BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7661580 WD repeat domain, phosphoinositide interacting 2 isoform a [Homo sapiens] (454 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7661580 WD repeat domain, phosphoinositide interacting 2 isof... 908 0.0 gi|75677329 WD repeat domain, phosphoinositide interacting 2 iso... 877 0.0 gi|54111428 WD repeat domain, phosphoinositide interacting 2 iso... 862 0.0 gi|75677331 WD repeat domain, phosphoinositide interacting 2 iso... 831 0.0 gi|75677340 WD repeat domain, phosphoinositide interacting 2 iso... 740 0.0 gi|157388939 WD repeat domain, phosphoinositide interacting 1 [H... 474 e-134 gi|122939167 WDR45-like [Homo sapiens] 129 5e-30 gi|71483646 WD repeat domain 45 isoform 2 [Homo sapiens] 96 5e-20 gi|47059042 WD repeat domain 45 isoform 1 [Homo sapiens] 96 7e-20 gi|21071067 TBP-associated factor 5 [Homo sapiens] 50 4e-06 gi|186928847 cirhin [Homo sapiens] 42 0.001 gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 38 0.017 gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 38 0.022 gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 38 0.022 gi|153218631 breast carcinoma amplified sequence 3 isoform 1 [Ho... 37 0.028 gi|153218595 breast carcinoma amplified sequence 3 isoform 2 [Ho... 37 0.028 gi|32189425 WD repeat domain 69 [Homo sapiens] 37 0.028 gi|26665869 WD repeat domain 51B [Homo sapiens] 35 0.14 gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1... 34 0.24 gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 34 0.24 gi|14150171 THO complex 3 [Homo sapiens] 34 0.24 gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo ... 33 0.53 gi|13376840 WD repeat domain 61 [Homo sapiens] 33 0.70 gi|148528998 Dmx-like 1 [Homo sapiens] 33 0.70 gi|157739942 gemin 5 [Homo sapiens] 32 0.91 gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [... 32 0.91 gi|38569484 kinesin family member 21A [Homo sapiens] 32 1.6 gi|56550086 WD repeat and HMG-box DNA binding protein 1 isoform ... 32 1.6 gi|94400919 WD repeat domain 90 [Homo sapiens] 32 1.6 gi|21541824 transducin-like enhancer protein 1 [Homo sapiens] 31 2.0 >gi|7661580 WD repeat domain, phosphoinositide interacting 2 isoform a [Homo sapiens] Length = 454 Score = 908 bits (2346), Expect = 0.0 Identities = 454/454 (100%), Positives = 454/454 (100%) Query: 1 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS 60 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS Sbjct: 1 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS 60 Query: 61 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 120 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL Sbjct: 61 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 120 Query: 121 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 180 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT Sbjct: 121 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 180 Query: 181 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 240 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE Sbjct: 181 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 240 Query: 241 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 300 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM Sbjct: 241 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 300 Query: 301 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 360 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD Sbjct: 301 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 360 Query: 361 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT 420 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT Sbjct: 361 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT 420 Query: 421 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 454 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD Sbjct: 421 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 454 >gi|75677329 WD repeat domain, phosphoinositide interacting 2 isoform c [Homo sapiens] Length = 443 Score = 877 bits (2266), Expect = 0.0 Identities = 443/454 (97%), Positives = 443/454 (97%), Gaps = 11/454 (2%) Query: 1 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS 60 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS Sbjct: 1 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS 60 Query: 61 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 120 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL Sbjct: 61 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 120 Query: 121 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 