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Search of human proteins with 7657647
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657647 neuronal tropomodulin isoform a [Homo sapiens]
(351 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657647 neuronal tropomodulin isoform a [Homo sapiens] 686 0.0
gi|218931148 neuronal tropomodulin isoform b [Homo sapiens] 598 e-171
gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens] 535 e-152
gi|4507553 tropomodulin 1 [Homo sapiens] 413 e-115
gi|156415984 tropomodulin 4 (muscle) [Homo sapiens] 380 e-105
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 247 1e-65
gi|54607116 leiomodin 3 (fetal) [Homo sapiens] 198 5e-51
gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens] 163 2e-40
gi|5174617 nucleotide-binding oligomerization domain containing ... 62 6e-10
gi|118918429 NOD3 protein [Homo sapiens] 55 1e-07
gi|229577123 t-complex-associated testis expressed 1 [Homo sapiens] 47 3e-05
gi|168986655 hypothetical protein LOC145497 [Homo sapiens] 46 6e-05
gi|169213924 PREDICTED: leucine rich repeat containing 68 [Homo ... 43 4e-04
gi|169214345 PREDICTED: leucine rich repeat containing 68 [Homo ... 43 4e-04
gi|169213302 PREDICTED: leucine rich repeat containing 68 [Homo ... 43 4e-04
gi|11545912 nucleotide-binding oligomerization domain containing... 41 0.001
gi|224586773 hypothetical protein LOC643854 [Homo sapiens] 37 0.027
gi|149274621 centrosomal protein 78kDa isoform a [Homo sapiens] 37 0.027
gi|149274651 centrosomal protein 78kDa isoform b [Homo sapiens] 37 0.027
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 37 0.027
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens] 36 0.059
gi|169646281 coiled-coil domain containing 14 [Homo sapiens] 35 0.077
gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain... 35 0.077
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 35 0.13
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 35 0.13
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 35 0.13
gi|22538457 nuclear receptor coactivator 1 isoform 2 [Homo sapiens] 33 0.38
gi|22538459 nuclear receptor coactivator 1 isoform 3 [Homo sapiens] 33 0.38
gi|22538455 nuclear receptor coactivator 1 isoform 1 [Homo sapiens] 33 0.38
gi|33667040 NLR family, pyrin domain containing 8 [Homo sapiens] 33 0.50
>gi|7657647 neuronal tropomodulin isoform a [Homo sapiens]
Length = 351
Score = 686 bits (1769), Expect = 0.0
Identities = 351/351 (100%), Positives = 351/351 (100%)
Query: 1 MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA 60
MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA
Sbjct: 1 MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA 60
Query: 61 TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE 120
TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE
Sbjct: 61 TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE 120
Query: 121 EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP 180
EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP
Sbjct: 121 EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP 180
Query: 181 NPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSND 240
NPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSND
Sbjct: 181 NPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSND 240
Query: 241 PVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAV 300
PVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAV
Sbjct: 241 PVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAV 300
Query: 301 EMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 351
EMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR
Sbjct: 301 EMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 351
>gi|218931148 neuronal tropomodulin isoform b [Homo sapiens]
Length = 315
Score = 598 bits (1542), Expect = e-171
Identities = 315/351 (89%), Positives = 315/351 (89%), Gaps = 36/351 (10%)
Query: 1 MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA 60
MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA
Sbjct: 1 MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA 60
Query: 61 TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE 120
TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE
Sbjct: 61 TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE 120
Query: 121 EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP 180
EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP
Sbjct: 121 EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP 180
