Guide to the Human Genome
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Search of human proteins with 7657234

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657234 small acidic protein isoform a [Homo sapiens]
         (183 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657234 small acidic protein isoform a [Homo sapiens]              376   e-105
gi|218505711 small acidic protein isoform b [Homo sapiens]            288   2e-78
gi|4504487 histidine rich calcium binding protein precursor [Hom...    49   3e-06
gi|16445033 ACRC protein [Homo sapiens]                                47   1e-05
gi|115529449 upstream binding transcription factor, RNA polymera...    45   3e-05
gi|115529451 upstream binding transcription factor, RNA polymera...    45   3e-05
gi|7657671 upstream binding transcription factor, RNA polymerase...    45   3e-05
gi|55956788 nucleolin [Homo sapiens]                                   45   3e-05
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      45   5e-05
gi|42740903 MTERF domain containing 2 [Homo sapiens]                   44   8e-05
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          44   8e-05
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    44   8e-05
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]                   44   1e-04
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]                   44   1e-04
gi|111607441 hypothetical protein LOC400506 [Homo sapiens]             44   1e-04
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa...    44   1e-04
gi|55769587 probable nucleolar complex protein 14 [Homo sapiens]       43   1e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    43   2e-04
gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]                   42   2e-04
gi|21361639 DIPB protein [Homo sapiens]                                42   3e-04
gi|17975763 myelin transcription factor 1 [Homo sapiens]               42   3e-04
gi|10835067 autoantigen La [Homo sapiens]                              42   4e-04
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    42   4e-04
gi|215422388 death-domain associated protein isoform a [Homo sap...    42   4e-04
gi|215422366 death-domain associated protein isoform b [Homo sap...    42   4e-04
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo...    42   4e-04
gi|4557509 cylicin 2 [Homo sapiens]                                    41   5e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    41   5e-04
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]    41   5e-04
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]     41   5e-04

>gi|7657234 small acidic protein isoform a [Homo sapiens]
          Length = 183

 Score =  376 bits (966), Expect = e-105
 Identities = 183/183 (100%), Positives = 183/183 (100%)

Query: 1   MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGD 60
           MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGD
Sbjct: 1   MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGD 60

Query: 61  HKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDD 120
           HKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDD
Sbjct: 61  HKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDD 120

Query: 121 DDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKS 180
           DDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKS
Sbjct: 121 DDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKS 180

Query: 181 SGS 183
           SGS
Sbjct: 181 SGS 183


>gi|218505711 small acidic protein isoform b [Homo sapiens]
          Length = 139

 Score =  288 bits (736), Expect = 2e-78
 Identities = 139/139 (100%), Positives = 139/139 (100%)

Query: 45  MGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGF 104
           MGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGF
Sbjct: 1   MGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGF 60

Query: 105 SEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPK 164
           SEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPK
Sbjct: 61  SEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPK 120

Query: 165 NKKDAKSNYKMMFVKSSGS 183
           NKKDAKSNYKMMFVKSSGS
Sbjct: 121 NKKDAKSNYKMMFVKSSGS 139


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 7/112 (6%)

Query: 70  GEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVED-------HDGEGDVAGDDDD 122
           GE+D+   EE E + ++   ++   +  RH G G  E ED       H       G ++D
Sbjct: 187 GEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEED 246

Query: 123 DDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYK 174
           DDDD  D +  DD +   E   +    +    E  ++V D  + +D    ++
Sbjct: 247 DDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHR 298



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 25/109 (22%), Positives = 51/109 (46%), Gaps = 7/109 (6%)

Query: 62  KSTSHFRT--GEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGD 119
           K  SH R    EE+K+  E+    +++  +S   G    H G    E E+ + EG     
Sbjct: 472 KDRSHLRKDDSEEEKEKEED-PGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSL 530

Query: 120 DDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKD 168
           + +++++    E  ++ E + + E+ E   E+ A   PD  E+ + +++
Sbjct: 531 NQEEEEE----EDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEE 575



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 44/177 (24%), Positives = 68/177 (38%), Gaps = 18/177 (10%)

Query: 6   ESHPHGVK---RSASPDDDLGSSNWEAADLGNE---ERKQKFLRLMGAGKKEHTGRLVIG 59
           E H H ++   R    +DD G    E  +   E   E   +  R  G G +E        
Sbjct: 172 EHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGH 231

Query: 60  DHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYR--RHCGLGFSEVED-HDG---- 112
            H   SH   G E+   +++ +       D  +  R++  RH G G  E ED  DG    
Sbjct: 232 HHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHR 291

Query: 113 ---EGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNK 166
                  + ++DD+DDD    E    +    +  KEE   E  + EH   V D +++
Sbjct: 292 DPSHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEE--VEAVSGEHHHHVPDHRHQ 346



 Score = 34.7 bits (78), Expect = 0.047
 Identities = 39/179 (21%), Positives = 66/179 (36%), Gaps = 19/179 (10%)

Query: 7   SHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSH 66
           SH H        DDD    + +  D+  E R Q   R  G G +E         H+  SH
Sbjct: 237 SHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAH-RHQGHGIEEDEDVSDGHHHRDPSH 295

Query: 67  -FRTGEEDKKINEELESQY----------QQSMDSKLSGRYRRHCGLGFSEVEDHDGEGD 115
             R+ EED   ++++ ++Y          ++     +SG +  H       V DH  +G 
Sbjct: 296 RHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHH-------VPDHRHQGH 348

Query: 116 VAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYK 174
              ++D+D       + P         E+EE  E      H      P+  K  + +++
Sbjct: 349 RDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQ 407



 Score = 32.0 bits (71), Expect = 0.30
 Identities = 40/207 (19%), Positives = 70/207 (33%), Gaps = 50/207 (24%)

Query: 8   HPHGVKRSASPDDDLGSSNWEAAD-------LGNEERKQKFLRLMGAGKKEHTGRLVIGD 60
           H H   R    D+D+ +  W           +  EE +++     G     H  R     
Sbjct: 343 HRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPR----G 398

Query: 61  HKSTS----------------HFRTGEEDKKINEELESQ---YQQSMDSKLSGRYRR--- 98
           HKS                  H    EED++++ EL  Q   ++QS   + +G  +R   
Sbjct: 399 HKSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSI 458

Query: 99  -----------------HCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSE 141
                            H     SE E    E   + ++DD+  +  +  +   S    +
Sbjct: 459 KEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQED 518

Query: 142 SEKEESAEELQAAEHPDEVEDPKNKKD 168
            E EE    L   +  +E ED + +++
Sbjct: 519 EEDEEEGHGLSLNQEEEEEEDKEEEEE 545


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 5/69 (7%)

Query: 105 SEVEDHDGEGDVAGDDDDDDDDSPDP-----ESPDDSESDSESEKEESAEELQAAEHPDE 159
           SE  D   +   A DD  DD ++PD      E+PDDS  DSE+  + S +   + +  D+
Sbjct: 242 SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDD 301

Query: 160 VEDPKNKKD 168
            E P +K D
Sbjct: 302 SEAPDDKSD 310



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 22/61 (36%), Positives = 31/61 (50%)

Query: 108 EDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKK 167
           +D D   D + D D  DD S D E+PDDS  DSE+  + S +     +  D+ E P +  
Sbjct: 220 DDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS 279

Query: 168 D 168
           D
Sbjct: 280 D 280



 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 8/69 (11%)

Query: 108 EDHDGEGDVAGDDDDD----DDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDP 163
           +D   + DV  D  DD    DD S D E+PDDS  DSE+  + S +    +E PD+  D 
Sbjct: 226 DDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDD----SEAPDDSSDD 281

