Search of human proteins with 7657587

Search of human proteins with 7657587

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657587 solute carrier family 6 (neurotransmitter
transporter, GABA), member 11 [Homo sapiens]
         (632 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657587 solute carrier family 6 (neurotransmitter transporter...  1323   0.0  
gi|21361581 solute carrier family 6 (neurotransmitter transporte...   882   0.0  
gi|171184408 solute carrier family 6 (neurotransmitter transport...   843   0.0  
gi|171184406 solute carrier family 6 (neurotransmitter transport...   843   0.0  
gi|171184404 solute carrier family 6 (neurotransmitter transport...   843   0.0  
gi|197276623 solute carrier family 6 (neurotransmitter transport...   781   0.0  
gi|54607094 solute carrier family 6 (neurotransmitter transporte...   781   0.0  
gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapi...   690   0.0  
gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sa...   672   0.0  
gi|188528618 solute carrier family 6 (neurotransmitter transport...   639   0.0  
gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sa...   597   e-171
gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo sap...   518   e-147
gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo sap...   518   e-147
gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo sap...   518   e-147
gi|92859670 solute carrier family 6 (neurotransmitter transporte...   517   e-146
gi|4557046 solute carrier family 6 member 2 [Homo sapiens]            513   e-145
gi|134304856 solute carrier family 6, member 7 [Homo sapiens]         513   e-145
gi|4507043 solute carrier family 6 member 4 [Homo sapiens]            509   e-144
gi|4507041 solute carrier family 6 (neurotransmitter transporter...   493   e-139
gi|6005715 solute carrier family 6 (amino acid transporter), mem...   461   e-130
gi|51468073 solute carrier family 6, member 19 [Homo sapiens]         362   e-100
gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo s...   346   3e-95
gi|194018524 solute carrier family 6, member 18 [Homo sapiens]        340   2e-93
gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo s...   290   2e-78
gi|58219014 solute carrier family 6, member 17 [Homo sapiens]         274   2e-73
gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo s...   259   7e-69
gi|197276625 solute carrier family 6 (neurotransmitter transport...   234   2e-61
gi|55749589 solute carrier family 6, member 16 [Homo sapiens]         199   5e-51
gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo ...   190   3e-48
gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo s...   176   6e-44

>gi|7657587 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 11 [Homo sapiens]
          Length = 632

 Score = 1323 bits (3423), Expect = 0.0
 Identities = 632/632 (100%), Positives = 632/632 (100%)

Query: 1   MTAEKALPLGNGKAAEEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFV 60
           MTAEKALPLGNGKAAEEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFV
Sbjct: 1   MTAEKALPLGNGKAAEEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFV 60

Query: 61  LSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGIT 120
           LSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGIT
Sbjct: 61  LSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGIT 120

Query: 121 CWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENC 180
           CWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENC
Sbjct: 121 CWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENC 180

Query: 181 VEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICY 240
           VEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICY
Sbjct: 181 VEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICY 240

Query: 241 FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWV 300
           FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWV
Sbjct: 241 FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWV 300

Query: 301 DAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMA 360
           DAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMA
Sbjct: 301 DAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMA 360

Query: 361 YEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVT 420
           YEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVT
Sbjct: 361 YEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVT 420

Query: 421 AVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVA 480
           AVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVA
Sbjct: 421 AVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVA 480

Query: 481 IFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKY 540
           IFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKY
Sbjct: 481 IFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKY 540

Query: 541 NNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKL 600
           NNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKL
Sbjct: 541 NNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKL 600

Query: 601 GVSPRMVTVNDCDAKLKSDGTIAAITEKETHF 632
           GVSPRMVTVNDCDAKLKSDGTIAAITEKETHF
Sbjct: 601 GVSPRMVTVNDCDAKLKSDGTIAAITEKETHF 632


>gi|21361581 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 13 [Homo sapiens]
          Length = 602

 Score =  882 bits (2278), Expect = 0.0
 Identities = 410/579 (70%), Positives = 480/579 (82%), Gaps = 4/579 (0%)

Query: 27  GCSSGGAAPARHPRV--KRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNG 84
           G +S G     +P +  K +    ERGHWNNK+EFVLSVAGEIIGLGNVWRFPYLCYKNG
Sbjct: 7   GTTSNGETKPVYPVMEKKEEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNG 66

Query: 85  GGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLN 144
           GGAF IPY+VF   CGIPVF LETALGQ+TS+GG+T WRK+CP+FEGIGYA+Q+I   LN
Sbjct: 67  GGAFFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLN 126

Query: 145 VYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVM 204
           VYYII+LAWA+FYL + FT +LPW  C HEWNTE+C+EFQK N S   + + +NATSPV+
Sbjct: 127 VYYIIVLAWALFYLFSSFTIDLPWGGCYHEWNTEHCMEFQKTNGS--LNGTSENATSPVI 184

Query: 205 EFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIM 264
           EFWE RVL ISDGI+H+G LRWELALCLL AW ICYFCIWKG KSTGKVVY TATFPY+M
Sbjct: 185 EFWERRVLKISDGIQHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLM 244

Query: 265 LLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYN 324
           L++LLIRGVTLPGA++GI+FYLYP+L+RL DPQVW+DAGTQIFFS+AICLGCLTALGSYN
Sbjct: 245 LVVLLIRGVTLPGAAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYN 304

Query: 325 NYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPK 384
            Y+NNCYRDCI LC LNSGTSFVAGFAIFS+LGFM+ EQGVPI+EVAESGPGLAFIAYP+
Sbjct: 305 KYHNNCYRDCIALCFLNSGTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPR 364

Query: 385 AVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALS 444
           AV M+P SPLWA  FF M++ LGLDSQFVCVESLVTA+VDMYP VFR+  RRE+LIL +S
Sbjct: 365 AVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVS 424

Query: 445 VISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMI 504
           V+S+ +GL+MLTEGGMY+FQLFD YAASGMCLLFVAIFE +C+ WVYG+ RFYDNIEDMI
Sbjct: 425 VVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMI 484

Query: 505 GYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLC 564
           GYRP  LIK+CW+ +TP +C   F+F LIKY PL YN  YTYP WG  +GWL+ALSSM+C
Sbjct: 485 GYRPWPLIKYCWLFLTPAVCTATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVC 544

Query: 565 IPLWICITVWKTEGTLPEKLQKLTTPSTDLKMRGKLGVS 603
           IP W    +   +G   E++++L  P+ DL  R   G S
Sbjct: 545 IPAWSLYRLGTLKGPFRERIRQLMCPAEDLPQRNPAGPS 583


>gi|171184408 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  843 bits (2179), Expect = 0.0
 Identities = 389/549 (70%), Positives = 461/549 (83%), Gaps = 3/549 (0%)

Query: 47  VHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFL 106
           V +RG W NK+EFVLSVAGEIIGLGNVWRFPYLCYKNGGGAF IPY +FF  CGIPVFFL
Sbjct: 33  VKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFL 92

Query: 107 ETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTEL 166
           E ALGQ+TS+G +T WRK+CPLF+GIG A+ VIE++LNVYYIIILAWA+FYL + FT+EL
Sbjct: 93  EVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSEL 152

Query: 167 PWATCGHEWNTENCVEFQKLNVSNYSHVS-LQNATSPVMEFWEHRVLAISDGIEHIGNLR 225
           PW TC + WNTE+C +F  LN S    V+  +N TSPVMEFWE RVL I+ GI  +G+LR
Sbjct: 153 PWTTCNNFWNTEHCTDF--LNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLR 210

Query: 226 WELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFY 285
           WELALCLL AW ICYFCIWKG KSTGKVVY TATFPY+ML+ILLIRGVTLPGA +GI +Y
Sbjct: 211 WELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYY 270

Query: 286 LYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTS 345
           L PDL RL DPQVW+DAGTQIFFS+AIC GCLTALGSYN Y+NNCY+DCI LC LNS TS
Sbjct: 271 LKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATS 330

Query: 346 FVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIF 405
           FVAGF +FS+LGFM+ EQGVPI+EVAESGPGLAFIA+PKAVTMMPLS LW+ LFF+MLIF
Sbjct: 331 FVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIF 390

Query: 406 LGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQL 465
           LGLDSQFVCVE LVTA +DM+P+  R+  RRELLIL ++V+ Y +GL ++TEGGMYIFQL
Sbjct: 391 LGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQL 450

Query: 466 FDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICA 525
           FD YA+SG+CLLF+++FE +CI WVYG++RFYDNIEDMIGYRP  L+K  W+ +TPG+C 
Sbjct: 451 FDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCL 510

Query: 526 GIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQ 585
             F+F L KY PLKYNN+Y YP WGY IGW +ALSSM+C+PL++ IT+ KT G   ++L+
Sbjct: 511 ATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLR 570

Query: 586 KLTTPSTDL 594
           +L TP + L
Sbjct: 571 QLITPDSSL 579


>gi|171184406 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  843 bits (2179), Expect = 0.0
 Identities = 389/549 (70%), Positives = 461/549 (83%), Gaps = 3/549 (0%)