Query: 181 NPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSND 240
NPTNVEISLQQMKANDPSLQEVNLNNIK
Sbjct: 181 NPTNVEISLQQMKANDPSLQEVNLNNIK-------------------------------- 208
Query: 241 PVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAV 300
AFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAV
Sbjct: 209 ----AFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAV 264
Query: 301 EMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 351
EMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR
Sbjct: 265 EMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 315
>gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens]
Length = 352
Score = 535 bits (1377), Expect = e-152
Identities = 267/352 (75%), Positives = 310/352 (88%), Gaps = 1/352 (0%)
Query: 1 MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAA 60
MALPF+K+LEKYK++DEDELLG LSE ELKQLE VLDDLDPE+A+LPAGFRQK+QT K+
Sbjct: 1 MALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKST 60
Query: 61 TGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELE 120
TGPFDREHLL YLEKEALE KDRED+VP+TGEKKG++FIPK+KP++T EEKV+LDPELE
Sbjct: 61 TGPFDREHLLSYLEKEALEHKDREDYVPYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELE 120
Query: 121 EALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKG-GKGPVRNVVKGEKVKPVFEEP 179
EAL SASDTEL DLAA+LG+HNL+ N KF ++ G + NVVKGEK+ PVF+EP
Sbjct: 121 EALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVFDEP 180
Query: 180 PNPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSN 239
PNPTNVE SL++ K ND L EVNLNNIKNIPIPTL++FAKALETNTHVK FSLAATRSN
Sbjct: 181 PNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSN 240
Query: 240 DPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTA 299
DPVA AFA+MLKVNKTL SLN+ESNFITG GILAL++AL++N+TL E+KIDNQRQQLGTA
Sbjct: 241 DPVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAELKIDNQRQQLGTA 300
Query: 300 VEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 351
VE+E+A+MLEEN+ ILKFGYQFT+QGPRTR A AITKNNDLVRK+RVE D +
Sbjct: 301 VELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRVEGDHQ 352
>gi|4507553 tropomodulin 1 [Homo sapiens]
Length = 359
Score = 413 bits (1061), Expect = e-115
Identities = 206/345 (59%), Positives = 276/345 (80%), Gaps = 2/345 (0%)
Query: 3 LPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATG 62
+ +++ELEKY+++DEDE+LG L+EEEL+ LEN LD+LDP++A+LPAG RQKDQT KA TG
Sbjct: 1 MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTG 60
Query: 63 PFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEA 122
PF RE LL +LEK+A E KDRED VP+TGEK+G+V++PK+KP++ E VTL+PELEEA
Sbjct: 61 PFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLES-VTLEPELEEA 119
Query: 123 LASASDTELYDLAAVLGVHNLLNNPKFDEETANNK-GGKGPVRNVVKGEKVKPVFEEPPN 181
LA+ASD EL D+AA+LG+H L++N ++ + +++ K + +V+K + KPV +E PN
Sbjct: 120 LANASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPN 179
Query: 182 PTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDP 241
T+VE +L+++K NDP L+EVNLNNI+NIPIPTL+ +A+AL+ N++VKKFS+ TRSNDP
Sbjct: 180 STDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDP 239
Query: 242 VAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVE 301
VA A A+MLK NK L +LN+ESNFI+G GIL LVEAL N +L E+KIDNQ Q LG VE
Sbjct: 240 VAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVE 299
Query: 302 MEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRV 346
MEI MLE+N+ +LKFGY FT+QGPR R + A+ NNDLVRK+R+
Sbjct: 300 MEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRL 344
>gi|156415984 tropomodulin 4 (muscle) [Homo sapiens]
Length = 345
Score = 380 bits (975), Expect = e-105
Identities = 189/346 (54%), Positives = 271/346 (78%), Gaps = 11/346 (3%)
Query: 5 FQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPF 64
+QKELEKY++IDEDE+L LS EEL+QL+ L ++DPE+ +LPAG RQ+DQT+K+ TGP
Sbjct: 4 YQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPL 63
Query: 65 DREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALA 124
DRE LL YLE++ALE K+R+D VPFTGEKKG+ +I ++ I EE++TL+PELEEALA
Sbjct: 64 DREALLQYLEQQALEVKERDDLVPFTGEKKGKPYIQPKREIPA--EEQITLEPELEEALA 121
Query: 125 SASDTELYDLAAVLGVHNLLNNPKFDE-----ETANNKGGKGPVRNVVKGEKVKPVFEEP 179
A+D E+ D+AA+L ++ L++N ++ + E N +G + +VV+ +K KPV +EP
Sbjct: 122 HATDAEMCDIAAILDMYTLMSNKQYYDALCSGEICNTEG----ISSVVQPDKYKPVPDEP 177
Query: 180 PNPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSN 239
PNPTN+E L+++++ND L+EVNLNNI++IPIP L E +A++ NT+V+ FSL ATRS
Sbjct: 178 PNPTNIEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSG 237
