Search of human proteins with 71999143

Search of human proteins with 71999143

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71999143 opsin 4 isoform 2 [Homo sapiens]
         (489 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71999143 opsin 4 isoform 2 [Homo sapiens]                          999   0.0  
gi|15150803 opsin 4 isoform 1 [Homo sapiens]                          971   0.0  
gi|5730019 peropsin [Homo sapiens]                                    164   2e-40
gi|4506527 rhodopsin [Homo sapiens]                                   157   3e-38
gi|38678524 opsin 5 isoform 1 [Homo sapiens]                          152   7e-37
gi|71999131 opsin 3 [Homo sapiens]                                    149   6e-36
gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [H...   141   1e-33
gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo ...   141   1e-33
gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo sa...   137   2e-32
gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo s...   134   2e-31
gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]   124   3e-28
gi|149944554 somatostatin receptor 4 [Homo sapiens]                   114   2e-25
gi|157426873 tachykinin receptor 2 [Homo sapiens]                     108   1e-23
gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo s...   106   4e-23
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]          105   7e-23
gi|4557857 somatostatin receptor 1 [Homo sapiens]                     104   2e-22
gi|16751917 trace amine associated receptor 8 [Homo sapiens]          102   6e-22
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]   102   8e-22
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]   102   8e-22
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]    102   8e-22
gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo s...   102   1e-21
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                101   1e-21
gi|28173558 trace amine associated receptor 6 [Homo sapiens]          101   1e-21
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]         100   2e-21
gi|4557865 somatostatin receptor 5 [Homo sapiens]                     100   3e-21
gi|7669548 tachykinin receptor 3 [Homo sapiens]                       100   5e-21
gi|110618256 trace amine associated receptor 9 [Homo sapiens]         100   5e-21
gi|5174595 melatonin receptor 1B [Homo sapiens]                        99   9e-21
gi|32261309 G protein-coupled receptor 135 [Homo sapiens]              99   9e-21
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]           99   1e-20

>gi|71999143 opsin 4 isoform 2 [Homo sapiens]
          Length = 489

 Score =  999 bits (2583), Expect = 0.0
 Identities = 489/489 (100%), Positives = 489/489 (100%)

Query: 1   MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL 60
           MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
Sbjct: 1   MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL 60

Query: 61  PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFI 120
           PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFI
Sbjct: 61  PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFI 120

Query: 121 INLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRY 180
           INLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRY
Sbjct: 121 INLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRY 180

Query: 181 LVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT 240
           LVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT
Sbjct: 181 LVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT 240

Query: 241 PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQ 300
           PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQ
Sbjct: 241 PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQ 300

Query: 301 SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPII 360
           SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPII
Sbjct: 301 SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPII 360

Query: 361 YAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQ 420
           YAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQ
Sbjct: 361 YAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQ 420

Query: 421 ESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKG 480
           ESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKG
Sbjct: 421 ESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKG 480

Query: 481 LIPSQDPRM 489
           LIPSQDPRM
Sbjct: 481 LIPSQDPRM 489


>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
          Length = 478

 Score =  971 bits (2510), Expect = 0.0
 Identities = 478/489 (97%), Positives = 478/489 (97%), Gaps = 11/489 (2%)

Query: 1   MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL 60
           MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
Sbjct: 1   MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL 60

Query: 61  PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFI 120
           PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCR           SRSLRTPANMFI
Sbjct: 61  PTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCR-----------SRSLRTPANMFI 109

Query: 121 INLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRY 180
           INLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRY
Sbjct: 110 INLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRY 169

Query: 181 LVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT 240
           LVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT
Sbjct: 170 LVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT 229

Query: 241 PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQ 300
           PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQ
Sbjct: 230 PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQ 289

Query: 301 SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPII 360
           SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPII
Sbjct: 290 SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPII 349

Query: 361 YAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQ 420
           YAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQ
Sbjct: 350 YAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQ 409

Query: 421 ESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKG 480
           ESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKG
Sbjct: 410 ESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKG 469

Query: 481 LIPSQDPRM 489
           LIPSQDPRM
Sbjct: 470 LIPSQDPRM 478


>gi|5730019 peropsin [Homo sapiens]
          Length = 337

 Score =  164 bits (414), Expect = 2e-40
 Identities = 92/309 (29%), Positives = 156/309 (50%), Gaps = 22/309 (7%)

Query: 70  HYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFL 129
           H  + T +++ G+  ++ N+ V+  F           ++ + LRTP N  IINLAV+D  
Sbjct: 25  HNIVATYLIMAGMISIISNIIVLGIF-----------IKYKELRTPTNAIIINLAVTDIG 73

Query: 130 MSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLAT 189
           +S    P+   S LY  W FG  GC+ YA     FG++S+  LT +A+DRYL I  P   
Sbjct: 74  VSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVG 133

Query: 190 FGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTML 249
             + +      ++LG W+  L W+L P  GW++Y P+    +C+ ++     +  +YTM 
Sbjct: 134 RRMTTNTYIG-LILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMT 192

Query: 250 LCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIM 309
           +    F +PL ++ YCY  +  +I+       T   C  +    W  Q       + K+ 
Sbjct: 193 VIAINFIVPLTVMFYCYYHVTLSIKH-----HTTSDCTESLNRDWSDQ-----IDVTKMS 242

Query: 310 LLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYR 369
           +++I +F+++W+PYS V L A  G    + P M+ +  + AK+S  +NP IY + + K+R
Sbjct: 243 VIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFR 302

Query: 370 VAIAQHLPC 378
            A+     C
Sbjct: 303 RAMLAMFKC 311


>gi|4506527 rhodopsin [Homo sapiens]
          Length = 348

 Score =  157 bits (396), Expect = 3e-38
 Identities = 82/276 (29%), Positives = 147/276 (53%), Gaps = 15/276 (5%)

Query: 105 VMMQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALF 164
           V +Q + LRTP N  ++NLAV+D  M          +SL+  ++FG TGC    F   L 
Sbjct: 61  VTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLEGFFATLG 120