Query: 47  VHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFL 106
           V +RG W NK+EFVLSVAGEIIGLGNVWRFPYLCYKNGGGAF IPY +FF  CGIPVFFL
Sbjct: 33  VKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFL 92

Query: 107 ETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTEL 166
           E ALGQ+TS+G +T WRK+CPLF+GIG A+ VIE++LNVYYIIILAWA+FYL + FT+EL
Sbjct: 93  EVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSEL 152

Query: 167 PWATCGHEWNTENCVEFQKLNVSNYSHVS-LQNATSPVMEFWEHRVLAISDGIEHIGNLR 225
           PW TC + WNTE+C +F  LN S    V+  +N TSPVMEFWE RVL I+ GI  +G+LR
Sbjct: 153 PWTTCNNFWNTEHCTDF--LNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLR 210

Query: 226 WELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFY 285
           WELALCLL AW ICYFCIWKG KSTGKVVY TATFPY+ML+ILLIRGVTLPGA +GI +Y
Sbjct: 211 WELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYY 270

Query: 286 LYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTS 345
           L PDL RL DPQVW+DAGTQIFFS+AIC GCLTALGSYN Y+NNCY+DCI LC LNS TS
Sbjct: 271 LKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATS 330

Query: 346 FVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIF 405
           FVAGF +FS+LGFM+ EQGVPI+EVAESGPGLAFIA+PKAVTMMPLS LW+ LFF+MLIF
Sbjct: 331 FVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIF 390

Query: 406 LGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQL 465
           LGLDSQFVCVE LVTA +DM+P+  R+  RRELLIL ++V+ Y +GL ++TEGGMYIFQL
Sbjct: 391 LGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQL 450

Query: 466 FDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICA 525
           FD YA+SG+CLLF+++FE +CI WVYG++RFYDNIEDMIGYRP  L+K  W+ +TPG+C 
Sbjct: 451 FDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCL 510

Query: 526 GIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQ 585
             F+F L KY PLKYNN+Y YP WGY IGW +ALSSM+C+PL++ IT+ KT G   ++L+
Sbjct: 511 ATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLR 570

Query: 586 KLTTPSTDL 594
           +L TP + L
Sbjct: 571 QLITPDSSL 579


>gi|171184404 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  843 bits (2179), Expect = 0.0
 Identities = 389/549 (70%), Positives = 461/549 (83%), Gaps = 3/549 (0%)

Query: 47  VHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFL 106
           V +RG W NK+EFVLSVAGEIIGLGNVWRFPYLCYKNGGGAF IPY +FF  CGIPVFFL
Sbjct: 33  VKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFL 92

Query: 107 ETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTEL 166
           E ALGQ+TS+G +T WRK+CPLF+GIG A+ VIE++LNVYYIIILAWA+FYL + FT+EL
Sbjct: 93  EVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSEL 152

Query: 167 PWATCGHEWNTENCVEFQKLNVSNYSHVS-LQNATSPVMEFWEHRVLAISDGIEHIGNLR 225
           PW TC + WNTE+C +F  LN S    V+  +N TSPVMEFWE RVL I+ GI  +G+LR
Sbjct: 153 PWTTCNNFWNTEHCTDF--LNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLR 210

Query: 226 WELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFY 285
           WELALCLL AW ICYFCIWKG KSTGKVVY TATFPY+ML+ILLIRGVTLPGA +GI +Y
Sbjct: 211 WELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYY 270

Query: 286 LYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTS 345
           L PDL RL DPQVW+DAGTQIFFS+AIC GCLTALGSYN Y+NNCY+DCI LC LNS TS
Sbjct: 271 LKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATS 330

Query: 346 FVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIF 405
           FVAGF +FS+LGFM+ EQGVPI+EVAESGPGLAFIA+PKAVTMMPLS LW+ LFF+MLIF
Sbjct: 331 FVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIF 390

Query: 406 LGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQL 465
           LGLDSQFVCVE LVTA +DM+P+  R+  RRELLIL ++V+ Y +GL ++TEGGMYIFQL
Sbjct: 391 LGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQL 450

Query: 466 FDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICA 525
           FD YA+SG+CLLF+++FE +CI WVYG++RFYDNIEDMIGYRP  L+K  W+ +TPG+C 
Sbjct: 451 FDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCL 510

Query: 526 GIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQ 585
             F+F L KY PLKYNN+Y YP WGY IGW +ALSSM+C+PL++ IT+ KT G   ++L+
Sbjct: 511 ATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLR 570

Query: 586 KLTTPSTDL 594
           +L TP + L
Sbjct: 571 QLITPDSSL 579


>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score =  781 bits (2017), Expect = 0.0
 Identities = 360/562 (64%), Positives = 437/562 (77%), Gaps = 1/562 (0%)

Query: 30  SGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFL 89
           S G +P   P  + +    +R  W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAFL
Sbjct: 21  SPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFL 80

Query: 90  IPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYII 149
           IPY +F    G+PVFFLE  +GQ+TSEGGITCW K+CPLF GIGYA+ VI + LNVYYI+
Sbjct: 81  IPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIV 140

Query: 150 ILAWAIFYLSNCFTTELPWATCGHEWNTENCVE-FQKLNVSNYSHVSLQNATSPVMEFWE 208
           ILAWA +YL   F  ELPWA C H WNT +C+E   + N S +  +S  N TSPV+EFWE
Sbjct: 141 ILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200

Query: 209 HRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLIL 268
             VL++S GI+H G+L+W+LALCLL  W +C+FCIWKG +STGKVVY TATFP+ MLL+L
Sbjct: 201 RNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVL 260

Query: 269 LIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNN 328
           L+RG+TLPGA  GIKFYLYPD++RL DPQVW+DAGTQIFFSYAICLG +T+LGSYN Y  
Sbjct: 261 LVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKY 320

Query: 329 NCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTM 388
           N YRDC++L CLNSGTSFV+GFAIFS+LGFMA EQGV IA+VAESGPGLAFIAYPKAVTM
Sbjct: 321 NSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTM 380

Query: 389 MPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISY 448
           MPL   W+ LFF+ML+ LGLDSQFV VE  +T++VD+YP   R+GYRRE+ I  +  ISY
Sbjct: 381 MPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISY 440

Query: 449 FLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRP 508
            LGL M+TEGGMY+FQLFD YAASG+CLL+VA FEC  I W+YG +  YD IEDMIGYRP
Sbjct: 441 LLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRP 500

Query: 509 PSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLW 568
              +K+ W ++TP +C G FIF L+KY PL YN  Y YP W  G+GW +ALSSMLC+PL 
Sbjct: 501 GPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLV 560

Query: 569 ICITVWKTEGTLPEKLQKLTTP 590
           I I + +TEG    +++ L TP
Sbjct: 561 IVIRLCQTEGPFLVRVKYLLTP 582


>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score =  781 bits (2017), Expect = 0.0
 Identities = 360/562 (64%), Positives = 437/562 (77%), Gaps = 1/562 (0%)

Query: 30  SGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFL 89
           S G +P   P  + +    +R  W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAFL
Sbjct: 21  SPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFL 80

Query: 90  IPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYII 149
           IPY +F    G+PVFFLE  +GQ+TSEGGITCW K+CPLF GIGYA+ VI + LNVYYI+
Sbjct: 81  IPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIV 140

Query: 150 ILAWAIFYLSNCFTTELPWATCGHEWNTENCVE-FQKLNVSNYSHVSLQNATSPVMEFWE 208
           ILAWA +YL   F  ELPWA C H WNT +C+E   + N S +  +S  N TSPV+EFWE
Sbjct: 141 ILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200

Query: 209 HRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLIL 268
             VL++S GI+H G+L+W+LALCLL  W +C+FCIWKG +STGKVVY TATFP+ MLL+L
Sbjct: 201 RNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVL 260

Query: 269 LIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNN 328
           L+RG+TLPGA  GIKFYLYPD++RL DPQVW+DAGTQIFFSYAICLG +T+LGSYN Y  
Sbjct: 261 LVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKY 320

Query: 329 NCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTM 388
           N YRDC++L CLNSGTSFV+GFAIFS+LGFMA EQGV IA+VAESGPGLAFIAYPKAVTM
Sbjct: 321 NSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTM 380

Query: 389 MPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISY 448
           MPL   W+ LFF+ML+ LGLDSQFV VE  +T++VD+YP   R+GYRRE+ I  +  ISY
Sbjct: 381 MPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISY 440

Query: 449 FLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRP 508
            LGL M+TEGGMY+FQLFD YAASG+CLL+VA FEC  I W+YG +  YD IEDMIGYRP
Sbjct: 441 LLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRP 500

Query: 509 PSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLW 568
              +K+ W ++TP +C G FIF L+KY PL YN  Y YP W  G+GW +ALSSMLC+PL 
Sbjct: 501 GPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLV 560

Query: 569 ICITVWKTEGTLPEKLQKLTTP 590
           I I + +TEG    +++ L TP
Sbjct: 561 IVIRLCQTEGPFLVRVKYLLTP 582


>gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo
           sapiens]
          Length = 635