Query: 240 DPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTA 299
DP+A A ADML+ N++L SLNIESNFI+ TG++A+++A++EN TLTE+++DNQRQ G A
Sbjct: 238 DPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDA 297
Query: 300 VEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKR 345
VEME+A +LE+ I++FGY FT+QGPR R A A+T+NN+L R+++
Sbjct: 298 VEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELRRQQK 343
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 247 bits (630), Expect = 1e-65
Identities = 149/370 (40%), Positives = 219/370 (59%), Gaps = 33/370 (8%)
Query: 5 FQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPF 64
+++ L KY++IDEDELL LS EELK+LE L+D++P+ LP G RQK T+K TG F
Sbjct: 6 YRRGLSKYESIDEDELLASLSAEELKELERELEDIEPDRN-LPVGLRQKSLTEKTPTGTF 64
Query: 65 DREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIE----------------TR 108
RE L+ Y EKE+ + ++E GE G+V KE+ E T
Sbjct: 65 SREALMAYWEKESQKLLEKERL----GEC-GKVAEDKEESEEELIFTESNSEVSEEVYTE 119
Query: 109 KEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVK 168
+EE+ + + E EE SD E + G++ +N + + + K K + N+
Sbjct: 120 EEEEESQEEEEEED----SDEEERTIETAKGINGTVNYDSVNSDNSKPKIFKSQIENINL 175
Query: 169 GEKVKPVFEEPP-------NPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKA 221
E P NPT +E +L ++K+NDP EVNLNNI+NI TL FA+A
Sbjct: 176 TNGSNGRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEA 235
Query: 222 LETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKEN 281
L+ NT VK FSLA T ++D A+A A+MLKVN+ +T++N+ESNFITG GILA++ AL+ N
Sbjct: 236 LKDNTVVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHN 295
Query: 282 DTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLV 341
LTE++ NQR +G+ VEMEI ++L+EN+ +L+ GY F GPR + + +T+N D
Sbjct: 296 TVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQ 355
Query: 342 RKKRVEADRR 351
R+KR++ ++
Sbjct: 356 RQKRLQEQKQ 365
>gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
Length = 560
Score = 198 bits (504), Expect = 5e-51
Identities = 135/393 (34%), Positives = 206/393 (52%), Gaps = 55/393 (13%)
Query: 13 KNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMY 72
+ I+EDE+L LS EELK+L++ ++ + P+ + LP G QKDQT K TG F+ + L+ Y
Sbjct: 16 EEINEDEILANLSAEELKELQSEMEVMAPDPS-LPVGMIQKDQTDKPPTGNFNHKSLVDY 74
Query: 73 ----------LEKEAL-------EQKDREDFVPFTGEKKGRVFIPKEKP----IETRKEE 111
LE+E + E+K +E+ K KEK + ++E
Sbjct: 75 MYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRES 134
Query: 112 KVT-----LDPELEEALASASDTELYDLA-------------AVLGVHNLLNN------- 146
K + D E EE D E D A + N NN
Sbjct: 135 KGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDK 194
Query: 147 --------PKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPS 198
P+ E++ P + + +K N T+++ SL++++ NDP
Sbjct: 195 AFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPD 254
Query: 199 LQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTS 258
++E+NLNNI+NIP L +F A++ N H+K FSLA +++ VA A A+ML+ N+++T+
Sbjct: 255 MKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLRENRSITT 314
Query: 259 LNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFG 318
LNIESNFITG GI+A++ L+ N+TLTE++ NQR LG EMEIA++L+ N+ +LK G
Sbjct: 315 LNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKMG 374
Query: 319 YQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 351
Y F GPR V +T+N D R+KR E ++
Sbjct: 375 YHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQ 407
>gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens]
Length = 600
Score = 163 bits (413), Expect = 2e-40
Identities = 94/212 (44%), Positives = 130/212 (61%), Gaps = 6/212 (2%)
Query: 145 NNPKFDEETANNKGGKGPVRNVVKGEKVKPV-----FEEPPNPTNVEISLQQMKANDPSL 199
N P ++E ++ K P + G KP EE P+ + L+++K NDP +
Sbjct: 274 NEPLHEKEAKDDSKTKTPEKQTPSGP-TKPSEGPAKVEEEAAPSIFDEPLERVKNNDPEM 332
Query: 200 QEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSL 259
EVN+NN I L F +ALE NT VK F+LA TR++D VA A A MLK NKT+TSL
Sbjct: 333 TEVNVNNSDCITNEILVRFTEALEFNTVVKLFALANTRADDHVAFAIAIMLKANKTITSL 392
Query: 260 NIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGY 319
N++SN ITG GILA+ AL +N+TLTE++ NQR G EMEIA++L+EN+ +LK GY
Sbjct: 393 NLDSNHITGKGILAIFRALLQNNTLTELRFHNQRHICGGKTEMEIAKLLKENTTLLKLGY 452
Query: 320 QFTKQGPRTRVAAAITKNNDLVRKKRVEADRR 351
F GPR V +++N D R+KR++ R+
Sbjct: 453 HFELAGPRMTVTNLLSRNMDKQRQKRLQEQRQ 484
Score = 62.8 bits (151), Expect = 5e-10
Identities = 46/159 (28%), Positives = 77/159 (48%), Gaps = 18/159 (11%)
Query: 16 DEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEK 75