Query: 164 KNKKDAKSN 172
               D  S+
Sbjct: 282 SEASDDSSD 290



 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 20/53 (37%), Positives = 30/53 (56%)

Query: 116 VAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKD 168
           V  DDD+DDD+  D E PDD+  DSE+  + S +     ++ D+ E P +  D
Sbjct: 122 VISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD 174



 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 20/62 (32%), Positives = 33/62 (53%)

Query: 107 VEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNK 166
           + D D + D   D +  DD+S D E+PDD+  DSE+  + S +     ++ D+ E P + 
Sbjct: 123 ISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN 182

Query: 167 KD 168
            D
Sbjct: 183 SD 184



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 3/68 (4%)

Query: 105 SEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPK 164
           SE  D + +   A DD+ DD D PD  S D S+ +S+   ++++++   ++ PD+  D  
Sbjct: 166 SEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDD---SDVPDDKSDDS 222

Query: 165 NKKDAKSN 172
           +  D  S+
Sbjct: 223 DVPDDSSD 230



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 21/61 (34%), Positives = 30/61 (49%)

Query: 108 EDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKK 167
           +D D   D + D D  DD S D + PDDS  DSE+  + S +     +  D+ E P +  
Sbjct: 210 DDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS 269

Query: 168 D 168
           D
Sbjct: 270 D 270



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 11/79 (13%)

Query: 105 SEVEDHDGEGDVAGDDDDDDDDSPDP-----ESPDDSESDSES------EKEESAEELQA 153
           S+V D   +   A DD  DD ++PD      E+PDDS  DSE+      + E S +    
Sbjct: 232 SDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDD 291

Query: 154 AEHPDEVEDPKNKKDAKSN 172
           +E  D+  D     D KS+
Sbjct: 292 SEASDDSSDDSEAPDDKSD 310



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 21/69 (30%), Positives = 38/69 (55%), Gaps = 4/69 (5%)

Query: 108 EDHDGEGDVAGDDDDD----DDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDP 163
           +D+  + +V  D+ DD    DD+S D E+PDD+  DSE+  + S +     ++ D+ + P
Sbjct: 130 DDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVP 189

Query: 164 KNKKDAKSN 172
            +  D  S+
Sbjct: 190 DDNSDDSSD 198



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 5/69 (7%)

Query: 105 SEVEDHDGEGDVAGDDDDDDDDSPDP-----ESPDDSESDSESEKEESAEELQAAEHPDE 159
           SE  D   +   A DD  DD ++PD      E+ DDS  DSE+  + S +     +  D+
Sbjct: 252 SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDD 311

Query: 160 VEDPKNKKD 168
            + P++K D
Sbjct: 312 SDVPEDKSD 320



 Score = 40.8 bits (94), Expect = 7e-04
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 5/72 (6%)

Query: 106 EVEDHDGEGDVAGDDDDDDDDSPDP-----ESPDDSESDSESEKEESAEELQAAEHPDEV 160
           EV D + +   A DD+ DD ++PD      E+PDD+  DSE+  + S +     ++ D+ 
Sbjct: 137 EVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDS 196

Query: 161 EDPKNKKDAKSN 172
            D  +   +  N
Sbjct: 197 SDDNSDDSSDDN 208



 Score = 40.4 bits (93), Expect = 9e-04
 Identities = 18/61 (29%), Positives = 33/61 (54%)

Query: 108 EDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKK 167
           +D +   D + D +  DD S D E+PDD   DS+  +++S +     ++ D++E P   +
Sbjct: 280 DDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAE 339

Query: 168 D 168
           D
Sbjct: 340 D 340



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 5/66 (7%)

Query: 108 EDHDGEGDVAGDDDDDDDDSPDPES-----PDDSESDSESEKEESAEELQAAEHPDEVED 162
           +  D   D + DD+ DD D PD +S     PDDS  DS+   + S +     +  D+ E 
Sbjct: 195 DSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEA 254

Query: 163 PKNKKD 168
           P +  D
Sbjct: 255 PDDSSD 260



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 9/69 (13%)

Query: 105 SEVEDHDGEGDVAGDDDDDDDDSPDPES-----PDDSESDSESEKEESAEELQAAEHPDE 159
           SE  D + +   A DD+ DD ++PD  S     PDD+  DS  +  + + +    ++ D+
Sbjct: 156 SEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSD----DNSDD 211

Query: 160 VEDPKNKKD 168
            + P +K D
Sbjct: 212 SDVPDDKSD 220



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 18/61 (29%), Positives = 31/61 (50%)

Query: 108 EDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKK 167
           +D +   D + D +  DD S D E+ DDS  DSE+  ++S +     +  D+ + P +  
Sbjct: 270 DDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNS 329

Query: 168 D 168
           D
Sbjct: 330 D 330



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 7/75 (9%)

Query: 105 SEVEDHDGEGDVAGDDDDDD-----DDSPDPESPDDSESDSE--SEKEESAEELQAAEHP 157
           SE  D + +   A DD+ DD     D+S D E+PDD+  DS+   +  + + +  + +  
Sbjct: 146 SEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSS 205

Query: 158 DEVEDPKNKKDAKSN 172
           D+  D  +  D KS+
Sbjct: 206 DDNSDDSDVPDDKSD 220



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 105 SEVEDHDGEGDVAGDDDDD--DDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVED 162
           S+V D D   D + D+ DD  DD+S D + PDD   DS+   + S +     +  D+ E 
Sbjct: 186 SDVPD-DNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244

Query: 163 PKNKKD 168
           P +  D
Sbjct: 245 PDDSSD 250



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 4/65 (6%)

Query: 108 EDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKK 167
           +D+  + DV  D+ DD  D    +S DD+  DS+   ++S +    ++ PD+  D  +  
Sbjct: 180 DDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDD----SDVPDDSSDDSDVP 235

Query: 168 DAKSN 172
           D  S+
Sbjct: 236 DDSSD 240



 Score = 29.6 bits (65), Expect = 1.5
 Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)

Query: 108 EDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVED 162
           ED   + DV  DD+ DD + P P     +E    S++EE  E   A    D  +D
Sbjct: 316 EDKSDDSDVP-DDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDD 369



 Score = 28.9 bits (63), Expect = 2.6
 Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 15/79 (18%)

Query: 108 EDHDGEGDVAGDDDD---------DDDDSPDPESPDDSE------SDSESEKEESAEELQ 152
           ED   EG +A D+++           D S D    D  E      SD E+  E S  +L 
Sbjct: 339 EDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLP 398

Query: 153 AAEHPDEVEDPKNKKDAKS 171
             E P  V +   K+ +K+
Sbjct: 399 TEEEPAPVVEQSGKRKSKT 417


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 17/165 (10%)

Query: 25  SNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQY 84
           S W+      +E  +K         K H    V    KS S      +D+   +E  S  
Sbjct: 565 SRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWV----KSLS-----PQDRAAYKEYISNK 615

Query: 85  QQSMDSKLSG---RYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDD----SE 137
           ++SM +KL G   +  R      SE E+ D E +   D+D++++D  + +S +D    SE
Sbjct: 616 RKSM-TKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE 674

Query: 138 SDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKSSG 182
           S SE E E+  E  +  E  D+ ED    +D +S        SSG
Sbjct: 675 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 4/113 (3%)

Query: 37  RKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRY 96
           +++   +L G   K     L     KS S     E++   +E+ E +  ++ DS   G  
Sbjct: 615 KRKSMTKLRGPNPKSSRTTL---QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671

Query: 97  RRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAE 149
                    E ED D   +   D+DDD+DD  D ++  +  S S S   +S++
Sbjct: 672 SSESS-SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 723



 Score = 34.3 bits (77), Expect = 0.061
 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 8/95 (8%)