 Score =  690 bits (1781), Expect = 0.0
 Identities = 322/575 (56%), Positives = 415/575 (72%), Gaps = 8/575 (1%)

Query: 23  APG-GGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCY 81
           APG  G  + G  P          AV  R  W  +++F++S  G  +GLGNVWRFPYLCY
Sbjct: 24  APGPDGAPAKGDGPVGLGTPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCY 83

Query: 82  KNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEA 141
           KNGGG FLIPYV+  +  GIP+FFLE +LGQF   G I  W  +CPLF+G+GYA+ VI  
Sbjct: 84  KNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWN-ICPLFKGLGYASMVIVF 142

Query: 142 HLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQK------LNVSNYSHVS 195
           + N YYI++LAW  +YL   FTT LPWATCGH WNT +CVE  +       +++N +   
Sbjct: 143 YCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQ 202

Query: 196 LQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVY 255
           L +  SPV+EFWE++VL +S G+E  G L WE+ LCLLA W + YFC+WKG KSTGK+VY
Sbjct: 203 LADRRSPVIEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVY 262

Query: 256 VTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLG 315
            TATFPY++L++LL+RGV LPGA +GI +YL PD S+L  PQVW+DAGTQIFFSYAI LG
Sbjct: 263 FTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLG 322

Query: 316 CLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGP 375
            LTALGSYN +NNNCY+D I+L  +NSGTSF AGF +FS+LGFMA EQGV I++VAESGP
Sbjct: 323 ALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMAAEQGVHISKVAESGP 382

Query: 376 GLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR 435
           GLAFIAYP+AVT+MP++PLWA LFF ML+ LGLDSQFV VE  +T ++D+ P  +   ++
Sbjct: 383 GLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQ 442

Query: 436 RELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNR 495
           RE+ +     + + + L M+T+GGMY+FQLFD Y+ASG  LL+ A +EC+ + WVYG++R
Sbjct: 443 REISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADR 502

Query: 496 FYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGW 555
           F D+I  MIGYRP   +KWCW   TP +C GIFIF ++ Y+PL YNN Y YP WG  +GW
Sbjct: 503 FMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGW 562

Query: 556 LMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTP 590
             ALSSMLC+PL +   + + +GT+ E+ Q LT P
Sbjct: 563 AFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQP 597


>gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo
           sapiens]
          Length = 625

 Score =  672 bits (1733), Expect = 0.0
 Identities = 317/575 (55%), Positives = 408/575 (70%), Gaps = 18/575 (3%)

Query: 23  APG-GGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCY 81
           APG  G  + G  P          AV  R  W  +++F++S  G  +GLGNVWRFPYLCY
Sbjct: 24  APGPDGAPAKGDGPVGLGTPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCY 83

Query: 82  KNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEA 141
           KNGGG FLIPYV+  +  GIP+FFLE +LGQF   G I  W  +CPLF+G+GYA+ VI  
Sbjct: 84  KNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWN-ICPLFKGLGYASMVIVF 142

Query: 142 HLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQK------LNVSNYSHVS 195
           + N YYI++LAW  +YL   FTT LPWATCGH WNT +CVE  +       +++N +   
Sbjct: 143 YCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQ 202

Query: 196 LQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVY 255
           L +  SPV+EFWE++VL +S G+E  G L WE+ LCLLA W + YFC+WKG KSTGK+VY
Sbjct: 203 LADRRSPVIEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVY 262

Query: 256 VTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLG 315
            TATFPY++L++LL+RGV LPGA +GI +YL PD S+L  PQVW+DAGTQIFFSYAI LG
Sbjct: 263 FTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLG 322

Query: 316 CLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGP 375
            LTALGSYN +NNNCY          +GTSF AGF +FS+LGFMA EQGV I++VAESGP
Sbjct: 323 ALTALGSYNRFNNNCY----------NGTSFFAGFVVFSILGFMAAEQGVHISKVAESGP 372

Query: 376 GLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR 435
           GLAFIAYP+AVT+MP++PLWA LFF ML+ LGLDSQFV VE  +T ++D+ P  +   ++
Sbjct: 373 GLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQ 432

Query: 436 RELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNR 495
           RE+ +     + + + L M+T+GGMY+FQLFD Y+ASG  LL+ A +EC+ + WVYG++R
Sbjct: 433 REISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADR 492

Query: 496 FYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGW 555
           F D+I  MIGYRP   +KWCW   TP +C GIFIF ++ Y+PL YNN Y YP WG  +GW
Sbjct: 493 FMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGW 552

Query: 556 LMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTP 590
             ALSSMLC+PL +   + + +GT+ E+ Q LT P
Sbjct: 553 AFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQP 587


>gi|188528618 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 1 [Homo sapiens]
          Length = 599

 Score =  639 bits (1649), Expect = 0.0
 Identities = 302/553 (54%), Positives = 395/553 (71%), Gaps = 11/553 (1%)

Query: 42  KRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGI 101
           K+   + +R  W  + +F++S  G  IGLGNVWRFPYLC KNGGGAFLIPY +  I  G+
Sbjct: 36  KKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGV 95

Query: 102 PVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNC 161
           P+F LE +LGQ+TS GG+  W K+ P+F+G+G A  V+   LN+YYI+I++WAI+YL N 
Sbjct: 96  PLFLLECSLGQYTSIGGLGVW-KLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNS 154

Query: 162 FTTELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHI 221
           FTT LPW  C + WNT+ C        SNYS V+  N TS V+EFWE  +  ++DG++  
Sbjct: 155 FTTTLPWKQCDNPWNTDRCF-------SNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKP 207

Query: 222 GNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEG 281
           G +RW LA+ L  AW + YFCIWKG   TGKVVY +AT+PYIML+IL  RGVTLPGA EG
Sbjct: 208 GQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEG 267

Query: 282 IKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLN 341
           I FY+ P+  +LSD +VW+DA TQIFFSY + LG L ALGSYN+++NN YRD I++CC+N
Sbjct: 268 ILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCIN 327

Query: 342 SGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFM 401
           S TS  AGF IFS++GFMA+     IA+VA SGPGLAF+AYP+AVT +P+SPLWA LFF 
Sbjct: 328 SCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFS 387

Query: 402 MLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMY 461
           ML+ LG+DSQF  VE  +TA+VD YP++ R   RREL I A+ +ISY +GL  +T+GG+Y
Sbjct: 388 MLLMLGIDSQFCTVEGFITALVDEYPRLLRN--RRELFIAAVCIISYLIGLSNITQGGIY 445

Query: 462 IFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTP 521
           +F+LFD Y+ASGM LLF+  FEC+ I W YG NRFYDNI++M+G RP    K CW   TP
Sbjct: 446 VFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTP 505

Query: 522 GICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLP 581
            I AG+FIF  ++  PL   N Y +P WG G+GWLMALSSM+ IP ++       +G+L 
Sbjct: 506 IIVAGVFIFSAVQMTPLTMGN-YVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLK 564

Query: 582 EKLQKLTTPSTDL 594
           +++Q +  PS D+
Sbjct: 565 QRIQVMVQPSEDI 577


>gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo
           sapiens]
          Length = 520

 Score =  597 bits (1540), Expect = e-171
 Identities = 274/480 (57%), Positives = 356/480 (74%), Gaps = 7/480 (1%)

Query: 117 GGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWN 176
           G I  W  +CPLF+G+GYA+ VI  + N YYI++LAW  +YL   FTT LPWATCGH WN
Sbjct: 4   GSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWN 62

Query: 177 TENCVEFQK------LNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELAL 230
           T +CVE  +       +++N +   L +  SPV+EFWE++VL +S G+E  G L WE+ L
Sbjct: 63  TPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGGLEVPGALNWEVTL 122

Query: 231 CLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDL 290
           CLLA W + YFC+WKG KSTGK+VY TATFPY++L++LL+RGV LPGA +GI +YL PD 
Sbjct: 123 CLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDW 182

Query: 291 SRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGF 350
           S+L  PQVW+DAGTQIFFSYAI LG LTALGSYN +NNNCY+D I+L  +NSGTSF AGF
Sbjct: 183 SKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGF 242

Query: 351 AIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDS 410
            +FS+LGFMA EQGV I++VAESGPGLAFIAYP+AVT+MP++PLWA LFF ML+ LGLDS
Sbjct: 243 VVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDS 302

Query: 411 QFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYA 470
           QFV VE  +T ++D+ P  +   ++RE+ +     + + + L M+T+GGMY+FQLFD Y+
Sbjct: 303 QFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYS 362

Query: 471 ASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIF 530
           ASG  LL+ A +EC+ + WVYG++RF D+I  MIGYRP   +KWCW   TP +C GIFIF
Sbjct: 363 ASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIF 422

Query: 531 FLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQKLTTP 590
            ++ Y+PL YNN Y YP WG  +GW  ALSSMLC+PL +   + + +GT+ E+ Q LT P
Sbjct: 423 NVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQP 482


>gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo
           sapiens]
          Length = 706