Query: 165 GISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYV 224
           G  ++ +L  +A++RY+V+ +P++ F    +  A   +   W+ ALA + PP  GWS Y+
Sbjct: 121 GEIALWSLVVLAIERYVVVCKPMSNFRFG-ENHAIMGVAFTWVMALACAAPPLAGWSRYI 179

Query: 225 PEGLLTSCSWDYMSFTPAVRAYTMLLCCFV--FFLPLLIIIYCYIFIFRAIRETGRALQT 282
           PEGL  SC  DY +  P V   + ++  FV  F +P++II +CY  +   ++E     Q 
Sbjct: 180 PEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQE 239

Query: 283 FGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYM 342
               +            ++E ++ ++++++++ F++ W PY++VA   F        P  
Sbjct: 240 SATTQ------------KAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGSNFGPIF 287

Query: 343 SSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPC 378
            ++PA  AK++AI+NP+IY + + ++R  +   + C
Sbjct: 288 MTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTICC 323


>gi|38678524 opsin 5 isoform 1 [Homo sapiens]
          Length = 354

 Score =  152 bits (384), Expect = 7e-37
 Identities = 92/303 (30%), Positives = 155/303 (51%), Gaps = 24/303 (7%)

Query: 69  AHYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDF 128
           A    G  + ++G+    GN  V+Y   R          + + LR PA +  INLAV D 
Sbjct: 32  ADLVAGFYLTIIGILSTFGNGYVLYMSSR----------RKKKLR-PAEIMTINLAVCDL 80

Query: 129 LMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLA 188
            +S    P    S    +W+FG  GC +Y + G  FG  S+IT+TA++LDRYL I     
Sbjct: 81  GISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKIC--YL 138

Query: 189 TFGVASKRRAAFV-LLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAV--RA 245
           ++GV  KR+ A++ L  +W YA  W+  P  G   YVPE   TSC+ D+     +V  + 
Sbjct: 139 SYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQV 198

Query: 246 YTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKM 305
           + + +  F   LP  +I++ Y+ I   ++ + + +  F +   +   L        E K+
Sbjct: 199 FILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVL--------EMKL 250

Query: 306 AKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITH 365
            K+ +L+   F+++W PY+ V++ +  G    +   +S VP ++AK++A++NPIIY +  
Sbjct: 251 TKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVID 310

Query: 366 PKY 368
            K+
Sbjct: 311 YKF 313


>gi|71999131 opsin 3 [Homo sapiens]
          Length = 402

 Score =  149 bits (376), Expect = 6e-36
 Identities = 100/339 (29%), Positives = 172/339 (50%), Gaps = 32/339 (9%)

Query: 51  GTWAAAWVPLPTVDVPDHAHYTLGT---VILLVGLTGMLG---NLTVIYTFCRAVLRGVT 104
           G  A A  P P   +     ++ GT   + LL+G  G+LG   NL V+  + +       
Sbjct: 16  GGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKF------ 69

Query: 105 VMMQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALF 164
                + LRTP ++ ++N+++SD L+S       F S L   W++   GC +  F G+LF
Sbjct: 70  -----QRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSLF 124

Query: 165 GISSMITLTAIALDRYL-VITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAY 223
           GI S+ TLT +A +RY+ V+   +  F  A +      +  +WLY+LAW+  P  GW+ Y
Sbjct: 125 GIVSIATLTVLAYERYIRVVHARVINFSWAWR-----AITYIWLYSLAWAGAPLLGWNRY 179

Query: 224 VPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTF 283
           + +     C+ D+ S      ++ + L      +PL +I +CY  I  +IR         
Sbjct: 180 ILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRML------- 232

Query: 284 GACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMS 343
             C  + +++   + L+ E K+AK+  L+I  F++ W PY  +  +   G+ H++TP +S
Sbjct: 233 -RCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTIS 291

Query: 344 SVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVL 382
            V  + AK++ ++NP+IY     K+R ++ Q L CL +L
Sbjct: 292 IVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQ-LLCLRLL 329


>gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [Homo
           sapiens]
          Length = 364

 Score =  141 bits (356), Expect = 1e-33
 Identities = 79/270 (29%), Positives = 139/270 (51%), Gaps = 15/270 (5%)

Query: 107 MQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGI 166
           M+ + LR P N  ++NLAV+D   +   + +   + +Y  ++ G   C    +  +L GI
Sbjct: 79  MKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCGI 138

Query: 167 SSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPE 226
           + + +L  I+ +R++V+ +P       +K     +    W++A  W+ PP FGWS Y P 
Sbjct: 139 TGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFS-WIWAAVWTAPPIFGWSRYWPH 197

Query: 227 GLLTSCSWDYMSFT--PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFG 284
           GL TSC  D  S +  P V++Y ++L       PL II+ CY+ ++ AIR          
Sbjct: 198 GLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIR---------A 248

Query: 285 ACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSS 344
             K   ES       ++E ++ +++++++L F   W PY+  A  A A   +   P M++
Sbjct: 249 VAKQQKES---ESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFHPLMAA 305

Query: 345 VPAVIAKASAIHNPIIYAITHPKYRVAIAQ 374
           +PA  AK++ I+NP+IY   + ++R  I Q
Sbjct: 306 LPAFFAKSATIYNPVIYVFMNRQFRNCILQ 335


>gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo
           sapiens]
          Length = 364

 Score =  141 bits (356), Expect = 1e-33
 Identities = 79/270 (29%), Positives = 139/270 (51%), Gaps = 15/270 (5%)

Query: 107 MQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGI 166
           M+ + LR P N  ++NLAV+D   +   + +   + +Y  ++ G   C    +  +L GI
Sbjct: 79  MKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHPMCVLEGYTVSLCGI 138

Query: 167 SSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPE 226
           + + +L  I+ +R++V+ +P       +K     +    W++A  W+ PP FGWS Y P 
Sbjct: 139 TGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFS-WIWAAVWTAPPIFGWSRYWPH 197

