Guide to the Human Genome
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Search of human proteins with 7662034

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662034 Sac domain-containing inositol phosphatase 3 [Homo
sapiens]
         (907 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662034 Sac domain-containing inositol phosphatase 3 [Homo sa...  1835   0.0  
gi|190014578 suppressor of actin 1 [Homo sapiens]                     175   2e-43
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                  132   1e-30
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                  130   7e-30
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                  130   7e-30
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                  130   7e-30
gi|7662414 inositol polyphosphate-5-phosphatase F [Homo sapiens]      128   3e-29
gi|26190608 synaptojanin 2 [Homo sapiens]                             105   2e-22
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]      42   0.003
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]      42   0.003
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]      42   0.003
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]       42   0.003
gi|242332527 hypothetical protein LOC65250 [Homo sapiens]              37   0.064
gi|217416343 fibrosin-like 1 [Homo sapiens]                            36   0.19 
gi|31543811 proline rich Gla (G-carboxyglutamic acid) 3 (transme...    35   0.32 
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    34   0.71 
gi|11276067 snail 2 [Homo sapiens]                                     33   0.92 
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform...    33   0.92 
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    33   1.2  
gi|239746609 PREDICTED: hypothetical protein XP_002343799 [Homo ...    33   1.2  
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    33   1.6  
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    33   1.6  
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    33   1.6  
gi|7662022 lipin 2 [Homo sapiens]                                      33   1.6  
gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens]    33   1.6  
gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens]    33   1.6  
gi|46852392 chromobox homolog 6 [Homo sapiens]                         33   1.6  
gi|32967599 ankyrin 3 isoform 2 [Homo sapiens]                         32   2.1  
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         32   2.1  
gi|32479521 dishevelled 1 [Homo sapiens]                               32   2.7  

>gi|7662034 Sac domain-containing inositol phosphatase 3 [Homo
           sapiens]
          Length = 907

 Score = 1835 bits (4752), Expect = 0.0
 Identities = 907/907 (100%), Positives = 907/907 (100%)

Query: 1   MPTAAAPIISSVQKLVLYETRARYFLVGSNNAETKYRVLKIDRTEPKDLVIIDDRHVYTQ 60
           MPTAAAPIISSVQKLVLYETRARYFLVGSNNAETKYRVLKIDRTEPKDLVIIDDRHVYTQ
Sbjct: 1   MPTAAAPIISSVQKLVLYETRARYFLVGSNNAETKYRVLKIDRTEPKDLVIIDDRHVYTQ 60

Query: 61  QEVRELLGRLDLGNRTKMGQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIG 120
           QEVRELLGRLDLGNRTKMGQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIG
Sbjct: 61  QEVRELLGRLDLGNRTKMGQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIG 120

Query: 121 GHAIYKVEDTNMIYIPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLT 180
           GHAIYKVEDTNMIYIPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLT
Sbjct: 121 GHAIYKVEDTNMIYIPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLT 180

Query: 181 VLRMPLEMLKSEMTQNRQESFDIFEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIKS 240
           VLRMPLEMLKSEMTQNRQESFDIFEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIKS
Sbjct: 181 VLRMPLEMLKSEMTQNRQESFDIFEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIKS 240

Query: 241 TVHRDWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVE 300
           TVHRDWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVE
Sbjct: 241 TVHRDWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVE 300

Query: 301 TEQILCDASVMSFTAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHVAALH 360
           TEQILCDASVMSFTAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHVAALH
Sbjct: 301 TEQILCDASVMSFTAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHVAALH 360

Query: 361 FDQMFQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAK 420
           FDQMFQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAK
Sbjct: 361 FDQMFQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAK 420

Query: 421 YTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTG 480
           YTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTG
Sbjct: 421 YTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTG 480

Query: 481 ILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDT 540
           ILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDT
Sbjct: 481 ILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDT 540

Query: 541 LSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHP 600
           LSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHP
Sbjct: 541 LSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHP 600

Query: 601 TEGKPHLWELPTDFYLHHKNTMRLLPTRRSYTYWWTPEVIKHLPLPYDEVICAVNLKKLI 660
           TEGKPHLWELPTDFYLHHKNTMRLLPTRRSYTYWWTPEVIKHLPLPYDEVICAVNLKKLI
Sbjct: 601 TEGKPHLWELPTDFYLHHKNTMRLLPTRRSYTYWWTPEVIKHLPLPYDEVICAVNLKKLI 660

Query: 661 VKKFHKYEEEIDIHNEFFRPYELSSFDDTFCLAMTSSARDFMPKTVGIDPSPFTVRKPDE 720
           VKKFHKYEEEIDIHNEFFRPYELSSFDDTFCLAMTSSARDFMPKTVGIDPSPFTVRKPDE
Sbjct: 661 VKKFHKYEEEIDIHNEFFRPYELSSFDDTFCLAMTSSARDFMPKTVGIDPSPFTVRKPDE 720

Query: 721 TGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREEEGSVSQRSTPVK 780
           TGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREEEGSVSQRSTPVK
Sbjct: 721 TGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREEEGSVSQRSTPVK 780

Query: 781 MTDAGDSAKVTENVVQPMKELYGINLSDGLSEEDFSIYSRFVQLGQSQHKQDKNSQQPCS 840
           MTDAGDSAKVTENVVQPMKELYGINLSDGLSEEDFSIYSRFVQLGQSQHKQDKNSQQPCS
Sbjct: 781 MTDAGDSAKVTENVVQPMKELYGINLSDGLSEEDFSIYSRFVQLGQSQHKQDKNSQQPCS 840

