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Search of human proteins with 7656981
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7656981 claudin 15 [Homo sapiens]
(228 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7656981 claudin 15 [Homo sapiens] 469 e-132
gi|5921465 claudin 10 isoform b [Homo sapiens] 199 2e-51
gi|183979973 claudin 19 isoform a [Homo sapiens] 161 5e-40
gi|183979975 claudin 19 isoform b [Homo sapiens] 161 5e-40
gi|33598916 claudin 10 isoform a [Homo sapiens] 155 2e-38
gi|153792186 claudin 7 [Homo sapiens] 154 8e-38
gi|4502875 claudin 3 [Homo sapiens] 145 3e-35
gi|4502877 claudin 4 [Homo sapiens] 139 3e-33
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 138 3e-33
gi|10863887 claudin 1 [Homo sapiens] 137 1e-32
gi|225703142 claudin 14 [Homo sapiens] 133 1e-31
gi|21536294 claudin 14 [Homo sapiens] 133 1e-31
gi|195947374 claudin 5 [Homo sapiens] 133 1e-31
gi|195947372 claudin 5 [Homo sapiens] 133 1e-31
gi|225703138 claudin 14 [Homo sapiens] 133 1e-31
gi|6912314 claudin 14 [Homo sapiens] 133 1e-31
gi|225703140 claudin 14 [Homo sapiens] 133 1e-31
gi|11141861 claudin 9 [Homo sapiens] 129 2e-30
gi|153792768 claudin 6 [Homo sapiens] 127 8e-30
gi|40788011 claudin 8 [Homo sapiens] 125 2e-29
gi|9966781 claudin 2 [Homo sapiens] 123 1e-28
gi|6912316 claudin 17 [Homo sapiens] 123 1e-28
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 117 6e-27
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 115 4e-26
gi|47716519 claudin 20 [Homo sapiens] 105 2e-23
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 97 1e-20
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 96 2e-20
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 96 2e-20
gi|162417973 claudin 22 [Homo sapiens] 91 6e-19
gi|10938016 claudin 11 [Homo sapiens] 90 1e-18
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 469 bits (1206), Expect = e-132
Identities = 228/228 (100%), Positives = 228/228 (100%)
Query: 1 MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVY 60
MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVY
Sbjct: 1 MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVY 60
Query: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA
Sbjct: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
Query: 121 GALHILAGICGMVAISWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGGLCLC 180
GALHILAGICGMVAISWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGGLCLC
Sbjct: 121 GALHILAGICGMVAISWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGGLCLC 180
Query: 181 SACCCGSDEDPAASARRPYQAPVSVMPVATSDQEGDSSFGKYGRNAYV 228
SACCCGSDEDPAASARRPYQAPVSVMPVATSDQEGDSSFGKYGRNAYV
Sbjct: 181 SACCCGSDEDPAASARRPYQAPVSVMPVATSDQEGDSSFGKYGRNAYV 228
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 199 bits (505), Expect = 2e-51
Identities = 104/232 (44%), Positives = 140/232 (60%), Gaps = 11/232 (4%)
Query: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYN 61
S A E F ++ G +++ TLP YW+VST+ G VITT T + NLW +C TDS GV N
Sbjct: 3 STASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSN 62
Query: 62 CWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAG 121
C +FPSMLAL GYIQACR LMI A+ LGF G + + G++CT +GG + KAK+A AG
Sbjct: 63 CKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSD-KAKAKIACLAG 121
Query: 122 ALHILAGICGMVAISWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGGLCLCS 181
+ IL+G+C M S YA IT +FFDPL+ KYELG AL++GW+ + + I+GG+ C
Sbjct: 122 IVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCF 181