 Score =  518 bits (1334), Expect = e-147
 Identities = 254/580 (43%), Positives = 374/580 (64%), Gaps = 23/580 (3%)

Query: 29  SSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAF 88
           +  GA P+     KRD+ + +RG+W N++EFVL+  G  +GLGNVWRFPYLCY+NGGGAF
Sbjct: 82  AQNGAVPSE--ATKRDQNL-KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAF 138

Query: 89  LIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYI 148
           + PY +  I CGIP+FF+E + GQF S+G +  WR + P+F+G+GY   V+  ++ +YY 
Sbjct: 139 MFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYN 197

Query: 149 IILAWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLN-----------VSNYSHV--- 194
           +++  A +Y  +  T  LPWA C + WNT +C      +            SN SH+   
Sbjct: 198 VVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNH 257

Query: 195 SLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVV 254
           SLQ  TSP  E+W   VL +SD I + G +R  L  CL  +W + + C+ +G KS+GKVV
Sbjct: 258 SLQR-TSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVV 316

Query: 255 YVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICL 314
           Y TATFPY++L IL +RGVTL GA +GI +YL P   ++ + +VW DA +QIF+S     
Sbjct: 317 YFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAW 376

Query: 315 GCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESG 374
           G L  + SYN ++NNCYRD +++   N  TS  AGF IFS+LGFMA   GV ++ VA+ G
Sbjct: 377 GGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHG 436

Query: 375 PGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGY 434
           PGLAF+AYP+A+T++P+SPLW+ LFF MLI LGL +QF  +E+LVTA+VD     +    
Sbjct: 437 PGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWIL-Q 495

Query: 435 RRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSN 494
           ++  + L ++V  + LG+ + ++ G+Y   L D+YAAS   L+ ++   C+ I ++YG  
Sbjct: 496 KKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHR 554

Query: 495 RFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIG 554
            ++ +I+ M+G+ PP   + CW  ++P I   I +F +I+Y+P+ YN+ Y YP W   IG
Sbjct: 555 NYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIG 613

Query: 555 WLMALSSMLCIPLWICITVWKTEG-TLPEKLQKLTTPSTD 593
           +LMALSS+LCIPL+    + +T+G TL ++L+  T PS D
Sbjct: 614 FLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRD 653


>gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo
           sapiens]
          Length = 633

 Score =  518 bits (1333), Expect = e-147
 Identities = 254/577 (44%), Positives = 373/577 (64%), Gaps = 23/577 (3%)

Query: 32  GAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIP 91
           GA P+     KRD+ + +RG+W N++EFVL+  G  +GLGNVWRFPYLCY+NGGGAF+ P
Sbjct: 12  GAVPSE--ATKRDQNL-KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFP 68

Query: 92  YVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIIL 151
           Y +  I CGIP+FF+E + GQF S+G +  WR + P+F+G+GY   V+  ++ +YY +++
Sbjct: 69  YFIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVI 127

Query: 152 AWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLN-----------VSNYSHV---SLQ 197
             A +Y  +  T  LPWA C + WNT +C      +            SN SH+   SLQ
Sbjct: 128 CIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQ 187

Query: 198 NATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVT 257
             TSP  E+W   VL +SD I + G +R  L  CL  +W + + C+ +G KS+GKVVY T
Sbjct: 188 R-TSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFT 246

Query: 258 ATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCL 317
           ATFPY++L IL +RGVTL GA +GI +YL P   ++ + +VW DA +QIF+S     G L
Sbjct: 247 ATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGL 306

Query: 318 TALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGL 377
             + SYN ++NNCYRD +++   N  TS  AGF IFS+LGFMA   GV ++ VA+ GPGL
Sbjct: 307 ITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGL 366

Query: 378 AFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRE 437
           AF+AYP+A+T++P+SPLW+ LFF MLI LGL +QF  +E+LVTA+VD     +    ++ 
Sbjct: 367 AFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWIL-QKKT 425

Query: 438 LLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFY 497
            + L ++V  + LG+ + ++ G+Y   L D+YAAS   L+ ++   C+ I ++YG   ++
Sbjct: 426 YVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYF 484

Query: 498 DNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLM 557
            +I+ M+G+ PP   + CW  ++P I   I +F +I+Y+P+ YN+ Y YP W   IG+LM
Sbjct: 485 QDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLM 543

Query: 558 ALSSMLCIPLWICITVWKTEG-TLPEKLQKLTTPSTD 593
           ALSS+LCIPL+    + +T+G TL ++L+  T PS D
Sbjct: 544 ALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRD 580


>gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo
           sapiens]
          Length = 652

 Score =  518 bits (1333), Expect = e-147
 Identities = 254/577 (44%), Positives = 373/577 (64%), Gaps = 23/577 (3%)

Query: 32  GAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIP 91
           GA P+     KRD+ + +RG+W N++EFVL+  G  +GLGNVWRFPYLCY+NGGGAF+ P
Sbjct: 31  GAVPSE--ATKRDQNL-KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFP 87

Query: 92  YVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIIL 151
           Y +  I CGIP+FF+E + GQF S+G +  WR + P+F+G+GY   V+  ++ +YY +++
Sbjct: 88  YFIMLIFCGIPLFFMELSFGQFASQGCLGVWR-ISPMFKGVGYGMMVVSTYIGIYYNVVI 146

Query: 152 AWAIFYLSNCFTTELPWATCGHEWNTENCVEFQKLN-----------VSNYSHV---SLQ 197
             A +Y  +  T  LPWA C + WNT +C      +            SN SH+   SLQ
Sbjct: 147 CIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQ 206

Query: 198 NATSPVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVT 257
             TSP  E+W   VL +SD I + G +R  L  CL  +W + + C+ +G KS+GKVVY T
Sbjct: 207 R-TSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFT 265

Query: 258 ATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCL 317
           ATFPY++L IL +RGVTL GA +GI +YL P   ++ + +VW DA +QIF+S     G L
Sbjct: 266 ATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGL 325

Query: 318 TALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGL 377
             + SYN ++NNCYRD +++   N  TS  AGF IFS+LGFMA   GV ++ VA+ GPGL
Sbjct: 326 ITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGL 385

Query: 378 AFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRE 437
           AF+AYP+A+T++P+SPLW+ LFF MLI LGL +QF  +E+LVTA+VD     +    ++ 
Sbjct: 386 AFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWIL-QKKT 444

Query: 438 LLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFY 497
            + L ++V  + LG+ + ++ G+Y   L D+YAAS   L+ ++   C+ I ++YG   ++
Sbjct: 445 YVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYF 503

Query: 498 DNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLM 557
            +I+ M+G+ PP   + CW  ++P I   I +F +I+Y+P+ YN+ Y YP W   IG+LM
Sbjct: 504 QDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLM 562

Query: 558 ALSSMLCIPLWICITVWKTEG-TLPEKLQKLTTPSTD 593
           ALSS+LCIPL+    + +T+G TL ++L+  T PS D
Sbjct: 563 ALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRD 599


>gi|92859670 solute carrier family 6 (neurotransmitter transporter,
           glycine), member 5 [Homo sapiens]
          Length = 797

 Score =  517 bits (1332), Expect = e-146
 Identities = 254/572 (44%), Positives = 365/572 (63%), Gaps = 33/572 (5%)

Query: 50  RGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETA 109
           RG+W++K++F+LS+ G  +GLGNVWRFPYL ++NGGGAFLIPY++     G+P+FFLE +
Sbjct: 191 RGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVS 250

Query: 110 LGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWA 169
           LGQF S+G ++ W+ + P  +G G A  +I   + +YY +I+ + +FYL   F + LPW 
Sbjct: 251 LGQFASQGPVSVWKAI-PALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWG 309

Query: 170 TCGHEWNTENCVEFQKLNVSN--------------------YSHVSLQNATSPVM----- 204
           +C + WNT  C +  KL + +                    Y +V++ N TS        
Sbjct: 310 SCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAYPNVTMVNFTSQANKTFVS 369

Query: 205 ---EFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFP 261
              E++++ VL IS GIE+ G +RW LALCL  AW I Y  + KG K++GKVVY TATFP
Sbjct: 370 GSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTSGKVVYFTATFP 429

Query: 262 YIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALG 321
           Y++L+ILLIRGVTLPGA  GI +++ P   +L+D  VW DA TQIFFS +   G L  L 
Sbjct: 430 YVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLS 489

Query: 322 SYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIA 381
           SYN ++NNCYRD +++ C NS TS  AGF IFSV+GFMA E+ V I  VA+ GPG+AF+ 
Sbjct: 490 SYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVV 549

Query: 382 YPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLIL 441
           YP+A+T +PLSP WA +FF+ML+ LGLD+ F  +E++VT++ D +PK  R    + +  L
Sbjct: 550 YPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRT--HKPVFTL 607

Query: 442 ALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIE 501
              +  + +G  M+T+GG+Y+FQL D+YAAS   L+ +AIFE + I +VYG  RF ++IE
Sbjct: 608 GCCICFFIMGFPMITQGGIYMFQLVDTYAAS-YALVIIAIFELVGISYVYGLQRFCEDIE 666