Query: 227 GLLTSCSWDYMSFT--PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFG 284
           GL TSC  D  S +  P V++Y ++L       PL II+ CY+ ++ AIR          
Sbjct: 198 GLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIR---------A 248

Query: 285 ACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSS 344
             K   ES       ++E ++ +++++++L F   W PY+  A  A A   +   P M++
Sbjct: 249 VAKQQKES---ESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFHPLMAA 305

Query: 345 VPAVIAKASAIHNPIIYAITHPKYRVAIAQ 374
           +PA  AK++ I+NP+IY   + ++R  I Q
Sbjct: 306 LPAFFAKSATIYNPVIYVFMNRQFRNCILQ 335


>gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo
           sapiens]
          Length = 364

 Score =  137 bits (346), Expect = 2e-32
 Identities = 77/270 (28%), Positives = 139/270 (51%), Gaps = 15/270 (5%)

Query: 107 MQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGI 166
           M+ + LR P N  ++NLAV+D   +   + +   + +   ++ G   C    +  +L GI
Sbjct: 79  MKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGI 138

Query: 167 SSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPE 226
           + + +L  I+ +R+LV+ +P       +K     +    W+++  W+ PP FGWS Y P 
Sbjct: 139 TGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFS-WIWSAVWTAPPIFGWSRYWPH 197

Query: 227 GLLTSCSWDYMSFT--PAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFG 284
           GL TSC  D  S +  P V++Y ++L      +PL II+ CY+ ++ AIR          
Sbjct: 198 GLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIR---------A 248

Query: 285 ACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSS 344
             K   ES       ++E ++ ++++++I  + + W PY+  A  A A   +   P M++
Sbjct: 249 VAKQQKES---ESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAA 305

Query: 345 VPAVIAKASAIHNPIIYAITHPKYRVAIAQ 374
           +PA  AK++ I+NP+IY   + ++R  I Q
Sbjct: 306 LPAYFAKSATIYNPVIYVFMNRQFRNCILQ 335


>gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo
           sapiens]
          Length = 348

 Score =  134 bits (336), Expect = 2e-31
 Identities = 74/268 (27%), Positives = 137/268 (51%), Gaps = 15/268 (5%)

Query: 107 MQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGI 166
           ++ + LR P N  ++N++   FL+        F +S    ++FG   C    F G + G+
Sbjct: 60  LRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFVFGRHVCALEGFLGTVAGL 119

Query: 167 SSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPE 226
            +  +L  +A +RY+VI +P   F  +SK  A  V+L  W   +  S+PPFFGWS ++PE
Sbjct: 120 VTGWSLAFLAFERYIVICKPFGNFRFSSKH-ALTVVLATWTIGIGVSIPPFFGWSRFIPE 178

Query: 227 GLLTSCSWDYMSFTPAVR--AYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFG 284
           GL  SC  D+ +     R  +YT  L  F F +PL +I + Y  + RA++      Q   
Sbjct: 179 GLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESA 238

Query: 285 ACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSS 344
             +            ++E ++++++++++  F + + PY+A A+       H L   + +
Sbjct: 239 TTQ------------KAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGLDLRLVT 286

Query: 345 VPAVIAKASAIHNPIIYAITHPKYRVAI 372
           +P+  +K++ I+NPIIY   + +++  I
Sbjct: 287 IPSFFSKSACIYNPIIYCFMNKQFQACI 314


>gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]
          Length = 529

 Score =  124 bits (310), Expect = 3e-28
 Identities = 97/349 (27%), Positives = 161/349 (46%), Gaps = 49/349 (14%)

Query: 77  ILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQAP 136
           I+++ +   LGNL ++ T           + +   L T +N F+ +L +S+FL+S    P
Sbjct: 34  IIVITIFVCLGNLVIVVT-----------LYKKSYLLTLSNKFVFSLTLSNFLLSVLVLP 82

Query: 137 VFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKR 196
              TSS+ ++W+FG   C F A    L   +SM+TL  IA+DRY  +  P+      +  
Sbjct: 83  FVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGN 142

Query: 197 RAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSC--SWDYMSFTPAVRAYTMLLCCFV 254
           RA   L+ +WL++L   LPP FGWS+   +     C  +W      P   A+  + C   
Sbjct: 143 RAVMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHR---EPGYTAFWQIWCA-- 197

Query: 255 FFLPLLIIIYCYIFIFRAIR-------------------ETGRA-LQTFGACKGNGESLW 294
              P L+++ CY FIFR  R                    TGR    T  +  G+  + +
Sbjct: 198 -LFPFLVMLVCYGFIFRVARVKARKVHCGTVVIVEEDAQRTGRKNSSTSTSSSGSRRNAF 256

Query: 295 QRQRLQ-SECKMAKIMLLVILLFVLSWAPYSAV-ALVAFAGYAHVLTPYMSSVPAVIAKA 352
           Q      ++CK    +L+V+  F+++W PY  V A  A  G + V +P + +    ++ A
Sbjct: 257 QGVVYSANQCKALITILVVLGAFMVTWGPYMVVIASEALWGKSSV-SPSLETWATWLSFA 315

Query: 353 SAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHR 401
           SA+ +P+IY + +   R  +      LG+  G  R +  P+   + T R
Sbjct: 316 SAVCHPLIYGLWNKTVRKEL------LGMCFG-DRYYREPFVQRQRTSR 357


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score =  114 bits (286), Expect = 2e-25
 Identities = 90/332 (27%), Positives = 154/332 (46%), Gaps = 36/332 (10%)

Query: 76  VILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQA 135
           +  LV L G++GN  VI+           V+++   ++T  N++++NLAV+D L   +  
Sbjct: 53  IYALVCLVGLVGNALVIF-----------VILRYAKMKTATNIYLLNLAVADELFMLS-V 100

Query: 136 PVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASK 195
           P   +S+  + W FG   C        L   +S+  LT +++DRY+ +  PL        
Sbjct: 101 PFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRP 160