Query: 71  EEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDP 130
           EED + +E+ E + ++  D +             S  ED   +GD   +DD+D+DD    
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDD---- 696

Query: 131 ESPDDSESDSESEKEESAEELQAAEHPDEVEDPKN 165
               D + D + + E       ++   D  +   N
Sbjct: 697 ----DEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 30.8 bits (68), Expect = 0.68
 Identities = 30/138 (21%), Positives = 50/138 (36%), Gaps = 12/138 (8%)

Query: 14  RSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEED 73
           +S SP D      +    + N+ +    LR    G    + R  +     +      +ED
Sbjct: 598 KSLSPQDRAAYKEY----ISNKRKSMTKLR----GPNPKSSRTTLQSKSESEEDDEEDED 649

Query: 74  KKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDD----DDSPD 129
            +  +E E   +    S+  G          SE  D + E D   DDD+DD    D+  +
Sbjct: 650 DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709

Query: 130 PESPDDSESDSESEKEES 147
             S   S S   S+ + +
Sbjct: 710 GSSSSSSSSGDSSDSDSN 727



 Score = 30.8 bits (68), Expect = 0.68
 Identities = 15/70 (21%), Positives = 29/70 (41%), Gaps = 6/70 (8%)

Query: 106 EVEDHDGEGDVAGDD------DDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDE 159
           E +D +G+    G D      +D+ +D  + E  D+ E D E + E+   E + +     
Sbjct: 657 EEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSS 716

Query: 160 VEDPKNKKDA 169
                +  D+
Sbjct: 717 SSGDSSDSDS 726


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 17/165 (10%)

Query: 25  SNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQY 84
           S W+      +E  +K         K H    V    KS S      +D+   +E  S  
Sbjct: 565 SRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWV----KSLS-----PQDRAAYKEYISNK 615

Query: 85  QQSMDSKLSG---RYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDD----SE 137
           ++SM +KL G   +  R      SE E+ D E +   D+D++++D  + +S +D    SE
Sbjct: 616 RKSM-TKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE 674

Query: 138 SDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKSSG 182
           S SE E E+  E  +  E  D+ ED    +D +S        SSG
Sbjct: 675 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 4/113 (3%)

Query: 37  RKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRY 96
           +++   +L G   K     L     KS S     E++   +E+ E +  ++ DS   G  
Sbjct: 615 KRKSMTKLRGPNPKSSRTTL---QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671

Query: 97  RRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAE 149
                    E ED D   +   D+DDD+DD  D ++  +  S S S   +S++
Sbjct: 672 SSESS-SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 723



 Score = 34.3 bits (77), Expect = 0.061
 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 8/95 (8%)

Query: 71  EEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDP 130
           EED + +E+ E + ++  D +             S  ED   +GD   +DD+D+DD    
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDD---- 696

Query: 131 ESPDDSESDSESEKEESAEELQAAEHPDEVEDPKN 165
               D + D + + E       ++   D  +   N
Sbjct: 697 ----DEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 30.8 bits (68), Expect = 0.68
 Identities = 30/138 (21%), Positives = 50/138 (36%), Gaps = 12/138 (8%)

Query: 14  RSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEED 73
           +S SP D      +    + N+ +    LR    G    + R  +     +      +ED
Sbjct: 598 KSLSPQDRAAYKEY----ISNKRKSMTKLR----GPNPKSSRTTLQSKSESEEDDEEDED 649

Query: 74  KKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDD----DDSPD 129
            +  +E E   +    S+  G          SE  D + E D   DDD+DD    D+  +
Sbjct: 650 DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709

Query: 130 PESPDDSESDSESEKEES 147
             S   S S   S+ + +
Sbjct: 710 GSSSSSSSSGDSSDSDSN 727



 Score = 30.8 bits (68), Expect = 0.68
 Identities = 15/70 (21%), Positives = 29/70 (41%), Gaps = 6/70 (8%)

Query: 106 EVEDHDGEGDVAGDD------DDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDE 159
           E +D +G+    G D      +D+ +D  + E  D+ E D E + E+   E + +     
Sbjct: 657 EEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSS 716

Query: 160 VEDPKNKKDA 169
                +  D+
Sbjct: 717 SSGDSSDSDS 726


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 17/165 (10%)

Query: 25  SNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQY 84
           S W+      +E  +K         K H    V    KS S      +D+   +E  S  
Sbjct: 602 SRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWV----KSLS-----PQDRAAYKEYISNK 652

Query: 85  QQSMDSKLSG---RYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDD----SE 137
           ++SM +KL G   +  R      SE E+ D E +   D+D++++D  + +S +D    SE
Sbjct: 653 RKSM-TKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE 711

Query: 138 SDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKSSG 182
           S SE E E+  E  +  E  D+ ED    +D +S        SSG
Sbjct: 712 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 756



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 4/113 (3%)

Query: 37  RKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRY 96
           +++   +L G   K     L     KS S     E++   +E+ E +  ++ DS   G  
Sbjct: 652 KRKSMTKLRGPNPKSSRTTL---QSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 708

Query: 97  RRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAE 149
                    E ED D   +   D+DDD+DD  D ++  +  S S S   +S++
Sbjct: 709 SSESS-SEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSD 760



 Score = 34.3 bits (77), Expect = 0.061
 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 8/95 (8%)

Query: 71  EEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDP 130
           EED + +E+ E + ++  D +             S  ED   +GD   +DD+D+DD    
Sbjct: 678 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDD---- 733

Query: 131 ESPDDSESDSESEKEESAEELQAAEHPDEVEDPKN 165
               D + D + + E       ++   D  +   N
Sbjct: 734 ----DEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 30.8 bits (68), Expect = 0.68
 Identities = 30/138 (21%), Positives = 50/138 (36%), Gaps = 12/138 (8%)

Query: 14  RSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEED 73
           +S SP D      +    + N+ +    LR    G    + R  +     +      +ED
Sbjct: 635 KSLSPQDRAAYKEY----ISNKRKSMTKLR----GPNPKSSRTTLQSKSESEEDDEEDED 686

Query: 74  KKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDD----DDSPD 129
            +  +E E   +    S+  G          SE  D + E D   DDD+DD    D+  +
Sbjct: 687 DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 746

Query: 130 PESPDDSESDSESEKEES 147
             S   S S   S+ + +
Sbjct: 747 GSSSSSSSSGDSSDSDSN 764



 Score = 30.8 bits (68), Expect = 0.68
 Identities = 15/70 (21%), Positives = 29/70 (41%), Gaps = 6/70 (8%)

Query: 106 EVEDHDGEGDVAGDD------DDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDE 159
           E +D +G+    G D      +D+ +D  + E  D+ E D E + E+   E + +     
Sbjct: 694 EEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSS 753

Query: 160 VEDPKNKKDA 169
                +  D+
Sbjct: 754 SSGDSSDSDS 763


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 25/59 (42%), Positives = 31/59 (52%), Gaps = 4/59 (6%)

Query: 108 EDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNK 166
           ED D E D   +DDDDD+D  D    DD E D E E+EE  E ++ A    + E  K K
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDED----DDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQK 288



 Score = 40.4 bits (93), Expect = 9e-04
 Identities = 24/98 (24%), Positives = 42/98 (42%)

Query: 71  EEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDP 130
           ++D + +EE +    +  D       +       SE ED + + D   DDDD++DDS + 
Sbjct: 150 DDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEE 209

Query: 131 ESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKD 168
                     ++ K    +    AE  DE ED +++ D
Sbjct: 210 AMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDD 247



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 12/77 (15%)

Query: 106 EVEDHDGEGDVAGDDDDDDDD-----------SPDPESPD-DSESDSESEKEESAEELQA 153
           E ED D E D   D+D+D+D+           +  P S D D E D + E ++  EE  +
Sbjct: 147 EEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDS 206

