Guide to the Human Genome
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Name: RAPGEF3 Sequence: fasta or formatted (881aa) NCBI GI: 148747862
Description:

Rap guanine nucleotide exchange factor 3 isoform b

Referenced in:

Ras

Other entries for this name:
alt prot [923aa] Rap guanine nucleotide exchange factor 3 isoform a
alt mRNA [881aa] Rap guanine nucleotide exchange factor 3 isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.2         63           2
 C cysteine            2.0         18           2
 D aspartate           4.7         41           2
 E glutamate           6.7         59           3
 F phenylalanine       3.0         26           2
 G glycine             5.4         48           2
 H histidine           4.7         41           2
 I isoleucine          3.1         27           2
 K lysine              3.5         31           1
 L leucine            13.8        122           3
 M methionine          2.0         18           2
 N asparagine          3.3         29           1
 P proline             5.9         52           2
 Q glutamine           4.9         43           2
 R arginine            7.9         70           3
 S serine              7.2         63           2
 T threonine           4.4         39           2
 V valine              7.3         64           2
 W tryptophan          1.5         13           1
 Y tyrosine            1.6         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rap guanine nucleotide exchange factor 3 isoform b ... 
RAPGEF3               1.000   Rap guanine nucleotide exchange factor 3 isoform b [...
RAPGEF3               1.000   Rap guanine nucleotide exchange factor 3 isoform a ...
RAPGEF4               0.449   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEF4               0.449   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEF5               0.201   Rap guanine nucleotide exchange factor (GEF) 5 [Hom...
RAPGEFL1              0.135   Rap guanine nucleotide exchange factor (GEF)-like 1 [...
RAPGEF2               0.074   Rap guanine nucleotide exchange factor 2 
RAPGEF6               0.069   PDZ domain-containing guanine nucleotide exchange fa...
LOC100133567          0.057   PREDICTED: similar to Rap guanine nucleotide exchan...
RAPGEF1               0.047   guanine nucleotide-releasing factor 2 isoform b [Hom...
RAPGEF1               0.047   guanine nucleotide-releasing factor 2 isoform a [Hom...
RASGEF1B              0.035   RasGEF domain family, member 1B 
RASGEF1C              0.035   RasGEF domain family, member 1C 
RALGPS2               0.034   Ral GEF with PH domain and SH3 binding motif 2 [Homo...
RASGRP3               0.033   RAS guanyl releasing protein 3 (calcium and DAG-reg...
RASGRP3               0.033   RAS guanyl releasing protein 3 (calcium and DAG-regu...
RASGRF2               0.033   Ras protein-specific guanine nucleotide-releasing fa...
RASGRP3               0.032   RAS guanyl releasing protein 3 (calcium and DAG-regul...
RASGRF1               0.031   Ras protein-specific guanine nucleotide-releasing f...
RASGRF1               0.031   Ras protein-specific guanine nucleotide-releasing fa...
RASGRF1               0.031   Ras protein-specific guanine nucleotide-releasing fa...
RASGRP1               0.031   RAS guanyl releasing protein 1 isoform b 
RASGRP1               0.031   RAS guanyl releasing protein 1 isoform a 
RALGPS1               0.030   Ral GEF with PH domain and SH3 binding motif 1 
SOS1                  0.027   son of sevenless homolog 1 
RASGEF1A              0.026   RasGEF domain family, member 1A 
SOS2                  0.026   son of sevenless homolog 2 
RASGRP2               0.024   RAS guanyl releasing protein 2 
RASGRP2               0.024   RAS guanyl releasing protein 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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