Query: 182 ACCCGSDEDPAASARRPYQAPVSVMPVATSDQEGD-----SSFGKYGRNAYV 228
S D + R Y SVM T G+ + ++ +NAYV
Sbjct: 182 -----SISDNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 228
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 161 bits (407), Expect = 5e-40
Identities = 79/198 (39%), Positives = 127/198 (64%), Gaps = 5/198 (2%)
Query: 5 VETFGFFMATVGLLMLGVTLPNSYWRVSTVHGN-VITTNTIFENLWFSCATDSLGVYNCW 63
++ G+F+A G + + + W+ S+ G+ +IT ++E LW SCA+ S G C
Sbjct: 6 LQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCK 65
Query: 64 EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123
+ S+LAL G+IQ+ RALM+ A+LLGF+ ++L + G++CT +G K ++A GAL
Sbjct: 66 LYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGAL 125
Query: 124 HILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCLCSA 182
ILAG+C + A+SWYA +T++FF+P P +YE GPAL++GW+++ +++LGG LC
Sbjct: 126 FILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLC-- 183
Query: 183 CCCGSDEDPAASARRPYQ 200
C C E P +S +PY+
Sbjct: 184 CTCPEPERPNSSP-QPYR 200
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 161 bits (407), Expect = 5e-40
Identities = 79/198 (39%), Positives = 127/198 (64%), Gaps = 5/198 (2%)
Query: 5 VETFGFFMATVGLLMLGVTLPNSYWRVSTVHGN-VITTNTIFENLWFSCATDSLGVYNCW 63
++ G+F+A G + + + W+ S+ G+ +IT ++E LW SCA+ S G C
Sbjct: 6 LQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCK 65
Query: 64 EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123
+ S+LAL G+IQ+ RALM+ A+LLGF+ ++L + G++CT +G K ++A GAL
Sbjct: 66 LYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGAL 125
Query: 124 HILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCLCSA 182
ILAG+C + A+SWYA +T++FF+P P +YE GPAL++GW+++ +++LGG LC
Sbjct: 126 FILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLC-- 183
Query: 183 CCCGSDEDPAASARRPYQ 200
C C E P +S +PY+
Sbjct: 184 CTCPEPERPNSSP-QPYR 200
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 155 bits (393), Expect = 2e-38
Identities = 83/218 (38%), Positives = 127/218 (58%), Gaps = 13/218 (5%)
Query: 16 GLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWEFPSMLALSGYI 75
G L+ T ++ W+V+T +VIT +++ LW +CA ++LG ++C ++ ++GYI
Sbjct: 17 GALVAATT--SNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCRPHFTIFKVAGYI 74
Query: 76 QACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHILAGICGMVAI 135
QACR LMI A+ LGF G + + G++CT +GG + KAK+A AG + IL+G+C M
Sbjct: 75 QACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSD-KAKAKIACLAGIVFILSGLCSMTGC 133
Query: 136 SWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGGLCLCSACCCGSDEDPAASA 195
S YA IT +FFDPL+ KYELG AL++GW+ + + I+GG+ C S D +
Sbjct: 134 SLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCF-----SISDNNKTP 188
Query: 196 RRPYQAPVSVMPVATSDQEGD-----SSFGKYGRNAYV 228
R Y SVM T G+ + ++ +NAYV
Sbjct: 189 RYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 226
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 154 bits (388), Expect = 8e-38
Identities = 81/212 (38%), Positives = 125/212 (58%), Gaps = 10/212 (4%)
Query: 5 VETFGFFMATVGLLMLGVTLPNSYWRVSTVHG-NVITTNTIFENLWFSCATDSLGVYNCW 63
++ GF MA +G + L W++S+ G N+IT +++ LW C T S G+ +C
Sbjct: 6 LQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCK 65
Query: 64 EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123
+ S+LALS +QA RALM+ +++LGFL + + G++CT GG + +KA++A G +
Sbjct: 66 MYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGII 125
Query: 124 HILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCLCSA 182