180 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT Sbjct: 121 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 180 Query: 181 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 240 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE Sbjct: 181 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 240 Query: 241 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 300 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM Sbjct: 241 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 300 Query: 301 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 360 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD Sbjct: 301 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 360 Query: 361 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT 420 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK AYT Sbjct: 361 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK-----------AYT 409 Query: 421 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 454 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD Sbjct: 410 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 443 >gi|54111428 WD repeat domain, phosphoinositide interacting 2 isoform b [Homo sapiens] Length = 436 Score = 862 bits (2227), Expect = 0.0 Identities = 436/454 (96%), Positives = 436/454 (96%), Gaps = 18/454 (3%) Query: 1 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS 60 MNLASQSGEAGAGQLLFANFNQDNT SLAVGSKSGYKFFSLSS Sbjct: 1 MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSS 42 Query: 61 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 120 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL Sbjct: 43 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 102 Query: 121 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 180 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT Sbjct: 103 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 162 Query: 181 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 240 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE Sbjct: 163 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 222 Query: 241 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 300 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM Sbjct: 223 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 282 Query: 301 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 360 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD Sbjct: 283 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 342 Query: 361 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT 420 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT Sbjct: 343 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT 402 Query: 421 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 454 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD Sbjct: 403 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 436 >gi|75677331 WD repeat domain, phosphoinositide interacting 2 isoform d [Homo sapiens] Length = 425 Score = 831 bits (2147), Expect = 0.0 Identities = 425/454 (93%), Positives = 425/454 (93%), Gaps = 29/454 (6%) Query: 1 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS 60 MNLASQSGEAGAGQLLFANFNQDNT SLAVGSKSGYKFFSLSS Sbjct: 1 MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSS 42 Query: 61 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 120 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL Sbjct: 43 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 102 Query: 121 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 180 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT Sbjct: 103 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 162 Query: 181 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 240 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE Sbjct: 163 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 222 Query: 241 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 300 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM Sbjct: 223 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 282 Query: 301 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 360 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD Sbjct: 283 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 342 Query: 361 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT 420 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK AYT Sbjct: 343 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK-----------AYT 391 Query: 421 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 