Query: 841 RCSDGVIKLTPISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDSSMYRE 900
           RCSDGVIKLTPISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDSSMYRE
Sbjct: 841 RCSDGVIKLTPISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDSSMYRE 900

Query: 901 YIRNRYL 907
           YIRNRYL
Sbjct: 901 YIRNRYL 907


>gi|190014578 suppressor of actin 1 [Homo sapiens]
          Length = 587

 Score =  175 bits (444), Expect = 2e-43
 Identities = 149/523 (28%), Positives = 245/523 (46%), Gaps = 79/523 (15%)

Query: 93  FGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKVEDTNMIYIPNDSVRVTH---PDEAR 149
           FG++G +  + G Y+++ITK+ K+ +   H ++K  D +++      + +T     D   
Sbjct: 58  FGILGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKT 117

Query: 150 YLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMTQNRQESFDIFEDEGL 209
           +L +  +V     FYFS +YDL+H+LQ                ++    E    F++  L
Sbjct: 118 FLAMLNHVLNVDGFYFSTTYDLTHTLQ---------------RLSNTSPE----FQEMSL 158

Query: 210 ITQGGSGVFGICSEPYMKYVWNGELLDIIKST--VHRDWLLYIIHGFCGQSKLLIYGRPV 267
           + +              ++VWNG LL  + +   VHR + L ++HGF       I G+  
Sbjct: 159 LERADQ-----------RFVWNGHLLRELSAQPEVHR-FALPVLHGFITMHSCSINGKYF 206

Query: 268 YVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSYVQVRGS 327
              LI+RRS   AG R+  RG + EG  AN VETEQI+          GS +S+VQ RGS
Sbjct: 207 DWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIV-------HYNGSKASFVQTRGS 259

Query: 328 VPLYWSQDIS-TMMPKPPIT--LDQADPFAHVAALHFDQMFQRFGSPIIILNLVKEREKR 384
           +P++WSQ  +    P P I+   +  D F      HFD     +G  +II NL+ ++   
Sbjct: 260 IPVFWSQRPNLKYKPLPQISKVANHMDGFQR----HFDSQVIIYGKQVII-NLINQKGS- 313

Query: 385 KHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKT 444
             E+ L +     V+ L   +     + YI +D  K  K+      DRL+++ + V +  
Sbjct: 314 --EKPLEQTFATMVSSLGSGM-----MRYIAFDFHKECKNMR---WDRLSILLDQVAE-- 361

Query: 445 GFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCA 504
              +    SY  +        +  G V+     Q G+ R+NC+DCLDRTN  Q ++ + +
Sbjct: 362 ---MQDELSYFLV--------DSAGQVVAN---QEGVFRSNCMDCLDRTNVIQSLLARRS 407

Query: 505 LAYQLYSLGLID-KPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPW 563
           L  QL  LG++     L+   +  ++++  + D+ +  + QY G+  +    T       
Sbjct: 408 LQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTH 467

Query: 564 TQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGKPH 606
                D   ++ RYY N FSD  RQDSI+LFLG +   E + H
Sbjct: 468 LGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDELESH 510


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score =  132 bits (332), Expect = 1e-30
 Identities = 141/520 (27%), Positives = 230/520 (44%), Gaps = 103/520 (19%)

Query: 88  RAVSAFGVVGFVRFLEG----YYIVLITKRRKMADIGGHAIYKVEDTNMIYIPNDSVRVT 143
           + + A+G++G +R   G    +Y+VL+T    +  I    +++V  T  I     S+R+ 
Sbjct: 55  KVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFI-----SLRID 109

Query: 144 HPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMTQNRQESFDI 203
             DE R   + + V  S NFYF++S     SL  +L   R     ++ + T NR      
Sbjct: 110 SSDEDRISEV-RKVLNSGNFYFAWSAS-GISLDLSLNAHRS----MQEQTTDNR------ 157

Query: 204 FEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIK--STVHRDWLLYIIHGFCGQSKLL 261
                                   + WN  L   +K       DWLL ++ G      + 
Sbjct: 158 ------------------------FFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIY 193

Query: 262 IYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSY 321
              +     LI+R S + AGTRF  RG N +G VAN VETEQ++       +   S SS+
Sbjct: 194 AAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVV-------YLDDSVSSF 246

Query: 322 VQVRGSVPLYWSQDISTMMPKPPITLDQA-DPFAHVAALHFDQMFQRFGSPIIILNLVKE 380
           +Q+RGSVPL+W Q     +    + + +  +  A     HF  +   +G  II+ NL+  
Sbjct: 247 IQIRGSVPLFWEQP-GLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIV-NLLGS 304

Query: 381 REKRKHERILSEELVAAVTYLNQFLPPEHT--IVYIPWDMAKYTKSKLCNVLDRLNVIAE 438
           +E    E +LS+       + +     EH   I  + +D  +  K       ++L+ + +
Sbjct: 305 KEG---EHMLSK------AFQSHLKASEHAADIQMVNFDYHQMVKG---GKAEKLHSVLK 352

Query: 439 SVVKKT---GFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNT 495
             V+K    GFF                     G  +   R Q+G +RTNC+DCLDRTN+
Sbjct: 353 PQVQKFLDYGFFY------------------FNGSEVQ--RCQSGTVRTNCLDCLDRTNS 392