Query: 502 DMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSS 561
            MIG++P    K CW  +TP I   I  F   +++P+ Y + Y YP W   +GWLM   S
Sbjct: 667 MMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGS-YRYPNWSMVLGWLMLACS 725

Query: 562 MLCIPLWICITVWKTEGTLPEKLQKLTTPSTD 593
           ++ IP+   I +    G   E+L+ + +P  D
Sbjct: 726 VIWIPIMFVIKMHLAPGRFIERLKLVCSPQPD 757


>gi|4557046 solute carrier family 6 member 2 [Homo sapiens]
          Length = 617

 Score =  513 bits (1322), Expect = e-145
 Identities = 249/556 (44%), Positives = 359/556 (64%), Gaps = 12/556 (2%)

Query: 43  RDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIP 102
           RD     R  W  K++F+LSV G  + L NVWRFPYLCYKNGGGAFLIPY +F I  G+P
Sbjct: 49  RDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMP 108

Query: 103 VFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCF 162
           +F++E ALGQ+  EG  T W K+CP F+G+GYA  +I  ++  YY +I+AW+++YL + F
Sbjct: 109 LFYMELALGQYNREGAATVW-KICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSF 167

Query: 163 TTELPWATCGHEWNTENCVEFQKLNVS---NYSHVSLQNATSPVMEFWEHRVLAI--SDG 217
           T  LPW  CGH WN+ NC + + LN S   N++  S    T P  EF+E  VL +  S G
Sbjct: 168 TLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFT-PAAEFYERGVLHLHESSG 226

Query: 218 IEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPG 277
           I  IG  +W+L LCL+    + YF +WKG K++GKVV++TAT PY +L +LL+ GVTLPG
Sbjct: 227 IHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPG 286

Query: 278 ASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIML 337
           AS GI  YL+ D  RL +  VW+DA TQIFFS     G L A  SYN ++NNCYRD ++ 
Sbjct: 287 ASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLT 346

Query: 338 CCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWAT 397
             +N  TSFV+GFAIFS+LG+MA+E  V I +VA  G GL FI YP+A++ +  S  WA 
Sbjct: 347 SSINCITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAV 406

Query: 398 LFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTE 457
           +FF+ML+ LGLDS    +E+++T + D + +V +R   R+L    ++  ++ L L  +T+
Sbjct: 407 VFFVMLLALGLDSSMGGMEAVITGLADDF-QVLKR--HRKLFTFGVTFSTFLLALFCITK 463

Query: 458 GGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWM 517
           GG+Y+  L D++AA G  +LF  + E I + W YG +RF ++I+ M+G+RP    + CW 
Sbjct: 464 GGIYVLTLLDTFAA-GTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWK 522

Query: 518 IMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTE 577
            ++P     + +  +I +KPL Y++ Y +P W   +GW +ALSSM+ +P+++      T+
Sbjct: 523 FVSPAFLLFVVVVSIINFKPLTYDD-YIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQ 581

Query: 578 GTLPEKLQKLTTPSTD 593
           G+L E+L    TP  +
Sbjct: 582 GSLWERLAYGITPENE 597


>gi|134304856 solute carrier family 6, member 7 [Homo sapiens]
          Length = 636

 Score =  513 bits (1321), Expect = e-145
 Identities = 258/553 (46%), Positives = 361/553 (65%), Gaps = 9/553 (1%)

Query: 44  DKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPV 103
           D A H RG+W  K++F+LS  G  +GLGNVWRFPY  Y NGGGAFL+PY +    CGIP+
Sbjct: 32  DFAAH-RGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPL 90

Query: 104 FFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFT 163
           FFLE +LGQF+S G +  W K+ PLF+G G A  +I   + +YY +I+A+ +FYL    T
Sbjct: 91  FFLELSLGQFSSLGPLAVW-KISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLT 149

Query: 164 TELPWATCGHEWNTENCVEFQKLNVSNYS-HVSLQNATSPVMEFWEHRVLAI--SDGIEH 220
           ++LPW  CG+ WNTE C+E +     N +  ++L    SP  E+W   VL I  S GI  
Sbjct: 150 SDLPWEHCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYWSRYVLHIQGSQGIGS 209

Query: 221 IGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASE 280
            G +RW L LCLL AW I + CI KG KS+GKVVY TATFPY++LL+LL+RGVTLPGA +
Sbjct: 210 PGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWK 269

Query: 281 GIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCL 340
           GI+FYL P    L   +VW++A  QIF+S  +  G L    SYN ++ N YRD  ++   
Sbjct: 270 GIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLG 329

Query: 341 NSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFF 400
           N+ TS +AGFAIFSVLG+M+ E GVP+ +VA++GPGLAF+ YP+A+TM+PLSP W+ LFF
Sbjct: 330 NAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFF 389

Query: 401 MMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGM 460
            ML+ LGLDSQF  +E++VTAV D +P   R   ++ +    + V  Y +GL++ T+GGM
Sbjct: 390 FMLLTLGLDSQFAFLETIVTAVTDEFPYYLRP--KKAVFSGLICVAMYLMGLILTTDGGM 447

Query: 461 YIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMT 520
           Y   L D Y+AS   L+ V I  C+ +  VYG  RF  +I  M+G++P    + CW+ ++
Sbjct: 448 YWLVLLDDYSAS-FGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLS 506

Query: 521 PGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTL 580
           P     + ++ ++KY+P +Y + Y +P W   +G LM L S L IP  + + V + EG+L
Sbjct: 507 PATLLALMVYSIVKYQPSEYGS-YRFPPWAELLGILMGLLSCLMIPAGMLVAVLREEGSL 565

Query: 581 PEKLQKLTTPSTD 593
            E+LQ+ + P+ D
Sbjct: 566 WERLQQASRPAMD 578


>gi|4507043 solute carrier family 6 member 4 [Homo sapiens]
          Length = 630

 Score =  509 bits (1310), Expect = e-144
 Identities = 254/574 (44%), Positives = 367/574 (63%), Gaps = 13/574 (2%)

Query: 23  APGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYK 82
           +PG G  +  + PA    +  +    ER  W  KV+F+LSV G  + LGNVWRFPY+CY+
Sbjct: 52  SPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQ 111

Query: 83  NGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAH 142
           NGGGAFL+PY +  I  GIP+F++E ALGQ+   G I+ WRK+CP+F+GIGYA  +I  +
Sbjct: 112 NGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFY 171

Query: 143 LNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTENCVE-FQKLNVSNYSHVSLQNATS 201
           +  YY  I+AWA++YL + FT +LPW +C + WNT NC   F + N++   H     +TS
Sbjct: 172 IASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLH-----STS 226

Query: 202 PVMEFWEHRVLAI--SDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTAT 259
           P  EF+   VL I  S G++ +G + W+LALC++  +T+ YF IWKG K++GKVV+VTAT
Sbjct: 227 PAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTAT 286

Query: 260 FPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTA 319
           FPYI+L +LL+RG TLPGA  G+ FYL P+  +L +  VW+DA  QIFFS     G L A
Sbjct: 287 FPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLA 346

Query: 320 LGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVA-ESGPGLA 378
             SYN +NNNCY+D ++   +N  TSFV+GF IF+VLG+MA  +   ++EVA ++GP L 
Sbjct: 347 FASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLL 406

Query: 379 FIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRREL 438
           FI Y +A+  MP S  +A +FF+MLI LGLDS F  +E ++TAV+D +P V+ +  RRE 
Sbjct: 407 FITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAK--RRER 464

Query: 439 LILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYD 498
            +LA+ +  +F  LV LT GG Y+ +L + Y A+G  +L VA+ E + + W YG  +F  
Sbjct: 465 FVLAVVITCFFGSLVTLTFGGAYVVKLLEEY-ATGPAVLTVALIEAVAVSWFYGITQFCR 523

Query: 499 NIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMA 558
           ++++M+G+ P    + CW+ ++P     I   FL+    L+    Y YP W   +G+ + 
Sbjct: 524 DVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQ-YNYPYWSIILGYCIG 582

Query: 559 LSSMLCIPLWICITVWKTEGTLPEKLQKLTTPST 592
            SS +CIP +I   +  T GT  E++ K  TP T
Sbjct: 583 TSSFICIPTYIAYRLIITPGTFKERIIKSITPET 616


>gi|4507041 solute carrier family 6 (neurotransmitter transporter,
           dopamine), member 3 [Homo sapiens]
          Length = 620

 Score =  493 bits (1268), Expect = e-139
 Identities = 234/551 (42%), Positives = 347/551 (62%), Gaps = 9/551 (1%)

Query: 49  ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 108
           +R  W  K++F+LSV G  + L NVWRFPYLCYKNGGGAFL+PY++F +  G+P+F++E 
Sbjct: 59  DRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMEL 118

Query: 109 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPW 168
           ALGQF  EG    W K+CP+ +G+G+   +I  ++  +Y +I+AWA+ YL + FTTELPW
Sbjct: 119 ALGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPW 177