Query: 196 RRAAFVLLGVWLYALAWSLP-PFFGWSAYVPEGLLTSCS--WDYMSFTPAVRAYTMLLCC 252
             A  + LGVWL +L  +LP   F  +     G   +C+  W + +++     YT LL  
Sbjct: 161 SVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLL-- 218

Query: 253 FVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLV 312
             F LP+L I  CY+ I   +R                 + WQ QR +SE K+ +++L+V
Sbjct: 219 -GFLLPVLAIGLCYLLIVGKMRAVAL------------RAGWQ-QRRRSEKKITRLVLMV 264

Query: 313 ILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAI 372
           +++FVL W P+  V L+    +   L   ++ V  +++ A++  NPI+Y      +R   
Sbjct: 265 VVVFVLCWMPFYVVQLLNL--FVTSLDATVNHVSLILSYANSCANPILYGFLSDNFR-RF 321

Query: 373 AQHLPCLG--VLLGVSRRHSRPYPSYRSTHRS 402
            Q + CL   +L G       P   Y +  +S
Sbjct: 322 FQRVLCLRCCLLEGAGGAEEEPLDYYATALKS 353


>gi|157426873 tachykinin receptor 2 [Homo sapiens]
          Length = 398

 Score =  108 bits (269), Expect = 1e-23
 Identities = 84/301 (27%), Positives = 133/301 (44%), Gaps = 29/301 (9%)

Query: 75  TVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQ 134
           T  L + L  + GN  VI+           +++  R +RT  N FI+NLA++D  M+   
Sbjct: 38  TAYLALVLVAVTGNAIVIW-----------IILAHRRMRTVTNYFIVNLALADLCMAAFN 86

Query: 135 APVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVAS 194
           A   F  + +  W FG   C F           S+ ++TAIA DRY+ I  P      A 
Sbjct: 87  AAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAP 146

Query: 195 KRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSC--SWDYMSFTPAVRAYTMLLCC 252
             +A  V+ G+WL ALA + P  F  +  + +G  T C  +W   S    +  Y +++  
Sbjct: 147 STKA--VIAGIWLVALALASPQCFYSTVTMDQG-ATKCVVAWPEDSGGKTLLLYHLVVIA 203

Query: 253 FVFFLPLLIIIYCYIFIFRAI-RETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLL 311
            ++FLPL ++   Y  I   + R      Q  GA           + LQ+  K  K M+L
Sbjct: 204 LIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGA---------NLRHLQAMKKFVKTMVL 254

Query: 312 VILLFVLSWAPYSAVALVAFAG---YAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKY 368
           V+L F + W PY    ++       Y H     +      +A +S ++NPIIY   + ++
Sbjct: 255 VVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRF 314

Query: 369 R 369
           R
Sbjct: 315 R 315


>gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo
           sapiens]
          Length = 291

 Score =  106 bits (265), Expect = 4e-23
 Identities = 81/291 (27%), Positives = 131/291 (45%), Gaps = 42/291 (14%)

Query: 73  LGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSF 132
           +G V+L+  L+G+  N   I++FC+           +  LRTP ++ +++LA++D  +S 
Sbjct: 19  VGMVLLVEALSGLSLNTLTIFSFCK-----------TPELRTPCHLLVLSLALADSGISL 67

Query: 133 TQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGV 192
             A V  TSSL ++W +G  GC+ + F G +  ++S+ +  AIA  RY        T   
Sbjct: 68  N-ALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY----HHYCTRSQ 122

Query: 193 ASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCC 252
            +   A  ++L VWL +  W+  P  GW  Y  E L T C+ DY        ++   +  
Sbjct: 123 LAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSF 182

Query: 253 FVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLV 312
           F F +PL I I  Y  + + + ++G                     LQ    +    LL 
Sbjct: 183 FNFAMPLFITITSYSLMEQKLGKSG--------------------HLQVNTTLPARTLL- 221

Query: 313 ILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAI 363
                L W PY+ + L A       ++P +  VPA+IAK     N I YA+
Sbjct: 222 -----LGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYAL 267


>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
          Length = 407

 Score =  105 bits (263), Expect = 7e-23
 Identities = 71/305 (23%), Positives = 147/305 (48%), Gaps = 28/305 (9%)

Query: 79  LVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQAPVF 138
           ++ +T ++GN+ V++           +++  + +RT  N F++NLA ++  M+     V 
Sbjct: 41  VIVVTSVVGNVVVMW-----------IILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVN 89

Query: 139 FTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRA 198
           FT +++ +W +G   C+F+ F       +S+ ++TA+A DRY+ I  PL     A+  + 
Sbjct: 90  FTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKV 149

Query: 199 AFVLLGVWLYALAWSLPP-FFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFL 257
             V+  +W+ AL  + P  ++  +  +P  ++    W         + Y + +   ++FL
Sbjct: 150 --VICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFL 207

Query: 258 PLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQ-RQRLQSECKMAKIMLLVILLF 316
           PLL+I Y Y  +            T  A +  G+S  +  +++ ++ K+ K+M++V+  F
Sbjct: 208 PLLVIGYAYTVVG----------ITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTF 257

Query: 317 VLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVI---AKASAIHNPIIYAITHPKYRVAIA 373
            + W P+    L+ +      L  ++  V   I   A +S ++NPIIY   + ++R+   
Sbjct: 258 AICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFK 317

Query: 374 QHLPC 378
               C
Sbjct: 318 HAFRC 322


>gi|4557857 somatostatin receptor 1 [Homo sapiens]
          Length = 391

 Score =  104 bits (260), Expect = 2e-22
 Identities = 95/374 (25%), Positives = 165/374 (44%), Gaps = 40/374 (10%)

Query: 10  PPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPLPTVDVPDHA 69
           P      PS   +P+P S  +   S     G    +    PG  A+      T+     +
Sbjct: 3   PNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEE--PGRNASQ---NGTLSEGQGS 57

Query: 70  HYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFL 129
              +  +  +V L G+ GN  VIY           V+++   ++T  N++I+NLA++D L
Sbjct: 58  AILISFIYSVVCLVGLCGNSMVIY-----------VILRYAKMKTATNIYILNLAIADEL 106

