNPPSP-RPSQLPVLDRDSTSVLESCGLGRR 3041 Query: 419 ASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGG-----VVQPCLGPA 473 G SS + P T A+ + G+ GG V+Q L A Sbjct: 3042 RQPQGQGESEGSSSDEDGSRPLTRLAR----LRLEAEGMRGRKSGGSMVVAVIQDDLDLA 3097 Query: 474 GAGQ-PQSVPPPQMGGSGPLSAVPGGPHAVVP-----GVPNVPAAVPAPSVPSVSTTSVT 527 +G + PP + + L + P ++VP +P A P P ++ Sbjct: 3098 DSGPGGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPVGGSPGLAKRGRL 3157 Query: 528 MPNVPAPL 535 P P+PL Sbjct: 3158 QP--PSPL 3163 Score = 35.4 bits (80), Expect = 0.20 Identities = 78/347 (22%), Positives = 119/347 (34%), Gaps = 37/347 (10%) Query: 232 MQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAP 291 ++GA G + T V + + P P V +P P P P + + Sbjct: 2399 LRGARAETQGANH--TPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPA 2456 Query: 292 LPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMS-LPPQPGPAVGAPA 350 L P P +A P P+ A P T+ P ++ + P S +PP PA P Sbjct: 2457 LVPVPVSA--PVPISA-----------PNPITILPVHILPSPPPPSQIPPCSSPACTPPP 2503 Query: 351 AQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPS-PAQPSSTGAAASPATAA 409 A P P PP V PS S L L PPS P S T A Sbjct: 2504 ACTPP----PAHTPPPAQTCLVTPS--SPLL------LGPPSVPISASVTNLPLGLRPEA 2551 Query: 410 TLPVGTGQNASSVGAQLMGASSQPSEAMA-PRTGPAQGGQVAPCQPTGVPPATVGGVVQP 468 L + S+ + +S S ++ P+ ++ P + + Sbjct: 2552 ELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTL 2611 Query: 469 CLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTM 528 G GQ Q P G + L+ +P G +P + + P PS ++ Sbjct: 2612 EAGSIPNGQEQEAPDSAEGTT--LTVLPEGEE--LPLCVSESNGLELP--PSAASDEPLQ 2665 Query: 529 PNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPL-APGTHSAPTSLPQ 574 + A + + TP S + V + AP T S+ TS P+ Sbjct: 2666 EPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPE 2712 Score = 34.3 bits (77), Expect = 0.46 Identities = 81/355 (22%), Positives = 117/355 (32%), Gaps = 62/355 (17%) Query: 282 GGAVAQSS-APLPPFPGAATGPQPMMAAAQPSQPQGAG-----PGGQTLPPTNVTLAQPA 335 GG +S A P PG + A A+ QGA QT T PA Sbjct: 2376 GGTHRRSKKAKAPERPGTRVSERLRGARAET---QGANHTPVISAHQTRSTTTPPRCSPA 2432 Query: 336 MSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ 395 P+P P A P P +P +P+ L H+ PP Sbjct: 2433 RERVPRPAPRPRPTPASAPAAIPALVP-VPVSAPVPISAPNPITILPVHILPSPPPPSQI 2491 Query: 396 PSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPT 455 P + A +P A T P A P PAQ V P P Sbjct: 2492 PPCSSPACTPPPACT----------------------PPPAHTP--PPAQTCLVTPSSPL 2527 Query: 456 GVPPATV---GGVVQPCLG--PAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVP 510 + P +V V LG P Q++ P+ +++ ++VP +P Sbjct: 2528 LLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLP 2587 Query: 511 AAVP-----------APSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGL 559 AV PS PS++ + ++PN Q Q+ + + + + L Sbjct: 2588 VAVEILPVSEKNLSLTPSAPSLTLEAGSIPN-----GQEQEAPDSAEGTTLTVLPEGEEL 2642 Query: 560 PLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKP 614 PL + S LP S S Q +PL + R SE L + + KP Sbjct: 2643 PLCV-SESNGLELPPSAASDEPLQ-EPL-----EADRTSEELTEAKTPTSSPEKP 2690 Score = 30.0 bits (66), Expect = 8.6 Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 37/140 (26%) Query: 458 PPATVGGV-VQPCLGPAGAGQPQSVPPPQ-MGGSGPLSAVPGGPHAVVPGVPNVPAAVPA 515 P A +G V V+P GP + QP P PQ + S +SA P GP + P P +P Sbjct: 1015 PRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPP 1074 Query: 516 ------------------------PSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSS 551 P P++S P PAP+ S P SS Sbjct: 1075 LQPNSGSLPQVLPSPLGVLSGTSRPPTPTLS----LKPTPPAPVRLSP-----APPPGSS 1125 Query: 552 SIIQHVGLPLAPGTHSAPTS 571 S+++ + +P PG P + Sbjct: 1126 SLLKPLTVP--PGYTFPPAA 1143 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 77.0 bits (188), Expect = 6e-14 Identities = 104/405 (25%), Positives = 120/405 (29%), Gaps = 73/405 (18%) Query: 254 PSEKMSQPTPAQPQSFSV--GQPQPP-----PPPVGGAVAQSSAPLPPFPGAATGPQPM- 305 PS P A PQ + G P PP PPP GG Q PP PG GP P Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP---PPPPGKPQGPPPQG 85 Query: 306 ----MAAAQPSQPQGAGPGGQ-----TLPPTNVTLAQPAMSLPPQ-PGPAVGAPAAQQPQ 355 P +PQG P G PP P PQ P P G P PQ Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 145 Query: 356 QFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGT 415 PQ PPG P G ++ +P P P P G Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP-----PPGK 200 Query: 416 GQNASSVGAQLMGASSQPSEAMAP---RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGP 472 Q G P + P +Q + P +P G P P Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP-------------P 247 Query: 473 AGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVP 532 G QPQ PPP PG P P N P P P P P Sbjct: 248 QGGNQPQGPPPP-----------PGKPQGPPPQGGNKPQGPPPPG----------KPQGP 286 Query: 533 APLAQSQQLSSHTPVSRSSSI-----IQHVGLPLAPGTHSAPT----SLPQSDLSQFQTQ 583 P S+ SS +P + Q G P PG P + PQ + Q Sbjct: 287 PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 346 Query: 584 TQPLVGQVDDTRRKSEP-LPQPPLSLIAENKPVVKPPVADSLANP 627 P G +S P PQ P N PP + P Sbjct: 347 GPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391 Score = 76.3 bits (186), Expect = 1e-13 Identities = 84/275 (30%), Positives = 92/275 (33%), Gaps = 52/275 (18%) Query: 238 PESGTDSSLTAVSQLPPSEKMSQPTPA--QPQSFSVGQPQPP-----PPPVGGAVAQSSA 290 P G + S + S+ PP + P QPQ G P PP PPP GG Q Sbjct: 163 PPQGDNKSRS--SRSPPGKPQGPPPQGGNQPQ----GPPPPPGKPQGPPPQGGNKPQG-- 214 Query: 291 PLPPFPGAATGPQPM------MAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGP 344 PP PG GP P A + P +PQG P G P PP PG Sbjct: 215 --PPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP----------QGPPPPPGK 262 Query: 345 AVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHV-----------AGLQPPSP 393 G P PQ PQ PPG P G S+ G QP P Sbjct: 263 PQGPP----PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP 318 Query: 394 AQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ 453 P P P G G G S S A +P P Q Sbjct: 319 PPPPGK-PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS-ARSPPGKPQGPPQQEGNN 376 Query: 454 PTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGG 488 P G PP G QP P AGQPQ P P GG Sbjct: 377 PQGPPPPAGGNPQQPQAPP--AGQPQGPPRPPQGG 409 Score = 70.5 bits (171), Expect = 6e-12 Identities = 88/289 (30%), Positives = 103/289 (35%), Gaps = 52/289 (17%) Query: 253 PPSEKMSQPTPAQPQSFSV----GQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAA 308 PP + P +S S G+PQ PPP G Q P PP PG GP P Sbjct: 155 PPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN---QPQGPPPP-PGKPQGPPPQGG- 209 Query: 309 AQPSQPQGAGPGG--QTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPP 366 ++PQG P G Q PP +Q A S P G P PQ PQ PP Sbjct: 210 ---NKPQGPPPPGKPQGPPPQGDNKSQSARSPP-------GKPQGPPPQGGNQPQGPPPP 259 Query: 367 GHLLPVQPSGQSEYLQQHVAGLQPPS-PAQPSSTGAAASPATAATLPVGTGQNASSVGA- 424 P +P G G PP P P G + S ++ + P G Q G Sbjct: 260 ----PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS--PPGKPQGPPPQGGN 313 Query: 425 QLMGASSQPSEAMAPRTGPAQGGQVA-----PCQPTGVPPATVGGVVQPCLGPAGA--GQ 477 Q G P + P P QGG P +P G PP G + P G G Sbjct: 314 QPQGPPPPPGKPQGP---PPQGGNKPQGPPPPGKPQGPPPQG-GSKSRSARSPPGKPQGP 369 Query: 478 PQSV------PPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPS 520 PQ PPP GG+ P P A G P P P PS Sbjct: 370 PQQEGNNPQGPPPPAGGN------PQQPQAPPAGQPQGPPRPPQGGRPS 412 Score = 52.0 bits (123), Expect = 2e-06 Identities = 58/200 (29%), Positives = 70/200 (35%), Gaps = 42/200 (21%) Query: 238 PESGTDSSLTAVSQLPPSEKMSQPTPA--QPQSFSVGQPQPP-----PPPVGGAVAQSSA 290 P G + S +A S PP + P QPQ G P PP PPP GG Q Sbjct: 225 PPQGDNKSQSARS--PPGKPQGPPPQGGNQPQ----GPPPPPGKPQGPPPQGGNKPQG-- 276 Query: 291 PLPPFPGAATGPQPM------MAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPG- 343 PP PG GP P + + P +PQG P G P PPQ G Sbjct: 277 --PPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 334 Query: 344 -----PAVGAPAAQQPQQFAYPQ--------PQIPPGH-----LLPVQPSGQSEYLQQHV 385 P G P PQ + + PQ PP P P+G + Q Sbjct: 335 KPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP 394 Query: 386 AGLQPPSPAQPSSTGAAASP 405 QP P +P G + P Sbjct: 395 PAGQPQGPPRPPQGGRPSRP 414 >gi|91208418 transcription elongation regulator 1 isoform 2 [Homo sapiens] Length = 1077 Score = 76.6 bits (187), Expect = 8e-14 Identities = 116/491 (23%), Positives = 172/491 (35%), Gaps = 31/491 (6%) Query: 264 AQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQT 323 AQ Q+ P PPP V P PPF G GP P P P G P Sbjct: 22 AQQQALRFRGPAPPPNAVMRGPPPLMRPPPPF-GMMRGPPP-----PPRPPFGRPPFDPN 75 Query: 324 LPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP---QIPPGHLLPVQPSGQSEY 380 +PP + P PP P + P P + P P PPG + PV G Sbjct: 76 MPP----MPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPG-MPPVTAPGTPAL 130 Query: 381 LQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQ-PSEAMAP 439 ++ +P A + +A T P G S ++ A +Q ++A A Sbjct: 131 PPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQ 190 Query: 440 RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSA-VPGG 498 AQ A Q A Q Q Q+ Q + A V Sbjct: 191 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQ 250 Query: 499 PHAVVPGVPNVPAAVPAPSV---PSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQ 555 A G + PAP+V S ST S T + +Q +S+ T ++ S Sbjct: 251 VQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAV 310 Query: 556 HVGLPLAPGTHSAPTSLPQSDLSQFQTQTQP-----LVGQVDDTRRKSEPLPQPPLSLIA 610 V P + APT+ P + Q QT P V Q P+ PP + Sbjct: 311 SVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPL 370 Query: 611 ENKPVVKPPVADSLANPL--QLTPMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTL 668 P+ P V +A P+ + P ++A S ++A E TA + ++ N Sbjct: 371 PGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNN- 429 Query: 669 KESKSLWDSASG-GGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVE---RNS 724 + +S W+ ++ KI++ + + EE + +E IKE+ E Sbjct: 430 RTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEE 489 Query: 725 LLERENALLKS 735 + E E A K+ Sbjct: 490 MTEEEKAAQKA 500 Score = 49.3 bits (116), Expect = 1e-05 Identities = 61/272 (22%), Positives = 94/272 (34%), Gaps = 33/272 (12%) Query: 84 VSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLAGSS 143 ++P L Q+ A A A A A++ + A A A A A A