Query: 169 ATCGHEWNTENCVEFQKLNVS-NYSHVSLQNATSPVMEFWEHRVLAI--SDGIEHIGNLR 225
             C + WN+ NC +    + S + S ++    T+P  E++E  VL +  S GI+ +G  R
Sbjct: 178 IHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPR 237

Query: 226 WELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFY 285
           W+L  CL+    + YF +WKG K++GKVV++TAT PY++L  LL+RGVTLPGA +GI+ Y
Sbjct: 238 WQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAY 297

Query: 286 LYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTS 345
           L  D  RL +  VW+DA TQ+ FS  +  G L A  SYN + NNCYRD I+   +NS TS
Sbjct: 298 LSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTS 357

Query: 346 FVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIF 405
           F +GF +FS LG+MA +  VPI +VA+ GPGL FI YP+A+  +PLS  WA +FF+ML+ 
Sbjct: 358 FSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLT 417

Query: 406 LGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQL 465
           LG+DS    +ES++T ++D +  + R    REL  L + + ++ L L  +T GG+Y+F L
Sbjct: 418 LGIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYVFTL 474

Query: 466 FDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICA 525
            D +AA G  +LF  + E I + W YG  +F D+I+ M G RP    + CW +++P    
Sbjct: 475 LDHFAA-GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLL 533

Query: 526 GIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEKLQ 585
            + +  ++ ++P  Y   Y +P W   +GW++A SSM  +P++         G+  EKL 
Sbjct: 534 FVVVVSIVTFRPPHY-GAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLA 592

Query: 586 KLTTPSTDLKM 596
               P  D ++
Sbjct: 593 YAIAPEKDREL 603


>gi|6005715 solute carrier family 6 (amino acid transporter), member
           14 [Homo sapiens]
          Length = 642

 Score =  461 bits (1187), Expect = e-130
 Identities = 236/577 (40%), Positives = 348/577 (60%), Gaps = 38/577 (6%)

Query: 49  ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 108
           +RG+W+ K +++LS+ G  +GLGNVWRFPYL Y NGGGAFLIPY +     G+P+FFLE 
Sbjct: 35  DRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLEC 94

Query: 109 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPW 168
           +LGQF S G ++ WR + PLF+G+G    +I   + +YY +I+A++++Y+   F +ELPW
Sbjct: 95  SLGQFASLGPVSVWR-ILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPW 153

Query: 169 ATCGHEWNTENCVE---------------FQKLNVSNYSHVSLQNATS------------ 201
             C   W+ +NC                  Q++   N S V + N T             
Sbjct: 154 KNCS-SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQL 212

Query: 202 PVMEFWEHRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFP 261
           P  ++W    L  S G+   G + W LALCLL AW I    ++KG KS+GKVVY TA FP
Sbjct: 213 PSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFP 272

Query: 262 YIMLLILLIRGVTLPGASEGIKFYL--YPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTA 319
           Y++LLILL+RG TL GAS+GI +Y+    + ++L + +VW DA TQIF+S ++  G L A
Sbjct: 273 YVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVA 332

Query: 320 LGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAF 379
           L SYN + NNC+ D I++C  N  TS  AGFAIFS+LG MA+  G  +++V +SG  LAF
Sbjct: 333 LSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAF 392

Query: 380 IAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELL 439
           IAYP+A+  +P  P W+ LFF ML+ LGLDSQF  +E++ T + D++PKV ++   R  +
Sbjct: 393 IAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKK--MRVPI 450

Query: 440 ILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDN 499
            L   ++ + LGLV +T+ G+Y   L D + A G  +L  AI E + I W+YG NRF ++
Sbjct: 451 TLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCA-GWGILIAAILELVGIIWIYGGNRFIED 509

Query: 500 IEDMIGYRPPSLIKW---CWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWL 556
            E MIG +      W   CW ++TP +   IFI+ L+++    Y  I  YP WG  +GW 
Sbjct: 510 TEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAI-PYPDWGVALGWC 568

Query: 557 MALSSMLCIPLWICITVWKTEGTLPEKLQKLTTPSTD 593
           M +  ++ IP+   I + + +G + ++L     P+++
Sbjct: 569 MIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASN 605


>gi|51468073 solute carrier family 6, member 19 [Homo sapiens]
          Length = 634

 Score =  362 bits (930), Expect = e-100
 Identities = 201/617 (32%), Positives = 316/617 (51%), Gaps = 82/617 (13%)

Query: 50  RGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETA 109
           R  W+NK +++L+  G  +GLGNVWRFPYLC  +GGGAF+IP+++  +  GIP+ +LE A
Sbjct: 32  RPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLYLEFA 91

Query: 110 LGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWA 169
           +GQ    G +  W  + P  +G+G A+ +    + +YY  I++W ++YL N F   LPW+
Sbjct: 92  IGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQEPLPWS 151

Query: 170 TCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELA 229
            C              LN +   +V     +SPV  FW    L IS  I   G+++W + 
Sbjct: 152 DC-------------PLNENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWWML 198

Query: 230 LCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPD 289
           LCL  AW++ Y C  +G ++TGK VY+T+T PY++L I LIRG+TL GA+ GI F   P+
Sbjct: 199 LCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPN 258

Query: 290 LSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAG 349
           ++ L+ P  W+DAG Q+FFS+++  G L +  SYN+ +NNC +D +++  +N  TS    
Sbjct: 259 VTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIINGFTSVYVA 318

Query: 350 FAIFSVLGFMAYEQ----------------GVPIAEVAE--------------------- 372
             ++SV+GF A ++                 +P   V +                     
Sbjct: 319 IVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRCNASDPAAYAQL 378

Query: 373 ---------------SGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVES 417
                           G GLAFI + +A+T MPLSPLW+ LFF+ML  LGL S F  +E 
Sbjct: 379 VFQTCDINAFLSEAVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSSMFGNMEG 438

Query: 418 LVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLL 477
           +V  + D+  +V    + +E+L   + + ++ +G +     G Y   L DSYA S + LL
Sbjct: 439 VVVPLQDL--RVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGS-IPLL 495

Query: 478 FVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLI---- 533
            +A  E   + +VYG +RF  +IE MIG++P    +  W +++P +   IF+FF +    
Sbjct: 496 IIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLIIFLFFFVVEVS 555

Query: 534 ----------KYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLPEK 583
                      Y+    +   +YP W Y +  ++A    L IP +    + +     P  
Sbjct: 556 QELTYSIWDPGYEEFPKSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYKLIRNHCQKPGD 615

Query: 584 LQKLTTPSTDLKMRGKL 600
            Q L +  +   M G L
Sbjct: 616 HQGLVSTLSTASMNGDL 632


>gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo
           sapiens]
          Length = 592

 Score =  346 bits (888), Expect = 3e-95
 Identities = 199/585 (34%), Positives = 297/585 (50%), Gaps = 90/585 (15%)

Query: 53  WNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQ 112
           W N ++FV +     +GLGNVWRFPYLC   GGG+FL+PY++  I  G+P+ +LE A+GQ
Sbjct: 8   WANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQ 67

Query: 113 FTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCG 172
              +G I  WR + P   G+G A+ V+   L++YY +I AWA +YL + F   LPW+ C 
Sbjct: 68  RMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVC- 126

Query: 173 HEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCL 232
                        LN ++  +       S    FW  + L IS  ++  G ++WE ALCL
Sbjct: 127 ------------PLNGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCL 174

Query: 233 LAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSR 292
           L AW + Y CI +GT+STGKVVY TA+ PY +L+I LIRG+TL GA+ G+ +   P + +
Sbjct: 175 LLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKIEQ 234

Query: 293 LSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAI 352
           L++P+ W++A TQIFFS  +  G L A  SYN  +NNC +  I++  +NS TS  A    
Sbjct: 235 LANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVT 294

Query: 353 FSVLGFMA--------------------YEQGVPIAEVAESGPG---------------- 376
           FS+ GF A                     E G   A   E   G                
Sbjct: 295 FSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQ 354

Query: 377 ------------------LAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESL 418
                             LAFI Y +A+  M +S LW+ L+F ML+ LG+ S      ++
Sbjct: 355 IKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAI 414

Query: 419 VTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLF 478
           +T + D   K+      +E +   + +++  +G+V   E G Y F +F+ YAA+ + LL 
Sbjct: 415 LTPLTD--SKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAAT-LSLLL 471

Query: 479 VAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIM----TPGICAGIFIFFLIK 534
           + + E I + +VYG  RF  +++ M G      + W W +M    +P +   +F+F+L  
Sbjct: 472 IVLVETIAVCYVYGLRRFESDLKAMTG----RAVSWYWKVMWAGVSPLLIVSLFVFYLSD 527

Query: 535 Y---KPLKY-------NNIYT--YPAWGYGIGWLMALSSMLCIPL 567
           Y     LKY         + T  YPA+   +  L+  SS +CIPL
Sbjct: 528 YILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPL 572


>gi|194018524 solute carrier family 6, member 18 [Homo sapiens]
          Length = 628

