Guide to the Human Genome
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Search of human proteins with 7662236

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
         (780 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662236 TSC22 domain family, member 2 [Homo sapiens]              1548   0.0  
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]   252   8e-67
gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens]     120   4e-27
gi|13569901 TSC22 domain family, member 4 [Homo sapiens]              117   5e-26
gi|37622901 TSC22 domain family, member 3 isoform 2 [Homo sapiens]    108   1e-23
gi|37622903 TSC22 domain family, member 3 isoform 1 [Homo sapiens]    107   3e-23
gi|163965366 nascent polypeptide-associated complex alpha subuni...   101   3e-21
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    94   6e-19
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    91   4e-18
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    88   3e-17
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             87   6e-17
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    86   1e-16
gi|160707881 formin 2 [Homo sapiens]                                   83   9e-16
gi|62865625 TSC22 domain family, member 3 isoform 3 [Homo sapiens]     81   3e-15
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    79   2e-14
gi|116284392 mucin 2 precursor [Homo sapiens]                          79   2e-14
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    79   2e-14
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         78   3e-14
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     77   6e-14
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    77   8e-14
gi|55750053 atrophin-1 [Homo sapiens]                                  76   1e-13
gi|55750041 atrophin-1 [Homo sapiens]                                  76   1e-13
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    75   2e-13
gi|150170670 piccolo isoform 2 [Homo sapiens]                          75   2e-13
gi|150378539 piccolo isoform 1 [Homo sapiens]                          75   2e-13
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          73   1e-12
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          73   1e-12
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          73   1e-12
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       72   2e-12
gi|112421108 capicua homolog [Homo sapiens]                            72   2e-12

>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 1548 bits (4009), Expect = 0.0
 Identities = 780/780 (100%), Positives = 780/780 (100%)

Query: 1   MSKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATDYGPE 60
           MSKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATDYGPE
Sbjct: 1   MSKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATDYGPE 60

Query: 61  EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST 120
           EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST
Sbjct: 61  EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST 120

Query: 121 LAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRW 180
           LAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRW
Sbjct: 121 LAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRW 180

Query: 181 TCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPES 240
           TCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPES
Sbjct: 181 TCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPES 240

Query: 241 GTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAAT 300
           GTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAAT
Sbjct: 241 GTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAAT 300

Query: 301 GPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYP 360
           GPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYP
Sbjct: 301 GPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYP 360

Query: 361 QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNAS 420
           QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNAS
Sbjct: 361 QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNAS 420

Query: 421 SVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQS 480
           SVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQS
Sbjct: 421 SVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQS 480

Query: 481 VPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQ 540
           VPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQ
Sbjct: 481 VPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQ 540

Query: 541 LSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEP 600
           LSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEP
Sbjct: 541 LSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEP 600

Query: 601 LPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTAFY 660
           LPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTAFY
Sbjct: 601 LPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTAFY 660

Query: 661 QAFHLNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELV 720
           QAFHLNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELV
Sbjct: 661 QAFHLNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELV 720

Query: 721 ERNSLLERENALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQPPQQPNVSSA 780
           ERNSLLERENALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQPPQQPNVSSA
Sbjct: 721 ERNSLLERENALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQPPQQPNVSSA 780


>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
          Length = 1073

 Score =  252 bits (644), Expect = 8e-67
 Identities = 256/808 (31%), Positives = 357/808 (44%), Gaps = 158/808 (19%)

Query: 71   TLNNVGDAETPGTVSPNLL--------LDGQLAAAAAAPANGGGVVSARSV---SGALAS 119
            T+NNV +    G+ +PN+         +      +AA  + G GV S  +V   SG    
Sbjct: 312  TVNNV-NITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNG 370

Query: 120  TLAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGR 179
            T++++A  +  P A      AG + G V++   QP T  +SRFRV+KLD  S EP+++GR
Sbjct: 371  TISSSAAVSSVPNAA-----AGMTGGSVSSQQQQP-TVNTSRFRVVKLD-SSSEPFKKGR 423

Query: 180  WTCMEYYERDS-----DSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQG 234
            WTC E+YE+++     +  ++ +  + ++ +   + T+ER+S  G++  S V  ++    
Sbjct: 424  WTCTEFYEKENAVPATEGVLINKVVETVKQNP-IEVTSERESTSGSSVSSSVSTLSHYTE 482

Query: 235  AHGP-ESGTDSSLTAVSQLPPSEKMSQP-----TPAQPQSFSVGQPQPPPPPVGGAVAQS 288
            + G  E G  + +    Q    ++  QP     T  Q    S G    P   +  +++QS
Sbjct: 483  SVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQS 542

Query: 289  SAP----------------LPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLP----PTN 328
                               L P P  AT     M+AA   QP      G T      P+ 
Sbjct: 543  QISQVQLQSQELSYQQKQGLQPVPLQAT-----MSAATGIQPSPVNVVGVTSALGQQPSI 597

Query: 329  VTLAQPAM----SLPPQPGPAVGAPAAQQPQQFAYPQP----QIPPGHLLPVQPSGQSEY 380
             +LAQP +    + PP   P  GAP  QQ  Q+   QP    Q+ PGH+  V  +  SEY
Sbjct: 598  SSLAQPQLPYSQAAPPVQTPLPGAPPPQQ-LQYGQQQPMVSTQMAPGHVKSVTQNPASEY 656

Query: 381  LQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNA------SSVGAQLMGASSQP- 433
            +QQ        S  QPSS G  A       +PV   Q        ++V AQ  GAS QP 
Sbjct: 657  VQQQPILQTAMSSGQPSSAGVGAG---TTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPV 713

Query: 434  SEAMAPRTGPAQGGQVAPC-QPTGVPPATVGGVVQPCLGPAGAGQPQS---VPPPQMG-- 487
             +A A  +    G Q+A   Q   +P A      Q        G P S   VPP Q G  
Sbjct: 714  GQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGII 773

Query: 488  ------------------GSGPLSAVPGGPHAVVPGVPNV-----PAAVPAPSVPSVSTT 524
                                  L  VP  P  V P    +     PA    PS  S+S T
Sbjct: 774  HQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVT 833

Query: 525  SVT-------MPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDL 577
            S         MP+ P  L   Q ++  TP +++ +++Q V  P    T++      Q  L
Sbjct: 834  SQVSSTGPSGMPSAPTNLVPPQNIAQ-TPATQNGNLVQSVSQPPLIATNTNLPLAQQIPL 892

Query: 578  SQFQTQTQPLV----GQVDDTRRKSEP----LPQPPLSLIAENKPVVKPPVADSLANPLQ 629
            S  Q   Q L      Q++D RR +EP    LPQ  +S  +     V    + SLA    
Sbjct: 893  SSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQT-ISGDSGGMSAVSDGSSSSLAASAS 951

Query: 630  LTPMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDNK 689
            L P+      V  +  P+   ED                       +S+SG  VVAIDNK
Sbjct: 952  LFPLK-----VLPLTTPLVDGED-----------------------ESSSGASVVAIDNK 983

Query: 690  IEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPT-- 747
            IEQAMDLVKSHLMYAVREEVEVLKEQIKEL+E+NS LE+EN LLK+L+S +QL+Q     
Sbjct: 984  IEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQL 1043

Query: 748  QQANPGSTSQQQAVIAQPPQPTQPPQQP 775
            Q  +P +T+Q Q         TQPP QP
Sbjct: 1044 QTGSPPATTQPQGT-------TQPPAQP 1064



 Score = 36.6 bits (83), Expect = 0.092
 Identities = 95/470 (20%), Positives = 145/470 (30%), Gaps = 131/470 (27%)

Query: 240 SGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPF-PGA 298
           +G  S+ T+    PP   +  P PA   + S   PQPPPP     ++Q+     P  PG 
Sbjct: 46  TGVGSNATSSEDFPPPSLLQPPPPA---ASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGG 102

Query: 299 A----------TGPQPMMAAAQPSQPQGAGPGGQTLPP--------------TNVTLAQP 334
                      T   P   +A  S         ++                  +V+L++ 
Sbjct: 103 TQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRA 162

Query: 335 AMSLPPQPGPA---------VGAPAAQQPQQFAYPQPQIP--PGHLLPVQPSGQSEYLQQ 383
                P+   +            P A  P Q   PQP +P  P   + +  +    +L  
Sbjct: 163 TDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHH 222

Query: 384 H---------VAGLQPPSPAQPSST----GAAASPATAATLPVGTGQNASSVG-AQLMGA 429
           H           G   PS    +S     G  +SP +      G+  + + V     + +
Sbjct: 223 HHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSS 282

Query: 430 SSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLG------------------ 471
           S  P+  M     P+  G +     TG   +TV  V    +G                  
Sbjct: 283 SGSPASVMTNMRAPSTTGGIGINSVTGT--STVNNVNITAVGSFNPNVTSSMLGNVNIST 340

Query: 472 ---PAGAGQPQSVPPPQMGGSGP--LSAVPGG---PHAVVPGVPNVPAAVPAPSV----- 518
              P+ AG   SV P    G     LS +  G     A V  VPN  A +   SV     
Sbjct: 341 SNIPSAAG--VSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQ 398

Query: 519 -PSVSTTSV------------------------------------------TMPNVPAPL 535
            P+V+T+                                            T+   P  +
Sbjct: 399 QPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEV 458

Query: 536 AQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQ 585
              ++ +S + VS S S + H    +  G   APT + Q    Q Q Q Q
Sbjct: 459 TSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQ 508



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 31/103 (30%), Positives = 41/103 (39%), Gaps = 10/103 (9%)

Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFP 296
           G  SG+ S+L A      S   S      P        QPPPP    A + +S P PP P
Sbjct: 32  GSGSGSASALNAAGTGVGSNATSSEDFPPPSLL-----QPPPP----AASSTSGPQPPPP 82

Query: 297 GAATGPQPMMAAAQPSQPQGAGPGGQT-LPPTNVTLAQPAMSL 338
            +          AQP  P G     ++    T+VT AQ + S+
Sbjct: 83  QSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISASI 125


>gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens]
          Length = 144

 Score =  120 bits (302), Expect = 4e-27
 Identities = 70/113 (61%), Positives = 82/113 (72%), Gaps = 9/113 (7%)

Query: 665 LNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNS 724
           L T   S  L +S+SG  VVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKEL+E+NS
Sbjct: 30  LGTENASVRLDNSSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNS 89

Query: 725 LLERENALLKSLSSNDQLSQLPT--QQANPGSTSQQQAVIAQPPQPTQPPQQP 775
            LE+EN LLK+L+S +QL+Q     Q  +P +T+Q Q         TQPP QP
Sbjct: 90  QLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGT-------TQPPAQP 135


>gi|13569901 TSC22 domain family, member 4 [Homo sapiens]
          Length = 395

 Score =  117 bits (292), Expect = 5e-26
 Identities = 109/362 (30%), Positives = 154/362 (42%), Gaps = 64/362 (17%)

Query: 443 PAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAV--PGG-- 498
           P       P  PTG PP    G  +P   P G G P++  PP    S     V  P G  
Sbjct: 25  PGASDPPTPQPPTGPPPRLPNG--EPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLG 82

Query: 499 -------------------PHA---VVPGVPNVPAAVPAPSVPS---VSTTSVTMPNVPA 533
                              PH+   ++ G+          S+ S   +++  +  P  P+
Sbjct: 83  EPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPS 142

Query: 534 PLAQSQ----QLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVG 589
            L+Q      +    +P  ++ S    +G  + P    A    P S  S  Q   +P  G
Sbjct: 143 GLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKP-PLSASSPQQRPPEPETG 201

Query: 590 QVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDG 649
           +   T R + PLP   +   A       PP++   A  ++L  M   A        P+D 
Sbjct: 202 ESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLR-MELGAPEEMGQVPPLDS 260

Query: 650 DEDRNPSTAFYQAFHLNTLKESKSLW------------------------DSASGGGVVA 685
              R  S A Y     + + +S   +                        D +  G +V 
Sbjct: 261 ---RPSSPALYFTHDASLVHKSPDPFGAVAAQKFSLAHSMLAISGHLDSDDDSGSGSLVG 317

Query: 686 IDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQL 745
           IDNKIEQAMDLVKSHLM+AVREEVEVLKEQI+EL ERN+ LE+EN LL++L+S +QL+QL
Sbjct: 318 IDNKIEQAMDLVKSHLMFAVREEVEVLKEQIRELAERNAALEQENGLLRALASPEQLAQL 377

Query: 746 PT 747
           P+
Sbjct: 378 PS 379



 Score = 83.6 bits (205), Expect = 7e-16
 Identities = 94/327 (28%), Positives = 130/327 (39%), Gaps = 41/327 (12%)

Query: 125 ATSAPAPGAPGGP--QLAGSSAGPVTAAP------SQPPTTCSSRFRVIKLDHGSGEPYR 176
           A+  P P  P GP  +L      P           S PP   SSRFRV+KL HG GEPYR
Sbjct: 27  ASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPYR 86

Query: 177 RGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASM-QGA 235
           RGRWTC++ YERD +        + IR +S          G G       + +AS+  GA
Sbjct: 87  RGRWTCVDVYERDLEPHSFGGLLEGIRGAS---------GGAGGRSLDSRLELASLGLGA 137

Query: 236 HGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPF 295
             P SG     T+  + PP    + P P Q +SF+ G        +G  V  S A     
Sbjct: 138 PTPPSGLSQGPTSWLRPPP----TSPGP-QARSFTGG--------LGQLVVPSKAKAEKP 184

Query: 296 PGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQ 355
           P +A+ PQ      +  +  G       LP   V            P     A   +   
Sbjct: 185 PLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRM 244

Query: 356 QFAYPQP--QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPV 413
           +   P+   Q+PP   L  +PS  + Y   H A L   SP  P    AA   + A ++  
Sbjct: 245 ELGAPEEMGQVPP---LDSRPSSPALYF-THDASLVHKSP-DPFGAVAAQKFSLAHSMLA 299

Query: 414 GTG---QNASSVGAQLMGASSQPSEAM 437
            +G    +  S    L+G  ++  +AM
Sbjct: 300 ISGHLDSDDDSGSGSLVGIDNKIEQAM 326


>gi|37622901 TSC22 domain family, member 3 isoform 2 [Homo sapiens]
          Length = 134

 Score =  108 bits (271), Expect = 1e-23
 Identities = 63/111 (56%), Positives = 76/111 (68%), Gaps = 14/111 (12%)

Query: 671 SKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLEREN 730
           S  L +SASG  VVAIDNKIEQAMDLVK+HLMYAVREEVE+LKEQI+ELVE+NS LEREN
Sbjct: 35  SVKLDNSASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLEREN 94

Query: 731 ALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQP--PQQPNVSS 779
            LLK+L+S +QL +             Q  +  + P P  P  P+ P  S+
Sbjct: 95  TLLKTLASPEQLEKF------------QSCLSPEEPAPESPQVPEAPGGSA 133


>gi|37622903 TSC22 domain family, member 3 isoform 1 [Homo sapiens]
          Length = 200

 Score =  107 bits (268), Expect = 3e-23
 Identities = 61/105 (58%), Positives = 73/105 (69%), Gaps = 14/105 (13%)

Query: 677 SASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSL 736
           SASG  VVAIDNKIEQAMDLVK+HLMYAVREEVE+LKEQI+ELVE+NS LEREN LLK+L
Sbjct: 107 SASGASVVAIDNKIEQAMDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTL 166

Query: 737 SSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQP--PQQPNVSS 779
           +S +QL +             Q  +  + P P  P  P+ P  S+
Sbjct: 167 ASPEQLEKF------------QSCLSPEEPAPESPQVPEAPGGSA 199


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  101 bits (251), Expect = 3e-21
 Identities = 120/411 (29%), Positives = 146/411 (35%), Gaps = 48/411 (11%)

Query: 237  GPESGTDSSLTAVSQLPPSEKMSQPTPAQ---PQSFSV-GQPQPP---PPPVGGAVAQSS 289
            GP +       A+S    S K ++ TPA    P S S  G P PP   PP   G  A  S
Sbjct: 899  GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS 958

Query: 290  APLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAP 349
                P P AAT P P    A PS      P   T P      A P+    P P PAV  P
Sbjct: 959  PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP-PAVTPP 1017

Query: 350  AAQ-QPQQFAYPQPQIPPGHLLPVQPSGQSEYL-------QQHVAGLQPP--SPAQPSST 399
            + +  P    +P+    P    P  P G                A L  P   PA PS  
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK 1077

Query: 400  GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPP 459
            GA   PA     P G     S  GA +  A++ PS      T P +G   AP  P   PP
Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG---APTTPAATPP 1134

Query: 460  ATVGGVVQPCLGPAGA-GQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSV 518
            +  GG+  P   P GA   P + PP   GG   L+  P        G P  PAA P    
Sbjct: 1135 SPKGGLATP--PPKGAPTTPAATPPSPKGG---LATPP------PKGAPTTPAATPPSPK 1183

Query: 519  PSVSTTSVT-MPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDL 577
              ++T S    P  PA    S +    TP  +            AP T +A    P+  L
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKG-----------APTTPAATPPSPKGGL 1232

Query: 578  SQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPP-VADSLANP 627
            +    +  P          K  P   PP    A   P   PP +   LA P
Sbjct: 1233 ATPSPKGAPTTPAATPPSPKGGPATPPPKG--APTPPAATPPSLKGGLATP 1281



 Score = 96.7 bits (239), Expect = 7e-20
 Identities = 116/417 (27%), Positives = 149/417 (35%), Gaps = 67/417 (16%)

Query: 231  SMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSA 290
            S++GA  P + T          PPS K    TP+ P+   +     PP P GG       
Sbjct: 1075 SLKGAPTPPAAT----------PPSPKGGPATPS-PKGAPMPPAATPPSPKGGLAT---- 1119

Query: 291  PLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPA 350
              PP  GA T P     AA P  P+G    G   PP       PA + PP P   +  P 
Sbjct: 1120 --PPHKGAPTTP-----AATPPSPKG----GLATPPPKGAPTTPAAT-PPSPKGGLATPP 1167

Query: 351  AQQPQQFAYPQPQIPPGHLLPVQPSGQ----SEYLQQHVAGLQPPSPAQPSSTGAAASPA 406
             +         P  P G L    P G     +        GL  PSP      GA  +PA
Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-----KGAPTTPA 1222

Query: 407  TAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVV 466
                 P G     S  GA    A++ PS    P T P +G   AP  P   PP+  GG+ 
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG---APTPPAATPPSLKGGLA 1279

Query: 467  QPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGG---PHAVVP----GVPNVPAAVPAPSVP 519
             P     GA  P  V PP   G GP ++ P G   P A  P    G P  P    AP+ P
Sbjct: 1280 TP--PHKGAPNPAVVTPPSPKG-GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336

Query: 520  SVSTTSVT-MPNVPAPLAQSQQLSSHTPVSRS-----SSIIQHVG-----------LPLA 562
            +V+  S    P +PA    S+     TP S+      ++   H G            P  
Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKG-GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI 1395

Query: 563  PGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPP 619
            P     PTS     LS  +    P+  +   T  K +  P     +  +  P    P
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP 1452



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 164/673 (24%), Positives = 232/673 (34%), Gaps = 118/673 (17%)

Query: 78   AETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAP------ 131
            A TP   +P  L  G LA      A    VV+  S  G  A++    A + PA       
Sbjct: 1263 APTPPAATPPSLKGG-LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK 1321

Query: 132  GAPGGPQLAGSSAGPVTAAPSQ------PPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEY 185
            G+PG P   G+   P    PS       P TT SS+        G   P  +   T    
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK-------GGPTTPSSKEGPTPPAA 1374

Query: 186  YERDSDSSVLT----RSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESG 241
                     +T    + G  I  S   D T+     L         V  + +GA  P  G
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAI-PSPKGDPTSPAVIPLSPKKAPATPV--TREGAATPSKG 1431

Query: 242  --TDSSLTAVS-QLPPSEKMSQPTPAQPQSF------SVGQPQPPPPPVGGAVAQSSAPL 292
              T  ++T VS +  P+    +  PA P S       +V  P P  PP    VA SS+P 
Sbjct: 1432 DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491

Query: 293  PPFPGAATGPQPMMAAAQPSQPQ--GAGPGGQTLP--PTNVTLAQ--------------P 334
                  A    P + A  PS P+   A P  +  P  PT   L++              P
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551

Query: 335  AMSLP-PQPGPAV----GAPAAQQPQQFAYPQPQIPPGH---------LLPVQPSGQSEY 380
            AM++P P+  PA+     APA    ++ + P    P  +         L+P   +  S  
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611

Query: 381  LQQHVAGLQPPS----PAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEA 436
                   + PPS    PA P+  G   SP    +    +  + +SV  ++     Q S+ 
Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671

Query: 437  MAPRTGPAQGGQ--VAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPP--QMGGSGPL 492
            +  + GP    +  VAP  P   P  T      P    + A  P   P P  + G  GPL
Sbjct: 1672 LPAKKGPTALKEVLVAPA-PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPL 1730

Query: 493  SAVPGGPHAVV-------------PGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQ 539
            S V   P   V                P  P A P     +  T +     +P P + S 
Sbjct: 1731 STVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASV 1790

Query: 540  QLSSHTPVSRSSSIIQHVGLPLAPGTHSAPT------SLPQSDLSQFQTQTQPLVGQVDD 593
              +   PVS          LPLAP     PT       LP S     ++ ++PL    +D
Sbjct: 1791 SAAPSPPVS----------LPLAPS--PVPTLPPKQQFLPSSPGLVLESPSKPLAPADED 1838

Query: 594  TRRKSEPLPQP-----PLSLIAENKPVVK----PPVADSLANPLQLTPMNSLATSVFSIA 644
                  P P+P     P   +  N P  K    P    S   P+      S   S    +
Sbjct: 1839 ELLPLIP-PEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDES 1897

Query: 645  IPVDGDEDRNPST 657
            +P   ++D   +T
Sbjct: 1898 VPELEEQDSTQAT 1910



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 87/359 (24%), Positives = 124/359 (34%), Gaps = 31/359 (8%)

Query: 254  PSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQ 313
            PS K +   PA   S   G P P    +  AV   S    P P A T P P    A P  
Sbjct: 1574 PSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP-- 1631

Query: 314  PQGAGPGGQTLPPTNVTLAQPAMSLPPQ---------PGPAVGAPAAQQP----QQFAYP 360
               A  G  T PP   +  + + + P           P  + G PA + P    +    P
Sbjct: 1632 ---APKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688

Query: 361  QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNAS 420
             P+  P    P +   Q++        + P   A+  S G  ++ A A  LPV   Q  S
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPV---QKDS 1745

Query: 421  SVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVP---PATVGGVVQPCLGPAGAGQ 477
            S  A+   AS  P   +AP    A     A      +P    A+V     P +    A  
Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805

Query: 478  PQSVPPPQM----GGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPA 533
            P    PP+        G +   P  P A       +P   P P    V   SV + N+P 
Sbjct: 1806 PVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSV-LVNMPT 1864

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVD 592
            P  +S  +   TP ++      + G      +  +   L + D +Q  TQ   L    +
Sbjct: 1865 P--KSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAE 1921



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 100/485 (20%), Positives = 158/485 (32%), Gaps = 79/485 (16%)

Query: 249 VSQLPPSEKMSQP---------TPAQPQSFSVGQPQPPPP---PVGGAVAQSSAPLPPFP 296
           V+Q+P S   + P           A   +F V     PP    P+      S A L   P
Sbjct: 428 VAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAP 487

Query: 297 GAATGPQPMMAAAQ--PSQPQGAGPGGQTLPPTNVTLAQPAMS-LPPQPGPAVGAPAAQQ 353
            A   P   +A     P  P    P      P++V +  P    L   P    GAP +  
Sbjct: 488 VAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFS-- 545

Query: 354 PQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAAS--------- 404
           P Q      + P   +LP+  +              P  P  P +T A  S         
Sbjct: 546 PAQAGLTTKKDPT--VLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGK 603

Query: 405 PATAATLPVGTGQNASSVGAQLMGA--SSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATV 462
           PA++ T P+G   +AS +         S+ P    +  T       +    P GV P T 
Sbjct: 604 PASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTA 663

Query: 463 GGV----------------VQPCLGPAGAGQPQSVP-PPQMGGSGPLSAVPGG---PHAV 502
            G                 + P   P   G   ++P  P    + P++  P     P A 
Sbjct: 664 KGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLAT 723

Query: 503 VPGVPNVPAAVPAPSVP------------SVSTTSVTMPNVPAPLAQSQQLSSHTPVSRS 550
           +   P +P +VP+PS+P             +S TS   P   +P     + S  +  + S
Sbjct: 724 LVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS 783

Query: 551 SSIIQH-------VGLPLAPGTHSAPTSL----PQSDLSQFQTQTQPLVGQ-VDDTRRKS 598
              + +       +G+ ++P T   PT      P + +    +   P+    + +     
Sbjct: 784 KGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF 843

Query: 599 EPLPQPPLSLIAENKPVVKPPVADSLANPLQ-----LTPMNSLATSVFSIAIPVDGDEDR 653
           +     P +  +   P  K     S   PL      L P  +   SV ++  P +G    
Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903

Query: 654 NPSTA 658
            P  A
Sbjct: 904 APKQA 908



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 93/424 (21%), Positives = 147/424 (34%), Gaps = 85/424 (20%)

Query: 265 QPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTL 324
           QPQ+ +   P      V  A+ Q    LPP    A    P+ AA Q S            
Sbjct: 18  QPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASP----------- 66

Query: 325 PPTNVTLAQPAMSLP-PQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQ 383
            P+  T+A   + +P PQ       P    P+   +    I P    P+ P+        
Sbjct: 67  FPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGP----PISPAA------- 115

Query: 384 HVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGP 443
            +A   P        T ++++P     L   + Q +S+    L+  +S PS A+A     
Sbjct: 116 -LALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLL--TSPPSVAVAESGSV 172

Query: 444 -AQGGQVAPCQP-----------------TGVPPATVGGVVQPCLGPAG------AGQPQ 479
                 +AP +P                 T  PP  V  V   C+ P        A  PQ
Sbjct: 173 ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQ 232

Query: 480 SVPPPQMGGSGP------LSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPA 533
           + P   +  + P      +S+V   P    PG  ++   V  P+  S+ST S     +P 
Sbjct: 233 TTPTTTLAIASPQVKDTTISSVLISPQN--PGSLSLKGPVSPPAALSLSTQS-----LPV 285

Query: 534 PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDD 593
             +  +    +TP             P++ G+H AP  L QS     Q   Q     + D
Sbjct: 286 VTSSQKTAGPNTPPD----------FPISLGSHLAP--LHQSSFGSVQLLGQTGPSALSD 333