A + Sbjct: 173 LTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 232 Query: 144 AGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIR 203 A A +Q ++ + + G+ P T S Sbjct: 233 AQAQAQAQAQVQAQVQAQVQAQAV--GASTP--------------------TTSSPAPAV 270 Query: 204 HSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTP 263 +ST T + T SV V++ P + + +AVS P+ +S P P Sbjct: 271 STSTSSSTPSSTTSTTTTATSVAQTVST------PTTQDQTPSSAVSVATPTVSVSTPAP 324 Query: 264 AQPQSFSVGQPQPP--PPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGG 321 +V QP P PP V +V Q + +P FP P + P G PG Sbjct: 325 TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPG- 383 Query: 322 QTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQ 353 + P V + P +++ P GA A + Sbjct: 384 --MAPPIVPMIHPQVAIAASPATLAGATAVSE 413 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 75.9 bits (185), Expect = 1e-13 Identities = 123/533 (23%), Positives = 171/533 (32%), Gaps = 78/533 (14%) Query: 71 TLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAAT---- 126 ++++ G + P T P + G +A PAN V AL A+A+ Sbjct: 261 SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL 320 Query: 127 -SAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEY 185 + P PG P G G + P + PT S + + P R Sbjct: 321 GAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR-------- 372 Query: 186 YERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSS 245 +SS+ +A S ++ S AS P S + Sbjct: 373 ----------------FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPT 416 Query: 246 LTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSA---PLPPFPGAATGP 302 +VS PP K +Q P+ P Q PPPPP G +A S+A P PP GA + Sbjct: 417 SLSVSNQPP--KYTQ--PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472 Query: 303 QPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP 362 P ++ Q Q S PP PG A P A+P Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG-AFPHPLEGGSSHHAHPYA 531 Query: 363 QIP-----------PGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSST------------ 399 P P HL P P Q Y Q G S + SS+ Sbjct: 532 MSPSLGSLRPYPPGPAHLPP--PHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS 589 Query: 400 ---GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTG 456 G +P +P T +A+ ASS A GP G+ AP Sbjct: 590 PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP----- 644 Query: 457 VPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAP 516 P P P ++ PP G+ P P GP PG P V P P Sbjct: 645 -SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSP----PAGPGTFKPGSPTVG---PGP 696 Query: 517 SVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAP 569 P+ + ++P PA A LS+ + + P+ P +P Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749 Score = 65.5 bits (158), Expect = 2e-10 Identities = 93/329 (28%), Positives = 118/329 (35%), Gaps = 50/329 (15%) Query: 334 PAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPP-GHLLPVQPSGQSEYLQQHVAGLQPPS 392 P PP P P P +QP+ P P + P G+ P++P + Q G PP Sbjct: 161 PPPLFPPSPQPPDSTP--RQPEASFEPHPSVTPTGYHAPMEPPTSRMF--QAPPGAPPPH 216 Query: 393 PA-QPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQP--------------SEAM 437 P P TG S P G G ASSVG G P + Sbjct: 217 PQLYPGGTGGVLSGPPMG--PKGGGA-ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT 273 Query: 438 APRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQP---QSVPPPQMGGSGPLSA 494 P T P GG + P+ PPA V P L P A +P S PP +G PL Sbjct: 274 KPPTTPVGGGNL----PSAPPPANFPHVT-PNLPPPPALRPLNNASASPPGLGAQ-PLPG 327 Query: 495 VPGGPHAV-------VPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPV 547 PHA+ PG P P+P +++S P + P + S S+ Sbjct: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASS 387 Query: 548 SRSSSIIQHVGLPLAPGTHSAPTSLPQ----SDLSQFQTQTQPLVGQVDDTRRKSEPLPQ 603 S SSS P + S P S P S +Q TQP + P P Sbjct: 388 SSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL--PSQAVWSQGPPPP 445 Query: 604 PPLSLIAENK---PVVKPPV--ADSLANP 627 PP + N P PP A S A+P Sbjct: 446 PPYGRLLANSNAHPGPFPPSTGAQSTAHP 474 Score = 61.6 bits (148), Expect = 3e-09 Identities = 107/416 (25%), Positives = 136/416 (32%), Gaps = 58/416 (13%) Query: 253 PPSEKMSQPTPAQPQSFSVGQPQ--------PPPPPVGGAVAQSSA----------PLPP 294 PP+ +M Q P P P PP P GG A S P P Sbjct: 200 PPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTP 259 Query: 295 FPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQP 354 +++G P+ P G G PP N P + PP P A +A P Sbjct: 260 ISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNA-SASPP 318 Query: 355 QQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ-------PSSTGAAASPAT 407 A P PGHL GQ + GL PP P + P S A+S A Sbjct: 319 GLGAQPL----PGHLPSPHAMGQG------MGGL-PPGPEKGPTLAPSPHSLPPASSSAP 367 Query: 408 AATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQ 467 A + ++SS A +SS S A P Q P P PP T V Sbjct: 368 APPMRFPYSSSSSSSAAASSSSSSSSSSA-----SPFPASQALPSYPHSFPPPTSLSVSN 422 Query: 468 PCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVT 527 P QP S+P + GP P P+ + N A P P PS S Sbjct: 423 Q---PPKYTQP-SLPSQAVWSQGP---PPPPPYGRLLANSN---AHPGPFPPSTGAQSTA 472 Query: 528 MPNVPA--PLAQSQQLSSHTPVSRSSSIIQHVGL--PLAPGTHSAPTSLPQSDLSQFQTQ 583 P V Q QQ + QH G P PG P S + Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAM 532 Query: 584 TQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATS 639 + P +G + LP PP S ++ ++ P S +N T S S Sbjct: 533 S-PSLGSLRPYPPGPAHLP-PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCS 586 Score = 57.8 bits (138), Expect = 4e-08 Identities = 98/380 (25%), Positives = 133/380 (35%), Gaps = 56/380 (14%) Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFS----VGQP--QPPPPPVGGAVAQSSA 290 GP G A S P+ P P P S S G P +PP PVGG S+ Sbjct: 230 GPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAP 289 Query: 291 PLPPFPGAATG--PQPMMAAAQPSQPQGAGPGGQTLP---PTNVTLAQPAMSLPPQPGPA 345 P FP P P + + G G Q LP P+ + Q LP PGP Sbjct: 290 PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--PGPE 347 Query: 346 VGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASP 405 G A P +PP P + Y + S + SS+ A+ P Sbjct: 348 KGPTLAPSPH-------SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400 Query: 406 ATAA------TLPVGTGQNASSVGAQLMGAS--SQPSEAMAPRTGPAQGGQVA--PCQPT 455 A+ A + P T + S+ + S SQ + P P G +A P Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG 460 Query: 456 GVPPATVGGVVQPCLGPAGA---------------GQPQSVPPPQMGGSGPLSAVPGG-P 499 PP+T G P Q Q G SGP PG P Sbjct: 461 PFPPST--GAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP--PPPGAFP 516 Query: 500 HAVVPGVPN--VPAAVPAPSVPSVSTTSVTMPNVPAPLAQ---SQQLSSHTPVSRSSSII 554 H + G + P A+ +PS+ S+ ++P P +Q SQ + PVS SS+ Sbjct: 517 HPLEGGSSHHAHPYAM-SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSS 575 Query: 555 QHVGLPLAPGTHSAPTSLPQ 574 P +H +P+ PQ Sbjct: 576 SSTSQGSYPCSHPSPSQGPQ 595 Score = 49.7 bits (117), Expect = 1e-05 Identities = 72/273 (26%), Positives = 97/273 (35%), Gaps = 68/273 (24%) Query: 384 HVAGLQPPSPAQPSST----GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAP 439 H L PPSP P ST A+ P + T TG +A P E Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVT---PTGYHA-------------PMEPPTS 203 Query: 440 RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSV---------PPP----QM 486 R A G P P P T G + P +GP G G SV PPP + Sbjct: 204 RMFQAPPG-APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISV 262 Query: 487 GGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTP 546 SG A P P G N+P+A P + P V+ PN+P P A P Sbjct: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVT------PNLPPPPAL-------RP 309 Query: 547 VSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPL 606 ++ +S+ +G PG +P ++ Q +G + K L P Sbjct: 310 LNNASASPPGLGAQPLPGHLPSPHAMGQG------------MGGLPPGPEKGPTLAPSPH 357 Query: 607 SLIAENKPVVKPPVADSLANPLQLTPMNSLATS 639 SL PP + S P P +S ++S Sbjct: 358 SL---------PPASSSAPAPPMRFPYSSSSSS 381 Score = 48.5 bits (114), Expect = 2e-05 Identities = 101/422 (23%), Positives = 131/422 (31%), Gaps = 96/422 (22%) Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFP 296 GPE G + + S LPP+ S PA P F + + SS+ PFP Sbjct: 345 GPEKGPTLAPSPHS-LPPA---SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400 Query: 297 GAA-------TGPQPMMAA--------AQPSQPQGA--GPGGQTLPPTNVTLAQPAMSLP 339 + + P P + QPS P A G PP LA Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG 460 Query: 340 PQPGPAVGAPAA------------QQPQQFAYPQPQ--------------IPPGHLLPVQ 373 P P P+ GA + QQ QQ Q Q PPG Sbjct: 461 PFP-PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519 Query: 374 PSGQSEYLQQHVAGLQ-------PPSPAQ--PSSTGAAASPATAATLPVGTGQNASSVGA 424 G S + + PP PA P + + S A PV + N+SS + Sbjct: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579 Query: 425 QLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGG------VVQPCLGPAGAGQP 478 Q S PS P+QG Q AP VP T + PAG Sbjct: 580 QGSYPCSHPS--------PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTA 631 Query: 479 QSVPPPQMGGSGPLSAV----------PGGPHAVVPGVPNVPAAVPAPSVP-SVSTTSVT 527 PP G P PG P + G P P+ P + S T Sbjct: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT 691 Query: 528 MPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAP--GTHSAPTSLPQSDLSQFQTQTQ 585 + P P A L S P P AP G + T + Q +++T Sbjct: 692 VGPGPLPPAGPSGLPSLPPP------------PAAPASGPPLSATQIKQEPAEEYETPES 739 Query: 586 PL 587 P+ Sbjct: 740 PV 741 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 75.9 bits (185), Expect = 1e-13 Identities = 123/533 (23%), Positives = 171/533 (32%), Gaps = 78/533 (14%) Query: 71 TLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAAT---- 126 ++++ G + P T P + G +A PAN V AL A+A+ Sbjct: 261 SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL 320 Query: 127 -SAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEY 185 + P PG P G G + P + PT S + + P R Sbjct: 321 GAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR-------- 372 Query: 186 YERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSS 245 +SS+ +A S ++ S AS P S + Sbjct: 373 ----------------FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPT 416 Query: 246 LTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSA---PLPPFPGAATGP 302 +VS PP K +Q P+ P Q PPPPP G +A S+A P PP GA + Sbjct: 