Query: 496 AQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVK 555
            Q  +G   LA QL +LGL +KP  Q  T    +F  ++  +GD++S  Y G+  +    
Sbjct: 393 VQAFLGLEMLAKQLEALGLAEKP--QLVTRFQEVFRSMWSVNGDSISKIYAGTGALEGKA 450

Query: 556 TYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFL 595
              K+       KD  ++++R   N F D+ +Q++I++ L
Sbjct: 451 KAGKL-------KDGARSVTRTIQNNFFDSSKQEAIDVLL 483


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score =  130 bits (326), Expect = 7e-30
 Identities = 142/521 (27%), Positives = 230/521 (44%), Gaps = 108/521 (20%)

Query: 88  RAVSAFGVVGFVRFLEG----YYIVLITKRRKMADIGGHAIYKVEDTNMIYIPNDSVRVT 143
           + + A+G++G +R   G    +Y+VL+T    +  I    +++V  T  I     S+R+ 
Sbjct: 55  KVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFI-----SLRID 109

Query: 144 HPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMTQNRQESFDI 203
             DE R   + + V  S NFYF++S     SL  +L   R     ++ + T NR      
Sbjct: 110 SSDEDRISEV-RKVLNSGNFYFAWSAS-GISLDLSLNAHRS----MQEQTTDNR------ 157

Query: 204 FEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIK--STVHRDWLLYIIHGFCGQSKLL 261
                                   + WN  L   +K       DWLL ++ G      + 
Sbjct: 158 ------------------------FFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIY 193

Query: 262 IYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSY 321
              +     LI+R S + AGTRF  RG N +G VAN VETEQ++       +   S SS+
Sbjct: 194 AAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVV-------YLDDSVSSF 246

Query: 322 VQVRGSVPLYWSQDISTMMPKPPITLDQA-DPFAHVAALHFDQMFQRFGSPIIILNLVKE 380
           +Q+RGSVPL+W Q     +    + + +  +  A     HF  +   +G  II+ NL+  
Sbjct: 247 IQIRGSVPLFWEQP-GLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIV-NLLGS 304

Query: 381 REKRKHERILSEELVAAVTYLNQFLPPEHT--IVYIPWDMAKYTKSKLCNVLDRLNVIAE 438
           +E    E +LS+       + +     EH   I  + +D  +  K       ++L+ + +
Sbjct: 305 KEG---EHMLSK------AFQSHLKASEHAADIQMVNFDYHQMVKG---GKAEKLHSVLK 352

Query: 439 SVVKKT---GFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNT 495
             V+K    GFF                     G  +   R Q+G +RTNC+DCLDRTN+
Sbjct: 353 PQVQKFLDYGFFY------------------FNGSEVQ--RCQSGTVRTNCLDCLDRTNS 392

Query: 496 AQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGS-QLVHRV 554
            Q  +G   LA QL +LGL +KP  Q  T    +F  ++  +GD++S  Y G+  L  + 
Sbjct: 393 VQAFLGLEMLAKQLEALGLAEKP--QLVTRFQEVFRSMWSVNGDSISKIYAGTGALEGKA 450

Query: 555 KTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFL 595
           K            KD  ++++R   N F D+ +Q++I++ L
Sbjct: 451 KL-----------KDGARSVTRTIQNNFFDSSKQEAIDVLL 480


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score =  130 bits (326), Expect = 7e-30
 Identities = 142/521 (27%), Positives = 230/521 (44%), Gaps = 108/521 (20%)

Query: 88  RAVSAFGVVGFVRFLEG----YYIVLITKRRKMADIGGHAIYKVEDTNMIYIPNDSVRVT 143
           + + A+G++G +R   G    +Y+VL+T    +  I    +++V  T  I     S+R+ 
Sbjct: 94  KVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFI-----SLRID 148

Query: 144 HPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMTQNRQESFDI 203
             DE R   + + V  S NFYF++S     SL  +L   R     ++ + T NR      
Sbjct: 149 SSDEDRISEV-RKVLNSGNFYFAWSAS-GISLDLSLNAHRS----MQEQTTDNR------ 196

Query: 204 FEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIK--STVHRDWLLYIIHGFCGQSKLL 261
                                   + WN  L   +K       DWLL ++ G      + 
Sbjct: 197 ------------------------FFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIY 232

Query: 262 IYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSY 321
              +     LI+R S + AGTRF  RG N +G VAN VETEQ++       +   S SS+
Sbjct: 233 AAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVV-------YLDDSVSSF 285

Query: 322 VQVRGSVPLYWSQDISTMMPKPPITLDQA-DPFAHVAALHFDQMFQRFGSPIIILNLVKE 380
           +Q+RGSVPL+W Q     +    + + +  +  A     HF  +   +G  II+ NL+  
Sbjct: 286 IQIRGSVPLFWEQP-GLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIV-NLLGS 343

Query: 381 REKRKHERILSEELVAAVTYLNQFLPPEHT--IVYIPWDMAKYTKSKLCNVLDRLNVIAE 438
           +E    E +LS+       + +     EH   I  + +D  +  K       ++L+ + +
Sbjct: 344 KEG---EHMLSK------AFQSHLKASEHAADIQMVNFDYHQMVKG---GKAEKLHSVLK 391

Query: 439 SVVKKT---GFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNT 495
             V+K    GFF                     G  +   R Q+G +RTNC+DCLDRTN+
Sbjct: 392 PQVQKFLDYGFFY------------------FNGSEVQ--RCQSGTVRTNCLDCLDRTNS 431