Query: 130 MSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLAT 189
           +  +  P   TS+L + W FG   C       A+   +S+  LT +++DRY+ +  P+  
Sbjct: 107 LMLS-VPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKA 165

Query: 190 FGVASKRRAAFVLLGVWLYALAWSLP-PFFGWSAYVPEGLLTSCSWDYMSFTPAVR---A 245
                   A  V LGVW+ +L   LP   F  +A   +G   + + + +   PA R    
Sbjct: 166 ARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDG---TVACNMLMPEPAQRWLVG 222

Query: 246 YTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKM 305
           + +      F LP+  I  CY+ I   +R          A K      WQ QR +SE K+
Sbjct: 223 FVLYTFLMGFLLPVGAICLCYVLIIAKMRMV--------ALKAG----WQ-QRKRSERKI 269

Query: 306 AKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITH 365
             ++++V+++FV+ W P+  V LV    +A      +S +  ++  A++  NPI+Y    
Sbjct: 270 TLMVMMVVMVFVICWMPFYVVQLVNV--FAEQDDATVSQLSVILGYANSCANPILYGFLS 327

Query: 366 PKYRVAIAQHLPCL 379
             ++ +  Q + CL
Sbjct: 328 DNFKRSF-QRILCL 340


>gi|16751917 trace amine associated receptor 8 [Homo sapiens]
          Length = 342

 Score =  102 bits (255), Expect = 6e-22
 Identities = 83/304 (27%), Positives = 140/304 (46%), Gaps = 20/304 (6%)

Query: 73  LGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSF 132
           L T      L  + GNL V+           T ++  + L +P N  I +LA +DFL+  
Sbjct: 34  LYTAFSFGSLLAVFGNLLVM-----------TSVLHFKQLHSPTNFLIASLACADFLVGV 82

Query: 133 TQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGV 192
           T        ++   W FG   C  ++ C   F  SS++ L  I +DRY+V+T PL     
Sbjct: 83  TVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATK 142

Query: 193 ASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGL--LTSCSWDYMSFTPAVRAYTMLL 250
            +   +   +   W+  L +S   F+  +    +GL  L S           V    +L+
Sbjct: 143 FTVSVSGICISVSWILPLTYSGAVFY--TGVNDDGLEELVSALNCVGGCQIIVSQGWVLI 200

Query: 251 CCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIML 310
              +FF+P L++I  Y  IF   ++    ++T  +   +    ++ +  + E K AK + 
Sbjct: 201 DFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLG 260

Query: 311 LVILLFVLSWAPYSAVALV-AFAGYAHVLTP-YMSSVPAVIAKASAIHNPIIYAITHPKY 368
           + +L FV+SW PY+   L+ AF G+   LTP Y+  +    A  ++  NP+IYA+ +P +
Sbjct: 261 VTVLAFVISWLPYTVDILIDAFMGF---LTPAYIYEICCWSAYYNSAMNPLIYALFYPWF 317

Query: 369 RVAI 372
           R AI
Sbjct: 318 RKAI 321


>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
          Length = 432

 Score =  102 bits (254), Expect = 8e-22
 Identities = 98/401 (24%), Positives = 171/401 (42%), Gaps = 78/401 (19%)

Query: 36  ISSLGR-LPSISPTA-----PGTWAAAWV------PLPTVDVP--------DHAHY---- 71
           +  +GR LP +SP        G+WA   +      P PT D P        +  +Y    
Sbjct: 21  LPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVE 80

Query: 72  --TLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFL 129
              +G+++ L+ L  + GN  V+ + C             + LR P+N  I++LA++D  
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFV-----------KKLRQPSNYLIVSLALADLS 129

Query: 130 MSFTQAP-VFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLA 188
           ++    P V  T  +  +W+FG   C  +     +   +S++TL  I++DRYL ITRPL 
Sbjct: 130 VAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPL- 188

Query: 189 TFGVASKRRA-AFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYT 247
           T+ V    +  A ++L VWL + + +LPP FGW+  V +  +   S D+         YT
Sbjct: 189 TYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDF--------GYT 240

Query: 248 MLLCCFVFFLPLLIIIYCYIFIFRAIR--------------ETGRALQTFGACK------ 287
           +      F++P+ ++++ Y  I++A R              E    +   G  K      
Sbjct: 241 IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE 300

Query: 288 --GNGESLWQRQR-----LQSECKMAKIMLLVILLFVLSWAPY--SAVALVAFAGYAHVL 338
              N   L + +R      + E K A  + +++  F + W P+   + A     G +   
Sbjct: 301 ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC 360

Query: 339 TP-YMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPC 378
            P ++      +  A+++ NP IYA  +   R      L C
Sbjct: 361 IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQC 401


>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
          Length = 479

 Score =  102 bits (254), Expect = 8e-22
 Identities = 98/401 (24%), Positives = 171/401 (42%), Gaps = 78/401 (19%)

Query: 36  ISSLGR-LPSISPTA-----PGTWAAAWV------PLPTVDVP--------DHAHY---- 71
           +  +GR LP +SP        G+WA   +      P PT D P        +  +Y    
Sbjct: 21  LPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVE 80

Query: 72  --TLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFL 129
              +G+++ L+ L  + GN  V+ + C             + LR P+N  I++LA++D  
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFV-----------KKLRQPSNYLIVSLALADLS 129

Query: 130 MSFTQAP-VFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLA 188
           ++    P V  T  +  +W+FG   C  +     +   +S++TL  I++DRYL ITRPL 
Sbjct: 130 VAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPL- 188

Query: 189 TFGVASKRRA-AFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYT 247
           T+ V    +  A ++L VWL + + +LPP FGW+  V +  +   S D+         YT
Sbjct: 189 TYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDF--------GYT 240

Query: 248 MLLCCFVFFLPLLIIIYCYIFIFRAIR--------------ETGRALQTFGACK------ 287
           +      F++P+ ++++ Y  I++A R              E    +   G  K      
Sbjct: 241 IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE 300

