BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo sapiens] (2316 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo sa... 4638 0.0 gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo sa... 4624 0.0 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 55 6e-07 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 54 1e-06 gi|118498362 kinectin 1 isoform b [Homo sapiens] 54 2e-06 gi|118498368 kinectin 1 isoform c [Homo sapiens] 54 2e-06 gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 53 4e-06 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 53 4e-06 gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 52 7e-06 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 52 9e-06 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 50 3e-05 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 50 3e-05 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 50 3e-05 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 49 4e-05 gi|71061468 centromere protein E [Homo sapiens] 49 4e-05 gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 49 4e-05 gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 49 7e-05 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 47 2e-04 gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 47 2e-04 gi|21735548 centrosomal protein 2 [Homo sapiens] 47 2e-04 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 47 2e-04 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 47 2e-04 gi|4758650 kinesin family member 5C [Homo sapiens] 47 3e-04 gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 46 4e-04 gi|87298937 centrosomal protein 110kDa [Homo sapiens] 46 4e-04 gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 46 5e-04 gi|55770834 centromere protein F [Homo sapiens] 45 6e-04 gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 45 6e-04 gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo... 45 6e-04 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 45 8e-04 >gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo sapiens] Length = 2316 Score = 4638 bits (12031), Expect = 0.0 Identities = 2316/2316 (100%), Positives = 2316/2316 (100%) Query: 1 MDGVSSEANEENDNIERPVRRRHSSILKPPRSPLQDLRGGNERVQESNALRNKKNSRRVS 60 MDGVSSEANEENDNIERPVRRRHSSILKPPRSPLQDLRGGNERVQESNALRNKKNSRRVS Sbjct: 1 MDGVSSEANEENDNIERPVRRRHSSILKPPRSPLQDLRGGNERVQESNALRNKKNSRRVS 60 Query: 61 FADTIKVFQTESHMKIVRKSEMEETETGENLLLIQNKKLEDNYCEITGMNTLLSAPIHTQ 120 FADTIKVFQTESHMKIVRKSEMEETETGENLLLIQNKKLEDNYCEITGMNTLLSAPIHTQ Sbjct: 61 FADTIKVFQTESHMKIVRKSEMEETETGENLLLIQNKKLEDNYCEITGMNTLLSAPIHTQ 120 Query: 121 MQQKEFSIIEHTRERKHANDQTVIFSDENQMDLTSSHTVMITKGLLDNPISEKSTKIDTT 180 MQQKEFSIIEHTRERKHANDQTVIFSDENQMDLTSSHTVMITKGLLDNPISEKSTKIDTT Sbjct: 121 MQQKEFSIIEHTRERKHANDQTVIFSDENQMDLTSSHTVMITKGLLDNPISEKSTKIDTT 180 Query: 181 SFLANLKLHTEDSRMKKEVNFSVDQNTSSENKIDFNDFIKRLKTGKCSAFPDVPDKENFE 240 SFLANLKLHTEDSRMKKEVNFSVDQNTSSENKIDFNDFIKRLKTGKCSAFPDVPDKENFE Sbjct: 181 SFLANLKLHTEDSRMKKEVNFSVDQNTSSENKIDFNDFIKRLKTGKCSAFPDVPDKENFE 240 Query: 241 IPIYSKEPNSASSTHQMHVSLKEDENNSNITRLFREKDDGMNFTQCHTANIQTLIPTSSE 300 IPIYSKEPNSASSTHQMHVSLKEDENNSNITRLFREKDDGMNFTQCHTANIQTLIPTSSE Sbjct: 241 IPIYSKEPNSASSTHQMHVSLKEDENNSNITRLFREKDDGMNFTQCHTANIQTLIPTSSE 300 Query: 301 TNSRESKGNDITIYGNDFMDLTFNHTLQILPATGNFSEIENQTQNAMDVTTGYGTKASGN 360 TNSRESKGNDITIYGNDFMDLTFNHTLQILPATGNFSEIENQTQNAMDVTTGYGTKASGN Sbjct: 301 TNSRESKGNDITIYGNDFMDLTFNHTLQILPATGNFSEIENQTQNAMDVTTGYGTKASGN 360 Query: 361 KTVFKSKQNTAFQDLSINSADKIHITRSHIMGAETHIVSQTCNQDARILAMTPESIYSNP 420 KTVFKSKQNTAFQDLSINSADKIHITRSHIMGAETHIVSQTCNQDARILAMTPESIYSNP Sbjct: 361 KTVFKSKQNTAFQDLSINSADKIHITRSHIMGAETHIVSQTCNQDARILAMTPESIYSNP 420 Query: 421 SIQGCKTVFYSSCNDAMEMTKCLSNMREEKNLLKHDSNYAKMYCNPDAMSSLTEKTIYSG 480 SIQGCKTVFYSSCNDAMEMTKCLSNMREEKNLLKHDSNYAKMYCNPDAMSSLTEKTIYSG Sbjct: 421 SIQGCKTVFYSSCNDAMEMTKCLSNMREEKNLLKHDSNYAKMYCNPDAMSSLTEKTIYSG 480 Query: 481 EENMDITKSHTVAIDNQIFKQDQSNVQIAAAPTPEKEMMLQNLMTTSEDGKMNVNCNSVP 540 EENMDITKSHTVAIDNQIFKQDQSNVQIAAAPTPEKEMMLQNLMTTSEDGKMNVNCNSVP Sbjct: 481 EENMDITKSHTVAIDNQIFKQDQSNVQIAAAPTPEKEMMLQNLMTTSEDGKMNVNCNSVP 540 Query: 541 HVSKERIQQSLSNPLSISLTDRKTELLSGENMDLTESHTSNLGSQVPLAAYNLAPESTSE 600 HVSKERIQQSLSNPLSISLTDRKTELLSGENMDLTESHTSNLGSQVPLAAYNLAPESTSE Sbjct: 541 HVSKERIQQSLSNPLSISLTDRKTELLSGENMDLTESHTSNLGSQVPLAAYNLAPESTSE 600 Query: 601 SHSQSKSSSDECEEITKSRNEPFQRSDIIAKNSLTDTWNKDKDWVLKILPYLDKDSPQSA 660 SHSQSKSSSDECEEITKSRNEPFQRSDIIAKNSLTDTWNKDKDWVLKILPYLDKDSPQSA Sbjct: 601 SHSQSKSSSDECEEITKSRNEPFQRSDIIAKNSLTDTWNKDKDWVLKILPYLDKDSPQSA 660 Query: 661 DCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQSLFSTTKPLFSSGQFSMKNHDTAISSH 720 DCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQSLFSTTKPLFSSGQFSMKNHDTAISSH Sbjct: 661 DCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQSLFSTTKPLFSSGQFSMKNHDTAISSH 720 Query: 721 TVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMIICSEEEQNMDLTKSHTVVIGFGPSELQ 780 TVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMIICSEEEQNMDLTKSHTVVIGFGPSELQ Sbjct: 721 TVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMIICSEEEQNMDLTKSHTVVIGFGPSELQ 780 Query: 781 ELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIEKSGVLKSNCIMDVLEDESVQKPKFPK 840 ELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIEKSGVLKSNCIMDVLEDESVQKPKFPK Sbjct: 781 ELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIEKSGVLKSNCIMDVLEDESVQKPKFPK 840 Query: 841 EKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDITKSYTIEINHRPLLEKRDCHLVPLAG 900 EKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDITKSYTIEINHRPLLEKRDCHLVPLAG Sbjct: 841 EKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDITKSYTIEINHRPLLEKRDCHLVPLAG 900 Query: 901 TSETILYTCGQDDMEITRSHTTALECKTVSPDEITTRPMDKTVVFVDNHVELEMTESHTV 960 TSETILYTCGQDDMEITRSHTTALECKTVSPDEITTRPMDKTVVFVDNHVELEMTESHTV Sbjct: 901 TSETILYTCGQDDMEITRSHTTALECKTVSPDEITTRPMDKTVVFVDNHVELEMTESHTV 960 Query: 961 FIDYQEKERTDRPNFELSQRKSLGTPTVICTPTEESVFFPGNGESDRLVANDSQLTPLEE 1020 FIDYQEKERTDRPNFELSQRKSLGTPTVICTPTEESVFFPGNGESDRLVANDSQLTPLEE Sbjct: 961 FIDYQEKERTDRPNFELSQRKSLGTPTVICTPTEESVFFPGNGESDRLVANDSQLTPLEE 1020 Query: 1021 WSNNRGPVEVADNMELSKSATCKNIKDVQSPGFLNEPLSSKSQRRKSLKLKNDKTIVFSE 1080 WSNNRGPVEVADNMELSKSATCKNIKDVQSPGFLNEPLSSKSQRRKSLKLKNDKTIVFSE Sbjct: 1021 WSNNRGPVEVADNMELSKSATCKNIKDVQSPGFLNEPLSSKSQRRKSLKLKNDKTIVFSE 1080 Query: 1081 NHKNDMDITQSCMVEIDNESALEDKEDFHLAGASKTILYSCGQDDMEITRSHTTALECKT 1140 NHKNDMDITQSCMVEIDNESALEDKEDFHLAGASKTILYSCGQDDMEITRSHTTALECKT Sbjct: 1081 NHKNDMDITQSCMVEIDNESALEDKEDFHLAGASKTILYSCGQDDMEITRSHTTALECKT 1140 Query: 1141 LLPNEIAIRPMDKTVLFTDNYSDLEVTDSHTVFIDCQATEKILEENPKFGIGKGKNLGVS 1200 LLPNEIAIRPMDKTVLFTDNYSDLEVTDSHTVFIDCQATEKILEENPKFGIGKGKNLGVS Sbjct: 1141 LLPNEIAIRPMDKTVLFTDNYSDLEVTDSHTVFIDCQATEKILEENPKFGIGKGKNLGVS 1200 Query: 1201 FPKDNSCVQEIAEKQALAVGNKIVLHTEQKQQLFAATNRTTNEIIKFHSAAMDEKVIGKV 1260 FPKDNSCVQEIAEKQALAVGNKIVLHTEQKQQLFAATNRTTNEIIKFHSAAMDEKVIGKV Sbjct: 1201 FPKDNSCVQEIAEKQALAVGNKIVLHTEQKQQLFAATNRTTNEIIKFHSAAMDEKVIGKV 1260 Query: 1261 VDQACTLEKAQVESCQLNNRDRRNVDFTSSHATAVCGSSDNYSCLPNVISCTDNLEGSAM 1320 VDQACTLEKAQVESCQLNNRDRRNVDFTSSHATAVCGSSDNYSCLPNVISCTDNLEGSAM Sbjct: 1261 VDQACTLEKAQVESCQLNNRDRRNVDFTSSHATAVCGSSDNYSCLPNVISCTDNLEGSAM 1320 Query: 1321 LLCDKDEEKANYCPVQNDLAYANDFASEYYLESEGQPLSAPCPLLEKEEVIQTSTKGQLD 1380 LLCDKDEEKANYCPVQNDLAYANDFASEYYLESEGQPLSAPCPLLEKEEVIQTSTKGQLD Sbjct: 1321 LLCDKDEEKANYCPVQNDLAYANDFASEYYLESEGQPLSAPCPLLEKEEVIQTSTKGQLD 1380 Query: 1381 CVITLHKDQDLIKDPRNLLANQTLVYSQDLGEMTKLNSKRVSFKLPKDQMKVYVDDIYVI 1440 CVITLHKDQDLIKDPRNLLANQTLVYSQDLGEMTKLNSKRVSFKLPKDQMKVYVDDIYVI Sbjct: 1381 CVITLHKDQDLIKDPRNLLANQTLVYSQDLGEMTKLNSKRVSFKLPKDQMKVYVDDIYVI 1440 Query: 1441 PQPHFSTDQPPLPKKGQSSINKEEVILSKAGNKSLNIIENSSAPICENKPKILNSEEWFA 1500 PQPHFSTDQPPLPKKGQSSINKEEVILSKAGNKSLNIIENSSAPICENKPKILNSEEWFA Sbjct: 1441 PQPHFSTDQPPLPKKGQSSINKEEVILSKAGNKSLNIIENSSAPICENKPKILNSEEWFA 1500 Query: 1501 AACKKELKENIQTTNYNTALDFHSNSDVTKQVIQTHVNAGEAPDPVITSNVPCFHSIKPN 1560 AACKKELKENIQTTNYNTALDFHSNSDVTKQVIQTHVNAGEAPDPVITSNVPCFHSIKPN Sbjct: 1501 AACKKELKENIQTTNYNTALDFHSNSDVTKQVIQTHVNAGEAPDPVITSNVPCFHSIKPN 1560 Query: 1561 LNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAHNDMHIVQATEIHNINIISSNAKDSRD 1620 LNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAHNDMHIVQATEIHNINIISSNAKDSRD Sbjct: 1561 LNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAHNDMHIVQATEIHNINIISSNAKDSRD 1620 Query: 1621 EENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFLPRLPNKRNCSVTGIDDLEQIPADTTD 1680 EENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFLPRLPNKRNCSVTGIDDLEQIPADTTD Sbjct: 1621 EENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFLPRLPNKRNCSVTGIDDLEQIPADTTD 1680 Query: 1681 INHLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEKALIE 1740 INHLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEKALIE Sbjct: 1681 INHLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEKALIE 1740 Query: 1741 TYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEE 1800 TYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEE Sbjct: 1741 TYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEE 1800 Query: 1801 DIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLR 1860 DIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLR Sbjct: 1801 DIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLR 1860 Query: 1861 EKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIY 1920 EKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIY Sbjct: 1861 EKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIY 1920 Query: 1921 REDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTK 1980 REDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTK Sbjct: 1921 REDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTK 1980 Query: 1981 MTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEE 2040 MTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEE Sbjct: 1981 MTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEE 2040 Query: 2041 KNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEEL 2100 KNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEEL Sbjct: 2041 KNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEEL 2100 Query: 2101 LDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNFQSLL 2160 LDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNFQSLL Sbjct: 2101 LDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNFQSLL 2160 Query: 2161 DEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQLPKMLEEFSLVVHHCRLLGEEIEYL 2220 DEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQLPKMLEEFSLVVHHCRLLGEEIEYL Sbjct: 2161 DEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQLPKMLEEFSLVVHHCRLLGEEIEYL 2220 Query: 2221 KRWGPNYNLMNIDINNNELRLLFSSSAAFAKFEITLFLSAYYPSVPLPSTIQNHVGNTSQ 2280 KRWGPNYNLMNIDINNNELRLLFSSSAAFAKFEITLFLSAYYPSVPLPSTIQNHVGNTSQ Sbjct: 2221 KRWGPNYNLMNIDINNNELRLLFSSSAAFAKFEITLFLSAYYPSVPLPSTIQNHVGNTSQ 2280 Query: 2281 DDIATILSKVPLENNYLKNVVKQIYQDLFQDCHFYH 2316 DDIATILSKVPLENNYLKNVVKQIYQDLFQDCHFYH Sbjct: 2281 DDIATILSKVPLENNYLKNVVKQIYQDLFQDCHFYH 2316 >gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo sapiens] Length = 2342 Score = 4624 bits (11994), Expect = 0.0 Identities = 2316/2342 (98%), Positives = 2316/2342 (98%), Gaps = 26/2342 (1%) Query: 1 MDGVSSEANEENDNIERPVRRRHSSILKPPRSPLQDLRGGNERVQESNALRNKKNSRRVS 60 MDGVSSEANEENDNIERPVRRRHSSILKPPRSPLQDLRGGNERVQESNALRNKKNSRRVS Sbjct: 1 MDGVSSEANEENDNIERPVRRRHSSILKPPRSPLQDLRGGNERVQESNALRNKKNSRRVS 60 Query: 61 FADTIKVFQTESHMKIVRKSEME--------------------------ETETGENLLLI 94 FADTIKVFQTESHMKIVRKSEME ETETGENLLLI Sbjct: 61 FADTIKVFQTESHMKIVRKSEMEGCSAMVPSQLQLLPPGFKRFSCLSLPETETGENLLLI 120 Query: 95 QNKKLEDNYCEITGMNTLLSAPIHTQMQQKEFSIIEHTRERKHANDQTVIFSDENQMDLT 154 QNKKLEDNYCEITGMNTLLSAPIHTQMQQKEFSIIEHTRERKHANDQTVIFSDENQMDLT Sbjct: 121 QNKKLEDNYCEITGMNTLLSAPIHTQMQQKEFSIIEHTRERKHANDQTVIFSDENQMDLT 180 Query: 155 SSHTVMITKGLLDNPISEKSTKIDTTSFLANLKLHTEDSRMKKEVNFSVDQNTSSENKID 214 SSHTVMITKGLLDNPISEKSTKIDTTSFLANLKLHTEDSRMKKEVNFSVDQNTSSENKID Sbjct: 181 SSHTVMITKGLLDNPISEKSTKIDTTSFLANLKLHTEDSRMKKEVNFSVDQNTSSENKID 240 Query: 215 FNDFIKRLKTGKCSAFPDVPDKENFEIPIYSKEPNSASSTHQMHVSLKEDENNSNITRLF 274 FNDFIKRLKTGKCSAFPDVPDKENFEIPIYSKEPNSASSTHQMHVSLKEDENNSNITRLF Sbjct: 241 FNDFIKRLKTGKCSAFPDVPDKENFEIPIYSKEPNSASSTHQMHVSLKEDENNSNITRLF 300 Query: 275 REKDDGMNFTQCHTANIQTLIPTSSETNSRESKGNDITIYGNDFMDLTFNHTLQILPATG 334 REKDDGMNFTQCHTANIQTLIPTSSETNSRESKGNDITIYGNDFMDLTFNHTLQILPATG Sbjct: 301 REKDDGMNFTQCHTANIQTLIPTSSETNSRESKGNDITIYGNDFMDLTFNHTLQILPATG 360 Query: 335 NFSEIENQTQNAMDVTTGYGTKASGNKTVFKSKQNTAFQDLSINSADKIHITRSHIMGAE 394 NFSEIENQTQNAMDVTTGYGTKASGNKTVFKSKQNTAFQDLSINSADKIHITRSHIMGAE Sbjct: 361 NFSEIENQTQNAMDVTTGYGTKASGNKTVFKSKQNTAFQDLSINSADKIHITRSHIMGAE 420 Query: 395 THIVSQTCNQDARILAMTPESIYSNPSIQGCKTVFYSSCNDAMEMTKCLSNMREEKNLLK 454 THIVSQTCNQDARILAMTPESIYSNPSIQGCKTVFYSSCNDAMEMTKCLSNMREEKNLLK Sbjct: 421 THIVSQTCNQDARILAMTPESIYSNPSIQGCKTVFYSSCNDAMEMTKCLSNMREEKNLLK 480 Query: 455 HDSNYAKMYCNPDAMSSLTEKTIYSGEENMDITKSHTVAIDNQIFKQDQSNVQIAAAPTP 514 HDSNYAKMYCNPDAMSSLTEKTIYSGEENMDITKSHTVAIDNQIFKQDQSNVQIAAAPTP Sbjct: 481 HDSNYAKMYCNPDAMSSLTEKTIYSGEENMDITKSHTVAIDNQIFKQDQSNVQIAAAPTP 540 Query: 515 EKEMMLQNLMTTSEDGKMNVNCNSVPHVSKERIQQSLSNPLSISLTDRKTELLSGENMDL 574 EKEMMLQNLMTTSEDGKMNVNCNSVPHVSKERIQQSLSNPLSISLTDRKTELLSGENMDL Sbjct: 541 EKEMMLQNLMTTSEDGKMNVNCNSVPHVSKERIQQSLSNPLSISLTDRKTELLSGENMDL 600 Query: 575 TESHTSNLGSQVPLAAYNLAPESTSESHSQSKSSSDECEEITKSRNEPFQRSDIIAKNSL 634 TESHTSNLGSQVPLAAYNLAPESTSESHSQSKSSSDECEEITKSRNEPFQRSDIIAKNSL Sbjct: 601 TESHTSNLGSQVPLAAYNLAPESTSESHSQSKSSSDECEEITKSRNEPFQRSDIIAKNSL 660 Query: 635 TDTWNKDKDWVLKILPYLDKDSPQSADCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQS 694 TDTWNKDKDWVLKILPYLDKDSPQSADCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQS Sbjct: 661 TDTWNKDKDWVLKILPYLDKDSPQSADCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQS 720 Query: 695 LFSTTKPLFSSGQFSMKNHDTAISSHTVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMII 754 LFSTTKPLFSSGQFSMKNHDTAISSHTVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMII Sbjct: 721 LFSTTKPLFSSGQFSMKNHDTAISSHTVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMII 780 Query: 755 CSEEEQNMDLTKSHTVVIGFGPSELQELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIE 814 CSEEEQNMDLTKSHTVVIGFGPSELQELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIE Sbjct: 781 CSEEEQNMDLTKSHTVVIGFGPSELQELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIE 840 Query: 815 KSGVLKSNCIMDVLEDESVQKPKFPKEKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDI 874 KSGVLKSNCIMDVLEDESVQKPKFPKEKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDI Sbjct: 841 KSGVLKSNCIMDVLEDESVQKPKFPKEKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDI 900 Query: 875 TKSYTIEINHRPLLEKRDCHLVPLAGTSETILYTCGQDDMEITRSHTTALECKTVSPDEI 934 TKSYTIEINHRPLLEKRDCHLVPLAGTSETILYTCGQDDMEITRSHTTALECKTVSPDEI Sbjct: 901 TKSYTIEINHRPLLEKRDCHLVPLAGTSETILYTCGQDDMEITRSHTTALECKTVSPDEI 960 Query: 935 TTRPMDKTVVFVDNHVELEMTESHTVFIDYQEKERTDRPNFELSQRKSLGTPTVICTPTE 994 TTRPMDKTVVFVDNHVELEMTESHTVFIDYQEKERTDRPNFELSQRKSLGTPTVICTPTE Sbjct: 961 TTRPMDKTVVFVDNHVELEMTESHTVFIDYQEKERTDRPNFELSQRKSLGTPTVICTPTE 1020 Query: 995 ESVFFPGNGESDRLVANDSQLTPLEEWSNNRGPVEVADNMELSKSATCKNIKDVQSPGFL 1054 ESVFFPGNGESDRLVANDSQLTPLEEWSNNRGPVEVADNMELSKSATCKNIKDVQSPGFL Sbjct: 1021 ESVFFPGNGESDRLVANDSQLTPLEEWSNNRGPVEVADNMELSKSATCKNIKDVQSPGFL 1080 Query: 1055 NEPLSSKSQRRKSLKLKNDKTIVFSENHKNDMDITQSCMVEIDNESALEDKEDFHLAGAS 1114 NEPLSSKSQRRKSLKLKNDKTIVFSENHKNDMDITQSCMVEIDNESALEDKEDFHLAGAS Sbjct: 1081 NEPLSSKSQRRKSLKLKNDKTIVFSENHKNDMDITQSCMVEIDNESALEDKEDFHLAGAS 1140 Query: 1115 KTILYSCGQDDMEITRSHTTALECKTLLPNEIAIRPMDKTVLFTDNYSDLEVTDSHTVFI 1174 KTILYSCGQDDMEITRSHTTALECKTLLPNEIAIRPMDKTVLFTDNYSDLEVTDSHTVFI Sbjct: 1141 KTILYSCGQDDMEITRSHTTALECKTLLPNEIAIRPMDKTVLFTDNYSDLEVTDSHTVFI 1200 Query: 1175 DCQATEKILEENPKFGIGKGKNLGVSFPKDNSCVQEIAEKQALAVGNKIVLHTEQKQQLF 1234 DCQATEKILEENPKFGIGKGKNLGVSFPKDNSCVQEIAEKQALAVGNKIVLHTEQKQQLF Sbjct: 1201 DCQATEKILEENPKFGIGKGKNLGVSFPKDNSCVQEIAEKQALAVGNKIVLHTEQKQQLF 1260 Query: 1235 AATNRTTNEIIKFHSAAMDEKVIGKVVDQACTLEKAQVESCQLNNRDRRNVDFTSSHATA 1294 AATNRTTNEIIKFHSAAMDEKVIGKVVDQACTLEKAQVESCQLNNRDRRNVDFTSSHATA Sbjct: 1261 AATNRTTNEIIKFHSAAMDEKVIGKVVDQACTLEKAQVESCQLNNRDRRNVDFTSSHATA 1320 Query: 1295 VCGSSDNYSCLPNVISCTDNLEGSAMLLCDKDEEKANYCPVQNDLAYANDFASEYYLESE 1354 VCGSSDNYSCLPNVISCTDNLEGSAMLLCDKDEEKANYCPVQNDLAYANDFASEYYLESE Sbjct: 1321 VCGSSDNYSCLPNVISCTDNLEGSAMLLCDKDEEKANYCPVQNDLAYANDFASEYYLESE 1380 Query: 1355 GQPLSAPCPLLEKEEVIQTSTKGQLDCVITLHKDQDLIKDPRNLLANQTLVYSQDLGEMT 1414 GQPLSAPCPLLEKEEVIQTSTKGQLDCVITLHKDQDLIKDPRNLLANQTLVYSQDLGEMT Sbjct: 1381 GQPLSAPCPLLEKEEVIQTSTKGQLDCVITLHKDQDLIKDPRNLLANQTLVYSQDLGEMT 1440 Query: 1415 KLNSKRVSFKLPKDQMKVYVDDIYVIPQPHFSTDQPPLPKKGQSSINKEEVILSKAGNKS 1474 KLNSKRVSFKLPKDQMKVYVDDIYVIPQPHFSTDQPPLPKKGQSSINKEEVILSKAGNKS Sbjct: 1441 KLNSKRVSFKLPKDQMKVYVDDIYVIPQPHFSTDQPPLPKKGQSSINKEEVILSKAGNKS 1500 Query: 1475 LNIIENSSAPICENKPKILNSEEWFAAACKKELKENIQTTNYNTALDFHSNSDVTKQVIQ 1534 LNIIENSSAPICENKPKILNSEEWFAAACKKELKENIQTTNYNTALDFHSNSDVTKQVIQ Sbjct: 1501 LNIIENSSAPICENKPKILNSEEWFAAACKKELKENIQTTNYNTALDFHSNSDVTKQVIQ 1560 Query: 1535 THVNAGEAPDPVITSNVPCFHSIKPNLNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAH 1594 THVNAGEAPDPVITSNVPCFHSIKPNLNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAH Sbjct: 1561 THVNAGEAPDPVITSNVPCFHSIKPNLNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAH 1620 Query: 1595 NDMHIVQATEIHNINIISSNAKDSRDEENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFL 1654 NDMHIVQATEIHNINIISSNAKDSRDEENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFL Sbjct: 1621 NDMHIVQATEIHNINIISSNAKDSRDEENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFL 1680 Query: 1655 PRLPNKRNCSVTGIDDLEQIPADTTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYINEE 1714 PRLPNKRNCSVTGIDDLEQIPADTTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYINEE Sbjct: 1681 PRLPNKRNCSVTGIDDLEQIPADTTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYINEE 1740 Query: 1715 NLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKE 1774 NLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKE Sbjct: 1741 NLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKE 1800 Query: 1775 KKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTS 1834 KKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTS Sbjct: 1801 KKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTS 1860 Query: 1835 LDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGN 1894 LDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGN Sbjct: 1861 LDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGN 1920 Query: 1895 FTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWE 1954 FTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWE Sbjct: 1921 FTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWE 1980 Query: 1955 KMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDE 2014 KMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDE Sbjct: 1981 KMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDE 2040 Query: 2015 MDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLL 2074 MDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLL Sbjct: 2041 MDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLL 2100 Query: 2075 ELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITF 2134 ELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITF Sbjct: 2101 ELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITF 2160 Query: 2135 EESVVGFPFLDKRYRKIVDVNFQSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQH 2194 EESVVGFPFLDKRYRKIVDVNFQSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQH Sbjct: 2161 EESVVGFPFLDKRYRKIVDVNFQSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQH 2220 Query: 2195 QLPKMLEEFSLVVHHCRLLGEEIEYLKRWGPNYNLMNIDINNNELRLLFSSSAAFAKFEI 2254 QLPKMLEEFSLVVHHCRLLGEEIEYLKRWGPNYNLMNIDINNNELRLLFSSSAAFAKFEI Sbjct: 2221 QLPKMLEEFSLVVHHCRLLGEEIEYLKRWGPNYNLMNIDINNNELRLLFSSSAAFAKFEI 2280 Query: 2255 TLFLSAYYPSVPLPSTIQNHVGNTSQDDIATILSKVPLENNYLKNVVKQIYQDLFQDCHF 2314 TLFLSAYYPSVPLPSTIQNHVGNTSQDDIATILSKVPLENNYLKNVVKQIYQDLFQDCHF Sbjct: 2281 TLFLSAYYPSVPLPSTIQNHVGNTSQDDIATILSKVPLENNYLKNVVKQIYQDLFQDCHF 2340 Query: 2315 YH 2316 YH Sbjct: 2341 YH 2342 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 55.5 bits (132), Expect = 6e-07 Identities = 92/466 (19%), Positives = 198/466 (42%), Gaps = 64/466 (13%) Query: 1705 LSPSQYINEENLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTW 1764 LS +Q E + + +I +EE+ + + Q+E+S + ++ Sbjct: 420 LSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERI--SLQQELSRVKQEVVDVMKKSSEEQ 477 Query: 1765 VQEEEDIHKEKKIRKN-EIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSS 1823 + + + +H+++ RK E+ T++RE F + ++KS + L K S Sbjct: 478 IAKLQKLHEKELARKEQELTKKLQTRERE-FQEQMKVALEKSQSEYL-KISQEKEQQESL 535 Query: 1824 SLDSIKADGTSL---DFSTYRSSQMESQFLRDTICE--ESLREKLQDGRITIREFFILLQ 1878 +L+ ++ ++ + R Q E++ R I E SL + LQ+ + ++ + L+ Sbjct: 536 ALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLE 595 Query: 1879 ---------VHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQ 1929 + ++++K ++ L E L + + Y+ +++ RE CE ++ Sbjct: 596 AEKNKHNKEITVMVEK-HKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKE 654 Query: 1930 KI--------------------EELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGI 1969 + E+L + + + L ++++ L K RH ++EL Sbjct: 655 TLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVL--KARHKLEEELSVLKD 712 Query: 1970 YLNKIKSCF-TKMTKVFTH--QGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCL 2026 +K+K KM + H Q ++ + S Q + L+ +I++++ +LK+ D L Sbjct: 713 QTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHL 772 Query: 2027 TEMETETKNLEDEEKNNPVEEWDSEMRAAEKEL-----------EQLKTEEEEL---QRN 2072 E + +NLE + K + + E++ A +L EQ K EE+L Q+ Sbjct: 773 KEHQAHVENLEADIKRS-----EGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQK 827 Query: 2073 LLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQ 2118 LL+LE ++ Q+ ++ Q+ LD + D+++ + Q Sbjct: 828 LLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQ 873 Score = 47.0 bits (110), Expect = 2e-04 Identities = 75/397 (18%), Positives = 170/397 (42%), Gaps = 53/397 (13%) Query: 1736 KALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHK-------EKKIRKNEIKFSD-- 1786 + L + YQ E+ K+ + C +K T ++++E I + EK + K ++K ++ Sbjct: 632 QVLKQQYQTEME----KLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELE 687 Query: 1787 --TTQDREIFD--HHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRS 1842 +++ E+ H EE++ SVL + + +D K S + Sbjct: 688 SLSSELSEVLKARHKLEEEL-----SVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKE 742 Query: 1843 SQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPT 1902 ++ Q E++L++++ + ++E H+ + NL + + Sbjct: 743 HEVSIQRT-----EKALKDQINQLELLLKE----RDKHLKEHQAHVENLEADIKRSEGEL 793 Query: 1903 PE-----DLMLS-QYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKM 1956 + D+ S Q + + Y E +QK+ +L+ K + ++ +K Sbjct: 794 QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEA---QKK 850 Query: 1957 RHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGK--VALYGKLVQSAQNEREKL-QIKID 2013 C+ EL A I + + K + K +Y ++ E+E+ QI ++ Sbjct: 851 DVCT--ELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVE 908 Query: 2014 EMDKILKKIDNCLTEMETETKNLEDEEKNNPV--EEWDSEMRAAEKELEQLKTEEEELQR 2071 + + IL+ + E+E T+ L +E + + EE++++ + EK++E++K + +E+Q Sbjct: 909 KENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQE 968 Query: 2072 NL------LELEVQKEQTLAQIDFMQKQRNRTEELLD 2102 L E +++KE ++ QK++ ++L+ Sbjct: 969 TLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLE 1005 Score = 43.1 bits (100), Expect = 0.003 Identities = 82/419 (19%), Positives = 171/419 (40%), Gaps = 79/419 (18%) Query: 1713 EENLPVYPDEINSSDSINIETEEKALIETYQKEI--SPYENKMGKTCNSQKRTWVQEEED 1770 E+ L +E+ I ++ +E+ + E QK + + +M K K V+++ Sbjct: 1048 EKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTT 1107 Query: 1771 IHK-EKKIRKNEIKFSDTTQDREIFDHHTEE---DIDKSANS--------VLIKNLSRTP 1818 +++ ++++++ + QD H E+ D++KS V +K L+ Sbjct: 1108 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEED 1167 Query: 1819 SSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQ 1878 S L S K T +F + +SS +S +SL +K + + E + +Q Sbjct: 1168 KRKVSELTS-KLKTTDEEFQSLKSSHEKSN--------KSLEDKSLEFKKLSEE--LAIQ 1216 Query: 1879 VHILIQKPRQS-NLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLS 1937 + I +K N +N + + +LS+ + C+ R K++E L Sbjct: 1217 LDICCKKTEALLEAKTNELINISSSKTNAILSRISH----------CQHRTTKVKEALL- 1265 Query: 1938 ASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQ-----GKVA 1992 ++ C+ EL+A L + ++ + THQ ++ Sbjct: 1266 ------------------IKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIK 1307 Query: 1993 LYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEM 2052 ++S E+E LQ + + + ++C+T+++ E + E + + Sbjct: 1308 SMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE------------LSENINAV 1355 Query: 2053 RAAEKELEQLKTEEEELQRNLLELEVQKEQTL------AQIDFMQKQRNRTE-ELLDQL 2104 ++EL++ K E L + L +L VQ + ++ A I ++KQ + + ELLDQ+ Sbjct: 1356 TLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQV 1414 Score = 38.9 bits (89), Expect = 0.059 Identities = 105/530 (19%), Positives = 209/530 (39%), Gaps = 106/530 (20%) Query: 1691 SKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSI---NIETEEKALIETYQKEIS 1747 + +GI +L + + I E V+ E+N SI + + + L E ++ ++ Sbjct: 1009 ANSAGISDAVSRLETNQKEQI-ESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQ 1067 Query: 1748 PYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSAN 1807 E ++ + + + E+E+++KE K E DTT + E+ KSA+ Sbjct: 1068 EKEQEVAEL-KQKILLFGCEKEEMNKEITWLKEEGVKQDTT-----LNELQEQLKQKSAH 1121 Query: 1808 SVLIKNLSRTPSSCSSSLDSIKAD-GTSLDFSTYRSSQMESQFLRDTICEESLREKLQDG 1866 + +L++ + + L+ ++ D SL +T+ Q+ + + + E Sbjct: 1122 ---VNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKL 1178 Query: 1867 RITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEA 1926 + T EF L H +SN + ED L ++ I + C Sbjct: 1179 KTTDEEFQSLKSSH------EKSN----------KSLEDKSLEFKKLSEELAIQLDICCK 1222 Query: 1927 RRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFT 1986 + + + E K + L++I+ + + L++I C + TKV Sbjct: 1223 KTEALLEAKTNE------LINISSSKTNAI--------------LSRISHCQHRTTKV-- 1260 Query: 1987 HQGKVALYGKLVQSAQNEREKLQIK---IDEMDKILKKIDNCLTEMETETKNLEDEEKNN 2043 +E L IK + E++ L++ LTE E T N+ ++ + Sbjct: 1261 ------------------KEALLIKTCTVSELEAQLRQ----LTE-EQNTLNISFQQATH 1297 Query: 2044 PVEEWDSEMRAAEKELEQLKTEEEELQR---NLLELEVQKEQTLAQIDFMQKQRNRTEEL 2100 +EE ++++++ + ++E L TE+E LQ+ N + +KE + Q+ + E Sbjct: 1298 QLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQL------KKELSEN 1351 Query: 2101 LDQLSLSEWDV----VEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNF 2156 ++ ++L + ++ VE S T + +Q +I+ E L K+Y D Sbjct: 1352 INAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQY----DEEK 1407 Query: 2157 QSLLDE--------DQAPPSSLLVHKLIFQYVEEKESWKKTCT---TQHQ 2195 LLD+ D + + + + + WKK TQHQ Sbjct: 1408 CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQ 1457 Score = 37.4 bits (85), Expect = 0.17 Identities = 51/216 (23%), Positives = 98/216 (45%), Gaps = 27/216 (12%) Query: 1904 EDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKE 1963 +DL + + ++ +++I +++ + R+ E++K Q+ L + N L + MR + + Sbjct: 1951 KDLRMLRKEHQQELEILKKEYDQERE--EKIK---QEQEDLELKHNSTLKQLMREFNTQL 2005 Query: 1964 LKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKID 2023 + IK K +V +L++S Q E +L KI E D LK+ Sbjct: 2006 AQKEQELEMTIKETINKAQEV---------EAELLESHQEETNQLLKKIAEKDDDLKR-- 2054 Query: 2024 NCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRN----LLELEVQ 2079 + E + +EE V + +++ +K+ +Q K E+EE N ++EL+ Q Sbjct: 2055 --TAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQ-KLEQEENPGNDNVTIMELQTQ 2111 Query: 2080 KEQ--TLAQIDFMQKQ--RNRTEELLDQLSLSEWDV 2111 Q TL +++Q R + L D+L E +V Sbjct: 2112 LAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNV 2147 Score = 36.6 bits (83), Expect = 0.29 Identities = 102/567 (17%), Positives = 207/567 (36%), Gaps = 73/567 (12%) Query: 1668 IDDLEQIPADTTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSD 1727 I+++ + + D+ E + +SS+ S + KL EE L V D+ +D Sbjct: 668 IEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKL---------EEELSVLKDQ---TD 715 Query: 1728 SINIETEEK-------------ALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKE 1774 + E E K ++I+ ++ I E + N Q ++E + KE Sbjct: 716 KMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN-QLELLLKERDKHLKE 774 Query: 1775 KKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTS 1834 + ++ + E+ + D+ +S S + + + T Sbjct: 775 HQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETE 834 Query: 1835 LDFSTYRSSQMESQFLRDTICEESLREKLQ--------DGRITIREFFILLQVHILIQKP 1886 T + +++E+Q + +C E K+Q + + + E + + K Sbjct: 835 RILLTKQVAEVEAQ--KKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKL 892 Query: 1887 RQSNLPGNFTVNTPPTPEDLMLSQYVYRPK-IQIYREDCEARRQKI----EELKLSASNQ 1941 N T E+++L + K I+I + A+ I EE + NQ Sbjct: 893 EDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQ 952 Query: 1942 DKLLVDINKNLWEKMRHCSDK----------ELKAFGIYLNKIKSCFTKMTKVFTHQGKV 1991 +K + + + E K EL+ + L++ + F Sbjct: 953 EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSA 1012 Query: 1992 ALYGKLVQSAQNEREKLQI-------KIDEMDKILKKIDNCLTEMETETKNLEDEEKNNP 2044 + + + N++E+++ +++++ I +K N E E ++ +EK Sbjct: 1013 GISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQE 1072 Query: 2045 VEE-------WDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRT 2097 V E + E KE+ LK E + L EL+ Q +Q A ++ + + + Sbjct: 1073 VAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKL 1132 Query: 2098 EELLDQLSLSEWDVVEWSDDQAVFTFVYD-TIQLTITFEESVVGFPFLDKRYRKIVDVNF 2156 + L++L V+ + TF+ + ++L + EE L + K D F Sbjct: 1133 KAHLEKLE------VDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKL-KTTDEEF 1185 Query: 2157 QSLLDEDQAPPSSLLVHKLIFQYVEEK 2183 QSL + SL L F+ + E+ Sbjct: 1186 QSLKSSHEKSNKSLEDKSLEFKKLSEE 1212 Score = 34.7 bits (78), Expect = 1.1 Identities = 49/222 (22%), Positives = 86/222 (38%), Gaps = 16/222 (7%) Query: 1999 QSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKE 2058 + A + E++ + +E+D+ K+ D EME + +E +E N E R E E Sbjct: 1472 KEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELE 1531 Query: 2059 --LEQLKTEEEELQRNLLELEVQKE-------QTLAQIDFMQKQR-NRTEELLDQLSLSE 2108 + Q E E L L QK+ Q L + +++ NR +E +++ E Sbjct: 1532 DHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLE 1591 Query: 2109 WDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNFQSLLDEDQAPPS 2168 V + + + L++ +E + L+ R L + +A Sbjct: 1592 NQVYSMKAELETKKKELEHVNLSVKSKEEEL--KALEDRLESESAAKLAEL--KRKAEQK 1647 Query: 2169 SLLVHKLIFQYVEEKESWKKTCTTQH--QLPKMLEEFSLVVH 2208 + K + +EEKE K T H +L L+E VH Sbjct: 1648 IAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVH 1689 Score = 34.7 bits (78), Expect = 1.1 Identities = 38/181 (20%), Positives = 81/181 (44%), Gaps = 36/181 (19%) Query: 1940 NQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQ 1999 N + + D+ K L EK C E K + ++ SC + +V Sbjct: 1830 NLENVFDDVQKTLQEKELTCQILEQK-----IKELDSCLVRQKEVH-------------- 1870 Query: 2000 SAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVE------------E 2047 + E E+L K +++ + L+++D E +N E++ K++ V+ + Sbjct: 1871 --RVEMEELTSKYEKL-QALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHND 1927 Query: 2048 WDSEMRAAEKELEQLKTEEEELQRNL--LELEVQKEQTLAQIDFMQKQRNRTEELLDQLS 2105 + ++ AE+E ++L E LQ++L L E Q+E + + ++ Q++ + ++ + L Sbjct: 1928 LEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLE 1987 Query: 2106 L 2106 L Sbjct: 1988 L 1988 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 54.3 bits (129), Expect = 1e-06 Identities = 89/411 (21%), Positives = 170/411 (41%), Gaps = 39/411 (9%) Query: 1721 DEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHK-EKKIRK 1779 ++I I TE E E++ + K+ C+ K+ E + K EK+ Sbjct: 914 NKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 973 Query: 1780 NEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFST 1839 E K + T++ D E I K L K + +LD ++A+ ++ T Sbjct: 974 TENKVKNLTEEMAGLD----ETIAK-----LSKEKKALQETHQQTLDDLQAEEDKVNILT 1024 Query: 1840 YRSSQMESQF--LRDTICEES-LREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFT 1896 +++E Q L ++ +E LR L+ + + L Q + + + L Sbjct: 1025 KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLE 1084 Query: 1897 V------NTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINK 1950 N ED + + KI+ + E ++IE + S + +K D+++ Sbjct: 1085 KKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSR 1144 Query: 1951 NLWEKMRHCSDKELKAFG-----IYLNKIKSC-FTKMTK-----VFTHQGKVALYGKLVQ 1999 L E S++ +A G + LNK + F K+ + H+ VA K Sbjct: 1145 ELEE----ISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200 Query: 2000 SAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLED--EEKNNPVEEWDSEMRAAEK 2057 + E L +ID + ++ +K++ +E++ ET +L E + + R+ E Sbjct: 1201 DSMAE---LGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLED 1257 Query: 2058 ELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSE 2108 ++ +LKT+EEE QR + +L Q+ + + +Q + + L+ QLS S+ Sbjct: 1258 QVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSK 1308 Score = 38.9 bits (89), Expect = 0.059 Identities = 76/417 (18%), Positives = 171/417 (41%), Gaps = 46/417 (11%) Query: 1729 INIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTT 1788 + +ET++ + + + IS + + K C S + V E + +E++ N++ Sbjct: 1227 LKMETDD---LSSNAEAISKAKGNLEKMCRSLEDQ-VSELKTKEEEQQRLINDLTAQRAR 1282 Query: 1789 QDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIK------ADGTSLDFSTYRS 1842 E ++ + D +K A L+ LSR+ + + ++ +K + +S Sbjct: 1283 LQTEAGEYSRQLD-EKDA---LVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQS 1338 Query: 1843 SQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPT 1902 S+ + LR+ EE Q+G+ ++ + + + + + Sbjct: 1339 SRHDCDLLREQYEEE------QEGKAELQRALSKANSEVAQWRTK-------YETDAIQR 1385 Query: 1903 PEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCS-- 1960 E+L ++ ++Q E EA K L+ + + D+ ++ C+ Sbjct: 1386 TEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAAL 1445 Query: 1961 DKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILK 2020 DK+ + F L++ K + + ++++Q E L ++ ++ + + Sbjct: 1446 DKKQRNFDKVLSEWKQKYEETQAE-------------LEASQKESRSLSTELFKVKNVYE 1492 Query: 2021 KIDNCLTEMETETKNLEDE--EKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEV 2078 + + L + E KNL+ E + + E ++ EK +Q++ E+ E+Q L E E Sbjct: 1493 ESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEA 1552 Query: 2079 QKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFE 2135 E +I +Q + N+ + +D+ ++E D E + T V +T+Q T+ E Sbjct: 1553 SLEHEEGKILRIQLELNQVKSEVDR-KIAEKD-EEIDQLKRNHTRVVETMQSTLDAE 1607 Score = 37.0 bits (84), Expect = 0.23 Identities = 34/149 (22%), Positives = 70/149 (46%), Gaps = 13/149 (8%) Query: 1996 KLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDE--EKNNPVEEWDSEMR 2053 K+ +S +++ +L+ K +E +++ + ++TE + EK+ V + + Sbjct: 1250 KMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQ 1309 Query: 2054 AAEKELEQLK--TEEEELQRNLLELEVQKEQ---TLAQIDFMQKQRNRTEELLDQLSLSE 2108 A+ +++E+LK EEE +N L +Q + L + + ++Q + EL LS + Sbjct: 1310 ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKA-ELQRALSKAN 1368 Query: 2109 WDVVEWSDDQAVFTFVYDTIQLTITFEES 2137 +V +W + D IQ T EE+ Sbjct: 1369 SEVAQWRT-----KYETDAIQRTEELEEA 1392 Score = 36.2 bits (82), Expect = 0.39 Identities = 43/219 (19%), Positives = 99/219 (45%), Gaps = 26/219 (11%) Query: 1918 QIYREDCEARRQKIEELKLSASNQDKLLVDINKNLW------EKMRHCSDKELKAFGIYL 1971 Q++ +D ++ ++E + LL + LW E+ R +++EL Sbjct: 1657 QLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDAS--- 1713 Query: 1972 NKIKSCFTKMTKVFTHQGKV--------ALYGKLVQSAQNEREKLQIKIDE---MDKILK 2020 +++ T+ T + + K+ + +++Q ++N EK + I + M + LK Sbjct: 1714 ERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELK 1773 Query: 2021 KIDNCLTEMETETKNLEDEEKN--NPVEEWDS-EMRAAEKELEQLKTEEEELQRNLLELE 2077 K + +E KNLE K+ + ++E + ++ +K++++L+ EL+ E+E Sbjct: 1774 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEG---EVE 1830 Query: 2078 VQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSD 2116 ++++ + ++K R +EL Q +V+ D Sbjct: 1831 NEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQD 1869 >gi|118498362 kinectin 1 isoform b [Homo sapiens] Length = 1306 Score = 53.9 bits (128), Expect = 2e-06 Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 6/129 (4%) Query: 1996 KLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAA 2055 KL +S + E K ++K+DE K +K++ + T E E + L E K+ +E E Sbjct: 1129 KLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKD--IENLRREREHL 1186 Query: 2056 EKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRT----EELLDQLSLSEWDV 2111 E ELE+ + E + EL+ Q +TL ++ Q +R + + L L + + Sbjct: 1187 EMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1246 Query: 2112 VEWSDDQAV 2120 V+ + D V Sbjct: 1247 VKAAGDTTV 1255 Score = 37.0 bits (84), Expect = 0.23 Identities = 50/335 (14%), Positives = 150/335 (44%), Gaps = 30/335 (8%) Query: 1912 VYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYL 1971 V++ KI + ++ + + K ++++ + L N L + + + +++ L Sbjct: 389 VFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAEL 448 Query: 1972 NKIKSCFTKMTKVFTHQ-GKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEME 2030 NK++ + ++ T + GK+ ++A+ +L++++ E ++ +++ + + + Sbjct: 449 NKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRT 508 Query: 2031 TETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFM 2090 E + + + ++ V + ++E+++ +L +++L++ L++L +++ + + + + Sbjct: 509 AEHEAAQQDLQSKFVAK-ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESL 567 Query: 2091 QKQRNRTEELLDQLSLSEWDVVEWSDDQAVFT-----------FVYDTIQLTITFEESVV 2139 Q Q +++L+Q + + ++ A T + + + E+S+ Sbjct: 568 QMQ---VQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLA 624 Query: 2140 G----FPFLDKRYRKIVDVNF---------QSLLDEDQAPPSSLLVHKLIFQYVEEKESW 2186 ++ + I ++NF Q+L +E QA + L YV++ + Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANE-QAAAAHELEKMQQSVYVKDDKIR 683 Query: 2187 KKTCTTQHQLPKMLEEFSLVVHHCRLLGEEIEYLK 2221 QH++ +EEF ++ + L E++ L+ Sbjct: 684 LLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQ 718 Score = 32.3 bits (72), Expect = 5.6 Identities = 17/103 (16%), Positives = 53/103 (51%), Gaps = 7/103 (6%) Query: 1999 QSAQNEREKLQIKIDEMDK--ILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAE 2056 ++ ++E +KLQ + E ++++++ C+ E + + K +E+ + ++ + E Sbjct: 708 KALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQ-----VATKE 762 Query: 2057 KELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEE 2099 +EL ++TE L + + +L+ ++ ++ +++ + E Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHE 805 >gi|118498368 kinectin 1 isoform c [Homo sapiens] Length = 1300 Score = 53.9 bits (128), Expect = 2e-06 Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 6/129 (4%) Query: 1996 KLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAA 2055 KL +S + E K ++K+DE K +K++ + T E E + L E K+ +E E Sbjct: 1123 KLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKD--IENLRREREHL 1180 Query: 2056 EKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRT----EELLDQLSLSEWDV 2111 E ELE+ + E + EL+ Q +TL ++ Q +R + + L L + + Sbjct: 1181 EMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1240 Query: 2112 VEWSDDQAV 2120 V+ + D V Sbjct: 1241 VKAAGDTTV 1249 Score = 37.0 bits (84), Expect = 0.23 Identities = 50/335 (14%), Positives = 150/335 (44%), Gaps = 30/335 (8%) Query: 1912 VYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYL 1971 V++ KI + ++ + + K ++++ + L N L + + + +++ L Sbjct: 389 VFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAEL 448 Query: 1972 NKIKSCFTKMTKVFTHQ-GKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEME 2030 NK++ + ++ T + GK+ ++A+ +L++++ E ++ +++ + + + Sbjct: 449 NKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRT 508 Query: 2031 TETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFM 2090 E + + + ++ V + ++E+++ +L +++L++ L++L +++ + + + + Sbjct: 509 AEHEAAQQDLQSKFVAK-ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESL 567 Query: 2091 QKQRNRTEELLDQLSLSEWDVVEWSDDQAVFT-----------FVYDTIQLTITFEESVV 2139 Q Q +++L+Q + + ++ A T + + + E+S+ Sbjct: 568 QMQ---VQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLA 624 Query: 2140 G----FPFLDKRYRKIVDVNF---------QSLLDEDQAPPSSLLVHKLIFQYVEEKESW 2186 ++ + I ++NF Q+L +E QA + L YV++ + Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANE-QAAAAHELEKMQQSVYVKDDKIR 683 Query: 2187 KKTCTTQHQLPKMLEEFSLVVHHCRLLGEEIEYLK 2221 QH++ +EEF ++ + L E++ L+ Sbjct: 684 LLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQ 718 Score = 32.3 bits (72), Expect = 5.6 Identities = 17/103 (16%), Positives = 53/103 (51%), Gaps = 7/103 (6%) Query: 1999 QSAQNEREKLQIKIDEMDK--ILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAE 2056 ++ ++E +KLQ + E ++++++ C+ E + + K +E+ + ++ + E Sbjct: 708 KALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQ-----VATKE 762 Query: 2057 KELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEE 2099 +EL ++TE L + + +L+ ++ ++ +++ + E Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHE 805 >gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sapiens] Length = 1843 Score = 52.8 bits (125), Expect = 4e-06 Identities = 90/424 (21%), Positives = 187/424 (44%), Gaps = 62/424 (14%) Query: 1704 NLSPSQYINEENLPVYPDEINSSDSINIETEEKAL---IETYQKEISPYENKMGKTCNSQ 1760 N S ++ + E V E N+S + +E E + L +E + EI + + + C + Sbjct: 469 NQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSL-QNCQNL 527 Query: 1761 KRTWVQEEEDIHKE-KKIRKN---EIKF------------SDTTQDREIFDHHTEEDIDK 1804 + ++E+ + K + +R+N +IK S Q +I +DI+K Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK 587 Query: 1805 SANSVLIKNLSRTPSSCSS---SLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLRE 1861 N +L +++ T S S IK + R+ ++E++ E L++ Sbjct: 588 E-NKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQK 646 Query: 1862 KLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLS-QYVYRPKIQIY 1920 K+ + +IT + L Q + +++ + T + ++L + + + Q+ Sbjct: 647 KITNLKITCEKIEALEQENSELERENRK------LKKTLDSFKNLTFQLESLEKENSQLD 