D D LL LS EE+++LE LD +DP+ ++ P G RQ++QT+K +TG ++RE +L + EK
Sbjct: 16 DIDSLLETLSPEEMEELEKELDVVDPDGSV-PVGLRQRNQTEKQSTGVYNREAMLNFCEK 74
Query: 76 EALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDLA 135
E + RE + + + K +ET+ + K + + + + DL
Sbjct: 75 ETKKLMQRE------------MSMDESKQVETKTDAKNGEERGRDASKKALGPRRDSDLG 122
Query: 136 AVLGVHNLLNNPKFDEETANNKGGKGP-----VRNVVKG 169
L + D + A K G+ P +R + KG
Sbjct: 123 KEPKRGGLKKSFSRDRDEAGGKSGEKPKEEKIIRGIDKG 161
>gi|5174617 nucleotide-binding oligomerization domain containing 1
[Homo sapiens]
Length = 953
Score = 62.4 bits (150), Expect = 6e-10
Identities = 43/123 (34%), Positives = 66/123 (53%), Gaps = 7/123 (5%)
Query: 195 NDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNK 254
N PSL ++L + I + A+AL+ NT ++ L ND VA + A+MLKVN+
Sbjct: 838 NHPSLTTLSLAS-NGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQ 896
Query: 255 TLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRI 314
TL L + N IT G L +AL+ N +TEI ++ G ++ E A++ E+ RI
Sbjct: 897 TLKHLWLIQNQITAKGTAQLADALQSNTGITEICLN------GNLIKPEEAKVYEDEKRI 950
Query: 315 LKF 317
+ F
Sbjct: 951 ICF 953
Score = 34.7 bits (78), Expect = 0.13
Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 4/100 (4%)
Query: 216 REFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALV 275
+ FA+AL + + SLA+ + + A L+ N +L L + N + +L
Sbjct: 830 KAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLA 889
Query: 276 EALKENDTLTEI-KIDNQRQQLGTAVEMEIAQMLEENSRI 314
E LK N TL + I NQ GTA ++A L+ N+ I
Sbjct: 890 EMLKVNQTLKHLWLIQNQITAKGTA---QLADALQSNTGI 926
>gi|118918429 NOD3 protein [Homo sapiens]
Length = 1065
Score = 54.7 bits (130), Expect = 1e-07
Identities = 43/153 (28%), Positives = 70/153 (45%), Gaps = 9/153 (5%)
Query: 192 MKANDPSLQEVNL--NNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFADM 249
+ D +Q+++L N I N L A++L N + L A A AD
Sbjct: 661 LSGKDCRIQKISLAENQISNKGAKAL---ARSLLVNRSLTSLDLRGNSIGPQGAKALADA 717
Query: 250 LKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLE 309
LK+N+TLTSL+++ N + G ++ EAL N TL+ + + Q+ +G +A L+
Sbjct: 718 LKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHL--QKNSIGPMGAQRMADALK 775
Query: 310 ENSRI--LKFGYQFTKQGPRTRVAAAITKNNDL 340
+N + L F G +A A+ N L
Sbjct: 776 QNRSLKELMFSSNSIGDGGAKALAEALKVNQGL 808
Score = 51.6 bits (122), Expect = 1e-06
Identities = 45/156 (28%), Positives = 74/156 (47%), Gaps = 7/156 (4%)
Query: 188 SLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFA 247
S+ + A++ +L ++L P+ R A AL+ N +K+ ++ D A A A
Sbjct: 741 SMAEALASNRTLSMLHLQKNSIGPMGAQR-MADALKQNRSLKELMFSSNSIGDGGAKALA 799
Query: 248 DMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQM 307
+ LKVN+ L SL+++SN I+ G+ AL+ AL N TL + + + + IA
Sbjct: 800 EALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSL--RENSISPEGAQAIAHA 857
Query: 308 LEENSRILKFGYQ---FTKQGPRTRVAAAITKNNDL 340
L NS + QG R +A A+ +N L
Sbjct: 858 LCANSTLKNLDLTANLLHDQGARA-IAVAVRENRTL 892
Score = 48.5 bits (114), Expect = 9e-06
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 2/107 (1%)
Query: 219 AKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEAL 278
A AL N+ +K L A +D A A A ++ N+TLTSL+++ NFI AL +AL
Sbjct: 855 AHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQAL 914
Query: 279 KENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQG 325
+ N +LT +D Q +G +A+ L+ N+ + Q G
Sbjct: 915 QLNRSLT--SLDLQENAIGDDGACAVARALKVNTALTALYLQVASIG 959
Score = 42.7 bits (99), Expect = 5e-04
Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 4/123 (3%)
Query: 220 KALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALK 279
+AL+ N + L D A A A LKVN LT+L ++ I +G L EAL
Sbjct: 912 QALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALA 971
Query: 280 ENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQG--PRTRVAAAITKN 337
N TL EI +D + +G A +A L+ NS + + Q G +A A++ N
Sbjct: 972 VNRTL-EI-LDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAICIATALSGN 1029
Query: 338 NDL 340
+ L
Sbjct: 1030 HRL 1032
Score = 42.0 bits (97), Expect = 8e-04
Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Query: 219 AKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEAL 278
A+AL+ NT + L A + L VN+TL L++ N I G AL AL
Sbjct: 939 ARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANAL 998
Query: 279 KENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQ 320
K N +L + + Q LG + IA L N R+ Q
Sbjct: 999 KVNSSLRRLNL--QENSLGMDGAICIATALSGNHRLQHINLQ 1038
Score = 39.7 bits (91), Expect = 0.004
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 221 ALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKE 280
