Guide to the Human Genome
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Name: RAPGEF4 Sequence: fasta or formatted (867aa) NCBI GI: 155030206
Description:

Rap guanine nucleotide exchange factor (GEF) 4 isoform b

Referenced in:

Ras

Other entries for this name:
alt prot [1011aa] Rap guanine nucleotide exchange factor (GEF) 4 isoform a
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1         53           2
 C cysteine            1.6         14           2
 D aspartate           5.5         48           2
 E glutamate           7.4         64           3
 F phenylalanine       4.2         36           2
 G glycine             4.4         38           2
 H histidine           3.3         29           2
 I isoleucine          4.8         42           2
 K lysine              6.6         57           2
 L leucine            10.6         92           3
 M methionine          3.5         30           2
 N asparagine          4.6         40           2
 P proline             4.7         41           2
 Q glutamine           4.8         42           2
 R arginine            5.9         51           2
 S serine              4.8         42           2
 T threonine           5.7         49           2
 V valine              7.5         65           2
 W tryptophan          0.8          7           1
 Y tyrosine            3.1         27           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rap guanine nucleotide exchange factor (GEF) 4 isof... 
RAPGEF4               0.997   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEF3               0.458   Rap guanine nucleotide exchange factor 3 isoform b ...
RAPGEF3               0.458   Rap guanine nucleotide exchange factor 3 isoform b [...
RAPGEF3               0.458   Rap guanine nucleotide exchange factor 3 isoform a ...
RAPGEF5               0.314   Rap guanine nucleotide exchange factor (GEF) 5 [Hom...
RAPGEFL1              0.209   Rap guanine nucleotide exchange factor (GEF)-like 1 [...
RAPGEF2               0.082   Rap guanine nucleotide exchange factor 2 
RAPGEF6               0.082   PDZ domain-containing guanine nucleotide exchange fa...
RAPGEF1               0.057   guanine nucleotide-releasing factor 2 isoform b [Hom...
RAPGEF1               0.057   guanine nucleotide-releasing factor 2 isoform a [Hom...
LOC100133567          0.048   PREDICTED: similar to Rap guanine nucleotide exchan...
RASGRF2               0.048   Ras protein-specific guanine nucleotide-releasing fa...
RASGRF1               0.044   Ras protein-specific guanine nucleotide-releasing f...
RASGRF1               0.044   Ras protein-specific guanine nucleotide-releasing fa...
RASGRF1               0.044   Ras protein-specific guanine nucleotide-releasing fa...
SOS1                  0.043   son of sevenless homolog 1 
RASGEF1C              0.038   RasGEF domain family, member 1C 
SOS2                  0.038   son of sevenless homolog 2 
RALGPS2               0.038   Ral GEF with PH domain and SH3 binding motif 2 [Homo...
RASGEF1B              0.037   RasGEF domain family, member 1B 
RALGPS1               0.036   Ral GEF with PH domain and SH3 binding motif 1 
RASGEF1A              0.027   RasGEF domain family, member 1A 
RASGRP3               0.026   RAS guanyl releasing protein 3 (calcium and DAG-reg...
RASGRP3               0.026   RAS guanyl releasing protein 3 (calcium and DAG-regu...
RASGRP3               0.026   RAS guanyl releasing protein 3 (calcium and DAG-regul...
DEPDC6                0.024   DEP domain containing 6 
RASGRP1               0.023   RAS guanyl releasing protein 1 isoform b 
RASGRP1               0.023   RAS guanyl releasing protein 1 isoform a 
PREX1                 0.023   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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