454 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD Sbjct: 392 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 425 >gi|75677340 WD repeat domain, phosphoinositide interacting 2 isoform e [Homo sapiens] Length = 384 Score = 740 bits (1910), Expect = 0.0 Identities = 372/383 (97%), Positives = 372/383 (97%), Gaps = 11/383 (2%) Query: 72 DTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIV 131 DTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIV Sbjct: 13 DTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIV 72 Query: 132 CLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTIN 191 CLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTIN Sbjct: 73 CLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTIN 132 Query: 192 LRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSI 251 LRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSI Sbjct: 133 LRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSI 192 Query: 252 CSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVT 311 CSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVT Sbjct: 193 CSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVT 252 Query: 312 EMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMK 371 EMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMK Sbjct: 253 EMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMK 312 Query: 372 QHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACL 431 QHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK AYTDDLGAVGGACL Sbjct: 313 QHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK-----------AYTDDLGAVGGACL 361 Query: 432 EDEASALRLDEDSEHPPMILRTD 454 EDEASALRLDEDSEHPPMILRTD Sbjct: 362 EDEASALRLDEDSEHPPMILRTD 384 >gi|157388939 WD repeat domain, phosphoinositide interacting 1 [Homo sapiens] Length = 446 Score = 474 bits (1219), Expect = e-134 Identities = 242/411 (58%), Positives = 314/411 (76%), Gaps = 7/411 (1%) Query: 44 SLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCH 103 SLA G+K+GYK FSLSSV++L+Q++ + DV IVERLFSSSLV +VS PR++ V H Sbjct: 28 SLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHTKPRQMNVYH 87 Query: 104 FKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCA 163 FKKGTEICNYSYS+ IL+++LNRQRL+VCLEES+YIHNI+DMK+L T+ + P NP GLCA Sbjct: 88 FKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCA 147 Query: 164 LSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEK 223 LSIN+ N YLAYPGS T GE+ ++D +L+ I AH+ LAA+ F+ASG+KLA+ASEK Sbjct: 148 LSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEK 207 Query: 224 GTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEK 283 GTVIRVFS+P+GQKL+EFRRG+KR V+I SL FSMD FL ASSNTETVHIFKLE V Sbjct: 208 GTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNS 267 Query: 284 PPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIP 343 PEEP+TW+GY GK+ MA+T+YLP+QV++M +Q RAFAT RL F G +NIC+L+TIQK+P Sbjct: 268 RPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLP 327 Query: 344 RLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAA 403 RLLV ++ G+LYMYNLDPQ+GGEC L+K H L GS TT E ++ P + Q+Y A Sbjct: 328 RLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGS-GTTEENKENDLR--PSLPQSYAAT 384 Query: 404 AGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASA---LRLDEDSEHPPMIL 451 + + S+ T Y++D GA+ G + + A + LD+++E PP+IL Sbjct: 385 VARPS-ASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIIL 434 >gi|122939167 WDR45-like [Homo sapiens] Length = 344 Score = 129 bits (324), Expect = 5e-30 Identities = 109/363 (30%), Positives = 172/363 (47%), Gaps = 57/363 (15%) Query: 15 LLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVDKLEQIYECTDTE 74 LL+A FNQD+ A G ++G++ ++ + + E+ E + Sbjct: 13 LLYAGFNQDHG------------------CFACGMENGFRVYNTDPLKEKEK-QEFLEG- 52 Query: 75 DVCIVERLFSSSLVAIVS-----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRL 129 V VE LF + +A+V P K+ + K + +S + AVKL R R+ Sbjct: 53 GVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRI 112 Query: 130 IVCLEESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQ 185 +V L+ + + HN + V ET NP GLC L N++N LA+PG+ T G VQ Sbjct: 113 VVVLDSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQ 167 Query: 186 VFDTINLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRG 244 + D + + IPAH+ L+ +A + GT++ATASEKGT+IR+F G + E RRG Sbjct: 168 LVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG 227 Query: 245 VKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTS 304 + +I + F+ D + SS+ TVHIF E K +AS S Sbjct: 228 -SQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS------------LASAS 274 Query: 305 YLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEG 364 +LP + F+ +F+ ++P G IC+ T + ++ ADG Y + +P+ Sbjct: 275 FLP----KYFSSKWSFSKFQVP-SGSPCICAFGT--EPNAVIAICADGSYYKFLFNPK-- 325 Query: 365 GEC 367 GEC Sbjct: 326 GEC 328 >gi|71483646 WD repeat domain 45 isoform 2 [Homo sapiens] Length = 360 Score = 96.3 bits (238), Expect = 5e-20 Identities = 65/220 (29%), Positives = 110/220 (50%), Gaps = 18/220 (8%) Query: 78 IVERLFSSSLVAIVSLKAPRKLKVCHF-----------KKGTEICNYSYSNTILAVKLNR 126 +VE L S+L+A+V + K K + ++++ +L+V++ Sbjct: 53 LVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRH 112 Query: 127 QRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQV 186 ++++ L+ +Y+++ D +T NP GLC L + + L +PG G +Q+ Sbjct: 113 DKIVIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKC-GSLQL 171 Query: 187 FDTINLR-----AANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEF 241 D + + A I AH S +A ++ + GT +A+AS+KGT+IR+F +KL E Sbjct: 172 VDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVEL 231 Query: 242 RRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK 281 RRG C + FS D FL ASS+ TVHIF L+ + Sbjct: 232 RRGTDPATLYC-INFSHDSSFLCASSDKGTVHIFALKDTR 270 >gi|47059042 WD repeat domain 45 isoform 1 [Homo sapiens] Length = 361 Score = 95.9 bits (237), Expect = 7e-20 Identities = 56/177 (31%), Positives = 96/177 (54%), Gaps = 7/177 (3%) Query: 110 ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINND 169 + ++++ +L+V++ ++++ L+ +Y+++ D +T NP GLC L + + Sbjct: 97 VLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLE 156 Query: 170 NCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAFDASGTKLATASEKG 224 L +PG G +Q+ D + + A I AH S +A ++ + GT +A+AS+KG Sbjct: 157 KQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKG 215 Query: 225 TVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK 281 T+IR+F +KL E RRG C + FS D FL ASS+ TVHIF L+ + Sbjct: 216 TLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKGTVHIFALKDTR 271 >gi|21071067 TBP-associated factor 5 [Homo sapiens] Length = 800 Score = 50.1 bits (118), Expect = 4e-06 Identities = 37/144 (25%), Positives = 69/144 (47%), Gaps = 11/144 (7%) Query: 158 PAGLCALSINNDNCYLAYPGSATIGE------VQVFDTINLRAANMIPAHDSPLAALAFD 211 P + A + + NC +P S + V+++D +N + H P+ +L F Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS 678 Query: 212 ASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTET 271 +G LAT + G V+ ++ I G + E + ++CSL FS DG L++ S T Sbjct: 679 PNGRFLATGATDGRVL-LWDIGHGLMVGELKGHTD---TVCSLRFSRDGEILASGSMDNT 734 Query: 272 VHIF-KLETVKEKPPEEPTTWTGY 294 V ++ ++ ++ ++ TT TG+ Sbjct: 735 VRLWDAIKAFEDLETDDFTTATGH 758 >gi|186928847 cirhin [Homo sapiens] Length = 686 Score = 42.0 bits (97), Expect = 0.001 Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 3/96 (3%) Query: 188 DTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEG--QKLFEFRRGV 245 D I+L+ + +PA + F TKL AS +G + + + G + L F+ Sbjct: 423 DNISLKRVSKMPAFLRSALQILFSEDSTKLFVASNQGA-LHIVQLSGGSFKHLHAFQPQS 481 Query: 246 KRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK 281 ++C LA S DG +L+AS + VH++ ++ +K Sbjct: 482 GTVEAMCLLAVSPDGNWLAASGTSAGVHVYNVKQLK 517 Score = 37.0 bits (84), Expect = 0.037 Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 13/147 (8%) Query: 91 VSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRL-IVCLEESLYIHNIRDMKVLH 149 +SLK K+ F + +S +T L V N+ L IV L + H LH Sbjct: 425 ISLKRVSKMPA--FLRSALQILFSEDSTKLFVASNQGALHIVQLSGGSFKH-------LH 475 Query: 150 TIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALA 209 + +C L+++ D +LA S T V V++ L+ +PA++ P+ A+A Sbjct: 476 AFQPQSGTVEAMCLLAVSPDGNWLA--ASGTSAGVHVYNVKQLKLHCTVPAYNFPVTAMA 533 Query: 210 FDASGTKLATASEKGTVIRVFSIPEGQ 236 + L A V +SIP+ Q Sbjct: 534 IAPNTNNLVIAHSDQQVFE-YSIPDKQ 559 Score = 31.2 bits (69), Expect = 2.0 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 2/86 (2%) Query: 182 GEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEF 241 GE+ +D L + A P+ ++A SG++L E G+V ++F I + FE Sbjct: 81 GEIMEYDLQALNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSV-KLFQITPDKIQFE- 138 Query: 242 RRGVKRCVSICSLAFSMDGMFLSASS 267 R ++ I SL++ G ++A S Sbjct: 139 RNFDRQKSRILSLSWHPSGTHIAAGS 164 >gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] Length = 359 Score = 38.1 bits (87), Expect = 0.017 Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 22/151 (14%) Query: 157 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTK 216 +P+G C + DN V+V+D R H + + L+F SG Sbjct: 196 