Query: 594 TRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDR 653
              K+  +          ++  V PP    L +  ++ P    A  V + ++      D+
Sbjct: 334 PTVKTISVDHSSTGASYPSQRSVIPP----LPSRNEVVPATVAAFPVVAPSV------DK 383

Query: 654 NPST 657
            PST
Sbjct: 384 GPST 387


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 93.6 bits (231), Expect = 6e-19
 Identities = 125/501 (24%), Positives = 166/501 (33%), Gaps = 47/501 (9%)

Query: 107 VVSARSVSGALASTLAAAA---TSAPAPGAPGGP-----QLAGSSAGPVTAAPS---QPP 155
           V   ++      S L+A A   TS P PG P        + AG+  G    APS   +PP
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201

Query: 156 TTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERD 215
           T    +      +H + EP    R        R S    L R       SS    ++   
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAAR-------RRPSAGGGLQRPASRSLSSSATPLSSPAR 254

Query: 216 SGLGATGGSVVVVVASMQGAHG-----PESGTDSSLTAVSQLPP--SEKMSQPTPAQPQS 268
           SG  A G        S     G     P   T     A   L P  S  ++ P+P+    
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ 314

Query: 269 FSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQ-----PMMAAAQPSQPQGAGPGGQT 323
                  P  P       Q + PLP  P + + P      P   A  PSQ      G  T
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT-TSLGSPT 373

Query: 324 LPPTNVTLAQPAMSL----PPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSE 379
           L  T+  L  P +S     PPQ  PA+  P  Q P       P  P     P  P+  + 
Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433

Query: 380 YLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAP 439
           +L Q      P  P Q   +  A+ P + +  P      + +     +  S   S  M+P
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493

Query: 440 RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGP 499
              P          P   PP      +Q    P  A    + PP Q   S P S     P
Sbjct: 494 SATP----------PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543

Query: 500 HAVVPGVPNVPAAVPAPSVPSVSTTSVTM--PNVPAPLAQSQQLSSHTPVSRSSSIIQHV 557
            +    +P  P A P P  P V    +    P+ PA           TP   +S     +
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603

Query: 558 GLPLAPGTHSAPTSLPQSDLS 578
            L LAPG    P+  P S LS
Sbjct: 604 TLALAPGPPPPPSRSPSSTLS 624



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 146/568 (25%), Positives = 193/568 (33%), Gaps = 83/568 (14%)

Query: 96  AAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPG----GPQLAGSSAGPVTAAP 151
           A  A    G  +  +   +G   S   ++   A  P A G     P    +S GPV++  
Sbjct: 59  AERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118

Query: 152 SQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQT 211
               TT         L   + E   RG+ T  E  +R                 S     
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKAT--EAPKR-----------------SALSAG 159

Query: 212 AERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSV 271
           A RD+  G T G+    +A    A G E G      +    PP+E   + + +     S 
Sbjct: 160 ARRDTS-GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG-PRKSVSSASEHST 217

Query: 272 GQPQPPP---PPVGGAVAQ------SSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGG- 321
            +P P     P  GG + +      SS+  P    A +GP        P+ P    P G 
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277

Query: 322 QTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYL 381
           Q L P  VT   P     P  GP   +P A  P   A  Q Q PP   LP  P   S   
Sbjct: 278 QALRPPQVT--PPRKDAAPALGPLSSSPLAT-PSPSAALQSQAPP--TLPATPHSSSLTC 332

Query: 382 QQHVA-GLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQ--PSEAMA 438
           Q      L PPSP+ P S     SP   AT P    Q  +S+G+  + A+    PS  ++
Sbjct: 333 QLATPLPLAPPSPSAPPSLQTLPSPP--ATPP---SQATTSLGSPTLQATHSFLPSPPLS 387

Query: 439 P-RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSV-------------PPP 484
           P  T P Q        P   PP+       P L P     PQ+              PPP
Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPAS---PPLSPLATPSPQAPNALAVHLLQAPFSPPP 444

Query: 485 QMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544
                 P S          P  P V  +   PS    S  +  +   P+P A      S 
Sbjct: 445 SPPVQAPFSP---------PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 495

Query: 545 TPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQP 604
           TP  ++   +    L LA     AP +L    L    +      GQ   +   S  LP  
Sbjct: 496 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--PSASLPMS 553

Query: 605 PLSLIAENKPVVKPPVADSLANPLQLTP 632
           PL+      P   PPV   LA PL   P
Sbjct: 554 PLA----TPPPQAPPV---LAAPLLQVP 574



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 109/438 (24%), Positives = 159/438 (36%), Gaps = 65/438 (14%)

Query: 248 AVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMA 307
           A ++ P +      TP  P     G P+PPPP    A+    A        A G +P+  
Sbjct: 12  AAARTPAARAPGLLTPRPP-----GSPRPPPPVTPAALRVLGA------AGAVGRKPLAE 60

Query: 308 AAQPSQPQGAGPGGQTLP-------PTNV--TLAQPAMSLPPQPGPAVGAPAAQQPQQFA 358
            A        G GG T+P       PT    T ++   S PP  G    AP A+      
Sbjct: 61  RA-------GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTS--- 110

Query: 359 YPQPQIPPGHLL------PVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLP 412
            P P   PG         P+   G     ++ VA  +     + S+  A A   T+   P
Sbjct: 111 -PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP 169

Query: 413 VGTGQNASSVGAQLMGAS---SQPSEAMAPR---TGPAQGGQVAPCQPTGVP-------P 459
            GT   A +  ++  G      +P+ +  PR    GP +    A    T  P       P
Sbjct: 170 -GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 228

Query: 460 ATVGGVVQPCLGPAGAGQPQSVPPPQMGGSG---------PLSAVPGGPHAVVPGVPNVP 510
           +  GG+ +P      +       P + G S          P    P G  A+ P     P
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288

Query: 511 AAVPAPSVPSVSTTSVTMPNVPAPL-AQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAP 569
               AP++  +S++ +  P+  A L +Q+      TP S S +      LPLAP + SAP
Sbjct: 289 RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP 348

Query: 570 TSLPQSDLSQFQTQTQPLVGQVDDTRRKSEP-LPQPPLSLIAENKPVVKPPVADSLANPL 628
            SL           +Q        T + +   LP PPLS +A   P   P +A     PL
Sbjct: 349 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA---LPPL 405

Query: 629 QLTPMNSLATSVFSIAIP 646
           Q  P    +  +  +A P
Sbjct: 406 QAPPSPPASPPLSPLATP 423



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 84/287 (29%), Positives = 104/287 (36%), Gaps = 46/287 (16%)

Query: 238 PESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPG 297
           P S    SL A    PP +    P  + P S S   P   PPP+     Q + P P  P 
Sbjct: 466 PPSQAPPSLAA----PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521

Query: 298 AATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQF 357
           A   P P+ A   PS P  + PG     P+      P  + PPQ  P + AP  Q P   
Sbjct: 522 ALATP-PLQAL--PS-PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP--- 574

Query: 358 AYPQPQIPPGHLLPVQP-------SGQSEYLQQHVAGLQPPSPAQ-PSSTGAAASPATAA 409
             P P   P    P +P       S     L   +A   PP P++ PSST +    A   
Sbjct: 575 --PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA--- 629

Query: 410 TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPC 469
               G   +A+S   +L G  S P    A    P    ++A C P     A   G   P 
Sbjct: 630 ----GHSSSATSTPEELRGYDSGPEGGAA--ASPPPDAELAACHPA----AWSRGPAPPL 679

Query: 470 LGPAGAGQPQSVPPPQMGGS-----------GPLSAVPGGPHAVVPG 505
                 G P   PP    GS           GP SA P  P A+ PG
Sbjct: 680 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP-APGALDPG 725



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 72/279 (25%), Positives = 91/279 (32%), Gaps = 64/279 (22%)

Query: 81  PGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLA 140
           P   +P  L    L A  + PA+  G       +    S LA     AP   A    Q+ 
Sbjct: 515 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 574

Query: 141 GSS-AGPVTAAPSQPPT-----TCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSV 194
            S  A P   AP +PPT     + S     + L  G   P  R            S SS 
Sbjct: 575 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR------------SPSST 622

Query: 195 LTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPP 254
           L+   D   HSS+   T E   G  +                GPE G      A +  PP
Sbjct: 623 LS-GPDLAGHSSSATSTPEELRGYDS----------------GPEGG------AAASPPP 659

Query: 255 SEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPP--FPGAATGPQPMMAAAQPS 312
             +++   PA                     A S  P PP  F GA   P P   A  P 
Sbjct: 660 DAELAACHPA---------------------AWSRGPAPPLAFRGAPGAPLPWPPATGPG 698

Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAA 351
              G     +T  P + T A  A+   P PG + G  AA
Sbjct: 699 SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 737



 Score = 33.5 bits (75), Expect = 0.78
 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 98  AAAPANGGGVVSARSVSGALASTLAAAATS-APAPGAPGGPQLAGSSAGPVTAAPSQ 153
           A  P +  G+ +     G  ++T A  A    P+PG  GG   AG+ AG  + +P Q
Sbjct: 694 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 750


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 127/491 (25%), Positives = 165/491 (33%), Gaps = 57/491 (11%)

Query: 107 VVSARSVSGALASTLAAAA---TSAPAPGAPGGP-----QLAGSSAGPVTAAPS---QPP 155
           V   ++      S L+A A   TS P PG P        + AG+  G    APS   +PP
Sbjct: 133 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192

Query: 156 TTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERD 215
           T    +      +H + EP    R        R S    L R       SS    ++   
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAAR-------RRPSAGGGLQRPASRSLSSSATPLSSPAR 245

Query: 216 SGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVS--QLPPSEKMSQPTPAQPQSFSVGQ 273
           SG  A G            AH P       L A+   Q+ P  K + P      S  +  
Sbjct: 246 SGPSARG-------TPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297

Query: 274 PQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQ 333
           P P  PP        SAP    P   T P P   A  PSQ      G  TL  T+  L  
Sbjct: 298 PSPSAPP------SPSAP----PSLQTLPSP--PATPPSQAT-TSLGSPTLQATHSFLPS 344

Query: 334 PAMSL----PPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQ 389
           P +S     PPQ  PA+  P  Q P       P  P     P  P+  + +L Q      
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404

Query: 390 PPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQV 449
           P  P Q   +  A+ P + +  P      + +     +  S   S  M+P   P      
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP------ 458

Query: 450 APCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNV 509
               P   PP      +Q    P  A    + PP Q   S P S     P +    +P  
Sbjct: 459 ----PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 514

Query: 510 PAAVPAPSVPSVSTTSVTM--PNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHS 567
           P A P P  P V    +    P+ PA           TP   +S     + L LAPG   
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574

Query: 568 APTSLPQSDLS 578
            P+  P S LS
Sbjct: 575 PPSRSPSSTLS 585



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 144/574 (25%), Positives = 190/574 (33%), Gaps = 86/574 (14%)

Query: 76  GDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAA----TSAPAP 131
           G    P  V+P  L   ++  AA A         A  + GA     A  A    TS P  
Sbjct: 31  GSPRPPPPVTPAAL---RVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPA 87

Query: 132 GAPG--GPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERD 189
              G   P    +S GPV++      TT         L   + E   RG+ T  E  +R 
Sbjct: 88  SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT--EAPKR- 144

Query: 190 SDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAV 249
                           S     A RD+  G T G+    +A    A G E G      + 
Sbjct: 145 ----------------SALSAGARRDTS-GPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 187

Query: 250 SQLPPSEKMSQPTPAQPQSFSVGQPQPPP---PPVGGAVAQ------SSAPLPPFPGAAT 300
              PP+E   + + +     S  +P P     P  GG + +      SS+  P    A +
Sbjct: 188 RPRPPTEG-PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246

Query: 301 GPQPMMAAAQPSQPQGAGPGG-QTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAY 359
           GP        P+ P    P G Q L P  VT   P     P  GP   +P A  P   A 
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVT--PPRKDAAPALGPLSSSPLAT-PSPSAP 303

Query: 360 PQPQIPPG-HLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQN 418
           P P  PP    LP  P+              PPS A  +S G+    AT + LP      
Sbjct: 304 PSPSAPPSLQTLPSPPA-------------TPPSQAT-TSLGSPTLQATHSFLPSPPLSP 349

Query: 419 ASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQP 478
            ++   Q     + P+ A+ P   P       P  P   P       +   L  A    P
Sbjct: 350 LATPPPQ-----APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404

Query: 479 QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQS 538
            S PP Q   S P S             P V  +   PS    S  +  +   P+P A  
Sbjct: 405 PS-PPVQAPFSPPAS-------------PPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 450

Query: 539 QQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKS 598
               S TP  ++   +    L LA     AP +L    L    +      GQ   +   S
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--PS 508

Query: 599 EPLPQPPLSLIAENKPVVKPPVADSLANPLQLTP 632
             LP  PL+      P   PPV   LA PL   P
Sbjct: 509 ASLPMSPLA----TPPPQAPPV---LAAPLLQVP 535



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 84/287 (29%), Positives = 104/287 (36%), Gaps = 46/287 (16%)

Query: 238 PESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPG 297
           P S    SL A    PP +    P  + P S S   P   PPP+     Q + P P  P 
Sbjct: 427 PPSQAPPSLAA----PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482

Query: 298 AATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQF 357
           A   P P+ A   PS P  + PG     P+      P  + PPQ  P + AP  Q P   
Sbjct: 483 ALATP-PLQAL--PS-PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP--- 535

Query: 358 AYPQPQIPPGHLLPVQP-------SGQSEYLQQHVAGLQPPSPAQ-PSSTGAAASPATAA 409
             P P   P    P +P       S     L   +A   PP P++ PSST +    A   
Sbjct: 536 --PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA--- 590

Query: 410 TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPC 469
               G   +A+S   +L G  S P    A    P    ++A C P     A   G   P 
Sbjct: 591 ----GHSSSATSTPEELRGYDSGPEGGAA--ASPPPDAELAACHPA----AWSRGPAPPL 640

Query: 470 LGPAGAGQPQSVPPPQMGGS-----------GPLSAVPGGPHAVVPG 505
                 G P   PP    GS           GP SA P  P A+ PG
Sbjct: 641 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP-APGALDPG 686



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 72/279 (25%), Positives = 91/279 (32%), Gaps = 64/279 (22%)

Query: 81  PGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLA 140
           P   +P  L    L A  + PA+  G       +    S LA     AP   A    Q+ 
Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535

Query: 141 GSS-AGPVTAAPSQPPT-----TCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSV 194
            S  A P   AP +PPT     + S     + L  G   P  R            S SS 
Sbjct: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR------------SPSST 583

Query: 195 LTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPP 254
           L+   D   HSS+   T E   G  +                GPE G      A +  PP
Sbjct: 584 LS-GPDLAGHSSSATSTPEELRGYDS----------------GPEGG------AAASPPP 620

Query: 255 SEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPP--FPGAATGPQPMMAAAQPS 312
             +++   PA                     A S  P PP  F GA   P P   A  P 
Sbjct: 621 DAELAACHPA---------------------AWSRGPAPPLAFRGAPGAPLPWPPATGPG 659

Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAA 351
              G     +T  P + T A  A+   P PG + G  AA
Sbjct: 660 SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 698



 Score = 33.5 bits (75), Expect = 0.78
 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 98  AAAPANGGGVVSARSVSGALASTLAAAATS-APAPGAPGGPQLAGSSAGPVTAAPSQ 153
           A  P +  G+ +     G  ++T A  A    P+PG  GG   AG+ AG  + +P Q
Sbjct: 655 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 711


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 151/596 (25%), Positives = 201/596 (33%), Gaps = 110/596 (18%)

Query: 107 VVSARSVSGALASTLAAAA---TSAPAPGAPGGP-----QLAGSSAGPVTAAPS---QPP 155
           V   ++      S L+A A   TS P PG P        + AG+  G    APS   +PP
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201

Query: 156 TTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERD 215
           T    +      +H + EP    R        R S    L R       SS    ++   
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAAR-------RRPSAGGGLQRPASRSLSSSATPLSSPAR 254

Query: 216 SGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVS--QLPPSEKMSQPTPAQPQSFSVGQ 273
           SG  A G            AH P       L A+   Q+ P  K + P      S  +  
Sbjct: 255 SGPSARG-------TPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306

Query: 274 PQP------PPPPVGGAVAQSSAPLPPFPGAATGPQPMMA----------------AAQP 311
           P P      P PP   A     A LPP P  AT P P+                  A  P
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLAT-PLPLAPPSPSAPPSLQTLPSPPATPP 365

Query: 312 SQ--------PQGAGPGGQTLPPTNV--TLAQPAMSLPPQP--------GPAVGAPAAQQ 353
           SQ        P  A P  QT+PP  V  +L  P++  PP P          ++G+P  Q 
Sbjct: 366 SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA 425

Query: 354 PQQFAYPQPQIPPGHLL----PVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAA 409
              F    P+     L     P      S  LQ  ++   P SP   +S   A SP  ++
Sbjct: 426 THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS--LPASPPLQTSLSPAVSP-LSS 482

Query: 410 TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPT-GVPPATVGGVVQP 468
            L +   Q  SS+      AS  P   ++    P    Q +   P+   PPA++      
Sbjct: 483 PLTIHPLQALSSL------ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL------ 530

Query: 469 CLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTM 528
              P     P   PPP    S PL+     PH   P  P  P  + AP  P  +    T 
Sbjct: 531 -TTPPLENLPSLAPPPLQTASAPLTT----PHLETPPCP-APCPLQAPPSPLTTPPPETP 584

Query: 529 PNVPAPLAQSQQLSSHTPVSRSSS------------IIQHVGLPLAPGTHSAPTSLPQSD 576
            ++  P  Q+    +  P+    S                + LP      S P S P S 
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644

Query: 577 LSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTP 632
           L+    Q  P    V   +    P P PP+   A   P   PPV+ S   P Q  P
Sbjct: 645 LATPSPQA-PNALAVHLLQAPFSPPPSPPVQ--APFSPPASPPVSPSATPPSQAPP 697



 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 111/418 (26%), Positives = 148/418 (35%), Gaps = 87/418 (20%)

Query: 231 SMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPP--------PPPVG 282
           S   +H P++   S +     +PP E  S   P   Q+       PP        PPP+ 
Sbjct: 493 SSLASHSPQAPLSSLI-----MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ 547

Query: 283 GAVAQSSAP--------------LPPFPGAATGPQ-PMMAAAQPSQ--PQGAGPGGQTLP 325
            A A  + P               PP P     P+ P   A  P Q  P  A P  Q LP
Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607

Query: 326 PTNVTLAQPAMSLPPQPGPAVGAPAAQQP---------QQFAYPQPQIPPG---HLL--P 371
              ++   P  + PPQ  P +  P  Q P            A P PQ P     HLL  P
Sbjct: 608 SPPLS---PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664

Query: 372 VQPSGQSEYLQQHVAGLQPPS--PAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGA 429
             P   S  +Q   A   PP+  P  PS+T  + +P + A  P+    +  +    +  +
Sbjct: 665 FSPP-PSPPVQ---APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA-SPPMSPS 719

Query: 430 SSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPP------ 483
           ++ P +A  P   P    QV P  P   PP +      P + P  A  P  VPP      
Sbjct: 720 ATPPPQAPPPLAAPPL--QVPPSPPAS-PPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776

Query: 484 ------------PQMGGSGPLSAVPGGPHAVVPG---------VPNVPAAVPAPSVPSVS 522
                       P    + PL A+P  P A  PG         +P  P A P P  P V 
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALP-SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835

Query: 523 TTSVTM--PNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLS 578
              +    P+ PA           TP   +S     + L LAPG    P+  P S LS
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 893



 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 116/474 (24%), Positives = 166/474 (35%), Gaps = 68/474 (14%)

Query: 212 AERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSV 271
           AER  G+G        +  S   A    S   SS    S+ P S +  +  PA+  + S 
Sbjct: 59  AERAGGIGGA-----TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK--NTSP 111

Query: 272 GQPQPP--------PPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQT 323
           G    P        P P+G    + SA      G AT      A +  ++   +GP   T
Sbjct: 112 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171

Query: 324 LPP----------TNVTLAQPAMSLPPQP---GPAVGAPAAQQ-----PQQFAYPQPQIP 365
             P          T V L +PA S  P+P   GP     +A +     P   A  +P   
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231

Query: 366 PGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQ 425
            G   P   S     L      L  P+ + PS+ G   +PA  +            + A 
Sbjct: 232 GGLQRPASRS-----LSSSATPLSSPARSGPSARGTPRAPAHPSQ------PKPKGLQAL 280

Query: 426 LMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQP-QSVPPP 484
                + P +  AP  GP     +A   P+G          +P   P  A  P  +  PP
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK-------ARPVPPPDNAATPLPATLPP 333

Query: 485 QMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544
               + PL   P  P A  P +  +P+  P  + PS +  S+T P + AP +        
Sbjct: 334 SPPLATPLPLAPPSPSAP-PSLQTLPS--PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390

Query: 545 TPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQP 604
            P S +S  +Q    PLA  +  A TSL    L            Q   +     P  Q 
Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL------------QATHSFLTMSPR-QT 437

Query: 605 PLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTA 658
             SL + ++P   PP +  L  PL L     L TS+     P+      +P  A
Sbjct: 438 QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA 491



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 82/315 (26%), Positives = 108/315 (34%), Gaps = 66/315 (20%)

Query: 253 PPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPS 312
           P S   + P+ A P   +     PP PP    ++ S+ P P  P     P   +  + P+
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743

Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQ------------------------------- 341
            P    P     P     LA P + +PP                                
Sbjct: 744 SPP-MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802

Query: 342 -----PGPAVGAPAAQQPQQ-FAYPQPQIPP---GHLLPVQPSGQSEYLQQHVAGLQPPS 392
                PG A  +P+A  P    A P PQ PP     LL V PS  +    Q  A  +PP+
Sbjct: 803 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ--APRRPPT 860

Query: 393 PAQPSS-TGAAASPATAATLPVGTGQNASSV--GAQLMG----ASSQPSEAMAPRTGPAQ 445
           P   +S +G   + A A   P    ++ SS   G  L G    A+S P E     +GP  
Sbjct: 861 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 920

Query: 446 GGQVAPCQPTGV----PPATVGGVVQPCLGPAGAGQPQSVPPPQMGGS-----------G 490
           G   +P     +    P A   G   P       G P   PP    GS           G
Sbjct: 921 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 980

Query: 491 PLSAVPGGPHAVVPG 505
           P SA P  P A+ PG
Sbjct: 981 PESATP-APGALDPG 994



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 72/279 (25%), Positives = 91/279 (32%), Gaps = 64/279 (22%)

Query: 81   PGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLA 140
            P   +P  L    L A  + PA+  G       +    S LA     AP   A    Q+ 
Sbjct: 784  PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 843

Query: 141  GSS-AGPVTAAPSQPPT-----TCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSV 194
             S  A P   AP +PPT     + S     + L  G   P  R            S SS 
Sbjct: 844  PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR------------SPSST 891

Query: 195  LTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPP 254
            L+   D   HSS+   T E   G  +                GPE G      A +  PP
Sbjct: 892  LS-GPDLAGHSSSATSTPEELRGYDS----------------GPEGG------AAASPPP 928

Query: 255  SEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPP--FPGAATGPQPMMAAAQPS 312
              +++   PA                     A S  P PP  F GA   P P   A  P 
Sbjct: 929  DAELAACHPA---------------------AWSRGPAPPLAFRGAPGAPLPWPPATGPG 967

Query: 313  QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAA 351
               G     +T  P + T A  A+   P PG + G  AA
Sbjct: 968  SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 1006



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 80/319 (25%), Positives = 97/319 (30%), Gaps = 79/319 (24%)

Query: 390 PPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQV 449
           P SP  P     AA     A   VG    A   G   +G ++ P  A  PR GP +    
Sbjct: 30  PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG--IGGATIPESA--PRAGPTRSAGT 85

Query: 450 APCQPTGVPPAT----------------------VGGVVQPCLGPAG------------- 474
           +   P   PPA+                        G  +P  GP G             
Sbjct: 86  SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP--GPLGQKGLRISAEETVA 143

Query: 475 --------------AGQPQSVPPPQMGGSGPLSA--------VPGGPHAVVPGVPNVPAA 512
                         AG  +    P  G   P  A          G P       P  P  
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203

Query: 513 VPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRS-SSIIQHVGLPL-----APGTH 566
            P  SV S S  S T P+  A    S       P SRS SS    +  P      A GT 
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263

Query: 567 SAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSE----PLPQPPLSLIAENKPVVKP-PVA 621
            AP    Q      Q    P   QV   R+ +     PL   PL+  + +    +P P  
Sbjct: 264 RAPAHPSQPKPKGLQALRPP---QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP 320

Query: 622 DSLANPLQLT--PMNSLAT 638
           D+ A PL  T  P   LAT
Sbjct: 321 DNAATPLPATLPPSPPLAT 339



 Score = 33.5 bits (75), Expect = 0.78
 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 98   AAAPANGGGVVSARSVSGALASTLAAAATS-APAPGAPGGPQLAGSSAGPVTAAPSQ 153
            A  P +  G+ +     G  ++T A  A    P+PG  GG   AG+ AG  + +P Q
Sbjct: 963  ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 87.0 bits (214), Expect = 6e-17
 Identities = 136/553 (24%), Positives = 193/553 (34%), Gaps = 58/553 (10%)

Query: 38   ESRTEDVSSEIFDVSRATDYGPEE--------VCERSSSEETLNNVGDAETPGTVSPNLL 89
            E R  D    IF   + T  G  E        V +R S    +  V DA      SP   
Sbjct: 798  ERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPE-- 855

Query: 90   LDGQLAAAAAAPANGGGVVSA-----------RSVSGALASTLAAAATSAPAPGAPGGPQ 138
             +G   AA  AP  G  VV+A            S+       + AAA SAP         
Sbjct: 856  -EGTSIAAVPAP-EGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVT 913

Query: 139  LAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYY----ERDSDSSV 194
            ++        AA S P  T  +    I  +  S        W  +       E D     
Sbjct: 914  VSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEG 973

Query: 195  LTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGT----DSSLTAVS 250
                   +      D  A R S       S    V + +    P +      + +  A +
Sbjct: 974  PVTPATTVHAPEEPDTAAVRVS-TPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1032

Query: 251  QLPPSEKMSQ----PTPAQPQSFSVGQPQPPPPPV-GGAVAQSSAPLPPFPGAATGPQPM 305
              PP E  S     PTP +P S +   P P  P     AV     P  P     T  +P 
Sbjct: 1033 VPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1092

Query: 306  M-AAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQI 364
              AAA P+  +   P      PT    A PA ++P    PA  A A   P++ A+P P +
Sbjct: 1093 SPAAAVPTPEEPTSPAAAV--PTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 365  PPGHLLPVQPSGQSEYLQQHVAGLQP----PSPAQPSSTGAAASPATAATLPVGTGQNAS 420
            P     P + +  +  +        P    P+PA+ +S  A  +     T P  +    +
Sbjct: 1151 P----TPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPA 1206