Query: 288 --GNGESLWQRQR-----LQSECKMAKIMLLVILLFVLSWAPY--SAVALVAFAGYAHVL 338
              N   L + +R      + E K A  + +++  F + W P+   + A     G +   
Sbjct: 301 ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC 360

Query: 339 TP-YMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPC 378
            P ++      +  A+++ NP IYA  +   R      L C
Sbjct: 361 IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQC 401


>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
          Length = 445

 Score =  102 bits (254), Expect = 8e-22
 Identities = 98/401 (24%), Positives = 171/401 (42%), Gaps = 78/401 (19%)

Query: 36  ISSLGR-LPSISPTA-----PGTWAAAWV------PLPTVDVP--------DHAHY---- 71
           +  +GR LP +SP        G+WA   +      P PT D P        +  +Y    
Sbjct: 21  LPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVE 80

Query: 72  --TLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFL 129
              +G+++ L+ L  + GN  V+ + C             + LR P+N  I++LA++D  
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFV-----------KKLRQPSNYLIVSLALADLS 129

Query: 130 MSFTQAP-VFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLA 188
           ++    P V  T  +  +W+FG   C  +     +   +S++TL  I++DRYL ITRPL 
Sbjct: 130 VAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPL- 188

Query: 189 TFGVASKRRA-AFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYT 247
           T+ V    +  A ++L VWL + + +LPP FGW+  V +  +   S D+         YT
Sbjct: 189 TYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDF--------GYT 240

Query: 248 MLLCCFVFFLPLLIIIYCYIFIFRAIR--------------ETGRALQTFGACK------ 287
           +      F++P+ ++++ Y  I++A R              E    +   G  K      
Sbjct: 241 IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE 300

Query: 288 --GNGESLWQRQR-----LQSECKMAKIMLLVILLFVLSWAPY--SAVALVAFAGYAHVL 338
              N   L + +R      + E K A  + +++  F + W P+   + A     G +   
Sbjct: 301 ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC 360

Query: 339 TP-YMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPC 378
            P ++      +  A+++ NP IYA  +   R      L C
Sbjct: 361 IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQC 401


>gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo
           sapiens]
          Length = 295

 Score =  102 bits (253), Expect = 1e-21
 Identities = 81/295 (27%), Positives = 132/295 (44%), Gaps = 46/295 (15%)

Query: 73  LGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSF 132
           +G V+L+  L+G+  N   I++FC+           +  LRTP ++ +++LA++D  +S 
Sbjct: 19  VGMVLLVEALSGLSLNTLTIFSFCK-----------TPELRTPCHLLVLSLALADSGISL 67

Query: 133 TQAPVFFTSSL----YKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLA 188
             A V  TSSL    +++W +G  GC+ + F G +  ++S+ +  AIA  RY        
Sbjct: 68  N-ALVAATSSLLRVSHRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRY----HHYC 122

Query: 189 TFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTM 248
           T    +   A  ++L VWL +  W+  P  GW  Y  E L T C+ DY        ++  
Sbjct: 123 TRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLF 182

Query: 249 LLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKI 308
            +  F F +PL I I  Y  + + + ++G                     LQ    +   
Sbjct: 183 TMSFFNFAMPLFITITSYSLMEQKLGKSG--------------------HLQVNTTLPAR 222

Query: 309 MLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAI 363
            LL      L W PY+ + L A       ++P +  VPA+IAK     N I YA+
Sbjct: 223 TLL------LGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYAL 271


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score =  101 bits (252), Expect = 1e-21
 Identities = 94/401 (23%), Positives = 167/401 (41%), Gaps = 64/401 (15%)

Query: 22  TPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVG 81
           T AP  W +   ++ +   +  S S             LP +D+      ++G V+    
Sbjct: 11  TSAPAHWGELKNANFTGPNQTSSNST------------LPQLDIT--RAISVGLVLGAFI 56

Query: 82  LTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTS 141
           L  ++GN+ VI +           +  +R LRTP N FI+NLA++D L+SFT  P     
Sbjct: 57  LFAIVGNILVILS-----------VACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAAL 105

Query: 142 SLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFV 201
            +   W+ G   C+ +A    L   +S+++L AI++DRY+ +   L    + ++R+A   
Sbjct: 106 EVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILA 165

Query: 202 LLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLI 261
           LL VW+ +   S+ P  GW    P         D          Y +      F++PL +
Sbjct: 166 LLSVWVLSTVISIGPLLGWKEPAPND-------DKECGVTEEPFYALFSSLGSFYIPLAV 218

Query: 262 IIYCYIFIFRAIRETGRALQ-------------------------TFGACKGNGES---- 292
           I+  Y  ++   + T + L+                         T  + K  G +    
Sbjct: 219 ILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSS 278

Query: 293 -LWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTP-YMSSVPAVIA 350
              +  +   E K AK + +V+ +F+L W P+  +AL   + ++ +  P  +  V   + 
Sbjct: 279 IAVKLFKFSREKKAAKTLGIVVGMFILCWLPF-FIALPLGSLFSTLKPPDAVFKVVFWLG 337

Query: 351 KASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSR 391
             ++  NPIIY  +  +++ A  + L C     G  RR  R
Sbjct: 338 YFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRR 378


>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
          Length = 345

 Score =  101 bits (252), Expect = 1e-21
 Identities = 73/271 (26%), Positives = 132/271 (48%), Gaps = 9/271 (3%)

Query: 106 MMQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFG 165
           ++  + L +P N  + +LA +DFL+  T  P     ++   W FG + C F+  C   F 
Sbjct: 57  ILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFC 116

Query: 166 ISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVP 225
            SS+  L  I++DRY+ +T PL      +   +   +   W+  L +S   F+  +    
Sbjct: 117 YSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFY--TGVYD 174

Query: 226 EGL-LTSCSWDYMSFTPAVRAYTMLLCCFV-FFLPLLIIIYCYIFIFRAIRETGRALQTF 283
           +GL   S + + +     V     +L  F+ FF+P  I+I  Y  IF   R   + ++  
Sbjct: 175 DGLEELSDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENT 234