Query: 496 AQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGS-QLVHRV 554
            Q  +G   LA QL +LGL +KP  Q  T    +F  ++  +GD++S  Y G+  L  + 
Sbjct: 432 VQAFLGLEMLAKQLEALGLAEKP--QLVTRFQEVFRSMWSVNGDSISKIYAGTGALEGKA 489

Query: 555 KTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFL 595
           K            KD  ++++R   N F D+ +Q++I++ L
Sbjct: 490 KL-----------KDGARSVTRTIQNNFFDSSKQEAIDVLL 519


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score =  130 bits (326), Expect = 7e-30
 Identities = 142/521 (27%), Positives = 230/521 (44%), Gaps = 108/521 (20%)

Query: 88  RAVSAFGVVGFVRFLEG----YYIVLITKRRKMADIGGHAIYKVEDTNMIYIPNDSVRVT 143
           + + A+G++G +R   G    +Y+VL+T    +  I    +++V  T  I     S+R+ 
Sbjct: 94  KVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFI-----SLRID 148

Query: 144 HPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMTQNRQESFDI 203
             DE R   + + V  S NFYF++S     SL  +L   R     ++ + T NR      
Sbjct: 149 SSDEDRISEV-RKVLNSGNFYFAWSAS-GISLDLSLNAHRS----MQEQTTDNR------ 196

Query: 204 FEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIK--STVHRDWLLYIIHGFCGQSKLL 261
                                   + WN  L   +K       DWLL ++ G      + 
Sbjct: 197 ------------------------FFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIY 232

Query: 262 IYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSY 321
              +     LI+R S + AGTRF  RG N +G VAN VETEQ++       +   S SS+
Sbjct: 233 AAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVV-------YLDDSVSSF 285

Query: 322 VQVRGSVPLYWSQDISTMMPKPPITLDQA-DPFAHVAALHFDQMFQRFGSPIIILNLVKE 380
           +Q+RGSVPL+W Q     +    + + +  +  A     HF  +   +G  II+ NL+  
Sbjct: 286 IQIRGSVPLFWEQP-GLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIV-NLLGS 343

Query: 381 REKRKHERILSEELVAAVTYLNQFLPPEHT--IVYIPWDMAKYTKSKLCNVLDRLNVIAE 438
           +E    E +LS+       + +     EH   I  + +D  +  K       ++L+ + +
Sbjct: 344 KEG---EHMLSK------AFQSHLKASEHAADIQMVNFDYHQMVKG---GKAEKLHSVLK 391

Query: 439 SVVKKT---GFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNT 495
             V+K    GFF                     G  +   R Q+G +RTNC+DCLDRTN+
Sbjct: 392 PQVQKFLDYGFFY------------------FNGSEVQ--RCQSGTVRTNCLDCLDRTNS 431

Query: 496 AQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGS-QLVHRV 554
            Q  +G   LA QL +LGL +KP  Q  T    +F  ++  +GD++S  Y G+  L  + 
Sbjct: 432 VQAFLGLEMLAKQLEALGLAEKP--QLVTRFQEVFRSMWSVNGDSISKIYAGTGALEGKA 489

Query: 555 KTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFL 595
           K            KD  ++++R   N F D+ +Q++I++ L
Sbjct: 490 KL-----------KDGARSVTRTIQNNFFDSSKQEAIDVLL 519


>gi|7662414 inositol polyphosphate-5-phosphatase F [Homo sapiens]
          Length = 1132

 Score =  128 bits (321), Expect = 3e-29
 Identities = 97/330 (29%), Positives = 157/330 (47%), Gaps = 40/330 (12%)

Query: 269 VTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSYVQVRGSV 328
           V LI+RRS   AG R+ +RG +  G+VAN VETEQ++    V + T     S+VQ RGSV
Sbjct: 278 VALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLI---HVHNHTL----SFVQTRGSV 330

Query: 329 PLYWSQDISTMMPKPPITLDQADPFAHVAALHFDQMFQRFGSPIIILNLVKEREKRKHER 388
           P++WSQ      P+P +   + +  A+  A HF++    +   +II NLV +  +   E+
Sbjct: 331 PVFWSQVGYRYNPRPRLDRSEKETVAYFCA-HFEEQLNIYKKQVII-NLVDQAGR---EK 385

Query: 389 ILSEELVAAVTYLNQFLPPEHTIVYIPWDMAKYTKS-KLCNVLDRLNVIAESVVKKTGFF 447
           I+ +  +  V   N        + Y+ +D  ++ +  K  NV    + I + ++     +
Sbjct: 386 IIGDAYLKQVLLFNN-----SHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCW 440

Query: 448 VNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAY 507
           V+     C                      Q GI R NC+DCLDRTN  Q  + +  +  
Sbjct: 441 VDEAGVICK---------------------QEGIFRVNCMDCLDRTNVVQAAIARVVMEQ 479

Query: 508 QLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHS 567
           QL  LG++  P         R+++ ++ ++GD++S QY G+  +    T           
Sbjct: 480 QLKKLGVM-PPEQPLPVKCNRIYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVM 538

Query: 568 KDIMQTLSRYYSNAFSDADRQDSINLFLGV 597
           KD + + +RYY N F DA RQ  I+L  G+
Sbjct: 539 KDGVNSANRYYLNRFKDAYRQAVIDLMQGI 568