 Score =  340 bits (873), Expect = 2e-93
 Identities = 199/585 (34%), Positives = 306/585 (52%), Gaps = 83/585 (14%)

Query: 49  ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 108
           ER  W+NK +++LS  G  +GLGN+WRFPYLC   GGGAFLIPYV+  +  GIP+F +E 
Sbjct: 17  ERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVFEGIPIFHVEL 76

Query: 109 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPW 168
           A+GQ   +G +  W  + P   G+G     +   +++YY  I+AW ++YL N F   LPW
Sbjct: 77  AIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSFQHPLPW 136

Query: 169 ATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWEL 228
           ++C  + N    VE  +              +S V  FW  + L I+  I   G+++W L
Sbjct: 137 SSCPPDLNRTGFVEECQ-------------GSSAVSYFWYRQTLNITADINDSGSIQWWL 183

Query: 229 ALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYP 288
            +CL A+W + Y C+ +G ++TGKV+Y TA FPY++L I LIRG+TLPGA++G+ +   P
Sbjct: 184 LICLAASWAVVYMCVIRGIETTGKVIYFTALFPYLVLTIFLIRGLTLPGATKGLIYLFTP 243

Query: 289 DLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVA 348
           ++  L +P+VW+DA TQIFFS ++  G   A  SYN+  N+C +D +++  +N  TS  A
Sbjct: 244 NMHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAVVIALVNRMTSLYA 303

Query: 349 GFAIFSVLGFMA---YEQ-------------GVPIAEVA-ESGPGLAF---IAYPKAVTM 388
             A+FSVLGF A   YE                P   ++ +  P +       +PK V  
Sbjct: 304 SIAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMHLNATWPKRVAQ 363

Query: 389 MPL--------------------------------SPLWATLFFMMLIFLGLDSQFVCVE 416
           +PL                                +P+WA LFF ML  LGL + F  VE
Sbjct: 364 LPLKACLLEDFLDKSASGPGLAFVVFTETDLHMPGAPVWAMLFFGMLFTLGLSTMFGTVE 423

Query: 417 SLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCL 476
           +++T ++D+   V  R   +E L   + ++ +        + G Y  ++FD++AAS   L
Sbjct: 424 AVITPLLDV--GVLPRWVPKEALTGLVCLVCFLSATCFTLQSGNYWLEIFDNFAASPN-L 480

Query: 477 LFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIK-- 534
           L +A  E + + +VYG  RF D+I  M G RP    +  W +++P +   IF+ ++I   
Sbjct: 481 LMLAFLEVVGVVYVYGMKRFCDDIAWMTGRRPSPYWRLTWRVVSP-LLLTIFVAYIILLF 539

Query: 535 YKPLKY---NNIY---------TYPAWGYGIGWLMALSSMLCIPL 567
           +KPL+Y   N  Y          YP W      L++L  +L +P+
Sbjct: 540 WKPLRYKAWNPKYELFPSRQEKLYPGWARAACVLLSLLPVLWVPV 584


>gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo
           sapiens]
          Length = 555

 Score =  290 bits (743), Expect = 2e-78
 Identities = 180/585 (30%), Positives = 271/585 (46%), Gaps = 127/585 (21%)

Query: 53  WNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQ 112
           W N ++FV +     +GLGNVWRFPYLC   GGG+FL+PY++  I  G+P+ +LE A+GQ
Sbjct: 8   WANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQ 67

Query: 113 FTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCG 172
              +G I  WR + P   G+G A+ V+   L++YY +I AWA +YL + F   LPW+ C 
Sbjct: 68  RMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVC- 126

Query: 173 HEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNLRWELALCL 232
                        LN ++  +       S    FW  + L IS  ++  G ++WE ALCL
Sbjct: 127 ------------PLNGNHTGYDEECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCL 174

Query: 233 LAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSR 292
           L AW + Y CI +GT+STGK+                                      +
Sbjct: 175 LLAWLVVYLCILRGTESTGKI-------------------------------------EQ 197

Query: 293 LSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAI 352
           L++P+ W++A TQIFFS  +  G L A  SYN  +NNC +  I++  +NS TS  A    
Sbjct: 198 LANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVT 257

Query: 353 FSVLGFMA--------------------YEQGVPIAEVAESGPG---------------- 376
           FS+ GF A                     E G   A   E   G                
Sbjct: 258 FSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQ 317

Query: 377 ------------------LAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESL 418
                             LAFI Y +A+  M +S LW+ L+F ML+ LG+ S      ++
Sbjct: 318 IKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAI 377

Query: 419 VTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLF 478
           +T + D   K+      +E +   + +++  +G+V   E G Y F +F+ YAA+ + LL 
Sbjct: 378 LTPLTD--SKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAAT-LSLLL 434

Query: 479 VAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIM----TPGICAGIFIFFLIK 534
           + + E I + +VYG  RF  +++ M G      + W W +M    +P +   +F+F+L  
Sbjct: 435 IVLVETIAVCYVYGLRRFESDLKAMTG----RAVSWYWKVMWAGVSPLLIVSLFVFYLSD 490

Query: 535 Y---KPLKY-------NNIYT--YPAWGYGIGWLMALSSMLCIPL 567
           Y     LKY         + T  YPA+   +  L+  SS +CIPL
Sbjct: 491 YILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPL 535


>gi|58219014 solute carrier family 6, member 17 [Homo sapiens]
          Length = 727

 Score =  274 bits (701), Expect = 2e-73
 Identities = 133/332 (40%), Positives = 194/332 (58%), Gaps = 17/332 (5%)

Query: 32  GAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIP 91
           G A  +   V+ +    +R  WN+K++++L+  G  +GLGN+WRFPYLC KNGGGA+L+P
Sbjct: 42  GEAGGKQKAVEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVP 101

Query: 92  YVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIIL 151
           Y+V  I  GIP+FFLE A+GQ    G I  W  +CP   GIG+++ ++   + +YY +I+
Sbjct: 102 YLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVII 161

Query: 152 AWAIFYLSNCFTTELPWATCGHEWNTENCV---EFQKLNVSNYSHVSLQNATSPVMEFWE 208
            W+IFY    F   LPW+ C    N    V   E +K + + Y              FW 
Sbjct: 162 GWSIFYFFKSFQYPLPWSECPVVRNGSVAVVEAECEKSSATTY--------------FWY 207

Query: 209 HRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLIL 268
              L ISD I   G L W++ LCLL AW+I    + KG +S+GKV+Y ++ FPY++L   
Sbjct: 208 REALDISDSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACF 267

Query: 269 LIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNN 328
           L+RG+ L GA +GI     P L ++ DPQVW +A TQ+FF+  +  G + A  SYN  +N
Sbjct: 268 LVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDN 327

Query: 329 NCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMA 360
           NC+ D  ++  +N  TS +A   +F+VLGF A
Sbjct: 328 NCHFDAALVSFINFFTSVLATLVVFAVLGFKA 359



 Score =  104 bits (259), Expect = 3e-22
 Identities = 49/154 (31%), Positives = 86/154 (55%), Gaps = 8/154 (5%)

Query: 374 GPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRG 433
           G GLAFIA+ +A+T  P SP W+ +FF+MLI LGL S    +  + T ++D +       
Sbjct: 437 GTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFK------ 490

Query: 434 YRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGS 493
             +E+  +   V ++ +GL+ +   G Y   +FD Y+A+ + L  + I E I + W+YG+
Sbjct: 491 VPKEMFTVGCCVFAFLVGLLFVQRSGNYFVTMFDDYSAT-LPLTLIVILENIAVAWIYGT 549

Query: 494 NRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGI 527
            +F   + +M+G+RP     + W  ++P +C  +
Sbjct: 550 KKFMQELTEMLGFRPYRFYFYMWKFVSP-LCMAV 582


>gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo
           sapiens]
          Length = 730

 Score =  259 bits (661), Expect = 7e-69
 Identities = 123/315 (39%), Positives = 186/315 (59%), Gaps = 17/315 (5%)

Query: 49  ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 108
           ER  WN+K++++L+  G  +GLGNVWRFPYLC KNGGGA+L+PY++  +  GIP+FFLE 
Sbjct: 60  ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119

Query: 109 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPW 168
           ++GQ    G I  W  + P   GIG+A+ V+   + +YY +I+ W++FY S  F   LPW
Sbjct: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179

Query: 169 ATCGHEWNTENCVEFQKLNVSNYSHVSLQ---NATSPVMEFWEHRVLAISDGIEHIGNLR 225
             C                V N SH  ++     +S    +W    L IS  I   G L 
Sbjct: 180 DQCP--------------LVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLN 225

Query: 226 WELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFY 285
           W++ +CLLAAW +    + KG +S+GK++Y ++ FPY++L+  LIR   L G+ +GI+  
Sbjct: 226 WKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSIDGIRHM 285

Query: 286 LYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTS 345
             P L  + +P+VW +A TQ+FF+  +  G + A  SYN  +NNC+ D +++  +N  TS
Sbjct: 286 FTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTS 345