Query: 284 GACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALV-AFAGYAHVLTP-Y 341
           G+   +    ++ +  + E K AK + + ++ F++SW PYS  +L+ AF G+   +TP  
Sbjct: 235 GSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGF---ITPAC 291

Query: 342 MSSVPAVIAKASAIHNPIIYAITHPKYRVAI 372
           +  +    A  ++  NP+IYA+ +P +R AI
Sbjct: 292 IYEICCWCAYYNSAMNPLIYALFYPWFRKAI 322


>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
          Length = 311

 Score =  100 bits (250), Expect = 2e-21
 Identities = 69/288 (23%), Positives = 141/288 (48%), Gaps = 28/288 (9%)

Query: 79  LVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQAPVF 138
           ++ +T ++GN+ V++           +++  + +RT  N F++NLA ++  M+     V 
Sbjct: 41  VIVVTSVVGNVVVMW-----------IILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVN 89

Query: 139 FTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRA 198
           FT +++ +W +G   C+F+ F       +S+ ++TA+A DRY+ I  PL     A+  + 
Sbjct: 90  FTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKV 149

Query: 199 AFVLLGVWLYALAWSLPP-FFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFL 257
             V+  +W+ AL  + P  ++  +  +P  ++    W         + Y + +   ++FL
Sbjct: 150 --VICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFL 207

Query: 258 PLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQ-RQRLQSECKMAKIMLLVILLF 316
           PLL+I Y Y  +            T  A +  G+S  +  +++ ++ K+ K+M++V+  F
Sbjct: 208 PLLVIGYAYTVVG----------ITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTF 257

Query: 317 VLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVI---AKASAIHNPIIY 361
            + W P+    L+ +      L  ++  V   I   A +S ++NPIIY
Sbjct: 258 AICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIY 305


>gi|4557865 somatostatin receptor 5 [Homo sapiens]
          Length = 364

 Score =  100 bits (249), Expect = 3e-21
 Identities = 97/357 (27%), Positives = 154/357 (43%), Gaps = 48/357 (13%)

Query: 26  PSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGM 85
           PSW  SS  + S  G   ++   AP   A A      V VP         + LLV   G+
Sbjct: 10  PSWNASSPGAASGGGDNRTLVGPAPSAGARA------VLVP--------VLYLLVCAAGL 55

Query: 86  LGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYK 145
            GN  VIY           V+++   ++T  N++I+NLAV+D L      P   T +   
Sbjct: 56  GGNTLVIY-----------VVLRFAKMKTVTNIYILNLAVADVLYMLG-LPFLATQNAAS 103

Query: 146 QWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGV 205
            W FG   C        +   +S+  LT +++DRYL +  PL++      R A       
Sbjct: 104 FWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAA 163

Query: 206 WLYALAWSLPPFFGWSAYVPEGLLTSCSW-DYMSFTPAVRAYTMLLCCFVFFLPLLIIIY 264
           W+ +L  SLP      A V EG   + SW + +    AV  + +      FF PLL+I  
Sbjct: 164 WVLSLCMSLPLLV--FADVQEGGTCNASWPEPVGLWGAV--FIIYTAVLGFFAPLLVICL 219

Query: 265 CYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYS 324
           CY+ I   +R  G  +     C           R +SE K+ +++L+V+L+F   W P+ 
Sbjct: 220 CYLLIVVKVRAAGVRV----GC----------VRRRSERKVTRMVLVVVLVFAGCWLPFF 265

Query: 325 AVALV--AFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCL 379
            V +V  A A      +  +     +++ A++  NP++Y      +R +  Q + CL
Sbjct: 266 TVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSF-QKVLCL 321


>gi|7669548 tachykinin receptor 3 [Homo sapiens]
          Length = 465

 Score = 99.8 bits (247), Expect = 5e-21
 Identities = 86/342 (25%), Positives = 154/342 (45%), Gaps = 36/342 (10%)

Query: 34  SSISSLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVIL-LVGLTGMLGNLTVI 92
           SS S+LG LP  SP     WA     L    V       L ++   +V    +LGNL VI
Sbjct: 53  SSPSALG-LPVASPAPSQPWAN----LTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVI 107

Query: 93  YTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGET 152
           +           +++  + +RT  N F++NLA SD  M+     V F  +L+ +W FG  
Sbjct: 108 W-----------IILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGAN 156

Query: 153 GCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAW 212
            C F  F       +S+ ++TAIA+DRY+ I  PL      S      V+  +W+ A   
Sbjct: 157 YCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKP--RLSATATKIVIGSIWILAFLL 214

Query: 213 SLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRA 272
           + P        V  G  T C   ++ +    + +      F + + ++I++YC+  +   
Sbjct: 215 AFPQCLYSKTKVMPG-RTLC---FVQWPEGPKQH------FTYHIIVIILVYCFPLLIMG 264

Query: 273 IRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVA-- 330
           I  T   +  +G            ++L+++ K+ K+M++V++ F + W PY    ++   
Sbjct: 265 ITYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAI 324

Query: 331 ---FAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYR 369
                 + ++   Y++S    +A +S ++NPIIY   + ++R
Sbjct: 325 YQQLNRWKYIQQVYLASF--WLAMSSTMYNPIIYCCLNKRFR 364


>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
          Length = 348

 Score = 99.8 bits (247), Expect = 5e-21
 Identities = 71/293 (24%), Positives = 141/293 (48%), Gaps = 7/293 (2%)

Query: 82  LTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTS 141
           L  +LG   V+  F   ++  +  ++  + L TP N  I +LA +DFL+  T  P     
Sbjct: 35  LYAVLGFGAVLAAFGNLLV--MIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVR 92

Query: 142 SLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFV 201
           S+   W FG++ C+F+      F  +S+  L  I++DRY+ +T PL      +   +   
Sbjct: 93  SVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGIC 152