Query: 154 AEHPDEVEDPKNKKDAK 170
            E   E    K KK AK
Sbjct: 207 EEEAMETTPAKGKKAAK 223



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 17/56 (30%), Positives = 31/56 (55%)

Query: 115 DVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAK 170
           +VA D+D+++DD  + +  D+ + D + E +E  EE +  E   E    + K+ AK
Sbjct: 231 NVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAK 286



 Score = 35.0 bits (79), Expect = 0.036
 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 1/59 (1%)

Query: 111 DGEGDVAGDDDDDD-DDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKD 168
           +G+     D D+++ DDS + E  D+ E + E E E +A +  AA    E ED ++ +D
Sbjct: 136 NGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDED 194



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 8/45 (17%)

Query: 106 EVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEE 150
           E +D D + D   DD+DDDD        +D E + E E+EE  +E
Sbjct: 239 EEDDEDEDDDDDEDDEDDDD--------EDDEEEEEEEEEEPVKE 275



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 16/50 (32%), Positives = 26/50 (52%)

Query: 106 EVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAE 155
           E ED D + D   DDD+DD++  + E  +  +      K+E A++  A E
Sbjct: 243 EDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPE 292


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 8/73 (10%)

Query: 74  KKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESP 133
           ++ +EE     + S++S   G  + H        ED   + D   DDDDDDDD  D +  
Sbjct: 228 QRTDEETTDNQEGSVESSEEGEDQEH--------EDDGEDEDDEDDDDDDDDDDDDDDED 279

Query: 134 DDSESDSESEKEE 146
           D+ E D E E ++
Sbjct: 280 DEDEEDGEEENQK 292



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 2/47 (4%)

Query: 106 EVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQ 152
           E ED + E D  G+D+DD+DD  D +  DD + + + ++E+  EE Q
Sbjct: 247 EGEDQEHEDD--GEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQ 291



 Score = 30.8 bits (68), Expect = 0.68
 Identities = 12/55 (21%), Positives = 27/55 (49%), Gaps = 4/55 (7%)

Query: 113 EGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKK 167
           E    G+D + +DD  D +  DD + D + + ++  ++    E  ++ E+   K+
Sbjct: 243 ESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDD----EDEEDGEEENQKR 293



 Score = 30.4 bits (67), Expect = 0.89
 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 10/99 (10%)

Query: 73  DKKINEELESQYQQSMDSKLSGRYRRHC--GLG-FSEVEDHDGEGDVAGDDDDDDDDSPD 129
           DK I    E+  Q+  D K   R R      LG F+E E+ +      G   D       
Sbjct: 174 DKLITNTAEAVLQKMDDMKKMRRQRMRELEDLGVFNETEESNLNMYTRGKQKDI------ 227

Query: 130 PESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKD 168
            +  D+  +D++    ES+EE +  EH D+ ED  ++ D
Sbjct: 228 -QRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDD 265


>gi|42740903 MTERF domain containing 2 [Homo sapiens]
          Length = 381

 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 4/78 (5%)

Query: 69  TGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSP 128
           T  E+ ++ ++L ++ ++  +S  S   R        E ED D E D   DD+D+DDD  
Sbjct: 308 TSVEEFQVFKKLLAREEEESESSTSDDKRA----SLDEDEDDDDEEDNDEDDNDEDDDDE 363

Query: 129 DPESPDDSESDSESEKEE 146
           D +  +D++ D + ++EE
Sbjct: 364 DDDEAEDNDEDEDDDEEE 381



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 5/59 (8%)

Query: 108 EDHDGEGDVAGD-----DDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVE 161
           E+ + E   + D     D+D+DDD  +    DD++ D + E ++ AE+    E  DE E
Sbjct: 323 EEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE 381



 Score = 33.1 bits (74), Expect = 0.14
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 1/47 (2%)

Query: 105 SEVEDHDGEGDVAGDDDDDDD-DSPDPESPDDSESDSESEKEESAEE 150
           S  +D     D   DDDD++D D  D +  DD E D E+E  +  E+
Sbjct: 330 STSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDED 376


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 33/121 (27%), Positives = 48/121 (39%), Gaps = 21/121 (17%)

Query: 70  GEEDKKINEELESQ-YQQSMDSKLSGRYRRHCGLGFSEVEDHDG----EGDVAGDDDDDD 124
           G ED    EE E + Y +  D             G  + ED +G    E ++  +D+DDD
Sbjct: 95  GTEDMDEKEEDEGEEYSEDNDEP-----------GDEDEEDEEGDREEEEEIEEEDEDDD 143

Query: 125 DDSPDPESPDDSESDSESEKEESAEE-----LQAAEHPDEVEDPKNKKDAKSNYKMMFVK 179
           +D  D E  ++ E + E E+EE   E             + E   N  D   NY  +  K
Sbjct: 144 EDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAK 203

Query: 180 S 180
           S
Sbjct: 204 S 204



 Score = 27.7 bits (60), Expect = 5.7
 Identities = 14/47 (29%), Positives = 22/47 (46%)

Query: 122 DDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKD 168
           D+ DDS   E  D+ E D   E  E  +E    +  DE  D + +++
Sbjct: 88  DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEE 134


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 105 SEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPK 164
           +E E+ D E +   DD+DD+ D    ES  +SESD+E  +EE  ++    E   + E   
Sbjct: 608 NEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEG-- 665

Query: 165 NKKDAKSNYKMMFVKS 180
            K   K N     VKS
Sbjct: 666 EKTSMKLNKTTSSVKS 681



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 19/79 (24%), Positives = 37/79 (46%)

Query: 105 SEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPK 164
           S  +  D   D   DD+++D++  + +  DDS+S+S+S  E   E  +  +  D+ +D  
Sbjct: 600 SSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDES 659

Query: 165 NKKDAKSNYKMMFVKSSGS 183
           +         M   K++ S
Sbjct: 660 DSDTEGEKTSMKLNKTTSS 678



 Score = 40.8 bits (94), Expect = 7e-04
 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 4/88 (4%)

Query: 68   RTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDS 127
            +TG+ D     +L  + Q  + +   GR RR  G      +D D + D  GD+DD+D++ 
Sbjct: 1262 KTGKRDTSGGIDLGEE-QHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEED 1320

Query: 128  PDP---ESPDDSESDSESEKEESAEELQ 152
             +    +  D  E + E ++  S EEL+
Sbjct: 1321 KEDKKGKKTDICEDEDEGDQAASVEELE 1348



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 15/66 (22%), Positives = 37/66 (56%), Gaps = 1/66 (1%)

Query: 105 SEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAE-ELQAAEHPDEVEDP 163
           S++       D   D+++DD++  + +  DD   DS+SE + ++E + + +E  D+ +  
Sbjct: 596 SDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKD 655

Query: 164 KNKKDA 169
           +++ D+
Sbjct: 656 QDESDS 661



 Score = 33.1 bits (74), Expect = 0.14
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%)

Query: 124 DDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKS 171
           D D P   S  DSE  +E E+E+  EE +  +  DE +D +++ D+ S
Sbjct: 595 DSDIP---SSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNS 639



 Score = 32.3 bits (72), Expect = 0.23
 Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 23/122 (18%)

Query: 58  IGDHKSTSHFRTGEEDKKINEEL-ESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDG---- 112
           +G  KSTS   +G  ++K N+E  ++Q   +   K+  +  R   +  S   D D     
Sbjct: 197 MGQTKSTS---SGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSS 253

Query: 113 ----------EGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVED 162
                     + D   +D++++D S +    DDS+S+SE++ + + + L        + D
Sbjct: 254 DTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHG-----ISD 308