417 SLSVSNQPP--KYTQ--PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472 Query: 303 QPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP 362 P ++ Q Q S PP PG A P A+P Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG-AFPHPLEGGSSHHAHPYA 531 Query: 363 QIP-----------PGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSST------------ 399 P P HL P P Q Y Q G S + SS+ Sbjct: 532 MSPSLGSLRPYPPGPAHLPP--PHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS 589 Query: 400 ---GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTG 456 G +P +P T +A+ ASS A GP G+ AP Sbjct: 590 PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP----- 644 Query: 457 VPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAP 516 P P P ++ PP G+ P P GP PG P V P P Sbjct: 645 -SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSP----PAGPGTFKPGSPTVG---PGP 696 Query: 517 SVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAP 569 P+ + ++P PA A LS+ + + P+ P +P Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749 Score = 65.5 bits (158), Expect = 2e-10 Identities = 93/329 (28%), Positives = 118/329 (35%), Gaps = 50/329 (15%) Query: 334 PAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPP-GHLLPVQPSGQSEYLQQHVAGLQPPS 392 P PP P P P +QP+ P P + P G+ P++P + Q G PP Sbjct: 161 PPPLFPPSPQPPDSTP--RQPEASFEPHPSVTPTGYHAPMEPPTSRMF--QAPPGAPPPH 216 Query: 393 PA-QPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQP--------------SEAM 437 P P TG S P G G ASSVG G P + Sbjct: 217 PQLYPGGTGGVLSGPPMG--PKGGGA-ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT 273 Query: 438 APRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQP---QSVPPPQMGGSGPLSA 494 P T P GG + P+ PPA V P L P A +P S PP +G PL Sbjct: 274 KPPTTPVGGGNL----PSAPPPANFPHVT-PNLPPPPALRPLNNASASPPGLGAQ-PLPG 327 Query: 495 VPGGPHAV-------VPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPV 547 PHA+ PG P P+P +++S P + P + S S+ Sbjct: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASS 387 Query: 548 SRSSSIIQHVGLPLAPGTHSAPTSLPQ----SDLSQFQTQTQPLVGQVDDTRRKSEPLPQ 603 S SSS P + S P S P S +Q TQP + P P Sbjct: 388 SSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL--PSQAVWSQGPPPP 445 Query: 604 PPLSLIAENK---PVVKPPV--ADSLANP 627 PP + N P PP A S A+P Sbjct: 446 PPYGRLLANSNAHPGPFPPSTGAQSTAHP 474 Score = 61.6 bits (148), Expect = 3e-09 Identities = 107/416 (25%), Positives = 136/416 (32%), Gaps = 58/416 (13%) Query: 253 PPSEKMSQPTPAQPQSFSVGQPQ--------PPPPPVGGAVAQSSA----------PLPP 294 PP+ +M Q P P P PP P GG A S P P Sbjct: 200 PPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTP 259 Query: 295 FPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQP 354 +++G P+ P G G PP N P + PP P A +A P Sbjct: 260 ISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNA-SASPP 318 Query: 355 QQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ-------PSSTGAAASPAT 407 A P PGHL GQ + GL PP P + P S A+S A Sbjct: 319 GLGAQPL----PGHLPSPHAMGQG------MGGL-PPGPEKGPTLAPSPHSLPPASSSAP 367 Query: 408 AATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQ 467 A + ++SS A +SS S A P Q P P PP T V Sbjct: 368 APPMRFPYSSSSSSSAAASSSSSSSSSSA-----SPFPASQALPSYPHSFPPPTSLSVSN 422 Query: 468 PCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVT 527 P QP S+P + GP P P+ + N A P P PS S Sbjct: 423 Q---PPKYTQP-SLPSQAVWSQGP---PPPPPYGRLLANSN---AHPGPFPPSTGAQSTA 472 Query: 528 MPNVPA--PLAQSQQLSSHTPVSRSSSIIQHVGL--PLAPGTHSAPTSLPQSDLSQFQTQ 583 P V Q QQ + QH G P PG P S + Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAM 532 Query: 584 TQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATS 639 + P +G + LP PP S ++ ++ P S +N T S S Sbjct: 533 S-PSLGSLRPYPPGPAHLP-PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCS 586 Score = 57.8 bits (138), Expect = 4e-08 Identities = 98/380 (25%), Positives = 133/380 (35%), Gaps = 56/380 (14%) Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFS----VGQP--QPPPPPVGGAVAQSSA 290 GP G A S P+ P P P S S G P +PP PVGG S+ Sbjct: 230 GPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAP 289 Query: 291 PLPPFPGAATG--PQPMMAAAQPSQPQGAGPGGQTLP---PTNVTLAQPAMSLPPQPGPA 345 P FP P P + + G G Q LP P+ + Q LP PGP Sbjct: 290 PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--PGPE 347 Query: 346 VGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASP 405 G A P +PP P + Y + S + SS+ A+ P Sbjct: 348 KGPTLAPSPH-------SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400 Query: 406 ATAA------TLPVGTGQNASSVGAQLMGAS--SQPSEAMAPRTGPAQGGQVA--PCQPT 455 A+ A + P T + S+ + S SQ + P P G +A P Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG 460 Query: 456 GVPPATVGGVVQPCLGPAGA---------------GQPQSVPPPQMGGSGPLSAVPGG-P 499 PP+T G P Q Q G SGP PG P Sbjct: 461 PFPPST--GAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP--PPPGAFP 516 Query: 500 HAVVPGVPN--VPAAVPAPSVPSVSTTSVTMPNVPAPLAQ---SQQLSSHTPVSRSSSII 554 H + G + P A+ +PS+ S+ ++P P +Q SQ + PVS SS+ Sbjct: 517 HPLEGGSSHHAHPYAM-SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSS 575 Query: 555 QHVGLPLAPGTHSAPTSLPQ 574 P +H +P+ PQ Sbjct: 576 SSTSQGSYPCSHPSPSQGPQ 595 Score = 49.7 bits (117), Expect = 1e-05 Identities = 72/273 (26%), Positives = 97/273 (35%), Gaps = 68/273 (24%) Query: 384 HVAGLQPPSPAQPSST----GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAP 439 H L PPSP P ST A+ P + T TG +A P E Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVT---PTGYHA-------------PMEPPTS 203 Query: 440 RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSV---------PPP----QM 486 R A G P P P T G + P +GP G G SV PPP + Sbjct: 204 RMFQAPPG-APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISV 262 Query: 487 GGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTP 546 SG A P P G N+P+A P + P V+ PN+P P A P Sbjct: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVT------PNLPPPPAL-------RP 309 Query: 547 VSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPL 606 ++ +S+ +G PG +P ++ Q +G + K L P Sbjct: 310 LNNASASPPGLGAQPLPGHLPSPHAMGQG------------MGGLPPGPEKGPTLAPSPH 357 Query: 607 SLIAENKPVVKPPVADSLANPLQLTPMNSLATS 639 SL PP + S P P +S ++S Sbjct: 358 SL---------PPASSSAPAPPMRFPYSSSSSS 381 Score = 48.5 bits (114), Expect = 2e-05 Identities = 101/422 (23%), Positives = 131/422 (31%), Gaps = 96/422 (22%) Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFP 296 GPE G + + S LPP+ S PA P F + + SS+ PFP Sbjct: 345 GPEKGPTLAPSPHS-LPPA---SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400 Query: 297 GAA-------TGPQPMMAA--------AQPSQPQGA--GPGGQTLPPTNVTLAQPAMSLP 339 + + P P + QPS P A G PP LA Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG 460 Query: 340 PQPGPAVGAPAA------------QQPQQFAYPQPQ--------------IPPGHLLPVQ 373 P P P+ GA + QQ QQ Q Q PPG Sbjct: 461 PFP-PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519 Query: 374 PSGQSEYLQQHVAGLQ-------PPSPAQ--PSSTGAAASPATAATLPVGTGQNASSVGA 424 G S + + PP PA P + + S A PV + N+SS + Sbjct: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579 Query: 425 QLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGG------VVQPCLGPAGAGQP 478 Q S PS P+QG Q AP VP T + PAG Sbjct: 580 QGSYPCSHPS--------PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTA 631 Query: 479 QSVPPPQMGGSGPLSAV----------PGGPHAVVPGVPNVPAAVPAPSVP-SVSTTSVT 527 PP G P PG P + G P P+ P + S T Sbjct: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT 691 Query: 528 MPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAP--GTHSAPTSLPQSDLSQFQTQTQ 585 + P P A L S P P AP G + T + Q +++T Sbjct: 692 VGPGPLPPAGPSGLPSLPPP------------PAAPASGPPLSATQIKQEPAEEYETPES 739 Query: 586 PL 587 P+ Sbjct: 740 PV 741 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 75.5 bits (184), Expect = 2e-13 Identities = 139/611 (22%), Positives = 205/611 (33%), Gaps = 130/611 (21%) Query: 249 VSQLPPSEKMSQPTPAQPQSFSVGQPQPPPP--PVGGAVAQSSAPLPPF----------- 295 V Q PP P P PQ P PPPP P A A S+P PPF Sbjct: 753 VPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSP-PPFIATQVPVLEPQ 811 Query: 296 -PGAATGP-----QPMMAAAQPS-QPQGAGPGGQTLPP-------------TNVTLAQP- 334 PG+ P QP++ QP P P + PP N QP Sbjct: 812 LPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPS 871 Query: 335 -----AMSLPPQPG-PAVGAPAAQQPQQFAYPQPQIPPGHLL-------PVQPSGQSEYL 381 A +LPP+P P +PA Q P PP LL P S Q + Sbjct: 872 RPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLY 931 Query: 382 QQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRT 441 Q + +QPP+P PS + P P + Q Q + P P+ Sbjct: 932 LQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQ-------QQLQQQPPPPPPPQPQP 984 Query: 442 GPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHA 501 P Q Q P +P + P +Q P G P PPP G P P P Sbjct: 985 PPQQQHQPPP-RPVHLQPMQFSTHIQQPPPPQGQQPPH--PPP---GQQPPPPQPAKPQQ 1038 Query: 502 VV------------PGVPNVPAAVPAP---------SVPSVSTTSVTMPNV--------- 531 V+ P P+P S++ S NV Sbjct: 1039 VIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRA 1098 Query: 532 -----PAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQP 586 P PL ++ H+P+ RS P +P P P+S + +P Sbjct: 1099 ASVVQPQPLVVVKEEKIHSPIIRSE--------PFSPSLRPEPPKHPESIKAPVHLPQRP 1150 Query: 587 LVGQVDDTRRKSEPLPQ--PPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIA 644 + VD R P Q PP ++K +P + L++ M S A+ V Sbjct: 1151 EMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLV---- 1206 Query: 645 IPVDGDEDRNPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYA 704 ++P+T +T K S ++ + E+ +K+ +A Sbjct: 1207 -------QKHPTTP------SSTAKSSSDSFEQFRRAA-----REKEEREKALKAQAEHA 1248 Query: 705 VREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQ 764 +E+ + +E+++ + ++L + A ++ +Q Q +Q QQ A +A Sbjct: 1249 EKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQ--QRQEQQQQQQQQAAAVAA 1306 Query: 765 PPQPTQPPQQP 775 P QP Sbjct: 1307 AATPQAQSSQP 1317 Score = 62.8 bits (151), Expect = 1e-09 Identities = 103/414 (24%), Positives = 140/414 (33%), Gaps = 73/414 (17%) Query: 256 EKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQ 315 ++M Q PQ QPPPPP Q P PP PS PQ Sbjct: 744 QQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPP----------------PSMPQ 787 Query: 316 GAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAY-PQPQIPPGHLLPVQP 374 A P ++ PP + P L PQ +V P Q + PQP++PP HL Sbjct: 788 QAAPAMKSSPPPFIATQVPV--LEPQLPGSVFDPIGHFTQPILHLPQPELPP-HLPQPPE 844 Query: 375 SGQSEYLQQHVAGLQPPS--------PAQPSSTGAAASPATAATLPVGTGQN-------- 418 +L QH A + PP+ P++PS+ AA P A V Sbjct: 845 HSTPPHLNQH-AVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQP 903 Query: 419 ----------------ASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATV 462 A + + M Q + + P T +V P +PP Sbjct: 904 PMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH 963 Query: 463 GGVVQPC-LGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGV--PNVPAAVPAPSVP 519 V Q P PQ PPPQ P V P + P P P P Sbjct: 964 PSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPP 1023 Query: 520 SVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQ 579 P P + Q H+P S L AP +P + +SQ Sbjct: 1024 PGQQPPPPQPAKPQQVIQHH----HSPRHHKSDPYSTGHLREAP----SPLMIHSPQMSQ 1075 Query: 580 FQTQTQPLVGQVDDTRRKSE----PLPQP-PLSLIAENK---PVVK-PPVADSL 624 FQ+ T Q + +K E + QP PL ++ E K P+++ P + SL Sbjct: 1076 FQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSL 1129 Score = 41.2 bits (95), Expect = 0.004 Identities = 52/195 (26%), Positives = 75/195 (38%), Gaps = 47/195 (24%) Query: 225 VVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGA 284 +++V A +G E+GT + VS +P + + S TP Q Q+ PQP PPPV Sbjct: 171 IMIVQAKGRGRGRKETGT--AKPGVSTVPNTTQAS--TPPQTQT-----PQPNPPPVQAT 221 Query: 285 V------------------------AQSSAPLPPFPGA--ATGPQPMMA-----AAQPSQ 313 Q+ P+PP P A PQP+ + AA P Q Sbjct: 222 PHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATP-Q 280 Query: 314 P----QGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPG-- 367 P +G T PT + SLPP+P + + P+ +P Sbjct: 281 PVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQ 340 Query: 368 HLLPVQPSGQSEYLQ 382 H P + S SE L+ Sbjct: 341 HPAPEKSSKVSEQLK 355 Score = 30.0 bits (66), Expect = 8.6 Identities = 42/184 (22%), Positives = 60/184 (32%), Gaps = 28/184 (15%) Query: 414 GTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPA 473 G G+ G G S+ P+ A Q Q P PP VQ P Sbjct: 178 GRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNP------PP------VQATPHPF 225 Query: 474 GAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPA 533 A P + + ++ VP P P VP P PAP+ V + + P Sbjct: 226 PAVTPDLIVQTPV-----MTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQ 280 Query: 534 PLAQS---QQLSSHTPVSRSSSIIQHVGLPLAPGT--------HSAPTSLPQSDLSQFQT 582 P+ ++ + T + I + LP P T S P P+ D+ Q Sbjct: 281 PVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQ 340 Query: 583 QTQP 586 P Sbjct: 341 HPAP 344 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 75.1 bits (183), Expect = 2e-13 Identities = 94/323 (29%), Positives = 116/323 (35%), Gaps = 61/323 (18%) Query: 254 PSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGP-QPMMAAAQPS 312 P + SQP PA+P + QP P+ P+ P PG P QP+ A P+ Sbjct: 319 PGHEKSQPGPAKPPA----QPSGLTKPLAQQPGTVKPPVQP-PGTTKPPAQPLGPAKPPA 373 Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPV 372 Q G+ P LAQP P VG AQQP P Q+ L Sbjct: 374 QQTGSEKPSSEQPGPK-ALAQP---------PGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423 Query: 373 QPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQ 432 QP QS A P+ G PA A G G+ + AQ G + Sbjct: 424 QPGLQSP------AKAPGPTKTPVQQPGPGKIPAQQA----GPGKTS----AQQTGPTKP 469 Query: 433 PSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPL 492 PS+ P P Q Q P +P PP G P P + PPPQ G Sbjct: 470 PSQLPGPAKPPPQ--QPGPAKP---PPQQPGSAKPPSQQPG-----STKPPPQQPG---- 515 Query: 493 SAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSS 552 P P PG P+ P + PS P+P S Q S+ PVS++ S Sbjct: 516 ---PAKPSPQQPGSTKPPSQQPGSAKPSAQQ--------PSPAKPSAQQST-KPVSQTGS 563 Query: 553 IIQHVGLPLAPGTHSAPTSLPQS 575 G PL P T S P S Sbjct: 564 -----GKPLQPPTVSPSAKQPPS 581 Score = 64.3 bits (155), Expect = 4e-10 Identities = 114/486 (23%), Positives = 156/486 (32%), Gaps = 90/486 (18%) Query: 229 VASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQS 288 +A G P + T V Q P + +Q A P S Q P PP + Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ--AGPGKTSAQQTGPTKPP--SQLPGP 476 Query: 289 SAPLPPFPGAATGPQPMMAAAQP--SQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAV 346 + P P PG A P +A+P QP P Q P + QP + PP P Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536 Query: 347 GAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHV---AGLQPPSPAQPSSTGAAA 403 P+AQQP A P Q PV +G + LQ + QPPS P T Sbjct: 537 AKPSAQQPSP-AKPSAQ---QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP-KTICPL 591 Query: 404 SPATAATLPV------GTGQNASSVGAQLMGASSQPS-------EAMAPRTGPAQGGQVA 450 T L V T + L G + P + + A GG +A Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651 Query: 451 PCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPP-------------PQMGGSGPLSAVP- 496 P + P V + QPQ P P+ PL P Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711 Query: 497 --GGPHAVVPGVPNV-----PAAVPAPSVPS-------------------------VSTT 524 G P A P PA PSVPS S++ Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS 771 Query: 525 SVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLA--------------PGTHSAPT 570 + T P++P+ QSQ TP ++ S P P + S Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831 Query: 571 SLP-QSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQ 629 S P S S+ Q Q P+ + + + +++ P+P + + P PP A Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT--PPGPRPTAGQTV 889 Query: 630 LTPMNS 635 TP S Sbjct: 890 PTPQQS 895 Score = 63.2 bits (152), Expect = 9e-10 Identities = 112/463 (24%), Positives = 156/463 (33%), Gaps = 59/463 (12%) Query: 230 ASMQGAHGPESGTDSSLTAVSQLPPSEKM--SQPTPAQPQSFSVGQPQPPPPPVGGAVAQ 287 A G+ P S A++Q P K QP PA+P + VG P+P G Q Sbjct: 373 AQQTGSEKPSSEQPGP-KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG---LQ 428 Query: 288 SSAPLP-PFPGAATGPQPMMAAAQPSQP--QGAGPGGQTLPPTNVTLAQPAMSLPPQPGP 344 S A P P P P AQ + P A G T PP+ L PA P QPGP Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ--LPGPAKPPPQQPGP 486 Query: 345 AV--------GAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQP 396 A P +QQP P Q P P QP QQ G PS QP Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ--PGSAKPSAQQP 544 Query: 397 SSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRT--------------- 441 S +A +T G+G+ + ++ QP P+T Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQP--PTVSPSAKQPPSQGLPKTICPLCNTTELLLHVP 602 Query: 442 GPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHA 501 A CQ T + G P L + + G G L+ VP P Sbjct: 603 EKANFNTCTECQTTVC--SLCGFNPNPHLTEVKEWLCLNCQMKRALG-GDLAPVPSSPQP 659 Query: 502 VVPGVPNVPAAVPAPSVPSVSTTS-------------VTMPNVPAPLAQSQQL-SSHTPV 547 + P + + S P TS P P PL + L S + Sbjct: 660 KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAK 719 Query: 548 SRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPL- 606 ++ + P P S P+ ++ ++ + + +V D S +P + Sbjct: 720 AKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIP 779 Query: 607 --SLIAENKPVVKPPVADSLANPLQLTPMNSLATSVF-SIAIP 646 + ++ + PP+ A P Q P S F S AIP Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822 Score = 54.7 bits (130), Expect = 3e-07 Identities = 92/388 (23%), Positives = 128/388 (32%), Gaps = 55/388 (14%) Query: 284 AVAQSSAPLP--PFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQ 341 A+ AP+P P P T P +A S PQ QT P + A P L Sbjct: 645 ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ----QTSPKKD---AAPKQDLSKA 697 Query: 342 PGPAVGAPAAQQPQQFAYPQP---QIPPGHLL-----PVQPSGQSEYLQQHVAGLQPPSP 393 P P P +QP P Q P L P +PS SE + VA +P P Sbjct: 698 PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP 757 Query: 394 AQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ 453 T S ++A T P S + + A ++ P G +V+P Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD 817 Query: 454 PTGVPPATVGGVVQPCLGPAGAGQPQ-SVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAA 512 +P + GP+ + Q V P Q + P +P Sbjct: 818 SKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT 877 Query: 513 VPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSH-------------TP------------- 546 P P P+ T T P P QS++ S + TP Sbjct: 878 PPGPR-PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936 Query: 547 --VSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQP 604 S++S++I G PG HS S P + + Q +QP Q P P P Sbjct: 937 SIFSQASNLISTAG---QPGPHS--QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP-PAP 990 Query: 605 PLSLIAENKPVVKPPVADSLANPLQLTP 632 S+ K K P A+ L + P Sbjct: 991 AKSIPV--KKETKAPAAEKLEPKAEQAP 1016 Score = 43.9 bits (102), Expect = 6e-04 Identities = 88/377 (23%), Positives = 124/377 (32%), Gaps = 50/377 (13%) Query: 250 SQLPPSEKMSQPTPAQPQSFS-------VGQPQPPPPPVGGAVAQSSAPLPPFPGAATGP 302 SQLP PA+P+ F QP PPPPP P PP P P Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP---------PPPPPPPPPPPPP 2424 Query: 303 QPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP 362 P+ P P LP +T+A P + P + P Sbjct: 2425 PPL--------PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT 2476 Query: 363 QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSV 422 +I PV P S + + P P++P P T T + Sbjct: 2477 RICTTAPPPVPPKPSS--IPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPT 2534 Query: 423 GAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVP--PATVGGVVQPCLGPAGAGQPQS 480 G L + + A P+ ++P P ++ P+ G P Sbjct: 2535 GLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTD 2594 Query: 481 VPPPQMGGSGPLSAVPGGPHAVVPGVPNVP--AAVPAP-----------SVPSVSTTSVT 527 Q S PL + +V P VP AV P ++ + S T VT Sbjct: 2595 SSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVT 2654 Query: 528 MPN--VPAPLAQSQQLS---SHTPVSRSSSIIQHVGL-PLAPGTHSAPTSLPQSDLSQFQ 581 P+ AP + +Q L+ S T VS + S VGL ++ P +L L + Q Sbjct: 2655 APSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQ 2714 Query: 582 TQTQ---PLVGQVDDTR 595 + LVG V D R Sbjct: 2715 YKEDGKLQLVGDVIDLR 2731 Score = 42.0 bits (97), Expect = 0.002 Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 25/180 (13%) Query: 241 GTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAAT 300 G S Q+ P +K +P AQ + +P P P G +P