Query: 202 LLGVWLYALAWSLPPFF-GWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLL 260
           ++  W +++ +S   F+ G +    E L+ + +       P  + + +LLC  +FF+P +
Sbjct: 153 IVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNW-VLLCFLLFFIPNV 211

Query: 261 IIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSW 320
            +++ Y  IF   +   R +++  +   +    ++ +  + E K AK + + +  F++SW
Sbjct: 212 AMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSW 271

Query: 321 APYSAVALVAFAGYAHVLT-PYMSSVPAVIAKASAIHNPIIYAITHPKYRVAI 372
            PY   A++    Y + +T PY+  +       ++  NP+IYA  +  +  AI
Sbjct: 272 LPYLVDAVI--DAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAI 322


>gi|5174595 melatonin receptor 1B [Homo sapiens]
          Length = 362

 Score = 99.0 bits (245), Expect = 9e-21
 Identities = 83/327 (25%), Positives = 148/327 (45%), Gaps = 37/327 (11%)

Query: 50  PGTWAAAWVPLPT-VDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQ 108
           PG W+ A    P+    P      L  V+++     ++GNL VI +           +++
Sbjct: 20  PG-WSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILS-----------VLR 67

Query: 109 SRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISS 168
           +R LR   N+F+++LA++D +++F   P+   +  Y  W  GE  C+  AF   L  I S
Sbjct: 68  NRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGS 127

Query: 169 MITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFF-GWSAYVPEG 227
           +  +TAIA++RY  I   +A   +  +      +  +WL  +   LP FF G   Y P  
Sbjct: 128 VFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPR- 186

Query: 228 LLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACK 287
            + SC++       A   YT  +    F LP+ ++ +CY+ I+  + +  R        K
Sbjct: 187 -IYSCTF----IQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARR--------K 233

Query: 288 GNGESLWQRQRLQ-SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSS-- 344
              ES   R  L+ S+ +    M +V ++F + WAP + + L A A     + P +    
Sbjct: 234 AKPES---RLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGL-AVAINPQEMAPQIPEGL 289

Query: 345 --VPAVIAKASAIHNPIIYAITHPKYR 369
                ++A  ++  N I+Y + +  +R
Sbjct: 290 FVTSYLLAYFNSCLNAIVYGLLNQNFR 316


>gi|32261309 G protein-coupled receptor 135 [Homo sapiens]
          Length = 494

 Score = 99.0 bits (245), Expect = 9e-21
 Identities = 93/325 (28%), Positives = 144/325 (44%), Gaps = 57/325 (17%)

Query: 76  VILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQA 135
           V+LL+ L   LGN  V+            V+++ R LRT  N FI++L++SD L +    
Sbjct: 109 VLLLIFLLSSLGNCAVM-----------GVIVKHRQLRTVTNAFILSLSLSDLLTALLCL 157

Query: 136 PVFFTSSLYKQWLFGETG--------------CEFYAFCGALFGISSMITLTAIALDRYL 181
           P  F        LF   G              C    F  + FGI S +++  I+LDRY 
Sbjct: 158 PAAFLD------LFTPPGGSAPAAAAGPWRGFCAASRFFSSCFGIVSTLSVALISLDRYC 211

Query: 182 VITRPLATFGVASKRRAAFVLLGVWLYALAWSLP------PFFGWSAYVPEGLLTSCSWD 235
            I RP        +RRA  +L G WL AL +SLP      P    +A    G L   S D
Sbjct: 212 AIVRPPRE--KIGRRRALQLLAGAWLTALGFSLPWELLGAPRELAAAQSFHGCLYRTSPD 269

Query: 236 YMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETG---RALQTFGACKGNGES 292
                 A     ++ C   + LP L++ +C+  I + +R +    R + T+         
Sbjct: 270 PAQLGAAFSVGLVVAC---YLLPFLLMCFCHYHICKTVRLSDVRVRPVNTYA-------- 318

Query: 293 LWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVL-TPYMSSVPAV-IA 350
             +  R  SE + A  +L++I+  +  W PY  + L+A A  A  +  P + SV AV + 
Sbjct: 319 --RVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAVWLT 376

Query: 351 KASAIHNPIIYAITHPKYRVAIAQH 375
            A+   NP+IYAI +P   + + ++
Sbjct: 377 WANGAINPVIYAIRNPNISMLLGRN 401


>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
          Length = 384

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 76/298 (25%), Positives = 133/298 (44%), Gaps = 29/298 (9%)

Query: 71  YTLGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLM 130
           Y +  V  ++ L G++GN+T+I  FC             +S+R   N+FI +LA+ D L+
Sbjct: 41  YVIPAVYGVIILIGLIGNITLIKIFCTV-----------KSMRNVPNLFISSLALGDLLL 89

Query: 131 SFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATF 190
             T APV  +  L  +WLFG  GC+   F        S+ TLTA++ DRY  I RP+   
Sbjct: 90  LITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQ 149

Query: 191 GVASKRRAAFVLLGVWLYALAWSLP--------PFFGWSAYVPEGLLTSCSWDYMSFTPA 242
              +  +       +W+ ++  ++P        PF   S         SC+    S    
Sbjct: 150 ASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEEST---NQTFISCAPYPHSNELH 206

Query: 243 VRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSE 302
            + ++M      + +PL II   Y FI + + ++   L   G       ++  +++++S 
Sbjct: 207 PKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEG-------NIHVKKQIESR 259

Query: 303 CKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPII 360
            ++AK +L+ + LF   W P   + L     Y+ V T  +  V ++ A+  A  N  +
Sbjct: 260 KRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCV 317


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.136    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,977,455
Number of Sequences: 37866
Number of extensions: 904305
Number of successful extensions: 8536
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 559
Number of HSP's successfully gapped in prelim test: 299
Number of HSP's that attempted gapping in prelim test: 6860
Number of HSP's gapped (non-prelim): 1290
length of query: 489
length of database: 18,247,518
effective HSP length: 106
effective length of query: 383
effective length of database: 14,233,722
effective search space: 5451515526
effective search space used: 5451515526
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.