Guide to the Human Genome
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Name: RAPGEF5 Sequence: fasta or formatted (730aa) NCBI GI: 119392077
Description:

Rap guanine nucleotide exchange factor (GEF) 5

Referenced in:

Ras

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5         40           2
 C cysteine            1.6         12           2
 D aspartate           5.3         39           2
 E glutamate           9.9         72           3
 F phenylalanine       4.1         30           2
 G glycine             3.2         23           2
 H histidine           3.7         27           1
 I isoleucine          4.9         36           1
 K lysine              7.8         57           2
 L leucine            12.1         88           3
 M methionine          1.9         14           1
 N asparagine          3.6         26           2
 P proline             2.7         20           2
 Q glutamine           6.2         45           2
 R arginine            4.2         31           2
 S serine              6.8         50           2
 T threonine           4.7         34           2
 V valine              7.1         52           3
 W tryptophan          1.4         10           1
 Y tyrosine            3.3         24           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rap guanine nucleotide exchange factor (GEF) 5 [Hom... 
RAPGEF4               0.376   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEF4               0.376   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEF3               0.247   Rap guanine nucleotide exchange factor 3 isoform b ...
RAPGEF3               0.247   Rap guanine nucleotide exchange factor 3 isoform b [...
RAPGEF3               0.247   Rap guanine nucleotide exchange factor 3 isoform a ...
RAPGEFL1              0.226   Rap guanine nucleotide exchange factor (GEF)-like 1 [...
RAPGEF2               0.100   Rap guanine nucleotide exchange factor 2 
RAPGEF6               0.094   PDZ domain-containing guanine nucleotide exchange fa...
RASGRF2               0.061   Ras protein-specific guanine nucleotide-releasing fa...
RAPGEF1               0.061   guanine nucleotide-releasing factor 2 isoform b [Hom...
RAPGEF1               0.061   guanine nucleotide-releasing factor 2 isoform a [Hom...
RASGRF1               0.059   Ras protein-specific guanine nucleotide-releasing f...
RASGRF1               0.059   Ras protein-specific guanine nucleotide-releasing fa...
RASGRF1               0.059   Ras protein-specific guanine nucleotide-releasing fa...
RALGPS2               0.045   Ral GEF with PH domain and SH3 binding motif 2 [Homo...
RALGPS1               0.043   Ral GEF with PH domain and SH3 binding motif 1 
RASGEF1B              0.043   RasGEF domain family, member 1B 
SOS1                  0.043   son of sevenless homolog 1 
RASGEF1C              0.039   RasGEF domain family, member 1C 
SOS2                  0.037   son of sevenless homolog 2 
RASGRP1               0.036   RAS guanyl releasing protein 1 isoform b 
RASGRP1               0.036   RAS guanyl releasing protein 1 isoform a 
RASGRP3               0.033   RAS guanyl releasing protein 3 (calcium and DAG-reg...
RASGRP3               0.033   RAS guanyl releasing protein 3 (calcium and DAG-regu...
RASGRP3               0.033   RAS guanyl releasing protein 3 (calcium and DAG-regul...
RASGEF1A              0.031   RasGEF domain family, member 1A 
RASGRP4               0.024   RAS guanyl releasing protein 4 isoform a 
RASGRP4               0.024   RAS guanyl releasing protein 4 isoform b 
LOC100133567          0.024   PREDICTED: similar to Rap guanine nucleotide exchan...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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