Query: 163 PK 164
           PK
Sbjct: 309 PK 310



 Score = 31.6 bits (70), Expect = 0.40
 Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 7/78 (8%)

Query: 81  ESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDS-------PDPESP 133
           +S    S DS+ S            E +D D E D +  + D + +S        D +  
Sbjct: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654

Query: 134 DDSESDSESEKEESAEEL 151
           D  ESDS++E E+++ +L
Sbjct: 655 DQDESDSDTEGEKTSMKL 672



 Score = 31.6 bits (70), Expect = 0.40
 Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 4/68 (5%)

Query: 109 DHDGEGDVAGDDDDDD----DDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPK 164
           D D       +D ++D    D+  D E  +D ESD    + +S  E       +E +D K
Sbjct: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654

Query: 165 NKKDAKSN 172
           ++ ++ S+
Sbjct: 655 DQDESDSD 662


>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
          Length = 259

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 69  TGEEDKKINEELESQYQQSMDSKL-SGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDS 127
           +G+    + E+ ES+ ++  D KL S   +R    G S+V     +  +A D+DDDDDD 
Sbjct: 112 SGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVK--LAADEDDDDDDE 169

Query: 128 PDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKSSG 182
            D +  DD +   + E EE A   ++          K+ ++ K +      +S G
Sbjct: 170 EDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKG 224


>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
          Length = 294

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 69  TGEEDKKINEELESQYQQSMDSKL-SGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDS 127
           +G+    + E+ ES+ ++  D KL S   +R    G S+V     +  +A D+DDDDDD 
Sbjct: 112 SGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVK--LAADEDDDDDDE 169

Query: 128 PDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKSSG 182
            D +  DD +   + E EE A   ++          K+ ++ K +      +S G
Sbjct: 170 EDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKG 224


>gi|111607441 hypothetical protein LOC400506 [Homo sapiens]
          Length = 458

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 3/79 (3%)

Query: 27  WEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQ 86
           W+ A   NE++K KFLRLMG  K             +  +   G   KK  + L+   Q+
Sbjct: 362 WDTAGFENEDQKLKFLRLMGGFKNLSPSFSRPASTIARPNMALG---KKAADSLQQNLQR 418

Query: 87  SMDSKLSGRYRRHCGLGFS 105
             D  +S +Y R  GLGFS
Sbjct: 419 DYDRAMSWKYSRGAGLGFS 437


>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
            sapiens]
          Length = 1826

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 9/90 (10%)

Query: 103  GFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESA---------EELQA 153
            G   + + D + DV G DD+++D  P P +P+  + D   E+E +          E+L  
Sbjct: 1707 GQGRLGEEDSDVDVEGYDDEEEDGKPKPPAPEGGDGDLADEEEGTVQQPEASVLYEDLLI 1766

Query: 154  AEHPDEVEDPKNKKDAKSNYKMMFVKSSGS 183
            +E  D+ ED  + ++  + +  + +  SGS
Sbjct: 1767 SEGEDDEEDAGSDEEGDNPFSAIQLSESGS 1796


>gi|55769587 probable nucleolar complex protein 14 [Homo sapiens]
          Length = 857

 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 14/79 (17%)

Query: 72  EDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPE 131
           +D K+N E + Q +QS ++              S+ E ++ EGD +G +D ++ DSPD  
Sbjct: 334 KDGKMNVEEDVQEEQSKEA--------------SDPESNEEEGDSSGGEDTEESDSPDSH 379

Query: 132 SPDDSESDSESEKEESAEE 150
              +S  +SE E E+ A+E
Sbjct: 380 LDLESNVESEEENEKPAKE 398


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 11/146 (7%)

Query: 28  EAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQS 87
           E  D G  E ++   R     +KE  G +  G+ +     R  EE++   EE E + ++ 
Sbjct: 789 EEGDQGEGEEEETEGR---GEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEE 845

Query: 88  MDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEE- 146
                 G      G G  E E  +GEG+  G++ + + +  + E   + E + E E+EE 
Sbjct: 846 -----EGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 900

Query: 147 --SAEELQAAEHPDEVEDPKNKKDAK 170
               EE    E  +E  + K +++ +
Sbjct: 901 EGEGEEEGEGEGEEEEGEGKGEEEGE 926



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 12/164 (7%)

Query: 19   DDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGE-EDKKIN 77
            +D  G    E  +   EE + +     G G++E  G    G+ +       GE E+++  
Sbjct: 942  EDGEGEGEEEEGEWEGEEEEGE-----GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996

Query: 78   EELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSE 137
            EE E + +   + +  G      G    EVE  +GEG+  G++++ +++  + E   + E
Sbjct: 997  EEGEEEGEGEEEGEGEGEEEEE-GEVEGEVEGEEGEGE--GEEEEGEEEGEEREKEGEGE 1053

Query: 138  SDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKSS 181
             +  + +EE  EE    ++ +  E+   ++D +   K+  +K S
Sbjct: 1054 ENRRNREEEEEEE---GKYQETGEEENERQDGEEYKKVSKIKGS 1094



 Score = 40.8 bits (94), Expect = 7e-04
 Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 10/140 (7%)

Query: 33   GNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKL 92
            G EE + +     G GK E  G    G+ +       GE+ +   EE E +++       
Sbjct: 904  GEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWE------- 956

Query: 93   SGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEK--EESAEE 150
             G      G G  E E    EG+  G++++ + +  + E  ++ E + E E+  E   EE
Sbjct: 957  -GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE 1015

Query: 151  LQAAEHPDEVEDPKNKKDAK 170
             +  E   EVE  + + + +
Sbjct: 1016 EEEGEVEGEVEGEEGEGEGE 1035



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 18/117 (15%)

Query: 46  GAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFS 105
           G GK E  G    G+ +       GEE +   EE E + +   +           G G  
Sbjct: 854 GEGKGEEEGEEGEGEEE-------GEEGEGEGEEEEGEGEGEEE-----------GEGEG 895

Query: 106 EVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVED 162
           E E+ +GEG+  G+ + ++++       +  E + E E+EE   E +  E   E E+
Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE 952



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 35/179 (19%), Positives = 70/179 (39%), Gaps = 28/179 (15%)

Query: 6   ESHPHGVKRSASPDDDLGSSNW--EAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKS 63
           E  P G       +   G+ +W  E  + G +++ +  +   G G+KE          K 
Sbjct: 648 EDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELA-------EKE 700

Query: 64  TSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDD 123
               R GEE ++   E   Q +++ + +  G           E E  +GE +    ++++
Sbjct: 701 EWKKRDGEEQEQKEREQGHQKERNQEMEEGG-----------EEEHGEGEEEEGDREEEE 749

Query: 124 DDDSPDPESPDDSESDSESEKEE--------SAEELQAAEHPDEVEDPKNKKDAKSNYK 174
           + +    E  +  E + E EKEE        + +E +  E  D+ E  + + + +   K
Sbjct: 750 EKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEK 808



 Score = 33.9 bits (76), Expect = 0.080
 Identities = 34/150 (22%), Positives = 58/150 (38%), Gaps = 29/150 (19%)

Query: 19  DDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINE 78
           +++ G    E  D   EE K+      G GK+E  G  V G+ +     R  EE     E
Sbjct: 732 EEEHGEGEEEEGDREEEEEKE------GEGKEEGEGEEVEGEREKEEGERKKEERAGKEE 785

Query: 79  ELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSES 138
           + E +  Q                G  E E+ +G G+       + ++  + E  +  E 
Sbjct: 786 KGEEEGDQ----------------GEGEEEETEGRGE-------EKEEGGEVEGGEVEEG 822