I+AG+ +VA SWY I DF++PL P KYE GPA+++GW+ S + ILGG L +
Sbjct: 126 FIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALL--S 183
Query: 183 CCCGSDEDPAASARRPYQAPVSVMPVATSDQE 214
C C +E A Y+ P S P + S +E
Sbjct: 184 CSCPGNESKAG-----YRVPRS-YPKSNSSKE 209
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 145 bits (366), Expect = 3e-35
Identities = 85/212 (40%), Positives = 119/212 (56%), Gaps = 5/212 (2%)
Query: 1 MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHG-NVITTNTIFENLWFSCATDSLGV 59
MSM +E G +A +G L V WRVS G N+IT+ I+E LW +C S G
Sbjct: 1 MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQ 60
Query: 60 YNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAAT 119
C + S+LAL +QA RAL++ AILL GLL+ + G +CTN + + KAK+
Sbjct: 61 MQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNC-VQDDTAKAKITIV 119
Query: 120 AGALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLC 178
AG L +LA + +V +SW A I RDF++P+ P K E+G LY+GW+A+ + +LGG
Sbjct: 120 AGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGAL 179
Query: 179 LCSACCCGSDEDPAASARRPYQAPVSVMPVAT 210
LC C C E + + Y AP S P A+
Sbjct: 180 LC--CSCPPREKKYTATKVVYSAPRSTGPGAS 209
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 139 bits (349), Expect = 3e-33
Identities = 80/197 (40%), Positives = 117/197 (59%), Gaps = 5/197 (2%)
Query: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHG-NVITTNTIFENLWFSCATDSLGVY 60
SM ++ G +A +G L + + WRV+ G N++T+ TI+E LW +C S G
Sbjct: 3 SMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQM 62
Query: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
C + S+LAL +QA RAL+I +I++ LG+LL + G +CTN E S KAK A
Sbjct: 63 QCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDE-SAKAKTMIVA 121
Query: 121 GALHILAGICGMVAISWYAFNITRDFFDPLY-PGTKYELGPALYLGWSASLISILGGLCL 179
G + +LAG+ +V +SW A NI +DF++PL G K E+G +LY+GW+AS + +LGG L
Sbjct: 122 GVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLL 181
Query: 180 CSACCCGSDEDPAASAR 196
C C C D SA+
Sbjct: 182 C--CNCPPRTDKPYSAK 196
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 138 bits (348), Expect = 3e-33
Identities = 80/218 (36%), Positives = 117/218 (53%), Gaps = 32/218 (14%)
Query: 16 GLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWEFPSMLALSGYI 75
G L+ T ++ W+V+T +VIT +++ LW +CA GYI
Sbjct: 17 GALVAATT--SNEWKVTTRASSVITATWVYQGLWMNCA-------------------GYI 55
Query: 76 QACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHILAGICGMVAI 135
QACR LMI A+ LGF G + + G++CT +GG + + KAK+A AG + IL+G+C M
Sbjct: 56 QACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA-KAKIACLAGIVFILSGLCSMTGC 114
Query: 136 SWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGGLCLCSACCCGSDEDPAASA 195
S YA IT +FFDPL+ KYELG AL++GW+ + + I+GG+ C S D +
Sbjct: 115 SLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCF-----SISDNNKTP 169
Query: 196 RRPYQAPVSVMPVATSDQEGD-----SSFGKYGRNAYV 228
R Y SVM T G+ + ++ +NAYV
Sbjct: 170 RYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV 207
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 137 bits (344), Expect = 1e-32
Identities = 70/200 (35%), Positives = 112/200 (56%), Gaps = 5/200 (2%)
Query: 5 VETFGFFMATVGLLMLGVTLPNSYWRVSTVHG-NVITTNTIFENLWFSCATDSLGVYNCW 63
++ GF +A +G + V+ WR+ + G N++T ++E LW SC + S G C
Sbjct: 6 LQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCK 65
Query: 64 EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123
F S+L LS +QA RALM+ ILLG + + + G++C + +K ++A GA+
Sbjct: 66 VFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAI 125