Query: 421  SVGAQLMGASSQPSEAMAPRTGPAQGGQVA--PCQPTGVPPATVGGVVQPCLGPAGAGQP 478
            ++ A L   +S P+ ++     PA        P +PT  P A V  + +P    A    P
Sbjct: 1207 AMVATLEEFTS-PAASVPTSEEPASLAAAVSNPEEPTS-PAAAVPTLEEPTSSAAAVLTP 1264

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGV--PNVP-AAVPAPSVPSVSTTSVTMPNVPA-P 534
            + +  P    S P    P  P A V  +  P  P AAVP P V ++   SV  P VPA P
Sbjct: 1265 EELSSP--AASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIP 1322

Query: 535  LAQSQQLSSHTPV 547
             A    +   +P+
Sbjct: 1323 AAAVPPMEEVSPI 1335



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 92/377 (24%), Positives = 135/377 (35%), Gaps = 51/377 (13%)

Query: 270  SVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQP---QGAGPGGQTLPP 326
            +V  P+   P V  A+ Q          A  G  P  AA   + P   +   P G   P 
Sbjct: 925  AVSSPEETAPAVAAAITQEGM------SAVAGFSPEWAALAITVPITEEDGTPEGPVTPA 978

Query: 327  TNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVA 386
            T V         P +P  A  A     P++ A P   +P     P +P+  +  +     
Sbjct: 979  TTV-------HAPEEPDTA--AVRVSTPEEPASPAAAVPT----PEEPTSPAAAV----- 1020

Query: 387  GLQPPSPAQPSSTGAAASPATAATLP---VGTGQNASSVGAQLMGASSQPSEAMAPRTGP 443
                P+P +P+S  AA  P    T P   V T +  +S  A +       S A A  T P
Sbjct: 1021 ----PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT-P 1075

Query: 444  AQGGQVAPCQPTGVPPATVGGVVQPCLGPAG--AGQPQSVPPPQMGGSGPLSAVPGGPHA 501
             +    A   PT   P +    V     P    A  P    P     + P    P  P A
Sbjct: 1076 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAA 1135

Query: 502  VVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPL 561
             VP  P  PA  PAP+VP+   ++     VP P   +   ++    + S+S    V    
Sbjct: 1136 AVP-TPEEPA-FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLE 1193

Query: 562  APGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAE-NKPVVKPPV 620
             P + +A    P + ++  +  T P           S P  + P SL A  + P  + P 
Sbjct: 1194 EPTSPAASVPTPAAMVATLEEFTSPAA---------SVPTSEEPASLAAAVSNP--EEPT 1242

Query: 621  ADSLANPLQLTPMNSLA 637
            + + A P    P +S A
Sbjct: 1243 SPAAAVPTLEEPTSSAA 1259


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 160/664 (24%), Positives = 227/664 (34%), Gaps = 136/664 (20%)

Query: 214 RDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKM-------SQPTPAQP 266
           R +  GA G  VV    +     GP +  + +  A  + PP+ +         +P P  P
Sbjct: 51  RAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSP 110

Query: 267 QSFSV-GQPQPP-----PPPVGGA-----------VAQSSAPLPPFPGAATGPQPMMAAA 309
           +   V   P PP     PPP G A           VA    P P  P    GP  + A A
Sbjct: 111 RRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170

Query: 310 QPSQPQGAGPG-------------GQTLPPTNVTL-----AQPAMSL------------- 338
            P    G GPG              QTL  +   L     A PA+SL             
Sbjct: 171 GPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK 230

Query: 339 PPQPG------PAVGA-----------PAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYL 381
           P  PG      P VGA           PAA  P   A   P  PP      +P G     
Sbjct: 231 PAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP 290

Query: 382 QQHVAGLQPPSPAQ-PSSTGAAASPATAATLPVG-TGQNASSVGAQLMGASSQPSEAMAP 439
                 + PP+ AQ   S GAA +PA AA  P G +GQ      A    A +   +A +P
Sbjct: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAA---AAPAPGVKAESP 347

Query: 440 RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAG---QPQSVPPPQMGGSGPLSAVP 496
           +         A       P +T   +V   +GP   G    P +VPPP  G   P     
Sbjct: 348 KRVVQAAPPAAQTLAASGPASTAASMV---IGPTMQGALPSPAAVPPPAPG--TPTGLPK 402

Query: 497 GGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQH 556
           G   AV   +   P A  +  + +  T +V  P +P P              ++ + IQ+
Sbjct: 403 GAAGAVTQSLSRTPTATTS-GIRATLTPTVLAPRLPQP-------------PQNPTNIQN 448

Query: 557 VGLP----LAPGTHSAPTSLPQSDLSQFQTQ--TQPLVGQVDDTRRKSEPLPQPPLSLIA 610
             LP    L    +     +PQ  L+Q Q Q   QP   Q     R + P   PP+ +  
Sbjct: 449 FQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQP---QTTMAPRPATPTSAPPVQIST 505

Query: 611 ENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTAF---YQAFHLNT 667
              P    P+      P  +    S A +    +  +       P        Q   L T
Sbjct: 506 VQAP--GTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGT 563

Query: 668 LKESKSLWDSASGGGVVAIDNKIEQAMDLVKS---------HLMYAVREEVEVLKEQIKE 718
               ++     +  G     +   + M+ VK           L  + ++  E     +KE
Sbjct: 564 ATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTET-AANVKE 622

Query: 719 LVER--NSLLERE---NALLKSLSSNDQLSQLP--------TQQANPGSTSQQQAVIAQP 765
           LV+   +  +E E   + L + L+S+ Q   +P         +Q  P S +  Q    QP
Sbjct: 623 LVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQP 682

Query: 766 PQPT 769
           P PT
Sbjct: 683 PPPT 686



 Score = 38.5 bits (88), Expect = 0.024
 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 5/86 (5%)

Query: 78  AETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGP 137
           AE+P  V        Q  AA+   +    +V   ++ GAL S    AA   PAPG P G 
Sbjct: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSP---AAVPPPAPGTPTG- 399

Query: 138 QLAGSSAGPVTAAPSQPPTTCSSRFR 163
            L   +AG VT + S+ PT  +S  R
Sbjct: 400 -LPKGAAGAVTQSLSRTPTATTSGIR 424



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 58/231 (25%), Positives = 78/231 (33%), Gaps = 33/231 (14%)

Query: 427 MGASSQPSEAMAPRTGP---AQGGQVAPCQPTGVPPATVG-GVVQPCLG-PAGAGQPQSV 481
           + AS+     +APRT     A  G +     +G P    G G   P  G P  A +P   
Sbjct: 33  LAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPA 92

Query: 482 PPPQMGGSGPLSAVPGGPHA---VVPGVPNVPAA-------------VPAPSVPSVSTTS 525
              + GG GP    PG P     +VP  P  PAA              P P+  +V+   
Sbjct: 93  GRARPGGGGPQR--PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGP 150

Query: 526 VTMPNVPA----PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQ 581
              P  PA    P A + +                 G P  PG  +A T    + L    
Sbjct: 151 EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPG--AAQTLNGSAALLNSH 208

Query: 582 TQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTP 632
               P V  V++      PLP+P     A    +  PP   + A P    P
Sbjct: 209 HAAAPAVSLVNNGPAALLPLPKP----AAPGTVIQTPPFVGAAAPPAPAAP 255



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 3/64 (4%)

Query: 96  AAAAAPANGGGVVSARSVSGA---LASTLAAAATSAPAPGAPGGPQLAGSSAGPVTAAPS 152
           AAAAAPA G    S + V  A    A TLAA+  ++ A     GP + G+   P    P 
Sbjct: 333 AAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPP 392

Query: 153 QPPT 156
            P T
Sbjct: 393 APGT 396



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 67/277 (24%), Positives = 92/277 (33%), Gaps = 40/277 (14%)

Query: 81  PGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPG-GPQL 139
           P    P    +G  A AA APA   G       +G        AA +APAPG     P+ 
Sbjct: 295 PAVPPPAAAQNGGSAGAAPAPAPAAG-----GPAGVSGQPGPGAAAAAPAPGVKAESPKR 349

Query: 140 AGSSAGPV--TAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTR 197
              +A P   T A S P +T +S      +      P        +      + + +   
Sbjct: 350 VVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSP------AAVPPPAPGTPTGLPKG 403

Query: 198 SGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEK 257
           +   +  S +   TA   SG+ AT    V+     Q    P +  +  L     L  SE 
Sbjct: 404 AAGAVTQSLSRTPTA-TTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSEN 462

Query: 258 -----MSQPTPAQPQSFSVGQPQ------PPPPPVGGAVAQSSAPLPPFPGAATGPQPMM 306
                + Q   AQ Q+ +  QPQ      P  P     V  S+   P  P  A    P  
Sbjct: 463 GQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTT 522

Query: 307 AAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPG 343
              Q SQ Q              T  QP+ +L   PG
Sbjct: 523 IIKQVSQAQ--------------TTVQPSATLQRSPG 545


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 83.2 bits (204), Expect = 9e-16
 Identities = 142/555 (25%), Positives = 199/555 (35%), Gaps = 89/555 (16%)

Query: 247  TAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMM 306
            TA+ Q PP +      P  P     G P PPP P  G +     PLPP PGA   P P +
Sbjct: 894  TAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL-----PLPPLPGAGIPPPPPL 948

Query: 307  AAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPP 366
              A    P      G  LPP       P    PP P P  G P          P P   P
Sbjct: 949  PGAAIPPPPPLPGAGIPLPPPLPGAGIP----PPPPLPGAGIPPPPPLPGAGIPPPPPLP 1004

Query: 367  GHLLPVQP----SGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSV 422
            G  +P  P    +G         AG+ PP P  P +      P   A +P       + +
Sbjct: 1005 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGI 1063

Query: 423  --GAQLMGASSQPSE----AMAPRTGPAQGGQVAPCQP-TGV----PPATVGGVVQPCLG 471
                 L GA   P      A  P   P  G  + P  P  GV    PP   G  + P   
Sbjct: 1064 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1123

Query: 472  PAGAGQPQSVPPPQMGGSG-----PLSAV-----PGGPHAVVPGVPNVPAA--VPAPSVP 519
              GAG P   PPP + G+G     PL  V     P  P A +P  P +P A   P P +P
Sbjct: 1124 LPGAGIP---PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1180

Query: 520  SVS-TTSVTMPNV---PAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAP--TSLP 573
             V       +P V   P P      +    P       +  +G+P AP     P  T +P
Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLPGAGIPPPPP-------LPGMGIPPAPAPPLPPPGTGIP 1233

Query: 574  QSDLSQFQTQTQPLVGQVDDTRRKSEPLPQ------PPLSL----------IAENKPVVK 617
               L        PL+ QV  +   + P PQ      PPL                K  ++
Sbjct: 1234 PPPL--LPVSGPPLLPQVGSS---TLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIE 1288

Query: 618  P--PVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTLKESK--- 672
            P  P+       +QL      +TS+    I    +E       F + F    +KE K   
Sbjct: 1289 PCRPMKPLYWTRIQLHSKRDSSTSLIWEKI----EEPSIDCHEFEELFSKTAVKERKKPI 1344

Query: 673  --SLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLEREN 730
              ++  + +   V  + NK  QA+ ++ S L   +++    +      +V+    LE   
Sbjct: 1345 SDTISKTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVD----LETLQ 1400

Query: 731  ALLKSLSSNDQLSQL 745
            AL ++ + +D+L ++
Sbjct: 1401 ALYENRAQSDELEKI 1415



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 84/318 (26%), Positives = 109/318 (34%), Gaps = 91/318 (28%)

Query: 254  PSEKMSQPTPAQPQSFSVGQPQ-------------------------------PPPPPVG 282
            P++ +SQP P     +S GQ Q                               P PPP+ 
Sbjct: 803  PTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862

Query: 283  GAVAQSS--------APLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQP 334
               + SS         P PP PG      P  A  QP   QG     + LPP        
Sbjct: 863  CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT----EMLPP-------- 910

Query: 335  AMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPA 394
                PP P P  G P          P P +P   +LP+ P           AG+ PP P 
Sbjct: 911  ----PPPPLPGAGIP----------PPPPLPGAGILPLPPLPG--------AGIPPPPPL 948

Query: 395  QPSSTGAAASPATAATLPVGTGQNASSV--GAQLMGASSQPSE----AMAPRTGPAQGGQ 448
             P +      P   A +P+      + +     L GA   P      A  P   P  G  
Sbjct: 949  -PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1007

Query: 449  VAPCQP---TGV--PPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVV 503
            + P  P    G+  PP   G  + P     GAG P   PPP + G+G +   P  P A +
Sbjct: 1008 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLPGAG-IPPPPPLPGAGI 1063

Query: 504  PGVPNVPAA--VPAPSVP 519
            P  P +P A   P P +P
Sbjct: 1064 PPPPPLPGAGIPPPPPLP 1081



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 74/277 (26%), Positives = 100/277 (36%), Gaps = 37/277 (13%)

Query: 253  PPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPS 312
            PP    ++ + + P    +G   PPPPP+ G        +P  P  A    P +   +  
Sbjct: 858  PPPLPCTESSSSMP---GLGMVPPPPPPLPGMT------VPTLPSTAIPQPPPLQGTEML 908

Query: 313  QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPV 372
             P      G  +PP         + LPP PG   G P        A P P   PG  +P+
Sbjct: 909  PPPPPPLPGAGIPPPPPLPGAGILPLPPLPG--AGIPPPPPLPGAAIPPPPPLPGAGIPL 966

Query: 373  QPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSV--GAQLMGAS 430
             P           AG+ PP P  P +      P   A +P       + +     L GA 
Sbjct: 967  PPPLPG-------AGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1018

Query: 431  SQPSE----AMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQM 486
              P      A  P   P  G  + P      PP   G  + P     GAG P   PPP +
Sbjct: 1019 IPPPPPLPGAGIPPPPPLPGAGIPP------PPPLPGAGIPPPPPLPGAGIP---PPPPL 1069

Query: 487  GGSGPLSAVPGGPHAVVPGVPNVPAA--VPAPSVPSV 521
             G+G +   P  P A +P  P +P A   P P +P V
Sbjct: 1070 PGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1105



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 52/165 (31%), Positives = 54/165 (32%), Gaps = 20/165 (12%)

Query: 246  LTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPL------PPFPGAA 299
            L  V   PP        P  P     G P PPP P  G       P       PP PGA 
Sbjct: 1102 LPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG 1161

Query: 300  -TGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSL------PPQPGPAVGAPAAQ 352
               P P+  A  P  P   G G    PP       P   L      PP P P +G P A 
Sbjct: 1162 IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP 1221

Query: 353  QPQQFAYPQPQIPPGHLLPVQ------PSGQSEYLQQHVAGLQPP 391
             P     P   IPP  LLPV         G S      V G  PP
Sbjct: 1222 AP-PLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPP 1265



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 33/102 (32%), Positives = 37/102 (36%), Gaps = 7/102 (6%)

Query: 246  LTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPM 305
            L  V   PP        P  P     G P PPP P  G     + PLPP PG    P P+
Sbjct: 1179 LPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP-PGTGIPPPPL 1237

Query: 306  MAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVG 347
            +  + P  P     G  TLP   V    P    PP P    G
Sbjct: 1238 LPVSGP--PLLPQVGSSTLPTPQVCGFLP----PPLPSGLFG 1273



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 71/282 (25%), Positives = 99/282 (35%), Gaps = 68/282 (24%)

Query: 242 TDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAP-LP------- 293
           T+ +L+A+S LP S        A+P+       +P  PP  G +  S AP LP       
Sbjct: 269 TEQALSALSDLPES------LAAEPR-------EPQQPPSPGGLPVSEAPSLPAAQPAAK 315

Query: 294 --------PFPGAATGPQ----PMMAAAQPSQ----------PQGAGPGGQTLPPTNVTL 331
                   PFP A  G +    P+  A    +          P+G+ PG +  P      
Sbjct: 316 DSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGS-PGEEWAPEVGEDA 374

Query: 332 AQPAMSLPPQPGPAVGAPAAQQ------PQQFAY-PQPQIPPGHL--------LPVQPSG 376
            Q     P +      APAA        P Q  + P P I P ++         P     
Sbjct: 375 PQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPS 434

Query: 377 QSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEA 436
           QS      +     PS ++ S T  A+  A A       G  A       +  S+  +E 
Sbjct: 435 QSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAG------LSRSADWTEE 488

Query: 437 MAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQP 478
           +  RT P  GG  A     GV  +  GG V P L    +G P
Sbjct: 489 LGART-PRVGGS-AHLLERGV-ASDSGGGVSPALAAKASGAP 527



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 36/129 (27%), Positives = 53/129 (41%), Gaps = 18/129 (13%)

Query: 256 EKMSQPTPAQPQSFS-VGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQP 314
           E  + PT   PQ  + +G  +    P GGA     +P      +A    P   AA+P +P
Sbjct: 231 EPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREP 290

Query: 315 -QGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL---L 370
            Q   PGG  LP +      P++       PA    A   P   A+P P+  PG      
Sbjct: 291 QQPPSPGG--LPVSEA----PSL-------PAAQPAAKDSPSSTAFPFPEAGPGEEAAGA 337

Query: 371 PVQPSGQSE 379
           PV+ +G ++
Sbjct: 338 PVRGAGDTD 346



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 30/115 (26%), Positives = 42/115 (36%), Gaps = 14/115 (12%)

Query: 491 PLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRS 550
           P+  +PG P       P  P A   P     S  S+    + +P   S QL SH P    
Sbjct: 759 PVDGLPGRP-------PCPPGAESGPQTKFCSEISL----IVSPRRISVQLDSHQPTQSI 807

Query: 551 SSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPP 605
           S       L  + G     +  P S  ++FQT  +     V    + S  +P PP
Sbjct: 808 SQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHE---HSVSSAFKNSCNIPSPP 859


>gi|62865625 TSC22 domain family, member 3 isoform 3 [Homo sapiens]
          Length = 77

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 46/88 (52%), Positives = 58/88 (65%), Gaps = 14/88 (15%)

Query: 694 MDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQANPG 753
           MDLVK+HLMYAVREEVE+LKEQI+ELVE+NS LEREN LLK+L+S +QL +         
Sbjct: 1   MDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKF-------- 52

Query: 754 STSQQQAVIAQPPQPTQP--PQQPNVSS 779
               Q  +  + P P  P  P+ P  S+
Sbjct: 53  ----QSCLSPEEPAPESPQVPEAPGGSA 76


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 106/409 (25%), Positives = 150/409 (36%), Gaps = 54/409 (13%)

Query: 251 QLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQ 310
           Q PP+  +S P P   Q     QP   P P   A  Q++ P  P PG A+ P+ ++    
Sbjct: 626 QAPPA--VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLASSPEKIVLGQP 682

Query: 311 PSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLL 370
           PS            P   +T     M LP +         +QQP     P   +P   ++
Sbjct: 683 PS----------ATPTAILTQDSLQMFLPQE--------RSQQPLSAEGPHLSVPASVIV 724

Query: 371 PVQPSGQSEYLQQHV---AGLQPPSP-AQPSSTGAAASPATAATLPVGTGQNASSVGAQL 426
              P  Q       V   AGL P +P +Q S   A   PA A     G   + S      
Sbjct: 725 SAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAP 784

Query: 427 MGAS---SQPSEAMAPRTGPAQGGQVA---------PCQPTGVPPATVG-GVVQPCLG-- 471
           +G S     P     P   P++   V+         PC P   PP   G  V+Q  LG  
Sbjct: 785 LGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP 844

Query: 472 PAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNV 531
           P  +    + P P      P S  P GP   +P  P++P   P+ +  +V+++S T   +
Sbjct: 845 PPASNPAPTAPGPPQPPLRPQSQPPEGP---LPPAPHLP---PSSTSSAVASSSETSSRL 898

Query: 532 PAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQV 591
           PAP     QL          S      L L P   + P   P++    FQ  T P    +
Sbjct: 899 PAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRT----FQMVTTPFPA-L 953

Query: 592 DDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSV 640
              +   E   Q P  +I +NK    P    +  +   L P+ S A SV
Sbjct: 954 PQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTS---LGPLTSPAASV 999



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 129/523 (24%), Positives = 182/523 (34%), Gaps = 78/523 (14%)

Query: 114 SGALASTLAAAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGE 173
           +G     +  +   APA  A    Q   ++ G   AAP QPP   S    V  L+ GS  
Sbjct: 402 AGKAGQNVVLSGFPAPALQANVFKQPPATTTG---AAPPQPPGALSKPMSVHLLNQGSSI 458

Query: 174 PYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQ 233
                               +L      +   +   Q  ++ S L A  G  ++  A+  
Sbjct: 459 VIPA--------------QHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAA-- 502

Query: 234 GAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLP 293
               P +G         QL  +  ++    A P   S+G    P      A   S+AP+ 
Sbjct: 503 ----PHTG--------GQLIANPILTNQNLAGP--LSLGPVLAPHSGAHSAHILSAAPIQ 548

Query: 294 PF-PGAATGPQPMMAAAQP--SQPQGAGPG------GQTLPPTNVTLAQPAMSLPPQPGP 344
              P     P  + A + P  SQP  AGP       G TLPP+ V +      L  QP  
Sbjct: 549 VGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLV-QPAT 607

Query: 345 AVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAAS 404
              A     P     P PQ PP    P+    Q    QQ      P + A P +T    S
Sbjct: 608 PAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPS 667

Query: 405 PATAAT-LPVGTGQNASSVGAQLM-----------GASSQPSEAMAPRTGPAQGGQVAPC 452
           P  A++   +  GQ  S+    ++             S QP  A  P         +   
Sbjct: 668 PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLS-VPASVIVSA 726

Query: 453 QPTGVPPATVGGVVQPC-LGP-AGAGQPQSVPPPQMGGSGPL-----SAVPGGPH-AVVP 504
            P    PA    V +   LGP A   Q    P PQ+  + PL     S+ P  PH A + 
Sbjct: 727 PPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLG 786

Query: 505 GVPNVPAAVPA--PSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLA 562
             P++P+  P   PS P     SV+ P    PL       +   +     I   +G+P  
Sbjct: 787 DSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP-P 845

Query: 563 PGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPP 605
           P ++ APT+ P       + Q+QP  G          PLP  P
Sbjct: 846 PASNPAPTA-PGPPQPPLRPQSQPPEG----------PLPPAP 877



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 89/361 (24%), Positives = 128/361 (35%), Gaps = 64/361 (17%)

Query: 227  VVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVA 286
            V+V++   A  P   T  +  A   L P    SQ +PA         P   P P      
Sbjct: 722  VIVSAPPPAQDPAPATPVAKGA--GLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSL 779

Query: 287  QSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTL--AQPAMSLPPQPGP 344
               APL   P   +       +  PS+PQ       + PP+   L    P  + P  PG 
Sbjct: 780  PHQAPLGDSPHLPSPHPTRPPSRPPSRPQSV-----SRPPSEPPLHPCPPPQAPPTLPGI 834

Query: 345  AVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQP---SSTGA 401
             V       P   + P P  P     P++P  Q         G  PP+P  P   +S+  
Sbjct: 835  FVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPP------EGPLPPAPHLPPSSTSSAV 888

Query: 402  AASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPAT 461
            A+S  T++ LP  T                 PS+    +  P+QG   +P      PP T
Sbjct: 889  ASSSETSSRLPAPT-----------------PSDFQL-QFPPSQGPHKSP-----TPPPT 925

Query: 462  VGGVVQPCLGPAGAGQPQSVPPPQ--MGGSGPLSAVPGGPHAVVPGVPNVPAAV------ 513
            +  V +P   P         PPP+     + P  A+P  P A++     VP+ +      
Sbjct: 926  LHLVPEPAAPPP--------PPPRTFQMVTTPFPALP-QPKALLERFHQVPSGIILQNKA 976

Query: 514  -PAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSL 572
              AP+ P  ST+   + +  A +  S Q  S TP + S     H   P        P  L
Sbjct: 977  GGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPS-----HAPAPAPMAATGLPPLL 1031

Query: 573  P 573
            P
Sbjct: 1032 P 1032



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 79/288 (27%), Positives = 104/288 (36%), Gaps = 52/288 (18%)

Query: 253  PPSEKMSQPT-----PAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMA 307
            PPS   S+P      P++P       PQ PP   G  V Q+   +PP P +   P     
Sbjct: 799  PPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP-PASNPAPTAPGP 857

Query: 308  AAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP----- 362
               P +PQ   P G  LP        PA  LPP    +  A +++   +   P P     
Sbjct: 858  PQPPLRPQSQPPEG-PLP--------PAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQL 908

Query: 363  QIPPG---HLLPVQPSGQSEYLQQHVAGLQPPSPA--QPSSTGAAASPATAATL------ 411
            Q PP    H  P  P   + +L    A   PP P   Q  +T   A P   A L      
Sbjct: 909  QFPPSQGPHKSPTPP--PTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQV 966

Query: 412  PVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLG 471
            P G      + GA    A+ Q S ++ P T PA    V+   P+G P A       P   
Sbjct: 967  PSGIILQNKAGGAP---AAPQTSTSLGPLTSPAASVLVSGQAPSGTPTA-------PSHA 1016

Query: 472  PAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVP 519
            PA         P  M  +G    +P    A    +P +  A  A S P
Sbjct: 1017 PA---------PAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 68/240 (28%), Positives = 86/240 (35%), Gaps = 50/240 (20%)

Query: 226  VVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAV 285
            + V+ +  G   P S    +     Q PP    SQP    P+      P  PP     AV
Sbjct: 834  IFVIQNQLGVPPPASNPAPTAPGPPQ-PPLRPQSQP----PEGPLPPAPHLPPSSTSSAV 888

Query: 286  AQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGP- 344
            A SS      P  A  P        PSQ    GP     PP  + L  P  + PP P P 
Sbjct: 889  ASSSETSSRLP--APTPSDFQLQFPPSQ----GPHKSPTPPPTLHLV-PEPAAPPPPPPR 941

Query: 345  -----AVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSST 399
                     PA  QP+       Q+P G +L            Q+ AG  P +P   +S 
Sbjct: 942  TFQMVTTPFPALPQPKALLERFHQVPSGIIL------------QNKAGGAPAAPQTSTSL 989

Query: 400  GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPP 459
            G   SPA +  +   +GQ  S       G  + PS A AP          AP   TG+PP
Sbjct: 990  GPLTSPAASVLV---SGQAPS-------GTPTAPSHAPAP----------APMAATGLPP 1029



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 111/469 (23%), Positives = 156/469 (33%), Gaps = 97/469 (20%)

Query: 234 GAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPP----------PPPVGG 283
           G  G   G D     + Q      +++ T        +G  Q P          P   GG
Sbjct: 89  GGGGGSGGADQPCDILQQSLQEANITEQTLEAEAELDLGPFQLPTLQPADGGAGPTGAGG 148