Query: 139 DSESEKEESAEELQAAEHPDEVEDPKNKKD 168
             E E+EE   E +  E   E E+ + +++
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEE 852



 Score = 33.9 bits (76), Expect = 0.080
 Identities = 32/146 (21%), Positives = 60/146 (41%), Gaps = 11/146 (7%)

Query: 6   ESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTS 65
           E    G +     +++ G    E  +   EE  ++       G+ E  G    G+ +   
Sbjct: 830 EEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE-------GEGEEEGEEGEGEGEEEE 882

Query: 66  HFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDD 125
               GEE+ +  E  E + +   + +  G      G G  E E  +GEG+  G++++ + 
Sbjct: 883 GEGEGEEEGE-GEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGE--GEEEEGEG 939

Query: 126 DSPDPESP-DDSESDSESEKEESAEE 150
           +  D E   ++ E + E E+EE   E
Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEEGEGE 965



 Score = 29.6 bits (65), Expect = 1.5
 Identities = 27/121 (22%), Positives = 47/121 (38%), Gaps = 3/121 (2%)

Query: 33  GNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKL 92
           G EE  +      G G+ E       G+ +        E + K  EE E    +  + + 
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG 937

Query: 93  SGRYRRHCGLGFSEVEDHDG---EGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAE 149
            G      G G  E  + +G   EG+  G+++ + +        ++ E + E E+EE  E
Sbjct: 938 EGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEE 997

Query: 150 E 150
           E
Sbjct: 998 E 998


>gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]
          Length = 265

 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 26/103 (25%), Positives = 43/103 (41%)

Query: 69  TGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSP 128
           +G+    + E+ ES+ ++  D KL     +    G             A +DDDDDD+  
Sbjct: 112 SGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEED 171

Query: 129 DPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKS 171
           D E  DD + D E  +E++  +        + + PK  K   S
Sbjct: 172 DDEDDDDDDFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSS 214


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 42/169 (24%), Positives = 66/169 (39%), Gaps = 27/169 (15%)

Query: 1   MSAARESHPH-GVKRSASPDDDLGSSNWEAADLG-------NEERKQKFLRLMGAGKKEH 52
           + AA E  PH G      PD+  G+      + G        E  +QKFL         H
Sbjct: 5   VGAAFEELPHDGTCDECEPDEAPGAEE-VCRECGFCYCRRHAEAHRQKFL-------SHH 56

Query: 53  TGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDG 112
               V G    T     GE   K   E++ + ++ ++S+           G     + + 
Sbjct: 57  LAEYVHGSQAWTPP-ADGEGAGKEEAEVKVEQEREIESEA----------GEESESEEES 105

Query: 113 EGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVE 161
           E +   + +++ +D  D ES +DSE + E E+E  AEE    E   E E
Sbjct: 106 ESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAE 154



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 19/66 (28%), Positives = 38/66 (57%), Gaps = 4/66 (6%)

Query: 106 EVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKN 165
           E+E   GE   + ++ + +++S   E+ ++SE +S+ E EE +EE    E   E E+  N
Sbjct: 90  EIESEAGEESESEEESESEEES---ETEEESEDESDEESEEDSEEEMEDEQESEAEE-DN 145

Query: 166 KKDAKS 171
           +++ +S
Sbjct: 146 QEEGES 151



 Score = 32.3 bits (72), Expect = 0.23
 Identities = 16/70 (22%), Positives = 35/70 (50%)

Query: 99  HCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPD 158
           H    ++   D +G G    +   + +   + E+ ++SES+ ESE EE +E  + +E   
Sbjct: 62  HGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDES 121

Query: 159 EVEDPKNKKD 168
           + E  ++ ++
Sbjct: 122 DEESEEDSEE 131



 Score = 32.0 bits (71), Expect = 0.30
 Identities = 12/54 (22%), Positives = 29/54 (53%)

Query: 119 DDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSN 172
           + +  ++   + ES  + ES++E E E+ ++E    +  +E+ED +  +  + N
Sbjct: 92  ESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDN 145



 Score = 31.2 bits (69), Expect = 0.52
 Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 4/66 (6%)

Query: 111 DGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAK 170
           DGEG  AG ++ +     + E   +SE+  ESE EE +E  + +E  +E ED  +++  +
Sbjct: 72  DGEG--AGKEEAEV--KVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEE 127

Query: 171 SNYKMM 176
            + + M
Sbjct: 128 DSEEEM 133



 Score = 30.8 bits (68), Expect = 0.68
 Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 22/121 (18%)

Query: 46  GAGKKEHTGRLV--------IGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYR 97
           GAGK+E   ++          G+   +      EE+ +  EE E +  +  +        
Sbjct: 75  GAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEED------ 128

Query: 98  RHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHP 157
                  SE E  D +   A +D+ ++ +S + E   ++ES+ + E E  AE +   + P
Sbjct: 129 -------SEEEMEDEQESEAEEDNQEEGES-EAEGETEAESEFDPEIEMEAERVAKRKCP 180

Query: 158 D 158
           D
Sbjct: 181 D 181



 Score = 29.6 bits (65), Expect = 1.5
 Identities = 19/100 (19%), Positives = 44/100 (44%), Gaps = 2/100 (2%)

Query: 71  EEDKKINEEL--ESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSP 128
           E++++I  E   ES+ ++  +S+              E  + D E ++  + + + ++  
Sbjct: 86  EQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDN 145

Query: 129 DPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKD 168
             E   ++E ++E+E E   E    AE   + + P +  D
Sbjct: 146 QEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLD 185


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 19/75 (25%), Positives = 39/75 (52%)

Query: 86  QSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKE 145
           QS++   S    +  G+   E ED + E +   +++D++++  + E  ++ E + E E+E
Sbjct: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297

Query: 146 ESAEELQAAEHPDEV 160
           E  EE +    PD +
Sbjct: 298 EEEEEEEEEAAPDVI 312



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 16/62 (25%), Positives = 36/62 (58%)

Query: 108 EDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKK 167
           E    +G ++ +++D++++  + E  +D E + E E+EE  EE +  E  +E E+ + ++
Sbjct: 247 ESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306

Query: 168 DA 169
            A
Sbjct: 307 AA 308



 Score = 26.9 bits (58), Expect = 9.8
 Identities = 13/50 (26%), Positives = 23/50 (46%)

Query: 119 DDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKD 168
           +D   ++ S         E D E E+EE  EE    E  +E E+ + +++
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEE 290


>gi|10835067 autoantigen La [Homo sapiens]
          Length = 408

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 33/129 (25%), Positives = 57/129 (44%), Gaps = 11/129 (8%)

Query: 38  KQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDS-KLSGRY 96
           K+K    +G  K  + G L + + + T     GE +K+  +++    Q+S++  K  GR 
Sbjct: 276 KEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRR 335

Query: 97  RRHCGLGFSEVEDHDGEGDV---------AGDDDDDDDDSPDPESPDDSESDSESEKEES 147
            +  G G    +   G+G V         A DD+ D+ D      P    +  E++KEE 
Sbjct: 336 FKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPV-KRAREETDKEEP 394

Query: 148 AEELQAAEH 156
           A + Q  E+
Sbjct: 395 ASKQQKTEN 403


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 117 AGDDDDDDDDSPDPESPDDSESDSE---SEKEESAEELQAAEHPDEVEDPKNKKDA 169
           A  DD+DD++S + E  ++ E + E   SE+EE  E++Q  +  DE ED + +  A
Sbjct: 433 AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAA 488



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)

Query: 129 DPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSN 172
           + +  DD ESD E E+EE  EE + A   +E ED +  ++ + +
Sbjct: 434 ETDDEDDEESDEE-EEEEEEEEEEEATDSEEEEDLEQMQEGQED 476