700 Query: 1921 REDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTK 1980 E+ E RR +E LK ++ +L ++ NK L S+KE G+ L +K+ F K Sbjct: 701 EENLELRRN-VESLKCASMKMAQLQLE-NKELE------SEKEQLKKGLEL--LKASFKK 750 Query: 1981 MTKV-FTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDE 2039 ++ ++QG L I+ + K L+ + + ++E+E ++LE E Sbjct: 751 TERLEVSYQG------------------LDIENQRLQKTLENSNKKIQQLESELQDLEME 792 Query: 2040 EKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEE 2099 N +++ E++ + K LEQL+ E + L++ +LE K+Q + +++Q + Sbjct: 793 --NQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850 Query: 2100 LLDQ 2103 L++ Sbjct: 851 TLEE 854 Score = 45.4 bits (106), Expect = 6e-04 Identities = 74/414 (17%), Positives = 170/414 (41%), Gaps = 58/414 (14%) Query: 1711 INEENLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEE- 1769 ++EENL + + +S+ + + A ++ KE+ + ++ K K ++ + E Sbjct: 699 LDEENLELR----RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 754 Query: 1770 -------DIHKE----------KKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIK 1812 DI + KKI++ E + D + + + EE +S ++ Sbjct: 755 EVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEE---LKISSKRLE 811 Query: 1813 NLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEES---LREKLQDGRIT 1869 L + S ++ D L+ R Q ++DT EE+ + ++ + Sbjct: 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE--IKDTTLEENNVKIGNLEKENKTL 869 Query: 1870 IREFFILLQVHILIQKPRQSNLP----GNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCE 1925 +E I + + +++ + N + T T + ++S+ + K Q D E Sbjct: 870 SKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL---KTQQMNNDLE 926 Query: 1926 ARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVF 1985 ++E++ L N+++LL D D K + +K++S K ++ Sbjct: 927 KLTHELEKIGL---NKERLLHDEQST--------DDSRYK---LLESKLESTLKKSLEI- 971 Query: 1986 THQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEK-NNP 2044 + K+A ++ + N ++L+ ++ K +KK L + + E + ++ + Sbjct: 972 -KEEKIAALEARLEESTNYNQQLRQEL----KTVKKNYEALKQRQDEERMVQSSPPISGE 1026 Query: 2045 VEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTE 2098 +W+ E + +EL ++K E++RN L+ +K+ Q+ ++ Q N + Sbjct: 1027 DNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1080 Score = 43.9 bits (102), Expect = 0.002 Identities = 77/400 (19%), Positives = 165/400 (41%), Gaps = 43/400 (10%) Query: 1721 DEINSSDSINIETEEKALIETYQK---EISPYENKMGKTCNSQK-------RTWVQEEED 1770 +E+ SS + +E E ++L +T ++ + E K +K + + E E Sbjct: 455 NELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEI 514 Query: 1771 IHKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKA 1830 + +++ ++ + D +++ + E + S IK L + + ++ S++ Sbjct: 515 VQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQ--IKILEQENEHLNQTVSSLRQ 572 Query: 1831 DGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSN 1890 + + + E++ L ++I E S KL R+ L+ H + R Sbjct: 573 RSQISAEARVKDIEKENKILHESIKETS--SKLSKIEFEKRQIKKELE-HYKEKGERAEE 629 Query: 1891 LPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINK 1950 L E+ +L + + KI E EA Q+ EL+ K L D K Sbjct: 630 LENELH---HLEKENELLQKKITNLKITC--EKIEALEQENSELERENRKLKKTL-DSFK 683 Query: 1951 NLW------EKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNE 2004 NL EK D+E + +K KM ++ ++ ++E Sbjct: 684 NLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKEL----------ESE 733 Query: 2005 REKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKT 2064 +E+L+ ++ + KK + E+ + ++E++ +E + +++ E EL+ L+ Sbjct: 734 KEQLKKGLELLKASFKKTERL--EVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEM 791 Query: 2065 EEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQL 2104 E + LQ+NL EL++ + +++ ++K+ E+ QL Sbjct: 792 ENQTLQKNLEELKISSK----RLEQLEKENKSLEQETSQL 827 Score = 39.3 bits (90), Expect = 0.045 Identities = 190/1027 (18%), Positives = 395/1027 (38%), Gaps = 177/1027 (17%) Query: 117 IHTQMQQKEFSIIEHTRERKHANDQTVIFSDENQMDLTSSHTVMITKGLLDNPISEKSTK 176 + ++++K +++ +E + + EN L+ + + + + LD + EK+ + Sbjct: 263 LRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD-ALREKAVR 321 Query: 177 IDTTSFLANLKLHTEDSRMKKEVNFSVDQNTSSENKIDFNDFIKRLKTGKCSAFPDVPDK 236 +D KL +E SR K+ ++ E + N + KT + Sbjct: 322 VD--------KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR 373 Query: 237 ENFEIPIYSKEPNSASSTHQMH-VSLKEDENNSNITRLFREKDDGMNFTQCHTANIQTLI 295 + ++ E + ++H + ++ D + I L E++ + Q + + + Sbjct: 374 SD---KLHELEKENLQLKAKLHDMEMERDMDRKKIEELM-EENMTLEMAQKQSMDESLHL 429 Query: 296 PTSSETNSRESKGNDIT--IYGNDFMDLTFNHTLQILPATGNFSEIENQTQNAMDVTTGY 353 E SR S+ ++ G++ +LT + L++ E+ENQ Sbjct: 430 GWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKL--------EMENQ----------- 470 Query: 354 GTKASGNKTVFKSKQNTAFQDLSINSADKIHITRSHIMGAETHIVSQTCNQDARILAMTP 413 S KTV + + + D + S I+ E +Q ++ IL Sbjct: 471 ----SLTKTVEELR----------TTVDSVEGNASKILKMEKE--NQRLSKKVEILEN-- 512 Query: 414 ESIYSNPSIQGCKTVFYSSCNDAMEMTKCLSNMREEKN----LLKHDSNYAKMYCNPDAM 469 E + S+Q C+ + + ++ K + +RE +L+ ++ + + Sbjct: 513 EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQ-----TV 567 Query: 470 SSLTEKTIYSGEENM-DITKSHTVAIDNQIFKQDQSNVQIAAAPTPEKEMMLQNLMTTSE 528 SSL +++ S E + DI K + + ++ K+ S + EK + + L E Sbjct: 568 SSLRQRSQISAEARVKDIEKENKIL--HESIKETSSKLSKIEF---EKRQIKKELEHYKE 622 Query: 529 DGKMNVNC-NSVPHVSKER--IQQSLSNPLSISLTDRKTELLSGENMDLTESHTSNLGSQ 585 G+ N + H+ KE +Q+ ++N + +T K E L EN +L + + Sbjct: 623 KGERAEELENELHHLEKENELLQKKITN---LKITCEKIEALEQENSELERENRKLKKTL 679 Query: 586 VPLAAYNLAPESTSESHSQSKSSSDECEEITKS-RNEPFQRSDIIAKNSLTDTWNKDKDW 644 ES + +SQ + E +S + + + + +N ++ + Sbjct: 680 DSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKK 739 Query: 645 VLKILPYLDKDSPQSADCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQSLFSTTKPLFS 704 L++L K + + Q + + L K + N N Q L S + L Sbjct: 740 GLELLKASFKKTERLEVSYQGLDIENQR------LQKTLENSNKKI--QQLESELQDLEM 791 Query: 705 SGQFSMKN-HDTAISSHTVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMIICSEEEQNMD 763 Q KN + ISS ++ + +N KSL T DK + E++N Sbjct: 792 ENQTLQKNLEELKISSKRLEQLEKEN--------KSLEQETSQLEKDKKQL---EKENKR 840 Query: 764 LTKSHTVVIGFGPSELQELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIEKSGVLKSNC 823 L + E+ T LE ++ + EK K+ ++ G+ K +C Sbjct: 841 LRQQ------------AEIKDTTLEENNVKIGNL--------EKENKTLSKEIGIYKESC 880 Query: 824 IMDVLEDESVQKPKFPKEKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDITKSYTIEIN 883 + L++ EK+N ++ R ++ KT+V +D + K T ++N Sbjct: 881 VR--LKE---------LEKENKELVKRATID----IKTLVTLRED---LVSEKLKTQQMN 922 Query: 884 HRPLLEKRDCHLVPLAGTSETILYTCGQDDMEITRSHTTALECKTVSPDEITTRPMDKTV 943 + LEK L + E +L+ D+ S LE K S + + ++ + Sbjct: 923 ND--LEKLTHELEKIGLNKERLLH----DEQSTDDSRYKLLESKLESTLKKSLEIKEEKI 976 Query: 944 VFVDNHVELEMTESHTVFIDYQEKERTDRPNFELSQRKSLGTPTVICTPTEESVFFPGNG 1003 ++ +E ES +++ +T + N+E +++ V +P P +G Sbjct: 977 AALEARLE----ESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSP-------PISG 1025 Query: 1004 ESDRLVANDSQLTPLEEWSNNRGPVEVADN---MELSKSATCKNIKDVQSPGFLNEPLSS 1060 E ++ +SQ T E +EV N ++ K A +K +++ N L + Sbjct: 1026 EDNKW-ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQ---NNNLQA 1081 Query: 1061 K--SQRRKSLKLKNDKTIVFSENHKNDMD------------------ITQSCMVEIDNES 1100 + + +R+++ L+ T + ++N K ++ + Q +E +NES Sbjct: 1082 QILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENES 1141 Query: 1101 ALEDKED 1107 ++++ED Sbjct: 1142 VIKERED 1148 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 52.8 bits (125), Expect = 4e-06 Identities = 90/424 (21%), Positives = 187/424 (44%), Gaps = 62/424 (14%) Query: 1704 NLSPSQYINEENLPVYPDEINSSDSINIETEEKAL---IETYQKEISPYENKMGKTCNSQ 1760 N S ++ + E V E N+S + +E E + L +E + EI + + + C + Sbjct: 469 NQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSL-QNCQNL 527 Query: 1761 KRTWVQEEEDIHKE-KKIRKN---EIKF------------SDTTQDREIFDHHTEEDIDK 1804 + ++E+ + K + +R+N +IK S Q +I +DI+K Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK 587 Query: 1805 SANSVLIKNLSRTPSSCSS---SLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLRE 1861 N +L +++ T S S IK + R+ ++E++ E L++ Sbjct: 588 E-NKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQK 646 Query: 1862 KLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLS-QYVYRPKIQIY 1920 K+ + +IT + L Q + +++ + T + ++L + + + Q+ Sbjct: 647 KITNLKITCEKIEALEQENSELERENRK------LKKTLDSFKNLTFQLESLEKENSQLD 700 Query: 1921 REDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTK 1980 E+ E RR +E LK ++ +L ++ NK L S+KE G+ L +K+ F K Sbjct: 701 EENLELRRN-VESLKCASMKMAQLQLE-NKELE------SEKEQLKKGLEL--LKASFKK 750 Query: 1981 MTKV-FTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDE 2039 ++ ++QG L I+ + K L+ + + ++E+E ++LE E Sbjct: 751 TERLEVSYQG------------------LDIENQRLQKTLENSNKKIQQLESELQDLEME 792 Query: 2040 EKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEE 2099 N +++ E++ + K LEQL+ E + L++ +LE K+Q + +++Q + Sbjct: 793 --NQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850 Query: 2100 LLDQ 2103 L++ Sbjct: 851 TLEE 854 Score = 45.8 bits (107), Expect = 5e-04 Identities = 74/414 (17%), Positives = 171/414 (41%), Gaps = 59/414 (14%) Query: 1711 INEENLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEE- 1769 ++EENL + + +S+ + + A ++ KE+ + ++ K K ++ + E Sbjct: 699 LDEENLELR----RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 754 Query: 1770 -------DIHKE----------KKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIK 1812 DI + KKI++ E + D + + + EE +S ++ Sbjct: 755 EVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEE---LKISSKRLE 811 Query: 1813 NLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEES---LREKLQDGRIT 1869 L + S ++ D L+ R Q ++DT EE+ + ++ + Sbjct: 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE--IKDTTLEENNVKIGNLEKENKTL 869 Query: 1870 IREFFILLQVHILIQKPRQSNLP----GNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCE 1925 +E I + + +++ + N + T T + ++S+ + K Q D E Sbjct: 870 SKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL---KTQQMNNDLE 926 Query: 1926 ARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVF 1985 ++E++ L N+++LL D +D K + +K++S K ++ Sbjct: 927 KLTHELEKIGL---NKERLLHD---------EQSTDDRYK---LLESKLESTLKKSLEI- 970 Query: 1986 THQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEK-NNP 2044 + K+A ++ + N ++L+ ++ K +KK L + + E + ++ + Sbjct: 971 -KEEKIAALEARLEESTNYNQQLRQEL----KTVKKNYEALKQRQDEERMVQSSPPISGE 1025 Query: 2045 VEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTE 2098 +W+ E + +EL ++K E++RN L+ +K+ Q+ ++ Q N + Sbjct: 1026 DNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1079 Score = 43.9 bits (102), Expect = 0.002 Identities = 77/400 (19%), Positives = 165/400 (41%), Gaps = 43/400 (10%) Query: 1721 DEINSSDSINIETEEKALIETYQK---EISPYENKMGKTCNSQK-------RTWVQEEED 1770 +E+ SS + +E E ++L +T ++ + E K +K + + E E Sbjct: 455 NELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEI 514 Query: 1771 IHKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKA 1830 + +++ ++ + D +++ + E + S IK L + + ++ S++ Sbjct: 515 VQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQ--IKILEQENEHLNQTVSSLRQ 572 Query: 1831 DGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSN 1890 + + + E++ L ++I E S KL R+ L+ H + R Sbjct: 573 RSQISAEARVKDIEKENKILHESIKETS--SKLSKIEFEKRQIKKELE-HYKEKGERAEE 629 Query: 1891 LPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINK 1950 L E+ +L + + KI E EA Q+ EL+ K L D K Sbjct: 630 LENELH---HLEKENELLQKKITNLKITC--EKIEALEQENSELERENRKLKKTL-DSFK 683 Query: 1951 NLW------EKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNE 2004 NL EK D+E + +K KM ++ ++ ++E Sbjct: 684 NLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKEL----------ESE 733 Query: 2005 REKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKT 2064 +E+L+ ++ + KK + E+ + ++E++ +E + +++ E EL+ L+ Sbjct: 734 KEQLKKGLELLKASFKKTERL--EVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEM 791 Query: 2065 EEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQL 2104 E + LQ+NL EL++ + +++ ++K+ E+ QL Sbjct: 792 ENQTLQKNLEELKISSK----RLEQLEKENKSLEQETSQL 827 Score = 38.5 bits (88), Expect = 0.078 Identities = 190/1027 (18%), Positives = 395/1027 (38%), Gaps = 178/1027 (17%) Query: 117 IHTQMQQKEFSIIEHTRERKHANDQTVIFSDENQMDLTSSHTVMITKGLLDNPISEKSTK 176 + ++++K +++ +E + + EN L+ + + + + LD + EK+ + Sbjct: 263 LRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD-ALREKAVR 321 Query: 177 IDTTSFLANLKLHTEDSRMKKEVNFSVDQNTSSENKIDFNDFIKRLKTGKCSAFPDVPDK 236 +D KL +E SR K+ ++ E + N + KT + Sbjct: 322 VD--------KLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR 373 Query: 237 ENFEIPIYSKEPNSASSTHQMH-VSLKEDENNSNITRLFREKDDGMNFTQCHTANIQTLI 295 + ++ E + ++H + ++ D + I L E++ + Q + + + Sbjct: 374 SD---KLHELEKENLQLKAKLHDMEMERDMDRKKIEELM-EENMTLEMAQKQSMDESLHL 429 Query: 296 PTSSETNSRESKGNDIT--IYGNDFMDLTFNHTLQILPATGNFSEIENQTQNAMDVTTGY 353 E SR S+ ++ G++ +LT + L++ E+ENQ Sbjct: 430 GWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKL--------EMENQ----------- 470 Query: 354 GTKASGNKTVFKSKQNTAFQDLSINSADKIHITRSHIMGAETHIVSQTCNQDARILAMTP 413 S KTV + + + D + S I+ E +Q ++ IL Sbjct: 471 ----SLTKTVEELR----------TTVDSVEGNASKILKMEKE--NQRLSKKVEILEN-- 512 Query: 414 ESIYSNPSIQGCKTVFYSSCNDAMEMTKCLSNMREEKN----LLKHDSNYAKMYCNPDAM 469 E + S+Q C+ + + ++ K + +RE +L+ ++ + + Sbjct: 513 EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQ-----TV 567 Query: 470 SSLTEKTIYSGEENM-DITKSHTVAIDNQIFKQDQSNVQIAAAPTPEKEMMLQNLMTTSE 528 SSL +++ S E + DI K + + ++ K+ S + EK + + L E Sbjct: 568 SSLRQRSQISAEARVKDIEKENKIL--HESIKETSSKLSKIEF---EKRQIKKELEHYKE 622 Query: 529 DGKMNVNC-NSVPHVSKER--IQQSLSNPLSISLTDRKTELLSGENMDLTESHTSNLGSQ 585 G+ N + H+ KE +Q+ ++N + +T K E L EN +L + + Sbjct: 623 KGERAEELENELHHLEKENELLQKKITN---LKITCEKIEALEQENSELERENRKLKKTL 679 Query: 586 VPLAAYNLAPESTSESHSQSKSSSDECEEITKS-RNEPFQRSDIIAKNSLTDTWNKDKDW 644 ES + +SQ + E +S + + + + +N ++ + Sbjct: 680 DSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKK 739 Query: 645 VLKILPYLDKDSPQSADCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQSLFSTTKPLFS 704 L++L K + + Q + + L K + N N Q L S + L Sbjct: 740 GLELLKASFKKTERLEVSYQGLDIENQR------LQKTLENSNKKI--QQLESELQDLEM 791 Query: 705 SGQFSMKN-HDTAISSHTVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMIICSEEEQNMD 763 Q KN + ISS ++ + +N KSL T DK + E++N Sbjct: 792 ENQTLQKNLEELKISSKRLEQLEKEN--------KSLEQETSQLEKDKKQL---EKENKR 840 Query: 764 LTKSHTVVIGFGPSELQELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIEKSGVLKSNC 823 L + E+ T LE ++ + EK K+ ++ G+ K +C Sbjct: 841 LRQQ------------AEIKDTTLEENNVKIGNL--------EKENKTLSKEIGIYKESC 880 Query: 824 IMDVLEDESVQKPKFPKEKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDITKSYTIEIN 883 + L++ EK+N ++ R ++ KT+V +D + K T ++N Sbjct: 881 VR--LKE---------LEKENKELVKRATID----IKTLVTLRED---LVSEKLKTQQMN 922 Query: 884 HRPLLEKRDCHLVPLAGTSETILYTCGQDDMEITRSHTTALECKTVSPDEITTRPMDKTV 943 + LEK L + E +L+ D + T LE K S + + ++ + Sbjct: 923 ND--LEKLTHELEKIGLNKERLLH-----DEQSTDDRYKLLESKLESTLKKSLEIKEEKI 975 Query: 944 VFVDNHVELEMTESHTVFIDYQEKERTDRPNFELSQRKSLGTPTVICTPTEESVFFPGNG 1003 ++ +E ES +++ +T + N+E +++ V +P P +G Sbjct: 976 AALEARLE----ESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSP-------PISG 1024 Query: 1004 ESDRLVANDSQLTPLEEWSNNRGPVEVADN---MELSKSATCKNIKDVQSPGFLNEPLSS 1060 E ++ +SQ T E +EV N ++ K A +K +++ N L + Sbjct: 1025 EDNKW-ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQ---NNNLQA 1080 Query: 1061 K--SQRRKSLKLKNDKTIVFSENHKNDMD------------------ITQSCMVEIDNES 1100 + + +R+++ L+ T + ++N K ++ + Q +E +NES Sbjct: 1081 QILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENES 1140 Query: 1101 ALEDKED 1107 ++++ED Sbjct: 1141 VIKERED 1147 >gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo sapiens] Length = 1939 Score = 52.0 bits (123), Expect = 7e-06 Identities = 49/205 (23%), Positives = 91/205 (44%), Gaps = 24/205 (11%) Query: 1904 EDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNL---WEKMRHCS 1960 E+ + ++ R K + R D ++I E A +++NK ++KMR Sbjct: 1123 EEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR--- 1179 Query: 1961 DKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILK 2020 ++L+ + + K H VA G+ + S Q ++KL+ E ++ Sbjct: 1180 -RDLEESTLQHEATAAALRKK-----HADSVAELGEQIDSLQRVKQKLE---KEKSELKM 1230 Query: 2021 KIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQK 2080 +I++ + MET +K + EK R E +L ++KT+EEE QR + EL QK Sbjct: 1231 EINDLASNMETVSKAKANFEKM---------CRTLEDQLSEIKTKEEEQQRLINELSAQK 1281 Query: 2081 EQTLAQIDFMQKQRNRTEELLDQLS 2105 + + +Q + + ++ QLS Sbjct: 1282 ARLHTESGEFSRQLDEKDAMVSQLS 1306 Score = 41.2 bits (95), Expect = 0.012 Identities = 70/367 (19%), Positives = 155/367 (42%), Gaps = 47/367 (12%) Query: 1759 SQKRTWVQEEEDI--HKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSR 1816 S+ +T ++E E H+E KI + +++ + + + +E++D+ L +N R Sbjct: 1542 SELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQ-----LKRNHLR 1596 Query: 1817 TPSSCSSSLDS-IKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFI 1875 S S+LD+ I++ +L + ++ E L++ R T Sbjct: 1597 VVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQG---- 1652 Query: 1876 LLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELK 1935 I K Q +L +DL + + + + + E R +E + Sbjct: 1653 -------ILKDTQLHLDDAIRGQ-----DDLKEQLAMVERRANLMQAEVEELRASLERTE 1700 Query: 1936 LSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYG 1995 ++ L+D ++ + ++ H + L +N K T ++++ QG++ Sbjct: 1701 RGRKMAEQELLDASERV--QLLHTQNTSL------INTKKKLETDISQI---QGEME--- 1746 Query: 1996 KLVQSAQNEREKLQIKIDE---MDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSE- 2051 +VQ A+N EK + I + M + LKK + +E KN+E K+ + ++E Sbjct: 1747 DIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQ 1806 Query: 2052 --MRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEW 2109 ++ +K++++L+ EL+ E+E +++ + + ++K R +EL Q Sbjct: 1807 LALKGGKKQIQKLEARVRELES---EVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRK 1863 Query: 2110 DVVEWSD 2116 +++ D Sbjct: 1864 NILRLQD 1870 Score = 37.0 bits (84), Expect = 0.23 Identities = 42/208 (20%), Positives = 92/208 (44%), Gaps = 33/208 (15%) Query: 1926 ARRQKIE----ELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKM 1981 A+++K+E ELK + + L + EK +H ++ ++K + + K+ Sbjct: 942 AKKRKLEDECSELKKDIDDLELTLAKV-----EKEKHATENKVKNLTEEMAGLDETIAKL 996 Query: 1982 TKVF-----THQ---GKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETET 2033 TK HQ + + V + + KL+ ++D+++ L++ ++E Sbjct: 997 TKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAK 1056 Query: 2034 KNLEDEEK---------NNPVEEWDSEMRAAEKELEQL--KTEEEE-----LQRNLLELE 2077 + LE + K N ++ + +++ E E+ L K E+E+ LQ+ + EL+ Sbjct: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQ 1116 Query: 2078 VQKEQTLAQIDFMQKQRNRTEELLDQLS 2105 + E+ +I+ + R + E+ LS Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLS 1144 Score = 37.0 bits (84), Expect = 0.23 Identities = 41/186 (22%), Positives = 81/186 (43%), Gaps = 12/186 (6%) Query: 1922 EDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKM 1981 +D + K+ L + + ++ + D+ +L ++ + C D E +A +K + Sbjct: 1012 DDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLE-RAKRKLEGDLK--LAQE 1068 Query: 1982 TKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEK 2041 + + T K L KL + + E LQ KI++ + ++ + E++ + LE+E Sbjct: 1069 STMDTENDKQQLNEKL-KKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEE-- 1125 Query: 2042 NNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELL 2101 +E + AEK+ L E EE+ LE T AQI+ +K+ +++ Sbjct: 1126 ---IEAERASRAKAEKQRSDLSRELEEISE---RLEEAGGATSAQIEMNKKREAEFQKMR 1179 Query: 2102 DQLSLS 2107 L S Sbjct: 1180 RDLEES 1185 Score = 36.2 bits (82), Expect = 0.39 Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 19/132 (14%) Query: 1998 VQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDE--EKNNPVEEWDSEMRAA 2055 ++++Q E L ++ ++ ++ + L ++ E KNL+ E + + E + Sbjct: 1471 LEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHEL 1530 Query: 2056 EKELEQLKTEEEELQRNLLELEVQKE--------------QTLAQIDFMQKQRNRTEELL 2101 EK +QL E+ ELQ +L E E E Q ++ID +K + EE L Sbjct: 1531 EKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEID--RKIAEKDEE-L 1587 Query: 2102 DQLSLSEWDVVE 2113 DQL + VVE Sbjct: 1588 DQLKRNHLRVVE 1599 Score = 35.0 bits (79), Expect = 0.86 Identities = 34/190 (17%), Positives = 83/190 (43%), Gaps = 17/190 (8%) Query: 1954 EKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKID 2013 ++++ +KE + +N + S ++K A + K+ ++ +++ +++ K + Sbjct: 1215 QRVKQKLEKEKSELKMEINDLASNMETVSKA------KANFEKMCRTLEDQLSEIKTKEE 1268 Query: 2014 EMDKILKKIDNCLTEMETETKNLEDE--EKNNPVEEWDSEMRAAEKELEQLKTEEEELQR 2071 E +++ ++ + TE+ + EK+ V + +A +++E+LK + EE + Sbjct: 1269 EQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETK 1328 Query: 2072 NLLELEVQKEQTLAQIDFMQKQRNRTEELLDQL----SLSEWDVVEWSDDQAVFTFVYDT 2127 L + D +++Q +E +L S + +V +W + D Sbjct: 1329 AKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRT-----KYETDA 1383 Query: 2128 IQLTITFEES 2137 IQ T EE+ Sbjct: 1384 IQRTEELEEA 1393 Score = 33.9 bits (76), Expect = 1.9 Identities = 21/117 (17%), Positives = 56/117 (47%), Gaps = 9/117 (7%) Query: 1998 VQSAQNEREKLQIKIDEMDKILKKIDNCLTEM--ETETKN-----LEDEEKN--NPVEEW 2048 +Q A+ E + K ++K +++ N + ++ + E N L+ +++N + EW Sbjct: 1401 LQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEW 1460 Query: 2049 DSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLS 2105 + + ELE + E L L +++ E++L ++ ++++ ++ + L+ Sbjct: 1461 KQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLT 1517 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 51.6 bits (122), Expect = 9e-06 Identities = 50/205 (24%), Positives = 91/205 (44%), Gaps = 24/205 (11%) Query: 1904 EDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNL---WEKMRHCS 1960 E+ + ++ R K + R D ++I E A +++NK ++KMR Sbjct: 1123 EEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDL 1182 Query: 1961 DKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILK 2020 ++ ++ T T H VA G+ + + Q ++KL+ + EM Sbjct: 1183 EEAT---------LQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKM--- 1230 Query: 2021 KIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQK 2080 +ID+ + MET +K + EK RA E +L ++KT+EEE QR + +L Q+ Sbjct: 1231 EIDDLASNMETVSKAKGNLEKM---------CRALEDQLSEIKTKEEEQQRLINDLTAQR 1281 Query: 2081 EQTLAQIDFMQKQRNRTEELLDQLS 2105 + + +Q + + L+ QLS Sbjct: 1282 ARLQTESGEYSRQLDEKDTLVSQLS 1306 Score = 41.2 bits (95), Expect = 0.012 Identities = 44/219 (20%), Positives = 104/219 (47%), Gaps = 23/219 (10%) Query: 1904 EDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKE 1963 EDL + + + + + E R +E+ + S ++ L+D ++ + ++ H + Sbjct: 1669 EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERV--QLLHTQNTS 1726 Query: 1964 LKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDE---MDKILK 2020 L +N K T ++++ QG++ ++Q A+N EK + I + M + LK Sbjct: 1727 L------INTKKKLETDISQI---QGEME---DIIQEARNAEEKAKKAITDAAMMAEELK 1774 Query: 2021 KIDNCLTEMETETKNLEDEEKN--NPVEEWDS-EMRAAEKELEQLKTEEEELQRNLLELE 2077 K + +E KNLE K+ + ++E + ++ +K++++L+ EL+ E+E Sbjct: 1775 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEG---EVE 1831 Query: 2078 VQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSD 2116 ++++ + + ++K + +EL Q +++ D Sbjct: 1832 SEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQD 1870 Score = 37.4 bits (85), Expect = 0.17 Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 8/111 (7%) Query: 1998 VQSAQNEREKLQIKIDEMDKILKKIDNCLTEMET---ETKNLEDE--EKNNPVEEWDSEM 2052 ++++Q E L E+ KI + L ++ET E KNL+ E + + E + Sbjct: 1471 LEASQKESRSLST---ELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRI 1527 Query: 2053 RAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQ 2103 EK +Q++ E+ ELQ L E E E +I +Q + N+ + +D+ Sbjct: 1528 HELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1578 Score = 37.0 bits (84), Expect = 0.23 Identities = 33/193 (17%), Positives = 72/193 (37%), Gaps = 16/193 (8%) Query: 1917 IQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKS 1976 +Q R DC+ R++ EE + + + + + N + + ++ K Sbjct: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1396 Query: 1977 CFTKMTKVFTH----QGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETE 2032 ++ H K A K Q QNE E L I ++ + +D Sbjct: 1397 LAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDK-------- 1448 Query: 2033 TKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQK 2092 + + + EW + ELE + E L L +++ E++L Q++ +++ Sbjct: 1449 ----KQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKR 1504 Query: 2093 QRNRTEELLDQLS 2105 + ++ + L+ Sbjct: 1505 ENKNLQQEISDLT 1517 Score = 36.6 bits (83), Expect = 0.29 Identities = 39/194 (20%), Positives = 93/194 (47%), Gaps = 11/194 (5%) Query: 1922 EDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKM 1981 +D E K+E+ K + N+ K L + L E + + ++ + + + Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1018 Query: 1982 TKVFT-HQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEE 2040 KV T + K+ L ++ + ++ +I++D +++ +K++ L + T ++E+++ Sbjct: 1019 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMD-LERAKRKLEGDLKLAQESTMDIENDK 1077 Query: 2041 K--NNPVEEWDSEMRAAEKELE-------QLKTEEEELQRNLLELEVQKEQTLAQIDFMQ 2091 + + +++ + EM + ++E QL+ + +ELQ + ELE + E A + Sbjct: 1078 QQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAE 1137 Query: 2092 KQRNRTEELLDQLS 2105 KQR+ L+++S Sbjct: 1138 KQRSDLSRELEEIS 1151 Score = 36.2 bits (82), Expect = 0.39 Identities = 43/208 (20%), Positives = 91/208 (43%), Gaps = 33/208 (15%) Query: 1926 ARRQKIE----ELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKM 1981 A+++K+E ELK + + L + EK +H ++ ++K + + K+ Sbjct: 942 AKKRKLEDECSELKKDIDDLELTLAKV-----EKEKHATENKVKNLTEEMAGLDETIAKL 996 Query: 1982 TKVF-----THQ---GKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETET 2033 TK HQ + V + + KL+ ++D+++ L++ ++E Sbjct: 997 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK 1056 Query: 2034 KNLEDEEK---------NNPVEEWDSEMRAAEKELE--QLKTEEEE-----LQRNLLELE 2077 + LE + K N ++ D +++ E E+ Q K E+E+ LQ+ + EL+ Sbjct: 1057 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQ 1116 Query: 2078 VQKEQTLAQIDFMQKQRNRTEELLDQLS 2105 + E+ +I+ + R + E+ LS Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLS 1144 Score = 31.6 bits (70), Expect = 9.5 Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 9/119 (7%) Query: 2003 NEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQL 2062 N R + +K K+ KI L ETE + +E+ +E ++ A KELE+ Sbjct: 821 NVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEE- 879 Query: 2063 KTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLD---QLSLSEWDVVEWSDDQ 2118 K ++N L+L+VQ A+ D + R ++L+ QL +V E ++D+ Sbjct: 880 KMVTLMQEKNDLQLQVQ-----AEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDE 933 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 50.1 bits (118), Expect = 3e-05 Identities = 91/405 (22%), Positives = 162/405 (40%), Gaps = 57/405 (14%) Query: 1733 TEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHK-EKKIRKNEIKFSDTTQDR 1791 TE E E++ + K+ C+ K+ E + K EK+ E K + T++ Sbjct: 929 TERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 988 Query: 1792 EIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQF-- 1849 D E I K L K + +LD ++A+ ++ T ++E Q Sbjct: 989 AGLD----ETIAK-----LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1039 Query: 1850 LRDTICEES-LREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTV------NTPPT 1902 L ++ +E LR L+ + + L Q I+ + + L N Sbjct: 1040 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099 Query: 1903 PEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDK 1962 ED + KI+ + E ++IE + S + +K D+++ L E S++ Sbjct: 1100 IEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE----ISER 1155 Query: 1963 ELKAFG-----IYLNKIKSC-FTKMTKVFT----------------HQGKVALYGKLVQS 2000 +A G I +NK + F KM + H VA G+ + + Sbjct: 1156 LEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDN 1215 Query: 2001 AQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELE 2060 Q ++KL+ + EM +ID+ + +ET +K + EK R E +L Sbjct: 1216 LQRVKQKLEKEKSEMKM---EIDDLASNVETVSKAKGNLEKM---------CRTLEDQLS 1263 Query: 2061 QLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLS 2105 +LK++EEE QR + +L Q+ + + +Q + E L+ QLS Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLS 1308 Score = 42.0 bits (97), Expect = 0.007 Identities = 67/352 (19%), Positives = 150/352 (42%), Gaps = 45/352 (12%) Query: 1772 HKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDS-IKA 1830 H+E KI + +++ + + + +E+ID+ L +N R S S+LD+ I++ Sbjct: 1559 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ-----LKRNHIRIVESMQSTLDAEIRS 1613 Query: 1831 DGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSN 1890 ++ + ++ E L++ R T IL I + +S Sbjct: 1614 RNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQG---ILKDTQIHLDDALRSQ 1670 Query: 1891 LPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINK 1950 EDL + + + + + E R +E+ + S ++ L+D ++ Sbjct: 1671 -------------EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717 Query: 1951 NLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQI 2010 + ++ H + L +N K T ++++ QG++ ++Q A+N EK + Sbjct: 1718 RV--QLLHTQNTSL------INTKKKLETDISQM---QGEME---DILQEARNAEEKAKK 1763 Query: 2011 KIDE---MDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSE---MRAAEKELEQLKT 2064 I + M + LKK + +E KN+E K+ + ++E ++ +K++++L+ Sbjct: 1764 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA 1823 Query: 2065 EEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSD 2116 EL+ E+E ++++ + ++K R +EL Q +++ D Sbjct: 1824 RVRELEG---EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQD 1872 Score = 37.4 bits (85), Expect = 0.17 Identities = 40/200 (20%), Positives = 79/200 (39%), Gaps = 30/200 (15%) Query: 1917 IQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKS 1976 +Q R DC+ R++ EE + S + + L N + + ++ K Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398 Query: 1977 CFTKMTKVFTH----QGKVALYGKLVQSAQNEREKLQIKIDE-------MDKILKKIDNC 2025 ++ H K A K Q QNE E L + ++ +DK + D Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKI 1458 Query: 2026 LTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLA 2085 L E + + EE +E+ A++KE L TE L +++ E++L Sbjct: 1459 LAEWKQKC------------EETHAELEASQKEARSLGTE-------LFKIKNAYEESLD 1499 Query: 2086 QIDFMQKQRNRTEELLDQLS 2105 Q++ ++++ ++ + L+ Sbjct: 1500 QLETLKRENKNLQQEISDLT 1519 Score = 36.2 bits (82), Expect = 0.39 Identities = 45/203 (22%), Positives = 84/203 (41%), Gaps = 22/203 (10%) Query: 1920 YREDCEARRQKIEELK------LSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNK 1973 Y D R +++EE K L A+ + V+ EK + E++ + + + Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 Query: 1974 IKSCFTKMTKVFTHQGKVALYGKL--------VQSAQNEREKLQIKIDEMDKILKKIDNC 2025 + + K + K+ K ++++Q E L E+ KI + Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGT---ELFKIKNAYEES 1497 Query: 2026 LTEMET---ETKNLEDE--EKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQK 2080 L ++ET E KNL+ E + + E + EK +Q++ E+ ELQ L E E Sbjct: 1498 LDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASL 1557 Query: 2081 EQTLAQIDFMQKQRNRTEELLDQ 2103 E +I +Q + N+ + +D+ Sbjct: 1558 EHEEGKILRIQLELNQVKSEVDR 1580 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 50.1 bits (118), Expect = 3e-05 Identities = 91/405 (22%), Positives = 162/405 (40%), Gaps = 57/405 (14%) Query: 1733 TEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHK-EKKIRKNEIKFSDTTQDR 1791 TE E E++ + K+ C+ K+ E + K EK+ E K + T++ Sbjct: 929 TERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 988 Query: 1792 EIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQF-- 1849 D E I K L K + +LD ++A+ ++ T ++E Q Sbjct: 989 AGLD----ETIAK-----LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1039 Query: 1850 LRDTICEES-LREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTV------NTPPT 1902 L ++ +E LR L+ + + L Q I+ + + L N Sbjct: 1040 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099 Query: 1903 PEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDK 1962 ED + KI+ + E ++IE + S + +K D+++ L E S++ Sbjct: 1100 IEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE----ISER 1155 Query: 1963 ELKAFG-----IYLNKIKSC-FTKMTKVFT----------------HQGKVALYGKLVQS 2000 +A G I +NK + F KM + H VA G+ + + Sbjct: 1156 LEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDN 1215 Query: 2001 AQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELE 2060 Q ++KL+ + EM +ID+ + +ET +K + EK R E +L Sbjct: 1216 LQRVKQKLEKEKSEMKM---EIDDLASNVETVSKAKGNLEKM---------CRTLEDQLS 1263 Query: 2061 QLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLS 2105 +LK++EEE QR + +L Q+ + + +Q + E L+ QLS Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLS 1308 Score = 42.0 bits (97), Expect = 0.007 Identities = 67/352 (19%), Positives = 150/352 (42%), Gaps = 45/352 (12%) Query: 1772 HKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDS-IKA 1830 H+E KI + +++ + + + +E+ID+ L +N R S S+LD+ I++ Sbjct: 1559 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ-----LKRNHIRIVESMQSTLDAEIRS 1613 Query: 1831 DGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSN 1890 ++ + ++ E L++ R T IL I + +S Sbjct: 1614 RNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQG---ILKDTQIHLDDALRSQ 1670 Query: 1891 LPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINK 1950 EDL + + + + + E R +E+ + S ++ L+D ++ Sbjct: 1671 -------------EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717 Query: 1951 NLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQI 2010 + ++ H + L +N K T ++++ QG++ ++Q A+N EK + Sbjct: 1718 RV--QLLHTQNTSL------INTKKKLETDISQM---QGEME---DILQEARNAEEKAKK 1763 Query: 2011 KIDE---MDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSE---MRAAEKELEQLKT 2064 I + M + LKK + +E KN+E K+ + ++E ++ +K++++L+ Sbjct: 1764 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA 1823 Query: 2065 EEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSD 2116 EL+ E+E ++++ + ++K R +EL Q +++ D Sbjct: 1824 RVRELEG---EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQD 1872 Score = 37.4 bits (85), Expect = 0.17 Identities = 40/200 (20%), Positives = 79/200 (39%), Gaps = 30/200 (15%) Query: 1917 IQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKS 1976 +Q R DC+ R++ EE + S + + L N + + ++ K Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398 Query: 1977 CFTKMTKVFTH----QGKVALYGKLVQSAQNEREKLQIKIDE-------MDKILKKIDNC 2025 ++ H K A K Q QNE E L + ++ +DK + D Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKI 1458 Query: 2026 LTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLA 2085 L E + + EE +E+ A++KE L TE L +++ E++L Sbjct: 1459 LAEWKQKC------------EETHAELEASQKEARSLGTE-------LFKIKNAYEESLD 1499 Query: 2086 QIDFMQKQRNRTEELLDQLS 2105 Q++ ++++ ++ + L+ Sbjct: 1500 QLETLKRENKNLQQEISDLT 1519 Score = 36.2 bits (82), Expect = 0.39 Identities = 45/203 (22%), Positives = 84/203 (41%), Gaps = 22/203 (10%) Query: 1920 YREDCEARRQKIEELK------LSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNK 1973 Y D R +++EE K L A+ + V+ EK + E++ + + + Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440 Query: 1974 IKSCFTKMTKVFTHQGKVALYGKL--------VQSAQNEREKLQIKIDEMDKILKKIDNC 2025 + + K + K+ K ++++Q E L E+ KI + Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGT---ELFKIKNAYEES 1497 Query: 2026 LTEMET---ETKNLEDE--EKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQK 2080 L ++ET E KNL+ E + + E + EK +Q++ E+ ELQ L E E Sbjct: 1498 LDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASL 1557 Query: 2081 EQTLAQIDFMQKQRNRTEELLDQ 2103 E +I +Q + N+ + +D+ Sbjct: 1558 EHEEGKILRIQLELNQVKSEVDR 1580 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 49.7 bits (117), Expect = 3e-05 Identities = 83/395 (21%), Positives = 156/395 (39%), Gaps = 31/395 (7%) Query: 1733 TEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHK-EKKIRKNEIKFSDTTQDR 1791 TE E E++ + K+ C+ K+ E + K EK+ E K + T++ Sbjct: 924 TERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEL 983 Query: 1792 EIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQF-- 1849 D E I K L + + +LD ++A+ ++ S++E Q Sbjct: 984 SGLD----ETIAK-----LTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVED 1034 Query: 1850 LRDTICEES-LREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFT------VNTPPT 1902 L ++ +E LR L+ + + L Q IL + + L Sbjct: 1035 LESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSK 1094 Query: 1903 PEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDK 1962 ED ++ KI+ + E ++IE + + + +K D + L E + Sbjct: 1095 VEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEA 1154 Query: 1963 E-LKAFGIYLNKIKSC-FTKMTK-----VFTHQGKVALYGKLVQSAQNEREKLQIKIDEM 2015 + + I LNK + F K+ + H+ VA K + E L +ID + Sbjct: 1155 GGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAE---LGEQIDNL 1211 Query: 2016 DKILKKIDNCLTEMETETKNLED--EEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNL 2073 ++ +K++ +E + E +L E + + R E +L + + + EE+QR+L Sbjct: 1212 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSL 1271 Query: 2074 LELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSE 2108 EL QK + + + +Q E ++ QLS S+ Sbjct: 1272 SELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK 1306 Score = 39.3 bits (90), Expect = 0.045 Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 19/191 (9%) Query: 1954 EKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKID 2013 ++++ +KE F + ++ + S ++K A K+ ++ +++ + + K + Sbjct: 1212 QRVKQKLEKEKSEFKLEIDDLSSSMESVSK------SKANLEKICRTLEDQLSEARGKNE 1265 Query: 2014 EMDKILKKIDNCLTEMETETKNLED--EEKNNPVEEWDSEMRAAEKELEQLK--TEEEEL 2069 E+ + L ++ + ++TE L EEK + V + +A ++ E+LK EEE Sbjct: 1266 EIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK 1325 Query: 2070 QRNLLELEVQKEQ---TLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYD 2126 +N L +Q + L + + ++Q + EL LS + +V +W + D Sbjct: 1326 AKNALAHALQSSRHDCDLLREQYEEEQEGKA-ELQRALSKANSEVAQWRT-----KYETD 1379 Query: 2127 TIQLTITFEES 2137 IQ T EE+ Sbjct: 1380 AIQRTEELEEA 1390 Score = 38.9 bits (89), Expect = 0.059 Identities = 43/216 (19%), Positives = 99/216 (45%), Gaps = 17/216 (7%) Query: 1904 EDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKE 1963 EDL + + + + + E R +E+ + + ++ L+D N+ + ++ H + Sbjct: 1666 EDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV--QLLHTQNTS 1723 Query: 1964 LKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKID 2023 L ++ K T + ++ Q +V + ++A+ + +K M + LKK Sbjct: 1724 L------IHTKKKLETDLMQL---QSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 1774 Query: 2024 NCLTEMETETKNLEDEEKN--NPVEEWDS-EMRAAEKELEQLKTEEEELQRNLLELEVQK 2080 + +E KNLE K+ + ++E + ++ +K++++L+T EL+ ELE ++ Sbjct: 1775 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELE---FELEGEQ 1831 Query: 2081 EQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSD 2116 ++ + ++K R +EL Q +V+ D Sbjct: 1832 KKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQD 1867 Score = 37.7 bits (86), Expect = 0.13 Identities = 31/190 (16%), Positives = 86/190 (45%), Gaps = 10/190 (5%) Query: 1917 IQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWE-KMRHCSDKELKAFGIYLNKIK 1975 +Q R DC+ R++ EE + + + L N + + + ++ +D + + K K Sbjct: 1334 LQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1393 Query: 1976 SCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKN 2035 ++ + +V S + +++LQ +++++ +++ ++ ++ + +N Sbjct: 1394 LA----QRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRN 1449 Query: 2036 LEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRN 2095 + + EW ++ ++ ELE E L L +L+ E+ L Q++ ++++ Sbjct: 1450 FD-----KVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENK 1504 Query: 2096 RTEELLDQLS 2105 E+ + L+ Sbjct: 1505 NLEQEIADLT 1514 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 49.3 bits (116), Expect = 4e-05 Identities = 87/402 (21%), Positives = 169/402 (42%), Gaps = 52/402 (12%) Query: 1734 EEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKN----EIKFSDTTQ 1789 + K + +K EN+ G+ N K + + HK KK+ ++KF++ + Sbjct: 1207 QTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGER 1266 Query: 1790 DR-EIFDHHTEEDID-----------KSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDF 1837 R E+ D T+ ++ S +S L K+ S S + + ++ + Sbjct: 1267 VRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLS 1326 Query: 1838 STYRSSQMESQFLRDTICEESLREKLQD---GRITIREFFILLQVHILIQKPRQSNLPGN 1894 + + Q+E + + S RE+L++ + + + L + K + + Sbjct: 1327 LSTKLKQVEDE-------KNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED---- 1375 Query: 1895 FTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQ-DKLLVDINKNLW 1953 +V T E++ + E+ A K+E+ K + D LLVD++ Sbjct: 1376 -SVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDH--- 1431 Query: 1954 EKMRHCS-DKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYG--KLVQSAQNEREKLQI 2010 ++ C+ +K+ K F L + K+ K + A K + A+ E ++ Sbjct: 1432 QRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQ 1491 Query: 2011 KIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQ 2070 K E++++ K+ TEME + +D K+ V E + RA E+++E++KT+ EEL+ Sbjct: 1492 KA-ELERLNKQFR---TEMEDLMSSKDDVGKS--VHELEKSKRALEQQVEEMKTQLEELE 1545 Query: 2071 RNL-------LELEVQKEQTLAQID-FMQKQRNRTEELLDQL 2104 L L LEV + AQ + +Q + ++EE QL Sbjct: 1546 DELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQL 1587 Score = 40.0 bits (92), Expect = 0.027 Identities = 23/104 (22%), Positives = 56/104 (53%), Gaps = 3/104 (2%) Query: 1999 QSAQNEREKLQIKIDEMDKILK-KIDNCLTEMETETKNLEDEEKNNPVEEWDS--EMRAA 2055 Q + + ++L++K+ EM+ +K K +T +E + LE++ N E + ++R Sbjct: 1781 QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRT 1840 Query: 2056 EKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEE 2099 EK+L+ + + ++ +RN + + Q ++ ++ +++Q EE Sbjct: 1841 EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEE 1884 Score = 38.5 bits (88), Expect = 0.078 Identities = 68/308 (22%), Positives = 130/308 (42%), Gaps = 46/308 (14%) Query: 1844 QMESQFLRDT-ICEES--LREKLQDGRITIREFFILLQVHILIQKPRQSNLPGN---FTV 1897 Q++ Q +T +C E+ LR +L + + E L+ + ++ R +L Sbjct: 884 QLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ 943 Query: 1898 NTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMR 1957 N E L + R K+Q+ + EA+ +K+EE ++ +Q+ L K L +++ Sbjct: 944 NIQELEEQLEEEESA-RQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002 