Query: 284 AVAQSSAPLPPFPG-----------------AATGPQPMMAAAQPSQP--QGAGPGGQTL 324
           A A ++ P   FPG                 A   PQ ++  A   QP  Q  G G  TL
Sbjct: 149 AAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSVQPFLQPVGLGNVTL 208

Query: 325 PP---------------TNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
            P               T  TL    + +  QP  A+  P +Q   +      Q+P    
Sbjct: 209 QPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAK------QVPVSGY 262

Query: 370 LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPAT------------AATLPVGTGQ 417
           L    +G SE +    AG+ P           +A+ AT            AA+ P GT  
Sbjct: 263 L-ASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPS 321

Query: 418 NASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ--PTGVPPATVGGVVQPCLGPAGA 475
                G  L  A    S  + P           P Q  P GV P  +  +      PAGA
Sbjct: 322 -----GQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGA 376

Query: 476 -----GQPQSVP--PPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTM 528
                G+P ++P  P        ++A   G + V+ G P           P  +TT    
Sbjct: 377 TLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAP 436

Query: 529 PNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTS----LPQSDLSQFQTQT 584
           P  P  L  S+ +S H  +++ SSI+        P  H  P      LP +   Q   Q 
Sbjct: 437 PQPPGAL--SKPMSVHL-LNQGSSIV-------IPAQHMLPGQNQFLLPGAPAVQLPQQL 486

Query: 585 QPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPM 633
             L   V   +  +   P     LIA   P++      +LA PL L P+
Sbjct: 487 SALPANVGG-QILAAAAPHTGGQLIA--NPIL---TNQNLAGPLSLGPV 529



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 50/205 (24%), Positives = 66/205 (32%), Gaps = 44/205 (21%)

Query: 230  ASMQGAHGPESGTDSSLTAVS------QLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGG 283
            +S   A    S T S L A +      Q PPS+   +     P    V +P  PPPP   
Sbjct: 882  SSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPR 941

Query: 284  AVAQSSAPLPPFP-----------------------GAATGPQ------PMMAAAQPSQP 314
                 + P P  P                       GA   PQ      P+ + A     
Sbjct: 942  TFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLV 1001

Query: 315  QGAGPGGQTLPPTNVTLAQP--AMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPV 372
             G  P G    P++     P  A  LPP       A A+  P           PG     
Sbjct: 1002 SGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPG----- 1056

Query: 373  QPSGQSEYLQQHVAGLQPPSPAQPS 397
            +PSG     +  ++GL+ P   QPS
Sbjct: 1057 KPSGLQ--YESKLSGLKKPPTLQPS 1079



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 64/264 (24%), Positives = 89/264 (33%), Gaps = 34/264 (12%)

Query: 243  DSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPP---FPGAA 299
            ++ L+ V      + + QP P  P +  V +P P PPP          P PP     G  
Sbjct: 1315 EAGLSKVVHNTALDPVHQPPPP-PATLKVAEPPPRPPP----------PPPPTGQMNGTV 1363

Query: 300  TGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAY 359
              P P   AA   +P G  P    LP     L +        PG   G PA +       
Sbjct: 1364 DHPPP---AAPERKPLGTAPHCPRLP-----LRKTYRENVGGPGAPEGTPAGRARGGSPA 1415

Query: 360  PQP---QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTG 416
            P P         L+    + + E  Q+ + G  PP PA  ++ G       A  LP    
Sbjct: 1416 PLPAKVDEATSGLIRELAAVEDELYQRMLKG-PPPEPAASAAQGTGDPDWEAPGLPPAKR 1474

Query: 417  QNASS--VGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAG 474
            + + S  V      + S   + +      A    +   Q  G  PA            A 
Sbjct: 1475 RKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPA------PSYPHAAS 1528

Query: 475  AGQPQSVPPPQMGGSGPLSAVPGG 498
            AG P S PP     + P S+  GG
Sbjct: 1529 AGTPASPPPLHRPEAYPPSSHNGG 1552



 Score = 33.5 bits (75), Expect = 0.78
 Identities = 51/231 (22%), Positives = 74/231 (32%), Gaps = 28/231 (12%)

Query: 325  PPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQ-- 382
            PP  + +A+P    PP P      P  Q      +P P  P    L   P      L+  
Sbjct: 1336 PPATLKVAEPPPRPPPPP-----PPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKT 1390

Query: 383  --QHVAGLQPPSPAQPSSTGAA-ASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMA- 438
              ++V G     P  P  T A  A   + A LP    +  S +  +L     +  + M  
Sbjct: 1391 YRENVGG-----PGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLK 1445

Query: 439  -----PRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLS 493
                 P    AQG      +  G+PPA       P +  A        P          S
Sbjct: 1446 GPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDS--PQDDTLTEHLQS 1503

Query: 494  AVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544
            A+       +  +   P   PAPS P  ++        P    ++   SSH
Sbjct: 1504 AIDS-----ILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSH 1549


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 92/404 (22%), Positives = 135/404 (33%), Gaps = 51/404 (12%)

Query: 247  TAVSQLPPSEKMSQPTPAQPQSFSVGQPQPP------PPPV---GGAVAQSSAPLP---P 294
            T+ + LPP+   S PT           P PP      PPP       ++ ++ P P   P
Sbjct: 1411 TSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTP 1470

Query: 295  FPGAATGPQPMMAAAQPSQPQGAGPGGQT-LPPTNVTLAQPAMS--LPPQPGPAVGAPAA 351
             P   T   P    + P+      P   T  PPT   +  PA +  LPP   P+      
Sbjct: 1471 SPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTT 1530

Query: 352  QQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPS--PAQPSSTGAAASPATAA 409
              P     P P        P+ P   +  L        PP+  P+ P +T     P T  
Sbjct: 1531 TTPPPTTTPSPPTTT----PITPPTSTTTL--------PPTTTPSPPPTTTTTPPPTTTP 1578

Query: 410  TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPC 469
            + P  T  +  ++       ++ PS      T P      +P   T + P T    + P 
Sbjct: 1579 SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1638

Query: 470  LGPAGAGQPQSVPPPQMGGSGPLSAVPGGP-HAVVPGVPNVPAAVPAPSVPSVSTTSVTM 528
              P+      + PPP    S P +  P  P        P    + P  + PS  TT++T 
Sbjct: 1639 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTT 1698

Query: 529  PNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLV 588
            P+ P     S   ++ TP S ++        P    T  +PT+ P    +   T      
Sbjct: 1699 PS-PTTTPSSPITTTTTPSSTTTP-----SPPPTTMTTPSPTTTPSPPTTTMTTLPPTTT 1752

Query: 589  GQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTP 632
                     S PL   PL       P + PP     +     TP
Sbjct: 1753 ---------SSPLTTTPL------PPSITPPTFSPFSTTTPTTP 1781



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 71/311 (22%), Positives = 96/311 (30%), Gaps = 37/311 (11%)

Query: 238  PESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPP-----PPVGGAVA--QSSA 290
            P + T S  T     PP+   + P    P   +     PPP     PP    +    S+ 
Sbjct: 1495 PPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1554

Query: 291  PLPPF------PGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGP 344
             LPP       P   T P P      PS P    P     PPT  T   P  + P  P  
Sbjct: 1555 TLPPTTTPSPPPTTTTTPPP---TTTPSPPTTTTPS----PPTITTTTPPPTTTPSPPTT 1607

Query: 345  AVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAAS 404
                P            P  PP     + P+              P +   P +T   + 
Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1667

Query: 405  PATAATLPVGTGQNASSV---GAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPAT 461
            P T  T P  T   +S +    +      + PS    P + P           T  PP T
Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP-SSPITTTTTPSSTTTPSPPPT 1726

Query: 462  VGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSV 521
                  P   P+      +  PP    S PL+  P            +P ++  P+    
Sbjct: 1727 TMTTPSPTTTPSPPTTTMTTLPPTT-TSSPLTTTP------------LPPSITPPTFSPF 1773

Query: 522  STTSVTMPNVP 532
            STT+ T P VP
Sbjct: 1774 STTTPTTPCVP 1784



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 77/400 (19%), Positives = 116/400 (29%), Gaps = 31/400 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 4032 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 4089

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 4090 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 4148

Query: 370  LPVQPSGQSEYLQQHV---AGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQL 426
             P      +           G Q P+    ++T       T      G   + S+     
Sbjct: 4149 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAE 4208

Query: 427  MGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQM 486
            +  S+ P E+  P+T  +    +           T+   + P +       P +   P  
Sbjct: 4209 LTTSNPPPESSTPQTSRSTSSPLTES-------TTLLSTLPPAIEMTSTAPPSTPTAPTT 4261

Query: 487  GGSGPLSAVPGGPHAVVPGVPNV-----PAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQL 541
               G   + P       PG P        ++ P PS    +TTS   P  P PL+    +
Sbjct: 4262 TSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT-PTPLSTPSII 4320

Query: 542  SSHTPVSRSSSII---------QHVGLPLAPGTHSAPTSLPQSDLS---QFQTQTQPLVG 589
             +       SS++            G  +  GT+          LS   +F   + P   
Sbjct: 4321 RTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTP 4380

Query: 590  QVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQ 629
                T  KS P P  P S  ++  P  KPP       P Q
Sbjct: 4381 SPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQ 4420



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 69/352 (19%), Positives = 116/352 (32%), Gaps = 34/352 (9%)

Query: 238  PESGTDSSLTAVSQLPPSEKMSQP---TPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPP 294
            P + T S  T     PP+   + P   TP+ P + +      PPP    +   ++ P PP
Sbjct: 1613 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT----TPPPTTTPSPPTTTTPSPP 1668

Query: 295  FPGAATGP------QPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQ-PAMSLPPQPGPAVG 347
                 T P       P+     P       P   T P + +T    P+ +  P P P   
Sbjct: 1669 ITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTT- 1727

Query: 348  APAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPAT 407
                  P     P P  P   +  + P+  S  L        PPS   P+ +  + +  T
Sbjct: 1728 ---MTTPSPTTTPSP--PTTTMTTLPPTTTSSPLTTTPL---PPSITPPTFSPFSTTTPT 1779

Query: 408  AATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQ 467
               +P+         G          +E +    GP     ++ C+ T  P   +G + Q
Sbjct: 1780 TPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANIS-CRATMYPDVPIGQLGQ 1838

Query: 468  PCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGP------HAVVPGVPNVPAAVPAPSVPSV 521
              +     G        + GG  P++              V             P+ P+ 
Sbjct: 1839 TVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTT 1898

Query: 522  STTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            +  + T    P P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 1899 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 1946



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 46/204 (22%), Positives = 67/204 (32%), Gaps = 15/204 (7%)

Query: 433  PSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPL 492
            PS      + P       P   T  PP T      P   P+      + PPP    S P+
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458

Query: 493  SAVPGGPHAVVPGVPNVPAAVP--APSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRS 550
            S     P    P  P    + P   PS P+ +TT+      P+P        + TP++  
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP-------PTTTPITPP 1511

Query: 551  SSIIQHVGLP--LAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSL 608
            +S      LP    P   +  T+ P    +     T P+      T       P PP + 
Sbjct: 1512 AST---TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568

Query: 609  IAENKPVVKP-PVADSLANPLQLT 631
                 P   P P   +  +P  +T
Sbjct: 1569 TTTPPPTTTPSPPTTTTPSPPTIT 1592



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 1962 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2019

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2020 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2078

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2079 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2135

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2136 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2195

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2196 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2255

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 2256 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2291



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2031 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2088

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2089 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2147

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2148 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2204

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2205 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2264

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2324

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 2325 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2360



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2100 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2157

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2158 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2216

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2217 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2273

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2274 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2333

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2334 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2393

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 2394 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2429



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2169 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2226

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2227 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2285

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2286 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2342

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2343 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2402

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2462

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 2463 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2498



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2238 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2295

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2296 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2354

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2355 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2411

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2412 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2471

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2472 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2531

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 2532 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2567



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2307 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2364

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2365 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2423

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2424 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2480

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2481 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2540

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2541 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2600

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 2601 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2636



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2376 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2433

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2434 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2492

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2493 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2549

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2550 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2609

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2610 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2669

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 2670 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2705



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2445 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2502

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2503 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2561

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2562 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2618

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2619 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2678

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2679 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2738

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 2739 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2774



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2514 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2571

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2572 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2630

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2631 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2687

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2688 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2747

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2748 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2807

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 2808 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2843



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2583 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2640

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2641 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2699

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2700 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2816

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2876

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 2877 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2912



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2652 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2709

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2710 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2768

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2769 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2825

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2826 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2885

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2886 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2945

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 2946 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 2981



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2721 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2778

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2779 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2837

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2838 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2894

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2895 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2954

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3014

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3015 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3050



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2790 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2847

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2848 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2906

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2907 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2963

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 2964 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3023

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3024 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3083

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3084 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3119



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2859 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2916

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2917 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 2975

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 2976 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3032

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3033 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3092

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3093 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3152

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3153 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3188



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2928 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 2985

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 2986 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3044

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3045 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3101

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3102 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3161

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3162 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3221

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3222 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3257



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 2997 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3054

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3055 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3113

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3114 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3170

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3171 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3230

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3290

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3291 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3326



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 3066 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3123

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3124 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3182

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3183 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3239

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3240 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3299

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3300 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3359

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3360 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3395



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 3135 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3192

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3193 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3251

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3252 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3308

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3309 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3368

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3369 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3428

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3429 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3464



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 3204 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3261

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3262 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3320

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3321 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3377

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3378 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3437

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3438 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3497

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3498 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3533



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 3273 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3330

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3331 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3389

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3390 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3446

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3447 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3506

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3507 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3566

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3567 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3602



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 3342 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3399

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3400 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3458

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3459 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3515

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3516 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3575

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3576 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3635

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3636 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3671



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 3411 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3468

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3469 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3527

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3528 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3584

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3585 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3644

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3645 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3704

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3705 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3740



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 3480 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3537

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3596

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3597 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3653

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3654 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3713

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3714 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3773

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3774 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3809



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 3549 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3606

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3607 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3665

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3666 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3722

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3723 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3782

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3783 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3842

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3843 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3878



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 3618 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3675

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3676 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3734

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3735 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3791

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3792 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3851

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3852 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3911

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3912 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 3947



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 3687 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3744

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3745 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3803

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3804 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3860

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3861 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3920

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3980

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 3981 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 4016



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 66/340 (19%), Positives = 97/340 (28%), Gaps = 26/340 (7%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 3756 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 3813

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P  P G  
Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3872

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVG----AQ 425
             P      +      V     P+  Q  +T    +  T    P  TG    +        
Sbjct: 3873 TPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3929

Query: 426  LMGASSQPSEAMAPRTGP-AQGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQP 478
             +  +  P+    P T P      V P   PTG       P T    V P   P G   P
Sbjct: 3930 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3989

Query: 479  QSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPA 533
             + P        P     G        +       P P+      P+ +  + T    P 
Sbjct: 3990 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4049

Query: 534  PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            P     Q  + TP++ ++++      P   GT + PT+ P
Sbjct: 4050 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQT-PTTTP 4085



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 61/329 (18%), Positives = 91/329 (27%), Gaps = 27/329 (8%)

Query: 250  SQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAA 309
            +Q P +  ++  T   P     G   P   P+      +  P P   G  T     +   
Sbjct: 1916 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTT 1973

Query: 310  QPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL 369
                P     G QT   T +T        P   G                P P       
Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------ 2027

Query: 370  LPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGA 429
                P+G        +      +P  P+ TG      T  T         +  G Q    
Sbjct: 2028 ----PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2082

Query: 430  SSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGS 489
            +   +      T    G Q     PT   P T    V P   P G   P + P       
Sbjct: 2083 TPITTTTTVTPTPTPTGTQT----PT-TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2137

Query: 490  GPLSAVPGGPHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPAPLAQSQQLSSH 544
             P     G        +       P P+      P+ +  + T    P P     Q  + 
Sbjct: 2138 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2197

Query: 545  TPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
            TP++ ++++      P   GT + PT+ P
Sbjct: 2198 TPITTTTTV---TPTPTPTGTQT-PTTTP 2222



 Score = 33.9 bits (76), Expect = 0.60
 Identities = 96/500 (19%), Positives = 146/500 (29%), Gaps = 60/500 (12%)

Query: 126  TSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEY 185
            T+ P P     P    ++  P T  PS P TT  +          +  P      T    
Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1652

Query: 186  YERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSS 245
                      T     I  ++T   T    S +  T       + +      P S   ++
Sbjct: 1653 PTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712

Query: 246  LTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPP------PPVGGAVAQSSAPLPPF---- 295
             T  S   PS   +  T   P +     P PP       PP   +   ++ PLPP     
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTT----TPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPP 1768

Query: 296  ---PGAATGPQPMMAAA-------QPSQPQGAGPGGQTL-------PPTNVTLAQPAMSL 338
               P + T P                 +P    PGG T        P     ++  A   
Sbjct: 1769 TFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMY 1828

Query: 339  PPQPGPAVGAPAAQQPQQ-FAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPS----- 392
            P  P   +G                   PG ++P+      E   Q    +  P+     
Sbjct: 1829 PDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTT 1888

Query: 393  ----PAQPSSTGAAASPATAAT-LPVGTGQNASS--VGAQLMGASSQPSEAMAPRTGP-A 444
                P  P++T    +     T  P GT    ++       +  +  P+    P T P  
Sbjct: 1889 TTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1948

Query: 445  QGGQVAPCQ-PTGVP-----PATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGG 498
                V P   PTG       P T    V P   P G   P + P        P     G 
Sbjct: 1949 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2008

Query: 499  PHAVVPGVPNVPAAVPAPS-----VPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSI 553
                   +       P P+      P+ +  + T    P P     Q  + TP++ ++++
Sbjct: 2009 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2068

Query: 554  IQHVGLPLAPGTHSAPTSLP 573
                  P   GT + PT+ P
Sbjct: 2069 ---TPTPTPTGTQT-PTTTP 2084


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 81/266 (30%), Positives = 89/266 (33%), Gaps = 43/266 (16%)

Query: 253 PPSEKMSQPTPAQPQSFSV----GQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPM--- 305
           PP  K   P P   +S S     G+PQ PPP  G    Q   P PP PG   GP P    
Sbjct: 72  PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN---QPQGPPPP-PGKPQGPPPQGGN 127

Query: 306 --MAAAQPSQPQGAGPGGQTL-----PPTNVTLAQPAMSLPPQ-PGPAVGAPAAQQPQQF 357
                  P +PQG  P G        PP       P     PQ P P  G P    PQ  
Sbjct: 128 RPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 187

Query: 358 AYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQ--------------PPSPAQPSSTGAAA 403
             PQ   PPG      P G      Q   G                PP P +P       
Sbjct: 188 KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 247

Query: 404 SPATAATLPVGTGQNASSVG-AQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATV 462
                   P G  Q   + G ++   A S P +   P   P Q G      P G PP   
Sbjct: 248 GNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGP---PQQEGN----NPQGPPPPAG 300

Query: 463 GGVVQPCLGPAGAGQPQSVPPPQMGG 488
           G   QP   P  AGQPQ  P P  GG
Sbjct: 301 GNPQQPQAPP--AGQPQGPPRPPQGG 324



 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 83/291 (28%), Positives = 95/291 (32%), Gaps = 47/291 (16%)

Query: 254 PSEKMSQPTPAQPQSFSVGQPQPP-------PPPVGGAVAQSSAPLPPFPGAATGPQPM- 305
           PS     P    PQ  +  Q  PP       PPP GG   Q     PP PG   GP P  
Sbjct: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQG----PPPPGKPQGPPPQG 84

Query: 306 ----MAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPG------PAVGAPAAQQPQ 355
                  + P +PQG  P G   P             PPQ G      P  G P    PQ
Sbjct: 85  DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQ 144

Query: 356 QFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGT 415
                 P+ PPG      P G ++          PP P +P               P G 
Sbjct: 145 GDKSRSPRSPPGKPQGPPPQGGNQ------PQGPPPPPGKPQGPPPQGGKKPQGPPPPGK 198

Query: 416 GQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGA 475
            Q     G +   + S P +   P   P QGG     QP G PP        P   P G 
Sbjct: 199 PQGPPPQGDKSRSSQSPPGKPQGP---PPQGGN----QPQGPPPPPGKPQGPP---PQGG 248

Query: 476 GQPQSVP-------PPQMGGSGPLSA--VPGGPHAVVPGVPNVPAAVPAPS 517
            +PQ  P       PP  GGS   SA   PG P        N P   P P+
Sbjct: 249 NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA 299



 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 79/260 (30%), Positives = 94/260 (36%), Gaps = 37/260 (14%)

Query: 268 SFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPT 327
           S   G PQ P P  G    +   P PP PG   GP P       ++PQG  P G+   P 
Sbjct: 30  SLIAGNPQGPSPQGGN---KPQGPPPP-PGKPQGPPPQGG----NKPQGPPPPGKPQGPP 81

Query: 328 NVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAG 387
                Q   S  P+  P  G P    PQ    PQ   PP    P +P G          G
Sbjct: 82  ----PQGDKSRSPRSPP--GKPQGPPPQGGNQPQGPPPP----PGKPQGPPPQGGNRPQG 131

Query: 388 LQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGA-QLMGASSQPSEAMAPRTGPAQG 446
             PP P +P         + +   P G  Q     G  Q  G    P +   P   P QG
Sbjct: 132 --PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP---PPQG 186

Query: 447 GQ-----VAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLS--AVPGGP 499
           G+       P +P G PP   G   +    P   G+PQ  PPPQ GG+ P      PG P
Sbjct: 187 GKKPQGPPPPGKPQGPPPQ--GDKSRSSQSP--PGKPQG-PPPQ-GGNQPQGPPPPPGKP 240

Query: 500 HAVVPGVPNVPAAVPAPSVP 519
               P   N P   P P  P
Sbjct: 241 QGPPPQGGNKPQGPPPPGKP 260



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 82/311 (26%), Positives = 98/311 (31%), Gaps = 31/311 (9%)

Query: 304 PMMAAAQPSQPQGAG---PGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYP 360
           P + A  P  P   G   P G   PP       P     PQ  P  G P    PQ     
Sbjct: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88

Query: 361 QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNAS 420
            P+ PPG      P G ++          PP P +P               P G  Q   
Sbjct: 89  SPRSPPGKPQGPPPQGGNQ------PQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP 142

Query: 421 SVGAQLMGASSQPSEAMAPRTGPAQGGQ--VAPCQPTGVP--PATVGGVVQPCLGPAGAG 476
             G +     S P +   P   P QGG     P  P G P  P   GG  +   GP   G
Sbjct: 143 PQGDKSRSPRSPPGKPQGP---PPQGGNQPQGPPPPPGKPQGPPPQGG--KKPQGPPPPG 197

Query: 477 QPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAP--SVPSVSTTSVTMPNVPAP 534
           +PQ  PPPQ   S    + PG P    P   N P   P P              P  P P
Sbjct: 198 KPQG-PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 256

Query: 535 LAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDT 594
             + Q      P ++  S  Q    P  PG    P   PQ + +  Q    P  G     
Sbjct: 257 PGKPQ-----GPPAQGGSKSQSARSP--PGKPQGP---PQQEGNNPQGPPPPAGGNPQQP 306

Query: 595 RRKSEPLPQPP 605
           +      PQ P
Sbjct: 307 QAPPAGQPQGP 317



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 57/193 (29%), Positives = 71/193 (36%), Gaps = 32/193 (16%)

Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFP 296
           G +S +  S     Q PP +  +QP    P     G+PQ PPP  GG   Q     PP P
Sbjct: 145 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQ-GGKKPQG----PPPP 196

Query: 297 GAATGPQPM-----MAAAQPSQPQGAGPGGQTLP-----PTNVTLAQPAMSL-----PPQ 341
           G   GP P       + + P +PQG  P G   P     P       P         PP 
Sbjct: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 256

Query: 342 PGPAVGAPA--AQQPQQFAYP--QPQIPPGH-----LLPVQPSGQSEYLQQHVAGLQPPS 392
           PG   G PA    + Q    P  +PQ PP         P  P+G +    Q     QP  
Sbjct: 257 PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 316

Query: 393 PAQPSSTGAAASP 405
           P +P   G  + P
Sbjct: 317 PPRPPQGGRPSRP 329


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 108/415 (26%), Positives = 155/415 (37%), Gaps = 55/415 (13%)

Query: 244  SSLTAVSQLPPSEKMSQPTP-----AQPQSFSVGQPQPPPPPVGGAV---AQSSAPLP-- 293
            S L   S LP       P P     A P S +V  P     P+       A +SAPL   
Sbjct: 1399 SPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIP 1458

Query: 294  ---PFPGAATGPQPMMAAAQPSQPQ-GAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAP 349
               P   +A+GP  + +   P  P   A PG  +L P+  + +  A++L     P++ + 
Sbjct: 1459 ISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSS 1518

Query: 350  AAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAA 409
                            PGH L + P+        HV GL   S   P+ +     PA+A 
Sbjct: 1519 QT--------------PGHPLLLAPTSS------HVPGLN--STVAPACSPVLV-PASAL 1555

Query: 410  TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPC 469
              P  +  N +   A L+  +S  S+A+A    P    Q A   P+  PP     V+ P 
Sbjct: 1556 ASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPS 1615

Query: 470  LGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMP 529
             G A        P P M      S+ PG   A    VP  P  V APS    ST ++   
Sbjct: 1616 PGAAPVLASSQTPVPVMAP----SSTPGTSLASASPVP-APTPVLAPS----STQTMLPA 1666

Query: 530  NVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVG 589
             VP+PL      +S   ++ + ++   +G      T S  T  PQ           P   
Sbjct: 1667 PVPSPLPSP---ASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASS 1723

Query: 590  QVDDTRRKSEPLPQPPL----SLIAENKPVVKP--PVADSLANPLQLTPMNSLAT 638
             V    +     P PPL    +L     P + P  PV  + A+ L L P +S A+
Sbjct: 1724 LVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSAS 1778



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 120/497 (24%), Positives = 177/497 (35%), Gaps = 106/497 (21%)

Query: 237  GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQ-----PPPPPVGGAVAQ---- 287
            GPE     +   V Q+ P+  M   +PA P      +P      PP  P  G++ Q    
Sbjct: 1029 GPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPS 1088

Query: 288  -----SSAPLPPFPGAATGP-QPMMAAAQPSQPQGAG--------PGGQTLPP-----TN 328
                 S    PP P  +  P  P      P+ P G+         P G T PP     T+
Sbjct: 1089 PLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTS 1148

Query: 329  VTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYP---QPQIPPGHLLPVQPSGQSEYLQQHV 385
             T A    +  P P PA        PQ+       Q ++P G ++ +   GQ   L Q  
Sbjct: 1149 TTTATATTTAVPAPTPA--------PQRLILSPDMQARLPSGEVVSI---GQLASLAQRP 1197