 Score = 27.3 bits (59), Expect = 7.5
 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 4/77 (5%)

Query: 106 EVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKN 165
           E E+ + E + A D ++++D     E  +D E   E E+EE+A      + P       N
Sbjct: 447 EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE--EDEEEEAAAGKDGDKSPMSSLQISN 504

Query: 166 KKDAKSNYKMMFVKSSG 182
           +K+ +   ++   +SSG
Sbjct: 505 EKNLEPGKQIS--RSSG 519


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 117 AGDDDDDDDDSPDPESPDDSESDSE---SEKEESAEELQAAEHPDEVEDPKNKKDA 169
           A  DD+DD++S + E  ++ E + E   SE+EE  E++Q  +  DE ED + +  A
Sbjct: 433 AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAA 488



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)

Query: 129 DPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSN 172
           + +  DD ESD E E+EE  EE + A   +E ED +  ++ + +
Sbjct: 434 ETDDEDDEESDEE-EEEEEEEEEEEATDSEEEEDLEQMQEGQED 476



 Score = 27.3 bits (59), Expect = 7.5
 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 4/77 (5%)

Query: 106 EVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKN 165
           E E+ + E + A D ++++D     E  +D E   E E+EE+A      + P       N
Sbjct: 447 EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE--EDEEEEAAAGKDGDKSPMSSLQISN 504

Query: 166 KKDAKSNYKMMFVKSSG 182
           +K+ +   ++   +SSG
Sbjct: 505 EKNLEPGKQIS--RSSG 519


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 117 AGDDDDDDDDSPDPESPDDSESDSE---SEKEESAEELQAAEHPDEVEDPKNKKDA 169
           A  DD+DD++S + E  ++ E + E   SE+EE  E++Q  +  DE ED + +  A
Sbjct: 445 AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAA 500



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)

Query: 129 DPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSN 172
           + +  DD ESD E E+EE  EE + A   +E ED +  ++ + +
Sbjct: 446 ETDDEDDEESDEE-EEEEEEEEEEEATDSEEEEDLEQMQEGQED 488



 Score = 27.3 bits (59), Expect = 7.5
 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 4/77 (5%)

Query: 106 EVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKN 165
           E E+ + E + A D ++++D     E  +D E   E E+EE+A      + P       N
Sbjct: 459 EEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE--EDEEEEAAAGKDGDKSPMSSLQISN 516

Query: 166 KKDAKSNYKMMFVKSSG 182
           +K+ +   ++   +SSG
Sbjct: 517 EKNLEPGKQIS--RSSG 531


>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
           [Homo sapiens]
          Length = 666

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 7/104 (6%)

Query: 71  EEDKKINEELESQYQQSMDSK---LSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDS 127
           +EDK  N + + + Q + D +   LS   R+   L   E  + D E  VA D+DD+  +S
Sbjct: 172 DEDKLQNSDDDEKMQNTDDEERPQLSDDERQQ--LSEEEKANSDDERPVASDNDDEKQNS 229

Query: 128 PDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKS 171
            D E P    SD E  +    E  QA++      D + ++D KS
Sbjct: 230 DDEEQP--QLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKS 271



 Score = 31.6 bits (70), Expect = 0.40
 Identities = 28/114 (24%), Positives = 43/114 (37%), Gaps = 13/114 (11%)

Query: 70  GEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPD 129
           G+  +  N+EL        DS+  G          SE  D+  E     D +D+D    D
Sbjct: 51  GDSGQPSNKELFGD-----DSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVD 105

Query: 130 PESPDDSESDSESEKEES--------AEELQAAEHPDEVEDPKNKKDAKSNYKM 175
             S  ++ +D E E   S        AE  + A   DE    ++K D   + K+
Sbjct: 106 QHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKI 159



 Score = 29.3 bits (64), Expect = 2.0
 Identities = 42/168 (25%), Positives = 60/168 (35%), Gaps = 13/168 (7%)

Query: 15  SASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKE---HTGRLVIGDHKSTSHFRTGE 71
           S + D+   S + E   L +EE+ Q           E   H+      DHKS S   +  
Sbjct: 220 SDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDS 279

Query: 72  EDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPE 131
           ED    E L  + + ++ S              S   D  G  D      D +D  P P 
Sbjct: 280 ED----EVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPG 335

Query: 132 SPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVK 179
            P D     + ++EE        E   EVE PK   D  ++  + FVK
Sbjct: 336 QPVDENGLPQDQQEEE----PIPETRIEVEIPKVNTDLGND--LYFVK 377



 Score = 28.9 bits (63), Expect = 2.6
 Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 4/56 (7%)

Query: 115 DVAGDDDDDDDDSPDPESPDDSESDSE---SEKEESAEELQAAEHPDEVEDPKNKK 167
           D+ G D D + +  D +S  DS+SD E   S    S  E    E  D  + P NK+
Sbjct: 6   DLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQ-PSNKE 60



 Score = 27.3 bits (59), Expect = 7.5
 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 4/65 (6%)

Query: 109 DHDGEGDVAGDDDDD--DDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNK 166
           D D  GD     + +   DDS D  +   S SD+ SE+ ++  E  A+E  D  ++  + 
Sbjct: 46  DQDERGDSGQPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSE--ASERSDHEDNDPSD 103

Query: 167 KDAKS 171
            D  S
Sbjct: 104 VDQHS 108



 Score = 27.3 bits (59), Expect = 7.5
 Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 10/124 (8%)

Query: 47  AGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSE 106
           +G   H+ R    D++S +  R+  ED   ++  +    ++ +      +R   G   SE
Sbjct: 75  SGSDNHSER---SDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSE 131

Query: 107 VEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAE--ELQAAEHPDEVEDPK 164
            E     G      DD+     D     D E    S+ EE A+  +    ++ D+ E  +
Sbjct: 132 AE-----GSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQ 186

Query: 165 NKKD 168
           N  D
Sbjct: 187 NTDD 190


>gi|4557509 cylicin 2 [Homo sapiens]
          Length = 348

 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 23/126 (18%)

Query: 63  STSHFRTGEEDKKINEELESQYQQSMDSKL-SGRYRRHCGLG-FSEVEDHDGEGDVAGDD 120
           S S  + G++D K  +++E   ++ +D+K  S + ++    G  S  E  D +G   G  
Sbjct: 130 SESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKG---GAK 186

Query: 121 DDDDDDSPDPESPDDSESDSESEK-----------------EESAEELQAAEHPDEVEDP 163
            D+  D  D     DS ++SE EK                 ++SA ELQA +  DE +D 
Sbjct: 187 KDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVK-ADEKKDE 245

Query: 164 KNKKDA 169
             KKDA
Sbjct: 246 DGKKDA 251



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 15/84 (17%)

Query: 106 EVEDHDGEGDVAGDDDDDD---------DDSPDPESPDDSESDS------ESEKEESAEE 150
           E +D DG+ D    D+  D             D + P  ++SDS      ES+K+ + + 
Sbjct: 241 EKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDA 300

Query: 151 LQAAEHPDEVEDPKNKKDAKSNYK 174
            + A+   E E   +KKDAK N K
Sbjct: 301 KKVAKKDTEKESADSKKDAKKNAK 324



 Score = 30.0 bits (66), Expect = 1.2
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 2/56 (3%)

Query: 121 DDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKN--KKDAKSNYK 174
           D D  D    ES  D+  D++   ++  E+  A    D  ++ K   KKDAK N K
Sbjct: 281 DSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAK 336


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 44/192 (22%), Positives = 79/192 (41%), Gaps = 28/192 (14%)

Query: 10  HGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHT------GRLVIGDHKS 63
           +G++   S  D+ G++N    + GN ++  +   +  AG  E        G  V G + S
Sbjct: 134 NGIQGQVSIIDNAGATNRSNTN-GNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNS 192