>gi|26190608 synaptojanin 2 [Homo sapiens]
          Length = 1496

 Score =  105 bits (262), Expect = 2e-22
 Identities = 138/531 (25%), Positives = 218/531 (41%), Gaps = 112/531 (21%)

Query: 81  KGSSGLFRAVSAFGVVGFVRFLEG----YYIVLITKRRKMADIGGHAIYKVEDTNMIYIP 136
           KG  G  +   A+G +G +R   G     ++VL+T    +  I    IYK+  T+   + 
Sbjct: 51  KGQYG--KLTDAYGCLGELRLKSGGTSLSFLVLVTGCTSVGRIPDAEIYKITATDFYPLQ 108

Query: 137 NDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMTQN 196
            ++       E   L   + +  S  FYFS+  D S   +++LTV            TQ 
Sbjct: 109 EEA------KEEERLIALKKILSSGVFYFSWPNDGS---RFDLTV-----------RTQK 148

Query: 197 RQESFDIFEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIKSTVHR----DWLLYIIH 252
           + +                      SE    + WN +LL +     H+    DWLL II 
Sbjct: 149 QGDD--------------------SSEWGNSFFWN-QLLHV-PLRQHQVSCCDWLLKIIC 186

Query: 253 GFCGQSKLLIYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMS 312
           G      +    +     L++R S +  GTRF  RG N +G V+N VETEQ       M 
Sbjct: 187 GVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQ-------MI 239

Query: 313 FTAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQA-DPFAHVAALHFDQMFQRFGSP 371
           +     SS+VQ+RGSVPL+W Q     +    + L +  +  A     H   + +++G  
Sbjct: 240 YMDDGVSSFVQIRGSVPLFWEQP-GLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQ 298

Query: 372 IIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLD 431
           +++ NL+  R   +      ++L+ A  +             I +D  ++ K      L+
Sbjct: 299 VVV-NLLGSRGGEEVLNRAFKKLLWASCHAGD-------TPMINFDFHQFAKGGKLEKLE 350

Query: 432 RLNVIAESVVKKTGFFVNRPDSYCSILRPDEK--WNEL-----GGCVIPTGRLQTGILRT 484
                                   ++LRP  K  W +      G  V P  R Q G LR 
Sbjct: 351 ------------------------TLLRPQLKLHWEDFDVFTKGENVSP--RFQKGTLRM 384

Query: 485 NCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQ 544
           NC+DCLDRTNT Q  +    L  QL +LGL  KP +      V  F+ ++  +G +LS  
Sbjct: 385 NCLDCLDRTNTVQSFIALEVLHLQLKTLGLSSKPIVD---RFVESFKAMWSLNGHSLSKV 441

Query: 545 YGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFL 595
           + GS+ +       K+       KD  +++SR   + F D  +Q++I L L
Sbjct: 442 FTGSRALEGKAKVGKL-------KDGARSMSRTIQSNFFDGVKQEAIKLLL 485


>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
          Length = 1312

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 43/161 (26%), Positives = 65/161 (40%), Gaps = 33/161 (20%)

Query: 717 KPDETGKSVLGNKSNREE-----------AVLQRKTAASAPPPPSE--EAVSSSSEDDSG 763
           KPD +     GNK+  ++            +L+ +T   AP PP +  +  SSS E +S 
Sbjct: 754 KPDSSPVLSPGNKAKPDDHRSRPGRPADFVLLKERTLDEAPRPPKKAMDYSSSSEEVESS 813

Query: 764 TDREEEG----SVSQRSTPVKMTDAGDSAKVTENVVQPMKELYGINLSDG---------- 809
            D EEEG    +   R TP   +D GD+  V+  VV  ++E+ G     G          
Sbjct: 814 EDDEEEGEGGPAEGSRDTPGGRSD-GDTDSVSTMVVHDVEEITGTQPPYGGGTMVVQRTP 872

Query: 810 -----LSEEDFSIYSRFVQLGQSQHKQDKNSQQPCSRCSDG 845
                L   D + Y+    + Q  H   +NS+       DG
Sbjct: 873 EEERNLLHADSNGYTNLPDVVQPSHSPTENSKGQSPPSKDG 913


>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
          Length = 1303

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 45/162 (27%), Positives = 68/162 (41%), Gaps = 29/162 (17%)

Query: 711 SPFTVRKPDETGKSVLGNKSNREEAV------LQRKTAASAPPPPSE--EAVSSSSEDDS 762
           SP    KPD+  +S  G  ++ + A+      L+ +T   AP PP +  +  SSS E +S
Sbjct: 745 SPGNKAKPDDH-RSRPGRPASYKRAIGEDFVLLKERTLDEAPRPPKKAMDYSSSSEEVES 803

Query: 763 GTDREEEG----SVSQRSTPVKMTDAGDSAKVTENVVQPMKELYGINLSDG--------- 809
             D EEEG    +   R TP   +D GD+  V+  VV  ++E+ G     G         
Sbjct: 804 SEDDEEEGEGGPAEGSRDTPGGRSD-GDTDSVSTMVVHDVEEITGTQPPYGGGTMVVQRT 862

Query: 810 ------LSEEDFSIYSRFVQLGQSQHKQDKNSQQPCSRCSDG 845
                 L   D + Y+    + Q  H   +NS+       DG
Sbjct: 863 PEEERNLLHADSNGYTNLPDVVQPSHSPTENSKGQSPPSKDG 904


>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
          Length = 1332

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 43/161 (26%), Positives = 65/161 (40%), Gaps = 33/161 (20%)