HPSGTCIAAAGMDNT------------VKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNY 243 Query: 217 LATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFK 276 L TAS T +++ + EG+ L+ ++ AFS G + ++ + E V ++K Sbjct: 244 LITASSDST-LKILDLMEGRLLYTLHGHQGPATTV---AFSRTGEYFASGGSDEQVMVWK 299 Query: 277 --LETVKE----KPPEEPTTWTGYFGKVLMA 301 + V K P P T G + ++ Sbjct: 300 SNFDIVDHGEVTKVPRPPATLASSMGNLTVS 330 >gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] Length = 369 Score = 37.7 bits (86), Expect = 0.022 Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 16/120 (13%) Query: 157 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTK 216 +P+G C + DN V+V+D R H + + L+F SG Sbjct: 158 HPSGTCIAAAGMDNT------------VKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNY 205 Query: 217 LATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFK 276 L TAS T +++ + EG+ L+ ++ AFS G + ++ + E V ++K Sbjct: 206 LITASSDST-LKILDLMEGRLLYTLHGHQGPATTV---AFSRTGEYFASGGSDEQVMVWK 261 >gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] Length = 407 Score = 37.7 bits (86), Expect = 0.022 Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 16/120 (13%) Query: 157 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTK 216 +P+G C + DN V+V+D R H + + L+F SG Sbjct: 196 HPSGTCIAAAGMDNT------------VKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNY 243 Query: 217 LATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFK 276 L TAS T +++ + EG+ L+ ++ AFS G + ++ + E V ++K Sbjct: 244 LITASSDST-LKILDLMEGRLLYTLHGHQGPATTV---AFSRTGEYFASGGSDEQVMVWK 299 >gi|153218631 breast carcinoma amplified sequence 3 isoform 1 [Homo sapiens] Length = 928 Score = 37.4 bits (85), Expect = 0.028 Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 13/117 (11%) Query: 180 TIGEVQVFDTINLRAANMI---PAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEG- 235 T+GE QV + + + ++ PAH+ P+ +AF+ SG L T G VF I Sbjct: 326 TVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHP 385 Query: 236 --------QKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKP 284 L+ RG + + FS D ++ S+ T H+F + +P Sbjct: 386 WSSSQCAVHHLYTLHRGETE-AKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQP 441 >gi|153218595 breast carcinoma amplified sequence 3 isoform 2 [Homo sapiens] Length = 913 Score = 37.4 bits (85), Expect = 0.028 Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 13/117 (11%) Query: 180 TIGEVQVFDTINLRAANMI---PAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEG- 235 T+GE QV + + + ++ PAH+ P+ +AF+ SG L T G VF I Sbjct: 326 TVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHP 385 Query: 236 --------QKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKP 284 L+ RG + + FS D ++ S+ T H+F + +P Sbjct: 386 WSSSQCAVHHLYTLHRGETE-AKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQP 441 >gi|32189425 WD repeat domain 69 [Homo sapiens] Length = 415 Score = 37.4 bits (85), Expect = 0.028 Identities = 61/263 (23%), Positives = 106/263 (40%), Gaps = 38/263 (14%) Query: 37 GRRAVVWSLAVGSKSGYKFFSLSSVDKLEQIY-----ECTDT------EDVCIVERLFSS 85 G R VV+++A + G K + S DK +++ +C T E VC+ S Sbjct: 132 GHRNVVYAIAFNNPYGDKI-ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNP-QS 189 Query: 86 SLVAIVSLKAPRKLKVCHFKKGTEICNY-SYSNTILAVKLNRQRLIVCLEESLYIHNIRD 144 +LVA S+ KL + G E+ +S I+++ N + + + D Sbjct: 190 TLVATGSMDTTAKL--WDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD 247 Query: 145 MKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSP 204 + + A + + S N D C L GS +++D N + + HD Sbjct: 248 ADTGRKVNILIGHCAEISSASFNWD-CSLILTGSMD-KTCKLWDATNGKCVATLTGHDDE 305 Query: 205 LAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVS--------ICSLAF 256 + FD +G +ATAS GT R+FS ++C++ I ++F Sbjct: 306 ILDSCFDYTGKLIATASADGTA-RIFS-----------AATRKCIAKLEGHEGEISKISF 353 Query: 257 SMDGMFLSASSNTETVHIFKLET 279 + G L S+ +T I+ +T Sbjct: 354 NPQGNHLLTGSSDKTARIWDAQT 376 >gi|26665869 WD repeat domain 51B [Homo sapiens] Length = 478 Score = 35.0 bits (79), Expect = 0.14 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 8/78 (10%) Query: 200 AHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVK--RCVSICSLAFS 257 AH +P+ ++ F A G LATASE + I+V+S+ + L+ R RC FS Sbjct: 100 AHTAPVRSVDFSADGQFLATASEDKS-IKVWSMYRQRFLYSLYRHTHWVRCAK-----FS 153 Query: 258 MDGMFLSASSNTETVHIF 275 DG + + S +T+ I+ Sbjct: 154 PDGRLIVSCSEDKTIKIW 171 Score = 33.9 bits (76), Expect = 0.31 Identities = 27/117 (23%), Positives = 52/117 (44%), Gaps = 17/117 (14%) Query: 157 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTK 216 NP+G C S +D V+V+D + H + ++F SG Sbjct: 195 NPSGTCIASAGSDQT------------VKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNY 242 Query: 217 LATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDG-MFLSASSNTETV 272 L TAS GT +++ + EG+ ++ + + +++FS G +F S ++T+ + Sbjct: 243 LITASSDGT-LKILDLLEGRLIYTLQ---GHTGPVFTVSFSKGGELFASGGADTQVL 295 Score = 32.3 bits (72), Expect = 0.91 Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 4/77 (5%) Query: 201 HDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDG 260 H + ++ F G LA+AS TV R++ + K EF+ + S+ FS DG Sbjct: 59 HKDVVTSVQFSPHGNLLASASRDRTV-RLWIPDKRGKFSEFKA---HTAPVRSVDFSADG 114 Query: 261 MFLSASSNTETVHIFKL 277 FL+ +S +++ ++ + Sbjct: 115 QFLATASEDKSIKVWSM 131 >gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1 [Homo sapiens] Length = 1129 Score = 34.3 bits (77), Expect = 0.24 Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 6/101 (5%) Query: 184 VQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPE-----GQKL 238 V++ D ++ HD+P+ +L+FD LA+AS G+V RV+ I + L Sbjct: 118 VKIVDVMDSSQQKTFRGHDAPVLSLSFDPKDIFLASASCDGSV-RVWQISDQTCAISWPL 176 Query: 239 FEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLET 279 + V SIC LA+ L A ++V +++ E+ Sbjct: 177 LQKCNDVINAKSICRLAWQPKSGKLLAIPVEKSVKLYRRES 217 >gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo sapiens] Length = 504 Score = 34.3 bits (77), Expect = 0.24 Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 6/102 (5%) Query: 177 GSATI-GEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEG 235 G+ T+ +++++D P H P+ ++AF +G LATA++ +V + + Sbjct: 366 GTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSV----KLWDL 421 Query: 236 QKLFEFRR-GVKRCVSICSLAFSMDGMFLSASSNTETVHIFK 276 +KL F+ + + SL F G +L+ ++I K Sbjct: 422 RKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICK 463 >gi|14150171 THO complex 3 [Homo sapiens] Length = 351 Score = 34.3 bits (77), Expect = 0.24 Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 8/117 (6%) Query: 164 LSINNDN-CYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASE 222 +S NNDN + G+ G + + L+ I AH S + FD G AT S Sbjct: 188 ISWNNDNNMFFLTNGN---GCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSA 244 Query: 223 KGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLET 279 V S+ + +L R + + +L+FS DG L+++S + I ++ET Sbjct: 245 DALV----SLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVET 297 >gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo sapiens] Length = 513 Score = 33.1 bits (74), Expect = 0.53 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 3/80 (3%) Query: 202 DSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGM 261 D + + F LAT ++ G I+V+ I GQ L F R + + L+FS D Sbjct: 264 DDAVLCMCFSRDTEMLATGAQDGK-IKVWKIQSGQCLRRFERAHSK--GVTCLSFSKDSS 320 Query: 262 FLSASSNTETVHIFKLETVK 281 + ++S +T+ I L++ K Sbjct: 321 QILSASFDQTIRIHGLKSGK 340 >gi|13376840 WD repeat domain 61 [Homo sapiens] Length = 305 Score = 32.7 bits (73), Expect = 0.70 Identities = 25/119 (21%), Positives = 52/119 (43%), Gaps = 6/119 (5%) Query: 161 LCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATA 220 + +++ + D YLA A G + +FD + + + H P+ +L F L TA Sbjct: 151 ILSIAYSPDGKYLA--SGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTA 208 Query: 221 SEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLET 279 S+ G I+++ + + ++AF D +SS+ ++V ++ + T Sbjct: 209 SDDG-YIKIYDVQHANLAGTLS---GHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGT 263 Score = 32.0 bits (71), Expect = 1.2 Identities = 41/164 (25%), Positives = 73/164 (44%), Gaps = 18/164 (10%) Query: 205 LAALAFDASGT-KLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFL 263 L ++ D S T +A +S IR++ + G+++ G V +LAFS D +L Sbjct: 65 LGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGP---VDAWTLAFSPDSQYL 121 Query: 264 SASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMA-----STSYLPSQVTEMFNQGR 318 + ++ V+IF +E+ K++ + GK +++ YL S + Sbjct: 122 ATGTHVGKVNIFGVESGKKEYSLDTR------GKFILSIAYSPDGKYLASGAIDGIINIF 175 Query: 319 AFATVRL--PFCGHKNICSLATIQKIPRLLVGAA-DGYLYMYNL 359 AT +L GH T +LLV A+ DGY+ +Y++ Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDV 219 >gi|148528998 Dmx-like 1 [Homo sapiens] Length = 3027 Score = 32.7 bits (73), Expect = 0.70 Identities = 33/141 (23%), Positives = 55/141 (39%), Gaps = 9/141 (6%) Query: 92 SLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTI 151 S+ P CH K + S S+ I L+ VCL ++L + Sbjct: 2826 SMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVA------PANSLV 2879 Query: 152 RETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFD 211 + +G L+ + L G G VFD + + +HDSP+ A+A D Sbjct: 2880 HAFTCHDSGATVLAYAPKHQLLISGGRK--GFTYVFDLCQRQQRQLFQSHDSPVKAVAVD 2937 Query: 212 ASGTKLATASEKGTVIRVFSI 232 + T S +G I+++S+ Sbjct: 2938 PTEEYFVTGSAEGN-IKIWSL 2957 >gi|157739942 gemin 5 [Homo sapiens] Length = 1508 Score = 32.3 bits (72), Expect = 0.91 Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 10/125 (8%) Query: 198 IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSIC---SL 254 +P H +++ A G +A +E G+ I +F IP + + ++ K +I Sbjct: 536 LPVHTE----ISWKADGKIMALGNEDGS-IEIFQIPNLKLICTIQQHHKLVNTISWHHEH 590 Query: 255 AFSMDGMFLSAS-SNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEM 313 + +L AS SN +++ L+TV E PE P T T + + L T+ + S Sbjct: 591 GSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPY-RTLSGHTAKITSVAWSP 649 Query: 314 FNQGR 318 + GR Sbjct: 650 HHDGR 654 >gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [Homo sapiens] Length = 340 Score = 32.3 bits (72), Expect = 0.91 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%) Query: 175 YPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPE 234 + A ++++D + H+S + A+AF +G T S+ T R+F + Sbjct: 199 FVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT-CRLFDLRA 257 Query: 235 GQKLFEFRRGVKRCVSICSLAFSMDGMFLSA 265 Q+L + C I S+AFS G L A Sbjct: 258 DQELLMYSHDNIIC-GITSVAFSRSGRLLLA 287 >gi|38569484 kinesin family member 21A [Homo sapiens] Length = 1661 Score = 31.6 bits (70), Expect = 1.6 Identities = 56/277 (20%), Positives = 106/277 (38%), Gaps = 42/277 (15%) Query: 97 RKLKVCHFKKGTEICNYS-YSNTILAVKLNRQRLIVCLEESLYIH--NIRDM-KVLHTIR 152 R KV + G EI + + N +++VK +V + YI +IRD K + T+ Sbjct: 1354 RTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLT 1413 Query: 153 ETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDA 212 + G T+G+ T A IP+ ++ + +A + Sbjct: 1414 SS----------------------GQVTLGDACSASTSRTVA---IPSGENQINQIALNP 1448 Query: 213 SGTKLATASEKGTVIRVFSIPEGQKLFEF--RRGVKRCVSICSLAFSMDGMFLSASSNTE 270 +GT L AS G +R++ + Q + G C+++ ++ D + S Sbjct: 1449 TGTFLYAAS--GNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQD--LIITGSKDH 1504 Query: 271 TVHIFK-----LETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVT--EMFNQGRAFATV 323 + +F L TV EP + G + + S+ + ++ + Sbjct: 1505 YIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQ 1564 Query: 324 RLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 360 ++P +C+L + P LL G G L ++N+D Sbjct: 1565 QVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMD 1601 >gi|56550086 WD repeat and HMG-box DNA binding protein 1 isoform 2 [Homo sapiens] Length = 1006 Score = 31.6 bits (70), Expect = 1.6 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 6/84 (7%) Query: 201 HDSPLAALAFDASGTKLATASEKGTVIRVFSIPE-----GQKLFEFRRGVKRCVSICSLA 255 HD+P+ +L+FD LA+AS G+V RV+ I + L + V SIC LA Sbjct: 12 HDAPVLSLSFDPKDIFLASASCDGSV-RVWQISDQTCAISWPLLQKCNDVINAKSICRLA 70 Query: 256 FSMDGMFLSASSNTETVHIFKLET 279 + L A ++V +++ E+ Sbjct: 71 WQPKSGKLLAIPVEKSVKLYRRES 94 >gi|94400919 WD repeat domain 90 [Homo sapiens] Length = 1748 Score = 31.6 bits (70), Expect = 1.6 Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Query: 182 GEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEF 241 G + DT++ + +H +P+ ALA + +LAT S+ TV R++ + Q+L++F Sbjct: 680 GHLGFLDTLSRVYHMLARSHTAPVLALAMEQRRGQLATVSQDRTV-RIWDLATLQQLYDF 738 >gi|21541824 transducin-like enhancer protein 1 [Homo sapiens] Length = 770 Score = 31.2 bits (69), Expect = 2.0 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 8/98 (8%) Query: 182 GEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEF 241 G + V+D N H + + GTKL T TV R + + EG++L + Sbjct: 596 GNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTV-RSWDLREGRQLQQH 654 Query: 242 RRGVKRCVSICSLAFSMDGMFLSA---SSNTETVHIFK 276 I SL + G +L+ SSN E +H+ K Sbjct: 655 ----DFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNK 688 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.133 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,355,035 Number of Sequences: 37866 Number of extensions: 743945 Number of successful extensions: 1745 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 21 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 1678 Number of HSP's gapped (non-prelim): 85 length of query: 454 length of database: 18,247,518 effective HSP length: 106 effective length of query: 348 effective length of database: 14,233,722 effective search space: 4953335256 effective search space used: 4953335256 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.