PP Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMPKG-------SPTPP------ 879 Query: 301 GPQPMMAAAQPSQPQGAGPGGQT----LPPTNVTLAQPAMSLPPQP---GPAVGAPAAQQ 353 GP+P P+ Q P Q+ L ++T A + PQ G G A+ Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939 Query: 354 PQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPV 413 Q PG P SG ++Q A QPP+ P + A PA A ++PV Sbjct: 940 SQASNLISTAGQPG---PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996 Score = 33.9 bits (76), Expect = 0.60 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 5/37 (13%) Query: 744 QLPTQQANPGSTSQQQAVIAQPPQ-----PTQPPQQP 775 ++P QQA PG TS QQ +PP PPQQP Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 75.1 bits (183), Expect = 2e-13 Identities = 94/323 (29%), Positives = 116/323 (35%), Gaps = 61/323 (18%) Query: 254 PSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGP-QPMMAAAQPS 312 P + SQP PA+P + QP P+ P+ P PG P QP+ A P+ Sbjct: 319 PGHEKSQPGPAKPPA----QPSGLTKPLAQQPGTVKPPVQP-PGTTKPPAQPLGPAKPPA 373 Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPV 372 Q G+ P LAQP P VG AQQP P Q+ L Sbjct: 374 QQTGSEKPSSEQPGPK-ALAQP---------PGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423 Query: 373 QPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQ 432 QP QS A P+ G PA A G G+ + AQ G + Sbjct: 424 QPGLQSP------AKAPGPTKTPVQQPGPGKIPAQQA----GPGKTS----AQQTGPTKP 469 Query: 433 PSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPL 492 PS+ P P Q Q P +P PP G P P + PPPQ G Sbjct: 470 PSQLPGPAKPPPQ--QPGPAKP---PPQQPGSAKPPSQQPG-----STKPPPQQPG---- 515 Query: 493 SAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSS 552 P P PG P+ P + PS P+P S Q S+ PVS++ S Sbjct: 516 ---PAKPSPQQPGSTKPPSQQPGSAKPSAQQ--------PSPAKPSAQQST-KPVSQTGS 563 Query: 553 IIQHVGLPLAPGTHSAPTSLPQS 575 G PL P T S P S Sbjct: 564 -----GKPLQPPTVSPSAKQPPS 581 Score = 64.3 bits (155), Expect = 4e-10 Identities = 114/486 (23%), Positives = 156/486 (32%), Gaps = 90/486 (18%) Query: 229 VASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQS 288 +A G P + T V Q P + +Q A P S Q P PP + Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ--AGPGKTSAQQTGPTKPP--SQLPGP 476 Query: 289 SAPLPPFPGAATGPQPMMAAAQP--SQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAV 346 + P P PG A P +A+P QP P Q P + QP + PP P Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536 Query: 347 GAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHV---AGLQPPSPAQPSSTGAAA 403 P+AQQP A P Q PV +G + LQ + QPPS P T Sbjct: 537 AKPSAQQPSP-AKPSAQ---QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP-KTICPL 591 Query: 404 SPATAATLPV------GTGQNASSVGAQLMGASSQPS-------EAMAPRTGPAQGGQVA 450 T L V T + L G + P + + A GG +A Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651 Query: 451 PCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPP-------------PQMGGSGPLSAVP- 496 P + P V + QPQ P P+ PL P Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711 Query: 497 --GGPHAVVPGVPNV-----PAAVPAPSVPS-------------------------VSTT 524 G P A P PA PSVPS S++ Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS 771 Query: 525 SVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLA--------------PGTHSAPT 570 + T P++P+ QSQ TP ++ S P P + S Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831 Query: 571 SLP-QSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQ 629 S P S S+ Q Q P+ + + + +++ P+P + + P PP A Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT--PPGPRPTAGQTV 889 Query: 630 LTPMNS 635 TP S Sbjct: 890 PTPQQS 895 Score = 63.2 bits (152), Expect = 9e-10 Identities = 112/463 (24%), Positives = 156/463 (33%), Gaps = 59/463 (12%) Query: 230 ASMQGAHGPESGTDSSLTAVSQLPPSEKM--SQPTPAQPQSFSVGQPQPPPPPVGGAVAQ 287 A G+ P S A++Q P K QP PA+P + VG P+P G Q Sbjct: 373 AQQTGSEKPSSEQPGP-KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG---LQ 428 Query: 288 SSAPLP-PFPGAATGPQPMMAAAQPSQP--QGAGPGGQTLPPTNVTLAQPAMSLPPQPGP 344 S A P P P P AQ + P A G T PP+ L PA P QPGP Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ--LPGPAKPPPQQPGP 486 Query: 345 AV--------GAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQP 396 A P +QQP P Q P P QP QQ G PS QP Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ--PGSAKPSAQQP 544 Query: 397 SSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRT--------------- 441 S +A +T G+G+ + ++ QP P+T Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQP--PTVSPSAKQPPSQGLPKTICPLCNTTELLLHVP 602 Query: 442 GPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHA 501 A CQ T + G P L + + G G L+ VP P Sbjct: 603 EKANFNTCTECQTTVC--SLCGFNPNPHLTEVKEWLCLNCQMKRALG-GDLAPVPSSPQP 659 Query: 502 VVPGVPNVPAAVPAPSVPSVSTTS-------------VTMPNVPAPLAQSQQL-SSHTPV 547 + P + + S P TS P P PL + L S + Sbjct: 660 KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAK 719 Query: 548 SRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPL- 606 ++ + P P S P+ ++ ++ + + +V D S +P + Sbjct: 720 AKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIP 779 Query: 607 --SLIAENKPVVKPPVADSLANPLQLTPMNSLATSVF-SIAIP 646 + ++ + PP+ A P Q P S F S AIP Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822 Score = 54.7 bits (130), Expect = 3e-07 Identities = 92/388 (23%), Positives = 128/388 (32%), Gaps = 55/388 (14%) Query: 284 AVAQSSAPLP--PFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQ 341 A+ AP+P P P T P +A S PQ QT P + A P L Sbjct: 645 ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ----QTSPKKD---AAPKQDLSKA 697 Query: 342 PGPAVGAPAAQQPQQFAYPQP---QIPPGHLL-----PVQPSGQSEYLQQHVAGLQPPSP 393 P P P +QP P Q P L P +PS SE + VA +P P Sbjct: 698 PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP 757 Query: 394 AQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ 453 T S ++A T P S + + A ++ P G +V+P Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD 817 Query: 454 PTGVPPATVGGVVQPCLGPAGAGQPQ-SVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAA 512 +P + GP+ + Q V P Q + P +P Sbjct: 818 SKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT 877 Query: 513 VPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSH-------------TP------------- 546 P P P+ T T P P QS++ S + TP Sbjct: 878 PPGPR-PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936 Query: 547 --VSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQP 604 S++S++I G PG HS S P + + Q +QP Q P P P Sbjct: 937 SIFSQASNLISTAG---QPGPHS--QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP-PAP 990 Query: 605 PLSLIAENKPVVKPPVADSLANPLQLTP 632 S+ K K P A+ L + P Sbjct: 991 AKSIPV--KKETKAPAAEKLEPKAEQAP 1016 Score = 43.9 bits (102), Expect = 6e-04 Identities = 88/377 (23%), Positives = 124/377 (32%), Gaps = 50/377 (13%) Query: 250 SQLPPSEKMSQPTPAQPQSFS-------VGQPQPPPPPVGGAVAQSSAPLPPFPGAATGP 302 SQLP PA+P+ F QP PPPPP P PP P P Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP---------PPPPPPPPPPPPP 2424 Query: 303 QPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP 362 P+ P P LP +T+A P + P + P Sbjct: 2425 PPL--------PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT 2476 Query: 363 QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSV 422 +I PV P S + + P P++P P T T + Sbjct: 2477 RICTTAPPPVPPKPSS--IPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPT 2534 Query: 423 GAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVP--PATVGGVVQPCLGPAGAGQPQS 480 G L + + A P+ ++P P ++ P+ G P Sbjct: 2535 GLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTD 2594 Query: 481 VPPPQMGGSGPLSAVPGGPHAVVPGVPNVP--AAVPAP-----------SVPSVSTTSVT 527 Q S PL + +V P VP AV P ++ + S T VT Sbjct: 2595 SSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVT 2654 Query: 528 MPN--VPAPLAQSQQLS---SHTPVSRSSSIIQHVGL-PLAPGTHSAPTSLPQSDLSQFQ 581 P+ AP + +Q L+ S T VS + S VGL ++ P +L L + Q Sbjct: 2655 APSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQ 2714 Query: 582 TQTQ---PLVGQVDDTR 595 + LVG V D R Sbjct: 2715 YKEDGKLQLVGDVIDLR 2731 Score = 42.0 bits (97), Expect = 0.002 Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 25/180 (13%) Query: 241 GTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAAT 300 G S Q+ P +K +P AQ + +P P P G +P PP Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMPKG-------SPTPP------ 879 Query: 301 GPQPMMAAAQPSQPQGAGPGGQT----LPPTNVTLAQPAMSLPPQP---GPAVGAPAAQQ 353 GP+P P+ Q P Q+ L ++T A + PQ G G A+ Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939 Query: 354 PQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPV 413 Q PG P SG ++Q A QPP+ P + A PA A ++PV Sbjct: 940 SQASNLISTAGQPG---PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996 Score = 33.9 bits (76), Expect = 0.60 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 5/37 (13%) Query: 744 QLPTQQANPGSTSQQQAVIAQPPQ-----PTQPPQQP 775 ++P QQA PG TS QQ +PP PPQQP Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 72.8 bits (177), Expect = 1e-12 Identities = 154/603 (25%), Positives = 201/603 (33%), Gaps = 108/603 (17%) Query: 187 ERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSL 246 E SD + + S Q E DS A + ++Q G S+ Sbjct: 142 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 201 Query: 247 TAVSQLPPSEKMSQPTPAQPQ-----SFSVGQPQPPPPPVGGAVAQSSAPL--------- 292 QLP T PQ S + QPQ P PV Q + L Sbjct: 202 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 261 Query: 293 -PPFPGAATGPQPMMAAA-QPSQPQGAGPG--GQTLPPTNVTLAQPAMSLPPQPGPAVGA 348 PP P QP+ +A QPS P A P GQ P + A P + P P P Sbjct: 262 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 321 Query: 349 PAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ--------PSSTG 400 P A Q Q P H P+ QS Q QP PA P +T Sbjct: 322 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 381 Query: 401 AAASPATAATL--PVGTGQNASSVGAQL-----MGASSQPSEAMAPRTGPAQGGQVAPCQ 453 PA A P +G + S+ A L + S S P P + Q Sbjct: 382 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 441 Query: 454 PTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGG--SGPLSAVPGGPHAVVPGVPNVPA 511 P PA P G Q Q++PPP +G P P A P VP P Sbjct: 442 PLPSSPAQ----------PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 491 Query: 512 AVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTS 571 + P+ PS ST P P AQ P S G + G+ + +S Sbjct: 492 