Guide to the Human Genome
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Name: RAPGEF6 Sequence: fasta or formatted (1601aa) NCBI GI: 54633319
Description:

PDZ domain-containing guanine nucleotide exchange factor I

Referenced in:

PDZ Domain
Ras

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.9         78           2
 C cysteine            1.7         27           1
 D aspartate           6.1         98           3
 E glutamate           7.6        121           3
 F phenylalanine       3.1         49           1
 G glycine             5.1         81           2
 H histidine           3.2         51           1
 I isoleucine          5.5         88           3
 K lysine              6.6        105           2
 L leucine             9.0        144           2
 M methionine          2.6         42           2
 N asparagine          4.1         65           2
 P proline             5.4         86           3
 Q glutamine           4.6         73           2
 R arginine            5.3         85           3
 S serine             10.9        175           4
 T threonine           5.5         88           2
 V valine              6.2         99           2
 W tryptophan          0.8         13           1
 Y tyrosine            2.1         33           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   PDZ domain-containing guanine nucleotide exchange fa... 
RAPGEF2               0.550   Rap guanine nucleotide exchange factor 2 
LOC100133567          0.364   PREDICTED: similar to Rap guanine nucleotide exchan...
LOC100292648          0.046   PREDICTED: similar to hCG2036828 
RAPGEF4               0.044   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEF4               0.044   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEF5               0.043   Rap guanine nucleotide exchange factor (GEF) 5 [Hom...
RAPGEF3               0.038   Rap guanine nucleotide exchange factor 3 isoform b ...
RAPGEF3               0.038   Rap guanine nucleotide exchange factor 3 isoform b [...
RAPGEF3               0.038   Rap guanine nucleotide exchange factor 3 isoform a ...
RAPGEFL1              0.038   Rap guanine nucleotide exchange factor (GEF)-like 1 [...
RAPGEF1               0.023   guanine nucleotide-releasing factor 2 isoform b [Hom...
RAPGEF1               0.023   guanine nucleotide-releasing factor 2 isoform a [Hom...
RASGEF1C              0.022   RasGEF domain family, member 1C 
RASGEF1A              0.022   RasGEF domain family, member 1A 
RASGRF2               0.021   Ras protein-specific guanine nucleotide-releasing fa...
RASGEF1B              0.021   RasGEF domain family, member 1B 
RASGRF1               0.020   Ras protein-specific guanine nucleotide-releasing f...
RASGRF1               0.020   Ras protein-specific guanine nucleotide-releasing fa...
RASGRF1               0.020   Ras protein-specific guanine nucleotide-releasing fa...
SOS1                  0.019   son of sevenless homolog 1 
SOS2                  0.017   son of sevenless homolog 2 
RALGPS2               0.017   Ral GEF with PH domain and SH3 binding motif 2 [Homo...
DFNB31                0.017   CASK-interacting protein CIP98 isoform 1 
RASGRP1               0.016   RAS guanyl releasing protein 1 isoform b 
RASGRP1               0.016   RAS guanyl releasing protein 1 isoform a 
RGL1                  0.016   ral guanine nucleotide dissociation stimulator-like ...
RALGPS1               0.016   Ral GEF with PH domain and SH3 binding motif 1 
RALGDS                0.016   ral guanine nucleotide dissociation stimulator isofo...
RALGDS                0.016   ral guanine nucleotide dissociation stimulator isof...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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