AL TN + SL + A A A L N TL +L++ +N + G A+ A++E
Sbjct: 829 ALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRE 888
Query: 281 NDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQ 320
N TLT + + Q G A + Q L+ N + Q
Sbjct: 889 NRTLTSLHLQWNFIQAGAA--QALGQALQLNRSLTSLDLQ 926
Score = 37.0 bits (84), Expect = 0.027
Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
Query: 216 REFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALV 275
R A A+ N + L A A L++N++LTSL+++ N I G A+
Sbjct: 880 RAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVA 939
Query: 276 EALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEEN 311
ALK N LT + + Q +G + + + L N
Sbjct: 940 RALKVNTALTALYL--QVASIGASGAQVLGEALAVN 973
>gi|229577123 t-complex-associated testis expressed 1 [Homo sapiens]
Length = 501
Score = 46.6 bits (109), Expect = 3e-05
Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Query: 188 SLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFA 247
SL A++ +L +NL + I + A AL+TN + L ++P A +
Sbjct: 353 SLAHALAHNTNLISLNLR-LNCIEDEGGQALAHALQTNKCLTTLHLGGNELSEPTATLLS 411
Query: 248 DMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQM 307
+L +N TLTS+N+ N I G L+E + +N TL E D + + E I Q
Sbjct: 412 QVLAINTTLTSINLSCNHIGLDGGKQLLEGMSDNKTLLE--FDLRLSDVAQESEYLIGQA 469
Query: 308 LEEN 311
L N
Sbjct: 470 LYAN 473
Score = 43.1 bits (100), Expect = 4e-04
Identities = 36/148 (24%), Positives = 66/148 (44%), Gaps = 5/148 (3%)
Query: 199 LQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTS 258
L+ +NL N + P + A AL NT++ +L D A A L+ NK LT+
Sbjct: 336 LRVLNLAN-NQVRAPGAQSLAHALAHNTNLISLNLRLNCIEDEGGQALAHALQTNKCLTT 394
Query: 259 LNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFG 318
L++ N ++ L + L N TLT I + +G ++ + + +N +L+F
Sbjct: 395 LHLGGNELSEPTATLLSQVLAINTTLTSINL--SCNHIGLDGGKQLLEGMSDNKTLLEFD 452
Query: 319 YQFT--KQGPRTRVAAAITKNNDLVRKK 344
+ + Q + A+ N + R++
Sbjct: 453 LRLSDVAQESEYLIGQALYANREAARQR 480
>gi|168986655 hypothetical protein LOC145497 [Homo sapiens]
Length = 488
Score = 45.8 bits (107), Expect = 6e-05
Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Query: 220 KALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALK 279
+AL TN +KK L+ + +D ML +N LTSL++ N G +AL L+
Sbjct: 212 QALSTNYQIKKLDLSHNQFSDVGGEHLGQMLAINVGLTSLDLSWNNFHTRGAVALCNGLR 271
Query: 280 ENDTLTEIKIDNQRQQLGTAVEMEIAQMLEEN 311
N TLT K+D G V + + ++L N
Sbjct: 272 GNVTLT--KLDLSMNGFGNEVALALGEVLRLN 301
Score = 44.7 bits (104), Expect = 1e-04
Identities = 43/143 (30%), Positives = 63/143 (44%), Gaps = 9/143 (6%)
Query: 170 EKVKPVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVK 229
EKVKP E + T++EI + K +E+ L K + + + F + +E +
Sbjct: 56 EKVKPAREN--SETDLEIEDDE-KFFTTGQKELYLEACKLMGVVPVSYFIRNMEESYVNL 112
Query: 230 KFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKI 289
R +AIA N +T L +E N I G+L+LVE L+EN L E+ I
Sbjct: 113 NHHGLGPRGTKAIAIALVS----NMAVTKLELEDNCIMEEGVLSLVEMLQENYYLQEMNI 168
Query: 290 DNQRQQLGTAVEMEIAQMLEENS 312
N LG I+ E NS
Sbjct: 169 SN--NHLGLEGARIISDFFERNS 189
Score = 32.0 bits (71), Expect = 0.85
Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 4/97 (4%)
Query: 222 LETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKEN 281
L N + L+ + A+A + L+ N TLT L++ N LAL E L+ N
Sbjct: 242 LAINVGLTSLDLSWNNFHTRGAVALCNGLRGNVTLTKLDLSMNGFGNEVALALGEVLRLN 301
Query: 282 DTLTEIKIDNQRQQLGTAVEMEIAQMLEENS--RILK 316
L + +D +G +I++ LE N R+LK
Sbjct: 302 RCL--VYLDIGGNDIGNEGASKISKGLESNESLRVLK 336
>gi|169213924 PREDICTED: leucine rich repeat containing 68 [Homo
sapiens]
Length = 625
Score = 43.1 bits (100), Expect = 4e-04
Identities = 31/117 (26%), Positives = 58/117 (49%), Gaps = 4/117 (3%)
Query: 197 PSLQEVNLNNIKNIPIPT--LREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNK 254
P Q + N+ + PI +R L +N V + LA+T+ A+A A+ + +
Sbjct: 343 PHTQSLETLNLGHNPIGNEGVRHLKNGLISNRSVLRLGLASTKLTCEGAVAVAEFIAESP 402
Query: 255 TLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQ--RQQLGTAVEMEIAQMLE 309
L L++ N I G++AL ALK N +L + +D + ++ + + +E + A + E
Sbjct: 403 RLLRLDLRENEIKTGGLMALSLALKVNHSLLRLDLDREPKKEAVKSFIETQKALLAE 459
Score = 32.7 bits (73), Expect = 0.50
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Query: 198 SLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIA-FADMLKVNKTL 256
SL ++L N P L A AL+ N ++++ LA + N A ++LK N +L
Sbjct: 233 SLAVLHLENASLSGRP-LMLLATALKMNMNLRELYLADNKLNGLQDSAQLGNLLKFNCSL 291
Query: 257 TSLNIESNFITGTGILALVEALKE--NDTLTEIKIDNQRQQLGTA 299