PITPPTCPSTSTP----PAGPGTSAQP-------PCS---------GAAASGGSIAGGSS 531 Query: 572 LPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLT 631 P L Q + + L DD P P PP S P +P V D T Sbjct: 532 CP---LPTVQIKEEAL----DDAEEPESP-PPPPRS------PSPEPTVVD--------T 569 Query: 632 PMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDNKIE 691 P ++ ++ F + DR ++ + L SK + K E Sbjct: 570 PSHASQSARFYKHL------DRGYNSCARTDLYFMPLAGSK-------------LAKKRE 610 Query: 692 QAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQ-A 750 +A++ K REE E KE+ KE ER ERE SS+ +L Q + Sbjct: 611 EAIEKAKREAEQKAREEREREKEKEKER-EREREREREAERAAKASSSAHEGRLSDPQLS 669 Query: 751 NPG 753 PG Sbjct: 670 GPG 672 Score = 63.5 bits (153), Expect = 7e-10 Identities = 125/569 (21%), Positives = 188/569 (33%), Gaps = 82/569 (14%) Query: 2 SKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDES-RTEDVSSEIFDVSRATDYGPE 60 SK KKS ++ ++ + ++ + + D +E+ RT ++ ++SR P Sbjct: 70 SKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PS 127 Query: 61 EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST 120 E SS ++N+ G ++ N + + ++ + + + Sbjct: 128 EGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAL 187 Query: 121 LA-AAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGR 179 A T AP+ PG PQL + GP +A + PP + S P + Sbjct: 188 QAPTGVTPAPSSAPPGTPQL--PTPGPTPSATAVPPQGSPT---------ASQAPNQPQA 236 Query: 180 WTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPE 239 T + + L H L + G + HG Sbjct: 237 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG-- 294 Query: 240 SGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQP---PPPPVGGAVAQSSAPLPPFP 296 Q PP Q A P G PQP PP G ++P +P Sbjct: 295 -----------QGPPGPHSLQ---AGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340 Query: 297 GAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQ 356 + +A Q QP P Q LPP LA P + PP Sbjct: 341 HTSLQLPASQSALQSQQP----PREQPLPP--APLAMPHIKPPPTT-------------- 380 Query: 357 FAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLP---V 413 PQ P H P SG S + A L PP +P S+ + P +A P + Sbjct: 381 -PIPQLPAPQAHKHPPHLSGPSPFSMN--ANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 437 Query: 414 GTGQNASSVGAQLMGASSQPSEAMAPRTGPAQG-GQVA--------PCQPTGVPPATVGG 464 Q S AQ G + + P + P G QVA P P G PP T Sbjct: 438 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT 497 Query: 465 VVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGV---------PNVPAAVPA 515 PAG G S PP G + ++ GG +P V P + P Sbjct: 498 CPSTSTPPAGPG--TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP 555 Query: 516 PSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544 P P + T+ + P+ +QS + H Sbjct: 556 P--PRSPSPEPTVVDTPSHASQSARFYKH 582 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 72.8 bits (177), Expect = 1e-12 Identities = 154/603 (25%), Positives = 201/603 (33%), Gaps = 108/603 (17%) Query: 187 ERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSL 246 E SD + + S Q E DS A + ++Q G S+ Sbjct: 696 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755 Query: 247 TAVSQLPPSEKMSQPTPAQPQ-----SFSVGQPQPPPPPVGGAVAQSSAPL--------- 292 QLP T PQ S + QPQ P PV Q + L Sbjct: 756 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815 Query: 293 -PPFPGAATGPQPMMAAA-QPSQPQGAGPG--GQTLPPTNVTLAQPAMSLPPQPGPAVGA 348 PP P QP+ +A QPS P A P GQ P + A P + P P P Sbjct: 816 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 875 Query: 349 PAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ--------PSSTG 400 P A Q Q P H P+ QS Q QP PA P +T Sbjct: 876 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935 Query: 401 AAASPATAATL--PVGTGQNASSVGAQL-----MGASSQPSEAMAPRTGPAQGGQVAPCQ 453 PA A P +G + S+ A L + S S P P + Q Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995 Query: 454 PTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGG--SGPLSAVPGGPHAVVPGVPNVPA 511 P PA P G Q Q++PPP +G P P A P VP P Sbjct: 996 PLPSSPAQ----------PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045 Query: 512 AVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTS 571 + P+ PS ST P P AQ P S G + G+ + +S Sbjct: 1046 PITPPTCPSTSTP----PAGPGTSAQP-------PCS---------GAAASGGSIAGGSS 1085 Query: 572 LPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLT 631 P L Q + + L DD P P PP S P +P V D T Sbjct: 1086 CP---LPTVQIKEEAL----DDAEEPESP-PPPPRS------PSPEPTVVD--------T 1123 Query: 632 PMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDNKIE 691 P ++ ++ F + DR ++ + L SK + K E Sbjct: 1124 PSHASQSARFYKHL------DRGYNSCARTDLYFMPLAGSK-------------LAKKRE 1164 Query: 692 QAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQ-A 750 +A++ K REE E KE+ KE ER ERE SS+ +L Q + Sbjct: 1165 EAIEKAKREAEQKAREEREREKEKEKER-EREREREREAERAAKASSSAHEGRLSDPQLS 1223 Query: 751 NPG 753 PG Sbjct: 1224 GPG 1226 Score = 63.5 bits (153), Expect = 7e-10 Identities = 125/569 (21%), Positives = 188/569 (33%), Gaps = 82/569 (14%) Query: 2 SKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDES-RTEDVSSEIFDVSRATDYGPE 60 SK KKS ++ ++ + ++ + + D +E+ RT ++ ++SR P Sbjct: 624 SKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PS 681 Query: 61 EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST 120 E SS ++N+ G ++ N + + ++ + + + Sbjct: 682 EGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAL 741 Query: 121 LA-AAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGR 179 A T AP+ PG PQL + GP +A + PP + S P + Sbjct: 742 QAPTGVTPAPSSAPPGTPQL--PTPGPTPSATAVPPQGSPT---------ASQAPNQPQA 790 Query: 180 WTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPE 239 T + + L H L + G + HG Sbjct: 791 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG-- 848 Query: 240 SGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQP---PPPPVGGAVAQSSAPLPPFP 296 Q PP Q A P G PQP PP G ++P +P Sbjct: 849 -----------QGPPGPHSLQ---AGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894 Query: 297 GAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQ 356 + +A Q QP P Q LPP LA P + PP Sbjct: 895 HTSLQLPASQSALQSQQP----PREQPLPP--APLAMPHIKPPPTT-------------- 934 Query: 357 FAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLP---V 413 PQ P H P SG S + A L PP +P S+ + P +A P + Sbjct: 935 -PIPQLPAPQAHKHPPHLSGPSPFSMN--ANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991 Query: 414 GTGQNASSVGAQLMGASSQPSEAMAPRTGPAQG-GQVA--------PCQPTGVPPATVGG 464 Q S AQ G + + P + P G QVA P P G PP T Sbjct: 992 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT 1051 Query: 465 VVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGV---------PNVPAAVPA 515 PAG G S PP G + ++ GG +P V P + P Sbjct: 1052 CPSTSTPPAGPG--TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP 1109 Query: 516 PSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544 P P + T+ + P+ +QS + H Sbjct: 1110 P--PRSPSPEPTVVDTPSHASQSARFYKH 1136 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 72.8 bits (177), Expect = 1e-12 Identities = 154/603 (25%), Positives = 201/603 (33%), Gaps = 108/603 (17%) Query: 187 ERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSL 246 E SD + + S Q E DS A + ++Q G S+ Sbjct: 696 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755 Query: 247 TAVSQLPPSEKMSQPTPAQPQ-----SFSVGQPQPPPPPVGGAVAQSSAPL--------- 292 QLP T PQ S + QPQ P PV Q + L Sbjct: 756 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815 Query: 293 -PPFPGAATGPQPMMAAA-QPSQPQGAGPG--GQTLPPTNVTLAQPAMSLPPQPGPAVGA 348 PP P QP+ +A QPS P A P GQ P + A P + P P P Sbjct: 816 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 875 Query: 349 PAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ--------PSSTG 400 P A Q Q P H P+ QS Q QP PA P +T Sbjct: 876 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935 Query: 401 AAASPATAATL--PVGTGQNASSVGAQL-----MGASSQPSEAMAPRTGPAQGGQVAPCQ 453 PA A P +G + S+ A L + S S P P + Q Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995 Query: 454 PTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGG--SGPLSAVPGGPHAVVPGVPNVPA 511 P PA P G Q Q++PPP +G P P A P VP P Sbjct: 996 PLPSSPAQ----------PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045 Query: 512 AVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTS 571 + P+ PS ST P P AQ P S G + G+ + +S Sbjct: 1046 PITPPTCPSTSTP----PAGPGTSAQP-------PCS---------GAAASGGSIAGGSS 1085 Query: 572 LPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLT 631 P L Q + + L DD P P PP S P +P V D T Sbjct: 1086 CP---LPTVQIKEEAL----DDAEEPESP-PPPPRS------PSPEPTVVD--------T 1123 Query: 632 PMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDNKIE 691 P ++ ++ F + DR ++ + L SK + K E Sbjct: 1124 PSHASQSARFYKHL------DRGYNSCARTDLYFMPLAGSK-------------LAKKRE 1164 Query: 692 QAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQ-A 750 +A++ K REE E KE+ KE ER ERE SS+ +L Q + Sbjct: 1165 EAIEKAKREAEQKAREEREREKEKEKER-EREREREREAERAAKASSSAHEGRLSDPQLS 1223 Query: 751 NPG 753 PG Sbjct: 1224 GPG 1226 Score = 63.5 bits (153), Expect = 7e-10 Identities = 125/569 (21%), Positives = 188/569 (33%), Gaps = 82/569 (14%) Query: 2 SKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDES-RTEDVSSEIFDVSRATDYGPE 60 SK KKS ++ ++ + ++ + + D +E+ RT ++ ++SR P Sbjct: 624 SKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PS 681 Query: 61 EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST 120 E SS ++N+ G ++ N + + ++ + + + Sbjct: 682 EGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAL 741 Query: 121 LA-AAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGR 179 A T AP+ PG PQL + GP +A + PP + S P + Sbjct: 742 QAPTGVTPAPSSAPPGTPQL--PTPGPTPSATAVPPQGSPT---------ASQAPNQPQA 790 Query: 180 WTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPE 239 T + + L H L + G + HG Sbjct: 791 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG-- 848 Query: 240 SGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQP---PPPPVGGAVAQSSAPLPPFP 296 Q PP Q A P G PQP PP G ++P +P Sbjct: 849 -----------QGPPGPHSLQ---AGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894 Query: 297 GAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQ 356 + +A Q QP P Q LPP LA P + PP Sbjct: 895 HTSLQLPASQSALQSQQP----PREQPLPP--APLAMPHIKPPPTT-------------- 934 Query: 