Query: 386  ---AGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGAS------SQPS-- 434
               AG   P   Q        + A    L VG  +        L+ A       SQP+  
Sbjct: 1198 VANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHV 1257

Query: 435  ---EAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSG- 490
               +A+AP  GP     V P       PA  G  +     P  A Q   VPP  +  +G 
Sbjct: 1258 ALIQAVAPTPGPTP-VSVLPSSTPSTTPAPTGLSL-----PLAANQ---VPPTMVNNTGV 1308

Query: 491  -----------------PLSAVPGGPHAVVPGVPN-----VPAAVPAPSVPS----VSTT 524
                             PL+  P  P + +P V N      P  +P P++ +    + T 
Sbjct: 1309 VKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTP 1368

Query: 525  SVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLA-PGTHSAPTSLPQSDLSQFQTQ 583
            ++  P +    + S ++S+  P +   +I   + +P + PG  S+P  +P S        
Sbjct: 1369 TLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNS-------- 1420

Query: 584  TQPLVGQVDDTRRKSEPLPQP-PLSLIAENKPVVKPPVADSLANPLQLTPMN-SLATSVF 641
              PL   V  T   S PL    P+S+          P+   ++ PL ++    +L TSV 
Sbjct: 1421 -SPLASPVSST--VSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVT 1477

Query: 642  SIAIPVDGDEDRNPSTA 658
                PV       PS A
Sbjct: 1478 PPLAPVVPAAPGPPSLA 1494



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 123/500 (24%), Positives = 185/500 (37%), Gaps = 105/500 (21%)

Query: 76   GDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPG 135
            G A +P  +  +  L   +++  + P +    +S  +   A AS       SAP   +  
Sbjct: 1409 GPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSAS 1468

Query: 136  GPQLAGSSAGP----VTAAPSQP---PTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYER 188
            GP L  S   P    V AAP  P   P+  S     + L   +                 
Sbjct: 1469 GPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAP--------------- 1513

Query: 189  DSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGG---SVVVVVASMQGAHGPESGTDSS 245
             S SS  T       H      T+    GL +T     S V+V AS   +  P +   + 
Sbjct: 1514 -SLSSSQTPG-----HPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAP 1567

Query: 246  LTAVSQLPPSEKMSQP--TPAQPQSF---SVGQPQPPPPPVGGAVAQSSAPLP---PFPG 297
              A S L P+   SQ   TP  P +    ++  P P PP          APLP   P PG
Sbjct: 1568 AQA-SLLAPASSASQALATPLAPMAAPQTAILAPSPAPP---------LAPLPVLAPSPG 1617

Query: 298  AATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQF 357
            AA    P++A++Q   P  A     + P T++  A P     P P P +   + Q     
Sbjct: 1618 AA----PVLASSQTPVPVMAP---SSTPGTSLASASPV----PAPTPVLAPSSTQTMLPA 1666

Query: 358  AYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQ 417
              P P       LP   S Q+  L          +PA   + G +   + + TL +GTG 
Sbjct: 1667 PVPSP-------LPSPASTQTLAL----------APALAPTLGGS---SPSQTLSLGTGN 1706

Query: 418  NASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQ 477
                   Q +  S  P+ ++ P   PAQ   +AP  P G P  T+     P L PA    
Sbjct: 1707 PQGPFPTQTL--SLTPASSLVPT--PAQTLSLAPGPPLG-PTQTLSLAPAPPLAPA---- 1757

Query: 478  PQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQ 537
                         P+   P     + P   +     PA SV +++ +   +P +    AQ
Sbjct: 1758 ------------SPVGPAPAHTLTLAPASSSASLLAPA-SVQTLTLSPAPVPTLGPAAAQ 1804

Query: 538  SQQL---SSHTPVSRSSSII 554
            +  L   S+ +P S++SS++
Sbjct: 1805 TLALAPASTQSPASQASSLV 1824



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 107/389 (27%), Positives = 135/389 (34%), Gaps = 69/389 (17%)

Query: 52   SRATDYGPEEVCERSSSEETLNN-VGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSA 110
            S  T   P  +   SS    LN+ V  A +P  V  + L     +A   APA    +  A
Sbjct: 1517 SSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPA 1576

Query: 111  RSVSGALASTLAAAATS-------------------APAPGAPGGPQLAGSSAGPVTAAP 151
             S S ALA+ LA  A                     AP+PGA   P LA S       AP
Sbjct: 1577 SSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGA--APVLASSQTPVPVMAP 1634

Query: 152  SQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIRHSSTFDQT 211
            S  P T  +    +        P               S  ++L         S    QT
Sbjct: 1635 SSTPGTSLASASPVPAPTPVLAP--------------SSTQTMLPAPVPSPLPSPASTQT 1680

Query: 212  AERDSGLGAT-GGSVVVVVASM--QGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQS 268
                  L  T GGS      S+      GP      SLT  S L        PTPAQ  S
Sbjct: 1681 LALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSL-------VPTPAQTLS 1733

Query: 269  FSVGQPQPPPPPVGGAVAQSSAPLPPF-PGAATGPQPMMAAAQPSQPQGAGPGGQTLPPT 327
             +      P PP+G     S AP PP  P +  GP P    A       A      L P 
Sbjct: 1734 LA------PGPPLGPTQTLSLAPAPPLAPASPVGPAP----AHTLTLAPASSSASLLAPA 1783

Query: 328  NVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHL--LPVQPSGQSEYLQQHV 385
            +V      ++L P P P +G PAA Q    A    Q P      L V  SG +      V
Sbjct: 1784 SV----QTLTLSPAPVPTLG-PAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMV 1838

Query: 386  AGLQPPSPAQPSS----TGAAASPATAAT 410
            + L P S  +P +    +G  + P+TA +
Sbjct: 1839 SRL-PVSKDEPDTLTLRSGPPSPPSTATS 1866



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 85/368 (23%), Positives = 128/368 (34%), Gaps = 71/368 (19%)

Query: 250  SQLPP-SEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPL----PPFPGAAT---- 300
            SQ+PP S     P PA         P   PPP    +   S+PL    P  P +A+    
Sbjct: 2489 SQIPPCSSPACTPPPA-----CTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNL 2543

Query: 301  --GPQP-----MMAAAQPSQPQGAGPGGQT------LPPTNVT--------LAQPAMSLP 339
              G +P       A A P   + A            +PP ++         +++  +SL 
Sbjct: 2544 PLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLT 2603

Query: 340  PQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYL-QQHVAGLQ-PPSPA--- 394
            P   P++   A   P       P    G  L V P G+   L      GL+ PPS A   
Sbjct: 2604 PS-APSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDE 2662

Query: 395  ---QPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAP 451
               +P      +   T A  P  + +    +    + A S  S A +   GP+      P
Sbjct: 2663 PLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPS------P 2716

Query: 452  CQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVP--------------- 496
             +P   P       V+  +   G G+P   P P++    P   V                
Sbjct: 2717 ARP---PRRRTSADVE--IRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQR 2771

Query: 497  GGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQH 556
            G    +VPGV    A+  +PSV S+S    + P +  P   +   S  TP  +     +H
Sbjct: 2772 GAASTLVPGVSETSASPGSPSVRSMSGPE-SSPPIGGPCEAAPSSSLPTPPQQPFIARRH 2830

Query: 557  VGLPLAPG 564
            + L +  G
Sbjct: 2831 IELGVTGG 2838



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 77/364 (21%), Positives = 131/364 (35%), Gaps = 47/364 (12%)

Query: 416  GQNASSVGAQ---LMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGP 472
            G  A + GA    ++ A    S    PR  PA+     P       PA+    + P L P
Sbjct: 2401 GARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAI-PALVP 2459

Query: 473  AGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVP 532
                 P S P P +    P++ +P         V  +P+  P   +P  S+ + T P   
Sbjct: 2460 V----PVSAPVP-ISAPNPITILP---------VHILPSPPPPSQIPPCSSPACTPPPAC 2505

Query: 533  APLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVD 592
             P        +HTP    + ++     PL  G  S P S   ++L          +G   
Sbjct: 2506 TPPP------AHTPPPAQTCLVTPSS-PLLLGPPSVPISASVTNLP---------LGLRP 2549

Query: 593  DTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDED 652
            +    ++ L  P    +A         VA S  + L L P   L      I    + +  
Sbjct: 2550 EAELCAQALASPESLELAS--------VASSETSSLSLVPPKDLLPVAVEILPVSEKNLS 2601

Query: 653  RNPS--TAFYQAFHLNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYAVREEVE 710
              PS  +   +A  +   +E ++  DSA G  +  +    E  + + +S+ +        
Sbjct: 2602 LTPSAPSLTLEAGSIPNGQEQEAP-DSAEGTTLTVLPEGEELPLCVSESNGLELPPSAAS 2660

Query: 711  VLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQPPQPTQ 770
               E ++E +E +   E         SS ++  +L T +    STS       + P P +
Sbjct: 2661 --DEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPAR 2718

Query: 771  PPQQ 774
            PP++
Sbjct: 2719 PPRR 2722



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 115/548 (20%), Positives = 184/548 (33%), Gaps = 88/548 (16%)

Query: 19   TAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATD-YGPEEVC---ERSSSEETLNN 74
            T++  T     T S + P E  T +V++     S  +   GP        R+S++  +  
Sbjct: 2673 TSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRG 2732

Query: 75   VGDAETPGTVSPNLL--LDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPG 132
             G         P +L  L G+L            V   R   GA ++ +   + ++ +PG
Sbjct: 2733 QGTGRPGQPPGPKVLRKLPGRLVTVVEEKEL---VRRRRQQRGAASTLVPGVSETSASPG 2789

Query: 133  APG-----GPQLAGSSAGPVTAAPSQ----PPTTCSSRFRVIKLD-HGSGEPYRRGRWTC 182
            +P      GP+ +    GP  AAPS     PP       R I+L   G G P        
Sbjct: 2790 SPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSP-------- 2841

Query: 183  MEYYERDSDSSVLTRSGDCIRHSSTFDQTAER---DSGLGATGGSVVVVVASMQGAHGPE 239
                  + D ++L  +   ++          R   D+G G       V  A      G  
Sbjct: 2842 -----ENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRG-------VDEAPSSTLKGKT 2889

Query: 240  SGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAA 299
            +G D                 P P  P++  V  P   P  + G       P P  P   
Sbjct: 2890 NGAD-----------------PVPG-PETLIVADPVLEPQLIPG-------PQPLGPQPV 2924

Query: 300  TGPQPMMAAAQPSQPQGAGPGGQTLP-PTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFA 358
              P P+++  +  + +G  P  + LP P  ++ A    S      P   +P    P    
Sbjct: 2925 HRPNPLLSPVE-KRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLV 2983

Query: 359  YPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQN 418
             P   +    +  V  S      ++      PPSP +PS        +T+     G G+ 
Sbjct: 2984 CPTATV-ANTVTTVTISTSPPKRKRGRPPKNPPSP-RPSQLPVLDRDSTSVLESCGLGRR 3041

Query: 419  ASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGG-----VVQPCLGPA 473
                G      SS   +   P T  A+       +  G+     GG     V+Q  L  A
Sbjct: 3042 RQPQGQGESEGSSSDEDGSRPLTRLAR----LRLEAEGMRGRKSGGSMVVAVIQDDLDLA 3097

Query: 474  GAGQ-PQSVPPPQMGGSGPLSAVPGGPHAVVP-----GVPNVPAAVPAPSVPSVSTTSVT 527
             +G     + PP +  +  L +    P ++VP      +P   A  P    P ++     
Sbjct: 3098 DSGPGGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPVGGSPGLAKRGRL 3157

Query: 528  MPNVPAPL 535
             P  P+PL
Sbjct: 3158 QP--PSPL 3163



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 78/347 (22%), Positives = 119/347 (34%), Gaps = 37/347 (10%)

Query: 232  MQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAP 291
            ++GA     G +   T V     +   + P    P    V +P P P P   +   +   
Sbjct: 2399 LRGARAETQGANH--TPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPA 2456

Query: 292  LPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMS-LPPQPGPAVGAPA 350
            L P P +A  P P+ A           P   T+ P ++  + P  S +PP   PA   P 
Sbjct: 2457 LVPVPVSA--PVPISA-----------PNPITILPVHILPSPPPPSQIPPCSSPACTPPP 2503

Query: 351  AQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPS-PAQPSSTGAAASPATAA 409
            A  P     P    PP     V PS  S  L      L PPS P   S T         A
Sbjct: 2504 ACTPP----PAHTPPPAQTCLVTPS--SPLL------LGPPSVPISASVTNLPLGLRPEA 2551

Query: 410  TLPVGTGQNASSVGAQLMGASSQPSEAMA-PRTGPAQGGQVAPCQPTGVPPATVGGVVQP 468
             L      +  S+    + +S   S ++  P+       ++ P     +        +  
Sbjct: 2552 ELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTL 2611

Query: 469  CLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTM 528
              G    GQ Q  P    G +  L+ +P G    +P   +    +  P  PS ++     
Sbjct: 2612 EAGSIPNGQEQEAPDSAEGTT--LTVLPEGEE--LPLCVSESNGLELP--PSAASDEPLQ 2665

Query: 529  PNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPL-APGTHSAPTSLPQ 574
              + A     +   + TP S      + V   + AP T S+ TS P+
Sbjct: 2666 EPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPE 2712



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 81/355 (22%), Positives = 117/355 (32%), Gaps = 62/355 (17%)

Query: 282  GGAVAQSS-APLPPFPGAATGPQPMMAAAQPSQPQGAG-----PGGQTLPPTNVTLAQPA 335
            GG   +S  A  P  PG     +   A A+    QGA         QT   T      PA
Sbjct: 2376 GGTHRRSKKAKAPERPGTRVSERLRGARAET---QGANHTPVISAHQTRSTTTPPRCSPA 2432

Query: 336  MSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ 395
                P+P P      A  P       P +P    +P+        L  H+    PP    
Sbjct: 2433 RERVPRPAPRPRPTPASAPAAIPALVP-VPVSAPVPISAPNPITILPVHILPSPPPPSQI 2491

Query: 396  PSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPT 455
            P  +  A +P  A T                      P  A  P   PAQ   V P  P 
Sbjct: 2492 PPCSSPACTPPPACT----------------------PPPAHTP--PPAQTCLVTPSSPL 2527

Query: 456  GVPPATV---GGVVQPCLG--PAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVP 510
             + P +V     V    LG  P      Q++  P+      +++      ++VP    +P
Sbjct: 2528 LLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLP 2587

Query: 511  AAVP-----------APSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGL 559
             AV             PS PS++  + ++PN      Q Q+       +  + + +   L
Sbjct: 2588 VAVEILPVSEKNLSLTPSAPSLTLEAGSIPN-----GQEQEAPDSAEGTTLTVLPEGEEL 2642

Query: 560  PLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKP 614
            PL   + S    LP S  S    Q +PL     +  R SE L +      +  KP
Sbjct: 2643 PLCV-SESNGLELPPSAASDEPLQ-EPL-----EADRTSEELTEAKTPTSSPEKP 2690



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 37/140 (26%)

Query: 458  PPATVGGV-VQPCLGPAGAGQPQSVPPPQ-MGGSGPLSAVPGGPHAVVPGVPNVPAAVPA 515
            P A +G V V+P  GP  + QP   P PQ +  S  +SA P GP  +    P  P  +P 
Sbjct: 1015 PRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPP 1074

Query: 516  ------------------------PSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSS 551
                                    P  P++S      P  PAP+  S       P   SS
Sbjct: 1075 LQPNSGSLPQVLPSPLGVLSGTSRPPTPTLS----LKPTPPAPVRLSP-----APPPGSS 1125

Query: 552  SIIQHVGLPLAPGTHSAPTS 571
            S+++ + +P  PG    P +
Sbjct: 1126 SLLKPLTVP--PGYTFPPAA 1143


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 104/405 (25%), Positives = 120/405 (29%), Gaps = 73/405 (18%)

Query: 254 PSEKMSQPTPAQPQSFSV--GQPQPP-----PPPVGGAVAQSSAPLPPFPGAATGPQPM- 305
           PS     P  A PQ  +   G P PP     PPP GG   Q     PP PG   GP P  
Sbjct: 29  PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP---PPPPGKPQGPPPQG 85

Query: 306 ----MAAAQPSQPQGAGPGGQ-----TLPPTNVTLAQPAMSLPPQ-PGPAVGAPAAQQPQ 355
                    P +PQG  P G        PP       P     PQ P P  G P    PQ
Sbjct: 86  GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 145

Query: 356 QFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGT 415
               PQ   PPG      P G ++         +P  P           P      P G 
Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP-----PPGK 200

Query: 416 GQNASSVGAQLMGASSQPSEAMAP---RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGP 472
            Q     G         P +   P       +Q  +  P +P G P             P
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP-------------P 247

Query: 473 AGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVP 532
            G  QPQ  PPP           PG P    P   N P   P P            P  P
Sbjct: 248 QGGNQPQGPPPP-----------PGKPQGPPPQGGNKPQGPPPPG----------KPQGP 286

Query: 533 APLAQSQQLSSHTPVSRSSSI-----IQHVGLPLAPGTHSAPT----SLPQSDLSQFQTQ 583
            P   S+  SS +P  +          Q  G P  PG    P     + PQ      + Q
Sbjct: 287 PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 346

Query: 584 TQPLVGQVDDTRRKSEP-LPQPPLSLIAENKPVVKPPVADSLANP 627
             P  G       +S P  PQ P      N     PP   +   P
Sbjct: 347 GPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 84/275 (30%), Positives = 92/275 (33%), Gaps = 52/275 (18%)

Query: 238 PESGTDSSLTAVSQLPPSEKMSQPTPA--QPQSFSVGQPQPP-----PPPVGGAVAQSSA 290
           P  G + S +  S+ PP +    P     QPQ    G P PP     PPP GG   Q   
Sbjct: 163 PPQGDNKSRS--SRSPPGKPQGPPPQGGNQPQ----GPPPPPGKPQGPPPQGGNKPQG-- 214

Query: 291 PLPPFPGAATGPQPM------MAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGP 344
             PP PG   GP P        A + P +PQG  P G   P             PP PG 
Sbjct: 215 --PPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP----------QGPPPPPGK 262

Query: 345 AVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHV-----------AGLQPPSP 393
             G P    PQ    PQ   PPG      P G S+                  G QP  P
Sbjct: 263 PQGPP----PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP 318

Query: 394 AQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ 453
             P        P      P G        G    G S   S A +P   P    Q     
Sbjct: 319 PPPPGK-PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS-ARSPPGKPQGPPQQEGNN 376

Query: 454 PTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGG 488
           P G PP   G   QP   P  AGQPQ  P P  GG
Sbjct: 377 PQGPPPPAGGNPQQPQAPP--AGQPQGPPRPPQGG 409



 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 88/289 (30%), Positives = 103/289 (35%), Gaps = 52/289 (17%)

Query: 253 PPSEKMSQPTPAQPQSFSV----GQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAA 308
           PP +    P     +S S     G+PQ PPP  G    Q   P PP PG   GP P    
Sbjct: 155 PPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN---QPQGPPPP-PGKPQGPPPQGG- 209

Query: 309 AQPSQPQGAGPGG--QTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPP 366
              ++PQG  P G  Q  PP     +Q A S P       G P    PQ    PQ   PP
Sbjct: 210 ---NKPQGPPPPGKPQGPPPQGDNKSQSARSPP-------GKPQGPPPQGGNQPQGPPPP 259

Query: 367 GHLLPVQPSGQSEYLQQHVAGLQPPS-PAQPSSTGAAASPATAATLPVGTGQNASSVGA- 424
               P +P G          G  PP  P  P   G + S ++ +  P G  Q     G  
Sbjct: 260 ----PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS--PPGKPQGPPPQGGN 313

Query: 425 QLMGASSQPSEAMAPRTGPAQGGQVA-----PCQPTGVPPATVGGVVQPCLGPAGA--GQ 477
           Q  G    P +   P   P QGG        P +P G PP   G   +    P G   G 
Sbjct: 314 QPQGPPPPPGKPQGP---PPQGGNKPQGPPPPGKPQGPPPQG-GSKSRSARSPPGKPQGP 369

Query: 478 PQSV------PPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPS 520
           PQ        PPP  GG+      P  P A   G P  P   P    PS
Sbjct: 370 PQQEGNNPQGPPPPAGGN------PQQPQAPPAGQPQGPPRPPQGGRPS 412



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 58/200 (29%), Positives = 70/200 (35%), Gaps = 42/200 (21%)

Query: 238 PESGTDSSLTAVSQLPPSEKMSQPTPA--QPQSFSVGQPQPP-----PPPVGGAVAQSSA 290
           P  G + S +A S  PP +    P     QPQ    G P PP     PPP GG   Q   
Sbjct: 225 PPQGDNKSQSARS--PPGKPQGPPPQGGNQPQ----GPPPPPGKPQGPPPQGGNKPQG-- 276

Query: 291 PLPPFPGAATGPQPM------MAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPG- 343
             PP PG   GP P        + + P +PQG  P G   P             PPQ G 
Sbjct: 277 --PPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 334

Query: 344 -----PAVGAPAAQQPQQFAYPQ--------PQIPPGH-----LLPVQPSGQSEYLQQHV 385
                P  G P    PQ  +  +        PQ PP         P  P+G +    Q  
Sbjct: 335 KPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP 394

Query: 386 AGLQPPSPAQPSSTGAAASP 405
              QP  P +P   G  + P
Sbjct: 395 PAGQPQGPPRPPQGGRPSRP 414


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 76.6 bits (187), Expect = 8e-14
 Identities = 116/491 (23%), Positives = 172/491 (35%), Gaps = 31/491 (6%)

Query: 264 AQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQT 323
           AQ Q+     P PPP  V         P PPF G   GP P      P  P G  P    
Sbjct: 22  AQQQALRFRGPAPPPNAVMRGPPPLMRPPPPF-GMMRGPPP-----PPRPPFGRPPFDPN 75

Query: 324 LPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP---QIPPGHLLPVQPSGQSEY 380
           +PP    +  P    PP   P +  P    P   + P P     PPG + PV   G    
Sbjct: 76  MPP----MPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPG-MPPVTAPGTPAL 130

Query: 381 LQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQ-PSEAMAP 439
                  ++  +P        A +  +A T P G      S    ++ A +Q  ++A A 
Sbjct: 131 PPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQ 190

Query: 440 RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSA-VPGG 498
               AQ    A  Q      A      Q         Q Q+    Q      + A V   
Sbjct: 191 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQ 250

Query: 499 PHAVVPGVPNVPAAVPAPSV---PSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQ 555
             A   G      + PAP+V    S ST S T        + +Q +S+ T   ++ S   
Sbjct: 251 VQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAV 310

Query: 556 HVGLPLAPGTHSAPTSLPQSDLSQFQTQTQP-----LVGQVDDTRRKSEPLPQPPLSLIA 610
            V  P    +  APT+ P   + Q   QT P      V Q         P+  PP  +  
Sbjct: 311 SVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPL 370

Query: 611 ENKPVVKPPVADSLANPL--QLTPMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTL 668
              P+  P V   +A P+   + P  ++A S  ++A      E     TA  + ++ N  
Sbjct: 371 PGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNN- 429

Query: 669 KESKSLWDSASG-GGVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELVE---RNS 724
           +  +S W+          ++ KI++ +       +    EE +  +E IKE+ E      
Sbjct: 430 RTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEE 489

Query: 725 LLERENALLKS 735
           + E E A  K+
Sbjct: 490 MTEEEKAAQKA 500



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 61/272 (22%), Positives = 94/272 (34%), Gaps = 33/272 (12%)

Query: 84  VSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGGPQLAGSS 143
           ++P L    Q+ A A A A       A++ + A A   A A   A A         A + 
Sbjct: 173 LTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 232

Query: 144 AGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIR 203
           A     A +Q      ++ +   +  G+  P                     T S     
Sbjct: 233 AQAQAQAQAQVQAQVQAQVQAQAV--GASTP--------------------TTSSPAPAV 270

Query: 204 HSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTP 263
            +ST   T    +    T  SV   V++      P +   +  +AVS   P+  +S P P
Sbjct: 271 STSTSSSTPSSTTSTTTTATSVAQTVST------PTTQDQTPSSAVSVATPTVSVSTPAP 324

Query: 264 AQPQSFSVGQPQPP--PPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGG 321
                 +V QP P   PP V  +V Q +  +P FP     P  +     P    G  PG 
Sbjct: 325 TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPG- 383

Query: 322 QTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQ 353
             + P  V +  P +++   P    GA A  +
Sbjct: 384 --MAPPIVPMIHPQVAIAASPATLAGATAVSE 413


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 123/533 (23%), Positives = 171/533 (32%), Gaps = 78/533 (14%)

Query: 71  TLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAAT---- 126
           ++++ G +  P T  P   + G    +A  PAN   V        AL     A+A+    
Sbjct: 261 SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL 320

Query: 127 -SAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEY 185
            + P PG    P   G   G +   P + PT   S   +      +  P  R        
Sbjct: 321 GAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR-------- 372

Query: 186 YERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSS 245
                             +SS+   +A   S   ++  S     AS      P S    +
Sbjct: 373 ----------------FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPT 416

Query: 246 LTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSA---PLPPFPGAATGP 302
             +VS  PP  K +Q  P+ P      Q  PPPPP G  +A S+A   P PP  GA +  
Sbjct: 417 SLSVSNQPP--KYTQ--PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472

Query: 303 QPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP 362
            P ++       Q      Q              S PP PG A   P        A+P  
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG-AFPHPLEGGSSHHAHPYA 531

Query: 363 QIP-----------PGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSST------------ 399
             P           P HL P  P  Q  Y Q    G    S +  SS+            
Sbjct: 532 MSPSLGSLRPYPPGPAHLPP--PHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS 589

Query: 400 ---GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTG 456
              G   +P     +P  T  +A+        ASS      A   GP   G+ AP     
Sbjct: 590 PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP----- 644

Query: 457 VPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAP 516
             P        P   P      ++  PP   G+ P    P GP    PG P V    P P
Sbjct: 645 -SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSP----PAGPGTFKPGSPTVG---PGP 696

Query: 517 SVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAP 569
             P+  +   ++P  PA  A    LS+       +   +    P+ P    +P
Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 93/329 (28%), Positives = 118/329 (35%), Gaps = 50/329 (15%)

Query: 334 PAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPP-GHLLPVQPSGQSEYLQQHVAGLQPPS 392
           P    PP P P    P  +QP+    P P + P G+  P++P     +  Q   G  PP 
Sbjct: 161 PPPLFPPSPQPPDSTP--RQPEASFEPHPSVTPTGYHAPMEPPTSRMF--QAPPGAPPPH 216

Query: 393 PA-QPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQP--------------SEAM 437
           P   P  TG   S       P G G  ASSVG    G    P              +   
Sbjct: 217 PQLYPGGTGGVLSGPPMG--PKGGGA-ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT 273