Query: 717 KPDETGKSVLGNKSNREE-----------AVLQRKTAASAPPPPSE--EAVSSSSEDDSG 763
           KPD +     GNK+  ++            +L+ +T   AP PP +  +  SSS E +S 
Sbjct: 774 KPDSSPVLSPGNKAKPDDHRSRPGRPADFVLLKERTLDEAPRPPKKAMDYSSSSEEVESS 833

Query: 764 TDREEEG----SVSQRSTPVKMTDAGDSAKVTENVVQPMKELYGINLSDG---------- 809
            D EEEG    +   R TP   +D GD+  V+  VV  ++E+ G     G          
Sbjct: 834 EDDEEEGEGGPAEGSRDTPGGRSD-GDTDSVSTMVVHDVEEITGTQPPYGGGTMVVQRTP 892

Query: 810 -----LSEEDFSIYSRFVQLGQSQHKQDKNSQQPCSRCSDG 845
                L   D + Y+    + Q  H   +NS+       DG
Sbjct: 893 EEERNLLHADSNGYTNLPDVVQPSHSPTENSKGQSPPSKDG 933


>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
          Length = 1295

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 43/161 (26%), Positives = 65/161 (40%), Gaps = 33/161 (20%)

Query: 717 KPDETGKSVLGNKSNREE-----------AVLQRKTAASAPPPPSE--EAVSSSSEDDSG 763
           KPD +     GNK+  ++            +L+ +T   AP PP +  +  SSS E +S 
Sbjct: 737 KPDSSPVLSPGNKAKPDDHRSRPGRPADFVLLKERTLDEAPRPPKKAMDYSSSSEEVESS 796

Query: 764 TDREEEG----SVSQRSTPVKMTDAGDSAKVTENVVQPMKELYGINLSDG---------- 809
            D EEEG    +   R TP   +D GD+  V+  VV  ++E+ G     G          
Sbjct: 797 EDDEEEGEGGPAEGSRDTPGGRSD-GDTDSVSTMVVHDVEEITGTQPPYGGGTMVVQRTP 855

Query: 810 -----LSEEDFSIYSRFVQLGQSQHKQDKNSQQPCSRCSDG 845
                L   D + Y+    + Q  H   +NS+       DG
Sbjct: 856 EEERNLLHADSNGYTNLPDVVQPSHSPTENSKGQSPPSKDG 896


>gi|242332527 hypothetical protein LOC65250 [Homo sapiens]
          Length = 3197

 Score = 37.4 bits (85), Expect = 0.064
 Identities = 44/197 (22%), Positives = 83/197 (42%), Gaps = 23/197 (11%)

Query: 648  DEVICAV-NLKKLIVKKFHKYEEEIDIHNEFFRPYELSSFDDTFCLAMTSSARDFMPKTV 706
            DE + A+ N+ + I + F K  E +D+H +   P +   F        T ++     KT+
Sbjct: 2708 DEQLLAIQNIAENIEQDFPK-PEMLDLHCDKIGPVDHIEFSSGPEFKKTLAS-----KTI 2761

Query: 707  GIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPP-PPSEEAVSSSSEDDSGT- 764
             I      +   DE  +S     S  E ++ +  +       P ++ AVS SS  D  T 
Sbjct: 2762 SISEEVRFLTHMDEEDQSDKKETSEPEFSITENYSGQKTCVFPTADSAVSLSSSSDQNTT 2821

Query: 765  ----DREEEGSVSQRSTPVKMTDAGDSAKVTENVVQPMKELYGINLSDGLSEEDFSIYSR 820
                +  +E   S    P++MT   D A + ++++          + DG+S E+  +  +
Sbjct: 2822 SPGMNSSDELCESVSVHPLQMTGLTDIADIIDDLI----------IKDGVSSEELGLTEQ 2871

Query: 821  FVQLGQSQHKQDKNSQQ 837
             +   + QH   ++SQ+
Sbjct: 2872 AMGTSRIQHYSGRHSQR 2888


>gi|217416343 fibrosin-like 1 [Homo sapiens]
          Length = 1045

 Score = 35.8 bits (81), Expect = 0.19
 Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 5/123 (4%)

Query: 696 SSARDFMPKTVGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVS 755
           S  +D  P   G    P    K  +   S  G++ + +++VL+  ++       S  AVS
Sbjct: 141 SPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVS 200

Query: 756 S---SSEDDSGTDREEEGSVSQRSTPVKMTDAGDSAKVTENVVQPMKELYGINLSDGLSE 812
               S + +SG D  ++ SV         TD G + + +E    P+ ++ G+  S  LS 
Sbjct: 201 GRGYSCDSESGPD--DKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELSA 258

Query: 813 EDF 815
           E F
Sbjct: 259 ESF 261


>gi|31543811 proline rich Gla (G-carboxyglutamic acid) 3
           (transmembrane) [Homo sapiens]
          Length = 231

 Score = 35.0 bits (79), Expect = 0.32
 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 5/70 (7%)

Query: 711 SPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREEEG 770
           SP  V  P   G++ +  +S      L     +S PPPPS E V++  E  S     EE 
Sbjct: 154 SPQVVLGPSRGGRTTVRLESTLYLPELSLSRLSSTPPPPSYEEVTAPQESSS-----EEA 208

Query: 771 SVSQRSTPVK 780
           SVS    P K
Sbjct: 209 SVSYSDPPPK 218


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 33.9 bits (76), Expect = 0.71
 Identities = 34/152 (22%), Positives = 61/152 (40%), Gaps = 11/152 (7%)