Query: 124 HILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCLCSA 182
+LAG+ +VA +WY I ++F+DP+ P +YE G AL+ GW+A+ + +LGG LC +
Sbjct: 126 FLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCS 185
Query: 183 CCCGSDEDPAASARRPYQAP 202
C + P RPY P
Sbjct: 186 CPRKTTSYPTP---RPYPKP 202
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 133 bits (335), Expect = 1e-31
Identities = 76/203 (37%), Positives = 115/203 (56%), Gaps = 10/203 (4%)
Query: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWR-VSTVHGNVITTNTIFENLWFSCATDSLGVY 60
S AV+ GF ++ +G++ +T +WR + V N++T + + LW C S G+Y
Sbjct: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
Query: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
C + S+LAL +QA RALM+ + LL + + G++CT K A
Sbjct: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAILG 121
Query: 121 GALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCL 179
G L ILAG+ MVA+SW ++ ++F++PL P G K+E+G ALYLG+ +S +S++GG L
Sbjct: 122 GTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLL 181
Query: 180 CSACCCGSDEDPAASARRPYQAP 202
C +C DE P RPYQAP
Sbjct: 182 CLSC---QDEAP----YRPYQAP 197
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 133 bits (335), Expect = 1e-31
Identities = 76/203 (37%), Positives = 115/203 (56%), Gaps = 10/203 (4%)
Query: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWR-VSTVHGNVITTNTIFENLWFSCATDSLGVY 60
S AV+ GF ++ +G++ +T +WR + V N++T + + LW C S G+Y
Sbjct: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
Query: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
C + S+LAL +QA RALM+ + LL + + G++CT K A
Sbjct: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAILG 121
Query: 121 GALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCL 179
G L ILAG+ MVA+SW ++ ++F++PL P G K+E+G ALYLG+ +S +S++GG L
Sbjct: 122 GTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLL 181
Query: 180 CSACCCGSDEDPAASARRPYQAP 202
C +C DE P RPYQAP
Sbjct: 182 CLSC---QDEAP----YRPYQAP 197
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 133 bits (335), Expect = 1e-31
Identities = 82/219 (37%), Positives = 120/219 (54%), Gaps = 14/219 (6%)
Query: 2 SMAVETFGFFMATVGL--LMLGVTLPNSYWRVST-VHGNVITTNTIFENLWFSCATDSLG 58
S A+E G + VG L+L LP W+V+ + N++T T ++ LW SC S G
Sbjct: 88 SAALEILGLVLCLVGWGGLILACGLP--MWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 59 VYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAA 118
C + S+LALS +QA RAL ++A+LL F+ L + +AG +CT KA++A
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVA-PGPAKARVAL 204
Query: 119 TAGALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGL 177
T G L++ G+ +V + W+A + R+F+DP P KYELG ALY+GW+A+ + ++GG
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
Query: 178 CLCSAC--CCGSDEDPAASARRPYQAPVSVMPVATSDQE 214
LC C G P S Y AP P AT D +
Sbjct: 265 LLCCGAWVCTGR---PDLSFPVKYSAP--RRPTATGDYD 298
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 133 bits (335), Expect = 1e-31
Identities = 82/219 (37%), Positives = 120/219 (54%), Gaps = 14/219 (6%)
Query: 2 SMAVETFGFFMATVGL--LMLGVTLPNSYWRVST-VHGNVITTNTIFENLWFSCATDSLG 58
S A+E G + VG L+L LP W+V+ + N++T T ++ LW SC S G
Sbjct: 88 SAALEILGLVLCLVGWGGLILACGLP--MWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 59 VYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAA 118
C + S+LALS +QA RAL ++A+LL F+ L + +AG +CT KA++A
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVA-PGPAKARVAL 204
Query: 119 TAGALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGL 177