Query: 438 APRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQP---QSVPPPQMGGSGPLSA 494
            P T P  GG +    P+  PPA    V  P L P  A +P    S  PP +G   PL  
Sbjct: 274 KPPTTPVGGGNL----PSAPPPANFPHVT-PNLPPPPALRPLNNASASPPGLGAQ-PLPG 327

Query: 495 VPGGPHAV-------VPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPV 547
               PHA+        PG    P   P+P     +++S   P +  P + S   S+    
Sbjct: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASS 387

Query: 548 SRSSSIIQHVGLPLAPGTHSAPTSLPQ----SDLSQFQTQTQPLVGQVDDTRRKSEPLPQ 603
           S SSS       P +    S P S P     S  +Q    TQP +           P P 
Sbjct: 388 SSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL--PSQAVWSQGPPPP 445

Query: 604 PPLSLIAENK---PVVKPPV--ADSLANP 627
           PP   +  N    P   PP   A S A+P
Sbjct: 446 PPYGRLLANSNAHPGPFPPSTGAQSTAHP 474



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 107/416 (25%), Positives = 136/416 (32%), Gaps = 58/416 (13%)

Query: 253 PPSEKMSQPTPAQPQSFSVGQPQ--------PPPPPVGGAVAQSSA----------PLPP 294
           PP+ +M Q  P  P       P         PP  P GG  A S            P  P
Sbjct: 200 PPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTP 259

Query: 295 FPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQP 354
              +++G         P+ P G G      PP N     P +  PP   P   A +A  P
Sbjct: 260 ISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNA-SASPP 318

Query: 355 QQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ-------PSSTGAAASPAT 407
              A P     PGHL      GQ       + GL PP P +       P S   A+S A 
Sbjct: 319 GLGAQPL----PGHLPSPHAMGQG------MGGL-PPGPEKGPTLAPSPHSLPPASSSAP 367

Query: 408 AATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQ 467
           A  +      ++SS  A    +SS  S A      P    Q  P  P   PP T   V  
Sbjct: 368 APPMRFPYSSSSSSSAAASSSSSSSSSSA-----SPFPASQALPSYPHSFPPPTSLSVSN 422

Query: 468 PCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVT 527
               P    QP S+P   +   GP    P  P+  +    N   A P P  PS    S  
Sbjct: 423 Q---PPKYTQP-SLPSQAVWSQGP---PPPPPYGRLLANSN---AHPGPFPPSTGAQSTA 472

Query: 528 MPNVPA--PLAQSQQLSSHTPVSRSSSIIQHVGL--PLAPGTHSAPTSLPQSDLSQFQTQ 583
            P V       Q QQ        +     QH G   P  PG    P     S  +     
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAM 532

Query: 584 TQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATS 639
           + P +G +         LP PP S ++ ++     P   S +N    T   S   S
Sbjct: 533 S-PSLGSLRPYPPGPAHLP-PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCS 586



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 98/380 (25%), Positives = 133/380 (35%), Gaps = 56/380 (14%)

Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFS----VGQP--QPPPPPVGGAVAQSSA 290
           GP  G      A S   P+     P P  P S S     G P  +PP  PVGG    S+ 
Sbjct: 230 GPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAP 289

Query: 291 PLPPFPGAATG--PQPMMAAAQPSQPQGAGPGGQTLP---PTNVTLAQPAMSLPPQPGPA 345
           P   FP       P P +     +     G G Q LP   P+   + Q    LP  PGP 
Sbjct: 290 PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--PGPE 347

Query: 346 VGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASP 405
            G   A  P         +PP       P  +  Y     +     S +  SS+ A+  P
Sbjct: 348 KGPTLAPSPH-------SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400

Query: 406 ATAA------TLPVGTGQNASSVGAQLMGAS--SQPSEAMAPRTGPAQGGQVA--PCQPT 455
           A+ A      + P  T  + S+   +    S  SQ   +  P   P  G  +A     P 
Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG 460

Query: 456 GVPPATVGGVVQPCLGPAGA---------------GQPQSVPPPQMGGSGPLSAVPGG-P 499
             PP+T  G       P                   Q Q       G SGP    PG  P
Sbjct: 461 PFPPST--GAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP--PPPGAFP 516

Query: 500 HAVVPGVPN--VPAAVPAPSVPSVSTTSVTMPNVPAPLAQ---SQQLSSHTPVSRSSSII 554
           H +  G  +   P A+ +PS+ S+        ++P P +Q   SQ   +  PVS SS+  
Sbjct: 517 HPLEGGSSHHAHPYAM-SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSS 575

Query: 555 QHVGLPLAPGTHSAPTSLPQ 574
                   P +H +P+  PQ
Sbjct: 576 SSTSQGSYPCSHPSPSQGPQ 595



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 72/273 (26%), Positives = 97/273 (35%), Gaps = 68/273 (24%)

Query: 384 HVAGLQPPSPAQPSST----GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAP 439
           H   L PPSP  P ST     A+  P  + T    TG +A             P E    
Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVT---PTGYHA-------------PMEPPTS 203

Query: 440 RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSV---------PPP----QM 486
           R   A  G   P  P   P  T G +  P +GP G G   SV         PPP     +
Sbjct: 204 RMFQAPPG-APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISV 262

Query: 487 GGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTP 546
             SG   A P  P     G  N+P+A P  + P V+      PN+P P A         P
Sbjct: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVT------PNLPPPPAL-------RP 309

Query: 547 VSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPL 606
           ++ +S+    +G    PG   +P ++ Q             +G +     K   L   P 
Sbjct: 310 LNNASASPPGLGAQPLPGHLPSPHAMGQG------------MGGLPPGPEKGPTLAPSPH 357

Query: 607 SLIAENKPVVKPPVADSLANPLQLTPMNSLATS 639
           SL         PP + S   P    P +S ++S
Sbjct: 358 SL---------PPASSSAPAPPMRFPYSSSSSS 381



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 101/422 (23%), Positives = 131/422 (31%), Gaps = 96/422 (22%)

Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFP 296
           GPE G   + +  S LPP+   S   PA P  F              + + SS+   PFP
Sbjct: 345 GPEKGPTLAPSPHS-LPPA---SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400

Query: 297 GAA-------TGPQPMMAA--------AQPSQPQGA--GPGGQTLPPTNVTLAQPAMSLP 339
            +        + P P   +         QPS P  A    G    PP    LA       
Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG 460

Query: 340 PQPGPAVGAPAA------------QQPQQFAYPQPQ--------------IPPGHLLPVQ 373
           P P P+ GA +             QQ QQ    Q Q               PPG      
Sbjct: 461 PFP-PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519

Query: 374 PSGQSEYLQQHVAGLQ-------PPSPAQ--PSSTGAAASPATAATLPVGTGQNASSVGA 424
             G S +   +            PP PA   P  +  + S A     PV +  N+SS  +
Sbjct: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579

Query: 425 QLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGG------VVQPCLGPAGAGQP 478
           Q     S PS        P+QG Q AP     VP  T         +      PAG    
Sbjct: 580 QGSYPCSHPS--------PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTA 631

Query: 479 QSVPPPQMGGSGPLSAV----------PGGPHAVVPGVPNVPAAVPAPSVP-SVSTTSVT 527
               PP  G   P              PG P +   G P        P+ P +    S T
Sbjct: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT 691

Query: 528 MPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAP--GTHSAPTSLPQSDLSQFQTQTQ 585
           +   P P A    L S  P             P AP  G   + T + Q    +++T   
Sbjct: 692 VGPGPLPPAGPSGLPSLPPP------------PAAPASGPPLSATQIKQEPAEEYETPES 739

Query: 586 PL 587
           P+
Sbjct: 740 PV 741


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 123/533 (23%), Positives = 171/533 (32%), Gaps = 78/533 (14%)

Query: 71  TLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAAT---- 126
           ++++ G +  P T  P   + G    +A  PAN   V        AL     A+A+    
Sbjct: 261 SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL 320

Query: 127 -SAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEY 185
            + P PG    P   G   G +   P + PT   S   +      +  P  R        
Sbjct: 321 GAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR-------- 372

Query: 186 YERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSS 245
                             +SS+   +A   S   ++  S     AS      P S    +
Sbjct: 373 ----------------FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPT 416

Query: 246 LTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSA---PLPPFPGAATGP 302
             +VS  PP  K +Q  P+ P      Q  PPPPP G  +A S+A   P PP  GA +  
Sbjct: 417 SLSVSNQPP--KYTQ--PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472

Query: 303 QPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP 362
            P ++       Q      Q              S PP PG A   P        A+P  
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG-AFPHPLEGGSSHHAHPYA 531

Query: 363 QIP-----------PGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSST------------ 399
             P           P HL P  P  Q  Y Q    G    S +  SS+            
Sbjct: 532 MSPSLGSLRPYPPGPAHLPP--PHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS 589

Query: 400 ---GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTG 456
              G   +P     +P  T  +A+        ASS      A   GP   G+ AP     
Sbjct: 590 PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP----- 644

Query: 457 VPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAP 516
             P        P   P      ++  PP   G+ P    P GP    PG P V    P P
Sbjct: 645 -SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSP----PAGPGTFKPGSPTVG---PGP 696

Query: 517 SVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAP 569
             P+  +   ++P  PA  A    LS+       +   +    P+ P    +P
Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 93/329 (28%), Positives = 118/329 (35%), Gaps = 50/329 (15%)

Query: 334 PAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPP-GHLLPVQPSGQSEYLQQHVAGLQPPS 392
           P    PP P P    P  +QP+    P P + P G+  P++P     +  Q   G  PP 
Sbjct: 161 PPPLFPPSPQPPDSTP--RQPEASFEPHPSVTPTGYHAPMEPPTSRMF--QAPPGAPPPH 216

Query: 393 PA-QPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQP--------------SEAM 437
           P   P  TG   S       P G G  ASSVG    G    P              +   
Sbjct: 217 PQLYPGGTGGVLSGPPMG--PKGGGA-ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT 273

Query: 438 APRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQP---QSVPPPQMGGSGPLSA 494
            P T P  GG +    P+  PPA    V  P L P  A +P    S  PP +G   PL  
Sbjct: 274 KPPTTPVGGGNL----PSAPPPANFPHVT-PNLPPPPALRPLNNASASPPGLGAQ-PLPG 327

Query: 495 VPGGPHAV-------VPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPV 547
               PHA+        PG    P   P+P     +++S   P +  P + S   S+    
Sbjct: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASS 387

Query: 548 SRSSSIIQHVGLPLAPGTHSAPTSLPQ----SDLSQFQTQTQPLVGQVDDTRRKSEPLPQ 603
           S SSS       P +    S P S P     S  +Q    TQP +           P P 
Sbjct: 388 SSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL--PSQAVWSQGPPPP 445

Query: 604 PPLSLIAENK---PVVKPPV--ADSLANP 627
           PP   +  N    P   PP   A S A+P
Sbjct: 446 PPYGRLLANSNAHPGPFPPSTGAQSTAHP 474



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 107/416 (25%), Positives = 136/416 (32%), Gaps = 58/416 (13%)

Query: 253 PPSEKMSQPTPAQPQSFSVGQPQ--------PPPPPVGGAVAQSSA----------PLPP 294
           PP+ +M Q  P  P       P         PP  P GG  A S            P  P
Sbjct: 200 PPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTP 259

Query: 295 FPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQP 354
              +++G         P+ P G G      PP N     P +  PP   P   A +A  P
Sbjct: 260 ISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNA-SASPP 318

Query: 355 QQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ-------PSSTGAAASPAT 407
              A P     PGHL      GQ       + GL PP P +       P S   A+S A 
Sbjct: 319 GLGAQPL----PGHLPSPHAMGQG------MGGL-PPGPEKGPTLAPSPHSLPPASSSAP 367

Query: 408 AATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQ 467
           A  +      ++SS  A    +SS  S A      P    Q  P  P   PP T   V  
Sbjct: 368 APPMRFPYSSSSSSSAAASSSSSSSSSSA-----SPFPASQALPSYPHSFPPPTSLSVSN 422

Query: 468 PCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVT 527
               P    QP S+P   +   GP    P  P+  +    N   A P P  PS    S  
Sbjct: 423 Q---PPKYTQP-SLPSQAVWSQGP---PPPPPYGRLLANSN---AHPGPFPPSTGAQSTA 472

Query: 528 MPNVPA--PLAQSQQLSSHTPVSRSSSIIQHVGL--PLAPGTHSAPTSLPQSDLSQFQTQ 583
            P V       Q QQ        +     QH G   P  PG    P     S  +     
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAM 532

Query: 584 TQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATS 639
           + P +G +         LP PP S ++ ++     P   S +N    T   S   S
Sbjct: 533 S-PSLGSLRPYPPGPAHLP-PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCS 586



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 98/380 (25%), Positives = 133/380 (35%), Gaps = 56/380 (14%)

Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFS----VGQP--QPPPPPVGGAVAQSSA 290
           GP  G      A S   P+     P P  P S S     G P  +PP  PVGG    S+ 
Sbjct: 230 GPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAP 289

Query: 291 PLPPFPGAATG--PQPMMAAAQPSQPQGAGPGGQTLP---PTNVTLAQPAMSLPPQPGPA 345
           P   FP       P P +     +     G G Q LP   P+   + Q    LP  PGP 
Sbjct: 290 PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--PGPE 347

Query: 346 VGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASP 405
            G   A  P         +PP       P  +  Y     +     S +  SS+ A+  P
Sbjct: 348 KGPTLAPSPH-------SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400

Query: 406 ATAA------TLPVGTGQNASSVGAQLMGAS--SQPSEAMAPRTGPAQGGQVA--PCQPT 455
           A+ A      + P  T  + S+   +    S  SQ   +  P   P  G  +A     P 
Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG 460

Query: 456 GVPPATVGGVVQPCLGPAGA---------------GQPQSVPPPQMGGSGPLSAVPGG-P 499
             PP+T  G       P                   Q Q       G SGP    PG  P
Sbjct: 461 PFPPST--GAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP--PPPGAFP 516

Query: 500 HAVVPGVPN--VPAAVPAPSVPSVSTTSVTMPNVPAPLAQ---SQQLSSHTPVSRSSSII 554
           H +  G  +   P A+ +PS+ S+        ++P P +Q   SQ   +  PVS SS+  
Sbjct: 517 HPLEGGSSHHAHPYAM-SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSS 575

Query: 555 QHVGLPLAPGTHSAPTSLPQ 574
                   P +H +P+  PQ
Sbjct: 576 SSTSQGSYPCSHPSPSQGPQ 595



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 72/273 (26%), Positives = 97/273 (35%), Gaps = 68/273 (24%)

Query: 384 HVAGLQPPSPAQPSST----GAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAP 439
           H   L PPSP  P ST     A+  P  + T    TG +A             P E    
Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVT---PTGYHA-------------PMEPPTS 203

Query: 440 RTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSV---------PPP----QM 486
           R   A  G   P  P   P  T G +  P +GP G G   SV         PPP     +
Sbjct: 204 RMFQAPPG-APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISV 262

Query: 487 GGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTP 546
             SG   A P  P     G  N+P+A P  + P V+      PN+P P A         P
Sbjct: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVT------PNLPPPPAL-------RP 309

Query: 547 VSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPL 606
           ++ +S+    +G    PG   +P ++ Q             +G +     K   L   P 
Sbjct: 310 LNNASASPPGLGAQPLPGHLPSPHAMGQG------------MGGLPPGPEKGPTLAPSPH 357

Query: 607 SLIAENKPVVKPPVADSLANPLQLTPMNSLATS 639
           SL         PP + S   P    P +S ++S
Sbjct: 358 SL---------PPASSSAPAPPMRFPYSSSSSS 381



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 101/422 (23%), Positives = 131/422 (31%), Gaps = 96/422 (22%)

Query: 237 GPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFP 296
           GPE G   + +  S LPP+   S   PA P  F              + + SS+   PFP
Sbjct: 345 GPEKGPTLAPSPHS-LPPA---SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400

Query: 297 GAA-------TGPQPMMAA--------AQPSQPQGA--GPGGQTLPPTNVTLAQPAMSLP 339
            +        + P P   +         QPS P  A    G    PP    LA       
Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG 460

Query: 340 PQPGPAVGAPAA------------QQPQQFAYPQPQ--------------IPPGHLLPVQ 373
           P P P+ GA +             QQ QQ    Q Q               PPG      
Sbjct: 461 PFP-PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519

Query: 374 PSGQSEYLQQHVAGLQ-------PPSPAQ--PSSTGAAASPATAATLPVGTGQNASSVGA 424
             G S +   +            PP PA   P  +  + S A     PV +  N+SS  +
Sbjct: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579

Query: 425 QLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGG------VVQPCLGPAGAGQP 478
           Q     S PS        P+QG Q AP     VP  T         +      PAG    
Sbjct: 580 QGSYPCSHPS--------PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTA 631

Query: 479 QSVPPPQMGGSGPLSAV----------PGGPHAVVPGVPNVPAAVPAPSVP-SVSTTSVT 527
               PP  G   P              PG P +   G P        P+ P +    S T
Sbjct: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT 691

Query: 528 MPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAP--GTHSAPTSLPQSDLSQFQTQTQ 585
           +   P P A    L S  P             P AP  G   + T + Q    +++T   
Sbjct: 692 VGPGPLPPAGPSGLPSLPPP------------PAAPASGPPLSATQIKQEPAEEYETPES 739

Query: 586 PL 587
           P+
Sbjct: 740 PV 741


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 139/611 (22%), Positives = 205/611 (33%), Gaps = 130/611 (21%)

Query: 249  VSQLPPSEKMSQPTPAQPQSFSVGQPQPPPP--PVGGAVAQSSAPLPPF----------- 295
            V Q PP      P P  PQ      P PPPP  P   A A  S+P PPF           
Sbjct: 753  VPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSP-PPFIATQVPVLEPQ 811

Query: 296  -PGAATGP-----QPMMAAAQPS-QPQGAGPGGQTLPP-------------TNVTLAQP- 334
             PG+   P     QP++   QP   P    P   + PP              N    QP 
Sbjct: 812  LPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPS 871

Query: 335  -----AMSLPPQPG-PAVGAPAAQQPQQFAYPQPQIPPGHLL-------PVQPSGQSEYL 381
                 A +LPP+P  P   +PA  Q      P    PP  LL       P   S Q +  
Sbjct: 872  RPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLY 931

Query: 382  QQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRT 441
             Q +  +QPP+P  PS    +  P      P  + Q       Q +     P     P+ 
Sbjct: 932  LQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQ-------QQLQQQPPPPPPPQPQP 984

Query: 442  GPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHA 501
             P Q  Q  P +P  + P      +Q    P G   P   PPP   G  P    P  P  
Sbjct: 985  PPQQQHQPPP-RPVHLQPMQFSTHIQQPPPPQGQQPPH--PPP---GQQPPPPQPAKPQQ 1038

Query: 502  VV------------PGVPNVPAAVPAP---------SVPSVSTTSVTMPNV--------- 531
            V+            P         P+P            S++  S    NV         
Sbjct: 1039 VIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRA 1098

Query: 532  -----PAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQP 586
                 P PL   ++   H+P+ RS         P +P     P   P+S  +      +P
Sbjct: 1099 ASVVQPQPLVVVKEEKIHSPIIRSE--------PFSPSLRPEPPKHPESIKAPVHLPQRP 1150

Query: 587  LVGQVDDTRRKSEPLPQ--PPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIA 644
             +  VD  R    P  Q  PP     ++K   +P    +    L++  M S A+ V    
Sbjct: 1151 EMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLV---- 1206

Query: 645  IPVDGDEDRNPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDNKIEQAMDLVKSHLMYA 704
                    ++P+T        +T K S   ++            + E+    +K+   +A
Sbjct: 1207 -------QKHPTTP------SSTAKSSSDSFEQFRRAA-----REKEEREKALKAQAEHA 1248

Query: 705  VREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQANPGSTSQQQAVIAQ 764
             +E+  + +E+++   + ++L +   A  ++    +Q  Q   +Q       QQ A +A 
Sbjct: 1249 EKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQ--QRQEQQQQQQQQAAAVAA 1306

Query: 765  PPQPTQPPQQP 775
               P     QP
Sbjct: 1307 AATPQAQSSQP 1317



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 103/414 (24%), Positives = 140/414 (33%), Gaps = 73/414 (17%)

Query: 256  EKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQ 315
            ++M Q     PQ       QPPPPP      Q   P PP                PS PQ
Sbjct: 744  QQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPP----------------PSMPQ 787

Query: 316  GAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAY-PQPQIPPGHLLPVQP 374
             A P  ++ PP  +    P   L PQ   +V  P     Q   + PQP++PP HL     
Sbjct: 788  QAAPAMKSSPPPFIATQVPV--LEPQLPGSVFDPIGHFTQPILHLPQPELPP-HLPQPPE 844

Query: 375  SGQSEYLQQHVAGLQPPS--------PAQPSSTGAAASPATAATLPVGTGQN-------- 418
                 +L QH A + PP+        P++PS+  AA  P  A    V             
Sbjct: 845  HSTPPHLNQH-AVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQP 903

Query: 419  ----------------ASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATV 462
                            A  + +  M    Q  + + P T      +V    P  +PP   
Sbjct: 904  PMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH 963

Query: 463  GGVVQPC-LGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGV--PNVPAAVPAPSVP 519
              V Q     P     PQ  PPPQ     P   V   P      +  P  P     P  P
Sbjct: 964  PSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPP 1023

Query: 520  SVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQ 579
                     P  P  + Q      H+P    S       L  AP    +P  +    +SQ
Sbjct: 1024 PGQQPPPPQPAKPQQVIQHH----HSPRHHKSDPYSTGHLREAP----SPLMIHSPQMSQ 1075

Query: 580  FQTQTQPLVGQVDDTRRKSE----PLPQP-PLSLIAENK---PVVK-PPVADSL 624
            FQ+ T     Q +   +K E     + QP PL ++ E K   P+++  P + SL
Sbjct: 1076 FQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSL 1129



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 52/195 (26%), Positives = 75/195 (38%), Gaps = 47/195 (24%)

Query: 225 VVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGA 284
           +++V A  +G    E+GT  +   VS +P + + S  TP Q Q+     PQP PPPV   
Sbjct: 171 IMIVQAKGRGRGRKETGT--AKPGVSTVPNTTQAS--TPPQTQT-----PQPNPPPVQAT 221

Query: 285 V------------------------AQSSAPLPPFPGA--ATGPQPMMA-----AAQPSQ 313
                                     Q+  P+PP P    A  PQP+ +     AA P Q
Sbjct: 222 PHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATP-Q 280

Query: 314 P----QGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPG-- 367
           P    +G      T  PT +       SLPP+P         +  +    P+  +P    
Sbjct: 281 PVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQ 340

Query: 368 HLLPVQPSGQSEYLQ 382
           H  P + S  SE L+
Sbjct: 341 HPAPEKSSKVSEQLK 355



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 42/184 (22%), Positives = 60/184 (32%), Gaps = 28/184 (15%)

Query: 414 GTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPA 473
           G G+     G    G S+ P+   A      Q  Q  P      PP      VQ    P 
Sbjct: 178 GRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNP------PP------VQATPHPF 225

Query: 474 GAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPA 533
            A  P  +    +     ++ VP  P    P VP  P   PAP+   V +    +   P 
Sbjct: 226 PAVTPDLIVQTPV-----MTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQ 280

Query: 534 PLAQS---QQLSSHTPVSRSSSIIQHVGLPLAPGT--------HSAPTSLPQSDLSQFQT 582
           P+      ++ +  T  +    I +   LP  P T         S P   P+ D+   Q 
Sbjct: 281 PVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQ 340

Query: 583 QTQP 586
              P
Sbjct: 341 HPAP 344


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 94/323 (29%), Positives = 116/323 (35%), Gaps = 61/323 (18%)

Query: 254 PSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGP-QPMMAAAQPS 312
           P  + SQP PA+P +    QP     P+         P+ P PG    P QP+  A  P+
Sbjct: 319 PGHEKSQPGPAKPPA----QPSGLTKPLAQQPGTVKPPVQP-PGTTKPPAQPLGPAKPPA 373

Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPV 372
           Q  G+       P     LAQP         P VG   AQQP     P  Q+     L  
Sbjct: 374 QQTGSEKPSSEQPGPK-ALAQP---------PGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423

Query: 373 QPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQ 432
           QP  QS       A    P+       G    PA  A    G G+ +    AQ  G +  
Sbjct: 424 QPGLQSP------AKAPGPTKTPVQQPGPGKIPAQQA----GPGKTS----AQQTGPTKP 469

Query: 433 PSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPL 492
           PS+   P   P Q  Q  P +P   PP   G    P   P       + PPPQ  G    
Sbjct: 470 PSQLPGPAKPPPQ--QPGPAKP---PPQQPGSAKPPSQQPG-----STKPPPQQPG---- 515

Query: 493 SAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSS 552
              P  P    PG    P+  P  + PS           P+P   S Q S+  PVS++ S
Sbjct: 516 ---PAKPSPQQPGSTKPPSQQPGSAKPSAQQ--------PSPAKPSAQQST-KPVSQTGS 563

Query: 553 IIQHVGLPLAPGTHSAPTSLPQS 575
                G PL P T S     P S
Sbjct: 564 -----GKPLQPPTVSPSAKQPPS 581



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 114/486 (23%), Positives = 156/486 (32%), Gaps = 90/486 (18%)

Query: 229 VASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQS 288
           +A   G   P      + T V Q  P +  +Q   A P   S  Q  P  PP    +   
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ--AGPGKTSAQQTGPTKPP--SQLPGP 476

Query: 289 SAPLPPFPGAATGPQPMMAAAQP--SQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAV 346
           + P P  PG A  P     +A+P   QP    P  Q   P   +  QP  + PP   P  
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536

Query: 347 GAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHV---AGLQPPSPAQPSSTGAAA 403
             P+AQQP   A P  Q       PV  +G  + LQ      +  QPPS   P  T    
Sbjct: 537 AKPSAQQPSP-AKPSAQ---QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP-KTICPL 591

Query: 404 SPATAATLPV------GTGQNASSVGAQLMGASSQPS-------EAMAPRTGPAQGGQVA 450
              T   L V       T     +    L G +  P          +  +   A GG +A
Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651

Query: 451 PCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPP-------------PQMGGSGPLSAVP- 496
           P   +  P      V         + QPQ   P             P+     PL   P 
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711

Query: 497 --GGPHAVVPGVPNV-----PAAVPAPSVPS-------------------------VSTT 524
             G P A     P       PA    PSVPS                          S++
Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS 771

Query: 525 SVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLA--------------PGTHSAPT 570
           + T P++P+   QSQ     TP  ++ S       P                P + S   
Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831

Query: 571 SLP-QSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQ 629
           S P  S  S+ Q Q  P+  + +  + +++  P+P    + +  P   PP     A    
Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT--PPGPRPTAGQTV 889