Query: 1958 HCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDK 2017 FT T + + K KL + K + I ++++ Sbjct: 1003 E-------------------FT--TNLTEEEEKSKSLAKL-------KNKHEAMITDLEE 1034 Query: 2018 ILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELE-QLKTEEEELQRNLLEL 2076 L++ + E+E + LE + + + + +E++A EL+ QL +EEELQ L + Sbjct: 1035 RLRREEKQRQELEKTRRKLEGDSTD--LSDQIAELQAQIAELKMQLAKKEEELQAALARV 1092 Query: 2077 E---VQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDD-----QAVFTFVYDTI 2128 E QK L +I ++ Q + +E L+ S + D +A+ T + DT+ Sbjct: 1093 EEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTL 1152 Query: 2129 QLTITFEE 2136 T +E Sbjct: 1153 DSTAAQQE 1160 Score = 37.0 bits (84), Expect = 0.23 Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 34/141 (24%) Query: 1997 LVQSAQNEREKLQIKIDEMDKILKK---IDNCLTEMETETKNLEDEE------------- 2040 L+Q ++ E E++ K +E+ K+ +K +N LTEMET L E+ Sbjct: 837 LLQVSRQE-EEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETEL 895 Query: 2041 -------------KNNPVEE--WDSEMRAAEKE--LEQLKTEEEELQRNLLELEVQKEQT 2083 K +EE D E R E+E + L+ E++++Q+N+ ELE Q E+ Sbjct: 896 CAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEE 955 Query: 2084 LAQIDFMQKQRNRTEELLDQL 2104 + +Q ++ TE L +L Sbjct: 956 ESARQKLQLEKVTTEAKLKKL 976 Score = 35.0 bits (79), Expect = 0.86 Identities = 89/459 (19%), Positives = 178/459 (38%), Gaps = 74/459 (16%) Query: 1678 TTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEKA 1737 T D + LE+Q +++ KL+LS E+ + +++ + E++ Sbjct: 1300 TKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ- 1358 Query: 1738 LIETYQKEISPYENKMG------KTCNSQKRTWVQEEEDI---HKEKKIRKNEIKFSDTT 1788 I T +++ + KM +T KR ++ E + H+EK ++++ + T Sbjct: 1359 -IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTR 1417 Query: 1789 QDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQ 1848 +E+ D + D + S+C+ K D + T + E Sbjct: 1418 LQQELDDLLVDLDHQRQ-------------SACNLEKKQKKFDQLLAEEKTISAKYAEE- 1463 Query: 1849 FLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLML 1908 RD E REK R ++ QK L F EDLM Sbjct: 1464 --RDR-AEAEAREKETKALSLARALEEAME-----QKAELERLNKQFRTEM----EDLMS 1511 Query: 1909 SQYVYRPKIQIYREDCEARRQKIEELK---------LSASNQDKLLVDINKNLWEKMRHC 1959 S+ + + A Q++EE+K L A+ KL +++N + M+ Sbjct: 1512 SKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNL---QAMKAQ 1568 Query: 1960 SDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEM---- 2015 +++L+ + K + + + ++ K A R+KL++ + ++ Sbjct: 1569 FERDLQGRDEQSEEKKKQLVRQVREM--EAELEDERKQRSMAVAARKKLEMDLKDLEAHI 1626 Query: 2016 -------DKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEE 2068 D+ +K++ +M+ + L+D + EE ++ + EK+L+ ++ E + Sbjct: 1627 DSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASR--EEILAQAKENEKKLKSMEAEMIQ 1684 Query: 2069 LQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLS 2107 LQ L E K Q Q++R +EL D+++ S Sbjct: 1685 LQEELAAAERAKRQA-------QQER---DELADEIANS 1713 Score = 35.0 bits (79), Expect = 0.86 Identities = 30/168 (17%), Positives = 75/168 (44%), Gaps = 7/168 (4%) Query: 1928 RQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTK--VF 1985 R K L++ N D L + E R +++ K + L +++ K + Sbjct: 1751 RLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810 Query: 1986 THQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPV 2045 + K+A +L + NE ++ Q ++ + KK+ + L +++ E +N E+ + Sbjct: 1811 ALEAKIA---QLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNA--EQYKDQA 1865 Query: 2046 EEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQ 2093 ++ + ++ +++LE+ + E + + +L+ + E D M ++ Sbjct: 1866 DKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNRE 1913 Score = 34.3 bits (77), Expect = 1.5 Identities = 39/209 (18%), Positives = 88/209 (42%), Gaps = 14/209 (6%) Query: 1906 LMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELK 1965 LM + + ++Q E C + L +++ D+ + E+ C + + Sbjct: 878 LMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAE 937 Query: 1966 AFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNC 2025 + N I+ ++ + + + K+ L ++ + E+ QI +++ + L K Sbjct: 938 KKKMQQN-IQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKL 996 Query: 2026 LTEMETE-TKNLEDEEKNNP------------VEEWDSEMRAAEKELEQLKTEEEELQRN 2072 L + E T NL +EE+ + + + + +R EK+ ++L+ +L+ + Sbjct: 997 LEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGD 1056 Query: 2073 LLELEVQKEQTLAQIDFMQKQRNRTEELL 2101 +L Q + AQI ++ Q + EE L Sbjct: 1057 STDLSDQIAELQAQIAELKMQLAKKEEEL 1085 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 49.3 bits (116), Expect = 4e-05 Identities = 100/493 (20%), Positives = 203/493 (41%), Gaps = 76/493 (15%) Query: 1708 SQYINEENLPV--------YPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNS 1759 ++ +N+EN+ Y + + + + E EE L + ++ +E KT Sbjct: 488 TKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKD 547 Query: 1760 QKRTWVQEEEDIH---KEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSR 1816 Q+ + E ++ K ++ +++ ++ + E+ E+ I K + + L Sbjct: 548 QEMQLIHEISNLKNLVKHAEVYNQDLE-NELSSKVELL-REKEDQIKKLQEYIDSQKLEN 605 Query: 1817 TPSSCSSSLDSIK----ADGTSLDFSTYR-SSQMESQFLRDTICEESLREKLQDGRITIR 1871 S SL+SI+ T D T ++ ES FLR E L+EK+++ T + Sbjct: 606 IKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLE--LKEKMKELATTYK 663 Query: 1872 EF---FILLQVHILIQKPRQ----SNLPGNFTVNTPPT-------PEDLMLSQYVYRPKI 1917 + L Q + +K Q L F T T P+DL+ + + Sbjct: 664 QMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKIT 723 Query: 1918 QIYRE------DCEARRQKI---EELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFG 1968 + +E + EA R+++ ELK S ++L +I E S+K+ K F Sbjct: 724 DLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKD-KLFS 782 Query: 1969 IYLNKIKSCFTKMTKVFTHQGKVAL----YGKLVQSAQN-----------------EREK 2007 ++K + ++ + +A Y Q QN E E+ Sbjct: 783 EVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENER 842 Query: 2008 LQIKIDEMDKILKKIDNCLTEMETET--KNLEDEEKNNPVEEWDSEMRAAEKELEQLKTE 2065 + +I + K +K D+ L ++TE K E +EK V+E +EM +++LE + Sbjct: 843 MNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDST 902 Query: 2066 EEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVY 2125 + ++R + + +QTL ++ + ++++ ++L + L + DQ + + ++ Sbjct: 903 LQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIER--------DQ-LKSDIH 953 Query: 2126 DTIQLTITFEESV 2138 DT+ + I +E + Sbjct: 954 DTVNMNIDTQEQL 966 Score = 43.1 bits (100), Expect = 0.003 Identities = 72/380 (18%), Positives = 156/380 (41%), Gaps = 55/380 (14%) Query: 1733 TEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDRE 1792 +E++ I T QK++ +K+ K + E+E+ K+I + + K ++ Q +E Sbjct: 1501 SEKETEISTIQKQLEAINDKL-----QNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKE 1555 Query: 1793 IFDHHTEED----------------IDKSANSVLI-----KNLSRTPSSCSSSLDSIKAD 1831 H +D + +S + I + + R + D +K + Sbjct: 1556 ---HRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKEN 1612 Query: 1832 GTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNL 1891 + S + E QFL+ T E+ +EK+ + +F + ++ NL Sbjct: 1613 TKEIVAKMKESQEKEYQFLKMTAVNET-QEKMCEIEHLKEQF-----------ETQKLNL 1660 Query: 1892 PGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQ--KIEELKLSASNQDKLLVDIN 1949 T N T ++ + R+D + + K+E +L + ++ + D+ Sbjct: 1661 ENIETENIRLT--QILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLE 1718 Query: 1950 KNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQ 2009 K K+ H KE + ++K++ ++ T ++ K + AQ+ + + + Sbjct: 1719 KQEELKIVHMHLKEHQET---IDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEE 1775 Query: 2010 IKI-----DEMDKILKKIDNCLTEMETETKNLED--EEKNNPVEEWDSEMRAAEKELEQL 2062 ++I E + + K+ ++E + N++ E N ++E E++A E +L L Sbjct: 1776 LRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITL 1835 Query: 2063 KTEEEELQRNLLELEVQKEQ 2082 K + E Q+ + E+E K+Q Sbjct: 1836 KKDVNETQKKVSEMEQLKKQ 1855 Score = 40.4 bits (93), Expect = 0.020 Identities = 87/446 (19%), Positives = 187/446 (41%), Gaps = 77/446 (17%) Query: 1693 DSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEK-ALIETYQKEISPYEN 1751 DS +G++ +L+ +Q + E+ V + +N + + + E + + ++T ++E + Sbjct: 858 DSSLGALKTELSYK-TQELQEKTREVQ-ERLNEMEQLKEQLENRDSTLQTVEREKTLITE 915 Query: 1752 KMGKTCNSQKRTWVQEEEDI---HKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANS 1808 K+ +T K T QE++D+ + +I ++++K DI + N Sbjct: 916 KLQQTLEEVK-TLTQEKDDLKQLQESLQIERDQLK----------------SDIHDTVNM 958 Query: 1809 VLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRI 1868 + T ++L+S+K +++ S++ + R+ EE+ E Sbjct: 959 NI-----DTQEQLRNALESLKQHQETINTL---KSKISEEVSRNLHMEENTGE------- 1003 Query: 1869 TIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARR 1928 T EF Q + I K + T+ +++ Q R + +E E ++ Sbjct: 1004 TKDEF---QQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQ---RKIFSLIQEKNELQQ 1057 Query: 1929 QKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTK-MTKVFTH 1987 L+ + +++L D+ +N+ +M + +EL+ G L K + + Sbjct: 1058 M----LESVIAEKEQLKTDLKENI--EMTIENQEELRLLGDELKKQQEIVAQEKNHAIKK 1111 Query: 1988 QGKVA--------LYGKLVQSAQNEREK------LQIKIDEMDKILKKIDNCLTEMET-- 2031 +G+++ + KL + +Q +EK +Q ++ EM K + +I+N E++ Sbjct: 1112 EGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKE 1171 Query: 2032 ------ETKNLEDEEKNNPVEEWDSEMRAAEKELEQLK----TEEEELQRNLLELEVQKE 2081 ET+ LE +K N E + K L++L+ TE + L+ + E+E Sbjct: 1172 LTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGL 1231 Query: 2082 QTLAQIDFMQKQRNRTEELLDQLSLS 2107 QT ++ +E +D+L S Sbjct: 1232 QTKEELKIAHIHLKEHQETIDELRRS 1257 Score = 38.1 bits (87), Expect = 0.10 Identities = 139/734 (18%), Positives = 288/734 (39%), Gaps = 107/734 (14%) Query: 1402 QTLVYSQDLGEMTKLNSKRVSFKLPKDQ--MKVYVDDIYVIPQPHFSTDQPPLPKKGQSS 1459 Q+L + E TK+ S+ FK PKD +++ ++ + + + S D+ K + Sbjct: 1388 QSLNMKEKDNETTKIVSEMEQFK-PKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDD 1446 Query: 1460 INK-EEVILSKAGNKSLNIIENSSAPICENKPKILNSEEWFAAA--CKKELKENIQTTNY 1516 + + +EV+ S++ NI E + K L +EE A C KE +E I Sbjct: 1447 LQRLQEVLQSESDQLKENIKEIVA--------KHLETEEELKVAHCCLKEQEETINELRV 1498 Query: 1517 NTALDFHSNSDVTKQV------IQTHVNAGEAPDPVITSNVPCFHSIKPNLNNLNGKTGE 1570 N + S + KQ+ +Q + E + N+ ++ +N L + E Sbjct: 1499 NLSEKETEISTIQKQLEAINDKLQNKIQ--EIYEKEEQFNIKQISEVQEKVNELK-QFKE 1555 Query: 1571 FLAFQTVHLPPLPEQLLELGNKAHNDMHIVQAT-----EIHNINIISSNAKDSRDEENK- 1624 + L + ++LEL N+ +Q E+ + +D E K Sbjct: 1556 HRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKE 1615 Query: 1625 -----KSHNGAETTSLPPKTVFKDKVRRCSLGIFLPRLPNKRNCSVTGIDDLEQIPADTT 1679 K E L V + + + C + L + ++++E T Sbjct: 1616 IVAKMKESQEKEYQFLKMTAVNETQEKMCEI----EHLKEQFETQKLNLENIETENIRLT 1671 Query: 1680 DINHL---ETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINI----- 1731 I H E + V+ + + SV EE L V D++ + I Sbjct: 1672 QILHENLEEMRSVTKERDDLRSV-------------EETLKVERDQLKENLRETITRDLE 1718 Query: 1732 ETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDI-HKEKKIRKNEIKFSDTTQD 1790 + EE ++ + KE +K+ + + ++D+ H ++ ++K + + Sbjct: 1719 KQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRI 1778 Query: 1791 REIFDHHTEEDIDKSANSV---------LIKNLSRTPSSCSSSLDSIKADGTSLDFSTYR 1841 + +E IDK V + K+L + + + +KA+ L T + Sbjct: 1779 AHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQL--ITLK 1836 Query: 1842 SSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTV---- 1897 E+Q + E L+++++D +T+ + I ++ + + NL +V Sbjct: 1837 KDVNETQ--KKVSEMEQLKKQIKDQSLTLSKLEI---ENLNLAQKLHENLEEMKSVMKER 1891 Query: 1898 -NTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIE-ELKLSASNQDKLLVDINKNLWEK 1955 N E L L + + +Q + +AR +I+ ELK + ++L +K +K Sbjct: 1892 DNLRRVEETLKLERDQLKESLQ----ETKARDLEIQQELKTA-----RMLSKEHKETVDK 1942 Query: 1956 MRH-CSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDE 2014 +R S+K ++ I + KS K L K+ + + E + L++K ++ Sbjct: 1943 LREKISEKTIQISDIQKDLDKS-------------KDELQKKIQELQKKELQLLRVK-ED 1988 Query: 2015 MDKILKKIDNC-LTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNL 2073 ++ KKI+ + + E +NL + + ++ + +E+ + E +EL+R Sbjct: 1989 VNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIK 2048 Query: 2074 LELEVQKEQTLAQI 2087 L+++++Q +A + Sbjct: 2049 ESLKMERDQFIATL 2062 Score = 37.0 bits (84), Expect = 0.23 Identities = 115/581 (19%), Positives = 219/581 (37%), Gaps = 90/581 (15%) Query: 1713 EENLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIH 1772 EE L ++ + +E+ + QK+I+ EN + N + E E + Sbjct: 1126 EEKLKEKSQQLQEKQQQLLNVQEE--MSEMQKKINEIENLKNELKNKELTLEHMETERLE 1183 Query: 1773 KEKKIRKNEIKFSDTTQDREIFDH-----HTEEDIDKSANSVLIKNLSRTPSSCSSSLDS 1827 +K+ +N + T++R++ TE D + + +T + Sbjct: 1184 LAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIH 1243 Query: 1828 IKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPR 1887 +K ++D S+ +Q + E+S + LQ I + Sbjct: 1244 LKEHQETIDELRRSVSEKTAQIINTQDLEKSHTK---------------LQEEIPVLHEE 1288 Query: 1888 QSNLPGNFTVN-TPPTPEDLML--SQYVYRPKIQIYREDCEARR------QKIEELKLSA 1938 Q LP V+ T T +L L Q + + R + E R + EE+K Sbjct: 1289 QELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLT 1348 Query: 1939 SNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLV 1998 +D L K + E + D+ + L KI+ +K + + K K+V Sbjct: 1349 KERDNL-----KTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIV 1403 Query: 1999 QSAQNEREK----LQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSE-MR 2053 + + K L+I+I EM + K++ EM++ K +D ++ V + +S+ ++ Sbjct: 1404 SEMEQFKPKDSALLRIEI-EMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLK 1462 Query: 2054 AAEKEL--EQLKTEEE---------ELQRNLLELEVQKEQTLAQIDFMQKQ--------R 2094 KE+ + L+TEEE E + + EL V + +I +QKQ + Sbjct: 1463 ENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQ 1522 Query: 2095 NRTEEL--------LDQLS--------LSEWDVVEWSDDQAVFTFVYDTIQLTITFEESV 2138 N+ +E+ + Q+S L ++ + D A+ + ++LT +ES Sbjct: 1523 NKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQ 1582 Query: 2139 VGFPFLDKRYRKIVDVNFQSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQLPK 2198 + K ++ V ++ DQ ++ + + + E++ + K K Sbjct: 1583 EEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEK 1642 Query: 2199 MLEEFSLVVHHCRLLGEEIEYLKRWGPNYNLMNIDINNNEL 2239 M E + H L E+ E K NL NI+ N L Sbjct: 1643 MCE-----IEH---LKEQFETQK-----LNLENIETENIRL 1670 Score = 36.6 bits (83), Expect = 0.29 Identities = 73/327 (22%), Positives = 136/327 (41%), Gaps = 66/327 (20%) Query: 1908 LSQYVYRPKIQIYREDCEARRQKIEELK-------------LSASNQDKLLVDINKNLWE 1954 L +Y+ K++ + D + IE+ K L A + L N L E Sbjct: 594 LQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKE 653 Query: 1955 KMRHCS------DKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKL 2008 KM+ + + +++ + L K + K +QSA NE KL Sbjct: 654 KMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKE-------------LQSAFNEITKL 700 Query: 2009 QIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWD---------SEMRAAEKEL 2059 ID K+ K + C E+E + +L+ +E N VEE + SE+++ E+ Sbjct: 701 TSLID--GKVPKDL-LCNLELEGKITDLQ-KELNKEVEENEALREEVILLSELKSLPSEV 756 Query: 2060 EQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQA 2119 E+L+ E ++ L + +K++ +++ + +R + LL+++ ++ DD A Sbjct: 757 ERLRKEIQDKSEELHIITSEKDKLFSEV---VHKESRVQGLLEEIGKTK-------DDLA 806 Query: 2120 VFTFVY-DTIQLTITFEESVVGFPFLDKRYRKIVDVN------FQSLLDEDQAPPSSLLV 2172 Y T Q F+ + F +++Y+ +++ N +L E Q SSL Sbjct: 807 TTQSNYKSTDQEFQNFKTLHMDF---EQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGA 863 Query: 2173 HKLIFQYVEEKESWKKTCTTQHQLPKM 2199 K Y + +E +KT Q +L +M Sbjct: 864 LKTELSY-KTQELQEKTREVQERLNEM 889 Score = 34.3 bits (77), Expect = 1.5 Identities = 47/264 (17%), Positives = 110/264 (41%), Gaps = 24/264 (9%) Query: 1916 KIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSD-----KELKAFGIY 1970 K+ ++D E K++E + L+ + K++ E + S+ K++K + Sbjct: 1803 KLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT 1862 Query: 1971 LNKIK-SCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEM 2029 L+K++ K+ + ++ K + + E L+++ D++ + L++ E+ Sbjct: 1863 LSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEI 1922 Query: 2030 ETETKN---LEDEEKNN------PVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQK 2080 + E K L E K + E ++ +K+L++ K E ++ + L + E+Q Sbjct: 1923 QQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQL 1982 Query: 2081 EQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVG 2140 + ++ K+ N E+L Q + + ++ + D QLT ES+ Sbjct: 1983 LRVKEDVNMSHKKINEMEQLKKQFE---------AQNLSMQSVRMDNFQLTKKLHESLEE 2033 Query: 2141 FPFLDKRYRKIVDVNFQSLLDEDQ 2164 + K ++ + ++ DQ Sbjct: 2034 IRIVAKERDELRRIKESLKMERDQ 2057 Score = 33.9 bits (76), Expect = 1.9 Identities = 76/385 (19%), Positives = 156/385 (40%), Gaps = 26/385 (6%) Query: 1722 EINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNE 1781 E ++ ++ + ++ +IE +K S + K + + E+E + + K E Sbjct: 1022 EAKNTQTLTADVKDNEIIEQQRKIFSLIQEK--NELQQMLESVIAEKEQLKTDLK-ENIE 1078 Query: 1782 IKFSDTTQDREIFDH--HTEEDIDKSANSVLIKN--LSRTPSSCSSSLDSIKADGTSLDF 1837 + + + R + D +E + + N + K LSRT + + +K L Sbjct: 1079 MTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQE 1138 Query: 1838 STYR--SSQMESQFLRDTICE-ESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGN 1894 + + Q E ++ I E E+L+ +L++ +T+ + + L QK ++ Sbjct: 1139 KQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEH--METERLELAQKLNENYEEVK 1196 Query: 1895 FTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARR-QKIEELKLSASNQDKLLVDINKNLW 1953 ++L S R ++ Y + EA Q EELK++ + L + + + Sbjct: 1197 SITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIH----LKEHQETID 1252 Query: 1954 EKMRHCSDKELKAFGIY-LNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKI 2012 E R S+K + L K + + V + ++ K V Q +L++ Sbjct: 1253 ELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLT 1312 Query: 2013 DEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRN 2072 ++ K L +E E L N +E E+++ KE + LKT +E L+ Sbjct: 1313 EQSTT---KDSTTLARIEMERLRL-----NEKFQESQEEIKSLTKERDNLKTIKEALEVK 1364 Query: 2073 LLELEVQKEQTLAQIDFMQKQRNRT 2097 +L+ +TLA+I Q ++ ++ Sbjct: 1365 HDQLKEHIRETLAKIQESQSKQEQS 1389 Score = 32.3 bits (72), Expect = 5.6 Identities = 23/115 (20%), Positives = 55/115 (47%), Gaps = 14/115 (12%) Query: 1986 THQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPV 2045 TH+ + L ++ +S +E + +D + +I E TK L E + + Sbjct: 450 THKLSINLLREIDESVCSESDVFSNTLDTLSEI---------EWNPATKLLNQENIESEL 500 Query: 2046 EEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEEL 2100 ++ + EQL+TE+EE +EL+++++ L + + ++++ + +E+ Sbjct: 501 NSLRADYDNLVLDYEQLRTEKEE-----MELKLKEKNDLDEFEALERKTKKDQEM 550 Score = 32.3 bits (72), Expect = 5.6 Identities = 30/161 (18%), Positives = 81/161 (50%), Gaps = 21/161 (13%) Query: 1916 KIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIK 1975 KIQ ++DC+ +++ +LKL+ N D + +I K+ E ++ Sbjct: 2211 KIQHLQQDCDVPSRELRDLKLN-QNMDLHIEEILKDFSE-----------------SEFP 2252 Query: 1976 SCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTE--METET 2033 S T+ +V +++ ++ + + + + + EKL+ I + + + +++N + Sbjct: 2253 SIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMN 2312 Query: 2034 KNLEDEEKNNPV-EEWDSEMRAAEKELEQLKTEEEELQRNL 2073 ++ E EE++ + +EW+ ++++ +++ E+L + L+ +L Sbjct: 2313 ESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSL 2353 >gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] Length = 1140 Score = 49.3 bits (116), Expect = 4e-05 Identities = 91/455 (20%), Positives = 189/455 (41%), Gaps = 68/455 (14%) Query: 1680 DINHLETQPVSSKDSGIGSVAGKL-NLSPSQYINEENLPVYPDEINSSDS--INIETEEK 1736 +I HL+ V + G+GS G + +L SQ + L + D + + +N+E E + Sbjct: 551 EIGHLQDM-VRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELE 609 Query: 1737 ALIETYQKEISPYEN----KMGKTCNSQKRTWV----QEEEDIHKEKKIRKNEIKFSDTT 1788 + +++ I+ + K+ K + + W QE + +E +++ E K S + Sbjct: 610 QERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMS 669 Query: 1789 QDREIFDHHT-------EEDIDKSAN--SVLIKNLSRTPSSCSSSLDSIKADGTSLDFST 1839 Q ++ D ++ ++ N S+L +NL S +SL ++A T Sbjct: 670 QLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQ----- 724 Query: 1840 YRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNT 1899 E Q L + E L E+ Q +++E +L + +K ++ N Sbjct: 725 ------ERQRLTQEL--EELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQK 776 Query: 1900 PPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDK-LLVDINKNLWEK--- 1955 +L + +R ++ +R + E Q+++ L+ ++ K +L + L + Sbjct: 777 HSA--ELQSLKDAHRESMEGFRIEME---QELQTLRFELEDEGKAMLASLRSELNHQHAA 831 Query: 1956 ----MRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIK 2011 +RH +EL A + L + + +K + + Q E + Sbjct: 832 AIDLLRHNHHQELAAAKMELERSIDISRRQSKEHICR---------ITDLQEELRHREHH 882 Query: 2012 IDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQR 2071 I E+DK ++ + ++ + TK LE + K +R + +Q++ E++L + Sbjct: 883 ISELDKEVQHLHENISAL---TKELEFKGKEI--------LRIRSESNQQIRLHEQDLNK 931 Query: 2072 NL-LELEVQKEQTLAQIDFMQKQRNRTEELLDQLS 2105 L EL+V L + + M+ N+T ELL +++ Sbjct: 932 RLEKELDVMTADHLREKNIMRADFNKTNELLKEIN 966 Score = 39.3 bits (90), Expect = 0.045 Identities = 63/312 (20%), Positives = 128/312 (41%), Gaps = 39/312 (12%) Query: 1923 DCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMT 1982 + E RQ+ EE + ++KL VD KM H D E+K + L + S + Sbjct: 607 ELEQERQQHEETIAAMKEEEKLKVD-------KMAH--DLEIK-WTENLRQECSKLREEL 656 Query: 1983 KVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKN 2042 ++ + K + +L+Q E+ + D KK+++ L ++ +NLE + Sbjct: 657 RLQHEEDKKSAMSQLLQLKDREKNAAR------DSWQKKVEDLLNQISLLKQNLEIQLSQ 710 Query: 2043 NPVE------EWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNR 2096 + ++ E + +ELE+L+ + ++ ++L E V QT+ + +K++ Sbjct: 711 SQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTME--EEKEKEQRA 768 Query: 2097 TEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNF 2156 E L Q +E ++ + +++ F I E+ + F + K + + Sbjct: 769 LENHLQQKHSAELQSLKDAHRESMEGF-------RIEMEQELQTLRFELEDEGKAMLASL 821 Query: 2157 QSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQLPK--------MLEEFSLVVH 2208 +S L+ A LL H + K +++ + K + EE H Sbjct: 822 RSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHICRITDLQEELRHREH 881 Query: 2209 HCRLLGEEIEYL 2220 H L +E+++L Sbjct: 882 HISELDKEVQHL 893 Score = 38.5 bits (88), Expect = 0.078 Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 3/114 (2%) Query: 1990 KVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWD 2049 K+ Y V + R K+Q+ ++ +K LTE E +ED + + Sbjct: 90 KILQYKSKVTEELDLRRKIQVLESSLEDHIKMKQQALTEFEAYKHRVEDMQLCAEAQH-V 148 Query: 2050 SEMRAAEKELEQLKTEEEELQRNLLELEVQ--KEQTLAQIDFMQKQRNRTEELL 2101 + +E+E+++ + EE R+ +L+VQ K++ LA D R +ELL Sbjct: 149 QRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLQAAHRREIQELL 202 >gi|34878904 synaptonemal complex protein 1 [Homo sapiens] Length = 976 Score = 48.5 bits (114), Expect = 7e-05 Identities = 87/449 (19%), Positives = 184/449 (40%), Gaps = 64/449 (14%) Query: 1722 EINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQE--------EEDIHK 1773 ++ ++ + +E +K L E KE YENK + + + QE E+++H Sbjct: 424 KLTNNKEVELEELKKVLGE---KETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVH- 479 Query: 1774 EKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGT 1833 + +I+ I S+ +E+ D TE + +K N+ L + ++ SL++ + Sbjct: 480 DLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKL------SLENKELTQE 533 Query: 1834 SLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPG 1893 + D + +Q E + K Q+ R+ L Q+ L + Q Sbjct: 534 TSDMTLELKNQQE----------DINNNKKQEERM-------LKQIENLQETETQLRNEL 576 Query: 1894 NFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDI---NK 1950 + E+L + + K+ E+C R+++E N++K + ++ NK Sbjct: 577 EYV------REELKQKRDEVKCKLDKSEENCNNLRKQVE-------NKNKYIEELQQENK 623 Query: 1951 NLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVF-----THQGKVALYGKLVQSAQNER 2005 L +K K+L + I +NK++ + F T+Q ++ ++ E Sbjct: 624 AL-KKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEV 682 Query: 2006 EKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTE 2065 EK ++ DE K+ K+ID E L ++ K+ ++D + + EL K++ Sbjct: 683 EKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKH----QYDKIIEERDSELGLYKSK 738 Query: 2066 EEELQRNLLELEVQKEQTLAQIDFMQKQ---RNRTEELLDQLSLSEWDVVEWSDDQAVFT 2122 E+E LE++ A++ ++KQ +E L + + ++ D+ T Sbjct: 739 EQEQSSLRASLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQT 798 Query: 2123 FVYDTIQLTITFEESVVGFPFLDKRYRKI 2151 F+ +T ++ + V + + + + Sbjct: 799 FLLETPEIYWKLDSKAVPSQTVSRNFTSV 827 Score = 42.0 bits (97), Expect = 0.007 Identities = 83/420 (19%), Positives = 167/420 (39%), Gaps = 40/420 (9%) Query: 1709 QYINEENLPVYPD-------EINSSDSINIETEEKALI------ETYQKEISPYENKMGK 1755 +Y EE VY D I + + + ++ E L E Y+K I E + K Sbjct: 201 EYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEK-IQHLEQEYKK 259 Query: 1756 TCNSQKRT------WVQEEEDIHKEKK--IRKNEIKFSDTTQDREIFDHHTEEDIDKSAN 1807 N +++ + E+E+ K+ + ++ K + + ++ + ++ I+K + Sbjct: 260 EINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHH 319 Query: 1808 SVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGR 1867 L K L S S+ + KA L +T Q+ + ++T EES + + Sbjct: 320 --LTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEE--KETQMEESNKARAAHSF 375 Query: 1868 ITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEAR 1927 + + EF + + + Q L N + L + + K E + Sbjct: 376 V-VTEFETTVCSLEELLRTEQQRLEKN--------EDQLKILTMELQKKSSELEEMTKLT 426 Query: 1928 RQK---IEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKV 1984 K +EELK ++ LL + NK + E + G+ + K ++ Sbjct: 427 NNKEVELEELKKVLGEKETLLYE-NKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQL 485 Query: 1985 FTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNP 2044 Y K V+ + E E ++K E+ K+ E+ ET ++ E KN Sbjct: 486 TAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQ 545 Query: 2045 VEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQL 2104 E+ ++ + E+ L+Q++ +E + ELE +E+ + D ++ + +++EE + L Sbjct: 546 -EDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNL 604 Score = 37.7 bits (86), Expect = 0.13 Identities = 48/241 (19%), Positives = 99/241 (41%), Gaps = 32/241 (13%) Query: 1904 EDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKE 1963 +DL+ R + +E C +K ++ + ++ +D+N N+ + + + Sbjct: 170 KDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELR 229 Query: 1964 LKAFGIYLN---KIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILK 2020 ++A L K+K + K+ Q Y K + + + L I+I E + +K Sbjct: 230 VQAENSRLEMHFKLKEDYEKI------QHLEQEYKKEINDKEKQVSLLLIQITEKENKMK 283 Query: 2021 KIDNCLTEMETETKNLEDEEK--NNPVEEWDSEMRAAEKELEQLKTE-----------EE 2067 + L E + LE++ K + +++ + KELE +K EE Sbjct: 284 DLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEE 343 Query: 2068 ELQ---RNLLELEVQKEQTL-------AQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDD 2117 +LQ + + +L +KE + A F+ + T L++L +E +E ++D Sbjct: 344 DLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNED 403 Query: 2118 Q 2118 Q Sbjct: 404 Q 404 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 47.4 bits (111), Expect = 2e-04 Identities = 50/234 (21%), Positives = 104/234 (44%), Gaps = 22/234 (9%) Query: 1902 TPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDIN-KNLWEKMRHCS 1960 T E LS +YR I E+ + + K++E KL +K + +N K L K+ Sbjct: 199 TKERDALSLELYRNTIT--DEELKEKNAKLQE-KLQLVESEKSEIQLNVKELKRKLERAK 255 Query: 1961 ----DKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMD 2016 ++L+A +L K + + + + L+ +L Q + + + + KI E + Sbjct: 256 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE--LWNRLNQQQEEKMWRQEEKIQEWE 313 Query: 2017 KILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLEL 2076 + +++ + + E E + + E EEK EE E + E++ E+EE R L E+ Sbjct: 314 EKIQEQEEKIREQEEKIR--EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEM 371 Query: 2077 EVQKEQTLAQID----------FMQKQRNRTEELLDQLSLSEWDVVEWSDDQAV 2120 +KE+ + +++ +++R E++ +Q E + W ++ + Sbjct: 372 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425 Score = 37.7 bits (86), Expect = 0.13 Identities = 35/199 (17%), Positives = 96/199 (48%), Gaps = 6/199 (3%) Query: 1904 EDLMLSQYVYRPKIQIY-REDCEARRQKIEELKLSASNQDKLLVDINKNLW---EKMRHC 1959 E + + ++R K +++ +E + +K+ + +Q++ + + + +W EK+R Sbjct: 469 EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ 528 Query: 1960 SDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKIL 2019 +K + + + + K+ + K+ K+ + + RE+ + KI E + + Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE-KIREQKEKI 587 Query: 2020 KKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQ 2079 ++ + + E E + + E+ + + W+ E + E+E E+++ +EE+++R ++ Q Sbjct: 588 REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQE-EKMQEQEEKMRRQEEKMWEQ 646 Query: 2080 KEQTLAQIDFMQKQRNRTE 2098 + + Q + MQ+ + E Sbjct: 647 EVRLRQQEEKMQEHQEHLE 665 Score = 37.4 bits (85), Expect = 0.17 Identities = 78/440 (17%), Positives = 177/440 (40%), Gaps = 67/440 (15%) Query: 1683 HLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEKALIETY 1742 HL T P+ SK++ +A +E L + + N S A +T Sbjct: 44 HLPTHPMMSKETRQSKLAEA----------KEQLTDHHPQTNPSVGT-------AASDTK 86 Query: 1743 QKEISPYENKMGKT---CNS---QKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREI--- 1793 +K+I+ N T C+S +++ Q +E + +E + + + I+ T Q E+ Sbjct: 87 KKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRIL-TCQKTELQMA 145 Query: 1794 --FDHHTEEDIDKSANSVLI------KNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQM 1845 + H + ++ A ++ K + S+ K ++ T + Sbjct: 146 LYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDAL 205 Query: 1846 ESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPED 1905 + R+TI +E L+EK LQ + + + +S + N Sbjct: 206 SLELYRNTITDEELKEKNAK-----------LQEKLQLVESEKSEIQLNVKE-------- 246 Query: 1906 LMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELK 1965 L + + R K+ + ++ +A + + S S + + V+ N+ LW ++ ++++ Sbjct: 247 --LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE-LWNRLNQQQEEKMW 303 Query: 1966 AFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNC 2025 + + + K+ + K+ + ++ + + + + + E ++ +++ + Sbjct: 304 RQEEKIQEWEE------KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357 Query: 2026 LTEMETETKNLEDE--EKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQT 2083 + E E + + LE+ EK + E + +M EK EQ + +EE + E E ++EQ Sbjct: 358 MWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE--EKIREQEKRQEQE 415 Query: 2084 LAQIDFMQKQRNRTEELLDQ 2103 +K R + E++ +Q Sbjct: 416 AKMWRQEEKIREQEEKIREQ 435 Score = 36.6 bits (83), Expect = 0.29 Identities = 42/202 (20%), Positives = 90/202 (44%), Gaps = 9/202 (4%) Query: 1916 KIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIK 1975 KI+ E + +K+ + Q+K+ + + E+M +K + I+ K K Sbjct: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483 Query: 1976 SCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEM-ETETK 2034 + K+ + KV + + ++ EK++ + ++M + +KI ++ E E K Sbjct: 484 --MHEQEKIRKQEEKV---WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538 Query: 2035 NLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQR 2094 E EE EE E +E E+++ +EE+++ ++ QKE+ Q + + +Q Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598 Query: 2095 NR---TEELLDQLSLSEWDVVE 2113 + EE++ + W+ E Sbjct: 599 EKIREQEEMMQEQEEKMWEQEE 620 Score = 35.0 bits (79), Expect = 0.86 Identities = 42/234 (17%), Positives = 99/234 (42%), Gaps = 36/234 (15%) Query: 1916 KIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEK---------MRHCSDKELKA 1966 KIQ + E + + +KI E + Q++ + + +WEK M +++++ Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367 Query: 1967 FGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSA-----QNEREKLQIKIDEMDKILKK 2021 + + + ++ + Q K+ + Q Q +R++ + K+ ++ +++ Sbjct: 368 LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 427 Query: 2022 IDNCLTEMET----------ETKNLEDEEKNNPVEE-WDSEMRAAEK-----------EL 2059 + + E E E + + +EEK EE W E + E+ E Sbjct: 428 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487 Query: 2060 EQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVE 2113 E+++ +EE++ R ++ Q+E+ Q + M +Q + E +++ E + E Sbjct: 488 EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541 >gi|148839339 nexilin (F actin binding protein) [Homo sapiens] Length = 675 Score = 47.4 bits (111), Expect = 2e-04 Identities = 89/395 (22%), Positives = 162/395 (41%), Gaps = 46/395 (11%) Query: 1727 DSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSD 1786 + + E EEK I+ + + YE + ++ + V ++E + KK + K Sbjct: 190 EDLEKEREEKERIKYEEDKRIRYEEQRPSLKEAKCLSLVMDDEIESEAKKESLSPGKLKL 249 Query: 1787 TTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSI-----KADGTSLDFSTYR 1841 T ++ E +E+ K A K L + + + + T+ F YR Sbjct: 250 TFEELE---RQRQENRKKQAEEEARKRLEEEKRAFEEARRQMVNEDEENQDTAKIFKGYR 306 Query: 1842 SSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPP 1901 +++ F EE R++ +D + E + I +K + N V+ Sbjct: 307 PGKLKLSF------EEMERQRREDEKRKAEEE---ARRRIEEEKKAFAEARRNMVVDDDS 357 Query: 1902 TPEDLMLSQYVYRP-KIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHC- 1959 +SQ P K++I E E +QK+EE K + K +++ K +E++R Sbjct: 358 PEMYKTISQEFLTPGKLEINFE--ELLKQKMEEEKRRTEEERKHKLEMEKQEFEQLRQEM 415 Query: 1960 --SDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDK 2017 ++E + FG L++ K+ + + Q K L K + Q +++Q KI+E Sbjct: 416 GEEEEENETFG--LSREYEELIKLKRSGSIQAK-NLKSKFEKIGQLSEKEIQKKIEEERA 472 Query: 2018 ILKKIDNCLTEMETETKNLEDEEKNNPVEEWDS-------------EMRAAEKELEQLKT 2064 + ID + E E E + ED+ P + ++ +M A +E EQ + Sbjct: 473 RRRAIDLEIKEREAENFHEEDDVDVRPARKSEAPFTHKVNMKARFEQMAKAREEEEQRRI 532 Query: 2065 EEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEE 2099 EE++L R E Q+E A +QK+R EE Sbjct: 533 EEQKLLRMQFE---QREIDAA----LQKKREEEEE 560 >gi|21735548 centrosomal protein 2 [Homo sapiens] Length = 2442 Score = 47.0 bits (110), Expect = 2e-04 Identities = 43/205 (20%), Positives = 92/205 (44%), Gaps = 27/205 (13%) Query: 1912 VYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYL 1971 V R +I+ +D E +R +E L +D+++ + + + E A + Sbjct: 1505 VQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEE 1564 Query: 1972 NKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMET 2031 N K+ KL++ + +RE ++ + + L++ E++ Sbjct: 1565 N---------------HHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQ---ELQA 1606 Query: 2032 ETKNLEDEEKNNPV-----EEWDSEMRAAEKELEQLKTEEE----ELQRNLLELEVQKEQ 2082 ++ + D E ++ V +E D E+++ +++E+L+ ++E +L+R EL +QKE+ Sbjct: 1607 QSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKER 1666 Query: 2083 TLAQIDFMQKQRNRTEELLDQLSLS 2107 D +Q EE L+Q+ LS Sbjct: 1667 IQVLEDQRTRQTKILEEDLEQIKLS 1691 Score = 40.8 bits (94), Expect = 0.016 Identities = 26/104 (25%), Positives = 54/104 (51%), Gaps = 12/104 (11%) Query: 1998 VQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEK 2057 +++A+ R LQ+ + E +K + + T +E + + EE +E++A Sbjct: 633 MEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQK---------AEEAGAELQA--- 680 Query: 2058 ELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELL 2101 +L ++ E+EE+Q+ L E Q+E Q++ + ++ R EE+L Sbjct: 681 DLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVL 724 Score = 38.1 bits (87), Expect = 0.10 Identities = 33/124 (26%), Positives = 65/124 (52%), Gaps = 9/124 (7%) Query: 1988 QGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKN--NPV 2045 Q + AL L + A+ RE L K ++ L+K + E++ + +++++E++ + Sbjct: 638 QARNALQVDLAE-AEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKL 696 Query: 2046 EEWDSEMRAAEKELEQL----KTEEEELQRNLLELE-VQKEQTLAQIDFMQKQRNRTEEL 2100 E + AA +LEQL K +EE L R + E E + +E+ ++ +R+R ++L Sbjct: 697 SESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDR-QDL 755 Query: 2101 LDQL 2104 +QL Sbjct: 756 AEQL 759 Score = 37.0 bits (84), Expect = 0.23 Identities = 26/114 (22%), Positives = 56/114 (49%), Gaps = 5/114 (4%) Query: 2002 QNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEE--WDSEMRAAEKEL 2059 Q R+ L+ ++ ++++ L + +++ TE ++L+ + N E+ W+ + + E EL Sbjct: 1256 QQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESEL 1315 Query: 2060 EQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVE 2113 +L LQ L E+Q+ + + + +Q + E L Q+ + VVE Sbjct: 1316 MELHETMASLQSRLRRAELQRMEAQGERELLQAAK---ENLTAQVEHLQAAVVE 1366 Score = 33.5 bits (75), Expect = 2.5 Identities = 69/375 (18%), Positives = 150/375 (40%), Gaps = 87/375 (23%) Query: 1734 EEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREI 1793 E +A + Q+E + K+ ++ + Q+ Q E+ +H+E K R+ E+ + Q++E Sbjct: 677 ELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQ-LHQEAK-RQEEV-LARAVQEKEA 733 Query: 1794 FDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDT 1853 +K+A V ++ + R + L + + L+ S + + Q Sbjct: 734 LVR------EKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQ--------- 778 Query: 1854 ICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVY 1913 Q+ I + + + +Q+ + Q ++ V Sbjct: 779 ----------QNSVIEVTKGQLEVQIQTVTQ------------------------AKEVI 804 Query: 1914 RPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNK 1973 + +++ + + + R + E+ + +A+ Q K E+ + +KE+ N+ Sbjct: 805 QGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEV-------NQ 857 Query: 1974 IKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETET 2033 ++ + K HQ ++A K ++S + E+ +L++++ E TEME Sbjct: 858 LREKWEKERS--WHQQELA---KALESLEREKMELEMRLKEQQ----------TEMEAIQ 902 Query: 2034 KNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQ 2093 E+E AE L Q++ E E+ + +LLE +Q ++ LA Q + Sbjct: 903 AQREEERTQ------------AESALCQMQLETEKERVSLLETLLQTQKELADAS-QQLE 949 Query: 2094 RNRTEELLDQLSLSE 2108 R R + + +L E Sbjct: 950 RLRQDMKVQKLKEQE 964 Score = 32.7 bits (73), Expect = 4.3 Identities = 45/213 (21%), Positives = 85/213 (39%), Gaps = 35/213 (16%) Query: 1919 IYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCF 1978 + R+ + +++ + + S L D+ + L + S E K N ++S Sbjct: 1261 VLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQ-----NSLESEL 1315 Query: 1979 TKMTKVFTHQGKVALYGKLVQS------AQNEREKLQIKIDEMDKILKKIDNCLTEMETE 2032 ++ H+ +L +L ++ AQ ERE LQ + + ++ + + E + Sbjct: 1316 MEL-----HETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQ 1370 Query: 2033 TKN---LEDEE---------KNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLL------ 2074 LE++ KN VE +A +++ E + + LQ NL Sbjct: 1371 ASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTL 1430 Query: 2075 -ELEVQKEQTLAQIDFMQKQRNRTEELLDQLSL 2106 E E + E QI ++KQR + L+ LSL Sbjct: 1431 AEREEEVETLRGQIQELEKQREMQKAALELLSL 1463 Score = 32.0 bits (71), Expect = 7.3 Identities = 24/97 (24%), Positives = 47/97 (48%), Gaps = 2/97 (2%) Query: 2005 REKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKT 2064 R++LQ E D + + + E+++ +K E +K EE ++ E+E +L+ Sbjct: 434 RQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAR--EELRQQLEVLEQEAWRLRR 491 Query: 2065 EEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELL 2101 ELQ + QKE+ ++ ++R R +E+L Sbjct: 492 VNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEML 528 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 47.0 bits (110), Expect = 2e-04 Identities = 52/221 (23%), Positives = 106/221 (47%), Gaps = 24/221 (10%) Query: 1904 EDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLW---EKMRHCS 1960 ED M Q KI+ E + +K+ + QD+ + + + +W EK+R Sbjct: 345 EDKMWRQ---EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401 Query: 1961 DKELKAFGIYLNKIKSCFTKMTK----VFTHQGKVALYGKLVQSAQNE----REKLQI-- 2010 +K + K++ K+ + ++ + K+ +++Q + + EK+Q Sbjct: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461 Query: 2011 -KIDEMDKILKKIDNCLTEMETET----KNLEDEEKNNPVEE--WDSEMRAAEKELEQLK 2063 K+ E ++ +++ + + E E +T K L+ EEK EE W E + E+E E+++ Sbjct: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE-EKMQ 520 Query: 2064 TEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQL 2104 +EE++QR ++ Q+ + Q + MQ+Q R +EL ++L Sbjct: 521 EQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561 Score = 35.8 bits (81), Expect = 0.50 Identities = 67/373 (17%), Positives = 158/373 (42%), Gaps = 49/373 (13%) Query: 1768 EEDIHKEKKIRKNEIK-FSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLD 1826 E+ I EK + +E++ + + + R ++D+++S +S K + + + Sbjct: 55 EKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDE 114 Query: 1827 SIKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKP 1886 +I+ G S S +++S F + +EK+ + T R+ ++ + + + + Sbjct: 115 AIEDAGVS--HVKKNSDEVKSSF-------KKRQEKMNEKNYTFRKRVVIKKPWLRLGEV 165 Query: 1887 RQSNLPGNFTVN-TPPTPEDLMLSQYVYR-------PKIQIYR-----EDCEARRQKIEE 1933 P N + T + + Y+ + P +++YR E+ + + +++E Sbjct: 166 TAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQE 225 Query: 1934 LKLSASNQDKLLVDIN-KNLWEKMRHCS----DKELKAFGIYLNK-IKSCFTKMTKV--- 1984 KL +K + +N K+L K+ ++L+ L K ++S K+ Sbjct: 226 -KLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEE 284 Query: 1985 -----FTHQGKVALYGKLVQSAQNEREKL---QIKIDEMDKILKKIDNCLTEMETETKNL 2036 +Q + + + Q + EK+ ++KI E ++ + + + + E E + + Sbjct: 285 NELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ 344 Query: 2037 EDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNR 2096 ED + W E + E+E E+++ +EE++ R ++ Q E+ Q + M +Q + Sbjct: 345 ED-------KMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396 Query: 2097 TEELLDQLSLSEW 2109 E ++ W Sbjct: 397 IREQEEKRQEKMW 409 Score = 32.0 bits (71), Expect = 7.3 Identities = 25/111 (22%), Positives = 54/111 (48%), Gaps = 12/111 (10%) Query: 2005 REKLQIKIDEMDKILKKIDNCLTEM--ETETKNLEDEEKNNPVEEWDSEMRAAEKELEQL 2062 +++LQ++ D + K L+ + L E E NL ++++ + W E E++ Sbjct: 257 QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKM--WRQE--------EKI 306 Query: 2063 KTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVE 2113 + +EE++ L++ Q+E+ Q + M +Q + E D++ E + E Sbjct: 307 QEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE 357 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 47.0 bits (110), Expect = 2e-04 Identities = 52/221 (23%), Positives = 106/221 (47%), Gaps = 24/221 (10%) Query: 1904 EDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLW---EKMRHCS 1960 ED M Q KI+ E + +K+ + QD+ + + + +W EK+R Sbjct: 345 EDKMWRQ---EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401 Query: 1961 DKELKAFGIYLNKIKSCFTKMTK----VFTHQGKVALYGKLVQSAQNE----REKLQI-- 2010 +K + K++ K+ + ++ + K+ +++Q + + EK+Q Sbjct: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461 Query: 2011 -KIDEMDKILKKIDNCLTEMETET----KNLEDEEKNNPVEE--WDSEMRAAEKELEQLK 2063 K+ E ++ +++ + + E E +T K L+ EEK EE W E + E+E E+++ Sbjct: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE-EKMQ 520 Query: 2064 TEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQL 2104 +EE++QR ++ Q+ + Q + MQ+Q R +EL ++L Sbjct: 521 EQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561 Score = 35.8 bits (81), Expect = 0.50 Identities = 48/284 (16%), Positives = 119/284 (41%), Gaps = 32/284 (11%) Query: 1832 GTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNL 1891 GT ++ T + + R+TI +E L+EK + LQ + + + +S + Sbjct: 189 GTYIEKLTKERDALSLELYRNTITDEELKEKNAE-----------LQEKLRLVESEKSEI 237 Query: 1892 PGNFTVNTPPTPEDLMLSQYVY-RPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINK 1950 +N L +Q + + ++Q+ + Q + + +++L +N+ Sbjct: 238 Q----LNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293 Query: 1951 NLWEKMRHCSDKELKAFGIYLNKIKSCFTKMT------KVFTHQGKVALYGKLVQSAQNE 2004 EKM +K I + K C ++ K++ + K+ + ++ +++ Sbjct: 294 QQEEKMWRQEEK------IQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347 Query: 2005 REKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKT 2064 + + KI E ++ +++ + + E + + +++ + E W E + E+E + Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE----EK 403 Query: 2065 EEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSE 2108 +E++ R ++ Q E+ Q + M +Q + EL + + E Sbjct: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447 Score = 34.7 bits (78), Expect = 1.1 Identities = 25/114 (21%), Positives = 55/114 (48%), Gaps = 11/114 (9%) Query: 1999 QSAQNEREKL---QIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAA 2055 + Q + EK+ ++KI E ++ + + + + E E + + ED + W E + Sbjct: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQED-------KMWRQEEKIR 356 Query: 2056 EKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEW 2109 E+E E+++ +EE++ R ++ Q E+ Q + M +Q + E ++ W Sbjct: 357 EQE-EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409 Score = 32.0 bits (71), Expect = 7.3 Identities = 25/111 (22%), Positives = 54/111 (48%), Gaps = 12/111 (10%) Query: 2005 REKLQIKIDEMDKILKKIDNCLTEM--ETETKNLEDEEKNNPVEEWDSEMRAAEKELEQL 2062 +++LQ++ D + K L+ + L E E NL ++++ + W E E++ Sbjct: 257 QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKM--WRQE--------EKI 306 Query: 2063 KTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVE 2113 + +EE++ L++ Q+E+ Q + M +Q + E D++ E + E Sbjct: 307 QEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE 357 >gi|4758650 kinesin family member 5C [Homo sapiens] Length = 957 Score = 46.6 bits (109), Expect = 3e-04 Identities = 92/452 (20%), Positives = 199/452 (44%), Gaps = 59/452 (13%) Query: 1672 EQIPA-DTTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSIN 1730 EQI A D ++ + P+ I V ++ + +EE +Y + D IN Sbjct: 380 EQISAKDQKNLEPCDNTPIIDN---IAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEIN 436 Query: 1731 IETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEE-EDIHKEKKIRKNEIKFSDTTQ 1789 ++ L E ++++ + + T ++ +QEE + E + K+E+K + Q Sbjct: 437 ---QQSQLAEKLKQQMLDQDELLASTRRDYEK--IQEELTRLQIENEAAKDEVK--EVLQ 489 Query: 1790 DREI----FDHHTEEDIDKS-ANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQ 1844 E +D ++E DK+ AN L L++ ++ +++ + + R+++ Sbjct: 490 ALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATE 549 Query: 1845 MESQFLRDT-----ICEESLREKLQDGRITIREFFILLQVHI---------LIQKPRQ-- 1888 + + L+D I + + L D I E F + +++I L+ + +Q Sbjct: 550 ILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLE 609 Query: 1889 -SNLPGNFTVNTPPTPE---DLMLSQYVYRPK-IQIYREDCEARRQKIEELKLSASNQDK 1943 + + N +N L++SQ+ + K + Y ++ E +R+++EE +QD Sbjct: 610 SAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEE------SQDS 663 Query: 1944 LLVDINK-NLWEKMRHCS--DKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQS 2000 L ++ K EKM S DKE + +L +++ +M K Q + ++ Sbjct: 664 LSEELAKLRAQEKMHEVSFQDKEKE----HLTRLQDA-EEMKKALEQQMESHR-----EA 713 Query: 2001 AQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELE 2060 Q + +L+ +I+E KI+ +I + +++ E + L + +E+ + EM+ ++L Sbjct: 714 HQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKL--EKLL 771 Query: 2061 QLKTEEEELQRNLLELEVQKEQTLAQIDFMQK 2092 L + E+ + +L LE + L + ++K Sbjct: 772 LLNDKREQAREDLKGLEETVSRELQTLHNLRK 803 >gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] Length = 1780 Score = 46.2 bits (108), Expect = 4e-04 Identities = 55/290 (18%), Positives = 125/290 (43%), Gaps = 32/290 (11%) Query: 1908 LSQYVYRPKIQIYREDCEARRQKIE-----ELKLSASNQDKLLVDINKNLWEKMRHCSD- 1961 L+Q V K +I + QK+E +L+ ++ +++ + +NL E H D Sbjct: 1112 LTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDS 1171 Query: 1962 -KELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILK 2020 K K + K+K T++T K L K + N +E ++K +E+ Sbjct: 1172 VKNTKDLNVKELKLKEEITQLTNNLQDM-KHLLQLKEEEEETNRQETEKLK-EELSASSA 1229 Query: 2021 KIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQK 2080 + N +++ + ++ D ++ + + +++ +KE+ ++ E++ L+ + ELE +K Sbjct: 1230 RTQNLKADLQRKEEDYADLKEK--LTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKK 1287 Query: 2081 EQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVG 2140 Q ++D Q+ + +E L+ + E Y+ + +E ++ Sbjct: 1288 NQCSQELDMKQRTIQQLKEQLNNQKVEE------------AIQQYERACKDLNVKEKII- 1334 Query: 2141 FPFLDKRYRKIVDVNFQSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTC 2190 + R ++ Q+ +++DQ + L + + + E E WK+ C Sbjct: 1335 -----EDMRMTLEEQEQTQVEQDQVLEAKL---EEVERLATELEKWKEKC 1376 Score = 36.2 bits (82), Expect = 0.39 Identities = 74/396 (18%), Positives = 176/396 (44%), Gaps = 49/396 (12%) Query: 1734 EEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREI 1793 E + ++ET + E S + K+ + ++ ++ E ++ + ++ ++ +K T+D + Sbjct: 1125 ELETILETQKVECS-HSAKLEQDILEKESIILKLERNLKEFQEHLQDSVK---NTKDLNV 1180 Query: 1794 FDHHTEEDIDKSANSV-----LIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQ 1848 + +E+I + N++ L++ + + +K + L S+ R+ +++ Sbjct: 1181 KELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEE---LSASSARTQNLKAD 1237 Query: 1849 FLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLML 1908 R L+EKL D + I++ +Q + + + L +N Sbjct: 1238 LQRKEEDYADLKEKLTDAKKQIKQ----VQKEVSVMRDEDKLL--RIKINE--------- 1282 Query: 1909 SQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFG 1968 + + K Q +E + +++ I++LK +NQ + + + + R C D +K Sbjct: 1283 ---LEKKKNQCSQE-LDMKQRTIQQLKEQLNNQK-----VEEAIQQYERACKDLNVKEK- 1332 Query: 1969 IYLNKIKSCFTKMTKVFTHQGKVALYGKL--VQSAQNEREKLQIKIDEMDKILKKIDNCL 2026 + ++ + + Q +V L KL V+ E EK + K ++++ + N Sbjct: 1333 -IIEDMRMTLEEQEQTQVEQDQV-LEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKE 1390 Query: 2027 TEMETET----KNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQ 2082 E T+ NL+DE + + ++++++ + +E L T+ +E + N+ E++K Sbjct: 1391 HENNTDVLGKLTNLQDELQESE-QKYNADRKKWLEEKMMLITQAKEAE-NIRNKEMKKYA 1448 Query: 2083 TLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQ 2118 + F KQ+N E L QL+ + D+ +W +++ Sbjct: 1449 EDRERFF--KQQNEMEILTAQLTEKDSDLQKWREER 1482 Score = 32.7 bits (73), Expect = 4.3 Identities = 50/224 (22%), Positives = 98/224 (43%), Gaps = 26/224 (11%) Query: 1904 EDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKL-LVDINKNLWEKMRHCSDK 1962 E+L ++ + ++ ED + + +EE K S+++K L+D+ ++L +K+ + + Sbjct: 537 EELENAEETQNVETKLLDEDLD---KTLEENKAFISHEEKRKLLDLIEDLKKKLINEKKE 593 Query: 1963 ELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQI------KIDEMD 2016 +L ++ FT+ K L + +N +L I K D + Sbjct: 594 KLTLEFKIREEVTQEFTQYWAQREADFKETLLQEREILEENAERRLAIFKDLVGKCDTRE 653 Query: 2017 KILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKEL----EQLKTEEEELQRN 2072 + K I C T++ETE E K N ++ +E+ + EL E+LK E E Sbjct: 654 EAAKDI--CATKVETEEATACLELKFNQIK---AELAKTKGELIKTKEELKKRENESDSL 708 Query: 2073 LLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSD 2116 + ELE ++ + Q R +EL++ + E + E+ + Sbjct: 709 IQELETSNKKIIT-------QNQRIKELINIIDQKEDTINEFQN 745 >gi|87298937 centrosomal protein 110kDa [Homo sapiens] Length = 2325 Score = 46.2 bits (108), Expect = 4e-04 Identities = 83/392 (21%), Positives = 158/392 (40%), Gaps = 49/392 (12%) Query: 1765 VQEEEDIHKEKKIRKNE---IKFSDTTQDREIFD-HHTEEDI--DKSANSVLIKNLSRTP 1818 V EDI + K +K E ++ S ++E+ + HH +D+ +K + ++ L RT Sbjct: 1325 VSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTV 1384 Query: 1819 SSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICE-ESLREKLQDGRITIREFFILL 1877 D I DG T + + D + E E + + L R +RE LL Sbjct: 1385 QKRQQQKDFI--DGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLL 1442 Query: 1878 ---QVHILIQKPRQSNLPGNFT------VNTPPTPEDLMLSQYVYRPKIQIYREDCEARR 1928 + + K + N FT + T E+L + + + + D + R Sbjct: 1443 AEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEEL--ERRAQETAVNLVKADQQLRS 1500 Query: 1929 QKIE--ELKLSASNQDKLLVDINKNLWEKMR--HCSDKELKAFGIYLNKIKSCFTKMTKV 1984 + + +L+ Q+++L +INK + K C K+ + L K++ + Sbjct: 1501 LQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERN 1560 Query: 1985 FTHQGKVALYGK-LVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKN- 2042 H +V + L+Q+ + E EKL+ ++ + + +D L + E L+ Sbjct: 1561 EDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQA 1620 Query: 2043 ------------NPVEEWDSEMRAAEKELEQLKTEEEEL---------QRNLLELEVQKE 2081 V E + +R + LE+L ++ EL Q L++ E++KE Sbjct: 1621 KADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKE 1680 Query: 2082 QTLAQIDFMQKQRNRTE--ELLDQLSLSEWDV 2111 + Q+ Q +++TE +LD L L ++ Sbjct: 1681 EENLQVVLRQMSKHKTELKNILDMLQLENHEL 1712 Score = 37.4 bits (85), Expect = 0.17 Identities = 70/372 (18%), Positives = 147/372 (39%), Gaps = 56/372 (15%) Query: 1752 KMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLI 1811 ++G+T ++K ++E + + +E +K E+ + + ++ E + ++ V++ Sbjct: 1629 RLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVL 1688 Query: 1812 KNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIR 1871 + +S+ + + LD ++ + L + Q S+ + Sbjct: 1689 RQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKT------------------- 1729 Query: 1872 EFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKI 1931 QV +L +K NL ++ E Q + R K +I R E+R + Sbjct: 1730 ------QVAVLEEKLELENLQ---QISQQQKGEIEWQKQLLERDKREIERMTAESRALQS 1780 Query: 1932 EELKLSASNQDKLLVDINKNLWEK-------MRHCSDKELKAFGIYLNKIKSCFTKMTKV 1984 LS +D + ++WEK + +++ K L K++ K+ + Sbjct: 1781 CVECLSKEKED---LQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQE 1837 Query: 1985 FT--HQGKVALYGKLV---QSAQNEREKLQIKIDEMDKI-----LKKIDNCLTEMETETK 2034 ++ K++L+ + Q Q +RE + +E+ + L K D T + Sbjct: 1838 LDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVL 1897 Query: 2035 NLEDEEKNNPVEEWDSEMRAAEKELE----QLKTEEEELQRNLLELEVQKEQTLAQIDFM 2090 E + EW + +KE E QL+ + E++ N L+L VQ+E ++ Sbjct: 1898 LSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKL-VQQEMMFQRL--- 1953 Query: 2091 QKQRNRTEELLD 2102 QK+R E L+ Sbjct: 1954 QKERESEESKLE 1965 Score = 32.7 bits (73), Expect = 4.3 Identities = 72/382 (18%), Positives = 160/382 (41%), Gaps = 37/382 (9%) Query: 1721 DEINSSDSINIETEEKALIETYQ----KEISPYENKMGKTCNSQKRTWVQEEEDIHKEKK 1776 +EI + D +N +E+A+++ K +N++ K + Q++ ++ +E Sbjct: 298 EEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELTRACQKQYELEQELA 357 Query: 1777 IRKNEIKFSDTTQDREIFDHHTEE--DIDKSAN-------SVLIKNLSRTPSSCSSSLDS 1827 K + KF E +++ E +IDK+ + S +N+ T S S + Sbjct: 358 FYKIDAKF-------EPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATESYIIDSAQA 410 Query: 1828 IKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPR 1887 ++ D R+ M + T + L +K + +I+ + L ++H I+K Sbjct: 411 VQIKKMEPD-EQLRNDHMNLR--GHTPLDTQLEDK--EKKISAAQTR-LSELHDEIEKAE 464 Query: 1888 QSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVD 1947 Q L T E + L + K +Y++ R Q + +L+ A + + + Sbjct: 465 QQILRA--TEEFKQLEEAIQLKKISEAGKDLLYKQ-LSGRLQLVNKLRQEALDLELQMEK 521 Query: 1948 INKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREK 2007 + + K + D ++ + K K K Q ++ + K Q ++ ++ Sbjct: 522 QKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQ-QLDIMNKQYQQLESRLDE 580 Query: 2008 LQIKIDEMDKILKKIDNCLTEME---TETKNLEDEEKNNPVEEWDSEMRA----AEKELE 2060 + +I + + +K ++ LTE + E + E + ++E+ ++ A+ E Sbjct: 581 ILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECR 640 Query: 2061 QLKTEEEELQRNLLELEVQKEQ 2082 +L+ E+E L + L E+E +++Q Sbjct: 641 KLRDEKETLLQRLTEVEQERDQ 662 Score = 31.6 bits (70), Expect = 9.5 Identities = 27/127 (21%), Positives = 54/127 (42%), Gaps = 16/127 (12%) Query: 1997 LVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLED----------------EE 2040 ++Q +E + L+++ D+ L+K + E + E +NL+ E Sbjct: 1704 MLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLER 1763 Query: 2041 KNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEEL 2100 +E +E RA + +E L E+E+LQ E + QT + ++ + Sbjct: 1764 DKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSN 1823 Query: 2101 LDQLSLS 2107 L++L L+ Sbjct: 1824 LEKLELN 1830 >gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] Length = 1979 Score = 45.8 bits (107), Expect = 5e-04 Identities = 110/566 (19%), Positives = 227/566 (40%), Gaps = 85/566 (15%) Query: 1560 NLNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAHNDMHIVQATEIHNINIISSNAKDSR 1619 N NLN A Q H E L++L K DM I + + NI + ++ K+++ Sbjct: 748 NARNLNTS-----ALQLEH-----EHLIKLNQK--KDMEIAELKK--NIEQMDTDHKETK 793 Query: 1620 DEENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFLPRLPNKRNCSVTGIDDLEQIPADTT 1679 D + + T L K IF+ +L + + +D Q Sbjct: 794 DVLSSSLEEQKQLTQLINKKE-----------IFIEKLKERSSKLQEELDKYSQALRK-- 840 Query: 1680 DINHLETQPVSSKDSGIGSVAGKLNLSPSQY--INEENLPVYP-DEINSSDSINIETEEK 1736 N + Q + KD +GS+ + N + + EE P + + DS+ E Sbjct: 841 --NEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEV 898 Query: 1737 ALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDH 1796 + + T ++ + K Q ++ +Q + + ++KK +E ++ Q ++ Sbjct: 899 SQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKK-EMDEFRY----QHEQMNAT 953 Query: 1797 HTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICE 1856 HT+ ++K IK+L +T + L + D + + ++ ++++S + + + Sbjct: 954 HTQLFLEKDEE---IKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEK 1010 Query: 1857 ESLR----EKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYV 1912 L E+L G I RE L++ +L +K N+ ++ E L+Q + Sbjct: 1011 HDLSKAETERLVKG-IKERE----LEIKLLNEK----NISLTKQIDQLSKDEVGKLTQII 1061 Query: 1913 YRPKIQIY----REDCEARRQKI----EELKLSASNQDKLLVDINKNLWEKMRHCSDKEL 1964 + ++I R + Q + ++L+ A ++K+ +N+ E H + Sbjct: 1062 QQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENS-HLKTEYH 1120 Query: 1965 KAFGIY------LNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKI 2018 K I L K++ K++ F G+ ++ QN ++ K E+D + Sbjct: 1121 KMMDIVAAKEAALIKLQDENKKLSTRFESSGQ----DMFRETIQNLSRIIREKDIEIDAL 1176 Query: 2019 LKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEV 2078 +K L ++T + E N+ + E+L E ++L++ + ++E Sbjct: 1177 SQKCQTLLAVLQTSSTGNEAGGVNS-------------NQFEELLQERDKLKQQVKKMEE 1223 Query: 2079 QKEQTLAQIDFMQKQRNRTEELLDQL 2104 K+Q + + MQ + + +E L QL Sbjct: 1224 WKQQVMTTVQNMQHESAQLQEELHQL 1249 Score = 45.8 bits (107), Expect = 5e-04 Identities = 105/505 (20%), Positives = 205/505 (40%), Gaps = 93/505 (18%) Query: 1723 INSSDSINIETEEKALIETYQK----------EISPYENKMGKTCNSQKRTWVQEEEDIH 1772 ++S ++ ++ + LI++Y++ E++ ++ +G+ CN+ Sbjct: 1255 VDSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNT------------- 1301 Query: 1773 KEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADG 1832 K+ + K +I S + + E + S + VL S + L+ ++ Sbjct: 1302 KDLLLGKLDI-ISPQLSSASLLTPQSAECLRASKSEVL----SESSELLQQELEELRKSL 1356 Query: 1833 TSLDFSTYRSSQMESQFLRDTICEESLREKLQ----DGRIT-IREFFILLQVHI----LI 1883 D +T R+ Q + L D+I S E+ + D I ++E +LQ + L+ Sbjct: 1357 QEKD-ATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLL 1415 Query: 1884 QKPRQSNLPGNFTVNTPPTPEDLMLSQYV--YRPKIQIYREDC---EARRQKIEELKLSA 1938 K + L + T E+ +L Q V + +I I D + +KI E Sbjct: 1416 IKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLKGENEKIVETYRGK 1475 Query: 1939 SNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLV 1998 + + L + N +R K F + K K+ + QGK +L+ Sbjct: 1476 ETEYQALQETNMKFSMMLRE------KEFECHSMKEKALAFEQLLKEKEQGKTGELNQLL 1529 Query: 1999 QSAQNEREKLQIKIDEMDKIL-----KKIDNCLTEMETETKNLEDEE----------KNN 2043 + ++ +EK + E D+++ K+++N T ++ E + L D+E +N+ Sbjct: 1530 NAVKSMQEKTVVFQQERDQVMLALKQKQMEN--TALQNEVQRLRDKEFRSNQELERLRNH 1587 Query: 2044 PVEEWDSEMR---AAEKELEQLKTE----EEELQRNLLELEVQKEQTLAQIDFMQKQRN- 2095 +E DS R AAE +L+ + EE+L + +E Q Q++ +Q+Q N Sbjct: 1588 LLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLNV 1647 Query: 2096 ---RTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIV 2152 + +E QLS+S+ V +++ A V + Q EE + L+K+ + I Sbjct: 1648 VSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQ----EEKAMYSAELEKQKQLIA 1703 Query: 2153 D------------VNFQSLLDEDQA 2165 + ++ Q LDE A Sbjct: 1704 EWKKNAENLEGKVISLQECLDEANA 1728 Score = 38.1 bits (87), Expect = 0.10 Identities = 89/469 (18%), Positives = 191/469 (40%), Gaps = 72/469 (15%) Query: 1673 QIPADTTDINHLETQPVSSKD-------------SGIGSVAGKLNLSPSQYINEENLPVY 1719 Q+ +I+HL+ + ++ +D SG G A + S + I+ + Sbjct: 99 QLQQKEVEISHLKARQIALQDQLLKLQSAAQSVPSGAGVPATTASSSFAYGISHHPSAFH 158 Query: 1720 PDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIR- 1778 D+++ D I+ + E I E+S E+++G + + + Q ++ + + + Sbjct: 159 DDDMDFGDIISSQQE----INRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKL 214 Query: 1779 KNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFS 1838 +N IK + +EI DH E + ++A+ + +SR S + Sbjct: 215 QNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEE----------- 263 Query: 1839 TYRSSQMESQFLR--DTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPG--- 1893 R ++E+ + + E L K+ + + TI+ +LQ+ + + L Sbjct: 264 --RIEELENLLQQGGSGVIETDL-SKIYEMQKTIQ----VLQIEKVESTKKMEQLEDKIK 316 Query: 1894 --NFTVNTPPTPEDLML--SQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDIN 1949 N +++ D++ + + K QI E+CE + + +L+ SA Q + + Sbjct: 317 DINKKLSSAENDRDILRREQEQLNVEKRQIM-EECENLKLECSKLQPSAVKQSDTMTEKE 375 Query: 1950 KNLWEK---------MRHCSDKELKAFGIY-LNKIKSCFTKMTKVFTHQGKVALYGKLVQ 1999 + L + + SD E + + LN+ S K+ + ++ + K Sbjct: 376 RILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKL---KMRIEVLEKEKS 432 Query: 2000 SAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKEL 2059 E+E+LQ+ + +++ + I + T + L D N + A E+EL Sbjct: 433 LLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLN---------LEAKEQEL 483 Query: 2060 EQLKTEEEELQRNLLELEVQKEQTLAQI----DFMQKQRNRTEELLDQL 2104 Q +E+E L + EL+ Q ++ + D + KQ+N + ++ +L Sbjct: 484 NQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKL 532 Score = 35.0 bits (79), Expect = 0.86 Identities = 26/114 (22%), Positives = 61/114 (53%), Gaps = 2/114 (1%) Query: 2000 SAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKEL 2059 S Q E +L+ I + ++ L +I N L M++ ++ K+ ++E ++E+R ++ L Sbjct: 601 SIQKENLELKEHIRQNEEELSRIRNEL--MQSLNQDSNSNFKDTLLKEREAEVRNLKQNL 658 Query: 2060 EQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVE 2113 +L+ E L++ +++++ E+ + + ++ Q +QLSL + +VE Sbjct: 659 SELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVE 712 Score = 33.5 bits (75), Expect = 2.5 Identities = 59/291 (20%), Positives = 116/291 (39%), Gaps = 41/291 (14%) Query: 1925 EARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKS-----CFT 1979 E Q ++ + + N KL VD + ++ + +LK FG L +++ C T Sbjct: 1244 EELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQN--ETKLKNFGQELAQVQHSIGQLCNT 1301 Query: 1980 K---------------MTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDN 2024 K + T Q L + E LQ +++E+ K L++ D Sbjct: 1302 KDLLLGKLDIISPQLSSASLLTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDA 1361 Query: 2025 CLTEMETETKNLEDE-EKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLE----LEVQ 2079 + ++ L D + +E + E + E++QLK +++ LQ+ L E ++ + Sbjct: 1362 TIRTLQENNHRLSDSIAATSELERKEHEQ--TDSEIKQLKEKQDVLQKLLKEKDLLIKAK 1419 Query: 2080 KEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVV 2139 +Q L+ + + N E L ++ + + + D +L E+ V Sbjct: 1420 SDQLLSSNENFTNKVNENELLRQAVT---------NLKERILILEMDIGKLKGENEKIVE 1470 Query: 2140 GFPFLDKRYRKIVDVN--FQSLLDEDQAPPSSLLVHKLIF-QYVEEKESWK 2187 + + Y+ + + N F +L E + S+ L F Q ++EKE K Sbjct: 1471 TYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQLLKEKEQGK 1521 >gi|55770834 centromere protein F [Homo sapiens] Length = 3114 Score = 45.4 bits (106), Expect = 6e-04 Identities = 100/465 (21%), Positives = 184/465 (39%), Gaps = 86/465 (18%) Query: 1705 LSPSQYINEENLPVYPDEINSS--DSINIETEEKAL-----IETYQKEISPYENKMGKTC 1757 L+PSQY + ++ N + +E E KAL +T + + + Sbjct: 153 LTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQA 212 Query: 1758 NSQKRTWVQEEEDIHKEKKIRKNEIK--FSDT--TQDREIFDHHTEEDIDK-SANSVLIK 1812 +S +W QE+ H ++ I+ FS + + ++E+ + I K ANS Sbjct: 213 SSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSRSTLQIGKRDANSSFFD 272 Query: 1813 NLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLR----EKLQDGRI 1868 N SS LD +KA ++Q LR+ I E LR EK G++ Sbjct: 273 N-----SSSPHLLDQLKA---------------QNQELRNKINELELRLQGHEKEMKGQV 312 Query: 1869 TIREFFILLQVHI------LIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYRE 1922 F LQ+ + LI+K + N + V T + K++ E Sbjct: 313 NK---FQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTE 369 Query: 1923 DCEARRQKIEELKLSA---------------SNQDKLLVDINKNLWEKMRHCSDKELKAF 1967 D +RQ E + S S Q + +++ + + + +A Sbjct: 370 DLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAK 429 Query: 1968 GIYLNKIKSCFTKMTKVFTH--------QGKVALYGKLVQSAQNEREKLQIKIDEMDKIL 2019 ++ N +++ K+T V + K+ + Q++Q + +L+ ++EM K Sbjct: 430 NMH-NVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKEN 488 Query: 2020 KKIDNCLTEMETETKNLEDEEKN-----NPVEEWDSEMRAAEKELEQLKTEEEEL---QR 2071 + + + E +LE E KN N + + EM+A E + + +E Q Sbjct: 489 NLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQE 548 Query: 2072 NLLELE--------VQKEQTLAQIDFMQKQRNRTEELLDQLSLSE 2108 N L LE ++K++ +Q D ++K+ + E+L D+LS +E Sbjct: 549 NSLTLEKLKLAVADLEKQRDCSQ-DLLKKREHHIEQLNDKLSKTE 592 Score = 44.3 bits (103), Expect = 0.001 Identities = 143/723 (19%), Positives = 277/723 (38%), Gaps = 124/723 (17%) Query: 1600 VQATEIHNINIISSNAKDSRDEENK-----KSHNGAETTSLPPKTVFK--DKVRRCSLGI 1652 +Q ++ + +++ + +D+ N+ K H T P V + DK + L + Sbjct: 1645 LQGLDLSSRSLLGIDTEDAIQGRNESCDISKEHTSETTERTPKHDVHQICDKDAQQDLNL 1704 Query: 1653 FLPRLPNKRNCSVTGIDDLEQIPADTTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYIN 1712 + ++ TG EQ P + + SS+ S +G L P ++ Sbjct: 1705 DIEKITETGAVKPTGECSGEQSPDTNYEPPGEDKTQGSSECISELSFSGPNALVPMDFLG 1764 Query: 1713 EENLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKM----GKTCNSQKRTWVQEE 1768 + ++ ++ ++ N +IE +++ N+M K + + + E Sbjct: 1765 NQE-DIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIE 1823 Query: 1769 EDIHKEKKIRKNEIKFSDTTQDREIF--DHHT---------------EEDIDKSANSVLI 1811 I EK + + + + SD ++ E F DH E DKS+ + Sbjct: 1824 ACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIG 1883 Query: 1812 KNLSRTPSS-------CSSSLDSIKADGTSLDFST-YRSSQMESQFLRDTICEESLREKL 1863 N+++ S + L I+++ S++ Y + +E + +C E E Sbjct: 1884 DNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEV-VQTEKLCLEKDNENK 1942 Query: 1864 QDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRP--KIQIYR 1921 Q + + L+ + + ++ L G + T LS+ + +++ ++ Sbjct: 1943 Q-------KVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQ 1995 Query: 1922 EDC-------EAR-RQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGI---- 1969 +C EA ++K E L+ +S+ +LL D +L EK++ +K+ +A + Sbjct: 1996 SECLHCIQVAEAEVKEKTELLQTLSSDVSELLKD-KTHLQEKLQSL-EKDSQALSLTKCE 2053 Query: 1970 ------YLNKIKSCFTKMTKVFTHQGKVALYGKL-------------------VQSAQNE 2004 LNK K K ++ + + Y KL + S Q E Sbjct: 2054 LENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEE 2113 Query: 2005 R-------EKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSE------ 2051 EKL+++I+ +K I L E E E +L+D+ +N E SE Sbjct: 2114 VHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELV 2173 Query: 2052 ---MRAAEKELEQLKTEEEELQR-------NLLELEVQKEQTLAQIDFMQKQRNRTEELL 2101 ++ E+E LKT+ EE+ R +L+ L +KE QI Q Q + ++LL Sbjct: 2174 ILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLL 2233 Query: 2102 DQLS--LSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNFQSL 2159 L E + E + T V + +Q + V D+ K + + Sbjct: 2234 SSFKSLLEEKEQAEIQIKEESKTAV-EMLQNQLKELNEAVAALCGDQEIMKATEQSLDPP 2292 Query: 2160 LDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQLPKMLEEFSLVVHHCRLLGEEIEY 2219 ++E+ +S + KL + E + K+ C +L++ HH LL +E Sbjct: 2293 IEEEHQLRNS--IEKLRARL--EADEKKQLC--------VLQQLKESEHHADLLKGRVEN 2340 Query: 2220 LKR 2222 L+R Sbjct: 2341 LER 2343 Score = 41.6 bits (96), Expect = 0.009 Identities = 76/344 (22%), Positives = 153/344 (44%), Gaps = 51/344 (14%) Query: 1765 VQEEEDIHKEKKIRKNEI-KFSDTTQDRE-----IFDHHTEEDIDKSANSVLIKNLSRTP 1818 +QE ED ++ + + EI + + QD+E + E + K N L +NL+ Sbjct: 2507 IQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLEL-RNLTVEL 2565 Query: 1819 SSCSSSLDSIKA---DGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFI 1875 L S A D + S+Y++ + E + + + + S EK+ ++T +E + Sbjct: 2566 EQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTK--MDKMSFVEKVN--KMTAKETEL 2621 Query: 1876 LLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELK 1935 ++H + QK T E+L + ++Q+ E+ ++ + +++EL Sbjct: 2622 QREMHEMAQK-------------TAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELT 2668 Query: 1936 LSASNQDKLLVDINKNLWEK-------------MRHCSDKELKAFGIYLNKIKSCFTKMT 1982 L S K L ++K+ EK H ++K+ +A + NK Sbjct: 2669 LENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYE-----V 2723 Query: 1983 KVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEME-TETKNLE---D 2038 ++ T++ K+ + + S + E + L+ +E++ LK L E++ T+ NL+ Sbjct: 2724 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 2783 Query: 2039 EEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQ 2082 +K N E +M+ K +QL+ E+E LQ+ L +L+ +E+ Sbjct: 2784 LKKEN--ERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2825 Score = 34.7 bits (78), Expect = 1.1 Identities = 35/172 (20%), Positives = 75/172 (43%), Gaps = 19/172 (11%) Query: 1928 RQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTH 1987 R IE+L+ +K + + + L E H + ++++ ++ T+ Sbjct: 2300 RNSIEKLRARLEADEKKQLCVLQQLKESEHHAD--------LLKGRVENLERELEIARTN 2351 Query: 1988 QGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEE 2047 Q AL ++++ E E L+ KI+ M + L+ ++ + + +E +NL +E + +E Sbjct: 2352 QEHAALEA---ENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKE--QE 2406 Query: 2048 WDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEE 2099 SE+ E + E+E+ E KE++ ++ +Q Q E Sbjct: 2407 RISELEIINSSFENILQEKEQ------EKVQMKEKSSTAMEMLQTQLKELNE 2452 Score = 32.3 bits (72), Expect = 5.6 Identities = 52/237 (21%), Positives = 96/237 (40%), Gaps = 21/237 (8%) Query: 1883 IQKPRQSNLPGNFTVNTPPTPEDLML-----SQYV----YRPKIQIYREDCEARRQKIEE 1933 +++ +Q+ + ++N TP+ + SQY Y + Y ++ E R++ E Sbjct: 125 LERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAE 184 Query: 1934 LK-LSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMT-KVFTHQGKV 1991 +K L A + L N + RH + + F K S + + + + Sbjct: 185 VKALQAKKASQTLPQATMNHRDIARHQASSSV--FSWQQEKTPSHLSSNSQRTPIRRDFS 242 Query: 1992 ALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSE 2051 A Y Q R LQI + D DN + + +++E N + E + Sbjct: 243 ASYFSGEQEVTPSRSTLQI--GKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELR 300 Query: 2052 MRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRN---RTEELLDQLS 2105 ++ EKE++ + +ELQ L+LE K + + + + K R+ RT DQ S Sbjct: 301 LQGHEKEMKGQVNKFQELQ---LQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQAS 354 >gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] Length = 1417 Score = 45.4 bits (106), Expect = 6e-04 Identities = 68/293 (23%), Positives = 121/293 (41%), Gaps = 33/293 (11%) Query: 1829 KADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQ 1888 K G+S DF +M S +SLREKL ++ + ++ Q H L+ K Sbjct: 204 KISGSSTDFQKKPRDKMFSSSAPVDQEIKSLREKLN--KLRQQNACLVTQNHSLMTKFES 261 Query: 1889 SNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDI 1948 + F + ++ S + I E +I L+ S QDK+L + Sbjct: 262 IH----FELTQSRAKVSMLESAQQQAASVPILEE-------QIINLEAEVSAQDKVLREA 310 Query: 1949 NKNLWEKMRHCSDKE--LKAFGIYLNKIKSCF---TKMTKVFTHQGKVALYG--KLVQSA 2001 L + + +KE L+ K+K TK K Q ALY +L ++ Sbjct: 311 ENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAF 370 Query: 2002 QNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQ 2061 Q ++K+ K++++ + ++ LT E E K L++ + SE+ +++L Q Sbjct: 371 QQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQER-----CGLYKSELEILKEKLRQ 425 Query: 2062 LKTEEEELQRNLLELEVQKEQTLAQIDFMQKQ--------RNRTEELLDQLSL 2106 LK E + L + V+ + +AQ+ ++ N+ E L D+ SL Sbjct: 426 LKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSL 478 Score = 38.9 bits (89), Expect = 0.059 Identities = 101/466 (21%), Positives = 177/466 (37%), Gaps = 83/466 (17%) Query: 1684 LETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEKALIETYQ 1743 LE Q + K S+A K N Q + E+N + E N IN E E+ L Sbjct: 702 LEKQ-LEEKIVAYSSIAAK-NAELEQELMEKNEKIRSLETN----INTEHEKICLAFEKA 755 Query: 1744 KEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEEDID 1803 K+I ++K +K+ E + K+++ ++ E S QD HH E Sbjct: 756 KKIHLEQHK-----EMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLE---- 806 Query: 1804 KSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESL---- 1859 S + +L ++ +++KA + T + Q++S IC+E L Sbjct: 807 -SLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSAL---EICKEELVLHL 862 Query: 1860 ------REKLQDGRITIREFFILLQVHILIQKPR-QSNLPGNFTVNTPPTPEDLMLSQYV 1912 +EK + E LQ + I+ Q N + + ML Q Sbjct: 863 NQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQET 922 Query: 1913 YRP-KIQIYREDCEARRQKIEE--LKLSASNQDKLLVDINKNLWEKMRHCSD----KELK 1965 R +++ + E + K+E+ K S+ +KL K E H +D K ++ Sbjct: 923 IRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEK--CESAAHEADLKRQKVIE 980 Query: 1966 AFG------IYLNKIKSCFTKMTKVFTHQGK--------VALYGKLVQSAQNEREKLQIK 2011 G I +++ K +KM K H + ++ ++ + E EK Sbjct: 981 LTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNA 1040 Query: 2012 IDEMDKILKKIDNCLTE-------METETKN-----------------------LEDEEK 2041 + E++K+ + LTE +ETE +N L EEK Sbjct: 1041 VKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEK 1100 Query: 2042 NNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQI 2087 +++ +E+R + E+E K E E+ + L E + +Q AQ+ Sbjct: 1101 YTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQV 1146 Score = 38.5 bits (88), Expect = 0.078 Identities = 78/392 (19%), Positives = 164/392 (41%), Gaps = 27/392 (6%) Query: 1711 INEENLPVYPDEINSSDSINIETEEKALIETY--QKEISPYENKMGKTC--NSQKRTWVQ 1766 I +E L ++ +++ + + +K E Y QKE+ + + +T N + +Q Sbjct: 853 ICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQ 912 Query: 1767 EEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLD 1826 +++ + +++ IR E++ + T ++++ E + +++ ++ + S + D Sbjct: 913 QQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEAD 972 Query: 1827 SIKADGTSLDFSTYRSSQMESQFLRDTIC--EESLREKLQDGRITIREFFILLQVHILIQ 1884 + L T R ++E ++ + E+ + +DG + L Q+ +++ Sbjct: 973 LKRQKVIELT-GTARQVKIEMDQYKEELSKMEKEIMHLKRDGE---NKAMHLSQLDMILD 1028 Query: 1885 KPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIE-ELKLSASNQDK 1943 Q+ N E L S + RE E Q ELK + + Sbjct: 1029 ---QTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQE 1085 Query: 1944 LLVDINK---NLWEKMRHCSD--KELKAFGIYLNKIKSCFTKMTKVFTHQG-----KVAL 1993 L + K +L EK D EL+ + + K +M + + + A Sbjct: 1086 LRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQ 1145 Query: 1994 YGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKN--NPVEEWDSE 2051 L + + R +++ KI +++ L+K + L E + ++L D+ +N + E + Sbjct: 1146 VTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFI 1205 Query: 2052 MRAAEKELEQLKTEEEELQRNLLELE-VQKEQ 2082 M E+E+ QLK E E Q+ + E+E V KEQ Sbjct: 1206 MLQNEQEISQLKKEIERTQQRMKEMESVMKEQ 1237 Score = 33.9 bits (76), Expect = 1.9 Identities = 27/123 (21%), Positives = 60/123 (48%), Gaps = 11/123 (8%) Query: 1996 KLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLED-----EEKNNPVEEWDS 2050 KL Q Q +RE K+ +M++ K ++ E + + + + + + ++++ Sbjct: 941 KLEQELQKQRESSAEKLRKMEE---KCESAAHEADLKRQKVIELTGTARQVKIEMDQYKE 997 Query: 2051 EMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWD 2110 E+ EKE+ LK + E +L +L++ +QT + ++K+ N +EL +E + Sbjct: 998 ELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTE---LEKKTNAVKELEKLQHSTETE 1054 Query: 2111 VVE 2113 + E Sbjct: 1055 LTE 1057 Score = 32.7 bits (73), Expect = 4.3 Identities = 78/433 (18%), Positives = 184/433 (42%), Gaps = 46/433 (10%) Query: 1702 KLNLSPSQYINEENLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQK 1761 K+++ S ++P+ ++I IN+E E + K + ENK+ + SQK Sbjct: 272 KVSMLESAQQQAASVPILEEQI-----INLEAE----VSAQDKVLREAENKLEQ---SQK 319 Query: 1762 RTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSC 1821 +E+ +++ K ++ + T+ + + E + + L K + Sbjct: 320 MVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEE--LSKAFQQYKKKV 377 Query: 1822 SSSLDSIKADGTSLDFSTYRSSQMESQFLRDT---------ICEESLR---EKLQDGRIT 1869 + L+ ++A+ L+ + + E++ L++ I +E LR E+ +G+ Sbjct: 378 AEKLEKVQAEEEILE-RNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEK 436 Query: 1870 IREFFIL-LQVHILIQKPRQSNLPGNFTV-NTPPTPED---LMLSQYVYRPKIQIYREDC 1924 +R + +V + + RQS L + N D LM + ++ E Sbjct: 437 LRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERL 496 Query: 1925 EARRQKIEELKLSASNQDKLL--VDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMT 1982 + +Q+IE ++ + +K++ + + + L+ + S ++ +F ++ C + Sbjct: 497 DLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGC-CEAN 555 Query: 1983 KVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNC-----LTEMETETKNLE 2037 K+ + ++ L ++ A+ ++ + +++ + L ++ L+ +ETE L Sbjct: 556 KLVISELRIKL---AIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLG 612 Query: 2038 DEEKNNPVEEWDSEM--RAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQ-R 2094 + V++ + + EKE ++L T EEL+ L+++E + + Q + Sbjct: 613 GHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQ 672 Query: 2095 NRTEELLDQLSLS 2107 EELL++ S S Sbjct: 673 LIQEELLEKASNS 685 >gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo sapiens] Length = 805 Score = 45.4 bits (106), Expect = 6e-04 Identities = 72/361 (19%), Positives = 156/361 (43%), Gaps = 41/361 (11%) Query: 1766 QEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTE-EDIDKSANSVLIKNLS-RTPSSCSS 1823 Q+++ H ++IR NE++ + H+ ED ++ +N S +TP S S Sbjct: 381 QKQQITHLHERIRDNELR-----AQHAMLGHYVNCEDSYVASLQPQYENTSLQTPFSEES 435 Query: 1824 SLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILI 1883 S + + ST + ++FL+ + S +K + ++ R+ +I + Sbjct: 436 VSHSQQGEFEQKLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYIS-SLKKKC 494 Query: 1884 QKPRQSNLPGNFTVNTPPTPEDLMLSQYVYR-PKIQIYREDCEARRQKIEELKLSASNQD 1942 QK + N + T L +Y+ P + +D +++ +++ L+ N Sbjct: 495 QKESEQNKEKQRRIET--------LEKYLADLPTL----DDVQSQSLQLQILEEKNKNLQ 542 Query: 1943 KLLVDINKNLWEKMRHCSDKEL------KAFGIYLNKIKSCFTKMTKVFTHQGKVALYGK 1996 + L+D K L E + C DKE K + ++S K+ + ++ + Sbjct: 543 EALIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLD- 601 Query: 1997 LVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAE 2056 + QNE + L+ + + KI+ + + M E ++++ + E + Sbjct: 602 -AKQLQNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQG--------KLSKEKLTTQ 652 Query: 2057 KELEQLKTEEEELQR---NLLELEVQKEQTLAQIDFMQK-QRNRTEELLDQLSLSEWDVV 2112 K +E+L+ +E +QR LLE + Q ++T + +D Q+ ++R + +L + L + V+ Sbjct: 653 KMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTVLSKRPLFDLTVI 712 Query: 2113 E 2113 + Sbjct: 713 D 713 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 45.1 bits (105), Expect = 8e-04 Identities = 49/234 (20%), Positives = 103/234 (44%), Gaps = 22/234 (9%) Query: 1902 TPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDIN-KNLWEKMRHCS 1960 T E LS +YR I E+ + + K++E KL +K + +N K L K+ Sbjct: 260 TKERDALSLELYRNTIT--DEELKEKNAKLQE-KLQLVESEKSEIQLNVKELKRKLERAK 316 Query: 1961 ----DKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMD 2016 ++L+A +L K + + + + L+ +L Q + + + + KI E + Sbjct: 317 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE--LWNRLNQQQEEKMWRQEEKIQEWE 374 Query: 2017 KILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLEL 2076 + +++ + + E E + + E EEK EE E + E++ E+EE R E+ Sbjct: 375 EKIQEQEEKIREQEEKIR--EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 432 Query: 2077 EVQKEQTLAQID----------FMQKQRNRTEELLDQLSLSEWDVVEWSDDQAV 2120 +KE+ + +++ +++R E++ +Q E + W ++ + Sbjct: 433 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486 Score = 38.5 bits (88), Expect = 0.078 Identities = 50/208 (24%), Positives = 89/208 (42%), Gaps = 12/208 (5%) Query: 1916 KIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEK---MRHCSDKELKAFGIYLN 1972 KIQ + E + + +KI E + Q++ + + +WEK MR + + Sbjct: 369 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 428 Query: 1973 KIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETE 2032 + + + K K+ + K+ K+ + + +E+ +I+ E K+ + E Sbjct: 429 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE-----KRQEQEAKMWRQE 483 Query: 2033 TKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQID-FMQ 2091 K E EEK EE R EK EQ K EEE ++ E+ Q+E+ Q + + Q Sbjct: 484 EKIREQEEKIREQEE--KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541 Query: 2092 KQR-NRTEELLDQLSLSEWDVVEWSDDQ 2118 K++ + EE + + W E DQ Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQ 569 Score = 37.4 bits (85), Expect = 0.17 Identities = 78/381 (20%), Positives = 161/381 (42%), Gaps = 45/381 (11%) Query: 1732 ETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKF---SDTT 1788 E EEK I+ +++I E K+ + +R QEE KE+K+R+ E + Sbjct: 372 EWEEK--IQEQEEKIREQEEKIREQEEKMRR---QEEMMWEKEEKMRRQEEMMWEKEEKM 426 Query: 1789 QDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQ 1848 + +E EE I + + + R + I+ + Q E Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK- 485 Query: 1849 FLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLML 1908 +R+ EE +RE Q+ ++ +E I Q I ++ RQ E + Sbjct: 486 -IREQ--EEKIRE--QEEKMWRQEEKIHEQEKIREEEKRQEQ------EEMWRQEEKIRE 534 Query: 1909 SQYVYRPKIQIYREDCEARRQ--KIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKA 1966 + ++R K +I+ ++ + R+Q K+ + +Q++ + + + +W + ++E K Sbjct: 535 QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEK- 593 Query: 1967 FGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCL 2026 + + + + ++ Q + G+ + + EK+Q + ++M + +KI Sbjct: 594 ----IREQEEKIREQEEMTQEQEEKM--GEQEEKMCEQEEKMQEQEEKMRRQEEKI---- 643 Query: 2027 TEMETETKNLEDEEKNNPVEE---------WDSEMRAAEKELEQLKTEEEELQRNLLELE 2077 E E K E EEK EE W+ E + E+E E+++ +EE+++R ++ Sbjct: 644 --REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE-EKMQEQEEKMRRQEEKMW 700 Query: 2078 VQKEQTLAQIDFMQKQRNRTE 2098 Q+ + Q + MQ+ + E Sbjct: 701 EQEVRLRQQEEKMQEHQEHLE 721 Score = 37.4 bits (85), Expect = 0.17 Identities = 40/201 (19%), Positives = 93/201 (46%), Gaps = 11/201 (5%) Query: 1916 KIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIK 1975 KI+ E + +K+ + Q+K+ + + E+M +K + I+ K K Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 544 Query: 1976 ------SCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEM 2029 + K++ + K+ + ++ + + + + KI E ++ +++ + + E Sbjct: 545 IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQ 604 Query: 2030 ETETKNLEDEEKNNPVEE--WDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQI 2087 E T+ E EEK EE + E + E+E E+++ +EE+++ ++ Q+E+ Q Sbjct: 605 EEMTQ--EQEEKMGEQEEKMCEQEEKMQEQE-EKMRRQEEKIREQEKKIREQEEKIREQE 661 Query: 2088 DFMQKQRNRTEELLDQLSLSE 2108 + MQ+Q + E +++ E Sbjct: 662 EMMQEQEEKMWEQEEKMCEQE 682 Score = 34.7 bits (78), Expect = 1.1 Identities = 23/112 (20%), Positives = 57/112 (50%), Gaps = 1/112 (0%) Query: 2002 QNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQ 2061 Q E + + KI E ++ ++K + + E + + E++ + + W E + E+E E+ Sbjct: 535 QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE-EK 593 Query: 2062 LKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVE 2113 ++ +EE+++ + Q+E+ Q + M +Q + +E +++ E + E Sbjct: 594 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645 Score = 34.3 bits (77), Expect = 1.5 Identities = 31/203 (15%), Positives = 96/203 (47%), Gaps = 12/203 (5%) Query: 1912 VYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYL 1971 ++R + +I+ ++ +K +E + ++K+ + +W + ++E K Sbjct: 500 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ--EEIWRQKEKIHEQEEKI----R 553 Query: 1972 NKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMET 2031 + + + + K+ + K+ + V + + + + KI E ++ +++ + E E Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613 Query: 2032 ETKNLEDE--EKNNPVEEWDSEMRAAEKELEQ----LKTEEEELQRNLLELEVQKEQTLA 2085 + E++ E+ ++E + +MR E+++ + ++ +EE+++ ++ Q+E+ Sbjct: 614 KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673 Query: 2086 QIDFMQKQRNRTEELLDQLSLSE 2108 Q + M +Q + +E +++ E Sbjct: 674 QEEKMCEQEEKMQEQEEKMRRQE 696 Score = 33.9 bits (76), Expect = 1.9 Identities = 41/191 (21%), Positives = 85/191 (44%), Gaps = 6/191 (3%) Query: 1927 RRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFT 1986 + +KI EL+ Q+K+ K E+ +K + + + + K+ Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495 Query: 1987 HQGKVALYGKLVQSAQN--EREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNP 2044 + K+ + + + E EK Q + +EM + +KI + K E EEK Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQ-EEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554 Query: 2045 VEE--WDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLD 2102 EE W E + ++E E+++ +EE++ R ++ Q+E+ Q + +++Q T+E + Sbjct: 555 QEEKMWRQEEKMHDQE-EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613 Query: 2103 QLSLSEWDVVE 2113 ++ E + E Sbjct: 614 KMGEQEEKMCE 624 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.128 0.362 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 87,329,291 Number of Sequences: 37866 Number of extensions: 4033122 Number of successful extensions: 17118 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 110 Number of HSP's successfully gapped in prelim test: 549 Number of HSP's that attempted gapping in prelim test: 12584 Number of HSP's gapped (non-prelim): 3599 length of query: 2316 length of database: 18,247,518 effective HSP length: 118 effective length of query: 2198 effective length of database: 13,779,330 effective search space: 30286967340 effective search space used: 30286967340 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.