357 FAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLP---V 413 PQ P H P SG S + A L PP +P S+ + P +A P + Sbjct: 935 -PIPQLPAPQAHKHPPHLSGPSPFSMN--ANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991 Query: 414 GTGQNASSVGAQLMGASSQPSEAMAPRTGPAQG-GQVA--------PCQPTGVPPATVGG 464 Q S AQ G + + P + P G QVA P P G PP T Sbjct: 992 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT 1051 Query: 465 VVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGV---------PNVPAAVPA 515 PAG G S PP G + ++ GG +P V P + P Sbjct: 1052 CPSTSTPPAGPG--TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP 1109 Query: 516 PSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544 P P + T+ + P+ +QS + H Sbjct: 1110 P--PRSPSPEPTVVDTPSHASQSARFYKH 1136 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 72.4 bits (176), Expect = 2e-12 Identities = 115/423 (27%), Positives = 148/423 (34%), Gaps = 53/423 (12%) Query: 230 ASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQ---PQSFSVGQPQPPPPPVGGAVA 286 ++ G +DS + S + S + P+PAQ S G P P GA Sbjct: 614 STFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQ 673 Query: 287 QSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAV 346 Q +A PG G P A Q P P P S P GP Sbjct: 674 QPTAA----PGLPVGSVPAPACPPSLQQHFPDPAMSFAP------VLPPPSTPMPTGPGQ 723 Query: 347 GAPAAQQPQQFAYPQP---QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAA 403 AP QQP A P P + P ++P+QP + H+ PP A S GA A Sbjct: 724 PAPPGQQPPPLAQPTPLPQVLAPQPVVPLQP------VPPHL----PPYLAPASQVGAPA 773 Query: 404 SPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVG 463 +P Q + V Q+ P + P P G P +P ATV Sbjct: 774 Q-LKPLQMPQAPLQPLAQVPPQM------PPIPVVPPITPLAGIDGLPPALPDLPTATVP 826 Query: 464 GVVQP-CLGPAGAGQPQSVPPPQMGGSGPLSAV-----PGGPHAVV--PGVPNVPAAVP- 514 V P PA + P P + PL AV PG P A+ VPN PA +P Sbjct: 827 PVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPL 886 Query: 515 -APSVPSVSTTSV-----TMPNVPA-PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHS 567 A + P V+ S+ +P P P A Q + P S ++ P P Sbjct: 887 LAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPP 946 Query: 568 APTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKP-PVADSLAN 626 PT PQ L T V TR LP P+ +PV+ P P Sbjct: 947 QPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPM---LPPQPVLPPQPALPVRPE 1003 Query: 627 PLQ 629 PLQ Sbjct: 1004 PLQ 1006 Score = 64.7 bits (156), Expect = 3e-10 Identities = 92/352 (26%), Positives = 122/352 (34%), Gaps = 36/352 (10%) Query: 238 PESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQP----PPPPVGGAVAQSSAPLP 293 P +G D A+ LP + + P PQ FS P P PP A+ + LP Sbjct: 806 PLAGIDGLPPALPDLPTA---TVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLP 862 Query: 294 PFPGA------------ATGPQPMMAAAQPS------QPQGAGPGGQTLPPTNVTLAQPA 335 PGA A P++A A P A GQ + P P Sbjct: 863 HPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPT 922 Query: 336 MSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPS--GQSEYLQQHVAGLQPPSP 393 +PP P V A PQ PQP +PP +LP QP+ Q Q QP P Sbjct: 923 -DVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLP 981 Query: 394 AQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ 453 QP P A LPV + Q A++ S+ + P A Sbjct: 982 PQPMLPPQPVLPPQPA-LPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVP 1040 Query: 454 PTGVPPATVGGVVQP-CLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAA 512 VPPA V P L PA P S + +VP ++P PA Sbjct: 1041 TVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLP-----PAN 1095 Query: 513 VPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPG 564 P P P +++ T+ P+ Q +Q S P S + G + G Sbjct: 1096 PPLPGGPGIASPCPTVQLTVEPV-QEEQASQDKPPGLPQSCESYGGSDVTSG 1146 Score = 63.2 bits (152), Expect = 9e-10 Identities = 95/354 (26%), Positives = 121/354 (34%), Gaps = 47/354 (13%) Query: 244 SSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAP--LPPFPGAATG 301 S + A +QL P + P Q P P PP+ P LP P A Sbjct: 767 SQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVP 826 Query: 302 PQPMMAAAQPSQ--PQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAY 359 P P P+ P A P LPP + L A+ LP PG AP A + Sbjct: 827 PVPPPQYFSPAVILPSLAAP----LPPASPALPLQAVKLPHPPG----APLAMPCRTIVP 878 Query: 360 PQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNA 419 P P LL V P G + P P P++ A P P T QN Sbjct: 879 NAPATIP--LLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMA-PTDVPPSPHHTVQNM 935 Query: 420 SSVGAQ--LMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQ 477 + Q L + P + + P V P QPT P QP L P Sbjct: 936 RATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPP--------QPVLPPQPMLP 987 Query: 478 PQSVPPPQMGGSGPLSAVPGGPH-------AVVPG-----------VPNVPAAVPAPSVP 519 PQ V PPQ + P+ P PH A PG +V A VP VP Sbjct: 988 PQPVLPPQP--ALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP 1045 Query: 520 SVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 + S +P V P A + ++ S+ +Q V P T P + P Sbjct: 1046 PAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSV--PTQTATLLPPANPP 1097 Score = 49.3 bits (116), Expect = 1e-05 Identities = 75/309 (24%), Positives = 106/309 (34%), Gaps = 46/309 (14%) Query: 230 ASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSS 289 AS G G G S L + P +E P QP VG P P + +S Sbjct: 1414 ASQAGGPGTPQGLTSELE--TSQPLAETHEAPLAVQP--LVVGLAPCTPAPEAASTRDAS 1469 Query: 290 APLPPFPGAATGPQPMMAAAQPSQPQ-----GAGPGGQTLPPTNVTLAQPAMSLPPQPGP 344 AP P P A P P QP+ Q A G +L + + ++PPQP Sbjct: 1470 APREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPS 1529 Query: 345 AVGAPAAQQPQQFAYP----------------QPQIPPGHLLPVQP--SGQSEYLQQHVA 386 A+ + P + + Q +P P G ++ + + Sbjct: 1530 ALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLR 1589 Query: 387 GLQPPSPAQPSSTGAAASPATAAT----LP---VGTGQNASSVGAQL-MGASSQPSEAMA 438 G QP S P A + LP V + A + GA + G SS + + Sbjct: 1590 GDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESS 1649 Query: 439 PRT---------GPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAG-AGQPQSVPPP-QMG 487 PR+ A V P P VP V+P G AG+ + PPP MG Sbjct: 1650 PRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMG 1709 Query: 488 GSGPLSAVP 496 G ++ P Sbjct: 1710 TVGGQASHP 1718 Score = 47.8 bits (112), Expect = 4e-05 Identities = 57/230 (24%), Positives = 77/230 (33%), Gaps = 35/230 (15%) Query: 238 PESGTDSSLTAVSQLPP-------------SEKMSQPTPAQPQSFSVGQPQPPPPPVGGA 284 PE+ S +S LPP S K A Q S P PP Sbjct: 1324 PEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAP 1383 Query: 285 VAQSSAPLPPFP--GAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQP 342 +A SS P+ P GAA M A + Q GPG + + +QP P Sbjct: 1384 LAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAP 1443 Query: 343 ----------GPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPS 392 P AP A + + P+ +PP P SG + L P+ Sbjct: 1444 LAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQ------PALGQPA 1497 Query: 393 PAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTG 442 P P++ GA + AT + + +V Q A E PR G Sbjct: 1498 PLLPAAVGA----VSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVG 1543 Score = 46.2 bits (108), Expect = 1e-04 Identities = 77/289 (26%), Positives = 112/289 (38%), Gaps = 55/289 (19%) Query: 391 PSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPS----EAMAPRTGPAQ- 445 P+P P S+ P ++LP Q+++ QL + QPS + + + GP+ Sbjct: 1322 PAPEAPESS----PPLPLSSLPPEASQDSAPYKDQL-SSKEQPSFLASQQLLSQAGPSNP 1376 Query: 446 -GGQVAPCQPTGVP----------PATVGGVVQPCLGPA----GAGQPQSVPPPQMGGSG 490 G AP P+ P PAT + +P G A G G PQ + ++ S Sbjct: 1377 PGAPPAPLAPSSPPVTALPQDGAAPAT-STMPEPASGTASQAGGPGTPQGLTS-ELETSQ 1434 Query: 491 PLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRS 550 PL+ P AV P V + PAP + ST + P P P + + S H+ + Sbjct: 1435 PLAETHEAPLAVQPLVVGLAPCTPAPE--AASTRDASAPREPLP-PPAPEPSPHSGTPQP 1491 Query: 551 SSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIA 610 + LP A G S TS Q + PL V PQPP +L + Sbjct: 1492 ALGQPAPLLPAAVGAVSLATS---------QLPSPPLGPTVP---------PQPPSALES 1533 Query: 611 ENK-PVVKPPVADSLANPLQ-----LTPMNSLATSVFSIAIPVD-GDED 652 + + P + DS L L + TS S PV+ GD D Sbjct: 1534 DGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRD 1582 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 72.0 bits (175), Expect = 2e-12 Identities = 148/638 (23%), Positives = 211/638 (33%), Gaps = 107/638 (16%) Query: 36 PDESRTEDVSSEIFDVSRATDYGPEEVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLA 95 P S ++S+ F S + P + + T + V G +L+ + + Sbjct: 678 PVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGV---SLVYSDKKS 734 Query: 96 AAAAAPANGGGVVSARSVSGALASTLAAAATS------------APAP--------GAPG 135 AAA +PA V+G L T+ A + APAP GAPG Sbjct: 735 AAATSPA-------PHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPG 787 Query: 136 GPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVL 195 G AGS AG + P G + G T ++Y + Sbjct: 788 GGTTAGSGAGAGSGPNGPVPLGILQ----------PGALGKAGGITQVQYILPTLPQQLQ 837 Query: 196 TRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPS 255 G A S S++ P + T+ + A + P Sbjct: 838 VAPAPAPA------------PGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPG 885 Query: 256 EKMSQPTPAQP--QSFSVGQPQPPPPP------VGGAVAQSSAPLPPFPGAATGPQPMMA 307 + Q P+ P ++ SV Q PPP G + +AP G G QP+ Sbjct: 886 IPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAG-QPLPL 944 Query: 308 AAQP-SQP--QGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP-- 362 + P S P GA P + + T V ++ P+ +PP + P +Q PQ+ P Sbjct: 945 VSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQ-PQKVLLPSSTR 1003 Query: 363 ----QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQN 418 Q GH LP+ S S V P S T S A P+ + Sbjct: 1004 ITYVQSAGGHALPLGTSPASSQAGT-VTSYGPTSSVALGFTSLGPS-GPAFVQPLLSAGQ 1061 Query: 419 ASSVGAQLMGASSQPSEAMAPRTGPAQG--------GQVAP------CQPTGVPPATVGG 464 A + +G S PS + P G G AP QP+ PP+ V Sbjct: 1062 APLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYT 1121 Query: 465 VVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAV-PAPSVPSVST 523 V PA P+ P P P S P + P A P+P P Sbjct: 1122 VATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAP--QK 1179 Query: 524 TSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQT- 582 + ++P ++ P R PL PG PT+ P+S+L T Sbjct: 1180 VKAAIASIPVGSFEAGASGRPGPAPRQ---------PLEPGPVREPTA-PESELEGQPTP 1229 Query: 583 -QTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPP 619 PL T R S PLP P AE + K P Sbjct: 1230 PAPPPLPETWTPTARSSPPLPPP-----AEERTSAKGP 1262 Score = 71.6 bits (174), Expect = 3e-12 Identities = 135/554 (24%), Positives = 193/554 (34%), Gaps = 108/554 (19%) Query: 77 DAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGG 136 D E PG P + +AP++ ++ S S A + +L + A G Sbjct: 511 DPEPPGPPDPPVAFG---KGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQ--- 564 Query: 137 PQLAGSSAGPVTAAP--SQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSV 194 GS+AGP+ P + P T S R + +D + +RR R + E S + Sbjct: 565 ----GSTAGPLRPPPPGAGGPATPSKATRFLPMDPAT---FRRKRPESVGGLEPPGPSVI 617 Query: 195 LT--RSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQL 252 G I + E G GA S + P S +++ Sbjct: 618 AAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVR 677 Query: 253 PPSEKMSQPTPAQPQSFSV-GQPQPPPPPVGGAVAQ--------SSAPL-------PPFP 296 P S S P P + F G+ + P GA + +PL Sbjct: 678 PVS---STPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKS 734 Query: 297 GAATGPQPMMAAAQPSQPQGAGPGGQTL----PPTNVTLAQPAMSLPPQPGPAVGAPAAQ 352 AAT P P + A G P T P A PA+ Q P G A Sbjct: 735 AAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGS 794 Query: 353 QPQQFAYPQPQIPPGHLLP--VQPSG---QSEYL------QQHVAGLQPPSPAQPSSTGA 401 + P +P G L P + +G Q +Y+ Q VA P+P ++ + Sbjct: 795 GAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPS 854 Query: 402 AASPATAA--TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPP 459 +P T+ TLP GT N + A T P G + P+ PP Sbjct: 855 GPAPTTSIRFTLPPGTSTNGKVLAA----------------TAPTPGIPILQSVPSAPPP 898 Query: 460 ATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSV- 518 + QSV P Q + PGG ++PG VP A P+ SV Sbjct: 899 -----------------KAQSVSPVQ-------APPPGGSAQLLPGKVLVPLAAPSMSVR 934 Query: 519 --------PSVSTT-SVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAP 569 P VS SV + N P ++ QL+ PVS S ++ PL+P T P Sbjct: 935 GGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTP-VPVSTPSGLVP----PLSPATLPGP 989 Query: 570 TSLPQSDLSQFQTQ 583 TS PQ L T+ Sbjct: 990 TSQPQKVLLPSSTR 1003 Score = 60.5 bits (145), Expect = 6e-09 Identities = 154/675 (22%), Positives = 214/675 (31%), Gaps = 137/675 (20%) Query: 32 SLDDPDESRTEDVSSEIFDVSRATDYGPEEVCERSSS--EETLNNVGDAETPGTVSPNLL 89 S+ + + VSSE+ V+ T + SSS E L+ VG PG+ P Sbjct: 299 SMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGG---PGSARPRAF 355 Query: 90 LDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAP----GAPGGPQLAGSSAG 145 + + + GG V ++++ A+ S P P GAPG P A G Sbjct: 356 ------SHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPG-PFAAPGEGG 408 Query: 146 PVTAAPSQP--PTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIR 203 + A P PT S R D S E M E + D V+ G Sbjct: 409 ALAATGRPPLLPTRASRSQRAASEDMTSDEER-------MVICEEEGDDDVIADDGFGTT 461 Query: 204 HSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTP 263 + DS G + G PE S + S P Sbjct: 462 DIDLKCKERVTDSESGDSSGE------------DPEGNKGFGRKVFSPVIRSSFTHCRPP 509 Query: 264 AQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQT 323 P+ P PP PPV SAP +A+ P A+A S G+G T Sbjct: 510 LDPEP-----PGPPDPPVAFGKGYGSAP----SSSASSPASSSASAATSFSLGSG----T 556 Query: 324 LPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQ 383 A L P P P G PA LP+ P+ + Sbjct: 557 FKAQESGQGSTAGPLRPPP-PGAGGPATPSKAT-----------RFLPMDPATFRRKRPE 604 Query: 384 HVAGLQPPSP----AQPS---------------------------------STGAAASPA 406 V GL+PP P A PS + GA A+P Sbjct: 605 SVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPL 664 Query: 407 T--AATLPVGTGQNASSVGAQLMG--------ASSQPSEAMAPRTGPAQGGQVAPCQPTG 456 + AAT+ + SS + A + P++ RT G +V P G Sbjct: 665 SRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLG 724 Query: 457 VPPATVGGVVQPCLGPAGAGQPQSVPPPQMG--GSGP------LSAVPGGPHAVVPGVPN 508 V PA P V P +G G P L PG P V Sbjct: 725 VSLVYSDKKSAAATSPA----PHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQF 780 Query: 509 VPAAVPAPSVPSVSTTSV-TMPNVPAPLA--QSQQLSSHTPVSRSSSIIQHVGLPL---- 561 + P + S + PN P PL Q L +++ I+ + L Sbjct: 781 IAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAP 840 Query: 562 ----APGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVK 617 APGT +A S P + + + P + P P P I ++ P Sbjct: 841 APAPAPGTKAAAPSGP-APTTSIRFTLPPGTSTNGKVLAATAPTPGIP---ILQSVPSAP 896 Query: 618 PPVADSLANPLQLTP 632 PP A S+ +P+Q P Sbjct: 897 PPKAQSV-SPVQAPP 910 Score = 45.8 bits (107), Expect = 2e-04 Identities = 54/211 (25%), Positives = 71/211 (33%), Gaps = 39/211 (18%) Query: 240 SGTDSSLTAVSQLPPSEKMSQPTPAQP--------QSFSVGQP--QPPPP---------- 279 S T + T + + PP+ + P P P ++S+ P Q P P Sbjct: 1125 STTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAI 1184 Query: 280 ---PVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAM 336 PVG A +S P P P P+ P P PP T A Sbjct: 1185 ASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTAR 1244 Query: 337 SLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPA-- 394 S PP P PA +A+ P+ A P +P Q L+ PPSPA Sbjct: 1245 SSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQG------LENRGEPPTPPSPAPA 1298 Query: 395 --------QPSSTGAAASPATAATLPVGTGQ 417 SS+G AA GTG+ Sbjct: 1299 PAVAPGGSSESSSGRAAGDTPERKEAAGTGK 1329 Score = 45.1 bits (105), Expect = 3e-04 Identities = 74/299 (24%), Positives = 101/299 (33%), Gaps = 43/299 (14%) Query: 235 AHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQ----PQPPPPPVGGAVAQSSA 290 ++GP S T++ P+ + Q + GQ P P P A Sbjct: 1031 SYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGP 1090 Query: 291 PLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQ--PGPAVGA 348 + F + P AQPSQ A P T+ T PA ++ P+ P PA Sbjct: 1091 VITAFYSGSPAPTSSAPLAQPSQ---APPSLVYTVATSTT--PPAATILPKGPPAPATAT 1145 Query: 349 PAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATA 408 PA P P +G Y L P +PS A Sbjct: 1146 PAPTSP---------------FPSATAGSMTY------SLVAPKAQRPSPKAPQKVKAAI 1184 Query: 409 ATLPVGTGQNASSVGAQLMGASSQPSEAMAPR--TGPAQ--GGQVAPCQPTGVPPA-TVG 463 A++PVG+ + +S + A QP E R T P GQ P P +P T Sbjct: 1185 ASIPVGSFEAGAS--GRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPT 1242 Query: 464 GVVQPCLGPAGAGQPQSVPPPQMGGSGPLSA----VPGGPHAVVPGVPNVPAAVPAPSV 518 P L P + + P M P S+ VPG P P+ PAP+V Sbjct: 1243 ARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAV 1301 Score = 43.1 bits (100), Expect = 0.001 Identities = 34/111 (30%), Positives = 38/111 (34%), Gaps = 28/111 (25%) Query: 256 EKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQ 315 +K+ Q Q P P PPP G A A + P P A GP P PS Sbjct: 1516 QKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPA-----PTPSPAGGPDP----TSPSSDS 1566 Query: 316 GAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPP 366 G LPP PP+ GP QP PQP PP Sbjct: 1567 GTAQAAPPLPP------------PPESGPG-------QPGWEGAPQPSPPP 1598 Score = 41.2 bits (95), Expect = 0.004 Identities = 29/87 (33%), Positives = 35/87 (40%), Gaps = 16/87 (18%) Query: 247 TAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGG----------AVAQSSAPLPPFP 296 T Q P +E P P P + + P P P P GG AQ++ PLPP P Sbjct: 1523 TPTEQPPGAEA---PLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPP 1579 Query: 297 GAATGPQPMMAAAQPSQPQGAGPGGQT 323 + G A QPS P PG T Sbjct: 1580 ESGPGQPGWEGAPQPSPPP---PGPST 1603 Score = 35.4 bits (80), Expect = 0.20 Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 3/73 (4%) Query: 387 GLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQG 446 G + P P P TG AA+PA + P G G + +S + A + P P +GP Q Sbjct: 1530 GAEAPLPVPPP-TGTAAAPAPTPS-PAG-GPDPTSPSSDSGTAQAAPPLPPPPESGPGQP 1586 Query: 447 GQVAPCQPTGVPP 459 G QP+ PP Sbjct: 1587 GWEGAPQPSPPPP 1599 Score = 33.9 bits (76), Expect = 0.60 Identities = 33/111 (29%), Positives = 41/111 (36%), Gaps = 12/111 (10%) Query: 52 SRATDYGPEEVCERSSSEETLNNVGDAETPGTVSPNLLLD-------GQLAAAAAAPANG 104 +R D P +VC + E + A TP P G AA A P+ Sbjct: 1495 ARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPA 1554 Query: 105 GGV----VSARSVSGALASTLAAAATSAPA-PGAPGGPQLAGSSAGPVTAA 150 GG S+ S + A L S P PG G PQ + GP TAA Sbjct: 1555 GGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAA 1605 Score = 31.6 bits (70), Expect = 3.0 Identities = 26/76 (34%), Positives = 29/76 (38%), Gaps = 8/76 (10%) Query: 454 PTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSG----PLSAVP-GGPHAVVPGVPN 508 P VPP T G P P+ AG P P G+ PL P GP PG Sbjct: 1534 PLPVPPPT-GTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQ--PGWEG 1590 Query: 509 VPAAVPAPSVPSVSTT 524 P P P PS + T Sbjct: 1591 APQPSPPPPGPSTAAT 1606 Score = 31.2 bits (69), Expect = 3.9 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 3/65 (4%) Query: 223 GSVVVVVASMQGAHGPESGTDSSLTAVSQL-PPSEKMSQPTPAQPQSFSVGQPQPPPPPV 281 G+ + A GP+ + SS + +Q PP + P QP G PQP PPP Sbjct: 1542 GTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGW--EGAPQPSPPPP 1599 Query: 282 GGAVA 286 G + A Sbjct: 1600 GPSTA 1604 Score = 30.0 bits (66), Expect = 8.6 Identities = 24/94 (25%), Positives = 29/94 (30%), Gaps = 3/94 (3%) Query: 274 PQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQ 333 P P P V + AQ A P + P A A P G G PP Sbjct: 46 PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPES 105 Query: 334 PAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPG 367 P P P P + + P + PPG Sbjct: 106 PG---PGPPHPLGVVESGKGPPPTTEEEASGPPG 136 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.125 0.359 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,916,386 Number of Sequences: 37866 Number of extensions: 2766588 Number of successful extensions: 40166 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 462 Number of HSP's successfully gapped in prelim test: 2325 Number of HSP's that attempted gapping in prelim test: 16485 Number of HSP's gapped (non-prelim): 15153 length of query: 780 length of database: 18,247,518 effective HSP length: 110 effective length of query: 670 effective length of database: 14,082,258 effective search space: 9435112860 effective search space used: 9435112860 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.