Query: 346 FVAGFAIFSVLGFMA 360
            +A   +F+VLGF A
Sbjct: 346 VLATLVVFAVLGFKA 360



 Score =  121 bits (303), Expect = 2e-27
 Identities = 65/208 (31%), Positives = 115/208 (55%), Gaps = 18/208 (8%)

Query: 371 AESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVF 430
           A  G GLAFIA+ +A+T  P SP W+ +FF+ML+ LGL S F  +E +VT +VD +    
Sbjct: 435 AVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTFK--- 491

Query: 431 RRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWV 490
               R+E+L +   ++++ +GL+ +   G Y   +FD Y+A+ + LL V I E I + +V
Sbjct: 492 ---VRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSAT-LPLLIVVILENIAVCFV 547

Query: 491 YGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIK--YKPLKYN------- 541
           YG ++F ++++DM+G+ P     + W  ++P +   + I  ++     P  YN       
Sbjct: 548 YGIDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKA 607

Query: 542 --NIYTYPAWGYGIGWLMALSSMLCIPL 567
                +YP WG  +   + + ++L +P+
Sbjct: 608 SEEFLSYPTWGLVVCVSLVVFAILPVPV 635


>gi|197276625 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform b [Homo sapiens]
          Length = 200

 Score =  234 bits (597), Expect = 2e-61
 Identities = 107/180 (59%), Positives = 131/180 (72%), Gaps = 1/180 (0%)

Query: 30  SGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFL 89
           S G +P   P  + +    +R  W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAFL
Sbjct: 21  SPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFL 80

Query: 90  IPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYII 149
           IPY +F    G+PVFFLE  +GQ+TSEGGITCW K+CPLF GIGYA+ VI + LNVYYI+
Sbjct: 81  IPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIV 140

Query: 150 ILAWAIFYLSNCFTTELPWATCGHEWNTENCVE-FQKLNVSNYSHVSLQNATSPVMEFWE 208
           ILAWA +YL   F  ELPWA C H WNT +C+E   + N S +  +S  N TSPV+EFWE
Sbjct: 141 ILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200


>gi|55749589 solute carrier family 6, member 16 [Homo sapiens]
          Length = 736

 Score =  199 bits (507), Expect = 5e-51
 Identities = 147/599 (24%), Positives = 255/599 (42%), Gaps = 92/599 (15%)

Query: 42  KRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGI 101
           K  + +  R  W++K E++L+  G  +    +WRF YL   +GG +F   Y+      G+
Sbjct: 95  KESEVLLARPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGV 154

Query: 102 PVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNC 161
           P+ FLE A GQ   +GG+  W+ + P   G+GY++ ++   L +Y+ ++ +W IFY+S  
Sbjct: 155 PLLFLEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQS 214

Query: 162 FTTELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHI 221
           F   +PW  C              L +++         T+P + FW  + L  SD IE  
Sbjct: 215 FQFPVPWEKC-------------PLTMNSSGFDPECERTTPSIYFWYQQALKASDRIEDG 261

Query: 222 GNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEG 281
           G+  + L L     W +    +  G KSTGKV+YV    P  +++   IR + L GA  G
Sbjct: 262 GSPVYSLVLPFFLCWCLVGAFMINGLKSTGKVIYVLVLLPCFIIVGFFIRTLLLEGAKFG 321

Query: 282 IKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLN 341
           ++  +   +S + +  VW  AG Q+  +  I LG + +L SY   +NNC  D  ++  +N
Sbjct: 322 LQQLVVAKISDVYNMSVWSLAGGQVLSNTGIGLGSVASLASYMPQSNNCLSDAFLVSVIN 381

Query: 342 SGTSFVAGFAIFSVLGFM------------------------------------------ 359
             T  V     F VLGF                                           
Sbjct: 382 LLTLLVFTSFNFCVLGFWATVITHRCCERNAEILLKLINLGKLPPDAKPPVNLLYNPTSI 441

Query: 360 --AYEQGVP-------IAEVAESGPGLAFI--------AYPKAVTMMPLSPLWATLFFMM 402
             A+  G+P       + EV E      F+        A+   V  M   P      F+ 
Sbjct: 442 YNAWLSGLPQHIKSMVLREVTECNIETQFLKASEGPKFAFLSFVEAMSFLPPSVFWSFIF 501

Query: 403 LIFL---GLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGG 459
            + L   GL S    ++ ++T + D +   FR+    +LLI+ + ++ +  GL      G
Sbjct: 502 FLMLLAMGLSSAIGIMQGIITPLQDTF-SFFRK--HTKLLIVGVFLLMFVCGLFFTRPSG 558

Query: 460 MYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIM 519
            Y  +L   Y      ++ V +FE + + W YG+ RF  ++  ++G+    +  W W  +
Sbjct: 559 SYFIRLLSDYWIV-FPIIVVVVFETMAVSWAYGARRFLADLTILLGHPISPIFGWLWPHL 617

Query: 520 TPGICAGIFIFFLIK--YKPLKYNN---------IYTYPAWGYGIGWLMALSSMLCIPL 567
            P +   IF+  ++    KP+ Y +         +  YP W   +  ++ L +++ +P+
Sbjct: 618 CPVVLLIIFVTMMVHLCMKPITYMSWDSSTSKEVLRPYPPWALLL--MITLFAIVILPI 674


>gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo
           sapiens]
          Length = 623

 Score =  190 bits (483), Expect = 3e-48
 Identities = 95/264 (35%), Positives = 146/264 (55%), Gaps = 17/264 (6%)

Query: 100 GIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLS 159
           GIP+FFLE ++GQ    G I  W  + P   GIG+A+ V+   + +YY +I+ W++FY S
Sbjct: 4   GIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFS 63

Query: 160 NCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQ---NATSPVMEFWEHRVLAISD 216
             F   LPW  C                V N SH  ++     +S    +W    L IS 
Sbjct: 64  QSFQQPLPWDQCPL--------------VKNASHTFVEPECEQSSATTYYWYREALNISS 109

Query: 217 GIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLP 276
            I   G L W++ +CLLAAW +    + KG +S+GK++Y ++ FPY++L+  LIR   L 
Sbjct: 110 SISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLN 169

Query: 277 GASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIM 336
           G+ +GI+    P L  + +P+VW +A TQ+FF+  +  G + A  SYN  +NNC+ D ++
Sbjct: 170 GSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVL 229

Query: 337 LCCLNSGTSFVAGFAIFSVLGFMA 360
           +  +N  TS +A   +F+VLGF A
Sbjct: 230 VSFINFFTSVLATLVVFAVLGFKA 253



 Score =  121 bits (303), Expect = 2e-27
 Identities = 65/208 (31%), Positives = 115/208 (55%), Gaps = 18/208 (8%)

Query: 371 AESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVF 430
           A  G GLAFIA+ +A+T  P SP W+ +FF+ML+ LGL S F  +E +VT +VD +    
Sbjct: 328 AVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTFK--- 384

Query: 431 RRGYRRELLILALSVISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWV 490
               R+E+L +   ++++ +GL+ +   G Y   +FD Y+A+ + LL V I E I + +V
Sbjct: 385 ---VRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSAT-LPLLIVVILENIAVCFV 440

Query: 491 YGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGICAGIFIFFLIK--YKPLKYN------- 541
           YG ++F ++++DM+G+ P     + W  ++P +   + I  ++     P  YN       
Sbjct: 441 YGIDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKA 500

Query: 542 --NIYTYPAWGYGIGWLMALSSMLCIPL 567
                +YP WG  +   + + ++L +P+
Sbjct: 501 SEEFLSYPTWGLVVCVSLVVFAILPVPV 528


>gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo
           sapiens]
          Length = 289

 Score =  176 bits (446), Expect = 6e-44
 Identities = 87/224 (38%), Positives = 128/224 (57%), Gaps = 20/224 (8%)

Query: 49  ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLET 108
           ER  WN+K++++L+  G  +GLGNVWRFPYLC KNGGGA+L+PY++  +  GIP+FFLE 
Sbjct: 60  ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLEL 119

Query: 109 ALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPW 168
           ++GQ    G I  W  + P   GIG+A+ V+   + +YY +I+ W++FY S  F   LPW
Sbjct: 120 SVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW 179

Query: 169 ATCGHEWNTENCVEFQKLNVSNYSHVSLQ---NATSPVMEFWEHRVLAISDGIEHIGNLR 225
             C                V N SH  ++     +S    +W    L IS  I   G L 
Sbjct: 180 DQCP--------------LVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLN 225

Query: 226 WELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILL 269
           W++ +CLLAAW +    + KG +S+GKV  +    P+++LLI +
Sbjct: 226 WKMTICLLAAWVMVCLAMIKGIQSSGKVSMLE---PFLILLITI 266


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.142    0.471 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,754,771
Number of Sequences: 37866
Number of extensions: 1104230
Number of successful extensions: 3731
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3570
Number of HSP's gapped (non-prelim): 69
length of query: 632
length of database: 18,247,518
effective HSP length: 108
effective length of query: 524
effective length of database: 14,157,990
effective search space: 7418786760
effective search space used: 7418786760
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.