T G L++ G+ +V + W+A + R+F+DP P KYELG ALY+GW+A+ + ++GG
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264
Query: 178 CLCSAC--CCGSDEDPAASARRPYQAPVSVMPVATSDQE 214
LC C G P S Y AP P AT D +
Sbjct: 265 LLCCGAWVCTGR---PDLSFPVKYSAP--RRPTATGDYD 298
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 133 bits (335), Expect = 1e-31
Identities = 76/203 (37%), Positives = 115/203 (56%), Gaps = 10/203 (4%)
Query: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWR-VSTVHGNVITTNTIFENLWFSCATDSLGVY 60
S AV+ GF ++ +G++ +T +WR + V N++T + + LW C S G+Y
Sbjct: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
Query: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
C + S+LAL +QA RALM+ + LL + + G++CT K A
Sbjct: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAILG 121
Query: 121 GALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCL 179
G L ILAG+ MVA+SW ++ ++F++PL P G K+E+G ALYLG+ +S +S++GG L
Sbjct: 122 GTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLL 181
Query: 180 CSACCCGSDEDPAASARRPYQAP 202
C +C DE P RPYQAP
Sbjct: 182 CLSC---QDEAP----YRPYQAP 197
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 133 bits (335), Expect = 1e-31
Identities = 76/203 (37%), Positives = 115/203 (56%), Gaps = 10/203 (4%)
Query: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWR-VSTVHGNVITTNTIFENLWFSCATDSLGVY 60
S AV+ GF ++ +G++ +T +WR + V N++T + + LW C S G+Y
Sbjct: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
Query: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
C + S+LAL +QA RALM+ + LL + + G++CT K A
Sbjct: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAILG 121
Query: 121 GALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCL 179
G L ILAG+ MVA+SW ++ ++F++PL P G K+E+G ALYLG+ +S +S++GG L
Sbjct: 122 GTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLL 181
Query: 180 CSACCCGSDEDPAASARRPYQAP 202
C +C DE P RPYQAP
Sbjct: 182 CLSC---QDEAP----YRPYQAP 197
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 133 bits (335), Expect = 1e-31
Identities = 76/203 (37%), Positives = 115/203 (56%), Gaps = 10/203 (4%)
Query: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWR-VSTVHGNVITTNTIFENLWFSCATDSLGVY 60
S AV+ GF ++ +G++ +T +WR + V N++T + + LW C S G+Y
Sbjct: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
Query: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
C + S+LAL +QA RALM+ + LL + + G++CT K A
Sbjct: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRC-AKGTPAKTTFAILG 121
Query: 121 GALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCL 179
G L ILAG+ MVA+SW ++ ++F++PL P G K+E+G ALYLG+ +S +S++GG L
Sbjct: 122 GTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLL 181
Query: 180 CSACCCGSDEDPAASARRPYQAP 202
C +C DE P RPYQAP
Sbjct: 182 CLSC---QDEAP----YRPYQAP 197
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 129 bits (324), Expect = 2e-30
Identities = 72/184 (39%), Positives = 104/184 (56%), Gaps = 3/184 (1%)
Query: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGN-VITTNTIFENLWFSCATDSLGVY 60
S +E G +A +G L V+ W+V+ GN ++ ++E LW SC S G
Sbjct: 3 STGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQM 62
Query: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
C + S+LAL +QA RAL + A+LL LGLL+ I G +CT E KA++ TA
Sbjct: 63 QCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDE-GAKARIVLTA 121
Query: 121 GALHILAGICGMVAISWYAFNITRDFFDPLY-PGTKYELGPALYLGWSASLISILGGLCL 179
G + +LAGI ++ + W A I +DF++PL K ELG +LYLGW+A+ + +LGG L
Sbjct: 122 GVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLL 181