Query: 630 LTPMNS 635
            TP  S
Sbjct: 890 PTPQQS 895



 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 112/463 (24%), Positives = 156/463 (33%), Gaps = 59/463 (12%)

Query: 230 ASMQGAHGPESGTDSSLTAVSQLPPSEKM--SQPTPAQPQSFSVGQPQPPPPPVGGAVAQ 287
           A   G+  P S       A++Q P   K    QP PA+P +  VG P+P     G    Q
Sbjct: 373 AQQTGSEKPSSEQPGP-KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG---LQ 428

Query: 288 SSAPLP-PFPGAATGPQPMMAAAQPSQP--QGAGPGGQTLPPTNVTLAQPAMSLPPQPGP 344
           S A  P P       P P    AQ + P    A   G T PP+   L  PA   P QPGP
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ--LPGPAKPPPQQPGP 486

Query: 345 AV--------GAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQP 396
           A           P +QQP     P  Q  P    P QP       QQ   G   PS  QP
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ--PGSAKPSAQQP 544

Query: 397 SSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRT--------------- 441
           S    +A  +T      G+G+        +  ++ QP     P+T               
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQP--PTVSPSAKQPPSQGLPKTICPLCNTTELLLHVP 602

Query: 442 GPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHA 501
             A       CQ T    +  G    P L         +    +  G G L+ VP  P  
Sbjct: 603 EKANFNTCTECQTTVC--SLCGFNPNPHLTEVKEWLCLNCQMKRALG-GDLAPVPSSPQP 659

Query: 502 VVPGVPNVPAAVPAPSVPSVSTTS-------------VTMPNVPAPLAQSQQL-SSHTPV 547
            +   P    +  + S P    TS                P  P PL +   L  S +  
Sbjct: 660 KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAK 719

Query: 548 SRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPL- 606
           ++       +  P  P   S P+   ++ ++  + +   +V    D    S    +P + 
Sbjct: 720 AKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIP 779

Query: 607 --SLIAENKPVVKPPVADSLANPLQLTPMNSLATSVF-SIAIP 646
              + ++ +    PP+    A P Q  P      S F S AIP
Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 92/388 (23%), Positives = 128/388 (32%), Gaps = 55/388 (14%)

Query: 284  AVAQSSAPLP--PFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQ 341
            A+    AP+P  P P   T P    +A   S PQ      QT P  +   A P   L   
Sbjct: 645  ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ----QTSPKKD---AAPKQDLSKA 697

Query: 342  PGPAVGAPAAQQPQQFAYPQP---QIPPGHLL-----PVQPSGQSEYLQQHVAGLQPPSP 393
            P P    P  +QP     P     Q P    L     P +PS  SE  +  VA  +P  P
Sbjct: 698  PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP 757

Query: 394  AQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ 453
                 T    S ++A T P        S   +      +   A   ++ P  G +V+P  
Sbjct: 758  KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD 817

Query: 454  PTGVPPATVGGVVQPCLGPAGAGQPQ-SVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAA 512
               +P       +    GP+   + Q  V P Q       +     P      +P     
Sbjct: 818  SKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT 877

Query: 513  VPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSH-------------TP------------- 546
             P P  P+   T  T    P P  QS++ S +             TP             
Sbjct: 878  PPGPR-PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936

Query: 547  --VSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQP 604
               S++S++I   G    PG HS   S P + + Q    +QP   Q         P P P
Sbjct: 937  SIFSQASNLISTAG---QPGPHS--QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP-PAP 990

Query: 605  PLSLIAENKPVVKPPVADSLANPLQLTP 632
              S+    K   K P A+ L    +  P
Sbjct: 991  AKSIPV--KKETKAPAAEKLEPKAEQAP 1016



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 88/377 (23%), Positives = 124/377 (32%), Gaps = 50/377 (13%)

Query: 250  SQLPPSEKMSQPTPAQPQSFS-------VGQPQPPPPPVGGAVAQSSAPLPPFPGAATGP 302
            SQLP         PA+P+ F          QP PPPPP          P PP P     P
Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP---------PPPPPPPPPPPPP 2424

Query: 303  QPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP 362
             P+        P    P    LP   +T+A P  +  P              +    P  
Sbjct: 2425 PPL--------PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT 2476

Query: 363  QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSV 422
            +I      PV P   S  +   +     P P++P        P    T    T  +    
Sbjct: 2477 RICTTAPPPVPPKPSS--IPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPT 2534

Query: 423  GAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVP--PATVGGVVQPCLGPAGAGQPQS 480
            G  L  + +      A    P+    ++P      P    ++         P+  G P  
Sbjct: 2535 GLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTD 2594

Query: 481  VPPPQMGGSGPLSAVPGGPHAVVPGVPNVP--AAVPAP-----------SVPSVSTTSVT 527
                Q   S PL +      +V P    VP   AV  P           ++ + S T VT
Sbjct: 2595 SSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVT 2654

Query: 528  MPN--VPAPLAQSQQLS---SHTPVSRSSSIIQHVGL-PLAPGTHSAPTSLPQSDLSQFQ 581
             P+    AP + +Q L+   S T VS + S    VGL  ++      P +L    L + Q
Sbjct: 2655 APSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQ 2714

Query: 582  TQTQ---PLVGQVDDTR 595
             +      LVG V D R
Sbjct: 2715 YKEDGKLQLVGDVIDLR 2731



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 25/180 (13%)

Query: 241 GTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAAT 300
           G  S      Q+ P +K  +P  AQ +     +P   P P G       +P PP      
Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMPKG-------SPTPP------ 879

Query: 301 GPQPMMAAAQPSQPQGAGPGGQT----LPPTNVTLAQPAMSLPPQP---GPAVGAPAAQQ 353
           GP+P      P+  Q   P  Q+    L   ++T A  +    PQ    G   G  A+  
Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939

Query: 354 PQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPV 413
            Q          PG   P   SG    ++Q  A  QPP+   P  +   A PA A ++PV
Sbjct: 940 SQASNLISTAGQPG---PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996



 Score = 33.9 bits (76), Expect = 0.60
 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 5/37 (13%)

Query: 744 QLPTQQANPGSTSQQQAVIAQPPQ-----PTQPPQQP 775
           ++P QQA PG TS QQ    +PP         PPQQP
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 94/323 (29%), Positives = 116/323 (35%), Gaps = 61/323 (18%)

Query: 254 PSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGP-QPMMAAAQPS 312
           P  + SQP PA+P +    QP     P+         P+ P PG    P QP+  A  P+
Sbjct: 319 PGHEKSQPGPAKPPA----QPSGLTKPLAQQPGTVKPPVQP-PGTTKPPAQPLGPAKPPA 373

Query: 313 QPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPV 372
           Q  G+       P     LAQP         P VG   AQQP     P  Q+     L  
Sbjct: 374 QQTGSEKPSSEQPGPK-ALAQP---------PGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423

Query: 373 QPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQ 432
           QP  QS       A    P+       G    PA  A    G G+ +    AQ  G +  
Sbjct: 424 QPGLQSP------AKAPGPTKTPVQQPGPGKIPAQQA----GPGKTS----AQQTGPTKP 469

Query: 433 PSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPL 492
           PS+   P   P Q  Q  P +P   PP   G    P   P       + PPPQ  G    
Sbjct: 470 PSQLPGPAKPPPQ--QPGPAKP---PPQQPGSAKPPSQQPG-----STKPPPQQPG---- 515

Query: 493 SAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSS 552
              P  P    PG    P+  P  + PS           P+P   S Q S+  PVS++ S
Sbjct: 516 ---PAKPSPQQPGSTKPPSQQPGSAKPSAQQ--------PSPAKPSAQQST-KPVSQTGS 563

Query: 553 IIQHVGLPLAPGTHSAPTSLPQS 575
                G PL P T S     P S
Sbjct: 564 -----GKPLQPPTVSPSAKQPPS 581



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 114/486 (23%), Positives = 156/486 (32%), Gaps = 90/486 (18%)

Query: 229 VASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQS 288
           +A   G   P      + T V Q  P +  +Q   A P   S  Q  P  PP    +   
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ--AGPGKTSAQQTGPTKPP--SQLPGP 476

Query: 289 SAPLPPFPGAATGPQPMMAAAQP--SQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAV 346
           + P P  PG A  P     +A+P   QP    P  Q   P   +  QP  + PP   P  
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536

Query: 347 GAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHV---AGLQPPSPAQPSSTGAAA 403
             P+AQQP   A P  Q       PV  +G  + LQ      +  QPPS   P  T    
Sbjct: 537 AKPSAQQPSP-AKPSAQ---QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP-KTICPL 591

Query: 404 SPATAATLPV------GTGQNASSVGAQLMGASSQPS-------EAMAPRTGPAQGGQVA 450
              T   L V       T     +    L G +  P          +  +   A GG +A
Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651

Query: 451 PCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPP-------------PQMGGSGPLSAVP- 496
           P   +  P      V         + QPQ   P             P+     PL   P 
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711

Query: 497 --GGPHAVVPGVPNV-----PAAVPAPSVPS-------------------------VSTT 524
             G P A     P       PA    PSVPS                          S++
Sbjct: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS 771

Query: 525 SVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLA--------------PGTHSAPT 570
           + T P++P+   QSQ     TP  ++ S       P                P + S   
Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831

Query: 571 SLP-QSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQ 629
           S P  S  S+ Q Q  P+  + +  + +++  P+P    + +  P   PP     A    
Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT--PPGPRPTAGQTV 889

Query: 630 LTPMNS 635
            TP  S
Sbjct: 890 PTPQQS 895



 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 112/463 (24%), Positives = 156/463 (33%), Gaps = 59/463 (12%)

Query: 230 ASMQGAHGPESGTDSSLTAVSQLPPSEKM--SQPTPAQPQSFSVGQPQPPPPPVGGAVAQ 287
           A   G+  P S       A++Q P   K    QP PA+P +  VG P+P     G    Q
Sbjct: 373 AQQTGSEKPSSEQPGP-KALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG---LQ 428

Query: 288 SSAPLP-PFPGAATGPQPMMAAAQPSQP--QGAGPGGQTLPPTNVTLAQPAMSLPPQPGP 344
           S A  P P       P P    AQ + P    A   G T PP+   L  PA   P QPGP
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ--LPGPAKPPPQQPGP 486

Query: 345 AV--------GAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQP 396
           A           P +QQP     P  Q  P    P QP       QQ   G   PS  QP
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ--PGSAKPSAQQP 544

Query: 397 SSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRT--------------- 441
           S    +A  +T      G+G+        +  ++ QP     P+T               
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQP--PTVSPSAKQPPSQGLPKTICPLCNTTELLLHVP 602

Query: 442 GPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHA 501
             A       CQ T    +  G    P L         +    +  G G L+ VP  P  
Sbjct: 603 EKANFNTCTECQTTVC--SLCGFNPNPHLTEVKEWLCLNCQMKRALG-GDLAPVPSSPQP 659

Query: 502 VVPGVPNVPAAVPAPSVPSVSTTS-------------VTMPNVPAPLAQSQQL-SSHTPV 547
            +   P    +  + S P    TS                P  P PL +   L  S +  
Sbjct: 660 KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAK 719

Query: 548 SRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPL- 606
           ++       +  P  P   S P+   ++ ++  + +   +V    D    S    +P + 
Sbjct: 720 AKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIP 779

Query: 607 --SLIAENKPVVKPPVADSLANPLQLTPMNSLATSVF-SIAIP 646
              + ++ +    PP+    A P Q  P      S F S AIP
Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 92/388 (23%), Positives = 128/388 (32%), Gaps = 55/388 (14%)

Query: 284  AVAQSSAPLP--PFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQ 341
            A+    AP+P  P P   T P    +A   S PQ      QT P  +   A P   L   
Sbjct: 645  ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ----QTSPKKD---AAPKQDLSKA 697

Query: 342  PGPAVGAPAAQQPQQFAYPQP---QIPPGHLL-----PVQPSGQSEYLQQHVAGLQPPSP 393
            P P    P  +QP     P     Q P    L     P +PS  SE  +  VA  +P  P
Sbjct: 698  PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP 757

Query: 394  AQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ 453
                 T    S ++A T P        S   +      +   A   ++ P  G +V+P  
Sbjct: 758  KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFD 817

Query: 454  PTGVPPATVGGVVQPCLGPAGAGQPQ-SVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAA 512
               +P       +    GP+   + Q  V P Q       +     P      +P     
Sbjct: 818  SKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT 877

Query: 513  VPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSH-------------TP------------- 546
             P P  P+   T  T    P P  QS++ S +             TP             
Sbjct: 878  PPGPR-PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936

Query: 547  --VSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQP 604
               S++S++I   G    PG HS   S P + + Q    +QP   Q         P P P
Sbjct: 937  SIFSQASNLISTAG---QPGPHS--QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP-PAP 990

Query: 605  PLSLIAENKPVVKPPVADSLANPLQLTP 632
              S+    K   K P A+ L    +  P
Sbjct: 991  AKSIPV--KKETKAPAAEKLEPKAEQAP 1016



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 88/377 (23%), Positives = 124/377 (32%), Gaps = 50/377 (13%)

Query: 250  SQLPPSEKMSQPTPAQPQSFS-------VGQPQPPPPPVGGAVAQSSAPLPPFPGAATGP 302
            SQLP         PA+P+ F          QP PPPPP          P PP P     P
Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP---------PPPPPPPPPPPPP 2424

Query: 303  QPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP 362
             P+        P    P    LP   +T+A P  +  P              +    P  
Sbjct: 2425 PPL--------PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT 2476

Query: 363  QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSV 422
            +I      PV P   S  +   +     P P++P        P    T    T  +    
Sbjct: 2477 RICTTAPPPVPPKPSS--IPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPT 2534

Query: 423  GAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVP--PATVGGVVQPCLGPAGAGQPQS 480
            G  L  + +      A    P+    ++P      P    ++         P+  G P  
Sbjct: 2535 GLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTD 2594

Query: 481  VPPPQMGGSGPLSAVPGGPHAVVPGVPNVP--AAVPAP-----------SVPSVSTTSVT 527
                Q   S PL +      +V P    VP   AV  P           ++ + S T VT
Sbjct: 2595 SSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVT 2654

Query: 528  MPN--VPAPLAQSQQLS---SHTPVSRSSSIIQHVGL-PLAPGTHSAPTSLPQSDLSQFQ 581
             P+    AP + +Q L+   S T VS + S    VGL  ++      P +L    L + Q
Sbjct: 2655 APSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQ 2714

Query: 582  TQTQ---PLVGQVDDTR 595
             +      LVG V D R
Sbjct: 2715 YKEDGKLQLVGDVIDLR 2731



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 25/180 (13%)

Query: 241 GTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAAT 300
           G  S      Q+ P +K  +P  AQ +     +P   P P G       +P PP      
Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMPKG-------SPTPP------ 879

Query: 301 GPQPMMAAAQPSQPQGAGPGGQT----LPPTNVTLAQPAMSLPPQP---GPAVGAPAAQQ 353
           GP+P      P+  Q   P  Q+    L   ++T A  +    PQ    G   G  A+  
Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939

Query: 354 PQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPV 413
            Q          PG   P   SG    ++Q  A  QPP+   P  +   A PA A ++PV
Sbjct: 940 SQASNLISTAGQPG---PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996



 Score = 33.9 bits (76), Expect = 0.60
 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 5/37 (13%)

Query: 744 QLPTQQANPGSTSQQQAVIAQPPQ-----PTQPPQQP 775
           ++P QQA PG TS QQ    +PP         PPQQP
Sbjct: 448 KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 154/603 (25%), Positives = 201/603 (33%), Gaps = 108/603 (17%)

Query: 187 ERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSL 246
           E  SD   + +       S    Q  E DS   A    +     ++Q   G      S+ 
Sbjct: 142 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 201

Query: 247 TAVSQLPPSEKMSQPTPAQPQ-----SFSVGQPQPPPPPVGGAVAQSSAPL--------- 292
               QLP        T   PQ     S +  QPQ P  PV     Q +  L         
Sbjct: 202 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 261

Query: 293 -PPFPGAATGPQPMMAAA-QPSQPQGAGPG--GQTLPPTNVTLAQPAMSLPPQPGPAVGA 348
            PP P      QP+  +A QPS P  A P   GQ  P  +   A P +  P  P P    
Sbjct: 262 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 321

Query: 349 PAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ--------PSSTG 400
           P A Q Q      P     H     P+ QS    Q     QP  PA         P +T 
Sbjct: 322 PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 381

Query: 401 AAASPATAATL--PVGTGQNASSVGAQL-----MGASSQPSEAMAPRTGPAQGGQVAPCQ 453
               PA  A    P  +G +  S+ A L     +   S  S    P   P     +   Q
Sbjct: 382 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 441

Query: 454 PTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGG--SGPLSAVPGGPHAVVPGVPNVPA 511
           P    PA           P G  Q Q++PPP      +G     P  P A  P VP  P 
Sbjct: 442 PLPSSPAQ----------PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 491

Query: 512 AVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTS 571
            +  P+ PS ST     P  P   AQ        P S         G   + G+ +  +S
Sbjct: 492 PITPPTCPSTSTP----PAGPGTSAQP-------PCS---------GAAASGGSIAGGSS 531

Query: 572 LPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLT 631
            P   L   Q + + L    DD      P P PP S      P  +P V D        T
Sbjct: 532 CP---LPTVQIKEEAL----DDAEEPESP-PPPPRS------PSPEPTVVD--------T 569

Query: 632 PMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDNKIE 691
           P ++  ++ F   +      DR  ++      +   L  SK             +  K E
Sbjct: 570 PSHASQSARFYKHL------DRGYNSCARTDLYFMPLAGSK-------------LAKKRE 610

Query: 692 QAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQ-A 750
           +A++  K       REE E  KE+ KE  ER    ERE       SS+    +L   Q +
Sbjct: 611 EAIEKAKREAEQKAREEREREKEKEKER-EREREREREAERAAKASSSAHEGRLSDPQLS 669

Query: 751 NPG 753
            PG
Sbjct: 670 GPG 672



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 125/569 (21%), Positives = 188/569 (33%), Gaps = 82/569 (14%)

Query: 2   SKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDES-RTEDVSSEIFDVSRATDYGPE 60
           SK    KKS  ++    ++ + ++  +  +   D +E+ RT    ++  ++SR     P 
Sbjct: 70  SKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PS 127

Query: 61  EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST 120
           E    SS   ++N+ G ++       N      + +     ++       + +     + 
Sbjct: 128 EGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAL 187

Query: 121 LA-AAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGR 179
            A    T AP+   PG PQL   + GP  +A + PP    +          S  P +   
Sbjct: 188 QAPTGVTPAPSSAPPGTPQL--PTPGPTPSATAVPPQGSPT---------ASQAPNQPQA 236

Query: 180 WTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPE 239
            T    +     +  L        H             L  + G       +    HG  
Sbjct: 237 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG-- 294

Query: 240 SGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQP---PPPPVGGAVAQSSAPLPPFP 296
                      Q PP     Q   A P     G PQP   PP    G     ++P   +P
Sbjct: 295 -----------QGPPGPHSLQ---AGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340

Query: 297 GAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQ 356
             +       +A Q  QP    P  Q LPP    LA P +  PP                
Sbjct: 341 HTSLQLPASQSALQSQQP----PREQPLPP--APLAMPHIKPPPTT-------------- 380

Query: 357 FAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLP---V 413
              PQ   P  H  P   SG S +     A L PP   +P S+ +   P +A   P   +
Sbjct: 381 -PIPQLPAPQAHKHPPHLSGPSPFSMN--ANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 437

Query: 414 GTGQNASSVGAQLMGASSQPSEAMAPRTGPAQG-GQVA--------PCQPTGVPPATVGG 464
              Q   S  AQ  G +   +    P + P  G  QVA        P  P G PP T   
Sbjct: 438 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT 497

Query: 465 VVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGV---------PNVPAAVPA 515
                  PAG G   S  PP  G +    ++ GG    +P V            P + P 
Sbjct: 498 CPSTSTPPAGPG--TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP 555

Query: 516 PSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544
           P  P   +   T+ + P+  +QS +   H
Sbjct: 556 P--PRSPSPEPTVVDTPSHASQSARFYKH 582


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 154/603 (25%), Positives = 201/603 (33%), Gaps = 108/603 (17%)

Query: 187  ERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSL 246
            E  SD   + +       S    Q  E DS   A    +     ++Q   G      S+ 
Sbjct: 696  EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755

Query: 247  TAVSQLPPSEKMSQPTPAQPQ-----SFSVGQPQPPPPPVGGAVAQSSAPL--------- 292
                QLP        T   PQ     S +  QPQ P  PV     Q +  L         
Sbjct: 756  PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815

Query: 293  -PPFPGAATGPQPMMAAA-QPSQPQGAGPG--GQTLPPTNVTLAQPAMSLPPQPGPAVGA 348
             PP P      QP+  +A QPS P  A P   GQ  P  +   A P +  P  P P    
Sbjct: 816  PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 875

Query: 349  PAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ--------PSSTG 400
            P A Q Q      P     H     P+ QS    Q     QP  PA         P +T 
Sbjct: 876  PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935

Query: 401  AAASPATAATL--PVGTGQNASSVGAQL-----MGASSQPSEAMAPRTGPAQGGQVAPCQ 453
                PA  A    P  +G +  S+ A L     +   S  S    P   P     +   Q
Sbjct: 936  IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995

Query: 454  PTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGG--SGPLSAVPGGPHAVVPGVPNVPA 511
            P    PA           P G  Q Q++PPP      +G     P  P A  P VP  P 
Sbjct: 996  PLPSSPAQ----------PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045

Query: 512  AVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTS 571
             +  P+ PS ST     P  P   AQ        P S         G   + G+ +  +S
Sbjct: 1046 PITPPTCPSTSTP----PAGPGTSAQP-------PCS---------GAAASGGSIAGGSS 1085

Query: 572  LPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLT 631
             P   L   Q + + L    DD      P P PP S      P  +P V D        T
Sbjct: 1086 CP---LPTVQIKEEAL----DDAEEPESP-PPPPRS------PSPEPTVVD--------T 1123

Query: 632  PMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDNKIE 691
            P ++  ++ F   +      DR  ++      +   L  SK             +  K E
Sbjct: 1124 PSHASQSARFYKHL------DRGYNSCARTDLYFMPLAGSK-------------LAKKRE 1164

Query: 692  QAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQ-A 750
            +A++  K       REE E  KE+ KE  ER    ERE       SS+    +L   Q +
Sbjct: 1165 EAIEKAKREAEQKAREEREREKEKEKER-EREREREREAERAAKASSSAHEGRLSDPQLS 1223

Query: 751  NPG 753
             PG
Sbjct: 1224 GPG 1226



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 125/569 (21%), Positives = 188/569 (33%), Gaps = 82/569 (14%)

Query: 2    SKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDES-RTEDVSSEIFDVSRATDYGPE 60
            SK    KKS  ++    ++ + ++  +  +   D +E+ RT    ++  ++SR     P 
Sbjct: 624  SKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PS 681

Query: 61   EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST 120
            E    SS   ++N+ G ++       N      + +     ++       + +     + 
Sbjct: 682  EGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAL 741

Query: 121  LA-AAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGR 179
             A    T AP+   PG PQL   + GP  +A + PP    +          S  P +   
Sbjct: 742  QAPTGVTPAPSSAPPGTPQL--PTPGPTPSATAVPPQGSPT---------ASQAPNQPQA 790

Query: 180  WTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPE 239
             T    +     +  L        H             L  + G       +    HG  
Sbjct: 791  PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG-- 848

Query: 240  SGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQP---PPPPVGGAVAQSSAPLPPFP 296
                       Q PP     Q   A P     G PQP   PP    G     ++P   +P
Sbjct: 849  -----------QGPPGPHSLQ---AGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894

Query: 297  GAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQ 356
              +       +A Q  QP    P  Q LPP    LA P +  PP                
Sbjct: 895  HTSLQLPASQSALQSQQP----PREQPLPP--APLAMPHIKPPPTT-------------- 934

Query: 357  FAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLP---V 413
               PQ   P  H  P   SG S +     A L PP   +P S+ +   P +A   P   +
Sbjct: 935  -PIPQLPAPQAHKHPPHLSGPSPFSMN--ANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991

Query: 414  GTGQNASSVGAQLMGASSQPSEAMAPRTGPAQG-GQVA--------PCQPTGVPPATVGG 464
               Q   S  AQ  G +   +    P + P  G  QVA        P  P G PP T   
Sbjct: 992  PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT 1051

Query: 465  VVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGV---------PNVPAAVPA 515
                   PAG G   S  PP  G +    ++ GG    +P V            P + P 
Sbjct: 1052 CPSTSTPPAGPG--TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP 1109

Query: 516  PSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544
            P  P   +   T+ + P+  +QS +   H
Sbjct: 1110 P--PRSPSPEPTVVDTPSHASQSARFYKH 1136


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 154/603 (25%), Positives = 201/603 (33%), Gaps = 108/603 (17%)

Query: 187  ERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSL 246
            E  SD   + +       S    Q  E DS   A    +     ++Q   G      S+ 
Sbjct: 696  EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755

Query: 247  TAVSQLPPSEKMSQPTPAQPQ-----SFSVGQPQPPPPPVGGAVAQSSAPL--------- 292
                QLP        T   PQ     S +  QPQ P  PV     Q +  L         
Sbjct: 756  PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815

Query: 293  -PPFPGAATGPQPMMAAA-QPSQPQGAGPG--GQTLPPTNVTLAQPAMSLPPQPGPAVGA 348
             PP P      QP+  +A QPS P  A P   GQ  P  +   A P +  P  P P    
Sbjct: 816  PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLP 875

Query: 349  PAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQ--------PSSTG 400
            P A Q Q      P     H     P+ QS    Q     QP  PA         P +T 
Sbjct: 876  PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935

Query: 401  AAASPATAATL--PVGTGQNASSVGAQL-----MGASSQPSEAMAPRTGPAQGGQVAPCQ 453
                PA  A    P  +G +  S+ A L     +   S  S    P   P     +   Q
Sbjct: 936  IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995

Query: 454  PTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGG--SGPLSAVPGGPHAVVPGVPNVPA 511
            P    PA           P G  Q Q++PPP      +G     P  P A  P VP  P 
Sbjct: 996  PLPSSPAQ----------PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045

Query: 512  AVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTS 571
             +  P+ PS ST     P  P   AQ        P S         G   + G+ +  +S
Sbjct: 1046 PITPPTCPSTSTP----PAGPGTSAQP-------PCS---------GAAASGGSIAGGSS 1085

Query: 572  LPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLT 631
             P   L   Q + + L    DD      P P PP S      P  +P V D        T
Sbjct: 1086 CP---LPTVQIKEEAL----DDAEEPESP-PPPPRS------PSPEPTVVD--------T 1123