L++ +N + +G+ + E LKE +T + +NQ G A
Sbjct: 292 QILDLRNNHVLDSGLAYICEGLKEQRKGLVTLVLWNNQLTHTGMA 336
>gi|169214345 PREDICTED: leucine rich repeat containing 68 [Homo
sapiens]
Length = 625
Score = 43.1 bits (100), Expect = 4e-04
Identities = 31/117 (26%), Positives = 58/117 (49%), Gaps = 4/117 (3%)
Query: 197 PSLQEVNLNNIKNIPIPT--LREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNK 254
P Q + N+ + PI +R L +N V + LA+T+ A+A A+ + +
Sbjct: 343 PHTQSLETLNLGHNPIGNEGVRHLKNGLISNRSVLRLGLASTKLTCEGAVAVAEFIAESP 402
Query: 255 TLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQ--RQQLGTAVEMEIAQMLE 309
L L++ N I G++AL ALK N +L + +D + ++ + + +E + A + E
Sbjct: 403 RLLRLDLRENEIKTGGLMALSLALKVNHSLLRLDLDREPKKEAVKSFIETQKALLAE 459
Score = 32.7 bits (73), Expect = 0.50
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Query: 198 SLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIA-FADMLKVNKTL 256
SL ++L N P L A AL+ N ++++ LA + N A ++LK N +L
Sbjct: 233 SLAVLHLENASLSGRP-LMLLATALKMNMNLRELYLADNKLNGLQDSAQLGNLLKFNCSL 291
Query: 257 TSLNIESNFITGTGILALVEALKE--NDTLTEIKIDNQRQQLGTA 299
L++ +N + +G+ + E LKE +T + +NQ G A
Sbjct: 292 QILDLRNNHVLDSGLAYICEGLKEQRKGLVTLVLWNNQLTHTGMA 336
>gi|169213302 PREDICTED: leucine rich repeat containing 68 [Homo
sapiens]
Length = 625
Score = 43.1 bits (100), Expect = 4e-04
Identities = 31/117 (26%), Positives = 58/117 (49%), Gaps = 4/117 (3%)
Query: 197 PSLQEVNLNNIKNIPIPT--LREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNK 254
P Q + N+ + PI +R L +N V + LA+T+ A+A A+ + +
Sbjct: 343 PHTQSLETLNLGHNPIGNEGVRHLKNGLISNRSVLRLGLASTKLTCEGAVAVAEFIAESP 402
Query: 255 TLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQ--RQQLGTAVEMEIAQMLE 309
L L++ N I G++AL ALK N +L + +D + ++ + + +E + A + E
Sbjct: 403 RLLRLDLRENEIKTGGLMALSLALKVNHSLLRLDLDREPKKEAVKSFIETQKALLAE 459
Score = 32.7 bits (73), Expect = 0.50
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Query: 198 SLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIA-FADMLKVNKTL 256
SL ++L N P L A AL+ N ++++ LA + N A ++LK N +L
Sbjct: 233 SLAVLHLENASLSGRP-LMLLATALKMNMNLRELYLADNKLNGLQDSAQLGNLLKFNCSL 291
Query: 257 TSLNIESNFITGTGILALVEALKE--NDTLTEIKIDNQRQQLGTA 299
L++ +N + +G+ + E LKE +T + +NQ G A
Sbjct: 292 QILDLRNNHVLDSGLAYICEGLKEQRKGLVTLVLWNNQLTHTGMA 336
>gi|11545912 nucleotide-binding oligomerization domain containing 2
[Homo sapiens]
Length = 1040
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 219 AKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEAL 278
A+AL + ++ SL A A A ML N L L +E N + G+ +L E L
Sbjct: 920 AEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLAEGL 979
Query: 279 KENDTLTEIKIDNQ-RQQLGTAVEMEIAQMLEENSRILK 316
K+N +L +K+ N LG + Q LE N IL+
Sbjct: 980 KKNSSLKILKLSNNCITYLGAEA---LLQALERNDTILE 1015
>gi|224586773 hypothetical protein LOC643854 [Homo sapiens]
Length = 777
Score = 37.0 bits (84), Expect = 0.027
Identities = 74/327 (22%), Positives = 135/327 (41%), Gaps = 56/327 (17%)
Query: 10 EKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHL 69
EK K +++ L+ K E E ++E+ L+D E A + +K + + E
Sbjct: 88 EKCKLLEKFSLIQK--EYEGYEVESSLEDASFEKAAAEEARSLEATCEKLSRSNSELEDE 145
Query: 70 LMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDT 129
++ LEK+ E+K + ++ + K I++ ++E +L ++ EA
Sbjct: 146 ILCLEKDLKEEKSKH-------SQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTF 198
Query: 130 ELYDLAAVLGVHNLLNNPK---------FDEETANNKGGKGPVRNVVKGEKVKPVFEEPP 180
++ + + + + LN F +E KG V + K K FE+
Sbjct: 199 KMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKG------QVSELNKQKITFEDS- 251
Query: 181 NPTNVEISLQQMKANDPSLQEVNLNNIKNIP--IPTLREFAKALETNT------HVKKFS 232
++ +Q+ ND N+IK + +P +++ A LE +T +K S
Sbjct: 252 -----KVHAEQV-LNDKE------NHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNS 299
Query: 233 LAATRSN--DPVAIAFADML---KVNKTLTSLNIESNFITGTGILALVEALKENDTLTEI 287
+N DP A ++ K+N +L SL E N I I+ L E K + LTE
Sbjct: 300 QWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHI----IIQLSEVDKTKEELTEH 355
Query: 288 KIDNQRQQLGTAVEMEIAQMLEENSRI 314
+ Q QQ +++ E EN ++
Sbjct: 356 IKNLQTQQ--ASLQSENIYFESENQKL 380
>gi|149274621 centrosomal protein 78kDa isoform a [Homo sapiens]
Length = 722
Score = 37.0 bits (84), Expect = 0.027
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 236 TRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQ 295
T D A AFAD L + L +L+++ +T G AL+EAL+ N TL + I +
Sbjct: 238 TLIGDLGACAFADSLSEDLWLRALDLQQCGLTNEGAKALLEALETNTTLVVLDI-RKNPL 296
Query: 296 LGTAVEMEIAQMLEENSRILKFGYQF 321
+ ++ + + + +N R K YQ+