Query: 64  TSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSE---VEDHDGEGDVAGDD 120
           T +     E+   NE   S+    ++SK +G        G  E   +++ DG     G D
Sbjct: 193 TDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGAD 252

Query: 121 DDDDD---DSPDPESPDDSESDSESEKEESAEELQAAEH---------------PDEVED 162
           +D+D+   D  D E+ +  +S + S+ +E  +  +  +H               P+  ED
Sbjct: 253 EDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKED 312

Query: 163 PKNKKDAKSNYK 174
           P N+ D     K
Sbjct: 313 PHNEVDGDKTSK 324



 Score = 36.2 bits (82), Expect = 0.016
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 1/80 (1%)

Query: 105 SEVEDHDG-EGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDP 163
           S+  D D  + + + D D  D DS D    D S+S + S+  +S++   +++  D  +  
Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK 623

Query: 164 KNKKDAKSNYKMMFVKSSGS 183
            +   ++S+      KS  S
Sbjct: 624 SDSSKSESDSSDSDSKSDSS 643



 Score = 33.9 bits (76), Expect = 0.080
 Identities = 36/167 (21%), Positives = 56/167 (33%), Gaps = 20/167 (11%)

Query: 10  HGVKRSASPDDDLGSS----NWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTS 65
           +G     + DDD  S+    N ++   GN           G GK + +         S S
Sbjct: 503 NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDS--DSSDSSNS 560

Query: 66  HFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDD 125
              +   D   ++   S    S DS  S           S+ +  D        D  D  
Sbjct: 561 SDSSDSSDSDSSDSNSSSDSDSSDSDSSDS---------SDSDSSDSSNSSDSSDSSDSS 611

Query: 126 DSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSN 172
           DS D     DS+SDS   + +S++    ++  D      N  D+  N
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSD-----SNSSDSSDN 653



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 21/85 (24%), Positives = 31/85 (36%), Gaps = 2/85 (2%)

Query: 101 GLGFSEVEDHDGEGDVAGDDDDD--DDDSPDPESPDDSESDSESEKEESAEELQAAEHPD 158
           G G S+  D D        D  D  D DS D  S  DS+S      + S  +   + +  
Sbjct: 543 GKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSS 602

Query: 159 EVEDPKNKKDAKSNYKMMFVKSSGS 183
           +  D  +  D+  +      KS  S
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSS 627



 Score = 33.1 bits (74), Expect = 0.14
 Identities = 29/158 (18%), Positives = 58/158 (36%), Gaps = 21/158 (13%)

Query: 33  GNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGE--------------EDKKINE 78
           GN + + + + + G G+K   G  V   H +T      +              +D   ++
Sbjct: 412 GNVKTQGEVVNIEGPGQKSEPGNKV--GHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSD 469

Query: 79  ELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDD--- 135
           E       + +S  +   R        E +D+    D  G +DDD D + D  + D    
Sbjct: 470 ESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGN 529

Query: 136 -SESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSN 172
            +  + +++K +S +    +   D   D  N  D+  +
Sbjct: 530 GNNGNDDNDKSDSGKGKSDSSDSDS-SDSSNSSDSSDS 566



 Score = 33.1 bits (74), Expect = 0.14
 Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 6/85 (7%)

Query: 105 SEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESD----SESEKEESAEELQAAEHPD-- 158
           S+  D     D +   D D  DS      D S+SD    S+S+  +S+    +++  D  
Sbjct: 552 SDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611

Query: 159 EVEDPKNKKDAKSNYKMMFVKSSGS 183
           +  D  +  D+KS+       SS S
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDS 636



 Score = 30.8 bits (68), Expect = 0.68
 Identities = 29/163 (17%), Positives = 54/163 (33%), Gaps = 6/163 (3%)

Query: 15  SASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDK 74
           S S D    S + +++D  + +          +   + +      D   +S     +   
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN 857

Query: 75  KINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDD-----DDSPD 129
           + +    S    S DS  S           S       +   + D D  D     D S  
Sbjct: 858 RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS 917

Query: 130 PESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSN 172
             S D SES + S+   S++   +++  D   D  N  D+ ++
Sbjct: 918 SNSSDSSESSNSSDNSNSSDSSNSSDSSDS-SDSSNSSDSSNS 959



 Score = 30.4 bits (67), Expect = 0.89
 Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 1/69 (1%)

Query: 105 SEVEDHDGEGDVAGDDDDDDDDSPDP-ESPDDSESDSESEKEESAEELQAAEHPDEVEDP 163
           S+  D     + +   D  D DS D  +S + + SDS+S     + +   +    +  D 
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749

Query: 164 KNKKDAKSN 172
            N  D+  +
Sbjct: 750 SNSSDSSDS 758



 Score = 27.3 bits (59), Expect = 7.5
 Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 3/113 (2%)

Query: 63  STSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDD 122
           S+ +  + +     N    S    S DS  S           S    +  E   + D  D
Sbjct: 650 SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD 709

Query: 123 DDD-DSPDPESPDDSESD--SESEKEESAEELQAAEHPDEVEDPKNKKDAKSN 172
            D  DS D  + + S+SD  + S+  +S+    +++  D      +   + S+
Sbjct: 710 SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762


>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
          Length = 872

 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 37/113 (32%), Positives = 51/113 (45%), Gaps = 13/113 (11%)

Query: 70  GEEDKKIN---EELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDD-- 124
           G+ ++K N   E+ E   Q   DS    + ++  G G  E +  D E +        +  
Sbjct: 296 GDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRK 355

Query: 125 ---DDSPDPESPDDSESDSES-----EKEESAEELQAAEHPDEVEDPKNKKDA 169
              DDS D  S  +SES+SES     EKEE+ E L+  E P E E  K K  A
Sbjct: 356 HSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAA 408



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 3/83 (3%)

Query: 71  EEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDD---DDDDDS 127
           E D +I E+ E + Q     + S +     G G  + E    + D   +D    ++D  +
Sbjct: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSN 321

Query: 128 PDPESPDDSESDSESEKEESAEE 150
            D     + + D E +KE+S +E
Sbjct: 322 DDKTKKSEGDGDKEEKKEDSEKE 344


>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
          Length = 876

 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 37/113 (32%), Positives = 51/113 (45%), Gaps = 13/113 (11%)

Query: 70  GEEDKKIN---EELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDD-- 124
           G+ ++K N   E+ E   Q   DS    + ++  G G  E +  D E +        +  
Sbjct: 296 GDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRK 355

Query: 125 ---DDSPDPESPDDSESDSES-----EKEESAEELQAAEHPDEVEDPKNKKDA 169
              DDS D  S  +SES+SES     EKEE+ E L+  E P E E  K K  A
Sbjct: 356 HSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAA 408



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 3/83 (3%)

Query: 71  EEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDD---DDDDDS 127
           E D +I E+ E + Q     + S +     G G  + E    + D   +D    ++D  +
Sbjct: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSN 321

Query: 128 PDPESPDDSESDSESEKEESAEE 150
            D     + + D E +KE+S +E
Sbjct: 322 DDKTKKSEGDGDKEEKKEDSEKE 344


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.124    0.346 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,082,442
Number of Sequences: 37866
Number of extensions: 417865
Number of successful extensions: 8731
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 559
Number of HSP's successfully gapped in prelim test: 286
Number of HSP's that attempted gapping in prelim test: 3278
Number of HSP's gapped (non-prelim): 3243
length of query: 183
length of database: 18,247,518
effective HSP length: 96
effective length of query: 87
effective length of database: 14,612,382
effective search space: 1271277234
effective search space used: 1271277234
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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