Query: 180 CSAC 183
C C
Sbjct: 182 CCTC 185
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 127 bits (319), Expect = 8e-30
Identities = 71/195 (36%), Positives = 107/195 (54%), Gaps = 15/195 (7%)
Query: 12 MATVGLLMLGVTLPN------------SYWRVSTVHGN-VITTNTIFENLWFSCATDSLG 58
MA+ G+ +LGV L W+V+ GN ++ ++E LW SC S G
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 59 VYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAA 118
C + S+LAL +QA RAL + A+L+ GLL+ +AG +CT E KA+L
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVE-EKDSKARLVL 119
Query: 119 TAGALHILAGICGMVAISWYAFNITRDFFDPLY-PGTKYELGPALYLGWSASLISILGGL 177
T+G + +++G+ ++ + W A I RDF++PL K ELG +LYLGW+AS + +LGG
Sbjct: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG 179
Query: 178 CLCSACCCGSDEDPA 192
LC C G + P+
Sbjct: 180 LLCCTCPSGGSQGPS 194
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 125 bits (315), Expect = 2e-29
Identities = 76/227 (33%), Positives = 111/227 (48%), Gaps = 8/227 (3%)
Query: 4 AVETFGFFMATVGLLMLGVTLPNSYWRVST-VHGNVITTNTIFENLWFSCATDSLGVYNC 62
A+E G F+ VG++ WRVS + N++ +E LW +C + C
Sbjct: 5 ALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQC 64
Query: 63 WEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGA 122
+ S+LALS +QA R LM A ++ FL ++ I G++CT G KA + TAG
Sbjct: 65 KIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGI 124
Query: 123 LHILAGICGMVAISWYAFNITRDFFDPLY-PGTKYELGPALYLGWSASLISILGGLCLCS 181
+ I+ G+ ++ +SW A I RDF++ + K ELG ALYLGW+ +L+ I+GG C
Sbjct: 125 IFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGALFCC 184
Query: 182 ACCCGSDEDPAASARRPYQAPVSVMPVATSDQEGDSSFGKYGRNAYV 228
CC S+ Y P S S G S Y R+ YV
Sbjct: 185 VFCCNE-----KSSSYRYSIP-SHRTTQKSYHTGKKSPSVYSRSQYV 225
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 123 bits (308), Expect = 1e-28
Identities = 71/229 (31%), Positives = 113/229 (49%), Gaps = 3/229 (1%)
Query: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIF-ENLWFSCATDSLGVY 60
S+ ++ G+ + +GLL V + W+ S+ G I T F + LW CAT S G+
Sbjct: 3 SLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGIT 62
Query: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
C + ++L L IQA +A+M+T+ + L ++ + G+RCT + E K ++A
Sbjct: 63 QCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCT-VFCQESRAKDRVAVAG 121
Query: 121 GALHILAGICGMVAISWYAFNITRDFFDPLYPGT-KYELGPALYLGWSASLISILGGLCL 179
G IL G+ G + ++W I RDF+ PL P + K+E+G ALYLG +SL S++ G+ L
Sbjct: 122 GVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIIL 181
Query: 180 CSACCCGSDEDPAASARRPYQAPVSVMPVATSDQEGDSSFGKYGRNAYV 228
C +C + A + P + S F Y YV
Sbjct: 182 CFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV 230
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 123 bits (308), Expect = 1e-28
Identities = 76/220 (34%), Positives = 115/220 (52%), Gaps = 12/220 (5%)
Query: 11 FMATVGLLMLGVTLPNSYWRVSTVHG-NVITTNTIFENLWFSCATDSLGVYNCWEFPSML 69
F+ VG L + LP WRVS G N+I ++E LW +C + C + S+L
Sbjct: 15 FLGMVGTLATTL-LPQ--WRVSAFVGSNIIVFERLWEGLWMNCIRQARVRLQCKFYSSLL 71
Query: 70 ALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHILAGI 129
AL ++ RALM A+ L + LL+GI G++ G KA L T+G L IL GI
Sbjct: 72 ALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVLFILTGI 131
Query: 130 CGMVAISWYAFNITRDFFDP-LYPGTKYELGPALYLGWSASLISILGGLCLCSACCCGSD 188
++ +SW A I RDF++P ++ G K ELG AL+LGW+++ + +GG LC CCC
Sbjct: 132 FVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGGLLCGFCCCN-- 189
Query: 189 EDPAASARRPYQAPVSVMPVATSDQEGDSSFGKYGRNAYV 228