Query: 703  PKTVGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPS--EEAVSSSSED 760
            P T  I P+P        T  ++ GNKS    ++    T A+   P +     V  +++ 
Sbjct: 1664 PPTANIKPTPVVSTPSKVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQV 1723

Query: 761  DSGTDREEEGSVSQRSTPVKMTDAGDSAKVTENVVQPMKELYGINLSDGLSEEDFSIYSR 820
            +S    + EG V     PV  + +G     + NV   + +         L+ +  +  + 
Sbjct: 1724 ESQEAMQSEGPVEH--VPVFGSTSGSVRSTSPNVQPSISQPI-------LTVQQQTQATA 1774

Query: 821  FVQLGQSQHKQDKNSQQPCSRCSDGVIKLTPI 852
            FVQ  Q  H Q + + Q  S     V++ +P+
Sbjct: 1775 FVQPTQQSHPQIEPANQELSSNIVEVVQSSPV 1806


>gi|11276067 snail 2 [Homo sapiens]
          Length = 268

 Score = 33.5 bits (75), Expect = 0.92
 Identities = 31/110 (28%), Positives = 44/110 (40%), Gaps = 11/110 (10%)

Query: 670 EIDIHNEFFRPYELSSFD-DTFCLAMTSSARDFMPKTVGIDPSPFTVRKPDETGKSVLGN 728
           E+D H     PY   S+           S+  + P TV    +PF  + P+  G S L  
Sbjct: 21  ELDTHTVIISPYLYESYSMPVIPQPEILSSGAYSPITVWTTAAPFHAQLPN--GLSPLSG 78

Query: 729 KSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREEEGSVSQRSTP 778
            S+    V        +PPPPS+ +    S  +S    EEE   S+ S P
Sbjct: 79  YSSSLGRV--------SPPPPSDTSSKDHSGSESPISDEEERLQSKLSDP 120


>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
           [Homo sapiens]
          Length = 845

 Score = 33.5 bits (75), Expect = 0.92
 Identities = 20/101 (19%), Positives = 47/101 (46%), Gaps = 2/101 (1%)

Query: 717 KPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREEEGSVSQRS 776
           KP     ++   + ++EE +++ K         +++A   S E+  G + EEEG  S+  
Sbjct: 188 KPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGGESKAD 247

Query: 777 TPVKMTDAGDSAKVTENVVQPMKELYGINLSDGLSEEDFSI 817
            P       +  K+ +  ++  +++  +  ++  +E DFS+
Sbjct: 248 DPYAHLSKKEKKKLKKQ-MEYERQVASLKAANA-AENDFSV 286


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 24/97 (24%), Positives = 48/97 (49%), Gaps = 14/97 (14%)

Query: 716 RKPDETGKSVLGNKSNR----EEAVLQRKTAASAPPPPSEEAVSSSSEDD-------SGT 764
           ++PD+T K   G K++R     E   Q  ++++ P  PS+     +S+ +         T
Sbjct: 368 KEPDKTNKKE-GEKTDRVGVASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQT 426

Query: 765 DREEEGSVSQRSTPVKMTDAGDSAKVTENVVQPMKEL 801
           ++ EE +  + S P K+   GD  ++  +V QP+ ++
Sbjct: 427 EKAEEETRMENSLPAKVPSRGD--EMVADVQQPLSQI 461


>gi|239746609 PREDICTED: hypothetical protein XP_002343799 [Homo
           sapiens]
          Length = 245

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 8/73 (10%)

Query: 703 PKTVGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAA--SAPPPPSEEAVSSSSED 760
           P+TV I PS F+ R P   G+   G+ S  E A  QR+  +    P P  ++A   + E+
Sbjct: 11  PRTVAIKPSAFSRRNP---GREKDGSAS-LEGARRQRRVGSRQRTPGPDGQDASPRAREE 66

Query: 761 DSGTDREEEGSVS 773
           D G  RE  G +S
Sbjct: 67  DGG--RERRGGLS 77


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 15/98 (15%)

Query: 716 RKPDETGKSVLGNKSNR-----EEAVLQRKTAASAPPPPSEEAVSSSSEDD-------SG 763
           ++PD+T K   G K++R      E   Q  ++++ P  PS+     +S+ +         
Sbjct: 340 KEPDKTNKKE-GEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQ 398

Query: 764 TDREEEGSVSQRSTPVKMTDAGDSAKVTENVVQPMKEL 801
           T++ EE +  + S P K+   GD  ++  +V QP+ ++
Sbjct: 399 TEKAEEETRMENSLPAKVPSRGD--EMVADVQQPLSQI 434


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 15/98 (15%)

Query: 716 RKPDETGKSVLGNKSNR-----EEAVLQRKTAASAPPPPSEEAVSSSSEDD-------SG 763
           ++PD+T K   G K++R      E   Q  ++++ P  PS+     +S+ +         
Sbjct: 346 KEPDKTNKKE-GEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQ 404

Query: 764 TDREEEGSVSQRSTPVKMTDAGDSAKVTENVVQPMKEL 801
           T++ EE +  + S P K+   GD  ++  +V QP+ ++
Sbjct: 405 TEKAEEETRMENSLPAKVPSRGD--EMVADVQQPLSQI 440


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 15/98 (15%)