Sbjct: 297 IDHSMMKAVIKKVLQNGRSAKSEYQW 322
>gi|149274651 centrosomal protein 78kDa isoform b [Homo sapiens]
Length = 706
Score = 37.0 bits (84), Expect = 0.027
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 236 TRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQ 295
T D A AFAD L + L +L+++ +T G AL+EAL+ N TL + I +
Sbjct: 238 TLIGDLGACAFADSLSEDLWLRALDLQQCGLTNEGAKALLEALETNTTLVVLDI-RKNPL 296
Query: 296 LGTAVEMEIAQMLEENSRILKFGYQF 321
+ ++ + + + +N R K YQ+
Sbjct: 297 IDHSMMKAVIKKVLQNGRSAKSEYQW 322
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 37.0 bits (84), Expect = 0.027
Identities = 53/219 (24%), Positives = 85/219 (38%), Gaps = 34/219 (15%)
Query: 6 QKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFD 65
Q+ELE+ K +EL +++EE + E L+ E A +++Q Q+ A
Sbjct: 504 QEELERQKR---EELAQRVAEERTTRREEESRRLEAEQAR-----EKEEQLQRQA----- 550
Query: 66 REHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALAS 125
E L E+ Q+ +E+ E+ RV +EK + ++E++ LEE +
Sbjct: 551 EERALREREEAERAQRQKEEEAR-VREEAERVRQEREKHFQREEQERLERKKRLEEIMKR 609
Query: 126 ASDTELYD------------LAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVK 173
TE D A+ G + P N K P +VV + K
Sbjct: 610 TRRTEATDKKTSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVGSP--HVVTSHQSK 667
Query: 174 PVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKNIPI 212
E P+ +Q N S+Q N I N+PI
Sbjct: 668 VTVESTPDLE------KQPNENGVSVQNENFEEIINLPI 700
>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
Length = 5120
Score = 35.8 bits (81), Expect = 0.059
Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 5/125 (4%)
Query: 74 EKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYD 133
EK EQ++R+ EK+ + +E+ +EEK+T D +++AL E
Sbjct: 2276 EKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQER 2335
Query: 134 LAAVLGVHNL---LNNPKFDEETAN--NKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEIS 188
LA + L L K ++E KG +GP++ +K + ++ P T V++
Sbjct: 2336 LAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVK 2395
Query: 189 LQQMK 193
++ ++
Sbjct: 2396 METIE 2400
>gi|169646281 coiled-coil domain containing 14 [Homo sapiens]
Length = 912
Score = 35.4 bits (80), Expect = 0.077
Identities = 48/208 (23%), Positives = 87/208 (41%), Gaps = 26/208 (12%)
Query: 3 LPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATG 62
+ Q +LE+ ++ ELL +EE LK +EN D E+ + F+ KDQT
Sbjct: 491 MSLQNQLEE--SLKSQELLQSKNEELLKVIENQKD----ENKKFSSIFKDKDQTILENKQ 544
Query: 63 PFDREHLLMYLE-KEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEE 121
+D E + +E +EAL F T EK+ ++ + +++ +VT EL
Sbjct: 545 QYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLR----QRDAEVTRLRELTR 600
Query: 122 ALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPN 181
L ++ L DL+ ++A K G ++++ + + P
Sbjct: 601 TLQTSMAKLLSDLSV---------------DSARCKPGNNLTKSLLNIHDKQLQHDPAPA 645
Query: 182 PTNVEISLQQMKANDPSLQEVNLNNIKN 209
T++ L +++ N L+ IKN
Sbjct: 646 HTSIMSYLNKLETNYSFTHSEPLSTIKN 673
>gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain
and proline-rich containing [Homo sapiens]
Length = 1435
Score = 35.4 bits (80), Expect = 0.077
Identities = 19/65 (29%), Positives = 34/65 (52%)
Query: 220 KALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALK 279
+AL TN ++ ++ D A A L+VN L S+ + N + G+L + +AL+
Sbjct: 603 RALATNPNLTALDISGNAMGDAGAKLLAKALRVNSRLRSVVWDRNHTSALGLLDVAQALE 662
Query: 280 ENDTL 284
+N +L
Sbjct: 663 QNHSL 667
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 34.7 bits (78), Expect = 0.13
Identities = 44/194 (22%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 16 DEDELLGKLSEEELKQL-ENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLE 74
+ ++ L K SEEE+ E+ DD + ES +D ++K + +RE LE
Sbjct: 520 ESEDDLNKESEEEVGPTKESEEDDSEKES--------DEDCSEKQSEDGSEREFEENGLE 571
Query: 75 KEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDL 134
K+ E+ ++ +K+ + E EKV + E SD + +
Sbjct: 572 KDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEE 631
Query: 135 AAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKA 194
V + ++ K DEE A+ KG + + +G+ + +FEE + + + ++++
Sbjct: 632 DTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVED 691
Query: 195 NDPSLQEVNLNNIK 208
D L E + +N K
Sbjct: 692 ADEKLFEDDDSNEK 705
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 34.7 bits (78), Expect = 0.13
Identities = 44/194 (22%), Positives = 84/194 (43%), Gaps = 9/194 (4%)
Query: 16 DEDELLGKLSEEELKQL-ENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLE 74
+ ++ L K SEEE+ E+ DD + ES +D ++K + +RE LE