Query: 632  PMNSLATSVFSIAIPVDGDEDRNPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDNKIE 691
            P ++  ++ F   +      DR  ++      +   L  SK             +  K E
Sbjct: 1124 PSHASQSARFYKHL------DRGYNSCARTDLYFMPLAGSK-------------LAKKRE 1164

Query: 692  QAMDLVKSHLMYAVREEVEVLKEQIKELVERNSLLERENALLKSLSSNDQLSQLPTQQ-A 750
            +A++  K       REE E  KE+ KE  ER    ERE       SS+    +L   Q +
Sbjct: 1165 EAIEKAKREAEQKAREEREREKEKEKER-EREREREREAERAAKASSSAHEGRLSDPQLS 1223

Query: 751  NPG 753
             PG
Sbjct: 1224 GPG 1226



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 125/569 (21%), Positives = 188/569 (33%), Gaps = 82/569 (14%)

Query: 2    SKMPAKKKSCFQITSVTTAQVATSITEDTESLDDPDES-RTEDVSSEIFDVSRATDYGPE 60
            SK    KKS  ++    ++ + ++  +  +   D +E+ RT    ++  ++SR     P 
Sbjct: 624  SKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS--PS 681

Query: 61   EVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALAST 120
            E    SS   ++N+ G ++       N      + +     ++       + +     + 
Sbjct: 682  EGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAL 741

Query: 121  LA-AAATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGR 179
             A    T AP+   PG PQL   + GP  +A + PP    +          S  P +   
Sbjct: 742  QAPTGVTPAPSSAPPGTPQL--PTPGPTPSATAVPPQGSPT---------ASQAPNQPQA 790

Query: 180  WTCMEYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPE 239
             T    +     +  L        H             L  + G       +    HG  
Sbjct: 791  PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG-- 848

Query: 240  SGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQP---PPPPVGGAVAQSSAPLPPFP 296
                       Q PP     Q   A P     G PQP   PP    G     ++P   +P
Sbjct: 849  -----------QGPPGPHSLQ---AGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894

Query: 297  GAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQ 356
              +       +A Q  QP    P  Q LPP    LA P +  PP                
Sbjct: 895  HTSLQLPASQSALQSQQP----PREQPLPP--APLAMPHIKPPPTT-------------- 934

Query: 357  FAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLP---V 413
               PQ   P  H  P   SG S +     A L PP   +P S+ +   P +A   P   +
Sbjct: 935  -PIPQLPAPQAHKHPPHLSGPSPFSMN--ANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991

Query: 414  GTGQNASSVGAQLMGASSQPSEAMAPRTGPAQG-GQVA--------PCQPTGVPPATVGG 464
               Q   S  AQ  G +   +    P + P  G  QVA        P  P G PP T   
Sbjct: 992  PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT 1051

Query: 465  VVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGV---------PNVPAAVPA 515
                   PAG G   S  PP  G +    ++ GG    +P V            P + P 
Sbjct: 1052 CPSTSTPPAGPG--TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP 1109

Query: 516  PSVPSVSTTSVTMPNVPAPLAQSQQLSSH 544
            P  P   +   T+ + P+  +QS +   H
Sbjct: 1110 P--PRSPSPEPTVVDTPSHASQSARFYKH 1136


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 115/423 (27%), Positives = 148/423 (34%), Gaps = 53/423 (12%)

Query: 230  ASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQ---PQSFSVGQPQPPPPPVGGAVA 286
            ++     G    +DS  +  S +  S   + P+PAQ       S G   P   P  GA  
Sbjct: 614  STFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQ 673

Query: 287  QSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAV 346
            Q +A     PG   G  P  A     Q     P     P        P  S P   GP  
Sbjct: 674  QPTAA----PGLPVGSVPAPACPPSLQQHFPDPAMSFAP------VLPPPSTPMPTGPGQ 723

Query: 347  GAPAAQQPQQFAYPQP---QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAA 403
             AP  QQP   A P P    + P  ++P+QP      +  H+    PP  A  S  GA A
Sbjct: 724  PAPPGQQPPPLAQPTPLPQVLAPQPVVPLQP------VPPHL----PPYLAPASQVGAPA 773

Query: 404  SPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVG 463
                   +P    Q  + V  Q+      P   + P   P  G    P     +P ATV 
Sbjct: 774  Q-LKPLQMPQAPLQPLAQVPPQM------PPIPVVPPITPLAGIDGLPPALPDLPTATVP 826

Query: 464  GVVQP-CLGPAGAGQPQSVPPPQMGGSGPLSAV-----PGGPHAVV--PGVPNVPAAVP- 514
             V  P    PA      + P P    + PL AV     PG P A+     VPN PA +P 
Sbjct: 827  PVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPL 886

Query: 515  -APSVPSVSTTSV-----TMPNVPA-PLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHS 567
             A + P V+  S+      +P  P  P A  Q   +  P S   ++      P  P    
Sbjct: 887  LAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPP 946

Query: 568  APTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKP-PVADSLAN 626
             PT  PQ  L    T     V     TR     LP  P+      +PV+ P P       
Sbjct: 947  QPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPM---LPPQPVLPPQPALPVRPE 1003

Query: 627  PLQ 629
            PLQ
Sbjct: 1004 PLQ 1006



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 92/352 (26%), Positives = 122/352 (34%), Gaps = 36/352 (10%)

Query: 238  PESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQP----PPPPVGGAVAQSSAPLP 293
            P +G D    A+  LP +   + P    PQ FS     P    P PP   A+   +  LP
Sbjct: 806  PLAGIDGLPPALPDLPTA---TVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLP 862

Query: 294  PFPGA------------ATGPQPMMAAAQPS------QPQGAGPGGQTLPPTNVTLAQPA 335
              PGA            A    P++A A P           A   GQ + P       P 
Sbjct: 863  HPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPT 922

Query: 336  MSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPS--GQSEYLQQHVAGLQPPSP 393
              +PP P   V    A  PQ    PQP +PP  +LP QP+   Q     Q     QP  P
Sbjct: 923  -DVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLP 981

Query: 394  AQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ 453
             QP        P   A LPV        +  Q   A++  S+ +     P      A   
Sbjct: 982  PQPMLPPQPVLPPQPA-LPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVP 1040

Query: 454  PTGVPPATVGGVVQP-CLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAA 512
               VPPA V     P  L PA        P      S  + +VP     ++P     PA 
Sbjct: 1041 TVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLP-----PAN 1095

Query: 513  VPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPG 564
             P P  P +++   T+     P+ Q +Q S   P     S   + G  +  G
Sbjct: 1096 PPLPGGPGIASPCPTVQLTVEPV-QEEQASQDKPPGLPQSCESYGGSDVTSG 1146



 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 95/354 (26%), Positives = 121/354 (34%), Gaps = 47/354 (13%)

Query: 244  SSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAP--LPPFPGAATG 301
            S + A +QL P +    P     Q      P P  PP+         P  LP  P A   
Sbjct: 767  SQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVP 826

Query: 302  PQPMMAAAQPSQ--PQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAY 359
            P P      P+   P  A P    LPP +  L   A+ LP  PG    AP A   +    
Sbjct: 827  PVPPPQYFSPAVILPSLAAP----LPPASPALPLQAVKLPHPPG----APLAMPCRTIVP 878

Query: 360  PQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNA 419
              P   P  LL V P G +           P  P  P++    A P      P  T QN 
Sbjct: 879  NAPATIP--LLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMA-PTDVPPSPHHTVQNM 935

Query: 420  SSVGAQ--LMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQ 477
             +   Q  L    + P + + P         V P QPT  P        QP L P     
Sbjct: 936  RATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPP--------QPVLPPQPMLP 987

Query: 478  PQSVPPPQMGGSGPLSAVPGGPH-------AVVPG-----------VPNVPAAVPAPSVP 519
            PQ V PPQ   + P+   P  PH       A  PG             +V A VP   VP
Sbjct: 988  PQPVLPPQP--ALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP 1045

Query: 520  SVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573
              +  S  +P V  P A        + ++  S+ +Q V  P    T   P + P
Sbjct: 1046 PAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSV--PTQTATLLPPANPP 1097



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 75/309 (24%), Positives = 106/309 (34%), Gaps = 46/309 (14%)

Query: 230  ASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSS 289
            AS  G  G   G  S L   +  P +E    P   QP    VG     P P   +   +S
Sbjct: 1414 ASQAGGPGTPQGLTSELE--TSQPLAETHEAPLAVQP--LVVGLAPCTPAPEAASTRDAS 1469

Query: 290  APLPPFPGAATGPQPMMAAAQPSQPQ-----GAGPGGQTLPPTNVTLAQPAMSLPPQPGP 344
            AP  P P  A  P P     QP+  Q      A  G  +L  + +       ++PPQP  
Sbjct: 1470 APREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPS 1529

Query: 345  AVGAPAAQQPQQFAYP----------------QPQIPPGHLLPVQP--SGQSEYLQQHVA 386
            A+ +     P +  +                 Q  +P        P   G  ++  + + 
Sbjct: 1530 ALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLR 1589

Query: 387  GLQPPSPAQPSSTGAAASPATAAT----LP---VGTGQNASSVGAQL-MGASSQPSEAMA 438
            G QP S            P  A +    LP   V   + A + GA +  G SS  +   +
Sbjct: 1590 GDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESS 1649

Query: 439  PRT---------GPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAG-AGQPQSVPPP-QMG 487
            PR+           A    V P  P  VP       V+P     G AG+  + PPP  MG
Sbjct: 1650 PRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMG 1709

Query: 488  GSGPLSAVP 496
              G  ++ P
Sbjct: 1710 TVGGQASHP 1718



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 57/230 (24%), Positives = 77/230 (33%), Gaps = 35/230 (15%)

Query: 238  PESGTDSSLTAVSQLPP-------------SEKMSQPTPAQPQSFSVGQPQPPPPPVGGA 284
            PE+   S    +S LPP             S K      A  Q  S   P  PP      
Sbjct: 1324 PEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAP 1383

Query: 285  VAQSSAPLPPFP--GAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQP 342
            +A SS P+   P  GAA     M   A  +  Q  GPG      + +  +QP       P
Sbjct: 1384 LAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAP 1443

Query: 343  ----------GPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPS 392
                       P   AP A   +  + P+  +PP    P   SG  +        L  P+
Sbjct: 1444 LAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQ------PALGQPA 1497

Query: 393  PAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTG 442
            P  P++ GA     + AT  + +     +V  Q   A     E   PR G
Sbjct: 1498 PLLPAAVGA----VSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVG 1543



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 77/289 (26%), Positives = 112/289 (38%), Gaps = 55/289 (19%)

Query: 391  PSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPS----EAMAPRTGPAQ- 445
            P+P  P S+     P   ++LP    Q+++    QL  +  QPS    + +  + GP+  
Sbjct: 1322 PAPEAPESS----PPLPLSSLPPEASQDSAPYKDQL-SSKEQPSFLASQQLLSQAGPSNP 1376

Query: 446  -GGQVAPCQPTGVP----------PATVGGVVQPCLGPA----GAGQPQSVPPPQMGGSG 490
             G   AP  P+  P          PAT   + +P  G A    G G PQ +   ++  S 
Sbjct: 1377 PGAPPAPLAPSSPPVTALPQDGAAPAT-STMPEPASGTASQAGGPGTPQGLTS-ELETSQ 1434

Query: 491  PLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRS 550
            PL+     P AV P V  +    PAP   + ST   + P  P P   + + S H+   + 
Sbjct: 1435 PLAETHEAPLAVQPLVVGLAPCTPAPE--AASTRDASAPREPLP-PPAPEPSPHSGTPQP 1491

Query: 551  SSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIA 610
            +       LP A G  S  TS         Q  + PL   V          PQPP +L +
Sbjct: 1492 ALGQPAPLLPAAVGAVSLATS---------QLPSPPLGPTVP---------PQPPSALES 1533

Query: 611  ENK-PVVKPPVADSLANPLQ-----LTPMNSLATSVFSIAIPVD-GDED 652
            + + P  +    DS    L      L     + TS  S   PV+ GD D
Sbjct: 1534 DGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRD 1582


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 148/638 (23%), Positives = 211/638 (33%), Gaps = 107/638 (16%)

Query: 36   PDESRTEDVSSEIFDVSRATDYGPEEVCERSSSEETLNNVGDAETPGTVSPNLLLDGQLA 95
            P  S    ++S+ F  S   +  P +     +   T + V      G    +L+   + +
Sbjct: 678  PVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGV---SLVYSDKKS 734

Query: 96   AAAAAPANGGGVVSARSVSGALASTLAAAATS------------APAP--------GAPG 135
            AAA +PA          V+G L  T+  A  +            APAP        GAPG
Sbjct: 735  AAATSPA-------PHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPG 787

Query: 136  GPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVL 195
            G   AGS AG  +      P                G   + G  T ++Y        + 
Sbjct: 788  GGTTAGSGAGAGSGPNGPVPLGILQ----------PGALGKAGGITQVQYILPTLPQQLQ 837

Query: 196  TRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPS 255
                                 G  A   S      S++    P + T+  + A +   P 
Sbjct: 838  VAPAPAPA------------PGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPG 885

Query: 256  EKMSQPTPAQP--QSFSVGQPQPPPPP------VGGAVAQSSAPLPPFPGAATGPQPMMA 307
              + Q  P+ P  ++ SV   Q PPP        G  +   +AP     G   G QP+  
Sbjct: 886  IPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAG-QPLPL 944

Query: 308  AAQP-SQP--QGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP-- 362
             + P S P   GA P  + +  T V ++ P+  +PP     +  P +Q PQ+   P    
Sbjct: 945  VSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQ-PQKVLLPSSTR 1003

Query: 363  ----QIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQN 418
                Q   GH LP+  S  S      V    P S      T    S   A   P+ +   
Sbjct: 1004 ITYVQSAGGHALPLGTSPASSQAGT-VTSYGPTSSVALGFTSLGPS-GPAFVQPLLSAGQ 1061

Query: 419  ASSVGAQLMGASSQPSEAMAPRTGPAQG--------GQVAP------CQPTGVPPATVGG 464
            A  +    +G S  PS  + P      G        G  AP       QP+  PP+ V  
Sbjct: 1062 APLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYT 1121

Query: 465  VVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAV-PAPSVPSVST 523
            V      PA    P+  P P      P S  P      +      P A  P+P  P    
Sbjct: 1122 VATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAP--QK 1179

Query: 524  TSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQT- 582
                + ++P    ++       P  R          PL PG    PT+ P+S+L    T 
Sbjct: 1180 VKAAIASIPVGSFEAGASGRPGPAPRQ---------PLEPGPVREPTA-PESELEGQPTP 1229

Query: 583  -QTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPP 619
                PL      T R S PLP P     AE +   K P
Sbjct: 1230 PAPPPLPETWTPTARSSPPLPPP-----AEERTSAKGP 1262



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 135/554 (24%), Positives = 193/554 (34%), Gaps = 108/554 (19%)

Query: 77   DAETPGTVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAPGAPGG 136
            D E PG   P +          +AP++     ++ S S A + +L +    A   G    
Sbjct: 511  DPEPPGPPDPPVAFG---KGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQ--- 564

Query: 137  PQLAGSSAGPVTAAP--SQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSV 194
                GS+AGP+   P  +  P T S   R + +D  +   +RR R   +   E    S +
Sbjct: 565  ----GSTAGPLRPPPPGAGGPATPSKATRFLPMDPAT---FRRKRPESVGGLEPPGPSVI 617

Query: 195  LT--RSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQL 252
                  G  I  +       E   G GA   S      +      P S   +++      
Sbjct: 618  AAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVR 677

Query: 253  PPSEKMSQPTPAQPQSFSV-GQPQPPPPPVGGAVAQ--------SSAPL-------PPFP 296
            P S   S P P   + F   G+ +  P    GA  +          +PL           
Sbjct: 678  PVS---STPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKS 734

Query: 297  GAATGPQPMMAAAQPSQPQGAGPGGQTL----PPTNVTLAQPAMSLPPQPGPAVGAPAAQ 352
             AAT P P + A       G  P   T      P     A PA+    Q  P  G  A  
Sbjct: 735  AAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGS 794

Query: 353  QPQQFAYPQPQIPPGHLLP--VQPSG---QSEYL------QQHVAGLQPPSPAQPSSTGA 401
                 + P   +P G L P  +  +G   Q +Y+      Q  VA    P+P   ++  +
Sbjct: 795  GAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPS 854

Query: 402  AASPATAA--TLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPP 459
              +P T+   TLP GT  N   + A                T P  G  +    P+  PP
Sbjct: 855  GPAPTTSIRFTLPPGTSTNGKVLAA----------------TAPTPGIPILQSVPSAPPP 898

Query: 460  ATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSV- 518
                             + QSV P Q       +  PGG   ++PG   VP A P+ SV 
Sbjct: 899  -----------------KAQSVSPVQ-------APPPGGSAQLLPGKVLVPLAAPSMSVR 934

Query: 519  --------PSVSTT-SVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAP 569
                    P VS   SV + N   P ++  QL+   PVS  S ++     PL+P T   P
Sbjct: 935  GGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTP-VPVSTPSGLVP----PLSPATLPGP 989

Query: 570  TSLPQSDLSQFQTQ 583
            TS PQ  L    T+
Sbjct: 990  TSQPQKVLLPSSTR 1003



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 154/675 (22%), Positives = 214/675 (31%), Gaps = 137/675 (20%)

Query: 32  SLDDPDESRTEDVSSEIFDVSRATDYGPEEVCERSSS--EETLNNVGDAETPGTVSPNLL 89
           S+ +   +    VSSE+  V+  T    +     SSS   E L+ VG    PG+  P   
Sbjct: 299 SMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGG---PGSARPRAF 355

Query: 90  LDGQLAAAAAAPANGGGVVSARSVSGALASTLAAAATSAPAP----GAPGGPQLAGSSAG 145
                 + +   +  GG V ++++          A+ S P P    GAPG P  A    G
Sbjct: 356 ------SHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPG-PFAAPGEGG 408

Query: 146 PVTAAPSQP--PTTCSSRFRVIKLDHGSGEPYRRGRWTCMEYYERDSDSSVLTRSGDCIR 203
            + A    P  PT  S   R    D  S E         M   E + D  V+   G    
Sbjct: 409 ALAATGRPPLLPTRASRSQRAASEDMTSDEER-------MVICEEEGDDDVIADDGFGTT 461

Query: 204 HSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTP 263
                 +    DS  G + G              PE          S +  S       P
Sbjct: 462 DIDLKCKERVTDSESGDSSGE------------DPEGNKGFGRKVFSPVIRSSFTHCRPP 509

Query: 264 AQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQT 323
             P+      P PP PPV       SAP      +A+ P    A+A  S   G+G    T
Sbjct: 510 LDPEP-----PGPPDPPVAFGKGYGSAP----SSSASSPASSSASAATSFSLGSG----T 556

Query: 324 LPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQ 383
                      A  L P P P  G PA                   LP+ P+       +
Sbjct: 557 FKAQESGQGSTAGPLRPPP-PGAGGPATPSKAT-----------RFLPMDPATFRRKRPE 604

Query: 384 HVAGLQPPSP----AQPS---------------------------------STGAAASPA 406
            V GL+PP P    A PS                                 + GA A+P 
Sbjct: 605 SVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPL 664

Query: 407 T--AATLPVGTGQNASSVGAQLMG--------ASSQPSEAMAPRTGPAQGGQVAPCQPTG 456
           +  AAT+     +  SS    +          A + P++    RT    G +V    P G
Sbjct: 665 SRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLG 724

Query: 457 VPPATVGGVVQPCLGPAGAGQPQSVPPPQMG--GSGP------LSAVPGGPHAVVPGVPN 508
           V              PA    P  V  P +G  G  P      L   PG      P V  
Sbjct: 725 VSLVYSDKKSAAATSPA----PHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQF 780

Query: 509 VPAAVPAPSVPSVSTTSV-TMPNVPAPLA--QSQQLSSHTPVSRSSSIIQHVGLPL---- 561
           +    P     + S     + PN P PL   Q   L     +++   I+  +   L    
Sbjct: 781 IAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAP 840

Query: 562 ----APGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVK 617
               APGT +A  S P +  +  +    P           + P P  P   I ++ P   
Sbjct: 841 APAPAPGTKAAAPSGP-APTTSIRFTLPPGTSTNGKVLAATAPTPGIP---ILQSVPSAP 896

Query: 618 PPVADSLANPLQLTP 632
           PP A S+ +P+Q  P
Sbjct: 897 PPKAQSV-SPVQAPP 910



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 54/211 (25%), Positives = 71/211 (33%), Gaps = 39/211 (18%)

Query: 240  SGTDSSLTAVSQLPPSEKMSQPTPAQP--------QSFSVGQP--QPPPP---------- 279
            S T  + T + + PP+   + P P  P         ++S+  P  Q P P          
Sbjct: 1125 STTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAI 1184

Query: 280  ---PVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAM 336
               PVG   A +S    P P     P P+     P       P     PP   T    A 
Sbjct: 1185 ASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTAR 1244

Query: 337  SLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPA-- 394
            S PP P PA    +A+ P+  A   P       +P Q       L+       PPSPA  
Sbjct: 1245 SSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQG------LENRGEPPTPPSPAPA 1298

Query: 395  --------QPSSTGAAASPATAATLPVGTGQ 417
                      SS+G AA          GTG+
Sbjct: 1299 PAVAPGGSSESSSGRAAGDTPERKEAAGTGK 1329



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 74/299 (24%), Positives = 101/299 (33%), Gaps = 43/299 (14%)

Query: 235  AHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQ----PQPPPPPVGGAVAQSSA 290
            ++GP S      T++    P+      +  Q    + GQ    P P P       A    
Sbjct: 1031 SYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGP 1090

Query: 291  PLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQ--PGPAVGA 348
             +  F   +  P      AQPSQ   A P       T+ T   PA ++ P+  P PA   
Sbjct: 1091 VITAFYSGSPAPTSSAPLAQPSQ---APPSLVYTVATSTT--PPAATILPKGPPAPATAT 1145

Query: 349  PAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATA 408
            PA   P                P   +G   Y       L  P   +PS        A  
Sbjct: 1146 PAPTSP---------------FPSATAGSMTY------SLVAPKAQRPSPKAPQKVKAAI 1184

Query: 409  ATLPVGTGQNASSVGAQLMGASSQPSEAMAPR--TGPAQ--GGQVAPCQPTGVPPA-TVG 463
            A++PVG+ +  +S   +   A  QP E    R  T P     GQ  P  P  +P   T  
Sbjct: 1185 ASIPVGSFEAGAS--GRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPT 1242

Query: 464  GVVQPCLGPAGAGQPQSVPPPQMGGSGPLSA----VPGGPHAVVPGVPNVPAAVPAPSV 518
                P L P    +  +  P  M    P S+    VPG         P  P+  PAP+V
Sbjct: 1243 ARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAV 1301



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 34/111 (30%), Positives = 38/111 (34%), Gaps = 28/111 (25%)

Query: 256  EKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQ 315
            +K+ Q      Q      P P PPP G A A +     P P  A GP P      PS   
Sbjct: 1516 QKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPA-----PTPSPAGGPDP----TSPSSDS 1566

Query: 316  GAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPP 366
            G       LPP            PP+ GP        QP     PQP  PP
Sbjct: 1567 GTAQAAPPLPP------------PPESGPG-------QPGWEGAPQPSPPP 1598



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 29/87 (33%), Positives = 35/87 (40%), Gaps = 16/87 (18%)

Query: 247  TAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGG----------AVAQSSAPLPPFP 296
            T   Q P +E    P P  P + +   P P P P GG            AQ++ PLPP P
Sbjct: 1523 TPTEQPPGAEA---PLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPP 1579

Query: 297  GAATGPQPMMAAAQPSQPQGAGPGGQT 323
             +  G      A QPS P    PG  T
Sbjct: 1580 ESGPGQPGWEGAPQPSPPP---PGPST 1603



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 3/73 (4%)

Query: 387  GLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQG 446
            G + P P  P  TG AA+PA   + P G G + +S  +    A + P     P +GP Q 
Sbjct: 1530 GAEAPLPVPPP-TGTAAAPAPTPS-PAG-GPDPTSPSSDSGTAQAAPPLPPPPESGPGQP 1586

Query: 447  GQVAPCQPTGVPP 459
            G     QP+  PP
Sbjct: 1587 GWEGAPQPSPPPP 1599



 Score = 33.9 bits (76), Expect = 0.60
 Identities = 33/111 (29%), Positives = 41/111 (36%), Gaps = 12/111 (10%)

Query: 52   SRATDYGPEEVCERSSSEETLNNVGDAETPGTVSPNLLLD-------GQLAAAAAAPANG 104
            +R  D  P +VC +    E    +  A TP    P            G  AA A  P+  
Sbjct: 1495 ARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPA 1554

Query: 105  GGV----VSARSVSGALASTLAAAATSAPA-PGAPGGPQLAGSSAGPVTAA 150
            GG      S+ S +   A  L     S P  PG  G PQ +    GP TAA
Sbjct: 1555 GGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAA 1605



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 26/76 (34%), Positives = 29/76 (38%), Gaps = 8/76 (10%)

Query: 454  PTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSG----PLSAVP-GGPHAVVPGVPN 508
            P  VPP T G    P   P+ AG P    P    G+     PL   P  GP    PG   
Sbjct: 1534 PLPVPPPT-GTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQ--PGWEG 1590

Query: 509  VPAAVPAPSVPSVSTT 524
             P   P P  PS + T
Sbjct: 1591 APQPSPPPPGPSTAAT 1606



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 3/65 (4%)

Query: 223  GSVVVVVASMQGAHGPESGTDSSLTAVSQL-PPSEKMSQPTPAQPQSFSVGQPQPPPPPV 281
            G+      +   A GP+  + SS +  +Q  PP     +  P QP     G PQP PPP 
Sbjct: 1542 GTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGW--EGAPQPSPPPP 1599

Query: 282  GGAVA 286
            G + A
Sbjct: 1600 GPSTA 1604



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 24/94 (25%), Positives = 29/94 (30%), Gaps = 3/94 (3%)

Query: 274 PQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQ 333
           P  P P V  + AQ  A  P     +  P    A A    P G G      PP       
Sbjct: 46  PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPES 105

Query: 334 PAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPG 367
           P    P  P P     + + P      +   PPG
Sbjct: 106 PG---PGPPHPLGVVESGKGPPPTTEEEASGPPG 136


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.125    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,916,386
Number of Sequences: 37866
Number of extensions: 2766588
Number of successful extensions: 40166
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 462
Number of HSP's successfully gapped in prelim test: 2325
Number of HSP's that attempted gapping in prelim test: 16485
Number of HSP's gapped (non-prelim): 15153
length of query: 780
length of database: 18,247,518
effective HSP length: 110
effective length of query: 670
effective length of database: 14,082,258
effective search space: 9435112860
effective search space used: 9435112860
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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