++ Y+ PV V +D+ +++ +YV
Sbjct: 190 -----RKKQGYRYPVPGYRVPHTDKRRNTTMLSKTSTSYV 224
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 117 bits (294), Expect = 6e-27
Identities = 61/192 (31%), Positives = 104/192 (54%), Gaps = 12/192 (6%)
Query: 4 AVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCW 63
A + GF ++ +G+ + W ++ N +T ++ LW SC +S G C
Sbjct: 5 ACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECR 64
Query: 64 EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123
+ ++L L +QA RALMI I+LG +GLL+ I L+C IG +E S KA + T+G +
Sbjct: 65 GYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIM 124
Query: 124 HILAGICGMVAISWYAFNITRDFF---DPLYPG---------TKYELGPALYLGWSASLI 171
I++G+C + +S +A + +F+ +Y G T+Y G AL++GW A +
Sbjct: 125 FIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGL 184
Query: 172 SILGGLCLCSAC 183
+++GG+ +C AC
Sbjct: 185 TLIGGVMMCIAC 196
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 115 bits (287), Expect = 4e-26
Identities = 61/190 (32%), Positives = 101/190 (53%), Gaps = 12/190 (6%)
Query: 6 ETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWEF 65
+ F ++ +GL W ++ N +T+ +E LW SC S G C +
Sbjct: 7 QVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTECRPY 66
Query: 66 PSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHI 125
++L L +QA RALMI I+LG +GLL+ I L+C IG +E S KA + T+G + I
Sbjct: 67 FTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFI 126
Query: 126 LAGICGMVAISWYAFNITRDFF---DPLYPG---------TKYELGPALYLGWSASLISI 173
++G+C + +S +A + +F+ +Y G T+Y G AL++GW A +++
Sbjct: 127 VSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTL 186
Query: 174 LGGLCLCSAC 183
+GG+ +C AC
Sbjct: 187 IGGVMMCIAC 196
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 105 bits (263), Expect = 2e-23
Identities = 62/207 (29%), Positives = 106/207 (51%), Gaps = 10/207 (4%)
Query: 2 SMAVETFGFFMATVGL--LMLGVTLPNSYWRVST-VHGNVITTNTIFENLWFSCATDSLG 58
S ++ F +A G+ ++ LPN W+V+ V N+IT LW C S G
Sbjct: 3 SAGLQLLAFILALSGVSGVLTATLLPN--WKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
Query: 59 VYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAA 118
+++C S+L+L ++QA RA M+ A +L LG+ G++CT +GG + K+ +
Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGG-DRETKSHASF 119
Query: 119 TAGALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGL 177
G + AGI +++ WY I +F D P K+E G A+Y+G+ ++++ + G+
Sbjct: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179
Query: 178 CLCSACCCGSDEDPAASARRPYQAPVS 204
C++C +P A P Q P+S
Sbjct: 180 IFCTSCI---KRNPEARLDPPTQQPIS 203
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 96.7 bits (239), Expect = 1e-20
Identities = 60/186 (32%), Positives = 93/186 (50%), Gaps = 5/186 (2%)
Query: 4 AVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCW 63
A+++ G ++ +G ++ +T +W+ + N + T+ LW +C C
Sbjct: 8 AMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQCK 65
Query: 64 EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123
+F S LAL ++ R LM + LGFLGLL+ GL C IG + K +L G L
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 124 HILAGICGMVAISWYAFNITRDFFDPLYPG--TKYELGPALYLGWSASLISILGGLCLCS 181
+GI +V +SW A ++F+D P ++E G AL+LGW A L +LGG CL +
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG-CLLN 184
Query: 182 ACCCGS 187
C S
Sbjct: 185 CAACSS 190
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 96.3 bits (238), Expect = 2e-20
Identities = 60/186 (32%), Positives = 93/186 (50%), Gaps = 5/186 (2%)
Query: 4 AVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCW 63