Sbjct: 520 ESEDDLNKESEEEVGPTKESEEDDSEKES--------DEDCSEKQSEDGSEREFEENGLE 571
Query: 75 KEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDL 134
K+ E+ ++ +K+ + E EKV + E SD + +
Sbjct: 572 KDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEE 631
Query: 135 AAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKA 194
V + ++ K DEE A+ KG + + +G+ + +FEE + + + ++++
Sbjct: 632 DTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVED 691
Query: 195 NDPSLQEVNLNNIK 208
D L E + +N K
Sbjct: 692 ADEKLFEDDDSNEK 705
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 34.7 bits (78), Expect = 0.13
Identities = 31/124 (25%), Positives = 63/124 (50%), Gaps = 14/124 (11%)
Query: 6 QKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFD 65
Q+E+E K E+E ++ +EEL++L+ + ++ E + F++ DQ QK D
Sbjct: 687 QQEIELQKKRQEEETFLRV-QEELQRLKELNNNEKAEKFQI---FQELDQLQKEK----D 738
Query: 66 REHLLMYLEKEALEQKDREDFVPFT------GEKKGRVFIPKEKPIETRKEEKVTLDPEL 119
++ + LEK+ LE++++E + EK+ + + + ++ +EEK L+
Sbjct: 739 EQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIR 798
Query: 120 EEAL 123
E L
Sbjct: 799 ESLL 802
>gi|22538457 nuclear receptor coactivator 1 isoform 2 [Homo sapiens]
Length = 1399
Score = 33.1 bits (74), Expect = 0.38
Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 40/193 (20%)
Query: 28 ELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALE----QKDR 83
E +++ + + +S +LPA Q A P R + L LE EA++ Q
Sbjct: 832 ETDRMDGAVTSVTIKSEILPASL------QSATARPTSRLNRLPELELEAIDNQFGQPGT 885
Query: 84 EDFVPFTGEKKGRVFIPKEKP----------------IETRKEEKVTLDPELEEALASAS 127
D +P+T + K + +E R +EK L+ +L L+
Sbjct: 886 GDQIPWTNNTVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLE-QLVSFLSGKD 944
Query: 128 DTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKP--VFEEPPNPTNV 185
+TEL +L LG+ L+ GG + ++ P + EE PN +
Sbjct: 945 ETELAELDRALGIDKLVQG-----------GGLDVLSERFPPQQATPPLIMEERPNLYSQ 993
Query: 186 EISLQQMKANDPS 198
S AN PS
Sbjct: 994 PYSSPSPTANLPS 1006
>gi|22538459 nuclear receptor coactivator 1 isoform 3 [Homo sapiens]
Length = 1440
Score = 33.1 bits (74), Expect = 0.38
Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 40/193 (20%)
Query: 28 ELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALE----QKDR 83
E +++ + + +S +LPA Q A P R + L LE EA++ Q
Sbjct: 832 ETDRMDGAVTSVTIKSEILPASL------QSATARPTSRLNRLPELELEAIDNQFGQPGT 885
Query: 84 EDFVPFTGEKKGRVFIPKEKP----------------IETRKEEKVTLDPELEEALASAS 127
D +P+T + K + +E R +EK L+ +L L+
Sbjct: 886 GDQIPWTNNTVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLE-QLVSFLSGKD 944
Query: 128 DTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKP--VFEEPPNPTNV 185
+TEL +L LG+ L+ GG + ++ P + EE PN +
Sbjct: 945 ETELAELDRALGIDKLVQG-----------GGLDVLSERFPPQQATPPLIMEERPNLYSQ 993
Query: 186 EISLQQMKANDPS 198
S AN PS
Sbjct: 994 PYSSPSPTANLPS 1006
>gi|22538455 nuclear receptor coactivator 1 isoform 1 [Homo sapiens]
Length = 1441
Score = 33.1 bits (74), Expect = 0.38
Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 40/193 (20%)
Query: 28 ELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALE----QKDR 83
E +++ + + +S +LPA Q A P R + L LE EA++ Q
Sbjct: 832 ETDRMDGAVTSVTIKSEILPASL------QSATARPTSRLNRLPELELEAIDNQFGQPGT 885
Query: 84 EDFVPFTGEKKGRVFIPKEKP----------------IETRKEEKVTLDPELEEALASAS 127
D +P+T + K + +E R +EK L+ +L L+
Sbjct: 886 GDQIPWTNNTVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLE-QLVSFLSGKD 944
Query: 128 DTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKP--VFEEPPNPTNV 185
+TEL +L LG+ L+ GG + ++ P + EE PN +
Sbjct: 945 ETELAELDRALGIDKLVQG-----------GGLDVLSERFPPQQATPPLIMEERPNLYSQ 993
Query: 186 EISLQQMKANDPS 198
S AN PS
Sbjct: 994 PYSSPSPTANLPS 1006
>gi|33667040 NLR family, pyrin domain containing 8 [Homo sapiens]
Length = 1048
Score = 32.7 bits (73), Expect = 0.50
Identities = 23/64 (35%), Positives = 38/64 (59%), Gaps = 5/64 (7%)
Query: 253 NKTLTSLNIESNFITGTGILALVEALKEND-TLTEIKIDNQRQQLGTAVEME-IAQMLEE 310
NKTL SL++ N + G++ L EALK D TL ++++N L T++ + +A ML +
Sbjct: 923 NKTLKSLDLSFNSLKDDGVILLCEALKNPDCTLQILELEN---CLFTSICCQAMASMLRK 979
Query: 311 NSRI 314
N +
Sbjct: 980 NQHL 983
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,705,180
Number of Sequences: 37866
Number of extensions: 591201
Number of successful extensions: 2028
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 70
Number of HSP's that attempted gapping in prelim test: 1901
Number of HSP's gapped (non-prelim): 177
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.