Query: 716 RKPDETGKSVLGNKSNR-----EEAVLQRKTAASAPPPPSEEAVSSSSEDD-------SG 763
           ++PD+T K   G K++R      E   Q  ++++ P  PS+     +S+ +         
Sbjct: 346 KEPDKTNKKE-GEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQ 404

Query: 764 TDREEEGSVSQRSTPVKMTDAGDSAKVTENVVQPMKEL 801
           T++ EE +  + S P K+   GD  ++  +V QP+ ++
Sbjct: 405 TEKAEEETRMENSLPAKVPSRGD--EMVADVQQPLSQI 440


>gi|7662022 lipin 2 [Homo sapiens]
          Length = 896

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 28/126 (22%), Positives = 53/126 (42%), Gaps = 4/126 (3%)

Query: 696 SSARDFMPKTVGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVS 755
           S  +D MPK  G     +  RK +   K +  +K  + EA       +S+  P       
Sbjct: 545 SWVKDKMPKKSG---RWWFWRKRESMTKQLPESKEGKSEAPPASDLPSSSKEPAGARPAE 601

Query: 756 SSSEDDSGTDREEEGSVSQRSTPVKMTDAGDSAKVTENVVQPMKELYGINLSDGLSEEDF 815
           + S  D G+   EE S++    P +    G +    +++     ++  + L DG ++  F
Sbjct: 602 NDSSSDEGSQELEE-SITVDPIPTEPLSHGSTTSYKKSLRLSSDQIAKLKLHDGPNDVVF 660

Query: 816 SIYSRF 821
           SI +++
Sbjct: 661 SITTQY 666


>gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens]
          Length = 1013

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 694 MTSSARDFMPKTVGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEA 753
           +TS+     P T G  P+P T      +  S   + S+   A     +++S+PPP S  A
Sbjct: 60  LTSAPLPLPPATGGAAPNPATTTAASSSSSSSSSSSSSSSSASSSSSSSSSSPPPASPPA 119

Query: 754 VS 755
            S
Sbjct: 120 SS 121


>gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens]
          Length = 1013

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 694 MTSSARDFMPKTVGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEA 753
           +TS+     P T G  P+P T      +  S   + S+   A     +++S+PPP S  A
Sbjct: 60  LTSAPLPLPPATGGAAPNPATTTAASSSSSSSSSSSSSSSSASSSSSSSSSSPPPASPPA 119

Query: 754 VS 755
            S
Sbjct: 120 SS 121


>gi|46852392 chromobox homolog 6 [Homo sapiens]
          Length = 412

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 10/97 (10%)

Query: 680 PYELSSFDDTFCLAMTSSARD-------FMPKTVGIDPSPFTVRKPDETGKSVLGNKSNR 732
           PY+  S   + C + T  + D        +P+TV   PS  + R+P+    S+    +  
Sbjct: 267 PYDARSSGSSGCPSPTPQSSDPDDTPPKLLPETVS--PSAPSWREPEVLDLSLPPESAAT 324

Query: 733 EEAVLQRKTAASAP-PPPSEEAVSSSSEDDSGTDREE 768
            +      TAA+ P PP + E   +SSE ++G  R E
Sbjct: 325 SKRAPPEVTAAAGPAPPTAPEPAGASSEPEAGDWRPE 361


>gi|32967599 ankyrin 3 isoform 2 [Homo sapiens]
          Length = 1001

 Score = 32.3 bits (72), Expect = 2.1
 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 13/95 (13%)

Query: 706 VGIDPSPFTVRKPDETGKSVLGNKSNREEAVL----QRK-----TAASAPPPPSEEAVSS 756
           VG+   P     PDE  K +LGNK+     V     +RK     T     PPPS E VS+
Sbjct: 311 VGLQAQPV----PDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSN 366

Query: 757 SSEDDSGTDREEEGSVSQRSTPVKMTDAGDSAKVT 791
             + D+  +     S++  ++P +  D   +  +T
Sbjct: 367 GYKGDTTPNLRLLCSITGGTSPAQWEDITGTTPLT 401


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 32.3 bits (72), Expect = 2.1
 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 13/95 (13%)

Query: 706  VGIDPSPFTVRKPDETGKSVLGNKSNREEAVL----QRK-----TAASAPPPPSEEAVSS 756
            VG+   P     PDE  K +LGNK+     V     +RK     T     PPPS E VS+
Sbjct: 1177 VGLQAQPV----PDEIVKKILGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSN 1232

Query: 757  SSEDDSGTDREEEGSVSQRSTPVKMTDAGDSAKVT 791
              + D+  +     S++  ++P +  D   +  +T
Sbjct: 1233 GYKGDTTPNLRLLCSITGGTSPAQWEDITGTTPLT 1267


>gi|32479521 dishevelled 1 [Homo sapiens]
          Length = 670

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 7/61 (11%)

Query: 729 KSNREEAVL-------QRKTAASAPPPPSEEAVSSSSEDDSGTDREEEGSVSQRSTPVKM 781
           + NREEA          R+     PP  +  A+SS  E  S  D +E+GS S+ S+  + 
Sbjct: 150 RRNREEAARTNGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQ 209

Query: 782 T 782
           +
Sbjct: 210 S 210


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,306,168
Number of Sequences: 37866
Number of extensions: 1584149
Number of successful extensions: 5706
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 5586
Number of HSP's gapped (non-prelim): 145
length of query: 907
length of database: 18,247,518
effective HSP length: 111
effective length of query: 796
effective length of database: 14,044,392
effective search space: 11179336032
effective search space used: 11179336032
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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