A+++ G ++ +G ++ +T +W+ + N + T+ LW +C C
Sbjct: 8 AMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQCK 65
Query: 64 EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123
+F S LAL ++ R LM + LGFLGLL+ GL C IG + K +L G L
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 124 HILAGICGMVAISWYAFNITRDFFDPLYPG--TKYELGPALYLGWSASLISILGGLCLCS 181
+GI +V +SW A ++F+D P ++E G AL+LGW A L +LGG CL +
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG-CLLN 184
Query: 182 ACCCGS 187
C S
Sbjct: 185 CAACSS 190
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 96.3 bits (238), Expect = 2e-20
Identities = 60/186 (32%), Positives = 93/186 (50%), Gaps = 5/186 (2%)
Query: 4 AVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCW 63
A+++ G ++ +G ++ +T +W+ + N + T+ LW +C C
Sbjct: 8 AMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQCK 65
Query: 64 EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123
+F S LAL ++ R LM + LGFLGLL+ GL C IG + K +L G L
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 124 HILAGICGMVAISWYAFNITRDFFDPLYPG--TKYELGPALYLGWSASLISILGGLCLCS 181
+GI +V +SW A ++F+D P ++E G AL+LGW A L +LGG CL +
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG-CLLN 184
Query: 182 ACCCGS 187
C S
Sbjct: 185 CAACSS 190
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 91.3 bits (225), Expect = 6e-19
Identities = 62/189 (32%), Positives = 93/189 (49%), Gaps = 8/189 (4%)
Query: 9 GFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWEFPSM 68
G ++ +G ++ +T +W+ + N + T+ LW +C C +F S
Sbjct: 13 GVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKDFDSF 70
Query: 69 LALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHILAG 128
LAL ++ R LM + LGFLGLL+ GL C IG + K +L G L +G
Sbjct: 71 LALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILSWASG 130
Query: 129 ICGMVAISWYAFNITRDFFDPLYPG--TKYELGPALYLGWSASLISILGGLCL-CSACCC 185
+ +V +SW A ++F+D P ++E G AL+LGW A L +LGG L C+AC
Sbjct: 131 VTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCAAC-- 188
Query: 186 GSDEDPAAS 194
S P AS
Sbjct: 189 -SSHAPLAS 196
>gi|10938016 claudin 11 [Homo sapiens]
Length = 207
Score = 90.1 bits (222), Expect = 1e-18
Identities = 64/205 (31%), Positives = 94/205 (45%), Gaps = 16/205 (7%)
Query: 1 MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFE----NLWFSCATDS 56
++ ++ GF + VG + + VT + W V T + T + E LW C +
Sbjct: 2 VATCLQVVGFVTSFVGWIGVIVTTSTNDW-VVTCGYTIPTCRKLDELGSKGLWADCVM-A 59
Query: 57 LGVYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKL 116
G+Y+C +L L GY+QACRALMI A +LG +LL + L C +G K +
Sbjct: 60 TGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRR 119
Query: 117 AATAGALHILAGICGMVAISWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGG 176
A AG L IL +C +VA W+ R+ T G +LY GW +++ ++GG
Sbjct: 120 AQLAGVLLILLALCALVATIWFPVCAHRE-------TTIVSFGYSLYAGWIGAVLCLVGG 172
Query: 177 LCLCSACCCGSDEDPAASARRPYQA 201
C CC D R Y A
Sbjct: 173 ---CVILCCAGDAQAFGENRFYYTA 194
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,204,782
Number of Sequences: 37866
Number of extensions: 333099
Number of successful extensions: 1280
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 1156
Number of HSP's gapped (non-prelim): 93
length of query: 228
length of database: 18,247,518
effective HSP length: 99
effective length of query: 129
effective length of database: 14,498,784
effective search space: 1870343136
effective search space used: 1870343136
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.